term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Muscle contraction
| 10
| 27
| 2.598421
| 0.009365
|
P06753,Q13177,P09493,P60660,O43865,Q13153,P08133,P67936,Q9NYL9,P08670
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
146,346,69,74,577,294,687,305,544,63
|
577,686,1199,1920,146,1341,687,63,69,1168,1645,886,777,2037,1388,2295,74,305,1574,2565,294,346,1971,1844,2579,544,2238
|
0.7459093931850885,0.6320440740122428,0.22171244811574498,-0.18929860246142455,1.609734331636171,0.13043670441630822,0.6320440740122428,2.312532127633527,2.2445899756334495,0.2445261280106561,-0.029377801621022746,0.4497559749392965,0.5409161013840437,-0.2578692219726256,0.10761247991580983,-0.3950711452504818,2.1992869889805133,1.2008880747372999,0.016294229330441935,-0.5552441461593581,1.2236172265790646,1.1326894914941044,-0.21215324764925397,-0.14359595996140015,-0.5552441461593581,0.8142050472643398,-0.3493281113577081
| 3,376
|
Chaperone
| 44
| 108
| 2.5982
| 0.009371
|
Q99733,Q8WXX5,Q9BS26,Q99471,Q9H2J4,Q08752,Q13451,Q99832,O75347,O95433,O75937,P07900,Q9UL15,Q9HAV7,O15212,Q96A33,P78371,Q8N183,O95816,Q15084,Q9H3U1,P49368,Q15185,Q9Y4L1,Q96KC8,O75190,P61758,Q92688,Q9Y5J9,Q01105,Q9NQP4,O60884,P10809,P48643,O60925,Q9UHD1,O75880,Q9UHV9,Q16543,P78318,O95817,Q9UBK9,P50990,Q14696
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
271,522,139,270,798,752,787,931,530,915,282,663,165,555,43,698,432,185,178,842,700,446,843,469,467,828,345,876,746,600,98,724,857,860,230,767,112,512,500,497,618,252,623,650
|
1337,1304,1270,43,1308,1100,1235,724,230,3006,828,530,2155,112,282,1597,915,1518,1072,178,618,2926,1103,663,1073,1562,857,1797,1133,1753,2361,1603,3157,2440,2088,919,1107,1806,860,446,1685,623,1489,1877,1838,1570,3028,345,497,432,600,1012,752,2095,1176,3086,1576,787,2445,650,842,843,1615,2735,500,2216,185,2489,2709,1728,522,876,2766,698,1664,1328,467,1296,270,1986,2105,1160,271,931,139,1095,1298,2958,1461,798,700,555,2069,98,2962,1123,252,1992,1741,767,512,165,1064,1671,469,3272,746,1856
|
0.13043670441630822,0.15325880693776223,0.17607879404889298,2.561528394244356,0.15325880693776223,0.29014722557938266,0.19889667227848584,0.5864840833173061,1.382669872986797,-0.9905855228656107,0.4953400811340294,0.8142050472643398,-0.3264600029423213,1.8366222925568745,1.2463445321935245,-0.00654070501984235,0.4269608745762918,0.039127008246021396,0.31295465596021727,1.496224452836366,0.7003691781398825,-0.8759369071217561,0.29014722557938266,0.654821087209402,0.31295465596021727,0.016294229330441935,0.4725490417782299,-0.12074794835789432,0.2673377183743358,-0.09790213373324297,-0.4408233191309774,-0.00654070501984235,-1.2659996034795133,-0.48658469438810514,-0.2807305656763728,0.4269608745762918,0.29014722557938266,-0.12074794835789432,0.4725490417782299,0.9279923914863851,-0.05221706733189361,0.7003691781398825,0.061957638500894446,-0.1664461756216075,-0.14359595996140015,0.016294229330441935,-1.0135227149606314,1.1326894914941044,0.8597257693570096,0.9507440976385911,0.7231402673093839,0.35856331139810654,0.5637010941850982,-0.2807305656763728,0.2445261280106561,-1.105296684161769,0.016294229330441935,0.5409161013840437,-0.48658469438810514,0.6775961200071496,0.4953400811340294,0.4953400811340294,-0.00654070501984235,-0.6697234659246303,0.8597257693570096,-0.3493281113577081,1.496224452836366,-0.5094688519400632,-0.6468228743068464,-0.07505850905423944,0.8369663760218362,0.4725490417782299,-0.6926264377581445,0.6320440740122428,-0.029377801621022746,0.15325880693776223,0.9052387716538994,0.17607879404889298,1.291793624694478,-0.21215324764925397,-0.2807305656763728,0.2673377183743358,1.291793624694478,0.4269608745762918,1.6551258973436702,0.31295465596021727,0.17607879404889298,-0.8988616809189766,0.08478612682723895,0.5409161013840437,0.6320440740122428,0.791441777572769,-0.2578692219726256,1.9726722188066388,-0.8988616809189766,0.29014722557938266,1.3372353918837696,-0.21215324764925397,-0.07505850905423944,0.5637010941850982,0.8597257693570096,1.5643357067698693,0.33576001581343007,-0.029377801621022746,0.9052387716538994,-1.7258692943152663,0.5864840833173061,-0.14359595996140015
| 3,376
|
Pigment metabolic process
| 7
| 28
| 2.586551
| 0.009694
|
P09601,P36551,P22830,P00813,P53004,P30519,O00264
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
70,71,231,19,24,25,89
|
89,2320,1674,2085,19,1167,329,942,70,2245,2696,231,1001,25,3294,3214,1874,71,1761,24,2332,1930,1813,1737,2070,1591,720,3290
|
2.040674250545313,-0.4179460858744323,-0.05221706733189361,-0.2807305656763728,3.3976759190434085,0.2445261280106561,1.1554242122572953,0.40416373461270877,2.2445899756334495,-0.37219848961093516,-0.6468228743068464,1.382669872986797,0.35856331139810654,3.0363543565552815,-1.8640469790949206,-1.4498172605482251,-0.1664461756216075,2.2445899756334495,-0.09790213373324297,3.058948183621205,-0.4179460858744323,-0.18929860246142455,-0.12074794835789432,-0.07505850905423944,-0.2578692219726256,0.016294229330441935,0.6092650746483713,-1.8179762690089385
| 3,376
|
Proton transporting atp synthase complex
| 7
| 11
| 2.577052
| 0.009965
|
P00846,O75964,O75947,P25705,P48047,P24539,P06576
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
99,8,394,644,461,344,122
|
394,8,99,122,344,644,975,461,1926,667,1729
|
1.0189877874715023,4.186777541252852,1.9500014918186808,1.7458879968087067,1.1326894914941044,0.6775961200071496,0.38136454893617105,0.9052387716538994,-0.18929860246142455,0.654821087209402,-0.07505850905423944
| 3,376
|
Sensory neuropathy
| 13
| 37
| 2.574385
| 0.010042
|
P07384,P00846,P00403,O95831,O43933,P03886,O15269,Q9H0B6,O60313,O95140,Q96RL7,O94905,Q15041
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,99,254,7,578,547,514,608,428,404,92,343,477
|
514,1232,578,1595,428,343,404,7,254,99,547,128,1643,2086,973,2897,1874,1170,860,2981,1490,946,1965,2332,601,2016,1766,477,754,2217,2533,905,92,1371,608,2715,3022
|
0.8369663760218362,0.19889667227848584,0.7459093931850885,-0.00654070501984235,0.9507440976385911,1.1326894914941044,0.9962417903147566,4.321881386246311,1.3145154214917698,1.9500014918186808,0.791441777572769,1.700510440366334,-0.029377801621022746,-0.2807305656763728,0.38136454893617105,-0.830094721554977,-0.1664461756216075,0.2445261280106561,0.4725490417782299,-0.9447186346692006,0.061957638500894446,0.40416373461270877,-0.21215324764925397,-0.4179460858744323,0.7231402673093839,-0.23501011839942096,-0.09790213373324297,0.8824832327508613,0.5637010941850982,-0.3493281113577081,-0.5323553332283967,0.4497559749392965,2.040674250545313,0.13043670441630822,0.7231402673093839,-0.6468228743068464,-0.9905855228656107
| 3,376
|
Intra golgi traffic
| 9
| 15
| 2.559301
| 0.010488
|
Q96MW5,O95721,Q9NRW7,P54920,Q13190,O43752,Q9H9E3,P83436,P46459
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
553,444,556,141,150,326,52,320,583
|
1066,2550,326,579,444,2969,583,141,320,150,1418,553,2224,52,556
|
0.31295465596021727,-0.5552441461593581,1.1554242122572953,0.7459093931850885,0.9279923914863851,-0.9217889204720701,0.7459093931850885,1.632430994596424,1.1781570716463348,1.609734331636171,0.10761247991580983,0.791441777572769,-0.3493281113577081,2.471006836458075,0.791441777572769
| 3,376
|
Proton transporting two sector atpase complex proton transporting domain
| 6
| 11
| 2.554962
| 0.01062
|
P00846,O75964,O75947,Q93050,P61421,P24539
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
99,8,394,369,279,344
|
1862,394,8,99,344,461,1926,667,279,369,801
|
-0.1664461756216075,1.0189877874715023,4.186777541252852,1.9500014918186808,1.1326894914941044,0.9052387716538994,-0.18929860246142455,0.654821087209402,1.2690699965758048,1.0872144454036603,0.5409161013840437
| 3,376
|
Proton channel activity
| 7
| 11
| 2.547277
| 0.010857
|
P00846,O75964,O75947,P25705,P48047,P24539,P06576
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
99,8,394,644,461,344,122
|
394,8,99,122,344,644,975,1315,461,1926,667
|
1.0189877874715023,4.186777541252852,1.9500014918186808,1.7458879968087067,1.1326894914941044,0.6775961200071496,0.38136454893617105,0.15325880693776223,0.9052387716538994,-0.18929860246142455,0.654821087209402
| 3,376
|
Proton transporting atp synthase activity rotational mechanism
| 7
| 11
| 2.547277
| 0.010857
|
P00846,O75964,O75947,P25705,P48047,P24539,P06576
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
99,8,394,644,461,344,122
|
394,8,99,122,344,644,975,1315,461,1926,667
|
1.0189877874715023,4.186777541252852,1.9500014918186808,1.7458879968087067,1.1326894914941044,0.6775961200071496,0.38136454893617105,0.15325880693776223,0.9052387716538994,-0.18929860246142455,0.654821087209402
| 3,376
|
Positive regulation of cellular protein catabolic process
| 21
| 48
| 2.54587
| 0.010901
|
P17980,P51572,Q05397,P26038,P07900,P15311,Q96HY6,Q8IXJ6,Q9UNE7,O95816,P43686,Q9UNN5,O75150,Q4ZIN3,Q96QK1,Q9Y4X5,P62191,P62195,P49841,P35241,Q96JB5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
642,781,534,283,663,292,311,697,571,178,304,591,709,464,87,745,474,365,364,250,124
|
1100,804,709,2155,2392,178,1796,663,1562,292,642,283,250,1719,304,1924,1806,1443,2631,1281,364,781,2477,946,474,365,1391,2635,534,3124,2207,2165,2606,464,1408,697,311,124,87,2503,2823,1667,1591,2236,571,591,745,2317
|
0.29014722557938266,0.5181290990123865,0.6092650746483713,-0.3264600029423213,-0.4637028527189056,1.496224452836366,-0.12074794835789432,0.654821087209402,0.016294229330441935,1.2236172265790646,0.6775961200071496,1.2463445321935245,1.3372353918837696,-0.07505850905423944,1.2008880747372999,-0.18929860246142455,-0.12074794835789432,0.08478612682723895,-0.6010287988405737,0.17607879404889298,1.0872144454036603,0.5409161013840437,-0.5094688519400632,0.40416373461270877,0.8824832327508613,1.0872144454036603,0.10761247991580983,-0.6010287988405737,0.8142050472643398,-1.1741538836336023,-0.3493281113577081,-0.3264600029423213,-0.5781352986923748,0.9052387716538994,0.10761247991580983,0.6320440740122428,1.2008880747372999,1.7458879968087067,2.063338225377154,-0.5094688519400632,-0.7384395552892268,-0.029377801621022746,0.016294229330441935,-0.3493281113577081,0.7686765614043631,0.7459093931850885,0.5864840833173061,-0.3950711452504818
| 3,376
|
Snare complex
| 9
| 20
| 2.539509
| 0.011101
|
O95721,O60499,Q9P2W9,P54920,Q12846,Q13190,O43752,Q9NZ43,Q13277
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
444,12,14,141,265,150,326,290,475
|
2319,2077,2550,326,12,2358,579,444,945,141,265,150,475,2483,2485,1249,2224,290,14,2687
|
-0.4179460858744323,-0.2807305656763728,-0.5552441461593581,1.1554242122572953,3.713524418514359,-0.4408233191309774,0.7459093931850885,0.9279923914863851,0.40416373461270877,1.632430994596424,1.291793624694478,1.609734331636171,0.8824832327508613,-0.5094688519400632,-0.5094688519400632,0.19889667227848584,-0.3493281113577081,1.2463445321935245,3.5556354942395423,-0.6239246546713384
| 3,376
|
Autophagy
| 19
| 52
| 2.536602
| 0.011193
|
Q9NT62,Q8IWA4,A5D8V6,O43237,P21796,P68371,Q9H9H4,Q9NS69,O95140,Q15388,P07900,Q9NZ09,Q9Y6G9,Q9UQN3,P08670,P50542,O60664,O43633,Q8N4H5
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
656,790,513,639,20,784,409,22,404,164,663,821,574,704,63,65,723,594,234
|
513,639,594,723,806,404,2084,663,1073,63,1797,1441,20,1684,65,2046,946,1609,1143,1722,1011,784,2129,2130,1355,1356,2401,2402,164,2211,790,234,1695,3069,2496,2408,1986,2767,2106,1546,991,409,22,656,821,704,1303,1746,3091,2590,1950,574
|
0.8369663760218362,0.6775961200071496,0.7231402673093839,0.5864840833173061,0.5181290990123865,0.9962417903147566,-0.2807305656763728,0.654821087209402,0.31295465596021727,2.312532127633527,-0.12074794835789432,0.08478612682723895,3.3751044359501514,-0.05221706733189361,2.2672389993833404,-0.2578692219726256,0.40416373461270877,-0.00654070501984235,0.2673377183743358,-0.07505850905423944,0.35856331139810654,0.5409161013840437,-0.30359415686543867,-0.30359415686543867,0.13043670441630822,0.13043670441630822,-0.4637028527189056,-0.4637028527189056,1.5643357067698693,-0.3493281113577081,0.5409161013840437,1.382669872986797,-0.05221706733189361,-1.082349393180815,-0.5094688519400632,-0.4637028527189056,-0.21215324764925397,-0.6926264377581445,-0.2807305656763728,0.039127008246021396,0.38136454893617105,0.9962417903147566,3.352531486014035,0.6775961200071496,0.5181290990123865,0.6320440740122428,0.17607879404889298,-0.07505850905423944,-1.105296684161769,-0.5552441461593581,-0.18929860246142455,0.7686765614043631
| 3,376
|
Tp53 regulates metabolic genes
| 10
| 38
| 2.531105
| 0.01137
|
P27348,P63104,P00403,Q04917,P61981,P20674,P13073,O75880,P31946,P62258
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
156,419,254,169,333,199,395,112,147,90
|
2355,2285,1235,112,1237,2156,254,1919,2435,1832,943,395,971,199,156,2326,516,147,2781,1684,1606,2046,333,90,419,169,2129,2785,2484,2211,1851,1545,2147,1422,2381,1303,1828,1829
|
-0.4408233191309774,-0.3950711452504818,0.19889667227848584,1.8366222925568745,0.19889667227848584,-0.3264600029423213,1.3145154214917698,-0.18929860246142455,-0.48658469438810514,-0.14359595996140015,0.40416373461270877,1.0189877874715023,0.38136454893617105,1.4508080180236562,1.5870359038920763,-0.4179460858744323,0.8369663760218362,1.609734331636171,-0.7155317980973355,-0.05221706733189361,-0.00654070501984235,-0.2578692219726256,1.1554242122572953,2.040674250545313,0.9734938954710396,1.5416337356516463,-0.30359415686543867,-0.7155317980973355,-0.5094688519400632,-0.3493281113577081,-0.14359595996140015,0.039127008246021396,-0.30359415686543867,0.10761247991580983,-0.4408233191309774,0.17607879404889298,-0.12074794835789432,-0.12074794835789432
| 3,376
|
SNARE protein
| 7
| 14
| 2.530627
| 0.011386
|
O95721,O60499,Q9P2W9,Q12846,Q13190,O43752,Q13277
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
444,12,14,265,150,326,475
|
2319,2077,326,12,579,444,945,265,150,475,2485,1249,14,2687
|
-0.4179460858744323,-0.2807305656763728,1.1554242122572953,3.713524418514359,0.7459093931850885,0.9279923914863851,0.40416373461270877,1.291793624694478,1.609734331636171,0.8824832327508613,-0.5094688519400632,0.19889667227848584,3.5556354942395423,-0.6239246546713384
| 3,376
|
Cation transmembrane transport
| 38
| 127
| 2.529742
| 0.011415
|
P07384,P12235,P00403,Q96GC9,O75964,Q8IWX8,P46934,P46939,O75947,P25705,P13073,P21796,Q8N668,P61421,O43707,Q9UI12,P0DP25,Q6KCM7,P56385,Q04917,Q9HC07,Q9UDW1,P20674,P48047,Q9UJZ1,Q9NVV0,Q8N4V1,Q93034,P24539,P62258,P36543,Q8WWC4,P00846,Q13423,P31930,Q6P4Q7,O14745,P06576
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,129,254,389,8,652,11,646,394,644,395,20,538,279,529,559,664,551,667,169,207,79,199,461,611,349,86,606,344,90,598,356,99,354,232,108,614,122
|
2850,2355,2285,614,529,2115,748,1674,1998,1596,394,8,774,807,254,99,1199,1920,1274,2323,2828,122,1341,128,687,2118,916,664,1832,943,129,395,1168,1645,886,1313,2037,199,2038,2122,3141,20,344,644,2802,2439,2293,2556,1388,889,232,2294,2557,975,598,1315,1963,11,646,2043,461,780,1877,2295,2366,1926,667,279,3028,90,1394,3029,2336,1688,169,3124,3085,1245,354,1495,2935,2785,2168,1500,551,108,1452,2404,3114,1813,652,3052,86,538,925,356,606,389,1220,3135,1986,909,2579,2842,1545,3042,3372,3311,1665,2275,2068,207,1900,994,2714,2350,349,1124,79,767,559,611,3044,1593,1164,2318,2354
|
-0.7842622939081015,-0.4408233191309774,-0.3950711452504818,0.7003691781398825,0.8142050472643398,-0.30359415686543867,0.5637010941850982,-0.05221706733189361,-0.23501011839942096,-0.00654070501984235,1.0189877874715023,4.186777541252852,0.5409161013840437,0.5181290990123865,1.3145154214917698,1.9500014918186808,0.22171244811574498,-0.18929860246142455,0.17607879404889298,-0.4179460858744323,-0.7613497177385024,1.7458879968087067,0.13043670441630822,1.700510440366334,0.6320440740122428,-0.30359415686543867,0.4269608745762918,0.654821087209402,-0.14359595996140015,0.40416373461270877,1.700510440366334,1.0189877874715023,0.2445261280106561,-0.029377801621022746,0.4497559749392965,0.15325880693776223,-0.2578692219726256,1.4508080180236562,-0.2578692219726256,-0.30359415686543867,-1.2200715510997944,3.3751044359501514,1.1326894914941044,0.6775961200071496,-0.7384395552892268,-0.48658469438810514,-0.3950711452504818,-0.5552441461593581,0.10761247991580983,0.4497559749392965,1.382669872986797,-0.3950711452504818,-0.5552441461593581,0.38136454893617105,0.7231402673093839,0.15325880693776223,-0.21215324764925397,3.8037153417241023,0.6775961200071496,-0.2578692219726256,0.9052387716538994,0.5409161013840437,-0.1664461756216075,-0.3950711452504818,-0.4408233191309774,-0.18929860246142455,0.654821087209402,1.2690699965758048,-1.0135227149606314,2.040674250545313,0.10761247991580983,-1.0135227149606314,-0.4179460858744323,-0.05221706733189361,1.5416337356516463,-1.1741538836336023,-1.105296684161769,0.19889667227848584,1.1099529042532705,0.061957638500894446,-0.8759369071217561,-0.7155317980973355,-0.3264600029423213,0.061957638500894446,0.791441777572769,1.881979102274105,0.08478612682723895,-0.4637028527189056,-1.1511989198698822,-0.12074794835789432,0.6775961200071496,-1.0594046408731053,2.063338225377154,0.8142050472643398,0.4269608745762918,1.1099529042532705,0.7231402673093839,1.0417318922140226,0.22171244811574498,-1.1971114241452179,-0.21215324764925397,0.4497559749392965,-0.5552441461593581,-0.7613497177385024,0.039127008246021396,-1.036462417892556,-5.244320590828346,-1.9792747662426717,-0.029377801621022746,-0.37219848961093516,-0.2578692219726256,1.4508080180236562,-0.1664461756216075,0.38136454893617105,-0.6468228743068464,-0.4179460858744323,1.1326894914941044,0.29014722557938266,2.1539773900288672,0.5637010941850982,0.791441777572769,0.7231402673093839,-1.036462417892556,0.016294229330441935,0.2673377183743358,-0.3950711452504818,-0.4179460858744323
| 3,376
|
Cation transmembrane transporter activity
| 26
| 74
| 2.522798
| 0.011643
|
P12235,P00403,O75964,O75947,P25705,P13073,P61421,Q86VD7,Q9UI12,P56385,Q9Y5K8,Q9HC07,P20674,Q9UDW1,P48047,Q9NVV0,Q8N4V1,Q93034,P24539,P36543,P00846,Q13423,P31930,Q6P4Q7,Q93050,P06576
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
129,254,8,394,644,395,279,160,559,667,440,207,199,79,461,349,86,606,344,598,99,354,232,108,369,122
|
2285,2115,2551,394,8,774,254,99,1199,1920,2323,122,1341,687,2118,916,1832,129,395,1168,2037,199,2038,2122,344,644,889,232,2294,975,598,1315,2043,461,2366,1926,667,279,3028,3029,2336,1688,354,2785,2168,1500,108,1452,3114,1813,160,86,925,1091,606,369,3135,3042,3311,2275,2068,207,1900,994,349,1124,79,559,3044,3156,801,440,2318,2354
|
-0.3950711452504818,-0.30359415686543867,-0.5552441461593581,1.0189877874715023,4.186777541252852,0.5409161013840437,1.3145154214917698,1.9500014918186808,0.22171244811574498,-0.18929860246142455,-0.4179460858744323,1.7458879968087067,0.13043670441630822,0.6320440740122428,-0.30359415686543867,0.4269608745762918,-0.14359595996140015,1.700510440366334,1.0189877874715023,0.2445261280106561,-0.2578692219726256,1.4508080180236562,-0.2578692219726256,-0.30359415686543867,1.1326894914941044,0.6775961200071496,0.4497559749392965,1.382669872986797,-0.3950711452504818,0.38136454893617105,0.7231402673093839,0.15325880693776223,-0.2578692219726256,0.9052387716538994,-0.4408233191309774,-0.18929860246142455,0.654821087209402,1.2690699965758048,-1.0135227149606314,-1.0135227149606314,-0.4179460858744323,-0.05221706733189361,1.1099529042532705,-0.7155317980973355,-0.3264600029423213,0.061957638500894446,1.881979102274105,0.08478612682723895,-1.1511989198698822,-0.12074794835789432,1.5870359038920763,2.063338225377154,0.4269608745762918,0.31295465596021727,0.7231402673093839,1.0872144454036603,-1.1971114241452179,-1.036462417892556,-1.9792747662426717,-0.37219848961093516,-0.2578692219726256,1.4508080180236562,-0.1664461756216075,0.38136454893617105,1.1326894914941044,0.29014722557938266,2.1539773900288672,0.791441777572769,-1.036462417892556,-1.2430342742645197,0.5409161013840437,0.9507440976385911,-0.3950711452504818,-0.4179460858744323
| 3,376
|
Viral budding
| 8
| 14
| 2.510335
| 0.012062
|
O75351,O43633,Q9HD42,P46934,A5D8V6,Q6UWE0,Q9H9H4,Q9NP79
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
596,594,633,11,513,603,409,679
|
513,594,596,11,603,2265,2106,409,633,679,2421,1907,704,1746
|
0.8369663760218362,0.7231402673093839,0.7231402673093839,3.8037153417241023,0.7231402673093839,-0.37219848961093516,-0.2807305656763728,0.9962417903147566,0.7003691781398825,0.654821087209402,-0.4637028527189056,-0.1664461756216075,0.6320440740122428,-0.07505850905423944
| 3,376
|
Nadh dehydrogenase complex assembly
| 10
| 30
| 2.506741
| 0.012185
|
Q16718,P03886,O96000,Q9H061,O75306,Q8N183,O43676,Q9P0J0,O95168,Q7L592
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
233,547,515,78,197,185,21,88,303,424
|
2079,21,998,1998,197,805,303,1272,515,547,2325,861,1686,1084,233,1404,424,1773,185,1663,759,2345,78,1122,2543,3072,88,2717,1671,638
|
-0.2807305656763728,3.352531486014035,0.35856331139810654,-0.23501011839942096,1.4508080180236562,0.5181290990123865,1.2008880747372999,0.17607879404889298,0.8369663760218362,0.791441777572769,-0.4179460858744323,0.4725490417782299,-0.05221706733189361,0.31295465596021727,1.382669872986797,0.10761247991580983,0.9734938954710396,-0.09790213373324297,1.496224452836366,-0.029377801621022746,0.5637010941850982,-0.4179460858744323,2.1539773900288672,0.29014722557938266,-0.5323553332283967,-1.082349393180815,2.063338225377154,-0.6468228743068464,-0.029377801621022746,0.7003691781398825
| 3,376
|
Nyctalopia
| 10
| 30
| 2.494303
| 0.01262
|
P50542,Q8WWY3,O43837,O43172,Q10713,P38435,Q6P4Q7,Q9H9E3,O95140,P40855
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,236,196,411,550,331,108,52,404,562
|
411,196,578,885,2194,2433,1311,404,2004,2086,2514,2089,331,562,1170,1205,65,1243,550,2760,1017,2306,108,926,236,1251,1820,1988,52,2588
|
0.9734938954710396,1.4508080180236562,0.7459093931850885,0.4497559749392965,-0.3493281113577081,-0.48658469438810514,0.15325880693776223,0.9962417903147566,-0.23501011839942096,-0.2807305656763728,-0.5323553332283967,-0.2807305656763728,1.1554242122572953,0.7686765614043631,0.2445261280106561,0.22171244811574498,2.2672389993833404,0.19889667227848584,0.791441777572769,-0.6926264377581445,0.35856331139810654,-0.3950711452504818,1.881979102274105,0.4269608745762918,1.382669872986797,0.19889667227848584,-0.12074794835789432,-0.21215324764925397,2.471006836458075,-0.5552441461593581
| 3,376
|
Parkinubiquitin proteasomal system pathway
| 14
| 36
| 2.494041
| 0.01263
|
P62191,P48556,P38646,P68036,Q9UNM6,Q15008,P17980,P07437,P62195,Q9UNE7,P68371,P60604,P43686,O00231
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
474,157,919,947,276,895,642,941,365,571,784,278,304,340
|
340,1433,1337,1515,1193,1307,2155,941,1562,1797,642,1519,1717,1719,919,304,157,1762,1877,2561,278,474,365,1391,947,784,2095,1082,2096,1356,895,1544,1546,991,571,276
|
1.1326894914941044,0.08478612682723895,0.13043670441630822,0.039127008246021396,0.22171244811574498,0.15325880693776223,-0.3264600029423213,0.40416373461270877,0.016294229330441935,-0.12074794835789432,0.6775961200071496,0.039127008246021396,-0.07505850905423944,-0.07505850905423944,0.4269608745762918,1.2008880747372999,1.5870359038920763,-0.09790213373324297,-0.1664461756216075,-0.5552441461593581,1.2690699965758048,0.8824832327508613,1.0872144454036603,0.10761247991580983,0.40416373461270877,0.5409161013840437,-0.2807305656763728,0.31295465596021727,-0.2807305656763728,0.13043670441630822,0.4497559749392965,0.039127008246021396,0.039127008246021396,0.38136454893617105,0.7686765614043631,1.291793624694478
| 3,376
|
Nadh dehydrogenase activity
| 9
| 23
| 2.481089
| 0.013098
|
O95831,Q16718,P03886,O96000,O75306,Q9Y6M9,O43676,Q9P0J0,O95168
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
7,233,547,515,197,638,21,88,303
|
2355,2079,21,998,1998,197,805,303,661,1272,7,515,547,2693,2325,1925,861,1686,233,1404,88,2717,638
|
-0.4408233191309774,-0.2807305656763728,3.352531486014035,0.35856331139810654,-0.23501011839942096,1.4508080180236562,0.5181290990123865,1.2008880747372999,0.654821087209402,0.17607879404889298,4.321881386246311,0.8369663760218362,0.791441777572769,-0.6468228743068464,-0.4179460858744323,-0.18929860246142455,0.4725490417782299,-0.05221706733189361,1.382669872986797,0.10761247991580983,2.063338225377154,-0.6468228743068464,0.7003691781398825
| 3,376
|
Formation of atp by chemiosmotic coupling
| 7
| 10
| 2.476678
| 0.013261
|
P00846,O75964,O75947,P25705,P48047,P24539,P06576
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
99,8,394,644,461,344,122
|
394,8,99,122,344,644,975,461,1926,667
|
1.0189877874715023,4.186777541252852,1.9500014918186808,1.7458879968087067,1.1326894914941044,0.6775961200071496,0.38136454893617105,0.9052387716538994,-0.18929860246142455,0.654821087209402
| 3,376
|
Nucleoside triphosphate metabolic process
| 16
| 49
| 2.472987
| 0.013399
|
Q9ULC3,P00846,P00403,P08754,O75964,P04818,O75947,P25705,P48047,Q9UJZ1,P00813,P22392,O60313,P24539,P06576,Q9H773
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
659,99,254,445,8,107,394,644,461,611,19,430,428,344,122,31
|
2719,428,1861,394,8,254,2511,19,99,2198,107,122,2967,445,2471,2394,2779,2008,2514,430,944,344,644,1278,2555,1348,2664,975,1315,461,946,1319,1926,667,3011,2730,1574,1365,790,2174,2347,1299,31,2714,1060,2424,611,659,1554
|
-0.6697234659246303,0.9507440976385911,-0.1664461756216075,1.0189877874715023,4.186777541252852,1.3145154214917698,-0.5323553332283967,3.3976759190434085,1.9500014918186808,-0.3493281113577081,1.9046549378235165,1.7458879968087067,-0.9217889204720701,0.9279923914863851,-0.5094688519400632,-0.4637028527189056,-0.7155317980973355,-0.23501011839942096,-0.5323553332283967,0.9507440976385911,0.40416373461270877,1.1326894914941044,0.6775961200071496,0.17607879404889298,-0.5552441461593581,0.13043670441630822,-0.6239246546713384,0.38136454893617105,0.15325880693776223,0.9052387716538994,0.40416373461270877,0.15325880693776223,-0.18929860246142455,0.654821087209402,-0.9905855228656107,-0.6697234659246303,0.016294229330441935,0.13043670441630822,0.5409161013840437,-0.3264600029423213,-0.4179460858744323,0.17607879404889298,2.9007594347523846,-0.6468228743068464,0.33576001581343007,-0.4637028527189056,0.7231402673093839,0.6775961200071496,0.039127008246021396
| 3,376
|
Proteasome degradation
| 10
| 42
| 2.467137
| 0.01362
|
P48556,P61289,P46934,Q9UNM6,P28066,P62195,P04843,P43686,P04439,O00231
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
157,219,11,276,330,365,262,304,145,340
|
340,1433,1337,1305,1307,2155,145,262,831,665,1959,642,2324,1519,1870,1387,1482,1871,330,2629,1648,2203,1719,304,11,157,2951,2667,1762,2561,2296,219,474,365,1391,1208,1082,895,2840,1544,1063,276
|
1.1326894914941044,0.08478612682723895,0.13043670441630822,0.15325880693776223,0.15325880693776223,-0.3264600029423213,1.609734331636171,1.291793624694478,0.4953400811340294,0.654821087209402,-0.21215324764925397,0.6775961200071496,-0.4179460858744323,0.039127008246021396,-0.1664461756216075,0.10761247991580983,0.061957638500894446,-0.1664461756216075,1.1554242122572953,-0.6010287988405737,-0.029377801621022746,-0.3493281113577081,-0.07505850905423944,1.2008880747372999,3.8037153417241023,1.5870359038920763,-0.8988616809189766,-0.6239246546713384,-0.09790213373324297,-0.5552441461593581,-0.3950711452504818,1.4053843934011567,0.8824832327508613,1.0872144454036603,0.10761247991580983,0.22171244811574498,0.31295465596021727,0.4497559749392965,-0.7613497177385024,0.039127008246021396,0.33576001581343007,1.291793624694478
| 3,376
|
Positive regulation of protein catabolic process
| 25
| 68
| 2.462194
| 0.013809
|
P46934,P17980,Q13190,P14735,Q05397,P26038,P07900,P15311,Q96HY6,Q8IXJ6,Q9UNE7,O95816,P43686,P46459,Q9UNN5,Q13596,O75150,Q4ZIN3,Q96QK1,Q9P0J0,P62191,P62195,P49841,P35241,Q96JB5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
11,642,150,641,534,283,663,292,311,697,571,178,304,583,591,713,709,464,87,88,474,365,364,250,124
|
2850,1100,1830,804,709,2358,2155,2392,178,1796,663,1562,641,292,642,283,250,1719,304,1924,1806,583,11,1443,2631,1281,364,2981,781,2477,946,474,365,1391,2635,534,3124,2207,150,713,2252,2165,2606,1882,464,1408,2708,697,1847,311,1984,124,87,3300,2503,2823,88,1667,1591,1509,3168,2426,2236,571,591,745,2317,2239
|
-0.7842622939081015,0.29014722557938266,-0.14359595996140015,0.5181290990123865,0.6092650746483713,-0.4408233191309774,-0.3264600029423213,-0.4637028527189056,1.496224452836366,-0.12074794835789432,0.654821087209402,0.016294229330441935,0.6775961200071496,1.2236172265790646,0.6775961200071496,1.2463445321935245,1.3372353918837696,-0.07505850905423944,1.2008880747372999,-0.18929860246142455,-0.12074794835789432,0.7459093931850885,3.8037153417241023,0.08478612682723895,-0.6010287988405737,0.17607879404889298,1.0872144454036603,-0.9447186346692006,0.5409161013840437,-0.5094688519400632,0.40416373461270877,0.8824832327508613,1.0872144454036603,0.10761247991580983,-0.6010287988405737,0.8142050472643398,-1.1741538836336023,-0.3493281113577081,1.609734331636171,0.6092650746483713,-0.37219848961093516,-0.3264600029423213,-0.5781352986923748,-0.1664461756216075,0.9052387716538994,0.10761247991580983,-0.6468228743068464,0.6320440740122428,-0.14359595996140015,1.2008880747372999,-0.21215324764925397,1.7458879968087067,2.063338225377154,-1.8870866819578753,-0.5094688519400632,-0.7384395552892268,2.063338225377154,-0.029377801621022746,0.016294229330441935,0.061957638500894446,-1.288967548658644,-0.4637028527189056,-0.3493281113577081,0.7686765614043631,0.7459093931850885,0.5864840833173061,-0.3950711452504818,-0.3493281113577081
| 3,376
|
Mitochondrial membrane organization
| 19
| 50
| 2.456532
| 0.014029
|
P12235,Q8IWA4,Q9NX63,Q9NS69,O95140,O95202,P07900,Q13505,P0DP25,O60313,P45880,P50542,O14737,O75431,Q9P0J0,Q9Y5J9,Q8WWC4,Q16891,P49841
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,790,275,22,404,774,663,39,664,428,56,65,576,327,88,746,356,501,364
|
2911,576,428,327,806,404,774,1919,2323,663,1561,664,129,2556,2870,1717,919,1875,56,1443,1281,364,65,920,39,1084,2983,501,1499,1884,2572,3112,1621,790,1977,2056,356,1420,2583,22,1123,275,88,1591,1671,1164,1472,3272,746,1856
|
-0.8530145902549154,0.7459093931850885,0.9507440976385911,1.1554242122572953,0.5181290990123865,0.9962417903147566,0.5409161013840437,-0.18929860246142455,-0.4179460858744323,0.654821087209402,0.016294229330441935,0.654821087209402,1.700510440366334,-0.5552441461593581,-0.8071772923198322,-0.07505850905423944,0.4269608745762918,-0.1664461756216075,2.3804595810299363,0.08478612682723895,0.17607879404889298,1.0872144454036603,2.2672389993833404,0.4269608745762918,2.629402843859662,0.31295465596021727,-0.9447186346692006,0.8597257693570096,0.061957638500894446,-0.1664461756216075,-0.5552441461593581,-1.1511989198698822,-0.00654070501984235,0.5409161013840437,-0.21215324764925397,-0.2578692219726256,1.1099529042532705,0.10761247991580983,-0.5552441461593581,3.352531486014035,0.29014722557938266,1.291793624694478,2.063338225377154,0.016294229330441935,-0.029377801621022746,0.2673377183743358,0.08478612682723895,-1.7258692943152663,0.5864840833173061,-0.14359595996140015
| 3,376
|
Snap receptor activity
| 8
| 18
| 2.440163
| 0.014681
|
O95721,O60499,Q9P2W9,Q12846,Q13190,O43752,Q9NZ43,Q13277
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
444,12,14,265,150,326,290,475
|
2319,2077,2550,326,12,2358,579,444,945,265,150,475,2483,2485,1249,290,14,2687
|
-0.4179460858744323,-0.2807305656763728,-0.5552441461593581,1.1554242122572953,3.713524418514359,-0.4408233191309774,0.7459093931850885,0.9279923914863851,0.40416373461270877,1.291793624694478,1.609734331636171,0.8824832327508613,-0.5094688519400632,-0.5094688519400632,0.19889667227848584,1.2463445321935245,3.5556354942395423,-0.6239246546713384
| 3,376
|
Snare interactions in vesicular transport
| 8
| 18
| 2.440163
| 0.014681
|
O95721,O60499,Q9P2W9,Q12846,Q13190,O43752,Q9NZ43,Q13277
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
444,12,14,265,150,326,290,475
|
2319,2077,2550,326,12,2358,579,444,945,265,150,475,2483,2485,1249,290,14,2687
|
-0.4179460858744323,-0.2807305656763728,-0.5552441461593581,1.1554242122572953,3.713524418514359,-0.4408233191309774,0.7459093931850885,0.9279923914863851,0.40416373461270877,1.291793624694478,1.609734331636171,0.8824832327508613,-0.5094688519400632,-0.5094688519400632,0.19889667227848584,1.2463445321935245,3.5556354942395423,-0.6239246546713384
| 3,376
|
Oxidase
| 6
| 21
| 2.436934
| 0.014812
|
O43169,P36551,P20674,O75880,O15260,P14406
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
37,71,199,112,82,181
|
2285,1952,82,37,1235,112,1832,3225,2035,181,971,199,3010,71,2632,754,2785,222,1725,2021,1122
|
-0.3950711452504818,-0.21215324764925397,2.086000522614319,2.6520244957361756,0.19889667227848584,1.8366222925568745,-0.14359595996140015,-1.4957984470366237,-0.2578692219726256,1.496224452836366,0.38136454893617105,1.4508080180236562,-0.9905855228656107,2.2445899756334495,-0.6010287988405737,0.5637010941850982,-0.7155317980973355,1.4053843934011567,-0.07505850905423944,-0.23501011839942096,0.29014722557938266
| 3,376
|
Mitochondrial complex iii assembly
| 6
| 10
| 2.427911
| 0.015186
|
Q6DKK2,P31930,P22695,Q9UDW1,O14949,Q9BRT2
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
224,232,44,79,615,481
|
615,916,619,44,232,2043,224,481,79,1671
|
0.7003691781398825,0.4269608745762918,0.7003691781398825,2.561528394244356,1.382669872986797,-0.2578692219726256,1.4053843934011567,0.8824832327508613,2.1539773900288672,-0.029377801621022746
| 3,376
|
Atp metabolic process
| 32
| 114
| 2.427741
| 0.015193
|
P00403,O75964,Q9BSK2,O75947,O96000,P25705,P13073,O43676,O95182,Q6KCM7,P22695,P03886,Q9NTK5,P14406,O95168,Q9UDW1,P20674,O75306,P48047,Q9UJZ1,P24539,Q9BRT2,Q96QE5,P00846,P06576,Q9BRR6,O00429,Q16718,P31930,Q9Y6M9,O14949,P14927
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
254,8,9,394,515,644,395,21,661,551,44,547,568,181,303,79,199,197,461,611,344,481,226,99,122,103,351,233,232,638,615,619
|
351,2355,2285,615,2154,2079,21,998,829,1998,197,1675,805,1861,394,8,1597,303,661,1272,515,2798,254,940,2511,99,547,2198,2895,1919,1920,1274,1200,122,2967,2435,775,916,2006,2471,970,1562,1832,1797,395,181,1644,1798,619,971,1834,726,2086,2693,199,2038,44,344,644,1278,2325,2556,3294,1755,232,1874,1757,975,1075,1315,3251,1349,2043,461,1925,1007,861,920,2046,2161,946,1926,667,3196,1686,2599,3011,1354,1447,2129,233,1404,3031,551,2138,1813,2174,226,1986,103,481,9,3372,2583,1422,2714,568,79,2717,1591,2424,611,2351,638
|
1.1099529042532705,-0.4408233191309774,-0.3950711452504818,0.7003691781398825,-0.3264600029423213,-0.2807305656763728,3.352531486014035,0.35856331139810654,0.4953400811340294,-0.23501011839942096,1.4508080180236562,-0.05221706733189361,0.5181290990123865,-0.1664461756216075,1.0189877874715023,4.186777541252852,-0.00654070501984235,1.2008880747372999,0.654821087209402,0.17607879404889298,0.8369663760218362,-0.7384395552892268,1.3145154214917698,0.40416373461270877,-0.5323553332283967,1.9500014918186808,0.791441777572769,-0.3493281113577081,-0.830094721554977,-0.18929860246142455,-0.18929860246142455,0.17607879404889298,0.22171244811574498,1.7458879968087067,-0.9217889204720701,-0.48658469438810514,0.5409161013840437,0.4269608745762918,-0.23501011839942096,-0.5094688519400632,0.38136454893617105,0.016294229330441935,-0.14359595996140015,-0.12074794835789432,1.0189877874715023,1.496224452836366,-0.029377801621022746,-0.12074794835789432,0.7003691781398825,0.38136454893617105,-0.14359595996140015,0.5864840833173061,-0.2807305656763728,-0.6468228743068464,1.4508080180236562,-0.2578692219726256,2.561528394244356,1.1326894914941044,0.6775961200071496,0.17607879404889298,-0.4179460858744323,-0.5552441461593581,-1.8640469790949206,-0.09790213373324297,1.382669872986797,-0.1664461756216075,-0.09790213373324297,0.38136454893617105,0.31295465596021727,0.15325880693776223,-1.6338076191106943,0.13043670441630822,-0.2578692219726256,0.9052387716538994,-0.18929860246142455,0.35856331139810654,0.4725490417782299,0.4269608745762918,-0.2578692219726256,-0.3264600029423213,0.40416373461270877,-0.18929860246142455,0.654821087209402,-1.3808656899217036,-0.05221706733189361,-0.5781352986923748,-0.9905855228656107,0.13043670441630822,0.08478612682723895,-0.30359415686543867,1.382669872986797,0.10761247991580983,-1.0135227149606314,0.791441777572769,-0.30359415686543867,-0.12074794835789432,-0.3264600029423213,1.4053843934011567,-0.21215324764925397,1.9500014918186808,0.8824832327508613,4.119207289654426,-5.244320590828346,-0.5552441461593581,0.10761247991580983,-0.6468228743068464,0.7686765614043631,2.1539773900288672,-0.6468228743068464,0.016294229330441935,-0.4637028527189056,0.7231402673093839,-0.4179460858744323,0.7003691781398825
| 3,376
|
Membrane fusion
| 22
| 48
| 2.424822
| 0.015316
|
O60499,Q9P2W9,P54920,P31751,Q12846,Q13190,Q9NZ43,O60763,Q9UQN3,P04083,P46459,P08754,O95721,O95249,O43752,Q9H267,Q15075,Q13277,Q8WUH2,Q15276,O00429,Q9UHD1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
12,14,141,516,265,150,290,166,704,686,583,445,444,579,326,741,212,475,628,101,351,767
|
2319,351,2077,2550,326,856,12,166,2358,579,444,686,1341,445,516,583,2981,2598,945,141,2368,265,150,475,212,101,2483,2485,2708,1249,2488,790,628,2224,2987,2309,741,3088,290,2232,1469,14,767,1907,2687,3293,704,1746
|
-0.4179460858744323,1.1099529042532705,-0.2807305656763728,-0.5552441461593581,1.1554242122572953,0.4725490417782299,3.713524418514359,1.5416337356516463,-0.4408233191309774,0.7459093931850885,0.9279923914863851,0.6320440740122428,0.13043670441630822,0.9279923914863851,0.8369663760218362,0.7459093931850885,-0.9447186346692006,-0.5781352986923748,0.40416373461270877,1.632430994596424,-0.4408233191309774,1.291793624694478,1.609734331636171,0.8824832327508613,1.4280971068172954,1.9500014918186808,-0.5094688519400632,-0.5094688519400632,-0.6468228743068464,0.19889667227848584,-0.5094688519400632,0.5409161013840437,0.7003691781398825,-0.3493281113577081,-0.9447186346692006,-0.3950711452504818,0.5864840833173061,-1.105296684161769,1.2463445321935245,-0.3493281113577081,0.08478612682723895,3.5556354942395423,0.5637010941850982,-0.1664461756216075,-0.6239246546713384,-1.8410101788328443,0.6320440740122428,-0.07505850905423944
| 3,376
|
Actin filament depolymerization
| 9
| 22
| 2.421654
| 0.01545
|
Q13813,Q12792,Q96GD0,P47755,P52907,Q9Y281,Q9NYL9,P35241,Q01082
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
221,220,629,167,113,572,544,250,533
|
1099,2193,1800,250,2040,712,167,1318,113,893,1966,533,220,2566,221,1247,629,1629,544,1740,1379,572
|
0.29014722557938266,-0.3493281113577081,-0.12074794835789432,1.3372353918837696,-0.2578692219726256,0.6092650746483713,1.5416337356516463,0.15325880693776223,1.8366222925568745,0.4497559749392965,-0.21215324764925397,0.8142050472643398,1.4053843934011567,-0.5552441461593581,1.4053843934011567,0.19889667227848584,0.7003691781398825,-0.00654070501984235,0.8142050472643398,-0.07505850905423944,0.13043670441630822,0.7686765614043631
| 3,376
|
Golgi organization
| 16
| 65
| 2.419265
| 0.015552
|
P49257,Q96GC9,Q9UL15,Q8NHH9,Q14789,Q14999,Q9P2W9,Q08379,O60763,Q13190,Q9H4A6,Q9H9E3,O43752,O15260,Q7Z3D4,P83436
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
257,389,165,137,295,296,14,293,166,150,312,52,326,82,287,320
|
1192,1231,2428,803,82,1070,326,166,1750,2358,1200,974,1347,728,3132,1963,2631,257,751,780,2757,1172,1206,419,320,1286,293,2480,150,813,295,296,2133,3183,1577,1935,287,3001,2708,1625,2490,137,1728,1778,1892,389,1418,553,2377,2579,2987,817,2861,312,2886,1898,52,681,14,768,165,3293,1098,1429,883
|
0.22171244811574498,0.19889667227848584,-0.48658469438810514,0.5181290990123865,2.086000522614319,0.31295465596021727,1.1554242122572953,1.5416337356516463,-0.09790213373324297,-0.4408233191309774,0.22171244811574498,0.38136454893617105,0.13043670441630822,0.5864840833173061,-1.1971114241452179,-0.21215324764925397,-0.6010287988405737,1.3145154214917698,0.5637010941850982,0.5409161013840437,-0.6926264377581445,0.2445261280106561,0.22171244811574498,0.9734938954710396,1.1781570716463348,0.17607879404889298,1.2236172265790646,-0.5094688519400632,1.609734331636171,0.5181290990123865,1.2236172265790646,1.2236172265790646,-0.30359415686543867,-1.334911326938496,0.016294229330441935,-0.18929860246142455,1.2463445321935245,-0.9676508324618752,-0.6468228743068464,-0.00654070501984235,-0.5094688519400632,1.6551258973436702,-0.07505850905423944,-0.09790213373324297,-0.1664461756216075,1.0417318922140226,0.10761247991580983,0.791441777572769,-0.4408233191309774,-0.5552441461593581,-0.9447186346692006,0.5181290990123865,-0.7842622939081015,1.2008880747372999,-0.8071772923198322,-0.1664461756216075,2.471006836458075,0.654821087209402,3.5556354942395423,0.5637010941850982,1.5643357067698693,-1.8410101788328443,0.31295465596021727,0.10761247991580983,0.4725490417782299
| 3,376
|
Weakness of muscles of respiration
| 18
| 37
| 2.403177
| 0.016253
|
Q15067,P12235,P06753,Q9BQP7,Q969X5,P02545,O95831,P36551,Q9Y5L0,P53007,Q06210,Q9Y281,P55072,P08397,O95140,Q8TD16,P50402,P50570
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
754,129,146,590,451,218,7,71,963,862,625,572,946,942,404,161,779,780
|
2320,404,7,218,146,942,1643,1481,129,1519,973,71,1171,779,780,862,1490,946,2599,625,1398,2975,1495,754,2785,2482,1695,161,1777,451,590,2711,1739,572,1788,963,3022
|
-0.4179460858744323,0.9962417903147566,4.321881386246311,1.4053843934011567,1.609734331636171,0.40416373461270877,-0.029377801621022746,0.061957638500894446,1.700510440366334,0.039127008246021396,0.38136454893617105,2.2445899756334495,0.2445261280106561,0.5409161013840437,0.5409161013840437,0.4725490417782299,0.061957638500894446,0.40416373461270877,-0.5781352986923748,0.7003691781398825,0.10761247991580983,-0.9217889204720701,0.061957638500894446,0.5637010941850982,-0.7155317980973355,-0.5094688519400632,-0.05221706733189361,1.5870359038920763,-0.09790213373324297,0.9279923914863851,0.7459093931850885,-0.6468228743068464,-0.07505850905423944,0.7686765614043631,-0.09790213373324297,0.40416373461270877,-0.9905855228656107
| 3,376
|
Orc1 removal from chromatin
| 10
| 52
| 2.38675
| 0.016998
|
Q14566,P48556,P61289,Q9UNM6,P28066,Q92530,P62195,P43686,O00231,O43913
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
2,157,219,276,330,114,365,304,340,470
|
340,1433,1337,1515,1305,1307,470,2155,642,2324,808,1386,1870,1387,1482,1871,330,2629,1648,2203,1564,1485,2010,1719,304,157,2951,2667,1204,1762,2561,2296,219,474,365,1391,1111,1208,1082,2932,2569,2096,2,2605,895,114,2840,1544,1263,1063,276,2318
|
1.1326894914941044,0.08478612682723895,0.13043670441630822,0.039127008246021396,0.15325880693776223,0.15325880693776223,0.8824832327508613,-0.3264600029423213,0.6775961200071496,-0.4179460858744323,0.5181290990123865,0.10761247991580983,-0.1664461756216075,0.10761247991580983,0.061957638500894446,-0.1664461756216075,1.1554242122572953,-0.6010287988405737,-0.029377801621022746,-0.3493281113577081,0.016294229330441935,0.061957638500894446,-0.23501011839942096,-0.07505850905423944,1.2008880747372999,1.5870359038920763,-0.8988616809189766,-0.6239246546713384,0.22171244811574498,-0.09790213373324297,-0.5552441461593581,-0.3950711452504818,1.4053843934011567,0.8824832327508613,1.0872144454036603,0.10761247991580983,0.29014722557938266,0.22171244811574498,0.31295465596021727,-0.8759369071217561,-0.5552441461593581,-0.2807305656763728,5.625472030171659,-0.5781352986923748,0.4497559749392965,1.8366222925568745,-0.7613497177385024,0.039127008246021396,0.19889667227848584,0.33576001581343007,1.291793624694478,-0.3950711452504818
| 3,376
|
Cation channel activity
| 10
| 21
| 2.384788
| 0.017089
|
P00846,O75964,P56385,O75947,P25705,P48047,Q9NVV0,Q93034,P24539,P06576
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
99,8,667,394,644,461,349,606,344,122
|
394,8,99,122,1341,687,344,644,975,1315,461,1926,667,3028,1688,1500,925,606,349,1124,3044
|
1.0189877874715023,4.186777541252852,1.9500014918186808,1.7458879968087067,0.13043670441630822,0.6320440740122428,1.1326894914941044,0.6775961200071496,0.38136454893617105,0.15325880693776223,0.9052387716538994,-0.18929860246142455,0.654821087209402,-1.0135227149606314,-0.05221706733189361,0.061957638500894446,0.4269608745762918,0.7231402673093839,1.1326894914941044,0.29014722557938266,-1.036462417892556
| 3,376
|
Outer membrane
| 25
| 95
| 2.37835
| 0.01739
|
Q9GZY8,Q9NX63,Q9BWH2,P50416,P21796,Q9NS69,Q8TB36,O95140,Q9NZ45,Q8WY22,Q15388,O43169,Q13505,Q9HCL2,P45880,O60313,P09601,Q7Z434,O75431,Q96RL7,O00264,Q6SZW1,Q8N4H5,Q16891,O00429
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
273,275,400,517,20,22,539,404,28,29,164,37,39,175,56,428,70,202,327,92,89,355,234,501,351
|
1382,89,351,3364,37,428,1437,327,806,404,1598,2084,2690,2967,1561,70,2086,20,3294,1756,919,1684,1606,56,779,517,920,1965,2367,2333,2669,1449,39,536,164,1615,2983,501,1884,2572,3098,3112,694,355,1621,202,1022,790,1216,1977,2056,1368,234,3002,845,539,1091,1849,1777,29,2059,3069,2408,92,760,1628,909,3292,990,1420,3352,400,1373,1896,273,1032,175,1422,22,1854,1330,1123,852,3235,275,1507,28,1947,1301,3279,880,962,2890,1472,2910
|
0.10761247991580983,2.040674250545313,1.1099529042532705,-4.114766801780013,2.6520244957361756,0.9507440976385911,0.08478612682723895,1.1554242122572953,0.5181290990123865,0.9962417903147566,-0.00654070501984235,-0.2807305656763728,-0.6468228743068464,-0.9217889204720701,0.016294229330441935,2.2445899756334495,-0.2807305656763728,3.3751044359501514,-1.8640469790949206,-0.09790213373324297,0.4269608745762918,-0.05221706733189361,-0.00654070501984235,2.3804595810299363,0.5409161013840437,0.8369663760218362,0.4269608745762918,-0.21215324764925397,-0.4408233191309774,-0.4179460858744323,-0.6239246546713384,0.08478612682723895,2.629402843859662,0.8142050472643398,1.5643357067698693,-0.00654070501984235,-0.9447186346692006,0.8597257693570096,-0.1664461756216075,-0.5552441461593581,-1.1282465232303278,-1.1511989198698822,0.6320440740122428,1.1099529042532705,-0.00654070501984235,1.4508080180236562,0.35856331139810654,0.5409161013840437,0.22171244811574498,-0.21215324764925397,-0.2578692219726256,0.13043670441630822,1.382669872986797,-0.9676508324618752,0.4953400811340294,0.8142050472643398,0.31295465596021727,-0.14359595996140015,-0.09790213373324297,2.9233624102559466,-0.2578692219726256,-1.082349393180815,-0.4637028527189056,2.040674250545313,0.5637010941850982,-0.00654070501984235,0.4497559749392965,-1.8410101788328443,0.38136454893617105,0.10761247991580983,-2.7880413064895926,1.0189877874715023,0.13043670441630822,-0.1664461756216075,1.291793624694478,0.35856331139810654,1.5416337356516463,0.10761247991580983,3.352531486014035,-0.14359595996140015,0.15325880693776223,0.29014722557938266,0.4953400811340294,-1.518793113952308,1.291793624694478,0.061957638500894446,2.9685637646665515,-0.18929860246142455,0.17607879404889298,-1.77191707252357,0.4725490417782299,0.40416373461270877,-0.8071772923198322,0.08478612682723895,-0.830094721554977
| 3,376
|
Negative regulation of supramolecular fiber organization
| 16
| 51
| 2.369463
| 0.017814
|
Q13813,P16949,Q12792,Q9NQP4,O15212,Q99471,O60925,P47755,Q9UHV9,P52907,P61758,Q9BR76,Q13177,Q9NYL9,P35241,Q13136
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
221,34,220,98,43,270,230,167,512,113,345,540,346,544,250,57
|
1099,43,1306,230,1750,1310,3080,1797,34,1683,250,2040,712,2727,167,1318,113,893,1569,345,1722,533,1012,1841,220,2566,57,346,221,813,952,1247,1288,3001,2790,2742,270,1629,540,2958,98,702,3353,544,681,1740,1379,512,1509,2507,3282
|
0.29014722557938266,2.561528394244356,0.15325880693776223,1.382669872986797,-0.09790213373324297,0.15325880693776223,-1.105296684161769,-0.12074794835789432,2.765109185211371,-0.05221706733189361,1.3372353918837696,-0.2578692219726256,0.6092650746483713,-0.6697234659246303,1.5416337356516463,0.15325880693776223,1.8366222925568745,0.4497559749392965,0.016294229330441935,1.1326894914941044,-0.07505850905423944,0.8142050472643398,0.35856331139810654,-0.14359595996140015,1.4053843934011567,-0.5552441461593581,2.3804595810299363,1.1326894914941044,1.4053843934011567,0.5181290990123865,0.40416373461270877,0.19889667227848584,0.17607879404889298,-0.9676508324618752,-0.7155317980973355,-0.6697234659246303,1.291793624694478,-0.00654070501984235,0.8142050472643398,-0.8988616809189766,1.9726722188066388,0.6320440740122428,-2.8343790211123925,0.8142050472643398,0.654821087209402,-0.07505850905423944,0.13043670441630822,0.8597257693570096,0.061957638500894446,-0.5094688519400632,-1.7949452375604908
| 3,376
|
Outer mitochondrial membrane protein complex
| 6
| 17
| 2.357137
| 0.018416
|
Q15388,Q13505,Q8N4H5,Q9NX63,O75431,Q9NS69
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
164,39,234,275,327,22
|
327,806,2084,919,39,164,501,2572,3112,1621,790,234,1420,22,1123,275,1472
|
1.1554242122572953,0.5181290990123865,-0.2807305656763728,0.4269608745762918,2.629402843859662,1.5643357067698693,0.8597257693570096,-0.5552441461593581,-1.1511989198698822,-0.00654070501984235,0.5409161013840437,1.382669872986797,0.10761247991580983,3.352531486014035,0.29014722557938266,1.291793624694478,0.08478612682723895
| 3,376
|
er
| 16
| 85
| 2.356979
| 0.018424
|
Q9NQC3,Q07065,O96005,O15121,Q8NHH9,O60499,Q9P2W9,Q969Q5,O15173,Q13190,Q15392,P04843,Q99640,Q8N4V1,Q9P0I2,O00264
|
Localization
|
OpenCell Localization
|
opencell_localization
|
392,130,132,352,137,12,14,13,110,150,184,262,280,86,229,89
|
89,1951,2623,352,110,514,1232,965,12,1196,2358,1676,2081,1751,132,2690,262,831,2437,2158,1801,2440,1651,1003,3319,1565,751,2634,2598,781,946,3264,1967,1172,1654,3241,1809,1765,1571,1526,130,150,2671,1150,477,2133,184,1724,2210,896,2573,981,2610,1623,2764,1887,86,2057,1847,137,2492,1154,13,524,698,389,927,280,2344,2182,3101,1097,993,2277,2278,392,1989,1061,229,2232,14,3044,2465,801,964
|
2.040674250545313,-0.21215324764925397,-0.6010287988405737,1.1099529042532705,1.859301555293337,0.8369663760218362,0.19889667227848584,0.38136454893617105,3.713524418514359,0.22171244811574498,-0.4408233191309774,-0.05221706733189361,-0.2807305656763728,-0.09790213373324297,1.6778190444254801,-0.6468228743068464,1.291793624694478,0.4953400811340294,-0.48658469438810514,-0.3264600029423213,-0.12074794835789432,-0.48658469438810514,-0.029377801621022746,0.35856331139810654,-2.071510292020483,0.016294229330441935,0.5637010941850982,-0.6010287988405737,-0.5781352986923748,0.5409161013840437,0.40416373461270877,-1.702849657699171,-0.21215324764925397,0.2445261280106561,-0.029377801621022746,-1.564790649040453,-0.12074794835789432,-0.09790213373324297,0.016294229330441935,0.039127008246021396,1.700510440366334,1.609734331636171,-0.6239246546713384,0.2673377183743358,0.8824832327508613,-0.30359415686543867,1.496224452836366,-0.07505850905423944,-0.3493281113577081,0.4497559749392965,-0.5552441461593581,0.38136454893617105,-0.5781352986923748,-0.00654070501984235,-0.6926264377581445,-0.1664461756216075,2.063338225377154,-0.2578692219726256,-0.14359595996140015,1.6551258973436702,-0.5094688519400632,0.2673377183743358,3.5556354942395423,0.8369663760218362,0.6320440740122428,1.0417318922140226,0.4269608745762918,1.2690699965758048,-0.4179460858744323,-0.3264600029423213,-1.1282465232303278,0.31295465596021727,0.38136454893617105,-0.37219848961093516,-0.37219848961093516,1.0417318922140226,-0.21215324764925397,0.33576001581343007,1.4053843934011567,-0.3493281113577081,3.5556354942395423,-1.036462417892556,-0.48658469438810514,0.5409161013840437,0.40416373461270877
| 3,376
|
Negative regulation of actin filament depolymerization
| 6
| 17
| 2.351124
| 0.018717
|
Q13813,Q12792,P47755,P52907,Q9NYL9,P35241
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
221,220,167,113,544,250
|
1099,250,2040,712,167,1318,113,893,533,220,2566,221,1247,1629,544,1740,1379
|
0.29014722557938266,1.3372353918837696,-0.2578692219726256,0.6092650746483713,1.5416337356516463,0.15325880693776223,1.8366222925568745,0.4497559749392965,0.8142050472643398,1.4053843934011567,-0.5552441461593581,1.4053843934011567,0.19889667227848584,-0.00654070501984235,0.8142050472643398,-0.07505850905423944,0.13043670441630822
| 3,376
|
Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
| 8
| 15
| 2.346501
| 0.018951
|
O75351,O43633,Q9HD42,P46934,A5D8V6,Q9H9H4,Q9UQN3,Q9BRG1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
596,594,633,11,513,409,704,761
|
513,594,596,11,1252,2106,761,409,633,821,2421,1907,704,1267,1746
|
0.8369663760218362,0.7231402673093839,0.7231402673093839,3.8037153417241023,0.19889667227848584,-0.2807305656763728,0.5637010941850982,0.9962417903147566,0.7003691781398825,0.5181290990123865,-0.4637028527189056,-0.1664461756216075,0.6320440740122428,0.19889667227848584,-0.07505850905423944
| 3,376
|
Spectrin repeat [IPR002017]
| 6
| 9
| 2.339093
| 0.019331
|
Q9UPN3,Q13813,P12814,Q03001,Q01082,O43707
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
660,221,248,601,533,529
|
1099,529,248,646,533,601,221,1777,660
|
0.29014722557938266,0.8142050472643398,1.3372353918837696,0.6775961200071496,0.8142050472643398,0.7231402673093839,1.4053843934011567,-0.09790213373324297,0.6775961200071496
| 3,376
|
Cell cell recognition
| 8
| 14
| 2.318254
| 0.020436
|
P49368,P17931,P48643,P78371,Q14157,P45880,P50990,P26038
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
446,725,860,432,210,56,623,283
|
1270,2198,725,1753,283,56,860,446,623,1489,432,1245,210,931
|
0.17607879404889298,-0.3493281113577081,0.5864840833173061,-0.09790213373324297,1.2463445321935245,2.3804595810299363,0.4725490417782299,0.9279923914863851,0.7003691781398825,0.061957638500894446,0.9507440976385911,0.19889667227848584,1.4280971068172954,0.4269608745762918
| 3,376
|
Establishment of protein localization to membrane
| 35
| 96
| 2.311552
| 0.020802
|
Q9UPN3,Q9NT62,Q9GZY8,A5D8V6,P31751,O75608,Q9NS69,Q9H9H4,Q01082,Q15629,P07900,P0DP25,Q9H4A6,Q96A33,O94826,O15027,O60725,O43681,P40855,P46459,P49069,P50542,O14737,P43307,Q8N3F8,Q8N4V1,Q96QK1,Q9P0J0,Q9P0I2,Q9Y5J9,Q15041,Q8WWC4,Q13277,Q4V328,Q9UHD1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
660,656,273,513,516,640,22,409,533,35,663,664,312,698,806,803,429,684,562,583,689,65,576,77,85,86,87,88,229,746,477,356,475,502,767
|
513,2548,2911,2151,576,803,1913,965,684,1100,429,640,1339,806,1598,1920,663,2437,664,2802,2870,1649,516,1717,2558,562,2042,77,1806,583,689,2331,65,2981,2831,3264,2368,1967,1654,3028,2635,3029,1688,533,2637,475,2166,2254,1150,477,2019,1084,35,2483,2370,1529,502,1884,2573,1622,2488,1625,85,86,2057,845,356,698,87,1506,2309,273,1988,1057,312,1898,409,994,932,2278,22,656,229,88,1741,1127,767,1670,3168,660,1671,2353,1472,3272,746,1856
|
0.8369663760218362,-0.5552441461593581,-0.8530145902549154,-0.3264600029423213,0.7459093931850885,0.5181290990123865,-0.18929860246142455,0.38136454893617105,0.6320440740122428,0.29014722557938266,0.9507440976385911,0.6775961200071496,0.13043670441630822,0.5181290990123865,-0.00654070501984235,-0.18929860246142455,0.654821087209402,-0.48658469438810514,0.654821087209402,-0.7384395552892268,-0.8071772923198322,-0.029377801621022746,0.8369663760218362,-0.07505850905423944,-0.5552441461593581,0.7686765614043631,-0.2578692219726256,2.1766330180587605,-0.12074794835789432,0.7459093931850885,0.6320440740122428,-0.4179460858744323,2.2672389993833404,-0.9447186346692006,-0.7613497177385024,-1.702849657699171,-0.4408233191309774,-0.21215324764925397,-0.029377801621022746,-1.0135227149606314,-0.6010287988405737,-1.0135227149606314,-0.05221706733189361,0.8142050472643398,-0.6010287988405737,0.8824832327508613,-0.3264600029423213,-0.37219848961093516,0.2673377183743358,0.8824832327508613,-0.23501011839942096,0.31295465596021727,2.765109185211371,-0.5094688519400632,-0.4408233191309774,0.039127008246021396,0.8597257693570096,-0.1664461756216075,-0.5552441461593581,-0.00654070501984235,-0.5094688519400632,-0.00654070501984235,2.063338225377154,2.063338225377154,-0.2578692219726256,0.4953400811340294,1.1099529042532705,0.6320440740122428,2.063338225377154,0.061957638500894446,-0.3950711452504818,1.291793624694478,-0.21215324764925397,0.33576001581343007,1.2008880747372999,-0.1664461756216075,0.9962417903147566,0.38136454893617105,0.4269608745762918,-0.37219848961093516,3.352531486014035,0.6775961200071496,1.4053843934011567,2.063338225377154,-0.07505850905423944,0.29014722557938266,0.5637010941850982,-0.029377801621022746,-1.288967548658644,0.6775961200071496,-0.029377801621022746,-0.4179460858744323,0.08478612682723895,-1.7258692943152663,0.5864840833173061,-0.14359595996140015
| 3,376
|
Protein import
| 33
| 86
| 2.309306
| 0.020927
|
O60830,Q9ULC3,Q99567,Q99595,O95831,Q7Z3B4,P57740,Q9NS69,Q15388,P07900,Q9HAV7,Q9BVL2,O94826,P40855,P50542,P55060,Q9UKG1,O43933,O14737,Q7Z434,O00410,P61960,O15397,Q8N1F7,Q8WUM0,P02545,Q08209,Q13043,P10809,Q9UHD1,O95817,P12270,Q99623
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,659,390,6,7,267,648,22,164,663,555,438,806,562,65,447,720,578,576,202,825,200,826,604,874,218,732,733,857,767,618,247,909
|
825,1067,576,3210,1706,826,1435,578,2626,1558,0,885,1860,806,2289,2082,618,7,2084,218,1919,1200,663,1073,857,1797,247,3179,3141,1717,2871,1442,3251,562,3260,2476,65,2559,1141,2206,447,648,200,2333,2730,2804,732,733,1398,2567,1355,1149,3095,164,2523,1018,1499,3183,2170,267,202,2339,604,2709,1290,874,1817,1664,1543,2818,390,6,909,438,2183,2416,555,22,2230,767,1993,720,2028,659,1472,963
|
0.4953400811340294,0.31295465596021727,0.7459093931850885,-1.4498172605482251,-0.07505850905423944,0.4953400811340294,0.08478612682723895,0.7459093931850885,-0.6010287988405737,0.016294229330441935,8.666912565323075,0.4497559749392965,-0.1664461756216075,0.5181290990123865,-0.3950711452504818,-0.2807305656763728,0.7003691781398825,4.321881386246311,-0.2807305656763728,1.4053843934011567,-0.18929860246142455,0.22171244811574498,0.654821087209402,0.31295465596021727,0.4725490417782299,-0.12074794835789432,1.3372353918837696,-1.334911326938496,-1.2200715510997944,-0.07505850905423944,-0.8071772923198322,0.08478612682723895,-1.6338076191106943,0.7686765614043631,-1.6798328406028724,-0.5094688519400632,2.2672389993833404,-0.5552441461593581,0.2673377183743358,-0.3493281113577081,0.9279923914863851,0.6775961200071496,1.4508080180236562,-0.4179460858744323,-0.6697234659246303,-0.7384395552892268,0.5864840833173061,0.5864840833173061,0.10761247991580983,-0.5552441461593581,0.13043670441630822,0.2673377183743358,-1.1282465232303278,1.5643357067698693,-0.5323553332283967,0.35856331139810654,0.061957638500894446,-1.334911326938496,-0.3264600029423213,1.291793624694478,1.4508080180236562,-0.4179460858744323,0.7231402673093839,-0.6468228743068464,0.17607879404889298,0.4725490417782299,-0.12074794835789432,-0.029377801621022746,0.039127008246021396,-0.7384395552892268,1.0417318922140226,4.6369364917203,0.4497559749392965,0.9507440976385911,-0.3264600029423213,-0.4637028527189056,0.791441777572769,3.352531486014035,-0.3493281113577081,0.5637010941850982,-0.21215324764925397,0.6092650746483713,-0.23501011839942096,0.6775961200071496,0.08478612682723895,0.40416373461270877
| 3,376
|
Abnormal left ventricle morphology
| 8
| 32
| 2.299829
| 0.021458
|
P12235,O00170,P00403,Q15233,Q969Y2,O75880,O75431,Q07021
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
129,187,254,171,399,112,327,149
|
187,2510,2655,1557,829,327,1862,112,254,547,3302,1481,129,1275,1682,1755,1170,1490,1965,1525,149,2878,171,420,1363,982,1366,2261,399,1371,1988,2381
|
1.4735171317837568,-0.5323553332283967,-0.6239246546713384,0.016294229330441935,0.4953400811340294,1.1554242122572953,-0.1664461756216075,1.8366222925568745,1.3145154214917698,0.791441777572769,-1.933174844644704,0.061957638500894446,1.700510440366334,0.17607879404889298,-0.05221706733189361,-0.09790213373324297,0.2445261280106561,0.061957638500894446,-0.21215324764925397,0.039127008246021396,1.609734331636171,-0.8071772923198322,1.5416337356516463,0.9734938954710396,0.13043670441630822,0.38136454893617105,0.13043670441630822,-0.37219848961093516,1.0189877874715023,0.13043670441630822,-0.21215324764925397,-0.4408233191309774
| 3,376
|
Increased csf lactate
| 9
| 58
| 2.299583
| 0.021472
|
P30084,P00846,O95831,Q8NI60,O75306,Q8N183,O43676,Q9P0J0,Q8NCW5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
189,99,7,111,197,185,21,88,192
|
2284,2355,1309,21,998,1235,1998,197,805,1272,7,515,254,99,547,1921,395,2693,2325,917,189,1755,729,2898,1606,1925,3195,861,1567,1686,2441,2785,1404,953,3271,1813,982,1773,185,192,111,1663,2533,759,1851,2884,928,2841,1545,2345,1900,2069,1903,2543,3072,88,2717,638
|
-0.3950711452504818,-0.4408233191309774,0.15325880693776223,3.352531486014035,0.35856331139810654,0.19889667227848584,-0.23501011839942096,1.4508080180236562,0.5181290990123865,0.17607879404889298,4.321881386246311,0.8369663760218362,1.3145154214917698,1.9500014918186808,0.791441777572769,-0.18929860246142455,1.0189877874715023,-0.6468228743068464,-0.4179460858744323,0.4269608745762918,1.4735171317837568,-0.09790213373324297,0.5864840833173061,-0.830094721554977,-0.00654070501984235,-0.18929860246142455,-1.3808656899217036,0.4725490417782299,0.016294229330441935,-0.05221706733189361,-0.48658469438810514,-0.7155317980973355,0.10761247991580983,0.40416373461270877,-1.7258692943152663,-0.12074794835789432,0.38136454893617105,-0.09790213373324297,1.496224452836366,1.4735171317837568,1.859301555293337,-0.029377801621022746,-0.5323553332283967,0.5637010941850982,-0.14359595996140015,-0.8071772923198322,0.4269608745762918,-0.7613497177385024,0.039127008246021396,-0.4179460858744323,-0.1664461756216075,-0.2578692219726256,-0.1664461756216075,-0.5323553332283967,-1.082349393180815,2.063338225377154,-0.6468228743068464,0.7003691781398825
| 3,376
|
Ophthalmoparesis
| 23
| 81
| 2.299517
| 0.021476
|
P12235,P00403,Q9GZY8,Q07021,P06753,Q15149,Q10713,O43172,P03886,Q9UNE7,Q8N183,O60313,P30084,O00170,O43837,O75306,Q86U42,Q9P0J0,P00846,Q8WWY3,O00429,Q969G3,O15460
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
129,254,273,149,146,536,550,411,547,571,185,428,189,187,196,197,347,88,99,236,351,251,125
|
187,351,2355,2320,125,411,998,1235,196,428,1998,197,805,2194,2433,1043,1311,1272,254,99,547,1796,146,1921,3224,129,2693,2514,1682,1799,2725,2325,917,189,1755,2089,1925,1205,780,2126,862,1490,625,149,550,894,1766,3254,536,2785,1017,1404,3307,2306,1813,347,2955,185,3002,1695,236,1251,251,759,1729,1371,2223,2842,590,1545,2345,273,1988,2226,1162,88,2381,1739,2717,571,1164
|
1.4735171317837568,1.1099529042532705,-0.4408233191309774,-0.4179460858744323,1.7232000896678,0.9734938954710396,0.35856331139810654,0.19889667227848584,1.4508080180236562,0.9507440976385911,-0.23501011839942096,1.4508080180236562,0.5181290990123865,-0.3493281113577081,-0.48658469438810514,0.33576001581343007,0.15325880693776223,0.17607879404889298,1.3145154214917698,1.9500014918186808,0.791441777572769,-0.12074794835789432,1.609734331636171,-0.18929860246142455,-1.4957984470366237,1.700510440366334,-0.6468228743068464,-0.5323553332283967,-0.05221706733189361,-0.12074794835789432,-0.6697234659246303,-0.4179460858744323,0.4269608745762918,1.4735171317837568,-0.09790213373324297,-0.2807305656763728,-0.18929860246142455,0.22171244811574498,0.5409161013840437,-0.30359415686543867,0.4725490417782299,0.061957638500894446,0.7003691781398825,1.609734331636171,0.791441777572769,0.4497559749392965,-0.09790213373324297,-1.6338076191106943,0.8142050472643398,-0.7155317980973355,0.35856331139810654,0.10761247991580983,-1.956223329305267,-0.3950711452504818,-0.12074794835789432,1.1326894914941044,-0.8988616809189766,1.496224452836366,-0.9676508324618752,-0.05221706733189361,1.382669872986797,0.19889667227848584,1.3372353918837696,0.5637010941850982,-0.07505850905423944,0.13043670441630822,-0.3493281113577081,-0.7613497177385024,0.7459093931850885,0.039127008246021396,-0.4179460858744323,1.291793624694478,-0.21215324764925397,-0.3493281113577081,0.2673377183743358,2.063338225377154,-0.4408233191309774,-0.07505850905423944,-0.6468228743068464,0.7686765614043631,0.2673377183743358
| 3,376
|
Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]
| 6
| 7
| 2.28646
| 0.022227
|
Q9H223,Q8IWA4,O00429,Q9H4M9,O60313,O95140
|
Sequence
|
InterPro Domain
|
interpro_domain
|
525,790,351,299,428,404
|
351,428,404,780,790,525,299
|
1.1099529042532705,0.9507440976385911,0.9962417903147566,0.5409161013840437,0.5409161013840437,0.8369663760218362,1.2236172265790646
| 3,376
|
Dynamin, N-terminal [IPR045063]
| 6
| 7
| 2.28646
| 0.022227
|
Q9H223,Q8IWA4,O00429,Q9H4M9,O60313,O95140
|
Sequence
|
InterPro Domain
|
interpro_domain
|
525,790,351,299,428,404
|
351,428,404,780,790,525,299
|
1.1099529042532705,0.9507440976385911,0.9962417903147566,0.5409161013840437,0.5409161013840437,0.8369663760218362,1.2236172265790646
| 3,376
|
Horizontal nystagmus
| 10
| 25
| 2.282657
| 0.022451
|
P20700,P50542,P00846,O95831,O00429,Q9H061,Q9UNE7,P52815,O60313,O94905
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
155,65,99,7,351,78,571,495,428,343
|
2911,351,2654,1099,428,343,7,99,1796,3268,155,1442,65,495,1568,2519,2785,586,2858,2269,78,2715,1124,1947,571
|
-0.8530145902549154,1.1099529042532705,-0.6239246546713384,0.29014722557938266,0.9507440976385911,1.1326894914941044,4.321881386246311,1.9500014918186808,-0.12074794835789432,-1.7258692943152663,1.5870359038920763,0.08478612682723895,2.2672389993833404,0.8597257693570096,0.016294229330441935,-0.5323553332283967,-0.7155317980973355,0.7459093931850885,-0.7842622939081015,-0.37219848961093516,2.1539773900288672,-0.6468228743068464,0.29014722557938266,-0.18929860246142455,0.7686765614043631
| 3,376
|
Intrinsic pathway for apoptosis
| 8
| 19
| 2.273748
| 0.022981
|
P27348,Q9NR28,P63104,Q04917,P61981,P31946,Q07021,P62258
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
156,33,419,169,333,147,149,90
|
1919,156,974,1347,2870,516,147,3251,1758,333,90,419,1722,169,149,2983,2496,33,1828
|
-0.18929860246142455,1.5870359038920763,0.38136454893617105,0.13043670441630822,-0.8071772923198322,0.8369663760218362,1.609734331636171,-1.6338076191106943,-0.09790213373324297,1.1554242122572953,2.040674250545313,0.9734938954710396,-0.07505850905423944,1.5416337356516463,1.609734331636171,-0.9447186346692006,-0.5094688519400632,2.8329412732198165,-0.12074794835789432
| 3,376
|
ATPase, AAA-type, core [IPR003959]
| 16
| 31
| 2.272163
| 0.023077
|
P62191,P35249,O75351,P40937,O43933,P36776,P17980,Q9NVI7,P62195,Q8NBU5,Q9H078,P43686,Q15645,Q96TA2,Q8WVB6,P46459
|
Sequence
|
InterPro Domain
|
interpro_domain
|
474,778,596,416,578,729,642,933,365,845,566,304,420,908,846,583
|
1165,578,596,1597,642,778,1718,2665,1719,729,416,304,583,946,474,365,1391,420,1246,2809,2489,845,846,908,2346,566,933,1377,1907,1671,1164
|
0.2445261280106561,0.7459093931850885,0.7231402673093839,-0.00654070501984235,0.6775961200071496,0.5409161013840437,-0.07505850905423944,-0.6239246546713384,-0.07505850905423944,0.5864840833173061,0.9734938954710396,1.2008880747372999,0.7459093931850885,0.40416373461270877,0.8824832327508613,1.0872144454036603,0.10761247991580983,0.9734938954710396,0.19889667227848584,-0.7384395552892268,-0.5094688519400632,0.4953400811340294,0.4953400811340294,0.4497559749392965,-0.4179460858744323,0.7686765614043631,0.4269608745762918,0.13043670441630822,-0.1664461756216075,-0.029377801621022746,0.2673377183743358
| 3,376
|
Severe muscular hypotonia
| 10
| 29
| 2.269814
| 0.023219
|
P50542,P02545,Q9NWM8,Q9GZY8,O95831,O43933,P06753,Q8TD30,Q8TD16,P40855
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,218,557,273,7,578,146,60,161,562
|
3212,578,1861,7,218,146,1519,562,65,862,1011,2400,1173,600,1145,732,2900,2401,2482,1288,2533,161,60,2268,2745,2347,273,557,1903
|
-1.4498172605482251,0.7459093931850885,-0.1664461756216075,4.321881386246311,1.4053843934011567,1.609734331636171,0.039127008246021396,0.7686765614043631,2.2672389993833404,0.4725490417782299,0.35856331139810654,-0.4637028527189056,0.2445261280106561,0.7231402673093839,0.2673377183743358,0.5864840833173061,-0.830094721554977,-0.4637028527189056,-0.5094688519400632,0.17607879404889298,-0.5323553332283967,1.5870359038920763,2.3804595810299363,-0.37219848961093516,-0.6697234659246303,-0.4179460858744323,1.291793624694478,0.791441777572769,-0.1664461756216075
| 3,376
|
Myeloid leukocyte mediated immunity
| 6
| 18
| 2.268506
| 0.023298
|
P09601,Q99584,Q7Z434,Q12846,Q15833,P12429
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
70,138,202,265,84,180
|
2319,1474,2193,70,2120,180,945,265,84,2483,202,737,1155,138,2747,2961,2714,338
|
-0.4179460858744323,0.061957638500894446,-0.3493281113577081,2.2445899756334495,-0.30359415686543867,1.496224452836366,0.40416373461270877,1.291793624694478,2.063338225377154,-0.5094688519400632,1.4508080180236562,0.5864840833173061,0.2673377183743358,1.6551258973436702,-0.6697234659246303,-0.8988616809189766,-0.6468228743068464,1.1554242122572953
| 3,376
|
Positive regulation of dna biosynthetic process
| 17
| 29
| 2.259589
| 0.023847
|
P27361,P35249,P40227,P49368,P07900,P40937,Q15185,P48643,Q9BRT9,Q8WVB6,Q9BRX5,P40938,Q99832,P78371,Q96HR8,P08238,P50990
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
974,778,1107,446,663,416,843,860,48,846,1120,835,931,432,877,1073,623
|
1165,2852,1273,663,1073,1643,1239,1384,1753,974,1347,2011,778,1718,1107,416,835,860,446,623,1489,432,843,846,877,931,48,1120,1461
|
0.2445261280106561,-0.7842622939081015,0.17607879404889298,0.654821087209402,0.31295465596021727,-0.029377801621022746,0.19889667227848584,0.10761247991580983,-0.09790213373324297,0.38136454893617105,0.13043670441630822,-0.23501011839942096,0.5409161013840437,-0.07505850905423944,0.29014722557938266,0.9734938954710396,0.4953400811340294,0.4725490417782299,0.9279923914863851,0.7003691781398825,0.061957638500894446,0.9507440976385911,0.4953400811340294,0.4953400811340294,0.4725490417782299,0.4269608745762918,2.5162708123670816,0.29014722557938266,0.08478612682723895
| 3,376
|
Transmembrane transport
| 63
| 228
| 2.256181
| 0.024059
|
O60830,P07384,P12235,Q9UHG3,P00403,Q99595,O95831,O75964,Q9BSK2,Q8IWX8,P46934,Q96GC9,P50416,P31751,P46939,O75947,P13073,P21796,Q16762,Q9NS69,Q8N668,P61421,Q9C0H2,Q86VD7,O43707,Q8TB61,Q15629,Q9H2D1,Q9UI12,Q15388,Q9HAV7,Q6KCM7,Q04917,O00299,Q9Y696,P45880,P50542,Q9HC07,Q14847,O43933,O43865,P38435,Q9UDW1,P20674,Q8NE01,Q9UJZ1,P48047,Q9BQT8,Q9NVV0,Q8N4V1,Q93034,P24539,P62258,Q15041,P36543,Q8WWC4,Q9UBX3,P00846,Q13423,P31930,Q6P4Q7,O14745,P06576
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,128,129,135,254,6,7,8,9,652,11,389,517,516,646,394,395,20,408,22,538,279,27,160,529,288,35,36,559,164,555,551,169,546,573,56,65,207,585,578,577,331,79,199,81,611,461,215,349,86,606,344,90,477,598,356,360,99,354,232,108,614,122
|
1996,1474,546,2850,2355,2285,2113,614,1706,1383,1435,529,2115,2551,577,578,748,0,1438,1674,2193,1998,2431,1596,1861,938,1676,394,8,806,774,1864,807,7,2084,254,99,1796,1199,1920,1274,2323,2828,122,1341,128,687,3008,2118,916,1104,664,1832,857,1680,2120,943,129,2201,395,1168,1645,886,1313,2037,199,2038,2122,3141,20,1345,344,644,2802,2439,2293,1872,2556,1388,889,516,232,1756,2294,2557,975,598,331,1315,3263,1963,56,11,646,2043,461,751,1281,517,65,780,2250,920,862,1523,1877,2295,2366,1926,667,3264,1967,279,3028,90,1394,3029,2336,1688,1929,1573,169,1525,3124,2669,3085,1245,354,1209,1495,2604,585,477,2935,164,2785,35,2168,1018,2983,408,1499,1500,551,1363,2610,1578,108,1452,2404,2612,3114,1813,3295,160,2488,652,3335,3052,86,538,81,925,2709,288,2533,985,2376,356,1091,606,1664,389,1220,739,3135,1506,1986,3331,6,909,2537,2579,2842,215,1545,9,3352,2145,3101,27,3042,3372,36,3311,1548,1665,2275,2068,555,207,1900,994,932,2714,1737,22,2350,349,1124,360,79,1741,767,135,559,2424,611,720,3044,962,3156,1593,2353,1164,2318,573,2354
|
-0.23501011839942096,0.061957638500894446,0.791441777572769,-0.7842622939081015,-0.4408233191309774,-0.3950711452504818,-0.30359415686543867,0.7003691781398825,-0.07505850905423944,0.10761247991580983,0.08478612682723895,0.8142050472643398,-0.30359415686543867,-0.5552441461593581,0.7459093931850885,0.7459093931850885,0.5637010941850982,8.666912565323075,0.08478612682723895,-0.05221706733189361,-0.3493281113577081,-0.23501011839942096,-0.48658469438810514,-0.00654070501984235,-0.1664461756216075,0.40416373461270877,-0.05221706733189361,1.0189877874715023,4.186777541252852,0.5181290990123865,0.5409161013840437,-0.1664461756216075,0.5181290990123865,4.321881386246311,-0.2807305656763728,1.3145154214917698,1.9500014918186808,-0.12074794835789432,0.22171244811574498,-0.18929860246142455,0.17607879404889298,-0.4179460858744323,-0.7613497177385024,1.7458879968087067,0.13043670441630822,1.700510440366334,0.6320440740122428,-0.9905855228656107,-0.30359415686543867,0.4269608745762918,0.29014722557938266,0.654821087209402,-0.14359595996140015,0.4725490417782299,-0.05221706733189361,-0.30359415686543867,0.40416373461270877,1.700510440366334,-0.3493281113577081,1.0189877874715023,0.2445261280106561,-0.029377801621022746,0.4497559749392965,0.15325880693776223,-0.2578692219726256,1.4508080180236562,-0.2578692219726256,-0.30359415686543867,-1.2200715510997944,3.3751044359501514,0.13043670441630822,1.1326894914941044,0.6775961200071496,-0.7384395552892268,-0.48658469438810514,-0.3950711452504818,-0.1664461756216075,-0.5552441461593581,0.10761247991580983,0.4497559749392965,0.8369663760218362,1.382669872986797,-0.09790213373324297,-0.3950711452504818,-0.5552441461593581,0.38136454893617105,0.7231402673093839,1.1554242122572953,0.15325880693776223,-1.702849657699171,-0.21215324764925397,2.3804595810299363,3.8037153417241023,0.6775961200071496,-0.2578692219726256,0.9052387716538994,0.5637010941850982,0.17607879404889298,0.8369663760218362,2.2672389993833404,0.5409161013840437,-0.37219848961093516,0.4269608745762918,0.4725490417782299,0.039127008246021396,-0.1664461756216075,-0.3950711452504818,-0.4408233191309774,-0.18929860246142455,0.654821087209402,-1.702849657699171,-0.21215324764925397,1.2690699965758048,-1.0135227149606314,2.040674250545313,0.10761247991580983,-1.0135227149606314,-0.4179460858744323,-0.05221706733189361,-0.18929860246142455,0.016294229330441935,1.5416337356516463,0.039127008246021396,-1.1741538836336023,-0.6239246546713384,-1.105296684161769,0.19889667227848584,1.1099529042532705,0.22171244811574498,0.061957638500894446,-0.5781352986923748,0.7459093931850885,0.8824832327508613,-0.8759369071217561,1.5643357067698693,-0.7155317980973355,2.765109185211371,-0.3264600029423213,0.35856331139810654,-0.9447186346692006,0.9962417903147566,0.061957638500894446,0.061957638500894446,0.791441777572769,0.13043670441630822,-0.5781352986923748,0.016294229330441935,1.881979102274105,0.08478612682723895,-0.4637028527189056,-0.5781352986923748,-1.1511989198698822,-0.12074794835789432,-1.8640469790949206,1.5870359038920763,-0.5094688519400632,0.6775961200071496,-2.256127013938457,-1.0594046408731053,2.063338225377154,0.8142050472643398,2.108661146393929,0.4269608745762918,-0.6468228743068464,1.2463445321935245,-0.5323553332283967,0.38136454893617105,-0.4408233191309774,1.1099529042532705,0.31295465596021727,0.7231402673093839,-0.029377801621022746,1.0417318922140226,0.22171244811574498,0.5864840833173061,-1.1971114241452179,0.061957638500894446,-0.21215324764925397,-2.209954355282571,4.6369364917203,0.4497559749392965,-0.5323553332283967,-0.5552441461593581,-0.7613497177385024,1.4280971068172954,0.039127008246021396,4.119207289654426,-2.7880413064895926,-0.30359415686543867,-1.1282465232303278,2.9685637646665515,-1.036462417892556,-5.244320590828346,2.742495377855693,-1.9792747662426717,0.039127008246021396,-0.029377801621022746,-0.37219848961093516,-0.2578692219726256,0.791441777572769,1.4508080180236562,-0.1664461756216075,0.38136454893617105,0.4269608745762918,-0.6468228743068464,-0.07505850905423944,3.352531486014035,-0.4179460858744323,1.1326894914941044,0.29014722557938266,1.1099529042532705,2.1539773900288672,-0.07505850905423944,0.5637010941850982,1.6778190444254801,0.791441777572769,-0.4637028527189056,0.7231402673093839,0.6092650746483713,-1.036462417892556,0.40416373461270877,-1.2430342742645197,0.016294229330441935,-0.4179460858744323,0.2673377183743358,-0.3950711452504818,0.7686765614043631,-0.4179460858744323
| 3,376
|
centrosome
| 15
| 34
| 2.255529
| 0.0241
|
P27348,Q07866,P63104,P41208,O43237,Q10713,Q04917,P61981,Q13561,Q9Y6G9,Q9H0B6,P31946,O14745,P62258,P33176
|
Localization
|
OpenCell Localization
|
opencell_localization
|
156,535,419,471,639,550,169,333,242,574,608,147,614,90,256
|
614,639,1041,2798,1200,664,1645,886,156,147,256,1803,471,2631,2477,333,90,419,169,535,550,2130,753,242,2302,2401,952,3001,2790,2496,2497,2412,608,574
|
0.7003691781398825,0.6775961200071496,0.33576001581343007,-0.7384395552892268,0.22171244811574498,0.654821087209402,-0.029377801621022746,0.4497559749392965,1.5870359038920763,1.609734331636171,1.3145154214917698,-0.12074794835789432,0.8824832327508613,-0.6010287988405737,-0.5094688519400632,1.1554242122572953,2.040674250545313,0.9734938954710396,1.5416337356516463,0.8142050472643398,0.791441777572769,-0.30359415686543867,0.5637010941850982,1.359953540760634,-0.3950711452504818,-0.4637028527189056,0.40416373461270877,-0.9676508324618752,-0.7155317980973355,-0.5094688519400632,-0.5094688519400632,-0.4637028527189056,0.7231402673093839,0.7686765614043631
| 3,376
|
Areflexia
| 24
| 96
| 2.254733
| 0.02415
|
P12235,Q9NR77,O95831,O15269,Q8TB36,P06753,Q15149,O95140,Q8TD16,Q9Y281,O60313,Q969X5,P50542,O95721,Q9H6K4,O43933,Q6UWE0,Q9BQT8,O75477,Q96RL7,Q03001,Q15041,P02545,O00429
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
129,4,7,514,539,146,536,404,161,572,428,451,65,444,206,578,603,215,342,92,601,477,218,351
|
351,2892,2320,514,3212,1235,578,1595,428,1041,2286,1196,342,1862,404,2081,1679,444,7,218,1199,146,1201,1481,3224,129,1602,2086,1519,917,2665,1650,1170,1139,3263,2249,1653,65,780,2633,2981,1008,862,1567,1490,1568,946,1965,2093,2332,864,1688,1572,601,625,2900,1576,1355,2975,1495,2052,477,951,754,1497,536,2785,2482,2524,1617,1406,603,1153,3037,1695,539,161,1980,3167,905,451,2884,92,1371,1730,215,1419,2958,1665,206,4,1903,1743,572,2387,3022
|
1.1099529042532705,-0.830094721554977,-0.4179460858744323,0.8369663760218362,-1.4498172605482251,0.19889667227848584,0.7459093931850885,-0.00654070501984235,0.9507440976385911,0.33576001581343007,-0.3950711452504818,0.22171244811574498,1.1326894914941044,-0.1664461756216075,0.9962417903147566,-0.2807305656763728,-0.05221706733189361,0.9279923914863851,4.321881386246311,1.4053843934011567,0.22171244811574498,1.609734331636171,0.22171244811574498,0.061957638500894446,-1.4957984470366237,1.700510440366334,-0.00654070501984235,-0.2807305656763728,0.039127008246021396,0.4269608745762918,-0.6239246546713384,-0.029377801621022746,0.2445261280106561,0.2673377183743358,-1.702849657699171,-0.37219848961093516,-0.029377801621022746,2.2672389993833404,0.5409161013840437,-0.6010287988405737,-0.9447186346692006,0.35856331139810654,0.4725490417782299,0.016294229330441935,0.061957638500894446,0.016294229330441935,0.40416373461270877,-0.21215324764925397,-0.2807305656763728,-0.4179460858744323,0.4725490417782299,-0.05221706733189361,0.016294229330441935,0.7231402673093839,0.7003691781398825,-0.830094721554977,0.016294229330441935,0.13043670441630822,-0.9217889204720701,0.061957638500894446,-0.2578692219726256,0.8824832327508613,0.40416373461270877,0.5637010941850982,0.061957638500894446,0.8142050472643398,-0.7155317980973355,-0.5094688519400632,-0.5323553332283967,-0.00654070501984235,0.10761247991580983,0.7231402673093839,0.2673377183743358,-1.036462417892556,-0.05221706733189361,0.8142050472643398,1.5870359038920763,-0.21215324764925397,-1.288967548658644,0.4497559749392965,0.9279923914863851,-0.8071772923198322,2.040674250545313,0.13043670441630822,-0.07505850905423944,1.4280971068172954,0.10761247991580983,-0.8988616809189766,-0.029377801621022746,1.4508080180236562,5.109040668422138,-0.1664461756216075,-0.07505850905423944,0.7686765614043631,-0.4408233191309774,-0.9905855228656107
| 3,376
|
Regulation of pten stability and activity
| 11
| 44
| 2.248351
| 0.024554
|
P62191,P48556,P61289,P46934,Q9UNM6,P31751,P28066,Q92530,P62195,P43686,O00231
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
474,157,219,11,276,516,330,114,365,304,340
|
340,1433,1337,2850,1515,1305,1307,2155,642,1441,2324,1870,1387,1482,1871,330,2629,1648,2203,516,1719,304,11,157,2951,2667,1762,2561,2296,219,474,365,1391,1011,1208,1082,2605,895,114,2840,1544,1063,571,276
|
1.1326894914941044,0.08478612682723895,0.13043670441630822,-0.7842622939081015,0.039127008246021396,0.15325880693776223,0.15325880693776223,-0.3264600029423213,0.6775961200071496,0.08478612682723895,-0.4179460858744323,-0.1664461756216075,0.10761247991580983,0.061957638500894446,-0.1664461756216075,1.1554242122572953,-0.6010287988405737,-0.029377801621022746,-0.3493281113577081,0.8369663760218362,-0.07505850905423944,1.2008880747372999,3.8037153417241023,1.5870359038920763,-0.8988616809189766,-0.6239246546713384,-0.09790213373324297,-0.5552441461593581,-0.3950711452504818,1.4053843934011567,0.8824832327508613,1.0872144454036603,0.10761247991580983,0.35856331139810654,0.22171244811574498,0.31295465596021727,-0.5781352986923748,0.4497559749392965,1.8366222925568745,-0.7613497177385024,0.039127008246021396,0.33576001581343007,0.7686765614043631,1.291793624694478
| 3,376
|
Collagen formation
| 6
| 13
| 2.24806
| 0.024572
|
O75718,Q32P28,P13674,Q15149,Q03001,O15460
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
239,478,249,536,601,125
|
770,125,1916,239,1103,249,1314,1685,1611,601,536,478,1117
|
0.5409161013840437,1.7232000896678,-0.18929860246142455,1.359953540760634,0.29014722557938266,1.3372353918837696,0.15325880693776223,-0.05221706733189361,-0.00654070501984235,0.7231402673093839,0.8142050472643398,0.8824832327508613,0.29014722557938266
| 3,376
|
Response to oxygen levels
| 9
| 62
| 2.238698
| 0.025176
|
Q96A26,P02545,P00846,P09601,O95831,O75306,P00813,Q8N511,P30519
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,218,99,70,7,197,19,153,25
|
1514,770,529,936,197,2002,7,940,19,99,218,3286,3259,1919,1920,2967,1103,70,1680,1133,2662,1602,1754,1278,25,888,729,1315,1684,1758,1875,2045,3195,920,730,279,3011,1611,2731,2129,2402,1932,1497,2370,3320,1183,697,153,1154,1626,3167,1538,32,2577,1220,909,1422,2823,571,801,469,1335
|
0.039127008246021396,0.5409161013840437,0.8142050472643398,0.40416373461270877,1.4508080180236562,-0.23501011839942096,4.321881386246311,0.40416373461270877,3.3976759190434085,1.9500014918186808,1.4053843934011567,-1.8179762690089385,-1.6798328406028724,-0.18929860246142455,-0.18929860246142455,-0.9217889204720701,0.29014722557938266,2.2445899756334495,-0.05221706733189361,0.2673377183743358,-0.6239246546713384,-0.00654070501984235,-0.09790213373324297,0.17607879404889298,3.0363543565552815,0.4497559749392965,0.5864840833173061,0.15325880693776223,-0.05221706733189361,-0.09790213373324297,-0.1664461756216075,-0.2578692219726256,-1.3808656899217036,0.4269608745762918,0.5864840833173061,1.2690699965758048,-0.9905855228656107,-0.00654070501984235,-0.6697234659246303,-0.30359415686543867,-0.4637028527189056,-0.18929860246142455,0.061957638500894446,-0.4408233191309774,-2.071510292020483,0.2445261280106561,0.6320440740122428,1.609734331636171,0.2673377183743358,-0.00654070501984235,-1.288967548658644,0.039127008246021396,2.8555488697395974,-0.5552441461593581,0.22171244811574498,0.4497559749392965,0.10761247991580983,-0.7384395552892268,0.7686765614043631,0.5409161013840437,0.9052387716538994,0.15325880693776223
| 3,376
|
Ion transmembrane transport
| 51
| 167
| 2.231876
| 0.025623
|
P07384,P12235,Q9UHG3,P00403,Q96GC9,O75964,Q8IWX8,P46934,P46939,O75947,P25705,P13073,P21796,Q8N668,P61421,Q9C0H2,Q86VD7,O43707,Q8TB61,Q9UI12,Q9H2D1,P0DP25,Q6KCM7,P56385,Q04917,O00299,Q9Y696,P45880,Q9HC07,Q14847,O43865,Q9UDW1,P20674,P48047,Q9UJZ1,Q9BQT8,Q9NVV0,Q8N4V1,Q93034,P24539,P62258,Q15041,P36543,Q8WWC4,Q9UBX3,P00846,Q13423,P31930,Q6P4Q7,O14745,P06576
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,129,135,254,389,8,652,11,646,394,644,395,20,538,279,27,160,529,288,559,36,664,551,667,169,546,573,56,207,585,577,79,199,461,611,215,349,86,606,344,90,477,598,356,360,99,354,232,108,614,122
|
546,2850,2355,2285,614,1383,529,2115,2551,577,748,1438,1674,2193,1998,1596,1861,938,1676,394,8,774,1864,807,254,99,1199,1920,1274,2323,2828,122,1341,128,687,3008,2118,916,1104,664,1832,943,129,2201,395,1168,1645,886,1313,2037,199,2038,2122,3141,20,344,644,2802,2439,2293,2556,1388,889,232,2294,2557,975,598,1315,3263,1963,56,11,646,2043,461,780,2250,862,1523,1877,2295,2366,1926,667,279,3028,90,1394,3029,2336,1688,1929,169,3124,3085,1245,354,1209,1495,2604,585,477,2935,2785,2168,2983,1500,551,1578,108,1452,2404,3114,1813,160,652,3052,86,538,925,288,985,356,606,389,1220,3135,1986,909,2579,2842,215,1545,3352,27,3042,3372,36,3311,1665,2275,2068,207,1900,994,932,2714,2350,349,1124,360,79,767,135,559,2424,611,3044,962,3156,1593,2353,1164,2318,573,2354
|
0.791441777572769,-0.7842622939081015,-0.4408233191309774,-0.3950711452504818,0.7003691781398825,0.10761247991580983,0.8142050472643398,-0.30359415686543867,-0.5552441461593581,0.7459093931850885,0.5637010941850982,0.08478612682723895,-0.05221706733189361,-0.3493281113577081,-0.23501011839942096,-0.00654070501984235,-0.1664461756216075,0.40416373461270877,-0.05221706733189361,1.0189877874715023,4.186777541252852,0.5409161013840437,-0.1664461756216075,0.5181290990123865,1.3145154214917698,1.9500014918186808,0.22171244811574498,-0.18929860246142455,0.17607879404889298,-0.4179460858744323,-0.7613497177385024,1.7458879968087067,0.13043670441630822,1.700510440366334,0.6320440740122428,-0.9905855228656107,-0.30359415686543867,0.4269608745762918,0.29014722557938266,0.654821087209402,-0.14359595996140015,0.40416373461270877,1.700510440366334,-0.3493281113577081,1.0189877874715023,0.2445261280106561,-0.029377801621022746,0.4497559749392965,0.15325880693776223,-0.2578692219726256,1.4508080180236562,-0.2578692219726256,-0.30359415686543867,-1.2200715510997944,3.3751044359501514,1.1326894914941044,0.6775961200071496,-0.7384395552892268,-0.48658469438810514,-0.3950711452504818,-0.5552441461593581,0.10761247991580983,0.4497559749392965,1.382669872986797,-0.3950711452504818,-0.5552441461593581,0.38136454893617105,0.7231402673093839,0.15325880693776223,-1.702849657699171,-0.21215324764925397,2.3804595810299363,3.8037153417241023,0.6775961200071496,-0.2578692219726256,0.9052387716538994,0.5409161013840437,-0.37219848961093516,0.4725490417782299,0.039127008246021396,-0.1664461756216075,-0.3950711452504818,-0.4408233191309774,-0.18929860246142455,0.654821087209402,1.2690699965758048,-1.0135227149606314,2.040674250545313,0.10761247991580983,-1.0135227149606314,-0.4179460858744323,-0.05221706733189361,-0.18929860246142455,1.5416337356516463,-1.1741538836336023,-1.105296684161769,0.19889667227848584,1.1099529042532705,0.22171244811574498,0.061957638500894446,-0.5781352986923748,0.7459093931850885,0.8824832327508613,-0.8759369071217561,-0.7155317980973355,-0.3264600029423213,-0.9447186346692006,0.061957638500894446,0.791441777572769,0.016294229330441935,1.881979102274105,0.08478612682723895,-0.4637028527189056,-1.1511989198698822,-0.12074794835789432,1.5870359038920763,0.6775961200071496,-1.0594046408731053,2.063338225377154,0.8142050472643398,0.4269608745762918,1.2463445321935245,0.38136454893617105,1.1099529042532705,0.7231402673093839,1.0417318922140226,0.22171244811574498,-1.1971114241452179,-0.21215324764925397,0.4497559749392965,-0.5552441461593581,-0.7613497177385024,1.4280971068172954,0.039127008246021396,-2.7880413064895926,2.9685637646665515,-1.036462417892556,-5.244320590828346,2.742495377855693,-1.9792747662426717,-0.029377801621022746,-0.37219848961093516,-0.2578692219726256,1.4508080180236562,-0.1664461756216075,0.38136454893617105,0.4269608745762918,-0.6468228743068464,-0.4179460858744323,1.1326894914941044,0.29014722557938266,1.1099529042532705,2.1539773900288672,0.5637010941850982,1.6778190444254801,0.791441777572769,-0.4637028527189056,0.7231402673093839,-1.036462417892556,0.40416373461270877,-1.2430342742645197,0.016294229330441935,-0.4179460858744323,0.2673377183743358,-0.3950711452504818,0.7686765614043631,-0.4179460858744323
| 3,376
|
Proteasome accessory complex
| 7
| 22
| 2.231125
| 0.025673
|
P62191,P48556,P61289,Q9UNM6,P62195,P43686,O00231
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
474,157,219,276,365,304,340
|
340,1433,1337,1515,1307,642,1719,304,157,1762,2561,219,474,365,1391,1208,1082,895,980,1544,1063,276
|
1.1326894914941044,0.08478612682723895,0.13043670441630822,0.039127008246021396,0.15325880693776223,0.6775961200071496,-0.07505850905423944,1.2008880747372999,1.5870359038920763,-0.09790213373324297,-0.5552441461593581,1.4053843934011567,0.8824832327508613,1.0872144454036603,0.10761247991580983,0.22171244811574498,0.31295465596021727,0.4497559749392965,0.38136454893617105,0.039127008246021396,0.33576001581343007,1.291793624694478
| 3,376
|
Negative regulation of immune system process
| 23
| 50
| 2.22913
| 0.025805
|
Q9Y5A9,Q9Y4E8,P46108,P00813,P09429,P04439,P38646,Q9HCL2,P15311,Q7Z739,Q8WXW3,P04083,P14174,Q9UKG1,P09601,P10644,Q92990,Q13951,P17931,Q86UT6,Q99576,Q5JRA6,Q16539
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
912,402,645,19,776,145,919,175,292,435,54,686,318,720,70,459,605,869,725,1022,105,366,1018
|
2891,1233,1559,1310,19,686,145,776,70,459,2120,318,292,725,1313,1870,2629,1001,2781,2011,919,2829,1758,645,2205,2519,1353,2833,1245,869,2166,2132,1844,1018,366,435,1248,1022,54,605,2221,1984,105,175,2941,2382,720,1554,402,912
|
-0.830094721554977,0.19889667227848584,0.016294229330441935,0.15325880693776223,3.3976759190434085,0.6320440740122428,1.609734331636171,0.5409161013840437,2.2445899756334495,0.9052387716538994,-0.30359415686543867,1.1781570716463348,1.2236172265790646,0.5864840833173061,0.15325880693776223,-0.1664461756216075,-0.6010287988405737,0.35856331139810654,-0.7155317980973355,-0.23501011839942096,0.4269608745762918,-0.7613497177385024,-0.09790213373324297,0.6775961200071496,-0.3493281113577081,-0.5323553332283967,0.13043670441630822,-0.7613497177385024,0.19889667227848584,0.4725490417782299,-0.3264600029423213,-0.30359415686543867,-0.14359595996140015,0.35856331139810654,1.0872144454036603,0.9507440976385911,0.19889667227848584,0.35856331139810654,2.425736436209684,0.7231402673093839,-0.3493281113577081,-0.21215324764925397,1.9273290662444884,1.5416337356516463,-0.8759369071217561,-0.4408233191309774,0.6092650746483713,0.039127008246021396,1.0189877874715023,0.4497559749392965
| 3,376
|
Oxidoreductase complex
| 10
| 61
| 2.225442
| 0.026052
|
O43169,O43837,Q16718,P22695,P31930,Q9UDW1,O75306,O43676,Q9P0J0,P13674
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
37,196,233,44,232,79,197,21,88,249
|
2284,2355,615,37,2079,21,998,196,1998,197,805,303,661,1272,515,2798,2690,547,2799,1103,1921,916,2006,2660,2393,1833,249,2035,619,2693,1682,3280,44,2159,2246,2325,1755,2009,232,1138,2041,2697,2043,1925,1205,861,1686,1447,1932,233,1404,3098,1773,2142,759,2543,88,79,2717,1671,638
|
-0.3950711452504818,-0.4408233191309774,0.7003691781398825,2.6520244957361756,-0.2807305656763728,3.352531486014035,0.35856331139810654,1.4508080180236562,-0.23501011839942096,1.4508080180236562,0.5181290990123865,1.2008880747372999,0.654821087209402,0.17607879404889298,0.8369663760218362,-0.7384395552892268,-0.6468228743068464,0.791441777572769,-0.7384395552892268,0.29014722557938266,-0.18929860246142455,0.4269608745762918,-0.23501011839942096,-0.6239246546713384,-0.4637028527189056,-0.14359595996140015,1.3372353918837696,-0.2578692219726256,0.7003691781398825,-0.6468228743068464,-0.05221706733189361,-1.7949452375604908,2.561528394244356,-0.3264600029423213,-0.37219848961093516,-0.4179460858744323,-0.09790213373324297,-0.23501011839942096,1.382669872986797,0.2673377183743358,-0.2578692219726256,-0.6468228743068464,-0.2578692219726256,-0.18929860246142455,0.22171244811574498,0.4725490417782299,-0.05221706733189361,0.08478612682723895,-0.18929860246142455,1.382669872986797,0.10761247991580983,-1.1282465232303278,-0.09790213373324297,-0.30359415686543867,0.5637010941850982,-0.5323553332283967,2.063338225377154,2.1539773900288672,-0.6468228743068464,-0.029377801621022746,0.7003691781398825
| 3,376
|
Muscle system process
| 11
| 61
| 2.22447
| 0.026117
|
Q12792,P02545,P09493,P09601,P60660,P00813,Q9NVV0,Q86U42,P67936,P06753,Q13464
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
220,218,69,70,74,19,349,347,305,146,61
|
2591,1235,936,1860,2001,806,19,218,2198,1199,1920,2967,146,687,69,70,2471,664,1481,943,3179,3009,1168,1645,886,2037,3141,2293,1388,1684,646,1281,779,2091,431,893,74,3011,305,1394,1175,1574,732,220,2565,1245,346,61,1971,2834,1147,2402,1153,347,1538,2616,2064,2579,349,544,1336
|
-0.5781352986923748,0.19889667227848584,0.40416373461270877,-0.1664461756216075,-0.23501011839942096,0.5181290990123865,3.3976759190434085,1.4053843934011567,-0.3493281113577081,0.22171244811574498,-0.18929860246142455,-0.9217889204720701,1.609734331636171,0.6320440740122428,2.2445899756334495,2.2445899756334495,-0.5094688519400632,0.654821087209402,0.061957638500894446,0.40416373461270877,-1.334911326938496,-0.9905855228656107,0.2445261280106561,-0.029377801621022746,0.4497559749392965,-0.2578692219726256,-1.2200715510997944,-0.3950711452504818,0.10761247991580983,-0.05221706733189361,0.6775961200071496,0.17607879404889298,0.5409161013840437,-0.2807305656763728,0.9507440976385911,0.4497559749392965,2.1992869889805133,-0.9905855228656107,1.2008880747372999,0.10761247991580983,0.2445261280106561,0.016294229330441935,0.5864840833173061,1.4053843934011567,-0.5552441461593581,0.19889667227848584,1.1326894914941044,2.357818723202082,-0.21215324764925397,-0.7613497177385024,0.2673377183743358,-0.4637028527189056,0.2673377183743358,1.1326894914941044,0.039127008246021396,-0.5781352986923748,-0.2578692219726256,-0.5552441461593581,1.1326894914941044,0.8142050472643398,0.15325880693776223
| 3,376
|
Mitochondrial envelope
| 88
| 339
| 2.223407
| 0.026188
|
O60830,Q9Y2C4,Q99595,O95831,O75964,Q9BSK2,P50416,O96000,P21796,O43676,Q9NS69,Q8TB36,Q15149,Q9NZ45,Q8WY22,Q96A26,Q9NR28,Q9H2D1,O43169,Q13505,Q9HAV7,Q69YU5,Q6KCM7,Q10713,P22695,Q567V2,P03886,P45880,Q9H078,P09601,P36551,P12532,Q9UDW1,Q9H061,Q9P0J0,Q96RL7,O00264,P00846,Q92665,P04818,Q8NI60,O75880,Q9Y2R0,P06576,P12235,Q9BYD1,Q86VD7,Q15388,Q9HCL2,Q8N183,P14406,Q9BYN8,Q7Z434,P20674,O75306,Q9BQT8,P53701,Q6DKK2,Q8N4H5,Q16718,P31930,P22830,Q9BXK5,P00403,Q9GZY8,Q9NX63,Q9H4A6,O95168,O75431,P24539,Q8WWC4,Q9UBX3,Q6SZW1,Q13423,O15121,O00429,Q9BWH2,O75947,P13073,O95140,Q16540,O60313,Q92552,Q96EY7,P48047,Q9BRT2,Q16891,P52815
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,1,6,7,8,9,517,515,20,21,22,539,536,28,29,32,33,36,37,39,555,40,551,550,44,46,547,56,566,70,71,76,79,78,88,92,89,99,104,107,111,112,116,122,129,140,160,164,175,185,181,194,202,199,197,215,209,224,234,233,232,231,244,254,273,275,312,303,327,344,356,360,355,354,352,351,400,394,395,404,421,428,450,452,461,481,501,495
|
1382,89,351,2355,3346,3364,2285,1706,615,352,1914,2154,37,1309,1435,2079,21,998,2115,1235,428,1437,0,1674,829,1998,197,327,1596,805,2116,2657,1861,112,394,8,1597,806,404,303,661,774,1272,1864,1598,7,515,2084,2690,254,99,547,107,2323,122,2799,916,560,1561,70,664,1832,857,3225,129,2201,76,395,181,619,971,1645,2662,725,1134,2086,2693,199,20,1682,1799,44,231,2628,1345,344,644,2325,2473,2556,3294,1755,232,1756,1874,1486,1757,975,71,919,1170,1684,2697,56,2043,461,2929,2632,1925,517,1282,861,920,495,1964,862,209,2161,1568,1965,1926,667,1686,2367,670,1492,1446,1284,2982,2049,2441,599,2336,691,1174,1447,1929,2669,550,1176,1449,2670,1322,354,39,2879,2447,2402,1084,536,164,2785,1615,1843,421,2983,233,1404,501,1499,924,1884,46,2572,3291,1246,3098,3112,40,224,1770,551,1363,2609,1578,3155,355,1621,2021,3114,1813,3115,202,2530,1022,160,1887,1773,790,1977,2056,3052,1368,185,2918,234,3002,1369,2457,1412,845,925,111,2709,539,2533,3017,356,1091,1849,29,2142,450,104,2059,32,1939,2643,793,2176,759,1664,3069,2177,452,2615,2408,1851,1729,3135,92,908,760,1986,1628,6,909,2842,1255,215,1459,481,9,2345,1698,990,1420,3375,400,1373,244,1896,2939,140,2843,2582,677,194,1221,3351,273,78,566,36,1548,742,2583,312,1122,2275,1032,2068,2276,2792,555,1900,175,2501,2349,2069,820,1422,33,2714,1737,1424,22,1854,2350,1330,1123,933,2110,852,2543,2749,3235,275,2149,28,1947,2587,3072,88,2381,2070,1301,360,79,2923,880,2717,2424,611,2964,1671,962,1,1637,116,2622,2073,2824,2890,1827,1638,1828,3206,1430,1164,1472,3272,746,1856,2318,882,2910,638,1829
|
0.10761247991580983,2.040674250545313,1.1099529042532705,-0.4408233191309774,-2.487180179584193,-4.114766801780013,-0.3950711452504818,-0.07505850905423944,0.7003691781398825,1.1099529042532705,-0.18929860246142455,-0.3264600029423213,2.6520244957361756,0.15325880693776223,0.08478612682723895,-0.2807305656763728,3.352531486014035,0.35856331139810654,-0.30359415686543867,0.19889667227848584,0.9507440976385911,0.08478612682723895,8.666912565323075,-0.05221706733189361,0.4953400811340294,-0.23501011839942096,1.4508080180236562,1.1554242122572953,-0.00654070501984235,0.5181290990123865,-0.30359415686543867,-0.6239246546713384,-0.1664461756216075,1.8366222925568745,1.0189877874715023,4.186777541252852,-0.00654070501984235,0.5181290990123865,0.9962417903147566,1.2008880747372999,0.654821087209402,0.5409161013840437,0.17607879404889298,-0.1664461756216075,-0.00654070501984235,4.321881386246311,0.8369663760218362,-0.2807305656763728,-0.6468228743068464,1.3145154214917698,1.9500014918186808,0.791441777572769,1.9046549378235165,-0.4179460858744323,1.7458879968087067,-0.7384395552892268,0.4269608745762918,0.7686765614043631,0.016294229330441935,2.2445899756334495,0.654821087209402,-0.14359595996140015,0.4725490417782299,-1.4957984470366237,1.700510440366334,-0.3493281113577081,2.1766330180587605,1.0189877874715023,1.496224452836366,0.7003691781398825,0.38136454893617105,-0.029377801621022746,-0.6239246546713384,0.5864840833173061,0.2673377183743358,-0.2807305656763728,-0.6468228743068464,1.4508080180236562,3.3751044359501514,-0.05221706733189361,-0.12074794835789432,2.561528394244356,1.382669872986797,-0.6010287988405737,0.13043670441630822,1.1326894914941044,0.6775961200071496,-0.4179460858744323,-0.5094688519400632,-0.5552441461593581,-1.8640469790949206,-0.09790213373324297,1.382669872986797,-0.09790213373324297,-0.1664461756216075,0.061957638500894446,-0.09790213373324297,0.38136454893617105,2.2445899756334495,0.4269608745762918,0.2445261280106561,-0.05221706733189361,-0.6468228743068464,2.3804595810299363,-0.2578692219726256,0.9052387716538994,-0.8759369071217561,-0.6010287988405737,-0.18929860246142455,0.8369663760218362,0.17607879404889298,0.4725490417782299,0.4269608745762918,0.8597257693570096,-0.21215324764925397,0.4725490417782299,1.4280971068172954,-0.3264600029423213,0.016294229330441935,-0.21215324764925397,-0.18929860246142455,0.654821087209402,-0.05221706733189361,-0.4408233191309774,0.654821087209402,0.061957638500894446,0.08478612682723895,0.17607879404889298,-0.9447186346692006,-0.2578692219726256,-0.48658469438810514,0.7231402673093839,-0.4179460858744323,0.6320440740122428,0.2445261280106561,0.08478612682723895,-0.18929860246142455,-0.6239246546713384,0.791441777572769,0.2445261280106561,0.08478612682723895,-0.6239246546713384,0.15325880693776223,1.1099529042532705,2.629402843859662,-0.8071772923198322,-0.48658469438810514,-0.4637028527189056,0.31295465596021727,0.8142050472643398,1.5643357067698693,-0.7155317980973355,-0.00654070501984235,-0.14359595996140015,0.9734938954710396,-0.9447186346692006,1.382669872986797,0.10761247991580983,0.8597257693570096,0.061957638500894446,0.4269608745762918,-0.1664461756216075,2.5162708123670816,-0.5552441461593581,-1.8410101788328443,0.19889667227848584,-1.1282465232303278,-1.1511989198698822,2.6067796121171485,1.4053843934011567,-0.09790213373324297,0.791441777572769,0.13043670441630822,-0.5781352986923748,0.016294229330441935,-1.2430342742645197,1.1099529042532705,-0.00654070501984235,-0.23501011839942096,-1.1511989198698822,-0.12074794835789432,-1.1511989198698822,1.4508080180236562,-0.5323553332283967,0.35856331139810654,1.5870359038920763,-0.1664461756216075,-0.09790213373324297,0.5409161013840437,-0.21215324764925397,-0.2578692219726256,-1.0594046408731053,0.13043670441630822,1.496224452836366,-0.8530145902549154,1.382669872986797,-0.9676508324618752,0.13043670441630822,-0.48658469438810514,0.10761247991580983,0.4953400811340294,0.4269608745762918,1.859301555293337,-0.6468228743068464,0.8142050472643398,-0.5323553332283967,-0.9905855228656107,1.1099529042532705,0.31295465596021727,-0.14359595996140015,2.9233624102559466,-0.30359415686543867,0.9279923914863851,1.9273290662444884,-0.2578692219726256,2.8555488697395974,-0.18929860246142455,-0.6010287988405737,0.5409161013840437,-0.3264600029423213,0.5637010941850982,-0.029377801621022746,-1.082349393180815,-0.3264600029423213,0.9279923914863851,-0.5781352986923748,-0.4637028527189056,-0.14359595996140015,-0.07505850905423944,-1.1971114241452179,2.040674250545313,0.4497559749392965,0.5637010941850982,-0.21215324764925397,-0.00654070501984235,4.6369364917203,0.4497559749392965,-0.7613497177385024,0.19889667227848584,1.4280971068172954,0.08478612682723895,0.8824832327508613,4.119207289654426,-0.4179460858744323,-0.05221706733189361,0.38136454893617105,0.10761247991580983,-6.700585270484291,1.0189877874715023,0.13043670441630822,1.359953540760634,-0.1664461756216075,-0.8759369071217561,1.6551258973436702,-0.7613497177385024,-0.5552441461593581,0.654821087209402,1.4735171317837568,0.22171244811574498,-2.741717544462647,1.291793624694478,2.1539773900288672,0.7686765614043631,2.742495377855693,0.039127008246021396,0.5864840833173061,-0.5552441461593581,1.2008880747372999,0.29014722557938266,-0.37219848961093516,0.35856331139810654,-0.2578692219726256,-0.37219848961093516,-0.7155317980973355,0.791441777572769,-0.1664461756216075,1.5416337356516463,-0.5094688519400632,-0.4179460858744323,-0.2578692219726256,0.5181290990123865,0.10761247991580983,2.8329412732198165,-0.6468228743068464,-0.07505850905423944,0.10761247991580983,3.352531486014035,-0.14359595996140015,-0.4179460858744323,0.15325880693776223,0.29014722557938266,0.4269608745762918,-0.2807305656763728,0.4953400811340294,-0.5323553332283967,-0.6697234659246303,-1.518793113952308,1.291793624694478,-0.30359415686543867,2.9685637646665515,-0.18929860246142455,-0.5552441461593581,-1.082349393180815,2.063338225377154,-0.4408233191309774,-0.2578692219726256,0.17607879404889298,1.1099529042532705,2.1539773900288672,-0.8530145902549154,0.4725490417782299,-0.6468228743068464,-0.4637028527189056,0.7231402673093839,-0.8988616809189766,-0.029377801621022746,0.40416373461270877,8.02000511706989,-0.00654070501984235,1.8366222925568745,-0.5781352986923748,-0.2578692219726256,-0.7384395552892268,-0.8071772923198322,-0.12074794835789432,-0.00654070501984235,-0.12074794835789432,-1.403846866269295,0.10761247991580983,0.2673377183743358,0.08478612682723895,-1.7258692943152663,0.5864840833173061,-0.14359595996140015,-0.3950711452504818,0.4725490417782299,-0.830094721554977,0.7003691781398825,-0.12074794835789432
| 3,376
|
Regulation of protein catabolic process
| 39
| 125
| 2.215089
| 0.026754
|
P46934,Q9H2J4,P17980,Q13190,P14735,P51572,Q8N668,Q05397,P26038,Q04323,P07900,Q9UL15,P15311,Q96HY6,Q8IXJ6,Q9UNE7,P24941,O95816,P43686,Q13464,P46459,Q9UNN5,P49069,O94874,Q13596,O75150,Q4ZIN3,P54727,Q96QK1,Q9P0J0,Q92990,Q9Y4X5,P62191,P61289,Q92530,P62195,P49841,P35241,Q96JB5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
11,798,642,150,641,781,538,534,283,284,663,165,292,311,697,571,808,178,304,61,583,591,689,443,713,709,464,462,87,88,605,745,474,219,114,365,364,250,124
|
2776,2850,1515,2151,2320,2076,2390,2154,1234,1307,1100,1830,1129,804,709,2358,2155,443,2002,2392,178,1709,1796,1341,663,1073,1480,1562,3178,641,292,1645,886,642,1441,3141,808,283,1486,250,1719,304,1924,1806,583,3187,11,1443,2631,689,1281,364,2981,781,2477,1351,462,946,1609,1524,219,2930,474,365,1391,2804,2972,2635,284,1207,534,1145,1208,3124,2207,150,1082,61,713,2252,2165,2606,2481,1882,896,464,1408,2708,697,2102,538,1847,114,1156,605,1893,311,1984,124,2270,87,1544,1986,1823,798,2585,2648,3300,2503,2823,88,1667,1591,1509,3168,2426,165,1063,2236,571,591,745,2317,913,2239
|
-0.7155317980973355,-0.7842622939081015,0.039127008246021396,-0.3264600029423213,-0.4179460858744323,-0.2807305656763728,-0.4637028527189056,-0.3264600029423213,0.19889667227848584,0.15325880693776223,0.29014722557938266,-0.14359595996140015,0.2673377183743358,0.5181290990123865,0.6092650746483713,-0.4408233191309774,-0.3264600029423213,0.9279923914863851,-0.23501011839942096,-0.4637028527189056,1.496224452836366,-0.07505850905423944,-0.12074794835789432,0.13043670441630822,0.654821087209402,0.31295465596021727,0.061957638500894446,0.016294229330441935,-1.334911326938496,0.6775961200071496,1.2236172265790646,-0.029377801621022746,0.4497559749392965,0.6775961200071496,0.08478612682723895,-1.2200715510997944,0.5181290990123865,1.2463445321935245,0.061957638500894446,1.3372353918837696,-0.07505850905423944,1.2008880747372999,-0.18929860246142455,-0.12074794835789432,0.7459093931850885,-1.3578871802431933,3.8037153417241023,0.08478612682723895,-0.6010287988405737,0.6320440740122428,0.17607879404889298,1.0872144454036603,-0.9447186346692006,0.5409161013840437,-0.5094688519400632,0.13043670441630822,0.9052387716538994,0.40416373461270877,-0.00654070501984235,0.039127008246021396,1.4053843934011567,-0.8759369071217561,0.8824832327508613,1.0872144454036603,0.10761247991580983,-0.7384395552892268,-0.9217889204720701,-0.6010287988405737,1.2463445321935245,0.22171244811574498,0.8142050472643398,0.2673377183743358,0.22171244811574498,-1.1741538836336023,-0.3493281113577081,1.609734331636171,0.31295465596021727,2.357818723202082,0.6092650746483713,-0.37219848961093516,-0.3264600029423213,-0.5781352986923748,-0.5094688519400632,-0.1664461756216075,0.4497559749392965,0.9052387716538994,0.10761247991580983,-0.6468228743068464,0.6320440740122428,-0.2807305656763728,0.8142050472643398,-0.14359595996140015,1.8366222925568745,0.2673377183743358,0.7231402673093839,-0.1664461756216075,1.2008880747372999,-0.21215324764925397,1.7458879968087067,-0.37219848961093516,2.063338225377154,0.039127008246021396,-0.21215324764925397,-0.12074794835789432,0.5409161013840437,-0.5552441461593581,-0.6010287988405737,-1.8870866819578753,-0.5094688519400632,-0.7384395552892268,2.063338225377154,-0.029377801621022746,0.016294229330441935,0.061957638500894446,-1.288967548658644,-0.4637028527189056,1.5643357067698693,0.33576001581343007,-0.3493281113577081,0.7686765614043631,0.7459093931850885,0.5864840833173061,-0.3950711452504818,0.4497559749392965,-0.3493281113577081
| 3,376
|
Negative regulation of protein polymerization
| 6
| 25
| 2.211864
| 0.026976
|
Q13813,P16949,Q12792,P47755,P52907,P45880
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
221,34,220,167,113,56
|
1099,1310,3080,34,250,2040,712,56,167,1318,113,893,533,1012,220,2566,221,813,952,1247,1629,2958,702,544,1740
|
0.29014722557938266,0.15325880693776223,-1.105296684161769,2.765109185211371,1.3372353918837696,-0.2578692219726256,0.6092650746483713,2.3804595810299363,1.5416337356516463,0.15325880693776223,1.8366222925568745,0.4497559749392965,0.8142050472643398,0.35856331139810654,1.4053843934011567,-0.5552441461593581,1.4053843934011567,0.5181290990123865,0.40416373461270877,0.19889667227848584,-0.00654070501984235,-0.8988616809189766,0.6320440740122428,0.8142050472643398,-0.07505850905423944
| 3,376
|
Inositol lipid mediated signaling
| 9
| 20
| 2.209442
| 0.027144
|
Q53EZ4,Q969H8,Q10713,P46934,P15311,Q9NV70,Q07021,O14745,Q05397
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
223,588,550,11,292,245,149,614,534
|
1382,2591,614,2154,1197,292,11,1207,534,149,550,2402,223,697,1024,588,2577,245,2823,1301
|
0.10761247991580983,-0.5781352986923748,0.7003691781398825,-0.3264600029423213,0.22171244811574498,1.2236172265790646,3.8037153417241023,0.22171244811574498,0.8142050472643398,1.609734331636171,0.791441777572769,-0.4637028527189056,1.4053843934011567,0.6320440740122428,0.35856331139810654,0.7459093931850885,-0.5552441461593581,1.359953540760634,-0.7384395552892268,0.17607879404889298
| 3,376
|
Process utilizing autophagic mechanism
| 58
| 169
| 2.207064
| 0.02731
|
P07384,Q9ULC3,P12235,Q9BXS4,Q9NT62,Q96GC9,Q8IYI6,A5D8V6,P46934,Q9BWH2,Q969Q5,Q9Y487,O15269,P78344,P21796,Q9H0U4,Q9H9H4,P61421,O95140,Q9NP79,Q9NZ45,Q9UI12,P07900,Q9Y5K8,Q08379,Q96HY6,Q8IXJ6,Q9UNE7,Q96EP0,Q9UQN3,Q9Y5X3,Q9Y6I9,Q13464,P08754,P09601,Q9UNH7,O95721,O94874,P61960,Q6UWE0,Q9H267,Q96QK1,Q96RL7,P36543,O75351,O43633,Q8WUH2,Q9HD42,O00429,Q9UID3,Q9NV70,Q86UE4,Q93050,Q16543,P49841,O95817,Q9BRG1,Q9UPT5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,659,129,391,656,389,653,513,11,400,13,801,514,785,20,541,409,279,404,679,28,559,663,440,293,311,697,571,310,704,441,195,61,445,70,338,444,443,200,603,741,87,92,598,596,594,628,633,351,768,245,626,369,500,364,618,761,384
|
513,1382,2509,351,2591,2076,803,1913,514,1232,3283,2242,1309,594,596,2358,2000,938,443,404,444,618,1796,2895,1919,2323,1642,128,3268,663,1480,445,776,70,3178,1797,129,1168,1645,886,1441,1563,2694,2038,2122,20,974,2439,3294,598,1315,3251,1684,1758,1963,11,1281,364,2012,2981,945,920,1566,946,1609,2368,279,200,1206,1839,785,1688,1173,1840,1145,2669,293,2129,3359,61,1355,2165,1147,2402,2901,2019,2674,500,1181,2608,1771,1659,603,2737,2708,626,1249,697,653,3002,1695,2174,628,1154,1252,369,13,1253,1504,2577,310,389,2408,311,87,92,1986,2767,909,2106,761,400,391,1374,541,741,1631,1057,2886,409,633,1784,679,1422,2648,656,245,3088,3353,28,1947,2421,1226,2025,1855,1667,559,768,1591,659,1907,571,338,3293,384,704,1267,823,2029,2890,1746,3091,801,2590,1950,440,441,2389,195
|
0.8369663760218362,0.10761247991580983,-0.5323553332283967,1.1099529042532705,-0.5781352986923748,-0.2807305656763728,0.5181290990123865,-0.18929860246142455,0.8369663760218362,0.19889667227848584,-1.8179762690089385,-0.37219848961093516,0.15325880693776223,0.7231402673093839,0.7231402673093839,-0.4408233191309774,-0.23501011839942096,0.40416373461270877,0.9279923914863851,0.9962417903147566,0.9279923914863851,0.7003691781398825,-0.12074794835789432,-0.830094721554977,-0.18929860246142455,-0.4179460858744323,-0.029377801621022746,1.700510440366334,-1.7258692943152663,0.654821087209402,0.061957638500894446,0.9279923914863851,0.5409161013840437,2.2445899756334495,-1.334911326938496,-0.12074794835789432,1.700510440366334,0.2445261280106561,-0.029377801621022746,0.4497559749392965,0.08478612682723895,0.016294229330441935,-0.6468228743068464,-0.2578692219726256,-0.30359415686543867,3.3751044359501514,0.38136454893617105,-0.48658469438810514,-1.8640469790949206,0.7231402673093839,0.15325880693776223,-1.6338076191106943,-0.05221706733189361,-0.09790213373324297,-0.21215324764925397,3.8037153417241023,0.17607879404889298,1.0872144454036603,-0.23501011839942096,-0.9447186346692006,0.40416373461270877,0.4269608745762918,0.016294229330441935,0.40416373461270877,-0.00654070501984235,-0.4408233191309774,1.2690699965758048,1.4508080180236562,0.22171244811574498,-0.14359595996140015,0.5409161013840437,-0.05221706733189361,0.2445261280106561,-0.14359595996140015,0.2673377183743358,-0.6239246546713384,1.2236172265790646,-0.30359415686543867,-3.135924328813233,2.357818723202082,0.13043670441630822,-0.3264600029423213,0.2673377183743358,-0.4637028527189056,-0.830094721554977,-0.23501011839942096,-0.6239246546713384,0.8597257693570096,0.2445261280106561,-0.5781352986923748,-0.09790213373324297,-0.029377801621022746,0.7231402673093839,-0.6697234659246303,-0.6468228743068464,0.7003691781398825,0.19889667227848584,0.6320440740122428,0.6775961200071496,-0.9676508324618752,-0.05221706733189361,-0.3264600029423213,0.7003691781398825,0.2673377183743358,0.19889667227848584,1.0872144454036603,3.5556354942395423,0.19889667227848584,0.061957638500894446,-0.5552441461593581,1.2008880747372999,1.0417318922140226,-0.4637028527189056,1.2008880747372999,2.063338225377154,2.040674250545313,-0.21215324764925397,-0.6926264377581445,0.4497559749392965,-0.2807305656763728,0.5637010941850982,1.0189877874715023,1.0417318922140226,0.13043670441630822,0.8142050472643398,0.5864840833173061,-0.00654070501984235,0.33576001581343007,-0.8071772923198322,0.9962417903147566,0.7003691781398825,-0.09790213373324297,0.654821087209402,0.10761247991580983,-0.6010287988405737,0.6775961200071496,1.359953540760634,-1.105296684161769,-2.8343790211123925,2.9685637646665515,-0.18929860246142455,-0.4637028527189056,0.22171244811574498,-0.23501011839942096,-0.14359595996140015,-0.029377801621022746,0.791441777572769,0.5637010941850982,0.016294229330441935,0.6775961200071496,-0.1664461756216075,0.7686765614043631,1.1554242122572953,-1.8410101788328443,1.0644741097862722,0.6320440740122428,0.19889667227848584,0.5181290990123865,-0.23501011839942096,-0.8071772923198322,-0.07505850905423944,-1.105296684161769,0.5409161013840437,-0.5552441461593581,-0.18929860246142455,0.9507440976385911,0.9507440976385911,-0.4408233191309774,1.4735171317837568
| 3,376
|
Rhobtb gtpase cycle
| 11
| 30
| 2.200665
| 0.02776
|
Q5VTR2,Q16643,Q12792,O43396,Q9BT78,Q16543,P78371,P12814,Q13464,P61201,P08670
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
259,448,220,412,216,500,432,248,61,377,63
|
412,936,663,1342,1073,63,248,1962,1107,377,1392,432,220,1081,61,1323,2131,500,448,259,3160,3209,1726,3018,1780,2839,931,216,544,2588
|
0.9734938954710396,0.40416373461270877,0.654821087209402,0.13043670441630822,0.31295465596021727,2.312532127633527,1.3372353918837696,-0.21215324764925397,0.29014722557938266,1.0644741097862722,0.10761247991580983,0.9507440976385911,1.4053843934011567,0.31295465596021727,2.357818723202082,0.15325880693776223,-0.30359415686543867,0.8597257693570096,0.9279923914863851,1.3145154214917698,-1.2659996034795133,-1.426830719660142,-0.07505850905423944,-0.9905855228656107,-0.09790213373324297,-0.7613497177385024,0.4269608745762918,1.4280971068172954,0.8142050472643398,-0.5552441461593581
| 3,376
|
Regulation of cellular protein catabolic process
| 32
| 90
| 2.20059
| 0.027765
|
Q9H2J4,P17980,P51572,Q8N668,Q05397,P26038,Q04323,P07900,Q9UL15,P15311,Q96HY6,Q8IXJ6,Q9UNE7,P24941,O95816,P43686,Q9UNN5,P49069,O94874,O75150,Q4ZIN3,P54727,Q96QK1,Q92990,Q9Y4X5,P62191,P61289,Q92530,P62195,P49841,P35241,Q96JB5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
798,642,781,538,534,283,284,663,165,292,311,697,571,808,178,304,591,689,443,709,464,462,87,605,745,474,219,114,365,364,250,124
|
2776,1515,2151,2320,2390,2154,1234,1100,804,709,2155,443,2002,2392,178,1796,1341,663,1073,1562,292,1645,886,642,1441,808,283,250,1719,304,1924,1806,3187,1443,2631,689,1281,364,781,2477,1351,462,946,1609,1524,219,2930,474,365,1391,2804,2972,2635,284,1207,534,1208,3124,2207,2165,2606,464,1408,697,2102,538,114,1156,605,1893,311,124,2270,87,1986,1823,798,2648,2503,2823,1667,1591,165,1063,2236,571,591,745,2317,913
|
-0.7155317980973355,0.039127008246021396,-0.3264600029423213,-0.4179460858744323,-0.4637028527189056,-0.3264600029423213,0.19889667227848584,0.29014722557938266,0.5181290990123865,0.6092650746483713,-0.3264600029423213,0.9279923914863851,-0.23501011839942096,-0.4637028527189056,1.496224452836366,-0.12074794835789432,0.13043670441630822,0.654821087209402,0.31295465596021727,0.016294229330441935,1.2236172265790646,-0.029377801621022746,0.4497559749392965,0.6775961200071496,0.08478612682723895,0.5181290990123865,1.2463445321935245,1.3372353918837696,-0.07505850905423944,1.2008880747372999,-0.18929860246142455,-0.12074794835789432,-1.3578871802431933,0.08478612682723895,-0.6010287988405737,0.6320440740122428,0.17607879404889298,1.0872144454036603,0.5409161013840437,-0.5094688519400632,0.13043670441630822,0.9052387716538994,0.40416373461270877,-0.00654070501984235,0.039127008246021396,1.4053843934011567,-0.8759369071217561,0.8824832327508613,1.0872144454036603,0.10761247991580983,-0.7384395552892268,-0.9217889204720701,-0.6010287988405737,1.2463445321935245,0.22171244811574498,0.8142050472643398,0.22171244811574498,-1.1741538836336023,-0.3493281113577081,-0.3264600029423213,-0.5781352986923748,0.9052387716538994,0.10761247991580983,0.6320440740122428,-0.2807305656763728,0.8142050472643398,1.8366222925568745,0.2673377183743358,0.7231402673093839,-0.1664461756216075,1.2008880747372999,1.7458879968087067,-0.37219848961093516,2.063338225377154,-0.21215324764925397,-0.12074794835789432,0.5409161013840437,-0.6010287988405737,-0.5094688519400632,-0.7384395552892268,-0.029377801621022746,0.016294229330441935,1.5643357067698693,0.33576001581343007,-0.3493281113577081,0.7686765614043631,0.7459093931850885,0.5864840833173061,-0.3950711452504818,0.4497559749392965
| 3,376
|
Secretion
| 62
| 164
| 2.198469
| 0.027916
|
P61201,P00403,Q8IYI6,Q99584,P50416,P54920,Q12846,P00813,P08237,Q9NZ43,P20337,Q13505,P0DP25,Q9Y2D4,P15311,P55327,Q13153,Q9H4A6,Q9Y5X3,Q86YV9,Q86V21,Q8N183,Q16822,P12429,Q7Z7E8,P04083,Q15019,P46459,P14174,P09601,Q9UNH7,P35580,O95721,Q9BRK5,Q96KC8,P07741,O43760,Q9UBV2,Q15833,Q9NVV0,Q96QK1,Q32P28,Q9H7Z7,Q9BRT2,Q68EM7,Q8N5M9,Q13277,Q16836,O75351,O43633,Q9UPT5,Q96PC5,O00429,Q08209,Q9NV70,P49841,Q5JRA6,P49755,O14745,Q9HCU5,Q08752,O15126
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
377,254,653,138,517,141,265,19,775,290,532,39,664,824,292,168,294,312,441,696,695,185,308,180,844,686,841,583,318,70,338,582,444,75,467,329,707,609,84,349,87,478,743,481,479,737,475,735,596,594,384,102,351,732,245,364,366,751,614,383,752,486
|
2319,1474,1337,2284,351,2591,1191,2151,3075,614,2320,1193,2076,486,1383,2550,594,1071,707,1436,1437,914,1750,596,2627,1864,1598,444,2594,254,19,1709,686,1000,329,775,70,664,2007,3248,2120,3350,180,1867,318,292,2779,1168,1834,532,2694,1714,2123,2439,2440,1716,1388,1074,582,2294,1045,1170,1140,583,751,364,517,976,2981,2634,2598,945,920,2755,2478,1523,141,2366,168,3152,2368,1654,377,3347,1206,1688,1525,3124,732,752,2015,265,948,2129,294,475,39,1971,2166,841,2019,2935,2168,84,2483,1844,308,735,896,478,1529,366,2485,479,1771,3322,2612,3295,1935,3001,844,695,696,653,185,737,925,902,2265,1892,1252,1294,467,1818,102,87,1986,138,2106,75,481,1665,312,743,383,2714,245,3088,349,290,1226,1376,609,3341,2588,1907,338,881,384,824,1746,853,441,2240
|
-0.4179460858744323,0.061957638500894446,0.13043670441630822,-0.3950711452504818,1.1099529042532705,-0.5781352986923748,0.22171244811574498,-0.3264600029423213,-1.105296684161769,0.7003691781398825,-0.4179460858744323,0.22171244811574498,-0.2807305656763728,0.8597257693570096,0.10761247991580983,-0.5552441461593581,0.7231402673093839,0.31295465596021727,0.6092650746483713,0.08478612682723895,0.08478612682723895,0.4269608745762918,-0.09790213373324297,0.7231402673093839,-0.6010287988405737,-0.1664461756216075,-0.00654070501984235,0.9279923914863851,-0.5781352986923748,1.3145154214917698,3.3976759190434085,-0.07505850905423944,0.6320440740122428,0.35856331139810654,1.1554242122572953,0.5409161013840437,2.2445899756334495,0.654821087209402,-0.23501011839942096,-1.6107991920138482,-0.30359415686543867,-2.672257759321327,1.496224452836366,-0.1664461756216075,1.1781570716463348,1.2236172265790646,-0.7155317980973355,0.2445261280106561,-0.14359595996140015,0.8142050472643398,-0.6468228743068464,-0.07505850905423944,-0.30359415686543867,-0.48658469438810514,-0.48658469438810514,-0.07505850905423944,0.10761247991580983,0.31295465596021727,0.7459093931850885,-0.3950711452504818,0.33576001581343007,0.2445261280106561,0.2673377183743358,0.7459093931850885,0.5637010941850982,1.0872144454036603,0.8369663760218362,0.38136454893617105,-0.9447186346692006,-0.6010287988405737,-0.5781352986923748,0.40416373461270877,0.4269608745762918,-0.6926264377581445,-0.5094688519400632,0.039127008246021396,1.632430994596424,-0.4408233191309774,1.5416337356516463,-1.2430342742645197,-0.4408233191309774,-0.029377801621022746,1.0644741097862722,-2.556559283303169,0.22171244811574498,-0.05221706733189361,0.039127008246021396,-1.1741538836336023,0.5864840833173061,0.5637010941850982,-0.23501011839942096,1.291793624694478,0.40416373461270877,-0.30359415686543867,1.2236172265790646,0.8824832327508613,2.629402843859662,-0.21215324764925397,-0.3264600029423213,0.4953400811340294,-0.23501011839942096,-0.8759369071217561,-0.3264600029423213,2.063338225377154,-0.5094688519400632,-0.14359595996140015,1.2008880747372999,0.5864840833173061,0.4497559749392965,0.8824832327508613,0.039127008246021396,1.0872144454036603,-0.5094688519400632,0.8824832327508613,-0.09790213373324297,-2.117646103480084,-0.5781352986923748,-1.8640469790949206,-0.18929860246142455,-0.9676508324618752,0.4953400811340294,0.6320440740122428,0.6320440740122428,0.6775961200071496,1.496224452836366,0.5864840833173061,0.4269608745762918,0.4497559749392965,-0.37219848961093516,-0.1664461756216075,0.19889667227848584,0.17607879404889298,0.9052387716538994,-0.12074794835789432,1.9500014918186808,2.063338225377154,-0.21215324764925397,1.6551258973436702,-0.2807305656763728,2.1992869889805133,0.8824832327508613,-0.029377801621022746,1.2008880747372999,0.5864840833173061,1.0644741097862722,-0.6468228743068464,1.359953540760634,-1.105296684161769,1.1326894914941044,1.2463445321935245,0.22171244811574498,0.13043670441630822,0.7231402673093839,-2.3023121765421344,-0.5552441461593581,-0.1664461756216075,1.1554242122572953,0.4725490417782299,1.0644741097862722,0.5181290990123865,-0.07505850905423944,0.4953400811340294,0.9507440976385911,-0.3493281113577081
| 3,376
|
Retrograde transport endosome to golgi
| 12
| 38
| 2.189157
| 0.028585
|
Q5VIR6,O60749,P49257,Q9UNH7,Q14203,O60499,Q13190,O43752,O15260,Q96QK1,Q8IUD2,Q8NBN3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
423,253,257,338,334,12,150,326,82,87,381,225
|
82,2550,326,855,1129,12,253,2000,3309,579,2438,3132,257,2981,2634,2755,1173,150,713,334,2483,1529,2450,423,381,1625,225,1778,1893,87,2861,2225,1469,2025,768,3168,338,441
|
2.086000522614319,-0.5552441461593581,1.1554242122572953,0.4725490417782299,0.2673377183743358,3.713524418514359,1.3145154214917698,-0.23501011839942096,-1.9792747662426717,0.7459093931850885,-0.48658469438810514,-1.1971114241452179,1.3145154214917698,-0.9447186346692006,-0.6010287988405737,-0.6926264377581445,0.2445261280106561,1.609734331636171,0.6092650746483713,1.1554242122572953,-0.5094688519400632,0.039127008246021396,-0.48658469438810514,0.9734938954710396,1.0644741097862722,-0.00654070501984235,1.4053843934011567,-0.09790213373324297,-0.1664461756216075,2.063338225377154,-0.7842622939081015,-0.3493281113577081,0.08478612682723895,-0.23501011839942096,0.5637010941850982,-1.288967548658644,1.1554242122572953,0.9507440976385911
| 3,376
|
Left ventricular hypertrophy
| 7
| 27
| 2.185403
| 0.028859
|
P12235,O00170,P00403,Q15233,O75880,O75431,Q07021
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
129,187,254,171,112,327,149
|
187,829,327,1862,112,254,547,3302,1481,129,1275,1682,1755,1170,1490,1965,149,2878,171,1363,982,1366,2261,399,1371,1988,2381
|
1.4735171317837568,0.4953400811340294,1.1554242122572953,-0.1664461756216075,1.8366222925568745,1.3145154214917698,0.791441777572769,-1.933174844644704,0.061957638500894446,1.700510440366334,0.17607879404889298,-0.05221706733189361,-0.09790213373324297,0.2445261280106561,0.061957638500894446,-0.21215324764925397,1.609734331636171,-0.8071772923198322,1.5416337356516463,0.13043670441630822,0.38136454893617105,0.13043670441630822,-0.37219848961093516,1.0189877874715023,0.13043670441630822,-0.21215324764925397,-0.4408233191309774
| 3,376
|
Vesicle docking
| 7
| 20
| 2.185315
| 0.028866
|
O60499,O60763,Q12846,Q13190,O43752,Q15833,Q13277
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
12,166,265,150,326,84,475
|
1474,2077,2550,326,12,166,532,2598,3152,2368,1654,265,150,475,84,2483,1771,1249,1226,2687
|
0.061957638500894446,-0.2807305656763728,-0.5552441461593581,1.1554242122572953,3.713524418514359,1.5416337356516463,0.8142050472643398,-0.5781352986923748,-1.2430342742645197,-0.4408233191309774,-0.029377801621022746,1.291793624694478,1.609734331636171,0.8824832327508613,2.063338225377154,-0.5094688519400632,-0.09790213373324297,0.19889667227848584,0.22171244811574498,-0.6239246546713384
| 3,376
|
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
| 6
| 28
| 2.178065
| 0.029401
|
Q9P2W9,Q9H4A6,Q9H9E3,P83436,Q9NZ43,Q8TD16
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
14,312,52,320,290,161
|
1912,2114,2358,2158,2438,2329,1963,1350,2044,751,2478,2369,320,1809,2480,1772,161,1154,1778,451,1418,2680,312,52,290,14,1376,612
|
-0.18929860246142455,-0.30359415686543867,-0.4408233191309774,-0.3264600029423213,-0.48658469438810514,-0.4179460858744323,-0.21215324764925397,0.13043670441630822,-0.2578692219726256,0.5637010941850982,-0.5094688519400632,-0.4408233191309774,1.1781570716463348,-0.12074794835789432,-0.5094688519400632,-0.09790213373324297,1.5870359038920763,0.2673377183743358,-0.09790213373324297,0.9279923914863851,0.10761247991580983,-0.6239246546713384,1.2008880747372999,2.471006836458075,1.2463445321935245,3.5556354942395423,0.13043670441630822,0.7231402673093839
| 3,376
|
Complex i biogenesis
| 10
| 31
| 2.170581
| 0.029963
|
Q16718,P03886,O96000,O75306,Q9Y6M9,Q8N183,O43676,Q9P0J0,O95168,Q7L592
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
233,547,515,197,638,185,21,88,303,424
|
2079,21,998,1998,197,805,303,661,1272,515,547,2693,2325,1925,861,1686,233,1404,424,1773,185,1663,1255,2345,1122,2069,2543,3072,88,2717,638
|
-0.2807305656763728,3.352531486014035,0.35856331139810654,-0.23501011839942096,1.4508080180236562,0.5181290990123865,1.2008880747372999,0.654821087209402,0.17607879404889298,0.8369663760218362,0.791441777572769,-0.6468228743068464,-0.4179460858744323,-0.18929860246142455,0.4725490417782299,-0.05221706733189361,1.382669872986797,0.10761247991580983,0.9734938954710396,-0.09790213373324297,1.496224452836366,-0.029377801621022746,0.19889667227848584,-0.4179460858744323,0.29014722557938266,-0.2578692219726256,-0.5323553332283967,-1.082349393180815,2.063338225377154,-0.6468228743068464,0.7003691781398825
| 3,376
|
Mitochondrial complex i assembly model oxphos system
| 13
| 30
| 2.169018
| 0.030081
|
O95182,Q16718,P03886,O96000,O75306,Q9Y6M9,O43676,O75489,Q8N183,Q9P0J0,Q96CU9,O95168,Q7L592
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
661,233,547,515,197,638,21,805,185,88,759,303,424
|
2079,21,998,197,805,303,661,1272,515,547,2693,2325,1925,861,1686,233,424,185,1663,759,1255,2345,1698,1122,2069,2543,3072,88,2717,638
|
-0.2807305656763728,3.352531486014035,0.35856331139810654,1.4508080180236562,0.5181290990123865,1.2008880747372999,0.654821087209402,0.17607879404889298,0.8369663760218362,0.791441777572769,-0.6468228743068464,-0.4179460858744323,-0.18929860246142455,0.4725490417782299,-0.05221706733189361,1.382669872986797,0.9734938954710396,1.496224452836366,-0.029377801621022746,0.5637010941850982,0.19889667227848584,-0.4179460858744323,-0.05221706733189361,0.29014722557938266,-0.2578692219726256,-0.5323553332283967,-1.082349393180815,2.063338225377154,-0.6468228743068464,0.7003691781398825
| 3,376
|
Focal adhesion sites
| 6
| 31
| 2.165916
| 0.030318
|
O60888,Q969Q5,Q96AC1,P12814,Q13136,P49770
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
3,13,186,248,57,191
|
3,2828,3008,3248,248,777,1757,191,1444,534,57,1656,3321,585,536,1451,268,13,186,2616,1258,2748,2586,2186,1701,1379,683,1828,801,2238,2354
|
5.378564276840684,-0.7613497177385024,-0.9905855228656107,-1.6107991920138482,1.3372353918837696,0.5409161013840437,-0.09790213373324297,1.4735171317837568,0.08478612682723895,0.8142050472643398,2.3804595810299363,-0.029377801621022746,-2.117646103480084,0.7459093931850885,0.8142050472643398,0.08478612682723895,1.291793624694478,3.5556354942395423,1.496224452836366,-0.5781352986923748,0.19889667227848584,-0.6697234659246303,-0.5552441461593581,-0.3264600029423213,-0.05221706733189361,0.13043670441630822,0.654821087209402,-0.12074794835789432,0.5409161013840437,-0.3493281113577081,-0.4179460858744323
| 3,376
|
Functional motor deficit
| 41
| 162
| 2.164576
| 0.03042
|
P07384,P12235,Q9NR77,Q9Y285,P00403,Q9GZY8,Q969Y2,Q07021,P06753,Q15149,O95140,Q8TD16,P20700,Q9H2D1,Q9NWM8,P03886,Q9UNE7,Q8TD30,Q9BQP7,O00170,Q69YN2,P61981,P46020,P10644,Q15833,Q9H0B6,P53701,Q96QK1,O75477,Q96RL7,Q15041,Q9H2C2,P00846,Q8NFF5,O00429,Q9C0D9,Q8NI60,Q06210,O95817,Q9Y2R0,Q969G3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,129,4,136,254,273,399,149,146,536,404,161,155,36,557,547,571,60,590,187,586,333,460,459,84,608,209,87,342,92,477,97,99,506,351,109,111,625,618,116,251
|
187,351,2466,2654,2320,684,1235,3006,828,2431,1196,342,1862,1918,404,2797,618,2798,254,940,99,547,1796,146,1201,128,3268,775,2660,459,3224,129,1275,2086,155,1106,1682,1647,1345,1520,1277,1483,3157,917,1755,2328,918,2294,1075,1442,1315,1170,1963,1171,460,2830,2249,1653,780,2126,3195,624,862,209,1490,1142,946,1965,2519,864,333,1173,691,1840,1207,1145,625,149,732,865,894,1449,1766,1355,2975,1495,2401,2934,1881,477,754,1497,536,2785,2735,84,1884,586,3271,1452,1364,1935,1368,2173,2263,1695,506,111,1662,1663,161,60,2858,905,2268,2742,2534,1938,251,399,1026,2495,87,92,1371,3292,2842,590,990,109,273,1374,608,3372,97,36,1122,1900,1901,4,1468,1062,557,2543,821,1947,1377,2026,767,1855,1302,571,3239,1671,136,116,1788,1554,963,2387,1431,3022
|
1.4735171317837568,1.1099529042532705,-0.5094688519400632,-0.6239246546713384,-0.4179460858744323,0.6320440740122428,0.19889667227848584,-0.9905855228656107,0.4953400811340294,-0.48658469438810514,0.22171244811574498,1.1326894914941044,-0.1664461756216075,-0.18929860246142455,0.9962417903147566,-0.7384395552892268,0.7003691781398825,-0.7384395552892268,1.3145154214917698,0.40416373461270877,1.9500014918186808,0.791441777572769,-0.12074794835789432,1.609734331636171,0.22171244811574498,1.700510440366334,-1.7258692943152663,0.5409161013840437,-0.6239246546713384,0.9052387716538994,-1.4957984470366237,1.700510440366334,0.17607879404889298,-0.2807305656763728,1.5870359038920763,0.29014722557938266,-0.05221706733189361,-0.029377801621022746,0.13043670441630822,0.039127008246021396,0.17607879404889298,0.061957638500894446,-1.2659996034795133,0.4269608745762918,-0.09790213373324297,-0.4179460858744323,0.4269608745762918,-0.3950711452504818,0.31295465596021727,0.08478612682723895,0.15325880693776223,0.2445261280106561,-0.21215324764925397,0.2445261280106561,0.9052387716538994,-0.7613497177385024,-0.37219848961093516,-0.029377801621022746,0.5409161013840437,-0.30359415686543867,-1.3808656899217036,0.7003691781398825,0.4725490417782299,1.4280971068172954,0.061957638500894446,0.2673377183743358,0.40416373461270877,-0.21215324764925397,-0.5323553332283967,0.4725490417782299,1.1554242122572953,0.2445261280106561,0.6320440740122428,-0.14359595996140015,0.22171244811574498,0.2673377183743358,0.7003691781398825,1.609734331636171,0.5864840833173061,0.4725490417782299,0.4497559749392965,0.08478612682723895,-0.09790213373324297,0.13043670441630822,-0.9217889204720701,0.061957638500894446,-0.4637028527189056,-0.8759369071217561,-0.1664461756216075,0.8824832327508613,0.5637010941850982,0.061957638500894446,0.8142050472643398,-0.7155317980973355,-0.6697234659246303,2.063338225377154,-0.1664461756216075,0.7459093931850885,-1.7258692943152663,0.08478612682723895,0.13043670441630822,-0.18929860246142455,0.13043670441630822,-0.3264600029423213,-0.37219848961093516,-0.05221706733189361,0.8597257693570096,1.859301555293337,-0.029377801621022746,-0.029377801621022746,1.5870359038920763,2.3804595810299363,-0.7842622939081015,0.4497559749392965,-0.37219848961093516,-0.6697234659246303,-0.5323553332283967,-0.18929860246142455,1.3372353918837696,1.0189877874715023,0.35856331139810654,-0.5094688519400632,2.063338225377154,2.040674250545313,0.13043670441630822,-1.8410101788328443,-0.7613497177385024,0.7459093931850885,0.38136454893617105,1.881979102274105,1.291793624694478,0.13043670441630822,0.7231402673093839,-5.244320590828346,2.0180085939614734,2.742495377855693,0.29014722557938266,-0.1664461756216075,-0.1664461756216075,5.109040668422138,0.08478612682723895,0.33576001581343007,0.791441777572769,-0.5323553332283967,0.5181290990123865,-0.18929860246142455,0.13043670441630822,-0.23501011839942096,0.5637010941850982,-0.14359595996140015,0.17607879404889298,0.7686765614043631,-1.5417905109978778,-0.029377801621022746,1.6778190444254801,1.8366222925568745,-0.09790213373324297,0.039127008246021396,0.40416373461270877,-0.4408233191309774,0.10761247991580983,-0.9905855228656107
| 3,376
|
Myometrial relaxation and contraction pathways
| 7
| 21
| 2.163369
| 0.030513
|
P27348,P63104,P63218,Q04917,P61981,P31946,P62258
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
156,419,201,169,333,147,90
|
664,459,858,1168,1645,886,1313,2752,156,147,333,90,419,201,1394,169,1574,1971,2907,2943,1828
|
0.654821087209402,0.9052387716538994,0.4725490417782299,0.2445261280106561,-0.029377801621022746,0.4497559749392965,0.15325880693776223,-0.6926264377581445,1.5870359038920763,1.609734331636171,1.1554242122572953,2.040674250545313,0.9734938954710396,1.4508080180236562,0.10761247991580983,1.5416337356516463,0.016294229330441935,-0.21215324764925397,-0.830094721554977,-0.8759369071217561,-0.12074794835789432
| 3,376
|
Regulation of sodium ion transport
| 9
| 17
| 2.162235
| 0.0306
|
O43865,P46934,Q04917,P46939,Q9UHD1,O43707,Q8N668,O14745,P50570
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
577,11,169,646,767,529,538,614,780
|
614,529,577,807,1199,1920,2802,2557,11,646,780,2295,169,1245,538,1665,767
|
0.7003691781398825,0.8142050472643398,0.7459093931850885,0.5181290990123865,0.22171244811574498,-0.18929860246142455,-0.7384395552892268,-0.5552441461593581,3.8037153417241023,0.6775961200071496,0.5409161013840437,-0.3950711452504818,1.5416337356516463,0.19889667227848584,0.8142050472643398,-0.029377801621022746,0.5637010941850982
| 3,376
|
Atp biosynthetic process
| 9
| 22
| 2.159839
| 0.030785
|
P00846,P00403,O75964,O75947,P25705,P48047,Q9UJZ1,P24539,P06576
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,254,8,394,644,461,611,344,122
|
1861,394,8,254,99,2198,122,2967,2471,344,644,1278,975,1315,461,946,1926,667,2174,2714,2424,611
|
-0.1664461756216075,1.0189877874715023,4.186777541252852,1.3145154214917698,1.9500014918186808,-0.3493281113577081,1.7458879968087067,-0.9217889204720701,-0.5094688519400632,1.1326894914941044,0.6775961200071496,0.17607879404889298,0.38136454893617105,0.15325880693776223,0.9052387716538994,0.40416373461270877,-0.18929860246142455,0.654821087209402,-0.3264600029423213,-0.6468228743068464,-0.4637028527189056,0.7231402673093839
| 3,376
|
Response to heat
| 13
| 39
| 2.158768
| 0.030868
|
O60884,P07900,P09601,Q14232,O95391,O15514,P49841,Q9UNE7,O95817,P12270,Q9H078,P49770,P62258
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
724,663,70,649,489,17,364,571,618,247,566,191,90
|
17,1309,724,828,1196,2359,489,618,2554,663,1073,70,1562,247,1645,886,1603,2088,1684,1443,191,364,1877,946,90,1450,649,3183,1538,2577,1328,2105,1160,566,2747,1736,767,2924,571
|
3.465381598964781,0.15325880693776223,0.5864840833173061,0.4953400811340294,0.22171244811574498,-0.4408233191309774,0.8597257693570096,0.7003691781398825,-0.5552441461593581,0.654821087209402,0.31295465596021727,2.2445899756334495,0.016294229330441935,1.3372353918837696,-0.029377801621022746,0.4497559749392965,-0.00654070501984235,-0.2807305656763728,-0.05221706733189361,0.08478612682723895,1.4735171317837568,1.0872144454036603,-0.1664461756216075,0.40416373461270877,2.040674250545313,0.08478612682723895,0.6775961200071496,-1.334911326938496,0.039127008246021396,-0.5552441461593581,0.15325880693776223,-0.2807305656763728,0.2673377183743358,0.7686765614043631,-0.6697234659246303,-0.07505850905423944,0.5637010941850982,-0.8530145902549154,0.7686765614043631
| 3,376
|
Negative regulation of protein containing complex assembly
| 17
| 38
| 2.158177
| 0.030914
|
O00571,Q13813,P16949,P50542,Q12792,P35612,P47755,Q9NUQ9,P52907,Q8IXJ6,P09429,P49841,Q96QK1,P45880,Q9NYL9,P35241,Q01082
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
485,221,34,65,220,712,167,702,113,697,776,364,87,56,544,250,533
|
485,1099,1310,1796,3080,776,34,250,2040,712,3219,56,167,1318,364,65,113,893,2757,533,1012,220,2566,221,813,952,1247,697,87,1986,1629,2958,3229,702,544,2823,1126,1740
|
0.8597257693570096,0.29014722557938266,0.15325880693776223,-0.12074794835789432,-1.105296684161769,0.5409161013840437,2.765109185211371,1.3372353918837696,-0.2578692219726256,0.6092650746483713,-1.4728064994682601,2.3804595810299363,1.5416337356516463,0.15325880693776223,1.0872144454036603,2.2672389993833404,1.8366222925568745,0.4497559749392965,-0.6926264377581445,0.8142050472643398,0.35856331139810654,1.4053843934011567,-0.5552441461593581,1.4053843934011567,0.5181290990123865,0.40416373461270877,0.19889667227848584,0.6320440740122428,2.063338225377154,-0.21215324764925397,-0.00654070501984235,-0.8988616809189766,-1.4957984470366237,0.6320440740122428,0.8142050472643398,-0.7384395552892268,0.29014722557938266,-0.07505850905423944
| 3,376
|
Sensory perception
| 7
| 27
| 2.156143
| 0.031072
|
Q13813,Q12792,P47755,P52907,P09455,P35241,P26038
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
221,220,167,113,179,250,283
|
2548,1193,179,292,1645,2037,283,2870,250,1074,167,1318,892,1760,1876,113,3152,1395,533,220,2637,221,1051,1247,694,926,2315
|
-0.5552441461593581,0.22171244811574498,1.496224452836366,1.2236172265790646,-0.029377801621022746,-0.2578692219726256,1.2463445321935245,-0.8071772923198322,1.3372353918837696,0.31295465596021727,1.5416337356516463,0.15325880693776223,0.4497559749392965,-0.09790213373324297,-0.1664461756216075,1.8366222925568745,-1.2430342742645197,0.10761247991580983,0.8142050472643398,1.4053843934011567,-0.6010287988405737,1.4053843934011567,0.33576001581343007,0.19889667227848584,0.6320440740122428,0.4269608745762918,-0.3950711452504818
| 3,376
|
Sensory processing of sound
| 6
| 19
| 2.146489
| 0.031834
|
Q13813,Q12792,P47755,P52907,P35241,P26038
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
221,220,167,113,250,283
|
2548,1193,292,2037,283,250,1074,167,1318,113,3152,1395,533,220,2637,221,1051,1247,2315
|
-0.5552441461593581,0.22171244811574498,1.2236172265790646,-0.2578692219726256,1.2463445321935245,1.3372353918837696,0.31295465596021727,1.5416337356516463,0.15325880693776223,1.8366222925568745,-1.2430342742645197,0.10761247991580983,0.8142050472643398,1.4053843934011567,-0.6010287988405737,1.4053843934011567,0.33576001581343007,0.19889667227848584,-0.3950711452504818
| 3,376
|
Positive regulation of catabolic process
| 48
| 155
| 2.145878
| 0.031883
|
P12235,Q9BXS4,P46934,P50416,P31751,O15269,O15514,P17980,Q13190,P21796,P14735,Q05397,Q969T7,P26038,Q5PRF9,P07900,P15311,Q7Z739,Q96HY6,Q8IXJ6,Q9UNE7,Q96EP0,O95816,P43686,Q13464,P46459,Q9UNN5,Q14671,P08754,P09601,O94874,Q96B26,Q13596,O75150,Q4ZIN3,Q6UWE0,Q96QK1,Q9P0J0,P62191,Q14103,Q86UE4,P62195,P49841,O95817,P35241,Q96JB5,O75175,O60506
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,391,11,517,516,514,17,642,150,20,641,534,673,283,422,663,292,435,311,697,571,310,178,304,61,583,591,714,445,70,443,204,713,709,464,603,87,88,474,476,626,365,364,618,250,124,488,487
|
2283,2719,2509,2850,2591,514,1232,17,3283,1100,1830,487,804,936,709,488,2358,1831,2155,443,2392,1273,178,618,1796,1274,2323,663,445,776,70,1562,2290,129,641,292,642,1134,20,283,974,516,250,1719,1963,304,1924,1806,583,11,1443,2631,1281,364,517,2981,781,782,2477,946,474,365,1391,1878,2635,1839,3215,534,2832,3124,1969,2207,1048,2129,3359,1398,150,61,713,2252,1177,476,2165,2402,714,1767,2019,2606,1882,464,422,1359,2138,1659,603,1364,1408,2810,2708,435,2811,1248,626,2307,2405,697,1367,1411,1847,2174,2533,2494,1816,1696,673,204,848,2577,310,311,1984,124,87,1986,391,1897,3354,1057,2747,2147,1735,2228,2185,1125,3300,2503,2823,88,1855,1667,1591,2382,1509,3168,2426,2236,571,591,1636,2890,3091,745,2317,912,2239
|
-0.3950711452504818,-0.6697234659246303,-0.5323553332283967,-0.7842622939081015,-0.5781352986923748,0.8369663760218362,0.19889667227848584,3.465381598964781,-1.8179762690089385,0.29014722557938266,-0.14359595996140015,0.8597257693570096,0.5181290990123865,0.40416373461270877,0.6092650746483713,0.8597257693570096,-0.4408233191309774,-0.14359595996140015,-0.3264600029423213,0.9279923914863851,-0.4637028527189056,0.17607879404889298,1.496224452836366,0.7003691781398825,-0.12074794835789432,0.17607879404889298,-0.4179460858744323,0.654821087209402,0.9279923914863851,0.5409161013840437,2.2445899756334495,0.016294229330441935,-0.3950711452504818,1.700510440366334,0.6775961200071496,1.2236172265790646,0.6775961200071496,0.2673377183743358,3.3751044359501514,1.2463445321935245,0.38136454893617105,0.8369663760218362,1.3372353918837696,-0.07505850905423944,-0.21215324764925397,1.2008880747372999,-0.18929860246142455,-0.12074794835789432,0.7459093931850885,3.8037153417241023,0.08478612682723895,-0.6010287988405737,0.17607879404889298,1.0872144454036603,0.8369663760218362,-0.9447186346692006,0.5409161013840437,0.5409161013840437,-0.5094688519400632,0.40416373461270877,0.8824832327508613,1.0872144454036603,0.10761247991580983,-0.1664461756216075,-0.6010287988405737,-0.14359595996140015,-1.4498172605482251,0.8142050472643398,-0.7613497177385024,-1.1741538836336023,-0.21215324764925397,-0.3493281113577081,0.33576001581343007,-0.30359415686543867,-3.135924328813233,0.10761247991580983,1.609734331636171,2.357818723202082,0.6092650746483713,-0.37219848961093516,0.2445261280106561,0.8824832327508613,-0.3264600029423213,-0.4637028527189056,0.6092650746483713,-0.09790213373324297,-0.23501011839942096,-0.5781352986923748,-0.1664461756216075,0.9052387716538994,0.9734938954710396,0.13043670441630822,-0.30359415686543867,-0.029377801621022746,0.7231402673093839,0.13043670441630822,0.10761247991580983,-0.7384395552892268,-0.6468228743068464,0.9507440976385911,-0.7384395552892268,0.19889667227848584,0.7003691781398825,-0.3950711452504818,-0.4637028527189056,0.6320440740122428,0.13043670441630822,0.10761247991580983,-0.14359595996140015,-0.3264600029423213,-0.5323553332283967,-0.5094688519400632,-0.12074794835789432,-0.05221706733189361,0.654821087209402,1.4508080180236562,0.4953400811340294,-0.5552441461593581,1.2008880747372999,1.2008880747372999,-0.21215324764925397,1.7458879968087067,2.063338225377154,-0.21215324764925397,1.0417318922140226,-0.1664461756216075,-2.8807308300643446,0.33576001581343007,-0.6697234659246303,-0.30359415686543867,-0.07505850905423944,-0.3493281113577081,-0.3264600029423213,0.29014722557938266,-1.8870866819578753,-0.5094688519400632,-0.7384395552892268,2.063338225377154,-0.14359595996140015,-0.029377801621022746,0.016294229330441935,-0.4408233191309774,0.061957638500894446,-1.288967548658644,-0.4637028527189056,-0.3493281113577081,0.7686765614043631,0.7459093931850885,-0.00654070501984235,-0.8071772923198322,-1.105296684161769,0.5864840833173061,-0.3950711452504818,0.4497559749392965,-0.3493281113577081
| 3,376
|
Proteasome regulatory particle
| 6
| 19
| 2.145088
| 0.031946
|
P62191,P48556,Q9UNM6,P62195,P43686,O00231
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
474,157,276,365,304,340
|
340,1433,1337,1515,1307,642,1719,304,157,1762,2561,474,365,1391,1082,895,980,1544,276
|
1.1326894914941044,0.08478612682723895,0.13043670441630822,0.039127008246021396,0.15325880693776223,0.6775961200071496,-0.07505850905423944,1.2008880747372999,1.5870359038920763,-0.09790213373324297,-0.5552441461593581,0.8824832327508613,1.0872144454036603,0.10761247991580983,0.31295465596021727,0.4497559749392965,0.38136454893617105,0.039127008246021396,1.291793624694478
| 3,376
|
Oxidoreductase activity acting on nad p h
| 10
| 32
| 2.144415
| 0.032
|
Q13423,O95831,Q16718,P03886,O96000,O75306,Q9Y6M9,O43676,Q9P0J0,O95168
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
354,7,233,547,515,197,638,21,88,303
|
2355,2079,21,998,1998,197,805,303,661,1272,7,515,2690,547,3198,1105,2693,2325,1925,861,1686,979,354,233,1404,1813,1976,2539,88,2772,2717,638
|
-0.4408233191309774,-0.2807305656763728,3.352531486014035,0.35856331139810654,-0.23501011839942096,1.4508080180236562,0.5181290990123865,1.2008880747372999,0.654821087209402,0.17607879404889298,4.321881386246311,0.8369663760218362,-0.6468228743068464,0.791441777572769,-1.403846866269295,0.29014722557938266,-0.6468228743068464,-0.4179460858744323,-0.18929860246142455,0.4725490417782299,-0.05221706733189361,0.38136454893617105,1.1099529042532705,1.382669872986797,0.10761247991580983,-0.12074794835789432,-0.21215324764925397,-0.5323553332283967,2.063338225377154,-0.6926264377581445,-0.6468228743068464,0.7003691781398825
| 3,376
|
Switching of origins to a post replicative state
| 10
| 60
| 2.140056
| 0.03235
|
Q14566,P48556,P61289,Q9UNM6,P28066,Q92530,P62195,P43686,O00231,O43913
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
2,157,219,276,330,114,365,304,340,470
|
340,1433,1337,1515,1305,1307,470,2155,642,2324,808,1386,1870,1387,1482,1871,330,2629,1648,2203,2039,1564,1485,2010,1719,304,157,2951,2667,1204,1762,2561,2296,219,474,365,1391,1111,1208,1082,2932,2569,2096,2,2605,895,602,114,1540,2840,1544,2844,1263,961,2027,2425,1509,1063,276,2318
|
1.1326894914941044,0.08478612682723895,0.13043670441630822,0.039127008246021396,0.15325880693776223,0.15325880693776223,0.8824832327508613,-0.3264600029423213,0.6775961200071496,-0.4179460858744323,0.5181290990123865,0.10761247991580983,-0.1664461756216075,0.10761247991580983,0.061957638500894446,-0.1664461756216075,1.1554242122572953,-0.6010287988405737,-0.029377801621022746,-0.3493281113577081,-0.2578692219726256,0.016294229330441935,0.061957638500894446,-0.23501011839942096,-0.07505850905423944,1.2008880747372999,1.5870359038920763,-0.8988616809189766,-0.6239246546713384,0.22171244811574498,-0.09790213373324297,-0.5552441461593581,-0.3950711452504818,1.4053843934011567,0.8824832327508613,1.0872144454036603,0.10761247991580983,0.29014722557938266,0.22171244811574498,0.31295465596021727,-0.8759369071217561,-0.5552441461593581,-0.2807305656763728,5.625472030171659,-0.5781352986923748,0.4497559749392965,0.7231402673093839,1.8366222925568745,0.039127008246021396,-0.7613497177385024,0.039127008246021396,-0.7613497177385024,0.19889667227848584,0.40416373461270877,-0.23501011839942096,-0.4637028527189056,0.061957638500894446,0.33576001581343007,1.291793624694478,-0.3950711452504818
| 3,376
|
Late endosomal microautophagy
| 6
| 11
| 2.139078
| 0.032429
|
O60664,O43633,A5D8V6,Q9UQN3,Q9H9H4,P08670
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
723,594,513,704,409,63
|
513,594,723,63,1797,1986,2106,409,821,704,1746
|
0.8369663760218362,0.7231402673093839,0.5864840833173061,2.312532127633527,-0.12074794835789432,-0.21215324764925397,-0.2807305656763728,0.9962417903147566,0.5181290990123865,0.6320440740122428,-0.07505850905423944
| 3,376
|
Cellular response to heat
| 13
| 28
| 2.138909
| 0.032443
|
P07900,P09601,P17612,O75190,Q9UHD1,O95391,O15514,P49841,Q9UNE7,O95817,P12270,Q9H078,P62258
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
663,70,886,828,767,489,17,364,571,618,247,566,90
|
17,1309,828,1196,489,618,2554,663,1073,70,1562,247,1645,886,1603,1684,364,946,90,3183,1538,2577,2105,1160,566,2747,767,571
|
3.465381598964781,0.15325880693776223,0.4953400811340294,0.22171244811574498,0.8597257693570096,0.7003691781398825,-0.5552441461593581,0.654821087209402,0.31295465596021727,2.2445899756334495,0.016294229330441935,1.3372353918837696,-0.029377801621022746,0.4497559749392965,-0.00654070501984235,-0.05221706733189361,1.0872144454036603,0.40416373461270877,2.040674250545313,-1.334911326938496,0.039127008246021396,-0.5552441461593581,-0.2807305656763728,0.2673377183743358,0.7686765614043631,-0.6697234659246303,0.5637010941850982,0.7686765614043631
| 3,376
|
Protein insertion into membrane
| 11
| 30
| 2.131851
| 0.033019
|
P49069,Q15629,P07900,O14737,Q96A33,Q9NS69,Q8N4V1,Q9P0J0,O43681,Q9P0I2,Q8WWC4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
689,35,663,576,698,22,86,88,684,229,356
|
576,965,684,1100,806,663,2870,1717,1806,689,3028,1150,1084,35,1884,2573,1622,86,2057,356,698,2278,22,229,88,1671,1472,3272,746,1856
|
0.7459093931850885,0.38136454893617105,0.6320440740122428,0.29014722557938266,0.5181290990123865,0.654821087209402,-0.8071772923198322,-0.07505850905423944,-0.12074794835789432,0.6320440740122428,-1.0135227149606314,0.2673377183743358,0.31295465596021727,2.765109185211371,-0.1664461756216075,-0.5552441461593581,-0.00654070501984235,2.063338225377154,-0.2578692219726256,1.1099529042532705,0.6320440740122428,-0.37219848961093516,3.352531486014035,1.4053843934011567,2.063338225377154,-0.029377801621022746,0.08478612682723895,-1.7258692943152663,0.5864840833173061,-0.14359595996140015
| 3,376
|
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand
| 12
| 31
| 2.126287
| 0.033479
|
O60884,P07900,O75935,O43237,Q14203,P47755,Q13561,Q13451,Q9Y6G9,P52907,P68371,P31948
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
724,663,413,639,334,167,242,787,574,113,784,405
|
639,724,413,663,1073,1562,1797,1603,2088,405,167,1318,113,1877,1320,1722,784,1012,2130,787,242,1356,334,2401,843,2496,1546,991,2586,2652,574
|
0.6775961200071496,0.5864840833173061,0.9734938954710396,0.654821087209402,0.31295465596021727,0.016294229330441935,-0.12074794835789432,-0.00654070501984235,-0.2807305656763728,0.9962417903147566,1.5416337356516463,0.15325880693776223,1.8366222925568745,-0.1664461756216075,0.15325880693776223,-0.07505850905423944,0.5409161013840437,0.35856331139810654,-0.30359415686543867,0.5409161013840437,1.359953540760634,0.13043670441630822,1.1554242122572953,-0.4637028527189056,0.4953400811340294,-0.5094688519400632,0.039127008246021396,0.38136454893617105,-0.5552441461593581,-0.6010287988405737,0.7686765614043631
| 3,376
|
Subsets and Splits
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