term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Steroid biosynthetic process
| 12
| 44
| 2.081344
| 0.037402
|
Q15392,Q14534,O75845,Q9UHI6,Q9H3P7,Q16850,Q13510,Q15800,P16435,Q14739,P15121,P30536
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
100,255,293,331,306,140,304,54,153,315,371,91
|
1095,1612,293,1917,2942,396,734,1696,1697,371,153,944,634,1786,1422,91,2572,2420,2186,1323,2694,2426,304,577,255,315,2911,100,1711,1846,2718,54,140,1988,2700,2585,1935,2916,2754,2242,2564,306,1215,331
|
0.26561689337391103,-0.04941754059447337,1.1112675033149844,-0.20050904201939973,-1.121922556458858,0.9214825561524033,0.5297381122387874,-0.09231141282339332,-0.09231141282339332,0.9597505084681618,1.6232905049437316,0.36813874070508046,0.6292720233130275,-0.13542382527329797,0.05688083594047554,2.092859600557418,-0.6710317035777431,-0.5338093246549072,-0.37659150480827835,0.12003241207649194,-0.7638342514312623,-0.5338093246549072,1.092461638717988,0.6884687739263295,1.1861172256824857,1.0736179845718188,-1.0489737282202127,2.0075483284887525,-0.09231141282339332,-0.15706295482882135,-0.7872049149016607,2.4927342354820032,1.6765758036559943,-0.24418159668346107,-0.7638342514312623,-0.6710317035777431,-0.20050904201939973,-1.0489737282202127,-0.8341541839153083,-0.3988673947128502,-0.6479983733197957,1.092461638717988,0.20352212550695528,1.0358164604588085
| 3,210
|
Reactive oxygen species metabolic process
| 13
| 43
| 2.067046
| 0.03873
|
Q9P0J0,P61586,Q14457,P42785,Q9BSK2,Q8IXJ6,Q9NQ88,Q16539,P52789,P00403,O75027,P30536,Q15067
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,193,419,133,9,211,376,339,210,334,333,91,60
|
333,1487,733,334,3108,466,1831,2111,1696,3164,2379,3117,908,2744,91,1617,1700,1620,133,3048,210,2690,193,1502,636,1429,2393,1797,1504,1799,419,60,2151,339,2456,211,2649,2675,9,376,2785,33,2542
|
1.016858162020565,0.014520145426408674,0.5297381122387874,1.016858162020565,-1.7590285248459558,0.8057169414204521,-0.15706295482882135,-0.332219403312167,-0.09231141282339332,-2.283970793139223,-0.5111634909229179,-1.8124742250552148,0.3885005023995106,-0.8341541839153083,2.092859600557418,-0.04941754059447337,-0.09231141282339332,-0.04941754059447337,1.7295737816840555,-1.42092054737106,1.3156964634073816,-0.7638342514312623,1.4071872159758687,0.014520145426408674,0.6292720233130275,0.05688083594047554,-0.5111634909229179,-0.13542382527329797,0.014520145426408674,-0.13542382527329797,0.8830555478987258,2.410693261639707,-0.3543756565400391,1.016858162020565,-0.556518486029154,1.3156964634073816,-0.7172980550040869,-0.740532149740219,4.268651553761713,0.9597505084681618,-0.8577339369682366,2.956395767747345,-0.6250309026232277
| 3,210
|
Nucleophile aminohydrolases, N-terminal [IPR029055]
| 7
| 17
| 2.063666
| 0.039049
|
Q06203,P28072,P60900,Q06210,P08243,P20618,P49721
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
383,452,552,173,116,469,186
|
1866,116,469,1353,2312,1615,2216,696,1460,452,907,2085,186,552,383,173,1025
|
-0.1787578934323262,1.8172767653783097,0.8057169414204521,0.09903334462182867,-0.46605986346971,-0.04941754059447337,-0.3988673947128502,0.5696841825408305,0.03572669165067375,0.8251127563510817,0.3885005023995106,-0.31012230394858126,1.4253812176403144,0.7081153372030551,0.9406363002425452,1.4797581820627799,0.32727353035340734
| 3,210
|
Secondary alcohol metabolic process
| 15
| 42
| 2.063211
| 0.039093
|
Q9BQE5,Q15392,Q14534,O75845,Q14739,P04062,O15118,Q16850,P35610,P04035,Q8WTV0,Q9NWW5,P16435,Q15800,Q13907
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,100,255,293,315,325,493,140,83,396,181,543,153,54,577
|
493,1155,1612,293,1037,1917,2942,3165,396,325,2377,1696,1697,153,1786,83,2572,2420,2186,571,2219,2220,1323,1042,2529,2694,2426,577,255,315,2911,100,2718,54,140,1932,181,1936,2,543,1215,3191
|
0.7668015426370355,0.22426959652252174,-0.04941754059447337,1.1112675033149844,0.30676947108334135,-0.20050904201939973,-1.121922556458858,-2.3127380978900742,0.9214825561524033,1.0358164604588085,-0.5111634909229179,-0.09231141282339332,-0.09231141282339332,1.6232905049437316,-0.13542382527329797,2.1774598255807205,-0.6710317035777431,-0.5338093246549072,-0.37659150480827835,0.6884687739263295,-0.3988673947128502,-0.3988673947128502,0.12003241207649194,0.30676947108334135,-0.6250309026232277,-0.7638342514312623,-0.5338093246549072,0.6884687739263295,1.1861172256824857,1.0736179845718188,-1.0489737282202127,2.0075483284887525,-0.7872049149016607,2.4927342354820032,1.6765758036559943,-0.20050904201939973,1.4616665228240524,-0.20050904201939973,5.245263938346782,0.7277194848631139,0.20352212550695528,-2.979687247173523
| 3,210
|
Ion transmembrane transport
| 42
| 151
| 2.060881
| 0.039314
|
Q9H2D1,Q9UHG3,P33527,P53985,Q15334,P21796,O75844,Q14847,P16615,Q9UHD1,O00299,Q9HD20,Q8TB61,Q9HC07,Q8N4V1,O00400,Q9UBX3,Q6P4A7,P45880,Q70HW3,Q9Y619,P30405,O43772,O75964,Q9UDW1,Q96NB2,P00403,O75027,P12235,Q04917,P31930,P23634,P14854,O75947,O60831,Q8N1S5,Q9Y277,P08183,Q8IUH4,P20674,P13073,P27695
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,14,267,145,399,19,20,279,397,544,275,28,163,560,168,43,50,440,52,55,59,434,66,67,75,526,334,333,467,225,220,219,229,479,478,112,506,113,374,498,370,246
|
275,43,2657,565,1867,1035,66,2134,1036,1976,478,333,999,1416,1977,2050,20,2627,479,67,2016,2052,334,734,2416,2377,2180,2553,2993,2212,1038,1693,2274,113,2080,823,3142,1873,1696,467,2686,370,229,397,2896,1160,1875,498,2339,3160,1457,19,219,1318,3037,246,1421,434,792,2083,220,267,793,2343,2571,2084,771,52,1383,2923,2383,3113,2114,3048,2445,145,2714,1358,1658,1841,1500,1622,2960,2115,2256,799,2732,887,775,225,554,2193,3011,1886,3166,1504,1799,1142,620,2395,801,279,399,1048,440,1398,55,1237,374,1509,2699,112,168,1330,163,2988,2360,2809,526,2675,2976,2066,1937,3031,1251,2902,1814,1,1772,1087,1941,1969,560,746,28,2919,50,75,544,14,1563,2877,2624,2169,506,1276,1091,1278,59,1688,2760
|
1.1487666995177788,2.687053265961324,-0.740532149740219,0.6884687739263295,-0.1787578934323262,0.30676947108334135,2.311381403119757,-0.3543756565400391,0.30676947108334135,-0.24418159668346107,0.7862799512775219,1.016858162020565,0.32727353035340734,0.05688083594047554,-0.24418159668346107,-0.28808392260207233,3.535416449055476,-0.7172980550040869,0.7862799512775219,2.311381403119757,-0.2661038286652666,-0.28808392260207233,1.016858162020565,0.5297381122387874,-0.5338093246549072,-0.5111634909229179,-0.37659150480827835,-0.6479983733197957,-1.2202811138168626,-0.3988673947128502,0.30676947108334135,-0.09231141282339332,-0.44360111347426245,1.8521420832959734,-0.31012230394858126,0.44930601055840114,-2.030379226705189,-0.1787578934323262,-0.09231141282339332,0.8057169414204521,-0.7638342514312623,0.9597505084681618,1.2603787307732723,0.9214825561524033,-1.0248100286459398,0.22426959652252174,-0.1787578934323262,0.7668015426370355,-0.48858049757519073,-2.2268000244687314,0.03572669165067375,3.565072073980479,1.278853689347875,0.12003241207649194,-1.3702552416869775,1.204737245801071,0.05688083594047554,0.8444676370207627,0.4694822353754309,-0.31012230394858126,1.278853689347875,1.1674604442373642,0.4694822353754309,-0.48858049757519073,-0.6710317035777431,-0.31012230394858126,0.4896128041999829,2.509065367944047,0.07798293576717874,-1.0732132719357752,-0.5111634909229179,-1.785701460422968,-0.332219403312167,-1.42092054737106,-0.556518486029154,1.6588461750842975,-0.7872049149016607,0.09903334462182867,-0.0708373510934119,-0.15706295482882135,0.014520145426408674,-0.04941754059447337,-1.146393653735946,-0.332219403312167,-0.42120377836259065,0.4694822353754309,-0.8106447024352365,0.40881543685910227,0.4896128041999829,1.278853689347875,0.7081153372030551,-0.37659150480827835,-1.2699417243874822,-0.1787578934323262,-2.3706437779017397,0.014520145426408674,-0.13542382527329797,0.2449677445585254,0.64904737623524,-0.5111634909229179,0.4694822353754309,1.1487666995177788,0.9214825561524033,0.30676947108334135,0.8444676370207627,0.07798293576717874,2.4599952437757544,0.18272500423106916,0.9597505084681618,0.014520145426408674,-0.7638342514312623,1.8695290813707817,1.5338312891339945,0.12003241207649194,1.5517889434452048,-1.195572223965075,-0.48858049757519073,-0.8813845471104144,0.7472814698483077,-0.740532149740219,-1.1709433084847787,-0.28808392260207233,-0.20050904201939973,-1.3199310652066065,0.18272500423106916,-1.0248100286459398,-0.13542382527329797,5.424065052068769,-0.1138401084971145,0.286217363258279,-0.20050904201939973,-0.22231680626932795,0.7081153372030551,0.5297381122387874,3.15792453539255,-1.0489737282202127,2.557906632557138,2.2613651972231907,0.7277194848631139,3.886275851199562,-0.006739164246572185,-0.9767075535898113,-0.6941314197209414,-0.3543756565400391,0.7668015426370355,0.16187790183882575,0.286217363258279,0.16187790183882575,2.4435871616487934,-0.0708373510934119,-0.8341541839153083
| 3,210
|
Outer membrane
| 12
| 92
| 2.056655
| 0.039719
|
Q8N2A8,Q9NQZ5,Q9NS69,Q9NZ45,P09601,O43169,Q8WY22,P21796,P45880,O00264,P30536,Q9Y6C9
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
130,165,6,137,169,74,81,19,52,115,91,29
|
115,1313,3188,74,1611,710,903,587,2658,1530,1222,2942,2742,2082,169,851,1493,19,91,1136,3038,1702,2606,52,268,912,210,2481,1659,593,2193,2608,2282,555,2118,860,777,2285,1989,2577,804,2986,1020,2900,1080,2200,640,760,1632,1203,130,402,1510,837,2873,2357,838,1720,81,1053,2989,1405,2587,1764,2976,2539,1336,682,3031,1026,2242,527,1272,376,165,6,1972,1308,2436,2863,1819,1646,137,686,730,1215,2876,1372,506,2172,872,29
|
1.8172767653783097,0.12003241207649194,-2.9478173975442443,2.2613651972231907,-0.04941754059447337,0.5497334133991656,0.3885005023995106,0.6687795395939293,-0.740532149740219,-0.006739164246572185,0.18272500423106916,-1.121922556458858,-0.8341541839153083,-0.31012230394858126,1.515840391838553,0.4290838414759394,0.014520145426408674,3.565072073980479,2.092859600557418,0.2449677445585254,-1.3702552416869775,-0.09231141282339332,-0.6941314197209414,2.509065367944047,1.1674604442373642,0.3885005023995106,1.3156964634073816,-0.5792914685282397,-0.0708373510934119,0.6687795395939293,-0.37659150480827835,-0.6941314197209414,-0.44360111347426245,0.7081153372030551,-0.332219403312167,0.4290838414759394,0.4896128041999829,-0.44360111347426245,-0.24418159668346107,-0.6710317035777431,0.4694822353754309,-1.195572223965075,0.32727353035340734,-1.0248100286459398,0.286217363258279,-0.37659150480827835,0.6292720233130275,0.5096980023516975,-0.04941754059447337,0.20352212550695528,1.747176663755568,0.9214825561524033,0.014520145426408674,0.44930601055840114,-0.9767075535898113,-0.48858049757519073,0.44930601055840114,-0.09231141282339332,2.1942959806671287,0.30676947108334135,-1.195572223965075,0.07798293576717874,-0.6710317035777431,-0.1138401084971145,-1.1709433084847787,-0.6250309026232277,0.12003241207649194,0.5895906935815504,-1.3199310652066065,0.32727353035340734,-0.3988673947128502,0.7472814698483077,0.16187790183882575,0.9597505084681618,1.5517889434452048,4.959044238463191,-0.22231680626932795,0.14098048384438178,-0.5338093246549072,-0.9527674967759283,-0.13542382527329797,-0.04941754059447337,1.7119394487268482,0.5895906935815504,0.5497334133991656,0.20352212550695528,-0.9767075535898113,0.09903334462182867,0.7668015426370355,-0.3543756565400391,0.4290838414759394,3.065374122452209
| 3,210
|
Cellular response to molecule of bacterial origin
| 7
| 27
| 2.045174
| 0.040838
|
P61586,P09429,P11802,Q8IXJ6,Q16539,Q8WTV0,P30536
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
193,234,144,211,339,181,91
|
939,1693,1576,234,144,735,1068,381,2056,635,91,1617,193,339,3041,1544,806,2037,2403,211,2157,181,1722,1763,1059,2739,2075
|
0.36813874070508046,-0.09231141282339332,-0.028051602989249587,1.2418678008603015,1.6588461750842975,0.5297381122387874,0.286217363258279,0.9406363002425452,-0.28808392260207233,0.6292720233130275,2.092859600557418,-0.04941754059447337,1.4071872159758687,1.016858162020565,-1.3702552416869775,-0.006739164246572185,0.4694822353754309,-0.2661038286652666,-0.5111634909229179,1.3156964634073816,-0.3543756565400391,1.4616665228240524,-0.09231141282339332,-0.1138401084971145,0.30676947108334135,-0.8106447024352365,-0.28808392260207233
| 3,210
|
Mitochondrial membrane organization
| 15
| 48
| 2.03169
| 0.042185
|
Q9Y5J9,Q9P0J0,Q13505,P49840,Q8IWA4,Q9NS69,Q9Y584,Q15070,P45880,P52789,O94826,P12235,P04637,P49841,P30405
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
529,33,555,572,640,6,13,45,52,210,587,467,466,592,434
|
2332,848,1611,903,587,2658,2016,466,2180,1654,2082,467,434,2898,1356,3038,2420,52,1191,572,592,1103,210,2193,555,45,2285,1047,1989,804,1020,640,760,1632,3080,2988,682,869,6,2436,1819,33,2542,2789,1278,872,13,529
|
-0.48858049757519073,0.4290838414759394,-0.04941754059447337,0.3885005023995106,0.6687795395939293,-0.740532149740219,-0.2661038286652666,0.8057169414204521,-0.37659150480827835,-0.0708373510934119,-0.31012230394858126,0.8057169414204521,0.8444676370207627,-1.0248100286459398,0.09903334462182867,-1.3702552416869775,-0.5338093246549072,2.509065367944047,0.20352212550695528,0.6884687739263295,0.6687795395939293,0.26561689337391103,1.3156964634073816,-0.37659150480827835,0.7081153372030551,2.6065219729812474,-0.44360111347426245,0.30676947108334135,-0.24418159668346107,0.4694822353754309,0.32727353035340734,0.6292720233130275,0.5096980023516975,-0.04941754059447337,-1.5491193478204588,-1.195572223965075,0.5895906935815504,0.4290838414759394,4.959044238463191,-0.5338093246549072,-0.13542382527329797,2.956395767747345,-0.6250309026232277,-0.8577339369682366,0.16187790183882575,0.4290838414759394,3.915034698124895,0.7472814698483077
| 3,210
|
Natural killer cell mediated cytotoxicity
| 7
| 14
| 2.02902
| 0.042456
|
P10321,P28482,P63000,P04439,Q06124,Q9UHD1,P42574
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
320,635,636,449,663,544,717
|
789,449,320,1874,1160,2056,635,717,1165,1502,636,1623,663,544
|
0.4694822353754309,0.8251127563510817,1.0547363295691754,-0.1787578934323262,0.22426959652252174,-0.28808392260207233,0.6292720233130275,0.5497334133991656,0.22426959652252174,0.014520145426408674,0.6292720233130275,-0.04941754059447337,0.6094532176877998,0.7277194848631139
| 3,210
|
Hypokalemia
| 7
| 9
| 2.019043
| 0.043483
|
P40818,P05023,O00170,Q08426,Q9UNF1,P04637,P04150
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
877,734,72,80,932,466,465
|
72,465,466,734,877,917,80,1368,932
|
2.2780642718897113,0.8057169414204521,0.8057169414204521,0.5297381122387874,0.40881543685910227,0.3885005023995106,2.2111044701538995,0.09903334462182867,0.3885005023995106
| 3,210
|
Tetratricopeptide repeat [IPR019734]
| 18
| 48
| 2.005726
| 0.044885
|
O43765,Q99614,Q6PGP7,Q15785,Q13451,O00170,Q9BXJ9,Q6P3X3,Q6DKK2,Q07866,P31948,Q9Y6X3,Q6P2P2,Q6PD62,O94826,Q08752,Q15006,Q9UJX4
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
531,488,38,777,857,72,557,273,439,359,109,406,281,806,587,372,802,846
|
1094,72,1186,531,1785,587,1692,1003,1577,1461,109,2026,1425,1103,2347,1624,359,372,2320,2452,2556,857,2428,802,777,439,281,273,806,38,1899,2752,2038,1150,488,1115,557,1270,1368,2205,989,2654,1275,846,899,2266,1564,406
|
0.26561689337391103,2.2780642718897113,0.20352212550695528,0.7277194848631139,-0.13542382527329797,0.6687795395939293,-0.09231141282339332,0.32727353035340734,-0.028051602989249587,0.03572669165067375,1.8868858346923807,-0.2661038286652666,0.05688083594047554,0.26561689337391103,-0.48858049757519073,-0.04941754059447337,0.9788254062828049,0.9597505084681618,-0.46605986346971,-0.556518486029154,-0.6479983733197957,0.4290838414759394,-0.5338093246549072,0.4694822353754309,0.4896128041999829,0.8444676370207627,1.1487666995177788,1.1674604442373642,0.4694822353754309,2.8936264910222325,-0.1787578934323262,-0.8341541839153083,-0.2661038286652666,0.2449677445585254,0.7862799512775219,0.26561689337391103,0.7081153372030551,0.16187790183882575,0.09903334462182867,-0.37659150480827835,0.34772985125492284,-0.7172980550040869,0.16187790183882575,0.44930601055840114,0.40881543685910227,-0.42120377836259065,-0.006739164246572185,0.9214825561524033
| 3,210
|
Porphyrin containing compound metabolic process
| 7
| 19
| 2.001932
| 0.045292
|
P22830,P09601,P33527,O00264,O75027,P30519,P30536
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,169,267,115,333,25,91
|
115,333,2600,2569,169,96,1787,25,91,267,382,1357,796,1757,1237,1524,3183,3042,2542
|
1.8172767653783097,1.016858162020565,-0.6941314197209414,-0.6710317035777431,1.515840391838553,2.0246682647945144,-0.13542382527329797,3.2649229530203527,2.092859600557418,1.1674604442373642,0.9406363002425452,0.09903334462182867,0.4694822353754309,-0.1138401084971145,0.18272500423106916,0.014520145426408674,-2.7291293249888016,-1.3702552416869775,-0.6250309026232277
| 3,210
|
Sphingolipid metabolism
| 10
| 28
| 1.993356
| 0.046222
|
O95470,P51648,P27544,O43681,Q96G23,Q16739,P04062,O15121,Q13510,Q06136
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
35,101,296,104,172,44,325,108,304,155
|
1947,108,611,1825,104,2793,35,325,2764,3162,335,3179,657,3056,1492,1005,944,296,101,155,304,44,2806,172,1998,1646,686,2678
|
-0.22231680626932795,1.8868858346923807,0.64904737623524,-0.15706295482882135,1.9387760747315386,-0.8813845471104144,2.9093530775549494,1.0358164604588085,-0.8577339369682366,-2.2553252413912954,1.016858162020565,-2.6679987910560428,0.6094532176877998,-1.4463831438360908,0.014520145426408674,0.32727353035340734,0.36813874070508046,1.1112675033149844,1.9903992795510101,1.6054641390302427,1.092461638717988,2.6709959483183634,-0.8813845471104144,1.497816080363346,-0.24418159668346107,-0.04941754059447337,0.5895906935815504,-0.740532149740219
| 3,210
|
Nuclear receptors metapathway
| 15
| 49
| 1.992435
| 0.046323
|
Q14914,Q99735,O00170,P09601,P21266,Q16543,Q15067,P11802,Q08426,Q8N1S5,P08183,Q13501,Q15185,P23786,O00767
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
99,386,72,169,327,348,60,144,80,112,113,438,121,312,189
|
72,189,1867,655,465,632,1654,113,1832,3025,169,851,3185,1696,144,3164,327,634,312,736,1421,2814,2021,1787,3118,1191,1165,912,1139,2387,2193,80,3034,857,438,1752,2773,99,60,121,1471,348,778,3015,112,1115,386,1772,1272
|
2.2780642718897113,1.4071872159758687,-0.1787578934323262,0.6094532176877998,0.8057169414204521,0.6292720233130275,-0.0708373510934119,1.8521420832959734,-0.15706295482882135,-1.3199310652066065,1.515840391838553,0.4290838414759394,-2.82193125538963,-0.09231141282339332,1.6588461750842975,-2.283970793139223,1.0358164604588085,0.6292720233130275,1.0736179845718188,0.5297381122387874,0.05688083594047554,-0.9051066078988986,-0.2661038286652666,-0.13542382527329797,-1.8124742250552148,0.20352212550695528,0.22426959652252174,0.3885005023995106,0.2449677445585254,-0.5111634909229179,-0.37659150480827835,2.2111044701538995,-1.3450509101454364,0.4290838414759394,0.8444676370207627,-0.1138401084971145,-0.8577339369682366,2.0075483284887525,2.410693261639707,1.7997981488475483,0.03572669165067375,0.9978612170400448,0.4896128041999829,-1.2699417243874822,1.8695290813707817,0.26561689337391103,0.9406363002425452,-0.1138401084971145,0.16187790183882575
| 3,210
|
Alzheimers disease
| 23
| 58
| 1.979593
| 0.047749
|
Q9Y6M9,P14406,P28482,P16615,Q9UHD1,O95298,O43676,P31040,P51970,O95299,P22695,Q9UDW1,O14949,O75380,P00403,P49841,O75306,P31930,P14854,O75947,P78536,P13073,P20674
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
530,5,635,397,544,282,41,435,573,690,569,75,76,711,334,592,464,220,229,479,248,370,498
|
996,2657,76,41,1281,1416,464,711,1487,479,282,690,334,1098,2377,2993,1038,823,2685,1873,370,5,1067,229,875,1289,397,1068,2603,498,1317,569,1318,3037,2056,3117,635,435,220,2343,717,2383,3113,1165,1426,592,573,2691,248,1467,2395,2887,2500,2807,2754,75,544,530
|
0.32727353035340734,-0.740532149740219,2.2446389541407687,2.814646690863611,0.14098048384438178,0.05688083594047554,0.8057169414204521,0.5497334133991656,0.014520145426408674,0.7862799512775219,1.1300357877506997,0.5696841825408305,1.016858162020565,0.26561689337391103,-0.5111634909229179,-1.2202811138168626,0.30676947108334135,0.44930601055840114,-0.7638342514312623,-0.1787578934323262,0.9597505084681618,4.972198060062475,0.286217363258279,1.2603787307732723,0.40881543685910227,0.14098048384438178,0.9214825561524033,0.286217363258279,-0.6941314197209414,0.7668015426370355,0.12003241207649194,0.6884687739263295,0.12003241207649194,-1.3702552416869775,-0.28808392260207233,-1.8124742250552148,0.6292720233130275,0.8444676370207627,1.278853689347875,-0.48858049757519073,0.5497334133991656,-0.5111634909229179,-1.785701460422968,0.22426959652252174,0.05688083594047554,0.6687795395939293,0.6884687739263295,-0.7638342514312623,1.204737245801071,0.03572669165067375,-0.5111634909229179,-1.0007215188288232,-0.6021287719704128,-0.8813845471104144,-0.8341541839153083,2.2613651972231907,0.7277194848631139,0.7472814698483077
| 3,210
|
Apoptosis
| 26
| 123
| 1.970541
| 0.048776
|
P63244,Q9Y2I1,Q96A26,P21796,Q9P0J0,P42575,O95470,Q14457,P09601,Q9H2J4,Q13501,P30405,O95197,Q9UDX5,Q9UHX1,Q01085,Q16539,P46379,P04637,P63167,O75940,P52756,Q9NQ88,Q9H8M7,Q08752,Q96KA5
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
138,405,18,19,33,285,35,419,169,182,438,434,68,69,70,328,339,214,466,224,105,235,376,244,372,127
|
2906,747,848,1186,787,3094,3000,1611,1452,2517,507,105,2658,68,35,2017,1742,1575,692,465,1098,466,2377,632,169,2686,1419,19,2743,2056,635,434,1163,1699,717,285,771,214,1791,2384,235,2348,1703,224,138,1538,328,2530,1985,2193,2608,372,1751,576,976,3057,1466,2226,2557,438,1799,1467,1891,2428,419,2750,801,2061,1845,1591,339,1172,595,863,2643,2644,1805,2971,1719,1596,1673,1477,1403,18,1935,2537,2327,2039,2809,985,1853,127,2587,2737,2242,2937,2163,1522,2889,2703,182,869,244,1369,376,1970,1776,2371,1559,686,33,964,69,1686,70,2243,2437,2544,405,2625,2172,901,2247
|
-1.0489737282202127,0.5096980023516975,0.4290838414759394,0.20352212550695528,0.4694822353754309,-1.65331482085283,-1.2450707022746819,-0.04941754059447337,0.03572669165067375,-0.6250309026232277,0.7472814698483077,1.9387760747315386,-0.740532149740219,2.311381403119757,2.9093530775549494,-0.2661038286652666,-0.1138401084971145,-0.028051602989249587,0.5696841825408305,0.8057169414204521,0.26561689337391103,0.8057169414204521,-0.5111634909229179,0.6292720233130275,1.515840391838553,-0.7638342514312623,0.05688083594047554,3.565072073980479,-0.8341541839153083,-0.28808392260207233,0.6292720233130275,0.8444676370207627,0.22426959652252174,-0.09231141282339332,0.5497334133991656,1.1300357877506997,0.4896128041999829,1.297292869739083,-0.13542382527329797,-0.5111634909229179,1.2418678008603015,-0.48858049757519073,-0.09231141282339332,1.278853689347875,1.6942735085784877,-0.006739164246572185,1.0358164604588085,-0.6250309026232277,-0.24418159668346107,-0.37659150480827835,-0.6941314197209414,0.9597505084681618,-0.1138401084971145,0.6884687739263295,0.34772985125492284,-1.4463831438360908,0.03572669165067375,-0.3988673947128502,-0.6479983733197957,0.8444676370207627,-0.13542382527329797,0.03572669165067375,-0.1787578934323262,-0.5338093246549072,0.8830555478987258,-0.8341541839153083,0.4694822353754309,-0.28808392260207233,-0.15706295482882135,-0.028051602989249587,1.016858162020565,0.22426959652252174,0.6687795395939293,0.4290838414759394,-0.7172980550040869,-0.7172980550040869,-0.13542382527329797,-1.1709433084847787,-0.09231141282339332,-0.028051602989249587,-0.0708373510934119,0.03572669165067375,0.07798293576717874,3.7268039481622726,-0.20050904201939973,-0.6250309026232277,-0.46605986346971,-0.2661038286652666,-0.8813845471104144,0.34772985125492284,-0.15706295482882135,1.7647482499836686,-0.6710317035777431,-0.8106447024352365,-0.3988673947128502,-1.0975293235654124,-0.3543756565400391,0.014520145426408674,-1.0007215188288232,-0.7638342514312623,1.4616665228240524,0.4290838414759394,1.2233207047385817,0.09903334462182867,0.9597505084681618,-0.22231680626932795,-0.1138401084971145,-0.48858049757519073,-0.006739164246572185,0.5895906935815504,2.956395767747345,0.36813874070508046,2.311381403119757,-0.0708373510934119,2.311381403119757,-0.3988673947128502,-0.5338093246549072,-0.6250309026232277,0.9214825561524033,-0.6941314197209414,-0.3543756565400391,0.40881543685910227,-0.3988673947128502
| 3,210
|
Antigen processing ubiquitination proteasome degradation
| 28
| 76
| 3.552979
| 0.000381
|
P60900,P49720,O94874,O00231,P55786,Q9H1A4,Q9UJX4,P19474,Q13867,P49427,Q92990,Q15386,A0AVT1,P28070,P28072,Q9UIQ6,P68036,P28074,P49721,Q9C0C9,Q13618,P52888,Q9Y4B6,Q99436,Q15008,Q9UJX3,P20618,O95376
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,255,518,264,26,157,556,29,282,405,437,549,37,38,543,45,427,60,65,469,211,339,229,96,479,512,117,493
|
37,264,1056,1293,1686,541,2155,518,493,1210,29,117,1306,1167,1212,1213,1540,870,38,543,60,1590,1018,2250,1651,1074,405,255,65,799,339,964,26,125,1932,1600,1656,1263,1320,1175,1078,919,427,2228,1603,840,1560,1808,211,282,1610,1713,479,843,2022,549,566,2116,1276,884,1721,437,706,641,96,1097,469,157,45,676,512,556,677,1463,1234,229
|
2.9589633825131183,0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,0.5289862962916688,0.5601572877142909,-0.06607616153332166,3.338926259238387,1.5527533004356622,-0.13661678053279144,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-0.3173625574811562,0.07215573022457085,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.6830652924493599,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.8032451697533327,0.10614213666844603,3.416142107313884,1.474214893902258,-0.5810666157787491,-0.3173625574811562,-0.3542766862538596,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,0.13990709897991843,0.6525998327464225,-0.9789611482255609,-0.3173625574811562,0.20678635338280518,-0.28070290912863155,-0.4665389394864189,1.0926583185496224,0.9208380784964595,-0.3173625574811562,-0.391444589562264,0.5911482301983078,0.20678635338280518,-0.6586680831224061,0.49763272112609636,0.4660939704199051,-0.7769319049938614,-0.10122447507190645,0.17345405363114286,-0.391444589562264,0.6525998327464225,0.3380332804355645,0.40245027954676366,1.757119144304389,0.03794435657742731,0.6219616032562505,1.3677940244677216,2.6420354190598694,0.3703398545461924,0.5601572877142909,0.49763272112609636,0.3703398545461924,-0.20814992181924744,-0.06607616153332166,1.0643882560099536
| 2,468
|
Mitotic g2 g2 m phases
| 22
| 79
| 3.381156
| 0.000722
|
P60900,P49720,Q13885,P30153,O75935,O00231,P30154,Q13561,Q9H6D7,P28070,P14635,Q9BV73,O95684,P28074,P49721,P68371,P24941,Q9BVA1,Q99436,Q15691,P07437,P20618
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,255,384,140,148,264,269,409,36,38,175,184,59,60,65,201,207,344,96,222,216,117
|
264,1056,1293,1686,947,541,2155,148,59,402,950,904,216,905,954,175,1478,1210,117,207,1167,1212,1213,1540,870,38,543,60,140,269,2250,1650,962,1651,1074,255,65,799,964,125,1655,966,1263,1489,1759,1320,1175,1601,1078,1222,1129,919,201,1603,1604,840,1939,409,1560,384,842,503,880,1713,479,598,222,1822,96,1097,1914,644,184,344,36,2396,677,2001,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.10614213666844603,0.49763272112609636,-0.8570082192801957,1.3945857941684383,2.3536390018116236,0.6830652924493599,0.10614213666844603,0.13990709897991843,1.0643882560099536,0.13990709897991843,0.10614213666844603,1.2319049508681916,-0.24429845596012587,-0.06607616153332166,1.5527533004356622,1.0926583185496224,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,1.421252266939875,0.9498475469241873,-1.0201000011979868,-0.3542766862538596,0.10614213666844603,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.3542766862538596,0.10614213666844603,-0.10122447507190645,-0.24429845596012587,-0.4288655702071363,-0.13661678053279144,-0.03116783582721283,-0.3173625574811562,0.03794435657742731,-0.06607616153332166,0.003504403042592986,0.13990709897991843,1.120785882156883,-0.3173625574811562,-0.3173625574811562,0.20678635338280518,-0.5810666157787491,0.6830652924493599,-0.28070290912863155,0.7133603055860006,0.20678635338280518,0.5601572877142909,0.17345405363114286,-0.391444589562264,0.5911482301983078,0.43436739361353727,1.0643882560099536,-0.4665389394864189,1.757119144304389,0.03794435657742731,-0.5426401305377743,0.40245027954676366,1.204330560625009,0.8032451697533327,3.040853068845477,-1.532557517479962,0.3703398545461924,-0.619742816254357,-0.06607616153332166
| 2,468
|
Peptidase activity
| 29
| 90
| 3.374471
| 0.00074
|
P60900,P49720,Q8IYS1,Q5JRX3,O43847,Q4J6C6,Q9NZ08,P55786,Q13867,Q9HB40,P28070,Q9UIQ6,Q93009,Q9NQW7,P50579,P28074,Q9UPU5,P49721,P42575,P42892,P42785,P52888,Q96BN8,Q99436,Q9BYT8,Q9BT78,Q86UV5,Q9H3G5,P20618
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
125,255,274,145,138,151,152,26,282,298,38,45,178,313,50,60,195,65,70,75,209,339,225,96,242,375,371,377,117
|
897,1293,898,489,138,1886,476,359,1690,1246,2205,1065,906,2043,1014,1247,725,117,587,1540,38,543,60,1122,1590,1792,660,1426,626,70,209,75,627,831,255,65,50,799,339,2111,1704,26,125,2372,408,972,282,1269,1562,732,151,1394,145,1668,1332,1140,1087,371,274,1512,849,2417,2271,637,851,1280,178,852,225,1990,1046,96,1627,2193,1948,375,242,1191,377,711,607,298,534,313,1629,152,45,195,1956,1578
|
0.13990709897991843,-0.13661678053279144,0.13990709897991843,0.5601572877142909,1.421252266939875,-0.5426401305377743,0.5911482301983078,0.7434871462800804,-0.391444589562264,-0.10122447507190645,-0.9380658414393885,0.03794435657742731,0.13990709897991843,-0.6978417750235022,0.07215573022457085,-0.10122447507190645,0.3055276524649288,1.5527533004356622,0.43436739361353727,-0.28070290912863155,2.8550887102218057,0.49763272112609636,2.3536390018116236,0.003504403042592986,-0.3173625574811562,-0.4665389394864189,0.3703398545461924,-0.20814992181924744,0.40245027954676366,2.0747334217602056,1.0926583185496224,2.0029346640137495,0.40245027954676366,0.20678635338280518,0.9787054273330804,2.2620942289667187,2.5547286368600663,0.23990727005026555,0.8032451697533327,-0.7769319049938614,-0.391444589562264,3.416142107313884,1.474214893902258,-1.401215472847145,0.6830652924493599,0.10614213666844603,0.9208380784964595,-0.10122447507190645,-0.28070290912863155,0.3055276524649288,1.3945857941684383,-0.1722571888650981,1.421252266939875,-0.3542766862538596,-0.13661678053279144,0.003504403042592986,0.03794435657742731,0.7434871462800804,0.9498475469241873,-0.24429845596012587,0.20678635338280518,-1.7109882266710317,-1.0614818199989162,0.40245027954676366,0.20678635338280518,-0.10122447507190645,1.2319049508681916,0.20678635338280518,1.0643882560099536,-0.619742816254357,0.07215573022457085,1.757119144304389,-0.3173625574811562,-0.8974146674576974,-0.5810666157787491,0.7434871462800804,1.0359739469793032,-0.03116783582721283,0.7434871462800804,0.3380332804355645,0.43436739361353727,0.8916750939887781,0.5289862962916688,0.8623566262060067,-0.3173625574811562,1.3945857941684383,2.6420354190598694,1.1487726610909024,-0.5810666157787491,-0.28070290912863155
| 2,468
|
G2 m checkpoints
| 15
| 74
| 3.176509
| 0.001491
|
P60900,Q8N257,P49721,P49720,Q99436,P28070,P40938,P33991,Q9UQ84,Q14566,P24941,O60921,P14635,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,164,65,255,96,38,220,271,41,272,207,106,175,117,60
|
264,1056,1293,1686,541,2264,106,583,2155,685,950,904,175,1210,117,207,1165,1167,1212,1213,1540,693,762,870,38,543,60,1214,271,910,1592,1966,829,2250,1314,220,1651,1074,255,65,696,661,799,1318,964,125,1656,1263,1489,1320,1175,1601,1078,2379,1492,1131,1603,1497,840,1559,272,1809,1713,479,567,164,927,1513,96,1097,677,1234,41,515
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-1.0614818199989162,1.6302362443481822,0.43436739361353727,-0.8570082192801957,0.3380332804355645,0.10614213666844603,0.13990709897991843,1.2319049508681916,-0.06607616153332166,1.5527533004356622,1.0926583185496224,-0.03116783582721283,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.3380332804355645,0.27281999715468874,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-0.06607616153332166,0.9498475469241873,0.13990709897991843,-0.3173625574811562,-0.619742816254357,0.20678635338280518,-1.0201000011979868,-0.13661678053279144,1.0643882560099536,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.3380332804355645,0.3703398545461924,0.23990727005026555,-0.13661678053279144,0.10614213666844603,1.474214893902258,-0.3542766862538596,-0.10122447507190645,-0.24429845596012587,-0.13661678053279144,-0.03116783582721283,-0.3173625574811562,0.03794435657742731,-1.4447588451088091,-0.24429845596012587,0.003504403042592986,-0.3173625574811562,-0.24429845596012587,0.20678635338280518,-0.28070290912863155,0.9498475469241873,-0.4665389394864189,-0.391444589562264,0.5911482301983078,0.4660939704199051,1.3138288708840293,0.13990709897991843,-0.24429845596012587,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166,2.749470080710629,0.5601572877142909
| 2,468
|
Proteasome, subunit alpha/beta [IPR001353]
| 6
| 14
| 2.977947
| 0.002902
|
P60900,P49721,Q99436,P28070,P20618,P28074
|
Sequence
|
InterPro Family
|
interpro_family
|
125,65,96,38,117,60
|
1686,117,1167,1212,1213,1540,870,38,543,60,255,65,125,96
|
-0.391444589562264,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,0.9787054273330804,2.2620942289667187,1.474214893902258,1.757119144304389
| 2,468
|
Proteasome core complex
| 6
| 14
| 2.977947
| 0.002902
|
P60900,P49721,Q99436,P28070,P20618,P28074
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
125,65,96,38,117,60
|
1686,117,1167,1212,1213,1540,870,38,543,60,255,65,125,96
|
-0.391444589562264,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,0.9787054273330804,2.2620942289667187,1.474214893902258,1.757119144304389
| 2,468
|
Nucleophile aminohydrolases, N-terminal [IPR029055]
| 6
| 17
| 2.942015
| 0.003261
|
P60900,P49721,Q99436,P28070,P20618,P28074
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
125,65,96,38,117,60
|
1686,688,117,1167,1212,1213,1540,870,38,543,60,255,65,125,500,970,96
|
-0.391444589562264,0.3380332804355645,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,0.9787054273330804,2.2620942289667187,1.474214893902258,0.5601572877142909,0.10614213666844603,1.757119144304389
| 2,468
|
Tetratricopeptide-like helical domain superfamily [IPR011990]
| 34
| 71
| 2.908678
| 0.00363
|
Q9Y5A7,P61201,Q02790,Q9BXJ9,Q96EK5,Q32P28,Q6PD62,P49792,Q92552,O75153,O00231,Q9UJX2,Q9UJX4,O15294,Q9Y262,O43242,Q9Y2Z0,O75718,Q00610,Q99747,O00411,Q13451,O15091,Q96BR5,Q15008,Q6PGP7,Q9UBV2,Q9NSK0,Q6ZXV5,Q9UJX3,Q13325,Q9Y5Q9,Q9Y6X3,Q6DKK2
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
396,131,256,532,137,385,528,628,673,19,264,676,556,279,440,541,442,418,564,467,69,597,580,226,479,369,251,111,370,512,119,653,122,126
|
1154,681,264,69,1883,580,279,541,1156,19,418,758,1204,1297,1743,1786,1018,828,1597,1216,1255,628,1317,2017,131,564,256,971,1133,665,1607,1387,119,597,1905,1665,1714,479,1180,1031,385,126,528,369,370,983,673,226,137,989,2029,2384,740,467,532,2146,2089,1192,1729,1350,111,1631,251,676,512,556,440,442,396,653,122
|
-0.03116783582721283,0.3380332804355645,0.9498475469241873,2.0747334217602056,-0.5426401305377743,0.43436739361353727,0.9208380784964595,0.49763272112609636,-0.03116783582721283,3.7891445927352523,0.6525998327464225,0.27281999715468874,-0.06607616153332166,-0.13661678053279144,-0.4288655702071363,-0.4665389394864189,0.07215573022457085,0.20678635338280518,-0.3173625574811562,-0.06607616153332166,-0.10122447507190645,0.40245027954676366,-0.13661678053279144,-0.6586680831224061,1.4477948419810402,0.4660939704199051,0.9787054273330804,0.10614213666844603,0.003504403042592986,0.3703398545461924,-0.3173625574811562,-0.1722571888650981,1.5527533004356622,0.43436739361353727,-0.5426401305377743,-0.3542766862538596,-0.391444589562264,0.5911482301983078,-0.03116783582721283,0.07215573022457085,0.7133603055860006,1.474214893902258,0.5289862962916688,0.7434871462800804,0.7434871462800804,0.10614213666844603,0.3703398545461924,1.0643882560099536,1.4477948419810402,0.10614213666844603,-0.6586680831224061,-1.4447588451088091,0.3055276524649288,0.6219616032562505,0.5289862962916688,-0.8168470964124629,-0.7372632579290869,-0.03116783582721283,-0.391444589562264,-0.13661678053279144,1.6302362443481822,-0.3173625574811562,1.007413609708006,0.3703398545461924,0.5601572877142909,0.49763272112609636,0.6525998327464225,0.6525998327464225,0.7133603055860006,0.40245027954676366,1.5266928073906822
| 2,468
|
Protease
| 22
| 63
| 2.812719
| 0.004912
|
Q5JRX3,O43847,Q4J6C6,Q9NZ08,P55786,Q13867,Q9HB40,Q9UIQ6,Q93009,Q9NQW7,P50579,P28074,Q9UPU5,P42575,P42892,P42785,P52888,Q96BN8,Q99436,Q9BYT8,Q86UV5,Q9H3G5
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
145,138,151,152,26,282,298,45,178,313,50,60,195,70,75,209,339,225,96,242,371,377
|
897,1293,898,138,1886,476,359,2205,1065,906,2043,1014,725,543,60,1122,1590,1426,626,70,209,75,627,831,50,339,2111,1704,26,2372,282,1269,1562,732,151,145,1668,1087,371,1512,2417,851,1280,178,225,1990,1046,96,2193,242,1191,377,711,607,298,534,313,1629,152,45,195,1956,1578
|
0.13990709897991843,-0.13661678053279144,0.13990709897991843,1.421252266939875,-0.5426401305377743,0.5911482301983078,0.7434871462800804,-0.9380658414393885,0.03794435657742731,0.13990709897991843,-0.6978417750235022,0.07215573022457085,0.3055276524649288,0.49763272112609636,2.3536390018116236,0.003504403042592986,-0.3173625574811562,-0.20814992181924744,0.40245027954676366,2.0747334217602056,1.0926583185496224,2.0029346640137495,0.40245027954676366,0.20678635338280518,2.5547286368600663,0.8032451697533327,-0.7769319049938614,-0.391444589562264,3.416142107313884,-1.401215472847145,0.9208380784964595,-0.10122447507190645,-0.28070290912863155,0.3055276524649288,1.3945857941684383,1.421252266939875,-0.3542766862538596,0.03794435657742731,0.7434871462800804,-0.24429845596012587,-1.7109882266710317,0.20678635338280518,-0.10122447507190645,1.2319049508681916,1.0643882560099536,-0.619742816254357,0.07215573022457085,1.757119144304389,-0.8974146674576974,1.0359739469793032,-0.03116783582721283,0.7434871462800804,0.3380332804355645,0.43436739361353727,0.8916750939887781,0.5289862962916688,0.8623566262060067,-0.3173625574811562,1.3945857941684383,2.6420354190598694,1.1487726610909024,-0.5810666157787491,-0.28070290912863155
| 2,468
|
Deubiquitination
| 19
| 72
| 2.801089
| 0.005093
|
P60900,P49720,O00231,P45880,O15294,Q8N257,Q9Y4A5,P28070,Q8NB78,Q9Y3E5,Q93009,P28074,Q9UPU5,P49721,P21796,O14964,Q99436,Q86UV5,P20618
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,255,264,404,279,164,166,38,293,443,178,60,195,65,317,444,96,371,117
|
264,1056,1293,1686,444,279,541,1415,2155,1204,1205,950,904,725,1210,117,317,1167,1212,1213,1540,870,38,543,60,2250,1651,404,627,1074,255,65,1486,799,1704,835,964,1598,125,1263,1550,1320,1175,1078,1603,840,1178,1905,1269,1713,479,1860,371,601,164,293,637,1280,178,1990,96,1097,1627,1460,677,1234,195,1683,999,443,166,1578
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.6219616032562505,0.9208380784964595,0.49763272112609636,-0.20814992181924744,-0.8570082192801957,-0.06607616153332166,-0.06607616153332166,0.10614213666844603,0.13990709897991843,0.3055276524649288,-0.06607616153332166,1.5527533004356622,0.8328806677236555,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.6830652924493599,0.40245027954676366,0.03794435657742731,0.9787054273330804,2.2620942289667187,-0.24429845596012587,0.23990727005026555,-0.391444589562264,0.20678635338280518,0.10614213666844603,-0.3173625574811562,1.474214893902258,-0.10122447507190645,-0.28070290912863155,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.3173625574811562,0.20678635338280518,-0.03116783582721283,-0.5426401305377743,-0.10122447507190645,-0.391444589562264,0.5911482301983078,-0.5044640170129534,0.7434871462800804,0.43436739361353727,1.3138288708840293,0.8916750939887781,0.40245027954676366,-0.10122447507190645,1.2319049508681916,-0.619742816254357,1.757119144304389,0.03794435657742731,-0.3173625574811562,-0.20814992181924744,0.3703398545461924,-0.06607616153332166,1.1487726610909024,-0.3542766862538596,0.10614213666844603,0.6525998327464225,1.3138288708840293,-0.28070290912863155
| 2,468
|
Organelle biogenesis and maintenance
| 24
| 76
| 2.640974
| 0.008267
|
Q92973,A6NIH7,Q13885,P30153,O75935,Q13561,Q10713,P04350,Q9H6D7,Q13505,P78371,Q9BV73,Q9BZK7,P48643,O95684,O00411,P68371,Q9BVA1,Q15691,P07437,Q8IYI6,Q92538,O75964,P54646
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
388,11,384,140,148,409,408,402,36,43,428,184,56,425,59,69,201,344,222,216,239,240,245,363
|
1154,11,69,1579,148,2332,245,59,824,402,904,1011,216,905,1478,1422,1479,1307,2010,140,1374,1072,2265,1650,962,2377,425,2368,912,663,1218,1486,834,363,1127,1655,966,1489,1601,1129,201,428,2268,1975,408,1939,43,409,384,842,503,880,631,598,222,1863,774,1670,1621,480,239,2383,1448,240,388,466,644,184,344,56,36,1573,2396,715,1356,786
|
-0.03116783582721283,4.2448520289605876,2.0747334217602056,-0.3173625574811562,1.3945857941684383,-1.2720155125700963,1.007413609708006,2.3536390018116236,0.20678635338280518,0.6830652924493599,0.13990709897991843,0.07215573022457085,1.0643882560099536,0.13990709897991843,-0.24429845596012587,-0.20814992181924744,-0.24429845596012587,-0.13661678053279144,-0.6586680831224061,1.421252266939875,-0.1722571888650981,0.03794435657742731,-1.0614818199989162,-0.3542766862538596,0.10614213666844603,-1.4447588451088091,0.6525998327464225,-1.401215472847145,0.13990709897991843,0.3703398545461924,-0.06607616153332166,-0.24429845596012587,0.20678635338280518,0.7434871462800804,0.003504403042592986,-0.3542766862538596,0.10614213666844603,-0.24429845596012587,-0.3173625574811562,0.003504403042592986,1.120785882156883,0.6525998327464225,-1.0614818199989162,-0.619742816254357,0.6830652924493599,-0.5810666157787491,2.7067183339097847,0.6830652924493599,0.7133603055860006,0.20678635338280518,0.5601572877142909,0.17345405363114286,0.40245027954676366,0.43436739361353727,1.0643882560099536,-0.5044640170129534,0.27281999715468874,-0.3542766862538596,-0.3173625574811562,0.5911482301983078,1.0359739469793032,-1.4447588451088091,-0.20814992181924744,1.0359739469793032,0.7133603055860006,0.6219616032562505,0.40245027954676366,1.204330560625009,0.8032451697533327,2.4438277655987086,3.040853068845477,-0.28070290912863155,-1.532557517479962,0.3380332804355645,-0.13661678053279144,0.27281999715468874
| 2,468
|
Metalloprotease
| 11
| 22
| 2.623195
| 0.008711
|
O75976,O75844,Q9BYT8,Q5JRX3,Q9UIQ6,P42892,Q9NQW7,O43847,P52888,Q9NZ08,P55786
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
359,476,242,145,45,75,313,138,339,152,26
|
1293,138,1886,476,359,906,1014,725,75,339,26,145,1087,851,1046,242,711,534,313,152,45,1956
|
-0.13661678053279144,1.421252266939875,-0.5426401305377743,0.5911482301983078,0.7434871462800804,0.13990709897991843,0.07215573022457085,0.3055276524649288,2.0029346640137495,0.8032451697533327,3.416142107313884,1.421252266939875,0.03794435657742731,0.20678635338280518,0.07215573022457085,1.0359739469793032,0.3380332804355645,0.5289862962916688,0.8623566262060067,1.3945857941684383,2.6420354190598694,-0.5810666157787491
| 2,468
|
metalloprotease
| 11
| 22
| 2.590374
| 0.009587
|
O75844,Q9BYT8,Q8IYS1,Q5JRX3,Q9UIQ6,P42892,O43847,P52888,Q10713,Q9NZ08,P55786
|
Functions
|
Panther Protein class
|
panther_protein_class
|
476,242,274,145,45,75,138,339,408,152,26
|
138,1886,476,1246,1014,725,587,1122,625,75,339,26,408,145,1087,274,1046,242,534,152,45,1956
|
1.421252266939875,-0.5426401305377743,0.5911482301983078,-0.10122447507190645,0.07215573022457085,0.3055276524649288,0.43436739361353727,0.003504403042592986,0.40245027954676366,2.0029346640137495,0.8032451697533327,3.416142107313884,0.6830652924493599,1.421252266939875,0.03794435657742731,0.9498475469241873,0.07215573022457085,1.0359739469793032,0.5289862962916688,1.3945857941684383,2.6420354190598694,-0.5810666157787491
| 2,468
|
Polymicrogyria
| 20
| 63
| 2.566608
| 0.01027
|
Q96EK5,Q05639,Q10713,Q9Y4A5,Q15392,P49591,Q9UN37,Q9NZ01,Q9Y487,Q01105,P38606,Q9BVA1,Q96F86,Q12756,P23786,P37268,P07437,Q08J23,Q6ZXV5,Q8TD16
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
137,149,408,166,40,170,315,331,68,73,199,344,343,341,89,219,216,109,370,127
|
817,948,1363,401,1157,216,1116,1068,1480,2006,1370,89,560,1374,1426,219,199,694,1597,544,1754,170,1485,873,874,2185,564,73,149,109,408,341,1557,1267,880,1505,504,40,1030,1715,1272,1620,370,846,127,853,137,343,2259,530,344,889,2125,1629,331,650,315,1732,1921,68,166,1412,1292
|
0.20678635338280518,0.10614213666844603,-0.1722571888650981,0.6830652924493599,-0.03116783582721283,1.0643882560099536,0.003504403042592986,0.03794435657742731,-0.24429845596012587,-0.6586680831224061,-0.1722571888650981,1.8319466790670544,0.4660939704199051,-0.1722571888650981,-0.20814992181924744,1.0643882560099536,1.120785882156883,0.3380332804355645,-0.3173625574811562,0.49763272112609636,-0.4288655702071363,1.259345097312692,-0.24429845596012587,0.17345405363114286,0.17345405363114286,-0.8974146674576974,0.4660939704199051,2.0269638105009165,1.3945857941684383,1.6302362443481822,0.6830652924493599,0.8032451697533327,-0.28070290912863155,-0.10122447507190645,0.17345405363114286,-0.24429845596012587,0.5601572877142909,2.813054466119539,0.07215573022457085,-0.391444589562264,-0.10122447507190645,-0.3173625574811562,0.7434871462800804,0.20678635338280518,1.474214893902258,0.20678635338280518,1.4477948419810402,0.8032451697533327,-1.0201000011979868,0.5289862962916688,0.8032451697533327,0.17345405363114286,-0.7769319049938614,-0.3173625574811562,0.8328806677236555,0.40245027954676366,0.8623566262060067,-0.391444589562264,-0.5426401305377743,2.1691433864655685,1.3138288708840293,-0.1722571888650981,-0.10122447507190645
| 2,468
|
Negative regulation of cell development
| 7
| 20
| 2.560218
| 0.010461
|
P30536,Q9Y4G8,Q96G23,Q8IXJ6,O43707,P49841,P21359
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,7,241,110,244,337,303
|
244,950,303,64,1311,1752,1425,1217,337,920,1131,598,110,1038,241,576,716,1524,439,7
|
1.007413609708006,0.10614213666844603,0.8623566262060067,2.2620942289667187,-0.13661678053279144,-0.4288655702071363,-0.20814992181924744,-0.06607616153332166,0.8032451697533327,0.13990709897991843,0.003504403042592986,0.43436739361353727,1.6302362443481822,0.07215573022457085,1.0359739469793032,0.4660939704199051,0.3380332804355645,-0.24429845596012587,0.6525998327464225,4.329093172854691
| 2,468
|
Mapk family signaling cascades
| 14
| 80
| 2.534905
| 0.011248
|
Q99436,P49721,P60900,P49720,P28070,Q9Y4G8,P30153,O15020,Q13618,O00231,P20618,P30154,P28074,O60725
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
96,65,125,255,38,7,140,231,211,264,117,269,60,63
|
264,1056,1293,1686,947,231,541,63,1471,2155,2367,904,1478,1210,1120,117,303,1071,1167,1212,1213,1540,1250,870,38,543,60,588,1373,140,269,1214,2308,2250,1847,659,797,1651,1019,1074,255,65,799,1317,964,125,2293,1263,1759,1320,1175,1078,802,2185,1081,1265,1977,1603,1440,840,211,666,667,1179,1713,479,633,804,809,1095,96,1097,781,1833,1288,677,1234,2346,1637,7
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.10614213666844603,1.0359739469793032,0.49763272112609636,2.3080391779465006,-0.24429845596012587,-0.8570082192801957,-1.401215472847145,0.13990709897991843,-0.24429845596012587,-0.06607616153332166,0.003504403042592986,1.5527533004356622,0.8623566262060067,0.03794435657742731,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,-0.10122447507190645,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,0.43436739361353727,-0.1722571888650981,1.421252266939875,0.9498475469241873,-0.06607616153332166,-1.187079359251964,-1.0201000011979868,-0.5044640170129534,0.3703398545461924,0.23990727005026555,-0.3542766862538596,0.07215573022457085,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,-0.13661678053279144,0.10614213666844603,1.474214893902258,-1.144972064254425,-0.10122447507190645,-0.4288655702071363,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,0.23990727005026555,-0.8974146674576974,0.03794435657742731,-0.10122447507190645,-0.619742816254357,-0.3173625574811562,-0.20814992181924744,0.20678635338280518,1.0926583185496224,0.3703398545461924,0.3703398545461924,-0.03116783582721283,-0.391444589562264,0.5911482301983078,0.40245027954676366,0.23990727005026555,0.23990727005026555,0.03794435657742731,1.757119144304389,0.03794435657742731,0.27281999715468874,-0.4665389394864189,-0.10122447507190645,0.3703398545461924,-0.06607616153332166,-1.2720155125700963,-0.3173625574811562,4.329093172854691
| 2,468
|
Metalloexopeptidase activity
| 7
| 17
| 2.514079
| 0.011934
|
O75844,Q9UIQ6,Q9NQW7,P50579,O75976,P55786,Q9NZ08
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
476,45,313,50,359,26,152
|
476,359,1246,906,1014,1122,660,50,26,1087,852,1948,711,534,313,152,45
|
0.5911482301983078,0.7434871462800804,-0.10122447507190645,0.13990709897991843,0.07215573022457085,0.003504403042592986,0.3703398545461924,2.5547286368600663,3.416142107313884,0.03794435657742731,0.20678635338280518,-0.5810666157787491,0.3380332804355645,0.5289862962916688,0.8623566262060067,1.3945857941684383,2.6420354190598694
| 2,468
|
Zinc ion binding
| 26
| 108
| 2.460433
| 0.013877
|
Q5JPH6,Q9Y3Z3,Q03164,Q5JRX3,P00813,Q9Y4X5,Q9NZ08,P55786,P19474,Q15437,Q8N4Q0,Q8NB78,Q9UIQ6,Q8N8N7,Q15436,P34896,Q9NUD5,P34949,P42892,Q9NWV4,P29372,Q14527,Q9H9B1,Q8IXJ6,Q07864,O75976
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
259,394,133,145,18,289,152,26,29,159,32,293,45,52,55,61,194,67,75,347,208,212,378,110,118,359
|
1735,754,1884,517,490,359,1690,1580,721,1419,493,1780,18,759,950,558,1367,1160,906,907,725,1304,29,522,1016,1017,763,1697,208,1894,61,560,67,660,75,765,627,1969,832,1546,1653,1126,1318,26,918,133,1382,1223,118,1385,1324,1176,212,1389,1503,1136,1390,1811,55,159,1812,1941,1394,259,145,1615,2116,1717,702,2166,1276,434,1277,110,32,52,293,465,2028,850,1912,603,1947,2274,1627,1343,1948,931,1048,711,378,2395,1880,194,347,152,392,1053,536,1999,45,2196,2303,862,394,1956,289,1001
|
-0.4288655702071363,0.27281999715468874,-0.5426401305377743,0.5289862962916688,0.5601572877142909,0.7434871462800804,-0.391444589562264,-0.3173625574811562,0.3055276524649288,-0.20814992181924744,0.5601572877142909,-0.4665389394864189,3.8253149596469553,0.27281999715468874,0.10614213666844603,0.4660939704199051,-0.1722571888650981,-0.03116783582721283,0.13990709897991843,0.13990709897991843,0.3055276524649288,-0.13661678053279144,3.338926259238387,0.5289862962916688,0.07215573022457085,0.07215573022457085,0.27281999715468874,-0.391444589562264,1.0926583185496224,-0.5426401305377743,2.3536390018116236,0.4660939704199051,2.1691433864655685,0.3703398545461924,2.0029346640137495,0.27281999715468874,0.40245027954676366,-0.619742816254357,0.20678635338280518,-0.28070290912863155,-0.3542766862538596,0.003504403042592986,-0.13661678053279144,3.416142107313884,0.13990709897991843,1.4477948419810402,-0.1722571888650981,-0.06607616153332166,1.5527533004356622,-0.1722571888650981,-0.13661678053279144,-0.03116783582721283,1.0926583185496224,-0.1722571888650981,-0.24429845596012587,0.003504403042592986,-0.1722571888650981,-0.4665389394864189,2.4438277655987086,1.3408755334440563,-0.4665389394864189,-0.5810666157787491,-0.1722571888650981,0.9787054273330804,1.421252266939875,-0.3173625574811562,-0.7769319049938614,-0.391444589562264,0.3380332804355645,-0.8570082192801957,-0.10122447507190645,0.6525998327464225,-0.10122447507190645,1.6302362443481822,3.101586092860153,2.488428526046467,0.8916750939887781,0.6219616032562505,-0.6586680831224061,0.20678635338280518,-0.5426401305377743,0.43436739361353727,-0.5810666157787491,-1.0614818199989162,-0.3173625574811562,-0.13661678053279144,-0.5810666157787491,0.13990709897991843,0.07215573022457085,0.3380332804355645,0.7434871462800804,-1.532557517479962,-0.5044640170129534,1.1487726610909024,0.8032451697533327,1.3945857941684383,0.7133603055860006,0.07215573022457085,0.5289862962916688,-0.619742816254357,2.6420354190598694,-0.8974146674576974,-1.144972064254425,0.20678635338280518,0.7133603055860006,-0.5810666157787491,0.9208380784964595,0.10614213666844603
| 2,468
|
Class i mhc mediated antigen processing presentation
| 32
| 94
| 2.450872
| 0.014251
|
P60900,P49720,O94874,O00231,Q9NZ08,Q9H1A4,P55786,Q9UJX4,P19474,Q13867,P49427,Q92990,Q15386,A0AVT1,P28070,P28072,Q9UIQ6,Q15436,P68036,P28074,P49721,Q9C0C9,Q13618,P52888,Q9Y4B6,Q99436,P09429,Q15008,Q9UJX3,P20618,O95376,O94979
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,255,518,264,152,157,26,556,29,282,405,437,549,37,38,543,45,55,427,60,65,469,211,339,229,96,217,479,512,117,493,491
|
37,1774,264,1056,1293,1686,541,2102,2155,518,491,493,584,217,761,1210,29,117,1306,1167,1212,1213,1540,1697,1790,870,38,543,60,1590,1792,1018,2250,1651,1074,405,255,65,2378,799,339,1126,964,26,1900,2018,125,1932,1600,1656,1263,2141,1320,1175,1078,919,427,2413,2228,1603,1761,840,1560,1808,211,282,1610,1713,479,843,2022,549,55,566,2116,1276,884,1721,437,706,641,96,1097,469,157,152,45,676,512,556,677,1463,1234,229
|
2.9589633825131183,-0.4665389394864189,0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.7769319049938614,-0.8570082192801957,0.5289862962916688,0.5601572877142909,0.5601572877142909,0.43436739361353727,1.0643882560099536,0.27281999715468874,-0.06607616153332166,3.338926259238387,1.5527533004356622,-0.13661678053279144,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,-0.391444589562264,-0.4665389394864189,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-0.3173625574811562,-0.4665389394864189,0.07215573022457085,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.6830652924493599,0.9787054273330804,2.2620942289667187,-1.4447588451088091,0.23990727005026555,0.8032451697533327,0.003504403042592986,0.10614213666844603,3.416142107313884,-0.5426401305377743,-0.6586680831224061,1.474214893902258,-0.5810666157787491,-0.3173625574811562,-0.3542766862538596,-0.10122447507190645,-0.8168470964124629,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,0.13990709897991843,0.6525998327464225,-1.7109882266710317,-0.9789611482255609,-0.3173625574811562,-0.4288655702071363,0.20678635338280518,-0.28070290912863155,-0.4665389394864189,1.0926583185496224,0.9208380784964595,-0.3173625574811562,-0.391444589562264,0.5911482301983078,0.20678635338280518,-0.6586680831224061,0.49763272112609636,2.4438277655987086,0.4660939704199051,-0.7769319049938614,-0.10122447507190645,0.17345405363114286,-0.391444589562264,0.6525998327464225,0.3380332804355645,0.40245027954676366,1.757119144304389,0.03794435657742731,0.6219616032562505,1.3677940244677216,1.3945857941684383,2.6420354190598694,0.3703398545461924,0.5601572877142909,0.49763272112609636,0.3703398545461924,-0.20814992181924744,-0.06607616153332166,1.0643882560099536
| 2,468
|
Negative regulation of nervous system development
| 7
| 15
| 2.437722
| 0.01478
|
P30536,Q9UPY3,Q9Y4G8,Q96G23,Q8IXJ6,Q9NQC3,P21359
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,439,7,241,110,576,303
|
950,303,64,1311,1752,1425,920,1131,598,110,1038,241,576,439,7
|
0.10614213666844603,0.8623566262060067,2.2620942289667187,-0.13661678053279144,-0.4288655702071363,-0.20814992181924744,0.13990709897991843,0.003504403042592986,0.43436739361353727,1.6302362443481822,0.07215573022457085,1.0359739469793032,0.4660939704199051,0.6525998327464225,4.329093172854691
| 2,468
|
Mitotic spindle
| 12
| 19
| 2.418677
| 0.015577
|
Q00610,Q9Y6A5,P07437,P68371,Q13885,Q9NWV4,Q9BVA1,Q14203,Q8WWK9,P52732,P04350,Q9NR09
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
564,300,216,201,384,347,344,503,570,426,402,93
|
402,1115,216,1749,426,201,564,1493,384,503,1137,1338,570,644,344,93,347,2001,300
|
0.6830652924493599,0.003504403042592986,1.0643882560099536,-0.4288655702071363,0.6525998327464225,1.120785882156883,0.4660939704199051,-0.24429845596012587,0.7133603055860006,0.5601572877142909,0.003504403042592986,-0.13661678053279144,0.4660939704199051,0.40245027954676366,0.8032451697533327,1.8071100900408057,0.8032451697533327,-0.619742816254357,0.8916750939887781
| 2,468
|
Limb joint contracture
| 23
| 73
| 2.410029
| 0.015951
|
P40763,Q96AY3,Q8IWS0,O00469,P46109,Q15392,Q9Y3E5,P63241,P06753,P35637,P27635,Q5JTV8,O60231,P42892,Q86XL3,P23786,P37268,O75844,Q7LGA3,Q08J23,Q15042,Q99567,Q8TD16
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
141,286,285,400,280,40,443,171,420,423,58,460,445,75,83,89,219,476,237,109,504,510,127
|
400,817,948,445,820,2202,2154,476,1206,420,1067,623,792,1587,1249,542,1306,89,58,588,1123,2075,423,219,141,1073,75,280,662,1485,697,801,171,1936,698,970,109,1267,1084,1027,1179,1502,1505,504,1980,40,460,1619,2118,237,83,285,1037,2121,127,671,1987,2374,1723,286,572,510,1344,2284,1190,1951,2037,443,1291,1412,1292,515,1001
|
0.6830652924493599,0.20678635338280518,0.10614213666844603,0.6219616032562505,0.20678635338280518,-0.9380658414393885,-0.8570082192801957,0.5911482301983078,-0.06607616153332166,0.6525998327464225,0.03794435657742731,0.40245027954676366,0.23990727005026555,-0.3173625574811562,-0.10122447507190645,0.49763272112609636,-0.13661678053279144,1.8319466790670544,2.376311425532409,0.43436739361353727,0.003504403042592986,-0.7372632579290869,0.6525998327464225,1.0643882560099536,1.421252266939875,0.03794435657742731,2.0029346640137495,0.9208380784964595,0.3703398545461924,-0.24429845596012587,0.3380332804355645,0.23990727005026555,1.259345097312692,-0.5810666157787491,0.3380332804355645,0.10614213666844603,1.6302362443481822,-0.10122447507190645,0.03794435657742731,0.07215573022457085,-0.03116783582721283,-0.24429845596012587,-0.24429845596012587,0.5601572877142909,-0.619742816254357,2.813054466119539,0.6219616032562505,-0.3173625574811562,-0.7769319049938614,1.0359739469793032,1.9302585215562786,0.9208380784964595,0.07215573022457085,-0.7769319049938614,1.474214893902258,0.3703398545461924,-0.619742816254357,-1.401215472847145,-0.391444589562264,0.9208380784964595,0.4660939704199051,0.5601572877142909,-0.13661678053279144,-1.103106030413342,-0.03116783582721283,-0.5810666157787491,-0.6586680831224061,0.6525998327464225,-0.10122447507190645,-0.1722571888650981,-0.10122447507190645,0.5601572877142909,0.10614213666844603
| 2,468
|
Regulation of autophagy
| 19
| 76
| 2.40587
| 0.016134
|
Q93050,P40763,Q05639,P19474,O15269,O00429,Q96EB6,P30536,Q9Y487,P07602,P38606,P21796,Q08379,P49841,P09429,Q9NZ45,Q8IYI6,Q8IXJ6,P54646
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
13,141,149,29,278,161,172,64,68,72,199,317,340,337,217,102,239,110,363
|
655,161,1924,278,1957,2102,1203,476,518,686,1473,950,2367,2204,2205,72,955,1840,217,2106,2043,1474,2292,1478,29,691,1370,1371,317,1250,64,199,141,1597,626,1217,337,363,1655,967,1079,1264,920,595,149,340,1135,700,1269,504,1274,1445,110,239,2298,1143,13,172,603,886,2193,810,889,1191,1287,414,1833,102,939,1731,1575,679,1356,537,2220,68
|
0.3703398545461924,1.3138288708840293,-0.5810666157787491,0.9208380784964595,-0.619742816254357,-0.7769319049938614,-0.06607616153332166,0.5911482301983078,0.5289862962916688,0.3380332804355645,-0.24429845596012587,0.10614213666844603,-1.401215472847145,-0.9380658414393885,-0.9380658414393885,2.0269638105009165,0.10614213666844603,-0.5044640170129534,1.0643882560099536,-0.7769319049938614,-0.6978417750235022,-0.24429845596012587,-1.144972064254425,-0.24429845596012587,3.338926259238387,0.3380332804355645,-0.1722571888650981,-0.1722571888650981,0.8328806677236555,-0.10122447507190645,2.2620942289667187,1.120785882156883,1.421252266939875,-0.3173625574811562,0.40245027954676366,-0.06607616153332166,0.8032451697533327,0.7434871462800804,-0.3542766862538596,0.10614213666844603,0.03794435657742731,-0.10122447507190645,0.13990709897991843,0.43436739361353727,1.3945857941684383,0.8032451697533327,0.003504403042592986,0.3380332804355645,-0.10122447507190645,0.5601572877142909,-0.10122447507190645,-0.20814992181924744,1.6302362443481822,1.0359739469793032,-1.144972064254425,0.003504403042592986,4.05578531684179,1.259345097312692,0.43436739361353727,0.17345405363114286,-0.8974146674576974,0.23990727005026555,0.17345405363114286,-0.03116783582721283,-0.10122447507190645,0.6830652924493599,-0.4665389394864189,1.706697187026586,0.13990709897991843,-0.391444589562264,-0.28070290912863155,0.3703398545461924,-0.13661678053279144,0.5289862962916688,-0.9380658414393885,2.1691433864655685
| 2,468
|
Sealing of the nuclear envelope ne by escrt iii
| 6
| 10
| 2.353701
| 0.018588
|
P68371,Q8NC56,Q13885,Q9UN37,Q9BVA1,O43633
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
201,373,384,315,344,357
|
357,402,1259,201,384,373,644,344,315,1054
|
0.7434871462800804,0.6830652924493599,-0.10122447507190645,1.120785882156883,0.7133603055860006,0.7434871462800804,0.40245027954676366,0.8032451697533327,0.8623566262060067,0.07215573022457085
| 2,468
|
Knee flexion contracture
| 9
| 20
| 2.349538
| 0.018797
|
P27635,Q7LGA3,Q86XL3,P06753,Q8TD16,Q96AY3,P23786,O00469,P37268
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
58,237,83,420,127,286,89,400,219
|
400,445,2202,2154,420,1249,542,1306,89,58,1123,219,970,237,83,127,286,1291,1412,1292
|
0.6830652924493599,0.6219616032562505,-0.9380658414393885,-0.8570082192801957,0.6525998327464225,-0.10122447507190645,0.49763272112609636,-0.13661678053279144,1.8319466790670544,2.376311425532409,0.003504403042592986,1.0643882560099536,0.10614213666844603,1.0359739469793032,1.9302585215562786,1.474214893902258,0.9208380784964595,-0.10122447507190645,-0.1722571888650981,-0.10122447507190645
| 2,468
|
Metallopeptidase activity
| 14
| 35
| 2.34886
| 0.018831
|
O75976,O75844,Q9BYT8,Q5JRX3,Q9UIQ6,P42892,Q9NQW7,O43847,P50579,P52888,Q10713,Q9NZ08,P55786,O15372
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
359,476,242,145,45,75,313,138,50,339,408,152,26,489
|
897,1293,489,138,1886,476,359,1246,906,1014,725,587,1122,660,75,50,799,339,26,408,145,1332,1140,1087,851,852,1046,1948,242,711,534,313,152,45,1956
|
0.13990709897991843,-0.13661678053279144,0.5601572877142909,1.421252266939875,-0.5426401305377743,0.5911482301983078,0.7434871462800804,-0.10122447507190645,0.13990709897991843,0.07215573022457085,0.3055276524649288,0.43436739361353727,0.003504403042592986,0.3703398545461924,2.0029346640137495,2.5547286368600663,0.23990727005026555,0.8032451697533327,3.416142107313884,0.6830652924493599,1.421252266939875,-0.13661678053279144,0.003504403042592986,0.03794435657742731,0.20678635338280518,0.20678635338280518,0.07215573022457085,-0.5810666157787491,1.0359739469793032,0.3380332804355645,0.5289862962916688,0.8623566262060067,1.3945857941684383,2.6420354190598694,-0.5810666157787491
| 2,468
|
Phospholipid binding
| 22
| 67
| 2.345406
| 0.019006
|
P35080,Q9Y4G8,Q13045,P45880,Q14108,O15294,Q8WTV0,Q86YQ8,Q8N668,O60749,P21359,Q8NCC3,Q9BZF1,P07602,P21796,P09429,Q8IYI6,Q7Z3T8,O15020,Q92538,O43633,Q9H6U6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
253,7,150,404,30,279,35,435,308,417,303,465,204,72,317,217,239,238,231,240,357,250
|
898,444,231,279,357,582,820,1415,417,949,1694,1891,72,687,1366,217,760,1301,1749,1368,303,317,1789,1373,253,590,404,544,1019,1125,914,1174,1799,2159,1081,150,1903,30,1026,1612,1390,2115,238,435,239,308,465,35,240,2417,1094,1948,930,1345,204,2342,2394,250,939,1197,893,578,514,679,1637,7,654
|
0.13990709897991843,0.6219616032562505,1.0359739469793032,0.9208380784964595,0.7434871462800804,0.43436739361353727,0.20678635338280518,-0.20814992181924744,0.6525998327464225,0.10614213666844603,-0.391444589562264,-0.5426401305377743,2.0269638105009165,0.3380332804355645,-0.1722571888650981,1.0643882560099536,0.27281999715468874,-0.13661678053279144,-0.4288655702071363,-0.1722571888650981,0.8623566262060067,0.8328806677236555,-0.4665389394864189,-0.1722571888650981,0.9787054273330804,0.43436739361353727,0.6830652924493599,0.49763272112609636,0.07215573022457085,0.003504403042592986,0.13990709897991843,-0.03116783582721283,-0.4665389394864189,-0.8570082192801957,0.03794435657742731,1.3945857941684383,-0.5426401305377743,3.181676304646078,0.07215573022457085,-0.3173625574811562,-0.1722571888650981,-0.7769319049938614,1.0359739469793032,0.6525998327464225,1.0359739469793032,0.8623566262060067,0.6219616032562505,3.0611617440095436,1.0359739469793032,-1.7109882266710317,0.03794435657742731,-0.5810666157787491,0.13990709897991843,-0.13661678053279144,1.120785882156883,-1.2720155125700963,-1.532557517479962,1.007413609708006,0.13990709897991843,-0.03116783582721283,0.17345405363114286,0.4660939704199051,0.5601572877142909,0.3703398545461924,-0.3173625574811562,4.329093172854691,0.40245027954676366
| 2,468
|
Regulation of cell development
| 14
| 68
| 2.321626
| 0.020253
|
P30536,Q9UQB8,Q9UL25,P55209,Q9Y4G8,P21359,Q96G23,Q8IXJ6,O43707,P26583,Q14185,Q9BXP5,Q7L576,P46109
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,2,299,323,7,303,241,110,244,246,88,287,124,280
|
475,753,244,1531,2003,518,950,867,724,1120,1249,303,246,1696,1697,64,1311,1752,1425,589,2045,1597,962,280,544,1217,337,913,1259,323,2293,1221,2185,1264,664,920,1265,1131,1383,1135,1177,1441,1268,88,1025,598,979,124,110,1038,2085,1094,241,1992,572,287,2285,1284,576,716,2237,299,1524,1634,861,439,2,7
|
0.5911482301983078,0.27281999715468874,1.007413609708006,-0.28070290912863155,-0.6586680831224061,0.5289862962916688,0.10614213666844603,0.17345405363114286,0.3055276524649288,0.003504403042592986,-0.10122447507190645,0.8623566262060067,1.007413609708006,-0.391444589562264,-0.391444589562264,2.2620942289667187,-0.13661678053279144,-0.4288655702071363,-0.20814992181924744,0.43436739361353727,-0.6978417750235022,-0.3173625574811562,0.10614213666844603,0.9208380784964595,0.49763272112609636,-0.06607616153332166,0.8032451697533327,0.13990709897991843,-0.10122447507190645,0.8328806677236555,-1.144972064254425,-0.06607616153332166,-0.8974146674576974,-0.10122447507190645,0.3703398545461924,0.13990709897991843,-0.10122447507190645,0.003504403042592986,-0.1722571888650981,0.003504403042592986,-0.03116783582721283,-0.20814992181924744,-0.10122447507190645,1.8813074269920262,0.07215573022457085,0.43436739361353727,0.10614213666844603,1.5005137733127836,1.6302362443481822,0.07215573022457085,-0.7372632579290869,0.03794435657742731,1.0359739469793032,-0.619742816254357,0.4660939704199051,0.9208380784964595,-1.103106030413342,-0.10122447507190645,0.4660939704199051,0.3380332804355645,-0.9789611482255609,0.8916750939887781,-0.24429845596012587,-0.3173625574811562,0.20678635338280518,0.6525998327464225,4.640166608697676,4.329093172854691
| 2,468
|
protease
| 11
| 39
| 2.318389
| 0.020428
|
P60900,P49721,Q99436,P49720,P28070,P42575,Q9BT78,Q9NQW7,P50579,P20618,P28074
|
Functions
|
Panther Protein class
|
panther_protein_class
|
125,65,96,255,38,70,375,313,50,117,60
|
1056,1686,541,359,1690,1210,117,1167,1212,1213,1540,870,38,543,60,2250,626,70,1651,1074,255,65,50,964,125,1320,1175,1078,840,1562,96,1097,375,1771,607,313,1234,652,612
|
0.03794435657742731,-0.391444589562264,0.49763272112609636,0.7434871462800804,-0.391444589562264,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,0.40245027954676366,2.0747334217602056,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,2.5547286368600663,0.10614213666844603,1.474214893902258,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,0.20678635338280518,-0.28070290912863155,1.757119144304389,0.03794435657742731,0.7434871462800804,-0.4288655702071363,0.43436739361353727,0.8623566262060067,-0.06607616153332166,0.40245027954676366,0.43436739361353727
| 2,468
|
Dna replication
| 14
| 75
| 2.314705
| 0.020629
|
P60900,Q8N257,P49721,P49720,Q99436,P28070,P40938,P33991,Q14566,P24941,P20618,Q07864,Q9H1A4,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,164,65,255,96,38,220,271,272,207,117,118,157,60
|
264,1056,1293,1686,541,2264,1243,2155,1160,1475,1210,117,207,1165,1167,1212,1213,1540,762,870,38,543,60,2073,1018,271,910,1592,1966,829,1593,2250,1428,1314,220,1651,1074,1433,255,65,696,799,1316,964,125,1263,1320,1175,1078,2379,919,1603,118,840,1559,1560,272,1136,1713,479,566,567,164,96,1097,1146,157,2450,676,512,556,677,1234,537,515
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-1.0614818199989162,-0.10122447507190645,-0.8570082192801957,-0.03116783582721283,-0.24429845596012587,-0.06607616153332166,1.5527533004356622,1.0926583185496224,-0.03116783582721283,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.27281999715468874,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-0.7372632579290869,0.07215573022457085,0.9498475469241873,0.13990709897991843,-0.3173625574811562,-0.619742816254357,0.20678635338280518,-0.3173625574811562,-1.0201000011979868,-0.20814992181924744,-0.13661678053279144,1.0643882560099536,-0.3542766862538596,0.03794435657742731,-0.20814992181924744,0.9787054273330804,2.2620942289667187,0.3380332804355645,0.23990727005026555,-0.13661678053279144,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-1.4447588451088091,0.13990709897991843,-0.3173625574811562,1.5527533004356622,0.20678635338280518,-0.28070290912863155,-0.28070290912863155,0.9498475469241873,0.003504403042592986,-0.391444589562264,0.5911482301983078,0.4660939704199051,0.4660939704199051,1.3138288708840293,1.757119144304389,0.03794435657742731,0.003504403042592986,1.3677940244677216,-2.510801887820688,0.3703398545461924,0.5601572877142909,0.49763272112609636,0.3703398545461924,-0.06607616153332166,0.5289862962916688,0.5601572877142909
| 2,468
|
Muscle stiffness
| 8
| 16
| 2.306925
| 0.021059
|
Q8NBU5,Q9Y3Z3,Q15392,P07602,P11166,Q12756,P06753,P23786
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
100,394,40,72,174,341,420,89
|
1889,420,72,174,89,1970,426,546,1077,341,40,1333,100,939,394,2099
|
-0.5426401305377743,0.6525998327464225,2.0269638105009165,1.2319049508681916,1.8319466790670544,-0.619742816254357,0.6525998327464225,0.49763272112609636,0.03794435657742731,0.8032451697533327,2.813054466119539,-0.13661678053279144,1.7319626002078956,0.13990709897991843,0.7133603055860006,-0.7372632579290869
| 2,468
|
Wormian bones
| 9
| 16
| 2.295489
| 0.021705
|
Q68CP9,Q9Y487,Q32P28,Q8NC56,O95831,Q12756,O75718,Q96AY3,O00469
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
351,68,385,373,290,341,418,286,400
|
400,418,476,290,1206,867,1249,2179,697,341,1389,385,351,373,286,68
|
0.6830652924493599,0.6525998327464225,0.5911482301983078,0.8916750939887781,-0.06607616153332166,0.17345405363114286,-0.10122447507190645,-0.8974146674576974,0.3380332804355645,0.8032451697533327,-0.1722571888650981,0.7133603055860006,0.7734480409672624,0.7434871462800804,0.9208380784964595,2.1691433864655685
| 2,468
|
Lipid localization
| 13
| 57
| 2.295431
| 0.021708
|
P30536,Q8WTV0,P35790,Q9BZF1,P07602,P08183,Q96EB6,Q9BQE5,O43772,P11166,Q9H6V9,P23786,Q14108
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,35,39,204,72,103,172,14,16,174,20,89,30
|
1240,1924,16,1736,1006,864,1158,2176,686,1694,1891,72,2464,558,103,174,198,2107,1789,2108,89,1698,1894,64,764,1169,796,39,1125,1022,1977,30,2312,599,844,2297,2024,464,2256,35,172,1449,2192,1344,14,1345,1346,204,533,20,939,1998,288,996,893,315,1638
|
-0.10122447507190645,-0.5810666157787491,3.8792061948428853,-0.4288655702071363,0.07215573022457085,0.17345405363114286,-0.03116783582721283,-0.8974146674576974,0.3380332804355645,-0.391444589562264,-0.5426401305377743,2.0269638105009165,-3.8054916366383664,0.4660939704199051,1.6813217654422683,1.2319049508681916,1.120785882156883,-0.7769319049938614,-0.4665389394864189,-0.7769319049938614,1.8319466790670544,-0.391444589562264,-0.5426401305377743,2.2620942289667187,0.27281999715468874,-0.03116783582721283,0.23990727005026555,2.813054466119539,0.003504403042592986,0.07215573022457085,-0.619742816254357,3.181676304646078,-1.187079359251964,0.43436739361353727,0.20678635338280518,-1.144972064254425,-0.6586680831224061,0.6219616032562505,-1.0201000011979868,3.0611617440095436,1.259345097312692,-0.20814992181924744,-0.8974146674576974,-0.13661678053279144,4.038333838427878,-0.13661678053279144,-0.13661678053279144,1.120785882156883,0.5289862962916688,3.7345183456643567,0.13990709897991843,-0.619742816254357,0.9208380784964595,0.10614213666844603,0.17345405363114286,0.8623566262060067,-0.3173625574811562
| 2,468
|
Endopeptidase activity
| 19
| 50
| 2.258949
| 0.023887
|
P60900,P49720,Q5JRX3,O43847,Q4J6C6,Q9NZ08,Q13867,P28070,Q93009,P28074,Q9UPU5,P49721,P42575,P42892,P52888,Q99436,Q9BYT8,Q86UV5,P20618
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
125,255,145,138,151,152,282,38,178,60,195,65,70,75,339,96,242,371,117
|
898,138,1886,476,2205,1065,1247,725,117,587,1540,38,543,60,1590,1792,1426,626,70,75,627,831,255,65,339,1704,125,2372,408,282,1269,732,151,145,1668,371,1512,849,2417,851,1280,178,1046,96,1948,242,1191,152,195,1956
|
0.13990709897991843,1.421252266939875,-0.5426401305377743,0.5911482301983078,-0.9380658414393885,0.03794435657742731,-0.10122447507190645,0.3055276524649288,1.5527533004356622,0.43436739361353727,-0.28070290912863155,2.8550887102218057,0.49763272112609636,2.3536390018116236,-0.3173625574811562,-0.4665389394864189,-0.20814992181924744,0.40245027954676366,2.0747334217602056,2.0029346640137495,0.40245027954676366,0.20678635338280518,0.9787054273330804,2.2620942289667187,0.8032451697533327,-0.391444589562264,1.474214893902258,-1.401215472847145,0.6830652924493599,0.9208380784964595,-0.10122447507190645,0.3055276524649288,1.3945857941684383,1.421252266939875,-0.3542766862538596,0.7434871462800804,-0.24429845596012587,0.20678635338280518,-1.7109882266710317,0.20678635338280518,-0.10122447507190645,1.2319049508681916,0.07215573022457085,1.757119144304389,-0.5810666157787491,1.0359739469793032,-0.03116783582721283,1.3945857941684383,1.1487726610909024,-0.5810666157787491
| 2,468
|
Acute viral myocarditis
| 8
| 13
| 2.255954
| 0.024074
|
P42575,P42574,P40763,Q04637,P49841,P78310,P42224,P28482
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
70,626,141,595,337,87,561,588
|
682,1367,1118,1250,588,141,561,626,70,337,87,1264,595
|
0.3380332804355645,-0.1722571888650981,0.003504403042592986,-0.10122447507190645,0.43436739361353727,1.421252266939875,0.4660939704199051,0.40245027954676366,2.0747334217602056,0.8032451697533327,1.8813074269920262,-0.10122447507190645,0.43436739361353727
| 2,468
|
Exopeptidase activity
| 10
| 27
| 2.235139
| 0.025408
|
Q9HB40,Q8IYS1,Q9UIQ6,Q9NQW7,P42785,P50579,Q9H3G5,Q9NZ08,P55786,Q13867
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
298,274,45,313,209,50,377,152,26,282
|
898,476,359,1246,906,2043,1014,1122,1590,660,209,50,26,972,282,1087,274,2271,852,1948,377,711,298,534,313,152,45
|
0.13990709897991843,0.5911482301983078,0.7434871462800804,-0.10122447507190645,0.13990709897991843,-0.6978417750235022,0.07215573022457085,0.003504403042592986,-0.3173625574811562,0.3703398545461924,1.0926583185496224,2.5547286368600663,3.416142107313884,0.10614213666844603,0.9208380784964595,0.03794435657742731,0.9498475469241873,-1.0614818199989162,0.20678635338280518,-0.5810666157787491,0.7434871462800804,0.3380332804355645,0.8916750939887781,0.5289862962916688,0.8623566262060067,1.3945857941684383,2.6420354190598694
| 2,468
|
Cilium assembly
| 19
| 48
| 2.222601
| 0.026243
|
Q92973,A6NIH7,Q13885,P30153,O75935,Q13561,Q10713,P04350,Q9H6D7,P78371,Q9BV73,P48643,O95684,P68371,Q9BVA1,Q15691,P07437,Q8IYI6,Q92538
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
388,11,384,140,148,409,408,402,36,428,184,425,59,201,344,222,216,239,240
|
1154,11,148,59,402,904,216,905,1478,1422,1479,140,1374,1650,962,425,912,663,1218,1655,966,1489,1601,1129,201,428,408,1939,409,384,842,503,880,631,598,222,239,2383,1448,240,388,466,644,184,344,36,2396,1356
|
-0.03116783582721283,4.2448520289605876,1.3945857941684383,2.3536390018116236,0.6830652924493599,0.13990709897991843,1.0643882560099536,0.13990709897991843,-0.24429845596012587,-0.20814992181924744,-0.24429845596012587,1.421252266939875,-0.1722571888650981,-0.3542766862538596,0.10614213666844603,0.6525998327464225,0.13990709897991843,0.3703398545461924,-0.06607616153332166,-0.3542766862538596,0.10614213666844603,-0.24429845596012587,-0.3173625574811562,0.003504403042592986,1.120785882156883,0.6525998327464225,0.6830652924493599,-0.5810666157787491,0.6830652924493599,0.7133603055860006,0.20678635338280518,0.5601572877142909,0.17345405363114286,0.40245027954676366,0.43436739361353727,1.0643882560099536,1.0359739469793032,-1.4447588451088091,-0.20814992181924744,1.0359739469793032,0.7133603055860006,0.6219616032562505,0.40245027954676366,1.204330560625009,0.8032451697533327,3.040853068845477,-1.532557517479962,-0.13661678053279144
| 2,468
|
Enzyme activator activity
| 18
| 84
| 2.212092
| 0.02696
|
O00429,Q9Y4G8,P07602,O43169,Q5JRX3,Q15257,Q14C86,O14737,Q4KMP7,P14635,Q69YN2,Q8TC07,Q15436,Q14185,Q9H6U6,Q9Y263,Q7KZI7,Q15437
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
161,7,72,74,145,144,47,173,247,175,115,311,55,88,250,228,120,159
|
161,1293,1199,173,74,616,865,1690,1890,72,791,2043,1475,724,175,2107,303,1311,1593,659,1794,1649,626,1544,1429,1019,628,1380,2110,1598,1801,1263,2161,1129,1760,427,1936,1265,1603,1761,1440,88,1179,1713,47,1505,504,144,633,55,159,247,145,1618,115,120,2439,1090,311,2193,1873,606,2260,2342,889,1192,250,994,390,575,1403,939,940,535,675,2237,393,677,2001,228,1357,1238,7,1638
|
1.3138288708840293,-0.13661678053279144,-0.06607616153332166,1.2319049508681916,2.0029346640137495,0.40245027954676366,0.17345405363114286,-0.391444589562264,-0.5426401305377743,2.0269638105009165,0.23990727005026555,-0.6978417750235022,-0.24429845596012587,0.3055276524649288,1.2319049508681916,-0.7769319049938614,0.8623566262060067,-0.13661678053279144,-0.3173625574811562,0.3703398545461924,-0.4665389394864189,-0.3542766862538596,0.40245027954676366,-0.28070290912863155,-0.20814992181924744,0.07215573022457085,0.40245027954676366,-0.1722571888650981,-0.7769319049938614,-0.3173625574811562,-0.4665389394864189,-0.10122447507190645,-0.8570082192801957,0.003504403042592986,-0.4288655702071363,0.6525998327464225,-0.5810666157787491,-0.10122447507190645,-0.3173625574811562,-0.4288655702071363,-0.20814992181924744,1.8813074269920262,-0.03116783582721283,-0.391444589562264,2.5985360100891364,-0.24429845596012587,0.5601572877142909,1.421252266939875,0.40245027954676366,2.4438277655987086,1.3408755334440563,1.007413609708006,1.421252266939875,-0.3173625574811562,1.5786965344054507,1.5266928073906822,-2.1734091859789286,0.03794435657742731,0.8623566262060067,-0.8974146674576974,-0.5044640170129534,0.43436739361353727,-1.0201000011979868,-1.2720155125700963,0.17345405363114286,-0.03116783582721283,1.007413609708006,0.10614213666844603,0.7133603055860006,0.4660939704199051,-0.1722571888650981,0.13990709897991843,0.13990709897991843,0.5289862962916688,0.3703398545461924,-0.9789611482255609,0.7133603055860006,0.3703398545461924,-0.619742816254357,1.0643882560099536,-0.13661678053279144,-0.06607616153332166,4.329093172854691,-0.3173625574811562
| 2,468
|
Signaling by the b cell receptor bcr
| 9
| 41
| 2.184281
| 0.028942
|
P60900,P49721,Q99436,P49720,O43865,P28070,P28074,P20618,P62942
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,190,38,60,117,155
|
264,1056,1293,1686,541,190,2155,1210,117,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,155,802,919,1603,840,1560,1713,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,1.1487726610909024,-0.8570082192801957,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,1.3677940244677216,0.23990727005026555,0.13990709897991843,-0.3173625574811562,0.20678635338280518,-0.28070290912863155,-0.391444589562264,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
Mitotic g1 phase and g1 s transition
| 14
| 67
| 2.181516
| 0.029145
|
P60900,P49721,Q99436,P49720,P28070,P33991,Q14566,P24941,P30153,P14635,O00231,P20618,Q07864,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,271,272,207,140,175,264,117,118,60
|
264,1056,1293,1686,541,2264,2155,1782,759,904,1160,2135,449,1475,175,1210,117,207,1165,1167,1212,1213,1540,762,870,38,543,60,140,269,453,271,910,1592,2250,1651,1074,1433,255,65,696,799,964,125,1263,1320,1175,1078,1222,919,2208,1603,118,1604,840,1559,1177,1560,272,479,567,96,1097,2450,677,1234,515
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-1.0614818199989162,-0.8570082192801957,-0.4665389394864189,0.27281999715468874,0.13990709897991843,-0.03116783582721283,-0.8168470964124629,0.6219616032562505,-0.24429845596012587,1.2319049508681916,-0.06607616153332166,1.5527533004356622,1.0926583185496224,-0.03116783582721283,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.27281999715468874,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,1.421252266939875,0.9498475469241873,0.6219616032562505,0.9498475469241873,0.13990709897991843,-0.3173625574811562,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,-0.20814992181924744,0.9787054273330804,2.2620942289667187,0.3380332804355645,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.06607616153332166,0.13990709897991843,-0.9380658414393885,-0.3173625574811562,1.5527533004356622,-0.3173625574811562,0.20678635338280518,-0.28070290912863155,-0.03116783582721283,-0.28070290912863155,0.9498475469241873,0.5911482301983078,0.4660939704199051,1.757119144304389,0.03794435657742731,-2.510801887820688,0.3703398545461924,-0.06607616153332166,0.5601572877142909
| 2,468
|
Protein methyltransferase activity
| 9
| 17
| 2.170383
| 0.029978
|
Q14166,O60678,Q99873,Q03164,Q86X55,O14744,Q9H9B1,Q9BV86,O60725
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
565,66,604,133,480,475,378,22,63
|
475,66,63,685,1162,1758,133,565,1505,2021,735,480,1720,603,604,22,378
|
0.5911482301983078,2.2157978092752946,2.3080391779465006,0.3380332804355645,-0.03116783582721283,-0.4288655702071363,1.4477948419810402,0.4660939704199051,-0.24429845596012587,-0.6586680831224061,0.3055276524649288,0.5911482301983078,-0.391444589562264,0.43436739361353727,0.43436739361353727,3.6424640725752444,0.7434871462800804
| 2,468
|
Alzheimers disease
| 27
| 74
| 2.160646
| 0.030723
|
P60900,P49720,P16615,P42574,Q13885,O14654,P45880,P04350,P28070,P28072,O43242,Q9NQC3,P28074,P33176,P49721,P68371,P21796,Q9BVA1,P49841,P28482,Q99436,Q15008,P07437,Q9BUF5,Q9NSK0,P20618,O95197
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
125,255,624,626,384,516,404,402,38,543,541,576,60,559,65,201,317,344,337,588,96,479,216,644,111,117,492
|
1056,1293,516,1686,541,492,402,1473,2204,825,2205,216,791,2292,1841,725,624,1210,2006,691,117,317,1167,1212,1213,1540,1250,870,38,543,60,588,1846,559,1425,2250,659,1597,626,1651,404,1074,1930,963,255,65,337,799,964,125,1320,1175,1078,201,920,1265,971,1133,840,1325,384,479,2120,849,96,1097,810,2087,644,344,576,111,1234,999
|
0.03794435657742731,-0.13661678053279144,0.5289862962916688,-0.391444589562264,0.49763272112609636,0.5601572877142909,0.6830652924493599,-0.24429845596012587,-0.9380658414393885,0.20678635338280518,-0.9380658414393885,1.0643882560099536,0.23990727005026555,-1.144972064254425,-0.5044640170129534,0.3055276524649288,0.40245027954676366,-0.06607616153332166,-0.6586680831224061,0.3380332804355645,1.5527533004356622,0.8328806677236555,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,-0.10122447507190645,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,0.43436739361353727,-0.5044640170129534,0.4660939704199051,-0.20814992181924744,-1.0201000011979868,0.3703398545461924,-0.3173625574811562,0.40245027954676366,-0.3542766862538596,0.6830652924493599,0.03794435657742731,-0.5810666157787491,0.10614213666844603,0.9787054273330804,2.2620942289667187,0.8032451697533327,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,1.120785882156883,0.13990709897991843,-0.10122447507190645,0.10614213666844603,0.003504403042592986,0.20678635338280518,-0.13661678053279144,0.7133603055860006,0.5911482301983078,-0.7769319049938614,0.20678635338280518,1.757119144304389,0.03794435657742731,0.23990727005026555,-0.7372632579290869,0.40245027954676366,0.8032451697533327,0.4660939704199051,1.6302362443481822,-0.06607616153332166,0.10614213666844603
| 2,468
|
Cation transmembrane transporter activity
| 10
| 61
| 2.157776
| 0.030945
|
Q9HD20,Q99808,Q70HW3,Q9Y487,P38606,Q93050,P23634,O43772,Q8N4V1,Q13423
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
33,193,4,68,199,13,107,16,94,31
|
16,1736,2332,245,1692,1420,1300,951,2204,1011,1891,1366,953,2307,1534,2292,1586,624,2007,2225,1370,1371,107,1307,2010,625,961,1072,199,2377,874,1127,967,2141,1708,1804,920,31,1507,844,4,94,2120,706,13,639,193,1188,858,1283,1455,1193,1349,1951,33,1462,1575,2067,1732,68,515
|
3.8792061948428853,-0.4288655702071363,-1.2720155125700963,1.007413609708006,-0.391444589562264,-0.20814992181924744,-0.13661678053279144,0.10614213666844603,-0.9380658414393885,0.07215573022457085,-0.5426401305377743,-0.1722571888650981,0.10614213666844603,-1.187079359251964,-0.28070290912863155,-1.144972064254425,-0.3173625574811562,0.40245027954676366,-0.6586680831224061,-0.9789611482255609,-0.1722571888650981,-0.1722571888650981,1.6302362443481822,-0.13661678053279144,-0.6586680831224061,0.40245027954676366,0.10614213666844603,0.03794435657742731,1.120785882156883,-1.4447588451088091,0.17345405363114286,0.003504403042592986,0.10614213666844603,-0.8168470964124629,-0.391444589562264,-0.4665389394864189,0.13990709897991843,3.1217027409278946,-0.24429845596012587,0.20678635338280518,4.412316163110933,1.782167940056854,-0.7769319049938614,0.3380332804355645,4.05578531684179,0.40245027954676366,1.1487726610909024,-0.03116783582721283,0.20678635338280518,-0.10122447507190645,-0.20814992181924744,-0.03116783582721283,-0.13661678053279144,-0.5810666157787491,3.0814059219719945,-0.20814992181924744,-0.28070290912863155,-0.6978417750235022,-0.391444589562264,2.1691433864655685,0.5601572877142909
| 2,468
|
Proteasome
| 7
| 35
| 2.157585
| 0.03096
|
P60900,P49721,Q99436,P49720,P28070,P20618,P28074
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
125,65,96,255,38,117,60
|
264,1056,1293,1686,541,1210,117,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,1603,840,1713,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.3173625574811562,0.20678635338280518,-0.391444589562264,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
S phase
| 24
| 78
| 2.157548
| 0.030963
|
P60900,P49720,Q9Y2S7,P33991,Q14566,O00231,Q9H1A4,Q9UJX4,P28070,P28072,O43242,P28074,P49721,P24941,P11802,P49841,Q29RF7,Q99436,Q15008,P40938,Q9UJX3,Q9Y619,P20618,Q07864
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,255,537,271,272,264,157,556,38,543,541,60,65,207,449,337,223,96,479,220,512,515,117,118
|
264,1056,1293,1686,541,2264,2244,2155,1160,449,1475,1210,117,207,1165,1167,1212,1213,1540,762,870,38,543,60,2073,1018,271,910,1592,1966,829,1593,2250,1428,1314,220,1651,1074,1433,255,65,696,337,799,964,125,1263,1320,1175,1078,919,1603,118,1604,840,1559,1560,272,1027,1713,479,566,223,1089,96,1097,1146,157,2450,1051,676,512,556,677,1234,748,537,515
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-1.0614818199989162,-1.0201000011979868,-0.8570082192801957,-0.03116783582721283,0.6219616032562505,-0.24429845596012587,-0.06607616153332166,1.5527533004356622,1.0926583185496224,-0.03116783582721283,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.27281999715468874,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-0.7372632579290869,0.07215573022457085,0.9498475469241873,0.13990709897991843,-0.3173625574811562,-0.619742816254357,0.20678635338280518,-0.3173625574811562,-1.0201000011979868,-0.20814992181924744,-0.13661678053279144,1.0643882560099536,-0.3542766862538596,0.03794435657742731,-0.20814992181924744,0.9787054273330804,2.2620942289667187,0.3380332804355645,0.8032451697533327,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,0.13990709897991843,-0.3173625574811562,1.5527533004356622,-0.3173625574811562,0.20678635338280518,-0.28070290912863155,-0.28070290912863155,0.9498475469241873,0.07215573022457085,-0.391444589562264,0.5911482301983078,0.4660939704199051,1.0643882560099536,0.03794435657742731,1.757119144304389,0.03794435657742731,0.003504403042592986,1.3677940244677216,-2.510801887820688,0.07215573022457085,0.3703398545461924,0.5601572877142909,0.49763272112609636,0.3703398545461924,-0.06607616153332166,0.3055276524649288,0.5289862962916688,0.5601572877142909
| 2,468
|
transporter
| 20
| 52
| 2.155444
| 0.031127
|
Q567V2,Q92973,Q8N1F7,Q9BRA2,Q9H2D1,O43772,Q99595,Q9HAV4,P54105,P53985,Q8NFH4,O00629,Q99808,Q9HD45,O00410,Q9UI26,Q8TEX9,Q99567,Q6N075,Q9Y619
|
Functions
|
Panther Protein class
|
panther_protein_class
|
0,388,387,531,15,16,27,555,34,546,309,180,193,471,348,243,508,510,368,515
|
348,1467,180,751,947,1413,755,1530,16,1243,756,901,871,590,830,1125,2015,768,1316,2111,1703,546,34,563,801,2141,973,1136,1613,0,368,1719,387,309,1142,508,2191,388,2123,809,510,27,1825,193,531,15,555,471,243,651,893,515
|
0.7734480409672624,-0.24429845596012587,1.204330560625009,0.27281999715468874,0.10614213666844603,-0.20814992181924744,0.27281999715468874,-0.28070290912863155,3.8792061948428853,-0.10122447507190645,0.27281999715468874,0.13990709897991843,0.17345405363114286,0.43436739361353727,0.20678635338280518,0.003504403042592986,-0.6586680831224061,0.27281999715468874,-0.13661678053279144,-0.7769319049938614,-0.391444589562264,0.49763272112609636,3.0611617440095436,0.4660939704199051,0.23990727005026555,-0.8168470964124629,0.10614213666844603,0.003504403042592986,-0.3173625574811562,4.798493942314326,0.7434871462800804,-0.391444589562264,0.7133603055860006,0.8623566262060067,0.003504403042592986,0.5601572877142909,-0.8974146674576974,0.7133603055860006,-0.7769319049938614,0.23990727005026555,0.5601572877142909,3.3583163925414348,-0.4665389394864189,1.1487726610909024,0.5289862962916688,3.8970740362955745,0.49763272112609636,0.6219616032562505,1.0359739469793032,0.40245027954676366,0.17345405363114286,0.5601572877142909
| 2,468
|
Ub specific processing proteases
| 23
| 61
| 2.150902
| 0.031484
|
P60900,P49720,P45974,O00231,P45880,Q8N257,Q9Y4A5,P28070,P28072,O43242,Q9Y3E5,Q93009,P28074,Q9UPU5,P49721,Q8IXI2,P21796,O14964,Q99436,Q15008,Q92890,Q86UV5,P20618
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,255,627,264,404,164,166,38,543,541,443,178,60,195,65,601,317,444,96,479,637,371,117
|
264,1056,1293,1686,444,541,1415,2155,1204,950,725,1210,117,317,1167,1212,1213,1540,870,38,543,60,2250,1651,404,627,1074,255,65,799,1704,964,125,1263,1320,1175,1078,1603,840,1905,1269,1713,479,1860,371,601,164,637,1280,178,1990,96,1097,1460,677,1234,195,1683,999,443,166
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.6219616032562505,0.49763272112609636,-0.20814992181924744,-0.8570082192801957,-0.06607616153332166,0.10614213666844603,0.3055276524649288,-0.06607616153332166,1.5527533004356622,0.8328806677236555,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.6830652924493599,0.40245027954676366,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,-0.391444589562264,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.3173625574811562,0.20678635338280518,-0.5426401305377743,-0.10122447507190645,-0.391444589562264,0.5911482301983078,-0.5044640170129534,0.7434871462800804,0.43436739361353727,1.3138288708840293,0.40245027954676366,-0.10122447507190645,1.2319049508681916,-0.619742816254357,1.757119144304389,0.03794435657742731,-0.20814992181924744,0.3703398545461924,-0.06607616153332166,1.1487726610909024,-0.3542766862538596,0.10614213666844603,0.6525998327464225,1.3138288708840293
| 2,468
|
The role of gtse1 in g2 m progression after g2 checkpoint
| 13
| 47
| 2.146264
| 0.031852
|
P60900,P49721,Q99436,P49720,Q15691,P68371,P28070,Q13885,Q9BVA1,P14635,O00231,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,222,201,38,384,344,175,264,117,60
|
264,1056,1293,1686,541,2155,402,950,904,905,954,175,1210,117,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,201,1603,840,384,1713,479,222,96,1097,644,344,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,0.6830652924493599,0.10614213666844603,0.13990709897991843,0.13990709897991843,0.10614213666844603,1.2319049508681916,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,1.120785882156883,-0.3173625574811562,0.20678635338280518,0.7133603055860006,-0.391444589562264,0.5911482301983078,1.0643882560099536,1.757119144304389,0.03794435657742731,0.40245027954676366,0.8032451697533327,0.3703398545461924,-0.06607616153332166
| 2,468
|
Synthesis of dna
| 13
| 69
| 2.129747
| 0.033192
|
P60900,P49721,Q99436,P49720,P28070,P40938,P33991,Q14566,P24941,P20618,Q07864,Q9H1A4,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,220,271,272,207,117,118,157,60
|
264,1056,1293,1686,541,2264,2155,1160,1475,1210,117,207,1165,1167,1212,1213,1540,762,870,38,543,60,2073,1018,271,910,1592,1966,829,1593,2250,1428,1314,220,1651,1074,1433,255,65,696,799,964,125,1263,1320,1175,1078,919,1603,118,840,1559,1560,272,1713,479,566,96,1097,1146,157,2450,676,512,556,677,1234,537,515
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-1.0614818199989162,-0.8570082192801957,-0.03116783582721283,-0.24429845596012587,-0.06607616153332166,1.5527533004356622,1.0926583185496224,-0.03116783582721283,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.27281999715468874,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-0.7372632579290869,0.07215573022457085,0.9498475469241873,0.13990709897991843,-0.3173625574811562,-0.619742816254357,0.20678635338280518,-0.3173625574811562,-1.0201000011979868,-0.20814992181924744,-0.13661678053279144,1.0643882560099536,-0.3542766862538596,0.03794435657742731,-0.20814992181924744,0.9787054273330804,2.2620942289667187,0.3380332804355645,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,0.13990709897991843,-0.3173625574811562,1.5527533004356622,0.20678635338280518,-0.28070290912863155,-0.28070290912863155,0.9498475469241873,-0.391444589562264,0.5911482301983078,0.4660939704199051,1.757119144304389,0.03794435657742731,0.003504403042592986,1.3677940244677216,-2.510801887820688,0.3703398545461924,0.5601572877142909,0.49763272112609636,0.3703398545461924,-0.06607616153332166,0.5289862962916688,0.5601572877142909
| 2,468
|
Increased serum pyruvate
| 6
| 24
| 2.128092
| 0.033329
|
Q9Y6M9,Q70HW3,Q5JRX3,O75306,Q9BWD1,O96000
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
160,4,145,80,17,123
|
162,2366,80,2305,290,123,1889,1116,1535,1070,542,587,2249,1426,1434,1485,497,1442,145,4,17,1679,783,160
|
1.3138288708840293,-1.401215472847145,1.9545829828587022,-1.187079359251964,0.8916750939887781,1.5005137733127836,-0.5426401305377743,0.003504403042592986,-0.28070290912863155,0.03794435657742731,0.49763272112609636,0.43436739361353727,-1.0201000011979868,-0.20814992181924744,-0.20814992181924744,-0.24429845596012587,0.5601572877142909,-0.20814992181924744,1.421252266939875,4.412316163110933,3.843326965900602,-0.3542766862538596,0.27281999715468874,1.3408755334440563
| 2,468
|
Abdominal pain
| 17
| 68
| 2.114908
| 0.034438
|
Q9Y4P3,Q70HW3,P43246,P52701,P14174,P42892,Q14566,Q14C86,P40763,Q8NFH4,O43707,Q9NZ08,Q9BZK7,P23786,Q96BN8,Q14108,Q13423
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
196,4,254,292,198,75,272,47,141,309,244,152,56,89,225,30,31
|
244,686,950,2290,2156,2464,1746,826,1749,1785,198,1536,303,542,1589,2226,89,1928,1123,1425,829,423,660,1967,141,2335,75,254,963,2110,292,801,770,771,877,1081,456,1806,973,1324,31,30,272,1612,47,976,1564,1814,2023,1139,4,387,309,671,2358,705,1624,225,992,56,1192,2319,1833,152,1106,1999,196,2038
|
1.007413609708006,0.3380332804355645,0.10614213666844603,-1.144972064254425,-0.8570082192801957,-3.8054916366383664,-0.4288655702071363,0.20678635338280518,-0.4288655702071363,-0.4665389394864189,1.120785882156883,-0.28070290912863155,0.8623566262060067,0.49763272112609636,-0.3173625574811562,-0.9789611482255609,1.8319466790670544,-0.5810666157787491,0.003504403042592986,-0.20814992181924744,0.20678635338280518,0.6525998327464225,0.3703398545461924,-0.619742816254357,1.421252266939875,-1.2720155125700963,2.0029346640137495,0.9787054273330804,0.10614213666844603,-0.7769319049938614,0.8916750939887781,0.23990727005026555,0.27281999715468874,0.27281999715468874,0.17345405363114286,0.03794435657742731,0.6219616032562505,-0.4665389394864189,0.10614213666844603,-0.13661678053279144,3.1217027409278946,3.181676304646078,0.9498475469241873,-0.3173625574811562,2.5985360100891364,0.10614213666844603,-0.28070290912863155,-0.4665389394864189,-0.6586680831224061,0.003504403042592986,4.412316163110933,0.7133603055860006,0.8623566262060067,0.3703398545461924,-1.357910106482782,0.3380332804355645,-0.3173625574811562,1.0643882560099536,0.10614213666844603,2.4438277655987086,-0.03116783582721283,-1.187079359251964,-0.4665389394864189,1.3945857941684383,0.03794435657742731,-0.619742816254357,1.1487726610909024,-0.6586680831224061
| 2,468
|
Degradation of dvl
| 8
| 37
| 2.105309
| 0.035264
|
P60900,P49721,Q99436,P49720,P28070,Q13618,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,211,117,60
|
264,1056,1293,1686,541,2155,1210,117,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,1603,840,211,1713,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.3173625574811562,0.20678635338280518,1.0926583185496224,-0.391444589562264,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
Abnormality of cranial sutures
| 25
| 70
| 2.100282
| 0.035704
|
Q00577,Q32P28,P30153,P40763,P61978,Q96AY3,O00469,P46821,Q92785,O95831,Q93009,O75718,Q15436,Q69YQ0,Q9Y487,P38606,Q15813,Q12756,Q8NCH0,Q68CP9,O75844,Q08J23,Q8IYI6,Q8NC56,Q9Y619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
499,385,140,141,406,286,400,544,294,290,178,418,55,187,68,199,459,341,90,351,476,109,239,373,515
|
400,1685,817,1470,1157,1579,1740,418,476,290,1206,867,1160,792,1587,1480,1788,1370,1249,1539,2179,1965,1017,588,140,1310,199,2045,141,694,544,873,2138,1851,1126,697,406,1759,730,499,2057,109,341,1389,55,459,1033,385,1183,351,187,2340,884,239,373,90,294,637,178,1624,286,990,572,2033,2067,748,1734,68,1292,515
|
0.6830652924493599,-0.391444589562264,0.20678635338280518,-0.24429845596012587,-0.03116783582721283,-0.3173625574811562,-0.4288655702071363,0.6525998327464225,0.5911482301983078,0.8916750939887781,-0.06607616153332166,0.17345405363114286,-0.03116783582721283,0.23990727005026555,-0.3173625574811562,-0.24429845596012587,-0.4665389394864189,-0.1722571888650981,-0.10122447507190645,-0.28070290912863155,-0.8974146674576974,-0.619742816254357,0.07215573022457085,0.43436739361353727,1.421252266939875,-0.13661678053279144,1.120785882156883,-0.6978417750235022,1.421252266939875,0.3380332804355645,0.49763272112609636,0.17345405363114286,-0.8168470964124629,-0.5044640170129534,0.003504403042592986,0.3380332804355645,0.6830652924493599,-0.4288655702071363,0.3055276524649288,0.5601572877142909,-0.6978417750235022,1.6302362443481822,0.8032451697533327,-0.1722571888650981,2.4438277655987086,0.6219616032562505,0.07215573022457085,0.7133603055860006,-0.03116783582721283,0.7734480409672624,1.1766203371738273,-1.2720155125700963,0.17345405363114286,1.0359739469793032,0.7434871462800804,1.8319466790670544,0.8916750939887781,0.40245027954676366,1.2319049508681916,-0.3173625574811562,0.9208380784964595,0.10614213666844603,0.4660939704199051,-0.6586680831224061,-0.6978417750235022,0.3055276524649288,-0.391444589562264,2.1691433864655685,-0.10122447507190645,0.5601572877142909
| 2,468
|
Regulation of ras by gaps
| 9
| 38
| 2.09914
| 0.035805
|
P60900,P49721,Q99436,P49720,P28070,Q13618,O00231,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,211,264,117,60
|
264,1056,1293,1686,541,2155,1210,117,303,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,1603,840,211,1713,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,-0.06607616153332166,1.5527533004356622,0.8623566262060067,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.3173625574811562,0.20678635338280518,1.0926583185496224,-0.391444589562264,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
G1 s dna damage checkpoints
| 8
| 38
| 2.097643
| 0.035937
|
P60900,P49721,Q99436,P49720,P28070,P24941,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,207,117,60
|
264,1056,1293,1686,541,2155,950,1210,117,207,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,1603,840,1713,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,0.10614213666844603,-0.06607616153332166,1.5527533004356622,1.0926583185496224,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.3173625574811562,0.20678635338280518,-0.391444589562264,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
Apc c mediated degradation of cell cycle proteins
| 10
| 49
| 2.097394
| 0.035959
|
P60900,P49721,Q99436,P49720,P28070,P24941,P14635,P20618,Q9H1A4,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,207,175,117,157,60
|
264,1056,1293,1686,541,1111,788,2155,904,175,1210,117,207,1167,1212,1213,1540,870,38,543,60,1018,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,919,1603,840,1560,1713,479,566,96,1097,157,676,512,556,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,0.003504403042592986,0.23990727005026555,-0.8570082192801957,0.13990709897991843,1.2319049508681916,-0.06607616153332166,1.5527533004356622,1.0926583185496224,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,0.07215573022457085,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,0.13990709897991843,-0.3173625574811562,0.20678635338280518,-0.28070290912863155,-0.391444589562264,0.5911482301983078,0.4660939704199051,1.757119144304389,0.03794435657742731,1.3677940244677216,0.3703398545461924,0.5601572877142909,0.49763272112609636,0.3703398545461924,-0.06607616153332166
| 2,468
|
Inflammatory response
| 11
| 48
| 2.092806
| 0.036366
|
P60900,P09429,P28070,P14174,Q9BQE5,P42785,P00813,P40763,Q96BN8,Q8IV08,Q9Y263
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
125,217,38,198,14,209,18,141,225,121,228
|
1774,1155,1243,518,18,1246,686,1694,1960,217,2106,198,1069,1167,246,38,452,1751,1169,2045,141,1597,209,963,1702,125,2185,1384,1557,731,1442,1863,844,775,121,1672,225,641,1045,886,1627,2193,1873,14,646,1288,679,228
|
-0.4665389394864189,-0.03116783582721283,-0.10122447507190645,0.5289862962916688,3.8253149596469553,-0.10122447507190645,0.3380332804355645,-0.391444589562264,-0.619742816254357,1.0643882560099536,-0.7769319049938614,1.120785882156883,0.03794435657742731,-0.03116783582721283,1.007413609708006,2.8550887102218057,0.6219616032562505,-0.4288655702071363,-0.03116783582721283,-0.6978417750235022,1.421252266939875,-0.3173625574811562,1.0926583185496224,0.10614213666844603,-0.391444589562264,1.474214893902258,-0.8974146674576974,-0.1722571888650981,-0.28070290912863155,0.3055276524649288,-0.20814992181924744,-0.5044640170129534,0.20678635338280518,0.27281999715468874,1.5266928073906822,-0.3542766862538596,1.0643882560099536,0.40245027954676366,0.07215573022457085,0.17345405363114286,-0.3173625574811562,-0.8974146674576974,-0.5044640170129534,4.038333838427878,0.40245027954676366,-0.10122447507190645,0.3703398545461924,1.0643882560099536
| 2,468
|
Abnormal circulating carbohydrate concentration
| 6
| 28
| 2.083701
| 0.037187
|
Q9Y6M9,Q70HW3,Q5JRX3,O75306,Q9BWD1,O96000
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
160,4,145,80,17,123
|
162,2366,80,2305,290,123,1889,1116,1535,1070,542,587,2249,1251,1426,1434,1076,1485,497,1442,145,4,1185,17,1679,783,1355,160
|
1.3138288708840293,-1.401215472847145,1.9545829828587022,-1.187079359251964,0.8916750939887781,1.5005137733127836,-0.5426401305377743,0.003504403042592986,-0.28070290912863155,0.03794435657742731,0.49763272112609636,0.43436739361353727,-1.0201000011979868,-0.10122447507190645,-0.20814992181924744,-0.20814992181924744,0.03794435657742731,-0.24429845596012587,0.5601572877142909,-0.20814992181924744,1.421252266939875,4.412316163110933,-0.03116783582721283,3.843326965900602,-0.3542766862538596,0.27281999715468874,-0.13661678053279144,1.3408755334440563
| 2,468
|
Downstream signaling events of b cell receptor bcr
| 8
| 39
| 2.07442
| 0.03804
|
P60900,P49721,Q99436,P49720,P28070,P28074,P20618,P62942
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,60,117,155
|
264,1056,1293,1686,541,2155,1210,117,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,155,919,1603,840,1560,1713,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,1.3677940244677216,0.13990709897991843,-0.3173625574811562,0.20678635338280518,-0.28070290912863155,-0.391444589562264,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
Autoimmunity
| 12
| 26
| 2.067361
| 0.0387
|
Q9Y3Z3,P53621,Q92890,P14174,Q969U7,Q96J02,P00813,P40763,P50851,P42224,O60934,Q15437
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
394,545,637,198,529,641,18,141,86,561,583,159
|
583,1693,18,622,1014,198,1539,1306,1590,141,561,963,86,545,1126,1077,771,1974,159,1037,637,529,641,858,941,394
|
0.43436739361353727,-0.391444589562264,3.8253149596469553,0.40245027954676366,0.07215573022457085,1.120785882156883,-0.28070290912863155,-0.13661678053279144,-0.3173625574811562,1.421252266939875,0.4660939704199051,0.10614213666844603,1.8813074269920262,0.49763272112609636,0.003504403042592986,0.03794435657742731,0.27281999715468874,-0.619742816254357,1.3408755334440563,0.07215573022457085,0.40245027954676366,0.5289862962916688,0.40245027954676366,0.20678635338280518,0.13990709897991843,0.7133603055860006
| 2,468
|
Interleukin 1 family signaling
| 9
| 43
| 2.050868
| 0.04028
|
P60900,P49721,Q99436,P49720,P09429,P28070,P40763,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,217,38,141,117,60
|
264,1056,1293,1686,541,2155,217,1210,117,1167,1212,1213,1540,870,38,543,60,2250,141,1651,1074,255,65,799,964,125,1656,1263,1320,1175,1078,919,1265,1977,1603,840,1560,1713,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,1.0643882560099536,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,1.421252266939875,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.3542766862538596,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,0.13990709897991843,-0.10122447507190645,-0.619742816254357,-0.3173625574811562,0.20678635338280518,-0.28070290912863155,-0.391444589562264,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
Response to oxygen levels
| 18
| 52
| 2.046448
| 0.040712
|
Q99808,Q9Y487,Q8N511,P38606,Q96EB6,P30519,O95831,Q8IXJ6,O75306,P00813,P11166,P55061,O43707,Q9NQ88,P21359,P55786,P52789,Q9Y4P3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
193,68,99,199,172,44,290,110,80,18,174,182,244,414,303,26,338,196
|
1527,400,244,80,290,1009,18,1206,1246,950,951,2005,867,2106,174,1843,1788,303,2226,44,1310,1426,199,1597,626,1897,963,1485,338,182,26,967,1550,698,1085,2083,734,110,99,1143,2191,2085,2359,172,1674,2124,193,414,2411,68,1290,196
|
-0.28070290912863155,0.6830652924493599,1.007413609708006,1.9545829828587022,0.8916750939887781,0.07215573022457085,3.8253149596469553,-0.06607616153332166,-0.10122447507190645,0.10614213666844603,0.10614213666844603,-0.6586680831224061,0.17345405363114286,-0.7769319049938614,1.2319049508681916,-0.5044640170129534,-0.4665389394864189,0.8623566262060067,-0.9789611482255609,2.6420354190598694,-0.13661678053279144,-0.20814992181924744,1.120785882156883,-0.3173625574811562,0.40245027954676366,-0.5426401305377743,0.10614213666844603,-0.24429845596012587,0.8032451697533327,1.204330560625009,3.416142107313884,0.10614213666844603,-0.28070290912863155,0.3380332804355645,0.03794435657742731,-0.7372632579290869,0.3055276524649288,1.6302362443481822,1.7319626002078956,0.003504403042592986,-0.8974146674576974,-0.7372632579290869,-1.357910106482782,1.259345097312692,-0.3542766862538596,-0.7769319049938614,1.1487726610909024,0.6830652924493599,-1.666027641363195,2.1691433864655685,-0.10122447507190645,1.1487726610909024
| 2,468
|
Regulation of runx3 expression and activity
| 7
| 35
| 2.04507
| 0.040848
|
P60900,P49721,Q99436,P49720,P28070,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,117,60
|
264,1056,1293,1686,541,2155,1210,117,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,1603,840,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.3173625574811562,0.20678635338280518,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
Splenomegaly
| 9
| 68
| 2.042731
| 0.041079
|
P28070,Q15392,P07602,P00813,P11166,P50851,Q9NZ08,Q14108,Q15437
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
38,40,72,18,174,86,152,30,159
|
1155,1685,751,1924,1364,1689,821,1298,1693,18,1206,686,1299,1582,950,1839,1064,2156,72,2333,174,1749,1302,1785,1014,198,2136,1209,1069,1370,1539,1589,1697,38,1698,1590,271,961,660,1427,963,86,873,2138,1126,1438,1219,2266,408,2415,30,1028,40,159,1137,1085,369,637,529,638,707,1991,641,1949,858,1194,152,939
|
-0.03116783582721283,-0.391444589562264,0.27281999715468874,-0.5810666157787491,-0.1722571888650981,-0.391444589562264,0.20678635338280518,-0.13661678053279144,-0.391444589562264,3.8253149596469553,-0.06607616153332166,0.3380332804355645,-0.13661678053279144,-0.3173625574811562,0.10614213666844603,-0.5044640170129534,0.03794435657742731,-0.8570082192801957,2.0269638105009165,-1.2720155125700963,1.2319049508681916,-0.4288655702071363,-0.13661678053279144,-0.4665389394864189,0.07215573022457085,1.120785882156883,-0.8168470964124629,-0.06607616153332166,0.03794435657742731,-0.1722571888650981,-0.28070290912863155,-0.3173625574811562,-0.391444589562264,2.8550887102218057,-0.391444589562264,-0.3173625574811562,0.9498475469241873,0.10614213666844603,0.3703398545461924,-0.20814992181924744,0.10614213666844603,1.8813074269920262,0.17345405363114286,-0.8168470964124629,0.003504403042592986,-0.20814992181924744,-0.06607616153332166,-1.0614818199989162,0.6830652924493599,-1.7109882266710317,3.181676304646078,0.07215573022457085,2.813054466119539,1.3408755334440563,0.003504403042592986,0.03794435657742731,0.7434871462800804,0.40245027954676366,0.5289862962916688,0.40245027954676366,0.3380332804355645,-0.619742816254357,0.40245027954676366,-0.5810666157787491,0.20678635338280518,-0.03116783582721283,1.3945857941684383,0.13990709897991843
| 2,468
|
Tcf dependent signaling in response to wnt
| 14
| 55
| 2.042722
| 0.04108
|
P60900,Q8N257,Q9Y4A5,P49720,P49721,Q99436,P28070,P30153,Q13618,O00231,P30154,P49841,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,164,166,255,65,96,38,140,211,264,269,337,117,60
|
264,1056,1293,1686,947,541,2155,1210,691,117,1167,1212,1213,1540,870,38,543,60,140,269,1425,2250,1651,1074,1930,255,65,337,1798,799,964,125,1263,1320,1175,1078,2379,1492,1603,840,1177,211,1179,1713,479,2021,2023,164,96,1097,354,677,1234,1683,166
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.10614213666844603,0.49763272112609636,-0.8570082192801957,-0.06607616153332166,0.3380332804355645,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,1.421252266939875,0.9498475469241873,-0.20814992181924744,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,-0.5810666157787491,0.9787054273330804,2.2620942289667187,0.8032451697533327,-0.4665389394864189,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-1.4447588451088091,-0.24429845596012587,-0.3173625574811562,0.20678635338280518,-0.03116783582721283,1.0926583185496224,-0.03116783582721283,-0.391444589562264,0.5911482301983078,-0.6586680831224061,-0.6586680831224061,1.3138288708840293,1.757119144304389,0.03794435657742731,0.7734480409672624,0.3703398545461924,-0.06607616153332166,-0.3542766862538596,1.3138288708840293
| 2,468
|
Abnormal paranasal sinus morphology
| 6
| 18
| 2.027033
| 0.042659
|
P28070,Q86Y56,P57076,P00813,P50851,P21359
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
38,386,142,18,86,303
|
1055,1685,583,1693,18,1299,826,1249,303,38,86,142,771,2413,463,386,858,945
|
0.03794435657742731,-0.391444589562264,0.43436739361353727,-0.391444589562264,3.8253149596469553,-0.13661678053279144,0.20678635338280518,-0.10122447507190645,0.8623566262060067,2.8550887102218057,1.8813074269920262,1.421252266939875,0.27281999715468874,-1.7109882266710317,0.6219616032562505,0.7133603055860006,0.20678635338280518,0.13990709897991843
| 2,468
|
Hedgehog ligand biogenesis
| 8
| 39
| 2.019282
| 0.043458
|
P60900,P49721,Q99436,P49720,P28070,P20618,Q9UBV2,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,117,251,60
|
264,1056,1293,1686,541,2155,867,1210,117,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,1598,125,1263,1320,1175,1078,1603,840,1713,479,96,1097,251,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,0.17345405363114286,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,-0.3173625574811562,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.3173625574811562,0.20678635338280518,-0.391444589562264,0.5911482301983078,1.757119144304389,0.03794435657742731,1.007413609708006,0.3703398545461924,-0.06607616153332166
| 2,468
|
Negative regulation of notch4 signaling
| 8
| 39
| 2.008064
| 0.044637
|
P60900,P49721,Q99436,P49720,P28070,O00231,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,264,117,60
|
264,1056,1293,1686,541,2155,1210,117,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,1492,919,1603,840,1560,479,96,1097,677,1234,300
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.24429845596012587,0.13990709897991843,-0.3173625574811562,0.20678635338280518,-0.28070290912863155,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166,0.8916750939887781
| 2,468
|
Mitochondrial transport
| 16
| 69
| 1.996678
| 0.04586
|
P30536,Q9NS69,Q96EK5,P23786,Q5JRX3,O95831,O43772,O14737,Q3ZCQ8,P52789,O75964,Q10713,P49841,P49257,P55786,Q99595
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,101,137,89,145,290,16,173,81,338,245,408,337,57,26,27
|
681,173,1295,755,16,1579,1886,2332,245,1204,1007,493,290,1533,950,2204,1011,905,1585,1961,2292,691,89,1307,2010,1846,1252,64,960,1072,1897,404,2377,1899,57,1217,337,2378,338,26,1127,427,408,1613,1860,1031,1813,81,1182,145,2340,884,1396,601,1446,137,886,1627,27,2089,1191,2217,101,675,1354,1355,893,2220,786
|
0.3380332804355645,1.2319049508681916,-0.13661678053279144,0.27281999715468874,3.8792061948428853,-0.3173625574811562,-0.5426401305377743,-1.2720155125700963,1.007413609708006,-0.06607616153332166,0.07215573022457085,0.5601572877142909,0.8916750939887781,-0.28070290912863155,0.10614213666844603,-0.9380658414393885,0.07215573022457085,0.13990709897991843,-0.3173625574811562,-0.619742816254357,-1.144972064254425,0.3380332804355645,1.8319466790670544,-0.13661678053279144,-0.6586680831224061,-0.5044640170129534,-0.10122447507190645,2.2620942289667187,0.10614213666844603,0.03794435657742731,-0.5426401305377743,0.6830652924493599,-1.4447588451088091,-0.5426401305377743,2.3988998665849484,-0.06607616153332166,0.8032451697533327,-1.4447588451088091,0.8032451697533327,3.416142107313884,0.003504403042592986,0.6525998327464225,0.6830652924493599,-0.3173625574811562,-0.5044640170129534,0.07215573022457085,-0.4665389394864189,1.9545829828587022,-0.03116783582721283,1.421252266939875,-1.2720155125700963,0.17345405363114286,-0.1722571888650981,0.43436739361353727,-0.20814992181924744,1.4477948419810402,0.17345405363114286,-0.3173625574811562,3.3583163925414348,-0.7372632579290869,-0.03116783582721283,-0.9380658414393885,1.7319626002078956,0.3703398545461924,-0.13661678053279144,-0.13661678053279144,0.17345405363114286,-0.9380658414393885,0.27281999715468874
| 2,468
|
Scf skp2 mediated degradation of p27 p21
| 8
| 39
| 1.993389
| 0.046219
|
P60900,P49721,Q99436,P49720,P28070,P24941,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,207,117,60
|
264,1056,1293,1686,541,2155,449,1210,117,207,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,919,1603,840,1560,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,0.6219616032562505,-0.06607616153332166,1.5527533004356622,1.0926583185496224,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,0.13990709897991843,-0.3173625574811562,0.20678635338280518,-0.28070290912863155,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
Cytoprotection by hmox1
| 11
| 59
| 1.991271
| 0.046451
|
P60900,P49721,Q99436,P49720,P28070,P30519,P40763,Q13618,P20618,Q9BZK7,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,44,141,211,117,56,60
|
264,1056,2242,1293,1686,541,683,2155,2412,1420,2106,689,1534,1586,868,1210,691,117,2225,1167,1212,1213,1540,870,38,543,60,44,1169,2250,141,1216,1651,1074,255,65,799,1653,964,125,1263,1320,1175,1078,919,1603,840,1560,211,1713,479,480,1512,991,96,1097,56,677,1234
|
0.9498475469241873,0.03794435657742731,-1.0201000011979868,-0.13661678053279144,-0.391444589562264,0.49763272112609636,0.3380332804355645,-0.8570082192801957,-1.7109882266710317,-0.20814992181924744,-0.7769319049938614,0.3380332804355645,-0.28070290912863155,-0.3173625574811562,0.17345405363114286,-0.06607616153332166,0.3380332804355645,1.5527533004356622,-0.9789611482255609,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,2.6420354190598694,-0.03116783582721283,-1.0201000011979868,1.421252266939875,-0.06607616153332166,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,-0.3542766862538596,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,0.13990709897991843,-0.3173625574811562,0.20678635338280518,-0.28070290912863155,1.0926583185496224,-0.391444589562264,0.5911482301983078,0.5911482301983078,-0.24429845596012587,0.10614213666844603,1.757119144304389,0.03794435657742731,2.4438277655987086,0.3703398545461924,-0.06607616153332166
| 2,468
|
In utero embryonic development
| 26
| 75
| 1.988841
| 0.046719
|
P67809,P61201,P43246,Q96EK5,Q6PD62,O43772,Q14344,P00813,Q96AY3,Q8IWS0,Q92541,P14635,Q9NQC3,Q9BZK7,Q99873,Q9NZN8,Q13618,P31350,P35579,O60934,P23786,Q9NR09,Q9HCK8,Q08J23,Q13895,O75312
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
498,131,254,137,528,16,525,18,286,285,436,175,576,56,604,473,211,453,335,583,89,93,354,109,501,490
|
1108,16,683,583,490,1007,1205,18,950,1960,1064,175,1587,869,1423,89,1482,588,1252,453,1425,335,254,1651,1255,1126,131,2161,802,498,1936,1265,109,2337,2311,2210,1324,211,501,525,2164,1667,2436,1138,1715,979,805,2270,1619,528,1622,1276,285,1512,436,1723,286,137,991,604,1146,56,1049,354,1350,576,93,938,473,1463,652,945,2097,1577,2365
|
0.003504403042592986,3.8792061948428853,0.3380332804355645,0.43436739361353727,0.5601572877142909,0.07215573022457085,-0.06607616153332166,3.8253149596469553,0.10614213666844603,-0.619742816254357,0.03794435657742731,1.2319049508681916,-0.3173625574811562,0.17345405363114286,-0.20814992181924744,1.8319466790670544,-0.24429845596012587,0.43436739361353727,-0.10122447507190645,0.6219616032562505,-0.20814992181924744,0.8032451697533327,0.9787054273330804,-0.3542766862538596,-0.10122447507190645,0.003504403042592986,1.4477948419810402,-0.8570082192801957,0.23990727005026555,0.5601572877142909,-0.5810666157787491,-0.10122447507190645,1.6302362443481822,-1.2720155125700963,-1.187079359251964,-0.9380658414393885,-0.13661678053279144,1.0926583185496224,0.5601572877142909,0.5289862962916688,-0.8570082192801957,-0.3542766862538596,-2.1261256626172185,0.003504403042592986,-0.391444589562264,0.10614213666844603,0.23990727005026555,-1.0614818199989162,-0.3173625574811562,0.5289862962916688,-0.3173625574811562,-0.10122447507190645,0.9208380784964595,-0.24429845596012587,0.6525998327464225,-0.391444589562264,0.9208380784964595,1.4477948419810402,0.10614213666844603,0.43436739361353727,0.003504403042592986,2.4438277655987086,0.07215573022457085,0.7734480409672624,-0.13661678053279144,0.4660939704199051,1.8071100900408057,0.13990709897991843,0.6219616032562505,-0.20814992181924744,0.40245027954676366,0.13990709897991843,-0.7372632579290869,-0.28070290912863155,-1.357910106482782
| 2,468
|
Interleukin 1 signaling
| 8
| 41
| 1.978083
| 0.047919
|
P60900,P49721,Q99436,P49720,P09429,P28070,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,217,38,117,60
|
264,1056,1293,1686,541,2155,217,1210,117,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1656,1263,1320,1175,1078,919,1265,1603,840,1560,1713,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,1.0643882560099536,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.3542766862538596,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,0.13990709897991843,-0.10122447507190645,-0.3173625574811562,0.20678635338280518,-0.28070290912863155,-0.391444589562264,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
Synthesis of active ubiquitin roles of e1 and e2 enzymes
| 6
| 10
| 1.973635
| 0.048423
|
Q16763,A0AVT1,Q93009,Q96BN8,P68036,P49427
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
566,37,178,225,427,405
|
37,1306,627,405,1600,427,566,1280,178,225
|
2.9589633825131183,-0.13661678053279144,0.40245027954676366,0.6830652924493599,-0.3173625574811562,0.6525998327464225,0.4660939704199051,-0.10122447507190645,1.2319049508681916,1.0643882560099536
| 2,468
|
Degradation of axin
| 7
| 36
| 1.966109
| 0.049286
|
P60900,P49721,Q99436,P49720,P28070,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,117,60
|
264,1056,1293,1686,541,2155,1210,117,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,1603,840,1713,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.3173625574811562,0.20678635338280518,-0.391444589562264,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
Cross presentation of soluble exogenous antigens endosomes
| 7
| 36
| 1.966109
| 0.049286
|
P60900,P49721,Q99436,P49720,P28070,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,117,60
|
264,1056,1293,1686,541,2155,1210,117,1167,1212,1213,1540,870,38,543,60,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,1603,840,1713,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,-0.06607616153332166,1.5527533004356622,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.3173625574811562,0.20678635338280518,-0.391444589562264,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
Transcriptional regulation by runx3
| 7
| 39
| 1.96577
| 0.049325
|
P60900,P49721,Q99436,P49720,P28070,P20618,P28074
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
125,65,96,255,38,117,60
|
264,1056,1293,1686,541,2155,950,1210,117,1211,1167,1212,1213,1540,870,38,543,60,1425,2250,1651,1074,255,65,799,964,125,1263,1320,1175,1078,1603,840,1441,479,96,1097,677,1234
|
0.9498475469241873,0.03794435657742731,-0.13661678053279144,-0.391444589562264,0.49763272112609636,-0.8570082192801957,0.10614213666844603,-0.06607616153332166,1.5527533004356622,-0.06607616153332166,-0.03116783582721283,-0.06607616153332166,-0.06607616153332166,-0.28070290912863155,0.17345405363114286,2.8550887102218057,0.49763272112609636,2.3536390018116236,-0.20814992181924744,-1.0201000011979868,-0.3542766862538596,0.03794435657742731,0.9787054273330804,2.2620942289667187,0.23990727005026555,0.10614213666844603,1.474214893902258,-0.10122447507190645,-0.13661678053279144,-0.03116783582721283,0.03794435657742731,-0.3173625574811562,0.20678635338280518,-0.20814992181924744,0.5911482301983078,1.757119144304389,0.03794435657742731,0.3703398545461924,-0.06607616153332166
| 2,468
|
Anal atresia
| 8
| 16
| 3.302582
| 0.000958
|
O60934,Q86W42,P53701,P21964,Q96ST3,P36776,O15344,P29372
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
416,1,271,177,466,371,153,221
|
153,1205,416,177,221,371,1141,271,1131,1,1296,1056,1019,466,523,1030
|
1.448587878163448,-0.14372513071509743,0.790742766695202,1.374854179758199,1.21562356866839,0.8752502285881516,-0.06255412202545008,1.1058224313459646,-0.0509288556690046,4.159211210224238,-0.22452414065779183,0.007304838930220447,0.04232941136084772,0.7064830339147586,0.6224784502181606,0.030647621232357772
| 2,198
|
Abnormality of the nail
| 37
| 86
| 3.269899
| 0.001076
|
Q14574,Q9Y4R8,Q99575,Q969G3,P21281,P46109,P53701,P28482,O75844,Q06136,P52732,P15924,Q6NW34,Q9Y4A5,O60341,P04066,P42892,Q14739,Q7Z6Z7,O95453,Q9H2M9,P11172,Q9H1A4,Q03001,Q96ST3,Q15738,P51812,O96028,O14802,Q12756,O60832,Q9UQ13,P17612,Q9Y487,Q96T60,Q9Y619,P51149
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
133,395,138,141,268,142,271,154,409,32,291,419,42,433,434,51,56,57,184,450,73,461,210,82,466,88,468,467,220,224,353,236,362,121,250,251,378
|
1033,220,434,1205,353,1919,1564,1127,1302,409,1516,450,467,2038,1517,51,1206,1584,1420,1560,923,461,728,419,851,362,1399,1751,268,1406,1693,1469,154,1271,976,1069,56,142,378,1040,468,291,271,1227,612,2022,1909,1798,82,32,606,1839,224,1462,1938,133,1074,57,510,2052,569,858,88,1613,1738,42,184,624,479,141,1451,466,1786,250,138,210,73,1532,1150,1582,1812,236,121,433,395,251
|
0.01897275015834451,1.21562356866839,0.7425635484221493,-0.14372513071509743,0.8994397317643743,-1.0195261743694377,-0.5097668221987273,-0.0509288556690046,-0.23603547605020936,0.8028002615442877,-0.45316226325665193,0.7185046953012093,0.6944665788491569,-1.3111052120283924,-0.45316226325665193,2.15610542472213,-0.14372513071509743,-0.5436149050829462,-0.3506990843889215,-0.4984648064973515,0.12429235183705688,0.7064830339147586,0.3483617649744746,0.7786903268114149,0.19480462663768106,0.8873425337211313,-0.3278331884567082,-0.7559158239914561,1.1058224313459646,-0.3392704044038925,-0.6781075616522251,-0.3963271591569024,1.448587878163448,-0.201477670725542,0.07741589559046182,-0.004356071152005715,2.118568547897983,1.4978266247649157,0.8631628360234447,0.01897275015834451,0.6944665788491569,1.0449808182833955,1.1058224313459646,-0.15529101731407544,0.4910059425085586,-1.2574624605043063,-0.9977301401189327,-0.8332862872584502,1.8442815918897568,2.470108172021455,0.5029302870993266,-0.8882982890514788,1.21562356866839,-0.3849332683480805,-1.0412932184918569,1.5347986112370997,-0.004356071152005715,2.118568547897983,0.6344631896532734,-1.364598870559014,0.550683575669592,0.19480462663768106,1.8194344922439065,-0.5773742830804047,-0.7337308614047359,2.29400692469223,1.3625799253617583,0.47908724113358925,0.6824553525082887,1.5101465543310568,-0.37353058139437023,0.7064830339147586,-0.8001792756563424,1.154578002870311,1.5224705542389625,1.2645396465162522,1.906464628112259,-0.4645019164518892,-0.07417212819256301,-0.5323419537246571,-0.84430512391688,1.1911919761542025,1.608851421298922,0.7546006963417613,0.8390028680664574,1.154578002870311
| 2,198
|
High anterior hairline
| 12
| 17
| 3.018077
| 0.002544
|
Q86W42,Q5H8A4,Q9BZK7,Q6NW34,Q8N3U4,Q16851,P21281,Q96ST3,O60341,Q92643,O15344,P29372
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,388,299,42,298,172,268,466,434,180,153,221
|
153,434,1516,467,268,221,612,172,388,42,1,298,180,466,1786,299,1532
|
1.448587878163448,0.7425635484221493,-0.45316226325665193,0.6944665788491569,1.1058224313459646,1.21562356866839,0.4910059425085586,1.3994153412934467,0.8510803758517015,2.29400692469223,4.159211210224238,1.032826380766771,1.374854179758199,0.7064830339147586,-0.8001792756563424,1.032826380766771,-0.4645019164518892
| 2,198
|
Hyperpigmentation of the skin
| 24
| 66
| 2.967531
| 0.003002
|
P21281,P53701,Q9Y2U8,P28482,O75844,O60934,Q06136,Q7Z392,Q7Z6Z7,Q14739,P55011,Q9BPU6,Q15645,O75531,P04062,O95453,Q9H1A4,Q96ST3,Q06124,O60832,Q15437,Q6PGP7,Q9UQ13,O96019
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
268,271,408,154,409,416,32,296,184,57,60,444,192,196,69,450,210,466,223,353,100,484,236,116
|
1525,1048,482,353,416,196,409,450,116,1517,69,1584,1420,813,704,923,816,851,1399,268,2017,877,628,1109,154,1366,937,976,1002,2075,517,1247,568,2076,271,1227,60,1142,612,1798,223,32,1358,911,683,57,858,100,1625,641,192,1395,484,296,184,1835,466,444,210,906,1030,1511,1582,236,408,1961
|
-0.4645019164518892,0.007304838930220447,0.6704493774995706,0.8994397317643743,0.790742766695202,1.313525421117376,0.8028002615442877,0.7185046953012093,1.6335675616671503,-0.45316226325665193,1.9313637270743245,-0.5436149050829462,-0.3506990843889215,0.24194121516574604,0.37207734287605315,0.12429235183705688,0.24194121516574604,0.19480462663768106,-0.3278331884567082,1.1058224313459646,-1.2467155764480096,0.17127457578516733,0.46717420952267524,-0.039296373688206876,1.448587878163448,-0.2934709455022115,0.11256322969843775,0.07741589559046182,0.05401808025151258,-1.4498904407683808,0.6224784502181606,-0.1783998241784456,0.550683575669592,-1.4498904407683808,1.1058224313459646,-0.15529101731407544,2.081063282881826,-0.06255412202545008,0.4910059425085586,-0.8332862872584502,1.21562356866839,2.470108172021455,-0.28200020167844175,0.13602808391798482,0.4076950458102495,2.118568547897983,0.19480462663768106,1.7697855538291083,-0.5886072916220967,0.45526687448786185,1.3380441413792745,-0.3163874990887109,0.6704493774995706,1.032826380766771,1.3625799253617583,-0.877312180312353,0.7064830339147586,0.7305315408053763,1.2645396465162522,0.14777038932724065,0.030647621232357772,-0.4418133907593946,-0.5323419537246571,1.1911919761542025,0.8148627904870955,-1.0847421306891891
| 2,198
|
Regulation of cytokinesis
| 6
| 14
| 2.809787
| 0.004957
|
Q99570,P0DP25,Q7Z7K6,Q9UN37,Q13618,O95235
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,166,173,341,214,215
|
1167,354,215,166,805,1710,214,1214,173,2,947,341,778,895
|
-0.09738617877579574,0.8994397317643743,1.2278460000913216,1.4117022199123055,0.25374110041581005,-0.7003849198041279,1.2400728339346772,-0.14372513071509743,1.3994153412934467,3.603697827804387,0.11256322969843775,0.9357604892314281,0.28917800305856733,0.15951923187440023
| 2,198
|
Vitamin metabolic process
| 8
| 18
| 2.7778
| 0.005473
|
P04062,Q9H2D1,P50747,Q8N0U8,P00374,P33527,P34896,Q96EY8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
69,7,304,114,216,317,29,160
|
216,69,451,1157,1268,317,29,1224,364,304,1133,114,160,1336,7,1638,661,1972
|
1.2278460000913216,1.9313637270743245,0.7185046953012093,-0.08578282902308276,-0.201477670725542,0.9963911552726393,2.495318194906707,-0.15529101731407544,0.8873425337211313,1.0206766125263118,-0.0509288556690046,1.6582994692435111,1.4362885023075656,-0.2590340742428738,3.167919783326875,-0.5998300912653943,0.431469402737825,-1.095586930046499
| 2,198
|
Cholesterol biosynthesis
| 7
| 15
| 2.64566
| 0.008153
|
P37268,Q15392,Q14534,Q15738,Q14739,O76062,Q9BWD1
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
232,171,109,88,57,93,62
|
93,827,232,1352,1239,1413,1931,109,57,2110,171,88,233,62,493
|
1.7946024492801154,0.23014759192265868,1.1911919761542025,-0.28200020167844175,-0.1668492652198023,-0.3392704044038925,-1.0304132916334157,1.7078101921663897,2.118568547897983,-1.6721507133569484,1.3994153412934467,1.8194344922439065,1.1911919761542025,2.0685685985138393,0.6584486766367807
| 2,198
|
Subsets and Splits
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