term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5
values | subtype stringclasses 24
values | subtype_key stringclasses 24
values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transporter | 61 | 162 | 3.508959 | 0.00045 | Q8NFH4,Q9P2W9,Q15334,P24390,Q9H270,Q9UBX3,P54105,P05023,Q99808,Q15363,Q9H2D1,O96008,Q9BQE5,P23634,P16615,P17900,Q9Y6C9,Q9HD45,Q6NT16,Q9Y619,P35606,P61923,P08183,Q7L0J3,Q70HW3,P38606,Q8IXU6,O43493,Q99805,P12235,Q00765,O43808,Q96S59,Q9Y487,O43760,Q93050,Q92572,O43772,Q9Y3B3,Q9H0U3,Q15070,Q99567,Q9Y678,P04920,Q8N1F7,Q86Y8... | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 128,129,513,3,257,134,255,509,387,384,10,267,18,396,394,395,554,154,27,292,411,544,286,38,40,542,43,169,182,558,307,556,450,62,320,68,585,77,206,335,210,605,609,209,470,469,356,489,227,483,234,499,238,515,111,116,118,490,370,246,388 | 1833,1439,798,1955,695,1026,1586,490,1978,169,1900,320,77,556,926,718,780,1476,828,953,855,2115,1228,761,2179,875,267,209,509,1707,1590,1328,286,1801,2207,1445,1669,558,931,394,395,934,1446,2290,396,3,670,2441,860,2183,835,411,936,1482,499,542,1417,960,111,684,1375,1271,1128,370,1842,1272,1097,1378,596,1039,255,2047,22... | -0.5237411060737124,-0.24785041714148484,0.21130916709284053,-0.6287910407099505,0.3186451392955738,0.033646699417906,-0.34606944879987256,0.565601265268559,-0.6554750699704857,1.38130620151236,-0.5759332603866829,0.8738956173150244,2.1907384712256417,0.4848802844441598,0.10115585811536389,0.29739620791205207,0.2329969... | 2,468 |
Exopeptidase activity | 10 | 27 | 3.480561 | 0.0005 | O14773,Q9H3G5,Q9HB40,P09960,P55786,P42785,Q9UIQ6,P50579,P10619,Q969V3 | Functions | GO Molecular function | msigdb_gomf | 94,65,34,103,110,17,19,52,61,30 | 94,185,829,591,103,61,2208,2368,1909,1483,17,52,110,939,965,790,514,376,30,817,65,850,34,2256,1614,1505,19 | 1.9374688026168079,1.3148080906459898,0.18950873816397323,0.4439327299123976,1.8643955467119475,2.3910310244631345,-0.9037132041831669,-1.322298943353699,-0.5759332603866829,-0.27218882129392213,3.5827914390839197,2.5824892901533407,1.7900609938314576,0.10115585811536389,0.07877351189206046,0.2329969417200938,0.5455653... | 2,468 |
Lipid metabolic process | 48 | 207 | 3.470004 | 0.00052 | Q8N4Q0,Q9H6V9,Q5H8A4,Q9BT22,O95470,Q9BQE5,P11802,P16278,P07602,Q16134,P40939,Q9HB40,Q8WTV0,P50897,Q9NPH2,Q9BZF1,Q15392,P11310,P04062,Q9UBM7,Q99805,O75844,P06280,Q14739,P04066,Q9NZ01,P07099,Q16739,Q96G23,Q9P035,O15121,O14773,Q06136,O15269,O76062,P09960,O75874,Q9UBF8,P06865,Q6NUM9,Q13510,Q15800,Q86UY6,Q9NPH0,P35790,Q1685... | Processes and pathways | GO Biological process | msigdb_gobp | 1,8,139,140,143,18,153,25,28,31,33,34,36,39,168,172,47,175,49,51,182,185,187,63,189,70,199,72,78,214,86,94,97,223,102,103,104,106,232,239,112,114,117,251,119,121,245,123 | 521,2113,123,2448,2453,1052,2320,94,381,696,86,223,1475,556,925,244,1956,2386,2114,1226,698,185,104,102,2345,143,1544,245,1798,49,189,1292,509,2449,2070,187,1328,232,199,28,1546,103,175,2458,2429,1627,153,2209,280,496,2181,1928,2433,25,326,395,651,805,2182,1838,293,2298,2441,2094,860,1370,1333,2212,580,1293,994,995,119... | 0.5254338786156286,-0.7915396678024824,1.6837858907333896,-2.4782507088829866,-2.6900423224636016,0.0108995245257502,-1.137659851909859,1.9374688026168079,0.7225559645801342,0.3186451392955738,2.023552801349019,1.1264079353050018,-0.27218882129392213,0.4848802844441598,0.10115585811536389,1.0557791765577014,-0.62879104... | 2,468 |
Sphingolipid metabolism | 12 | 23 | 3.439177 | 0.000583 | Q06136,O15269,Q16739,Q96G23,Q13510,O95470,P04062,O15121,P16278,P06280,P07602,P10619 | Processes and pathways | Reactome Pathways | msigdb_reactome | 97,223,72,78,112,143,49,86,25,187,28,61 | 86,223,1475,2179,143,49,187,232,28,1546,61,25,395,805,441,97,112,72,78,1997,1726,388,1438 | 2.023552801349019,1.1264079353050018,-0.27218882129392213,-0.8753826232126409,1.5431638652413855,2.644481441197411,1.2980205320115141,1.1088603313127976,3.198719452250958,-0.32129657210781537,2.3910310244631345,3.273996348775714,0.7032523978558017,0.21130916709284053,0.6448072914475071,1.9229529370253255,1.775038738472... | 2,468 |
SLC superfamily of solute carriers | 13 | 41 | 3.326398 | 0.00088 | Q9UBX3,Q7L0J3,Q9HC07,Q70HW3,Q9H2D1,Q8IXU6,O43772,Q9H0U3,Q8TB61,P04920,Q6NT16,Q9Y619,Q9NZJ7 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 134,38,234,40,10,43,77,335,118,209,27,292,388 | 77,556,855,761,875,209,1590,1801,1445,558,931,1842,596,810,1163,962,1136,910,27,1526,1347,40,38,43,118,387,1996,888,335,10,1724,1580,665,234,515,388,134,920,1179,292,554 | 2.1907384712256417,0.4848802844441598,0.16759443900767257,0.2545732583950417,0.14556503368975818,1.1786210307382605,-0.34606944879987256,-0.49788927155059765,-0.24785041714148484,0.4848802844441598,0.10115585811536389,-0.5237411060737124,0.4439327299123976,0.21130916709284053,-0.058093817935866696,0.07877351189206046,-... | 2,468 |
Transmembrane transport | 39 | 175 | 3.305006 | 0.00095 | Q99595,Q9UBX3,P21796,Q9H2D1,P45880,P62942,O96008,O14925,Q9C0H2,Q9UDW1,Q6NT16,Q9Y619,P08183,Q8WTV0,Q7L0J3,Q70HW3,Q8IXU6,Q9UHG3,Q9BZF1,P39210,P23786,P04062,O75964,Q9Y277,Q9NS69,O75844,Q8N668,Q00535,O43772,Q15629,Q9H0U3,Q9HD20,P04920,Q13423,Q8N4V1,Q9HC07,Q8TB61,Q03519,P78417 | Processes and pathways | GO Biological process | msigdb_gobp | 4,134,6,10,14,271,267,266,20,151,27,292,286,36,38,40,43,44,172,302,293,49,50,178,57,185,314,328,77,79,335,81,209,344,352,234,118,246,127 | 1181,1439,1700,1834,266,854,522,77,556,873,1587,480,828,2005,2373,2352,1506,1730,855,185,1731,2115,50,1507,761,875,700,267,2322,49,209,509,1707,1590,1800,1328,2206,1763,2180,286,1801,2091,432,701,1509,2399,1445,2458,558,931,857,394,1411,934,2093,1446,2290,1480,6,396,293,670,2441,703,1806,860,2347,2120,763,994,835,936,2... | -0.08134699713241711,-0.24785041714148484,-0.4212859664531922,-0.5237411060737124,1.002027140929854,0.16759443900767257,0.5254338786156286,2.1907384712256417,0.4848802844441598,0.14556503368975818,-0.34606944879987256,0.5855424906777212,0.18950873816397323,-0.6823322307636482,-1.3538973144414643,-1.228940433793697,-0.2... | 2,468 |
transporter | 23 | 52 | 3.253249 | 0.001141 | Q99808,Q8NFH4,P54105,Q99595,Q9H2D1,Q9HD45,Q9Y619,P39210,Q99805,O75694,O00410,Q96P70,O43772,Q15070,Q9HAV4,Q8N1F7,Q567V2,Q8TEX9,O15397,P37198,Q14974,Q92973,P52294 | Functions | Panther Protein class | panther_protein_class | 387,128,255,4,10,154,292,302,182,180,319,463,77,210,347,470,96,227,479,499,238,116,370 | 319,1955,695,1586,1403,479,854,1475,77,718,180,650,1192,499,302,960,1712,1128,370,1096,1842,596,255,1040,1273,2348,1458,238,210,96,910,2235,470,128,1104,227,814,116,2134,463,605,4,182,387,2306,10,347,154,757,1999,519,292 | 0.8738956173150244,-0.6287910407099505,0.3186451392955738,-0.34606944879987256,-0.22365336069552152,0.5855424906777212,0.16759443900767257,-0.27218882129392213,2.1907384712256417,0.29739620791205207,1.3315299103873544,0.3817551739233301,-0.08134699713241711,0.565601265268559,0.9292833665100879,0.07877351189206046,-0.42... | 2,468 |
Inorganic anion transport | 8 | 22 | 3.178322 | 0.001481 | P54105,Q9UBX3,P21796,Q9UHG3,P45880,Q9Y277,Q9C0H2,P04920 | Processes and pathways | GO Biological process | msigdb_gobp | 255,134,6,44,14,178,20,209 | 1700,1475,209,286,432,6,1293,835,14,2409,255,810,1163,962,1388,910,20,1016,134,44,178,1179 | -0.4212859664531922,-0.27218882129392213,1.1786210307382605,0.9658109974394301,0.6448072914475071,4.254918317045912,-0.15189356987392963,0.18950873816397323,3.796269049554577,-1.615882187826786,1.0379372362963877,0.21130916709284053,-0.058093817935866696,0.07877351189206046,-0.1995959661077008,0.12341926582388701,3.420... | 2,468 |
Protein transport | 88 | 195 | 3.172154 | 0.001513 | P24390,Q99595,A6NIH7,Q92621,O43707,P61923,Q9NS69,Q9NVZ3,Q9H269,Q92572,Q15629,Q9HD20,Q9BTX1,Q99567,Q8WUM4,Q9Y678,Q9UL25,Q96ED9,P49257,Q92973,Q12893,O15126,Q9P2W9,Q8NFH4,Q3ZCQ8,Q15437,O43264,Q8TD16,O95373,Q8N4H5,P49755,P20339,O75694,Q9UGP8,Q99747,Q9H267,Q15907,O15127,O00629,Q9Y3B3,Q15388,O60684,P51153,Q15436,P41208,P4932... | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 3,4,11,531,522,544,57,590,587,585,79,81,83,605,603,609,627,622,111,116,618,631,129,128,636,133,632,661,650,177,684,680,180,715,713,714,707,194,695,206,731,718,726,218,724,725,227,717,222,757,238,246,257,264,274,267,266,312,306,314,319,336,330,347,356,354,350,364,370,384,407,403,411,420,436,432,463,471,470,469,466,465,4... | 222,11,1584,1833,1439,798,319,1955,695,1026,1586,490,465,266,330,1403,466,631,194,479,1703,632,854,717,522,2037,1900,2068,718,780,1476,2140,480,896,1406,1506,1925,2007,953,180,2205,2038,1228,1188,650,1979,267,432,1410,436,1630,680,1364,3,411,1192,1964,499,724,1676,1417,111,725,684,1712,1198,1713,2123,726,1375,1271,1128... | 1.1264079353050018,3.926954124542245,-0.34606944879987256,-0.5237411060737124,-0.24785041714148484,0.21130916709284053,0.8738956173150244,-0.6287910407099505,0.3186451392955738,0.033646699417906,-0.34606944879987256,0.565601265268559,0.6053899682620425,1.002027140929854,0.8365644866172669,-0.22365336069552152,0.6053899... | 2,468 |
Intrinsic component of endoplasmic reticulum membrane | 19 | 45 | 3.16295 | 0.001562 | Q5H8A4,Q9BUN8,Q9Y282,O95470,Q9NQC3,P10321,P57088,Q9HCU5,Q9UBM7,Q86XL3,O75844,Q9NZ01,Q15629,Q9P035,Q8N4V1,O76062,Q9Y4P3,Q8TB61,Q03519 | Localization | GO Cellular component | msigdb_gocc | 139,274,13,143,149,418,303,312,51,54,185,70,79,214,352,102,380,118,246 | 1052,185,102,143,900,418,2161,1710,2327,1375,303,2348,246,674,1646,2381,881,79,139,1390,1529,54,352,1608,118,1495,449,1312,816,1892,916,1997,274,756,312,1538,149,70,214,1287,51,1081,13,380,1793 | 0.0108995245257502,1.3148080906459898,1.8643955467119475,1.5431638652413855,0.12341926582388701,0.6643789100172187,-0.8472453003312823,-0.4212859664531922,-1.137659851909859,-0.1995959661077008,0.9292833665100879,-1.1982874368625742,1.0557791765577014,0.3608235263603773,-0.3709907348752914,-1.4178355631317874,0.1455650... | 2,468 |
Membrane lipid biosynthetic process | 10 | 20 | 3.154507 | 0.001608 | Q06136,Q16739,Q5H8A4,Q96G23,Q13510,O95470,P04062,Q99805,Q9P035,O15121 | Processes and pathways | GO Biological process | msigdb_gobp | 97,72,139,78,112,143,49,182,214,86 | 86,223,143,49,805,97,112,72,1389,139,2315,449,1312,78,1892,182,756,1726,214,1438 | 2.023552801349019,1.1264079353050018,1.5431638652413855,2.644481441197411,0.21130916709284053,1.9229529370253255,1.7750387384721054,2.312020878410862,-0.1995959661077008,1.5748140446524133,-1.1076784324720763,0.6448072914475071,-0.15189356987392963,2.1633192386683975,-0.5497550639890549,1.3315299103873544,0.27603929431... | 2,468 |
Endoplasmic reticulum golgi intermediate compartment | 18 | 41 | 3.151703 | 0.001623 | Q15363,Q02818,P24390,O15258,Q08379,Q14789,Q9Y282,Q9Y3B3,P49257,Q8N511,Q96GC9,P09429,Q03519,P80303,Q92538,Q10472,Q9Y3Q3,Q15904 | Localization | GO Cellular component | msigdb_gocc | 384,130,3,166,483,233,13,206,111,16,473,357,246,23,471,468,356,290 | 490,166,1703,1925,1545,357,3,2161,1155,111,684,1771,1375,1272,1056,23,130,246,483,468,1133,730,233,1913,384,290,1606,16,471,1653,473,2340,973,1319,1863,1113,13,1223,206,356,609 | 0.565601265268559,1.3977702991328884,-0.4212859664531922,-0.6022778524744863,-0.32129657210781537,0.7609008970028596,4.4061529638753205,-0.8472453003312823,-0.058093817935866696,1.7750387384721054,0.33978721059520445,-0.4721974863524341,-0.1995959661077008,-0.1282453451374523,0.0108995245257502,3.326987798371381,1.6374... | 2,468 |
Endopeptidase activity | 25 | 50 | 3.141758 | 0.001679 | Q9BYT8,P28072,P07858,P49721,P28074,Q4J6C6,Q93008,Q92643,P42892,O43847,P52888,P20618,O75844,Q5JRX3,Q16740,Q9UPU5,P28070,Q86UV5,Q92542,Q93009,P14735,O14773,P42575,P60900,P49720 | Functions | GO Molecular function | msigdb_gomf | 275,268,24,26,42,421,570,449,56,557,58,559,185,196,67,198,457,338,339,472,467,94,236,501,500 | 94,557,1730,185,1763,24,956,467,559,1233,1929,457,268,42,1909,2327,1675,2263,236,56,996,1515,500,26,58,1420,501,1425,1063,965,1002,67,421,196,2132,338,1495,339,449,604,570,472,2058,793,817,275,1216,1505,198,2067 | 1.9374688026168079,0.4848802844441598,-0.44666371637530605,1.3148080906459898,-0.4721974863524341,3.316440414035143,0.07877351189206046,0.6053899682620425,0.4848802844441598,-0.10473033469147558,-0.6022778524744863,0.6251446041977697,1.002027140929854,2.741870933531249,-0.5759332603866829,-1.137659851909859,-0.39606227... | 2,468 |
Azurophil granule | 19 | 56 | 3.136123 | 0.001712 | P42785,P17900,P16278,P07602,Q07065,Q99536,P06280,Q8NF37,P10619,P04066,P15586,Q9H0U3,Q92542,O00584,Q9BTY2,O00754,P06865,Q92820,Q9NZJ7 | Localization | GO Cellular component | msigdb_gocc | 17,395,25,28,295,311,187,315,61,189,207,335,339,342,100,231,232,376,388 | 1833,342,231,1978,1475,760,896,1798,189,187,232,2206,1265,28,1546,494,61,930,1669,207,25,395,703,498,1333,1633,17,1811,1038,742,1713,1271,1129,1056,2074,615,1241,743,1559,295,1744,1566,2171,1889,315,339,376,425,1281,311,817,100,335,388,1438,921 | -0.5237411060737124,0.7989016296808182,1.1088603313127976,-0.6554750699704857,-0.27218882129392213,0.2545732583950417,0.12341926582388701,-0.49788927155059765,1.281166698194264,1.2980205320115141,1.1088603313127976,-0.9037132041831669,-0.1282453451374523,3.198719452250958,-0.32129657210781537,0.565601265268559,2.391031... | 2,468 |
Ion transmembrane transporter activity | 23 | 90 | 3.129387 | 0.001752 | Q99808,Q9UBX3,P21796,Q9H2D1,P45880,P23634,Q9C0H2,Q9UDW1,Q9Y619,Q70HW3,O75964,Q9Y277,Q9Y487,Q93050,Q00535,O43772,Q9H0U3,Q9HD20,P04920,Q13423,Q8N4V1,Q9HC07,Q8TB61 | Functions | GO Molecular function | msigdb_gomf | 387,134,6,10,14,396,20,151,292,40,50,178,62,68,328,77,335,81,209,344,352,234,118 | 1700,1475,77,556,855,2115,50,761,875,2322,209,509,1707,1590,1328,2206,2180,1801,2091,432,1509,1445,558,931,857,394,934,2093,1446,2290,6,396,670,2441,763,835,936,1482,542,14,2424,2409,1842,596,810,1742,1058,2348,1881,1163,328,962,344,1003,1687,1136,1388,910,1526,1347,1008,40,352,1391,118,1044,68,1654,387,1996,1015,888,2... | -0.4212859664531922,-0.27218882129392213,2.1907384712256417,0.4848802844441598,0.16759443900767257,-0.7915396678024824,2.6073921114062215,0.2545732583950417,0.14556503368975818,-1.137659851909859,1.1786210307382605,0.5455653723813071,-0.4212859664531922,-0.34606944879987256,-0.17567657782693433,-0.9037132041831669,-0.8... | 2,468 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 10 | 25 | 3.104734 | 0.001905 | Q16850,Q8NB78,Q14534,Q15800,P30519,O15121,Q9BU89,O75151,O95864,Q9H6W3 | Functions | GO Molecular function | msigdb_gomf | 121,7,296,114,21,86,120,217,245,124 | 1184,1052,86,2227,217,245,1545,1668,1091,326,1370,21,1879,1560,1815,296,114,121,1069,638,412,7,120,124,1728 | -0.08134699713241711,0.0108995245257502,2.023552801349019,-0.9322398063664452,1.1438835156965523,1.0557791765577014,-0.32129657210781537,-0.3960622793653552,-0.011972007198974987,0.8552711400416021,-0.1995959661077008,3.368926559380632,-0.5497550639890549,-0.32129657210781537,-0.49788927155059765,0.9475864635773026,1.7... | 2,468 |
Sphingolipid biosynthetic process | 9 | 14 | 3.036183 | 0.002396 | Q06136,Q16739,Q96G23,Q13510,P04062,O95470,Q99805,Q9P035,O15121 | Processes and pathways | GO Biological process | msigdb_gobp | 97,72,78,112,49,143,182,214,86 | 86,223,143,49,805,97,112,72,1389,78,182,1726,214,1438 | 2.023552801349019,1.1264079353050018,1.5431638652413855,2.644481441197411,0.21130916709284053,1.9229529370253255,1.7750387384721054,2.312020878410862,-0.1995959661077008,2.1633192386683975,1.3315299103873544,-0.4212859664531922,1.1786210307382605,-0.22365336069552152 | 2,468 |
Protein kinase complex | 10 | 22 | 2.983997 | 0.002845 | P12956,Q00534,P54646,P14635,Q00535,P24941,P78527,P10644,P11802,Q96T76 | Localization | GO Cellular component | msigdb_gocc | 321,322,383,434,328,224,482,495,153,317 | 1030,495,153,987,321,1190,1092,434,933,1671,224,937,1098,383,482,322,328,317,979,950,1321,520 | 0.033646699417906,0.565601265268559,1.4952459017765753,0.05627090662211817,0.8738956173150244,-0.08134699713241711,-0.011972007198974987,0.6448072914475071,0.10115585811536389,-0.3960622793653552,1.1264079353050018,0.10115585811536389,-0.011972007198974987,0.7225559645801342,0.5855424906777212,0.8738956173150244,0.8552... | 2,468 |
Proteolysis | 106 | 306 | 2.980149 | 0.002881 | Q8IYS1,Q15005,P51665,Q6ZXV5,Q9UNN5,O75150,Q9UJX2,P42785,Q9UIQ6,P07858,P49721,P63208,Q9NR28,Q969V3,Q8IXB1,O75503,Q9HB40,P28074,Q9UHG3,P19474,Q93008,Q15392,P04062,Q9H4L4,P50579,O14737,O43847,P42892,P52888,P20618,P10619,Q9H3G5,Q16740,O43242,Q92905,Q8WUM4,Q9UBU6,P49327,P48729,P02786,Q14258,O14773,Q96F07,P09960,Q9ULT8,Q9UNS... | Processes and pathways | GO Biological process | msigdb_gobp | 514,512,511,528,534,12,533,17,19,24,26,545,549,30,547,32,34,42,44,46,570,47,49,571,52,555,557,56,58,559,61,65,67,575,604,603,90,594,593,591,598,94,623,103,628,629,109,110,616,617,648,644,150,174,185,188,190,196,198,220,228,224,236,253,264,265,261,275,274,269,268,284,314,328,326,333,338,339,363,366,362,357,376,372,388,4... | 109,174,284,825,1794,1440,555,94,1796,1403,799,826,575,717,924,557,1618,2140,12,1956,1406,1730,2114,32,985,699,185,1731,829,2204,1958,856,700,1902,591,49,782,1903,1799,1030,2310,1329,2206,1763,24,1189,357,1591,1547,103,1906,61,2399,2208,956,1266,467,326,1411,1736,46,804,559,2362,858,1154,1233,1367,224,1332,1447,1511,19... | 1.7900609938314576,1.3481865209735655,0.9658109974394301,0.18950873816397323,-0.49788927155059765,-0.24785041714148484,0.4848802844441598,1.9374688026168079,-0.49788927155059765,-0.22365336069552152,0.21130916709284053,0.18950873816397323,0.4644562459753665,0.29739620791205207,0.10115585811536389,0.4848802844441598,-0.... | 2,468 |
Predicted secreted proteins | 19 | 40 | 2.974753 | 0.002932 | Q02818,Q9BRX8,P84157,O94919,O75718,P80303,P14174,P07858,P43490,Q8WUJ1,Q9HB40,P78310,Q08380,P26583,O60888,O00584,Q9BTY2,P09429,Q9Y4P3 | Functions | Protein Atlas Protein class | protein_atlas_protein_class | 130,132,272,278,392,23,280,24,29,161,34,294,308,438,74,342,100,357,380 | 342,74,392,1868,278,591,1292,1329,2206,24,357,1625,280,467,2358,438,29,1741,1097,1158,294,23,272,130,1683,308,1775,1603,619,2384,161,1653,132,100,850,2028,34,1505,822,380 | 0.7989016296808182,2.258536285683305,0.7032523978558017,-0.5497550639890549,0.9839576617525956,0.4439327299123976,-0.15189356987392963,-0.17567657782693433,-0.9037132041831669,3.316440414035143,0.7609008970028596,-0.3709907348752914,0.9839576617525956,0.6053899682620425,-1.2598242554926813,0.6448072914475071,3.17697288... | 2,468 |
Generalized onset seizure | 20 | 85 | 2.95824 | 0.003094 | Q9UBB4,Q01105,P00374,P16278,O00429,P07602,Q9Y619,O75503,P49591,Q96F86,P04062,Q96N66,P40763,Q9NZ01,P27635,Q14108,Q9Y3E5,Q9Y263,Q96C86,Q13510 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 258,145,279,25,152,28,292,32,287,299,49,316,188,70,85,87,368,366,361,112 | 152,490,827,576,925,1618,430,32,1228,898,1706,279,49,782,509,28,1445,1764,25,933,1982,1671,720,957,85,498,1984,1448,1294,188,1037,765,1055,287,2124,1877,2416,1376,1199,1843,810,766,788,1132,145,2218,1384,744,864,1775,112,87,1566,1489,748,1429,884,1392,570,1312,361,2286,299,2191,316,1612,2269,1213,1075,1580,1047,464,208... | 1.4952459017765753,0.565601265268559,0.18950873816397323,0.4644562459753665,0.10115585811536389,-0.3709907348752914,0.6448072914475071,3.010346969899404,-0.10473033469147558,0.12341926582388701,-0.4212859664531922,0.9839576617525956,2.644481441197411,0.2329969417200938,0.5455653723813071,3.198719452250958,-0.2478504171... | 2,468 |
Sphingolipid metabolism in senescence | 9 | 12 | 2.953942 | 0.003137 | Q06136,O15269,Q16739,Q96G23,Q13510,P04062,O15121,P11802,P16278 | Processes and pathways | WikiPathways | msigdb_wp | 97,223,72,78,112,49,86,153,25 | 86,223,49,153,25,224,498,1037,97,112,72,78 | 2.023552801349019,1.1264079353050018,2.644481441197411,1.4952459017765753,3.273996348775714,1.1264079353050018,0.565601265268559,0.033646699417906,1.9229529370253255,1.7750387384721054,2.312020878410862,2.1633192386683975 | 2,468 |
Serine hydrolase activity | 6 | 16 | 2.943687 | 0.003243 | O14773,Q9H3G5,Q9HB40,Q16740,P42785,P10619 | Functions | GO Molecular function | msigdb_gomf | 94,65,34,67,17,61 | 94,829,61,956,1909,1675,17,1515,1096,1425,67,421,196,1216,65,34 | 1.9374688026168079,0.18950873816397323,2.3910310244631345,0.07877351189206046,-0.5759332603866829,-0.3960622793653552,3.5827914390839197,-0.29667029004619083,-0.011972007198974987,-0.22365336069552152,2.338517782432342,0.6643789100172187,1.2472580264373727,-0.08134699713241711,2.351705786875822,2.9533677053572944 | 2,468 |
Endoplasmic reticulum golgi intermediate compartment membrane | 12 | 23 | 2.940652 | 0.003275 | Q15363,P24390,Q08379,Q9Y282,Q9Y3B3,P49257,Q8N511,Q96GC9,Q03519,Q10472,Q9Y3Q3,Q15904 | Localization | GO Cellular component | msigdb_gocc | 384,3,483,13,206,111,16,473,246,468,356,290 | 490,1703,1925,3,2161,111,684,1375,246,483,468,1133,730,384,290,16,473,973,1319,13,1223,206,356 | 0.565601265268559,-0.4212859664531922,-0.6022778524744863,4.4061529638753205,-0.8472453003312823,1.7750387384721054,0.33978721059520445,-0.1995959661077008,1.0557791765577014,0.5855424906777212,0.6053899682620425,-0.03496930883195915,0.29739620791205207,0.7225559645801342,0.9658109974394301,3.661615789484984,0.60538996... | 2,468 |
Lytic vacuole organization | 7 | 21 | 2.939869 | 0.003284 | O75503,O14773,P50897,P11117,Q8N511,P04062,Q14108 | Processes and pathways | GO Biological process | msigdb_gobp | 32,94,39,167,16,49,87 | 798,94,32,985,49,1546,494,167,1037,39,2123,1200,1641,87,2171,16,1012,622,2057,234,1864 | 0.21130916709284053,1.9374688026168079,3.010346969899404,0.05627090662211817,2.644481441197411,-0.32129657210781537,0.565601265268559,1.3977702991328884,0.033646699417906,2.8135128951122743,-0.7915396678024824,-0.08134699713241711,-0.3709907348752914,2.0093242006690732,-0.8472453003312823,3.661615789484984,0.0562709066... | 2,468 |
Chemical homeostasis | 33 | 146 | 2.931995 | 0.003368 | Q99808,P54646,P49366,Q15067,Q96CP7,Q8N511,P42785,P62942,P23634,P30519,Q9NQC3,Q9HCD5,Q15904,O75503,Q8WTV0,Q7L0J3,P50897,P04062,P40763,Q8NF37,Q9Y487,Q8N668,Q93050,Q00535,Q16739,Q9HD20,Q9P035,P04920,Q9HC07,Q96EB6,Q5BJF2,P09429,P78417 | Processes and pathways | GO Biological process | msigdb_gobp | 387,383,138,400,15,16,17,271,396,21,149,158,290,32,36,38,39,49,188,315,62,314,68,328,72,81,214,209,234,362,240,357,127 | 1439,798,1440,1586,696,1326,1120,1587,2140,828,32,985,1360,1901,1666,761,2179,875,899,591,49,1407,209,509,1707,1328,783,1329,1546,2180,1362,357,1668,1547,432,701,955,702,1266,1928,394,435,1907,1479,1411,1629,934,1765,805,396,1123,1806,2161,1983,498,1909,21,1293,2120,995,936,542,188,1711,17,2419,138,39,2123,1419,1375,58... | -0.24785041714148484,0.21130916709284053,-0.24785041714148484,-0.34606944879987256,0.3186451392955738,-0.17567657782693433,-0.03496930883195915,-0.34606944879987256,-0.8192985310386937,0.18950873816397323,3.010346969899404,0.05627090662211817,-0.1995959661077008,-0.5759332603866829,-0.3960622793653552,0.254573258395041... | 2,468 |
Abnormal circulating lipid concentration | 17 | 60 | 2.923581 | 0.00346 | P40939,Q16836,P23786,O43772,P11310,Q8N511,O95470,Q15392,Q9UBM7,P49257,Q9Y4P3,Q15800,O75844,P06280,P07602,Q14739,Q15904 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 33,351,293,77,175,16,143,47,51,111,380,114,185,187,28,63,290 | 853,522,77,1506,2007,185,1360,143,2142,187,783,28,1591,175,1122,293,457,1983,1295,541,1296,592,33,1452,111,1965,809,837,878,1843,2167,1273,1773,1275,2349,1882,907,1460,63,1776,47,2437,114,290,351,2363,16,1853,1010,1312,868,1613,796,388,51,1660,920,922,1760,380 | 0.16759443900767257,0.5254338786156286,2.1907384712256417,-0.29667029004619083,-0.6823322307636482,1.3148080906459898,-0.1995959661077008,1.5431638652413855,-0.8192985310386937,1.2980205320115141,0.2329969417200938,3.198719452250958,-0.34606944879987256,1.3481865209735655,-0.03496930883195915,0.9475864635773026,0.62514... | 2,468 |
Lipid localization | 22 | 57 | 2.911462 | 0.003597 | Q9H6V9,Q9BXB4,P17900,Q9BQE5,P14174,P07602,P08183,Q8WTV0,Q14534,Q9BZF1,P23786,P04062,Q16739,O43772,Q99720,Q96GC9,Q14108,Q86Y82,Q96EB6,P35790,Q9UJZ1,Q9NZJ7 | Processes and pathways | GO Biological process | msigdb_gobp | 8,532,395,18,280,28,286,36,296,172,293,49,72,77,80,473,87,469,362,119,519,388 | 2453,696,77,556,926,1406,1544,2323,49,1292,2206,28,1546,832,286,1445,280,395,805,2182,293,860,1370,1293,994,835,995,119,960,1339,525,87,296,72,1388,2171,1347,469,2384,36,362,473,1108,80,18,1997,532,172,819,8,388,1438,775,2088,519,759,1793 | -2.6900423224636016,0.3186451392955738,2.1907384712256417,0.4848802844441598,0.10115585811536389,-0.22365336069552152,-0.32129657210781537,-1.137659851909859,2.644481441197411,-0.15189356987392963,-0.9037132041831669,3.198719452250958,-0.32129657210781537,0.18950873816397323,0.9658109974394301,-0.24785041714148484,0.98... | 2,468 |
Regulation of cellular ph | 7 | 20 | 2.911225 | 0.0036 | O75503,Q93050,P50897,Q9HC07,Q8N511,P04920,Q9Y487 | Processes and pathways | GO Biological process | msigdb_gobp | 32,68,39,234,16,209,62 | 32,985,209,1328,432,1123,498,39,2123,1058,2218,290,16,814,68,1012,234,1113,738,62 | 3.010346969899404,0.05627090662211817,1.1786210307382605,-0.17567657782693433,0.6448072914475071,-0.03496930883195915,0.565601265268559,2.8135128951122743,-0.7915396678024824,0.0108995245257502,-0.9037132041831669,0.9658109974394301,3.661615789484984,0.21130916709284053,2.338517782432342,0.05627090662211817,1.108860331... | 2,468 |
Regulation of ph | 7 | 20 | 2.911225 | 0.0036 | O75503,Q93050,P50897,Q9HC07,Q8N511,P04920,Q9Y487 | Processes and pathways | GO Biological process | msigdb_gobp | 32,68,39,234,16,209,62 | 32,985,209,1328,432,1123,498,39,2123,1058,2218,290,16,814,68,1012,234,1113,738,62 | 3.010346969899404,0.05627090662211817,1.1786210307382605,-0.17567657782693433,0.6448072914475071,-0.03496930883195915,0.565601265268559,2.8135128951122743,-0.7915396678024824,0.0108995245257502,-0.9037132041831669,0.9658109974394301,3.661615789484984,0.21130916709284053,2.338517782432342,0.05627090662211817,1.108860331... | 2,468 |
Ceramide metabolic process | 9 | 16 | 2.904888 | 0.003674 | O15269,Q16739,Q96G23,Q13510,P04062,O95470,Q99805,O15121,P06280 | Processes and pathways | GO Biological process | msigdb_gobp | 223,72,78,112,49,143,182,86,187 | 86,223,143,49,187,232,1546,395,580,112,72,1389,711,78,182,1726 | 2.023552801349019,1.1264079353050018,1.5431638652413855,2.644481441197411,1.2980205320115141,1.1088603313127976,-0.32129657210781537,0.7032523978558017,0.4644562459753665,1.7750387384721054,2.312020878410862,-0.1995959661077008,0.3186451392955738,2.1633192386683975,1.3315299103873544,-0.4212859664531922 | 2,468 |
Anion transmembrane transport | 9 | 40 | 2.874239 | 0.00405 | Q9UBX3,P21796,Q9H2D1,Q9UHG3,P45880,Q9Y277,Q8TB61,P04920,Q9Y619 | Processes and pathways | GO Biological process | msigdb_gobp | 134,6,10,44,14,178,118,209,292 | 556,480,855,1731,875,209,1590,1800,286,1801,558,931,6,835,14,2409,1842,596,810,1163,962,1003,881,1136,1388,118,1996,888,10,1580,665,515,364,134,44,920,178,1179,1023,292 | 0.4848802844441598,0.5855424906777212,0.16759443900767257,-0.44666371637530605,0.14556503368975818,1.1786210307382605,-0.34606944879987256,-0.49788927155059765,0.9658109974394301,-0.49788927155059765,0.4848802844441598,0.10115585811536389,4.254918317045912,0.18950873816397323,3.796269049554577,-1.615882187826786,-0.523... | 2,468 |
Hydrolase activity acting on glycosyl bonds | 9 | 22 | 2.834943 | 0.004583 | O75503,P04066,Q9BTY2,O00754,P06865,P04062,P16278,P06280,O60502 | Functions | GO Molecular function | msigdb_gomf | 32,189,100,231,232,49,25,187,95 | 231,2226,95,32,49,189,187,232,1546,494,987,25,395,1367,1806,301,541,1200,1716,1524,100,517 | 1.1088603313127976,-0.9322398063664452,1.9374688026168079,3.010346969899404,2.644481441197411,1.281166698194264,1.2980205320115141,1.1088603313127976,-0.32129657210781537,0.565601265268559,0.05627090662211817,3.273996348775714,0.7032523978558017,-0.1995959661077008,-0.49788927155059765,0.9292833665100879,0.505205836547... | 2,468 |
ER-Golgi transport | 14 | 39 | 2.829126 | 0.004668 | Q15363,Q9P2W9,P24390,P18085,Q15437,P62820,Q969M3,O95197,Q9Y282,Q13618,P49257,Q9HCU5,Q15436,P35606 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 384,129,3,436,133,420,403,75,13,372,111,312,218,411 | 1026,466,1703,632,1476,1925,1228,75,436,1364,3,411,1417,111,684,1375,1272,1097,1039,2215,544,420,674,372,384,218,133,2025,813,1253,1693,1010,403,713,312,917,129,13,609 | 0.033646699417906,0.6053899682620425,-0.4212859664531922,0.4025832237568715,-0.27218882129392213,-0.6022778524744863,-0.10473033469147558,2.2315443900172007,0.6448072914475071,-0.1995959661077008,4.4061529638753205,0.6838603272070093,-0.22365336069552152,1.7750387384721054,0.33978721059520445,-0.1995959661077008,-0.128... | 2,468 |
Sphingolipid metabolism | 8 | 11 | 2.824709 | 0.004732 | Q06136,Q16739,Q13510,P04062,O95470,O15121,P16278,P06280 | Processes and pathways | KEGG Pathways | msigdb_kegg | 97,72,112,49,143,86,25,187 | 86,223,1475,143,49,187,25,97,112,72,1726 | 2.023552801349019,1.1264079353050018,-0.27218882129392213,1.5431638652413855,2.644481441197411,1.2980205320115141,3.273996348775714,1.9229529370253255,1.7750387384721054,2.312020878410862,-0.4212859664531922 | 2,468 |
Enzyme activator activity | 25 | 84 | 2.819147 | 0.004815 | O43169,Q15437,P21359,P17900,O00429,O75569,P07602,Q15257,Q9HCU5,Q15042,Q7KZI7,Q9H6U6,P10619,Q5JRX3,Q69YN2,O60343,Q9P035,Q15436,Q9H6Z4,Q9Y263,Q14185,P40616,Q8TC07,Q4KMP7,Q9NZJ7 | Functions | GO Molecular function | msigdb_gomf | 5,133,144,395,152,277,28,297,312,444,446,318,61,196,201,325,214,218,354,366,237,358,250,248,388 | 152,1794,1440,555,5,325,277,2204,831,28,701,61,987,1190,434,395,144,1294,1840,723,1633,358,2263,1553,1450,1416,1198,1811,1635,2074,2251,904,1936,616,879,1061,1275,841,906,1244,1684,237,941,1990,658,1135,444,297,513,218,133,248,196,1690,201,446,1691,1253,250,1434,752,1213,869,1016,948,1353,318,354,312,666,2288,388,214,1... | 1.4952459017765753,-0.49788927155059765,-0.24785041714148484,0.4848802844441598,4.254918317045912,0.8552711400416021,0.9839576617525956,-0.9037132041831669,0.18950873816397323,3.198719452250958,0.3186451392955738,2.3910310244631345,0.05627090662211817,-0.08134699713241711,0.6448072914475071,0.7032523978558017,1.5431638... | 2,468 |
Monovalent inorganic cation homeostasis | 7 | 25 | 2.802913 | 0.005064 | O75503,Q93050,P50897,Q9HC07,Q8N511,P04920,Q9Y487 | Processes and pathways | GO Biological process | msigdb_gobp | 32,68,39,234,16,209,62 | 32,985,1407,209,509,1707,1328,432,1123,498,39,2123,2047,810,1058,2218,290,16,814,68,1012,234,1113,738,62 | 3.010346969899404,0.05627090662211817,-0.22365336069552152,1.1786210307382605,0.5455653723813071,-0.4212859664531922,-0.17567657782693433,0.6448072914475071,-0.03496930883195915,0.565601265268559,2.8135128951122743,-0.7915396678024824,-0.7093648604789845,0.21130916709284053,0.0108995245257502,-0.9037132041831669,0.9658... | 2,468 |
Process utilizing autophagic mechanism | 41 | 122 | 2.798693 | 0.005131 | Q9H270,P54646,Q99816,P21796,Q9UNH7,P16615,Q9Y2S7,O00429,P07602,P55061,P38606,P62820,P19474,P04062,Q15042,Q66K74,P12235,Q7KZI7,O75844,Q9H6U6,P40763,P10619,Q9Y487,Q9H269,Q93050,Q00535,Q9NZ45,O14964,Q96GC9,Q16543,Q86Y82,O15027,Q9UPT5,P50851,O15269,Q9Y6I9,Q08379,Q9Y263,Q96EB6,P09429,Q9NZJ7 | Processes and pathways | GO Biological process | msigdb_gobp | 257,383,264,6,407,394,553,152,28,543,542,420,46,49,444,567,558,446,185,318,188,61,62,587,68,328,71,330,473,211,469,466,489,225,223,369,483,366,362,357,388 | 1977,152,330,466,696,223,1053,717,1406,1925,953,185,1958,1361,49,1903,1799,2246,1590,1763,28,1031,1087,1802,357,1668,61,1960,1331,558,394,1411,46,804,1232,680,1446,2290,6,1123,1806,1293,542,188,1037,2263,2250,704,225,2123,1271,582,1678,383,543,2074,1299,1058,420,1426,1743,328,1132,963,1384,483,1816,634,1002,444,1718,21... | -0.6554750699704857,1.4952459017765753,0.8365644866172669,0.6053899682620425,0.3186451392955738,1.1264079353050018,0.0108995245257502,0.29739620791205207,-0.22365336069552152,-0.6022778524744863,0.07877351189206046,1.3148080906459898,-0.6287910407099505,-0.1995959661077008,2.644481441197411,-0.5759332603866829,-0.49788... | 2,468 |
Cellular monovalent inorganic cation homeostasis | 7 | 24 | 2.793901 | 0.005208 | O75503,Q93050,P50897,Q9HC07,Q8N511,P04920,Q9Y487 | Processes and pathways | GO Biological process | msigdb_gobp | 32,68,39,234,16,209,62 | 32,985,209,509,1707,1328,432,1123,498,39,2123,2047,810,1058,2218,290,16,814,68,1012,234,1113,738,62 | 3.010346969899404,0.05627090662211817,1.1786210307382605,0.5455653723813071,-0.4212859664531922,-0.17567657782693433,0.6448072914475071,-0.03496930883195915,0.565601265268559,2.8135128951122743,-0.7915396678024824,-0.7093648604789845,0.21130916709284053,0.0108995245257502,-0.9037132041831669,0.9658109974394301,3.661615... | 2,468 |
Protein catabolic process | 58 | 210 | 2.767682 | 0.005646 | Q9NUJ1,Q9H270,P51665,Q99816,Q9GZP4,Q6ZXV5,Q9UNN5,O75150,Q16763,Q9BUN8,Q9UJX3,Q8N511,P46379,Q9UIQ6,P28072,P07858,P49721,O75503,O00231,Q9H2J4,P50897,Q96CS3,Q92990,P28074,Q9UHG3,A4D1P6,P04062,Q8N3C0,O75844,Q5VTR2,Q8NF37,P10619,Q8N668,Q16740,Q9UPU5,O14964,P49427,P28070,Q86UV5,Q93009,Q9UBU6,P14735,O60502,Q96J02,O14773,Q9UJX... | Processes and pathways | GO Biological process | msigdb_gobp | 517,257,511,264,265,528,534,12,261,274,406,16,269,19,268,24,26,32,284,427,39,425,423,42,44,174,49,448,185,445,315,61,314,67,198,330,333,457,338,472,90,467,95,228,94,488,224,363,366,507,362,109,501,500,253,121,372,518 | 109,174,284,1794,94,1796,330,1403,1326,799,826,575,717,924,557,2068,95,1618,2140,12,1406,1925,2114,32,698,699,185,2204,1958,856,49,2206,24,1031,1189,1087,1906,61,1960,1266,467,1764,1411,1736,804,559,1480,858,1154,224,1332,1447,1511,1929,1805,2161,1710,1767,457,268,42,1371,1674,2213,2042,2073,1675,1037,2144,996,269,1676... | 1.7900609938314576,1.3481865209735655,0.9658109974394301,-0.49788927155059765,1.9374688026168079,-0.49788927155059765,0.8365644866172669,-0.22365336069552152,-0.17567657782693433,0.21130916709284053,0.18950873816397323,0.4644562459753665,0.29739620791205207,0.10115585811536389,0.4848802844441598,-0.7365753446833382,1.9... | 2,468 |
Abnormality of head blood vessel | 8 | 21 | 2.766576 | 0.005665 | P06865,Q13510,P21359,Q9Y4P3,P16278,P07602,P10619,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 232,112,144,380,25,28,61,388 | 853,1899,232,28,1546,61,1152,25,395,144,651,1295,1039,1773,112,1776,1072,889,388,1660,380 | 0.16759443900767257,-0.5759332603866829,1.1088603313127976,3.198719452250958,-0.32129657210781537,2.3910310244631345,-0.058093817935866696,3.273996348775714,0.7032523978558017,1.5431638652413855,0.3817551739233301,-0.15189356987392963,0.033646699417906,-0.4721974863524341,1.7750387384721054,-0.4721974863524341,0.010899... | 2,468 |
Anion transmembrane transporter activity | 8 | 41 | 2.765199 | 0.005689 | Q9UBX3,P21796,Q9H2D1,P45880,Q9Y277,Q9C0H2,Q8TB61,P04920 | Functions | GO Molecular function | msigdb_gomf | 134,6,10,14,178,20,118,209 | 1700,1475,556,855,875,209,1590,1801,432,1445,558,931,6,835,14,2409,1842,596,810,962,1003,1136,1388,910,1526,1347,118,387,1996,888,20,10,1724,1580,665,515,134,920,178,1179,292 | -0.4212859664531922,-0.27218882129392213,0.4848802844441598,0.16759443900767257,0.14556503368975818,1.1786210307382605,-0.34606944879987256,-0.49788927155059765,0.6448072914475071,-0.24785041714148484,0.4848802844441598,0.10115585811536389,4.254918317045912,0.18950873816397323,3.796269049554577,-1.615882187826786,-0.52... | 2,468 |
Cellular lipid metabolic process | 49 | 158 | 2.75085 | 0.005944 | Q8N4Q0,P54646,Q5H8A4,Q9BT22,Q15067,O95470,P14174,P16278,P07602,Q16134,P40939,Q9HB40,Q8WTV0,P50897,Q9NPH2,Q9BZF1,P23786,P11310,P04062,Q99805,O75844,Q96N66,P06280,Q8NF37,P04066,Q9NZ01,P07099,Q16739,P16435,Q96G23,Q9P035,O15121,Q06136,Q16836,O15269,O75874,Q9UBF8,Q9Y263,P06865,Q96EB6,Q6NUM9,Q13510,Q15800,O60678,Q9NPH0,P3579... | Processes and pathways | GO Biological process | msigdb_gobp | 1,383,139,140,400,143,280,25,28,31,33,34,36,39,168,172,293,175,49,182,185,316,187,315,189,70,199,72,326,78,214,86,97,351,223,104,106,366,232,362,239,112,114,244,251,119,245,123,388 | 521,2113,123,2448,2453,1052,2320,86,223,556,925,244,1956,2114,1226,698,185,104,2345,143,1544,245,49,189,1292,2449,2070,187,232,199,28,1546,175,1627,2209,280,496,1928,2433,25,326,395,805,2182,293,2298,2094,860,1370,1333,2212,580,994,995,119,1296,2299,33,1768,1512,765,1197,594,1965,39,2124,441,878,1129,1772,1098,383,2167... | 0.5254338786156286,-0.7915396678024824,1.6837858907333896,-2.4782507088829866,-2.6900423224636016,0.0108995245257502,-1.137659851909859,2.023552801349019,1.1264079353050018,0.4848802844441598,0.10115585811536389,1.0557791765577014,-0.6287910407099505,-0.7915396678024824,-0.10473033469147558,0.3186451392955738,1.3148080... | 2,468 |
Endoplasmic reticulum to golgi vesicle mediated transport | 19 | 53 | 2.747955 | 0.005997 | Q15363,Q9P2W9,P24390,Q15437,Q969M3,Q9Y282,P35606,P62820,Q9HCU5,P18085,Q9Y3B3,Q92538,Q15436,O15027,Q9Y3Q3,Q08379,Q9HD26,P49257,Q13618 | Processes and pathways | GO Biological process | msigdb_gobp | 384,129,3,133,403,13,411,420,312,436,206,471,218,466,356,483,364,111,372 | 1474,1026,490,466,1703,632,1476,1956,1925,1228,2179,436,3,411,1417,111,684,1375,1271,1272,1097,1039,2074,420,483,1133,730,372,384,218,133,2025,813,660,1693,471,1010,403,1857,973,1319,312,364,917,1438,129,2154,13,1223,206,356,1954,609 | -0.27218882129392213,0.033646699417906,0.565601265268559,0.6053899682620425,-0.4212859664531922,0.4025832237568715,-0.27218882129392213,-0.6287910407099505,-0.6022778524744863,-0.10473033469147558,-0.8753826232126409,0.6448072914475071,4.4061529638753205,0.6838603272070093,-0.22365336069552152,1.7750387384721054,0.3397... | 2,468 |
Outer membrane | 15 | 68 | 2.739468 | 0.006154 | O43169,P21796,Q9NZ45,Q8NBU5,Q9UBF8,P45880,Q6NUM9,Q99720,O96008,Q8N4H5,Q9UBM7,Q9Y277,Q8N0X7,Q9NS69,O00429 | Localization | GO Cellular component | msigdb_gocc | 5,6,71,171,106,14,239,80,267,177,51,178,249,57,152 | 1182,152,2453,5,779,925,2352,2007,1507,1361,1544,267,1798,2310,1905,1668,1629,6,1293,994,2388,1037,1373,14,809,582,2167,350,1914,731,1490,882,768,1389,1138,944,239,527,1918,1278,249,177,1650,171,1853,2431,773,2177,311,2192,80,1214,1015,2136,820,1018,57,1401,454,1726,71,388,106,51,178,1116,797,554 | -0.08134699713241711,1.4952459017765753,-2.6900423224636016,4.254918317045912,0.2329969417200938,0.10115585811536389,-1.228940433793697,-0.6823322307636482,-0.29667029004619083,-0.1995959661077008,-0.32129657210781537,1.002027140929854,-0.49788927155059765,-1.1076784324720763,-0.5759332603866829,-0.3960622793653552,-0.... | 2,468 |
Transport to the golgi and subsequent modification | 27 | 64 | 2.738362 | 0.006175 | Q15363,P24390,Q13561,P47756,P35606,Q12955,P61923,P62820,Q9HCU5,P49755,P04066,P18085,O75935,Q14203,Q9Y3B3,Q9UJW0,Q9Y678,Q92538,Q15436,O15027,Q9Y3Q3,Q08379,Q14789,P49257,P63167,Q12893,O14653 | Processes and pathways | Reactome Pathways | msigdb_reactome | 384,3,273,653,411,546,544,420,312,684,189,436,431,583,206,215,609,471,218,466,356,483,233,111,616,618,490 | 1474,1026,490,778,466,1703,1476,1925,431,1228,189,1231,436,3,411,1676,1095,653,1417,111,684,1377,1272,1097,1039,2215,1556,544,420,616,1241,1302,483,618,1133,546,730,1134,273,998,1604,583,1566,233,384,218,2025,1253,1693,471,1010,1045,1857,713,1973,1110,973,1319,312,215,206,356,609,1264 | -0.27218882129392213,0.033646699417906,0.565601265268559,0.2329969417200938,0.6053899682620425,-0.4212859664531922,-0.27218882129392213,-0.6022778524744863,0.6448072914475071,-0.10473033469147558,1.281166698194264,-0.10473033469147558,0.6448072914475071,4.4061529638753205,0.6838603272070093,-0.3960622793653552,-0.01197... | 2,468 |
Mitochondrion organization | 32 | 142 | 2.701848 | 0.006896 | Q9H270,Q99595,P21796,Q9Y241,P45880,Q9Y2R0,O96008,O14925,O00429,Q6DKK2,O75153,P78310,O43676,P14406,P39210,P04062,Q8N4H5,Q99536,Q9H061,O95169,Q9NS69,Q69YU5,Q5JRX3,Q00535,Q9UDX5,Q15070,Q16543,P50851,Q13505,P55786,P49257,Q9Y6M9 | Processes and pathways | GO Biological process | msigdb_gobp | 257,4,6,137,14,142,267,266,152,155,37,294,45,170,302,49,177,311,55,305,57,60,196,328,208,210,211,225,350,110,111,254 | 349,798,152,555,266,854,45,1120,779,37,2069,2373,984,2352,2007,1730,1957,699,1360,1507,1361,393,305,761,1229,856,700,410,267,2142,591,49,1799,1590,1031,1905,1547,701,2399,1090,558,170,804,6,1806,2367,1807,2347,1124,1293,1268,2213,1675,2388,302,1512,14,2419,111,2250,704,1336,225,1375,582,1678,110,1715,1061,294,2020,328,... | 0.7799438888928811,0.21130916709284053,1.4952459017765753,0.4848802844441598,1.002027140929854,0.16759443900767257,2.7177266378332408,-0.03496930883195915,0.2329969417200938,2.8723301020860834,-0.7365753446833382,-1.3538973144414643,0.05627090662211817,-1.228940433793697,-0.6823322307636482,-0.44666371637530605,-0.6287... | 2,468 |
Organic anion transport | 16 | 44 | 2.693324 | 0.007074 | Q99808,Q9UBX3,Q7L0J3,O43808,O60831,Q9H2D1,Q9HC21,P21359,Q15042,P12235,Q8TB61,P14174,P04920,P07602,Q9Y619,Q9NZJ7 | Processes and pathways | GO Biological process | msigdb_gobp | 387,134,38,556,480,10,515,144,444,558,118,280,209,28,292,388 | 556,480,855,1731,875,1292,209,1590,1800,28,1801,1445,558,931,280,144,860,835,1842,596,810,962,1003,881,444,1136,1526,1347,38,118,387,1996,888,10,1724,1580,665,515,388,134,1219,920,1179,292 | 0.4848802844441598,0.5855424906777212,0.16759443900767257,-0.44666371637530605,0.14556503368975818,-0.15189356987392963,1.1786210307382605,-0.34606944879987256,-0.49788927155059765,3.198719452250958,-0.49788927155059765,-0.24785041714148484,0.4848802844441598,0.10115585811536389,0.9839576617525956,1.5431638652413855,0.... | 2,468 |
Receptor | 9 | 20 | 2.673382 | 0.007509 | Q8WTV0,Q9BUN8,A6NIH7,P39210,Q9ULC4,Q9UQB8,Q14108,Q9HCD5,Q567V2 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 36,274,11,302,341,22,87,158,96 | 11,1403,2037,1506,985,2038,1979,1800,433,302,87,686,96,36,603,274,347,158,341,22 | 3.926954124542245,-0.22365336069552152,-0.7093648604789845,-0.29667029004619083,0.05627090662211817,-0.7093648604789845,-0.6554750699704857,-0.49788927155059765,0.6448072914475071,0.9292833665100879,2.0093242006690732,0.33978721059520445,1.9374688026168079,2.8839991952794084,0.4439327299123976,1.002027140929854,0.79890... | 2,468 |
Regulation of autophagy | 17 | 76 | 2.670386 | 0.007576 | Q93050,P54646,O15269,Q00535,P21796,Q9NZ45,Q96EB6,P19474,P04062,P40763,P09429,O75844,O00429,P07602,P10619,Q9Y487,Q9NZJ7 | Processes and pathways | GO Biological process | msigdb_gobp | 68,383,223,328,6,71,362,46,49,188,357,185,152,28,61,62,388 | 1977,152,696,223,1053,1925,953,185,1958,49,1903,1799,2246,1590,1763,28,1087,1802,357,1668,61,1331,558,1411,46,804,1446,2290,6,1123,1293,542,188,1037,2263,2250,704,383,1299,1058,1426,1743,328,963,1384,483,1816,634,1002,444,968,641,642,884,1650,1693,68,362,1994,2057,1434,1109,948,1216,774,1018,1050,71,388,2033,738,407,48... | -0.6554750699704857,1.4952459017765753,0.3186451392955738,1.1264079353050018,0.0108995245257502,-0.6022778524744863,0.07877351189206046,1.3148080906459898,-0.6287910407099505,2.644481441197411,-0.5759332603866829,-0.49788927155059765,-0.9609652532252494,-0.34606944879987256,-0.4721974863524341,3.198719452250958,-0.0119... | 2,468 |
Mental deterioration | 14 | 78 | 2.67037 | 0.007577 | O75503,Q9UBB4,P50897,P06865,Q13510,P04062,Q9BQE5,O95470,O96008,Q14108,P16278,O00429,P07602,Q9Y487 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,258,39,232,112,49,18,143,267,87,25,152,28,62 | 152,696,1475,1120,779,2228,896,984,32,1361,305,2296,143,267,2322,49,782,1231,232,28,1546,2039,1804,495,25,1479,395,933,2415,720,651,1034,834,1448,561,936,542,1373,611,1237,39,837,2124,1200,612,2074,1715,1423,1132,1202,963,1384,1063,1562,112,87,583,748,1569,944,1821,1570,1572,1650,1392,1578,623,2057,1434,2178,18,516,206... | 1.4952459017765753,0.3186451392955738,-0.27218882129392213,-0.03496930883195915,0.2329969417200938,-0.9322398063664452,0.12341926582388701,0.05627090662211817,3.010346969899404,-0.1995959661077008,0.9109010031706256,-1.0779141700680717,1.5431638652413855,1.002027140929854,-1.137659851909859,2.644481441197411,0.23299694... | 2,468 |
Incoordination | 12 | 58 | 2.657107 | 0.007881 | O75503,Q9UBB4,P40939,O14773,Q69YN2,O00754,Q01105,Q13510,Q6DKK2,P04062,P27635,P07602 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,258,33,94,201,231,145,112,155,49,85,28 | 2337,231,94,853,778,1475,1120,896,1956,32,985,1361,49,538,28,1625,558,1478,720,85,1448,936,499,33,1596,1157,1842,2074,2167,1057,1423,145,963,2218,964,1063,112,1460,1566,400,1914,201,155,1570,1572,1782,1528,1890,1011,2057,2178,1286,388,258,1895,1113,2243,292 | -1.167861727972861,1.1088603313127976,1.9374688026168079,0.16759443900767257,0.2329969417200938,-0.27218882129392213,-0.03496930883195915,0.12341926582388701,-0.6287910407099505,3.010346969899404,0.05627090662211817,-0.1995959661077008,2.644481441197411,0.5052058365472561,3.198719452250958,-0.3709907348752914,0.4848802... | 2,468 |
Vesicles | 33 | 211 | 2.65114 | 0.008022 | Q8N4Q0,P24390,Q15437,P42785,P30519,Q9NR09,P07858,P16278,Q9HD45,O00429,P07602,Q8WTV0,O75153,P50897,O95772,Q9BZF1,P10619,Q9Y487,P61201,P04066,O15127,Q93050,Q9NRY5,Q9HD20,Q15436,Q96J02,Q3SXM5,O15143,O76062,O00754,Q9UMR5,P49257,Q8TB61 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 1,3,133,17,21,150,24,25,154,152,28,36,37,39,41,172,61,62,190,189,194,68,69,81,218,228,98,101,102,231,108,111,118 | 521,152,231,465,610,1403,285,778,331,696,631,194,101,2037,649,2140,480,37,896,927,1406,1442,102,2346,2038,1228,2296,41,1979,1589,189,1903,232,28,24,2207,1624,1906,494,61,1960,433,1592,1091,1628,988,25,326,395,680,1446,651,3,992,1929,703,1872,21,994,1236,808,542,959,2014,1037,17,682,1450,1297,653,1417,960,111,1198,39,12... | 0.5254338786156286,1.4952459017765753,1.1088603313127976,0.6053899682620425,0.4233087298229898,-0.22365336069552152,0.9658109974394301,0.2329969417200938,0.8365644866172669,0.3186451392955738,0.4025832237568715,1.2642460462437752,1.8937737203521074,-0.7093648604789845,0.3817551739233301,-0.8192985310386937,0.5855424906... | 2,468 |
Vesicle membrane | 55 | 197 | 2.643186 | 0.008213 | Q9H270,Q15363,P24390,Q99816,Q15437,Q9UNH7,Q8N511,P42785,Q9UIQ6,P30519,O00429,P07602,Q15904,P35606,Q8WTV0,Q7L0J3,O95772,Q07065,P10321,O43493,P62820,A4D1P6,Q99805,P42892,Q8NF37,Q8N668,Q9Y487,O43760,O15127,Q93050,O00461,P11717,Q9Y2T2,O14964,Q7Z3T8,Q9Y3B3,Q9H0U3,Q92542,O15121,Q14108,Q15436,Q86Y82,Q8IV08,O15027,Q96J02,Q9Y3Q... | Localization | GO Cellular component | msigdb_gocc | 257,384,3,264,133,407,16,17,19,21,152,28,290,411,36,38,41,295,418,169,420,174,182,56,315,314,62,320,194,68,193,433,336,330,460,206,335,339,86,87,218,469,92,466,228,356,465,352,234,480,364,111,490,246,388 | 174,1584,1833,798,1182,152,193,1026,1586,490,465,330,466,696,86,631,194,1978,1703,169,717,2037,1900,320,1441,2068,1587,926,780,1476,480,760,896,1956,1406,1925,953,985,2038,1228,41,1979,591,1292,900,1800,2206,28,2180,2207,954,701,494,418,1960,1090,1669,433,2040,934,1232,680,1364,858,3,703,2161,2327,21,2120,411,1236,1633... | 1.3481865209735655,-0.34606944879987256,-0.5237411060737124,0.21130916709284053,-0.08134699713241711,1.4952459017765753,1.2642460462437752,0.033646699417906,-0.34606944879987256,0.565601265268559,0.6053899682620425,0.8365644866172669,0.6053899682620425,0.3186451392955738,2.023552801349019,0.4025832237568715,1.264246046... | 2,468 |
Cognitive impairment | 24 | 137 | 2.629244 | 0.008557 | Q9UBB4,Q15437,Q9Y2R0,P49770,O95470,Q9BQE5,P21359,O96008,P16278,O00429,O75569,Q6DKK2,P07602,O75503,P50897,P04062,P06280,Q9Y487,Q99720,Q14108,P06865,Q13510,Q6PGP7,Q8N0X7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 258,133,142,270,143,18,144,267,25,152,277,155,28,32,39,49,187,62,80,87,232,112,242,249 | 152,778,696,1475,1120,779,2228,896,984,1506,32,277,1361,305,2296,143,700,267,2322,49,782,1231,1799,187,232,28,1546,832,2039,1804,495,1445,558,25,1479,395,933,1671,2415,1480,144,720,651,858,1034,834,1448,2095,561,936,542,592,1037,1373,611,682,1374,594,1237,270,39,837,2124,878,672,1200,612,2074,1715,1273,1239,2348,1423,1... | 1.4952459017765753,0.2329969417200938,0.3186451392955738,-0.27218882129392213,-0.03496930883195915,0.2329969417200938,-0.9322398063664452,0.12341926582388701,0.05627090662211817,-0.29667029004619083,3.010346969899404,0.9839576617525956,-0.1995959661077008,0.9109010031706256,-1.0779141700680717,1.5431638652413855,0.3186... | 2,468 |
er | 24 | 72 | 2.616543 | 0.008883 | Q15363,Q9P2W9,Q969M3,O95470,Q9NQC3,Q969V3,O96005,Q07065,Q9BZF1,Q15392,Q00765,Q96N66,Q8NF37,Q9Y487,Q14739,P18085,Q9Y5M8,Q96GC9,O15121,Q16513,Q8N4V1,Q06136,O15269,Q16850 | Localization | OpenCell Localization | opencell_localization | 384,129,403,143,149,30,159,295,172,47,307,316,315,62,63,436,195,473,86,226,352,97,223,121 | 1182,1052,2320,86,739,223,1956,1925,1731,2179,143,159,1798,901,1443,1508,493,436,1234,1710,1633,523,1197,684,726,1375,2074,1638,1454,2168,1936,307,97,295,674,730,63,2381,881,384,47,2437,226,121,1390,1347,2189,737,352,1608,1465,315,660,845,1693,403,30,816,473,316,1997,172,1048,1538,149,917,474,1438,129,1081,62,195 | -0.08134699713241711,0.0108995245257502,-1.137659851909859,2.023552801349019,0.27603929431054613,1.1264079353050018,-0.6287910407099505,-0.6022778524744863,-0.44666371637530605,-0.8753826232126409,1.5431638652413855,1.4467856585109506,-0.49788927155059765,0.12341926582388701,-0.24785041714148484,-0.29667029004619083,0.... | 2,468 |
Metallopeptidase activity | 9 | 35 | 2.6097 | 0.009062 | Q5JRX3,P09960,P55786,Q9UIQ6,P50579,P42892,O75844,P52888,Q969V3 | Functions | GO Molecular function | msigdb_gomf | 196,103,110,19,52,56,185,58,30 | 825,1794,826,557,1730,185,829,591,103,2208,467,1233,2368,1483,56,52,511,58,110,1063,196,1492,1607,790,604,30,2058,817,275,850,2256,1614,1505,19,2067 | 0.18950873816397323,-0.49788927155059765,0.18950873816397323,0.4848802844441598,-0.44666371637530605,1.3148080906459898,0.18950873816397323,0.4439327299123976,1.8643955467119475,-0.9037132041831669,0.6053899682620425,-0.10473033469147558,-1.322298943353699,-0.27218882129392213,2.5069145047989934,2.5824892901533407,0.54... | 2,468 |
Sphingolipid metabolism | 7 | 9 | 2.604541 | 0.0092 | Q06136,Q9NZ01,Q16739,Q13510,P04062,O95470,P07602 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 97,70,72,112,49,143,28 | 223,143,49,28,395,97,112,72,70 | 1.1264079353050018,1.5431638652413855,2.644481441197411,3.198719452250958,0.7032523978558017,1.9229529370253255,1.7750387384721054,2.312020878410862,2.3252895643479303 | 2,468 |
Ion transport | 39 | 176 | 2.595116 | 0.009456 | Q99808,P54105,Q9UBX3,P21796,Q9NZJ7,Q9UNH7,Q9H2D1,P45880,P62942,O96008,P21359,P23634,Q9C0H2,Q9UDW1,P14174,O00429,P07602,Q9Y619,P08183,Q7L0J3,Q70HW3,Q9UHG3,O75964,Q9Y277,O75844,Q8N668,P61201,Q00535,O43772,Q9H0U3,Q9HD20,P04920,Q13423,Q8N4V1,P24941,Q9HC07,Q9HD26,Q8TB61,P78417 | Processes and pathways | GO Biological process | msigdb_gobp | 387,255,134,6,388,407,10,14,271,267,144,396,20,151,280,152,28,292,286,38,40,44,50,178,185,314,190,328,77,335,81,209,344,352,224,234,364,118,127 | 1833,1700,152,1834,739,1475,522,77,556,873,1587,480,828,2005,2373,2352,1406,1730,855,185,1731,2115,50,761,875,267,2322,591,1292,1407,209,509,1707,1590,1800,1328,2206,1763,28,2180,286,1801,2091,432,701,1509,1445,2366,2458,558,931,857,702,280,394,1411,934,2093,1446,2290,1480,144,6,396,670,224,2441,703,1806,860,2347,1293,... | -0.5237411060737124,-0.4212859664531922,1.4952459017765753,-0.5237411060737124,0.27603929431054613,-0.27218882129392213,0.5254338786156286,2.1907384712256417,0.4848802844441598,0.14556503368975818,-0.34606944879987256,0.5855424906777212,0.18950873816397323,-0.6823322307636482,-1.3538973144414643,-1.228940433793697,-0.2... | 2,468 |
Er to golgi anterograde transport | 26 | 63 | 2.576189 | 0.00999 | Q15363,P24390,Q13561,P47756,P35606,Q12955,P61923,P62820,Q9HCU5,P49755,P18085,O75935,Q14203,Q9Y3B3,Q9UJW0,Q9Y678,Q92538,Q15436,O15027,Q9Y3Q3,Q08379,Q14789,P49257,P63167,Q12893,O14653 | Processes and pathways | Reactome Pathways | msigdb_reactome | 384,3,273,653,411,546,544,420,312,684,436,431,583,206,215,609,471,218,466,356,483,233,111,616,618,490 | 1474,1026,490,778,466,1703,1476,1925,431,1228,1231,436,3,411,1676,1095,653,1417,111,684,1377,1272,1097,1039,2215,1556,544,420,616,1241,1302,483,618,1133,546,730,1134,273,998,1604,583,1566,233,384,218,2025,1253,1693,471,1010,1045,1857,713,1973,1110,973,1319,312,215,206,356,609,1264 | -0.27218882129392213,0.033646699417906,0.565601265268559,0.2329969417200938,0.6053899682620425,-0.4212859664531922,-0.27218882129392213,-0.6022778524744863,0.6448072914475071,-0.10473033469147558,-0.10473033469147558,0.6448072914475071,4.4061529638753205,0.6838603272070093,-0.3960622793653552,-0.011972007198974987,0.38... | 2,468 |
Tchem | 51 | 245 | 2.564063 | 0.010345 | Q9H773,Q02818,P45880,P42785,O95470,Q9UIQ6,P30519,P14174,P07858,P16278,P43490,Q15904,P08183,Q13126,Q8WTV0,Q15257,Q14534,P23786,P04062,Q9UBM7,P50579,P42892,P08243,P40763,P10619,P04066,Q5JRX3,Q9NZ45,P07099,O15121,O60502,Q16513,Q9BTY2,O15269,P24941,P09960,O75874,Q9UBF8,P54136,O00754,P06865,A0AVT1,P55786,P42575,Q13510,O6072... | Drugs and Diseases | Pharos IDG Category | pharos_protein_category | 0,130,14,17,143,19,21,280,24,25,29,290,286,35,36,297,296,293,49,51,52,56,186,188,61,189,196,71,199,86,95,226,100,223,224,103,104,106,105,231,232,109,110,236,112,113,240,119,121,244,127 | 109,1440,231,2453,1052,777,610,86,1326,223,799,1797,2226,873,2227,95,244,113,698,104,1666,1188,143,1734,577,1589,1291,1902,49,189,2309,537,1903,1799,2246,1030,2310,783,232,199,2116,2452,1763,1546,832,24,1031,286,1189,186,1668,2039,103,61,1960,1445,2458,433,1627,987,2208,1478,1091,956,280,2181,1735,1266,434,467,2433,25,... | 1.7900609938314576,-0.24785041714148484,1.1088603313127976,-2.6900423224636016,0.0108995245257502,0.2329969417200938,0.4233087298229898,2.023552801349019,-0.17567657782693433,1.1264079353050018,0.21130916709284053,-0.49788927155059765,-0.9322398063664452,0.14556503368975818,-0.9322398063664452,1.9374688026168079,1.0557... | 2,468 |
Sphingolipid metabolism integrated pathway | 6 | 7 | 2.560247 | 0.01046 | Q06136,Q16739,Q96G23,Q13510,O95470,O15121 | Processes and pathways | WikiPathways | msigdb_wp | 97,72,78,112,143,86 | 86,223,143,97,112,72,78 | 2.023552801349019,1.1264079353050018,1.5431638652413855,1.9229529370253255,1.7750387384721054,2.312020878410862,2.1633192386683975 | 2,468 |
Sphingolipid metabolism overview | 6 | 7 | 2.560247 | 0.01046 | Q06136,Q16739,Q96G23,Q13510,O95470,O15121 | Processes and pathways | WikiPathways | msigdb_wp | 97,72,78,112,143,86 | 86,223,143,97,112,72,78 | 2.023552801349019,1.1264079353050018,1.5431638652413855,1.9229529370253255,1.7750387384721054,2.312020878410862,2.1633192386683975 | 2,468 |
Lipid binding | 31 | 106 | 2.5566 | 0.01057 | P21796,P05023,Q9UNH7,A6NIH7,P45880,Q15067,Q9BQE5,P21359,O00429,P07602,Q8WTV0,P50897,O95772,Q9BZF1,P04062,Q92643,Q7KZI7,Q9H6U6,Q8N668,P11717,O14964,Q7Z3T8,P28070,Q14108,Q92538,O14773,P37198,P09429,O95218,Q9UJZ1,Q9NZJ7 | Functions | GO Molecular function | msigdb_gomf | 6,509,407,11,14,400,18,144,152,28,36,39,41,172,49,449,446,318,314,433,330,460,457,87,471,94,499,357,492,519,388 | 11,1182,152,2320,94,330,778,696,739,799,717,1441,779,2068,780,760,2114,2345,2038,492,41,49,1292,509,2206,28,1444,2180,357,954,2399,1960,2366,433,1627,1232,144,6,805,2182,1332,457,1370,1481,1293,560,995,499,1193,14,1126,1416,960,39,742,1636,1678,1598,2074,1158,616,1339,1302,907,1989,87,1067,2024,400,1777,1718,1647,446,4... | 3.926954124542245,-0.08134699713241711,1.4952459017765753,-1.137659851909859,1.9374688026168079,0.8365644866172669,0.2329969417200938,0.3186451392955738,0.27603929431054613,0.21130916709284053,0.29739620791205207,-0.24785041714148484,0.2329969417200938,-0.7365753446833382,0.2329969417200938,0.2545732583950417,-0.791539... | 2,468 |
Abnormal conjunctiva morphology | 6 | 24 | 2.556225 | 0.010581 | P04066,Q15437,Q13510,P06280,P10619,Q14739 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 189,133,112,187,61,63 | 1619,591,189,1959,187,61,987,933,1671,720,957,457,1550,836,594,2045,225,1304,112,63,133,1012,1079,1505 | -0.3709907348752914,0.4439327299123976,1.281166698194264,-0.6287910407099505,1.2980205320115141,2.3910310244631345,0.05627090662211817,0.10115585811536389,-0.3960622793653552,0.29739620791205207,0.07877351189206046,0.6251446041977697,-0.32129657210781537,0.18950873816397323,0.4439327299123976,-0.7093648604789845,1.1264... | 2,468 |
Glycosphingolipid metabolism | 9 | 14 | 2.556151 | 0.010584 | Q16739,P06865,Q13510,P04062,P16278,P06280,P07602,P10619,Q9NZJ7 | Processes and pathways | Reactome Pathways | msigdb_reactome | 72,232,112,49,25,187,28,61,388 | 1475,49,187,232,28,1546,61,25,395,112,72,1997,1726,388 | -0.27218882129392213,2.644481441197411,1.2980205320115141,1.1088603313127976,3.198719452250958,-0.32129657210781537,2.3910310244631345,3.273996348775714,0.7032523978558017,1.7750387384721054,2.312020878410862,-0.6554750699704857,-0.4212859664531922,0.7225559645801342 | 2,468 |
Protein localization to mitochondrion | 10 | 47 | 2.548154 | 0.010829 | Q9H270,Q99595,Q5JRX3,P55786,P49257,O96008,Q8N4H5,Q15070,Q9NS69,O00429 | Processes and pathways | GO Biological process | msigdb_gobp | 257,4,196,110,111,267,177,210,57,152 | 349,798,152,555,266,854,1730,1507,1361,856,700,267,1031,701,2399,1090,1629,804,1124,1293,458,1268,111,2250,1375,582,110,1061,1063,210,731,1490,636,1389,196,1528,177,2135,4,257,1216,1860,57,919,1116,797,554 | 0.7799438888928811,0.21130916709284053,1.4952459017765753,0.4848802844441598,1.002027140929854,0.16759443900767257,-0.44666371637530605,-0.29667029004619083,-0.1995959661077008,0.16759443900767257,0.3186451392955738,1.002027140929854,0.033646699417906,0.3186451392955738,-1.5487932064905703,-0.011972007198974987,-0.3709... | 2,468 |
Glycoside hydrolase superfamily [IPR017853] | 6 | 14 | 2.542155 | 0.011017 | P04066,Q9BTY2,P04062,P16278,P06280,O60502 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 189,100,49,25,187,95 | 95,49,189,187,232,1546,1801,494,25,541,1200,1524,100,1215 | 1.9374688026168079,2.644481441197411,1.281166698194264,1.2980205320115141,1.1088603313127976,-0.32129657210781537,-0.49788927155059765,0.565601265268559,3.273996348775714,0.5052058365472561,-0.08134699713241711,-0.29667029004619083,1.9083880241673503,-0.08134699713241711 | 2,468 |
Oxidoreductase activity acting on the ch ch group of donors | 7 | 20 | 2.541516 | 0.011037 | Q8N4Q0,Q9NZ01,O76062,Q15392,P11310,Q9UBM7,Q14739 | Functions | GO Molecular function | msigdb_gomf | 1,70,102,47,175,51,63 | 102,175,720,2094,1448,1483,594,1965,1812,63,400,47,239,844,1,2423,1578,1613,70,51 | 1.8643955467119475,1.3481865209735655,0.29739620791205207,-0.7639661184612422,-0.24785041714148484,-0.27218882129392213,0.4439327299123976,-0.6287910407099505,-0.49788927155059765,2.364853829476893,0.7032523978558017,2.705604207310635,1.0912400876291406,0.18950873816397323,4.512284053224345,-1.7886042606720733,-0.32129... | 2,468 |
Copi mediated anterograde transport | 23 | 50 | 2.540141 | 0.011081 | Q15363,P24390,Q13561,P47756,P35606,Q12955,P61923,P62820,P49755,Q99747,P18085,O75935,Q14203,Q9Y3B3,Q9UJW0,Q9Y678,Q92538,Q9Y3Q3,Q08379,Q14789,P63167,Q12893,O14653 | Processes and pathways | Reactome Pathways | msigdb_reactome | 384,3,273,653,411,546,544,420,684,713,436,431,583,206,215,609,471,356,483,233,616,618,490 | 1026,490,778,1703,1476,431,1231,436,3,411,1676,1095,653,1417,684,1377,1272,1097,2215,1556,544,420,616,1241,1302,483,618,546,730,1134,273,998,1604,583,1566,233,384,1253,471,1045,713,1973,1110,973,1319,215,206,356,609,1264 | 0.033646699417906,0.565601265268559,0.2329969417200938,-0.4212859664531922,-0.27218882129392213,0.6448072914475071,-0.10473033469147558,0.6448072914475071,4.4061529638753205,0.6838603272070093,-0.3960622793653552,-0.011972007198974987,0.3817551739233301,-0.22365336069552152,0.33978721059520445,-0.1995959661077008,-0.12... | 2,468 |
Abnormal retinal artery morphology | 7 | 19 | 2.533562 | 0.011291 | P06865,Q13510,Q9Y4P3,P16278,P07602,P10619,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 232,112,380,25,28,61,388 | 1899,232,28,1546,61,1152,25,395,651,1295,1039,1773,112,1776,1072,889,388,1660,380 | -0.5759332603866829,1.1088603313127976,3.198719452250958,-0.32129657210781537,2.3910310244631345,-0.058093817935866696,3.273996348775714,0.7032523978558017,0.3817551739233301,-0.15189356987392963,0.033646699417906,-0.4721974863524341,1.7750387384721054,-0.4721974863524341,0.0108995245257502,0.14556503368975818,0.722555... | 2,468 |
Secondary alcohol metabolic process | 10 | 37 | 2.532582 | 0.011323 | Q8WTV0,P48735,O76062,O75874,Q15392,P04062,Q9BQE5,Q9UBM7,Q15800,Q14739 | Processes and pathways | GO Biological process | msigdb_gobp | 36,66,102,104,47,49,18,51,114,63 | 696,2138,2114,104,102,1798,49,2458,496,326,1838,995,1296,1512,1197,66,1965,2279,1934,1129,1772,383,1339,1680,1884,296,63,2370,47,2437,114,121,36,2365,18,51,775 | 0.3186451392955738,-0.8192985310386937,-0.7915396678024824,1.8496309709719285,1.8643955467119475,-0.49788927155059765,2.644481441197411,-3.001354480809533,0.565601265268559,0.8552711400416021,-0.5237411060737124,0.05627090662211817,-0.15189356987392963,-0.29667029004619083,-0.08134699713241711,2.338517782432342,-0.6287... | 2,468 |
Hydrolase activity hydrolyzing o glycosyl compounds | 11 | 16 | 2.529815 | 0.011412 | Q9NUJ1,P04066,Q9BTY2,O00754,P06865,P04062,P17900,P10253,P16278,P06280,O60502 | Functions | GO Molecular function | msigdb_gomf | 517,189,100,231,232,49,395,494,25,187,95 | 231,95,49,189,187,232,1546,494,25,395,541,1200,1716,1524,100,517 | 1.1088603313127976,1.9374688026168079,2.644481441197411,1.281166698194264,1.2980205320115141,1.1088603313127976,-0.32129657210781537,0.565601265268559,3.273996348775714,0.7032523978558017,0.5052058365472561,-0.08134699713241711,-0.4212859664531922,-0.29667029004619083,1.9083880241673503,0.5455653723813071 | 2,468 |
Intra golgi and retrograde golgi to er traffic | 32 | 77 | 2.528932 | 0.011441 | Q9P2W9,Q15363,P24390,O43264,Q8TD16,Q8TBA6,Q13561,P47756,P35606,P61923,Q07866,Q12981,P62820,O43493,P49755,Q15042,P18085,O00461,P11717,Q14203,O75935,Q9Y3B3,Q9UJW0,Q9Y678,Q92538,Q10472,Q9Y3Q3,P40616,P63167,O14653,Q9NSK0,P52732 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,384,3,632,661,402,273,653,411,544,673,674,420,169,684,444,436,193,433,583,431,206,215,609,471,468,356,358,616,490,122,371 | 2225,193,1026,490,1703,632,169,1900,926,1925,431,1188,898,1231,433,436,1364,3,1094,411,358,765,1676,1095,653,1417,684,371,1377,1678,1272,1097,2215,1556,544,420,616,1241,1426,905,673,1882,468,864,674,730,1134,273,1604,583,1566,1567,444,1778,384,1253,402,661,471,1045,1212,713,1973,1110,973,1016,1319,948,1048,122,129,2088... | -0.9322398063664452,1.2642460462437752,0.033646699417906,0.565601265268559,-0.4212859664531922,0.4025832237568715,1.38130620151236,-0.5759332603866829,0.10115585811536389,-0.6022778524744863,0.6448072914475071,-0.08134699713241711,0.12341926582388701,-0.10473033469147558,0.6448072914475071,0.6448072914475071,-0.1995959... | 2,468 |
Golgi to er retrograde transport | 26 | 65 | 2.525103 | 0.011566 | Q15363,Q9P2W9,P24390,O43264,Q8TD16,Q13561,P47756,P35606,P61923,Q07866,Q12981,P62820,P49755,Q15042,P18085,O75935,Q14203,Q9Y3B3,Q9UJW0,Q9Y678,Q92538,Q10472,Q9Y3Q3,P63167,Q9NSK0,P52732 | Processes and pathways | Reactome Pathways | msigdb_reactome | 384,129,3,632,661,273,653,411,544,673,674,420,684,444,436,431,583,206,215,609,471,468,356,616,122,371 | 2225,1026,632,1925,431,1188,898,1231,436,1364,3,1094,411,765,1676,1095,653,1417,684,371,1377,1272,1097,2215,1556,544,420,616,1241,1426,905,673,1882,468,864,674,1134,273,1604,583,1566,1567,444,1778,384,1253,661,471,1045,1212,713,1973,1110,973,1016,1319,948,1048,122,129,215,206,356,609,1264 | -0.9322398063664452,0.033646699417906,0.4025832237568715,-0.6022778524744863,0.6448072914475071,-0.08134699713241711,0.12341926582388701,-0.10473033469147558,0.6448072914475071,-0.1995959661077008,4.4061529638753205,-0.011972007198974987,0.6838603272070093,0.2545732583950417,-0.3960622793653552,-0.011972007198974987,0.... | 2,468 |
Hallucinations | 9 | 36 | 2.522793 | 0.011643 | O75503,P50897,O00754,P07602,P04062,Q9BQE5,Q8N0X7,O00429,Q6DKK2 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 32,39,231,28,49,18,249,152,155 | 1898,152,231,1475,779,896,32,267,49,28,1982,1593,651,1984,561,1483,682,39,2416,672,2074,1239,963,2283,1562,1568,155,1572,249,1650,2057,1434,18,1075,388,920 | -0.5759332603866829,1.4952459017765753,1.1088603313127976,-0.27218882129392213,0.2329969417200938,0.12341926582388701,3.010346969899404,1.002027140929854,2.644481441197411,3.198719452250958,-0.6554750699704857,-0.34606944879987256,0.3817551739233301,-0.6554750699704857,0.4848802844441598,-0.27218882129392213,0.33978721... | 2,468 |
Vacuole organization | 15 | 42 | 2.509808 | 0.01208 | Q9H270,O75503,O14773,P50851,P11117,P50897,Q9HC07,P62820,Q8N511,P04062,Q15042,P16615,Q96GC9,Q14108,Q86Y82 | Processes and pathways | GO Biological process | msigdb_gobp | 257,32,94,225,167,39,234,420,16,49,444,394,473,87,469 | 798,94,1925,32,985,1361,49,2206,1546,494,167,1331,394,680,1037,225,39,2123,1678,1200,1641,420,87,444,1718,2171,469,16,1693,1012,622,473,1994,2057,1319,587,257,948,234,759,1864,1116 | 0.21130916709284053,1.9374688026168079,-0.6022778524744863,3.010346969899404,0.05627090662211817,-0.1995959661077008,2.644481441197411,-0.9037132041831669,-0.32129657210781537,0.565601265268559,1.3977702991328884,-0.17567657782693433,0.7032523978558017,0.33978721059520445,0.033646699417906,1.1264079353050018,2.81351289... | 2,468 |
Glycosidase | 7 | 15 | 2.498267 | 0.01248 | P04066,Q9BTY2,O00754,P04062,P16278,P06280,O60502 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 189,100,231,49,25,187,95 | 231,2226,95,49,189,187,232,1546,494,25,541,1200,1716,1524,100 | 1.1088603313127976,-0.9322398063664452,1.9374688026168079,2.644481441197411,1.281166698194264,1.2980205320115141,1.1088603313127976,-0.32129657210781537,0.565601265268559,3.273996348775714,0.5052058365472561,-0.08134699713241711,-0.4212859664531922,-0.29667029004619083,1.9083880241673503 | 2,468 |
Sterol metabolic process | 8 | 32 | 2.495975 | 0.012561 | Q8WTV0,O76062,Q15392,P04062,Q9BQE5,Q9UBM7,Q15800,Q14739 | Processes and pathways | GO Biological process | msigdb_gobp | 36,102,47,49,18,51,114,63 | 696,2114,102,1798,49,2458,496,326,1838,995,1296,1512,1197,1965,1129,1772,383,1339,1680,1884,296,63,2370,47,2437,114,121,36,18,51,775,1219 | 0.3186451392955738,-0.7915396678024824,1.8643955467119475,-0.49788927155059765,2.644481441197411,-3.001354480809533,0.565601265268559,0.8552711400416021,-0.5237411060737124,0.05627090662211817,-0.15189356987392963,-0.29667029004619083,-0.08134699713241711,-0.6287910407099505,-0.03496930883195915,-0.4721974863524341,0.7... | 2,468 |
Corneal opacity | 17 | 42 | 2.491321 | 0.012727 | P04066,O43505,Q06136,O75844,O60566,P53701,O00754,Q5H8A4,P06280,Q13510,P04062,Q9UBM7,Q9Y4P3,P52732,P16278,O75569,P10619 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 189,409,97,185,430,59,231,139,187,112,49,51,380,371,25,277,61 | 231,853,409,1358,430,1620,1506,277,185,761,1705,2142,49,189,187,1088,61,25,933,1671,1295,936,592,441,371,59,612,1773,1275,2463,97,2369,112,1776,767,1248,139,1526,796,51,1660,380 | 1.1088603313127976,0.16759443900767257,0.6838603272070093,-0.1995959661077008,0.6448072914475071,-0.3709907348752914,-0.29667029004619083,0.9839576617525956,1.3148080906459898,0.2545732583950417,-0.4212859664531922,-0.8192985310386937,2.644481441197411,1.281166698194264,1.2980205320115141,-0.011972007198974987,2.391031... | 2,468 |
Tetratricopeptide-like helical domain superfamily [IPR011990] | 23 | 71 | 2.489119 | 0.012806 | Q9H270,Q6ZXV5,Q9UJX3,O75718,Q6DKK2,Q9Y6X3,O00231,O75153,Q9Y5Q9,Q13325,P61201,Q96EK5,O00411,Q9UJX4,O00170,A0AVF1,Q9Y262,Q96BR5,Q6PGP7,Q9Y5A7,Q9NSK0,Q9BXJ9,Q9UBV2 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 257,528,406,392,155,165,284,37,429,443,190,329,84,488,349,222,235,360,242,253,122,125,518 | 222,349,284,84,1026,574,799,575,924,37,392,1187,1507,2009,1230,1091,1371,1267,1037,1373,725,1198,1636,2215,190,1132,1681,673,1242,1815,1883,1744,443,1459,1646,1944,2381,706,1167,1490,1069,155,1823,242,528,710,846,360,329,1694,2177,1316,867,713,125,1318,257,1353,1173,1581,122,626,518,533,406,488,235,1148,253,429,165 | 1.1264079353050018,0.7799438888928811,0.9658109974394301,2.0659594259261063,0.033646699417906,0.4644562459753665,0.21130916709284053,0.4644562459753665,0.10115585811536389,2.8723301020860834,0.7032523978558017,-0.08134699713241711,-0.29667029004619083,-0.6823322307636482,-0.10473033469147558,-0.011972007198974987,-0.19... | 2,468 |
Organophosphate ester transport | 10 | 20 | 2.455434 | 0.014071 | Q99808,P08183,Q8WTV0,Q9H2D1,Q9BZF1,Q96GC9,P12235,Q8TB61,Q14108,Q9HC21 | Processes and pathways | GO Biological process | msigdb_gobp | 387,286,36,10,172,473,558,118,87,515 | 556,1590,286,558,931,805,2182,835,960,87,1388,1526,118,36,473,387,172,10,515,1438 | 0.4848802844441598,-0.34606944879987256,0.9658109974394301,0.4848802844441598,0.10115585811536389,0.21130916709284053,-0.8753826232126409,0.18950873816397323,0.07877351189206046,2.0093242006690732,-0.1995959661077008,-0.29667029004619083,1.7296545033561892,2.8839991952794084,0.6053899682620425,0.7225559645801342,1.3813... | 2,468 |
Transferase | 83 | 249 | 2.454484 | 0.014109 | P17858,Q6ZXV5,Q9BV86,O75150,Q7L0Y3,P46977,P43490,P40939,Q13126,P04183,P30876,P35573,Q9UKN8,P19474,P04062,Q5VV42,Q06203,P52789,Q16739,O95819,P34896,P22102,Q96G23,Q9HC36,O00411,Q8N6R0,P51003,P49327,P48729,Q14258,Q2TAA5,Q9ULT8,Q9UBF8,O14976,O60725,Q8NCH0,Q86UY6,P35790,O00116,P78417,P49366,Q5H8A4,Q9BT22,Q9NR09,P11802,Q9NRN... | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 510,528,9,12,529,523,29,33,35,537,539,541,573,46,49,566,563,582,72,577,76,578,78,606,84,602,595,594,593,598,620,628,106,610,113,115,117,119,123,127,138,139,140,150,153,197,213,228,226,223,224,244,261,281,293,316,315,322,328,333,351,363,362,359,374,385,383,381,398,390,391,409,447,446,445,452,437,430,468,487,482,498,496 | 123,84,2320,777,853,381,390,610,1326,223,799,391,1703,1185,409,697,430,244,113,12,2141,874,1958,1477,1086,856,1734,577,1705,2245,1291,2323,1902,49,2309,537,1903,1030,783,2071,1362,1547,1088,1804,1626,930,153,1592,955,2159,496,1735,932,1907,1411,510,1629,46,989,437,804,1737,651,1412,578,2182,762,1154,293,2262,2298,224,8... | 1.6837858907333896,2.0659594259261063,-1.137659851909859,0.2329969417200938,0.16759443900767257,0.7225559645801342,0.7032523978558017,0.4233087298229898,-0.17567657782693433,1.1264079353050018,0.21130916709284053,0.7032523978558017,-0.4212859664531922,-0.08134699713241711,0.6838603272070093,0.3186451392955738,0.6448072... | 2,468 |
golgi | 27 | 56 | 2.454262 | 0.014117 | O15126,Q15437,Q969M3,Q9BXB4,Q9Y3P9,P35606,O75122,Q15904,P61923,O15258,P62820,Q8IXU6,P49755,Q9Y487,Q15907,O15127,P18085,Q8IZA0,Q9NTJ5,Q9Y678,Q92538,Q15436,Q08379,Q9UBF8,O14976,P40616,O14653 | Localization | OpenCell Localization | opencell_localization | 631,133,403,532,669,411,160,290,544,166,420,43,684,62,707,194,436,323,474,609,471,218,483,106,610,358,490 | 1026,490,2320,610,631,194,166,160,985,1228,2179,2207,436,805,411,358,684,1678,1598,1097,1039,2215,2168,544,420,1132,1275,483,730,1067,218,133,290,707,813,43,323,1253,1693,471,403,1753,532,1319,948,892,917,474,1438,1471,106,1081,1116,669,62,609 | 0.033646699417906,0.565601265268559,-1.137659851909859,0.4233087298229898,0.4025832237568715,1.2642460462437752,1.3977702991328884,1.430509532064174,0.05627090662211817,-0.10473033469147558,-0.8753826232126409,-0.9037132041831669,0.6448072914475071,0.21130916709284053,0.6838603272070093,0.7609008970028596,0.33978721059... | 2,468 |
Hormone metabolic process | 12 | 24 | 2.451794 | 0.014215 | Q9HB40,P05023,P16435,Q969M3,Q6NUM9,O95470,Q9UBM7,O60678,P07858,O75844,P42892,P14735 | Processes and pathways | GO Biological process | msigdb_gobp | 34,509,326,403,239,143,51,244,24,185,56,467 | 244,985,185,2345,143,509,24,467,1928,326,1293,56,1554,878,525,1605,239,1531,1890,403,1499,2178,34,51 | 1.0557791765577014,0.05627090662211817,1.3148080906459898,-1.1982874368625742,1.5431638652413855,0.5455653723813071,3.316440414035143,0.6053899682620425,-0.6022778524744863,0.8552711400416021,-0.15189356987392963,2.5069145047989934,-0.32129657210781537,0.14556503368975818,0.5254338786156286,-0.34606944879987256,1.09124... | 2,468 |
Abnormality of extrapyramidal motor function | 23 | 60 | 2.450786 | 0.014254 | Q9UBB4,O14949,O96008,P17900,P11802,P16278,O75569,Q6DKK2,P07602,P06753,P04062,P12235,P08243,P98175,P35637,Q99720,Q5JPH6,Q9Y3Z3,Q9Y263,P54136,P06865,Q9Y4P3,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 258,508,267,395,153,25,277,155,28,538,49,558,186,442,561,80,82,477,366,105,232,380,388 | 508,896,2373,277,985,267,1291,49,538,232,28,1546,186,1445,153,558,25,1479,395,933,1671,989,2298,763,1295,2095,995,561,2124,105,2074,1057,1879,1773,442,788,963,1562,583,1776,82,155,1572,885,2057,2135,1434,80,1351,1257,1658,1862,388,258,1660,1864,366,477,380,2067 | 0.5455653723813071,0.12341926582388701,-1.3538973144414643,0.9839576617525956,0.05627090662211817,1.002027140929854,-0.15189356987392963,2.644481441197411,0.5052058365472561,1.1088603313127976,3.198719452250958,-0.32129657210781537,1.3148080906459898,-0.24785041714148484,1.4952459017765753,0.4848802844441598,3.27399634... | 2,468 |
Sphingolipid pathway | 6 | 8 | 2.449542 | 0.014304 | Q06136,Q16739,Q96G23,Q13510,P04062,O95470 | Processes and pathways | WikiPathways | msigdb_wp | 97,72,78,112,49,143 | 223,143,49,2049,97,112,72,78 | 1.1264079353050018,1.5431638652413855,2.644481441197411,-0.7093648604789845,1.9229529370253255,1.7750387384721054,2.312020878410862,2.1633192386683975 | 2,468 |
Lipid biosynthesis | 16 | 45 | 2.44916 | 0.014319 | Q16850,Q9NZ01,O76062,Q9NPH2,Q16739,Q96G23,Q15392,Q9UBM7,Q15800,Q9P035,O15121,P35790,Q96N66,O95864,O00116,Q14739 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 121,70,102,168,72,78,47,51,114,214,86,119,316,245,123,63 | 123,2453,1052,2320,86,102,245,1798,2429,496,119,1296,1197,594,1129,1772,1098,383,1680,2420,1884,63,2370,659,47,2437,114,72,121,1605,1309,315,1392,1577,78,316,2238,2136,889,870,168,70,214,51,1219 | 1.6837858907333896,-2.6900423224636016,0.0108995245257502,-1.137659851909859,2.023552801349019,1.8643955467119475,1.0557791765577014,-0.49788927155059765,-1.968994138846055,0.565601265268559,1.7144193117266193,-0.15189356987392963,-0.08134699713241711,0.4439327299123976,-0.03496930883195915,-0.4721974863524341,-0.01197... | 2,468 |
Abnormal bone structure | 23 | 139 | 2.44415 | 0.014519 | Q15437,Q5H8A4,P21359,P16278,P07602,Q13126,Q15392,P04062,Q9UBM7,Q86XL3,O75844,P06280,P40763,Q9Y487,Q14739,P48735,P27635,Q14108,Q15436,Q9HC07,O75874,Q13510,O00116 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 133,139,144,25,28,35,47,49,51,54,185,187,188,62,63,66,85,87,218,234,104,112,123 | 123,349,1184,231,853,1762,827,1358,430,1619,1620,1506,2007,2421,392,185,104,761,803,700,1705,2142,49,1799,2449,2070,1959,187,783,2324,1545,28,2039,495,558,2208,1708,25,1411,933,1671,1480,144,720,1034,1154,2358,957,85,1983,2311,1674,1295,411,936,1675,1193,1633,188,592,1711,397,66,1771,878,2409,1271,1199,1378,1200,612,20... | 1.6837858907333896,0.7799438888928811,-0.08134699713241711,1.1088603313127976,0.16759443900767257,-0.4721974863524341,0.18950873816397323,-0.1995959661077008,0.6448072914475071,-0.3709907348752914,-0.3709907348752914,-0.29667029004619083,-0.6823322307636482,-1.7886042606720733,0.7032523978558017,1.3148080906459898,1.84... | 2,468 |
Carboxylic acid transport | 9 | 32 | 2.441592 | 0.014623 | Q9UBX3,Q7L0J3,Q9H2D1,P21359,Q15042,P14174,P07602,Q9Y619,Q9NZJ7 | Processes and pathways | GO Biological process | msigdb_gobp | 134,38,10,144,444,280,28,292,388 | 480,855,1731,875,1292,1800,28,1801,280,144,860,835,1842,596,810,962,881,444,1136,1347,38,1996,888,10,1724,1580,665,388,134,920,1179,292 | 0.5855424906777212,0.16759443900767257,-0.44666371637530605,0.14556503368975818,-0.15189356987392963,-0.49788927155059765,3.198719452250958,-0.49788927155059765,0.9839576617525956,1.5431638652413855,0.16759443900767257,0.18950873816397323,-0.5237411060737124,0.4439327299123976,0.21130916709284053,0.07877351189206046,0.... | 2,468 |
Abnormality of the biliary system | 19 | 88 | 2.435005 | 0.014892 | Q15437,Q5H8A4,P00374,P14174,P07602,Q15904,Q16134,P40939,P04062,Q9UBM7,Q14739,P04066,Q5JPH6,Q9UJW0,Q14108,Q96J02,Q13510,Q69YQ0,Q6PGP7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 133,139,279,280,28,290,31,33,49,51,63,189,82,215,87,228,112,241,242 | 1084,696,1475,1506,985,761,1705,279,2142,49,189,1836,1799,783,1329,28,1362,1668,495,1445,2366,2458,2208,2209,280,1982,1629,1737,651,1122,860,1295,936,1483,1675,2143,2299,302,592,33,1911,2419,1965,837,2124,878,1812,1039,1843,2167,2292,1057,2216,1773,2020,1302,1304,1063,112,87,63,1776,133,290,31,139,82,944,241,242,385,18... | -0.011972007198974987,0.3186451392955738,-0.27218882129392213,-0.29667029004619083,0.05627090662211817,0.2545732583950417,-0.4212859664531922,0.9839576617525956,-0.8192985310386937,2.644481441197411,1.281166698194264,-0.5237411060737124,-0.49788927155059765,0.2329969417200938,-0.17567657782693433,3.198719452250958,-0.1... | 2,468 |
Abnormality of femur morphology | 19 | 54 | 2.434131 | 0.014928 | Q8TD19,Q9UHX1,O75718,P16278,P07602,Q9Y619,P46109,P04062,Q7LGA3,O75844,Q9NR45,P06280,Q9Y487,Q14739,P04066,P16435,O00754,O00116,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 385,405,392,25,28,292,419,49,447,185,452,187,62,63,189,326,231,123,388 | 123,1184,231,853,1620,2007,392,185,1734,700,2142,49,189,1799,187,28,25,326,1480,1930,498,2388,419,1417,2409,1376,1337,810,1454,63,1567,1717,1069,1648,2284,447,1527,1465,2285,385,816,462,947,886,1353,452,2086,572,388,405,1662,62,1290,292 | 1.6837858907333896,-0.08134699713241711,1.1088603313127976,0.16759443900767257,-0.3709907348752914,-0.6823322307636482,0.7032523978558017,1.3148080906459898,-0.44666371637530605,0.3186451392955738,-0.8192985310386937,2.644481441197411,1.281166698194264,-0.49788927155059765,1.2980205320115141,3.198719452250958,3.2739963... | 2,468 |
Motor seizure | 24 | 86 | 2.430912 | 0.015061 | Q9UBB4,Q9UBX3,Q01105,P16278,O00429,P07602,Q9Y619,O75503,P49591,Q96F86,P04062,Q96N66,P40763,Q9NZ01,O60566,Q9HA77,P27635,Q9UPT5,Q9Y3E5,Q96C86,Q13510,P28482,Q13618,Q9NZJ7 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 258,134,145,25,152,28,292,32,287,299,49,316,188,70,430,464,85,489,368,361,112,498,372,388 | 152,1586,490,827,576,982,2308,1618,430,719,1956,32,985,49,28,1546,2261,1445,857,1764,25,1593,1629,720,85,498,1984,1448,1675,188,765,1676,1055,287,2124,2416,1199,810,788,1132,1302,145,2218,1384,744,864,1775,112,372,998,1566,1489,748,944,1821,1429,691,884,1392,1578,1312,1533,361,2286,299,2191,316,1612,2269,1213,1580,1047... | 1.4952459017765753,-0.34606944879987256,0.565601265268559,0.18950873816397323,0.4644562459753665,0.05627090662211817,-1.1076784324720763,-0.3709907348752914,0.6448072914475071,0.29739620791205207,-0.6287910407099505,3.010346969899404,0.05627090662211817,2.644481441197411,3.198719452250958,-0.32129657210781537,-0.989892... | 2,468 |
Transport of small molecules | 43 | 137 | 2.417904 | 0.01561 | Q99808,P51665,P21796,P05023,Q9UBX3,Q9BUN8,P45880,P23634,P16615,Q9C0H2,P30519,P28072,P49721,Q9UBI6,P63208,Q15904,P08183,Q8WTV0,O00231,Q70HW3,P38606,P28074,Q9Y277,P12235,P20618,Q9Y487,Q93050,O43242,P28070,Q9H0U3,Q9HD20,P04920,P53985,P40855,P02786,Q8N4V1,Q9BU23,P60900,P49720,P10644,Q8TB61,Q9UJZ1,Q9UBV2 | Processes and pathways | Reactome Pathways | msigdb_reactome | 387,511,6,509,134,274,14,396,394,20,21,268,26,551,545,290,286,36,284,40,542,42,178,558,559,62,68,575,457,335,81,209,596,592,591,352,486,501,500,495,118,519,518 | 284,1898,1794,1796,696,575,828,1730,2114,699,1901,2038,761,1979,591,209,509,1707,1590,1408,1545,286,1801,2207,1668,495,1445,558,931,1092,394,1411,1736,934,990,559,1446,2290,1765,6,396,1332,1447,1511,1929,703,1767,457,268,42,860,21,2120,835,2213,995,741,1236,936,2073,1632,542,592,2144,14,1418,500,26,511,2409,1378,596,20... | 0.9658109974394301,-0.5759332603866829,-0.49788927155059765,-0.49788927155059765,0.3186451392955738,0.4644562459753665,0.18950873816397323,-0.44666371637530605,-0.7915396678024824,0.3186451392955738,-0.5759332603866829,-0.7093648604789845,0.2545732583950417,-0.6554750699704857,0.4439327299123976,1.1786210307382605,0.54... | 2,468 |
Protease | 21 | 90 | 2.416401 | 0.015675 | Q9BYT8,P42785,Q9UIQ6,P07858,Q9HB40,Q92945,P42892,O75844,P08243,P52888,P10619,Q9H3G5,Q5JRX3,Q96FW1,O14773,P42575,P55786,Q13510,Q5BJF2,Q8TC07,Q4KMP7 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 275,17,19,24,34,181,56,185,186,58,61,65,196,220,94,236,110,112,240,250,248 | 825,1325,1794,94,826,557,325,1730,185,591,1763,24,186,61,1032,2208,956,467,497,1838,1233,876,2368,1909,763,1675,2263,236,17,56,996,1515,581,511,58,1096,1843,1420,110,2048,766,1425,563,964,1063,1775,112,965,1002,288,1004,1249,248,1946,240,196,2132,1607,790,514,1209,2175,250,1495,449,376,604,2379,181,472,485,220,624,2058... | 0.18950873816397323,-0.17567657782693433,-0.49788927155059765,1.9374688026168079,0.18950873816397323,0.4848802844441598,0.8552711400416021,-0.44666371637530605,1.3148080906459898,0.4439327299123976,-0.4721974863524341,3.316440414035143,1.3148080906459898,2.3910310244631345,0.033646699417906,-0.9037132041831669,0.078773... | 2,468 |
Skin nodule | 11 | 18 | 2.415685 | 0.015706 | P48735,Q15437,Q92990,O75874,P06280,Q13510,Q06124,P16615,P11802,P52732,P35637 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 66,133,423,104,187,112,525,394,153,371,561 | 104,187,153,394,720,1674,561,66,594,371,1275,525,112,133,423,1079,1505,1792 | 1.8496309709719285,1.2980205320115141,1.4952459017765753,0.7032523978558017,0.29739620791205207,-0.3960622793653552,0.4848802844441598,2.338517782432342,0.4439327299123976,0.7417718580072862,-0.1282453451374523,0.5254338786156286,1.7750387384721054,1.6062322929490631,0.6643789100172187,0.0108995245257502,-0.27218882129... | 2,468 |
Retrograde vesicle mediated transport golgi to endoplasmic reticulum | 11 | 20 | 2.413916 | 0.015782 | Q9P2W9,P61923,P24390,Q12981,P18085,O15258,Q8TD16,Q9Y282,Q12893,Q92538,P35606 | Processes and pathways | GO Biological process | msigdb_gobp | 129,544,3,674,436,166,661,13,618,471,411 | 1026,166,1925,436,1364,3,411,1417,960,684,1097,544,618,1133,674,661,1693,471,129,13 | 0.033646699417906,1.3977702991328884,-0.6022778524744863,0.6448072914475071,-0.1995959661077008,4.4061529638753205,0.6838603272070093,-0.22365336069552152,0.07877351189206046,0.33978721059520445,-0.011972007198974987,0.5052058365472561,0.4233087298229898,-0.03496930883195915,0.3608235263603773,0.3817551739233301,-0.396... | 2,468 |
Endoplasmic reticulum | 46 | 174 | 2.411307 | 0.015895 | Q9P2W9,O43169,Q969M3,Q9BT22,Q9BUN8,P84157,O95470,Q9NQC3,Q96KC8,O96005,P35606,Q8WUJ1,P43307,Q96CS3,P62820,Q9Y3U8,Q8N0U8,Q9HCU5,Q9UBM7,Q86XL3,Q00765,O00193,Q8NF37,Q14257,Q9H3G5,P0CG08,Q9NZ01,P51648,O95197,Q96G23,O43852,Q96GC9,P27635,Q9P035,Q96KA5,Q8IV08,O15027,O15269,O76062,P49257,Q5BJF2,Q15800,P35790,Q16850,Q03519,P6226... | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 129,5,403,140,274,272,143,149,414,159,411,161,162,425,420,456,176,312,51,54,307,184,315,191,65,432,70,441,75,78,337,473,85,214,346,92,466,223,102,111,240,114,119,121,246,256 | 184,1182,1052,466,223,5,632,337,2140,480,2114,1731,102,1958,75,2179,143,159,1798,901,1443,831,1904,1800,1545,1362,1151,432,1625,1981,1091,2210,1266,1870,784,2011,1153,990,2362,651,2358,1367,1930,85,2161,1710,2327,1155,2162,411,995,119,1809,1296,1633,1449,162,1513,1876,1196,1739,1335,1514,1634,111,809,1771,2214,2046,137... | 1.3148080906459898,-0.08134699713241711,0.0108995245257502,0.6053899682620425,1.1264079353050018,4.254918317045912,0.4025832237568715,0.8177749042593478,-0.8192985310386937,0.5855424906777212,-0.7915396678024824,-0.44666371637530605,1.8643955467119475,-0.6287910407099505,2.2315443900172007,-0.8753826232126409,1.5431638... | 2,468 |
Membrane lipid catabolic process | 6 | 11 | 2.409454 | 0.015976 | P04066,P50897,Q13510,P04062,O95470,P06280 | Processes and pathways | GO Biological process | msigdb_gobp | 189,39,112,49,143,187 | 143,49,189,187,232,1546,395,39,112,752,1726 | 1.5431638652413855,2.644481441197411,1.281166698194264,1.2980205320115141,1.1088603313127976,-0.32129657210781537,0.7032523978558017,2.8135128951122743,1.7750387384721054,0.27603929431054613,-0.4212859664531922 | 2,468 |
Protein polyubiquitination | 16 | 38 | 2.39716 | 0.016523 | Q9UJX4,Q9C0C9,Q16763,Q9UJX3,Q9UJX2,O75150,Q9Y263,P19474,P49427,P55786,Q13618,Q9UIQ6,Q5VTR2,P52888,Q96FW1,Q96J02 | Processes and pathways | GO Biological process | msigdb_gobp | 488,487,261,406,533,12,366,46,333,110,372,19,445,58,220,228 | 1440,12,1477,856,46,1154,1909,1371,1674,333,58,110,2184,1422,545,1061,2218,1686,2233,372,965,2023,865,261,445,1528,220,228,487,692,19,533,406,488,628,2111,366,648 | -0.24785041714148484,3.926954124542245,-0.27218882129392213,0.16759443900767257,2.705604207310635,-0.058093817935866696,-0.5759332603866829,-0.1995959661077008,-0.3960622793653552,0.8365644866172669,2.4300032626869146,1.7900609938314576,-0.8753826232126409,-0.22365336069552152,0.5052058365472561,0.0108995245257502,-0.9... | 2,468 |
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