term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Regulation of hormone levels
17
49
2.379836
0.01732
P40939,Q9HB40,Q16836,P17858,P05023,Q9UNH7,P16435,P62820,Q969M3,Q6NUM9,O95470,Q9UBM7,O60678,P07858,O75844,P42892,P14735
Processes and pathways
GO Biological process
msigdb_gobp
33,34,351,510,509,407,326,420,403,239,143,51,244,24,185,56,467
1833,1439,2274,925,244,985,185,2345,143,875,1706,1292,509,24,1362,467,1928,326,510,805,1293,2120,33,56,1554,878,1271,596,420,525,1244,1775,707,2129,351,1605,239,911,1531,1391,1890,403,1499,1350,1434,2178,34,51,407
-0.5237411060737124,-0.24785041714148484,-1.0190242872589113,0.10115585811536389,1.0557791765577014,0.05627090662211817,1.3148080906459898,-1.1982874368625742,1.5431638652413855,0.14556503368975818,-0.4212859664531922,-0.15189356987392963,0.5455653723813071,3.316440414035143,-0.1995959661077008,0.6053899682620425,-0.6022778524744863,0.8552711400416021,0.5455653723813071,0.21130916709284053,-0.15189356987392963,-0.7915396678024824,2.9876441146417414,2.5069145047989934,-0.32129657210781537,0.14556503368975818,-0.1282453451374523,0.4439327299123976,0.6643789100172187,0.5254338786156286,-0.10473033469147558,-0.4721974863524341,0.3186451392955738,-0.7915396678024824,0.7799438888928811,-0.34606944879987256,1.0912400876291406,0.12341926582388701,-0.29667029004619083,-0.1995959661077008,-0.5497550639890549,0.7032523978558017,-0.27218882129392213,-0.17567657782693433,-0.22365336069552152,-0.8472453003312823,2.9533677053572944,2.5949584998787207,0.7032523978558017
2,468
Organonitrogen compound catabolic process
80
285
2.375158
0.017541
Q9NUJ1,Q9H773,Q8IYS1,P51665,Q6ZXV5,Q9UNN5,O75150,Q8N511,Q9UIQ6,P30519,P07858,P16278,P49721,O75503,Q13126,Q8WTV0,P50897,P28074,Q9UHG3,P04062,P42892,P10619,Q16740,P34896,Q9UBU6,O60502,O14773,P09960,A0AVT1,P55786,Q13510,Q16850,P49366,O95470,A4D1P6,O75844,P06280,P04066,Q9NRN7,Q9UPU5,P15586,Q96J02,P24941,P06865,Q9Y5A7,Q9H270,Q99816,Q9GZP4,Q16763,Q9BUN8,P46379,P28072,O00231,Q8NF37,Q8N668,O14964,P49427,Q86UV5,Q96KB5,Q9Y263,Q96EB6,Q9NRW3,Q13618,Q9UJX3,P23634,P17900,Q9H2J4,Q96CS3,Q92990,Q8N3C0,Q5VTR2,P28070,Q9Y3Z3,Q93009,P14735,Q9UJX4,Q9UL15,P60900,P49720,Q9UBV2
Processes and pathways
GO Biological process
msigdb_gobp
517,0,514,511,528,534,12,16,19,21,24,25,26,32,35,36,39,42,44,49,56,61,67,76,90,95,94,103,109,110,112,121,138,143,174,185,187,189,197,198,207,228,224,232,253,257,264,265,261,274,269,268,284,315,314,330,333,338,363,366,362,378,372,406,396,395,427,425,423,448,445,457,477,472,467,488,507,501,500,518
109,174,2448,284,1794,94,1796,330,1403,1326,799,826,575,2226,717,924,557,2068,95,1618,2140,12,1406,1925,2114,32,874,698,699,185,2204,1958,1666,856,143,2158,1706,2245,1291,2323,2435,49,189,2309,187,232,2206,1546,24,1031,1189,1087,1668,1591,103,1906,61,1960,2209,1266,467,1764,207,25,1907,1411,395,1736,804,559,1480,651,858,1154,396,2298,224,1332,1447,1511,1929,1805,2094,2161,1710,1767,457,268,42,1984,2212,1371,21,1808,1839,835,76,836,1674,2213,2042,995,2073,2466,1675,2278,2299,1037,56,2144,996,269,1676,1876,1297,2419,1418,593,138,1055,333,500,26,2250,704,39,2123,1375,2416,511,1812,1420,1637,1200,1379,2074,110,1638,501,2184,1422,904,2229,1381,1814,1060,2313,2050,545,879,1061,2395,2218,1384,906,35,730,1064,1744,1487,1816,112,2233,2099,372,1165,965,598,2023,1002,1990,706,1004,1428,2188,865,2080,1068,1249,67,261,121,1168,2132,445,1606,1251,1821,1720,528,710,1649,1528,2189,338,547,642,514,1103,448,16,314,711,315,912,845,1495,36,603,1651,1652,1072,2379,423,570,472,1044,816,425,362,947,228,644,363,2057,2442,1970,2058,793,1281,2135,1434,2178,264,817,2085,887,1996,1283,274,1396,678,265,692,257,1724,427,0,1175,1614,197,378,517,1726,1863,1505,949,1541,90,518,1895,44,19,533,406,488,1220,507,758,628,2111,759,1699,534,629,198,1864,366,477,648,253,1083,1897,2112,1793
1.7900609938314576,1.3481865209735655,-2.4782507088829866,0.9658109974394301,-0.49788927155059765,1.9374688026168079,-0.49788927155059765,0.8365644866172669,-0.22365336069552152,-0.17567657782693433,0.21130916709284053,0.18950873816397323,0.4644562459753665,-0.9322398063664452,0.29739620791205207,0.10115585811536389,0.4848802844441598,-0.7365753446833382,1.9374688026168079,-0.3709907348752914,-0.8192985310386937,3.926954124542245,-0.22365336069552152,-0.6022778524744863,-0.7915396678024824,3.010346969899404,0.14556503368975818,0.3186451392955738,0.3186451392955738,1.3148080906459898,-0.9037132041831669,-0.6287910407099505,-0.3960622793653552,0.16759443900767257,1.5431638652413855,-0.8472453003312823,-0.4212859664531922,-0.9609652532252494,-0.15189356987392963,-1.137659851909859,-2.119318322676024,2.644481441197411,1.281166698194264,-1.1076784324720763,1.2980205320115141,1.1088603313127976,-0.9037132041831669,-0.32129657210781537,3.316440414035143,0.033646699417906,-0.08134699713241711,-0.011972007198974987,-0.3960622793653552,-0.34606944879987256,1.8643955467119475,-0.5759332603866829,2.3910310244631345,-0.6287910407099505,-0.9037132041831669,-0.1282453451374523,0.6053899682620425,-0.4721974863524341,1.1958841586688884,3.273996348775714,-0.5759332603866829,-0.22365336069552152,0.7032523978558017,-0.44666371637530605,0.21130916709284053,0.4848802844441598,-0.27218882129392213,0.3817551739233301,0.16759443900767257,-0.058093817935866696,0.7032523978558017,-1.0779141700680717,1.1264079353050018,-0.17567657782693433,-0.24785041714148484,-0.29667029004619083,-0.6022778524744863,-0.49788927155059765,-0.7639661184612422,-0.8472453003312823,-0.4212859664531922,-0.4721974863524341,0.6251446041977697,1.002027140929854,2.741870933531249,-0.6554750699704857,-0.9037132041831669,-0.1995959661077008,3.368926559380632,-0.49788927155059765,-0.5237411060737124,0.18950873816397323,2.217985101813405,0.18950873816397323,-0.3960622793653552,-0.9037132041831669,-0.7093648604789845,0.05627090662211817,-0.7365753446833382,-10.28916162859888,-0.3960622793653552,-1.0190242872589113,-1.0779141700680717,0.033646699417906,2.5069145047989934,-0.8192985310386937,0.05627090662211817,1.002027140929854,-0.3960622793653552,-0.5497550639890549,-0.15189356987392963,-1.7534682900989214,-0.22365336069552152,0.4439327299123976,1.5748140446524133,0.0108995245257502,0.8365644866172669,0.565601265268559,3.252619812053995,-0.9609652532252494,0.3186451392955738,2.8135128951122743,-0.7915396678024824,-0.1995959661077008,-1.6840940352377014,0.5455653723813071,-0.49788927155059765,-0.22365336069552152,-0.3709907348752914,-0.08134699713241711,-0.1995959661077008,-0.7365753446833382,1.7900609938314576,-0.3709907348752914,0.565601265268559,-0.8753826232126409,-0.22365336069552152,0.12341926582388701,-0.9322398063664452,-0.1995959661077008,-0.49788927155059765,0.0108995245257502,-1.1076784324720763,-0.7093648604789845,0.5052058365472561,0.14556503368975818,0.0108995245257502,-1.5156579856510553,-0.9037132041831669,-0.1995959661077008,0.12341926582388701,2.9072444151690418,0.29739620791205207,0.0108995245257502,-0.44666371637530605,-0.27218882129392213,-0.49788927155059765,1.7750387384721054,-0.9322398063664452,-0.7639661184612422,0.7417718580072862,-0.058093817935866696,0.07877351189206046,0.4439327299123976,-0.6823322307636482,0.05627090662211817,-0.6554750699704857,0.3186451392955738,0.05627090662211817,-0.22365336069552152,-0.8753826232126409,0.16759443900767257,-0.7365753446833382,0.0108995245257502,-0.10473033469147558,2.338517782432342,1.0200201103056432,1.6991299075669488,-0.058093817935866696,-0.7915396678024824,0.6448072914475071,-0.34606944879987256,-0.10473033469147558,-0.49788927155059765,-0.4212859664531922,0.5254338786156286,0.3186451392955738,-0.3709907348752914,-0.29667029004619083,-0.8753826232126409,0.8177749042593478,0.5052058365472561,0.4025832237568715,0.5455653723813071,-0.011972007198974987,0.6448072914475071,3.661615789484984,0.8924386609086673,0.3186451392955738,0.8924386609086673,0.12341926582388701,0.18950873816397323,-0.27218882129392213,2.8839991952794084,0.4439327299123976,-0.3709907348752914,-0.3709907348752914,0.0108995245257502,-1.3857415258895907,0.6643789100172187,0.4848802844441598,0.6053899682620425,0.033646699417906,0.21130916709284053,0.6643789100172187,0.7609008970028596,0.10115585811536389,1.1264079353050018,0.4025832237568715,0.7609008970028596,-0.7093648604789845,-2.2752985103774694,-0.6287910407099505,-0.7093648604789845,0.2329969417200938,-0.1282453451374523,-0.7915396678024824,-0.22365336069552152,-0.8472453003312823,1.0200201103056432,0.21130916709284053,-0.7365753446833382,0.14556503368975818,-0.6554750699704857,-0.1282453451374523,1.002027140929854,-0.1995959661077008,0.3608235263603773,1.0200201103056432,0.33978721059520445,1.0379372362963877,-0.4212859664531922,0.6643789100172187,5.079978498011814,-0.058093817935866696,-0.34606944879987256,1.2472580264373727,0.7417718580072862,0.5455653723813071,-0.4212859664531922,-0.5237411060737124,-0.27218882129392213,0.10115585811536389,-0.29667029004619083,1.9807254988103864,0.5455653723813071,-0.5497550639890549,2.729815482669204,3.542845976168228,0.5254338786156286,0.7032523978558017,0.5855424906777212,-0.08134699713241711,0.565601265268559,0.27603929431054613,0.4233087298229898,-0.7639661184612422,0.27603929431054613,-0.3960622793653552,0.5254338786156286,0.4233087298229898,1.2472580264373727,-0.5237411060737124,0.7609008970028596,0.6053899682620425,0.4025832237568715,1.0557791765577014,0.0108995245257502,-0.5497550639890549,-0.7639661184612422,-0.4721974863524341
2,468
Azurophil granule lumen
11
34
2.374814
0.017558
P04066,Q9BTY2,O00754,P15586,P17900,Q99536,Q92820,P16278,P06280,O00584,P10619
Localization
GO Cellular component
msigdb_gocc
189,100,231,207,395,311,376,25,187,342,61
342,231,1475,1798,189,187,2206,1265,1546,61,930,207,25,395,498,1333,1811,1038,1129,1056,2074,615,1241,743,1559,1744,1566,1889,376,425,1281,311,100,921
0.7989016296808182,1.1088603313127976,-0.27218882129392213,-0.49788927155059765,1.281166698194264,1.2980205320115141,-0.9037132041831669,-0.1282453451374523,-0.32129657210781537,2.3910310244631345,0.10115585811536389,1.1958841586688884,3.273996348775714,0.7032523978558017,0.565601265268559,-0.17567657782693433,-0.49788927155059765,0.033646699417906,-0.03496930883195915,0.0108995245257502,-0.7365753446833382,0.4233087298229898,-0.10473033469147558,0.27603929431054613,-0.32129657210781537,-0.44666371637530605,-0.32129657210781537,-0.5497550639890549,0.7417718580072862,0.6643789100172187,-0.1282453451374523,0.9109010031706256,1.9083880241673503,0.12341926582388701
2,468
Hepatosplenomegaly
7
29
2.369561
0.017809
Q13510,P04062,P16278,P40763,P10619,Q96J02,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
112,49,25,188,61,228,63
798,231,49,1799,1546,61,1445,25,1154,2161,1414,188,1911,1711,2419,837,2409,1057,112,1716,63,1852,1012,947,228,920,922,477,1290
0.21130916709284053,1.1088603313127976,2.644481441197411,-0.49788927155059765,-0.32129657210781537,2.3910310244631345,-0.24785041714148484,3.273996348775714,-0.058093817935866696,-0.8472453003312823,-0.22365336069552152,1.2980205320115141,-0.5759332603866829,-0.4212859664531922,-1.7534682900989214,0.18950873816397323,-1.615882187826786,0.0108995245257502,1.7750387384721054,-0.4212859664531922,2.364853829476893,-0.5237411060737124,0.05627090662211817,0.10115585811536389,1.1264079353050018,0.12341926582388701,0.12341926582388701,0.6053899682620425,-0.1282453451374523
2,468
Sterol metabolism
6
23
2.365557
0.018003
O76062,Q15392,P04062,Q9UBM7,Q15800,Q14739
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
102,47,49,51,114,63
696,2114,102,1798,49,496,1838,995,1296,1772,383,1339,1680,1884,63,2370,47,2437,114,121,51,775,1219
0.3186451392955738,-0.7915396678024824,1.8643955467119475,-0.49788927155059765,2.644481441197411,0.565601265268559,-0.5237411060737124,0.05627090662211817,-0.15189356987392963,-0.4721974863524341,0.7225559645801342,-0.17567657782693433,-0.3960622793653552,-0.5497550639890549,2.364853829476893,-1.322298943353699,2.705604207310635,-2.15778072649351,1.7448358781713682,1.6991299075669488,2.5949584998787207,0.2545732583950417,-0.08134699713241711
2,468
Protein targeting to mitochondrion
8
37
2.36212
0.018171
Q9H270,Q99595,Q5JRX3,P55786,P49257,O96008,Q8N4H5,Q9NS69
Processes and pathways
GO Biological process
msigdb_gobp
257,4,196,110,111,267,177,57
349,555,266,854,1730,1507,1361,856,700,267,1031,2399,804,1293,1268,111,2250,1375,110,1061,1063,731,1490,636,1389,196,1528,177,2135,4,257,1216,1860,57,919,1116,797
0.7799438888928811,0.4848802844441598,1.002027140929854,0.16759443900767257,-0.44666371637530605,-0.29667029004619083,-0.1995959661077008,0.16759443900767257,0.3186451392955738,1.002027140929854,0.033646699417906,-1.5487932064905703,0.21130916709284053,-0.15189356987392963,-0.1282453451374523,1.7750387384721054,-0.9609652532252494,-0.1995959661077008,1.7900609938314576,0.0108995245257502,0.0108995245257502,0.29739620791205207,-0.27218882129392213,0.4025832237568715,-0.1995959661077008,1.2472580264373727,-0.29667029004619083,1.3481865209735655,-0.7915396678024824,4.271977121506668,1.0379372362963877,-0.08134699713241711,-0.5237411060737124,2.4686289872263387,0.12341926582388701,-0.011972007198974987,0.2329969417200938
2,468
Liposaccharide metabolic process
7
15
2.359108
0.018319
P04066,Q16739,Q5H8A4,P04062,Q99805,P16278,P06280
Processes and pathways
GO Biological process
msigdb_gobp
189,72,139,49,182,25,187
49,189,187,232,1546,25,395,72,139,2315,449,1312,1892,182,756
2.644481441197411,1.281166698194264,1.2980205320115141,1.1088603313127976,-0.32129657210781537,3.273996348775714,0.7032523978558017,2.312020878410862,1.5748140446524133,-1.1076784324720763,0.6448072914475071,-0.15189356987392963,-0.5497550639890549,1.3315299103873544,0.27603929431054613
2,468
Generalized myoclonic seizure
12
32
2.342804
0.019139
Q96N66,O60566,Q9Y3E5,Q01105,Q13510,P04062,P40763,P16278,O00429,P07602,Q9Y619,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
316,430,368,145,112,49,188,25,152,28,292,388
152,827,430,49,28,1445,25,720,1448,188,765,1055,2124,2416,1199,1132,145,1384,864,112,1566,1489,1312,2286,2191,316,1580,464,388,368,2067,292
1.4952459017765753,0.18950873816397323,0.6448072914475071,2.644481441197411,3.198719452250958,-0.24785041714148484,3.273996348775714,0.29739620791205207,-0.24785041714148484,1.2980205320115141,0.2545732583950417,0.0108995245257502,-0.7915396678024824,-1.6840940352377014,-0.08134699713241711,-0.03496930883195915,1.5431638652413855,-0.1995959661077008,0.16759443900767257,1.7750387384721054,-0.32129657210781537,-0.27218882129392213,-0.15189356987392963,-1.0190242872589113,-0.8753826232126409,0.8924386609086673,-0.32129657210781537,0.6251446041977697,0.7225559645801342,0.7609008970028596,-0.7093648604789845,0.9658109974394301
2,468
Innate immune system
40
238
2.341631
0.0192
P42785,P28072,P30519,Q9UQB8,P14174,P07858,P16278,P49721,P07602,O00231,Q7L576,P28074,Q07065,P19474,Q99536,P06280,Q8NF37,P10619,Q9Y487,P04066,P12956,Q93050,P49427,P15586,Q9H0U3,Q92542,O15121,Q8IV08,O00584,Q96J02,Q9BTY2,O15143,P09960,O75874,O00754,P42575,Q14974,Q14185,Q13510,P09429
Processes and pathways
Reactome Pathways
msigdb_reactome
17,268,21,22,280,24,25,26,28,284,298,42,295,46,311,187,315,61,62,189,321,68,333,207,335,339,86,92,342,228,100,101,103,104,231,236,238,237,112,357
1584,1833,284,1898,1182,1794,1440,342,231,853,1796,86,631,101,1027,2338,1762,575,1475,873,1587,760,896,985,699,104,1507,2038,1798,2245,189,1836,782,900,187,783,1329,2206,1763,1265,28,1546,2071,24,1031,1189,357,1668,103,1624,1906,494,418,61,1960,930,1669,433,1032,321,1190,1478,956,280,2210,1735,1266,1628,207,2040,25,1411,510,395,1736,1871,1837,2211,46,1364,559,1446,2290,762,2118,1332,1447,1511,1929,703,1123,1767,457,268,42,498,1333,580,681,21,1672,1674,541,1035,2073,2143,2291,542,1633,1156,236,17,2144,1416,1095,1418,333,500,26,1157,1811,1677,1038,1713,2123,1484,511,1376,1377,1129,1272,1056,1379,2074,1987,501,2125,1878,2168,1844,2184,1422,1641,2076,615,1642,904,1058,1557,1381,1814,1060,938,1558,2019,616,545,1241,1426,743,482,1559,841,525,906,295,2078,2149,1307,1684,1064,1744,1564,1816,112,2233,998,1885,966,237,1566,598,941,238,1990,706,1777,1004,1388,1168,599,2171,298,1528,1430,92,2027,1889,315,970,1784,339,376,68,425,623,1393,228,2191,793,1281,311,1109,817,625,2340,100,1317,974,335,1284,1048,1830,388,1438,738,1698,693,758,1699,921,22,1865,1148,1321,62,1760,1264
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2,468
Copii coated er to golgi transport vesicle
11
27
2.340707
0.019247
Q15363,Q15437,Q08379,P10321,Q969M3,Q9Y282,Q9Y3B3,P49257,Q15436,O15027,Q9Y3Q3
Localization
GO Cellular component
msigdb_gocc
384,133,483,418,403,13,206,111,218,466,356
490,466,1476,1956,1925,1228,900,418,111,684,1039,483,1133,730,384,218,133,1606,403,973,917,2154,2065,13,1223,206,356
0.565601265268559,0.6053899682620425,-0.27218882129392213,-0.6287910407099505,-0.6022778524744863,-0.10473033469147558,0.12341926582388701,0.6643789100172187,1.7750387384721054,0.33978721059520445,0.033646699417906,0.5855424906777212,-0.03496930883195915,0.29739620791205207,0.7225559645801342,1.1438835156965523,1.6062322929490631,-0.34606944879987256,0.7032523978558017,0.07877351189206046,0.12341926582388701,-0.8192985310386937,-0.7093648604789845,3.86209245977065,-0.08134699713241711,1.2130776498207292,0.7799438888928811
2,468
Cherry red spot of the macula
6
9
2.338112
0.019381
P06865,Q13510,P16278,P07602,P10619,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
232,112,25,28,61,388
232,28,1546,61,1152,25,395,112,388
1.1088603313127976,3.198719452250958,-0.32129657210781537,2.3910310244631345,-0.058093817935866696,3.273996348775714,0.7032523978558017,1.7750387384721054,0.7225559645801342
2,468
Cholesterol metabolism
6
22
2.332606
0.019669
O76062,Q15392,P04062,Q9UBM7,Q15800,Q14739
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
102,47,49,51,114,63
696,2114,102,1798,49,496,1838,995,1296,1772,383,1339,1680,1884,63,2370,47,2437,114,121,51,775
0.3186451392955738,-0.7915396678024824,1.8643955467119475,-0.49788927155059765,2.644481441197411,0.565601265268559,-0.5237411060737124,0.05627090662211817,-0.15189356987392963,-0.4721974863524341,0.7225559645801342,-0.17567657782693433,-0.3960622793653552,-0.5497550639890549,2.364853829476893,-1.322298943353699,2.705604207310635,-2.15778072649351,1.7448358781713682,1.6991299075669488,2.5949584998787207,0.2545732583950417
2,468
Glycosaminoglycan metabolism
6
10
2.331775
0.019713
O43505,P06865,P15586,Q8NCH0,Q8TB61,P16278
Processes and pathways
Reactome Pathways
msigdb_reactome
409,232,207,115,118,25
409,232,1546,207,25,1200,447,115,118,1113
0.6838603272070093,1.1088603313127976,-0.32129657210781537,1.1958841586688884,3.273996348775714,-0.08134699713241711,0.6448072914475071,1.7448358781713682,1.7296545033561892,-0.011972007198974987
2,468
Protein targeting
19
89
2.330396
0.019785
Q9H270,Q99595,O96008,P46379,O14925,P43307,Q8N4H5,Q9NS69,Q9Y5M8,Q5JRX3,Q00535,Q9Y2T2,O14964,Q15629,Q16543,Q14108,P55786,P49257,O60725
Processes and pathways
GO Biological process
msigdb_gobp
257,4,267,269,266,162,177,57,195,196,328,336,330,79,211,87,110,111,113
1584,349,798,1586,555,266,330,854,1475,924,113,1506,1730,1187,1507,1361,856,700,267,1031,1508,493,2399,1960,804,703,579,1806,1293,1294,722,1268,2291,592,162,269,111,654,2250,2123,1375,110,2075,1638,1454,2348,1423,1161,2050,1424,1061,328,1063,546,87,512,881,731,79,1490,211,636,1389,196,710,2235,460,1528,177,2294,916,2135,1109,4,257,1216,1860,57,919,715,476,1113,1976,759,336,1116,1023,797,195
-0.34606944879987256,0.7799438888928811,0.21130916709284053,-0.34606944879987256,0.4848802844441598,1.002027140929854,0.8365644866172669,0.16759443900767257,-0.27218882129392213,0.10115585811536389,1.759963827525142,-0.29667029004619083,-0.44666371637530605,-0.08134699713241711,-0.29667029004619083,-0.1995959661077008,0.16759443900767257,0.3186451392955738,1.002027140929854,0.033646699417906,-0.29667029004619083,0.565601265268559,-1.5487932064905703,-0.6287910407099505,0.21130916709284053,0.3186451392955738,0.4644562459753665,-0.49788927155059765,-0.15189356987392963,-0.15189356987392963,0.29739620791205207,-0.1282453451374523,-1.0483638394041492,0.4439327299123976,1.4141712431371034,1.002027140929854,1.7750387384721054,0.3817551739233301,-0.9609652532252494,-0.7915396678024824,-0.1995959661077008,1.7900609938314576,-0.7365753446833382,-0.3709907348752914,-0.24785041714148484,-1.1982874368625742,-0.22365336069552152,-0.058093817935866696,-0.7093648604789845,-0.22365336069552152,0.0108995245257502,0.8552711400416021,0.0108995245257502,0.5052058365472561,2.0093242006690732,0.5455653723813071,0.14556503368975818,0.29739620791205207,2.1495441875593015,-0.27218882129392213,1.1786210307382605,0.4025832237568715,-0.1995959661077008,1.2472580264373727,0.3186451392955738,-0.9322398063664452,0.6251446041977697,-0.29667029004619083,1.3481865209735655,-1.0483638394041492,0.12341926582388701,-0.7915396678024824,-0.011972007198974987,4.271977121506668,1.0379372362963877,-0.08134699713241711,-0.5237411060737124,2.4686289872263387,0.12341926582388701,0.3186451392955738,0.6053899682620425,-0.011972007198974987,-0.6287910407099505,0.27603929431054613,0.8365644866172669,-0.011972007198974987,0.05627090662211817,0.2329969417200938,1.2642460462437752
2,468
Phospholipid binding
19
67
2.327925
0.019916
P21796,Q9UNH7,P45880,P21359,P07602,Q8WTV0,P50897,Q9BZF1,Q92643,Q9H6U6,Q8N668,O14964,Q7Z3T8,Q14108,Q92538,O14773,P37198,P09429,Q9NZJ7
Functions
GO Molecular function
msigdb_gomf
6,407,14,144,28,36,39,172,449,318,314,330,460,87,471,94,499,357,388
94,330,778,799,717,1441,779,2068,780,760,1292,2206,28,1444,2180,357,954,1960,2366,1232,144,6,805,1481,560,499,14,1126,1416,960,39,742,1678,1598,1302,907,1989,87,1067,2024,1777,1718,460,568,884,314,711,36,471,449,1610,817,1579,1997,172,1016,756,318,388,2000,519,1220,647,407,2066,2440,2112
1.9374688026168079,0.8365644866172669,0.2329969417200938,0.21130916709284053,0.29739620791205207,-0.24785041714148484,0.2329969417200938,-0.7365753446833382,0.2329969417200938,0.2545732583950417,-0.15189356987392963,-0.9037132041831669,3.198719452250958,-0.24785041714148484,-0.8753826232126409,0.7609008970028596,0.07877351189206046,-0.6287910407099505,-1.322298943353699,-0.10473033469147558,1.5431638652413855,4.254918317045912,0.21130916709284053,-0.27218882129392213,0.4848802844441598,0.565601265268559,3.796269049554577,-0.03496930883195915,-0.22365336069552152,0.07877351189206046,2.8135128951122743,0.27603929431054613,-0.3960622793653552,-0.34606944879987256,-0.15189356987392963,0.12341926582388701,-0.6554750699704857,2.0093242006690732,0.0108995245257502,-0.6823322307636482,-0.4721974863524341,-0.4212859664531922,0.6251446041977697,0.4848802844441598,0.14556503368975818,0.8924386609086673,0.3186451392955738,2.8839991952794084,0.6053899682620425,0.6448072914475071,-0.34606944879987256,0.21130916709284053,-0.32129657210781537,-0.6554750699704857,1.38130620151236,0.05627090662211817,0.27603929431054613,0.8924386609086673,0.7225559645801342,-0.6554750699704857,0.5455653723813071,-0.08134699713241711,0.4025832237568715,0.7032523978558017,-0.7093648604789845,-2.235771034953379,-0.7639661184612422
2,468
Neutrophil degranulation
32
150
2.325609
0.020039
P42785,P17900,P30519,P14174,P07858,P16278,P07602,O00231,Q7L576,Q96CS3,Q07065,Q99536,P06280,Q8NF37,P10619,P04066,P12956,Q93050,P15586,Q9H0U3,Q92542,O15121,O00584,Q9BTY2,P09960,O75874,O00754,Q14974,Q13510,P09429,Q92820,Q9NZJ7
Processes and pathways
Reactome Pathways
msigdb_reactome
17,395,21,280,24,25,28,284,298,425,295,311,187,315,61,189,321,68,207,335,339,86,342,100,103,104,231,238,112,357,376,388
1833,284,1898,1182,1794,1440,342,231,86,631,575,1475,1587,760,896,985,104,2038,1798,2245,189,1836,782,900,187,783,1329,2206,1763,1265,28,1546,2071,24,1031,1189,357,103,1624,1906,494,418,61,1960,930,1669,433,1032,321,1190,1478,956,280,1735,1628,207,2040,25,510,395,1736,1871,1837,1364,559,762,1447,703,1767,498,1333,21,1672,541,2073,2143,2291,1633,1156,17,1416,1811,1038,1713,2123,511,1129,1272,1056,2074,1878,2168,1641,615,1642,1557,2019,616,1241,1426,743,1559,295,2149,1307,1064,1744,1564,1816,112,998,1885,966,1566,238,706,1388,1168,599,2171,298,1528,1430,2027,1889,315,970,339,376,68,425,1393,2191,793,1281,311,817,2340,100,1317,974,335,1048,388,1438,1698,1699,921,1321,1264
-0.5237411060737124,0.9658109974394301,-0.5759332603866829,-0.08134699713241711,-0.49788927155059765,-0.24785041714148484,0.7989016296808182,1.1088603313127976,2.023552801349019,0.4025832237568715,0.4644562459753665,-0.27218882129392213,-0.34606944879987256,0.2545732583950417,0.12341926582388701,0.05627090662211817,1.8496309709719285,-0.7093648604789845,-0.49788927155059765,-0.9609652532252494,1.281166698194264,-0.5237411060737124,0.2329969417200938,0.12341926582388701,1.2980205320115141,0.2329969417200938,-0.17567657782693433,-0.9037132041831669,-0.4721974863524341,-0.1282453451374523,3.198719452250958,-0.32129657210781537,-0.7365753446833382,3.316440414035143,0.033646699417906,-0.08134699713241711,0.7609008970028596,1.8643955467119475,-0.3709907348752914,-0.5759332603866829,0.565601265268559,0.6643789100172187,2.3910310244631345,-0.6287910407099505,0.10115585811536389,-0.3960622793653552,0.6448072914475071,0.033646699417906,0.8738956173150244,-0.08134699713241711,-0.27218882129392213,0.07877351189206046,0.9839576617525956,-0.44666371637530605,-0.3709907348752914,1.1958841586688884,-0.7093648604789845,3.273996348775714,0.5455653723813071,0.7032523978558017,-0.44666371637530605,-0.5497550639890549,-0.5237411060737124,-0.1995959661077008,0.4848802844441598,0.2545732583950417,-0.24785041714148484,0.3186451392955738,-0.4721974863524341,0.565601265268559,-0.17567657782693433,3.368926559380632,-0.3960622793653552,0.5052058365472561,-0.7365753446833382,-0.8192985310386937,-1.0483638394041492,-0.3709907348752914,-0.058093817935866696,3.5827914390839197,-0.22365336069552152,-0.49788927155059765,0.033646699417906,-0.4212859664531922,-0.7915396678024824,0.5455653723813071,-0.03496930883195915,-0.1282453451374523,0.0108995245257502,-0.7365753446833382,-0.5497550639890549,-0.8472453003312823,-0.3709907348752914,0.4233087298229898,-0.3709907348752914,-0.32129657210781537,-0.6823322307636482,0.4233087298229898,-0.10473033469147558,-0.22365336069552152,0.27603929431054613,-0.32129657210781537,0.9475864635773026,-0.8192985310386937,-0.15189356987392963,0.0108995245257502,-0.44666371637530605,-0.32129657210781537,-0.49788927155059765,1.7750387384721054,0.05627090662211817,-0.5497550639890549,0.07877351189206046,-0.32129657210781537,1.0912400876291406,0.3186451392955738,-0.1995959661077008,-0.058093817935866696,0.4439327299123976,-0.8472453003312823,0.9475864635773026,-0.29667029004619083,-0.22365336069552152,-0.6823322307636482,-0.5497550639890549,0.8924386609086673,0.07877351189206046,0.8177749042593478,0.7417718580072862,2.338517782432342,0.6643789100172187,-0.1995959661077008,-0.8753826232126409,0.2329969417200938,-0.1282453451374523,0.9109010031706256,0.21130916709284053,-1.167861727972861,1.9083880241673503,-0.15189356987392963,0.07877351189206046,0.8365644866172669,0.033646699417906,0.7225559645801342,-0.22365336069552152,-0.3960622793653552,-0.3960622793653552,0.12341926582388701,-0.15189356987392963,-0.10473033469147558
2,468
Mitochondrial carrier domain superfamily [IPR023395]
9
20
2.324797
0.020083
Q9UBX3,Q70HW3,Q9H2D1,O43772,P12235,Q9Y6C9,Q9HC21,Q9Y619,Q9NZJ7
Sequence
InterPro Superfamily
interpro_homologous_superfamily
134,40,10,77,558,554,515,292,388
77,556,855,1590,558,931,1842,1163,962,1526,40,1996,10,1580,515,388,134,920,292,554
2.1907384712256417,0.4848802844441598,0.16759443900767257,-0.34606944879987256,0.4848802844441598,0.10115585811536389,-0.5237411060737124,-0.058093817935866696,0.07877351189206046,-0.29667029004619083,2.7897625739952723,-0.6554750699704857,4.0449565332869035,-0.32129657210781537,0.5455653723813071,0.7225559645801342,1.6062322929490631,0.12341926582388701,0.9658109974394301,0.5052058365472561
2,468
Mitochondrial substrate/solute carrier [IPR018108]
9
20
2.324797
0.020083
Q9UBX3,Q70HW3,Q9H2D1,O43772,P12235,Q9Y6C9,Q9HC21,Q9Y619,Q9NZJ7
Sequence
InterPro Repeat
interpro_repeat
134,40,10,77,558,554,515,292,388
77,556,855,1590,558,931,1842,1163,962,1526,40,1996,10,1580,515,388,134,920,292,554
2.1907384712256417,0.4848802844441598,0.16759443900767257,-0.34606944879987256,0.4848802844441598,0.10115585811536389,-0.5237411060737124,-0.058093817935866696,0.07877351189206046,-0.29667029004619083,2.7897625739952723,-0.6554750699704857,4.0449565332869035,-0.32129657210781537,0.5455653723813071,0.7225559645801342,1.6062322929490631,0.12341926582388701,0.9658109974394301,0.5052058365472561
2,468
SLC25 family of mitochondrial transporters
9
20
2.324797
0.020083
Q9UBX3,Q70HW3,Q9H2D1,O43772,P12235,Q9Y6C9,Q9HC21,Q9Y619,Q9NZJ7
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
134,40,10,77,558,554,515,292,388
77,556,855,1590,558,931,1842,1163,962,1526,40,1996,10,1580,515,388,134,920,292,554
2.1907384712256417,0.4848802844441598,0.16759443900767257,-0.34606944879987256,0.4848802844441598,0.10115585811536389,-0.5237411060737124,-0.058093817935866696,0.07877351189206046,-0.29667029004619083,2.7897625739952723,-0.6554750699704857,4.0449565332869035,-0.32129657210781537,0.5455653723813071,0.7225559645801342,1.6062322929490631,0.12341926582388701,0.9658109974394301,0.5052058365472561
2,468
Enzyme regulator activity
50
185
2.314977
0.020614
Q15334,Q02818,O43169,Q15437,Q01105,P49770,P23634,P21359,P17900,Q9NR09,P80303,P11802,O00429,O75569,P07602,Q9NR50,Q96CS3,Q15257,Q92990,A4D1P6,Q9HCU5,Q15042,Q86XL3,Q7KZI7,Q9H6U6,P10619,P61201,O00410,P18085,P14635,Q5JRX3,Q69YN2,O60343,O95684,P55010,P63151,Q16543,Q9P035,Q92538,Q15436,Q9H6Z4,Q9C0C9,Q15435,Q9Y263,Q14185,P40616,P10644,Q8TC07,Q4KMP7,Q9NZJ7
Functions
GO Molecular function
msigdb_gomf
513,130,5,133,145,270,396,144,395,150,23,153,152,277,28,428,425,297,423,174,312,444,54,446,318,61,190,319,436,434,196,201,325,203,334,459,211,214,471,218,354,487,484,366,237,358,495,250,248,388
174,1183,319,152,1794,1440,555,5,575,2274,801,325,2386,277,2204,1868,650,203,782,1292,1903,1799,2246,831,2324,2206,28,1031,1189,954,701,61,495,153,987,1190,1962,1092,434,395,436,2277,989,2362,144,1366,396,2041,1738,807,1807,1481,580,681,1294,722,1840,723,1633,358,2263,1553,1450,1876,1416,1054,937,270,1198,1811,1771,1376,1635,1420,1098,334,543,2074,1639,1239,2251,190,1679,904,1936,1160,1423,2229,2313,2050,459,616,879,1061,617,23,145,1275,841,130,906,1244,1521,656,1684,1064,1744,1816,940,237,1818,789,1847,941,1990,658,706,1135,444,297,513,484,218,133,211,248,196,1690,201,2171,446,54,1691,1103,1253,250,471,1071,1011,423,425,1498,1612,1891,1281,1434,752,1972,1213,869,487,1016,948,1353,318,354,312,666,2288,150,428,388,949,1697,214,895,950,1177,919,1113,1832,738,1698,573,758,1582,534,852,366,1051,1321,669,2440,1083,1793
1.3481865209735655,-0.08134699713241711,0.8738956173150244,1.4952459017765753,-0.49788927155059765,-0.24785041714148484,0.4848802844441598,4.254918317045912,0.4644562459753665,-1.0190242872589113,0.21130916709284053,0.8552711400416021,-1.4501835103812906,0.9839576617525956,-0.9037132041831669,-0.5497550639890549,0.3817551739233301,1.2130776498207292,0.2329969417200938,-0.15189356987392963,-0.5759332603866829,-0.49788927155059765,-0.9609652532252494,0.18950873816397323,-1.137659851909859,-0.9037132041831669,3.198719452250958,0.033646699417906,-0.08134699713241711,0.07877351189206046,0.3186451392955738,2.3910310244631345,0.565601265268559,1.4952459017765753,0.05627090662211817,-0.08134699713241711,-0.6287910407099505,-0.011972007198974987,0.6448072914475071,0.7032523978558017,0.6448072914475071,-1.0190242872589113,0.05627090662211817,-1.290942522796084,1.5431638652413855,-0.1995959661077008,0.7032523978558017,-0.7093648604789845,-0.44666371637530605,0.21130916709284053,-0.49788927155059765,-0.27218882129392213,0.4644562459753665,0.33978721059520445,-0.15189356987392963,0.29739620791205207,-0.5237411060737124,0.29739620791205207,-0.3709907348752914,0.7609008970028596,-0.9898924303408787,-0.32129657210781537,-0.24785041714148484,-0.5497550639890549,-0.22365336069552152,0.0108995245257502,0.10115585811536389,1.002027140929854,-0.08134699713241711,-0.49788927155059765,-0.4721974863524341,-0.1995959661077008,-0.3709907348752914,-0.22365336069552152,-0.011972007198974987,0.8365644866172669,0.5052058365472561,-0.7365753446833382,-0.3709907348752914,-0.10473033469147558,-0.9609652532252494,1.281166698194264,-0.3960622793653552,0.12341926582388701,-0.6022778524744863,-0.058093817935866696,-0.22365336069552152,-0.9322398063664452,-1.1076784324720763,-0.7093648604789845,0.6251446041977697,0.4233087298229898,0.14556503368975818,0.0108995245257502,0.4233087298229898,3.326987798371381,1.5431638652413855,-0.1282453451374523,0.18950873816397323,1.637422094920818,0.12341926582388701,-0.10473033469147558,-0.29667029004619083,0.3817551739233301,-0.3960622793653552,0.0108995245257502,-0.44666371637530605,-0.49788927155059765,0.10115585811536389,1.0912400876291406,-0.49788927155059765,0.2329969417200938,-0.5237411060737124,0.10115585811536389,-0.6554750699704857,0.3817551739233301,0.3186451392955738,-0.03496930883195915,0.6448072914475071,0.9475864635773026,0.5455653723813071,0.5855424906777212,1.1438835156965523,1.6062322929490631,1.1786210307382605,1.0557791765577014,1.2472580264373727,-0.3960622793653552,1.2302020821665278,-0.8472453003312823,0.6448072914475071,2.5699842709784817,-0.3960622793653552,-0.011972007198974987,-0.10473033469147558,1.0557791765577014,0.6053899682620425,0.0108995245257502,0.05627090662211817,0.6643789100172187,0.6643789100172187,-0.27218882129392213,-0.34606944879987256,-0.5497550639890549,-0.1282453451374523,-0.22365336069552152,0.27603929431054613,-0.6287910407099505,-0.08134699713241711,0.16759443900767257,0.5855424906777212,0.05627090662211817,0.10115585811536389,-0.17567657782693433,0.8924386609086673,0.7799438888928811,0.9109010031706256,0.3817551739233301,-1.0190242872589113,1.51127818869554,0.6643789100172187,0.7225559645801342,0.10115585811536389,-0.3960622793653552,1.1786210307382605,0.14556503368975818,0.10115585811536389,-0.058093817935866696,0.12341926582388701,-0.011972007198974987,-0.49788927155059765,0.29739620791205207,-0.3960622793653552,0.4848802844441598,0.27603929431054613,-0.32129657210781537,0.5254338786156286,0.18950873816397323,0.7609008970028596,0.033646699417906,-0.15189356987392963,0.3817551739233301,-2.235771034953379,0.0108995245257502,-0.4721974863524341
2,468
Metalloprotease
7
22
2.312055
0.020775
Q5JRX3,P09960,P55786,Q9UIQ6,P42892,O75844,P52888
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
196,103,110,19,56,185,58
1794,557,1730,185,829,103,2208,467,56,58,110,196,790,604,2058,275,850,2256,1614,1505,19,2067
-0.49788927155059765,0.4848802844441598,-0.44666371637530605,1.3148080906459898,0.18950873816397323,1.8643955467119475,-0.9037132041831669,0.6053899682620425,2.5069145047989934,2.4300032626869146,1.7900609938314576,1.2472580264373727,0.2329969417200938,0.4439327299123976,-0.7093648604789845,1.002027140929854,0.18950873816397323,-0.9609652532252494,-0.34606944879987256,-0.27218882129392213,3.542845976168228,-0.7093648604789845
2,468
Lipid biosynthetic process
32
109
2.307785
0.021011
Q5H8A4,O95470,P14174,P11802,Q8WTV0,Q9NPH2,Q14534,Q15392,P04062,Q9UBM7,Q99805,Q96N66,Q8NF37,Q14739,Q9NZ01,Q16739,Q96G23,Q9P035,O15121,Q06136,O15269,O76062,O75874,Q9UBF8,Q13510,Q15800,O60678,Q9NPH0,P35790,Q16850,O95864,O00116
Processes and pathways
GO Biological process
msigdb_gobp
139,143,280,153,36,168,296,47,49,51,182,316,315,63,70,72,78,214,86,97,223,102,104,106,112,114,244,251,119,121,245,123
123,2448,2453,1052,2320,86,223,244,2114,104,102,2345,143,1544,245,1798,49,1292,509,1546,2458,153,280,496,1928,2433,326,805,2182,1838,2298,860,1293,994,995,119,1296,1037,1512,1197,594,1965,1129,1772,1098,383,2264,1680,1275,97,1063,2420,112,1884,296,63,2370,659,47,1387,2437,114,72,2129,121,1605,1389,139,637,1309,969,2315,711,315,36,1392,1577,449,1312,362,78,316,1014,1892,1108,1109,2178,182,2238,1656,2467,2136,1074,889,870,756,251,168,474,1726,70,214,1438,106,51,1113,455,1219,2111
1.6837858907333896,-2.4782507088829866,-2.6900423224636016,0.0108995245257502,-1.137659851909859,2.023552801349019,1.1264079353050018,1.0557791765577014,-0.7915396678024824,1.8496309709719285,1.8643955467119475,-1.1982874368625742,1.5431638652413855,-0.32129657210781537,1.0557791765577014,-0.49788927155059765,2.644481441197411,-0.15189356987392963,0.5455653723813071,-0.32129657210781537,-3.001354480809533,1.4952459017765753,0.9839576617525956,0.565601265268559,-0.6022778524744863,-2.0434589284659013,0.8552711400416021,0.21130916709284053,-0.8753826232126409,-0.5237411060737124,-1.0779141700680717,0.16759443900767257,-0.15189356987392963,0.05627090662211817,0.05627090662211817,1.7144193117266193,-0.15189356987392963,0.033646699417906,-0.29667029004619083,-0.08134699713241711,0.4439327299123976,-0.6287910407099505,-0.03496930883195915,-0.4721974863524341,-0.011972007198974987,0.7225559645801342,-0.9898924303408787,-0.3960622793653552,-0.1282453451374523,1.9229529370253255,0.0108995245257502,-1.7534682900989214,1.7750387384721054,-0.5497550639890549,0.9475864635773026,2.364853829476893,-1.322298943353699,0.3817551739233301,2.705604207310635,-0.1995959661077008,-2.15778072649351,1.7448358781713682,2.312020878410862,-0.7915396678024824,1.6991299075669488,-0.34606944879987256,-0.1995959661077008,1.5748140446524133,0.4025832237568715,-0.15189356987392963,0.07877351189206046,-1.1076784324720763,0.3186451392955738,0.8924386609086673,2.8839991952794084,-0.1995959661077008,-0.32129657210781537,0.6448072914475071,-0.15189356987392963,0.7609008970028596,2.1633192386683975,0.8924386609086673,0.05627090662211817,-0.5497550639890549,-0.011972007198974987,-0.011972007198974987,-0.8472453003312823,1.3315299103873544,-0.9322398063664452,-0.3709907348752914,-11.679138520697085,-0.7915396678024824,0.0108995245257502,0.14556503368975818,0.16759443900767257,0.27603929431054613,1.0557791765577014,1.3977702991328884,0.6053899682620425,-0.4212859664531922,2.3252895643479303,1.1786210307382605,-0.22365336069552152,1.834815592336478,2.5949584998787207,-0.011972007198974987,0.6448072914475071,-0.08134699713241711,-0.7639661184612422
2,468
Mitochondrial transport
16
69
2.306421
0.021087
Q9H270,Q99595,Q9UBX3,Q5JRX3,Q96EK5,P23786,O43772,P45880,P55786,P49257,O96008,Q8N4H5,O14925,O75964,Q15070,Q9NS69
Processes and pathways
GO Biological process
msigdb_gobp
257,4,134,196,329,293,77,14,110,111,267,177,266,50,210,57
349,555,266,854,77,2007,1730,2115,50,1507,1361,856,700,267,1799,1590,1328,1031,1905,2399,558,804,293,670,2441,2347,1124,1293,1268,1482,1512,14,2424,2419,111,2250,704,1375,582,110,1742,1061,1063,210,731,1490,882,636,1389,196,1526,1528,1918,1278,177,329,2057,2135,4,257,1216,1860,57,919,134,920,519,1116,797
0.7799438888928811,0.4848802844441598,1.002027140929854,0.16759443900767257,2.1907384712256417,-0.6823322307636482,-0.44666371637530605,-0.7915396678024824,2.6073921114062215,-0.29667029004619083,-0.1995959661077008,0.16759443900767257,0.3186451392955738,1.002027140929854,-0.49788927155059765,-0.34606944879987256,-0.17567657782693433,0.033646699417906,-0.5759332603866829,-1.5487932064905703,0.4848802844441598,0.21130916709284053,0.9475864635773026,0.3608235263603773,-2.2752985103774694,-1.1982874368625742,-0.03496930883195915,-0.15189356987392963,-0.1282453451374523,-0.27218882129392213,-0.29667029004619083,3.796269049554577,-1.8240466439502927,-1.7534682900989214,1.7750387384721054,-0.9609652532252494,0.3186451392955738,-0.1995959661077008,0.4644562459753665,1.7900609938314576,-0.44666371637530605,0.0108995245257502,0.0108995245257502,1.1786210307382605,0.29739620791205207,-0.27218882129392213,0.14556503368975818,0.4025832237568715,-0.1995959661077008,1.2472580264373727,-0.29667029004619083,-0.29667029004619083,-0.5759332603866829,-0.1282453451374523,1.3481865209735655,0.8552711400416021,-0.7093648604789845,-0.7915396678024824,4.271977121506668,1.0379372362963877,-0.08134699713241711,-0.5237411060737124,2.4686289872263387,0.12341926582388701,1.6062322929490631,0.12341926582388701,0.5455653723813071,-0.011972007198974987,0.2329969417200938
2,468
Inorganic molecular entity transmembrane transporter activity
17
65
2.305678
0.021129
Q8N4V1,Q93050,Q9UBX3,P21796,Q00535,Q9HC07,Q13423,P45880,Q9H0U3,P23634,O75964,Q9Y277,Q9C0H2,Q9HD20,Q9UDW1,P04920,Q9Y487
Functions
GO Molecular function
msigdb_gomf
352,68,134,6,328,234,344,14,335,396,50,178,20,81,151,209,62
1700,1475,2115,50,761,2322,209,509,1707,1590,1328,2206,2180,1801,2091,432,1509,558,857,394,934,2093,1446,2290,6,396,670,2441,763,835,936,1482,542,14,2424,2409,810,1742,1058,2348,1881,1163,328,962,344,1388,910,352,1391,1044,68,1654,20,335,1724,1580,234,81,134,151,738,1081,178,1179,62
-0.4212859664531922,-0.27218882129392213,-0.7915396678024824,2.6073921114062215,0.2545732583950417,-1.137659851909859,1.1786210307382605,0.5455653723813071,-0.4212859664531922,-0.34606944879987256,-0.17567657782693433,-0.9037132041831669,-0.8753826232126409,-0.49788927155059765,-0.7639661184612422,0.6448072914475071,-0.29667029004619083,0.4848802844441598,0.16759443900767257,0.7032523978558017,0.10115585811536389,-0.7639661184612422,-0.24785041714148484,-1.0483638394041492,4.254918317045912,0.7032523978558017,0.3608235263603773,-2.2752985103774694,0.2545732583950417,0.18950873816397323,0.10115585811536389,-0.27218882129392213,0.5052058365472561,3.796269049554577,-1.8240466439502927,-1.615882187826786,0.21130916709284053,-0.44666371637530605,0.0108995245257502,-1.1982874368625742,-0.5497550639890549,-0.058093817935866696,0.8552711400416021,0.07877351189206046,0.7989016296808182,-0.1995959661077008,0.12341926582388701,0.7799438888928811,-0.1995959661077008,0.033646699417906,2.338517782432342,-0.3709907348752914,3.4207949011245122,0.8365644866172669,-0.4212859664531922,-0.32129657210781537,1.1088603313127976,2.094000982565671,1.6062322929490631,1.51127818869554,0.29739620791205207,0.0108995245257502,1.3481865209735655,-0.058093817935866696,2.3779621596515104
2,468
Lipid metabolism
25
98
2.300749
0.021406
Q9H6V9,O95470,P07602,P40939,Q9NPH2,Q15392,P11310,P04062,Q9UBM7,Q14739,Q9NZ01,Q16739,Q96G23,Q9P035,O15121,Q06136,O15269,O76062,P09960,Q13510,Q15800,Q9NPH0,P35790,Q16850,O00116
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
8,143,28,33,168,47,175,49,51,63,70,72,78,214,86,97,223,102,103,112,114,251,119,121,123
521,123,2448,2453,1052,2320,696,86,223,925,2114,698,102,143,1544,245,1798,49,2449,28,103,175,2429,496,395,1838,293,2298,2094,1333,2212,994,995,119,1296,33,1768,1512,765,1197,594,1965,2123,441,878,1129,1772,1098,383,2167,1426,1339,1680,97,503,2420,112,1884,63,400,1778,2370,659,47,2437,114,72,351,121,1605,1347,1309,844,2426,711,315,1209,1392,1577,78,316,2178,752,2238,2467,2136,889,870,8,251,168,70,214,51,775,1219,1976,872
0.5254338786156286,1.6837858907333896,-2.4782507088829866,-2.6900423224636016,0.0108995245257502,-1.137659851909859,0.3186451392955738,2.023552801349019,1.1264079353050018,0.10115585811536389,-0.7915396678024824,0.3186451392955738,1.8643955467119475,1.5431638652413855,-0.32129657210781537,1.0557791765577014,-0.49788927155059765,2.644481441197411,-2.5199026771318773,3.198719452250958,1.8643955467119475,1.3481865209735655,-1.968994138846055,0.565601265268559,0.7032523978558017,-0.5237411060737124,0.9475864635773026,-1.0779141700680717,-0.7639661184612422,-0.17567657782693433,-0.9037132041831669,0.05627090662211817,0.05627090662211817,1.7144193117266193,-0.15189356987392963,2.9876441146417414,-0.4721974863524341,-0.29667029004619083,0.2545732583950417,-0.08134699713241711,0.4439327299123976,-0.6287910407099505,-0.7915396678024824,0.6448072914475071,0.14556503368975818,-0.03496930883195915,-0.4721974863524341,-0.011972007198974987,0.7225559645801342,-0.8472453003312823,-0.22365336069552152,-0.17567657782693433,-0.3960622793653552,1.9229529370253255,0.565601265268559,-1.7534682900989214,1.7750387384721054,-0.5497550639890549,2.364853829476893,0.7032523978558017,-0.4721974863524341,-1.322298943353699,0.3817551739233301,2.705604207310635,-2.15778072649351,1.7448358781713682,2.312020878410862,0.7799438888928811,1.6991299075669488,-0.34606944879987256,-0.17567657782693433,-0.15189356987392963,0.18950873816397323,-1.859801013532104,0.3186451392955738,0.8924386609086673,-0.08134699713241711,-0.1995959661077008,-0.32129657210781537,2.1633192386683975,0.8924386609086673,-0.8472453003312823,0.27603929431054613,-0.9322398063664452,-11.679138520697085,-0.7915396678024824,0.14556503368975818,0.16759443900767257,4.186023680783169,1.0557791765577014,1.3977702991328884,2.3252895643479303,1.1786210307382605,2.5949584998787207,0.2545732583950417,-0.08134699713241711,-0.6287910407099505,0.16759443900767257
2,468
Splenomegaly
16
68
2.299703
0.021465
P04066,P50851,Q15437,O00754,Q9BT22,Q15392,P15586,P04062,Q13510,Q6PGP7,Q14108,P14174,P16278,P07602,Q96J02,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
189,225,133,231,140,47,207,49,112,242,87,280,25,28,228,63
798,231,1586,696,1619,2005,1085,803,2245,2435,2142,49,189,1836,1799,1959,1329,2324,28,494,1445,2366,1626,2458,2208,280,207,25,1629,1446,651,1365,2161,457,860,1909,764,936,1483,1414,594,225,878,2409,1039,1843,1200,2216,1063,112,87,63,47,133,687,290,242,1072,424,816,1012,947,228,140,335,1504,1505,388
0.21130916709284053,1.1088603313127976,-0.34606944879987256,0.3186451392955738,-0.3709907348752914,-0.6823322307636482,-0.011972007198974987,0.21130916709284053,-0.9609652532252494,-2.119318322676024,-0.8192985310386937,2.644481441197411,1.281166698194264,-0.5237411060737124,-0.49788927155059765,-0.6287910407099505,-0.17567657782693433,-1.137659851909859,3.198719452250958,0.565601265268559,-0.24785041714148484,-1.322298943353699,-0.3709907348752914,-3.001354480809533,-0.9037132041831669,0.9839576617525956,1.1958841586688884,3.273996348775714,-0.3709907348752914,-0.24785041714148484,0.3817551739233301,-0.1995959661077008,-0.8472453003312823,0.6251446041977697,0.16759443900767257,-0.5759332603866829,0.2545732583950417,0.10115585811536389,-0.27218882129392213,-0.22365336069552152,0.4439327299123976,1.1264079353050018,0.14556503368975818,-1.615882187826786,0.033646699417906,-0.5237411060737124,-0.08134699713241711,-0.9037132041831669,0.0108995245257502,1.7750387384721054,2.0093242006690732,2.364853829476893,2.705604207310635,1.6062322929490631,0.33978721059520445,0.9658109974394301,1.073546580138068,0.0108995245257502,0.6643789100172187,0.21130916709284053,0.05627090662211817,0.10115585811536389,1.1264079353050018,1.5748140446524133,0.8365644866172669,-0.27218882129392213,-0.27218882129392213,0.7225559645801342
2,468
Alcohol metabolic process
17
65
2.295124
0.021726
Q8WTV0,P48735,O15269,O76062,Q9NPH2,Q14534,O75874,Q6NUM9,Q15392,Q13510,P04062,Q9BQE5,Q9UBM7,Q15800,P00374,Q16850,Q14739
Processes and pathways
GO Biological process
msigdb_gobp
36,66,223,102,168,296,104,239,47,112,49,18,51,114,279,121,63
2113,696,223,2138,2114,104,102,2345,279,1798,49,986,2458,1627,496,2181,1928,326,1907,1838,1191,2095,995,1296,1512,1269,1197,66,1965,2279,1934,837,2124,441,1129,1772,383,2216,1879,1339,1680,1275,1063,112,1884,296,63,2370,47,2437,114,2129,121,239,2104,1531,1890,36,1434,2365,18,168,51,775,1261
-0.7915396678024824,0.3186451392955738,1.1264079353050018,-0.8192985310386937,-0.7915396678024824,1.8496309709719285,1.8643955467119475,-1.1982874368625742,0.9839576617525956,-0.49788927155059765,2.644481441197411,0.05627090662211817,-3.001354480809533,-0.3709907348752914,0.565601265268559,-0.8753826232126409,-0.6022778524744863,0.8552711400416021,-0.5759332603866829,-0.5237411060737124,-0.08134699713241711,-0.7639661184612422,0.05627090662211817,-0.15189356987392963,-0.29667029004619083,-0.1282453451374523,-0.08134699713241711,2.338517782432342,-0.6287910407099505,-1.0190242872589113,-0.6022778524744863,0.18950873816397323,-0.7915396678024824,0.6448072914475071,-0.03496930883195915,-0.4721974863524341,0.7225559645801342,-0.9037132041831669,-0.5497550639890549,-0.17567657782693433,-0.3960622793653552,-0.1282453451374523,0.0108995245257502,1.7750387384721054,-0.5497550639890549,0.9475864635773026,2.364853829476893,-1.322298943353699,2.705604207310635,-2.15778072649351,1.7448358781713682,-0.7915396678024824,1.6991299075669488,1.0912400876291406,-0.7639661184612422,-0.29667029004619083,-0.5497550639890549,2.8839991952794084,-0.22365336069552152,-1.290942522796084,3.5827914390839197,1.3977702991328884,2.5949584998787207,0.2545732583950417,-0.10473033469147558
2,468
Transport vesicle
28
77
2.295081
0.021729
Q15363,Q15334,P24390,Q15437,Q8TBA6,O00429,P35606,P61923,Q7L0J3,P50897,P38606,P10321,P62820,O43493,O43760,Q92572,O00461,P11717,Q9Y3B3,Q92542,Q92905,Q15436,Q86Y82,O15027,Q9Y3Q3,Q9HD26,P49257,O14653
Localization
GO Cellular component
msigdb_gocc
384,513,3,133,402,152,411,544,38,39,542,418,420,169,320,585,193,433,206,339,604,218,469,466,356,364,111,490
152,193,1026,490,466,631,1978,1703,169,2037,1900,320,926,1476,1956,1925,1228,1979,900,2207,701,418,1669,433,934,680,1364,3,1806,2183,411,542,1417,111,684,39,2123,726,1271,1272,1097,1039,1299,1878,2168,1641,1058,544,420,1132,1244,730,1989,1342,1718,513,384,218,133,707,38,469,402,339,585,604,753,973,1319,364,917,2154,2065,1113,206,356,609
1.4952459017765753,1.2642460462437752,0.033646699417906,0.565601265268559,0.6053899682620425,0.4025832237568715,-0.6554750699704857,-0.4212859664531922,1.38130620151236,-0.7093648604789845,-0.5759332603866829,0.8738956173150244,0.10115585811536389,-0.27218882129392213,-0.6287910407099505,-0.6022778524744863,-0.10473033469147558,-0.6554750699704857,0.12341926582388701,-0.9037132041831669,0.3186451392955738,0.6643789100172187,-0.3960622793653552,0.6448072914475071,0.10115585811536389,0.33978721059520445,-0.1995959661077008,4.4061529638753205,-0.49788927155059765,-0.8753826232126409,0.6838603272070093,0.5052058365472561,-0.22365336069552152,1.7750387384721054,0.33978721059520445,2.8135128951122743,-0.7915396678024824,0.29739620791205207,-0.1282453451374523,-0.1282453451374523,-0.011972007198974987,0.033646699417906,-0.15189356987392963,-0.5497550639890549,-0.8472453003312823,-0.3709907348752914,0.0108995245257502,0.5052058365472561,0.6643789100172187,-0.03496930883195915,-0.10473033469147558,0.29739620791205207,-0.6554750699704857,-0.17567657782693433,-0.4212859664531922,0.5455653723813071,0.7225559645801342,1.1438835156965523,1.6062322929490631,0.3186451392955738,2.8488980910832757,0.6053899682620425,0.7032523978558017,0.8177749042593478,0.4644562459753665,0.4439327299123976,0.27603929431054613,0.07877351189206046,-0.15189356987392963,0.7609008970028596,0.12341926582388701,-0.8192985310386937,-0.7093648604789845,-0.011972007198974987,1.2130776498207292,0.7799438888928811,0.4439327299123976
2,468
Clumsiness
7
17
2.294134
0.021783
O75503,O14773,Q69YN2,O00754,Q13510,P07602,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,94,201,231,112,28,388
231,94,853,1475,1120,32,538,28,1448,936,2218,112,400,201,1570,388,1895
1.1088603313127976,1.9374688026168079,0.16759443900767257,-0.27218882129392213,-0.03496930883195915,3.010346969899404,0.5052058365472561,3.198719452250958,-0.24785041714148484,0.10115585811536389,-0.9037132041831669,1.7750387384721054,0.7032523978558017,1.2302020821665278,-0.32129657210781537,0.7225559645801342,-0.5497550639890549
2,468
Steroid metabolic process
10
54
2.29115
0.021955
Q8WTV0,O76062,Q15392,Q13510,P04062,Q9BQE5,Q9UBM7,Q15800,Q16850,Q14739
Processes and pathways
GO Biological process
msigdb_gobp
36,102,47,112,49,18,51,114,121,63
696,2114,102,143,1798,49,509,2458,496,1928,326,805,2182,1838,2298,860,1293,995,1296,1193,1512,1197,1965,2124,878,1129,1772,383,1339,1680,1561,112,1884,296,63,2370,47,1387,2437,114,121,1605,2171,36,362,1108,2178,18,2136,870,51,775,455,1219
0.3186451392955738,-0.7915396678024824,1.8643955467119475,1.5431638652413855,-0.49788927155059765,2.644481441197411,0.5455653723813071,-3.001354480809533,0.565601265268559,-0.6022778524744863,0.8552711400416021,0.21130916709284053,-0.8753826232126409,-0.5237411060737124,-1.0779141700680717,0.16759443900767257,-0.15189356987392963,0.05627090662211817,-0.15189356987392963,-0.08134699713241711,-0.29667029004619083,-0.08134699713241711,-0.6287910407099505,-0.7915396678024824,0.14556503368975818,-0.03496930883195915,-0.4721974863524341,0.7225559645801342,-0.17567657782693433,-0.3960622793653552,-0.32129657210781537,1.7750387384721054,-0.5497550639890549,0.9475864635773026,2.364853829476893,-1.322298943353699,2.705604207310635,-0.1995959661077008,-2.15778072649351,1.7448358781713682,1.6991299075669488,-0.34606944879987256,-0.8472453003312823,2.8839991952794084,0.7609008970028596,-0.011972007198974987,-0.8472453003312823,3.5827914390839197,-0.7915396678024824,0.16759443900767257,2.5949584998787207,0.2545732583950417,0.6448072914475071,-0.08134699713241711
2,468
Organic acid transport
8
41
2.290671
0.021982
P08183,Q9UBX3,Q7L0J3,Q9H2D1,O43772,P21359,P14174,Q9Y619
Processes and pathways
GO Biological process
msigdb_gobp
286,134,38,10,77,144,280,292
77,556,480,855,1731,875,1544,2323,1292,1800,832,286,1801,1445,280,144,293,860,1370,994,835,1842,596,810,962,881,444,1136,1347,1008,38,1996,888,10,1724,1580,665,134,920,1179,292
2.1907384712256417,0.4848802844441598,0.5855424906777212,0.16759443900767257,-0.44666371637530605,0.14556503368975818,-0.32129657210781537,-1.137659851909859,-0.15189356987392963,-0.49788927155059765,0.18950873816397323,0.9658109974394301,-0.49788927155059765,-0.24785041714148484,0.9839576617525956,1.5431638652413855,0.9475864635773026,0.16759443900767257,-0.1995959661077008,0.05627090662211817,0.18950873816397323,-0.5237411060737124,0.4439327299123976,0.21130916709284053,0.07877351189206046,0.14556503368975818,0.6448072914475071,-0.03496930883195915,-0.17567657782693433,0.05627090662211817,2.8488980910832757,-0.6554750699704857,0.14556503368975818,4.0449565332869035,-0.4212859664531922,-0.32129657210781537,0.3817551739233301,1.6062322929490631,0.12341926582388701,-0.058093817935866696,0.9658109974394301
2,468
Cellular protein catabolic process
63
184
2.278727
0.022683
Q9H270,P51665,Q99816,Q9GZP4,Q6ZXV5,Q9UNN5,Q9UJX2,O75150,Q16763,Q9BUN8,Q9UJX3,Q8N511,P46379,P28072,P07858,P49721,P63208,Q8IXB1,O00231,Q9H2J4,P50897,Q96CS3,Q92990,P28074,Q9UHG3,A4D1P6,Q93008,P04062,Q8N3C0,O75844,P20618,Q5VTR2,Q8N668,Q16740,Q9UPU5,O43242,P49427,P28070,Q86UV5,Q8WUM4,Q93009,Q9UBU6,P14735,P48729,Q96J02,O14773,Q14258,Q9Y5A7,Q9UJX4,P24941,Q96KB5,Q9ULT8,Q9UNS2,Q9Y263,Q9UL15,Q96EB6,A0AVT1,P60900,P49720,Q9Y4X5,Q13618,Q96JB5,Q9UBV2
Processes and pathways
GO Biological process
msigdb_gobp
257,511,264,265,528,534,533,12,261,274,406,16,269,268,24,26,545,547,284,427,39,425,423,42,44,174,570,49,448,185,559,445,314,67,198,575,333,457,338,603,472,90,467,593,228,94,598,253,488,224,363,628,629,366,507,362,109,501,500,648,372,644,518
109,174,284,1794,94,1796,1403,799,826,575,717,924,1618,2140,12,1406,2114,699,185,2204,1958,856,49,2206,24,1031,1189,1906,1266,467,1764,1411,1736,804,559,858,1154,224,1332,1447,1511,1929,1805,2161,1710,1767,457,268,42,1371,1674,2042,2073,1675,2144,996,269,1876,2419,1418,593,333,500,26,2250,704,39,2123,1375,511,1420,1637,1379,2074,1638,501,2184,1422,904,2229,1381,1814,1060,2313,2050,545,879,1061,2218,906,1064,1744,1487,2233,2099,372,1165,598,2023,1002,1990,706,1004,1428,2188,865,1068,67,261,1168,2132,445,1606,528,710,1649,1528,2189,338,547,642,1103,448,16,314,912,845,1495,603,1651,1652,1072,2379,423,570,472,1044,816,425,362,947,228,644,363,2057,1970,2058,793,1281,2135,1434,264,1283,274,678,265,692,257,427,1863,949,1541,90,518,44,533,406,488,507,758,628,2111,759,1699,534,629,198,1864,366,648,253,1083,1897,1793
1.7900609938314576,1.3481865209735655,0.9658109974394301,-0.49788927155059765,1.9374688026168079,-0.49788927155059765,-0.22365336069552152,0.21130916709284053,0.18950873816397323,0.4644562459753665,0.29739620791205207,0.10115585811536389,-0.3709907348752914,-0.8192985310386937,3.926954124542245,-0.22365336069552152,-0.7915396678024824,0.3186451392955738,1.3148080906459898,-0.9037132041831669,-0.6287910407099505,0.16759443900767257,2.644481441197411,-0.9037132041831669,3.316440414035143,0.033646699417906,-0.08134699713241711,-0.5759332603866829,-0.1282453451374523,0.6053899682620425,-0.4721974863524341,-0.22365336069552152,-0.44666371637530605,0.21130916709284053,0.4848802844441598,0.16759443900767257,-0.058093817935866696,1.1264079353050018,-0.17567657782693433,-0.24785041714148484,-0.29667029004619083,-0.6022778524744863,-0.49788927155059765,-0.8472453003312823,-0.4212859664531922,-0.4721974863524341,0.6251446041977697,1.002027140929854,2.741870933531249,-0.1995959661077008,-0.3960622793653552,-0.7093648604789845,-0.7365753446833382,-0.3960622793653552,-0.8192985310386937,0.05627090662211817,1.002027140929854,-0.5497550639890549,-1.7534682900989214,-0.22365336069552152,0.4439327299123976,0.8365644866172669,0.565601265268559,3.252619812053995,-0.9609652532252494,0.3186451392955738,2.8135128951122743,-0.7915396678024824,-0.1995959661077008,0.5455653723813071,-0.22365336069552152,-0.3709907348752914,-0.1995959661077008,-0.7365753446833382,-0.3709907348752914,0.565601265268559,-0.8753826232126409,-0.22365336069552152,0.12341926582388701,-0.9322398063664452,-0.1995959661077008,-0.49788927155059765,0.0108995245257502,-1.1076784324720763,-0.7093648604789845,0.5052058365472561,0.14556503368975818,0.0108995245257502,-0.9037132041831669,0.12341926582388701,0.0108995245257502,-0.44666371637530605,-0.27218882129392213,-0.9322398063664452,-0.7639661184612422,0.7417718580072862,-0.058093817935866696,0.4439327299123976,-0.6823322307636482,0.05627090662211817,-0.6554750699704857,0.3186451392955738,0.05627090662211817,-0.22365336069552152,-0.8753826232126409,0.16759443900767257,0.0108995245257502,2.338517782432342,1.0200201103056432,-0.058093817935866696,-0.7915396678024824,0.6448072914475071,-0.34606944879987256,0.5254338786156286,0.3186451392955738,-0.3709907348752914,-0.29667029004619083,-0.8753826232126409,0.8177749042593478,0.5052058365472561,0.4025832237568715,-0.011972007198974987,0.6448072914475071,3.661615789484984,0.8924386609086673,0.12341926582388701,0.18950873816397323,-0.27218882129392213,0.4439327299123976,-0.3709907348752914,-0.3709907348752914,0.0108995245257502,-1.3857415258895907,0.6643789100172187,0.4848802844441598,0.6053899682620425,0.033646699417906,0.21130916709284053,0.6643789100172187,0.7609008970028596,0.10115585811536389,1.1264079353050018,0.4025832237568715,0.7609008970028596,-0.7093648604789845,-0.6287910407099505,-0.7093648604789845,0.2329969417200938,-0.1282453451374523,-0.7915396678024824,-0.22365336069552152,1.0200201103056432,-0.1282453451374523,1.002027140929854,0.3608235263603773,1.0200201103056432,0.33978721059520445,1.0379372362963877,0.6643789100172187,-0.5237411060737124,0.10115585811536389,-0.29667029004619083,1.9807254988103864,0.5455653723813071,2.729815482669204,0.5254338786156286,0.7032523978558017,0.5855424906777212,0.565601265268559,0.27603929431054613,0.4233087298229898,-0.7639661184612422,0.27603929431054613,-0.3960622793653552,0.5254338786156286,0.4233087298229898,1.2472580264373727,-0.5237411060737124,0.7609008970028596,0.4025832237568715,1.0557791765577014,0.0108995245257502,-0.5497550639890549,-0.4721974863524341
2,468
Vacuolar membrane
13
94
2.277013
0.022785
O75503,Q93050,Q8WTV0,O95772,Q8N511,P42785,P04062,Q9UIQ6,Q14108,P42892,P07602,P10619,Q9Y487
Localization
GO Cellular component
msigdb_gocc
32,68,36,41,16,17,49,19,87,56,28,61,62
798,1586,696,1978,717,2037,1225,760,896,32,985,1442,2038,41,1979,49,1443,2206,28,2180,1801,1189,1802,2207,494,61,167,1960,1669,1446,2290,858,703,722,1094,542,1633,1037,17,56,1676,1713,2123,2409,1271,1378,1641,1058,2145,524,1132,1384,295,2051,1304,87,2171,92,16,315,36,2267,339,68,1012,2286,2134,473,2057,713,817,1656,2467,974,1790,335,714,587,257,234,364,388,1438,2065,738,19,1288,759,2451,1864,336,1116,62,369
0.21130916709284053,-0.34606944879987256,0.3186451392955738,-0.6554750699704857,0.29739620791205207,-0.7093648604789845,-0.10473033469147558,0.2545732583950417,0.12341926582388701,3.010346969899404,0.05627090662211817,-0.24785041714148484,-0.7093648604789845,2.741870933531249,-0.6554750699704857,2.644481441197411,-0.24785041714148484,-0.9037132041831669,3.198719452250958,-0.8753826232126409,-0.49788927155059765,-0.08134699713241711,-0.49788927155059765,-0.9037132041831669,0.565601265268559,2.3910310244631345,1.3977702991328884,-0.6287910407099505,-0.3960622793653552,-0.24785041714148484,-1.0483638394041492,0.16759443900767257,0.3186451392955738,0.29739620791205207,-0.011972007198974987,0.5052058365472561,-0.3709907348752914,0.033646699417906,3.5827914390839197,2.5069145047989934,-0.3960622793653552,-0.4212859664531922,-0.7915396678024824,-1.615882187826786,-0.1282453451374523,-0.1995959661077008,-0.3709907348752914,0.0108995245257502,-0.8192985310386937,0.5254338786156286,-0.03496930883195915,-0.1995959661077008,0.9475864635773026,-0.7093648604789845,-0.15189356987392963,2.0093242006690732,-0.8472453003312823,1.966354748749709,3.661615789484984,0.8924386609086673,2.8839991952794084,-0.9898924303408787,0.8177749042593478,2.338517782432342,0.05627090662211817,-1.0190242872589113,-0.7915396678024824,0.6053899682620425,-0.7093648604789845,0.3186451392955738,0.21130916709284053,-0.3709907348752914,-11.679138520697085,0.07877351189206046,-0.4721974863524341,0.8365644866172669,0.3186451392955738,0.4644562459753665,1.0379372362963877,1.1088603313127976,0.7609008970028596,0.7225559645801342,-0.22365336069552152,-0.7093648604789845,0.29739620791205207,3.542845976168228,-0.1282453451374523,0.27603929431054613,-2.5199026771318773,-0.5237411060737124,0.8365644866172669,-0.011972007198974987,2.3779621596515104,0.7609008970028596
2,468
Abnormality of the gingiva
8
39
2.276996
0.022786
Q15392,P49257,P04062,Q9UBM7,Q14108,P16278,P40763,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
47,111,49,51,87,25,188,63
798,231,1619,803,49,2324,495,2040,25,2415,1446,1295,188,1126,111,1454,1773,1275,905,864,1203,87,63,2024,1776,47,2025,621,2293,1608,570,1892,678,1504,51,1660,1081,1662,380
0.21130916709284053,1.1088603313127976,-0.3709907348752914,0.21130916709284053,2.644481441197411,-1.137659851909859,0.565601265268559,-0.7093648604789845,3.273996348775714,-1.6840940352377014,-0.24785041714148484,-0.15189356987392963,1.2980205320115141,-0.03496930883195915,1.7750387384721054,-0.24785041714148484,-0.4721974863524341,-0.1282453451374523,0.12341926582388701,0.16759443900767257,-0.08134699713241711,2.0093242006690732,2.364853829476893,-0.6823322307636482,-0.4721974863524341,2.705604207310635,-0.6823322307636482,0.4233087298229898,-1.0483638394041492,-0.34606944879987256,0.4848802844441598,-0.5497550639890549,0.3608235263603773,-0.27218882129392213,2.5949584998787207,-0.3709907348752914,0.0108995245257502,-0.3709907348752914,0.7417718580072862
2,468
Steroid metabolism
6
24
2.266274
0.023435
O76062,Q15392,P04062,Q9UBM7,Q15800,Q14739
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
102,47,49,51,114,63
696,2114,102,1798,49,496,1838,995,1296,1772,383,1339,1680,1884,63,2370,47,2437,114,121,2178,51,775,1219
0.3186451392955738,-0.7915396678024824,1.8643955467119475,-0.49788927155059765,2.644481441197411,0.565601265268559,-0.5237411060737124,0.05627090662211817,-0.15189356987392963,-0.4721974863524341,0.7225559645801342,-0.17567657782693433,-0.3960622793653552,-0.5497550639890549,2.364853829476893,-1.322298943353699,2.705604207310635,-2.15778072649351,1.7448358781713682,1.6991299075669488,-0.8472453003312823,2.5949584998787207,0.2545732583950417,-0.08134699713241711
2,468
Cysteine protease
13
29
2.260172
0.023811
O60343,P42575,Q13510,Q92820,P17812,Q92643,Q06203,Q93009,P07858,Q4KMP7,P08243,Q8TC07,Q96FW1
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
325,236,112,376,497,449,563,472,24,248,186,250,220
325,1763,24,186,497,1838,876,2263,236,996,581,1420,2048,563,964,112,965,1002,248,1946,1209,250,449,376,472,220,1434,669,1083
0.8552711400416021,-0.4721974863524341,3.316440414035143,1.3148080906459898,0.565601265268559,-0.5237411060737124,0.14556503368975818,-0.9898924303408787,1.0912400876291406,0.05627090662211817,0.4644562459753665,-0.22365336069552152,-0.7093648604789845,0.4848802844441598,0.07877351189206046,1.7750387384721054,0.07877351189206046,0.05627090662211817,1.0557791765577014,-0.6022778524744863,-0.08134699713241711,1.0557791765577014,0.6448072914475071,0.7417718580072862,0.6053899682620425,1.1438835156965523,-0.22365336069552152,0.3817551739233301,0.0108995245257502
2,468
Cellular ion homeostasis
22
76
2.257873
0.023954
Q15334,P05023,P62942,P23634,Q8N511,P16615,Q15904,O75503,Q7L0J3,P55061,P50897,Q9Y487,Q93050,Q00535,P0CG08,Q9HD20,P04920,Q9HC07,P09429,P28482,Q9UJZ1,P78417
Processes and pathways
GO Biological process
msigdb_gobp
513,509,271,396,16,394,290,32,38,543,39,62,68,328,432,81,209,234,357,498,519,127
798,1586,1120,1587,2140,828,32,985,1360,1901,761,2179,591,209,509,1707,1328,1546,2180,357,1668,432,701,955,702,1266,394,1411,934,1765,396,1123,1806,2161,498,2120,936,542,39,2123,1375,2047,810,543,1058,1161,271,127,1881,328,2218,789,513,290,882,768,38,1752,16,1391,814,68,816,1012,1499,2177,1351,890,234,81,1113,738,519,1081,62,2067
0.21130916709284053,-0.34606944879987256,-0.03496930883195915,-0.34606944879987256,-0.8192985310386937,0.18950873816397323,3.010346969899404,0.05627090662211817,-0.1995959661077008,-0.5759332603866829,0.2545732583950417,-0.8753826232126409,0.4439327299123976,1.1786210307382605,0.5455653723813071,-0.4212859664531922,-0.17567657782693433,-0.32129657210781537,-0.8753826232126409,0.7609008970028596,-0.3960622793653552,0.6448072914475071,0.3186451392955738,0.07877351189206046,0.3186451392955738,-0.1282453451374523,0.7032523978558017,-0.22365336069552152,0.10115585811536389,-0.4721974863524341,0.7032523978558017,-0.03496930883195915,-0.49788927155059765,-0.8472453003312823,0.565601265268559,-0.7915396678024824,0.10115585811536389,0.5052058365472561,2.8135128951122743,-0.7915396678024824,-0.1995959661077008,-0.7093648604789845,0.21130916709284053,0.5052058365472561,0.0108995245257502,-0.058093817935866696,1.002027140929854,1.6529323959275795,-0.5497550639890549,0.8552711400416021,-0.9037132041831669,0.2329969417200938,0.5455653723813071,0.9658109974394301,0.14556503368975818,0.2545732583950417,2.8488980910832757,-0.44666371637530605,3.661615789484984,-0.1995959661077008,0.21130916709284053,2.338517782432342,0.21130916709284053,0.05627090662211817,-0.27218882129392213,-0.8472453003312823,-0.17567657782693433,0.14556503368975818,1.1088603313127976,2.094000982565671,-0.011972007198974987,0.29739620791205207,0.5455653723813071,0.0108995245257502,2.3779621596515104,-0.7093648604789845
2,468
Amide binding
18
86
2.256167
0.02406
O14773,P40939,Q8TEX9,P24390,Q8WTV0,P21796,Q00688,Q9BYT8,Q14974,P45880,Q15392,P55786,P62942,Q92973,Q9UIQ6,P42892,P07602,Q03519
Functions
GO Molecular function
msigdb_gomf
94,33,227,3,36,6,260,275,238,14,47,110,271,116,19,56,28,246
2448,1182,319,1955,695,2453,94,1664,697,718,1226,1507,279,900,2449,28,1189,2207,418,2429,467,1737,6,2182,2358,3,958,2161,2347,1873,1155,995,1192,2291,592,33,56,14,2044,594,1965,1712,1198,2045,1128,370,1096,110,1454,2348,1059,271,2145,260,2395,1681,246,1242,1686,1459,1989,238,2401,731,47,1647,227,36,1578,116,462,2286,2442,2192,752,1657,275,2110,870,1613,1400,1505,388,476,19,1866
-2.4782507088829866,-0.08134699713241711,0.8738956173150244,-0.6287910407099505,0.3186451392955738,-2.6900423224636016,1.9374688026168079,-0.3960622793653552,0.3186451392955738,0.29739620791205207,-0.10473033469147558,-0.29667029004619083,0.9839576617525956,0.12341926582388701,-2.5199026771318773,3.198719452250958,-0.08134699713241711,-0.9037132041831669,0.6643789100172187,-1.968994138846055,0.6053899682620425,-0.44666371637530605,4.254918317045912,-0.8753826232126409,-1.2598242554926813,4.4061529638753205,0.07877351189206046,-0.8472453003312823,-1.1982874368625742,-0.5497550639890549,-0.058093817935866696,0.05627090662211817,-0.08134699713241711,-1.0483638394041492,0.4439327299123976,2.9876441146417414,2.5069145047989934,3.796269049554577,-0.7093648604789845,0.4439327299123976,-0.6287910407099505,-0.4212859664531922,-0.08134699713241711,-0.7093648604789845,-0.03496930883195915,0.7417718580072862,-0.011972007198974987,1.7900609938314576,-0.24785041714148484,-1.1982874368625742,0.0108995245257502,1.002027140929854,-0.8192985310386937,1.0200201103056432,-1.5156579856510553,-0.3960622793653552,1.0557791765577014,-0.10473033469147558,-0.3960622793653552,-0.24785041714148484,-0.6554750699704857,1.0912400876291406,-1.5487932064905703,0.29739620791205207,2.705604207310635,-0.3709907348752914,1.1264079353050018,2.8839991952794084,-0.32129657210781537,1.7448358781713682,0.6251446041977697,-1.0190242872589113,-2.2752985103774694,-0.8753826232126409,0.27603929431054613,-0.3709907348752914,1.002027140929854,-0.7639661184612422,0.16759443900767257,-0.34606944879987256,-0.1995959661077008,-0.27218882129392213,0.7225559645801342,0.6053899682620425,3.542845976168228,-0.5237411060737124
2,468
Oxidoreductase activity
27
182
2.24882
0.024524
Q8N4Q0,O43169,Q8NB78,P30519,Q9UDW1,Q16134,P40939,Q9UHG3,O43676,P14406,Q15392,P11310,Q9UBM7,Q14739,P48735,Q9NZ01,O15121,Q3SXM5,Q06136,O76062,O75874,Q15800,Q9BU89,Q16850,Q9H6W3,O00116,P78417
Functions
GO Molecular function
msigdb_gomf
1,5,7,21,151,31,33,44,45,170,47,175,51,63,66,70,86,98,97,102,104,114,120,121,124,123,127
123,1184,1834,1224,1052,381,86,5,827,45,1120,2138,2227,719,217,2373,984,1957,104,1901,102,2345,393,305,1733,1229,700,245,410,1589,1706,279,1798,1327,2322,1902,1903,986,2116,1545,2261,2091,1668,1591,1804,1509,2247,175,2458,903,1627,1032,857,1981,1091,2209,170,2181,1928,2433,326,2160,2093,720,1838,1766,833,2094,1806,2367,1370,1984,1333,807,1807,2327,21,1191,1448,540,763,1808,1673,2311,2095,2012,1483,2299,2013,2391,33,1269,66,1554,594,1055,1965,1516,2279,1934,441,2416,878,2016,1812,612,2167,1813,1715,1879,127,1938,2395,1560,97,1815,1307,344,296,63,400,1913,47,2437,114,31,2422,812,351,121,1250,1069,98,2411,1605,1138,621,313,637,239,638,1571,2081,844,412,2026,547,176,2402,1,2423,7,1531,2315,1890,1392,1578,1533,1499,2455,1434,311,2178,752,2306,120,1285,124,1613,1658,2428,70,51,1831,1895,151,44,1219,1728,1758,1082,254
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2,468
Alzheimers disease and mirna effects
24
76
2.238629
0.02518
P51665,P21796,P45880,P16615,P28072,Q9NQC3,P49721,P28074,Q9Y277,P12235,P20618,Q00535,O43242,O95197,P28070,Q96GC9,Q92542,O14654,P14735,P49327,P60900,P49720,P28482,Q9NSK0
Processes and pathways
WikiPathways
msigdb_wp
511,6,14,394,268,149,26,42,178,558,559,328,575,75,457,473,339,216,467,594,501,500,498,122
1898,1794,216,1796,575,75,1231,1903,1590,1408,1763,1265,701,558,931,467,394,1736,989,804,559,6,1332,1447,1511,1929,1123,1767,457,268,42,498,2347,1094,1674,2073,723,1037,2263,2144,14,1418,593,594,500,26,704,511,1379,501,1381,1814,1060,1241,328,841,673,1242,1064,1340,1604,706,1391,339,473,885,793,1281,1109,2178,1973,1110,149,122,1699,178
-0.5759332603866829,-0.49788927155059765,1.1612876806907628,-0.49788927155059765,0.4644562459753665,2.2315443900172007,-0.10473033469147558,-0.5759332603866829,-0.34606944879987256,-0.22365336069552152,-0.4721974863524341,-0.1282453451374523,0.3186451392955738,0.4848802844441598,0.10115585811536389,0.6053899682620425,0.7032523978558017,-0.44666371637530605,0.05627090662211817,0.21130916709284053,0.4848802844441598,4.254918317045912,-0.17567657782693433,-0.24785041714148484,-0.29667029004619083,-0.6022778524744863,-0.03496930883195915,-0.4721974863524341,0.6251446041977697,1.002027140929854,2.741870933531249,0.565601265268559,-1.1982874368625742,-0.011972007198974987,-0.3960622793653552,-0.7365753446833382,0.29739620791205207,0.033646699417906,-0.9898924303408787,-0.8192985310386937,3.796269049554577,-0.22365336069552152,0.4439327299123976,0.4439327299123976,0.565601265268559,3.252619812053995,0.3186451392955738,0.5455653723813071,-0.1995959661077008,0.565601265268559,-0.1995959661077008,-0.49788927155059765,0.0108995245257502,-0.10473033469147558,0.8552711400416021,0.18950873816397323,0.3608235263603773,-0.10473033469147558,0.0108995245257502,-0.17567657782693433,-0.34606944879987256,0.3186451392955738,-0.1995959661077008,0.8177749042593478,0.6053899682620425,0.14556503368975818,0.2329969417200938,-0.1282453451374523,-0.011972007198974987,-0.8472453003312823,-0.6287910407099505,-0.011972007198974987,1.51127818869554,1.6991299075669488,-0.3960622793653552,1.3481865209735655
2,468
Secretory vesicle
44
221
2.233936
0.025487
P45880,P42785,P30519,Q9UQB8,P14174,P07858,P16278,O00429,P07602,Q9NTK5,O00231,Q7L0J3,P50897,Q7L576,Q07065,P78310,Q99536,Q08380,P42892,P06280,Q8NF37,P10619,Q9Y487,P04066,P12956,Q93050,O43760,P15586,Q9H0U3,Q92542,O15121,O00584,Q9BTY2,Q9Y6I9,P09960,O75874,O00754,P06865,Q14974,Q13510,P09429,Q92820,Q9HBM0,Q9NZJ7
Localization
GO Cellular component
msigdb_gocc
14,17,21,22,280,24,25,152,28,291,284,38,39,298,295,294,311,308,56,187,315,61,62,189,321,68,320,207,335,339,86,342,100,369,103,104,231,232,238,112,357,376,377,388
1833,1439,284,1898,1182,152,1794,1440,342,231,86,631,1978,575,1475,522,1900,320,1225,1587,760,896,985,104,2038,1798,2245,189,1836,782,187,783,1329,232,2206,1763,1265,28,1546,2071,24,1031,1189,1802,357,2207,1591,103,1624,1906,701,494,418,61,2399,1960,930,1669,433,1032,1033,321,1190,1478,956,280,1735,1628,207,2040,25,1411,510,395,1736,1549,1871,1837,804,934,1232,680,1364,559,762,1447,703,1806,2161,1767,498,1333,21,2120,1672,2164,541,1035,1236,2073,2466,2143,2291,542,1633,1195,1156,17,56,14,1416,684,1811,39,1038,742,1713,2123,726,511,1271,1129,1272,1056,2074,2125,1299,1878,2168,1641,615,1642,1058,1557,2019,616,1241,1426,294,743,1559,295,308,864,1244,2149,1307,1684,1064,1744,1564,1816,1989,112,998,1885,966,1566,1747,238,706,1342,1718,513,384,707,1388,1168,599,2171,527,38,298,1528,1430,469,2027,1889,2315,315,970,339,376,604,68,425,1393,2455,2191,793,1281,311,817,2340,753,100,1317,973,974,1502,1016,335,714,377,1048,291,2087,388,1438,2065,1219,1698,1114,1699,921,22,1321,62,1760,1264,369
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2,468
Ubiquitin ligase complex
17
41
2.233419
0.025521
Q9UJX4,O60566,Q92990,Q16763,Q9UJX3,Q9UJX2,O75150,Q9BUN8,Q96P70,Q13618,Q96S59,P61962,Q5VTR2,Q9UBU6,Q8N668,Q9HB71,Q9UBV2
Localization
GO Cellular component
msigdb_gocc
488,430,423,261,406,533,12,274,463,372,450,93,445,90,314,192,518
430,12,1956,856,1371,1422,93,545,1061,2233,2099,372,1165,1428,2188,1068,261,445,1430,314,423,1044,712,463,450,2135,1255,274,692,192,1260,90,518,2154,533,406,488,1148,1022,648,1793
0.6448072914475071,3.926954124542245,-0.6287910407099505,0.16759443900767257,-0.1995959661077008,-0.22365336069552152,1.9519359610196718,0.5052058365472561,0.0108995245257502,-0.9322398063664452,-0.7639661184612422,0.7417718580072862,-0.058093817935866696,-0.22365336069552152,-0.8753826232126409,0.0108995245257502,1.0200201103056432,0.6448072914475071,-0.22365336069552152,0.8924386609086673,0.6643789100172187,0.033646699417906,0.3186451392955738,0.6251446041977697,0.6448072914475071,-0.7915396678024824,-0.10473033469147558,1.002027140929854,0.33978721059520445,1.281166698194264,-0.10473033469147558,1.9807254988103864,0.5455653723813071,-0.8192985310386937,0.5254338786156286,0.7032523978558017,0.5855424906777212,-0.03496930883195915,0.05627090662211817,0.4025832237568715,-0.4721974863524341
2,468
Myoclonic seizure
14
43
2.22244
0.026254
O75503,Q96N66,O60566,Q9Y3E5,Q9HA77,Q01105,Q13510,P04062,P40763,P16278,O00429,P07602,Q9Y619,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,316,430,368,464,145,112,49,188,25,152,28,292,388
152,1586,827,576,2308,430,32,49,28,1546,1445,25,720,1448,188,765,1055,2124,2416,1199,1132,145,1384,864,112,1566,1489,944,884,1312,1533,2286,2191,316,1580,464,388,1178,489,1866,368,2067,292
1.4952459017765753,-0.34606944879987256,0.18950873816397323,0.4644562459753665,-1.1076784324720763,0.6448072914475071,3.010346969899404,2.644481441197411,3.198719452250958,-0.32129657210781537,-0.24785041714148484,3.273996348775714,0.29739620791205207,-0.24785041714148484,1.2980205320115141,0.2545732583950417,0.0108995245257502,-0.7915396678024824,-1.6840940352377014,-0.08134699713241711,-0.03496930883195915,1.5431638652413855,-0.1995959661077008,0.16759443900767257,1.7750387384721054,-0.32129657210781537,-0.27218882129392213,0.10115585811536389,0.14556503368975818,-0.15189356987392963,-0.29667029004619083,-1.0190242872589113,-0.8753826232126409,0.8924386609086673,-0.32129657210781537,0.6251446041977697,0.7225559645801342,-0.058093817935866696,0.5855424906777212,-0.5237411060737124,0.7609008970028596,-0.7093648604789845,0.9658109974394301
2,468
Ion homeostasis
25
89
2.210733
0.027054
Q15334,P05023,Q8N511,P62942,P23634,P16615,P30519,Q15904,O75503,Q12955,Q7L0J3,P55061,P50897,Q8N668,Q9Y487,Q93050,Q00535,P0CG08,Q9HD20,P04920,Q9HC07,P09429,P28482,Q9UJZ1,P78417
Processes and pathways
GO Biological process
msigdb_gobp
513,509,16,271,396,394,21,290,32,546,38,543,39,314,62,68,328,432,81,209,234,357,498,519,127
798,1586,1326,1120,1587,2140,828,32,985,1360,1901,1666,761,2179,591,1407,209,509,1707,1328,1546,2180,357,1668,1547,432,701,955,702,1266,394,1411,934,1765,396,1123,1806,2161,498,21,1293,2120,936,542,2419,39,2123,1375,2047,810,543,1058,1161,271,879,127,1881,328,2218,546,1989,1460,789,513,290,882,768,38,1752,2402,16,314,1391,814,68,816,1012,1499,2177,1351,890,234,81,1113,738,519,1081,62,2067
0.21130916709284053,-0.34606944879987256,-0.17567657782693433,-0.03496930883195915,-0.34606944879987256,-0.8192985310386937,0.18950873816397323,3.010346969899404,0.05627090662211817,-0.1995959661077008,-0.5759332603866829,-0.3960622793653552,0.2545732583950417,-0.8753826232126409,0.4439327299123976,-0.22365336069552152,1.1786210307382605,0.5455653723813071,-0.4212859664531922,-0.17567657782693433,-0.32129657210781537,-0.8753826232126409,0.7609008970028596,-0.3960622793653552,-0.32129657210781537,0.6448072914475071,0.3186451392955738,0.07877351189206046,0.3186451392955738,-0.1282453451374523,0.7032523978558017,-0.22365336069552152,0.10115585811536389,-0.4721974863524341,0.7032523978558017,-0.03496930883195915,-0.49788927155059765,-0.8472453003312823,0.565601265268559,3.368926559380632,-0.15189356987392963,-0.7915396678024824,0.10115585811536389,0.5052058365472561,-1.7534682900989214,2.8135128951122743,-0.7915396678024824,-0.1995959661077008,-0.7093648604789845,0.21130916709284053,0.5052058365472561,0.0108995245257502,-0.058093817935866696,1.002027140929854,0.14556503368975818,1.6529323959275795,-0.5497550639890549,0.8552711400416021,-0.9037132041831669,0.5052058365472561,-0.6554750699704857,-0.24785041714148484,0.2329969417200938,0.5455653723813071,0.9658109974394301,0.14556503368975818,0.2545732583950417,2.8488980910832757,-0.44666371637530605,-1.5487932064905703,3.661615789484984,0.8924386609086673,-0.1995959661077008,0.21130916709284053,2.338517782432342,0.21130916709284053,0.05627090662211817,-0.27218882129392213,-0.8472453003312823,-0.17567657782693433,0.14556503368975818,1.1088603313127976,2.094000982565671,-0.011972007198974987,0.29739620791205207,0.5455653723813071,0.0108995245257502,2.3779621596515104,-0.7093648604789845
2,468
Cholesterol metabolism with bloch and kandutschrussell pathways
7
23
2.203496
0.02756
O76062,Q15392,Q9UBM7,Q15800,Q16850,O95864,Q14739
Processes and pathways
WikiPathways
msigdb_wp
102,47,51,114,121,245,63
1052,925,102,1544,245,496,994,995,1296,1197,594,1772,1680,1884,296,63,2370,47,2437,114,121,1535,51
0.0108995245257502,0.10115585811536389,1.8643955467119475,-0.32129657210781537,1.0557791765577014,0.565601265268559,0.05627090662211817,0.05627090662211817,-0.15189356987392963,-0.08134699713241711,0.4439327299123976,-0.4721974863524341,-0.3960622793653552,-0.5497550639890549,0.9475864635773026,2.364853829476893,-1.322298943353699,2.705604207310635,-2.15778072649351,1.7448358781713682,1.6991299075669488,-0.29667029004619083,2.5949584998787207
2,468
Abnormal mitral valve physiology
9
34
2.188722
0.028617
P40939,O00170,O00754,P06280,P04062,P21359,O95169,O75844,P53701
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,349,231,187,49,144,305,185,59
349,231,1120,984,2007,185,305,1188,2142,49,187,1480,144,1154,498,1295,33,1876,594,1376,59,612,2167,1845,1773,1460,880,1776,1494,1392,1012,1505,1660,380
0.7799438888928811,1.1088603313127976,-0.03496930883195915,0.05627090662211817,-0.6823322307636482,1.3148080906459898,0.9109010031706256,-0.08134699713241711,-0.8192985310386937,2.644481441197411,1.2980205320115141,-0.27218882129392213,1.5431638652413855,-0.058093817935866696,0.565601265268559,-0.15189356987392963,2.9876441146417414,-0.5497550639890549,0.4439327299123976,-0.1995959661077008,2.417051334666312,0.4233087298229898,-0.8472453003312823,-0.5237411060737124,-0.4721974863524341,-0.24785041714148484,0.14556503368975818,-0.4721974863524341,-0.27218882129392213,-0.1995959661077008,0.05627090662211817,-0.27218882129392213,-0.3709907348752914,0.7417718580072862
2,468
Dysmetria
13
42
2.18697
0.028745
O75503,Q9UBB4,O14773,Q5JRX3,Q9Y3E5,Q69YN2,P54136,Q96BR5,Q8IV08,P21359,Q8N0X7,O15121,Q6DKK2
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
32,258,94,196,368,201,105,360,92,144,249,86,155
2337,94,853,778,86,779,828,1730,32,985,1763,2415,144,836,1295,1840,1157,105,1773,1063,864,675,1776,196,1647,201,155,1821,1008,92,249,360,2058,1214,516,258,1895,2318,1660,368,380,2067
-1.167861727972861,1.9374688026168079,0.16759443900767257,0.2329969417200938,2.023552801349019,0.2329969417200938,0.18950873816397323,-0.44666371637530605,3.010346969899404,0.05627090662211817,-0.4721974863524341,-1.6840940352377014,1.5431638652413855,0.18950873816397323,-0.15189356987392963,-0.5237411060737124,-0.058093817935866696,1.834815592336478,-0.4721974863524341,0.0108995245257502,0.16759443900767257,0.3608235263603773,-0.4721974863524341,1.2472580264373727,-0.3709907348752914,1.2302020821665278,1.4791533652051556,-0.49788927155059765,0.05627090662211817,1.966354748749709,1.0557791765577014,0.7609008970028596,-0.7093648604789845,-0.08134699713241711,0.5455653723813071,1.0379372362963877,-0.5497550639890549,-1.1076784324720763,-0.3709907348752914,0.7609008970028596,0.7417718580072862,-0.7093648604789845
2,468
Asparagine n linked glycosylation
34
96
2.183947
0.028966
Q15363,P24390,Q9BT22,Q9BUN8,Q13561,P46977,P16278,P35606,Q12955,P61923,P62820,Q9HCU5,Q9NR45,P10619,P04066,P18085,Q14203,O75935,Q9Y3B3,Q9H0U3,Q9UJW0,Q9Y678,Q92538,Q15436,O15027,Q9Y3Q3,Q2TAA5,Q08379,Q14789,P49257,P63167,O14653,Q8NFW8,Q9UBV2
Processes and pathways
Reactome Pathways
msigdb_reactome
384,3,140,274,273,523,25,411,546,544,420,312,452,61,189,436,583,431,206,335,215,609,471,218,466,356,620,483,233,111,616,490,374,518
1474,1026,490,778,466,1703,1476,1956,1925,431,1228,189,1231,901,1443,61,2210,25,436,3,2161,1710,2327,2390,411,1633,1676,523,1095,653,1417,111,684,1377,1772,1272,1097,1039,1637,2215,2074,1556,1936,544,1381,420,616,1241,1302,964,483,618,1133,546,730,1134,273,1716,998,1604,966,583,1566,1524,233,384,218,943,620,2025,1253,374,1693,471,1010,1045,1857,713,140,1973,274,1110,973,335,1319,312,452,1863,518,215,206,356,2243,1322,609,1264
-0.27218882129392213,0.033646699417906,0.565601265268559,0.2329969417200938,0.6053899682620425,-0.4212859664531922,-0.27218882129392213,-0.6287910407099505,-0.6022778524744863,0.6448072914475071,-0.10473033469147558,1.281166698194264,-0.10473033469147558,0.12341926582388701,-0.24785041714148484,2.3910310244631345,-0.9037132041831669,3.273996348775714,0.6448072914475071,4.4061529638753205,-0.8472453003312823,-0.4212859664531922,-1.137659851909859,-1.4827895539405542,0.6838603272070093,-0.3709907348752914,-0.3960622793653552,0.5254338786156286,-0.011972007198974987,0.3817551739233301,-0.22365336069552152,1.7750387384721054,0.33978721059520445,-0.1995959661077008,-0.4721974863524341,-0.1282453451374523,-0.011972007198974987,0.033646699417906,-0.3709907348752914,-0.9037132041831669,-0.7365753446833382,-0.32129657210781537,-0.6022778524744863,0.5052058365472561,-0.1995959661077008,0.6643789100172187,0.4233087298229898,-0.10473033469147558,-0.15189356987392963,0.07877351189206046,0.5855424906777212,0.4233087298229898,-0.03496930883195915,0.5052058365472561,0.29739620791205207,-0.03496930883195915,1.002027140929854,-0.4212859664531922,0.05627090662211817,-0.34606944879987256,0.07877351189206046,0.4644562459753665,-0.32129657210781537,-0.29667029004619083,1.1088603313127976,0.7225559645801342,1.1438835156965523,0.10115585811536389,0.4233087298229898,-0.6823322307636482,-0.10473033469147558,0.7417718580072862,-0.3960622793653552,0.6053899682620425,0.05627090662211817,0.033646699417906,-0.5237411060737124,0.3186451392955738,1.5748140446524133,-0.6287910407099505,1.002027140929854,-0.011972007198974987,0.07877351189206046,0.8365644866172669,-0.15189356987392963,0.9109010031706256,0.6448072914475071,-0.5237411060737124,0.5455653723813071,1.1786210307382605,1.2130776498207292,0.7799438888928811,-0.9322398063664452,-0.15189356987392963,0.4439327299123976,-0.10473033469147558
2,468
Golgi associated vesicle
8
27
2.182236
0.029092
Q15363,P24390,Q9HD26,O43493,Q9Y3B3,Q8N511,Q9Y3Q3,P35606
Localization
GO Cellular component
msigdb_gocc
384,3,364,169,206,16,356,411
1026,169,2037,1979,2207,433,3,411,1417,684,726,1272,1097,1299,1641,544,1132,1275,384,16,1693,973,364,1471,206,356,609
0.033646699417906,1.38130620151236,-0.7093648604789845,-0.6554750699704857,-0.9037132041831669,0.6448072914475071,4.4061529638753205,0.6838603272070093,-0.22365336069552152,0.33978721059520445,0.29739620791205207,-0.1282453451374523,-0.011972007198974987,-0.15189356987392963,-0.3709907348752914,0.5052058365472561,-0.03496930883195915,-0.1282453451374523,0.7225559645801342,3.661615789484984,-0.3960622793653552,0.07877351189206046,0.7609008970028596,-0.24785041714148484,1.2130776498207292,0.7799438888928811,0.4439327299123976
2,468
Endomembrane system organization
41
145
2.15491
0.031169
Q9H270,Q9P2W9,Q15363,Q99816,Q969M3,Q8TBA6,Q96CP7,P46379,P16615,Q9NQC3,Q9UQB8,O00429,O75122,P62820,P57088,Q15042,Q86XL3,O75694,Q00765,O75844,Q9H6U6,O43760,Q16739,O95197,O14964,Q9Y3B3,Q15629,Q96GC9,O15121,Q14108,Q92538,Q8N1F7,O15027,Q9Y3Q3,Q8N4V1,Q08379,Q9Y2J2,Q14789,Q9UL15,P49257,P40616
Processes and pathways
GO Biological process
msigdb_gobp
257,129,384,264,403,402,15,269,394,149,22,152,160,420,303,444,54,180,307,185,318,320,72,75,330,206,79,473,86,87,471,470,466,356,352,483,367,233,507,111,358
1833,152,1586,777,330,610,466,86,632,717,1475,1900,320,924,2068,1476,160,896,1406,1925,2421,180,185,1442,929,1228,75,2179,2142,1030,2180,394,2277,2415,805,1123,498,1035,723,358,765,269,1676,593,111,684,809,1677,2123,1056,303,2125,1878,2168,2348,420,1424,307,1302,841,483,1244,1133,546,674,1562,730,87,940,583,233,2381,881,444,1777,1914,384,79,72,1388,1390,2025,565,2171,710,813,1528,54,642,884,470,352,911,1608,1465,2285,660,912,402,603,471,1532,403,816,15,622,473,264,2253,1283,1997,1656,868,973,714,257,948,318,892,1048,1537,1538,149,1726,1438,129,2065,646,2088,1220,507,951,608,759,647,22,1864,367,1792,1116,1223,206,356,1760,2112
-0.5237411060737124,1.4952459017765753,-0.34606944879987256,0.2329969417200938,0.8365644866172669,0.4233087298229898,0.6053899682620425,2.023552801349019,0.4025832237568715,0.29739620791205207,-0.27218882129392213,-0.5759332603866829,0.8738956173150244,0.10115585811536389,-0.7365753446833382,-0.27218882129392213,1.430509532064174,0.12341926582388701,-0.22365336069552152,-0.6022778524744863,-1.7886042606720733,1.3315299103873544,1.3148080906459898,-0.24785041714148484,0.10115585811536389,-0.10473033469147558,2.2315443900172007,-0.8753826232126409,-0.8192985310386937,0.033646699417906,-0.8753826232126409,0.7032523978558017,-1.0190242872589113,-1.6840940352377014,0.21130916709284053,-0.03496930883195915,0.565601265268559,0.033646699417906,0.29739620791205207,0.7609008970028596,0.2545732583950417,1.002027140929854,-0.3960622793653552,0.4439327299123976,1.7750387384721054,0.33978721059520445,0.21130916709284053,-0.3960622793653552,-0.7915396678024824,0.0108995245257502,0.9292833665100879,-0.7915396678024824,-0.5497550639890549,-0.8472453003312823,-1.1982874368625742,0.6643789100172187,-0.22365336069552152,0.9109010031706256,-0.15189356987392963,0.18950873816397323,0.5855424906777212,-0.10473033469147558,-0.03496930883195915,0.5052058365472561,0.3608235263603773,-0.32129657210781537,0.29739620791205207,2.0093242006690732,0.10115585811536389,0.4644562459753665,1.1088603313127976,-1.4178355631317874,0.14556503368975818,0.6448072914475071,-0.4721974863524341,-0.5759332603866829,0.7225559645801342,2.1495441875593015,2.312020878410862,-0.1995959661077008,-0.1995959661077008,-0.6823322307636482,0.4848802844441598,-0.8472453003312823,0.3186451392955738,0.21130916709284053,-0.29667029004619083,2.5699842709784817,0.4025832237568715,0.14556503368975818,0.6053899682620425,0.7799438888928811,0.12341926582388701,-0.34606944879987256,-0.24785041714148484,-1.0190242872589113,0.3817551739233301,0.12341926582388701,0.7032523978558017,0.4439327299123976,0.6053899682620425,-0.29667029004619083,0.7032523978558017,0.21130916709284053,3.671370822301053,0.4233087298229898,0.6053899682620425,1.0200201103056432,-0.9609652532252494,-0.1282453451374523,-0.6554750699704857,-0.3709907348752914,0.16759443900767257,0.07877351189206046,0.3186451392955738,1.0379372362963877,0.10115585811536389,0.8924386609086673,0.14556503368975818,0.033646699417906,-0.29667029004619083,-0.29667029004619083,1.51127818869554,-0.4212859664531922,-0.22365336069552152,1.6529323959275795,-0.7093648604789845,0.4025832237568715,-0.7365753446833382,-0.08134699713241711,0.565601265268559,0.10115585811536389,0.4439327299123976,0.27603929431054613,0.4025832237568715,3.368926559380632,-0.5237411060737124,0.7609008970028596,-0.4721974863524341,-0.011972007198974987,-0.08134699713241711,1.2130776498207292,0.7799438888928811,-0.44666371637530605,-0.7639661184612422
2,468
Nucleoside triphosphatase regulator activity
19
58
2.152965
0.031321
Q02818,Q15437,P49770,P21359,P80303,O00429,Q9NR50,Q9HCU5,Q15042,O00410,P18085,O60343,P55010,Q9P035,Q15436,Q9H6Z4,Q14185,Q8TC07,Q4KMP7
Functions
GO Molecular function
msigdb_gomf
130,133,270,144,23,152,428,312,444,319,436,325,334,214,218,354,237,250,248
319,152,325,1868,650,436,2277,144,2041,1738,1294,1553,1450,1416,270,1198,1811,1635,334,616,23,1275,130,1521,656,940,237,1818,789,658,444,513,218,133,248,1690,2171,1691,1253,250,471,1011,1498,1612,1213,1016,948,1353,354,312,428,214,895,1177,1832,1051,669,2440
0.8738956173150244,1.4952459017765753,0.8552711400416021,-0.5497550639890549,0.3817551739233301,0.6448072914475071,-1.0190242872589113,1.5431638652413855,-0.7093648604789845,-0.44666371637530605,-0.15189356987392963,-0.32129657210781537,-0.24785041714148484,-0.22365336069552152,1.002027140929854,-0.08134699713241711,-0.49788927155059765,-0.3709907348752914,0.8365644866172669,0.4233087298229898,3.326987798371381,-0.1282453451374523,1.637422094920818,-0.29667029004619083,0.3817551739233301,0.10115585811536389,1.0912400876291406,-0.49788927155059765,0.2329969417200938,0.3817551739233301,0.6448072914475071,0.5455653723813071,1.1438835156965523,1.6062322929490631,1.0557791765577014,-0.3960622793653552,-0.8472453003312823,-0.3960622793653552,-0.10473033469147558,1.0557791765577014,0.6053899682620425,0.05627090662211817,-0.27218882129392213,-0.34606944879987256,-0.08134699713241711,0.05627090662211817,0.10115585811536389,-0.17567657782693433,0.7799438888928811,0.9109010031706256,0.6643789100172187,1.1786210307382605,0.14556503368975818,-0.058093817935866696,-0.49788927155059765,0.033646699417906,0.3817551739233301,-2.235771034953379
2,468
Oxidoreductase
21
135
2.151743
0.031418
Q8N4Q0,Q8NB78,P30519,Q16134,P40939,Q9UHG3,Q15392,P11310,Q9UBM7,Q14739,P48735,Q9NZ01,O15121,Q06136,O76062,O75874,Q15800,Q9BU89,Q16850,Q9H6W3,P78417
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
1,7,21,31,33,44,47,175,51,63,66,70,86,97,102,104,114,120,121,124,127
1184,1224,1052,381,86,827,2227,719,217,2373,984,1957,104,102,2345,700,245,1589,1706,279,1798,1327,1903,986,2116,2261,1668,1591,2247,175,2458,1627,1032,857,1091,2181,1928,2433,326,2160,720,1838,1766,833,2094,2367,1370,1984,1333,807,1807,21,1191,1448,540,1808,1673,2311,2095,1483,2013,2391,33,1269,66,1554,594,1055,1965,1516,2279,441,2416,878,2016,1812,612,1813,127,1938,2395,1560,97,1815,1307,296,63,400,47,2437,114,31,351,121,1250,1069,2411,1605,1138,621,637,239,638,2081,844,412,2026,547,176,2402,1,2423,7,1531,2315,1890,1392,1578,1533,1499,311,2178,752,120,124,1613,1658,2428,70,51,1831,1895,44,1219,1728
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2,468
Alzheimers disease
23
74
2.150738
0.031497
P51665,P21796,P45880,P16615,P28072,Q9NQC3,P49721,P28074,Q9Y277,P12235,P20618,Q00535,O43242,O95197,P28070,Q92542,O14654,P14735,P49327,P60900,P49720,P28482,Q9NSK0
Processes and pathways
WikiPathways
msigdb_wp
511,6,14,394,268,149,26,42,178,558,559,328,575,75,457,339,216,467,594,501,500,498,122
1898,1794,216,1796,575,75,1231,1903,1590,1408,1763,1265,701,558,931,467,394,1736,989,804,559,6,1332,1447,1511,1929,1123,1767,457,268,42,498,2347,1094,1674,2073,723,1037,2263,2144,14,1418,593,594,500,26,704,511,1379,501,1381,1814,1060,1241,328,841,673,1242,1064,1340,1604,706,1391,339,793,1281,1109,2178,1973,1110,149,122,1699,178
-0.5759332603866829,-0.49788927155059765,1.1612876806907628,-0.49788927155059765,0.4644562459753665,2.2315443900172007,-0.10473033469147558,-0.5759332603866829,-0.34606944879987256,-0.22365336069552152,-0.4721974863524341,-0.1282453451374523,0.3186451392955738,0.4848802844441598,0.10115585811536389,0.6053899682620425,0.7032523978558017,-0.44666371637530605,0.05627090662211817,0.21130916709284053,0.4848802844441598,4.254918317045912,-0.17567657782693433,-0.24785041714148484,-0.29667029004619083,-0.6022778524744863,-0.03496930883195915,-0.4721974863524341,0.6251446041977697,1.002027140929854,2.741870933531249,0.565601265268559,-1.1982874368625742,-0.011972007198974987,-0.3960622793653552,-0.7365753446833382,0.29739620791205207,0.033646699417906,-0.9898924303408787,-0.8192985310386937,3.796269049554577,-0.22365336069552152,0.4439327299123976,0.4439327299123976,0.565601265268559,3.252619812053995,0.3186451392955738,0.5455653723813071,-0.1995959661077008,0.565601265268559,-0.1995959661077008,-0.49788927155059765,0.0108995245257502,-0.10473033469147558,0.8552711400416021,0.18950873816397323,0.3608235263603773,-0.10473033469147558,0.0108995245257502,-0.17567657782693433,-0.34606944879987256,0.3186451392955738,-0.1995959661077008,0.8177749042593478,0.2329969417200938,-0.1282453451374523,-0.011972007198974987,-0.8472453003312823,-0.6287910407099505,-0.011972007198974987,1.51127818869554,1.6991299075669488,-0.3960622793653552,1.3481865209735655
2,468
Cellular modified amino acid metabolic process
13
40
2.143693
0.032057
Q9NRN7,P16435,O75874,Q9H2D1,Q9BZF1,P23786,Q9UHG3,P34896,P11310,O60725,P00374,P07858,P78417
Processes and pathways
GO Biological process
msigdb_gobp
197,326,104,10,172,293,44,76,175,113,279,24,127
1700,1184,113,104,1731,279,1327,2323,24,175,2458,903,955,2159,326,1737,578,293,1234,1984,1963,76,836,2419,2044,1554,1055,127,2147,1571,514,711,376,1434,752,172,10,197,44,1758
-0.4212859664531922,-0.08134699713241711,1.759963827525142,1.8496309709719285,-0.44666371637530605,0.9839576617525956,-0.17567657782693433,-1.137659851909859,3.316440414035143,1.3481865209735655,-3.001354480809533,0.12341926582388701,0.07877351189206046,-0.8472453003312823,0.8552711400416021,-0.44666371637530605,0.4644562459753665,0.9475864635773026,-0.10473033469147558,-0.6554750699704857,-0.6287910407099505,2.217985101813405,0.18950873816397323,-1.7534682900989214,-0.7093648604789845,-0.32129657210781537,0.0108995245257502,1.6529323959275795,-0.8192985310386937,-0.32129657210781537,0.5455653723813071,0.3186451392955738,0.7417718580072862,-0.22365336069552152,0.27603929431054613,1.38130620151236,4.0449565332869035,1.2472580264373727,2.729815482669204,-0.44666371637530605
2,468
Functional abnormality of the gastrointestinal tract
39
216
2.139399
0.032403
Q9UBB4,Q01105,P21359,P11802,O00429,O75569,P07602,Q9Y619,P08183,Q8NBU5,P29372,P04062,Q9UBM7,P63241,P42892,O95169,P06280,P40763,Q14739,Q8IZA0,P48735,Q99720,P15586,P27635,Q14108,Q15436,Q96J02,P50851,O15269,O15143,O75874,O00754,P54136,P49257,Q13510,Q69YQ0,Q6PGP7,Q8N0X7,P55795
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
258,145,144,153,152,277,28,292,286,171,301,49,51,306,56,305,187,188,63,323,66,80,207,85,87,218,228,225,223,101,104,231,105,111,112,241,242,249,126
798,152,2337,231,853,696,101,223,391,827,1120,2259,779,2140,2228,896,984,1957,277,104,1228,305,761,2179,2296,803,1705,2322,2245,1291,49,1231,1799,187,538,28,1444,832,286,2261,1088,1625,153,987,558,2210,207,2040,326,1479,933,1982,2415,1446,1480,144,720,651,1154,1631,740,85,2367,498,301,1984,1448,2311,2390,1674,1295,561,1192,936,723,1483,1675,499,542,1633,188,1911,1711,1373,56,611,682,1126,66,111,594,1237,1965,225,2046,2124,672,1842,1337,1378,1039,1298,105,612,810,2074,1057,126,1715,1421,1239,1454,766,1423,2050,306,1773,1600,2353,1132,145,562,1275,905,841,1560,1202,963,2218,1384,964,864,907,1562,112,87,583,1566,1489,63,1776,400,1914,1247,218,687,1248,1068,1568,812,770,241,1887,1526,1648,1916,242,1572,2284,528,529,813,1782,2371,323,249,1919,1650,171,1852,1010,1072,1578,570,472,1312,816,1012,623,228,2191,2057,1315,2135,2178,80,2085,1213,1973,692,2110,1353,1580,1047,464,1078,1437,1079,1505,388,258,51,1895,821,2318,715,405,1660,920,1262,1661,366,952,380,2067,292
0.21130916709284053,1.4952459017765753,-1.167861727972861,1.1088603313127976,0.16759443900767257,0.3186451392955738,1.8937737203521074,1.1264079353050018,0.7032523978558017,0.18950873816397323,-0.03496930883195915,-0.9898924303408787,0.2329969417200938,-0.8192985310386937,-0.9322398063664452,0.12341926582388701,0.05627090662211817,-0.6287910407099505,0.9839576617525956,1.8496309709719285,-0.10473033469147558,0.9109010031706256,0.2545732583950417,-0.8753826232126409,-1.0779141700680717,0.21130916709284053,-0.4212859664531922,-1.137659851909859,-0.9609652532252494,-0.15189356987392963,2.644481441197411,-0.10473033469147558,-0.49788927155059765,1.2980205320115141,0.5052058365472561,3.198719452250958,-0.24785041714148484,0.18950873816397323,0.9658109974394301,-0.9898924303408787,-0.011972007198974987,-0.3709907348752914,1.4952459017765753,0.05627090662211817,0.4848802844441598,-0.9037132041831669,1.1958841586688884,-0.7093648604789845,0.8552711400416021,-0.27218882129392213,0.10115585811536389,-0.6554750699704857,-1.6840940352377014,-0.24785041714148484,-0.27218882129392213,1.5431638652413855,0.29739620791205207,0.3817551739233301,-0.058093817935866696,-0.3709907348752914,0.27603929431054613,2.0377346622172094,-1.322298943353699,0.565601265268559,0.9292833665100879,-0.6554750699704857,-0.24785041714148484,-1.1076784324720763,-1.4827895539405542,-0.3960622793653552,-0.15189356987392963,0.4848802844441598,-0.08134699713241711,0.10115585811536389,0.29739620791205207,-0.27218882129392213,-0.3960622793653552,0.565601265268559,0.5052058365472561,-0.3709907348752914,1.2980205320115141,-0.5759332603866829,-0.4212859664531922,-0.1995959661077008,2.5069145047989934,0.4233087298229898,0.33978721059520445,-0.03496930883195915,2.338517782432342,1.7750387384721054,0.4439327299123976,-0.10473033469147558,-0.6287910407099505,1.1264079353050018,-0.7093648604789845,-0.7915396678024824,0.3608235263603773,-0.5237411060737124,-0.17567657782693433,-0.1995959661077008,0.033646699417906,-0.15189356987392963,1.834815592336478,0.4233087298229898,0.21130916709284053,-0.7365753446833382,0.0108995245257502,1.6529323959275795,-0.4212859664531922,-0.22365336069552152,-0.10473033469147558,-0.24785041714148484,0.2545732583950417,-0.22365336069552152,-0.7093648604789845,0.9109010031706256,-0.4721974863524341,-0.34606944879987256,-1.228940433793697,-0.03496930883195915,1.5431638652413855,0.4848802844441598,-0.1282453451374523,0.12341926582388701,0.18950873816397323,-0.32129657210781537,-0.08134699713241711,0.07877351189206046,-0.9037132041831669,-0.1995959661077008,0.07877351189206046,0.16759443900767257,0.12341926582388701,-0.32129657210781537,1.7750387384721054,2.0093242006690732,0.4644562459753665,-0.32129657210781537,-0.27218882129392213,2.364853829476893,-0.4721974863524341,0.7032523978558017,-0.5759332603866829,-0.10473033469147558,1.1438835156965523,0.33978721059520445,-0.10473033469147558,0.0108995245257502,-0.32129657210781537,0.21130916709284053,0.2545732583950417,1.073546580138068,-0.5497550639890549,-0.29667029004619083,-0.3709907348752914,-0.5759332603866829,1.073546580138068,-0.32129657210781537,-1.0190242872589113,0.5254338786156286,0.5254338786156286,0.21130916709284053,-0.4721974863524341,-1.322298943353699,0.8738956173150244,1.0557791765577014,-0.5759332603866829,-0.3709907348752914,1.38130620151236,-0.5237411060737124,0.05627090662211817,0.0108995245257502,-0.32129657210781537,0.4848802844441598,0.6053899682620425,-0.15189356987392963,0.21130916709284053,0.05627090662211817,0.4233087298229898,1.1264079353050018,-0.8753826232126409,-0.7093648604789845,-0.15189356987392963,-0.7915396678024824,-0.8472453003312823,2.13572512937309,-0.7365753446833382,-0.08134699713241711,-0.6287910407099505,0.33978721059520445,-0.7639661184612422,-0.17567657782693433,-0.32129657210781537,0.033646699417906,0.6251446041977697,0.0108995245257502,-0.22365336069552152,0.0108995245257502,-0.27218882129392213,0.7225559645801342,1.0379372362963877,2.5949584998787207,-0.5497550639890549,0.21130916709284053,-1.1076784324720763,0.3186451392955738,0.7032523978558017,-0.3709907348752914,0.12341926582388701,-0.10473033469147558,-0.3709907348752914,0.7609008970028596,0.10115585811536389,0.7417718580072862,-0.7093648604789845,0.9658109974394301
2,468
Skin ulcer
9
24
2.138638
0.032465
Q8IZA0,O15269,P48735,O75874,P39210,P04062,P40763,Q03519,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
323,223,66,104,302,49,188,246,63
223,1619,2005,104,803,2142,49,2324,2208,302,188,1452,66,371,2017,1454,1275,246,864,1246,63,1914,323,1504
1.1264079353050018,-0.3709907348752914,-0.6823322307636482,1.8496309709719285,0.21130916709284053,-0.8192985310386937,2.644481441197411,-1.137659851909859,-0.9037132041831669,0.9292833665100879,1.2980205320115141,-0.24785041714148484,2.338517782432342,0.7417718580072862,-0.6823322307636482,-0.24785041714148484,-0.1282453451374523,1.0557791765577014,0.16759443900767257,-0.10473033469147558,2.364853829476893,-0.5759332603866829,0.8738956173150244,-0.27218882129392213
2,468
Abnormality of hepatobiliary system physiology
13
57
2.135923
0.032686
P40939,Q9BT22,P23786,P39210,P11310,Q8N511,P04062,O43772,Q13510,Q6PGP7,O95169,Q96J02,Q9Y619
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,140,293,302,175,16,49,77,112,242,305,228,292
696,77,1120,1619,984,1506,985,305,803,49,2324,2091,1591,175,1154,1233,1122,293,860,2390,936,1414,302,1633,592,33,1911,1373,1812,2167,2292,1555,2020,1063,112,1524,1688,2129,351,944,242,529,16,845,2332,816,228,1695,140,1613,1437,1504,1177,2088,1402,1759,292
0.3186451392955738,2.1907384712256417,-0.03496930883195915,-0.3709907348752914,0.05627090662211817,-0.29667029004619083,0.05627090662211817,0.9109010031706256,0.21130916709284053,2.644481441197411,-1.137659851909859,-0.7639661184612422,-0.34606944879987256,1.3481865209735655,-0.058093817935866696,-0.10473033469147558,-0.03496930883195915,0.9475864635773026,0.16759443900767257,-1.4827895539405542,0.10115585811536389,-0.22365336069552152,0.9292833665100879,-0.3709907348752914,0.4439327299123976,2.9876441146417414,-0.5759332603866829,-0.1995959661077008,-0.49788927155059765,-0.8472453003312823,-1.0483638394041492,-0.32129657210781537,-0.6823322307636482,0.0108995245257502,1.7750387384721054,-0.29667029004619083,-0.3960622793653552,-0.7915396678024824,0.7799438888928811,0.10115585811536389,1.073546580138068,0.5254338786156286,3.661615789484984,0.18950873816397323,-1.137659851909859,0.21130916709284053,1.1264079353050018,-0.3960622793653552,1.5748140446524133,-0.34606944879987256,-0.22365336069552152,-0.27218882129392213,-0.058093817935866696,-0.7365753446833382,-0.1995959661077008,-0.44666371637530605,0.9658109974394301
2,468
Abnormality of bone mineral density
17
111
2.119549
0.034044
Q13126,O75844,Q9HC07,Q5H8A4,Q15392,Q13510,P04062,P21359,P40763,P27635,Q14108,P16278,Q15436,P06280,P07602,Q9Y487,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
35,185,234,139,47,112,49,144,188,85,87,25,218,187,28,62,63
349,1184,231,853,1762,827,1619,2007,2421,392,185,761,803,700,1705,2142,49,2449,2070,1959,187,783,2324,1545,28,495,558,2208,1708,25,1411,933,1671,1480,144,1154,957,85,1983,2311,1674,1295,936,1633,188,1711,1771,878,2409,1271,1199,1378,1200,612,2074,1421,1273,1454,766,2050,1773,2301,1275,841,1560,862,864,35,2232,112,87,1246,63,1688,444,1776,1914,47,218,1248,1069,139,2025,1916,1527,691,1465,2267,570,1312,462,947,1790,692,1353,756,1893,234,515,1437,1079,2086,572,1504,388,1660,1792,1662,62,380,824
0.7799438888928811,-0.08134699713241711,1.1088603313127976,0.16759443900767257,-0.4721974863524341,0.18950873816397323,-0.3709907348752914,-0.6823322307636482,-1.7886042606720733,0.7032523978558017,1.3148080906459898,0.2545732583950417,0.21130916709284053,0.3186451392955738,-0.4212859664531922,-0.8192985310386937,2.644481441197411,-2.5199026771318773,-0.7365753446833382,-0.6287910407099505,1.2980205320115141,0.2329969417200938,-1.137659851909859,-0.32129657210781537,3.198719452250958,0.565601265268559,0.4848802844441598,-0.9037132041831669,-0.4212859664531922,3.273996348775714,-0.22365336069552152,0.10115585811536389,-0.3960622793653552,-0.27218882129392213,1.5431638652413855,-0.058093817935866696,0.07877351189206046,2.0377346622172094,-0.6554750699704857,-1.1076784324720763,-0.3960622793653552,-0.15189356987392963,0.10115585811536389,-0.3709907348752914,1.2980205320115141,-0.4212859664531922,-0.4721974863524341,0.14556503368975818,-1.615882187826786,-0.1282453451374523,-0.08134699713241711,-0.1995959661077008,-0.08134699713241711,0.4233087298229898,-0.7365753446833382,-0.22365336069552152,-0.1282453451374523,-0.24785041714148484,0.2545732583950417,-0.7093648604789845,-0.4721974863524341,-1.0779141700680717,-0.1282453451374523,0.18950873816397323,-0.32129657210781537,0.16759443900767257,0.16759443900767257,2.9072444151690418,-0.9322398063664452,1.7750387384721054,2.0093242006690732,-0.10473033469147558,2.364853829476893,-0.3960622793653552,0.6448072914475071,-0.4721974863524341,-0.5759332603866829,2.705604207310635,1.1438835156965523,-0.10473033469147558,0.0108995245257502,1.5748140446524133,-0.6823322307636482,-0.5759332603866829,-0.29667029004619083,0.33978721059520445,-0.24785041714148484,-0.9898924303408787,0.4848802844441598,-0.15189356987392963,0.6251446041977697,0.10115585811536389,-0.4721974863524341,0.33978721059520445,-0.17567657782693433,0.27603929431054613,-0.5497550639890549,1.1088603313127976,0.5455653723813071,-0.22365336069552152,0.0108995245257502,-0.7365753446833382,0.4848802844441598,-0.27218882129392213,0.7225559645801342,-0.3709907348752914,-0.4721974863524341,-0.3709907348752914,2.3779621596515104,0.7417718580072862,0.21130916709284053
2,468
Generalized onset motor seizure
13
42
2.104026
0.035376
Q96N66,O60566,Q9Y3E5,Q01105,Q13510,P04062,P40763,P27635,P16278,O00429,P07602,Q9Y619,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
316,430,368,145,112,49,188,85,25,152,28,292,388
152,827,576,430,49,28,1445,25,720,85,1448,188,765,1055,2124,2416,1199,788,1132,145,2218,1384,864,112,1566,1489,748,884,1312,2286,2191,316,1612,2269,1213,1580,464,388,1082,368,2067,292
1.4952459017765753,0.18950873816397323,0.4644562459753665,0.6448072914475071,2.644481441197411,3.198719452250958,-0.24785041714148484,3.273996348775714,0.29739620791205207,2.0377346622172094,-0.24785041714148484,1.2980205320115141,0.2545732583950417,0.0108995245257502,-0.7915396678024824,-1.6840940352377014,-0.08134699713241711,0.2329969417200938,-0.03496930883195915,1.5431638652413855,-0.9037132041831669,-0.1995959661077008,0.16759443900767257,1.7750387384721054,-0.32129657210781537,-0.27218882129392213,0.27603929431054613,0.14556503368975818,-0.15189356987392963,-1.0190242872589113,-0.8753826232126409,0.8924386609086673,-0.34606944879987256,-0.9898924303408787,-0.08134699713241711,-0.32129657210781537,0.6251446041977697,0.7225559645801342,0.0108995245257502,0.7609008970028596,-0.7093648604789845,0.9658109974394301
2,468
Ion transport
9
46
2.101474
0.035599
Q93050,P21796,P45880,O96008,O75964,Q9Y277,Q9C0H2,P04920,Q9Y487
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
68,6,14,267,50,178,20,209,62
1700,2115,50,761,267,209,509,1707,1328,432,394,934,1446,2290,6,396,670,2441,936,1482,542,14,2424,2409,2047,810,1742,1058,1881,1687,290,1388,910,1391,68,1654,1351,1015,20,1016,1724,738,1081,178,1179,62
-0.4212859664531922,-0.7915396678024824,2.6073921114062215,0.2545732583950417,1.002027140929854,1.1786210307382605,0.5455653723813071,-0.4212859664531922,-0.17567657782693433,0.6448072914475071,0.7032523978558017,0.10115585811536389,-0.24785041714148484,-1.0483638394041492,4.254918317045912,0.7032523978558017,0.3608235263603773,-2.2752985103774694,0.10115585811536389,-0.27218882129392213,0.5052058365472561,3.796269049554577,-1.8240466439502927,-1.615882187826786,-0.7093648604789845,0.21130916709284053,-0.44666371637530605,0.0108995245257502,-0.5497550639890549,-0.3960622793653552,0.9658109974394301,-0.1995959661077008,0.12341926582388701,-0.1995959661077008,2.338517782432342,-0.3709907348752914,-0.17567657782693433,0.05627090662211817,3.4207949011245122,0.05627090662211817,-0.4212859664531922,0.29739620791205207,0.0108995245257502,1.3481865209735655,-0.058093817935866696,2.3779621596515104
2,468
Secretory granule
40
200
2.091534
0.03648
P45880,P42785,P30519,Q9UQB8,P14174,P07858,P16278,P07602,Q9NTK5,O00231,Q7L576,Q07065,P78310,Q99536,Q08380,P42892,P06280,Q8NF37,P10619,Q9Y487,P04066,P12956,Q93050,P15586,Q9H0U3,Q92542,O15121,O00584,Q9BTY2,Q9Y6I9,P09960,O75874,O00754,P06865,Q14974,Q13510,P09429,Q92820,Q9HBM0,Q9NZJ7
Localization
GO Cellular component
msigdb_gocc
14,17,21,22,280,24,25,28,291,284,298,295,294,311,308,56,187,315,61,62,189,321,68,207,335,339,86,342,100,369,103,104,231,232,238,112,357,376,377,388
1833,1439,284,1898,1182,1794,1440,342,231,86,631,1978,575,1475,522,1225,1587,760,896,985,104,2038,1798,2245,189,1836,782,187,783,1329,232,2206,1763,1265,28,1546,2071,24,1031,1189,1802,357,1591,103,1624,1906,494,418,61,2399,1960,930,1669,433,1032,1033,321,1190,1478,956,280,1735,1628,207,2040,25,1411,510,395,1736,1549,1871,1837,804,1232,1364,559,762,1447,703,2161,1767,498,1333,21,2120,1672,2164,541,1035,1236,2073,2466,2143,2291,542,1633,1195,1156,17,56,14,1416,684,1811,1038,742,1713,2123,726,511,1271,1129,1272,1056,2074,2125,1878,2168,1641,615,1642,1557,2019,616,1241,1426,294,743,1559,295,308,864,1244,2149,1307,1684,1064,1744,1564,1816,112,998,1885,966,1566,1747,238,706,384,1388,1168,599,2171,527,298,1528,1430,2027,1889,2315,315,970,339,376,68,425,1393,2455,2191,793,1281,311,817,2340,100,1317,974,1502,1016,335,714,377,1048,291,2087,388,1438,2065,1219,1698,1114,1699,921,22,1321,62,1760,1264,369
-0.5237411060737124,-0.24785041714148484,0.9658109974394301,-0.5759332603866829,-0.08134699713241711,-0.49788927155059765,-0.24785041714148484,0.7989016296808182,1.1088603313127976,2.023552801349019,0.4025832237568715,-0.6554750699704857,0.4644562459753665,-0.27218882129392213,0.5254338786156286,-0.10473033469147558,-0.34606944879987256,0.2545732583950417,0.12341926582388701,0.05627090662211817,1.8496309709719285,-0.7093648604789845,-0.49788927155059765,-0.9609652532252494,1.281166698194264,-0.5237411060737124,0.2329969417200938,1.2980205320115141,0.2329969417200938,-0.17567657782693433,1.1088603313127976,-0.9037132041831669,-0.4721974863524341,-0.1282453451374523,3.198719452250958,-0.32129657210781537,-0.7365753446833382,3.316440414035143,0.033646699417906,-0.08134699713241711,-0.49788927155059765,0.7609008970028596,-0.34606944879987256,1.8643955467119475,-0.3709907348752914,-0.5759332603866829,0.565601265268559,0.6643789100172187,2.3910310244631345,-1.5487932064905703,-0.6287910407099505,0.10115585811536389,-0.3960622793653552,0.6448072914475071,0.033646699417906,0.033646699417906,0.8738956173150244,-0.08134699713241711,-0.27218882129392213,0.07877351189206046,0.9839576617525956,-0.44666371637530605,-0.3709907348752914,1.1958841586688884,-0.7093648604789845,3.273996348775714,-0.22365336069552152,0.5455653723813071,0.7032523978558017,-0.44666371637530605,-0.32129657210781537,-0.5497550639890549,-0.5237411060737124,0.21130916709284053,-0.10473033469147558,-0.1995959661077008,0.4848802844441598,0.2545732583950417,-0.24785041714148484,0.3186451392955738,-0.8472453003312823,-0.4721974863524341,0.565601265268559,-0.17567657782693433,3.368926559380632,-0.7915396678024824,-0.3960622793653552,-0.8472453003312823,0.5052058365472561,0.033646699417906,-0.10473033469147558,-0.7365753446833382,-10.28916162859888,-0.8192985310386937,-1.0483638394041492,0.5052058365472561,-0.3709907348752914,-0.08134699713241711,-0.058093817935866696,3.5827914390839197,2.5069145047989934,3.796269049554577,-0.22365336069552152,0.33978721059520445,-0.49788927155059765,0.033646699417906,0.27603929431054613,-0.4212859664531922,-0.7915396678024824,0.29739620791205207,0.5455653723813071,-0.1282453451374523,-0.03496930883195915,-0.1282453451374523,0.0108995245257502,-0.7365753446833382,-0.7915396678024824,-0.5497550639890549,-0.8472453003312823,-0.3709907348752914,0.4233087298229898,-0.3709907348752914,-0.32129657210781537,-0.6823322307636482,0.4233087298229898,-0.10473033469147558,-0.22365336069552152,0.9475864635773026,0.27603929431054613,-0.32129657210781537,0.9475864635773026,0.9109010031706256,0.16759443900767257,-0.10473033469147558,-0.8192985310386937,-0.15189356987392963,-0.3960622793653552,0.0108995245257502,-0.44666371637530605,-0.32129657210781537,-0.49788927155059765,1.7750387384721054,0.05627090662211817,-0.5497550639890549,0.07877351189206046,-0.32129657210781537,-0.44666371637530605,1.0912400876291406,0.3186451392955738,0.7225559645801342,-0.1995959661077008,-0.058093817935866696,0.4439327299123976,-0.8472453003312823,0.5254338786156286,0.9475864635773026,-0.29667029004619083,-0.22365336069552152,-0.6823322307636482,-0.5497550639890549,-1.1076784324720763,0.8924386609086673,0.07877351189206046,0.8177749042593478,0.7417718580072862,2.338517782432342,0.6643789100172187,-0.1995959661077008,-2.7772284917892907,-0.8753826232126409,0.2329969417200938,-0.1282453451374523,0.9109010031706256,0.21130916709284053,-1.167861727972861,1.9083880241673503,-0.15189356987392963,0.07877351189206046,-0.27218882129392213,0.05627090662211817,0.8365644866172669,0.3186451392955738,0.7417718580072862,0.033646699417906,0.9658109974394301,-0.7365753446833382,0.7225559645801342,-0.22365336069552152,-0.7093648604789845,-0.08134699713241711,-0.3960622793653552,-0.011972007198974987,-0.3960622793653552,0.12341926582388701,3.368926559380632,-0.15189356987392963,2.3779621596515104,-0.44666371637530605,-0.10473033469147558,0.7609008970028596
2,468
Hydrolase
59
302
2.091198
0.03651
Q9H773,Q969T7,Q9UPY3,Q9H6V9,Q9BYT8,P42785,Q9UIQ6,P28072,O94919,P07858,P16278,O00429,Q9NTK5,Q9HB40,Q9H857,O14981,Q9H0C8,P50897,P11117,P28074,P29372,P04062,P50579,P42892,O75844,P52888,P06280,P10619,Q9UQ84,Q9H3G5,P04066,P12956,Q16740,Q5JRX3,Q9UPU5,P07099,O95336,P15586,Q86UV5,Q9NRZ9,Q7Z7L1,Q8IV08,Q96FW1,O60502,O00584,O14773,Q9HCE1,Q9BTY2,P09960,Q9Y3E5,O00754,P06865,Q9UMR5,P42575,P55786,Q96C86,Q13510,Q92820,Q9NPH0
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
0,2,259,8,275,17,19,268,278,24,25,152,291,34,164,285,300,39,167,42,301,49,52,56,185,58,187,61,64,65,189,321,67,196,198,199,332,207,338,348,219,92,220,95,342,94,229,100,103,368,231,232,108,236,110,361,112,376,251
2113,1323,1324,2448,825,152,1794,1440,342,1474,231,776,94,285,574,535,1028,2226,1475,557,982,2260,1835,779,95,802,1406,1730,698,1622,185,829,278,1666,1361,332,803,2158,2435,49,189,187,232,199,1763,1546,24,1031,1905,103,494,61,1363,167,1960,1090,1331,2208,321,1190,956,467,207,25,1670,395,784,933,1837,1671,680,1446,2072,991,652,993,1806,876,268,42,1983,1872,2368,1909,301,1333,1963,1839,835,764,1372,1334,541,2466,1675,2248,1594,1195,1932,2263,236,1512,17,56,996,671,1676,1297,1515,594,1770,937,1157,1677,52,39,1713,2123,1484,1419,58,1096,1636,1298,1420,1200,1201,2074,1057,110,1639,1640,2125,1454,1878,2168,1642,1557,2049,1845,420,2019,1425,1426,961,1988,1275,525,862,2078,1940,1685,112,685,1716,1817,965,705,398,747,1166,1002,1524,1717,512,1778,619,1102,687,707,67,635,421,196,2132,1277,1821,1822,2284,1573,750,1463,790,1574,219,2426,338,1991,92,1432,1918,1278,691,1349,1968,448,1530,2104,711,660,1209,751,2332,1495,1949,584,1993,449,2316,376,1107,2106,2056,604,570,472,2,712,361,220,1210,1951,2269,2058,793,1434,886,2059,1140,794,887,1723,100,2271,2467,2136,1396,275,1256,1257,300,1953,2193,1319,1284,2152,1216,65,850,571,1258,1077,8,0,164,1017,976,34,229,404,251,666,2335,1018,2256,1614,2195,378,348,474,291,517,2086,453,2239,1726,1861,1505,455,19,693,1542,2197,1583,108,759,1261,198,259,64,2199,2224,1473,1051,1543,630,368,477,2067,1083,2258,872
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2,468
Delusions
6
14
2.087704
0.036825
O00754,P49770,P04062,Q9BQE5,P07602,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
231,270,49,18,28,388
231,1475,49,28,651,1483,270,656,1818,18,428,388,1832,920
1.1088603313127976,-0.27218882129392213,2.644481441197411,3.198719452250958,0.3817551739233301,-0.27218882129392213,1.002027140929854,0.3817551739233301,-0.49788927155059765,3.5827914390839197,0.6643789100172187,0.7225559645801342,-0.49788927155059765,0.12341926582388701
2,468
Vascular neoplasm
7
30
2.085338
0.037039
P48735,Q15437,O75874,Q5H8A4,P21359,Q9UBM7,P10619
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
66,133,104,139,144,51,61
2140,104,761,1705,61,326,1446,144,720,2161,1448,723,2278,2391,1037,66,1677,1454,1845,841,962,218,133,139,447,1315,51,405,852,1792
-0.8192985310386937,1.8496309709719285,0.2545732583950417,-0.4212859664531922,2.3910310244631345,0.8552711400416021,-0.24785041714148484,1.5431638652413855,0.29739620791205207,-0.8472453003312823,-0.24785041714148484,0.29739620791205207,-1.0190242872589113,-1.4827895539405542,0.033646699417906,2.338517782432342,-0.3960622793653552,-0.24785041714148484,-0.5237411060737124,0.18950873816397323,0.07877351189206046,1.1438835156965523,1.6062322929490631,1.5748140446524133,0.6448072914475071,-0.15189356987392963,2.5949584998787207,0.7032523978558017,0.18950873816397323,-0.4721974863524341
2,468
Biliary tract abnormality
6
21
2.080342
0.037494
P04062,Q9UJW0,Q14108,P07602,Q96J02,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
49,215,87,28,228,63
1475,761,1705,2142,49,28,1668,280,1737,1675,2419,878,1063,87,63,944,570,228,1437,388,215
-0.27218882129392213,0.2545732583950417,-0.4212859664531922,-0.8192985310386937,2.644481441197411,3.198719452250958,-0.3960622793653552,0.9839576617525956,-0.44666371637530605,-0.3960622793653552,-1.7534682900989214,0.14556503368975818,0.0108995245257502,2.0093242006690732,2.364853829476893,0.10115585811536389,0.4848802844441598,1.1264079353050018,-0.22365336069552152,0.7225559645801342,1.1786210307382605
2,468
Flavin adenine dinucleotide binding
7
24
2.079167
0.037602
Q8NB78,P16435,Q14534,Q15392,P11310,O00116,Q16134
Functions
GO Molecular function
msigdb_gomf
7,326,296,47,175,123,31
521,123,2227,700,1798,1327,1591,175,2209,326,2094,1448,1965,296,400,47,31,1250,844,7,1578,1499,1613,1219
0.5254338786156286,1.6837858907333896,-0.9322398063664452,0.3186451392955738,-0.49788927155059765,-0.17567657782693433,-0.34606944879987256,1.3481865209735655,-0.9037132041831669,0.8552711400416021,-0.7639661184612422,-0.24785041714148484,-0.6287910407099505,0.9475864635773026,0.7032523978558017,2.705604207310635,3.0665949588136114,-0.10473033469147558,0.18950873816397323,4.186023680783169,-0.32129657210781537,-0.27218882129392213,-0.34606944879987256,-0.08134699713241711
2,468
Abnormal biliary tract morphology
6
19
2.074627
0.038021
P04062,Q9UJW0,Q14108,P07602,Q96J02,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
49,215,87,28,228,63
1475,2142,49,28,1668,280,1737,1675,2419,878,1063,87,63,944,570,228,1437,388,215
-0.27218882129392213,-0.8192985310386937,2.644481441197411,3.198719452250958,-0.3960622793653552,0.9839576617525956,-0.44666371637530605,-0.3960622793653552,-1.7534682900989214,0.14556503368975818,0.0108995245257502,2.0093242006690732,2.364853829476893,0.10115585811536389,0.4848802844441598,1.1264079353050018,-0.22365336069552152,0.7225559645801342,1.1786210307382605
2,468
Arthritis
11
33
2.072729
0.038198
P50851,O00170,P10321,P28070,Q13510,P04062,Q14108,P14174,O75844,P06280,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
225,349,418,457,112,49,87,280,185,187,63
349,185,1291,2142,49,187,1362,418,903,280,651,858,457,936,594,225,2409,1097,1039,1057,2348,1275,112,87,63,1567,1348,1072,947,2086,1505,1792,477
0.7799438888928811,1.3148080906459898,-0.15189356987392963,-0.8192985310386937,2.644481441197411,1.2980205320115141,-0.1995959661077008,0.6643789100172187,0.12341926582388701,0.9839576617525956,0.3817551739233301,0.16759443900767257,0.6251446041977697,0.10115585811536389,0.4439327299123976,1.1264079353050018,-1.615882187826786,-0.011972007198974987,0.033646699417906,0.0108995245257502,-1.1982874368625742,-0.1282453451374523,1.7750387384721054,2.0093242006690732,2.364853829476893,-0.32129657210781537,-0.17567657782693433,0.0108995245257502,0.10115585811536389,-0.7365753446833382,-0.27218882129392213,-0.4721974863524341,0.6053899682620425
2,468
Organic hydroxy compound metabolic process
17
85
2.072217
0.038245
Q8WTV0,P48735,O76062,O15269,O75874,Q9NPH2,Q6NUM9,Q15392,Q13510,P04062,Q9BQE5,Q9UBM7,Q15800,P00374,P07858,Q16850,Q14739
Processes and pathways
GO Biological process
msigdb_gobp
36,66,102,223,104,168,239,47,112,49,18,51,114,279,24,121,63
2113,696,223,2138,2114,855,104,102,2345,1589,279,1798,1291,49,1799,986,2116,24,2458,1627,496,2181,1928,326,1907,651,805,2182,1838,860,1191,2095,995,1296,1193,1512,1269,1197,66,1965,2279,1934,837,2124,441,1129,1772,383,1453,2216,1879,1339,1680,1275,1063,112,1884,296,63,2370,47,2437,114,2129,121,239,2104,1531,1890,36,362,2057,1108,1434,2178,2365,18,168,1018,51,775,1219,1261,2440,824
-0.7915396678024824,0.3186451392955738,1.1264079353050018,-0.8192985310386937,-0.7915396678024824,0.16759443900767257,1.8496309709719285,1.8643955467119475,-1.1982874368625742,-0.34606944879987256,0.9839576617525956,-0.49788927155059765,-0.15189356987392963,2.644481441197411,-0.49788927155059765,0.05627090662211817,-0.7915396678024824,3.316440414035143,-3.001354480809533,-0.3709907348752914,0.565601265268559,-0.8753826232126409,-0.6022778524744863,0.8552711400416021,-0.5759332603866829,0.3817551739233301,0.21130916709284053,-0.8753826232126409,-0.5237411060737124,0.16759443900767257,-0.08134699713241711,-0.7639661184612422,0.05627090662211817,-0.15189356987392963,-0.08134699713241711,-0.29667029004619083,-0.1282453451374523,-0.08134699713241711,2.338517782432342,-0.6287910407099505,-1.0190242872589113,-0.6022778524744863,0.18950873816397323,-0.7915396678024824,0.6448072914475071,-0.03496930883195915,-0.4721974863524341,0.7225559645801342,-0.24785041714148484,-0.9037132041831669,-0.5497550639890549,-0.17567657782693433,-0.3960622793653552,-0.1282453451374523,0.0108995245257502,1.7750387384721054,-0.5497550639890549,0.9475864635773026,2.364853829476893,-1.322298943353699,2.705604207310635,-2.15778072649351,1.7448358781713682,-0.7915396678024824,1.6991299075669488,1.0912400876291406,-0.7639661184612422,-0.29667029004619083,-0.5497550639890549,2.8839991952794084,0.7609008970028596,-0.7093648604789845,-0.011972007198974987,-0.22365336069552152,-0.8472453003312823,-1.290942522796084,3.5827914390839197,1.3977702991328884,0.05627090662211817,2.5949584998787207,0.2545732583950417,-0.08134699713241711,-0.10473033469147558,-2.235771034953379,0.21130916709284053
2,468
Entry into host
6
27
2.070425
0.038413
Q8WTV0,Q9BTY2,P19474,Q14108,P07858,Q96J02
Processes and pathways
GO Biological process
msigdb_gobp
36,100,46,87,24,228
1955,696,2068,591,1800,1030,1545,24,1801,1803,1906,1669,467,46,1154,2213,1236,1712,294,87,598,1136,36,1532,228,100,489
-0.6287910407099505,0.3186451392955738,-0.7365753446833382,0.4439327299123976,-0.49788927155059765,0.033646699417906,-0.32129657210781537,3.316440414035143,-0.49788927155059765,-0.49788927155059765,-0.5759332603866829,-0.3960622793653552,0.6053899682620425,2.705604207310635,-0.058093817935866696,-0.9037132041831669,-0.10473033469147558,-0.4212859664531922,0.9475864635773026,2.0093242006690732,0.4439327299123976,-0.03496930883195915,2.8839991952794084,-0.29667029004619083,1.1264079353050018,1.9083880241673503,0.5855424906777212
2,468
Carbohydrate derivative transport
7
12
2.065687
0.038858
Q99808,Q8WTV0,P07602,P12235,Q8TB61,Q9HC21,Q9NZJ7
Processes and pathways
GO Biological process
msigdb_gobp
387,36,28,558,118,515,388
1181,556,1590,28,558,931,1526,118,36,387,515,388
-0.08134699713241711,0.4848802844441598,-0.34606944879987256,3.198719452250958,0.4848802844441598,0.10115585811536389,-0.29667029004619083,1.7296545033561892,2.8839991952794084,0.7225559645801342,0.5455653723813071,0.7225559645801342
2,468
Zinc ion binding
22
108
2.062032
0.039205
Q8N4Q0,Q15437,Q8NB78,Q14527,Q9UIQ6,O15344,Q9NUD5,P29372,P19474,Q99536,P42892,Q5JRX3,P34896,Q5JPH6,O75151,Q15436,Q9NWV4,Q86WB0,P09960,Q14974,P55786,Q9NRW3
Functions
GO Molecular function
msigdb_gomf
1,133,7,398,19,391,417,301,46,311,56,196,76,82,217,218,355,99,103,238,110,378
1326,391,697,217,927,829,2204,1732,1477,1086,856,1734,2435,537,1799,832,1547,1088,103,1627,467,784,46,859,834,957,876,2161,301,1370,76,836,2390,1483,56,611,996,1595,1237,1336,1812,1039,1298,110,938,1202,2147,1939,862,1385,1745,1487,398,1717,1748,238,1777,1915,218,133,1387,2354,1946,82,196,1569,1168,1781,769,2173,1649,99,1826,642,1,2423,7,711,1785,2056,1011,1994,1786,1970,2135,311,817,887,426,850,1047,977,378,417,355,1505,552,1020,1113,1660,19,1924,2198,1728,477,2067,648,872
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2,468
Peptide binding
11
57
2.057618
0.039627
O14773,Q8TEX9,P24390,Q8WTV0,Q14974,P55786,Q15392,Q92973,Q9UIQ6,P42892,Q03519
Functions
GO Molecular function
msigdb_gomf
94,227,3,36,238,110,47,116,19,56,246
1182,319,1955,695,94,1664,697,718,1507,900,1189,2207,418,467,1737,2358,3,2161,2347,1873,1155,1192,2291,592,56,2044,1712,1198,1128,370,1096,110,1454,2348,1059,2145,246,1242,1686,1989,238,2401,731,47,227,36,116,2286,752,1657,275,2110,1400,1505,476,19,1866
-0.08134699713241711,0.8738956173150244,-0.6287910407099505,0.3186451392955738,1.9374688026168079,-0.3960622793653552,0.3186451392955738,0.29739620791205207,-0.29667029004619083,0.12341926582388701,-0.08134699713241711,-0.9037132041831669,0.6643789100172187,0.6053899682620425,-0.44666371637530605,-1.2598242554926813,4.4061529638753205,-0.8472453003312823,-1.1982874368625742,-0.5497550639890549,-0.058093817935866696,-0.08134699713241711,-1.0483638394041492,0.4439327299123976,2.5069145047989934,-0.7093648604789845,-0.4212859664531922,-0.08134699713241711,-0.03496930883195915,0.7417718580072862,-0.011972007198974987,1.7900609938314576,-0.24785041714148484,-1.1982874368625742,0.0108995245257502,-0.8192985310386937,1.0557791765577014,-0.10473033469147558,-0.3960622793653552,-0.6554750699704857,1.0912400876291406,-1.5487932064905703,0.29739620791205207,2.705604207310635,1.1264079353050018,2.8839991952794084,1.7448358781713682,-1.0190242872589113,0.27603929431054613,-0.3709907348752914,1.002027140929854,-0.7639661184612422,-0.1995959661077008,-0.27218882129392213,0.6053899682620425,3.542845976168228,-0.5237411060737124
2,468
Macromolecule catabolic process
78
329
2.057594
0.039629
Q9NUJ1,Q969T7,P51665,Q6ZXV5,Q9UNN5,O75150,Q8N511,Q9UIQ6,P07858,P16278,P49721,O75503,P50897,P28074,Q9UHG3,P04062,P10619,Q16740,P51114,P51116,Q9UBU6,O60502,O14773,A0AVT1,Q16850,Q92804,A4D1P6,Q92945,O75844,P04066,Q9UPU5,P15586,Q96J02,Q9HCE1,P24941,Q6PGP7,Q9Y5A7,Q9H270,Q9UPY3,Q99816,Q9GZP4,Q16763,Q9BUN8,P46379,P28072,O00231,Q96F86,Q8NF37,Q8N668,Q00535,O14964,P49427,Q86UV5,O00584,Q92615,Q96KB5,Q9Y263,Q96EB6,Q96C86,Q14011,Q13618,Q9UJX3,Q9H074,Q9H2J4,Q96CS3,Q92990,Q8N3C0,Q5VTR2,P98175,P28070,Q93009,P14735,Q9UJX4,Q9UL15,P60900,P49720,P10253,Q9UBV2
Processes and pathways
GO Biological process
msigdb_gobp
517,2,511,528,534,12,16,19,24,25,26,32,39,42,44,49,61,67,88,89,90,95,94,109,121,156,174,181,185,189,198,207,228,229,224,242,253,257,259,264,265,261,274,269,268,284,299,315,314,328,330,333,338,342,353,363,366,362,361,373,372,406,416,427,425,423,448,445,442,457,472,467,488,507,501,500,494,518
109,174,1084,1024,284,1183,1794,342,94,1796,330,1403,1326,799,826,2156,575,717,924,557,2068,95,649,1618,2140,1619,12,927,1406,1925,2114,32,1150,698,699,185,2204,1958,856,803,700,49,189,1409,783,2324,2206,1763,24,1031,2376,1362,1189,1087,1330,1906,494,61,1960,930,1961,1962,1266,467,988,1764,207,25,1411,1670,1736,784,804,559,1480,858,1154,224,1332,1447,1511,1929,1805,1806,2161,1710,1767,457,268,42,1371,1674,2213,2042,541,561,2073,1675,2248,1594,1932,1037,1373,2144,996,269,1676,1876,2419,1418,593,333,500,26,2250,704,39,88,89,2123,1375,511,1935,1420,1637,1200,1379,2074,838,1638,501,2184,1422,904,2229,2049,1845,1381,1814,1060,2230,1130,2313,2050,545,879,787,1061,442,328,2302,1988,2218,1384,906,2078,744,1303,2052,1562,1563,730,1064,1744,1308,1487,1816,2233,2099,372,1165,1746,373,746,598,2023,675,1002,1990,706,1343,1004,1428,2188,865,2080,687,1205,1068,67,261,121,1886,2131,1168,2132,445,1606,1251,1277,1207,638,242,1429,968,1572,528,1573,710,640,1649,1528,2189,338,2220,547,642,1349,1968,1103,448,16,314,1851,315,912,845,2332,1495,603,1651,1652,353,156,1072,2056,2379,181,423,570,472,1044,2,2445,816,361,425,362,299,947,228,644,363,2057,1970,2058,793,1281,2135,1434,1109,886,848,264,1140,794,887,1283,1468,274,1075,678,265,1502,416,1953,692,257,427,1284,891,1017,229,977,666,1975,588,517,1286,1863,1019,1830,949,1541,667,2436,90,518,44,19,533,406,488,1354,1220,507,758,628,2111,759,1699,534,629,198,259,1864,366,1051,2036,1115,1116,648,253,1083,1897,1290,2112,1793,2258
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2,468
Abnormality of the amniotic fluid
17
70
2.057371
0.039651
P40939,Q8TD19,Q70HW3,P16435,P49366,Q9BT22,P23786,Q9UHX1,P04062,Q6PGP7,Q9UBM7,P27635,Q7LGA3,P51114,O75844,Q7LBC6,Q14739
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
33,385,40,326,138,140,293,405,49,242,51,85,447,88,185,412,63
827,1358,430,1620,185,2142,49,1959,538,1628,2040,326,1446,651,1154,293,993,85,1675,1414,2388,33,1911,765,138,1055,1677,88,878,2409,1842,1039,2167,1845,1161,2050,2301,1683,1716,63,1688,1914,767,690,1526,1347,242,40,412,447,969,385,1072,1350,2135,605,140,1213,1437,572,796,51,405,1081,1114,852,1320,922,2243,824
0.18950873816397323,-0.1995959661077008,0.6448072914475071,-0.3709907348752914,1.3148080906459898,-0.8192985310386937,2.644481441197411,-0.6287910407099505,0.5052058365472561,-0.3709907348752914,-0.7093648604789845,0.8552711400416021,-0.24785041714148484,0.3817551739233301,-0.058093817935866696,0.9475864635773026,0.05627090662211817,2.0377346622172094,-0.3960622793653552,-0.22365336069552152,-1.4501835103812906,2.9876441146417414,-0.5759332603866829,0.2545732583950417,1.5748140446524133,0.0108995245257502,-0.3960622793653552,1.9950485407418646,0.14556503368975818,-1.615882187826786,-0.5237411060737124,0.033646699417906,-0.8472453003312823,-0.5237411060737124,-0.058093817935866696,-0.7093648604789845,-1.0779141700680717,-0.3960622793653552,-0.4212859664531922,2.364853829476893,-0.3960622793653552,-0.5759332603866829,0.2545732583950417,0.33978721059520445,-0.29667029004619083,-0.17567657782693433,1.073546580138068,2.7897625739952723,0.6838603272070093,0.6448072914475071,0.07877351189206046,0.7225559645801342,0.0108995245257502,-0.17567657782693433,-0.7915396678024824,0.4439327299123976,1.5748140446524133,-0.08134699713241711,-0.22365336069552152,0.4848802844441598,0.2329969417200938,2.5949584998787207,0.7032523978558017,0.0108995245257502,-0.011972007198974987,0.18950873816397323,-0.15189356987392963,0.12341926582388701,-0.9322398063664452,0.21130916709284053
2,468
Dysphagia
25
104
2.055717
0.03981
Q9UBB4,Q15067,Q01105,Q9UHX1,P21359,O00429,O75569,P07602,P29372,P04062,P63241,O95169,Q14739,Q8IZA0,P48735,Q99720,P15586,Q14108,O75874,Q9Y263,P54136,Q13510,Q69YQ0,Q8N0X7,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
258,400,145,405,144,152,277,28,301,49,306,305,63,323,66,80,207,87,104,366,105,112,241,249,388
152,2337,853,696,391,1120,779,896,984,1957,277,104,1228,305,2179,1291,49,1231,538,28,1444,832,1625,987,558,207,1479,1982,2415,144,720,740,2367,301,1984,1448,561,936,723,499,1373,611,66,2124,1842,105,612,810,2074,1057,1715,1421,306,1600,1132,145,1202,963,2218,1384,964,864,1562,112,87,583,1566,1489,63,400,1914,1247,812,241,1916,1572,2371,323,249,1919,1010,1578,2191,2057,1315,2135,2178,80,2085,1213,1973,2110,1580,464,388,258,1895,821,2318,405,1262,366,952,2067
1.4952459017765753,-1.167861727972861,0.16759443900767257,0.3186451392955738,0.7032523978558017,-0.03496930883195915,0.2329969417200938,0.12341926582388701,0.05627090662211817,-0.6287910407099505,0.9839576617525956,1.8496309709719285,-0.10473033469147558,0.9109010031706256,-0.8753826232126409,-0.15189356987392963,2.644481441197411,-0.10473033469147558,0.5052058365472561,3.198719452250958,-0.24785041714148484,0.18950873816397323,-0.3709907348752914,0.05627090662211817,0.4848802844441598,1.1958841586688884,-0.27218882129392213,-0.6554750699704857,-1.6840940352377014,1.5431638652413855,0.29739620791205207,0.27603929431054613,-1.322298943353699,0.9292833665100879,-0.6554750699704857,-0.24785041714148484,0.4848802844441598,0.10115585811536389,0.29739620791205207,0.565601265268559,-0.1995959661077008,0.4233087298229898,2.338517782432342,-0.7915396678024824,-0.5237411060737124,1.834815592336478,0.4233087298229898,0.21130916709284053,-0.7365753446833382,0.0108995245257502,-0.4212859664531922,-0.22365336069552152,0.9109010031706256,-0.34606944879987256,-0.03496930883195915,1.5431638652413855,-0.08134699713241711,0.07877351189206046,-0.9037132041831669,-0.1995959661077008,0.07877351189206046,0.16759443900767257,-0.32129657210781537,1.7750387384721054,2.0093242006690732,0.4644562459753665,-0.32129657210781537,-0.27218882129392213,2.364853829476893,0.7032523978558017,-0.5759332603866829,-0.10473033469147558,0.21130916709284053,1.073546580138068,-0.5759332603866829,-0.32129657210781537,-1.322298943353699,0.8738956173150244,1.0557791765577014,-0.5759332603866829,0.05627090662211817,-0.32129657210781537,-0.8753826232126409,-0.7093648604789845,-0.15189356987392963,-0.7915396678024824,-0.8472453003312823,2.13572512937309,-0.7365753446833382,-0.08134699713241711,-0.6287910407099505,-0.7639661184612422,-0.32129657210781537,0.6251446041977697,0.7225559645801342,1.0379372362963877,-0.5497550639890549,0.21130916709284053,-1.1076784324720763,0.7032523978558017,-0.10473033469147558,0.7609008970028596,0.10115585811536389,-0.7093648604789845
2,468
Abnormal cellular phenotype
29
147
2.050982
0.040269
Q9UBX3,Q15437,Q9Y2R0,P14174,O00429,P07602,Q16134,O75503,P40939,Q15904,Q70HW3,O43676,P11310,P04062,O75844,P40763,Q14739,O43772,P15586,Q5JPH6,Q9UJW0,Q14108,Q96J02,O14773,P50851,O00754,Q13510,Q6PGP7,Q9Y6M9
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
134,133,142,280,152,28,31,32,33,290,40,45,175,49,185,188,63,77,207,82,215,87,228,94,225,231,112,242,254
798,152,1834,231,94,45,77,430,2228,2373,984,1957,32,985,185,1360,1229,803,410,2322,2245,2435,2142,591,49,1799,28,2261,1668,1591,1804,1445,1626,2247,175,903,558,2208,857,2209,280,207,2040,497,933,1982,2160,1671,2093,1737,1480,720,651,1838,293,1805,834,957,457,2367,1909,2212,1448,764,561,2299,188,33,1037,1373,1374,2419,594,1965,1516,1157,225,2124,2409,1985,1337,1039,1298,2017,2074,1715,1600,1163,1275,905,2425,1562,112,1716,87,63,748,2370,133,687,767,290,31,812,351,636,421,82,690,1821,242,40,1348,1650,2332,449,2106,1072,1170,1312,1012,712,1694,228,1046,1695,2135,2178,335,1613,464,516,348,572,388,475,2240,134,920,215,1179,142,1759,1954,2067,1290,254
0.21130916709284053,1.4952459017765753,-0.5237411060737124,1.1088603313127976,1.9374688026168079,2.7177266378332408,2.1907384712256417,0.6448072914475071,-0.9322398063664452,-1.3538973144414643,0.05627090662211817,-0.6287910407099505,3.010346969899404,0.05627090662211817,1.3148080906459898,-0.1995959661077008,-0.10473033469147558,0.21130916709284053,0.6838603272070093,-1.137659851909859,-0.9609652532252494,-2.119318322676024,-0.8192985310386937,0.4439327299123976,2.644481441197411,-0.49788927155059765,3.198719452250958,-0.9898924303408787,-0.3960622793653552,-0.34606944879987256,-0.49788927155059765,-0.24785041714148484,-0.3709907348752914,-0.9609652532252494,1.3481865209735655,0.12341926582388701,0.4848802844441598,-0.9037132041831669,0.16759443900767257,-0.9037132041831669,0.9839576617525956,1.1958841586688884,-0.7093648604789845,0.565601265268559,0.10115585811536389,-0.6554750699704857,-0.8472453003312823,-0.3960622793653552,-0.7639661184612422,-0.44666371637530605,-0.27218882129392213,0.29739620791205207,0.3817551739233301,-0.5237411060737124,0.9475864635773026,-0.49788927155059765,0.18950873816397323,0.07877351189206046,0.6251446041977697,-1.322298943353699,-0.5759332603866829,-0.9037132041831669,-0.24785041714148484,0.2545732583950417,0.4848802844441598,-1.0779141700680717,1.2980205320115141,2.9876441146417414,0.033646699417906,-0.1995959661077008,-0.1995959661077008,-1.7534682900989214,0.4439327299123976,-0.6287910407099505,-0.29667029004619083,-0.058093817935866696,1.1264079353050018,-0.7915396678024824,-1.615882187826786,-0.6554750699704857,-0.17567657782693433,0.033646699417906,-0.15189356987392963,-0.6823322307636482,-0.7365753446833382,-0.4212859664531922,-0.34606944879987256,-0.058093817935866696,-0.1282453451374523,0.12341926582388701,-1.859801013532104,-0.32129657210781537,1.7750387384721054,-0.4212859664531922,2.0093242006690732,2.364853829476893,0.27603929431054613,-1.322298943353699,1.6062322929490631,0.33978721059520445,0.2545732583950417,0.9658109974394301,3.0665949588136114,0.21130916709284053,0.7799438888928811,0.4025832237568715,0.6643789100172187,2.0800029514374274,0.33978721059520445,-0.49788927155059765,1.073546580138068,2.7897625739952723,-0.17567657782693433,-0.3709907348752914,-1.137659851909859,0.6448072914475071,-0.7639661184612422,0.0108995245257502,-0.058093817935866696,-0.15189356987392963,0.05627090662211817,0.3186451392955738,-0.3960622793653552,1.1264079353050018,0.033646699417906,-0.3960622793653552,-0.7915396678024824,-0.8472453003312823,0.8365644866172669,-0.34606944879987256,0.6251446041977697,0.5455653723813071,0.7989016296808182,0.4848802844441598,0.7225559645801342,0.6053899682620425,-0.9322398063664452,1.6062322929490631,0.12341926582388701,1.1786210307382605,-0.058093817935866696,1.5590181672791275,-0.44666371637530605,-0.6022778524744863,-0.7093648604789845,-0.1282453451374523,1.0557791765577014
2,468
cysteine protease
7
15
2.028314
0.042528
Q9UPU5,Q13510,Q92820,Q86UV5,Q93009,P07858,Q96FW1
Functions
Panther Protein class
panther_protein_class
198,112,376,338,472,24,220
1763,24,996,1420,112,965,1002,1946,338,376,570,472,220,198,1083
-0.4721974863524341,3.316440414035143,0.05627090662211817,-0.22365336069552152,1.7750387384721054,0.07877351189206046,0.05627090662211817,-0.6022778524744863,0.8177749042593478,0.7417718580072862,0.4848802844441598,0.6053899682620425,1.1438835156965523,1.2472580264373727,0.0108995245257502
2,468
Ligase
35
63
4.229808
0.000023
P26640,P07814,A0AVT1,P27708,P50747,P14868,P49916,Q13085,P11498,Q9Y3I0,Q9BW92,Q5JPH6,Q9Y285,Q96RQ3,O60488,P49588,P30520,P08243,P49591,Q9NSD9,P05165,Q9P2J5,P23381,P49915,P22102,P26639,Q15046,P53597,Q9HA77,Q9NP81,P22314,O43776,P48506,P54136,O00763
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
127,126,5,501,15,389,635,17,18,555,552,28,702,34,532,538,679,294,44,459,52,462,435,189,564,436,347,443,99,618,335,91,237,599,116
5,116,1005,91,532,709,52,2267,126,294,18,389,675,564,1559,335,435,436,127,501,679,1268,1270,719,832,237,1354,538,1058,44,189,635,15,443,599,1018,835,17,795,932,347,28,1616,1533,1408,1242,1163,1698,852,34,552,99,810,618,459,1424,462,1854,777,1632,702,2068,555
4.637142878618707,1.5148945458722094,0.16429650233449708,1.6329179826648552,0.5830937941090167,0.40657274055962805,2.1205507147690597,-1.1877628050053848,1.4758764855204225,0.9454541305169961,2.9517648784557937,0.762668016319278,0.44163988227236045,0.5475501784669402,-0.2717409991326573,0.8353876893846488,0.690462087882705,0.690462087882705,1.4758764855204225,0.6187594963253328,0.44163988227236045,-0.03911004514660509,-0.03911004514660509,0.40657274055962805,0.30206435300525497,1.09411123321543,-0.106077830470184,0.5830937941090167,0.13012911860860088,2.2044216937819225,1.2070828107445577,0.4768243999762741,3.231128956611099,0.690462087882705,0.5121274427616084,0.16429650233449708,0.30206435300525497,3.090438391144676,0.33678607999499527,0.23295871445948424,0.8353876893846488,2.592032399318675,-0.3045794640677411,-0.23880560493110126,-0.1394094247514785,-0.005472043382106115,0.06211680648946061,-0.36996889215618123,0.30206435300525497,2.4609050013050613,0.5830937941090167,1.6329179826648552,0.33678607999499527,0.5121274427616084,0.690462087882705,-0.1394094247514785,0.690462087882705,-0.49962010917283683,0.3716218440786248,-0.3045794640677411,0.44163988227236045,-0.7545819832932289,0.5830937941090167
2,466
Helicase, C-terminal [IPR001650]
22
61
3.768772
0.000164
P54132,Q9Y2R4,O14981,P19447,Q9HCK8,Q8IY37,Q14562,Q8TDD1,Q9GZR7,Q14839,Q7L014,Q92499,P51532,Q14527,Q9UPY3,Q9H2U1,O14646,Q92620,P46063,Q9NRZ9,Q13206,O60231
Sequence
InterPro Domain
interpro_domain
400,412,7,256,152,23,287,299,455,312,57,58,308,194,66,328,71,485,339,379,512,230
703,1216,71,7,1433,230,821,867,1263,256,565,1227,2125,1193,339,308,400,1730,1065,512,1570,1022,194,287,312,642,1695,1076,57,686,1317,988,798,23,610,799,2081,1320,299,58,485,1246,523,895,1031,1081,455,1707,328,2029,1888,152,655,379,948,1543,1212,1291,66,412,1674
0.40657274055962805,-0.005472043382106115,1.7926187250454313,3.963965887756176,-0.17264067204748582,1.09411123321543,0.30206435300525497,0.26745558495361116,-0.03911004514660509,1.0195061138420503,0.5475501784669402,-0.005472043382106115,-0.8799840708301513,0.02826992735684619,0.8353876893846488,0.9086318760961686,0.762668016319278,-0.4025214696779287,0.13012911860860088,0.6187594963253328,-0.2717409991326573,0.16429650233449708,1.2070828107445577,0.9824117244906789,0.9086318760961686,0.4768243999762741,-0.36996889215618123,0.13012911860860088,2.037454957685927,0.44163988227236045,-0.0726450035074068,0.19857269655533746,0.33678607999499527,2.8151353625654076,0.5121274427616084,0.33678607999499527,-0.786059355940462,-0.0726450035074068,0.9454541305169961,1.9961913574668617,0.6545485118299024,-0.005472043382106115,0.6187594963253328,0.26745558495361116,0.16429650233449708,0.13012911860860088,0.690462087882705,-0.36996889215618123,0.8719435308811879,-0.691369514566026,-0.5318025210216746,1.3597650907486145,0.4768243999762741,0.7989629703796846,0.23295871445948424,-0.23880560493110126,0.02826992735684619,-0.03911004514660509,1.8735081335636863,0.762668016319278,-0.33732182412727213
2,466
Helicase superfamily 1/2, ATP-binding domain [IPR014001]
22
60
3.751986
0.000175
P54132,Q9Y2R4,O14981,P19447,Q9HCK8,Q8IY37,Q14562,Q8TDD1,Q9GZR7,Q14839,Q7L014,Q92499,P51532,Q14527,Q9UPY3,Q9H2U1,O14646,Q92620,P46063,Q9NRZ9,Q13206,O60231
Sequence
InterPro Domain
interpro_domain
400,412,7,256,152,23,287,299,455,312,57,58,308,194,66,328,71,485,339,379,512,230
703,1216,71,7,1433,230,821,867,1263,256,565,1227,2125,1193,339,308,400,1730,1065,512,1570,1022,194,287,312,642,1695,1076,57,686,1317,988,798,23,799,2081,1320,299,58,485,1246,523,895,1031,1081,455,1707,328,2029,1888,152,655,379,948,1543,1212,1291,66,412,1674
0.40657274055962805,-0.005472043382106115,1.7926187250454313,3.963965887756176,-0.17264067204748582,1.09411123321543,0.30206435300525497,0.26745558495361116,-0.03911004514660509,1.0195061138420503,0.5475501784669402,-0.005472043382106115,-0.8799840708301513,0.02826992735684619,0.8353876893846488,0.9086318760961686,0.762668016319278,-0.4025214696779287,0.13012911860860088,0.6187594963253328,-0.2717409991326573,0.16429650233449708,1.2070828107445577,0.9824117244906789,0.9086318760961686,0.4768243999762741,-0.36996889215618123,0.13012911860860088,2.037454957685927,0.44163988227236045,-0.0726450035074068,0.19857269655533746,0.33678607999499527,2.8151353625654076,0.33678607999499527,-0.786059355940462,-0.0726450035074068,0.9454541305169961,1.9961913574668617,0.6545485118299024,-0.005472043382106115,0.6187594963253328,0.26745558495361116,0.16429650233449708,0.13012911860860088,0.690462087882705,-0.36996889215618123,0.8719435308811879,-0.691369514566026,-0.5318025210216746,1.3597650907486145,0.4768243999762741,0.7989629703796846,0.23295871445948424,-0.23880560493110126,0.02826992735684619,-0.03911004514660509,1.8735081335636863,0.762668016319278,-0.33732182412727213
2,466
Hematological neoplasm
26
64
3.644157
0.000268
Q07864,P54132,Q7Z2Z2,O76094,P61313,P08708,Q9NVI1,O60934,P42766,Q9H0U3,P40763,P18077,P22681,P33991,P50851,P60866,Q08J23,P21359,Q07020,P00813,P22314,Q06124,P52701,P62899,P49327,P35658
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
130,400,268,254,19,281,158,278,419,42,295,160,51,175,56,310,447,80,343,333,335,474,101,109,245,366
1132,1434,626,278,469,254,1638,1789,333,1598,1639,1599,281,628,675,160,80,335,51,1723,175,366,1351,1606,295,419,1148,754,1231,245,56,101,921,400,570,310,509,923,19,1397,1452,756,1102,837,2146,109,1873,1493,474,343,130,447,1765,762,1362,268,1920,42,2357,158,812,1291,1822,1592
0.06211680648946061,-0.17264067204748582,0.4768243999762741,0.9824117244906789,0.6545485118299024,1.0195061138420503,-0.33732182412727213,-0.46734630399467275,0.8353876893846488,-0.3045794640677411,-0.33732182412727213,-0.3045794640677411,0.9824117244906789,0.4768243999762741,0.44163988227236045,1.2831250541224368,1.752437029840453,0.8353876893846488,2.162387986697736,-0.4025214696779287,1.2450300545136346,0.7989629703796846,-0.106077830470184,-0.3045794640677411,0.9454541305169961,0.7265014927733182,0.06211680648946061,0.3716218440786248,-0.005472043382106115,1.0567387805118416,2.0789072337159866,1.5934133472710452,0.23295871445948424,0.762668016319278,0.5475501784669402,0.9086318760961686,0.6187594963253328,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.17264067204748582,0.3716218440786248,0.09606954757438466,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,-0.20577244529591113,0.6545485118299024,0.8353876893846488,1.4758764855204225,0.690462087882705,-0.4349803471134479,0.3716218440786248,-0.106077830470184,1.0195061138420503,-0.5638942876356867,2.289089293908105,-1.517439986141119,1.3213694940336442,0.33678607999499527,-0.03911004514660509,-0.46734630399467275,-0.2717409991326573
2,466
Helicase
37
76
3.570406
0.000356
P54132,Q15477,Q9Y2R4,O14981,P19447,Q9HCK8,Q92900,Q8IY37,Q14562,Q7Z7L1,P49736,Q8TDD1,Q9GZR7,P33993,P33991,Q14839,Q7L014,Q92499,P51532,Q14527,Q9UPY3,Q9H2U1,P25205,P13010,P26196,O14646,Q8IYB8,Q92620,Q13283,Q9HCE1,P46063,P33992,P18074,Q9NRZ9,Q13206,O60231,Q9NR30
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
400,642,412,7,256,152,690,23,287,156,282,299,455,176,175,312,57,58,308,194,66,328,186,433,565,71,610,485,345,617,339,338,594,379,512,230,655
703,1216,71,7,1433,230,821,1258,867,1445,433,1263,594,256,186,565,1227,175,338,176,2125,1193,339,282,308,400,1730,1065,512,345,1570,1022,194,287,882,312,642,1695,1076,57,686,1317,156,988,798,23,610,799,2081,1320,299,58,485,1246,690,895,1031,1081,455,1707,328,2029,1888,617,152,655,379,948,1543,1212,1291,66,1927,1820,412,1674
0.40657274055962805,-0.005472043382106115,1.7926187250454313,3.963965887756176,-0.17264067204748582,1.09411123321543,0.30206435300525497,-0.03911004514660509,0.26745558495361116,-0.17264067204748582,0.690462087882705,-0.03911004514660509,0.5121274427616084,1.0195061138420503,1.2070828107445577,0.5475501784669402,-0.005472043382106115,1.2450300545136346,0.8353876893846488,1.2450300545136346,-0.8799840708301513,0.02826992735684619,0.8353876893846488,0.9824117244906789,0.9086318760961686,0.762668016319278,-0.4025214696779287,0.13012911860860088,0.6187594963253328,0.8353876893846488,-0.2717409991326573,0.16429650233449708,1.2070828107445577,0.9824117244906789,0.26745558495361116,0.9086318760961686,0.4768243999762741,-0.36996889215618123,0.13012911860860088,2.037454957685927,0.44163988227236045,-0.0726450035074068,1.3213694940336442,0.19857269655533746,0.33678607999499527,2.8151353625654076,0.5121274427616084,0.33678607999499527,-0.786059355940462,-0.0726450035074068,0.9454541305169961,1.9961913574668617,0.6545485118299024,-0.005472043382106115,0.44163988227236045,0.26745558495361116,0.16429650233449708,0.13012911860860088,0.690462087882705,-0.36996889215618123,0.8719435308811879,-0.691369514566026,-0.5318025210216746,0.5121274427616084,1.3597650907486145,0.4768243999762741,0.7989629703796846,0.23295871445948424,-0.23880560493110126,0.02826992735684619,-0.03911004514660509,1.8735081335636863,-0.5638942876356867,-0.46734630399467275,0.762668016319278,-0.33732182412727213
2,466
Ligase
34
61
3.555597
0.000377
P07814,A0AVT1,P49916,P14868,P50747,P11498,Q7Z6Z7,Q9BW92,Q5JPH6,Q96RQ3,Q9NYK5,O60488,P30520,P49591,P22681,Q9NSD9,P05165,P23381,P11586,Q96J02,P26639,Q15046,Q9HA77,O95573,Q9NP81,P22314,P41252,O43776,Q93034,P48506,Q8N1G4,Q13620,Q9UBE0,O95376
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
126,5,635,389,15,18,155,552,28,34,700,532,679,44,51,459,52,435,185,735,436,347,99,709,618,335,719,91,771,237,769,514,777,244
5,91,532,244,709,52,2267,126,18,185,389,1559,335,51,435,436,679,1268,1270,719,832,237,1354,1058,44,635,15,1155,925,759,1401,1734,514,932,347,28,1242,1163,155,2353,769,1698,771,852,735,34,1540,552,2357,99,1584,810,618,459,1424,700,1854,777,951,2068,1634
4.637142878618707,1.6329179826648552,0.5830937941090167,1.0567387805118416,0.40657274055962805,2.1205507147690597,-1.1877628050053848,1.4758764855204225,2.9517648784557937,1.2070828107445577,0.762668016319278,-0.2717409991326573,0.8353876893846488,2.162387986697736,0.690462087882705,0.690462087882705,0.44163988227236045,-0.03911004514660509,-0.03911004514660509,0.40657274055962805,0.30206435300525497,1.09411123321543,-0.106077830470184,0.13012911860860088,2.2044216937819225,0.4768243999762741,3.231128956611099,0.06211680648946061,0.23295871445948424,0.3716218440786248,-0.1394094247514785,-0.4025214696779287,0.6187594963253328,0.23295871445948424,0.8353876893846488,2.592032399318675,-0.005472043382106115,0.06211680648946061,1.3213694940336442,-1.517439986141119,0.3716218440786248,-0.36996889215618123,0.3716218440786248,0.30206435300525497,0.40657274055962805,2.4609050013050613,-0.23880560493110126,0.5830937941090167,-1.517439986141119,1.6329179826648552,-0.2717409991326573,0.33678607999499527,0.5121274427616084,0.690462087882705,-0.1394094247514785,0.44163988227236045,-0.49962010917283683,0.3716218440786248,0.23295871445948424,-0.7545819832932289,-0.3045794640677411
2,466
Trna metabolic process
27
64
3.430064
0.000603
P26640,P07814,Q9BTE6,P14868,Q9Y3I0,Q9BQ52,Q9BW92,Q5JPH6,Q99575,P49591,Q7L0Y3,Q9NSD9,Q9P2J5,Q92499,Q9Y5Q9,Q08J23,P23381,Q9UPY3,Q9NQT5,P05455,P26639,Q15046,Q9Y224,Q12789,Q9HA77,P78346,O43776
Processes and pathways
GO Biological process
msigdb_gobp
127,126,9,389,555,551,552,28,172,44,181,459,462,58,465,447,435,66,329,432,436,347,355,344,99,220,91
1042,91,432,126,389,435,436,127,1270,719,832,538,1058,44,599,1018,835,1566,220,725,447,344,1689,1067,1405,932,347,28,1616,2131,1533,1075,1242,181,1660,769,940,58,172,2028,551,9,552,945,2313,99,1420,618,329,459,1424,1585,462,2181,1632,816,1214,66,355,702,2068,1955,555,465
0.13012911860860088,1.6329179826648552,0.690462087882705,1.4758764855204225,0.762668016319278,0.690462087882705,0.690462087882705,1.4758764855204225,-0.03911004514660509,0.40657274055962805,0.30206435300525497,0.5830937941090167,0.13012911860860088,2.2044216937819225,0.5121274427616084,0.16429650233449708,0.30206435300525497,-0.2717409991326573,1.1316250081230708,0.40657274055962805,0.690462087882705,0.8353876893846488,-0.36996889215618123,0.13012911860860088,-0.1394094247514785,0.23295871445948424,0.8353876893846488,2.592032399318675,-0.3045794640677411,-0.8799840708301513,-0.23880560493110126,0.13012911860860088,-0.005472043382106115,1.2450300545136346,-0.33732182412727213,0.3716218440786248,0.23295871445948424,1.9961913574668617,1.2831250541224368,-0.691369514566026,0.5830937941090167,3.8135589893360913,0.5830937941090167,0.23295871445948424,-1.3387274219224072,1.6329179826648552,-0.1394094247514785,0.5121274427616084,0.8719435308811879,0.690462087882705,-0.1394094247514785,-0.2717409991326573,0.690462087882705,-0.9731613542657431,-0.3045794640677411,0.33678607999499527,0.02826992735684619,1.8735081335636863,0.8353876893846488,0.44163988227236045,-0.7545819832932289,-0.5958961470236193,0.5830937941090167,0.690462087882705
2,466
Catalytic activity acting on dna
38
68
3.325511
0.000883
Q07864,P54132,O14981,O60832,P19447,P49916,P39748,Q9HCK8,Q92900,P26358,Q02880,P49736,Q12830,P12004,P33993,P33991,Q14839,P11387,Q92499,P51532,Q14527,Q9UPY3,Q9H2U1,P25205,P13010,P29372,P28340,P35251,O14646,Q8IYB8,Q15554,Q13283,P46063,P33992,P52701,P18074,Q9Y2S7,Q9UQE7
Functions
GO Molecular function
msigdb_gomf
130,400,7,626,256,635,396,152,690,149,683,282,543,535,176,175,312,673,58,308,194,66,328,186,433,322,566,567,71,610,209,345,339,338,101,594,382,529
1216,71,7,821,626,964,673,1093,535,1445,433,873,594,256,1051,186,149,914,566,1227,322,175,338,176,1904,1561,567,396,1393,718,1148,339,282,635,919,308,101,400,683,130,1065,1020,543,345,194,882,312,1106,209,849,1695,730,2080,610,799,58,893,690,2277,328,152,2405,66,2169,529,1927,1820,382
-0.005472043382106115,1.7926187250454313,3.963965887756176,0.30206435300525497,0.4768243999762741,0.19857269655533746,0.44163988227236045,0.09606954757438466,0.5830937941090167,-0.17264067204748582,0.690462087882705,0.26745558495361116,0.5121274427616084,1.0195061138420503,0.13012911860860088,1.2070828107445577,1.3597650907486145,0.23295871445948424,0.5475501784669402,-0.005472043382106115,0.8719435308811879,1.2450300545136346,0.8353876893846488,1.2450300545136346,-0.5638942876356867,-0.2717409991326573,0.5475501784669402,0.762668016319278,-0.1394094247514785,0.40657274055962805,0.06211680648946061,0.8353876893846488,0.9824117244906789,0.4768243999762741,0.23295871445948424,0.9086318760961686,1.5934133472710452,0.762668016319278,0.44163988227236045,1.4758764855204225,0.13012911860860088,0.16429650233449708,0.5830937941090167,0.8353876893846488,1.2070828107445577,0.26745558495361116,0.9086318760961686,0.09606954757438466,1.1692816695624557,0.30206435300525497,-0.36996889215618123,0.40657274055962805,-0.786059355940462,0.5121274427616084,0.33678607999499527,1.9961913574668617,0.26745558495361116,0.44163988227236045,-1.218107502027458,0.8719435308811879,1.3597650907486145,-1.924649980401603,1.8735081335636863,-0.9421842433017042,0.6187594963253328,-0.5638942876356867,-0.46734630399467275,0.7989629703796846
2,466
Abnormal soft palate morphology
21
59
3.202727
0.001361
Q9NXE4,P21333,P61313,Q86W42,Q93008,Q13618,P08708,Q9NVI1,P62266,Q13428,Q15436,P18077,P60866,Q69YQ0,Q6PGP7,Q9Y617,Q15392,Q07020,Q14683,A6NHR9,P62899
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
271,257,19,289,150,285,281,158,31,421,43,160,310,196,325,217,88,343,239,229,109
229,1216,955,1386,2316,1006,281,2161,964,160,595,785,257,1487,1350,2125,1606,419,754,1231,1017,310,923,19,1397,1525,1452,1061,756,31,837,2146,109,1873,1398,880,343,421,285,239,1202,88,1279,43,1500,196,766,325,289,1244,150,522,1669,2391,1922,158,271,217,2244
1.09411123321543,-0.005472043382106115,0.19857269655533746,-0.1394094247514785,-1.3686954198284471,0.16429650233449708,0.9824117244906789,-0.9421842433017042,0.19857269655533746,1.2831250541224368,0.5121274427616084,0.33678607999499527,1.0195061138420503,-0.20577244529591113,-0.106077830470184,-0.8799840708301513,-0.3045794640677411,0.7265014927733182,0.3716218440786248,-0.005472043382106115,0.16429650233449708,0.9086318760961686,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.23880560493110126,-0.17264067204748582,0.13012911860860088,0.3716218440786248,2.5043931129264574,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,-0.1394094247514785,0.26745558495361116,0.8353876893846488,0.7265014927733182,0.9824117244906789,1.09411123321543,0.02826992735684619,1.672588769694534,-0.03911004514660509,2.246654540588567,-0.20577244529591113,1.2070828107445577,0.3716218440786248,0.8719435308811879,0.9824117244906789,-0.005472043382106115,1.3597650907486145,0.6187594963253328,-0.33732182412727213,-1.7517557163157798,-0.5638942876356867,1.3213694940336442,1.0195061138420503,1.1692816695624557,-1.0962643994696941
2,466
Helicase activity
38
83
3.137485
0.001704
Q15477,P54132,Q9Y2R4,O14981,P19447,Q9HCK8,Q92900,Q8IY37,Q14562,Q7Z7L1,P49736,Q8TDD1,Q9GZR7,P33993,P33991,Q14839,Q7L014,Q92499,P51532,Q14527,Q9UPY3,Q9H2U1,P25205,P13010,P26196,O14646,Q8IYB8,Q92620,Q13283,Q9HCE1,P46063,P33992,P18074,Q9NRZ9,O60231,Q13206,Q96GQ7,Q9NR30
Functions
GO Molecular function
msigdb_gomf
642,400,412,7,256,152,690,23,287,156,282,299,455,176,175,312,57,58,308,194,66,328,186,433,565,71,610,485,345,617,339,338,594,379,230,512,523,655
703,1216,71,7,1433,230,821,1258,867,1445,433,1263,594,256,186,565,1227,175,338,176,1904,1561,2125,1393,718,1193,339,282,919,308,400,1730,1065,512,345,1570,1022,194,287,882,312,642,1695,1076,57,686,1317,156,988,798,23,610,799,2081,1320,299,58,485,1246,893,690,523,895,1031,1081,455,1707,328,2029,1888,617,152,655,379,948,1543,1212,1291,66,1927,1820,412,1674
0.40657274055962805,-0.005472043382106115,1.7926187250454313,3.963965887756176,-0.17264067204748582,1.09411123321543,0.30206435300525497,-0.03911004514660509,0.26745558495361116,-0.17264067204748582,0.690462087882705,-0.03911004514660509,0.5121274427616084,1.0195061138420503,1.2070828107445577,0.5475501784669402,-0.005472043382106115,1.2450300545136346,0.8353876893846488,1.2450300545136346,-0.5638942876356867,-0.2717409991326573,-0.8799840708301513,-0.1394094247514785,0.40657274055962805,0.02826992735684619,0.8353876893846488,0.9824117244906789,0.23295871445948424,0.9086318760961686,0.762668016319278,-0.4025214696779287,0.13012911860860088,0.6187594963253328,0.8353876893846488,-0.2717409991326573,0.16429650233449708,1.2070828107445577,0.9824117244906789,0.26745558495361116,0.9086318760961686,0.4768243999762741,-0.36996889215618123,0.13012911860860088,2.037454957685927,0.44163988227236045,-0.0726450035074068,1.3213694940336442,0.19857269655533746,0.33678607999499527,2.8151353625654076,0.5121274427616084,0.33678607999499527,-0.786059355940462,-0.0726450035074068,0.9454541305169961,1.9961913574668617,0.6545485118299024,-0.005472043382106115,0.26745558495361116,0.44163988227236045,0.6187594963253328,0.26745558495361116,0.16429650233449708,0.13012911860860088,0.690462087882705,-0.36996889215618123,0.8719435308811879,-0.691369514566026,-0.5318025210216746,0.5121274427616084,1.3597650907486145,0.4768243999762741,0.7989629703796846,0.23295871445948424,-0.23880560493110126,0.02826992735684619,-0.03911004514660509,1.8735081335636863,-0.5638942876356867,-0.46734630399467275,0.762668016319278,-0.33732182412727213
2,466
Ligase activity
44
81
3.13736
0.001705
P26640,P07814,A0AVT1,Q9BTE6,P27708,P50747,P49916,Q13085,P14868,P11498,Q9Y3I0,Q9BW92,Q5JPH6,P38606,Q9Y285,Q96RQ3,O60488,P49588,P30520,P08243,P49591,P05165,Q9NSD9,P17812,Q9P2J5,P23381,P49915,P11586,P22102,Q96J02,P26639,Q15046,P53597,Q9HA77,O95573,Q9NP81,P22314,O43776,P41252,P48506,P54136,Q8N1G4,O00763,Q9UBE0
Functions
GO Molecular function
msigdb_gomf
127,126,5,9,501,15,635,17,389,18,555,552,28,395,702,34,532,538,679,294,44,52,459,675,462,435,189,185,564,735,436,347,443,99,709,618,335,91,719,237,599,769,116,777
5,116,1005,91,532,2266,2053,709,52,2267,1640,126,294,18,185,389,675,564,1559,335,435,1141,1602,436,127,501,679,1268,1146,395,1270,719,832,2091,237,1354,538,1058,44,189,635,15,443,599,1018,835,1966,1064,17,759,2040,795,932,347,28,1616,1533,1408,1242,1163,769,1810,1698,852,735,34,9,552,99,810,618,459,1424,462,1854,777,951,1632,702,2068,555
4.637142878618707,1.5148945458722094,0.16429650233449708,1.6329179826648552,0.5830937941090167,-1.1877628050053848,-0.7545819832932289,0.40657274055962805,2.1205507147690597,-1.1877628050053848,-0.33732182412727213,1.4758764855204225,0.9454541305169961,2.9517648784557937,1.2070828107445577,0.762668016319278,0.44163988227236045,0.5475501784669402,-0.2717409991326573,0.8353876893846488,0.690462087882705,0.06211680648946061,-0.3045794640677411,0.690462087882705,1.4758764855204225,0.6187594963253328,0.44163988227236045,-0.03911004514660509,0.06211680648946061,0.762668016319278,-0.03911004514660509,0.40657274055962805,0.30206435300525497,-0.8174517203305781,1.09411123321543,-0.106077830470184,0.5830937941090167,0.13012911860860088,2.2044216937819225,1.2070828107445577,0.4768243999762741,3.231128956611099,0.690462087882705,0.5121274427616084,0.16429650233449708,0.30206435300525497,-0.6278088272972961,0.13012911860860088,3.090438391144676,0.3716218440786248,-0.7230189299371137,0.33678607999499527,0.23295871445948424,0.8353876893846488,2.592032399318675,-0.3045794640677411,-0.23880560493110126,-0.1394094247514785,-0.005472043382106115,0.06211680648946061,0.3716218440786248,-0.46734630399467275,-0.36996889215618123,0.30206435300525497,0.40657274055962805,2.4609050013050613,3.8135589893360913,0.5830937941090167,1.6329179826648552,0.33678607999499527,0.5121274427616084,0.690462087882705,-0.1394094247514785,0.690462087882705,-0.49962010917283683,0.3716218440786248,0.23295871445948424,-0.3045794640677411,0.44163988227236045,-0.7545819832932289,0.5830937941090167
2,466
Multifunctional enzyme
9
21
3.133127
0.00173
P07814,P54886,P50747,Q13085,P11498,P35573,O00763,Q8N6R0,Q14527
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
126,161,15,17,18,107,116,89,194
116,126,1138,18,1445,564,1559,501,1864,717,107,1837,633,245,15,161,17,194,89,376,813
1.5148945458722094,1.4758764855204225,0.06211680648946061,2.9517648784557937,-0.17264067204748582,0.5475501784669402,-0.2717409991326573,0.6187594963253328,-0.5318025210216746,0.40657274055962805,1.554072857182752,-0.49962010917283683,0.4768243999762741,1.0567387805118416,3.231128956611099,1.2831250541224368,3.090438391144676,1.2070828107445577,1.672588769694534,0.7989629703796846,0.33678607999499527
2,466
Polymicrogyria
23
63
3.13225
0.001735
Q5T440,Q05639,P51659,Q8IY37,P38606,P49591,Q9UN37,Q08J23,Q14204,Q96C86,Q9Y617,Q00610,Q15392,Q9BVA1,Q96F86,Q6ZXV5,Q9NZ01,Q9Y4A5,Q15042,P46821,Q01105,P55011,Q96N66
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
265,261,398,23,395,44,61,447,193,67,217,84,88,489,226,98,240,115,516,108,372,247,406
955,1386,2316,1482,1135,1009,1790,750,595,714,785,751,1487,1145,916,1837,395,2199,597,108,1563,44,1490,398,247,1650,84,372,261,447,1732,571,1199,514,193,763,516,88,1279,728,265,1205,98,23,579,67,1535,226,1666,406,489,856,1710,1983,240,1211,61,1953,1892,1715,115,2121,217
0.19857269655533746,-0.1394094247514785,-1.3686954198284471,-0.20577244529591113,0.06211680648946061,0.16429650233449708,-0.46734630399467275,0.3716218440786248,0.5121274427616084,0.40657274055962805,0.33678607999499527,0.3716218440786248,-0.20577244529591113,0.06211680648946061,0.23295871445948424,-0.49962010917283683,0.762668016319278,-1.034872738573468,0.5121274427616084,1.554072857182752,-0.2717409991326573,2.2044216937819225,-0.20577244529591113,0.762668016319278,1.0567387805118416,-0.33732182412727213,1.7124277556268248,0.7989629703796846,1.0195061138420503,0.690462087882705,-0.4025214696779287,0.5475501784669402,0.02826992735684619,0.6187594963253328,1.2070828107445577,0.3716218440786248,0.6187594963253328,1.672588769694534,-0.03911004514660509,0.40657274055962805,1.0195061138420503,0.02826992735684619,1.6329179826648552,2.8151353625654076,0.5475501784669402,1.8329750185480524,-0.23880560493110126,1.1316250081230708,-0.33732182412727213,0.762668016319278,0.6545485118299024,0.30206435300525497,-0.36996889215618123,-0.6278088272972961,1.09411123321543,0.02826992735684619,1.955113958770151,-0.5958961470236193,-0.5318025210216746,-0.36996889215618123,1.554072857182752,-0.8487597402208368,1.1692816695624557
2,466
Nucleic acid-binding, OB-fold [IPR012340]
15
35
3.012965
0.002587
Q9NQT5,O43776,P33992,P25205,Q15046,Q9Y2L1,P62917,Q9NP64,P33991,Q7KZ85,Q14562,P33993,P63241,P49736,P62266
Sequence
InterPro Superfamily
interpro_homologous_superfamily
329,91,338,186,347,114,207,21,175,288,287,176,27,282,31
91,561,1556,389,186,1053,175,338,176,282,635,1018,31,1312,1453,2146,207,27,1802,1761,1199,1067,287,882,515,347,1241,1242,288,937,1739,21,329,114,1480
1.6329179826648552,0.5475501784669402,-0.2717409991326573,0.762668016319278,1.2070828107445577,0.13012911860860088,1.2450300545136346,0.8353876893846488,1.2450300545136346,0.9824117244906789,0.4768243999762741,0.16429650233449708,2.5043931129264574,-0.0726450035074068,-0.17264067204748582,-0.9111253589916372,1.1692816695624557,2.592032399318675,-0.46734630399467275,-0.4349803471134479,0.02826992735684619,0.13012911860860088,0.9824117244906789,0.26745558495361116,0.6187594963253328,0.8353876893846488,-0.005472043382106115,-0.005472043382106115,0.9824117244906789,0.23295871445948424,-0.4025214696779287,2.905993232831171,0.8719435308811879,1.554072857182752,-0.17264067204748582
2,466
Retinoblastoma gene in cancer
18
39
3.003572
0.002668
Q07864,P16949,P25205,P52701,P09429,Q14683,Q13547,Q96ST3,P78527,P26583,P33993,Q9UNN5,P26358,P24941,P33991,O95239,Q14527,P11802
Processes and pathways
WikiPathways
msigdb_wp
130,218,186,101,39,239,164,375,135,119,176,153,149,390,175,243,194,305
243,415,962,1639,1223,39,964,1093,305,535,1261,218,1052,390,186,149,119,1053,828,175,176,1904,1393,718,101,135,1313,130,1020,164,194,882,239,1530,375,2031,153,529,2244
1.0567387805118416,0.7265014927733182,0.19857269655533746,-0.33732182412727213,-0.005472043382106115,2.289089293908105,0.19857269655533746,0.09606954757438466,0.9086318760961686,0.5830937941090167,-0.03911004514660509,1.1316250081230708,0.13012911860860088,0.762668016319278,1.2070828107445577,1.3597650907486145,1.5148945458722094,0.13012911860860088,0.30206435300525497,1.2450300545136346,1.2450300545136346,-0.5638942876356867,-0.1394094247514785,0.40657274055962805,1.5934133472710452,1.4370167859616607,-0.0726450035074068,1.4758764855204225,0.16429650233449708,1.2831250541224368,1.2070828107445577,0.26745558495361116,1.09411123321543,-0.23880560493110126,0.7989629703796846,-0.691369514566026,1.3597650907486145,0.6187594963253328,-1.0962643994696941
2,466
Damaged dna binding
15
24
2.991879
0.002773
P54132,P20585,O60934,P12004,P52701,P09429,P13010,P19447,P29372,P28340,Q96T60,P39748,P54727,Q13620,P26583
Functions
GO Molecular function
msigdb_gomf
400,500,278,535,101,39,433,256,322,566,376,396,369,514,119
278,39,535,1445,433,594,256,500,1051,119,1053,914,566,322,396,1148,101,400,369,1612,514,1364,1415,376
0.9824117244906789,2.289089293908105,0.5830937941090167,-0.17264067204748582,0.690462087882705,0.5121274427616084,1.0195061138420503,0.6187594963253328,0.13012911860860088,1.5148945458722094,0.13012911860860088,0.23295871445948424,0.5475501784669402,0.8719435308811879,0.762668016319278,0.06211680648946061,1.5934133472710452,0.762668016319278,0.7989629703796846,-0.3045794640677411,0.6187594963253328,-0.106077830470184,-0.1394094247514785,0.7989629703796846
2,466
Abnormal large intestine morphology
21
63
2.935191
0.003333
Q07864,P54132,O15143,P53701,P61313,P08708,P78347,Q13428,P42766,P18077,P50851,P60866,Q9UPY3,Q9Y4P3,Q6PGP7,P10644,Q07020,Q15437,P52701,P62899,P49327
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
130,400,6,146,19,281,420,421,419,160,56,310,66,70,325,320,343,96,101,109,245
6,1130,1132,1434,534,2245,1830,1639,2344,281,964,320,160,500,2014,566,680,1796,1561,916,1606,1055,419,1148,754,1231,245,1934,56,2431,101,146,400,310,923,19,1397,1452,756,837,2146,109,1873,1492,420,343,130,447,421,2059,96,642,1362,1364,849,646,325,1321,1949,1003,1125,66,70
4.116248463498304,0.06211680648946061,0.06211680648946061,-0.17264067204748582,0.5830937941090167,-1.1268418278904393,-0.49962010917283683,-0.33732182412727213,-1.4878354111586123,0.9824117244906789,0.19857269655533746,0.8719435308811879,1.2831250541224368,0.6187594963253328,-0.691369514566026,0.5475501784669402,0.44163988227236045,-0.46734630399467275,-0.2717409991326573,0.23295871445948424,-0.3045794640677411,0.13012911860860088,0.7265014927733182,0.06211680648946061,0.3716218440786248,-0.005472043382106115,1.0567387805118416,-0.5958961470236193,2.0789072337159866,-2.346883769749101,1.5934133472710452,1.3983135936646063,0.762668016319278,0.9086318760961686,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.17264067204748582,0.3716218440786248,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,-0.20577244529591113,0.7265014927733182,0.8353876893846488,1.4758764855204225,0.690462087882705,0.7265014927733182,-0.7545819832932289,1.6329179826648552,0.4768243999762741,-0.106077830470184,-0.106077830470184,0.30206435300525497,0.4768243999762741,0.8719435308811879,-0.0726450035074068,-0.5958961470236193,0.19857269655533746,0.09606954757438466,1.8735081335636863,1.8329750185480524
2,466
Response of eif2ak4 gcn2 to amino acid deficiency
21
73
2.904509
0.003678
P83881,P27635,P61313,P18621,P08708,P62910,P62266,P42766,P40429,P08243,P18077,Q02878,P60866,Q9Y3U8,P39023,Q92616,P62917,Q07020,Q02543,P36578,P62899
Processes and pathways
Reactome Pathways
msigdb_reactome
402,3,19,154,281,30,31,419,418,294,160,296,310,65,440,213,207,343,222,236,109
1556,1187,1557,670,294,281,1440,1049,160,1347,154,596,1051,678,715,3,1603,971,2054,236,1606,440,418,419,1194,754,789,790,1230,1056,1231,1149,833,539,310,600,923,19,1397,2128,1452,541,756,1870,1102,31,1103,836,1312,1234,473,879,1154,1196,837,1731,2146,2077,1197,109,1454,30,1873,207,2273,1062,402,981,222,296,343,213,65
-0.2717409991326573,0.02826992735684619,-0.2717409991326573,0.44163988227236045,0.9454541305169961,0.9824117244906789,-0.17264067204748582,0.13012911860860088,1.2831250541224368,-0.106077830470184,1.3213694940336442,0.5121274427616084,0.13012911860860088,0.44163988227236045,0.40657274055962805,5.122983459255199,-0.3045794640677411,0.19857269655533746,-0.7545819832932289,1.09411123321543,-0.3045794640677411,0.690462087882705,0.7265014927733182,0.7265014927733182,0.02826992735684619,0.3716218440786248,0.33678607999499527,0.33678607999499527,-0.005472043382106115,0.13012911860860088,-0.005472043382106115,0.06211680648946061,0.30206435300525497,0.5830937941090167,0.9086318760961686,0.5121274427616084,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.8799840708301513,-0.17264067204748582,0.5830937941090167,0.3716218440786248,-0.5318025210216746,0.09606954757438466,2.5043931129264574,0.09606954757438466,0.30206435300525497,-0.0726450035074068,-0.005472043382106115,0.6545485118299024,0.26745558495361116,0.06211680648946061,0.02826992735684619,0.30206435300525497,-0.4025214696779287,-0.9111253589916372,-0.786059355940462,0.02826992735684619,1.554072857182752,-0.17264067204748582,2.548101157631834,-0.5318025210216746,1.1692816695624557,-1.218107502027458,0.13012911860860088,0.762668016319278,0.19857269655533746,1.1316250081230708,0.9454541305169961,0.8353876893846488,1.1692816695624557,1.9142203405795986
2,466
Ribosome
19
69
2.869113
0.004116
P83881,P27635,P61313,P18621,P08708,P62910,P62266,P42766,P40429,P18077,Q02878,P60866,Q9Y3U8,P39023,P62917,Q07020,Q02543,P36578,P62899
Processes and pathways
KEGG Pathways
msigdb_kegg
402,3,19,154,281,30,31,419,418,160,296,310,65,440,207,343,222,236,109
1187,1557,670,281,1440,1049,160,1347,154,1051,678,715,3,1603,971,2054,236,1606,440,418,419,1194,754,789,790,1230,1056,1231,1149,833,539,310,600,923,19,1397,2128,1452,541,756,1870,31,1103,836,1312,1234,473,879,1154,1196,837,1731,2146,2077,1197,109,1454,30,1873,207,2273,1062,402,981,222,296,343,1891,65
0.02826992735684619,-0.2717409991326573,0.44163988227236045,0.9824117244906789,-0.17264067204748582,0.13012911860860088,1.2831250541224368,-0.106077830470184,1.3213694940336442,0.13012911860860088,0.44163988227236045,0.40657274055962805,5.122983459255199,-0.3045794640677411,0.19857269655533746,-0.7545819832932289,1.09411123321543,-0.3045794640677411,0.690462087882705,0.7265014927733182,0.7265014927733182,0.02826992735684619,0.3716218440786248,0.33678607999499527,0.33678607999499527,-0.005472043382106115,0.13012911860860088,-0.005472043382106115,0.06211680648946061,0.30206435300525497,0.5830937941090167,0.9086318760961686,0.5121274427616084,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.8799840708301513,-0.17264067204748582,0.5830937941090167,0.3716218440786248,-0.5318025210216746,2.5043931129264574,0.09606954757438466,0.30206435300525497,-0.0726450035074068,-0.005472043382106115,0.6545485118299024,0.26745558495361116,0.06211680648946061,0.02826992735684619,0.30206435300525497,-0.4025214696779287,-0.9111253589916372,-0.786059355940462,0.02826992735684619,1.554072857182752,-0.17264067204748582,2.548101157631834,-0.5318025210216746,1.1692816695624557,-1.218107502027458,0.13012911860860088,0.762668016319278,0.19857269655533746,1.1316250081230708,0.9454541305169961,0.8353876893846488,-0.5318025210216746,1.9142203405795986
2,466
Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]
11
15
2.840994
0.004497
O43776,P07814,P49588,P26639,Q15046,P49591,P14868,P50747,Q9NSD9,Q9BW92,Q9NP81
Sequence
InterPro Superfamily
interpro_homologous_superfamily
91,126,538,436,347,44,389,15,459,552,618
91,126,389,436,1270,538,44,15,347,1616,1242,552,618,459,702
1.6329179826648552,1.4758764855204225,0.762668016319278,0.690462087882705,-0.03911004514660509,0.5830937941090167,2.2044216937819225,3.231128956611099,0.8353876893846488,-0.3045794640677411,-0.005472043382106115,0.5830937941090167,0.5121274427616084,0.690462087882705,0.44163988227236045
2,466
Eukaryotic translation elongation
21
74
2.818935
0.004818
P83881,P27635,Q05639,P61313,P13639,P18621,P08708,P62910,P62266,P42766,P40429,P18077,Q02878,P60866,Q9Y3U8,P39023,P62917,Q07020,Q02543,P36578,P62899
Processes and pathways
Reactome Pathways
msigdb_reactome
402,3,261,19,388,154,281,30,31,419,418,160,296,310,65,440,207,343,222,236,109
1187,1557,670,281,1440,388,1049,160,1347,154,1051,875,678,715,753,3,1680,1603,971,2054,236,1606,440,418,419,1194,754,789,790,1230,1056,1231,1149,833,539,310,600,923,19,1397,2128,1452,541,756,1870,1102,31,1103,836,1312,1234,473,879,1154,1196,837,1731,2146,2077,1197,109,1454,30,1873,207,2273,1062,402,981,222,296,261,343,65
0.02826992735684619,-0.2717409991326573,0.44163988227236045,0.9824117244906789,-0.17264067204748582,0.762668016319278,0.13012911860860088,1.2831250541224368,-0.106077830470184,1.3213694940336442,0.13012911860860088,0.26745558495361116,0.44163988227236045,0.40657274055962805,0.3716218440786248,5.122983459255199,-0.36996889215618123,-0.3045794640677411,0.19857269655533746,-0.7545819832932289,1.09411123321543,-0.3045794640677411,0.690462087882705,0.7265014927733182,0.7265014927733182,0.02826992735684619,0.3716218440786248,0.33678607999499527,0.33678607999499527,-0.005472043382106115,0.13012911860860088,-0.005472043382106115,0.06211680648946061,0.30206435300525497,0.5830937941090167,0.9086318760961686,0.5121274427616084,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.8799840708301513,-0.17264067204748582,0.5830937941090167,0.3716218440786248,-0.5318025210216746,0.09606954757438466,2.5043931129264574,0.09606954757438466,0.30206435300525497,-0.0726450035074068,-0.005472043382106115,0.6545485118299024,0.26745558495361116,0.06211680648946061,0.02826992735684619,0.30206435300525497,-0.4025214696779287,-0.9111253589916372,-0.786059355940462,0.02826992735684619,1.554072857182752,-0.17264067204748582,2.548101157631834,-0.5318025210216746,1.1692816695624557,-1.218107502027458,0.13012911860860088,0.762668016319278,0.19857269655533746,1.1316250081230708,0.9454541305169961,1.0195061138420503,0.8353876893846488,1.9142203405795986
2,466
Helicase
8
19
2.817469
0.00484
P46063,P25205,P13010,P33993,P33991,Q8IY37,Q14562,P49736
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
339,186,433,176,175,23,287,282
1128,1433,821,1445,433,186,1227,175,176,339,282,1065,287,882,1317,798,23,485,690
0.06211680648946061,-0.17264067204748582,0.30206435300525497,-0.17264067204748582,0.690462087882705,1.2070828107445577,-0.005472043382106115,1.2450300545136346,1.2450300545136346,0.8353876893846488,0.9824117244906789,0.13012911860860088,0.9824117244906789,0.26745558495361116,-0.0726450035074068,0.33678607999499527,2.8151353625654076,0.6545485118299024,0.44163988227236045
2,466