term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tetrapyrrole binding
| 9
| 16
| 3.415534
| 0.000637
|
Q9H7Z7,P09601,O43169,Q16850,O00264,P53701,O15173,P30519,Q96EY8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
34,169,74,140,115,215,120,25,227
|
115,120,74,823,169,2311,25,215,140,316,1237,1022,227,1084,34,1122
|
1.8172767653783097,1.7997981488475483,2.2613651972231907,0.44930601055840114,1.515840391838553,-0.46605986346971,3.2649229530203527,1.297292869739083,1.6765758036559943,1.0736179845718188,0.18272500423106916,0.32727353035340734,1.278853689347875,0.286217363258279,2.9250567577732913,0.26561689337391103
| 3,210
|
Anion transport
| 13
| 65
| 3.356173
| 0.00079
|
Q9H2D1,O43681,P30536,O00400,Q9UHG3,P53985,Q9UBX3,P21796,P45880,Q7L0J3,P08183,Q9Y619,Q99808
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,104,91,43,14,145,50,19,52,84,113,59,156
|
275,43,565,1867,104,2134,1036,478,2050,2627,568,2180,2553,335,113,2080,3142,851,467,2686,735,2019,19,2341,1422,91,2083,267,52,3048,2445,145,1658,887,775,1799,801,2284,1048,3184,2671,1200,84,163,526,811,156,1937,1251,1086,1,1772,1941,1969,746,844,686,50,14,2877,506,1091,59,1688,2760
|
1.1487666995177788,2.687053265961324,0.6884687739263295,-0.1787578934323262,1.9387760747315386,-0.3543756565400391,0.30676947108334135,0.7862799512775219,-0.28808392260207233,-0.7172980550040869,0.6884687739263295,-0.37659150480827835,-0.6479983733197957,1.016858162020565,1.8521420832959734,-0.31012230394858126,-2.030379226705189,0.4290838414759394,0.8057169414204521,-0.7638342514312623,0.5297381122387874,-0.2661038286652666,3.565072073980479,-0.48858049757519073,0.05688083594047554,2.092859600557418,-0.31012230394858126,1.1674604442373642,2.509065367944047,-1.42092054737106,-0.556518486029154,1.6588461750842975,-0.0708373510934119,0.40881543685910227,0.4896128041999829,-0.13542382527329797,0.4694822353754309,-0.44360111347426245,0.30676947108334135,-2.7908471566158775,-0.740532149740219,0.20352212550695528,2.160595878265183,1.5517889434452048,0.7472814698483077,0.4694822353754309,1.6054641390302427,-0.20050904201939973,0.18272500423106916,0.286217363258279,5.424065052068769,-0.1138401084971145,-0.20050904201939973,-0.22231680626932795,0.5297381122387874,0.44930601055840114,0.5895906935815504,2.557906632557138,3.886275851199562,-0.9767075535898113,0.7668015426370355,0.286217363258279,2.4435871616487934,-0.0708373510934119,-0.8341541839153083
| 3,210
|
Nonalcoholic fatty liver disease
| 23
| 48
| 3.284746
| 0.001021
|
Q9Y6M9,P14406,P63000,O95298,Q9P0J0,O43676,Q86Y39,P31040,P51970,P60953,P49840,O95299,P22695,Q9UDW1,O14949,O75380,P00403,P49841,O75306,P31930,P14854,P20674,P13073
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
530,5,636,282,33,41,174,435,573,574,572,690,569,75,76,711,334,592,464,220,229,498,370
|
996,2657,1484,76,41,1281,1416,464,711,1487,282,690,334,1455,823,2685,1873,370,5,229,875,1289,2603,498,1317,569,3117,435,1699,220,717,2383,1165,1426,572,592,573,2691,574,636,2193,2887,2500,174,985,33,75,530
|
0.32727353035340734,-0.740532149740219,0.014520145426408674,2.2446389541407687,2.814646690863611,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,1.1300357877506997,0.5696841825408305,1.016858162020565,0.03572669165067375,0.44930601055840114,-0.7638342514312623,-0.1787578934323262,0.9597505084681618,4.972198060062475,1.2603787307732723,0.40881543685910227,0.14098048384438178,-0.6941314197209414,0.7668015426370355,0.12003241207649194,0.6884687739263295,-1.8124742250552148,0.8444676370207627,-0.09231141282339332,1.278853689347875,0.5497334133991656,-0.5111634909229179,0.22426959652252174,0.05688083594047554,0.6884687739263295,0.6687795395939293,0.6884687739263295,-0.7638342514312623,0.6884687739263295,0.6292720233130275,-0.37659150480827835,-1.0007215188288232,-0.6021287719704128,1.4797581820627799,0.34772985125492284,2.956395767747345,2.2613651972231907,0.7472814698483077
| 3,210
|
Anion transmembrane transport
| 8
| 38
| 3.141561
| 0.00168
|
Q9H2D1,Q9UHG3,P53985,Q9UBX3,P21796,P45880,P08183,Q9Y619
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,14,145,50,19,52,113,59
|
1867,2134,478,2050,2627,2180,2553,113,2080,467,2686,19,2083,267,52,3048,2445,145,1658,887,775,1799,801,1048,163,526,1937,1,1941,1969,746,50,14,2877,506,1091,59,2760
|
-0.1787578934323262,-0.3543756565400391,0.7862799512775219,-0.28808392260207233,-0.7172980550040869,-0.37659150480827835,-0.6479983733197957,1.8521420832959734,-0.31012230394858126,0.8057169414204521,-0.7638342514312623,3.565072073980479,-0.31012230394858126,1.1674604442373642,2.509065367944047,-1.42092054737106,-0.556518486029154,1.6588461750842975,-0.0708373510934119,0.40881543685910227,0.4896128041999829,-0.13542382527329797,0.4694822353754309,0.30676947108334135,1.5517889434452048,0.7472814698483077,-0.20050904201939973,5.424065052068769,-0.20050904201939973,-0.22231680626932795,0.5297381122387874,2.557906632557138,3.886275851199562,-0.9767075535898113,0.7668015426370355,0.286217363258279,2.4435871616487934,-0.8341541839153083
| 3,210
|
Respirasome
| 18
| 44
| 3.097823
| 0.001949
|
Q9P0J0,P31930,Q9Y6M9,P14406,P14854,O43676,Q9UDW1,Q6DKK2,O14949,Q86Y39,P20674,P13073,P00403,P03886,O95298,O75306,P31040,P51970
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
33,220,530,5,229,41,75,439,76,174,498,370,334,152,282,464,435,573
|
996,2657,76,41,1281,1416,464,711,1487,282,690,334,152,823,2685,1873,370,5,229,875,1289,2603,498,1317,569,3117,435,220,2383,1426,573,2691,1504,2887,2500,439,1237,174,762,33,75,1647,2789,530
|
0.32727353035340734,-0.740532149740219,2.2446389541407687,2.814646690863611,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,1.1300357877506997,0.5696841825408305,1.016858162020565,1.6232905049437316,0.44930601055840114,-0.7638342514312623,-0.1787578934323262,0.9597505084681618,4.972198060062475,1.2603787307732723,0.40881543685910227,0.14098048384438178,-0.6941314197209414,0.7668015426370355,0.12003241207649194,0.6884687739263295,-1.8124742250552148,0.8444676370207627,1.278853689347875,-0.5111634909229179,0.05688083594047554,0.6884687739263295,-0.7638342514312623,0.014520145426408674,-1.0007215188288232,-0.6021287719704128,0.8444676370207627,0.18272500423106916,1.4797581820627799,0.5096980023516975,2.956395767747345,2.2613651972231907,-0.04941754059447337,-0.8577339369682366,0.7472814698483077
| 3,210
|
Sphingolipid biosynthetic process
| 8
| 15
| 3.028315
| 0.002459
|
O95470,P27544,O15121,Q96G23,P04062,Q16739,Q13510,Q06136
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
35,296,108,172,325,44,304,155
|
108,611,1825,35,325,944,296,155,304,44,1989,172,1646,377,2678
|
1.8868858346923807,0.64904737623524,-0.15706295482882135,2.9093530775549494,1.0358164604588085,0.36813874070508046,1.1112675033149844,1.6054641390302427,1.092461638717988,2.6709959483183634,-0.24418159668346107,1.497816080363346,-0.04941754059447337,0.9597505084681618,-0.740532149740219
| 3,210
|
Tclin
| 34
| 86
| 3.025023
| 0.002486
|
Q9Y6M9,Q06203,Q9Y2I1,P11802,P04035,P00390,P03886,O95298,Q99808,Q9P0J0,O43676,Q16739,P23921,Q86Y39,P21964,P49721,P04818,O95299,P51970,P49840,P48735,P38435,Q7L0J3,O75380,P20618,P49841,P04150,O75306,P05023,P00374,Q02127,P26358,O43924,P15121
|
Drugs and Diseases
|
Pharos IDG Category
|
pharos_protein_category
|
530,383,405,144,396,655,152,282,156,33,41,44,550,174,301,186,185,690,573,572,571,207,84,711,469,592,465,464,734,733,482,356,369,371
|
996,2657,41,1281,369,1416,464,711,1487,282,690,733,655,2705,1490,152,396,465,185,734,2416,2706,2553,2764,2852,2055,1693,942,1694,1695,2135,2477,2497,144,1004,1697,371,2603,469,2137,301,1578,550,1353,356,907,3117,1290,1354,207,1702,571,186,1426,572,592,1585,573,1358,1658,2691,2256,1388,973,482,1623,383,1503,2557,1434,2887,44,2500,778,84,174,835,2289,2539,156,1056,2409,2206,33,405,530
|
0.32727353035340734,-0.740532149740219,2.814646690863611,0.14098048384438178,0.9597505084681618,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,1.1300357877506997,0.5696841825408305,0.5297381122387874,0.6094532176877998,-0.7872049149016607,0.014520145426408674,1.6232905049437316,0.9214825561524033,0.8057169414204521,1.4253812176403144,0.5297381122387874,-0.5338093246549072,-0.7872049149016607,-0.6479983733197957,-0.8577339369682366,-0.9527674967759283,-0.28808392260207233,-0.09231141282339332,0.36813874070508046,-0.09231141282339332,-0.09231141282339332,-0.3543756565400391,-0.5792914685282397,-0.6021287719704128,1.6588461750842975,0.32727353035340734,-0.09231141282339332,0.9597505084681618,-0.6941314197209414,0.8057169414204521,-0.3543756565400391,1.092461638717988,-0.028051602989249587,0.7081153372030551,0.09903334462182867,0.9788254062828049,0.3885005023995106,-1.8124742250552148,0.14098048384438178,0.09903334462182867,1.3340646601393549,-0.09231141282339332,0.6884687739263295,1.4253812176403144,0.05688083594047554,0.6884687739263295,0.6687795395939293,-0.028051602989249587,0.6884687739263295,0.09903334462182867,-0.0708373510934119,-0.7638342514312623,-0.42120377836259065,0.07798293576717874,0.34772985125492284,0.7862799512775219,-0.04941754059447337,0.9406363002425452,0.014520145426408674,-0.6479983733197957,0.05688083594047554,-1.0007215188288232,2.6709959483183634,-0.6021287719704128,0.4896128041999829,2.160595878265183,1.4797581820627799,0.44930601055840114,-0.44360111347426245,-0.6250309026232277,1.6054641390302427,0.30676947108334135,-0.5111634909229179,-0.37659150480827835,2.956395767747345,0.9214825561524033,0.7472814698483077
| 3,210
|
Mitochondrial transmembrane transport
| 6
| 50
| 3.01559
| 0.002565
|
Q99595,Q9H2D1,O43772,Q9BSK2,P21796,Q9Y619
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,66,9,19,59
|
1255,937,66,333,1977,2050,479,67,587,2016,1742,1222,2180,2993,3100,467,2686,19,312,1318,3037,2343,3113,912,2445,1841,1500,887,860,1047,440,2699,1330,702,2734,2988,526,0,2066,1937,9,1,1941,1969,1028,2919,2877,2624,1278,59
|
0.16187790183882575,0.36813874070508046,2.311381403119757,1.016858162020565,-0.24418159668346107,-0.28808392260207233,0.7862799512775219,2.311381403119757,0.6687795395939293,-0.2661038286652666,-0.1138401084971145,0.18272500423106916,-0.37659150480827835,-1.2202811138168626,-1.7059780565784959,0.8057169414204521,-0.7638342514312623,3.565072073980479,1.0736179845718188,0.12003241207649194,-1.3702552416869775,-0.48858049757519073,-1.785701460422968,0.3885005023995106,-0.556518486029154,-0.15706295482882135,0.014520145426408674,0.40881543685910227,0.4290838414759394,0.30676947108334135,0.8444676370207627,-0.7638342514312623,0.12003241207649194,0.5696841825408305,-0.8106447024352365,-1.195572223965075,0.7472814698483077,6.587934544608236,-0.28808392260207233,-0.20050904201939973,4.268651553761713,5.424065052068769,-0.20050904201939973,-0.22231680626932795,0.32727353035340734,-1.0489737282202127,-0.9767075535898113,-0.6941314197209414,0.16187790183882575,2.4435871616487934
| 3,210
|
Mitochondrial transport
| 25
| 82
| 3.015286
| 0.002567
|
Q9Y5J9,Q99595,Q5JRX3,Q9NS69,Q9Y584,Q8N4H5,O95376,Q9P0J0,Q10713,Q15070,Q9UBX3,P45880,P23786,P30405,P49840,O43772,O75964,O00170,P52789,O94826,P12235,P04637,P30536,Q96EK5,O75947
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
529,0,257,6,13,402,533,33,171,45,50,52,312,434,572,66,67,72,210,587,467,466,91,94,479
|
72,848,1255,3094,937,66,903,1977,479,67,587,2658,533,2017,1742,1222,466,2180,2993,1654,2082,3100,467,1419,312,1318,3037,434,2898,91,1356,2343,2420,52,3113,1191,773,572,592,912,2384,210,1104,1841,1500,2447,2193,171,45,860,777,1047,1989,257,2671,1714,760,1632,402,3080,702,2988,94,2363,0,2065,2782,1028,1524,6,33,993,1151,50,2542,2877,2624,2789,2172,872,13,529
|
2.2780642718897113,0.4290838414759394,0.16187790183882575,-1.65331482085283,0.36813874070508046,2.311381403119757,0.3885005023995106,-0.24418159668346107,0.7862799512775219,2.311381403119757,0.6687795395939293,-0.740532149740219,0.7277194848631139,-0.2661038286652666,-0.1138401084971145,0.18272500423106916,0.8057169414204521,-0.37659150480827835,-1.2202811138168626,-0.0708373510934119,-0.31012230394858126,-1.7059780565784959,0.8057169414204521,0.05688083594047554,1.0736179845718188,0.12003241207649194,-1.3702552416869775,0.8444676370207627,-1.0248100286459398,2.092859600557418,0.09903334462182867,-0.48858049757519073,-0.5338093246549072,2.509065367944047,-1.785701460422968,0.20352212550695528,0.4896128041999829,0.6884687739263295,0.6687795395939293,0.3885005023995106,-0.5111634909229179,1.3156964634073816,0.26561689337391103,-0.15706295482882135,0.014520145426408674,-0.556518486029154,-0.37659150480827835,1.497816080363346,2.6065219729812474,0.4290838414759394,0.4896128041999829,0.30676947108334135,-0.24418159668346107,1.1861172256824857,-0.740532149740219,-0.09231141282339332,0.5096980023516975,-0.04941754059447337,0.9214825561524033,-1.5491193478204588,0.5696841825408305,-1.195572223965075,2.0758547589474974,-0.48858049757519073,6.587934544608236,-0.28808392260207233,-0.8577339369682366,0.32727353035340734,0.014520145426408674,4.959044238463191,2.956395767747345,0.34772985125492284,0.2449677445585254,2.557906632557138,-0.6250309026232277,-0.9767075535898113,-0.6941314197209414,-0.8577339369682366,-0.3543756565400391,0.4290838414759394,3.915034698124895,0.7472814698483077
| 3,210
|
Establishment of protein localization to membrane
| 15
| 89
| 3.014092
| 0.002577
|
Q9P0J0,Q9NS69,O60725,O43681,P63244,Q8N4V1,Q9H4A6,Q9Y584,Q15070,P09132,Q15629,P43307,P46379,Q9HD20,Q9NT62
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,6,40,104,138,168,232,13,45,177,22,86,214,28,61
|
1125,2546,2332,1414,848,610,493,423,104,531,40,1315,1785,587,1530,2416,1654,2308,177,2898,2023,1699,1356,1532,239,1879,86,214,2948,720,1103,2833,1385,880,3104,2924,1882,1794,2960,138,2732,1884,2193,1886,2259,2716,802,2284,45,22,1019,321,1989,1172,1235,3128,2969,834,427,168,2457,3080,837,2988,375,2363,1440,2620,1446,745,1678,232,1679,28,991,6,61,33,1310,1032,544,1729,649,2905,2789,1091,872,13,529
|
0.2449677445585254,-0.6479983733197957,-0.48858049757519073,0.05688083594047554,0.4290838414759394,0.64904737623524,0.7668015426370355,0.8637818220779606,1.9387760747315386,0.7277194848631139,2.8463083615822415,0.12003241207649194,-0.13542382527329797,0.6687795395939293,-0.006739164246572185,-0.5338093246549072,-0.0708373510934119,-0.46605986346971,1.4616665228240524,-1.0248100286459398,-0.2661038286652666,-0.09231141282339332,0.09903334462182867,-0.006739164246572185,1.2233207047385817,-0.1787578934323262,2.143704011138066,1.297292869739083,-1.121922556458858,0.5497334133991656,0.26561689337391103,-0.9289007210857031,0.07798293576717874,0.40881543685910227,-1.73245439296629,-1.0732132719357752,-0.1787578934323262,-0.13542382527329797,-1.146393653735946,1.6942735085784877,-0.8106447024352365,-0.1787578934323262,-0.37659150480827835,-0.1787578934323262,-0.42120377836259065,-0.7872049149016607,0.4694822353754309,-0.44360111347426245,2.6065219729812474,3.3407208935166444,0.32727353035340734,1.0547363295691754,-0.24418159668346107,0.22426959652252174,0.18272500423106916,-1.8934020128115538,-1.1709433084847787,0.44930601055840114,0.8637818220779606,1.5338312891339945,-0.556518486029154,-1.5491193478204588,0.44930601055840114,-1.195572223965075,0.9597505084681618,-0.48858049757519073,0.05688083594047554,-0.6941314197209414,0.05688083594047554,0.5297381122387874,-0.0708373510934119,1.2603787307732723,-0.0708373510934119,3.15792453539255,0.34772985125492284,4.959044238463191,2.3611563581788624,2.956395767747345,0.14098048384438178,0.32727353035340734,0.7277194848631139,-0.09231141282339332,0.6292720233130275,-1.0248100286459398,-0.8577339369682366,0.286217363258279,0.4290838414759394,3.915034698124895,0.7472814698483077
| 3,210
|
Protein localization to mitochondrion
| 10
| 58
| 2.976228
| 0.002918
|
Q99595,Q9P0J0,Q9NS69,O00170,Q10713,Q9Y584,Q15070,P52789,P30536,Q9Y6C9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,33,6,72,171,13,45,210,91,29
|
72,2332,1313,848,1255,3094,937,1977,587,2658,533,2017,1742,1222,1654,3100,2982,1493,1419,2898,91,357,1356,773,572,2384,210,1104,2447,2193,171,45,860,777,1047,1989,257,1714,402,3080,702,2988,0,2065,2782,1028,6,2863,33,993,1151,2542,2789,2172,872,13,529,29
|
2.2780642718897113,-0.48858049757519073,0.12003241207649194,0.4290838414759394,0.16187790183882575,-1.65331482085283,0.36813874070508046,-0.24418159668346107,0.6687795395939293,-0.740532149740219,0.7277194848631139,-0.2661038286652666,-0.1138401084971145,0.18272500423106916,-0.0708373510934119,-1.7059780565784959,-1.195572223965075,0.014520145426408674,0.05688083594047554,-1.0248100286459398,2.092859600557418,0.9788254062828049,0.09903334462182867,0.4896128041999829,0.6884687739263295,-0.5111634909229179,1.3156964634073816,0.26561689337391103,-0.556518486029154,-0.37659150480827835,1.497816080363346,2.6065219729812474,0.4290838414759394,0.4896128041999829,0.30676947108334135,-0.24418159668346107,1.1861172256824857,-0.09231141282339332,0.9214825561524033,-1.5491193478204588,0.5696841825408305,-1.195572223965075,6.587934544608236,-0.28808392260207233,-0.8577339369682366,0.32727353035340734,4.959044238463191,-0.9527674967759283,2.956395767747345,0.34772985125492284,0.2449677445585254,-0.6250309026232277,-0.8577339369682366,-0.3543756565400391,0.4290838414759394,3.915034698124895,0.7472814698483077,3.065374122452209
| 3,210
|
Protein targeting
| 17
| 111
| 2.969729
| 0.002981
|
Q99595,Q9P0J0,Q9NS69,O60725,O00170,O43681,Q10713,Q9Y584,P40855,P27695,P09132,Q15629,P43307,P46379,P30536,Q9NT62,Q9Y5M8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,33,6,40,72,104,171,13,239,246,177,22,86,214,91,61,261
|
1125,2546,72,2332,1414,1566,848,1255,1824,3094,937,104,531,2879,40,2595,1977,1785,587,2658,533,2017,1742,1222,1654,2308,177,3100,2629,1419,2214,1459,246,91,2023,1699,1838,1356,1532,239,86,214,1383,773,720,572,1103,2833,2384,1104,880,1659,3104,2446,1882,2960,1501,2115,2769,1012,2447,171,1886,2259,2935,1298,860,22,777,348,1047,1989,257,2900,3128,2950,1201,1714,2969,834,427,402,702,1405,1440,2364,2161,0,2065,1446,2782,1028,1644,6,61,33,993,1151,1310,1032,544,2542,707,649,815,2172,1091,872,13,529,261
|
0.2449677445585254,-0.6479983733197957,2.2780642718897113,-0.48858049757519073,0.05688083594047554,-0.028051602989249587,0.4290838414759394,0.16187790183882575,-0.15706295482882135,-1.65331482085283,0.36813874070508046,1.9387760747315386,0.7277194848631139,-1.0007215188288232,2.8463083615822415,-0.6941314197209414,-0.24418159668346107,-0.13542382527329797,0.6687795395939293,-0.740532149740219,0.7277194848631139,-0.2661038286652666,-0.1138401084971145,0.18272500423106916,-0.0708373510934119,-0.46605986346971,1.4616665228240524,-1.7059780565784959,-0.7172980550040869,0.05688083594047554,-0.3988673947128502,0.03572669165067375,1.204737245801071,2.092859600557418,-0.2661038286652666,-0.09231141282339332,-0.15706295482882135,0.09903334462182867,-0.006739164246572185,1.2233207047385817,2.143704011138066,1.297292869739083,0.07798293576717874,0.4896128041999829,0.5497334133991656,0.6884687739263295,0.26561689337391103,-0.9289007210857031,-0.5111634909229179,0.26561689337391103,0.40881543685910227,-0.0708373510934119,-1.73245439296629,-0.556518486029154,-0.1787578934323262,-1.146393653735946,0.014520145426408674,-0.332219403312167,-0.8577339369682366,0.32727353035340734,-0.556518486029154,1.497816080363346,-0.1787578934323262,-0.42120377836259065,-1.0975293235654124,0.14098048384438178,0.4290838414759394,3.3407208935166444,0.4896128041999829,0.9978612170400448,0.30676947108334135,-0.24418159668346107,1.1861172256824857,-1.0248100286459398,-1.8934020128115538,-1.121922556458858,0.20352212550695528,-0.09231141282339332,-1.1709433084847787,0.44930601055840114,0.8637818220779606,0.9214825561524033,0.5696841825408305,0.07798293576717874,0.05688083594047554,-0.48858049757519073,-0.3543756565400391,6.587934544608236,-0.28808392260207233,0.05688083594047554,-0.8577339369682366,0.32727353035340734,-0.04941754059447337,4.959044238463191,2.3611563581788624,2.956395767747345,0.34772985125492284,0.2449677445585254,0.14098048384438178,0.32727353035340734,0.7277194848631139,-0.6250309026232277,0.5696841825408305,0.6292720233130275,0.4694822353754309,-0.3543756565400391,0.286217363258279,0.4290838414759394,3.915034698124895,0.7472814698483077,1.1861172256824857
| 3,210
|
Organic acid transmembrane transport
| 7
| 28
| 2.940882
| 0.003273
|
Q9H2D1,O43772,P33527,P53985,Q9UBX3,P08183,Q9Y619
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,66,267,145,50,113,59
|
2108,66,478,2050,2627,2553,113,2080,312,1422,2083,1699,1136,267,1700,912,2445,145,775,526,1937,1,1772,1941,1969,50,2877,59
|
-0.332219403312167,2.311381403119757,0.7862799512775219,-0.28808392260207233,-0.7172980550040869,-0.6479983733197957,1.8521420832959734,-0.31012230394858126,1.0736179845718188,0.05688083594047554,-0.31012230394858126,-0.09231141282339332,0.2449677445585254,1.1674604442373642,-0.09231141282339332,0.3885005023995106,-0.556518486029154,1.6588461750842975,0.4896128041999829,0.7472814698483077,-0.20050904201939973,5.424065052068769,-0.1138401084971145,-0.20050904201939973,-0.22231680626932795,2.557906632557138,-0.9767075535898113,2.4435871616487934
| 3,210
|
Cardiac muscle contraction
| 11
| 22
| 2.90546
| 0.003667
|
P31930,P14406,P14854,Q9UDW1,O14949,P09493,P16615,P20674,P13073,P00403,P06753
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
220,5,229,75,76,549,397,498,370,334,283
|
76,334,734,2416,283,823,549,2685,1873,370,5,229,875,1289,397,498,569,220,2383,1358,1014,75
|
2.2446389541407687,1.016858162020565,0.5297381122387874,-0.5338093246549072,1.1300357877506997,0.44930601055840114,0.7081153372030551,-0.7638342514312623,-0.1787578934323262,0.9597505084681618,4.972198060062475,1.2603787307732723,0.40881543685910227,0.14098048384438178,0.9214825561524033,0.7668015426370355,0.6884687739263295,1.278853689347875,-0.5111634909229179,0.09903334462182867,0.32727353035340734,2.2613651972231907
| 3,210
|
Ventricular hypertrophy
| 14
| 40
| 2.896237
| 0.003777
|
O43772,P00403,P14854,Q15233,O00170,P40939,O75844,P23786,Q96MF7,P12235,P03886,P78536,P46976,P31040
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,334,229,485,72,170,20,312,183,467,152,248,313,435
|
72,66,903,495,20,1097,1453,334,2881,152,2764,1695,2442,467,1418,229,1317,2341,312,435,751,2571,968,170,1041,313,2481,248,1985,620,1928,485,2671,2286,1804,839,183,1114,1446,1305
|
2.2780642718897113,2.311381403119757,0.3885005023995106,0.7668015426370355,3.535416449055476,0.26561689337391103,0.03572669165067375,1.016858162020565,-1.0007215188288232,1.6232905049437316,-0.8577339369682366,-0.09231141282339332,-0.556518486029154,0.8057169414204521,0.05688083594047554,1.2603787307732723,0.12003241207649194,-0.48858049757519073,1.0736179845718188,0.8444676370207627,0.5096980023516975,-0.6710317035777431,0.34772985125492284,1.515840391838553,0.30676947108334135,1.0736179845718188,-0.5792914685282397,1.204737245801071,-0.24418159668346107,0.64904737623524,-0.20050904201939973,0.7862799512775219,-0.740532149740219,-0.44360111347426245,-0.13542382527329797,0.44930601055840114,1.443540927049774,0.26561689337391103,0.05688083594047554,0.14098048384438178
| 3,210
|
Electron transfer activity
| 19
| 51
| 2.892903
| 0.003817
|
Q9Y6M9,P14406,P16435,P03886,O95298,Q9P0J0,O43676,P31040,O43175,P51970,Q9UDW1,P00403,O75306,P31930,P14854,O15121,P20674,P13073,P15121
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
530,5,153,152,282,33,41,435,190,573,75,334,464,220,229,108,498,370,371
|
996,2657,108,190,1485,41,1155,1281,1416,464,711,1487,282,690,655,334,152,2706,823,1873,1491,370,2309,5,229,371,153,2603,498,1317,2932,2252,3117,3019,435,220,2947,2383,1426,573,2691,2320,977,1542,2887,2500,595,1237,33,75,530
|
0.32727353035340734,-0.740532149740219,1.8868858346923807,1.4071872159758687,0.014520145426408674,2.814646690863611,0.22426959652252174,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,1.1300357877506997,0.5696841825408305,0.6094532176877998,1.016858162020565,1.6232905049437316,-0.7872049149016607,0.44930601055840114,-0.1787578934323262,0.014520145426408674,0.9597505084681618,-0.46605986346971,4.972198060062475,1.2603787307732723,0.9597505084681618,1.6232905049437316,-0.6941314197209414,0.7668015426370355,0.12003241207649194,-1.0975293235654124,-0.42120377836259065,-1.8124742250552148,-1.2948949262443985,0.8444676370207627,1.278853689347875,-1.121922556458858,-0.5111634909229179,0.05688083594047554,0.6884687739263295,-0.7638342514312623,-0.46605986346971,0.34772985125492284,-0.006739164246572185,-1.0007215188288232,-0.6021287719704128,0.6687795395939293,0.18272500423106916,2.956395767747345,2.2613651972231907,0.7472814698483077
| 3,210
|
Membrane lipid biosynthetic process
| 9
| 22
| 2.886418
| 0.003897
|
O95470,P27544,Q96G23,Q16739,P04062,O15121,Q13510,Q8NBX0,Q06136
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
35,296,172,44,325,108,304,318,155
|
108,611,1825,1280,2812,35,325,944,296,155,304,44,1989,318,2674,172,2292,1677,1646,377,2678,606
|
1.8868858346923807,0.64904737623524,-0.15706295482882135,0.14098048384438178,-0.9051066078988986,2.9093530775549494,1.0358164604588085,0.36813874070508046,1.1112675033149844,1.6054641390302427,1.092461638717988,2.6709959483183634,-0.24418159668346107,1.0736179845718188,-0.740532149740219,1.497816080363346,-0.44360111347426245,-0.0708373510934119,-0.04941754059447337,0.9597505084681618,-0.740532149740219,0.6687795395939293
| 3,210
|
Transporter activity
| 54
| 171
| 2.866392
| 0.004152
|
Q9Y5J9,Q99595,Q9H2D1,Q9NS69,Q9BSK2,Q9Y584,P33527,P53985,P21796,P16615,Q14847,P03886,O00299,O95298,Q9HD20,Q99808,Q9P0J0,Q8TB61,Q8N4V1,O43676,O00400,Q9UBX3,Q6P4A7,P45880,Q8WTV0,Q70HW3,Q9Y619,O43772,O75964,Q93050,Q9UDW1,P04062,P38435,Q7L0J3,P00403,O75027,P12235,P30536,O75306,P31930,P23634,P14854,O43681,O75947,Q8N1S5,Q9Y277,P08183,Q8IUH4,P20674,P13073,O15173,O15118,Q96NB2,Q96AA3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
529,0,1,6,9,13,267,145,19,397,279,152,275,282,28,156,33,163,168,41,43,50,440,52,181,55,59,66,67,459,75,325,207,84,334,333,467,91,464,220,219,229,104,479,112,506,113,374,498,370,120,493,526,524
|
652,996,275,43,2657,2108,565,1255,493,120,1867,41,104,66,2134,1281,333,1416,464,711,1487,2050,479,67,587,2016,282,690,1222,334,152,325,734,2416,2180,2993,2212,2274,113,2080,823,3142,1873,467,2686,370,229,397,1005,2603,1875,498,2339,3160,19,944,219,1318,3037,1422,3117,91,2083,220,267,1700,2343,2571,207,2084,52,2383,3113,1263,1322,1426,3048,573,722,1983,2445,145,1658,1841,1500,2691,1622,2960,1042,2732,2449,887,775,1108,2087,2193,2608,1504,2772,2395,801,279,860,2887,2500,1048,3184,2671,1200,440,55,1237,84,1112,374,3147,112,168,837,2458,1330,163,181,2357,2360,459,524,526,811,2916,893,0,2065,156,2240,1937,9,3031,1057,3106,2564,1251,2902,1,1772,3070,1941,1969,560,746,28,1524,6,2919,33,50,75,1310,1563,2877,2169,1687,506,731,13,529,1527,59,1688,2760,530
|
0.6094532176877998,0.32727353035340734,1.1487666995177788,2.687053265961324,-0.740532149740219,-0.332219403312167,0.6884687739263295,0.16187790183882575,0.7668015426370355,1.7997981488475483,-0.1787578934323262,2.814646690863611,1.9387760747315386,2.311381403119757,-0.3543756565400391,0.14098048384438178,1.016858162020565,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,-0.28808392260207233,0.7862799512775219,2.311381403119757,0.6687795395939293,-0.2661038286652666,1.1300357877506997,0.5696841825408305,0.18272500423106916,1.016858162020565,1.6232905049437316,1.0358164604588085,0.5297381122387874,-0.5338093246549072,-0.37659150480827835,-1.2202811138168626,-0.3988673947128502,-0.44360111347426245,1.8521420832959734,-0.31012230394858126,0.44930601055840114,-2.030379226705189,-0.1787578934323262,0.8057169414204521,-0.7638342514312623,0.9597505084681618,1.2603787307732723,0.9214825561524033,0.32727353035340734,-0.6941314197209414,-0.1787578934323262,0.7668015426370355,-0.48858049757519073,-2.2268000244687314,3.565072073980479,0.36813874070508046,1.278853689347875,0.12003241207649194,-1.3702552416869775,0.05688083594047554,-1.8124742250552148,2.092859600557418,-0.31012230394858126,1.278853689347875,1.1674604442373642,-0.09231141282339332,-0.48858049757519073,-0.6710317035777431,1.3340646601393549,-0.31012230394858126,2.509065367944047,-0.5111634909229179,-1.785701460422968,0.16187790183882575,0.12003241207649194,0.05688083594047554,-1.42092054737106,0.6884687739263295,0.5497334133991656,-0.24418159668346107,-0.556518486029154,1.6588461750842975,-0.0708373510934119,-0.15706295482882135,0.014520145426408674,-0.7638342514312623,-0.04941754059447337,-1.146393653735946,0.30676947108334135,-0.8106447024352365,-0.556518486029154,0.40881543685910227,0.4896128041999829,0.26561689337391103,-0.31012230394858126,-0.37659150480827835,-0.6941314197209414,0.014520145426408674,-0.8577339369682366,-0.5111634909229179,0.4694822353754309,1.1487666995177788,0.4290838414759394,-1.0007215188288232,-0.6021287719704128,0.30676947108334135,-2.7908471566158775,-0.740532149740219,0.20352212550695528,0.8444676370207627,2.4599952437757544,0.18272500423106916,2.160595878265183,0.26561689337391103,0.9597505084681618,-2.085931168920067,1.8695290813707817,1.5338312891339945,0.44930601055840114,-0.556518486029154,0.12003241207649194,1.5517889434452048,1.4616665228240524,-0.48858049757519073,-0.48858049757519073,0.8251127563510817,0.7472814698483077,0.7472814698483077,0.4694822353754309,-1.0489737282202127,0.40881543685910227,6.587934544608236,-0.28808392260207233,1.6054641390302427,-0.3988673947128502,-0.20050904201939973,4.268651553761713,-1.3199310652066065,0.30676947108334135,-1.73245439296629,-0.6479983733197957,0.18272500423106916,-1.0248100286459398,5.424065052068769,-0.1138401084971145,-1.4975723754350228,-0.20050904201939973,-0.22231680626932795,0.7081153372030551,0.5297381122387874,3.15792453539255,0.014520145426408674,4.959044238463191,-1.0489737282202127,2.956395767747345,2.557906632557138,2.2613651972231907,0.14098048384438178,-0.006739164246572185,-0.9767075535898113,-0.3543756565400391,-0.0708373510934119,0.7668015426370355,0.5497334133991656,3.915034698124895,0.7472814698483077,0.014520145426408674,2.4435871616487934,-0.0708373510934119,-0.8341541839153083,0.7472814698483077
| 3,210
|
Protein targeting to mitochondrion
| 7
| 44
| 2.863881
| 0.004185
|
Q99595,Q9P0J0,Q9NS69,O00170,Q10713,Q9Y584,P30536
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,33,6,72,171,13,91
|
72,848,1255,3094,937,1977,587,2658,533,2017,1742,1222,1654,3100,1419,91,1356,773,572,2384,1104,2447,171,860,777,1047,1989,257,1714,402,702,0,2065,2782,1028,6,33,993,1151,2542,2172,872,13,529
|
2.2780642718897113,0.4290838414759394,0.16187790183882575,-1.65331482085283,0.36813874070508046,-0.24418159668346107,0.6687795395939293,-0.740532149740219,0.7277194848631139,-0.2661038286652666,-0.1138401084971145,0.18272500423106916,-0.0708373510934119,-1.7059780565784959,0.05688083594047554,2.092859600557418,0.09903334462182867,0.4896128041999829,0.6884687739263295,-0.5111634909229179,0.26561689337391103,-0.556518486029154,1.497816080363346,0.4290838414759394,0.4896128041999829,0.30676947108334135,-0.24418159668346107,1.1861172256824857,-0.09231141282339332,0.9214825561524033,0.5696841825408305,6.587934544608236,-0.28808392260207233,-0.8577339369682366,0.32727353035340734,4.959044238463191,2.956395767747345,0.34772985125492284,0.2449677445585254,-0.6250309026232277,-0.3543756565400391,0.4290838414759394,3.915034698124895,0.7472814698483077
| 3,210
|
Metapathway biotransformation phase i and ii
| 10
| 21
| 2.825952
| 0.004714
|
Q99735,P21266,P14550,P15121,Q16850,P21964,Q8NCH0,Q6UW02,Q86UY6,P07099
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
386,327,451,371,140,301,118,316,317,27
|
1485,2473,655,27,851,451,371,327,301,1421,2345,799,140,316,1176,317,118,386,475,2434,2469
|
0.014520145426408674,-0.5792914685282397,0.6094532176877998,3.1732738631171533,0.4290838414759394,0.8251127563510817,0.9597505084681618,1.0358164604588085,1.092461638717988,0.05688083594047554,-0.48858049757519073,0.4694822353754309,1.6765758036559943,1.0736179845718188,0.22426959652252174,1.0736179845718188,1.8172767653783097,0.9406363002425452,0.8057169414204521,-0.5338093246549072,-0.556518486029154
| 3,210
|
Slc mediated transmembrane transport
| 6
| 20
| 2.822544
| 0.004764
|
Q8TB61,O00400,P53985,Q9UBX3,Q70HW3,Q99808
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
163,43,145,50,55,156
|
43,2180,2080,467,2686,792,2083,191,2660,145,1658,1200,55,163,2357,156,1772,1941,50,2760
|
2.687053265961324,-0.37659150480827835,-0.31012230394858126,0.8057169414204521,-0.7638342514312623,0.4694822353754309,-0.31012230394858126,1.4071872159758687,-0.740532149740219,1.6588461750842975,-0.0708373510934119,0.20352212550695528,2.4599952437757544,1.5517889434452048,-0.48858049757519073,1.6054641390302427,-0.1138401084971145,-0.20050904201939973,2.557906632557138,-0.8341541839153083
| 3,210
|
Sphingolipid metabolism in senescence
| 6
| 12
| 2.819733
| 0.004806
|
O15121,Q96G23,Q16739,P11802,Q13510,Q06136
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
108,172,44,144,304,155
|
108,611,325,144,1492,1069,635,1702,155,304,44,172
|
1.8868858346923807,0.64904737623524,1.0358164604588085,1.6588461750842975,0.014520145426408674,0.286217363258279,0.6292720233130275,-0.09231141282339332,1.6054641390302427,1.092461638717988,2.6709959483183634,1.497816080363346
| 3,210
|
Anion transmembrane transporter activity
| 11
| 42
| 2.817412
| 0.004841
|
Q9H2D1,Q8TB61,O43681,O00400,P33527,P53985,Q9UBX3,P21796,P45880,Q9Y619,Q99808
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
1,163,104,43,267,145,50,19,52,59,156
|
275,43,565,1867,104,2134,2050,2180,2080,3142,467,2686,19,2083,267,52,3048,2445,145,1658,775,801,1048,3184,2671,1200,163,526,811,156,1937,1251,1,1941,1969,746,50,2877,506,59,1688,2760
|
1.1487666995177788,2.687053265961324,0.6884687739263295,-0.1787578934323262,1.9387760747315386,-0.3543756565400391,-0.28808392260207233,-0.37659150480827835,-0.31012230394858126,-2.030379226705189,0.8057169414204521,-0.7638342514312623,3.565072073980479,-0.31012230394858126,1.1674604442373642,2.509065367944047,-1.42092054737106,-0.556518486029154,1.6588461750842975,-0.0708373510934119,0.4896128041999829,0.4694822353754309,0.30676947108334135,-2.7908471566158775,-0.740532149740219,0.20352212550695528,1.5517889434452048,0.7472814698483077,0.4694822353754309,1.6054641390302427,-0.20050904201939973,0.18272500423106916,5.424065052068769,-0.20050904201939973,-0.22231680626932795,0.5297381122387874,2.557906632557138,-0.9767075535898113,0.7668015426370355,2.4435871616487934,-0.0708373510934119,-0.8341541839153083
| 3,210
|
Oxidative phosphorylation
| 19
| 58
| 2.736582
| 0.006208
|
Q9Y6M9,P14406,Q9BSK2,P03886,O95298,O43676,P31040,P30405,P51970,P61586,O75964,Q9UDW1,O14949,P00403,O75306,P31930,O75947,P20674,P13073
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
530,5,9,152,282,41,435,434,573,193,67,75,76,334,464,220,479,498,370
|
996,2657,76,41,1281,1416,464,711,1487,479,67,282,690,334,152,632,2993,823,2602,1873,370,5,1131,875,1289,2603,498,569,1318,3037,3117,434,435,220,1700,2279,2343,1321,2383,3113,1426,573,1881,1841,1500,2691,193,2887,2500,1667,1237,2675,9,1814,869,75,2624,530
|
0.32727353035340734,-0.740532149740219,2.2446389541407687,2.814646690863611,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,0.7862799512775219,2.311381403119757,1.1300357877506997,0.5696841825408305,1.016858162020565,1.6232905049437316,0.6292720233130275,-1.2202811138168626,0.44930601055840114,-0.6941314197209414,-0.1787578934323262,0.9597505084681618,4.972198060062475,0.2449677445585254,0.40881543685910227,0.14098048384438178,-0.6941314197209414,0.7668015426370355,0.6884687739263295,0.12003241207649194,-1.3702552416869775,-1.8124742250552148,0.8444676370207627,0.8444676370207627,1.278853689347875,-0.09231141282339332,-0.44360111347426245,-0.48858049757519073,0.12003241207649194,-0.5111634909229179,-1.785701460422968,0.05688083594047554,0.6884687739263295,-0.1787578934323262,-0.15706295482882135,0.014520145426408674,-0.7638342514312623,1.4071872159758687,-1.0007215188288232,-0.6021287719704128,-0.0708373510934119,0.18272500423106916,-0.740532149740219,4.268651553761713,-0.13542382527329797,0.4290838414759394,2.2613651972231907,-0.6941314197209414,0.7472814698483077
| 3,210
|
Organic anion transport
| 20
| 44
| 2.735505
| 0.006228
|
Q9H2D1,Q02978,P33527,P53985,Q99808,Q9NZJ7,Q14728,Q8TB61,O00400,Q9UBX3,Q9Y619,P04083,O14745,Q7L0J3,P07602,P12235,Q9HC21,P14174,O60831,Q96NB2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,775,267,145,156,686,801,163,43,50,59,568,565,84,335,467,746,735,478,526
|
43,565,1867,2134,478,2050,2627,568,2180,2553,335,2080,851,467,2686,735,2019,1422,2083,267,2445,145,1658,775,801,2284,2671,1200,84,163,526,156,1937,1,1772,1941,1969,746,844,686,50,2877,59,2760
|
2.687053265961324,0.6884687739263295,-0.1787578934323262,-0.3543756565400391,0.7862799512775219,-0.28808392260207233,-0.7172980550040869,0.6884687739263295,-0.37659150480827835,-0.6479983733197957,1.016858162020565,-0.31012230394858126,0.4290838414759394,0.8057169414204521,-0.7638342514312623,0.5297381122387874,-0.2661038286652666,0.05688083594047554,-0.31012230394858126,1.1674604442373642,-0.556518486029154,1.6588461750842975,-0.0708373510934119,0.4896128041999829,0.4694822353754309,-0.44360111347426245,-0.740532149740219,0.20352212550695528,2.160595878265183,1.5517889434452048,0.7472814698483077,1.6054641390302427,-0.20050904201939973,5.424065052068769,-0.1138401084971145,-0.20050904201939973,-0.22231680626932795,0.5297381122387874,0.44930601055840114,0.5895906935815504,2.557906632557138,-0.9767075535898113,2.4435871616487934,-0.8341541839153083
| 3,210
|
Sphingolipid metabolism integrated pathway
| 6
| 9
| 2.715031
| 0.006627
|
O95470,P27544,Q96G23,O15121,Q16739,Q06136
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
35,296,172,108,44,155
|
108,611,1825,35,296,155,304,44,172
|
1.8868858346923807,0.64904737623524,-0.15706295482882135,2.9093530775549494,1.1112675033149844,1.6054641390302427,1.092461638717988,2.6709959483183634,1.497816080363346
| 3,210
|
Sphingolipid metabolism overview
| 6
| 9
| 2.715031
| 0.006627
|
O95470,P27544,Q96G23,O15121,Q16739,Q06136
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
35,296,172,108,44,155
|
108,611,1825,35,296,155,304,44,172
|
1.8868858346923807,0.64904737623524,-0.15706295482882135,2.9093530775549494,1.1112675033149844,1.6054641390302427,1.092461638717988,2.6709959483183634,1.497816080363346
| 3,210
|
Organic anion transmembrane transporter activity
| 7
| 29
| 2.691468
| 0.007114
|
Q9H2D1,Q8TB61,O00400,P53985,Q9UBX3,Q9Y619,Q99808
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
1,163,43,145,50,59,156
|
43,565,1867,2134,2050,2180,2080,467,2686,2083,267,2445,145,775,801,2671,1200,163,526,156,1937,1,1941,1969,746,50,2877,59,2760
|
2.687053265961324,0.6884687739263295,-0.1787578934323262,-0.3543756565400391,-0.28808392260207233,-0.37659150480827835,-0.31012230394858126,0.8057169414204521,-0.7638342514312623,-0.31012230394858126,1.1674604442373642,-0.556518486029154,1.6588461750842975,0.4896128041999829,0.4694822353754309,-0.740532149740219,0.20352212550695528,1.5517889434452048,0.7472814698483077,1.6054641390302427,-0.20050904201939973,5.424065052068769,-0.20050904201939973,-0.22231680626932795,0.5297381122387874,2.557906632557138,-0.9767075535898113,2.4435871616487934,-0.8341541839153083
| 3,210
|
Active transmembrane transporter activity
| 21
| 73
| 2.667577
| 0.00764
|
P33527,P53985,P16615,P03886,O95298,Q9HD20,Q9P0J0,O43676,O00400,Q9UBX3,Q9UDW1,P00403,O75027,P12235,O75306,P31930,P23634,P14854,P08183,P20674,P13073
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
267,145,397,152,282,28,33,41,43,50,75,334,333,467,464,220,219,229,113,498,370
|
996,43,2657,2108,1867,41,1281,333,1416,464,711,1487,2016,282,690,334,152,734,2416,2180,2993,113,2080,823,1873,467,2686,370,229,397,2603,1875,498,2339,3160,219,1422,3117,220,267,1700,2571,2084,2383,1426,3048,573,2445,145,1658,2691,1622,2732,887,775,1108,2087,860,2887,2500,1237,1330,1772,1941,28,1524,33,50,75,1563,1527,2760,530
|
0.32727353035340734,2.687053265961324,-0.740532149740219,-0.332219403312167,-0.1787578934323262,2.814646690863611,0.14098048384438178,1.016858162020565,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,-0.2661038286652666,1.1300357877506997,0.5696841825408305,1.016858162020565,1.6232905049437316,0.5297381122387874,-0.5338093246549072,-0.37659150480827835,-1.2202811138168626,1.8521420832959734,-0.31012230394858126,0.44930601055840114,-0.1787578934323262,0.8057169414204521,-0.7638342514312623,0.9597505084681618,1.2603787307732723,0.9214825561524033,-0.6941314197209414,-0.1787578934323262,0.7668015426370355,-0.48858049757519073,-2.2268000244687314,1.278853689347875,0.05688083594047554,-1.8124742250552148,1.278853689347875,1.1674604442373642,-0.09231141282339332,-0.6710317035777431,-0.31012230394858126,-0.5111634909229179,0.05688083594047554,-1.42092054737106,0.6884687739263295,-0.556518486029154,1.6588461750842975,-0.0708373510934119,-0.7638342514312623,-0.04941754059447337,-0.8106447024352365,0.40881543685910227,0.4896128041999829,0.26561689337391103,-0.31012230394858126,0.4290838414759394,-1.0007215188288232,-0.6021287719704128,0.18272500423106916,0.12003241207649194,-0.1138401084971145,-0.20050904201939973,3.15792453539255,0.014520145426408674,2.956395767747345,2.557906632557138,2.2613651972231907,-0.006739164246572185,0.014520145426408674,-0.8341541839153083,0.7472814698483077
| 3,210
|
Parkinsons disease
| 21
| 55
| 2.66402
| 0.007721
|
Q9Y6M9,P14406,P21796,P03886,O95298,O43676,P45880,P31040,P51970,Q9UDW1,O14949,P00403,P12235,O75306,P31930,P14854,O75947,Q9Y277,Q08752,P13073,P20674
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
530,5,19,152,282,41,52,435,573,75,76,334,467,464,220,229,479,506,372,370,498
|
996,2657,76,3094,41,1281,1416,464,711,1487,479,282,690,334,152,2180,2993,823,2685,1873,467,2686,370,5,229,875,1289,2603,498,19,1317,1351,569,1318,3037,3117,435,220,2343,717,52,2383,3113,1426,573,2691,1105,2447,372,2887,2500,2675,75,506,530
|
0.32727353035340734,-0.740532149740219,2.2446389541407687,-1.65331482085283,2.814646690863611,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,0.7862799512775219,1.1300357877506997,0.5696841825408305,1.016858162020565,1.6232905049437316,-0.37659150480827835,-1.2202811138168626,0.44930601055840114,-0.7638342514312623,-0.1787578934323262,0.8057169414204521,-0.7638342514312623,0.9597505084681618,4.972198060062475,1.2603787307732723,0.40881543685910227,0.14098048384438178,-0.6941314197209414,0.7668015426370355,3.565072073980479,0.12003241207649194,0.09903334462182867,0.6884687739263295,0.12003241207649194,-1.3702552416869775,-1.8124742250552148,0.8444676370207627,1.278853689347875,-0.48858049757519073,0.5497334133991656,2.509065367944047,-0.5111634909229179,-1.785701460422968,0.05688083594047554,0.6884687739263295,-0.7638342514312623,0.26561689337391103,-0.556518486029154,0.9597505084681618,-1.0007215188288232,-0.6021287719704128,-0.740532149740219,2.2613651972231907,0.7668015426370355,0.7472814698483077
| 3,210
|
Sphingolipid pathway
| 6
| 9
| 2.662952
| 0.007746
|
O95470,P62136,Q96G23,Q16739,Q13510,Q06136
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
35,204,172,44,304,155
|
611,1825,35,325,204,155,304,44,172
|
0.64904737623524,-0.15706295482882135,2.9093530775549494,1.0358164604588085,1.352397648067967,1.6054641390302427,1.092461638717988,2.6709959483183634,1.497816080363346
| 3,210
|
Endoplasmic reticulum golgi intermediate compartment
| 10
| 52
| 2.66029
| 0.007807
|
O15498,Q02818,Q8N511,Q9Y282,P09429,P80303,P24390,O15260,P30533,Q10472
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
218,63,3,332,234,12,16,56,247,216
|
654,56,218,2829,2078,1002,326,234,16,2417,2922,247,773,1322,1498,2384,2057,2027,1386,12,63,1108,2087,2925,216,1465,888,1844,1506,3079,2926,1019,1850,2488,1365,3,2649,2973,1403,579,986,2756,962,2102,2903,2591,544,332,2375,477,1376,1093
|
0.6094532176877998,2.4435871616487934,1.278853689347875,-0.9289007210857031,-0.31012230394858126,0.32727353035340734,1.0358164604588085,1.2418678008603015,3.7995660768900676,-0.5338093246549072,-1.0732132719357752,1.204737245801071,0.4896128041999829,0.12003241207649194,0.014520145426408674,-0.5111634909229179,-0.28808392260207233,-0.2661038286652666,0.07798293576717874,4.071945485745097,2.3279997010255387,0.26561689337391103,-0.31012230394858126,-1.0732132719357752,1.297292869739083,0.03572669165067375,0.40881543685910227,-0.15706295482882135,0.014520145426408674,-1.5491193478204588,-1.0732132719357752,0.32727353035340734,-0.15706295482882135,-0.5792914685282397,0.09903334462182867,5.180787262938392,-0.7172980550040869,-1.1709433084847787,0.07798293576717874,0.6884687739263295,0.34772985125492284,-0.8341541839153083,0.36813874070508046,-0.31012230394858126,-1.0248100286459398,-0.6710317035777431,0.7277194848631139,1.0358164604588085,-0.48858049757519073,0.8057169414204521,0.09903334462182867,0.286217363258279
| 3,210
|
oxidase
| 6
| 15
| 2.639089
| 0.008313
|
P14854,P14406,O75845,P36551,Q15800,P13073
|
Functions
|
Panther Protein class
|
panther_protein_class
|
229,5,293,382,54,370
|
2177,1187,293,1097,1873,370,5,229,1289,498,382,1357,54,2779,1242
|
-0.37659150480827835,0.20352212550695528,1.1112675033149844,0.26561689337391103,-0.1787578934323262,0.9597505084681618,4.972198060062475,1.2603787307732723,0.14098048384438178,0.7668015426370355,0.9406363002425452,0.09903334462182867,2.4927342354820032,-0.8577339369682366,0.18272500423106916
| 3,210
|
Spinal cord injury
| 11
| 17
| 2.62893
| 0.008565
|
P60953,P61586,P06493,P04083,P28482,P63000,P11802,Q9NQC3,P04637,P42574,P27695
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
574,193,632,568,635,636,144,82,466,717,246
|
2250,568,466,632,1576,144,735,1069,2056,246,635,717,574,193,2256,636,82
|
-0.42120377836259065,0.6884687739263295,0.8057169414204521,0.6292720233130275,-0.028051602989249587,1.6588461750842975,0.5297381122387874,0.286217363258279,-0.28808392260207233,1.204737245801071,0.6292720233130275,0.5497334133991656,0.6884687739263295,1.4071872159758687,-0.42120377836259065,0.6292720233130275,2.1942959806671287
| 3,210
|
Rhythmic process
| 18
| 59
| 2.613482
| 0.008962
|
Q00839,P42575,Q14103,O75592,P43490,O95470,P04083,Q15233,P63244,Q9BWF3,P62136,O95352,O75376,Q06210,Q13185,P04637,P49841,P04818
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
286,285,418,630,4,35,568,485,138,142,204,354,353,173,398,466,592,185
|
1313,819,1186,353,630,2250,354,35,568,466,185,632,2477,2497,1288,1004,1132,769,3018,1702,717,285,4,592,2636,204,1956,138,1708,286,2530,2817,173,2351,755,398,1888,1434,418,485,1396,2500,1714,1113,1805,1476,2289,1549,1209,1935,2508,2844,1178,142,1773,1122,1152,2171,1124
|
0.12003241207649194,0.44930601055840114,0.20352212550695528,0.9788254062828049,0.6292720233130275,-0.42120377836259065,0.9788254062828049,2.9093530775549494,0.6884687739263295,0.8057169414204521,1.4253812176403144,0.6292720233130275,-0.5792914685282397,-0.6021287719704128,0.14098048384438178,0.32727353035340734,0.2449677445585254,0.4896128041999829,-1.2948949262443985,-0.09231141282339332,0.5497334133991656,1.1300357877506997,5.037758494615925,0.6687795395939293,-0.7172980550040869,1.352397648067967,-0.22231680626932795,1.6942735085784877,-0.09231141282339332,1.1300357877506997,-0.6250309026232277,-0.9051066078988986,1.4797581820627799,-0.48858049757519073,0.5096980023516975,0.9214825561524033,-0.1787578934323262,0.05688083594047554,0.8830555478987258,0.7862799512775219,0.07798293576717874,-0.6021287719704128,-0.09231141282339332,0.26561689337391103,-0.13542382527329797,0.03572669165067375,-0.44360111347426245,-0.006739164246572185,0.20352212550695528,-0.20050904201939973,-0.6021287719704128,-0.9289007210857031,0.22426959652252174,1.6765758036559943,-0.1138401084971145,0.26561689337391103,0.2449677445585254,-0.3543756565400391,0.26561689337391103
| 3,210
|
Electron transport
| 24
| 47
| 2.607584
| 0.009118
|
Q9Y6M9,Q9H3N1,P03886,O95298,Q9P0J0,P35754,O43676,Q86Y39,Q6DKK2,P31040,P51970,O95299,P22695,O95864,Q9UDW1,O43169,O14949,O75380,P00403,O75306,P31930,Q9H1E5,Q96CU9,Q16881
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
530,135,152,282,33,793,41,174,439,435,573,690,569,822,75,74,76,711,334,464,220,231,762,778
|
996,2657,76,74,2792,41,1281,1416,464,711,1487,282,690,822,334,152,823,2309,875,2603,1317,1786,569,3117,435,220,793,2947,2383,1426,573,2691,1542,2887,2500,778,439,174,762,2809,1248,231,135,33,75,1647,530
|
0.32727353035340734,-0.740532149740219,2.2446389541407687,2.2613651972231907,-0.8813845471104144,2.814646690863611,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,1.1300357877506997,0.5696841825408305,0.44930601055840114,1.016858162020565,1.6232905049437316,0.44930601055840114,-0.46605986346971,0.40881543685910227,-0.6941314197209414,0.12003241207649194,-0.13542382527329797,0.6884687739263295,-1.8124742250552148,0.8444676370207627,1.278853689347875,0.4694822353754309,-1.121922556458858,-0.5111634909229179,0.05688083594047554,0.6884687739263295,-0.7638342514312623,-0.006739164246572185,-1.0007215188288232,-0.6021287719704128,0.4896128041999829,0.8444676370207627,1.4797581820627799,0.5096980023516975,-0.8813845471104144,0.18272500423106916,1.2603787307732723,1.7119394487268482,2.956395767747345,2.2613651972231907,-0.04941754059447337,0.7472814698483077
| 3,210
|
Cation transmembrane transporter activity
| 21
| 70
| 2.579109
| 0.009906
|
P16615,Q9HD20,Q99808,Q8N4V1,O00400,Q70HW3,Q9Y619,Q93050,O43772,O75964,Q9UDW1,P00403,P12235,P31930,P23634,P14854,O75947,Q8N1S5,Q8IUH4,P20674,P13073
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
397,28,156,168,43,55,59,459,66,67,75,334,467,220,219,229,479,112,374,498,370
|
43,66,2134,479,67,2016,334,734,2416,2180,2993,2212,2274,2080,823,1873,467,370,229,397,1875,498,2339,3160,219,1318,3037,2083,220,2343,2571,2084,2383,3113,3048,1658,1841,1500,1622,2960,2732,887,1504,2395,1048,55,1237,374,112,168,1330,2357,2360,459,526,156,2902,1772,1941,1969,560,746,28,75,1563,2169,731,1527,59,2760
|
2.687053265961324,2.311381403119757,-0.3543756565400391,0.7862799512775219,2.311381403119757,-0.2661038286652666,1.016858162020565,0.5297381122387874,-0.5338093246549072,-0.37659150480827835,-1.2202811138168626,-0.3988673947128502,-0.44360111347426245,-0.31012230394858126,0.44930601055840114,-0.1787578934323262,0.8057169414204521,0.9597505084681618,1.2603787307732723,0.9214825561524033,-0.1787578934323262,0.7668015426370355,-0.48858049757519073,-2.2268000244687314,1.278853689347875,0.12003241207649194,-1.3702552416869775,-0.31012230394858126,1.278853689347875,-0.48858049757519073,-0.6710317035777431,-0.31012230394858126,-0.5111634909229179,-1.785701460422968,-1.42092054737106,-0.0708373510934119,-0.15706295482882135,0.014520145426408674,-0.04941754059447337,-1.146393653735946,-0.8106447024352365,0.40881543685910227,0.014520145426408674,-0.5111634909229179,0.30676947108334135,2.4599952437757544,0.18272500423106916,0.9597505084681618,1.8695290813707817,1.5338312891339945,0.12003241207649194,-0.48858049757519073,-0.48858049757519073,0.8251127563510817,0.7472814698483077,1.6054641390302427,-1.0248100286459398,-0.1138401084971145,-0.20050904201939973,-0.22231680626932795,0.7081153372030551,0.5297381122387874,3.15792453539255,2.2613651972231907,-0.006739164246572185,-0.3543756565400391,0.5497334133991656,0.014520145426408674,2.4435871616487934,-0.8341541839153083
| 3,210
|
Primary active transmembrane transporter activity
| 17
| 56
| 2.565379
| 0.010306
|
Q9P0J0,P31930,P23634,P14854,O75027,O43676,Q9UDW1,P33527,P08183,P16615,P20674,P13073,P00403,P03886,O95298,O75306,Q9HD20
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
33,220,219,229,333,41,75,267,113,397,498,370,334,152,282,464,28
|
996,2657,2108,1867,41,1281,333,1416,464,711,1487,282,690,334,152,734,2416,2993,113,823,1873,370,229,397,2603,1875,498,2339,3160,219,1422,3117,220,267,1700,2571,2084,2383,1426,573,2691,1622,2732,1108,2087,860,2887,2500,1237,28,1524,33,75,1563,1527,530
|
0.32727353035340734,-0.740532149740219,-0.332219403312167,-0.1787578934323262,2.814646690863611,0.14098048384438178,1.016858162020565,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,1.1300357877506997,0.5696841825408305,1.016858162020565,1.6232905049437316,0.5297381122387874,-0.5338093246549072,-1.2202811138168626,1.8521420832959734,0.44930601055840114,-0.1787578934323262,0.9597505084681618,1.2603787307732723,0.9214825561524033,-0.6941314197209414,-0.1787578934323262,0.7668015426370355,-0.48858049757519073,-2.2268000244687314,1.278853689347875,0.05688083594047554,-1.8124742250552148,1.278853689347875,1.1674604442373642,-0.09231141282339332,-0.6710317035777431,-0.31012230394858126,-0.5111634909229179,0.05688083594047554,0.6884687739263295,-0.7638342514312623,-0.04941754059447337,-0.8106447024352365,0.26561689337391103,-0.31012230394858126,0.4290838414759394,-1.0007215188288232,-0.6021287719704128,0.18272500423106916,3.15792453539255,0.014520145426408674,2.956395767747345,2.2613651972231907,-0.006739164246572185,0.014520145426408674,0.7472814698483077
| 3,210
|
Sphingolipid metabolism
| 6
| 13
| 2.55652
| 0.010572
|
O95470,O43681,O15121,Q16739,Q13510,Q06136
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
35,104,108,44,304,155
|
108,611,1825,104,35,325,2764,3056,1492,155,304,44,1646
|
1.8868858346923807,0.64904737623524,-0.15706295482882135,1.9387760747315386,2.9093530775549494,1.0358164604588085,-0.8577339369682366,-1.4463831438360908,0.014520145426408674,1.6054641390302427,1.092461638717988,2.6709959483183634,-0.04941754059447337
| 3,210
|
Intrinsic component of endoplasmic reticulum membrane
| 18
| 55
| 2.554593
| 0.010631
|
P10321,O95470,Q8TB61,Q9Y282,Q9Y4P3,Q8N4V1,P04439,O43402,Q9P035,Q9NQC3,Q96A33,O75844,Q15629,Q9GZP9,Q969X5,O00767,Q12981,Q86XL3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
320,35,163,332,432,168,449,423,377,82,375,20,22,119,579,189,576,31
|
1947,189,1280,423,1652,20,1001,35,789,449,320,2922,695,1531,2384,672,2960,1108,2087,576,2428,802,22,2152,1172,1235,3015,31,168,2457,163,3003,2674,579,375,2292,1440,1998,1857,2068,119,3175,1677,599,991,82,2044,1180,377,2904,1215,2169,332,432,2414
|
-0.22231680626932795,1.4071872159758687,0.14098048384438178,0.8637818220779606,-0.0708373510934119,3.535416449055476,0.32727353035340734,2.9093530775549494,0.4694822353754309,0.8251127563510817,1.0547363295691754,-1.0732132719357752,0.5696841825408305,-0.006739164246572185,-0.5111634909229179,0.5895906935815504,-1.146393653735946,0.26561689337391103,-0.31012230394858126,0.6884687739263295,-0.5338093246549072,0.4694822353754309,3.3407208935166444,-0.3543756565400391,0.22426959652252174,0.18272500423106916,-1.2699417243874822,2.987644251860881,1.5338312891339945,-0.556518486029154,1.5517889434452048,-1.2450707022746819,-0.740532149740219,0.6884687739263295,0.9597505084681618,-0.44360111347426245,0.05688083594047554,-0.24418159668346107,-0.15706295482882135,-0.28808392260207233,1.8172767653783097,-2.547439296229894,-0.0708373510934119,0.6687795395939293,0.34772985125492284,2.1942959806671287,-0.2661038286652666,0.22426959652252174,0.9597505084681618,-1.0248100286459398,0.20352212550695528,-0.3543756565400391,1.0358164604588085,0.8637818220779606,-0.5111634909229179
| 3,210
|
Cns demyelination
| 6
| 14
| 2.544066
| 0.010957
|
P51648,Q9H9P8,P49770,P40855,P07602,Q15067
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
101,202,203,239,335,60
|
335,1700,239,2606,203,101,798,360,1325,60,740,202,1214,686
|
1.016858162020565,-0.09231141282339332,1.2233207047385817,-0.6941314197209414,1.352397648067967,1.9903992795510101,0.4694822353754309,0.9788254062828049,0.12003241207649194,2.410693261639707,0.5297381122387874,1.37069561369251,0.20352212550695528,0.5895906935815504
| 3,210
|
Organic acid transport
| 13
| 45
| 2.540737
| 0.011062
|
Q9H2D1,O43772,P04083,O60831,P33527,P53985,Q6P4A7,Q9UBX3,Q7L0J3,P08183,Q96NB2,Q9Y619,P23786
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,66,568,478,267,145,440,50,84,113,526,59,312
|
2108,565,1867,66,2134,478,2050,2627,1530,1829,568,2553,693,113,2080,735,2019,312,1422,3018,2083,1699,1136,267,1700,912,2445,145,1658,775,2284,1200,440,84,526,1937,1,1772,1941,1969,844,50,2877,3125,59
|
-0.332219403312167,0.6884687739263295,-0.1787578934323262,2.311381403119757,-0.3543756565400391,0.7862799512775219,-0.28808392260207233,-0.7172980550040869,-0.006739164246572185,-0.15706295482882135,0.6884687739263295,-0.6479983733197957,0.5696841825408305,1.8521420832959734,-0.31012230394858126,0.5297381122387874,-0.2661038286652666,1.0736179845718188,0.05688083594047554,-1.2948949262443985,-0.31012230394858126,-0.09231141282339332,0.2449677445585254,1.1674604442373642,-0.09231141282339332,0.3885005023995106,-0.556518486029154,1.6588461750842975,-0.0708373510934119,0.4896128041999829,-0.44360111347426245,0.20352212550695528,0.8444676370207627,2.160595878265183,0.7472814698483077,-0.20050904201939973,5.424065052068769,-0.1138401084971145,-0.20050904201939973,-0.22231680626932795,0.44930601055840114,2.557906632557138,-0.9767075535898113,-1.866323431141539,2.4435871616487934
| 3,210
|
Attachment of spindle microtubules to kinetochore
| 8
| 22
| 2.516618
| 0.011849
|
Q00839,P60953,Q9HC35,Q14457,O43670,Q8IXJ6,Q9P258,Q8NBT2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
286,574,131,419,566,211,251,159
|
566,585,1131,2854,574,286,419,1298,2116,211,159,1808,1964,1598,1763,1441,1909,1086,1817,1602,131,251
|
0.6884687739263295,0.6687795395939293,0.2449677445585254,-0.9527674967759283,0.6884687739263295,1.1300357877506997,0.8830555478987258,0.14098048384438178,-0.332219403312167,1.3156964634073816,1.5697135245345106,-0.13542382527329797,-0.22231680626932795,-0.028051602989249587,-0.1138401084971145,0.05688083594047554,-0.1787578934323262,0.286217363258279,-0.13542382527329797,-0.028051602989249587,1.747176663755568,1.204737245801071
| 3,210
|
Carboxylic acid transport
| 14
| 32
| 2.513624
| 0.01195
|
Q9H2D1,P04083,P14174,Q02978,O14745,O60831,P33527,P53985,Q9UBX3,Q7L0J3,Q96NB2,P07602,Q9Y619,Q9NZJ7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,568,735,775,565,478,267,145,50,84,526,335,59,686
|
565,1867,478,2050,2627,568,2553,335,2080,735,2019,1422,2083,267,2445,145,1658,775,2284,1200,84,526,1937,1,1772,1941,1969,844,686,50,2877,59
|
0.6884687739263295,-0.1787578934323262,0.7862799512775219,-0.28808392260207233,-0.7172980550040869,0.6884687739263295,-0.6479983733197957,1.016858162020565,-0.31012230394858126,0.5297381122387874,-0.2661038286652666,0.05688083594047554,-0.31012230394858126,1.1674604442373642,-0.556518486029154,1.6588461750842975,-0.0708373510934119,0.4896128041999829,-0.44360111347426245,0.20352212550695528,2.160595878265183,0.7472814698483077,-0.20050904201939973,5.424065052068769,-0.1138401084971145,-0.20050904201939973,-0.22231680626932795,0.44930601055840114,0.5895906935815504,2.557906632557138,-0.9767075535898113,2.4435871616487934
| 3,210
|
Protein localization
| 15
| 73
| 2.507792
| 0.012149
|
Q99595,Q5JRX3,P51648,Q9NS69,Q9NR77,P09601,O43681,Q10713,Q9Y584,P40855,Q08426,P21796,P46379,O15254,Q15067
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,257,101,6,136,169,104,171,13,239,80,19,214,245,60
|
995,1095,1255,2210,245,937,104,531,2134,2879,2595,2549,903,1977,2763,2050,1037,587,1222,2377,2993,823,3025,169,3100,467,2686,1067,19,634,3037,1422,1700,2869,3038,239,214,268,1103,101,1536,880,3104,80,171,3189,888,555,60,860,1047,257,1896,3128,402,837,702,1549,0,1936,1028,136,6,1819,2678,707,2877,3125,2789,2469,872,13,529
|
0.32727353035340734,0.26561689337391103,0.16187790183882575,-0.3988673947128502,1.204737245801071,0.36813874070508046,1.9387760747315386,0.7277194848631139,-0.3543756565400391,-1.0007215188288232,-0.6941314197209414,-0.6479983733197957,0.3885005023995106,-0.24418159668346107,-0.8577339369682366,-0.28808392260207233,0.30676947108334135,0.6687795395939293,0.18272500423106916,-0.5111634909229179,-1.2202811138168626,0.44930601055840114,-1.3199310652066065,1.515840391838553,-1.7059780565784959,0.8057169414204521,-0.7638342514312623,0.286217363258279,3.565072073980479,0.6292720233130275,-1.3702552416869775,0.05688083594047554,-0.09231141282339332,-0.9767075535898113,-1.3702552416869775,1.2233207047385817,1.297292869739083,1.1674604442373642,0.26561689337391103,1.9903992795510101,-0.006739164246572185,0.40881543685910227,-1.73245439296629,2.2111044701538995,1.497816080363346,-2.9478173975442443,0.40881543685910227,0.7081153372030551,2.410693261639707,0.4290838414759394,0.30676947108334135,1.1861172256824857,-0.1787578934323262,-1.8934020128115538,0.9214825561524033,0.44930601055840114,0.5696841825408305,-0.006739164246572185,6.587934544608236,-0.20050904201939973,0.32727353035340734,1.7119394487268482,4.959044238463191,-0.13542382527329797,-0.740532149740219,0.5696841825408305,-0.9767075535898113,-1.866323431141539,-0.8577339369682366,-0.556518486029154,0.4290838414759394,3.915034698124895,0.7472814698483077
| 3,210
|
Inorganic anion transport
| 8
| 24
| 2.505611
| 0.012224
|
O43681,Q9UHG3,P33527,Q9UBX3,P08183,P21796,P45880,P30536
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
104,14,267,50,113,19,52,91
|
275,1867,104,113,3142,19,2341,91,267,52,3048,1658,887,775,1048,3184,811,1251,1086,50,14,506,1688,2760
|
1.1487666995177788,-0.1787578934323262,1.9387760747315386,1.8521420832959734,-2.030379226705189,3.565072073980479,-0.48858049757519073,2.092859600557418,1.1674604442373642,2.509065367944047,-1.42092054737106,-0.0708373510934119,0.40881543685910227,0.4896128041999829,0.30676947108334135,-2.7908471566158775,0.4694822353754309,0.18272500423106916,0.286217363258279,2.557906632557138,3.886275851199562,0.7668015426370355,-0.0708373510934119,-0.8341541839153083
| 3,210
|
Netrinunc5b signaling pathway
| 8
| 13
| 2.487955
| 0.012848
|
P61586,P28482,P63000,P62136,Q06124,Q16539,P04637,Q8TCG1
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
193,635,636,204,663,339,466,522
|
466,2056,635,1007,717,193,204,636,1623,663,1471,339,522
|
0.8057169414204521,-0.28808392260207233,0.6292720233130275,0.32727353035340734,0.5497334133991656,1.4071872159758687,1.352397648067967,0.6292720233130275,-0.04941754059447337,0.6094532176877998,0.03572669165067375,1.016858162020565,0.7472814698483077
| 3,210
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 11
| 32
| 2.486142
| 0.012914
|
Q6UW02,Q14534,O75845,P09601,P07237,O15121,Q16850,Q15800,P16435,P30519,O00767
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
316,255,293,169,326,108,140,54,153,25,189
|
1412,2980,189,108,1187,2014,630,293,822,326,169,1577,153,3018,25,970,2392,2320,255,54,140,3095,780,316,621,1242,1810,2123,684,422,2171,1821
|
0.05688083594047554,-1.195572223965075,1.4071872159758687,1.8868858346923807,0.20352212550695528,-0.2661038286652666,0.6292720233130275,1.1112675033149844,0.44930601055840114,1.0358164604588085,1.515840391838553,-0.028051602989249587,1.6232905049437316,-1.2948949262443985,3.2649229530203527,0.34772985125492284,-0.5111634909229179,-0.46605986346971,1.1861172256824857,2.4927342354820032,1.6765758036559943,-1.65331482085283,0.4896128041999829,1.0736179845718188,0.64904737623524,0.18272500423106916,-0.13542382527329797,-0.332219403312167,0.5895906935815504,0.8830555478987258,-0.3543756565400391,-0.13542382527329797
| 3,210
|
Connective tissue development
| 6
| 28
| 2.481325
| 0.013089
|
P43490,P11802,P35610,O75844,P16435,O15173
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,144,83,20,153,120
|
120,1825,20,2052,185,2274,144,153,2729,2056,2315,83,4,1498,2637,663,2926,339,2697,1203,3004,1367,2914,1935,2928,1858,2123,2068
|
1.7997981488475483,-0.15706295482882135,3.535416449055476,-0.28808392260207233,1.4253812176403144,-0.44360111347426245,1.6588461750842975,1.6232905049437316,-0.8106447024352365,-0.28808392260207233,-0.46605986346971,2.1774598255807205,5.037758494615925,0.014520145426408674,-0.7172980550040869,0.6094532176877998,-1.0732132719357752,1.016858162020565,-0.7638342514312623,0.20352212550695528,-1.2450707022746819,0.09903334462182867,-1.0489737282202127,-0.20050904201939973,-1.0732132719357752,-0.15706295482882135,-0.332219403312167,-0.28808392260207233
| 3,210
|
Electron transport chain oxphos system in mitochondria
| 18
| 50
| 2.481095
| 0.013098
|
O75964,Q9Y6M9,P14406,P00403,P31930,P14854,O43676,Q9UDW1,O75947,O14949,P20674,P13073,P12235,P03886,O95298,O75306,P31040,P51970
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
67,530,5,334,220,229,41,75,479,76,498,370,467,152,282,464,435,573
|
996,2657,76,41,1281,1416,464,711,1487,1097,479,67,282,690,334,152,2180,2993,2685,1873,467,2686,370,5,229,875,1289,2603,498,1317,569,1318,3037,3117,435,220,2343,2383,3113,1426,573,1841,1500,2691,2887,2500,1237,75,2542,530
|
0.32727353035340734,-0.740532149740219,2.2446389541407687,2.814646690863611,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,0.26561689337391103,0.7862799512775219,2.311381403119757,1.1300357877506997,0.5696841825408305,1.016858162020565,1.6232905049437316,-0.37659150480827835,-1.2202811138168626,-0.7638342514312623,-0.1787578934323262,0.8057169414204521,-0.7638342514312623,0.9597505084681618,4.972198060062475,1.2603787307732723,0.40881543685910227,0.14098048384438178,-0.6941314197209414,0.7668015426370355,0.12003241207649194,0.6884687739263295,0.12003241207649194,-1.3702552416869775,-1.8124742250552148,0.8444676370207627,1.278853689347875,-0.48858049757519073,-0.5111634909229179,-1.785701460422968,0.05688083594047554,0.6884687739263295,-0.15706295482882135,0.014520145426408674,-0.7638342514312623,-1.0007215188288232,-0.6021287719704128,0.18272500423106916,2.2613651972231907,-0.6250309026232277,0.7472814698483077
| 3,210
|
Cellular response to biotic stimulus
| 11
| 35
| 2.47937
| 0.013161
|
P61586,P26583,P09429,P11802,Q8IXJ6,Q9NQ88,Q16539,O75844,Q8WTV0,Q96A33,P30536
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
193,381,234,144,211,376,339,20,181,375,91
|
939,20,1001,466,1693,1576,234,144,735,1068,381,2056,635,91,1617,592,193,2773,339,3041,1544,806,2037,2403,211,2157,181,1722,375,1763,376,1059,2739,2169,2075
|
0.36813874070508046,3.535416449055476,0.32727353035340734,0.8057169414204521,-0.09231141282339332,-0.028051602989249587,1.2418678008603015,1.6588461750842975,0.5297381122387874,0.286217363258279,0.9406363002425452,-0.28808392260207233,0.6292720233130275,2.092859600557418,-0.04941754059447337,0.6687795395939293,1.4071872159758687,-0.8577339369682366,1.016858162020565,-1.3702552416869775,-0.006739164246572185,0.4694822353754309,-0.2661038286652666,-0.5111634909229179,1.3156964634073816,-0.3543756565400391,1.4616665228240524,-0.09231141282339332,0.9597505084681618,-0.1138401084971145,0.9597505084681618,0.30676947108334135,-0.8106447024352365,-0.3543756565400391,-0.28808392260207233
| 3,210
|
Oxidase
| 7
| 20
| 2.472584
| 0.013414
|
O75845,P14406,O43169,Q15800,O15260,O15254,Q15067
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
293,5,74,54,56,245,60
|
245,56,74,2177,293,1097,1873,3185,2309,5,1289,498,1836,382,2219,60,54,2779,2198,1775
|
1.204737245801071,2.4435871616487934,2.2613651972231907,-0.37659150480827835,1.1112675033149844,0.26561689337391103,-0.1787578934323262,-2.82193125538963,-0.46605986346971,4.972198060062475,0.14098048384438178,0.7668015426370355,-0.15706295482882135,0.9406363002425452,-0.3988673947128502,2.410693261639707,2.4927342354820032,-0.8577339369682366,-0.37659150480827835,-0.1138401084971145
| 3,210
|
Inner mitochondrial membrane protein complex
| 22
| 75
| 2.471106
| 0.01347
|
Q99595,Q9Y6M9,P14406,Q9Y584,P03886,O95298,Q9P0J0,Q13505,O43676,Q86Y39,P31040,P51970,O75964,Q9UDW1,O14949,P00403,O75306,P31930,P14854,O75947,P20674,P13073
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,530,5,13,152,282,33,555,41,174,435,573,67,75,76,334,464,220,229,479,498,370
|
996,2657,1255,76,41,1281,1416,464,711,903,1487,479,67,282,690,334,152,2993,823,2685,1873,2686,370,5,229,875,1289,2603,498,1317,569,1318,3037,3117,435,220,3010,2343,3038,2383,3113,1426,573,1841,1500,2691,555,2887,2500,2285,1047,1989,804,1020,174,2699,1330,702,762,2915,0,2976,2066,682,1028,2436,2919,1819,33,75,2789,1278,872,13,530
|
0.32727353035340734,-0.740532149740219,0.16187790183882575,2.2446389541407687,2.814646690863611,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.3885005023995106,0.014520145426408674,0.7862799512775219,2.311381403119757,1.1300357877506997,0.5696841825408305,1.016858162020565,1.6232905049437316,-1.2202811138168626,0.44930601055840114,-0.7638342514312623,-0.1787578934323262,-0.7638342514312623,0.9597505084681618,4.972198060062475,1.2603787307732723,0.40881543685910227,0.14098048384438178,-0.6941314197209414,0.7668015426370355,0.12003241207649194,0.6884687739263295,0.12003241207649194,-1.3702552416869775,-1.8124742250552148,0.8444676370207627,1.278853689347875,-1.2699417243874822,-0.48858049757519073,-1.3702552416869775,-0.5111634909229179,-1.785701460422968,0.05688083594047554,0.6884687739263295,-0.15706295482882135,0.014520145426408674,-0.7638342514312623,0.7081153372030551,-1.0007215188288232,-0.6021287719704128,-0.44360111347426245,0.30676947108334135,-0.24418159668346107,0.4694822353754309,0.32727353035340734,1.4797581820627799,-0.7638342514312623,0.12003241207649194,0.5696841825408305,0.5096980023516975,-1.0489737282202127,6.587934544608236,-1.1709433084847787,-0.28808392260207233,0.5895906935815504,0.32727353035340734,-0.5338093246549072,-1.0489737282202127,-0.13542382527329797,2.956395767747345,2.2613651972231907,-0.8577339369682366,0.16187790183882575,0.4290838414759394,3.915034698124895,0.7472814698483077
| 3,210
|
Protein insertion into membrane
| 7
| 30
| 2.459713
| 0.013905
|
Q9P0J0,Q9NS69,Q8N4V1,O43681,Q9Y584,Q15070,Q15629
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,6,168,104,13,45,22
|
848,423,104,531,587,1654,2898,1356,214,2960,2193,802,45,22,1989,1172,1235,3128,168,2457,3080,2988,375,991,6,33,2789,872,13,529
|
0.4290838414759394,0.8637818220779606,1.9387760747315386,0.7277194848631139,0.6687795395939293,-0.0708373510934119,-1.0248100286459398,0.09903334462182867,1.297292869739083,-1.146393653735946,-0.37659150480827835,0.4694822353754309,2.6065219729812474,3.3407208935166444,-0.24418159668346107,0.22426959652252174,0.18272500423106916,-1.8934020128115538,1.5338312891339945,-0.556518486029154,-1.5491193478204588,-1.195572223965075,0.9597505084681618,0.34772985125492284,4.959044238463191,2.956395767747345,-0.8577339369682366,0.4290838414759394,3.915034698124895,0.7472814698483077
| 3,210
|
Inorganic molecular entity transmembrane transporter activity
| 23
| 76
| 2.403786
| 0.016226
|
P33527,P21796,P16615,O00299,Q9HD20,Q8N4V1,O00400,Q9UBX3,P45880,Q93050,O75964,Q9UDW1,P00403,P12235,P31930,P23634,P14854,O43681,O75947,Q8N1S5,Q9Y277,Q8IUH4,P13073
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
267,19,397,275,28,168,43,50,52,459,67,75,334,467,220,219,229,104,479,112,506,374,370
|
275,43,1867,104,479,67,2016,334,734,2416,2180,2993,2212,2274,2080,823,3142,1873,467,370,229,397,1875,498,2339,3160,19,219,1318,3037,220,267,2343,2571,2084,52,2383,3113,3048,1658,1841,1500,1622,2960,2732,887,775,1504,2395,1048,3184,1237,374,112,168,1330,2360,459,811,2065,1251,2902,1772,1941,560,28,2919,50,75,1563,2169,506,731,1527,1688,2760
|
1.1487666995177788,2.687053265961324,-0.1787578934323262,1.9387760747315386,0.7862799512775219,2.311381403119757,-0.2661038286652666,1.016858162020565,0.5297381122387874,-0.5338093246549072,-0.37659150480827835,-1.2202811138168626,-0.3988673947128502,-0.44360111347426245,-0.31012230394858126,0.44930601055840114,-2.030379226705189,-0.1787578934323262,0.8057169414204521,0.9597505084681618,1.2603787307732723,0.9214825561524033,-0.1787578934323262,0.7668015426370355,-0.48858049757519073,-2.2268000244687314,3.565072073980479,1.278853689347875,0.12003241207649194,-1.3702552416869775,1.278853689347875,1.1674604442373642,-0.48858049757519073,-0.6710317035777431,-0.31012230394858126,2.509065367944047,-0.5111634909229179,-1.785701460422968,-1.42092054737106,-0.0708373510934119,-0.15706295482882135,0.014520145426408674,-0.04941754059447337,-1.146393653735946,-0.8106447024352365,0.40881543685910227,0.4896128041999829,0.014520145426408674,-0.5111634909229179,0.30676947108334135,-2.7908471566158775,0.18272500423106916,0.9597505084681618,1.8695290813707817,1.5338312891339945,0.12003241207649194,-0.48858049757519073,0.8251127563510817,0.4694822353754309,-0.28808392260207233,0.18272500423106916,-1.0248100286459398,-0.1138401084971145,-0.20050904201939973,0.7081153372030551,3.15792453539255,-1.0489737282202127,2.557906632557138,2.2613651972231907,-0.006739164246572185,-0.3543756565400391,0.7668015426370355,0.5497334133991656,0.014520145426408674,-0.0708373510934119,-0.8341541839153083
| 3,210
|
Response to arsenic containing substance
| 8
| 14
| 2.402384
| 0.016289
|
Q9H2U1,P36551,Q13535,P09601,Q9BWF3,P09651,O00571,P30405
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
390,382,361,169,142,713,747,434
|
747,1100,169,713,434,382,1191,1881,799,361,142,1408,390,1686
|
0.5096980023516975,0.26561689337391103,1.515840391838553,0.5497334133991656,0.8444676370207627,0.9406363002425452,0.20352212550695528,-0.1787578934323262,0.4694822353754309,0.9788254062828049,1.6765758036559943,0.07798293576717874,0.9406363002425452,-0.0708373510934119
| 3,210
|
Cellular response to oxygen levels
| 12
| 34
| 2.400031
| 0.016394
|
Q8N511,O94966,Q9Y4P3,P09601,P07237,P00558,O95352,Q8IXJ6,Q96A26,Q9NQ88,P04637,Q99808
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,294,432,169,326,355,354,211,18,376,466,156
|
464,294,354,1742,355,2881,466,2742,326,169,1953,2084,1702,2420,1165,1104,1622,2151,1019,2120,211,3,18,1935,2809,2976,156,684,376,3023,899,731,3024,432
|
0.8057169414204521,1.1112675033149844,0.9788254062828049,-0.1138401084971145,0.9788254062828049,-1.0007215188288232,0.8057169414204521,-0.8341541839153083,1.0358164604588085,1.515840391838553,-0.22231680626932795,-0.31012230394858126,-0.09231141282339332,-0.5338093246549072,0.22426959652252174,0.26561689337391103,-0.04941754059447337,-0.3543756565400391,0.32727353035340734,-0.332219403312167,1.3156964634073816,5.180787262938392,3.7268039481622726,-0.20050904201939973,-0.8813845471104144,-1.1709433084847787,1.6054641390302427,0.5895906935815504,0.9597505084681618,-1.2948949262443985,0.40881543685910227,0.5497334133991656,-1.2948949262443985,0.8637818220779606
| 3,210
|
Calcium-binding protein
| 6
| 15
| 2.394968
| 0.016622
|
Q02818,P60660,P80303,P43307,P31949,O43852
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
63,222,12,86,277,408
|
408,2922,277,86,222,12,63,472,1327,2644,2699,1805,2066,1443,1276
|
0.9022890486166665,-1.0732132719357752,1.1487666995177788,2.143704011138066,1.278853689347875,4.071945485745097,2.3279997010255387,0.8057169414204521,0.12003241207649194,-0.7172980550040869,-0.7638342514312623,-0.13542382527329797,-0.28808392260207233,0.05688083594047554,0.16187790183882575
| 3,210
|
Protein methyltransferase activity
| 7
| 26
| 2.394234
| 0.016655
|
Q9BV86,O60725,Q14166,Q6P2P2,Q9H7B4,Q86X55,Q9H993
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
39,40,278,281,243,122,391
|
819,2894,1221,40,940,1743,1494,2113,2191,2530,278,2283,831,2499,1397,281,1712,122,1204,864,460,39,243,391,1447,1606
|
0.44930601055840114,-1.0248100286459398,0.18272500423106916,2.8463083615822415,0.36813874070508046,-0.1138401084971145,0.014520145426408674,-0.332219403312167,-0.37659150480827835,-0.6250309026232277,1.1487666995177788,-0.44360111347426245,0.44930601055840114,-0.6021287719704128,0.07798293576717874,1.1487666995177788,-0.09231141282339332,1.7997981488475483,0.20352212550695528,0.4290838414759394,0.8251127563510817,2.877876905289693,1.2233207047385817,0.9406363002425452,0.05688083594047554,-0.028051602989249587
| 3,210
|
primary active transporter
| 11
| 24
| 2.389701
| 0.016862
|
P23634,Q9NS69,Q8N4H5,O60888,Q6P4A7,P09132,Q8TAA5,P16615,O94826,Q9GZP9,Q96NB2
|
Functions
|
Panther Protein class
|
panther_protein_class
|
219,6,402,139,440,177,702,397,587,119,526
|
139,2595,587,1222,734,2416,177,2632,397,1875,219,1358,2732,860,440,402,702,526,1857,119,1772,1969,1028,6
|
1.6765758036559943,-0.6941314197209414,0.6687795395939293,0.18272500423106916,0.5297381122387874,-0.5338093246549072,1.4616665228240524,-0.7172980550040869,0.9214825561524033,-0.1787578934323262,1.278853689347875,0.09903334462182867,-0.8106447024352365,0.4290838414759394,0.8444676370207627,0.9214825561524033,0.5696841825408305,0.7472814698483077,-0.15706295482882135,1.8172767653783097,-0.1138401084971145,-0.22231680626932795,0.32727353035340734,4.959044238463191
| 3,210
|
External ophthalmoplegia
| 10
| 17
| 2.375817
| 0.01751
|
Q8N183,P12235,Q13472,O95352,P51530,P26640,P00403,P03886,Q14331,P31040
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
835,467,858,354,617,614,334,152,287,435
|
1611,354,334,152,467,1317,614,435,2114,617,1985,858,287,1435,835,1114,899
|
-0.04941754059447337,0.9788254062828049,1.016858162020565,1.6232905049437316,0.8057169414204521,0.12003241207649194,0.64904737623524,0.8444676370207627,-0.332219403312167,0.64904737623524,-0.24418159668346107,0.4290838414759394,1.1300357877506997,0.05688083594047554,0.44930601055840114,0.26561689337391103,0.40881543685910227
| 3,210
|
Cytochrome complex
| 8
| 18
| 2.362252
| 0.018164
|
P31930,P14406,P14854,Q9UDW1,O14949,P20674,P13073,P00403
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
220,5,229,75,76,498,370,334
|
2657,76,334,823,2685,1873,370,5,229,875,1289,498,569,220,2383,1237,75,2789
|
-0.740532149740219,2.2446389541407687,1.016858162020565,0.44930601055840114,-0.7638342514312623,-0.1787578934323262,0.9597505084681618,4.972198060062475,1.2603787307732723,0.40881543685910227,0.14098048384438178,0.7668015426370355,0.6884687739263295,1.278853689347875,-0.5111634909229179,0.18272500423106916,2.2613651972231907,-0.8577339369682366
| 3,210
|
Respiratory chain
| 16
| 32
| 2.359684
| 0.018291
|
Q9P0J0,P31930,Q9Y6M9,P22695,O43676,Q9UDW1,Q6DKK2,O14949,P51970,Q86Y39,O75380,P00403,P03886,O95298,O75306,O95299
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
33,220,530,569,41,75,439,76,573,174,711,334,152,282,464,690
|
996,2657,76,41,1281,1416,464,711,1487,282,690,334,152,823,875,2603,569,3117,220,2383,1426,573,2691,2887,2500,439,174,762,33,75,1647,530
|
0.32727353035340734,-0.740532149740219,2.2446389541407687,2.814646690863611,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,1.1300357877506997,0.5696841825408305,1.016858162020565,1.6232905049437316,0.44930601055840114,0.40881543685910227,-0.6941314197209414,0.6884687739263295,-1.8124742250552148,1.278853689347875,-0.5111634909229179,0.05688083594047554,0.6884687739263295,-0.7638342514312623,-1.0007215188288232,-0.6021287719704128,0.8444676370207627,1.4797581820627799,0.5096980023516975,2.956395767747345,2.2613651972231907,-0.04941754059447337,0.7472814698483077
| 3,210
|
Organophosphate ester transport
| 7
| 27
| 2.350311
| 0.018758
|
Q9H2D1,Q8TB61,Q9BSK2,O00400,P08183,Q8WTV0,Q99808
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,163,9,43,113,181,156
|
43,1867,2134,3165,2180,113,467,2686,944,634,267,1700,1263,1042,2449,2935,1048,2671,1112,163,181,156,9,3106,1,746,2678
|
2.687053265961324,-0.1787578934323262,-0.3543756565400391,-2.3127380978900742,-0.37659150480827835,1.8521420832959734,0.8057169414204521,-0.7638342514312623,0.36813874070508046,0.6292720233130275,1.1674604442373642,-0.09231141282339332,0.16187790183882575,0.30676947108334135,-0.556518486029154,-1.0975293235654124,0.30676947108334135,-0.740532149740219,0.26561689337391103,1.5517889434452048,1.4616665228240524,1.6054641390302427,4.268651553761713,-1.73245439296629,5.424065052068769,0.5297381122387874,-0.740532149740219
| 3,210
|
Cholesterol metabolism with bloch and kandutschrussell pathways
| 8
| 25
| 2.323385
| 0.020158
|
Q15392,Q14534,O75845,Q16850,P35610,Q15800,Q14739,O00767
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
100,255,293,140,83,54,315,189
|
189,710,293,1530,1285,822,396,1697,1136,83,2572,2186,1165,2694,2426,577,255,315,2911,100,2718,54,140,1179,1215
|
1.4071872159758687,0.5497334133991656,1.1112675033149844,-0.006739164246572185,0.14098048384438178,0.44930601055840114,0.9214825561524033,-0.09231141282339332,0.2449677445585254,2.1774598255807205,-0.6710317035777431,-0.37659150480827835,0.22426959652252174,-0.7638342514312623,-0.5338093246549072,0.6884687739263295,1.1861172256824857,1.0736179845718188,-1.0489737282202127,2.0075483284887525,-0.7872049149016607,2.4927342354820032,1.6765758036559943,0.22426959652252174,0.20352212550695528
| 3,210
|
Midbrain development
| 8
| 21
| 2.321336
| 0.020269
|
P60953,P61586,P14854,O14949,Q8IXJ6,Q04917,P12277,P63167
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
574,193,229,76,211,225,588,224
|
76,610,1487,2079,2082,1696,588,229,1318,1459,2315,574,193,2115,224,2884,225,1196,211,1367,2174
|
2.2446389541407687,0.64904737623524,0.014520145426408674,-0.31012230394858126,-0.31012230394858126,-0.09231141282339332,0.6687795395939293,1.2603787307732723,0.12003241207649194,0.03572669165067375,-0.46605986346971,0.6884687739263295,1.4071872159758687,-0.332219403312167,1.278853689347875,-1.0007215188288232,1.278853689347875,0.20352212550695528,1.3156964634073816,0.09903334462182867,-0.3543756565400391
| 3,210
|
Delusions
| 7
| 19
| 2.31925
| 0.020381
|
Q13144,Q9BQE5,O43681,P49770,P04062,P21964,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
360,2,104,203,325,301,335
|
2547,104,325,335,2569,3056,301,382,771,203,1357,360,1325,1022,1405,2,1214,686,2877
|
-0.6479983733197957,1.9387760747315386,1.0358164604588085,1.016858162020565,-0.6710317035777431,-1.4463831438360908,1.092461638717988,0.9406363002425452,0.4896128041999829,1.352397648067967,0.09903334462182867,0.9788254062828049,0.12003241207649194,0.32727353035340734,0.07798293576717874,5.245263938346782,0.20352212550695528,0.5895906935815504,-0.9767075535898113
| 3,210
|
Regulation of atp metabolic process
| 8
| 26
| 2.303875
| 0.02123
|
P61586,P14406,Q9BSK2,O75376,Q9NQ88,P00403,P30536,P30405
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
193,5,9,353,376,334,91,434
|
1313,1186,353,2050,334,466,2377,2742,942,5,2136,434,91,1700,2279,2660,3118,1881,2690,193,1849,1667,725,9,376,2542
|
0.12003241207649194,0.20352212550695528,0.9788254062828049,-0.28808392260207233,1.016858162020565,0.8057169414204521,-0.5111634909229179,-0.8341541839153083,0.36813874070508046,4.972198060062475,-0.3543756565400391,0.8444676370207627,2.092859600557418,-0.09231141282339332,-0.44360111347426245,-0.740532149740219,-1.8124742250552148,-0.1787578934323262,-0.7638342514312623,1.4071872159758687,-0.15706295482882135,-0.0708373510934119,0.5497334133991656,4.268651553761713,0.9597505084681618,-0.6250309026232277
| 3,210
|
Oxidative phosphorylation
| 19
| 59
| 2.303584
| 0.021246
|
Q9Y6M9,P14406,P03886,O95298,O43676,Q86Y39,P31040,P51970,Q93050,O75964,Q9UDW1,O14949,P00403,O75306,P31930,P14854,O75947,P20674,P13073
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
530,5,152,282,41,174,435,573,459,67,75,76,334,464,220,229,479,498,370
|
996,2657,76,41,1281,1416,464,711,1487,479,67,282,690,334,152,2993,823,2685,1873,370,5,229,875,1289,2603,498,2339,3160,1317,569,1318,3037,3117,435,220,2343,2571,2084,2383,3113,1426,573,1841,1500,2691,1622,1265,1019,2887,2500,1237,174,459,1555,75,1563,731,1527,530
|
0.32727353035340734,-0.740532149740219,2.2446389541407687,2.814646690863611,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,0.7862799512775219,2.311381403119757,1.1300357877506997,0.5696841825408305,1.016858162020565,1.6232905049437316,-1.2202811138168626,0.44930601055840114,-0.7638342514312623,-0.1787578934323262,0.9597505084681618,4.972198060062475,1.2603787307732723,0.40881543685910227,0.14098048384438178,-0.6941314197209414,0.7668015426370355,-0.48858049757519073,-2.2268000244687314,0.12003241207649194,0.6884687739263295,0.12003241207649194,-1.3702552416869775,-1.8124742250552148,0.8444676370207627,1.278853689347875,-0.48858049757519073,-0.6710317035777431,-0.31012230394858126,-0.5111634909229179,-1.785701460422968,0.05688083594047554,0.6884687739263295,-0.15706295482882135,0.014520145426408674,-0.7638342514312623,-0.04941754059447337,0.16187790183882575,0.32727353035340734,-1.0007215188288232,-0.6021287719704128,0.18272500423106916,1.4797581820627799,0.8251127563510817,-0.006739164246572185,2.2613651972231907,-0.006739164246572185,0.5497334133991656,0.014520145426408674,0.7472814698483077
| 3,210
|
Biological oxidations
| 12
| 43
| 2.297345
| 0.021599
|
Q96DG6,Q8TB61,Q9NUJ1,O00170,O43169,P21266,P10768,Q16850,P21964,P16435,Q15185,P07099
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
324,163,103,72,74,327,300,140,301,153,121,27
|
72,74,1096,1485,2473,1691,1283,2519,2942,2706,27,1832,851,300,1491,451,153,327,301,1786,770,1421,3201,1462,1191,2345,799,121,140,2576,2577,163,2097,2989,324,1551,1269,1084,386,2370,103,1726,2469
|
2.2780642718897113,2.2613651972231907,0.26561689337391103,0.014520145426408674,-0.5792914685282397,-0.09231141282339332,0.14098048384438178,-0.6250309026232277,-1.121922556458858,-0.7872049149016607,3.1732738631171533,-0.15706295482882135,0.4290838414759394,1.092461638717988,0.014520145426408674,0.8251127563510817,1.6232905049437316,1.0358164604588085,1.092461638717988,-0.13542382527329797,0.4896128041999829,0.05688083594047554,-4.132028136281565,0.03572669165067375,0.20352212550695528,-0.48858049757519073,0.4694822353754309,1.7997981488475483,1.6765758036559943,-0.6710317035777431,-0.6710317035777431,1.5517889434452048,-0.31012230394858126,-1.195572223965075,1.0547363295691754,-0.006739164246572185,0.16187790183882575,0.286217363258279,0.9406363002425452,-0.48858049757519073,1.9732209802963745,-0.09231141282339332,-0.556518486029154
| 3,210
|
Shoulder girdle muscle weakness
| 6
| 12
| 2.281397
| 0.022525
|
O14979,Q14331,P07602,P12235,P46976,P06753
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
107,287,335,467,313,283
|
107,283,335,467,1040,313,1881,287,1332,1114,686,1914
|
1.8868858346923807,1.1300357877506997,1.016858162020565,0.8057169414204521,0.30676947108334135,1.0736179845718188,-0.1787578934323262,1.1300357877506997,0.12003241207649194,0.26561689337391103,0.5895906935815504,-0.1787578934323262
| 3,210
|
Retinoblastoma gene in cancer
| 22
| 49
| 2.278635
| 0.022689
|
P06493,O14757,P26583,Q16204,P11802,O95067,P27694,P23921,P49642,Q14566,Q9Y619,P04818,P15927,O00311,P40938,P04637,Q14527,P00374,P09429,P26358,P56282,P52701
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
632,253,381,515,144,409,670,550,794,578,59,185,311,309,716,466,347,733,234,356,499,754
|
309,253,3146,409,2551,2110,733,466,185,632,234,1694,2497,144,1288,1131,311,2659,550,1069,1352,356,381,670,1354,2278,1226,1423,1581,1619,1981,716,794,754,499,1708,973,1503,830,1434,347,578,2773,515,2508,1603,2544,2245,59
|
1.0736179845718188,1.1861172256824857,-2.085931168920067,0.9022890486166665,-0.6479983733197957,-0.332219403312167,0.5297381122387874,0.8057169414204521,1.4253812176403144,0.6292720233130275,1.2418678008603015,-0.09231141282339332,-0.6021287719704128,1.6588461750842975,0.14098048384438178,0.2449677445585254,1.0736179845718188,-0.740532149740219,0.7081153372030551,0.286217363258279,0.09903334462182867,0.9788254062828049,0.9406363002425452,0.5895906935815504,0.09903334462182867,-0.44360111347426245,0.18272500423106916,0.05688083594047554,-0.028051602989249587,-0.04941754059447337,-0.24418159668346107,0.5497334133991656,0.4694822353754309,0.5096980023516975,0.7668015426370355,-0.09231141282339332,0.34772985125492284,0.014520145426408674,0.44930601055840114,0.05688083594047554,0.9978612170400448,0.6884687739263295,-0.8577339369682366,0.7472814698483077,-0.6021287719704128,-0.028051602989249587,-0.6250309026232277,-0.3988673947128502,2.4435871616487934
| 3,210
|
Mitophagy
| 6
| 11
| 2.273917
| 0.022971
|
Q9NS69,Q8N4H5,P21796,P67870,O94826,Q13501
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
6,402,19,303,587,438
|
587,2658,1222,1419,19,303,438,860,640,402,6
|
0.6687795395939293,-0.740532149740219,0.18272500423106916,0.05688083594047554,3.565072073980479,1.092461638717988,0.8444676370207627,0.4290838414759394,0.6292720233130275,0.9214825561524033,4.959044238463191
| 3,210
|
Response to oxygen levels
| 18
| 64
| 2.27211
| 0.02308
|
P61586,Q8N511,Q14457,O94966,Q9Y4P3,P09601,P07237,P00558,O95352,Q8IXJ6,Q96A26,Q92544,P52789,Q9NQ88,P78536,P04637,P30519,Q99808
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
193,3,419,294,432,169,326,355,354,211,18,212,210,376,248,466,25,156
|
934,2980,1035,464,630,294,354,1742,355,1490,2881,2943,3108,466,2416,2742,326,169,2276,1068,1380,1133,2019,1953,25,1291,2688,2084,1702,717,2420,1165,2910,210,1104,1622,193,248,2392,776,419,2395,2151,1019,2120,780,211,3,2584,212,2289,18,1935,2809,2976,1248,156,684,376,3023,899,731,3024,432
|
0.36813874070508046,-1.195572223965075,0.30676947108334135,0.8057169414204521,0.6292720233130275,1.1112675033149844,0.9788254062828049,-0.1138401084971145,0.9788254062828049,0.014520145426408674,-1.0007215188288232,-1.121922556458858,-1.7590285248459558,0.8057169414204521,-0.5338093246549072,-0.8341541839153083,1.0358164604588085,1.515840391838553,-0.44360111347426245,0.286217363258279,0.07798293576717874,0.2449677445585254,-0.2661038286652666,-0.22231680626932795,3.2649229530203527,0.14098048384438178,-0.7638342514312623,-0.31012230394858126,-0.09231141282339332,0.5497334133991656,-0.5338093246549072,0.22426959652252174,-1.0489737282202127,1.3156964634073816,0.26561689337391103,-0.04941754059447337,1.4071872159758687,1.204737245801071,-0.5111634909229179,0.4896128041999829,0.8830555478987258,-0.5111634909229179,-0.3543756565400391,0.32727353035340734,-0.332219403312167,0.4896128041999829,1.3156964634073816,5.180787262938392,-0.6710317035777431,1.3156964634073816,-0.44360111347426245,3.7268039481622726,-0.20050904201939973,-0.8813845471104144,-1.1709433084847787,0.18272500423106916,1.6054641390302427,0.5895906935815504,0.9597505084681618,-1.2948949262443985,0.40881543685910227,0.5497334133991656,-1.2948949262443985,0.8637818220779606
| 3,210
|
Mitochondrial respiratory chain complex assembly
| 6
| 37
| 2.258437
| 0.023918
|
Q9P0J0,Q9BSK2,O43676,Q15070,Q69YU5,P03886
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,9,41,45,15,152
|
996,41,2177,1281,1416,464,1487,1097,282,690,1742,152,3117,2383,573,2691,2350,45,2887,2500,15,439,174,1715,835,3080,2583,762,9,1056,1775,2206,33,2789,651,872,530
|
0.32727353035340734,2.814646690863611,-0.37659150480827835,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.014520145426408674,0.26561689337391103,1.1300357877506997,0.5696841825408305,-0.1138401084971145,1.6232905049437316,-1.8124742250552148,-0.5111634909229179,0.6884687739263295,-0.7638342514312623,-0.48858049757519073,2.6065219729812474,-1.0007215188288232,-0.6021287719704128,3.8718695071919407,0.8444676370207627,1.4797581820627799,-0.09231141282339332,0.44930601055840114,-1.5491193478204588,-0.6710317035777431,0.5096980023516975,4.268651553761713,0.30676947108334135,-0.1138401084971145,-0.37659150480827835,2.956395767747345,-0.8577339369682366,0.6292720233130275,0.4290838414759394,0.7472814698483077
| 3,210
|
Scaffold protein binding
| 8
| 23
| 2.254137
| 0.024188
|
O15111,P23634,Q8IWS0,Q15334,P46108,P07602,Q16543,Q9UQB8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
292,219,106,399,302,335,348,62
|
1484,292,787,335,1654,1693,1576,1259,534,943,219,302,2115,1623,2772,2395,399,348,106,2675,686,62,933
|
0.014520145426408674,1.1112675033149844,0.4694822353754309,1.016858162020565,-0.0708373510934119,-0.09231141282339332,-0.028051602989249587,0.16187790183882575,0.7277194848631139,0.36813874070508046,1.278853689347875,1.092461638717988,-0.332219403312167,-0.04941754059447337,-0.8577339369682366,-0.5111634909229179,0.9214825561524033,0.9978612170400448,1.9387760747315386,-0.740532149740219,0.5895906935815504,2.3445913132180505,0.3885005023995106
| 3,210
|
Stem cell proliferation
| 6
| 13
| 2.251169
| 0.024375
|
Q00839,Q9Y5A9,P26583,P04062,P08183,O95376
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
286,367,381,325,113,533
|
1187,548,533,325,113,1006,381,1788,1071,286,1929,865,367
|
0.20352212550695528,0.7081153372030551,0.7277194848631139,1.0358164604588085,1.8521420832959734,0.32727353035340734,0.9406363002425452,-0.13542382527329797,0.286217363258279,1.1300357877506997,-0.20050904201939973,0.4290838414759394,0.9788254062828049
| 3,210
|
Steroid binding
| 11
| 23
| 2.238882
| 0.025164
|
O95772,P04062,P38435,P21796,P45880,P35610,O00264,O15173,O15118,P04150,P30536
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
631,325,207,19,52,83,115,120,493,465,91
|
115,493,120,1612,1917,631,325,465,734,2274,19,944,634,91,83,207,52,1042,2935,2916,1057,3106,2564
|
1.8172767653783097,0.7668015426370355,1.7997981488475483,-0.04941754059447337,-0.20050904201939973,0.6292720233130275,1.0358164604588085,0.8057169414204521,0.5297381122387874,-0.44360111347426245,3.565072073980479,0.36813874070508046,0.6292720233130275,2.092859600557418,2.1774598255807205,1.3340646601393549,2.509065367944047,0.30676947108334135,-1.0975293235654124,-1.0489737282202127,0.30676947108334135,-1.73245439296629,-0.6479983733197957
| 3,210
|
Left ventricular hypertrophy
| 8
| 24
| 2.225785
| 0.026029
|
Q15233,P12235,O00170,P40939,P78536,P00403,P03886,P31040
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
485,467,72,170,248,334,152,435
|
72,903,495,1097,334,152,2764,1695,467,1418,1317,435,170,2481,248,1985,1928,485,2671,2286,1804,839,1114,1446
|
2.2780642718897113,0.3885005023995106,0.7668015426370355,0.26561689337391103,1.016858162020565,1.6232905049437316,-0.8577339369682366,-0.09231141282339332,0.8057169414204521,0.05688083594047554,0.12003241207649194,0.8444676370207627,1.515840391838553,-0.5792914685282397,1.204737245801071,-0.24418159668346107,-0.20050904201939973,0.7862799512775219,-0.740532149740219,-0.44360111347426245,-0.13542382527329797,0.44930601055840114,0.26561689337391103,0.05688083594047554
| 3,210
|
Positive regulation of macroautophagy
| 11
| 24
| 2.221433
| 0.026322
|
P68402,Q14457,P27544,P09601,P42858,O60858,O15269,P21796,Q6PKG0,P12235,Q9H2M9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
346,419,296,169,771,424,611,19,757,467,745
|
1483,611,1825,787,424,2017,2180,2111,169,467,19,2056,296,771,2218,1009,346,419,2284,757,2038,1935,745,2172
|
0.014520145426408674,0.64904737623524,-0.15706295482882135,0.4694822353754309,0.8637818220779606,-0.2661038286652666,-0.37659150480827835,-0.332219403312167,1.515840391838553,0.8057169414204521,3.565072073980479,-0.28808392260207233,1.1112675033149844,0.4896128041999829,-0.3988673947128502,0.32727353035340734,0.9978612170400448,0.8830555478987258,-0.44360111347426245,0.5096980023516975,-0.2661038286652666,-0.20050904201939973,0.5297381122387874,-0.3543756565400391
| 3,210
|
Reductase
| 8
| 16
| 2.217184
| 0.026611
|
Q9H7Z7,Q15392,Q9UDW1,P14550,P23921,Q14739,P15121,O95881
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
34,100,75,451,550,315,371,691
|
1485,3017,691,733,451,875,371,550,1787,1354,315,100,1804,34,1215,75
|
0.014520145426408674,-1.2948949262443985,0.5696841825408305,0.5297381122387874,0.8251127563510817,0.40881543685910227,0.9597505084681618,0.7081153372030551,-0.13542382527329797,0.09903334462182867,1.0736179845718188,2.0075483284887525,-0.13542382527329797,2.9250567577732913,0.20352212550695528,2.2613651972231907
| 3,210
|
Abnormal circulating lipid concentration
| 17
| 80
| 2.204923
| 0.027459
|
P22830,O43772,O95470,Q8N511,Q15392,Q9Y285,O75845,P40939,P50402,P40855,Q08426,O75844,Q7L590,Q15800,Q96MF7,Q14739,P23786
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
96,66,35,3,100,195,293,170,268,239,80,20,148,54,183,315,312
|
1279,1035,66,2879,2595,903,20,293,1097,35,3165,2881,2764,1379,335,2602,3185,96,312,1460,1290,1699,1700,2523,751,2869,2572,3207,239,170,771,1656,773,2219,268,912,1103,1746,1536,915,2481,880,2028,1042,2693,1538,917,2836,80,1843,949,620,315,1326,100,2718,54,1019,2032,2398,1932,148,3,2873,725,1720,2674,183,2099,1775,1371,686,1215,1974,2877,195,2514,432,1914,2267
|
0.14098048384438178,0.30676947108334135,2.311381403119757,-1.0007215188288232,-0.6941314197209414,0.3885005023995106,3.535416449055476,1.1112675033149844,0.26561689337391103,2.9093530775549494,-2.3127380978900742,-1.0007215188288232,-0.8577339369682366,0.07798293576717874,1.016858162020565,-0.6941314197209414,-2.82193125538963,2.0246682647945144,1.0736179845718188,0.03572669165067375,0.14098048384438178,-0.09231141282339332,-0.09231141282339332,-0.6250309026232277,0.5096980023516975,-0.9767075535898113,-0.6710317035777431,-6.186759028341053,1.2233207047385817,1.515840391838553,0.4896128041999829,-0.0708373510934119,0.4896128041999829,-0.3988673947128502,1.1674604442373642,0.3885005023995106,0.26561689337391103,-0.1138401084971145,-0.006739164246572185,0.3885005023995106,-0.5792914685282397,0.40881543685910227,-0.2661038286652666,0.30676947108334135,-0.7638342514312623,-0.006739164246572185,0.3885005023995106,-0.9289007210857031,2.2111044701538995,-0.15706295482882135,0.36813874070508046,0.64904737623524,1.0736179845718188,0.12003241207649194,2.0075483284887525,-0.7872049149016607,2.4927342354820032,0.32727353035340734,-0.2661038286652666,-0.5111634909229179,-0.20050904201939973,1.6588461750842975,5.180787262938392,-0.9767075535898113,0.5497334133991656,-0.09231141282339332,-0.740532149740219,1.443540927049774,-0.31012230394858126,-0.1138401084971145,0.09903334462182867,0.5895906935815504,0.20352212550695528,-0.22231680626932795,-0.9767075535898113,1.4071872159758687,-0.6021287719704128,0.8637818220779606,-0.1787578934323262,-0.42120377836259065
| 3,210
|
Oxidoreduction driven active transmembrane transporter activity
| 12
| 30
| 2.193097
| 0.0283
|
Q9P0J0,P31930,Q9Y6M9,P14854,O43676,Q9UDW1,P20674,P13073,P00403,P03886,O95298,O75306
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
33,220,530,229,41,75,498,370,334,152,282,464
|
996,2657,41,1281,1416,464,711,1487,282,690,334,152,823,1873,370,229,2603,498,3117,220,2383,1426,573,2691,2887,2500,1237,33,75,530
|
0.32727353035340734,-0.740532149740219,2.814646690863611,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,1.1300357877506997,0.5696841825408305,1.016858162020565,1.6232905049437316,0.44930601055840114,-0.1787578934323262,0.9597505084681618,1.2603787307732723,-0.6941314197209414,0.7668015426370355,-1.8124742250552148,1.278853689347875,-0.5111634909229179,0.05688083594047554,0.6884687739263295,-0.7638342514312623,-1.0007215188288232,-0.6021287719704128,0.18272500423106916,2.956395767747345,2.2613651972231907,0.7472814698483077
| 3,210
|
Tetrapyrrole metabolic process
| 8
| 22
| 2.182579
| 0.029067
|
P22830,P09601,P33527,O00264,O75027,P30519,P30536,Q96EY8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,169,267,115,333,25,91,227
|
115,2108,333,2600,2569,169,96,1787,25,91,267,382,1357,796,1757,1237,227,1084,1524,3183,3042,2542
|
1.8172767653783097,-0.332219403312167,1.016858162020565,-0.6941314197209414,-0.6710317035777431,1.515840391838553,2.0246682647945144,-0.13542382527329797,3.2649229530203527,2.092859600557418,1.1674604442373642,0.9406363002425452,0.09903334462182867,0.4694822353754309,-0.1138401084971145,0.18272500423106916,1.278853689347875,0.286217363258279,0.014520145426408674,-2.7291293249888016,-1.3702552416869775,-0.6250309026232277
| 3,210
|
Thickened skin
| 27
| 100
| 2.172729
| 0.029801
|
P50402,P04066,O75844,P16615,Q9NX24,Q15555,Q06136,P15924,O95470,P09493,Q14574,Q15800,Q96MF7,Q14739,P31040,O43175,O00170,P04062,Q9Y2B2,Q8WWQ0,Q9H1A4,P42166,Q9NWM8,P51648,Q13642,P40855,Q96AX1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
268,265,20,397,415,412,155,534,35,549,179,54,183,315,435,190,72,325,606,473,597,85,95,101,620,239,525
|
72,1279,611,1825,1916,190,2879,2249,2595,903,20,2867,2251,35,2017,1978,1490,2881,325,265,2600,2764,2684,2852,549,1694,2520,1697,852,534,1492,397,2018,2708,1133,2709,2019,1317,2341,659,791,1460,1290,435,1699,239,85,1533,2186,1357,268,1103,101,2346,2057,880,1882,2732,1623,2392,2426,155,2667,2227,620,2558,179,315,2911,2118,412,2430,2718,54,920,1200,2503,982,2873,1206,473,1720,2617,525,1762,1853,183,2099,597,1305,3175,1815,1643,1724,95,415,606,2374,2331,1780
|
2.2780642718897113,0.14098048384438178,0.64904737623524,-0.15706295482882135,-0.20050904201939973,1.4071872159758687,-1.0007215188288232,-0.42120377836259065,-0.6941314197209414,0.3885005023995106,3.535416449055476,-0.9767075535898113,-0.42120377836259065,2.9093530775549494,-0.2661038286652666,-0.24418159668346107,0.014520145426408674,-1.0007215188288232,1.0358164604588085,1.1674604442373642,-0.6941314197209414,-0.8577339369682366,-0.7638342514312623,-0.9527674967759283,0.7081153372030551,-0.09231141282339332,-0.6250309026232277,-0.09231141282339332,0.4290838414759394,0.7277194848631139,0.014520145426408674,0.9214825561524033,-0.2661038286652666,-0.7872049149016607,0.2449677445585254,-0.7872049149016607,-0.2661038286652666,0.12003241207649194,-0.48858049757519073,0.6094532176877998,0.4694822353754309,0.03572669165067375,0.14098048384438178,0.8444676370207627,-0.09231141282339332,1.2233207047385817,2.143704011138066,-0.006739164246572185,-0.37659150480827835,0.09903334462182867,1.1674604442373642,0.26561689337391103,1.9903992795510101,-0.48858049757519073,-0.28808392260207233,0.40881543685910227,-0.1787578934323262,-0.8106447024352365,-0.04941754059447337,-0.5111634909229179,-0.5338093246549072,1.6054641390302427,-0.740532149740219,-0.3988673947128502,0.64904737623524,-0.6479983733197957,1.4616665228240524,1.0736179845718188,-1.0489737282202127,-0.332219403312167,0.9022890486166665,-0.5338093246549072,-0.7872049149016607,2.4927342354820032,0.3885005023995106,0.20352212550695528,-0.6021287719704128,0.34772985125492284,-0.9767075535898113,0.20352212550695528,0.8057169414204521,-0.09231141282339332,-0.6941314197209414,0.7472814698483077,-0.1138401084971145,-0.15706295482882135,1.443540927049774,-0.31012230394858126,0.6687795395939293,0.14098048384438178,-2.547439296229894,-0.13542382527329797,-0.04941754059447337,-0.09231141282339332,2.0758547589474974,0.9022890486166665,0.6687795395939293,-0.48858049757519073,-0.46605986346971,-0.1138401084971145
| 3,210
|
Abnormal blood potassium concentration
| 9
| 13
| 2.161232
| 0.030677
|
P40818,P05023,O00170,Q08426,Q9UNF1,P04075,Q01968,P04637,P04150
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
877,734,72,80,932,966,917,466,465
|
72,966,465,466,734,877,917,80,1504,1233,1368,1087,932
|
2.2780642718897113,0.34772985125492284,0.8057169414204521,0.8057169414204521,0.5297381122387874,0.40881543685910227,0.3885005023995106,2.2111044701538995,0.014520145426408674,0.18272500423106916,0.09903334462182867,0.286217363258279,0.3885005023995106
| 3,210
|
Protein targeting to membrane
| 7
| 35
| 2.15413
| 0.03123
|
O60725,O43681,P09132,P46379,Q15629,P43307,Q9NT62
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
40,104,177,214,22,86,61
|
1125,2546,1414,104,531,40,1785,2308,177,2023,1699,1532,239,86,214,720,1103,880,3104,1882,2960,1886,2259,22,3128,2969,427,1440,1446,61,1310,1032,544,649,1091
|
0.2449677445585254,-0.6479983733197957,0.05688083594047554,1.9387760747315386,0.7277194848631139,2.8463083615822415,-0.13542382527329797,-0.46605986346971,1.4616665228240524,-0.2661038286652666,-0.09231141282339332,-0.006739164246572185,1.2233207047385817,2.143704011138066,1.297292869739083,0.5497334133991656,0.26561689337391103,0.40881543685910227,-1.73245439296629,-0.1787578934323262,-1.146393653735946,-0.1787578934323262,-0.42120377836259065,3.3407208935166444,-1.8934020128115538,-1.1709433084847787,0.8637818220779606,0.05688083594047554,0.05688083594047554,2.3611563581788624,0.14098048384438178,0.32727353035340734,0.7277194848631139,0.6292720233130275,0.286217363258279
| 3,210
|
Substantia nigra development
| 7
| 17
| 2.148758
| 0.031654
|
P60953,P61586,P14854,P12277,Q8IXJ6,Q04917,P63167
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
574,193,229,588,211,225,224
|
610,1487,2079,2082,1696,588,229,1318,1459,574,193,2115,224,2884,225,1196,211
|
0.64904737623524,0.014520145426408674,-0.31012230394858126,-0.31012230394858126,-0.09231141282339332,0.6687795395939293,1.2603787307732723,0.12003241207649194,0.03572669165067375,0.6884687739263295,1.4071872159758687,-0.332219403312167,1.278853689347875,-1.0007215188288232,1.278853689347875,0.20352212550695528,1.3156964634073816
| 3,210
|
Abnormal left ventricle morphology
| 10
| 28
| 2.143848
| 0.032045
|
O43684,Q15233,P12235,O00170,P40939,O75787,P78536,P00403,P03886,P31040
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
585,485,467,72,170,495,248,334,152,435
|
72,585,1452,903,495,1097,334,152,2764,1695,467,1418,1317,435,170,2481,248,663,1985,1928,485,1625,2671,2286,1804,839,1114,1446
|
2.2780642718897113,0.6687795395939293,0.03572669165067375,0.3885005023995106,0.7668015426370355,0.26561689337391103,1.016858162020565,1.6232905049437316,-0.8577339369682366,-0.09231141282339332,0.8057169414204521,0.05688083594047554,0.12003241207649194,0.8444676370207627,1.515840391838553,-0.5792914685282397,1.204737245801071,0.6094532176877998,-0.24418159668346107,-0.20050904201939973,0.7862799512775219,-0.04941754059447337,-0.740532149740219,-0.44360111347426245,-0.13542382527329797,0.44930601055840114,0.26561689337391103,0.05688083594047554
| 3,210
|
HAD superfamily [IPR023214]
| 9
| 19
| 2.139663
| 0.032382
|
Q969T7,P23634,P49902,Q8NFW8,Q9H857,Q5TFE4,P16615,Q9HD20,Q9H0P0
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
97,219,721,102,728,236,397,28,744
|
2515,734,397,1875,219,721,2732,1047,236,102,1205,97,2490,1811,744,987,728,28,1946
|
-0.6250309026232277,0.5297381122387874,0.9214825561524033,-0.1787578934323262,1.278853689347875,0.5497334133991656,-0.8106447024352365,0.30676947108334135,1.2418678008603015,1.9732209802963745,0.20352212550695528,2.0246682647945144,-0.5792914685282397,-0.13542382527329797,0.5297381122387874,0.34772985125492284,0.5497334133991656,3.15792453539255,-0.20050904201939973
| 3,210
|
HAD-like superfamily [IPR036412]
| 9
| 19
| 2.139663
| 0.032382
|
Q969T7,P23634,P49902,Q8NFW8,Q9H857,Q5TFE4,P16615,Q9HD20,Q9H0P0
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
97,219,721,102,728,236,397,28,744
|
2515,734,397,1875,219,721,2732,1047,236,102,1205,97,2490,1811,744,987,728,28,1946
|
-0.6250309026232277,0.5297381122387874,0.9214825561524033,-0.1787578934323262,1.278853689347875,0.5497334133991656,-0.8106447024352365,0.30676947108334135,1.2418678008603015,1.9732209802963745,0.20352212550695528,2.0246682647945144,-0.5792914685282397,-0.13542382527329797,0.5297381122387874,0.34772985125492284,0.5497334133991656,3.15792453539255,-0.20050904201939973
| 3,210
|
WD40 repeat [IPR001680]
| 35
| 79
| 2.134948
| 0.032765
|
Q6IA86,Q9HC35,P63244,Q8TEQ6,P61962,Q13409,Q15334,O43818,Q9NNW5,P62873,Q13347,Q9Y4P3,Q9GZL7,Q04726,Q96J01,P78406,Q9UFC0,O43660,Q9P2S5,Q9Y3F4,O75530,O60508,Q92747,Q96DI7,O15143,Q9HCU5,Q8WWQ0,P35606,P43034,O43684,O43172,Q9NV06,Q12788,A4D1P6,O94979
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
639,131,138,923,271,664,399,151,813,916,417,432,558,674,957,553,706,938,188,847,940,196,71,984,709,599,473,715,590,585,850,490,619,352,612
|
352,709,1737,850,938,585,151,196,999,940,1188,612,715,2381,590,1166,1747,271,2191,916,138,553,674,1662,619,1431,417,664,1296,1394,978,2195,2499,399,2613,639,2486,1712,2643,1716,1717,2158,1475,2063,2987,923,473,71,1807,984,1964,957,2161,1442,1766,1638,1641,1858,2328,558,2781,1271,2329,131,599,813,1724,490,1860,2003,188,706,1374,1943,2301,2075,847,432,2956
|
0.9788254062828049,0.5497334133991656,-0.1138401084971145,0.4290838414759394,0.36813874070508046,0.6687795395939293,1.6232905049437316,1.38895874189827,0.32727353035340734,0.36813874070508046,0.20352212550695528,0.64904737623524,0.5497334133991656,-0.5111634909229179,0.6687795395939293,0.22426959652252174,-0.1138401084971145,1.1674604442373642,-0.37659150480827835,0.3885005023995106,1.6942735085784877,0.7081153372030551,0.5895906935815504,-0.0708373510934119,0.64904737623524,0.05688083594047554,0.8830555478987258,0.6094532176877998,0.14098048384438178,0.07798293576717874,0.34772985125492284,-0.37659150480827835,-0.6021287719704128,0.9214825561524033,-0.6941314197209414,0.6292720233130275,-0.5792914685282397,-0.09231141282339332,-0.7172980550040869,-0.09231141282339332,-0.09231141282339332,-0.3543756565400391,0.03572669165067375,-0.28808392260207233,-1.195572223965075,0.3885005023995106,0.8057169414204521,2.2947363001504293,-0.13542382527329797,0.34772985125492284,-0.22231680626932795,0.36813874070508046,-0.3543756565400391,0.05688083594047554,-0.1138401084971145,-0.04941754059447337,-0.04941754059447337,-0.15706295482882135,-0.46605986346971,0.7081153372030551,-0.8577339369682366,0.16187790183882575,-0.46605986346971,1.747176663755568,0.6687795395939293,0.4694822353754309,-0.09231141282339332,0.7862799512775219,-0.15706295482882135,-0.24418159668346107,1.4253812176403144,0.5696841825408305,0.09903334462182867,-0.20050904201939973,-0.44360111347426245,-0.28808392260207233,0.44930601055840114,0.8637818220779606,-1.121922556458858
| 3,210
|
Autophagy of mitochondrion
| 15
| 37
| 2.126741
| 0.033442
|
Q14457,P12235,P27544,A6NDU8,P04062,O95352,Q7KZI7,Q9NQ88,P21796,P52789,Q13501,P04637,P30536,Q16543,Q9NT62
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
419,467,296,379,325,354,518,376,19,210,438,466,91,348,61
|
379,1313,3094,2658,354,325,466,2180,467,1419,19,296,91,771,1009,572,1166,210,2574,2959,438,859,419,348,2900,518,1112,1714,1510,2675,2976,1026,376,61,993,2542,933
|
0.9406363002425452,0.12003241207649194,-1.65331482085283,-0.740532149740219,0.9788254062828049,1.0358164604588085,0.8057169414204521,-0.37659150480827835,0.8057169414204521,0.05688083594047554,3.565072073980479,1.1112675033149844,2.092859600557418,0.4896128041999829,0.32727353035340734,0.6884687739263295,0.22426959652252174,1.3156964634073816,-0.6710317035777431,-1.146393653735946,0.8444676370207627,0.4290838414759394,0.8830555478987258,0.9978612170400448,-1.0248100286459398,0.7472814698483077,0.26561689337391103,-0.09231141282339332,0.014520145426408674,-0.740532149740219,-1.1709433084847787,0.32727353035340734,0.9597505084681618,2.3611563581788624,0.34772985125492284,-0.6250309026232277,0.3885005023995106
| 3,210
|
Exercise intolerance
| 10
| 36
| 2.12358
| 0.033705
|
Q9H2D1,Q9Y285,Q8NI60,P40939,P00558,P23786,P00403,P03886,P31040,P06753
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,195,428,170,355,312,334,152,435,283
|
1978,334,355,152,283,750,467,1418,312,1579,3019,435,2140,170,855,617,2481,1985,858,2820,1989,1715,1548,428,2504,1114,1814,1,1775,1859,2789,195,651,2655,2724,1183
|
-0.24418159668346107,1.016858162020565,0.9788254062828049,1.6232905049437316,1.1300357877506997,0.5096980023516975,0.8057169414204521,0.05688083594047554,1.0736179845718188,-0.028051602989249587,-1.2948949262443985,0.8444676370207627,-0.3543756565400391,1.515840391838553,0.4290838414759394,0.64904737623524,-0.5792914685282397,-0.24418159668346107,0.4290838414759394,-0.9051066078988986,-0.24418159668346107,-0.09231141282339332,-0.006739164246572185,0.8637818220779606,-0.6021287719704128,0.26561689337391103,-0.13542382527329797,5.424065052068769,-0.1138401084971145,-0.15706295482882135,-0.8577339369682366,1.4071872159758687,0.6292720233130275,-0.7172980550040869,-0.7872049149016607,0.22426959652252174
| 3,210
|
Initiation of nuclear envelope ne reformation
| 7
| 18
| 2.109086
| 0.034937
|
Q86Y07,P50402,Q8IXJ6,P42166,Q14739,O95067,Q86XL3
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
520,268,211,85,315,409,31
|
1000,409,2881,632,1131,2310,2022,85,1533,268,315,1589,31,520,211,782,1554,2374
|
0.32727353035340734,0.9022890486166665,-1.0007215188288232,0.6292720233130275,0.2449677445585254,-0.46605986346971,-0.2661038286652666,2.143704011138066,-0.006739164246572185,1.1674604442373642,1.0736179845718188,-0.028051602989249587,2.987644251860881,0.7472814698483077,1.3156964634073816,0.4896128041999829,-0.006739164246572185,-0.48858049757519073
| 3,210
|
Selective autophagy
| 8
| 27
| 2.104312
| 0.035351
|
Q9NS69,Q8N4H5,P21796,P67870,O94826,Q13501,Q8IWA4,P63167
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
6,402,19,303,587,438,640,224
|
2012,1782,587,2658,1222,1654,1576,2629,1419,19,1103,1881,2349,224,303,1388,664,438,2427,860,640,402,2098,2675,2409,6,1153
|
-0.2661038286652666,-0.13542382527329797,0.6687795395939293,-0.740532149740219,0.18272500423106916,-0.0708373510934119,-0.028051602989249587,-0.7172980550040869,0.05688083594047554,3.565072073980479,0.26561689337391103,-0.1787578934323262,-0.48858049757519073,1.278853689347875,1.092461638717988,0.07798293576717874,0.6094532176877998,0.8444676370207627,-0.5338093246549072,0.4290838414759394,0.6292720233130275,0.9214825561524033,-0.31012230394858126,-0.740532149740219,-0.5111634909229179,4.959044238463191,0.2449677445585254
| 3,210
|
Carbohydrate derivative transport
| 9
| 17
| 2.102312
| 0.035526
|
Q8TB61,O00400,Q8WTV0,P07602,P12235,L0R6Q1,Q99808,Q96AA3,Q9NZJ7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
163,43,181,335,467,652,156,524,686
|
652,43,1867,2134,2180,335,467,2686,1700,1042,2671,163,181,524,156,746,686
|
0.6094532176877998,2.687053265961324,-0.1787578934323262,-0.3543756565400391,-0.37659150480827835,1.016858162020565,0.8057169414204521,-0.7638342514312623,-0.09231141282339332,0.30676947108334135,-0.740532149740219,1.5517889434452048,1.4616665228240524,0.7472814698483077,1.6054641390302427,0.5297381122387874,0.5895906935815504
| 3,210
|
Calcium signaling pathway
| 7
| 17
| 2.094483
| 0.036217
|
P23634,Q9Y277,P21796,P16615,P45880,Q08752,P12235
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
219,506,19,397,52,372,467
|
2180,467,2686,397,2896,1160,1875,19,219,52,855,372,1986,1142,2395,544,506
|
-0.37659150480827835,0.8057169414204521,-0.7638342514312623,0.9214825561524033,-1.0248100286459398,0.22426959652252174,-0.1787578934323262,3.565072073980479,1.278853689347875,2.509065367944047,0.4290838414759394,0.9597505084681618,-0.24418159668346107,0.2449677445585254,-0.5111634909229179,0.7277194848631139,0.7668015426370355
| 3,210
|
Endoplasmic reticulum organization
| 21
| 47
| 2.085674
| 0.037008
|
Q8N5M9,P49257,Q15629,Q96HR9,Q15006,O43765,Q8N4V1,P57088,Q8NHH9,O43402,Q12981,O95197,Q9NQC3,P46379,Q9P2W9,Q9H2M9,Q6NUK4,O43681,O94979,O15027,Q96A33
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
126,773,22,810,802,531,168,672,175,423,576,68,82,214,228,745,738,104,612,610,375
|
1947,2107,1313,1915,785,610,423,104,531,612,68,2793,214,773,1103,672,1794,2960,1231,1465,576,802,2284,3079,22,1172,2669,1235,738,3128,168,126,2457,175,375,810,2620,1998,2068,745,1556,2540,991,82,1646,2678,228
|
-0.22231680626932795,-0.332219403312167,0.12003241207649194,-0.20050904201939973,0.4694822353754309,0.64904737623524,0.8637818220779606,1.9387760747315386,0.7277194848631139,0.64904737623524,2.311381403119757,-0.8813845471104144,1.297292869739083,0.4896128041999829,0.26561689337391103,0.5895906935815504,-0.13542382527329797,-1.146393653735946,0.18272500423106916,0.03572669165067375,0.6884687739263295,0.4694822353754309,-0.44360111347426245,-1.5491193478204588,3.3407208935166444,0.22426959652252174,-0.740532149740219,0.18272500423106916,0.5297381122387874,-1.8934020128115538,1.5338312891339945,1.7647482499836686,-0.556518486029154,1.4797581820627799,0.9597505084681618,0.4694822353754309,-0.6941314197209414,-0.24418159668346107,-0.28808392260207233,0.5297381122387874,-0.006739164246572185,-0.6250309026232277,0.34772985125492284,2.1942959806671287,-0.04941754059447337,-0.740532149740219,1.278853689347875
| 3,210
|
Negative regulation of reactive oxygen species metabolic process
| 6
| 13
| 2.081772
| 0.037363
|
P61586,Q14457,Q8IXJ6,Q9NQ88,P52789,O75027
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
193,419,211,376,210,333
|
333,466,1696,1700,1620,210,193,2393,419,211,2675,376,2785
|
1.016858162020565,0.8057169414204521,-0.09231141282339332,-0.09231141282339332,-0.04941754059447337,1.3156964634073816,1.4071872159758687,-0.5111634909229179,0.8830555478987258,1.3156964634073816,-0.740532149740219,0.9597505084681618,-0.8577339369682366
| 3,210
|
Subsets and Splits
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