term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platyspondyly
| 9
| 36
| 2.098752
| 0.035839
|
Q7RTS9,Q96L58,P08236,Q32P28,P48735,O95831,Q5JRA6,P04066,P16278
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,166,247,74,306,86,384,282,283
|
2204,627,2014,1202,2806,86,1070,282,247,283,2573,1638,2433,2434,306,1120,1444,1786,1548,1219,746,1738,74,384,1308,663,32,2524,436,528,166,793,2241,2595,1421,2374
|
-0.4382834749199662,0.5685132566383815,-0.3217563066408477,0.14413493056950505,-1.000530653277979,2.119398055387944,0.22183326505174678,1.0880085580638097,1.172767077784285,1.0880085580638097,-0.7112482098625537,-0.09685523182921355,-0.5880217491572218,-0.5880217491572218,1.023417311456126,0.19607443889255075,0.011755338385683791,-0.17996198897025922,-0.042241579625993585,0.14413493056950505,0.47202132781882844,-0.15209923198018688,2.3039419144770994,0.8915034664671595,0.0916230653837448,0.5445741216866079,3.210375491197299,-0.6492423972397605,0.8241310428665671,0.709655477037906,1.516747891198495,0.4475879086837396,-0.4382834749199662,-0.7112482098625537,0.038526658332115674,-0.5275674680675104
| 3,120
|
Muscle spasm
| 14
| 62
| 2.092285
| 0.036413
|
P04792,P35637,Q9UQN3,P07196,Q9H6K4,P06280,O75298,Q15165,P00846,O95140,Q92804,Q13501,Q9NR77,Q92734
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,248,132,103,174,232,110,112,52,332,153,382,126,386
|
1624,1379,2504,110,856,332,1295,2879,2381,52,1773,128,1249,232,2019,103,3002,1911,1387,1339,1437,2808,1484,379,1392,248,2338,1487,861,1344,1442,608,2397,1215,2030,2398,2438,1261,2610,1221,382,714,112,2227,1455,782,587,1838,386,153,2126,1606,3051,900,2820,174,671,126,1327,132,2934,533
|
-0.09685523182921355,0.038526658332115674,-0.6492423972397605,1.8551713497297029,0.37352278495630703,0.9579237536502591,0.0916230653837448,-1.1348420125464262,-0.5576999615504026,2.7276227820437797,-0.17996198897025922,1.7264856813353782,0.11795129526109982,1.2353427068536198,-0.3217563066408477,1.9271271193823978,-1.4877287999834443,-0.2645349940023304,0.038526658332115674,0.06514870608694326,0.011755338385683791,-1.000530653277979,-0.015166862701093613,0.8915034664671595,0.038526658332115674,1.172767077784285,-0.5275674680675104,-0.015166862701093613,0.37352278495630703,0.06514870608694326,0.011755338385683791,0.5923317961811347,-0.5576999615504026,0.14413493056950505,-0.3217563066408477,-0.5576999615504026,-0.5880217491572218,0.11795129526109982,-0.7425516146318213,0.14413493056950505,0.8915034664671595,0.4963293559988893,1.8370056925799199,-0.4382834749199662,0.011755338385683791,0.4475879086837396,0.616030896851247,-0.20798764245173287,0.8915034664671595,1.555594300107399,-0.37966711166030426,-0.0694704733838678,-1.7895331421785752,0.3485751885508132,-1.000530653277979,1.4775738794299105,0.5445741216866079,1.763620063558507,0.0916230653837448,1.7078061122023387,-1.238060398252917,0.709655477037906
| 3,120
|
golgi
| 10
| 66
| 2.089571
| 0.036656
|
Q8NBN3,Q9UI14,O15127,Q5VW38,Q15907,Q9Y487,Q8IZA0,Q8IXU6,P36543,Q15904
|
Localization
|
OpenCell Localization
|
opencell_localization
|
35,237,107,47,49,150,279,22,213,186
|
1621,2564,2924,1149,1964,2862,107,2378,2056,768,2568,1295,655,1714,1677,1032,2574,1874,213,2514,994,284,2866,2470,1877,2882,1729,1823,1167,2165,1933,1786,863,1941,745,1554,778,186,49,47,2732,22,279,1314,35,1180,1888,2076,666,544,387,790,970,2049,1574,2132,2197,649,1961,237,1194,1027,1707,1618,150,1520
|
-0.09685523182921355,-0.7112482098625537,-1.238060398252917,0.17017548246536693,-0.29306044672954845,-1.1009154766800557,1.873265791868123,-0.5576999615504026,-0.35062453129738713,0.4475879086837396,-0.7112482098625537,0.0916230653837448,0.5445741216866079,-0.15209923198018688,-0.12439757025387724,0.24745340385816628,-0.7112482098625537,-0.23617802356071166,1.297090899466863,-0.6492423972397605,0.2729362763877655,1.0880085580638097,-1.1009154766800557,-0.6185351182463072,-0.23617802356071166,-1.1348420125464262,-0.15209923198018688,-0.20798764245173287,0.17017548246536693,-0.4088860728488319,-0.2645349940023304,-0.17996198897025922,0.37352278495630703,-0.2645349940023304,0.47202132781882844,-0.042241579625993585,0.4475879086837396,1.4380669400587471,2.801929332566857,2.816645631587557,-0.902175152364751,3.74297377627154,1.1093425443192109,0.0916230653837448,3.156189494592303,0.17017548246536693,-0.23617802356071166,-0.35062453129738713,0.5445741216866079,0.6864228881683501,0.8915034664671595,0.4475879086837396,0.298283282312465,-0.3217563066408477,-0.042241579625993585,-0.37966711166030426,-0.4088860728488319,0.5685132566383815,-0.2645349940023304,1.2353427068536198,0.17017548246536693,0.2729362763877655,-0.12439757025387724,-0.0694704733838678,1.5748962832288216,-0.015166862701093613
| 3,120
|
Mitochondrial atp synthesis coupled proton transport
| 6
| 11
| 2.086175
| 0.036963
|
O75947,O75964,P00846,P06576,P36542,P24539
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
252,114,52,422,305,94
|
252,114,52,422,94,919,305,955,2849,883,512
|
1.1517209730784248,1.818768282448762,2.7276227820437797,0.8241310428665671,2.050407604865225,0.32349580032456454,1.023417311456126,0.298283282312465,-1.0672234487170145,0.3485751885508132,0.7327741710393836
| 3,120
|
Prominent nasal bridge
| 11
| 45
| 2.081476
| 0.03739
|
P21964,O95721,Q69YQ0,Q10471,P20700,Q10713,P13073,P42892,Q8WVM7,Q96EK5,Q5JRA6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
466,69,136,351,288,105,42,43,209,479,384
|
2531,1289,2749,1151,1712,69,42,288,466,2155,1921,1644,1213,43,2753,1121,958,2470,1546,2757,1549,351,105,1450,747,490,1554,1687,384,136,209,751,479,1187,1569,1463,2888,2236,2668,1512,970,2193,762,763,2961
|
-0.6801459566044995,0.0916230653837448,-0.9347396848564197,0.17017548246536693,-0.15209923198018688,2.3692468623114746,2.875037373385399,1.0665769311873845,0.7786741122076469,-0.4088860728488319,-0.2645349940023304,-0.09685523182921355,0.14413493056950505,2.875037373385399,-0.9347396848564197,0.19607443889255075,0.298283282312465,-0.6185351182463072,-0.042241579625993585,-0.9347396848564197,-0.042241579625993585,0.9358878616746352,1.9092431533941194,0.011755338385683791,0.47202132781882844,0.75578003326324,-0.042241579625993585,-0.12439757025387724,0.8915034664671595,1.6702193073777245,1.3174933512024687,0.47202132781882844,0.7786741122076469,0.17017548246536693,-0.042241579625993585,0.011755338385683791,-1.1348420125464262,-0.4382834749199662,-0.8057719361207141,-0.015166862701093613,0.298283282312465,-0.4088860728488319,0.47202132781882844,0.47202132781882844,-1.3081044921965708
| 3,120
|
Phospholipid metabolic process
| 8
| 74
| 2.077914
| 0.037717
|
P35790,Q8NHP8,Q9NPH0,Q9NX62,Q10713,Q8NCC3,Q9BVG9,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,37,5,137,105,21,85,28
|
2671,2501,156,2924,1377,979,2804,1769,1202,1481,2297,375,2623,2018,829,953,2302,605,2574,2256,0,709,2338,2847,3004,3059,1121,1980,1648,1786,2223,105,2944,1880,1455,1688,2178,1883,1796,1405,1050,2358,1837,21,868,37,894,28,1838,1183,1235,506,668,669,341,259,558,2819,2188,85,1804,2047,5,1370,2132,3000,137,2957,1242,2197,2199,2562,512,2618
|
-0.8376939983695894,-0.6492423972397605,1.5362117181364128,-1.238060398252917,0.038526658332115674,0.2729362763877655,-1.000530653277979,-0.17996198897025922,0.14413493056950505,-0.015166862701093613,-0.4976220214613302,0.8915034664671595,-0.7740586736982547,-0.3217563066408477,0.39833990773856,0.298283282312465,-0.4976220214613302,0.5923317961811347,-0.7112482098625537,-0.46786141367036915,5.899253810656477,0.4963293559988893,-0.5275674680675104,-1.0672234487170145,-1.4877287999834443,-1.9076504275094626,0.19607443889255075,-0.29306044672954845,-0.09685523182921355,-0.17996198897025922,-0.4382834749199662,1.9092431533941194,-1.2729570159514279,-0.23617802356071166,0.011755338385683791,-0.12439757025387724,-0.4088860728488319,-0.23617802356071166,-0.17996198897025922,0.038526658332115674,0.24745340385816628,-0.5275674680675104,-0.20798764245173287,3.7786917531689994,0.37352278495630703,3.1288498896389405,0.3485751885508132,3.369120265484028,-0.20798764245173287,0.17017548246536693,0.14413493056950505,0.7327741710393836,0.5445741216866079,0.5445741216866079,0.9579237536502591,1.1517209730784248,0.6630753264781283,-1.000530653277979,-0.4088860728488319,2.153508561251972,-0.17996198897025922,-0.3217563066408477,4.657618122456405,0.06514870608694326,-0.37966711166030426,-1.451273498282404,1.651310887354022,-1.3081044921965708,0.14413493056950505,-0.4088860728488319,-0.4088860728488319,-0.6801459566044995,0.7327741710393836,-0.7425516146318213
| 3,120
|
Hydrolase activity acting on glycosyl bonds
| 9
| 27
| 2.074414
| 0.038041
|
Q9NUJ1,O75503,P54802,P06280,P08236,P04066,P16278,P17900,O60476
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
167,27,264,232,247,282,283,190,158
|
1029,158,563,27,1773,282,232,400,829,247,2429,2535,1438,283,190,860,3041,1717,3010,2629,264,2349,2115,1740,309,167,2081
|
0.24745340385816628,1.5362117181364128,0.6396116988763457,3.44643436310832,-0.17996198897025922,1.0880085580638097,1.2353427068536198,0.8466959209611702,0.39833990773856,1.172767077784285,-0.5880217491572218,-0.6801459566044995,0.011755338385683791,1.0880085580638097,1.4181869234230973,0.37352278495630703,-1.712329994309814,-0.15209923198018688,-1.5244569016571512,-0.7740586736982547,1.1305797371850148,-0.5275674680675104,-0.37966711166030426,-0.15209923198018688,1.023417311456126,1.516747891198495,-0.35062453129738713
| 3,120
|
Abnormal metacarpal morphology
| 7
| 32
| 2.068967
| 0.038549
|
Q7RTS9,Q96L58,Q9NX62,Q32P28,P08236,O75962,P16278
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,166,137,74,247,273,283
|
2331,2749,2503,1431,1905,2014,273,247,807,283,1209,2573,1302,1875,2159,1450,746,1738,747,74,2664,2072,32,166,341,1571,2412,970,793,1848,137,762
|
-0.5275674680675104,-0.9347396848564197,-0.6492423972397605,0.011755338385683791,-0.2645349940023304,-0.3217563066408477,1.1093425443192109,1.172767077784285,0.42302785571210444,1.0880085580638097,0.14413493056950505,-0.7112482098625537,0.0916230653837448,-0.23617802356071166,-0.4088860728488319,0.011755338385683791,0.47202132781882844,-0.15209923198018688,0.47202132781882844,2.3039419144770994,-0.8057719361207141,-0.35062453129738713,3.210375491197299,1.516747891198495,0.9579237536502591,-0.042241579625993585,-0.5576999615504026,0.298283282312465,0.4475879086837396,-0.20798764245173287,1.651310887354022,0.47202132781882844
| 3,120
|
Golgi apparatus
| 38
| 172
| 2.067458
| 0.038691
|
Q9NX62,Q8TEY7,P80303,Q8IZA0,Q8IXU6,Q9HB40,P16278,P53367,Q02818,O60476,Q7RTS9,Q8NCH0,O15260,Q8NBN3,Q5VW38,P50897,O60637,Q8TDW0,Q8TD16,O95456,Q8N4Q0,Q5BJH7,Q96ND0,Q9HD45,Q8NC54,O15212,Q93050,Q10471,O15127,P11717,Q9BSL1,P82094,P24390,Q92896,Q9BXB4,Q96C57,Q96JB2,Q8NEY8
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
137,142,15,279,22,24,283,284,30,158,32,161,157,35,47,51,55,189,188,302,60,318,195,199,71,212,99,351,107,233,235,366,116,118,387,121,122,257
|
1582,1709,2292,1859,374,1621,2564,1964,905,107,212,2378,157,2140,625,3001,2945,704,1290,766,907,158,1904,448,55,767,1151,2056,2014,2057,878,1672,730,302,2018,1071,1633,770,1072,3064,233,283,2880,880,2574,116,708,2752,2255,2895,3010,2388,1874,1159,1255,2514,1303,1927,1304,994,1724,2102,51,2468,2469,284,2396,2866,633,487,15,366,1825,2108,684,30,1219,2223,1126,863,351,1401,1941,2547,961,776,2851,2549,1740,318,616,2761,3047,47,1175,1499,663,1500,2762,1005,929,2072,32,2314,2483,2790,1355,1231,812,22,665,279,2181,60,1314,35,71,161,257,1180,542,188,2736,189,142,936,2076,118,1052,99,666,544,2276,121,122,1319,195,695,723,2235,755,2080,2764,1272,235,848,597,387,790,942,2931,1104,2049,671,3052,1612,24,199,2284,1515,2132,1192,137,649,2199,1282,2968,729,1061,2135,2961,1520
|
-0.0694704733838678,-0.15209923198018688,-0.4976220214613302,-0.23617802356071166,0.8915034664671595,-0.09685523182921355,-0.7112482098625537,-0.29306044672954845,0.32349580032456454,1.873265791868123,1.297090899466863,-0.5576999615504026,1.5362117181364128,-0.4088860728488319,0.5685132566383815,-1.4877287999834443,-1.3081044921965708,0.4963293559988893,0.0916230653837448,0.4475879086837396,0.32349580032456454,1.5362117181364128,-0.2645349940023304,0.8014574420423553,2.575259739826172,0.4475879086837396,0.17017548246536693,-0.35062453129738713,-0.3217563066408477,-0.35062453129738713,0.3485751885508132,-0.12439757025387724,0.47202132781882844,1.023417311456126,-0.3217563066408477,0.22183326505174678,-0.09685523182921355,0.4475879086837396,0.22183326505174678,-1.947658572174278,1.2353427068536198,1.0880085580638097,-1.1348420125464262,0.3485751885508132,-0.7112482098625537,1.8004585753415925,0.4963293559988893,-0.9347396848564197,-0.46786141367036915,-1.169006197935009,-1.5244569016571512,-0.5576999615504026,-0.23617802356071166,0.17017548246536693,0.11795129526109982,-0.6492423972397605,0.0916230653837448,-0.2645349940023304,0.0916230653837448,0.2729362763877655,-0.15209923198018688,-0.37966711166030426,2.757491625277111,-0.6185351182463072,-0.6185351182463072,1.0880085580638097,-0.5576999615504026,-1.1009154766800557,0.5685132566383815,0.75578003326324,4.05454044544889,0.9137480795405156,-0.20798764245173287,-0.37966711166030426,0.5205132181705904,3.3299572675677735,0.14413493056950505,-0.4382834749199662,0.19607443889255075,0.37352278495630703,0.9358878616746352,0.038526658332115674,-0.2645349940023304,-0.6801459566044995,0.298283282312465,0.4475879086837396,-1.0672234487170145,-0.6801459566044995,-0.15209923198018688,1.001687568375461,0.5923317961811347,-0.9347396848564197,-1.7507804815018162,2.816645631587557,0.17017548246536693,-0.015166862701093613,0.5445741216866079,-0.015166862701093613,-0.9347396848564197,0.2729362763877655,0.32349580032456454,-0.35062453129738713,3.210375491197299,-0.4976220214613302,-0.6185351182463072,-0.9675239012000673,0.06514870608694326,0.14413493056950505,0.42302785571210444,3.74297377627154,0.5445741216866079,1.1093425443192109,-0.4088860728488319,2.4813316430188412,0.0916230653837448,3.156189494592303,2.3692468623114746,1.5362117181364128,1.1517209730784248,0.17017548246536693,0.6864228881683501,1.4380669400587471,-0.902175152364751,1.4380669400587471,1.6132609997025542,0.32349580032456454,-0.35062453129738713,1.8004585753415925,0.24745340385816628,1.9979768307458792,0.5445741216866079,0.6864228881683501,-0.46786141367036915,1.7820760211495976,1.7820760211495976,0.0916230653837448,1.3781703257871583,0.5205132181705904,0.4963293559988893,-0.4382834749199662,0.47202132781882844,-0.35062453129738713,-0.9347396848564197,0.11795129526109982,1.2353427068536198,0.39833990773856,0.616030896851247,0.8915034664671595,0.4475879086837396,0.32349580032456454,-1.238060398252917,0.22183326505174678,-0.3217563066408477,0.5445741216866079,-1.7895331421785752,-0.0694704733838678,3.706966810655375,1.3580323311839413,-0.46786141367036915,-0.015166862701093613,-0.37966711166030426,0.17017548246536693,1.651310887354022,0.5685132566383815,-0.4088860728488319,0.11795129526109982,-1.3435062986012638,0.4963293559988893,0.24745340385816628,-0.37966711166030426,-1.3081044921965708,-0.015166862701093613
| 3,120
|
Nuclear envelope organization
| 12
| 33
| 2.066026
| 0.038826
|
P02545,Q9UQN3,P50402,P20700,Q9ULX6,Q9Y3E7,Q86XL3,Q9UH99,Q5JTV8,Q9HD42,O75844,Q8NC56
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
376,132,289,288,231,203,434,210,432,260,123,287
|
2454,2702,2970,908,123,1294,376,2304,288,3004,289,1259,1221,714,432,434,1562,460,287,2486,1660,1054,2192,792,260,1413,210,231,1853,624,132,763,203
|
-0.6185351182463072,-0.8698275055005745,-1.379165978216167,0.32349580032456454,1.763620063558507,0.0916230653837448,0.8915034664671595,-0.4976220214613302,1.0665769311873845,-1.4877287999834443,1.0665769311873845,0.11795129526109982,0.14413493056950505,0.4963293559988893,0.8241310428665671,0.8241310428665671,-0.042241579625993585,0.8014574420423553,1.0880085580638097,-0.6185351182463072,-0.09685523182921355,0.24745340385816628,-0.4088860728488319,0.4475879086837396,1.1517209730784248,0.038526658332115674,1.3174933512024687,1.256016338166523,-0.20798764245173287,0.5923317961811347,1.7078061122023387,0.47202132781882844,1.3378069158806978
| 3,120
|
Rhof gtpase cycle
| 6
| 18
| 2.065688
| 0.038858
|
O00459,Q8TAA9,P20700,P42167,Q5JTV8,P80723
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
156,131,288,207,432,184
|
1857,156,1292,1201,733,288,467,207,2726,2064,184,1445,432,131,969,1664,728,1196
|
-0.23617802356071166,1.5362117181364128,0.0916230653837448,0.14413493056950505,0.47202132781882844,1.0665769311873845,0.7786741122076469,1.3174933512024687,-0.902175152364751,-0.35062453129738713,1.4380669400587471,0.011755338385683791,0.8241310428665671,1.7078061122023387,0.298283282312465,-0.09685523182921355,0.4963293559988893,0.17017548246536693
| 3,120
|
Udp glycosyltransferase activity
| 8
| 13
| 2.062226
| 0.039186
|
P06865,O60568,O43505,Q96L58,Q10471,Q9NYU2,P13807,Q10472
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
400,627,34,166,351,796,678,471
|
1150,34,627,400,829,678,2680,351,471,1503,1359,166,796
|
0.17017548246536693,3.1697972893617217,0.5685132566383815,0.8466959209611702,0.39833990773856,0.5205132181705904,-0.8376939983695894,0.9358878616746352,0.7786741122076469,-0.015166862701093613,0.06514870608694326,1.516747891198495,0.4475879086837396
| 3,120
|
Anencephaly
| 6
| 13
| 2.055745
| 0.039807
|
P21964,Q92917,O43505,Q8TAA9,Q15427,O75792
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
466,720,34,131,490,676
|
1289,1624,34,676,1389,466,2470,2162,490,131,751,720,1375
|
0.0916230653837448,-0.09685523182921355,3.1697972893617217,0.5205132181705904,0.038526658332115674,0.7786741122076469,-0.6185351182463072,-0.4088860728488319,0.75578003326324,1.7078061122023387,0.47202132781882844,0.4963293559988893,0.06514870608694326
| 3,120
|
Ceramide metabolic process
| 6
| 17
| 2.054311
| 0.039946
|
P06865,Q13510,P06280,Q8NCC3,Q99805,P17900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
400,44,232,21,154,190
|
802,979,2804,1379,449,1773,232,400,829,190,1640,2223,44,586,21,154,2957
|
0.42302785571210444,0.2729362763877655,-1.000530653277979,0.038526658332115674,0.8014574420423553,-0.17996198897025922,1.2353427068536198,0.8466959209611702,0.39833990773856,1.4181869234230973,-0.09685523182921355,-0.4382834749199662,2.860509873296997,0.616030896851247,3.7786917531689994,1.555594300107399,-1.3081044921965708
| 3,120
|
Synaptic membrane
| 21
| 45
| 2.044781
| 0.040876
|
P20020,Q8IUD2,Q99720,O43815,Q9UQB8,O75787,P09496,P57105,Q96A49,Q8NCG7,Q96EY1,Q96SB3,Q14168,Q15375,Q13492,P52292,P46939,Q92542,Q16643,P09104,Q12959
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
377,783,6,877,13,768,655,405,544,557,438,696,571,686,685,455,584,359,864,858,502
|
1334,2531,877,2909,768,911,858,655,1714,1156,1590,377,1777,1391,1642,2753,584,1724,1876,455,405,1169,2069,502,685,2661,1449,571,2117,686,864,783,2183,557,2641,359,544,1318,438,696,6,2080,2188,1579,13
|
0.06514870608694326,-0.6801459566044995,0.3485751885508132,-1.2034112370325538,0.4475879086837396,0.32349580032456454,0.37352278495630703,0.5445741216866079,-0.15209923198018688,0.17017548246536693,-0.0694704733838678,0.8915034664671595,-0.17996198897025922,0.038526658332115674,-0.09685523182921355,-0.9347396848564197,0.616030896851247,-0.15209923198018688,-0.23617802356071166,0.8014574420423553,0.8466959209611702,0.17017548246536693,-0.35062453129738713,0.7327741710393836,0.5205132181705904,-0.8057719361207141,0.011755338385683791,0.6396116988763457,-0.37966711166030426,0.5205132181705904,0.37352278495630703,0.4475879086837396,-0.4088860728488319,0.6630753264781283,-0.7740586736982547,0.9358878616746352,0.6864228881683501,0.0916230653837448,0.8241310428665671,0.5205132181705904,4.647892361308431,-0.35062453129738713,-0.4088860728488319,-0.042241579625993585,4.164591374905695
| 3,120
|
Skin nodule
| 7
| 21
| 2.042421
| 0.04111
|
Q13510,Q9NSE4,P06280,Q9NZ08,P48735,P35637,P21912
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
44,344,232,145,306,248,378
|
1202,1154,232,1157,452,378,708,1642,248,306,2214,2608,1084,1786,2583,44,778,937,344,145,763
|
0.14413493056950505,0.17017548246536693,1.2353427068536198,0.17017548246536693,0.8014574420423553,0.8915034664671595,0.4963293559988893,-0.09685523182921355,1.172767077784285,1.023417311456126,-0.4382834749199662,-0.7425516146318213,0.22183326505174678,-0.17996198897025922,-0.7112482098625537,2.860509873296997,0.4475879086837396,0.32349580032456454,0.9579237536502591,1.5941183060567525,0.47202132781882844
| 3,120
|
Electron transport chain oxphos system in mitochondria
| 17
| 54
| 2.038633
| 0.041487
|
O75947,P14406,P20674,P13073,O14548,Q9Y6N1,O75964,P00846,Q7KZN9,O96000,P36542,Q9UDW1,P22695,O14949,P14927,P24539,P21912
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
252,72,349,42,388,204,114,52,335,124,305,56,303,26,93,94,378
|
3109,1522,388,26,3070,2602,2909,2294,2505,1152,1908,252,114,654,1711,984,2425,124,604,52,3087,2147,422,913,2383,2808,2536,42,72,93,1388,2152,349,378,303,94,919,1342,2387,2513,305,2575,955,2833,2927,2849,883,716,1002,335,56,1764,764,204
|
-3.4883531035688655,-0.042241579625993585,0.8691530690352253,3.459191262825689,-2.0696602571110043,-0.7425516146318213,-1.2034112370325538,-0.4976220214613302,-0.6492423972397605,0.17017548246536693,-0.2645349940023304,1.1517209730784248,1.818768282448762,0.5445741216866079,-0.15209923198018688,0.2729362763877655,-0.5880217491572218,1.763620063558507,0.5923317961811347,2.7276227820437797,-2.499432291736275,-0.4088860728488319,0.8241310428665671,0.32349580032456454,-0.5576999615504026,-1.000530653277979,-0.6801459566044995,2.875037373385399,2.336710950263473,2.050407604865225,0.038526658332115674,-0.4088860728488319,0.9358878616746352,0.8915034664671595,1.023417311456126,2.050407604865225,0.32349580032456454,0.06514870608694326,-0.5576999615504026,-0.6492423972397605,1.023417311456126,-0.7112482098625537,0.298283282312465,-1.0337628479999912,-1.238060398252917,-1.0672234487170145,0.3485751885508132,0.4963293559988893,0.2729362763877655,0.9579237536502591,2.575259739826172,-0.15209923198018688,0.47202132781882844,1.3378069158806978
| 3,120
|
Hydrolase activity hydrolyzing o glycosyl compounds
| 9
| 20
| 2.029421
| 0.042415
|
Q9NUJ1,P54802,Q9BTY2,P06280,P08236,P04066,P16278,P17900,O60476
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
167,264,309,232,247,282,283,190,158
|
158,563,1773,282,232,400,829,247,2429,283,190,3010,2629,264,2349,2115,1740,309,167,2081
|
1.5362117181364128,0.6396116988763457,-0.17996198897025922,1.0880085580638097,1.2353427068536198,0.8466959209611702,0.39833990773856,1.172767077784285,-0.5880217491572218,1.0880085580638097,1.4181869234230973,-1.5244569016571512,-0.7740586736982547,1.1305797371850148,-0.5275674680675104,-0.37966711166030426,-0.15209923198018688,1.023417311456126,1.516747891198495,-0.35062453129738713
| 3,120
|
Distal muscle weakness
| 16
| 65
| 2.028052
| 0.042555
|
P04792,P02545,Q99720,P07196,P06753,P22626,Q9Y4W6,P41440,Q86U42,P00846,O95831,P35637,Q8TD16,Q13501,Q9NR77,O95140
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,376,6,103,450,321,345,73,337,52,86,248,188,382,126,332
|
579,979,2804,856,677,332,1295,86,52,376,128,450,103,2428,1339,1210,1917,2254,321,1871,2948,248,1118,2338,1487,73,861,2680,1781,1724,2064,2706,1215,2609,2398,2438,2542,2758,1219,2610,1221,382,714,2548,1992,1001,1556,1558,1457,1094,337,1050,2232,188,1800,2794,558,6,480,126,2562,949,345,2969,533
|
0.616030896851247,0.2729362763877655,-1.000530653277979,0.37352278495630703,0.5205132181705904,0.9579237536502591,0.0916230653837448,2.119398055387944,2.7276227820437797,0.8915034664671595,1.7264856813353782,0.8014574420423553,1.9271271193823978,-0.5880217491572218,0.06514870608694326,0.14413493056950505,-0.2645349940023304,-0.46786141367036915,0.979856683830239,-0.23617802356071166,-1.3081044921965708,1.172767077784285,0.19607443889255075,-0.5275674680675104,-0.015166862701093613,2.3039419144770994,0.37352278495630703,-0.8376939983695894,-0.17996198897025922,-0.15209923198018688,-0.35062453129738713,-0.8698275055005745,0.14413493056950505,-0.7425516146318213,-0.5576999615504026,-0.5880217491572218,-0.6801459566044995,-0.9347396848564197,0.14413493056950505,-0.7425516146318213,0.14413493056950505,0.8915034664671595,0.4963293559988893,-0.6801459566044995,-0.29306044672954845,0.2729362763877655,-0.042241579625993585,-0.042241579625993585,0.011755338385683791,0.22183326505174678,0.9579237536502591,0.24745340385816628,-0.4382834749199662,1.4380669400587471,-0.17996198897025922,-0.9675239012000673,0.6630753264781283,4.647892361308431,0.7786741122076469,1.763620063558507,-0.6801459566044995,0.32349580032456454,0.9579237536502591,-1.3435062986012638,0.709655477037906
| 3,120
|
Mitochondrial protein import
| 11
| 34
| 2.024061
| 0.042964
|
Q15388,Q8N4H5,Q10713,Q13505,O14925,O60830,Q9NX63,P06576,Q9NS69,Q5JRX3,P21796
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
294,70,105,76,171,176,312,422,261,307,160
|
171,1030,176,2506,464,1814,1587,1629,1711,1631,422,1774,1715,2808,2536,160,919,1542,105,76,294,841,307,70,1889,2741,972,261,312,602,1476,702,2719,3090
|
1.4775738794299105,0.24745340385816628,1.4578623634759529,-0.6492423972397605,0.7786741122076469,-0.20798764245173287,-0.0694704733838678,-0.09685523182921355,-0.15209923198018688,-0.09685523182921355,0.8241310428665671,-0.17996198897025922,-0.15209923198018688,-1.000530653277979,-0.6801459566044995,1.5362117181364128,0.32349580032456454,-0.042241579625993585,1.9092431533941194,2.2376915434747073,1.0665769311873845,0.39833990773856,1.023417311456126,2.3692468623114746,-0.23617802356071166,-0.902175152364751,0.298283282312465,1.1517209730784248,1.023417311456126,0.616030896851247,0.011755338385683791,0.5205132181705904,-0.8698275055005745,-2.499432291736275
| 3,120
|
Negative regulation of mrna catabolic process
| 10
| 23
| 2.01839
| 0.043551
|
P35637,Q9Y2W1,Q14103,P67809,O60506,P07910,Q99729,Q14011,P98175,Q92804
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
248,329,615,291,517,205,342,81,426,153
|
1709,517,1433,205,1819,2912,248,291,426,2660,1936,1221,612,81,615,962,2870,1560,1752,153,342,1806,329
|
-0.15209923198018688,0.709655477037906,0.011755338385683791,1.3174933512024687,-0.20798764245173287,-1.2034112370325538,1.172767077784285,1.0665769311873845,0.8241310428665671,-0.8057719361207141,-0.2645349940023304,0.14413493056950505,0.5923317961811347,2.2042035774756688,0.5923317961811347,0.298283282312465,-1.1009154766800557,-0.042241579625993585,-0.15209923198018688,1.555594300107399,0.9579237536502591,-0.17996198897025922,0.979856683830239
| 3,120
|
Abnormal thoracic spine morphology
| 9
| 25
| 2.013399
| 0.044073
|
Q7RTS9,P02545,O00459,Q9UHX1,P08236,Q9NSE4,O95831,P51648,O75844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,376,156,397,247,344,86,91,123
|
2501,156,2878,2014,983,123,1588,86,376,1773,450,247,2460,2512,91,1548,2349,1738,32,2642,693,2363,3012,344,397
|
-0.6492423972397605,1.5362117181364128,-1.1348420125464262,-0.3217563066408477,0.2729362763877655,1.763620063558507,-0.0694704733838678,2.119398055387944,0.8915034664671595,-0.17996198897025922,0.8014574420423553,1.172767077784285,-0.6185351182463072,-0.6492423972397605,2.0677525498216016,-0.042241579625993585,-0.5275674680675104,-0.15209923198018688,3.210375491197299,-0.7740586736982547,0.5205132181705904,-0.5275674680675104,-1.5244569016571512,0.9579237536502591,0.8691530690352253
| 3,120
|
primary active transporter
| 7
| 24
| 2.00863
| 0.044576
|
P20020,P12270,Q15388,Q8N4H5,O60888,P16615,Q9NS69
|
Functions
|
Panther Protein class
|
panther_protein_class
|
377,401,294,70,109,452,261
|
109,1906,1629,1631,1249,910,401,452,377,1777,1159,2161,2108,1219,294,1224,1882,70,1889,575,2492,820,972,261
|
1.8551713497297029,-0.2645349940023304,-0.09685523182921355,-0.09685523182921355,0.11795129526109982,0.32349580032456454,0.8466959209611702,0.8014574420423553,0.8915034664671595,-0.17996198897025922,0.17017548246536693,-0.4088860728488319,-0.37966711166030426,0.14413493056950505,1.0665769311873845,0.14413493056950505,-0.23617802356071166,2.3692468623114746,-0.23617802356071166,0.6396116988763457,-0.6185351182463072,0.42302785571210444,0.298283282312465,1.1517209730784248
| 3,120
|
Emg neuropathic changes
| 7
| 26
| 2.001087
| 0.045383
|
P04792,O14773,P22626,Q13510,O43819,O95140,Q9NR77
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
128,66,321,44,239,332,126
|
2774,66,1768,239,389,332,1295,128,1339,2254,321,2398,2542,1219,44,2548,1653,2227,1558,2641,2232,1185,2794,1660,126,2372
|
-0.9675239012000673,2.385428384194839,-0.17996198897025922,1.2145771446757452,0.8691530690352253,0.9579237536502591,0.0916230653837448,1.7264856813353782,0.06514870608694326,-0.46786141367036915,0.979856683830239,-0.5576999615504026,-0.6801459566044995,0.14413493056950505,2.860509873296997,-0.6801459566044995,-0.09685523182921355,-0.4382834749199662,-0.042241579625993585,-0.7740586736982547,-0.4382834749199662,0.17017548246536693,-0.9675239012000673,-0.09685523182921355,1.763620063558507,-0.5275674680675104
| 3,120
|
Limited hip movement
| 6
| 16
| 1.998818
| 0.045628
|
P02545,Q96AY3,P06753,Q7LGA3,Q8TD16,O75844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
376,436,450,19,188,123
|
2331,123,677,376,450,2254,1487,500,19,934,188,1185,436,2000,1193,2907
|
-0.5275674680675104,1.763620063558507,0.5205132181705904,0.8915034664671595,0.8014574420423553,-0.46786141367036915,-0.015166862701093613,0.7327741710393836,3.9302356800799503,0.32349580032456454,1.4380669400587471,0.17017548246536693,0.8241310428665671,-0.29306044672954845,0.17017548246536693,-1.169006197935009
| 3,120
|
Cdc42 gtpase cycle
| 7
| 30
| 1.985585
| 0.047079
|
O00459,Q8TAA9,Q9UQB8,P02786,P42167,O75962,P42166
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
156,131,13,172,207,273,467
|
1857,156,2379,273,987,172,1820,467,207,1439,2064,1725,2517,2898,1940,1170,1046,1449,489,746,2119,1499,688,2665,131,1187,1364,757,1664,13
|
-0.23617802356071166,1.5362117181364128,-0.5576999615504026,1.1093425443192109,0.2729362763877655,1.4775738794299105,-0.20798764245173287,0.7786741122076469,1.3174933512024687,0.011755338385683791,-0.35062453129738713,-0.15209923198018688,-0.6492423972397605,-1.169006197935009,-0.2645349940023304,0.17017548246536693,0.24745340385816628,0.011755338385683791,0.75578003326324,0.47202132781882844,-0.37966711166030426,-0.015166862701093613,0.5205132181705904,-0.8057719361207141,1.7078061122023387,0.17017548246536693,0.06514870608694326,0.47202132781882844,-0.09685523182921355,4.164591374905695
| 3,120
|
Mitochondrial transmembrane transport
| 11
| 49
| 3.195098
| 0.001398
|
O75964,O43772,Q9H2D1,Q9Y4W6,O60830,O95831,O75027,P24539,O14925,P21796,P00846
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
190,7,103,201,319,13,19,82,210,304,30
|
210,1235,7,319,19,1947,661,364,190,1883,1484,1765,13,1768,30,2576,477,2276,2110,2277,304,445,82,1589,802,1597,1142,2888,2326,1294,2648,877,641,1039,885,1100,1412,1049,2894,1683,1213,1058,103,1117,712,1118,624,1271,201
|
1.2686183881470232,0.11286018680823275,4.677362749009189,1.0065013303888994,4.006603812831828,-0.27797018357638537,0.5148951741567193,0.9263931746254328,1.345837421114375,-0.2472593630138681,-0.03534902518693648,-0.18617130985484287,4.470818556597859,-0.18617130985484287,3.250151677977301,-0.6878726034160045,0.7366932011575824,-0.4646387282720388,-0.37078271612329394,-0.4646387282720388,1.0330495628348084,0.7912987450759194,2.061723178700731,-0.09535762905488879,0.40189235684510055,-0.09535762905488879,0.1714383029827371,-1.119493098438248,-0.49616131058878993,0.08342173825673257,-0.752788135498461,0.3448443594111074,0.5429225329450419,0.22962386216876518,0.3448443594111074,0.2005797220728047,0.024241586061113263,0.22962386216876518,-1.119493098438248,-0.1255210940747614,0.14219874771718682,0.22962386216876518,1.9178936975445875,0.2005797220728047,0.4867792187177262,0.2005797220728047,0.5708620218746475,0.11286018680823275,1.3201682686463994
| 3,120
|
transporter
| 11
| 55
| 3.030302
| 0.002443
|
Q567V2,Q6N075,Q9C0E2,O43772,Q9H2D1,Q9NR77,Q15070,P41440,Q99805,P53985,O00629
|
Functions
|
Panther Protein class
|
panther_protein_class
|
0,97,70,7,103,15,79,48,148,89,125
|
1943,2162,125,2960,2572,1076,1235,2208,7,319,1583,2459,498,545,48,2466,909,607,2468,1664,2888,89,947,2426,2427,731,2889,1353,2074,79,0,97,2081,1042,431,845,1002,473,779,1517,434,1746,968,148,2252,2833,70,103,2256,208,15,1527,2722,1271,2972
|
-0.27797018357638537,-0.4019505979654591,1.6733543531428043,-1.3269099832801567,-0.6878726034160045,0.2005797220728047,0.11286018680823275,-0.4332355494784209,4.677362749009189,1.0065013303888994,-0.09535762905488879,-0.5914575294331794,0.7092661942106616,0.6541603945159422,2.6843950264914866,-0.5914575294331794,0.3161810009783176,0.5708620218746475,-0.5914575294331794,-0.1255210940747614,-1.119493098438248,2.014013969891034,0.28742367409721314,-0.5595694864386637,-0.5595694864386637,0.4585739300606462,-1.119493098438248,0.05388250728134245,-0.3397307645692643,2.0854913469354517,7.381862894827085,1.966071809474578,-0.3397307645692643,0.22962386216876518,0.8184785830912821,0.37341454860880774,0.25857156840411794,0.7640371665537453,0.4302785616599747,-0.03534902518693648,0.8184785830912821,-0.15579198537738093,0.28742367409721314,1.5235928835204335,-0.4332355494784209,-0.9841905255516471,2.320088204991794,1.9178936975445875,-0.4332355494784209,1.2944287599319277,4.356553869657722,-0.03534902518693648,-0.8182272955248096,0.11286018680823275,-1.3269099832801567
| 3,120
|
Negative regulation of mrna metabolic process
| 25
| 45
| 2.989021
| 0.002799
|
P98175,Q92804,Q9Y2W1,P26368,O00267,P61978,O75494,P07910,O60506,Q14103,Q08170,Q07021,P35637,Q13242,P67809,Q14011,P22626,Q13151,Q6PD62,O75150,Q6PJT7,Q99729,P50750,Q16629,P38159
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
249,136,272,767,758,278,519,276,273,413,671,411,288,184,195,68,200,694,742,461,484,224,729,367,120
|
1761,758,1385,273,461,519,1642,276,2052,2818,2728,200,767,1288,288,120,729,278,195,249,2513,411,671,1722,1724,1963,694,184,807,68,413,2132,1409,2240,367,998,742,484,1463,1564,136,224,1215,1754,272
|
-0.18617130985484287,0.4302785616599747,0.024241586061113263,1.0859177757996075,0.7640371665537453,0.6817554825782532,-0.1255210940747614,1.0859177757996075,-0.3397307645692643,-0.9841905255516471,-0.851146720270504,1.3201682686463994,0.4302785616599747,0.08342173825673257,1.0595215210565851,1.722759492295663,0.4585739300606462,1.0859177757996075,1.345837421114375,1.1646579241278294,-0.6234698757692442,0.8455773188024565,0.5148951741567193,-0.15579198537738093,-0.15579198537738093,-0.27797018357638537,0.4867792187177262,1.3714367183211587,0.40189235684510055,2.3432469391311894,0.8455773188024565,-0.37078271612329394,0.024241586061113263,-0.4332355494784209,0.9263931746254328,0.25857156840411794,0.4585739300606462,0.7366932011575824,-0.005501946528574578,-0.06530059846579093,1.6236938729897266,1.2427366405346731,0.14219874771718682,-0.15579198537738093,1.112238890931671
| 3,120
|
Endopeptidase activity
| 21
| 58
| 2.836639
| 0.004559
|
Q9NZ08,Q16740,Q99436,P20618,Q8TEY7,O14773,P28070,P22695,Q92542,Q4J6C6,Q9BYT8,Q9H300,Q10713,Q9Y4W6,Q5JRX3,P49721,O43847,Q96K76,Q96E52,O75844,P42892
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
146,16,147,394,162,157,164,406,432,170,61,458,67,201,467,83,219,223,100,98,227
|
157,2408,219,1947,98,1771,2366,2278,666,394,406,2962,164,565,543,2170,2321,1497,227,2010,2544,1661,83,1780,911,1781,2371,1602,67,2514,2946,2131,16,170,467,2294,1043,2848,162,432,780,2443,2249,1160,100,223,489,751,147,2658,1684,61,458,146,2355,1633,1424,201
|
1.4731451750207736,-0.5595694864386637,1.2427366405346731,-0.27797018357638537,1.9420124373826877,-0.18617130985484287,-0.527804491720768,-0.4646387282720388,0.5148951741567193,0.8725955823893464,0.8455773188024565,-1.3269099832801567,1.44782040257826,0.6264802495143728,0.6541603945159422,-0.4019505979654591,-0.49616131058878993,-0.03534902518693648,1.2167829983083687,-0.3087936217536729,-0.655607801353578,-0.1255210940747614,2.061723178700731,-0.18617130985484287,0.3161810009783176,-0.18617130985484287,-0.527804491720768,-0.09535762905488879,2.3432469391311894,-0.6234698757692442,-1.2571576219277842,-0.37078271612329394,4.3182069370435086,1.4224277222525785,0.7640371665537453,-0.4646387282720388,0.22962386216876518,-1.0178005054933905,1.4731451750207736,0.8184785830912821,0.4302785616599747,-0.5595694864386637,-0.4332355494784209,0.1714383029827371,1.9420124373826877,1.2427366405346731,0.7366932011575824,0.4585739300606462,1.5235928835204335,-0.752788135498461,-0.1255210940747614,2.4810892168331504,0.7912987450759194,1.5487167500155263,-0.49616131058878993,-0.09535762905488879,0.024241586061113263,1.3201682686463994
| 3,120
|
Unsteady gait
| 8
| 50
| 2.772111
| 0.005569
|
Q10713,O75503,Q96F07,O95831,Q9NR77,Q9H6K4,Q15907,P07196
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
67,74,139,13,15,117,22,27
|
936,937,74,903,1483,1486,13,27,3066,2697,1285,1545,2503,1899,2115,2325,606,2174,2871,1187,2673,3054,1246,1552,609,2477,67,2017,2377,1909,2291,1674,22,467,918,1258,2930,843,2246,1263,2394,139,1013,117,2881,15,1170,1018,174,1991
|
0.28742367409721314,0.28742367409721314,2.25028838869321,0.3161810009783176,-0.03534902518693648,-0.03534902518693648,4.470818556597859,3.271312628477843,-1.9469976827898703,-0.8182272955248096,0.08342173825673257,-0.06530059846579093,-0.6234698757692442,-0.2472593630138681,-0.37078271612329394,-0.49616131058878993,0.5708620218746475,-0.4019505979654591,-1.0854501809743031,0.14219874771718682,-0.7854415711286908,-1.8337922669505038,0.11286018680823275,-0.06530059846579093,0.5708620218746475,-0.5914575294331794,2.3432469391311894,-0.3087936217536729,-0.527804491720768,-0.2472593630138681,-0.4646387282720388,-0.1255210940747614,3.3974000867373655,0.7640371665537453,0.3161810009783176,0.11286018680823275,-1.1880233702760612,0.37341454860880774,-0.4332355494784209,0.11286018680823275,-0.527804491720768,1.5737745696657581,0.25857156840411794,1.7963958694618998,-1.0854501809743031,4.356553869657722,0.1714383029827371,0.25857156840411794,1.4224277222525785,-0.27797018357638537
| 3,120
|
Intrinsic component of mitochondrial membrane
| 18
| 46
| 2.64615
| 0.008141
|
Q9Y2R0,P57105,Q16134,O43819,Q53H12,Q5XKP0,Q9Y6N1,Q9Y4W6,O60830,Q9GZY8,Q9H9B4,Q13505,Q15070,O75431,O95140,Q9BWH2,Q16891,O14925
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,247,449,131,482,382,265,201,319,207,712,78,79,577,601,516,507,210
|
210,131,319,577,2665,1883,601,1765,1768,2110,2058,1086,1142,247,2648,78,79,877,449,507,482,382,1039,1915,2297,1100,1973,2894,1683,1213,1418,1983,516,207,1986,712,713,2716,823,855,824,1017,1,201,1071,265
|
1.2686183881470232,1.6485562465385502,1.0065013303888994,0.5987143581404145,-0.7854415711286908,-0.2472593630138681,0.5708620218746475,-0.18617130985484287,-0.18617130985484287,-0.37078271612329394,-0.3397307645692643,0.2005797220728047,0.1714383029827371,1.1646579241278294,-0.752788135498461,2.0854913469354517,2.0854913469354517,0.3448443594111074,0.7912987450759194,0.7092661942106616,0.7366932011575824,0.8995339961478345,0.22962386216876518,-0.2472593630138681,-0.4646387282720388,0.2005797220728047,-0.27797018357638537,-1.119493098438248,-0.1255210940747614,0.14219874771718682,0.024241586061113263,-0.27797018357638537,0.7092661942106616,1.2944287599319277,-0.27797018357638537,0.4867792187177262,0.4867792187177262,-0.8182272955248096,0.40189235684510055,0.37341454860880774,0.40189235684510055,0.25857156840411794,6.770573110173742,1.3201682686463994,0.22962386216876518,1.1384854235569977
| 3,120
|
Regulation of mrna splicing via spliceosome
| 27
| 62
| 2.615213
| 0.008917
|
P98175,Q9Y2W1,P98179,P61978,O75494,Q08170,Q07021,P62995,P19338,P51114,Q13242,Q07666,Q9Y580,P52756,Q14011,P22626,Q15427,Q15007,Q13595,Q9UHX1,Q13573,P51116,Q16629,Q96MU7,Q9BWF3,P38159,Q9H0G5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
249,272,20,278,519,671,411,409,287,290,184,693,199,194,68,200,697,214,213,234,610,229,367,114,515,120,653
|
1385,519,1486,940,1239,1649,2997,1953,1345,287,200,767,1288,2784,2636,120,1445,290,229,194,1664,278,409,1089,249,20,2513,411,693,671,2126,1724,184,807,610,213,68,1793,214,2132,697,698,367,880,2738,2187,1411,1799,2893,1567,114,1007,2251,1373,1215,515,653,234,2040,272,199,2205
|
0.024241586061113263,0.6817554825782532,-0.03534902518693648,0.28742367409721314,0.11286018680823275,-0.1255210940747614,-1.432729732702481,-0.27797018357638537,0.05388250728134245,1.0595215210565851,1.3201682686463994,0.4302785616599747,0.08342173825673257,-0.9173924403878517,-0.752788135498461,1.722759492295663,-0.005501946528574578,1.0595215210565851,1.2167829983083687,1.345837421114375,-0.1255210940747614,1.0859177757996075,0.8455773188024565,0.2005797220728047,1.1646579241278294,3.7265538961328755,-0.6234698757692442,0.8455773188024565,0.4867792187177262,0.5148951741567193,-0.37078271612329394,-0.15579198537738093,1.3714367183211587,0.40189235684510055,0.5708620218746475,1.2686183881470232,2.3432469391311894,-0.18617130985484287,1.2686183881470232,-0.37078271612329394,0.4867792187177262,0.4867792187177262,0.9263931746254328,0.3448443594111074,-0.851146720270504,-0.4019505979654591,0.024241586061113263,-0.18617130985484287,-1.119493098438248,-0.06530059846579093,1.820817302664816,0.25857156840411794,-0.4332355494784209,0.05388250728134245,0.14219874771718682,0.7092661942106616,0.5429225329450419,1.2167829983083687,-0.3087936217536729,1.112238890931671,1.345837421114375,-0.4019505979654591
| 3,120
|
Phospholipid metabolism
| 16
| 47
| 2.529567
| 0.01142
|
Q8IY17,Q8TBX8,Q96N66,Q10713,Q53H12,Q8NCC3,Q8IV08,Q9NPH0,Q9NQZ5,Q8N335,Q9BVG9,O00459,Q6UWP7,P35790,Q8N2A8,P42356
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
387,66,296,67,482,6,531,10,107,145,343,109,398,142,339,365
|
2455,109,2603,3034,2495,1766,2050,1653,1084,1654,142,2284,365,632,3103,2466,2641,1782,1504,914,67,482,398,2186,531,387,339,145,1514,6,552,66,1977,296,1925,2657,1684,2396,2254,343,822,10,107,2352,2719,1573,824
|
-0.5914575294331794,1.8694765711925077,-0.7202656010050781,-1.6854776623463188,-0.6234698757692442,-0.18617130985484287,-0.3397307645692643,-0.1255210940747614,0.2005797220728047,-0.1255210940747614,1.5487167500155263,-0.4646387282720388,0.9263931746254328,0.5429225329450419,-2.9230255048313363,-0.5914575294331794,-0.752788135498461,-0.18617130985484287,-0.03534902518693648,0.3161810009783176,2.3432469391311894,0.7366932011575824,0.8725955823893464,-0.4019505979654591,0.6817554825782532,0.8995339961478345,0.9798762459794423,1.5487167500155263,-0.03534902518693648,4.806885400992172,0.6541603945159422,2.3663522803788886,-0.27797018357638537,1.0595215210565851,-0.2472593630138681,-0.752788135498461,-0.1255210940747614,-0.527804491720768,-0.4332355494784209,0.9798762459794423,0.40189235684510055,4.621402390679723,1.8937152051140331,-0.49616131058878993,-0.8182272955248096,-0.06530059846579093,0.40189235684510055
| 3,120
|
Ion transport
| 22
| 55
| 2.520795
| 0.011709
|
Q14847,Q9UM00,Q8TDW0,P00846,Q9Y487,P05026,P35670,Q9Y277,P21796,Q93050,P36543,O75964,Q15904,P16615,P24539,Q6N075,Q4KMQ2,P20020,P06576,Q6P4Q7,Q04656,O75947
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
381,538,416,30,166,663,544,53,304,62,192,190,448,333,82,97,612,349,477,483,609,364
|
2359,364,190,1484,1768,30,1705,663,477,1708,333,349,1346,667,304,906,82,1589,544,802,192,1899,908,1597,2505,2470,2425,2326,1294,2645,1192,609,381,2845,448,612,97,483,2081,1205,1100,745,416,62,2894,1213,1623,1014,2094,1695,538,53,166,2987,1636
|
-0.527804491720768,0.9263931746254328,1.345837421114375,-0.03534902518693648,-0.18617130985484287,3.250151677977301,-0.15579198537738093,0.5148951741567193,0.7366932011575824,-0.15579198537738093,0.9798762459794423,0.9531737247539802,0.05388250728134245,0.5148951741567193,1.0330495628348084,0.3161810009783176,2.061723178700731,-0.09535762905488879,0.6541603945159422,0.40189235684510055,1.345837421114375,-0.2472593630138681,0.3161810009783176,-0.09535762905488879,-0.6234698757692442,-0.5914575294331794,-0.5595694864386637,-0.49616131058878993,0.08342173825673257,-0.752788135498461,0.14219874771718682,0.5708620218746475,0.8995339961478345,-1.0178005054933905,0.7912987450759194,0.5708620218746475,1.966071809474578,0.7366932011575824,-0.3397307645692643,0.14219874771718682,0.2005797220728047,0.4585739300606462,0.8455773188024565,2.4582460880874186,-1.119493098438248,0.14219874771718682,-0.09535762905488879,0.25857156840411794,-0.3397307645692643,-0.1255210940747614,0.6817554825782532,2.6620048510442116,1.44782040257826,-1.3620225182786942,-0.09535762905488879
| 3,120
|
Slowly progressive
| 22
| 58
| 2.510216
| 0.012066
|
Q8IV08,P04792,O95831,Q15120,Q9NR77,Q5T440,Q92734,P07196,O14773,Q99720,P50402,P51530,P41440,O14979,Q9P0J0,Q9Y6X9,Q9Y3I1,Q9Y4W6,O95140,Q04656,O75340,Q5JTV8
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
531,628,13,638,15,674,417,27,157,35,289,168,48,176,198,460,596,201,601,609,363,508
|
1230,2360,157,176,1534,1390,363,1483,1393,601,13,662,628,1705,27,2110,3036,2856,2636,1347,2056,2115,48,2117,1186,289,2061,168,1244,2064,2548,609,2017,838,2237,2238,1792,638,1035,508,674,918,1258,531,1513,1972,417,2087,3081,35,820,15,1524,198,2489,596,201,460
|
0.11286018680823275,-0.527804491720768,1.4731451750207736,1.3969666555059603,-0.06530059846579093,0.024241586061113263,0.9263931746254328,-0.03534902518693648,0.024241586061113263,0.5708620218746475,4.470818556597859,0.5148951741567193,0.5429225329450419,-0.15579198537738093,3.271312628477843,-0.37078271612329394,-1.6854776623463188,-1.0515531918290377,-0.752788135498461,0.05388250728134245,-0.3397307645692643,-0.37078271612329394,2.6843950264914866,-0.37078271612329394,0.14219874771718682,1.0595215210565851,-0.3397307645692643,1.4224277222525785,0.11286018680823275,-0.3397307645692643,-0.655607801353578,0.5708620218746475,-0.3087936217536729,0.37341454860880774,-0.4332355494784209,-0.4332355494784209,-0.18617130985484287,0.5429225329450419,0.22962386216876518,0.7092661942106616,0.5148951741567193,0.3161810009783176,0.11286018680823275,0.6817554825782532,-0.03534902518693648,-0.27797018357638537,0.8455773188024565,-0.3397307645692643,-2.1396308403876003,3.014532465180862,0.40189235684510055,4.356553869657722,-0.03534902518693648,1.345837421114375,-0.5914575294331794,0.5987143581404145,1.3201682686463994,0.7912987450759194
| 3,120
|
Retinal degeneration
| 9
| 54
| 2.428522
| 0.015161
|
O14773,Q10713,Q7LGA3,P51648,Q96F07,O75503,P50897,O75648,Q13510
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
157,67,9,41,139,74,124,220,60
|
2838,157,1578,226,1823,74,1133,220,1486,2605,662,1769,1396,2318,1834,2007,2781,2584,2417,1547,1899,2325,2174,2060,124,41,2807,2425,1246,2430,1552,2477,67,60,1852,2335,9,1201,387,678,2246,1974,1307,1003,139,572,2027,1013,652,972,2628,929,824,1991
|
-1.0178005054933905,1.4731451750207736,-0.09535762905488879,1.2167829983083687,-0.21666008975636944,2.25028838869321,0.1714383029827371,1.2427366405346731,-0.03534902518693648,-0.7202656010050781,0.5148951741567193,-0.18617130985484287,0.024241586061113263,-0.49616131058878993,-0.21666008975636944,-0.3087936217536729,-0.9173924403878517,-0.6878726034160045,-0.5595694864386637,-0.06530059846579093,-0.2472593630138681,-0.49616131058878993,-0.4019505979654591,-0.3397307645692643,1.6980886256713434,2.8617795288788566,-0.9507216839667448,-0.5595694864386637,0.11286018680823275,-0.5595694864386637,-0.06530059846579093,-0.5914575294331794,2.3432469391311894,2.526621237286272,-0.21666008975636944,-0.49616131058878993,4.658739680122686,0.14219874771718682,0.8995339961478345,0.5148951741567193,-0.4332355494784209,-0.27797018357638537,0.08342173825673257,0.25857156840411794,1.5737745696657581,0.6264802495143728,-0.3087936217536729,0.25857156840411794,0.5429225329450419,0.28742367409721314,-0.7202656010050781,0.3161810009783176,0.40189235684510055,-0.27797018357638537
| 3,120
|
Cation transmembrane transporter activity
| 30
| 75
| 2.407005
| 0.016084
|
P20674,O43772,Q9UM00,P13073,Q9UDW1,Q93034,P00846,Q9Y487,P05026,P21283,P35670,Q93050,P36543,O14548,Q70HW3,O75964,P00403,Q8N4V1,P16615,P24539,P30825,Q7KZN9,Q4KMQ2,P20020,P06576,Q6P4Q7,Q04656,O75947,Q13423,Q9HD20
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
379,7,538,26,29,555,30,166,663,667,544,62,192,189,69,190,441,340,333,82,94,384,612,349,477,483,609,364,118,258
|
189,7,1537,364,190,1484,441,30,1705,663,2576,477,797,1082,1543,939,1707,2667,2110,26,333,349,379,1346,667,906,82,1589,94,2700,544,802,192,1899,2788,1597,2505,2425,2326,1294,2645,2889,1192,2648,2927,609,118,2845,1300,612,483,2081,69,384,340,1100,745,1977,555,62,1683,2252,1569,1376,2094,1117,712,2716,258,929,29,1695,538,166,1636
|
1.345837421114375,4.677362749009189,-0.06530059846579093,0.9263931746254328,1.345837421114375,-0.03534902518693648,0.7912987450759194,3.250151677977301,-0.15579198537738093,0.5148951741567193,-0.6878726034160045,0.7366932011575824,0.40189235684510055,0.2005797220728047,-0.06530059846579093,0.28742367409721314,-0.15579198537738093,-0.7854415711286908,-0.37078271612329394,3.292431395300117,0.9798762459794423,0.9531737247539802,0.8995339961478345,0.05388250728134245,0.5148951741567193,0.3161810009783176,2.061723178700731,-0.09535762905488879,1.9900721946723605,-0.8182272955248096,0.6541603945159422,0.40189235684510055,1.345837421114375,-0.2472593630138681,-0.9173924403878517,-0.09535762905488879,-0.6234698757692442,-0.5595694864386637,-0.49616131058878993,0.08342173825673257,-0.752788135498461,-1.119493098438248,0.14219874771718682,-0.752788135498461,-1.1880233702760612,0.5708620218746475,1.7719126974504582,-1.0178005054933905,0.08342173825673257,0.5708620218746475,0.7366932011575824,-0.3397307645692643,2.3432469391311894,0.8995339961478345,0.9798762459794423,0.2005797220728047,0.4585739300606462,-0.27797018357638537,0.6541603945159422,2.4582460880874186,-0.1255210940747614,-0.4332355494784209,-0.06530059846579093,0.05388250728134245,-0.3397307645692643,0.2005797220728047,0.4867792187177262,-0.8182272955248096,1.1646579241278294,0.3161810009783176,3.271312628477843,-0.1255210940747614,0.6817554825782532,1.44782040257826,-0.09535762905488879
| 3,120
|
SLC superfamily of solute carriers
| 7
| 44
| 2.374674
| 0.017564
|
Q6N075,Q70HW3,O43772,Q8IXU6,P41440,P53985,P30825
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
97,69,7,72,48,89,94
|
7,1537,661,1484,1765,2576,939,3066,2110,2277,94,48,2888,89,2425,2648,2553,2845,1300,97,1678,2439,2081,69,72,745,1102,1977,1683,2252,1058,1569,1376,103,2094,1117,712,2716,2259,2721,420,624,1228,1636
|
4.677362749009189,-0.06530059846579093,0.5148951741567193,-0.03534902518693648,-0.18617130985484287,-0.6878726034160045,0.28742367409721314,-1.9469976827898703,-0.37078271612329394,-0.4646387282720388,1.9900721946723605,2.6843950264914866,-1.119493098438248,2.014013969891034,-0.5595694864386637,-0.752788135498461,-0.655607801353578,-1.0178005054933905,0.08342173825673257,1.966071809474578,-0.1255210940747614,-0.5595694864386637,-0.3397307645692643,2.3432469391311894,2.296875753908948,0.4585739300606462,0.2005797220728047,-0.27797018357638537,-0.1255210940747614,-0.4332355494784209,0.22962386216876518,-0.06530059846579093,0.05388250728134245,1.9178936975445875,-0.3397307645692643,0.2005797220728047,0.4867792187177262,-0.8182272955248096,-0.4332355494784209,-0.8182272955248096,0.8455773188024565,0.5708620218746475,0.14219874771718682,-0.09535762905488879
| 3,120
|
Glycoprotein biosynthetic process
| 14
| 51
| 2.354748
| 0.018535
|
Q10471,Q10472,Q7LGA3,O60502,O43505,Q96L58,Q9H6U8,O15118,Q99805,Q96JB2,O75340,Q8NCH0,Q08379,Q9NY61
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
412,212,9,73,43,370,244,361,148,52,363,154,306,299
|
2161,361,1482,43,1236,73,1429,1130,2043,363,2536,764,1135,3011,1547,2282,803,2587,1403,2617,2015,609,1962,306,412,212,3069,1727,874,2651,1097,9,2653,2387,154,1515,432,52,370,1057,148,2143,2918,1376,1377,2447,244,972,299,715,2567
|
-0.4019505979654591,0.9263931746254328,-0.03534902518693648,2.7290289921712847,0.11286018680823275,2.2736092586370935,-0.005501946528574578,0.1714383029827371,-0.3397307645692643,0.9263931746254328,-0.655607801353578,0.4302785616599747,0.1714383029827371,-1.468328297108414,-0.06530059846579093,-0.4646387282720388,0.40189235684510055,-0.6878726034160045,0.024241586061113263,-0.7202656010050781,-0.3087936217536729,0.5708620218746475,-0.27797018357638537,1.0330495628348084,0.8455773188024565,1.2686183881470232,-1.9469976827898703,-0.15579198537738093,0.3448443594111074,-0.752788135498461,0.2005797220728047,4.658739680122686,-0.752788135498461,-0.527804491720768,1.4984025127237648,-0.03534902518693648,0.8184785830912821,2.6620048510442116,0.9263931746254328,0.22962386216876518,1.5235928835204335,-0.37078271612329394,-1.1536835995610857,0.05388250728134245,0.05388250728134245,-0.5595694864386637,1.1907569365536894,0.28742367409721314,1.0595215210565851,0.4867792187177262,-0.655607801353578
| 3,120
|
Lower limb muscle weakness
| 18
| 44
| 2.282961
| 0.022433
|
Q8IY17,Q9Y6X9,O43819,P02545,O75298,Q9Y4W6,O95140,P04792,P37198,Q9NR77,Q15120,Q8N0X7,Q5T440,Q92734,P07196,Q13510,P00846,Q15149
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
387,460,131,662,346,201,601,628,545,15,638,369,674,417,27,60,30,673
|
1533,131,346,1393,601,30,662,628,982,27,1771,2276,1834,2008,1085,545,2284,2115,2888,2064,2508,2641,2120,2706,2017,806,60,2072,838,2238,638,673,674,1365,387,369,1972,417,887,1105,706,15,201,460
|
-0.06530059846579093,1.6485562465385502,0.9531737247539802,0.024241586061113263,0.5708620218746475,3.250151677977301,0.5148951741567193,0.5429225329450419,0.25857156840411794,3.271312628477843,-0.18617130985484287,-0.4646387282720388,-0.21666008975636944,-0.3087936217536729,0.2005797220728047,0.6541603945159422,-0.4646387282720388,-0.37078271612329394,-1.119493098438248,-0.3397307645692643,-0.6234698757692442,-0.752788135498461,-0.37078271612329394,-0.8182272955248096,-0.3087936217536729,0.40189235684510055,2.526621237286272,-0.3397307645692643,0.37341454860880774,-0.4332355494784209,0.5429225329450419,0.5148951741567193,0.5148951741567193,0.05388250728134245,0.8995339961478345,0.9263931746254328,-0.27797018357638537,0.8455773188024565,0.3448443594111074,0.2005797220728047,0.4867792187177262,4.356553869657722,1.3201682686463994,0.7912987450759194
| 3,120
|
Talipes equinovarus
| 28
| 80
| 2.248752
| 0.024528
|
P98175,O75845,P08236,Q9HD42,Q9UM00,Q6NUQ1,Q9NR77,P04792,Q15907,P61978,Q8NCH0,O96028,P21964,Q15392,Q9Y487,Q7RTS9,Q9UJX6,Q96MW5,P36543,Q9Y3I1,Q8NI60,Q8TAA9,Q8TD16,Q96L58,Q9H6U8,P42356,Q96AY3,Q9H9E3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
249,2,495,537,538,529,15,628,22,278,154,274,159,31,166,45,316,592,192,596,472,215,221,370,244,365,648,392
|
2161,2266,2102,2801,937,1429,1764,1581,2,2049,1484,274,628,982,495,2317,1651,1834,2461,159,1775,192,1899,2422,365,1598,1902,1187,1958,2064,278,249,635,2015,1961,2017,2433,875,31,697,22,881,529,1200,1097,45,2393,154,1466,1972,472,215,1973,221,2137,1467,1105,748,648,370,1006,592,2918,1015,244,2399,392,2716,537,15,2036,316,1381,538,2096,900,596,166,2205,2995
|
-0.4019505979654591,-0.4646387282720388,-0.37078271612329394,-0.9507216839667448,0.28742367409721314,-0.005501946528574578,-0.18617130985484287,-0.09535762905488879,6.275849522245003,-0.3397307645692643,-0.03534902518693648,1.0859177757996075,0.5429225329450419,0.25857156840411794,0.7092661942106616,-0.49616131058878993,-0.1255210940747614,-0.21666008975636944,-0.5914575294331794,1.4731451750207736,-0.18617130985484287,1.345837421114375,-0.2472593630138681,-0.5595694864386637,0.9263931746254328,-0.09535762905488879,-0.2472593630138681,0.14219874771718682,-0.27797018357638537,-0.3397307645692643,1.0859177757996075,1.1646579241278294,0.5429225329450419,-0.3087936217536729,-0.27797018357638537,-0.3087936217536729,-0.5595694864386637,0.3448443594111074,3.207702339311733,0.4867792187177262,3.3974000867373655,0.3448443594111074,0.6817554825782532,0.14219874771718682,0.2005797220728047,2.7290289921712847,-0.527804491720768,1.4984025127237648,-0.005501946528574578,-0.27797018357638537,0.7640371665537453,1.2686183881470232,-0.27797018357638537,1.2427366405346731,-0.37078271612329394,-0.005501946528574578,0.2005797220728047,0.4585739300606462,0.5429225329450419,0.9263931746254328,0.25857156840411794,0.5987143581404145,-1.1536835995610857,0.25857156840411794,1.1907569365536894,-0.527804491720768,0.8995339961478345,-0.8182272955248096,0.6817554825782532,4.356553869657722,-0.3087936217536729,1.0330495628348084,0.05388250728134245,0.6817554825782532,-0.3397307645692643,0.3448443594111074,0.5987143581404145,1.44782040257826,-0.4019505979654591,-1.3972951268692342
| 3,120
|
Bowing of the legs
| 14
| 49
| 2.23045
| 0.025718
|
P08236,O75718,Q15056,Q7LGA3,Q13126,Q7RTS9,Q96HY6,Q9NR77,Q32P28,O75431,Q96L58,Q8N0X7,Q04656,Q9NX62
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
495,347,480,9,240,45,401,15,144,577,370,369,609,359
|
2161,2310,2165,1764,577,347,1180,495,2867,799,1651,1831,2461,1085,2054,2420,2369,1497,1349,1449,635,914,2431,609,1196,240,1558,480,1854,144,9,45,2385,369,1466,2137,401,370,1006,2093,15,1809,2852,359,2155,1381,2489,1760,2205
|
-0.4019505979654591,-0.49616131058878993,-0.4019505979654591,-0.18617130985484287,0.5987143581404145,0.9531737247539802,0.14219874771718682,0.7092661942106616,-1.0854501809743031,0.40189235684510055,-0.1255210940747614,-0.21666008975636944,-0.5914575294331794,0.2005797220728047,-0.3397307645692643,-0.5595694864386637,-0.527804491720768,-0.03534902518693648,0.05388250728134245,-0.005501946528574578,0.5429225329450419,0.3161810009783176,-0.5595694864386637,0.5708620218746475,0.14219874771718682,1.1907569365536894,-0.06530059846579093,0.7366932011575824,-0.21666008975636944,1.5487167500155263,4.658739680122686,2.7290289921712847,-0.527804491720768,0.9263931746254328,-0.005501946528574578,-0.37078271612329394,0.8725955823893464,0.9263931746254328,0.25857156840411794,-0.3397307645692643,4.356553869657722,-0.18617130985484287,-1.0178005054933905,0.9531737247539802,-0.37078271612329394,0.05388250728134245,-0.5914575294331794,-0.15579198537738093,-0.4019505979654591
| 3,120
|
Abnormal femoral neck head morphology
| 17
| 45
| 2.216217
| 0.026677
|
Q96MW5,Q9Y487,P51812,P04066,Q14739,O75844,Q7LGA3,O75718,O95831,Q6NUQ1,Q96HY6,Q7RTS9,O75431,Q96L58,Q04656,Q96AY3,Q9H9E3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
592,166,634,378,611,98,9,347,13,529,401,45,577,370,609,648,392
|
2455,1429,1764,577,1581,347,98,13,662,378,799,2461,2054,1775,2058,2638,1837,634,2425,1447,609,611,1558,1251,996,529,1916,9,45,2385,748,648,401,370,592,2983,1063,392,2798,2852,1381,2096,1995,166,2205
|
-0.5914575294331794,-0.005501946528574578,-0.18617130985484287,0.5987143581404145,-0.09535762905488879,0.9531737247539802,1.9420124373826877,4.470818556597859,0.5148951741567193,0.8995339961478345,0.40189235684510055,-0.5914575294331794,-0.3397307645692643,-0.18617130985484287,-0.3397307645692643,-0.752788135498461,-0.21666008975636944,0.5429225329450419,-0.5595694864386637,-0.005501946528574578,0.5708620218746475,0.5708620218746475,-0.06530059846579093,0.11286018680823275,0.25857156840411794,0.6817554825782532,-0.2472593630138681,4.658739680122686,2.7290289921712847,-0.527804491720768,0.4585739300606462,0.5429225329450419,0.8725955823893464,0.9263931746254328,0.5987143581404145,-1.3620225182786942,0.22962386216876518,0.8995339961478345,-0.9173924403878517,-1.0178005054933905,0.05388250728134245,-0.3397307645692643,-0.27797018357638537,1.44782040257826,-0.4019505979654591
| 3,120
|
Abnormality of the larynx
| 19
| 48
| 2.215788
| 0.026706
|
Q92804,Q01082,Q96HY6,Q13501,P21964,P02545,P35637,Q9UQN3,Q9UHD9,Q13510,Q9H0U9,Q15165,P36543,Q69YQ0,Q99700,Q9UHX1,Q14739,Q9UBM7,P43243
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
136,635,401,268,159,662,288,175,573,60,457,64,192,77,620,234,611,373,606
|
1426,1533,2102,1764,1703,2050,662,2213,3044,1239,1651,2461,159,2367,2906,288,192,1497,2422,606,946,2424,2062,1958,2508,635,1963,268,60,838,611,1558,64,697,77,2385,1466,1048,136,1467,401,620,457,2721,373,573,234,175
|
-0.005501946528574578,-0.06530059846579093,-0.37078271612329394,-0.18617130985484287,-0.15579198537738093,-0.3397307645692643,0.5148951741567193,-0.4332355494784209,-1.7592679631428478,0.11286018680823275,-0.1255210940747614,-0.5914575294331794,1.4731451750207736,-0.527804491720768,-1.1536835995610857,1.0595215210565851,1.345837421114375,-0.03534902518693648,-0.5595694864386637,0.5708620218746475,0.28742367409721314,-0.5595694864386637,-0.3397307645692643,-0.27797018357638537,-0.6234698757692442,0.5429225329450419,-0.27797018357638537,1.112238890931671,2.526621237286272,0.37341454860880774,0.5708620218746475,-0.06530059846579093,2.435351140278348,0.4867792187177262,2.1092023745855184,-0.527804491720768,-0.005501946528574578,0.22962386216876518,1.6236938729897266,-0.005501946528574578,0.8725955823893464,0.5708620218746475,0.7912987450759194,-0.8182272955248096,0.9263931746254328,0.6264802495143728,1.2167829983083687,1.4224277222525785
| 3,120
|
Action tremor
| 9
| 55
| 2.21529
| 0.02674
|
O14773,Q99720,Q9NR77,P41440,O75027,Q8NC56,Q9H6K4,Q14108,P00846
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
157,35,15,48,19,51,117,121,30
|
2691,157,1426,1534,2208,19,2045,903,1483,601,1703,30,3085,2903,1888,1950,2007,1652,463,1588,2417,2056,288,48,1242,1662,989,2228,2064,635,121,876,467,918,3013,2828,387,1513,51,2982,3081,620,35,1418,117,2601,1220,15,929,2721,1170,1991,1226,596,201
|
-0.8182272955248096,1.4731451750207736,-0.005501946528574578,-0.06530059846579093,-0.4332355494784209,4.006603812831828,-0.3397307645692643,0.3161810009783176,-0.03534902518693648,0.5708620218746475,-0.15579198537738093,3.250151677977301,-2.2975016585472585,-1.1536835995610857,-0.2472593630138681,-0.27797018357638537,-0.3087936217536729,-0.1255210940747614,0.7640371665537453,-0.09535762905488879,-0.5595694864386637,-0.3397307645692643,1.0595215210565851,2.6843950264914866,0.11286018680823275,-0.1255210940747614,0.25857156840411794,-0.4332355494784209,-0.3397307645692643,0.5429225329450419,1.722759492295663,0.3448443594111074,0.7640371665537453,0.3161810009783176,-1.468328297108414,-0.9841905255516471,0.8995339961478345,-0.03534902518693648,2.6620048510442116,-1.3620225182786942,-2.1396308403876003,0.5708620218746475,3.014532465180862,0.024241586061113263,1.7963958694618998,-0.6878726034160045,0.14219874771718682,4.356553869657722,0.3161810009783176,-0.8182272955248096,0.1714383029827371,-0.27797018357638537,0.14219874771718682,0.5987143581404145,1.3201682686463994
| 3,120
|
Regulation of rna splicing
| 41
| 86
| 2.179188
| 0.029318
|
P98175,Q9Y2W1,O60828,Q8WVV9,P98179,P61978,Q9NW64,O75494,Q08170,Q07021,P62995,P35637,P19338,P51114,Q09666,P52597,Q13242,P55795,Q07666,Q9Y580,P52756,Q14011,P22626,Q07955,P31942,Q15427,Q15637,Q15007,Q8IXT5,Q13595,Q9UHX1,Q13573,P51116,Q16629,Q96MU7,Q13243,Q9BWF3,P38159,Q9H0G5,Q5BKZ1,Q9NYV4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
249,272,762,532,20,278,682,519,671,411,409,288,287,290,568,427,184,566,693,199,194,68,200,321,320,697,698,214,470,213,234,610,229,367,114,734,515,120,653,251,786
|
1385,762,2165,519,1486,940,1239,1649,2997,1953,1345,287,200,866,767,1288,2784,2636,320,985,288,120,1186,1445,290,229,427,194,1664,2372,566,278,2327,409,1089,249,20,2513,1905,411,693,321,671,2126,568,951,1724,184,734,807,610,213,68,1793,1911,214,2132,697,698,367,880,2738,251,470,2187,1411,532,1799,2893,1567,114,1007,2251,1373,1215,515,653,1268,682,786,234,1019,2040,272,199,2205
|
0.024241586061113263,0.4302785616599747,-0.4019505979654591,0.6817554825782532,-0.03534902518693648,0.28742367409721314,0.11286018680823275,-0.1255210940747614,-1.432729732702481,-0.27797018357638537,0.05388250728134245,1.0595215210565851,1.3201682686463994,0.3448443594111074,0.4302785616599747,0.08342173825673257,-0.9173924403878517,-0.752788135498461,1.0065013303888994,0.25857156840411794,1.0595215210565851,1.722759492295663,0.14219874771718682,-0.005501946528574578,1.0595215210565851,1.2167829983083687,0.8184785830912821,1.345837421114375,-0.1255210940747614,-0.527804491720768,0.6264802495143728,1.0859177757996075,-0.49616131058878993,0.8455773188024565,0.2005797220728047,1.1646579241278294,3.7265538961328755,-0.6234698757692442,-0.2472593630138681,0.8455773188024565,0.4867792187177262,1.0065013303888994,0.5148951741567193,-0.37078271612329394,0.6264802495143728,0.28742367409721314,-0.15579198537738093,1.3714367183211587,0.4585739300606462,0.40189235684510055,0.5708620218746475,1.2686183881470232,2.3432469391311894,-0.18617130985484287,-0.2472593630138681,1.2686183881470232,-0.37078271612329394,0.4867792187177262,0.4867792187177262,0.9263931746254328,0.3448443594111074,-0.851146720270504,1.1646579241278294,0.7640371665537453,-0.4019505979654591,0.024241586061113263,0.6817554825782532,-0.18617130985484287,-1.119493098438248,-0.06530059846579093,1.820817302664816,0.25857156840411794,-0.4332355494784209,0.05388250728134245,0.14219874771718682,0.7092661942106616,0.5429225329450419,0.11286018680823275,0.5148951741567193,0.4302785616599747,1.2167829983083687,0.25857156840411794,-0.3087936217536729,1.112238890931671,1.345837421114375,-0.4019505979654591
| 3,120
|
Abnormal peripheral nervous system physiology
| 7
| 48
| 2.171311
| 0.029908
|
Q99720,Q9NQZ5,O95831,Q9GZY8,Q9NR77,O95721,P07196
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,107,13,207,15,54,27
|
2800,1427,1815,2208,937,226,601,54,13,662,628,27,1834,2007,463,2700,2115,606,2823,2174,2061,2546,1902,989,2508,3054,2765,2706,2017,1727,2237,638,1365,1513,1973,1412,417,2982,35,207,107,15,785,2721,1936,1170,900,460
|
-0.9507216839667448,-0.005501946528574578,-0.21666008975636944,-0.4332355494784209,0.28742367409721314,1.2167829983083687,0.5708620218746475,2.6170767103521797,4.470818556597859,0.5148951741567193,0.5429225329450419,3.271312628477843,-0.21666008975636944,-0.3087936217536729,0.7640371665537453,-0.8182272955248096,-0.37078271612329394,0.5708620218746475,-0.9841905255516471,-0.4019505979654591,-0.3397307645692643,-0.655607801353578,-0.2472593630138681,0.25857156840411794,-0.6234698757692442,-1.8337922669505038,-0.8842012814793642,-0.8182272955248096,-0.3087936217536729,-0.15579198537738093,-0.4332355494784209,0.5429225329450419,0.05388250728134245,-0.03534902518693648,-0.27797018357638537,0.024241586061113263,0.8455773188024565,-1.3620225182786942,3.014532465180862,1.2944287599319277,1.8937152051140331,4.356553869657722,0.4302785616599747,-0.8182272955248096,-0.2472593630138681,0.1714383029827371,0.3448443594111074,0.7912987450759194
| 3,120
|
Abnormality of salivation
| 18
| 47
| 2.167647
| 0.030186
|
Q15165,P15586,P51812,Q14739,P35637,Q92804,Q9UQN3,P35670,Q8N0X7,Q9NR77,Q13501,P43243,Q9UHD9,P42356,Q03252,Q99700,P55795,Q9H5V9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
64,497,634,611,288,136,175,544,369,15,268,606,573,365,335,620,566,357
|
1426,2209,1483,1703,796,3044,1489,1239,2318,497,1495,1496,288,544,365,606,1662,2424,1244,2287,634,2425,2508,566,2765,635,335,1090,1963,268,838,611,64,876,369,2084,136,2249,2982,1469,620,1166,2834,357,15,573,175
|
-0.005501946528574578,-0.4332355494784209,-0.03534902518693648,-0.15579198537738093,0.40189235684510055,-1.7592679631428478,-0.03534902518693648,0.11286018680823275,-0.49616131058878993,0.7092661942106616,-0.03534902518693648,-0.03534902518693648,1.0595215210565851,0.6541603945159422,0.9263931746254328,0.5708620218746475,-0.1255210940747614,-0.5595694864386637,0.11286018680823275,-0.4646387282720388,0.5429225329450419,-0.5595694864386637,-0.6234698757692442,0.6264802495143728,-0.8842012814793642,0.5429225329450419,0.9798762459794423,0.2005797220728047,-0.27797018357638537,1.112238890931671,0.37341454860880774,0.5708620218746475,2.435351140278348,0.3448443594111074,0.9263931746254328,-0.3397307645692643,1.6236938729897266,-0.4332355494784209,-1.3620225182786942,-0.005501946528574578,0.5708620218746475,0.1714383029827371,-0.9841905255516471,0.9531737247539802,4.356553869657722,0.6264802495143728,1.4224277222525785
| 3,120
|
Corneal opacity
| 14
| 55
| 2.163792
| 0.03048
|
O75845,P10619,P08236,O75844,P04066,Q15056,Q9Y6K9,P51648,Q9UBM7,O43505,P35670,Q13510,Q16625,O96028
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
2,496,495,98,378,480,597,41,373,43,544,60,241,274
|
1426,1176,43,2268,2310,2801,1129,1764,1430,903,98,2,2535,1484,274,662,1769,378,1706,495,2579,496,799,2007,905,2420,544,1400,41,871,2640,2064,1449,914,1961,2016,2433,60,1909,480,1199,1853,241,881,1678,1200,2948,972,621,894,373,2155,1381,1760,597
|
-0.005501946528574578,0.14219874771718682,2.7290289921712847,-0.4646387282720388,-0.49616131058878993,-0.9507216839667448,0.1714383029827371,-0.18617130985484287,-0.005501946528574578,0.3161810009783176,1.9420124373826877,6.275849522245003,-0.655607801353578,-0.03534902518693648,1.0859177757996075,0.5148951741567193,-0.18617130985484287,0.8995339961478345,-0.15579198537738093,0.7092661942106616,-0.6878726034160045,0.7092661942106616,0.40189235684510055,-0.3087936217536729,0.3161810009783176,-0.5595694864386637,0.6541603945159422,0.024241586061113263,2.8617795288788566,0.3448443594111074,-0.752788135498461,-0.3397307645692643,-0.005501946528574578,0.3161810009783176,-0.27797018357638537,-0.3087936217536729,-0.5595694864386637,2.526621237286272,-0.2472593630138681,0.7366932011575824,0.14219874771718682,-0.21666008975636944,1.1907569365536894,0.3448443594111074,-0.1255210940747614,0.14219874771718682,-1.2571576219277842,0.28742367409721314,0.5708620218746475,0.3448443594111074,0.9263931746254328,-0.37078271612329394,0.05388250728134245,-0.15579198537738093,0.5987143581404145
| 3,120
|
Aplasia hypoplasia involving bones of the feet
| 16
| 63
| 2.119507
| 0.034048
|
Q08J23,Q9UHX1,Q7LGA3,Q9UBM7,Q7RTS9,Q13510,Q69YQ0,Q9NX62,Q5JRA6,Q8N0X7,Q96S52,O75648,Q9H9E3,P13073,P00813,O96028
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
231,234,9,373,45,60,77,359,397,369,216,220,392,26,275,274
|
2838,2102,2103,1641,1823,1764,220,1484,2605,274,275,662,1889,26,1345,1346,2461,2367,2584,2325,1244,2425,2233,231,412,2433,60,1791,582,1852,1509,697,1853,881,397,77,3057,9,45,1201,2830,369,678,1466,2249,1160,748,572,216,1469,706,652,1015,392,2628,359,373,234,1381,977,2569,2570,1812
|
-1.0178005054933905,-0.37078271612329394,-0.37078271612329394,-0.1255210940747614,-0.21666008975636944,-0.18617130985484287,1.2427366405346731,-0.03534902518693648,-0.7202656010050781,1.0859177757996075,1.0859177757996075,0.5148951741567193,-0.2472593630138681,3.292431395300117,0.05388250728134245,0.05388250728134245,-0.5914575294331794,-0.527804491720768,-0.6878726034160045,-0.49616131058878993,0.11286018680823275,-0.5595694864386637,-0.4332355494784209,1.2167829983083687,0.8455773188024565,-0.5595694864386637,2.526621237286272,-0.18617130985484287,0.5987143581404145,-0.21666008975636944,-0.03534902518693648,0.4867792187177262,-0.21666008975636944,0.3448443594111074,0.8725955823893464,2.1092023745855184,-1.8337922669505038,4.658739680122686,2.7290289921712847,0.14219874771718682,-0.9841905255516471,0.9263931746254328,0.5148951741567193,-0.005501946528574578,-0.4332355494784209,0.1714383029827371,0.4585739300606462,0.6264802495143728,1.2686183881470232,-0.005501946528574578,0.4867792187177262,0.5429225329450419,0.25857156840411794,0.8995339961478345,-0.7202656010050781,0.9531737247539802,0.9263931746254328,1.2167829983083687,0.05388250728134245,0.28742367409721314,-0.655607801353578,-0.655607801353578,-0.18617130985484287
| 3,120
|
Impaired proprioception
| 17
| 38
| 2.115234
| 0.03441
|
Q13217,Q9Y6X9,O14773,O43819,O75298,Q8IV08,O95140,Q8N0X7,Q9NR77,Q96RR1,P41440,Q9H6K4,Q99700,P20700,P07196,P00846,P54802
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
161,460,157,131,346,531,601,369,15,617,48,117,620,463,27,30,500
|
2265,157,1426,1534,131,346,1393,601,30,2314,27,2276,1285,1834,463,2056,2115,48,989,500,2064,2508,2706,2015,161,638,1258,531,369,1972,2482,2982,617,620,117,15,1991,460
|
-0.4646387282720388,1.4731451750207736,-0.005501946528574578,-0.06530059846579093,1.6485562465385502,0.9531737247539802,0.024241586061113263,0.5708620218746475,3.250151677977301,-0.49616131058878993,3.271312628477843,-0.4646387282720388,0.08342173825673257,-0.21666008975636944,0.7640371665537453,-0.3397307645692643,-0.37078271612329394,2.6843950264914866,0.25857156840411794,0.7092661942106616,-0.3397307645692643,-0.6234698757692442,-0.8182272955248096,-0.3087936217536729,1.4731451750207736,0.5429225329450419,0.11286018680823275,0.6817554825782532,0.9263931746254328,-0.27797018357638537,-0.5914575294331794,-1.3620225182786942,0.5708620218746475,0.5708620218746475,1.7963958694618998,4.356553869657722,-0.27797018357638537,0.7912987450759194
| 3,120
|
Organelle fusion
| 14
| 52
| 2.112668
| 0.034629
|
Q96E52,O60313,Q9UQN3,Q9Y4W6,Q15075,P31751,Q9GZY8,Q9H6R6,O15400,Q8N2A8,O60499,O95721,O95249,Q9Y3E7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
100,226,175,201,292,167,207,178,202,339,181,54,211,459
|
1997,1232,202,721,226,1821,181,1078,2106,601,211,862,54,863,603,1238,1082,2411,167,2546,2872,2176,2473,1452,1355,3021,292,1201,2135,701,339,1973,100,1802,2029,1218,207,2146,458,178,593,1068,855,2037,1694,1271,2529,2450,175,459,201,1228
|
-0.3087936217536729,0.11286018680823275,1.2944287599319277,0.4585739300606462,1.2167829983083687,-0.21666008975636944,1.3714367183211587,0.2005797220728047,-0.37078271612329394,0.5708620218746475,1.2686183881470232,0.3448443594111074,2.6170767103521797,0.3448443594111074,0.5708620218746475,0.11286018680823275,0.2005797220728047,-0.5595694864386637,1.4224277222525785,-0.655607801353578,-1.0854501809743031,-0.4019505979654591,-0.5914575294331794,-0.005501946528574578,0.05388250728134245,-1.5400253415561875,1.0595215210565851,0.14219874771718682,-0.37078271612329394,0.4867792187177262,0.9798762459794423,-0.27797018357638537,1.9420124373826877,-0.18617130985484287,-0.3087936217536729,0.14219874771718682,1.2944287599319277,-0.37078271612329394,0.7912987450759194,1.3969666555059603,0.5987143581404145,0.22962386216876518,0.37341454860880774,-0.3087936217536729,-0.1255210940747614,0.11286018680823275,-0.6234698757692442,-0.5595694864386637,1.4224277222525785,0.7912987450759194,1.3201682686463994,0.14219874771718682
| 3,120
|
Inorganic molecular entity transmembrane transporter activity
| 27
| 76
| 2.111168
| 0.034758
|
P20674,Q9UM00,Q9UBX3,P13073,Q8TDW0,Q9UDW1,Q93034,P00846,Q9Y487,Q9Y277,P21796,Q93050,P36543,O14548,O75964,P00403,Q8N4V1,P16615,P24539,Q7KZN9,Q6N075,P20020,P06576,Q6P4Q7,O75947,Q13423,Q9HD20
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
379,538,420,26,416,29,555,30,166,53,304,62,192,189,190,441,340,333,82,384,97,349,477,483,364,118,258
|
2359,189,2208,364,190,1484,441,30,1705,663,2576,477,797,1082,1543,939,1707,1708,2667,2110,26,333,349,379,1346,667,304,906,82,1589,2700,544,802,192,1899,908,2788,1597,2505,2425,2326,1294,2645,2889,1192,2648,2927,2553,609,118,2845,612,97,483,384,340,1100,745,416,555,62,2658,1569,1376,2094,1117,258,929,420,29,1695,538,53,166,2987,1636
|
-0.527804491720768,1.345837421114375,-0.4332355494784209,0.9263931746254328,1.345837421114375,-0.03534902518693648,0.7912987450759194,3.250151677977301,-0.15579198537738093,0.5148951741567193,-0.6878726034160045,0.7366932011575824,0.40189235684510055,0.2005797220728047,-0.06530059846579093,0.28742367409721314,-0.15579198537738093,-0.15579198537738093,-0.7854415711286908,-0.37078271612329394,3.292431395300117,0.9798762459794423,0.9531737247539802,0.8995339961478345,0.05388250728134245,0.5148951741567193,1.0330495628348084,0.3161810009783176,2.061723178700731,-0.09535762905488879,-0.8182272955248096,0.6541603945159422,0.40189235684510055,1.345837421114375,-0.2472593630138681,0.3161810009783176,-0.9173924403878517,-0.09535762905488879,-0.6234698757692442,-0.5595694864386637,-0.49616131058878993,0.08342173825673257,-0.752788135498461,-1.119493098438248,0.14219874771718682,-0.752788135498461,-1.1880233702760612,-0.655607801353578,0.5708620218746475,1.7719126974504582,-1.0178005054933905,0.5708620218746475,1.966071809474578,0.7366932011575824,0.8995339961478345,0.9798762459794423,0.2005797220728047,0.4585739300606462,0.8455773188024565,0.6541603945159422,2.4582460880874186,-0.752788135498461,-0.06530059846579093,0.05388250728134245,-0.3397307645692643,0.2005797220728047,1.1646579241278294,0.3161810009783176,0.8455773188024565,3.271312628477843,-0.1255210940747614,0.6817554825782532,2.6620048510442116,1.44782040257826,-1.3620225182786942,-0.09535762905488879
| 3,120
|
Protein targeting to mitochondrion
| 13
| 48
| 2.084498
| 0.037115
|
Q9H300,Q10713,O60830,P55786,O14737,O95831,Q9NS69,Q9GZY8,Q8N4H5,P51572,Q5JRX3,O14925,Q9P0J0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
458,67,319,12,266,13,402,207,50,426,467,210,198
|
2265,2724,266,210,2408,1235,319,1079,1947,1883,601,1394,13,1768,1951,2276,1653,2611,2114,870,2704,426,12,1959,67,877,1361,641,482,467,1201,50,1973,706,2658,2600,207,458,1118,402,198,2662,1477,2097,596,1071,3064,3087
|
-0.4646387282720388,-0.851146720270504,1.112238890931671,1.2686183881470232,-0.5595694864386637,0.11286018680823275,1.0065013303888994,0.2005797220728047,-0.27797018357638537,-0.2472593630138681,0.5708620218746475,0.024241586061113263,4.470818556597859,-0.18617130985484287,-0.27797018357638537,-0.4646387282720388,-0.1255210940747614,-0.7202656010050781,-0.37078271612329394,0.3448443594111074,-0.8182272955248096,0.8184785830912821,4.565166618578091,-0.27797018357638537,2.3432469391311894,0.3448443594111074,0.05388250728134245,0.5429225329450419,0.7366932011575824,0.7640371665537453,0.14219874771718682,2.6620048510442116,-0.27797018357638537,0.4867792187177262,-0.752788135498461,-0.6878726034160045,1.2944287599319277,0.7912987450759194,0.2005797220728047,0.8725955823893464,1.345837421114375,-0.752788135498461,-0.005501946528574578,-0.3397307645692643,0.5987143581404145,0.22962386216876518,-1.9090699908473854,-2.337517409740309
| 3,120
|
EF-hand domain pair [IPR011992]
| 19
| 48
| 2.084024
| 0.037158
|
P80303,P43304,Q02818,O43852,Q8NF37,O75746,Q9UPN3,Q14257,P17655,Q13813,Q15293,P46939,Q96C19,Q8N163,Q99584,Q9UJS0,O75340,Q96AY3,Q9H4M9
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
8,632,24,151,552,661,438,42,666,428,323,579,749,614,490,624,363,648,654
|
1390,151,363,661,1484,1771,1083,2868,1587,666,1286,2821,2870,1900,1498,632,579,2825,3024,8,24,1961,428,42,2795,323,958,1678,1045,2297,885,614,552,648,749,1208,490,1057,1213,1214,754,654,1065,2036,1990,895,624,438
|
0.024241586061113263,1.4984025127237648,0.9263931746254328,0.5148951741567193,-0.03534902518693648,-0.18617130985484287,0.2005797220728047,-1.0854501809743031,-0.09535762905488879,0.5148951741567193,0.08342173825673257,-0.9841905255516471,-1.0854501809743031,-0.2472593630138681,-0.03534902518693648,0.5429225329450419,0.5987143581404145,-0.9841905255516471,-1.5761279420843397,4.677362749009189,3.3764889848748334,-0.27797018357638537,0.8184785830912821,2.817719086971732,-0.9173924403878517,1.0065013303888994,0.28742367409721314,-0.1255210940747614,0.22962386216876518,-0.4646387282720388,0.3448443594111074,0.5708620218746475,0.6541603945159422,0.5429225329450419,0.4585739300606462,0.14219874771718682,0.7366932011575824,0.22962386216876518,0.14219874771718682,0.14219874771718682,0.4585739300606462,0.5429225329450419,0.22962386216876518,-0.3087936217536729,-0.27797018357638537,0.3448443594111074,0.5708620218746475,0.8184785830912821
| 3,120
|
Proton transmembrane transporter activity
| 14
| 35
| 2.047217
| 0.040637
|
P36543,Q9Y487,P20674,O14548,O75964,P00403,O75947,Q13423,P24539,Q93050,P13073,Q9UDW1,P00846,Q7KZN9
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,166,379,189,190,441,364,118,82,62,26,29,30,384
|
189,364,190,1484,441,30,2576,477,1707,2667,2110,26,379,1346,667,82,1589,2700,802,192,1899,2788,1597,2505,2326,1294,2645,2648,118,384,62,1117,29,1695,166
|
1.345837421114375,0.9263931746254328,1.345837421114375,-0.03534902518693648,0.7912987450759194,3.250151677977301,-0.6878726034160045,0.7366932011575824,-0.15579198537738093,-0.7854415711286908,-0.37078271612329394,3.292431395300117,0.8995339961478345,0.05388250728134245,0.5148951741567193,2.061723178700731,-0.09535762905488879,-0.8182272955248096,0.40189235684510055,1.345837421114375,-0.2472593630138681,-0.9173924403878517,-0.09535762905488879,-0.6234698757692442,-0.49616131058878993,0.08342173825673257,-0.752788135498461,-0.752788135498461,1.7719126974504582,0.8995339961478345,2.4582460880874186,0.2005797220728047,3.271312628477843,-0.1255210940747614,1.44782040257826
| 3,120
|
Regulation of mrna processing
| 38
| 85
| 2.023165
| 0.043056
|
P98175,Q9Y2W1,P09012,Q69YN4,P26368,P98179,Q8N684,P61978,O75494,Q08170,Q96ST2,Q07021,P62995,P19338,P51114,Q13242,Q07666,Q9Y580,P52756,Q14011,P22626,Q15427,Q15637,Q6PD62,Q15007,Q13595,O75150,Q6PJT7,Q9UHX1,Q13573,P51116,P50750,Q9NWH9,Q16629,Q96MU7,Q9BWF3,P38159,Q9H0G5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
249,272,765,528,767,20,677,278,519,671,297,411,409,287,290,184,693,199,194,68,200,697,698,742,214,213,461,484,234,610,229,729,112,367,114,515,120,653
|
758,1385,1580,827,461,519,1486,940,765,1239,1649,2997,1953,1345,2728,287,200,767,1288,2784,2636,120,1445,729,1957,290,229,194,1664,278,409,1089,249,20,2513,411,693,671,1722,2126,1724,184,807,610,213,68,1454,1793,214,2132,2020,697,698,367,840,880,2738,998,528,1038,742,484,1040,2187,1411,677,1001,1799,2893,1567,114,1007,2251,297,1373,1215,515,653,1870,112,234,2040,272,199,2205
|
0.4302785616599747,0.024241586061113263,-0.09535762905488879,0.37341454860880774,0.7640371665537453,0.6817554825782532,-0.03534902518693648,0.28742367409721314,0.4302785616599747,0.11286018680823275,-0.1255210940747614,-1.432729732702481,-0.27797018357638537,0.05388250728134245,-0.851146720270504,1.0595215210565851,1.3201682686463994,0.4302785616599747,0.08342173825673257,-0.9173924403878517,-0.752788135498461,1.722759492295663,-0.005501946528574578,0.4585739300606462,-0.27797018357638537,1.0595215210565851,1.2167829983083687,1.345837421114375,-0.1255210940747614,1.0859177757996075,0.8455773188024565,0.2005797220728047,1.1646579241278294,3.7265538961328755,-0.6234698757692442,0.8455773188024565,0.4867792187177262,0.5148951741567193,-0.15579198537738093,-0.37078271612329394,-0.15579198537738093,1.3714367183211587,0.40189235684510055,0.5708620218746475,1.2686183881470232,2.3432469391311894,-0.005501946528574578,-0.18617130985484287,1.2686183881470232,-0.37078271612329394,-0.3087936217536729,0.4867792187177262,0.4867792187177262,0.9263931746254328,0.37341454860880774,0.3448443594111074,-0.851146720270504,0.25857156840411794,0.6817554825782532,0.22962386216876518,0.4585739300606462,0.7366932011575824,0.22962386216876518,-0.4019505979654591,0.024241586061113263,0.5148951741567193,0.25857156840411794,-0.18617130985484287,-1.119493098438248,-0.06530059846579093,1.820817302664816,0.25857156840411794,-0.4332355494784209,1.0595215210565851,0.05388250728134245,0.14219874771718682,0.7092661942106616,0.5429225329450419,-0.21666008975636944,1.8451774027700232,1.2167829983083687,-0.3087936217536729,1.112238890931671,1.345837421114375,-0.4019505979654591
| 3,120
|
Intermediate filament protein, conserved site [IPR018039]
| 7
| 8
| 2.002387
| 0.045243
|
P08670,Q16352,P02545,P07197,Q03252,P20700,P07196
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
191,293,662,442,335,463,27
|
662,27,442,191,463,668,335,293
|
0.5148951741567193,3.271312628477843,0.7912987450759194,1.345837421114375,0.7640371665537453,0.5148951741567193,0.9798762459794423,1.0595215210565851
| 3,120
|
Intermediate filament, rod domain [IPR039008]
| 7
| 8
| 2.002387
| 0.045243
|
P08670,Q16352,P02545,P07197,Q03252,P20700,P07196
|
Sequence
|
InterPro Domain
|
interpro_domain
|
191,293,662,442,335,463,27
|
662,27,442,191,463,668,335,293
|
0.5148951741567193,3.271312628477843,0.7912987450759194,1.345837421114375,0.7640371665537453,0.5148951741567193,0.9798762459794423,1.0595215210565851
| 3,120
|
Abnormality of the calf
| 11
| 58
| 1.99856
| 0.045656
|
O75718,Q7LGA3,Q13126,Q7RTS9,O95831,Q9NR77,Q32P28,Q96L58,Q8N0X7,Q9NWH9,Q9NX62
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
347,9,240,45,13,15,144,370,369,112,359
|
2161,2310,2165,1764,577,347,1180,13,2050,2213,495,2867,799,1651,1831,2461,1085,2584,2054,2420,2369,1497,2422,1349,1449,635,914,2431,609,1196,240,1558,480,697,1854,144,9,45,2385,369,1466,2137,401,370,1006,2918,2093,2798,15,1809,2852,112,359,2155,1381,2489,1760,2205
|
-0.4019505979654591,-0.49616131058878993,-0.4019505979654591,-0.18617130985484287,0.5987143581404145,0.9531737247539802,0.14219874771718682,4.470818556597859,-0.3397307645692643,-0.4332355494784209,0.7092661942106616,-1.0854501809743031,0.40189235684510055,-0.1255210940747614,-0.21666008975636944,-0.5914575294331794,0.2005797220728047,-0.6878726034160045,-0.3397307645692643,-0.5595694864386637,-0.527804491720768,-0.03534902518693648,-0.5595694864386637,0.05388250728134245,-0.005501946528574578,0.5429225329450419,0.3161810009783176,-0.5595694864386637,0.5708620218746475,0.14219874771718682,1.1907569365536894,-0.06530059846579093,0.7366932011575824,0.4867792187177262,-0.21666008975636944,1.5487167500155263,4.658739680122686,2.7290289921712847,-0.527804491720768,0.9263931746254328,-0.005501946528574578,-0.37078271612329394,0.8725955823893464,0.9263931746254328,0.25857156840411794,-1.1536835995610857,-0.3397307645692643,-0.9173924403878517,4.356553869657722,-0.18617130985484287,-1.0178005054933905,1.8451774027700232,0.9531737247539802,-0.37078271612329394,0.05388250728134245,-0.5914575294331794,-0.15579198537738093,-0.4019505979654591
| 3,120
|
mRNA splicing factor
| 37
| 58
| 1.977192
| 0.04802
|
Q15233,O43395,Q15428,Q92804,P09012,Q12874,P98179,O75494,Q08170,Q01844,P62995,P35637,P19338,P08579,O43719,P23246,Q13242,Q8WXF1,Q13247,Q07666,P08621,Q14011,Q07955,P33240,Q15637,Q13595,Q96PU8,P62314,Q15020,Q9BZJ0,Q15459,Q16629,Q13243,Q9BWF3,P09661,Q96PK6,P38159
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
876,375,774,136,765,769,20,519,671,913,409,288,287,540,423,425,184,453,807,693,940,68,321,446,698,213,1007,837,839,1012,481,367,734,515,864,650,120
|
1578,375,423,1580,519,1582,2757,2271,540,940,765,864,287,425,446,288,120,2793,2674,837,3072,409,1089,20,913,693,321,671,2126,1724,769,184,734,807,213,68,839,876,2132,2594,774,481,698,367,2335,1798,1000,2187,1307,453,136,650,1007,515,1012,1267,2263,2899
|
-0.09535762905488879,0.8995339961478345,0.8184785830912821,-0.09535762905488879,0.6817554825782532,-0.09535762905488879,-0.8842012814793642,-0.4646387282720388,0.6541603945159422,0.28742367409721314,0.4302785616599747,0.3448443594111074,1.0595215210565851,0.8184785830912821,0.7912987450759194,1.0595215210565851,1.722759492295663,-0.9173924403878517,-0.7854415711286908,0.37341454860880774,-1.9851213967446948,0.8455773188024565,0.2005797220728047,3.7265538961328755,0.3161810009783176,0.4867792187177262,1.0065013303888994,0.5148951741567193,-0.37078271612329394,-0.15579198537738093,0.4302785616599747,1.3714367183211587,0.4585739300606462,0.40189235684510055,1.2686183881470232,2.3432469391311894,0.37341454860880774,0.3448443594111074,-0.37078271612329394,-0.6878726034160045,0.4302785616599747,0.7366932011575824,0.4867792187177262,0.9263931746254328,-0.49616131058878993,-0.18617130985484287,0.25857156840411794,-0.4019505979654591,0.08342173825673257,0.7912987450759194,1.6236938729897266,0.5429225329450419,0.25857156840411794,0.7092661942106616,0.25857156840411794,0.11286018680823275,-0.4332355494784209,-1.119493098438248
| 3,120
|
Difficulty walking
| 20
| 81
| 3.378382
| 0.000729
|
Q9NR77,Q99720,P04792,P00846,Q13510,P35670,Q96HY7,Q15907,P51530,P35637,O14773,Q96F07,O75298,Q8TD16,Q9ULV3,Q15067,Q13057,P02792,O75792,O75340
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
131,16,17,21,25,154,415,29,409,289,54,193,64,201,204,341,338,347,361,255
|
3093,1121,2870,2343,54,1592,2294,64,255,1668,361,787,2110,21,347,17,936,1924,2519,1797,2304,1866,1737,289,154,1423,1350,1292,1869,1545,2187,409,892,2447,2123,2398,2678,486,1299,1554,2259,1431,900,338,953,25,2199,2314,1690,1559,341,2406,29,2072,1309,2268,1443,735,2364,1566,201,1701,1319,2080,1769,193,415,710,16,2613,2013,824,2018,2462,131,1658,455,204,782,2164,558
|
-2.6532132109667135,0.16725085745394358,-1.0481825276350252,-0.4830896335468625,2.5201273376889914,-0.08614306228071349,-0.4491857450646144,2.473520663548231,1.1046946053418571,-0.1184255560889291,0.8806784880076532,0.3822373090241425,-0.34839980353590916,3.589666359430854,0.9090305091884525,3.73234337597373,0.2908401877882903,-0.2489679916884096,-0.6202939338075241,-0.18341135031770928,-0.4491857450646144,-0.21611757016080707,-0.15084783616861905,1.021430170623449,1.4821804503241371,0.00987983300086082,0.041617201213464,0.07322168259168828,-0.21611757016080707,-0.053998930248529343,-0.38184249878506293,0.7950034180823421,0.32142726272319516,-0.5513705034966245,-0.34839980353590916,-0.5171506389207149,-0.7601272692699352,0.6792917290732912,0.07322168259168828,-0.053998930248529343,-0.41543726115414226,0.00987983300086082,0.32142726272319516,0.9372808306752206,0.2908401877882903,3.4863342700949986,-0.38184249878506293,-0.4491857450646144,-0.1184255560889291,-0.053998930248529343,0.9372808306752206,-0.5171506389207149,3.3396104265019546,-0.31510754893352083,0.07322168259168828,-0.41543726115414226,0.00987983300086082,0.44256943928456016,-0.4830896335468625,-0.053998930248529343,1.2956579381594955,-0.1184255560889291,0.07322168259168828,-0.31510754893352083,-0.15084783616861905,1.3225701226794089,0.7950034180823421,0.4725590568983185,3.8727794768615476,-0.6898744907977593,-0.2819641358117063,0.3822373090241425,-0.2819641358117063,-0.5513705034966245,1.6645000841134392,-0.08614306228071349,0.737361844928647,1.2956579381594955,0.41246255537526794,-0.34839980353590916,0.620785416766542
| 3,120
|
Phospholipid binding
| 16
| 83
| 3.181164
| 0.001467
|
Q9UM22,P50897,Q9Y3E7,Q8WTV0,Q8NCC3,Q9NZD2,Q9BWH2,Q15075,P53367,Q9Y4G8,P45880,P04083,Q9H4A6,O14773,P21796,Q14108
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
132,66,166,40,9,144,143,264,48,18,114,173,210,54,55,57
|
1079,2588,2694,54,1593,2712,1526,2436,481,654,273,1025,1853,173,1344,3001,2347,1131,937,1033,2873,2956,1037,1289,55,2040,940,2698,694,114,658,1245,1681,66,1142,48,1300,1622,759,666,903,1689,57,571,1257,763,264,1435,2006,1564,2205,3110,9,3013,40,2207,2458,862,603,1267,1772,1212,143,1067,1014,1387,210,144,1658,2507,1585,874,2286,132,1225,1718,405,166,1077,18,2887,2587,834
|
0.19833674271283955,-0.6898744907977593,-0.7955106096971893,2.5201273376889914,-0.08614306228071349,-0.8310679190732748,-0.053998930248529343,-0.5513705034966245,0.6792917290732912,0.5024324884152008,1.0492822102543629,0.2292961177027244,-0.21611757016080707,1.3761255827105783,0.041617201213464,-1.5033848001965395,-0.4830896335468625,0.16725085745394358,0.2908401877882903,0.2292961177027244,-1.0481825276350252,-1.2721109771809347,0.2292961177027244,0.07322168259168828,2.5201273376889914,-0.31510754893352083,0.2908401877882903,-0.7955106096971893,0.4725590568983185,1.8428352501005447,0.5024324884152008,0.10469459248892066,-0.1184255560889291,2.450120794834704,0.16725085745394358,2.704040211629657,0.07322168259168828,-0.08614306228071349,0.41246255537526794,0.5024324884152008,0.32142726272319516,-0.1184255560889291,2.5201273376889914,0.5913662357262023,0.10469459248892066,0.41246255537526794,1.0770367526339741,0.00987983300086082,-0.2819641358117063,-0.053998930248529343,-0.38184249878506293,-3.544370843342836,4.853248309205084,-1.542685596784021,2.9285094233950213,-0.38184249878506293,-0.5513705034966245,0.3518925878136761,0.5618350360996074,0.10469459248892066,-0.15084783616861905,0.13603722581215738,1.5868633066597473,0.2292961177027244,0.2601301997513227,0.041617201213464,1.2686551612087744,1.5868633066597473,-0.08614306228071349,-0.5857510002982927,-0.053998930248529343,0.3518925878136761,-0.41543726115414226,1.6645000841134392,0.13603722581215738,-0.1184255560889291,0.8236658353112523,1.4293271889869001,0.2292961177027244,3.71210011534424,-1.0481825276350252,-0.6550011407321256,0.3822373090241425
| 3,120
|
Ion transmembrane transporter activity
| 26
| 105
| 3.109633
| 0.001873
|
Q13423,P00846,Q9UDW1,O43772,P13073,P35670,P36543,Q9BQT8,P41440,Q9Y277,Q8N4V1,P21796,O14548,Q9Y487,P20674,P24539,O75947,Q8TDW0,Q70HW3,Q93050,Q14847,P30825,Q9H2D1,Q6N075,O75964,P45880
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
147,21,24,27,28,154,159,39,44,49,309,55,62,333,190,76,318,209,82,220,352,91,96,95,113,114
|
2100,62,583,2294,27,1082,751,318,113,1179,2232,619,21,1858,1342,2299,534,1793,1344,2347,1092,2174,3061,2718,536,2894,2237,28,348,504,190,459,885,55,2593,76,1608,91,2634,154,693,159,1423,44,114,2898,943,2188,2447,1550,1001,2763,802,2789,2729,2195,2257,2764,2491,2128,147,2534,352,2449,1367,2267,95,1695,2408,1497,702,2268,82,400,309,703,1156,1262,209,2651,1158,220,1568,1707,39,1959,1573,2334,96,2906,2151,826,2462,522,1018,2803,647,24,1780,780,745,49,333,2925,2663
|
-0.34839980353590916,2.473520663548231,0.5618350360996074,-0.4491857450646144,3.423751167382198,0.19833674271283955,0.41246255537526794,0.9654303155685332,1.8428352501005447,0.13603722581215738,-0.41543726115414226,0.5321907984016734,3.589666359430854,-0.21611757016080707,0.041617201213464,-0.4491857450646144,0.620785416766542,-0.18341135031770928,0.041617201213464,-0.4830896335468625,0.19833674271283955,-0.38184249878506293,-2.032649954860639,-0.8310679190732748,0.620785416766542,-1.122043291912447,-0.41543726115414226,3.423751167382198,0.9090305091884525,0.6500935842589323,1.3225701226794089,0.708380828182735,0.32142726272319516,2.5201273376889914,-0.6898744907977593,2.2605480296054683,-0.08614306228071349,2.091083091944511,-0.7249158875646223,1.4821804503241371,0.4725590568983185,1.4557970237686562,0.00987983300086082,2.7945327251855265,1.8428352501005447,-1.122043291912447,0.2908401877882903,-0.38184249878506293,-0.5513705034966245,-0.053998930248529343,0.2601301997513227,-0.8668012449944402,0.3822373090241425,-0.9027126733824001,-0.8310679190732748,-0.38184249878506293,-0.41543726115414226,-0.8668012449944402,-0.5857510002982927,-0.34839980353590916,1.5608189168337658,-0.6202939338075241,0.9090305091884525,-0.5513705034966245,0.041617201213464,-0.41543726115414226,2.0665902618265855,-0.1184255560889291,-0.5171506389207149,-0.021991758289780373,0.4725590568983185,-0.41543726115414226,2.1883406422631806,0.8236658353112523,0.9934798154564681,0.4725590568983185,0.16725085745394358,0.10469459248892066,1.2686551612087744,-0.7249158875646223,0.16725085745394358,1.2415610633760816,-0.053998930248529343,-0.1184255560889291,2.97270991371045,-0.2489679916884096,-0.053998930248529343,-0.4491857450646144,2.0665902618265855,-1.122043291912447,-0.34839980353590916,0.3822373090241425,-0.5513705034966245,0.6500935842589323,0.2601301997513227,-0.9027126733824001,0.5321907984016734,3.5278117162155356,-0.15084783616861905,0.41246255537526794,0.44256943928456016,2.681266849929279,0.9654303155685332,-1.1592632785117458,-0.7249158875646223
| 3,120
|
Rnd2 gtpase cycle
| 6
| 18
| 2.976909
| 0.002912
|
Q07065,O00459,P38159,P51648,Q8TAA9,Q03001
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
37,137,138,43,174,381
|
137,1229,1341,138,43,381,37,1302,1625,1109,1636,174,1265,1163,2425,649,405,1661
|
1.6128245467816795,0.10469459248892066,0.041617201213464,1.6128245467816795,2.817007494245751,0.8522238923059385,3.01668582144507,0.07322168259168828,-0.08614306228071349,0.19833674271283955,-0.08614306228071349,1.3761255827105783,0.10469459248892066,0.16725085745394358,-0.5171506389207149,0.5321907984016734,0.8236658353112523,-0.08614306228071349
| 3,120
|
Cholesterol biosynthesis
| 8
| 18
| 2.964224
| 0.003034
|
P48449,Q16850,Q14534,P37268,O95749,P04035,Q9UBM7,Q15392
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
167,171,197,20,304,274,253,31
|
1731,304,274,794,20,167,1804,1619,2533,197,598,1628,31,2407,1944,171,356,253
|
-0.15084783616861905,0.9934798154564681,1.0492822102543629,0.3822373090241425,3.6306648569855366,1.4027702700675502,-0.18341135031770928,-0.08614306228071349,-0.6202939338075241,1.2956579381594955,0.5618350360996074,-0.08614306228071349,3.233289173865552,-0.5171506389207149,-0.2489679916884096,1.4027702700675502,0.9090305091884525,1.1322565654429038
| 3,120
|
Limb muscle weakness
| 17
| 85
| 2.864285
| 0.00418
|
O75298,P54098,Q13126,Q9NR77,P50402,P36551,Q9BQT8,O43819,Q15650,Q15067,Q99720,P04792,P00846,Q13510,P07196,P35670,Q86U42
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
64,379,93,131,349,133,39,229,308,341,16,17,21,25,59,154,383
|
1463,1592,785,2751,229,64,1978,787,21,1028,17,1858,936,59,1924,1606,2236,2894,1797,1098,1289,2783,1737,154,133,694,2246,1424,1869,1545,1872,349,2187,2599,2447,379,2676,1993,2398,2728,2678,1994,1554,2570,2311,900,93,953,25,2199,1152,1364,1690,598,2765,341,2406,1003,308,1197,1945,1110,2072,1443,2320,383,491,735,2839,2649,861,401,2080,2417,2798,2904,1956,710,16,39,1708,131,1782,717,558
|
-0.021991758289780373,-0.08614306228071349,0.3822373090241425,-0.8668012449944402,1.187095944623876,2.473520663548231,-0.2819641358117063,0.3822373090241425,3.589666359430854,0.2292961177027244,3.73234337597373,-0.21611757016080707,0.2908401877882903,2.4968560374821402,-0.2489679916884096,-0.08614306228071349,-0.41543726115414226,-1.122043291912447,-0.18341135031770928,0.19833674271283955,0.07322168259168828,-0.9027126733824001,-0.15084783616861905,1.4821804503241371,1.6387032656167018,0.4725590568983185,-0.41543726115414226,0.00987983300086082,-0.21611757016080707,-0.053998930248529343,-0.21611757016080707,0.9090305091884525,-0.38184249878506293,-0.6898744907977593,-0.5513705034966245,0.8522238923059385,-0.7601272692699352,-0.2819641358117063,-0.5171506389207149,-0.8310679190732748,-0.7601272692699352,-0.2819641358117063,-0.053998930248529343,-0.6550011407321256,-0.4491857450646144,0.32142726272319516,2.0665902618265855,0.2908401877882903,3.4863342700949986,-0.38184249878506293,0.16725085745394358,0.041617201213464,-0.1184255560889291,0.5618350360996074,-0.8668012449944402,0.9372808306752206,-0.5171506389207149,0.2601301997513227,0.9934798154564681,0.13603722581215738,-0.2489679916884096,0.19833674271283955,-0.31510754893352083,0.00987983300086082,-0.4491857450646144,0.8522238923059385,0.6792917290732912,0.44256943928456016,-0.9750783788289236,-0.7249158875646223,0.3518925878136761,0.8236658353112523,-0.31510754893352083,-0.5171506389207149,-0.9027126733824001,-1.122043291912447,-0.2489679916884096,0.4725590568983185,3.8727794768615476,2.97270991371045,-0.1184255560889291,1.6645000841134392,-0.15084783616861905,0.4725590568983185,0.620785416766542
| 3,120
|
Cytochrome complex
| 6
| 18
| 2.75121
| 0.005938
|
P14927,O14949,P14406,Q9UDW1,P13073,O14548
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
71,14,46,24,28,62
|
2101,62,14,619,2174,566,2718,28,46,71,1861,190,620,2634,2898,400,24,2339
|
-0.34839980353590916,2.473520663548231,4.376094826005348,0.5321907984016734,-0.38184249878506293,0.5913662357262023,-0.8310679190732748,3.423751167382198,2.749405899890943,2.3795299433115717,-0.21611757016080707,1.3225701226794089,0.5321907984016734,-0.7249158875646223,-1.122043291912447,0.8236658353112523,3.5278117162155356,-0.4491857450646144
| 3,120
|
Ectrodactyly
| 6
| 17
| 2.746472
| 0.006024
|
Q9NR77,P48449,Q99720,P04792,Q6DKJ4,P07196
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
131,167,16,17,115,59
|
1179,1473,17,59,167,1937,2402,2313,1110,398,115,2649,16,131,2466,253,558
|
0.13603722581215738,-0.021991758289780373,3.73234337597373,2.4968560374821402,1.4027702700675502,-0.2489679916884096,-0.5171506389207149,-0.4491857450646144,0.19833674271283955,0.8236658353112523,1.8428352501005447,-0.7249158875646223,3.8727794768615476,1.6645000841134392,-0.5513705034966245,1.1322565654429038,0.620785416766542
| 3,120
|
Amyotrophic lateral sclerosis
| 6
| 18
| 2.70647
| 0.0068
|
Q9UHD9,Q99720,P22626,Q9UQN3,Q92804,Q15165
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
140,16,276,212,251,30
|
1855,3001,1347,276,1737,289,1292,1142,2398,1688,953,1152,30,251,711,16,140,212
|
-0.21611757016080707,-1.5033848001965395,0.041617201213464,1.0492822102543629,-0.15084783616861905,1.021430170623449,0.07322168259168828,0.16725085745394358,-0.5171506389207149,-0.1184255560889291,0.2908401877882903,0.16725085745394358,3.3184489550204734,1.1322565654429038,0.4725590568983185,3.8727794768615476,1.6128245467816795,1.2686551612087744
| 3,120
|
Alcohol metabolic process
| 14
| 82
| 2.647513
| 0.008109
|
P00374,Q9UHB6,P48449,Q8WTV0,Q9NX62,P51648,Q16850,Q10713,Q14534,P37268,P48735,Q13510,Q9UBM7,Q15392
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,227,167,40,239,43,171,77,197,20,183,25,253,31
|
2220,560,785,2751,2435,2696,2032,1668,1731,1086,1978,2715,0,2670,274,1602,2671,1032,838,1476,794,2176,2386,2039,1735,2808,720,1613,2306,20,2183,1615,167,183,506,2598,1991,892,43,1746,1804,2189,2964,2252,3096,1189,1554,1619,949,77,852,25,2533,197,598,763,1628,31,2407,1944,2495,171,445,1155,1895,2365,2011,40,605,3044,2952,2548,451,712,1516,1389,239,418,253,227,1907,2340
|
-0.41543726115414226,0.5913662357262023,0.3822373090241425,-0.8668012449944402,-0.5513705034966245,-0.7955106096971893,-0.31510754893352083,-0.1184255560889291,-0.15084783616861905,0.19833674271283955,-0.2819641358117063,-0.8310679190732748,6.892927341166569,-0.7601272692699352,1.0492822102543629,-0.08614306228071349,-0.7601272692699352,0.2292961177027244,0.3518925878136761,-0.021991758289780373,0.3822373090241425,-0.38184249878506293,-0.5171506389207149,-0.31510754893352083,-0.15084783616861905,-0.938804329471579,0.44256943928456016,-0.08614306228071349,-0.4491857450646144,3.6306648569855366,-0.38184249878506293,-0.08614306228071349,1.4027702700675502,1.349392434084322,0.6500935842589323,-0.6898744907977593,-0.2819641358117063,0.32142726272319516,2.817007494245751,-0.15084783616861905,-0.18341135031770928,-0.38184249878506293,-1.3101312220661574,-0.41543726115414226,-2.6532132109667135,0.13603722581215738,-0.053998930248529343,-0.08614306228071349,0.2908401877882903,2.2605480296054683,0.3518925878136761,3.4863342700949986,-0.6202939338075241,1.2956579381594955,0.5618350360996074,0.41246255537526794,-0.08614306228071349,3.233289173865552,-0.5171506389207149,-0.2489679916884096,-0.5857510002982927,1.4027702700675502,0.737361844928647,0.16725085745394358,-0.21611757016080707,-0.4830896335468625,-0.2819641358117063,2.9285094233950213,0.5618350360996074,-1.8242247352808862,-1.2342946167634679,-0.6202939338075241,0.737361844928647,0.4725590568983185,-0.021991758289780373,0.041617201213464,1.187095944623876,0.7950034180823421,1.1322565654429038,1.2143749069155765,-0.21611757016080707,-0.4491857450646144
| 3,120
|
Motor neuron atrophy
| 8
| 24
| 2.55155
| 0.010724
|
P35637,Q9UHD9,Q92804,Q99720,Q9UQN3,Q13510,P22626,Q15165
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
289,140,251,16,212,25,276,30
|
1855,3001,1347,1930,276,1737,289,1292,1142,2398,1688,953,25,1152,30,1945,401,251,711,16,1268,2094,140,212
|
-0.21611757016080707,-1.5033848001965395,0.041617201213464,-0.2489679916884096,1.0492822102543629,-0.15084783616861905,1.021430170623449,0.07322168259168828,0.16725085745394358,-0.5171506389207149,-0.1184255560889291,0.2908401877882903,3.4863342700949986,0.16725085745394358,3.3184489550204734,-0.2489679916884096,0.8236658353112523,1.1322565654429038,0.4725590568983185,3.8727794768615476,0.10469459248892066,-0.31510754893352083,1.6128245467816795,1.2686551612087744
| 3,120
|
Negative regulation of cellular amide metabolic process
| 17
| 86
| 2.510333
| 0.012062
|
P00374,Q14011,O75298,Q9NQC3,Q13464,P52758,Q96PZ0,Q9BPZ3,P67809,Q969T7,Q10713,Q14444,P19338,Q9UIV1,Q00577,Q92600,O60506
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,65,64,262,327,134,74,269,110,13,77,368,230,404,397,283,301
|
1847,1464,749,1913,301,562,837,2344,64,1177,1127,1856,0,2630,790,1030,1182,1604,1859,656,230,1537,1415,1866,2828,2633,1737,996,2046,1739,2929,1935,2786,724,408,134,2489,1144,2930,3058,110,397,2258,1147,1879,1941,77,2129,1688,327,1492,65,570,368,905,957,2901,2537,1112,512,1499,3027,1700,283,2704,773,918,13,636,1505,74,269,518,2421,1321,2422,1516,1117,262,1904,2154,1838,404,1587,1912,682
|
-0.21611757016080707,-0.021991758289780373,0.41246255537526794,-0.2489679916884096,0.9934798154564681,0.5913662357262023,0.3518925878136761,-0.4830896335468625,2.473520663548231,0.13603722581215738,0.16725085745394358,-0.21611757016080707,6.892927341166569,-0.7249158875646223,0.3822373090241425,0.2292961177027244,0.13603722581215738,-0.08614306228071349,-0.21611757016080707,0.5024324884152008,1.187095944623876,-0.053998930248529343,0.00987983300086082,-0.21611757016080707,-0.9750783788289236,-0.7249158875646223,-0.15084783616861905,0.2601301997513227,-0.31510754893352083,-0.15084783616861905,-1.196679560306342,-0.2489679916884096,-0.9027126733824001,0.44256943928456016,0.7950034180823421,1.6387032656167018,-0.5857510002982927,0.16725085745394358,-1.196679560306342,-1.9904504283902635,1.8679983625689434,0.8236658353112523,-0.41543726115414226,0.16725085745394358,-0.21611757016080707,-0.2489679916884096,2.2605480296054683,-0.34839980353590916,-0.1184255560889291,0.9654303155685332,-0.021991758289780373,2.473520663548231,0.5913662357262023,0.8806784880076532,0.32142726272319516,0.2908401877882903,-1.122043291912447,-0.6202939338075241,0.19833674271283955,0.6500935842589323,-0.021991758289780373,-1.661941288379124,-0.1184255560889291,1.0492822102543629,-0.7955106096971893,0.41246255537526794,0.32142726272319516,4.451123460314389,0.5321907984016734,-0.021991758289780373,2.3321389821141283,1.0770367526339741,0.6500935842589323,-0.5171506389207149,0.07322168259168828,-0.5171506389207149,-0.021991758289780373,0.19833674271283955,1.1046946053418571,-0.21611757016080707,-0.34839980353590916,-0.18341135031770928,0.8236658353112523,-0.053998930248529343,-0.21611757016080707,0.5024324884152008
| 3,120
|
Cardiac muscle contraction
| 6
| 22
| 2.492232
| 0.012694
|
P14927,O14949,P14406,Q9UDW1,P13073,O14548
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
71,14,46,24,28,62
|
62,14,619,1858,1342,936,2174,1794,566,2718,28,46,71,1861,348,190,620,2634,2898,2677,463,24
|
2.473520663548231,4.376094826005348,0.5321907984016734,-0.21611757016080707,0.041617201213464,0.2908401877882903,-0.38184249878506293,-0.18341135031770928,0.5913662357262023,-0.8310679190732748,3.423751167382198,2.749405899890943,2.3795299433115717,-0.21611757016080707,0.9090305091884525,1.3225701226794089,0.5321907984016734,-0.7249158875646223,-1.122043291912447,-0.7601272692699352,0.708380828182735,3.5278117162155356
| 3,120
|
Disproportionate short stature
| 6
| 24
| 2.482997
| 0.013028
|
Q7LGA3,Q6DKJ4,Q9H6U8,Q9UBM7,Q9UHX1,Q15392
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
11,115,120,253,189,31
|
1022,1726,1976,685,1925,938,1985,1291,998,1752,598,2067,31,280,115,11,1443,1064,819,604,2707,120,253,189
|
0.2292961177027244,-0.15084783616861905,-0.2819641358117063,0.4725590568983185,-0.2489679916884096,0.2908401877882903,-0.2819641358117063,0.07322168259168828,0.2601301997513227,-0.15084783616861905,0.5618350360996074,-0.31510754893352083,3.233289173865552,1.0492822102543629,1.8428352501005447,4.7271758244883895,0.00987983300086082,0.2292961177027244,0.3822373090241425,0.5618350360996074,-0.7955106096971893,1.7922768969431322,1.1322565654429038,1.349392434084322
| 3,120
|
Tetrapyrrole binding
| 9
| 15
| 2.475542
| 0.013303
|
Q8WYQ5,Q7KZN9,Q16850,O43169,O00264,Q96EY8,Q9NRV9,Q6UW02,P30519
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
492,400,171,42,479,547,148,119,60
|
479,42,2174,686,1865,60,2638,171,119,400,492,547,606,1578,148
|
0.6792917290732912,2.817007494245751,-0.38184249878506293,0.4725590568983185,-0.21611757016080707,2.4968560374821402,-0.7249158875646223,1.4027702700675502,1.7922768969431322,0.8236658353112523,0.6792917290732912,0.620785416766542,0.5618350360996074,-0.053998930248529343,1.5608189168337658
| 3,120
|
Cation transmembrane transporter activity
| 18
| 75
| 2.41746
| 0.015629
|
P20674,P16615,P30825,P24539,O75947,O75964,Q13423,Q8N4V1,Q70HW3,P00846,Q93050,Q9UDW1,O14548,O43772,P13073,P35670,Q9Y487,P36543
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
190,348,91,76,318,113,147,309,82,21,220,24,62,27,28,154,333,159
|
62,27,1082,318,113,1179,619,21,1858,1342,2299,534,1793,1344,2347,1092,2174,2718,2894,28,348,504,190,459,885,2593,76,1608,91,2634,154,693,159,1423,2898,943,2188,1001,2763,802,2789,2729,2195,2257,2764,2128,147,2449,1367,2267,702,2268,82,400,309,703,1156,2651,1158,220,1568,1707,1573,2334,2906,2151,826,2462,522,1018,24,1780,745,333,2663
|
2.473520663548231,3.423751167382198,0.19833674271283955,0.9654303155685332,1.8428352501005447,0.13603722581215738,0.5321907984016734,3.589666359430854,-0.21611757016080707,0.041617201213464,-0.4491857450646144,0.620785416766542,-0.18341135031770928,0.041617201213464,-0.4830896335468625,0.19833674271283955,-0.38184249878506293,-0.8310679190732748,-1.122043291912447,3.423751167382198,0.9090305091884525,0.6500935842589323,1.3225701226794089,0.708380828182735,0.32142726272319516,-0.6898744907977593,2.2605480296054683,-0.08614306228071349,2.091083091944511,-0.7249158875646223,1.4821804503241371,0.4725590568983185,1.4557970237686562,0.00987983300086082,-1.122043291912447,0.2908401877882903,-0.38184249878506293,0.2601301997513227,-0.8668012449944402,0.3822373090241425,-0.9027126733824001,-0.8310679190732748,-0.38184249878506293,-0.41543726115414226,-0.8668012449944402,-0.34839980353590916,1.5608189168337658,-0.5513705034966245,0.041617201213464,-0.41543726115414226,0.4725590568983185,-0.41543726115414226,2.1883406422631806,0.8236658353112523,0.9934798154564681,0.4725590568983185,0.16725085745394358,-0.7249158875646223,0.16725085745394358,1.2415610633760816,-0.053998930248529343,-0.1184255560889291,-0.053998930248529343,-0.4491857450646144,-1.122043291912447,-0.34839980353590916,0.3822373090241425,-0.5513705034966245,0.6500935842589323,0.2601301997513227,3.5278117162155356,-0.15084783616861905,0.44256943928456016,0.9654303155685332,-0.7249158875646223
| 3,120
|
Regulation of rna splicing
| 33
| 86
| 2.409119
| 0.015991
|
Q13243,Q9Y580,Q5BKZ1,P38159,Q96MU7,Q07021,P98179,Q9H0G5,P22626,P51116,P49736,Q15007,O00422,P35637,P55795,Q9UHX1,Q16629,Q07955,Q14011,Q15637,Q09666,Q9Y2W1,Q96PU8,P61978,P31942,Q15427,P98175,P62995,Q13242,P19338,Q12872,Q9BWF3,Q13595
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,271,669,138,402,263,22,552,276,408,659,163,650,289,537,189,444,441,65,698,696,612,473,337,590,465,726,366,232,230,248,518,127
|
650,1231,2382,1410,2110,1734,1347,1033,3050,2441,1983,230,276,1417,994,1238,1678,1737,590,1800,289,138,659,1140,724,408,945,894,2051,2488,537,337,1810,366,806,726,22,2258,2569,263,1106,441,1621,2532,696,952,248,232,129,1049,902,127,65,1626,2913,163,1886,465,698,444,2069,3004,669,2321,2273,1375,1702,2078,2704,1897,402,473,2545,1901,1213,518,552,1069,1518,830,189,1520,2375,612,271,2750
|
0.5024324884152008,0.10469459248892066,-0.5171506389207149,0.00987983300086082,-0.34839980353590916,-0.15084783616861905,0.041617201213464,0.2292961177027244,-1.9068305814001267,-0.5513705034966245,-0.2819641358117063,1.187095944623876,1.0492822102543629,0.00987983300086082,0.2601301997513227,0.10469459248892066,-0.1184255560889291,-0.15084783616861905,0.5618350360996074,-0.18341135031770928,1.021430170623449,1.6128245467816795,0.5024324884152008,0.16725085745394358,0.44256943928456016,0.7950034180823421,0.2908401877882903,0.32142726272319516,-0.31510754893352083,-0.5857510002982927,0.620785416766542,0.9372808306752206,-0.18341135031770928,0.8806784880076532,0.3822373090241425,0.44256943928456016,3.548477867253594,-0.41543726115414226,-0.6550011407321256,1.0770367526339741,0.19833674271283955,0.737361844928647,-0.08614306228071349,-0.6202939338075241,0.4725590568983185,0.2908401877882903,1.1322565654429038,1.187095944623876,1.6645000841134392,0.2292961177027244,0.32142726272319516,1.690215615872776,2.473520663548231,-0.08614306228071349,-1.1592632785117458,1.4293271889869001,-0.21611757016080707,0.708380828182735,0.4725590568983185,0.737361844928647,-0.31510754893352083,-1.5033848001965395,0.5024324884152008,-0.4491857450646144,-0.41543726115414226,0.041617201213464,-0.1184255560889291,-0.31510754893352083,-0.7955106096971893,-0.21611757016080707,0.8236658353112523,0.708380828182735,-0.6202939338075241,-0.21611757016080707,0.13603722581215738,0.6500935842589323,0.620785416766542,0.2292961177027244,-0.021991758289780373,0.3822373090241425,1.349392434084322,-0.021991758289780373,-0.4830896335468625,0.5618350360996074,1.0770367526339741,-0.8310679190732748
| 3,120
|
Myoclonus
| 14
| 98
| 2.405957
| 0.01613
|
P00374,P50897,Q9ULV3,O75503,Q10713,Q96CU9,Q9Y4G8,Q01105,P00846,O14773,Q13510,P13073,Q96F07,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,66,204,106,77,176,18,146,21,54,25,28,193,57
|
2101,2870,2343,1401,54,2666,2624,106,1731,2110,1979,2668,1857,0,619,21,347,2716,1602,2926,1032,482,536,28,1537,459,460,2180,2783,1542,2830,694,1423,1350,1545,2787,1247,66,892,290,2675,379,2678,486,1251,397,1299,146,758,807,2259,77,2311,900,25,904,57,1364,1558,3034,2991,2977,3036,1824,2768,1566,860,2080,176,2325,2576,193,1507,2368,1320,1508,1956,710,711,2148,824,1836,607,2151,2884,1323,1273,1325,645,1658,647,204,1907,212,527,18,717,2888
|
-0.34839980353590916,-1.0481825276350252,-0.4830896335468625,0.00987983300086082,2.5201273376889914,-0.7601272692699352,-0.7249158875646223,1.893084846297575,-0.15084783616861905,-0.34839980353590916,-0.2819641358117063,-0.7601272692699352,-0.21611757016080707,6.892927341166569,0.5321907984016734,3.589666359430854,0.9090305091884525,-0.8310679190732748,-0.08614306228071349,-1.196679560306342,0.2292961177027244,0.6792917290732912,0.620785416766542,3.423751167382198,-0.053998930248529343,0.708380828182735,0.708380828182735,-0.38184249878506293,-0.9027126733824001,-0.053998930248529343,-0.9750783788289236,0.4725590568983185,0.00987983300086082,0.041617201213464,-0.053998930248529343,-0.9027126733824001,0.10469459248892066,2.450120794834704,0.32142726272319516,1.021430170623449,-0.7601272692699352,0.8522238923059385,-0.7601272692699352,0.6792917290732912,0.10469459248892066,0.8236658353112523,0.07322168259168828,1.5608189168337658,0.41246255537526794,0.3822373090241425,-0.41543726115414226,2.2605480296054683,-0.4491857450646144,0.32142726272319516,3.4863342700949986,0.32142726272319516,2.5201273376889914,0.041617201213464,-0.053998930248529343,-1.7426041339082696,-1.4254418670885745,-1.3483579845639533,-1.7426041339082696,-0.18341135031770928,-0.8668012449944402,-0.053998930248529343,0.3518925878136761,-0.31510754893352083,1.3761255827105783,-0.4491857450646144,-0.6550011407321256,1.3225701226794089,-0.021991758289780373,-0.4830896335468625,0.07322168259168828,-0.021991758289780373,-0.2489679916884096,0.4725590568983185,0.4725590568983185,-0.34839980353590916,0.3822373090241425,-0.18341135031770928,0.5618350360996074,-0.34839980353590916,-1.0481825276350252,0.07322168259168828,0.10469459248892066,0.07322168259168828,0.5321907984016734,-0.08614306228071349,0.5321907984016734,1.2956579381594955,-0.21611757016080707,1.2686551612087744,0.6500935842589323,3.71210011534424,0.4725590568983185,-1.0481825276350252
| 3,120
|
Inorganic molecular entity transmembrane transporter activity
| 20
| 76
| 2.389083
| 0.01689
|
Q13423,P00846,Q9UDW1,P13073,P35670,P36543,Q9Y277,Q8N4V1,P21796,O14548,Q9Y487,P20674,P24539,O75947,Q8TDW0,Q93050,Q6N075,P16615,O75964,P45880
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
147,21,24,28,154,159,49,309,55,62,333,190,76,318,209,220,95,348,113,114
|
2100,62,2294,318,113,1179,619,21,1858,1342,2299,534,1793,1344,2347,1092,2174,3061,2718,2894,28,348,504,190,459,885,55,2593,76,1608,2634,154,693,159,1423,114,2898,943,2188,1001,2763,802,2789,2729,2195,2257,2764,2491,2128,147,2449,2267,95,702,400,309,703,1156,209,1158,220,2147,1573,2334,2906,2151,522,1018,647,24,1780,745,49,333,2925,2663
|
-0.34839980353590916,2.473520663548231,-0.4491857450646144,0.9654303155685332,1.8428352501005447,0.13603722581215738,0.5321907984016734,3.589666359430854,-0.21611757016080707,0.041617201213464,-0.4491857450646144,0.620785416766542,-0.18341135031770928,0.041617201213464,-0.4830896335468625,0.19833674271283955,-0.38184249878506293,-2.032649954860639,-0.8310679190732748,-1.122043291912447,3.423751167382198,0.9090305091884525,0.6500935842589323,1.3225701226794089,0.708380828182735,0.32142726272319516,2.5201273376889914,-0.6898744907977593,2.2605480296054683,-0.08614306228071349,-0.7249158875646223,1.4821804503241371,0.4725590568983185,1.4557970237686562,0.00987983300086082,1.8428352501005447,-1.122043291912447,0.2908401877882903,-0.38184249878506293,0.2601301997513227,-0.8668012449944402,0.3822373090241425,-0.9027126733824001,-0.8310679190732748,-0.38184249878506293,-0.41543726115414226,-0.8668012449944402,-0.5857510002982927,-0.34839980353590916,1.5608189168337658,-0.5513705034966245,-0.41543726115414226,2.0665902618265855,0.4725590568983185,0.8236658353112523,0.9934798154564681,0.4725590568983185,0.16725085745394358,1.2686551612087744,0.16725085745394358,1.2415610633760816,-0.34839980353590916,-0.053998930248529343,-0.4491857450646144,-1.122043291912447,-0.34839980353590916,0.6500935842589323,0.2601301997513227,0.5321907984016734,3.5278117162155356,-0.15084783616861905,0.44256943928456016,2.681266849929279,0.9654303155685332,-1.1592632785117458,-0.7249158875646223
| 3,120
|
Negative regulation of mrna splicing via spliceosome
| 8
| 16
| 2.363236
| 0.018116
|
O00422,P38159,Q13242,Q07021,P61978,Q12872,P22626,Q16629
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
650,138,232,263,337,248,276,444
|
650,1410,276,994,1238,138,337,726,263,1621,248,232,1049,1886,444,1213
|
0.5024324884152008,0.00987983300086082,1.0492822102543629,0.2601301997513227,0.10469459248892066,1.6128245467816795,0.9372808306752206,0.44256943928456016,1.0770367526339741,-0.08614306228071349,1.1322565654429038,1.187095944623876,0.2292961177027244,-0.21611757016080707,0.737361844928647,0.13603722581215738
| 3,120
|
Proton transporting two sector atpase complex
| 7
| 21
| 2.349675
| 0.01879
|
P24539,O75964,P00846,Q93050,Q96IX5,Q9Y487,P36543
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
76,113,21,220,61,333,159
|
1411,318,113,21,534,459,885,76,1608,693,159,1423,943,2763,802,2789,699,220,61,1780,333
|
0.00987983300086082,0.9654303155685332,1.8428352501005447,3.589666359430854,0.620785416766542,0.708380828182735,0.32142726272319516,2.2605480296054683,-0.08614306228071349,0.4725590568983185,1.4557970237686562,0.00987983300086082,0.2908401877882903,-0.8668012449944402,0.3822373090241425,-0.9027126733824001,0.4725590568983185,1.2415610633760816,2.4968560374821402,-0.15084783616861905,0.9654303155685332
| 3,120
|
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
| 6
| 16
| 2.339878
| 0.01929
|
Q02818,O76024,Q07065,Q15293,O43852,Q13217
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
32,407,37,249,213,443
|
1334,213,407,2592,2717,2240,1095,1288,32,37,443,1754,249,467,1636,1164
|
0.041617201213464,1.2415610633760816,0.7950034180823421,-0.6898744907977593,-0.8310679190732748,-0.41543726115414226,0.19833674271283955,0.07322168259168828,3.1688713554682066,3.01668582144507,0.737361844928647,-0.15084783616861905,1.1322565654429038,0.708380828182735,-0.08614306228071349,0.16725085745394358
| 3,120
|
Abnormality of the knee
| 18
| 83
| 2.314986
| 0.020614
|
Q96L58,Q9NR77,Q8TD16,P08236,Q9NX62,Q96PU5,O00459,P21964,Q7LGA3,Q96AY3,Q8N806,O95831,P37268,P21912,Q15056,Q13510,O75340,P36543
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
194,131,201,436,239,8,137,322,11,371,470,108,20,395,279,25,255,159
|
137,2869,1401,2825,2225,653,2032,2382,255,1976,1854,1668,1978,108,936,436,2806,938,883,2442,1289,395,322,1930,886,1539,2896,2783,2351,2722,159,1138,20,658,3039,2637,1295,1805,2398,1684,1300,949,2933,2570,2128,1431,2311,25,1690,2067,1559,279,1260,467,1058,11,1443,1635,1201,735,470,201,967,1319,2417,371,819,194,1567,8,2460,131,2463,2819,239,2660,2217,1782,2289,2097,2821,2750,2888
|
1.6128245467816795,-1.0481825276350252,0.00987983300086082,-0.9750783788289236,-0.41543726115414226,0.5024324884152008,-0.31510754893352083,-0.5171506389207149,1.1046946053418571,-0.2819641358117063,-0.21611757016080707,-0.1184255560889291,-0.2819641358117063,1.8679983625689434,0.2908401877882903,0.737361844928647,-0.938804329471579,0.2908401877882903,0.32142726272319516,-0.5513705034966245,0.07322168259168828,0.8236658353112523,0.9654303155685332,-0.2489679916884096,0.32142726272319516,-0.053998930248529343,-1.122043291912447,-0.9027126733824001,-0.4830896335468625,-0.8310679190732748,1.4557970237686562,0.16725085745394358,3.6306648569855366,0.5024324884152008,-1.783293025849484,-0.7249158875646223,0.07322168259168828,-0.18341135031770928,-0.5171506389207149,-0.1184255560889291,0.07322168259168828,0.2908401877882903,-1.196679560306342,-0.6550011407321256,-0.34839980353590916,0.00987983300086082,-0.4491857450646144,3.4863342700949986,-0.1184255560889291,-0.31510754893352083,-0.053998930248529343,1.0492822102543629,0.10469459248892066,0.708380828182735,0.2292961177027244,4.7271758244883895,0.00987983300086082,-0.08614306228071349,0.13603722581215738,0.44256943928456016,0.708380828182735,1.2956579381594955,0.2908401877882903,0.07322168259168828,-0.5171506389207149,0.8806784880076532,0.3822373090241425,1.3225701226794089,-0.053998930248529343,4.924534440260118,-0.5513705034966245,1.6645000841134392,-0.5513705034966245,-0.938804329471579,1.187095944623876,-0.7249158875646223,-0.38184249878506293,-0.15084783616861905,-0.41543726115414226,-0.31510754893352083,-0.938804329471579,-0.8310679190732748,-1.0481825276350252
| 3,120
|
Positive regulation of rna splicing
| 7
| 22
| 2.313552
| 0.020692
|
Q14011,Q13243,P62995,P38159,P19338,P98179,Q13595
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,129,366,138,230,22,127
|
2382,1734,1033,230,1417,994,1678,138,2051,366,22,2532,129,902,127,65,465,1702,1897,1518,2375,612
|
-0.5171506389207149,-0.15084783616861905,0.2292961177027244,1.187095944623876,0.00987983300086082,0.2601301997513227,-0.1184255560889291,1.6128245467816795,-0.31510754893352083,0.8806784880076532,3.548477867253594,-0.6202939338075241,1.6645000841134392,0.32142726272319516,1.690215615872776,2.473520663548231,0.708380828182735,-0.1184255560889291,-0.21611757016080707,-0.021991758289780373,-0.4830896335468625,0.5618350360996074
| 3,120
|
Positional foot deformity
| 28
| 101
| 2.312267
| 0.020763
|
Q9NR77,P04792,Q5H8A4,P42356,Q8NCH0,Q96DF8,Q15907,P36543,Q15392,P52788,Q8TAA9,Q9UGM6,Q9H267,P07196,Q9UHX1,Q9Y487,Q96L58,Q8TD16,P08236,P21964,P61978,Q15427,Q69YQ0,Q96AY3,Q8WYQ5,Q9H6U8,Q9UBM7,Q03001
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
131,17,398,278,156,157,29,159,31,290,174,455,452,59,189,333,194,201,436,322,337,465,224,371,492,120,253,381
|
2869,1401,878,2825,2972,1594,653,987,1916,1976,2555,1731,1529,1179,1473,1028,17,936,59,436,2755,1348,2519,2039,1797,2442,322,1540,2784,159,1138,1423,1739,278,2637,1937,290,1805,1993,337,726,1300,2570,381,2402,2311,2313,1558,1753,31,465,29,398,224,2686,1055,1498,1058,1443,2768,156,1064,2839,860,174,2649,201,2414,492,967,2417,1503,371,157,194,1567,1320,2707,452,1068,120,2980,609,2462,677,131,1017,2620,253,455,189,1459,2217,745,1586,2289,1399,527,333,2750,2888
|
-1.0481825276350252,0.00987983300086082,0.32142726272319516,-0.9750783788289236,-1.3483579845639533,-0.08614306228071349,0.5024324884152008,0.2601301997513227,-0.2489679916884096,-0.2819641358117063,-0.6550011407321256,-0.15084783616861905,-0.053998930248529343,0.13603722581215738,-0.021991758289780373,0.2292961177027244,3.73234337597373,0.2908401877882903,2.4968560374821402,0.737361844928647,-0.8668012449944402,0.041617201213464,-0.6202939338075241,-0.31510754893352083,-0.18341135031770928,-0.5513705034966245,0.9654303155685332,-0.053998930248529343,-0.9027126733824001,1.4557970237686562,0.16725085745394358,0.00987983300086082,-0.15084783616861905,1.0492822102543629,-0.7249158875646223,-0.2489679916884096,1.021430170623449,-0.18341135031770928,-0.2819641358117063,0.9372808306752206,0.44256943928456016,0.07322168259168828,-0.6550011407321256,0.8522238923059385,-0.5171506389207149,-0.4491857450646144,-0.4491857450646144,-0.053998930248529343,-0.15084783616861905,3.233289173865552,0.708380828182735,3.3396104265019546,0.8236658353112523,1.2143749069155765,-0.7601272692699352,0.2292961177027244,-0.021991758289780373,0.2292961177027244,0.00987983300086082,-0.8668012449944402,1.4821804503241371,0.2292961177027244,-0.9750783788289236,0.3518925878136761,1.3761255827105783,-0.7249158875646223,1.2956579381594955,-0.5171506389207149,0.6792917290732912,0.2908401877882903,-0.5171506389207149,-0.021991758289780373,0.8806784880076532,1.4821804503241371,1.3225701226794089,-0.053998930248529343,0.07322168259168828,-0.7955106096971893,0.737361844928647,0.2292961177027244,1.7922768969431322,-1.3483579845639533,0.5618350360996074,-0.5513705034966245,0.5024324884152008,1.6645000841134392,0.2601301997513227,-0.6898744907977593,1.1322565654429038,0.737361844928647,1.349392434084322,0.00987983300086082,-0.38184249878506293,0.44256943928456016,-0.053998930248529343,-0.41543726115414226,0.041617201213464,0.6500935842589323,0.9654303155685332,-0.8310679190732748,-1.0481825276350252
| 3,120
|
Positive regulation of mrna splicing via spliceosome
| 6
| 16
| 2.309585
| 0.020911
|
Q14011,P62995,P38159,P19338,P98179,Q13595
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,366,138,230,22,127
|
1734,1033,230,1678,138,2051,366,22,2532,902,127,65,465,1897,2375,612
|
-0.15084783616861905,0.2292961177027244,1.187095944623876,-0.1184255560889291,1.6128245467816795,-0.31510754893352083,0.8806784880076532,3.548477867253594,-0.6202939338075241,0.32142726272319516,1.690215615872776,2.473520663548231,0.708380828182735,-0.21611757016080707,-0.4830896335468625,0.5618350360996074
| 3,120
|
Aplasia hypoplasia of toe
| 12
| 32
| 2.273044
| 0.023024
|
Q69YQ0,Q9NX62,Q96PZ0,Q7LGA3,Q8N806,Q5JRA6,O75648,Q5H8A4,Q13510,P13073,Q9UHX1,Q9UBM7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
224,239,74,11,470,467,245,398,25,28,189,253
|
2342,2344,245,1179,2754,1473,1923,1028,1925,28,2442,2390,1866,1350,1001,2402,2313,25,1365,465,398,467,224,11,1444,2968,470,74,1068,239,253,189
|
-0.4830896335468625,-0.4830896335468625,1.1322565654429038,0.13603722581215738,-0.8668012449944402,-0.021991758289780373,-0.2489679916884096,0.2292961177027244,-0.2489679916884096,3.423751167382198,-0.5513705034966245,-0.5171506389207149,-0.21611757016080707,0.041617201213464,0.2601301997513227,-0.5171506389207149,-0.4491857450646144,3.4863342700949986,0.041617201213464,0.708380828182735,0.8236658353112523,0.708380828182735,1.2143749069155765,4.7271758244883895,0.00987983300086082,-1.3101312220661574,0.708380828182735,2.3321389821141283,0.2292961177027244,1.187095944623876,1.1322565654429038,1.349392434084322
| 3,120
|
Insulin resistance
| 9
| 18
| 2.233839
| 0.025494
|
O76024,P17096,P28340,Q96MF7,Q03252,Q9Y6M1,Q8NC56,O75844,P31751
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
407,221,323,604,758,682,90,124,589
|
1847,1525,1854,124,407,787,1028,221,1286,323,589,1935,1615,758,90,604,1014,682
|
-0.21611757016080707,-0.053998930248529343,-0.21611757016080707,1.7158504672662176,0.7950034180823421,0.3822373090241425,0.2292961177027244,1.2143749069155765,0.07322168259168828,0.9654303155685332,0.5618350360996074,-0.2489679916884096,-0.08614306228071349,0.41246255537526794,2.115504048314232,0.5618350360996074,0.2601301997513227,0.5024324884152008
| 3,120
|
Oxidase
| 8
| 21
| 2.223364
| 0.026191
|
P20674,O15260,P36551,O43169,O43819,P11310,P14406,O14548
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
190,287,133,42,229,196,46,62
|
62,2222,287,42,229,1731,2627,2718,196,2239,46,1861,190,2911,133,506,341,1944,1057,1759,2800
|
2.473520663548231,-0.41543726115414226,1.021430170623449,2.817007494245751,1.187095944623876,-0.15084783616861905,-0.7249158875646223,-0.8310679190732748,1.2956579381594955,-0.41543726115414226,2.749405899890943,-0.21611757016080707,1.3225701226794089,-1.1592632785117458,1.6387032656167018,0.6500935842589323,0.9372808306752206,-0.2489679916884096,0.2292961177027244,-0.15084783616861905,-0.9027126733824001
| 3,120
|
Distal muscle weakness
| 14
| 65
| 2.206774
| 0.02733
|
Q9NR77,Q86U42,Q8TD16,P36551,Q9BQT8,P35637,P41440,O95831,Q99720,P04792,P00846,P22626,P07196,O75340
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
131,383,201,133,39,289,44,108,16,17,21,276,59,255
|
1592,785,2751,255,1978,787,1855,108,21,1028,17,936,59,1606,1347,797,1797,1930,276,1737,2115,289,133,2246,1424,44,1292,1869,1545,2187,2599,2447,379,2676,2398,2728,1995,1554,2128,1431,1688,953,1152,1364,1690,1003,1110,2072,1309,2320,383,491,2649,201,2798,2904,1161,16,39,131,2468,1399,717,2924,558
|
-0.08614306228071349,0.3822373090241425,-0.8668012449944402,1.1046946053418571,-0.2819641358117063,0.3822373090241425,-0.21611757016080707,1.8679983625689434,3.589666359430854,0.2292961177027244,3.73234337597373,0.2908401877882903,2.4968560374821402,-0.08614306228071349,0.041617201213464,0.3822373090241425,-0.18341135031770928,-0.2489679916884096,1.0492822102543629,-0.15084783616861905,-0.34839980353590916,1.021430170623449,1.6387032656167018,-0.41543726115414226,0.00987983300086082,2.7945327251855265,0.07322168259168828,-0.21611757016080707,-0.053998930248529343,-0.38184249878506293,-0.6898744907977593,-0.5513705034966245,0.8522238923059385,-0.7601272692699352,-0.5171506389207149,-0.8310679190732748,-0.2819641358117063,-0.053998930248529343,-0.34839980353590916,0.00987983300086082,-0.1184255560889291,0.2908401877882903,0.16725085745394358,0.041617201213464,-0.1184255560889291,0.2601301997513227,0.19833674271283955,-0.31510754893352083,0.07322168259168828,-0.4491857450646144,0.8522238923059385,0.6792917290732912,-0.7249158875646223,1.2956579381594955,-0.9027126733824001,-1.122043291912447,0.16725085745394358,3.8727794768615476,2.97270991371045,1.6645000841134392,-0.5513705034966245,0.041617201213464,0.4725590568983185,-1.1592632785117458,0.620785416766542
| 3,120
|
Abnormal neuron morphology
| 8
| 29
| 2.204286
| 0.027504
|
P35637,Q9UHD9,Q92804,Q99720,Q9UQN3,Q13510,P22626,Q15165
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
289,140,251,16,212,25,276,30
|
1081,1978,1855,3001,1347,1798,1930,276,1737,289,1292,1142,1993,2398,1688,953,25,1152,30,1945,491,401,251,711,16,1268,2094,140,212
|
0.19833674271283955,-0.2819641358117063,-0.21611757016080707,-1.5033848001965395,0.041617201213464,-0.18341135031770928,-0.2489679916884096,1.0492822102543629,-0.15084783616861905,1.021430170623449,0.07322168259168828,0.16725085745394358,-0.2819641358117063,-0.5171506389207149,-0.1184255560889291,0.2908401877882903,3.4863342700949986,0.16725085745394358,3.3184489550204734,-0.2489679916884096,0.6792917290732912,0.8236658353112523,1.1322565654429038,0.4725590568983185,3.8727794768615476,0.10469459248892066,-0.31510754893352083,1.6128245467816795,1.2686551612087744
| 3,120
|
Response to cold
| 7
| 11
| 2.189872
| 0.028534
|
Q14011,P54652,P04179,P49748,P20020,P11310,Q13217
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,425,532,506,504,196,443
|
619,532,1283,2236,196,883,504,506,425,443,65
|
0.5321907984016734,0.620785416766542,0.07322168259168828,-0.41543726115414226,1.2956579381594955,0.32142726272319516,0.6500935842589323,0.6500935842589323,0.7662357292792964,0.737361844928647,2.473520663548231
| 3,120
|
Mitochondrial calcium ion transport
| 11
| 17
| 2.18194
| 0.029114
|
P35232,Q99623,Q8NE86,Q96TA2,Q10713,Q9Y277,Q9H300,Q8WWC4,P45880,Q9Y4W6,P21796
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
721,372,703,867,77,49,739,577,114,717,55
|
2554,1179,55,721,114,77,1764,703,577,1647,867,372,2613,739,874,49,717
|
-0.6550011407321256,0.13603722581215738,2.5201273376889914,0.44256943928456016,1.8428352501005447,2.2605480296054683,-0.15084783616861905,0.4725590568983185,0.5913662357262023,-0.08614306228071349,0.3518925878136761,0.8806784880076532,-0.6898744907977593,0.44256943928456016,0.3518925878136761,2.681266849929279,0.4725590568983185
| 3,120
|
Hydrogen ion transport
| 10
| 19
| 2.178918
| 0.029338
|
P36543,P06576,P24539,O75947,O75964,P00846,Q93050,P21281,Q9Y487,Q15904
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
159,534,76,318,113,21,220,459,333,699
|
318,113,21,534,459,885,76,1608,693,159,1423,943,2763,802,2789,699,220,1780,333
|
0.9654303155685332,1.8428352501005447,3.589666359430854,0.620785416766542,0.708380828182735,0.32142726272319516,2.2605480296054683,-0.08614306228071349,0.4725590568983185,1.4557970237686562,0.00987983300086082,0.2908401877882903,-0.8668012449944402,0.3822373090241425,-0.9027126733824001,0.4725590568983185,1.2415610633760816,-0.15084783616861905,0.9654303155685332
| 3,120
|
Ferroptosis
| 6
| 24
| 2.173411
| 0.029749
|
Q9NZ45,P04792,Q9Y277,P45880,P37268,P04035
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
105,17,49,114,20,274
|
1974,935,1341,347,274,2851,17,1092,686,2039,1242,20,114,1351,1293,2449,2643,2451,1367,1437,2906,105,931,49
|
-0.2819641358117063,0.2908401877882903,0.041617201213464,0.9090305091884525,1.0492822102543629,-1.0115370284074634,3.73234337597373,0.19833674271283955,0.4725590568983185,-0.31510754893352083,0.10469459248892066,3.6306648569855366,1.8428352501005447,0.041617201213464,0.07322168259168828,-0.5513705034966245,-0.7249158875646223,-0.5513705034966245,0.041617201213464,0.00987983300086082,-1.122043291912447,1.9180952538057965,0.32142726272319516,2.681266849929279
| 3,120
|
Cristae formation
| 9
| 20
| 2.172269
| 0.029835
|
Q5XKP0,Q9NX63,Q9Y512,P24539,O75947,Q6UXV4,O75964,P00846,Q13505
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
223,500,406,76,318,511,113,21,125
|
1854,318,113,21,534,76,1608,693,1738,943,2763,802,125,700,223,511,2843,1964,500,406
|
-0.21611757016080707,0.9654303155685332,1.8428352501005447,3.589666359430854,0.620785416766542,2.2605480296054683,-0.08614306228071349,0.4725590568983185,-0.15084783616861905,0.2908401877882903,-0.8668012449944402,0.3822373090241425,1.7158504672662176,0.4725590568983185,1.2143749069155765,0.6500935842589323,-0.9750783788289236,-0.2489679916884096,0.6792917290732912,0.8236658353112523
| 3,120
|
Mitochondrial complex iv assembly
| 6
| 13
| 2.161585
| 0.03065
|
Q9Y2R0,P20674,O43819,P14406,P13073,Q9Y6N1
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
1,190,229,46,28,334
|
2101,229,619,566,2718,28,46,1861,190,400,3060,1,334
|
-0.34839980353590916,1.187095944623876,0.5321907984016734,0.5913662357262023,-0.8310679190732748,3.423751167382198,2.749405899890943,-0.21611757016080707,1.3225701226794089,0.8236658353112523,-1.9904504283902635,6.045490941497649,0.9654303155685332
| 3,120
|
Clumsiness
| 6
| 22
| 2.146458
| 0.031836
|
Q9NR77,O75503,O43819,O14773,Q13510,P35670
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
131,106,229,54,25,154
|
2292,54,1081,2294,229,106,936,2783,1737,154,1350,807,953,25,341,510,1309,2839,1956,131,1658,2023
|
-0.4491857450646144,2.5201273376889914,0.19833674271283955,-0.4491857450646144,1.187095944623876,1.893084846297575,0.2908401877882903,-0.9027126733824001,-0.15084783616861905,1.4821804503241371,0.041617201213464,0.3822373090241425,0.2908401877882903,3.4863342700949986,0.9372808306752206,0.6500935842589323,0.07322168259168828,-0.9750783788289236,-0.2489679916884096,1.6645000841134392,-0.08614306228071349,-0.2819641358117063
| 3,120
|
Subsets and Splits
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