term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenocarcinoma of the intestines
| 7
| 20
| 2.194678
| 0.028187
|
Q07864,Q07020,P18077,P62899,P61313,P60866,P08708
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,343,160,109,19,310,281
|
281,160,566,1606,419,1148,754,1231,310,923,19,1397,1452,756,837,2146,109,1873,343,130
|
0.9824117244906789,1.2831250541224368,0.5475501784669402,-0.3045794640677411,0.7265014927733182,0.06211680648946061,0.3716218440786248,-0.005472043382106115,0.9086318760961686,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.17264067204748582,0.3716218440786248,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,0.8353876893846488,1.4758764855204225
| 2,466
|
Histone binding
| 29
| 72
| 2.185382
| 0.028861
|
Q15291,O75151,P25440,Q9HCK8,Q7KZ85,P49736,Q03164,Q12830,Q92688,Q9ULM3,Q8IWS0,Q08945,P33993,Q9BZK7,P42695,P51532,Q13112,Q92785,P39687,O14646,Q15021,P35659,P29375,Q15020,P52701,Q01105,Q5VTR2,Q92922,Q99549
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
404,12,133,152,288,282,542,543,424,47,578,178,176,586,54,308,572,64,568,71,208,204,202,478,101,372,110,649,652
|
1128,71,660,624,1217,821,12,1828,1046,1599,1264,133,202,176,204,568,1055,54,1961,974,282,308,101,922,1358,2093,372,542,178,1020,543,1612,572,2129,2040,1735,478,208,763,404,2115,1531,110,1076,288,1662,578,2262,1772,1942,2194,1847,424,64,649,1079,1248,941,1538,652,1471,1284,2254,586,2151,152,813,1377,1003,47,2198,1383
|
0.06211680648946061,1.7926187250454313,0.44163988227236045,0.4768243999762741,-0.005472043382106115,0.30206435300525497,3.4218094448205134,-0.49962010917283683,0.13012911860860088,-0.3045794640677411,-0.03911004514660509,1.4370167859616607,1.1692816695624557,1.2450300545136346,1.1692816695624557,0.5475501784669402,0.13012911860860088,2.0789072337159866,-0.6278088272972961,0.19857269655533746,0.9824117244906789,0.9086318760961686,1.5934133472710452,0.23295871445948424,-0.106077830470184,-0.8174517203305781,0.7989629703796846,0.5830937941090167,1.2450300545136346,0.16429650233449708,0.5830937941090167,-0.3045794640677411,0.5475501784669402,-0.8799840708301513,-0.7230189299371137,-0.4025214696779287,0.6545485118299024,1.1692816695624557,0.3716218440786248,0.762668016319278,-0.8487597402208368,-0.23880560493110126,1.554072857182752,0.13012911860860088,0.9824117244906789,-0.33732182412727213,0.5475501784669402,-1.1573411038415724,-0.4349803471134479,-0.5958961470236193,-1.0040573144405394,-0.49962010917283683,0.7265014927733182,1.9142203405795986,0.4768243999762741,0.13012911860860088,-0.005472043382106115,0.23295871445948424,-0.23880560493110126,0.4768243999762741,-0.17264067204748582,-0.03911004514660509,-1.1268418278904393,0.5475501784669402,-0.9111253589916372,1.3597650907486145,0.33678607999499527,-0.106077830470184,0.19857269655533746,2.2044216937819225,-1.0040573144405394,-0.106077830470184
| 2,466
|
Cellular response to starvation
| 22
| 81
| 2.182415
| 0.029079
|
P83881,P27635,P61313,P18621,P08708,P38606,P62910,P62266,P42766,P40429,P08243,P18077,Q02878,P60866,Q9Y3U8,P39023,Q92616,P62917,Q07020,Q02543,P36578,P62899
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
402,3,19,154,281,395,30,31,419,418,294,160,296,310,65,440,213,207,343,222,236,109
|
1556,1187,1557,670,294,281,1440,1049,160,1347,154,596,785,1901,1051,678,715,3,1603,971,2054,236,395,1606,440,418,597,419,1194,754,789,790,1230,1056,1231,1149,833,539,310,600,923,19,1397,2108,2128,1452,541,756,1870,1102,31,1103,836,1312,1234,473,879,1154,1196,837,1731,2146,2077,1197,109,1454,30,1873,207,2273,1062,402,981,222,296,343,2221,213,1776,1589,65
|
-0.2717409991326573,0.02826992735684619,-0.2717409991326573,0.44163988227236045,0.9454541305169961,0.9824117244906789,-0.17264067204748582,0.13012911860860088,1.2831250541224368,-0.106077830470184,1.3213694940336442,0.5121274427616084,0.33678607999499527,-0.5638942876356867,0.13012911860860088,0.44163988227236045,0.40657274055962805,5.122983459255199,-0.3045794640677411,0.19857269655533746,-0.7545819832932289,1.09411123321543,0.762668016319278,-0.3045794640677411,0.690462087882705,0.7265014927733182,0.5121274427616084,0.7265014927733182,0.02826992735684619,0.3716218440786248,0.33678607999499527,0.33678607999499527,-0.005472043382106115,0.13012911860860088,-0.005472043382106115,0.06211680648946061,0.30206435300525497,0.5830937941090167,0.9086318760961686,0.5121274427616084,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.8487597402208368,-0.8799840708301513,-0.17264067204748582,0.5830937941090167,0.3716218440786248,-0.5318025210216746,0.09606954757438466,2.5043931129264574,0.09606954757438466,0.30206435300525497,-0.0726450035074068,-0.005472043382106115,0.6545485118299024,0.26745558495361116,0.06211680648946061,0.02826992735684619,0.30206435300525497,-0.4025214696779287,-0.9111253589916372,-0.786059355940462,0.02826992735684619,1.554072857182752,-0.17264067204748582,2.548101157631834,-0.5318025210216746,1.1692816695624557,-1.218107502027458,0.13012911860860088,0.762668016319278,0.19857269655533746,1.1316250081230708,0.9454541305169961,0.8353876893846488,-1.0656082337385886,1.1692816695624557,-0.4349803471134479,-0.2717409991326573,1.9142203405795986
| 2,466
|
Dioxygenase
| 6
| 12
| 2.182394
| 0.02908
|
O75151,Q12797,Q9H6W3,Q7LBC6,O00469,P29375
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
12,284,24,121,241,202
|
241,357,12,2306,202,1652,284,1768,850,121,24,1336
|
1.0567387805118416,0.7989629703796846,3.4218094448205134,-1.3387274219224072,1.1692816695624557,-0.33732182412727213,0.9824117244906789,-0.4349803471134479,0.30206435300525497,1.5148945458722094,2.8151353625654076,-0.0726450035074068
| 2,466
|
Positive regulation of cell morphogenesis involved in differentiation
| 8
| 21
| 2.182096
| 0.029102
|
Q9H2U1,Q9UL25,Q14185,Q9UQB8,P78527,P21333,P61160,P43034
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
328,76,8,216,135,257,371,145
|
706,963,257,1723,145,441,976,1757,371,1650,135,2260,2039,8,761,1107,1207,328,1123,76,216
|
0.40657274055962805,0.19857269655533746,1.0195061138420503,-0.4025214696779287,1.3983135936646063,0.690462087882705,0.19857269655533746,-0.4349803471134479,0.7989629703796846,-0.33732182412727213,1.4370167859616607,-1.1573411038415724,-0.7230189299371137,3.8135589893360913,0.3716218440786248,0.09606954757438466,0.02826992735684619,0.8719435308811879,0.09606954757438466,1.7926187250454313,1.1692816695624557
| 2,466
|
Abnormality of the zygomatic bone
| 23
| 64
| 2.182059
| 0.029105
|
Q07864,P54132,P21333,A5YKK6,P38606,P78347,O60934,Q13428,O75369,O60488,P53992,Q15436,P36507,Q9BZK7,Q9Y4P3,P10644,P46109,P21359,P28482,Q14807,Q15042,P35573,P42704
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,400,257,383,395,420,278,421,534,532,540,43,177,586,70,320,441,80,437,477,516,107,367
|
383,2281,955,1130,532,1434,278,534,2228,1930,1830,320,1303,1094,1304,257,80,2089,437,1681,1561,107,177,395,367,441,975,1490,540,400,1939,420,1493,130,571,1969,421,848,477,1237,516,2059,1202,1279,43,728,644,851,1244,1026,1077,1625,1323,586,856,2278,1034,1949,1209,1003,1715,70,1293,905
|
0.762668016319278,-1.2483757586357453,0.19857269655533746,0.06211680648946061,0.5830937941090167,-0.17264067204748582,0.9824117244906789,0.5830937941090167,-1.0962643994696941,-0.5958961470236193,-0.49962010917283683,0.8719435308811879,-0.0726450035074068,0.09606954757438466,-0.0726450035074068,1.0195061138420503,1.752437029840453,-0.8174517203305781,0.690462087882705,-0.36996889215618123,-0.2717409991326573,1.554072857182752,1.2450300545136346,0.762668016319278,0.7989629703796846,0.690462087882705,0.19857269655533746,-0.20577244529591113,0.5830937941090167,0.762668016319278,-0.5958961470236193,0.7265014927733182,-0.20577244529591113,1.4758764855204225,0.5475501784669402,-0.6278088272972961,0.7265014927733182,0.30206435300525497,0.6545485118299024,-0.005472043382106115,0.6187594963253328,-0.7545819832932289,0.02826992735684619,-0.03911004514660509,2.246654540588567,0.40657274055962805,0.4768243999762741,0.30206435300525497,-0.005472043382106115,0.16429650233449708,0.13012911860860088,-0.3045794640677411,-0.0726450035074068,0.5475501784669402,0.30206435300525497,-1.218107502027458,0.16429650233449708,-0.5958961470236193,0.02826992735684619,0.19857269655533746,-0.36996889215618123,1.8329750185480524,-0.03911004514660509,0.26745558495361116
| 2,466
|
Response to peptide hormone
| 16
| 70
| 2.180106
| 0.02925
|
Q7L576,O60343,Q9BZF1,P07814,P48506,Q9HCD5,P78527,P49770,P40763,Q9UQB8,P09874,P46821,Q13144,Q92572,P11802,O14654
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
326,125,35,126,237,11,135,134,295,216,16,108,147,53,305,331
|
704,2048,331,819,1515,125,1435,909,1186,2270,1832,126,1678,16,1224,2229,305,674,872,1094,470,1011,1305,914,2090,295,633,2162,1055,597,1097,368,108,237,134,1935,720,1150,835,1756,1687,2143,1526,757,980,135,474,1569,147,1159,1807,641,1529,2117,1767,1408,326,1739,2194,53,649,1170,1079,35,11,811,1085,216,1126,2069
|
0.40657274055962805,-0.7545819832932289,0.8353876893846488,0.30206435300525497,-0.23880560493110126,1.4758764855204225,-0.17264067204748582,0.23295871445948424,0.02826992735684619,-1.218107502027458,-0.49962010917283683,1.4758764855204225,-0.36996889215618123,3.1840096027515767,-0.005472043382106115,-1.0962643994696941,0.9086318760961686,0.44163988227236045,0.26745558495361116,0.09606954757438466,0.6545485118299024,0.16429650233449708,-0.0726450035074068,0.23295871445948424,-0.8174517203305781,0.9454541305169961,0.4768243999762741,-0.9421842433017042,0.13012911860860088,0.5121274427616084,0.09606954757438466,0.7989629703796846,1.554072857182752,1.09411123321543,1.4370167859616607,-0.5958961470236193,0.40657274055962805,0.06211680648946061,0.30206435300525497,-0.4349803471134479,-0.36996889215618123,-0.9111253589916372,-0.23880560493110126,0.3716218440786248,0.19857269655533746,1.4370167859616607,0.6545485118299024,-0.2717409991326573,1.3983135936646063,0.06211680648946061,-0.46734630399467275,0.4768243999762741,-0.23880560493110126,-0.8487597402208368,-0.4349803471134479,-0.1394094247514785,0.8719435308811879,-0.4025214696779287,-1.0040573144405394,2.1205507147690597,0.4768243999762741,0.06211680648946061,0.13012911860860088,2.417633637154997,3.5671075805179417,0.33678607999499527,0.13012911860860088,1.1692816695624557,0.09606954757438466,-0.7545819832932289
| 2,466
|
Axon extension
| 11
| 24
| 2.178385
| 0.029377
|
Q7L576,Q9UL25,Q96ST3,Q9NQC3,P18206,P43034,P46821,P07900,Q93008,Q9UPN3,P78344
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
326,76,375,524,364,145,108,334,150,463,445
|
2173,1959,334,497,1720,364,1267,145,108,720,976,445,982,1161,886,1107,326,150,375,1672,524,1123,76,463
|
-0.9731613542657431,-0.6278088272972961,0.8353876893846488,0.6187594963253328,-0.4025214696779287,0.7989629703796846,-0.03911004514660509,1.3983135936646063,1.554072857182752,0.40657274055962805,0.19857269655533746,0.690462087882705,0.19857269655533746,0.06211680648946061,0.26745558495361116,0.09606954757438466,0.8719435308811879,1.3597650907486145,0.7989629703796846,-0.33732182412727213,0.6187594963253328,0.09606954757438466,1.7926187250454313,0.690462087882705
| 2,466
|
Circadian regulation of gene expression
| 10
| 18
| 2.171941
| 0.02986
|
Q03164,Q00839,Q13547,Q92769,O14744,Q9BQG0,P11387,P29375,Q7Z6Z7,Q13330
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
542,842,164,351,466,584,673,202,155,544
|
466,819,673,202,1097,1491,1061,842,542,1157,544,164,155,351,1079,584,1327,1336
|
0.6545485118299024,0.30206435300525497,0.44163988227236045,1.1692816695624557,0.09606954757438466,-0.20577244529591113,0.13012911860860088,0.30206435300525497,0.5830937941090167,0.06211680648946061,0.5830937941090167,1.2831250541224368,1.3213694940336442,0.8353876893846488,0.13012911860860088,0.5475501784669402,-0.0726450035074068,-0.0726450035074068
| 2,466
|
Macrotia
| 28
| 69
| 2.169809
| 0.030021
|
P27635,O14617,O95602,P21333,P51571,O00170,Q7Z6Z7,P38606,P78347,O60934,Q12830,P08243,P54886,Q8IWS0,P22681,P36507,Q9BZK7,Q92785,Q12756,Q9Y4P3,Q9Y617,O43776,Q14683,Q96ST3,Q15042,Q01105,P55011,Q9UQE7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
3,124,494,257,507,384,155,395,420,278,543,294,161,578,51,177,586,64,571,70,217,91,239,375,516,372,247,529
|
384,1294,2281,124,1386,91,1636,278,494,912,294,2229,2325,785,257,51,565,3,1561,177,1837,2348,395,2416,507,1490,161,247,1608,1061,420,372,1493,571,543,1360,239,763,516,2059,1364,646,1619,155,578,2082,802,1026,1507,1576,2194,64,1323,1535,375,1171,1947,900,586,856,1710,2181,1003,1125,1479,529,1955,70,217
|
0.762668016319278,-0.0726450035074068,-1.2483757586357453,1.4758764855204225,-0.1394094247514785,1.6329179826648552,-0.33732182412727213,0.9824117244906789,0.6187594963253328,0.23295871445948424,0.9454541305169961,-1.0962643994696941,-1.3985896961877513,0.33678607999499527,1.0195061138420503,2.162387986697736,0.5475501784669402,5.122983459255199,-0.2717409991326573,1.2450300545136346,-0.49962010917283683,-1.4878354111586123,0.762668016319278,-2.0386126041119432,0.6187594963253328,-0.20577244529591113,1.2831250541224368,1.0567387805118416,-0.3045794640677411,0.13012911860860088,0.7265014927733182,0.7989629703796846,-0.20577244529591113,0.5475501784669402,0.5830937941090167,-0.106077830470184,1.09411123321543,0.3716218440786248,0.6187594963253328,-0.7545819832932289,-0.106077830470184,0.4768243999762741,-0.3045794640677411,1.3213694940336442,0.5475501784669402,-0.786059355940462,0.33678607999499527,0.16429650233449708,-0.20577244529591113,-0.2717409991326573,-1.0040573144405394,1.9142203405795986,-0.0726450035074068,-0.23880560493110126,0.7989629703796846,0.06211680648946061,-0.5958961470236193,0.26745558495361116,0.5475501784669402,0.30206435300525497,-0.36996889215618123,-0.9731613542657431,0.19857269655533746,0.09606954757438466,-0.17264067204748582,0.6187594963253328,-0.5958961470236193,1.8329750185480524,1.1692816695624557
| 2,466
|
Vesicle transport along microtubule
| 7
| 10
| 2.168977
| 0.030084
|
O14617,P33176,O00203,P43034,Q92572,P62820,Q14204
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
124,438,293,145,53,283,193
|
293,124,914,438,145,283,571,193,53,861
|
0.9454541305169961,1.4758764855204225,0.23295871445948424,0.690462087882705,1.3983135936646063,0.9824117244906789,0.5475501784669402,1.2070828107445577,2.1205507147690597,0.30206435300525497
| 2,466
|
Chromatin regulator
| 25
| 71
| 2.165752
| 0.03033
|
Q15291,O75151,P25440,P51610,Q9HCK8,P26358,Q9H6W3,Q03164,Q12830,Q13547,Q86U86,Q14839,P51532,Q14527,Q92785,Q92769,O14646,P35659,P29375,O14744,Q9Y4A5,A6NHR9,Q5VTR2,Q96GM5,Q7LBC6
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
404,12,133,397,152,149,24,542,543,164,576,312,308,194,64,351,71,204,202,466,115,229,110,522,121
|
229,1676,71,466,819,1217,821,1184,909,12,1786,1828,912,1829,133,149,1227,202,204,1725,308,397,1965,1358,842,542,1020,2428,543,2129,844,164,194,312,1071,763,404,2115,110,1407,1076,121,576,1662,2262,1772,351,64,649,1578,522,2132,895,941,1538,2254,586,24,1034,152,1210,1175,1332,2279,1377,1855,1927,1820,1336,115,1040
|
1.09411123321543,-0.36996889215618123,1.7926187250454313,0.6545485118299024,0.30206435300525497,-0.005472043382106115,0.30206435300525497,0.02826992735684619,0.23295871445948424,3.4218094448205134,-0.46734630399467275,-0.49962010917283683,0.23295871445948424,-0.49962010917283683,1.4370167859616607,1.3597650907486145,-0.005472043382106115,1.1692816695624557,1.1692816695624557,-0.4025214696779287,0.9086318760961686,0.762668016319278,-0.6278088272972961,-0.106077830470184,0.30206435300525497,0.5830937941090167,0.16429650233449708,-2.2635366231677914,0.5830937941090167,-0.8799840708301513,0.30206435300525497,1.2831250541224368,1.2070828107445577,0.9086318760961686,0.13012911860860088,0.3716218440786248,0.762668016319278,-0.8487597402208368,1.554072857182752,-0.1394094247514785,0.13012911860860088,1.5148945458722094,0.5475501784669402,-0.33732182412727213,-1.1573411038415724,-0.4349803471134479,0.8353876893846488,1.9142203405795986,0.4768243999762741,-0.2717409991326573,0.6187594963253328,-0.8799840708301513,0.26745558495361116,0.23295871445948424,-0.23880560493110126,-1.1268418278904393,0.5475501784669402,2.8151353625654076,0.16429650233449708,1.3597650907486145,0.02826992735684619,0.06211680648946061,-0.0726450035074068,-1.218107502027458,-0.106077830470184,-0.49962010917283683,-0.5638942876356867,-0.46734630399467275,-0.0726450035074068,1.554072857182752,0.16429650233449708
| 2,466
|
Lateral plasma membrane
| 6
| 19
| 2.162291
| 0.030596
|
Q7KZI7,P53985,P33527,P46940,P55011,Q9ULV4
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
63,4,439,260,247,528
|
704,1186,1555,1719,1446,1229,439,1796,1014,260,1150,4,247,843,572,762,63,900,528
|
0.40657274055962805,0.02826992735684619,-0.2717409991326573,-0.4025214696779287,-0.17264067204748582,-0.005472043382106115,0.690462087882705,-0.46734630399467275,0.16429650233449708,1.0195061138420503,0.06211680648946061,5.068220122060361,1.0567387805118416,0.30206435300525497,0.5475501784669402,0.3716218440786248,1.9142203405795986,0.26745558495361116,0.6187594963253328
| 2,466
|
Inguinal hernia
| 22
| 61
| 2.161771
| 0.030636
|
P27635,P21333,P24928,P43034,P38606,P78347,O75369,P54886,Q9NSD9,Q69YQ0,Q9Y4P3,Q6PGP7,P46109,P28482,Q8NBU5,P22314,Q96ST3,Q9Y4A5,A6NHR9,Q13620,Q7LBC6,O00469
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
3,257,258,145,395,420,534,161,459,196,70,325,441,437,82,335,375,115,229,514,121,241
|
229,241,2281,1386,1859,534,1342,1009,2325,257,2089,335,258,565,3,437,1229,716,1681,1561,395,145,441,975,2431,540,161,1757,1871,420,1568,1652,1732,514,763,2059,642,1693,1768,196,766,646,325,1076,121,851,82,2082,1077,1414,375,1672,1034,459,2182,1003,1335,1479,1715,115,70
|
1.09411123321543,1.0567387805118416,-1.2483757586357453,-0.1394094247514785,-0.5318025210216746,0.5830937941090167,-0.106077830470184,0.16429650233449708,-1.3985896961877513,1.0195061138420503,-0.8174517203305781,0.8353876893846488,1.0195061138420503,0.5475501784669402,5.122983459255199,0.690462087882705,-0.005472043382106115,0.40657274055962805,-0.36996889215618123,-0.2717409991326573,0.762668016319278,1.3983135936646063,0.690462087882705,0.19857269655533746,-2.346883769749101,0.5830937941090167,1.2831250541224368,-0.4349803471134479,-0.5318025210216746,0.7265014927733182,-0.2717409991326573,-0.33732182412727213,-0.4025214696779287,0.6187594963253328,0.3716218440786248,-0.7545819832932289,0.4768243999762741,-0.36996889215618123,-0.4349803471134479,1.2070828107445577,0.3716218440786248,0.4768243999762741,0.8719435308811879,0.13012911860860088,1.5148945458722094,0.30206435300525497,1.752437029840453,-0.786059355940462,0.13012911860860088,-0.1394094247514785,0.7989629703796846,-0.33732182412727213,0.16429650233449708,0.690462087882705,-0.9731613542657431,0.19857269655533746,-0.0726450035074068,-0.17264067204748582,-0.36996889215618123,1.554072857182752,1.8329750185480524
| 2,466
|
Aminoacyl-tRNA synthetase
| 6
| 16
| 2.161612
| 0.030648
|
O43776,Q15046,P49591,P14868,Q9NSD9,Q9HA77
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
91,347,44,389,459,99
|
91,389,435,1270,719,1058,44,932,347,1242,769,99,618,459,1424,2068
|
1.6329179826648552,0.762668016319278,0.690462087882705,-0.03911004514660509,0.40657274055962805,0.13012911860860088,2.2044216937819225,0.23295871445948424,0.8353876893846488,-0.005472043382106115,0.3716218440786248,1.6329179826648552,0.5121274427616084,0.690462087882705,-0.1394094247514785,-0.7545819832932289
| 2,466
|
Zinc finger, RING/FYVE/PHD-type [IPR013083]
| 19
| 42
| 2.159141
| 0.030839
|
P19474,O75151,Q03164,Q12830,Q7Z6E9,P22681,Q9BTC0,Q14839,Q14527,Q92785,O14964,Q9UPN9,P29375,Q9H270,Q7Z3T8,Q15075,Q5VTR2,Q9NRL2,O95376
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
499,12,542,543,168,51,315,312,194,64,183,86,202,491,111,517,110,525,244
|
183,624,662,909,12,244,1829,499,51,202,1098,542,543,844,1655,795,194,312,517,1239,110,111,168,578,1942,803,64,2355,941,1538,2000,2043,315,491,525,1377,1003,1713,86,1336,2170,1634
|
1.2070828107445577,0.4768243999762741,0.44163988227236045,0.23295871445948424,3.4218094448205134,1.0567387805118416,-0.49962010917283683,0.6187594963253328,2.162387986697736,1.1692816695624557,0.09606954757438466,0.5830937941090167,0.5830937941090167,0.30206435300525497,-0.33732182412727213,0.33678607999499527,1.2070828107445577,0.9086318760961686,0.6187594963253328,-0.005472043382106115,1.554072857182752,1.554072857182752,1.2831250541224368,0.5475501784669402,-0.5958961470236193,0.33678607999499527,1.9142203405795986,-1.517439986141119,0.23295871445948424,-0.23880560493110126,-0.6596330468559235,-0.7230189299371137,0.9086318760961686,0.6545485118299024,0.6187594963253328,-0.106077830470184,0.19857269655533746,-0.36996889215618123,1.7124277556268248,-0.0726450035074068,-0.9421842433017042,-0.3045794640677411
| 2,466
|
Chronic constipation
| 7
| 24
| 2.153229
| 0.031301
|
P55795,O75165,Q9BZI7,P55011,Q93008,P63241,Q04637
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
401,100,327,247,150,27,129
|
100,1598,1259,1601,1490,247,401,1061,27,1398,2019,129,1402,1108,607,1619,851,1576,150,425,1249,900,327,1672
|
1.5934133472710452,-0.3045794640677411,-0.03911004514660509,-0.3045794640677411,-0.20577244529591113,1.0567387805118416,0.762668016319278,0.13012911860860088,2.592032399318675,-0.1394094247514785,-0.691369514566026,1.4758764855204225,-0.1394094247514785,0.09606954757438466,0.5121274427616084,-0.3045794640677411,0.30206435300525497,-0.2717409991326573,1.3597650907486145,0.7265014927733182,-0.005472043382106115,0.26745558495361116,0.8719435308811879,-0.33732182412727213
| 2,466
|
Hepatocyte growth factor receptor signaling
| 6
| 11
| 2.148204
| 0.031698
|
Q14185,P40763,P46109,Q9NWH9,P28482,P36507
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
8,295,441,113,437,177
|
1959,1142,437,177,295,441,757,1493,474,8,113
|
-0.6278088272972961,0.06211680648946061,0.690462087882705,1.2450300545136346,0.9454541305169961,0.690462087882705,0.3716218440786248,-0.20577244529591113,0.6545485118299024,3.8135589893360913,1.554072857182752
| 2,466
|
Anal atresia
| 7
| 19
| 2.148114
| 0.031705
|
O60934,P29372,P53701,Q86W42,Q93008,Q69YQ0,Q9NVI1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
278,322,146,289,150,196,158
|
662,2009,1859,278,2089,322,916,1351,146,540,196,289,1281,1369,1077,150,375,1034,158
|
0.44163988227236045,-0.691369514566026,-0.5318025210216746,0.9824117244906789,-0.8174517203305781,0.8719435308811879,0.23295871445948424,-0.106077830470184,1.3983135936646063,0.5830937941090167,1.2070828107445577,0.9824117244906789,-0.03911004514660509,-0.106077830470184,0.13012911860860088,1.3597650907486145,0.7989629703796846,0.16429650233449708,1.3213694940336442
| 2,466
|
Sloping forehead
| 15
| 35
| 2.148065
| 0.031709
|
Q9NXE4,P26640,O60934,Q9H267,Q96T60,Q9Y617,P08243,P35606,P98175,A5YKK6,Q15021,Q15003,P42695,Q08J23,Q9NVI1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
271,127,278,377,376,217,294,259,446,383,208,546,54,447,158
|
383,1386,1132,1434,278,294,751,127,259,54,832,921,1608,446,1313,447,1201,546,208,1362,1108,1620,1244,2083,580,1323,1535,376,2179,377,1709,1922,158,271,217
|
0.762668016319278,-0.1394094247514785,0.06211680648946061,-0.17264067204748582,0.9824117244906789,0.9454541305169961,0.3716218440786248,1.4758764855204225,1.0195061138420503,2.0789072337159866,0.30206435300525497,0.23295871445948424,-0.3045794640677411,0.690462087882705,-0.0726450035074068,0.690462087882705,0.02826992735684619,0.5830937941090167,1.1692816695624557,-0.106077830470184,0.09606954757438466,-0.3045794640677411,-0.005472043382106115,-0.786059355940462,0.5475501784669402,-0.0726450035074068,-0.23880560493110126,0.7989629703796846,-0.9731613542657431,0.7989629703796846,-0.36996889215618123,-0.5638942876356867,1.3213694940336442,1.0195061138420503,1.1692816695624557
| 2,466
|
Translation factor activity rna binding
| 16
| 51
| 2.147527
| 0.031751
|
Q7Z2Z2,O43432,P15170,Q9Y450,Q05639,Q9ULC4,O75821,O60841,P49770,Q92616,Q8NE71,Q13144,P13639,P63241,Q14152,Q04637
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
268,90,321,272,261,104,414,73,134,213,212,147,388,27,131,129
|
906,744,663,779,90,1993,73,414,1896,1556,388,321,596,874,875,753,1680,2232,1563,134,1729,1019,1756,1395,1451,1730,637,27,445,129,261,147,2078,131,1529,1022,2059,1882,268,1317,212,213,993,1413,809,811,1545,1085,104,860,272
|
0.23295871445948424,0.3716218440786248,0.44163988227236045,0.33678607999499527,1.6329179826648552,-0.6596330468559235,1.7926187250454313,0.7265014927733182,-0.5638942876356867,-0.2717409991326573,0.762668016319278,0.8719435308811879,0.5121274427616084,0.26745558495361116,0.26745558495361116,0.3716218440786248,-0.36996889215618123,-1.0962643994696941,-0.2717409991326573,1.4370167859616607,-0.4025214696779287,0.16429650233449708,-0.4349803471134479,-0.1394094247514785,-0.17264067204748582,-0.4025214696779287,0.4768243999762741,2.592032399318675,0.690462087882705,1.4758764855204225,1.0195061138420503,1.3983135936646063,-0.786059355940462,1.4758764855204225,-0.23880560493110126,0.16429650233449708,-0.7545819832932289,-0.5318025210216746,1.0195061138420503,-0.0726450035074068,1.1692816695624557,1.1692816695624557,0.19857269655533746,-0.1394094247514785,0.33678607999499527,0.33678607999499527,-0.23880560493110126,0.13012911860860088,1.5934133472710452,0.30206435300525497,1.0195061138420503
| 2,466
|
Abnormal aortic morphology
| 31
| 82
| 2.146946
| 0.031798
|
Q8N5F7,P21333,P53701,P61313,Q7Z6Z7,P08708,Q9NVI1,P78347,Q12830,O75369,P42766,P53992,P54886,P18077,Q14839,P60866,Q69YQ0,Q9Y4P3,P26196,P46109,P21359,P53597,P28482,P55263,Q07020,Q6ZXV5,Q06124,Q9Y4A5,P62899,P46821,P55011
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
139,257,146,19,155,281,158,420,543,534,419,540,161,160,312,310,196,70,565,441,80,443,437,206,343,98,474,115,109,108,247
|
1294,1132,1434,534,2245,912,1830,1598,2036,281,160,629,257,80,2089,565,437,1229,716,1561,1015,1606,419,441,754,1231,108,1058,443,146,540,161,247,206,570,310,923,19,1397,1525,1452,1061,756,837,2146,109,1873,420,880,1493,1652,474,343,543,1360,847,312,2059,1362,196,766,2234,1076,98,1619,155,1244,139,2041,1077,651,1947,1034,158,2137,2182,1003,1821,1592,115,70,905
|
-0.0726450035074068,0.06211680648946061,-0.17264067204748582,0.5830937941090167,-1.1268418278904393,0.23295871445948424,-0.49962010917283683,-0.3045794640677411,-0.7230189299371137,0.9824117244906789,1.2831250541224368,0.4768243999762741,1.0195061138420503,1.752437029840453,-0.8174517203305781,0.5475501784669402,0.690462087882705,-0.005472043382106115,0.40657274055962805,-0.2717409991326573,0.16429650233449708,-0.3045794640677411,0.7265014927733182,0.690462087882705,0.3716218440786248,-0.005472043382106115,1.554072857182752,0.13012911860860088,0.690462087882705,1.3983135936646063,0.5830937941090167,1.2831250541224368,1.0567387805118416,1.1692816695624557,0.5475501784669402,0.9086318760961686,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.23880560493110126,-0.17264067204748582,0.13012911860860088,0.3716218440786248,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,0.7265014927733182,0.26745558495361116,-0.20577244529591113,-0.33732182412727213,0.6545485118299024,0.8353876893846488,0.5830937941090167,-0.106077830470184,0.30206435300525497,0.9086318760961686,-0.7545819832932289,-0.106077830470184,1.2070828107445577,0.3716218440786248,-1.0962643994696941,0.13012911860860088,1.6329179826648552,-0.3045794640677411,1.3213694940336442,-0.005472043382106115,1.4370167859616607,-0.7230189299371137,0.13012911860860088,0.4768243999762741,-0.5958961470236193,0.16429650233449708,1.3213694940336442,-0.8799840708301513,-0.9731613542657431,0.19857269655533746,-0.46734630399467275,-0.2717409991326573,1.554072857182752,1.8329750185480524,0.26745558495361116
| 2,466
|
T cell differentiation
| 8
| 24
| 2.142887
| 0.032122
|
O14617,P09429,Q8N5F7,P24390,P78527,P40763,O00203,Q16566
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
124,39,139,234,135,295,293,97
|
293,124,780,1387,1789,333,1598,1186,1639,39,965,234,1836,1796,2054,295,597,1939,1154,135,1313,97,139,1978
|
0.9454541305169961,1.4758764855204225,0.33678607999499527,-0.1394094247514785,-0.46734630399467275,0.8353876893846488,-0.3045794640677411,0.02826992735684619,-0.33732182412727213,2.289089293908105,0.19857269655533746,1.09411123321543,-0.49962010917283683,-0.46734630399467275,-0.7545819832932289,0.9454541305169961,0.5121274427616084,-0.5958961470236193,0.06211680648946061,1.4370167859616607,-0.0726450035074068,1.6329179826648552,1.4370167859616607,-0.6278088272972961
| 2,466
|
Irregular hyperpigmentation
| 24
| 54
| 2.141586
| 0.032227
|
P54132,Q15477,P19447,Q06136,Q7Z6Z7,Q9NVI1,O60934,Q12830,Q15436,P22681,P36507,Q6PGP7,P26196,P10644,P21359,P28482,Q15437,Q06124,P52701,P18074,Q96ST3,P42345,P55011,Q15149
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
400,642,256,20,155,158,278,543,43,51,177,325,565,320,80,437,96,474,101,594,375,597,247,250
|
1294,1132,1434,626,278,2228,2245,1638,912,1830,1599,1009,964,320,1642,594,256,80,2014,51,565,437,680,177,597,1148,101,834,400,247,1061,1493,474,20,543,1360,848,250,43,96,642,1693,1362,325,1619,155,2194,375,1947,2357,158,812,1479,2152
|
-0.0726450035074068,0.06211680648946061,-0.17264067204748582,0.4768243999762741,0.9824117244906789,-1.0962643994696941,-1.1268418278904393,-0.33732182412727213,0.23295871445948424,-0.49962010917283683,-0.3045794640677411,0.16429650233449708,0.19857269655533746,0.8719435308811879,-0.33732182412727213,0.5121274427616084,1.0195061138420503,1.752437029840453,-0.691369514566026,2.162387986697736,0.5475501784669402,0.690462087882705,0.44163988227236045,1.2450300545136346,0.5121274427616084,0.06211680648946061,1.5934133472710452,0.30206435300525497,0.762668016319278,1.0567387805118416,0.13012911860860088,-0.20577244529591113,0.6545485118299024,2.9517648784557937,0.5830937941090167,-0.106077830470184,0.30206435300525497,1.0567387805118416,2.246654540588567,1.6329179826648552,0.4768243999762741,-0.36996889215618123,-0.106077830470184,0.8719435308811879,-0.3045794640677411,1.3213694940336442,-1.0040573144405394,0.7989629703796846,-0.5958961470236193,-1.517439986141119,1.3213694940336442,0.33678607999499527,-0.17264067204748582,-0.9111253589916372
| 2,466
|
Recurrent lower respiratory tract infections
| 7
| 22
| 2.141269
| 0.032252
|
O60934,P11586,P78527,P40763,O00203,P50851,Q93008
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
278,185,135,295,293,56,150
|
293,278,866,1789,333,964,1720,185,1303,1601,1143,295,56,1650,1398,135,1527,1652,150,2150,900,813
|
0.9454541305169961,0.9824117244906789,0.26745558495361116,-0.46734630399467275,0.8353876893846488,0.19857269655533746,-0.4025214696779287,1.2070828107445577,-0.0726450035074068,-0.3045794640677411,0.06211680648946061,0.9454541305169961,2.0789072337159866,-0.33732182412727213,-0.1394094247514785,1.4370167859616607,-0.23880560493110126,-0.33732182412727213,1.3597650907486145,-0.9111253589916372,0.26745558495361116,0.33678607999499527
| 2,466
|
Armadillo-type fold [IPR016024]
| 43
| 124
| 2.138941
| 0.03244
|
Q7Z4Q2,O14617,Q8TCG1,O14981,Q14185,Q13200,P78527,Q13144,Q9HAV4,Q92538,Q93008,Q9UPU5,Q7Z6Z7,Q99570,Q9ULT8,Q8N201,O00629,Q15397,O00203,Q96T76,Q9NTI5,Q9H4A4,P50851,P42695,P78344,O14980,O15397,O75122,Q92616,Q29RF7,P21359,Q86Y56,Q15021,Q00610,Q9H270,O43432,O75165,P55060,Q86VP6,Q9Y4A5,O75691,Q14008,Q04637
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
269,124,405,7,8,262,135,147,148,291,150,25,155,157,32,169,37,297,293,453,317,316,56,54,445,427,428,74,213,348,80,211,208,84,491,90,100,472,374,115,231,249,129
|
293,556,2156,37,1676,124,427,7,428,90,820,2071,668,1134,2009,1435,74,100,469,231,1007,1046,1597,1224,1446,80,1229,2248,1796,597,54,56,2188,1449,834,1729,472,1455,445,135,84,1609,129,2020,1459,147,262,249,8,1360,796,602,1275,1735,208,297,348,934,574,986,1504,935,645,1407,1770,646,1466,1845,1882,269,155,550,374,211,2207,169,1244,405,939,990,991,291,213,1916,894,150,1248,1249,453,1029,157,2240,584,900,2003,2396,1887,944,491,695,316,901,148,1251,317,1037,1542,1475,2045,1211,1545,1589,1818,1213,32,25,1179,953,1383,115,1040,1127,1086,1004
|
0.9454541305169961,0.5475501784669402,-0.9421842433017042,2.331728784771444,-0.36996889215618123,1.4758764855204225,0.690462087882705,3.963965887756176,0.690462087882705,1.6329179826648552,0.30206435300525497,-0.786059355940462,0.44163988227236045,0.06211680648946061,-0.691369514566026,-0.17264067204748582,1.7926187250454313,1.5934133472710452,0.6545485118299024,1.09411123321543,0.16429650233449708,0.13012911860860088,-0.3045794640677411,-0.005472043382106115,-0.17264067204748582,1.752437029840453,-0.005472043382106115,-1.1268418278904393,-0.46734630399467275,0.5121274427616084,2.0789072337159866,2.0789072337159866,-1.0040573144405394,-0.17264067204748582,0.30206435300525497,-0.4025214696779287,0.6545485118299024,-0.17264067204748582,0.690462087882705,1.4370167859616607,1.7124277556268248,-0.3045794640677411,1.4758764855204225,-0.691369514566026,-0.17264067204748582,1.3983135936646063,1.0195061138420503,1.0567387805118416,3.8135589893360913,-0.106077830470184,0.33678607999499527,0.5121274427616084,-0.03911004514660509,-0.4025214696779287,1.1692816695624557,0.9454541305169961,0.8353876893846488,0.23295871445948424,0.5475501784669402,0.19857269655533746,-0.20577244529591113,0.23295871445948424,0.4768243999762741,-0.1394094247514785,-0.4349803471134479,0.4768243999762741,-0.17264067204748582,-0.49962010917283683,-0.5318025210216746,1.0195061138420503,1.3213694940336442,0.5830937941090167,0.7989629703796846,1.1692816695624557,-1.034872738573468,1.2831250541224368,-0.005472043382106115,0.762668016319278,0.23295871445948424,0.19857269655533746,0.19857269655533746,0.9824117244906789,1.1692816695624557,-0.5638942876356867,0.26745558495361116,1.3597650907486145,-0.005472043382106115,-0.005472043382106115,0.690462087882705,0.16429650233449708,1.3213694940336442,-1.0962643994696941,0.5475501784669402,0.26745558495361116,-0.6596330468559235,-1.8096517939961023,-0.5318025210216746,0.23295871445948424,0.6545485118299024,0.44163988227236045,0.9086318760961686,0.26745558495361116,1.3983135936646063,-0.005472043382106115,0.9086318760961686,0.16429650233449708,-0.23880560493110126,-0.17264067204748582,-0.7230189299371137,0.02826992735684619,-0.23880560493110126,-0.2717409991326573,-0.46734630399467275,0.02826992735684619,2.5043931129264574,2.8151353625654076,0.06211680648946061,0.23295871445948424,-0.106077830470184,1.554072857182752,0.16429650233449708,0.09606954757438466,0.13012911860860088,0.19857269655533746
| 2,466
|
Postsynapse organization
| 13
| 26
| 2.138235
| 0.032498
|
Q12756,Q9H2U1,O15020,O60678,P19022,Q9UQB8,P46109,P61160,P43034,O15258,Q15334,Q96HC4,P11142
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
571,328,274,625,629,216,441,371,145,49,179,251,672
|
274,49,625,672,1345,1139,629,1390,145,441,1757,371,982,1063,571,1161,761,179,1501,1107,1978,251,1249,328,1123,216
|
0.9824117244906789,2.162387986697736,0.4768243999762741,0.44163988227236045,-0.106077830470184,0.06211680648946061,0.4768243999762741,-0.1394094247514785,1.3983135936646063,0.690462087882705,-0.4349803471134479,0.7989629703796846,0.19857269655533746,0.13012911860860088,0.5475501784669402,0.06211680648946061,0.3716218440786248,1.2450300545136346,-0.20577244529591113,0.09606954757438466,-0.6278088272972961,1.0567387805118416,-0.005472043382106115,0.8719435308811879,0.09606954757438466,1.1692816695624557
| 2,466
|
Poor speech
| 27
| 68
| 2.136628
| 0.032628
|
Q05639,P27708,P51610,Q93008,Q9Y399,P38606,O60488,P49591,Q08J23,Q14204,Q12756,Q96C86,Q9BZI7,P55263,Q00610,Q9H270,Q96F86,Q9NZ01,Q14683,Q9Y4A5,Q14738,Q01105,P55011,Q7Z392,Q9UQE7,P42704,Q96N66
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
261,501,397,150,554,395,532,44,447,193,571,67,327,206,84,491,226,240,239,115,602,372,247,122,529,367,406
|
2258,532,1482,668,1859,868,1679,750,785,1225,501,1191,1229,1267,1796,395,367,44,1490,397,2431,247,792,206,2327,1757,1525,1650,84,372,1063,261,1064,447,1732,571,1199,193,239,602,1202,1205,122,1244,150,1323,67,226,1666,406,896,651,900,327,491,1983,947,240,1211,2181,529,1926,554,1715,115,1127,1293,2121
|
-1.1573411038415724,0.5830937941090167,-0.20577244529591113,0.44163988227236045,-0.5318025210216746,0.26745558495361116,-0.36996889215618123,0.3716218440786248,0.33678607999499527,-0.005472043382106115,0.6187594963253328,0.02826992735684619,-0.005472043382106115,-0.03911004514660509,-0.46734630399467275,0.762668016319278,0.7989629703796846,2.2044216937819225,-0.20577244529591113,0.762668016319278,-2.346883769749101,1.0567387805118416,0.33678607999499527,1.1692816695624557,-1.3985896961877513,-0.4349803471134479,-0.23880560493110126,-0.33732182412727213,1.7124277556268248,0.7989629703796846,0.13012911860860088,1.0195061138420503,0.13012911860860088,0.690462087882705,-0.4025214696779287,0.5475501784669402,0.02826992735684619,1.2070828107445577,1.09411123321543,0.5121274427616084,0.02826992735684619,0.02826992735684619,1.5148945458722094,-0.005472043382106115,1.3597650907486145,-0.0726450035074068,1.8329750185480524,1.1316250081230708,-0.33732182412727213,0.762668016319278,0.26745558495361116,0.4768243999762741,0.26745558495361116,0.8719435308811879,0.6545485118299024,-0.6278088272972961,0.23295871445948424,1.09411123321543,0.02826992735684619,-0.9731613542657431,0.6187594963253328,-0.5638942876356867,0.5830937941090167,-0.36996889215618123,1.554072857182752,0.09606954757438466,-0.03911004514660509,-0.8487597402208368
| 2,466
|
Focal onset seizure
| 18
| 73
| 2.135825
| 0.032694
|
O43776,P27635,O14617,Q96C86,Q9NZ01,Q05639,Q14683,Q9ULM3,P49591,P21359,P43034,P46821,Q96F86,P55011,Q00610,Q9HA77,Q6ZXV5,Q14204
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
91,3,124,67,240,261,239,47,44,80,145,108,226,247,84,99,98,193
|
1182,124,955,1386,91,908,1482,2419,1342,2363,1931,2229,750,629,785,257,80,2014,3,680,597,145,108,2445,44,1017,834,599,247,1527,84,880,372,261,447,2112,571,2428,1199,193,239,1205,98,851,2433,1576,1578,1323,67,1626,226,1666,406,896,1414,376,2000,1172,1947,489,491,1709,99,1983,240,1426,2045,1211,1290,1632,47,952,1292
|
0.02826992735684619,1.4758764855204225,0.19857269655533746,-0.1394094247514785,1.6329179826648552,0.23295871445948424,-0.20577244529591113,-2.0952139505970386,-0.106077830470184,-1.5764361534260334,-0.5958961470236193,-1.0962643994696941,0.3716218440786248,0.4768243999762741,0.33678607999499527,1.0195061138420503,1.752437029840453,-0.691369514566026,5.122983459255199,0.44163988227236045,0.5121274427616084,1.3983135936646063,1.554072857182752,-2.862840977833272,2.2044216937819225,0.16429650233449708,0.30206435300525497,0.5121274427616084,1.0567387805118416,-0.23880560493110126,1.7124277556268248,0.26745558495361116,0.7989629703796846,1.0195061138420503,0.690462087882705,-0.8487597402208368,0.5475501784669402,-2.2635366231677914,0.02826992735684619,1.2070828107445577,1.09411123321543,0.02826992735684619,1.6329179826648552,0.30206435300525497,-2.3745480217142982,-0.2717409991326573,-0.2717409991326573,-0.0726450035074068,1.8329750185480524,-0.3045794640677411,1.1316250081230708,-0.33732182412727213,0.762668016319278,0.26745558495361116,-0.1394094247514785,0.7989629703796846,-0.6596330468559235,0.06211680648946061,-0.5958961470236193,0.6545485118299024,0.6545485118299024,-0.36996889215618123,1.6329179826648552,-0.6278088272972961,1.09411123321543,-0.1394094247514785,-0.7230189299371137,0.02826992735684619,-0.03911004514660509,-0.3045794640677411,2.2044216937819225,0.23295871445948424,-0.03911004514660509
| 2,466
|
Absent septum pellucidum
| 8
| 27
| 2.134815
| 0.032776
|
Q96C86,Q9NZ01,Q9Y617,P49591,P53701,Q15392,Q96F86,Q9NVI1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
67,240,217,44,146,88,226,158
|
1386,2316,1482,1343,1829,750,44,507,146,247,447,1199,1201,88,1205,1244,2194,67,226,406,1852,1034,1983,158,240,1211,217
|
-0.1394094247514785,-1.3686954198284471,-0.20577244529591113,-0.106077830470184,-0.49962010917283683,0.3716218440786248,2.2044216937819225,0.6187594963253328,1.3983135936646063,1.0567387805118416,0.690462087882705,0.02826992735684619,0.02826992735684619,1.672588769694534,0.02826992735684619,-0.005472043382106115,-1.0040573144405394,1.8329750185480524,1.1316250081230708,0.762668016319278,-0.49962010917283683,0.16429650233449708,-0.6278088272972961,1.3213694940336442,1.09411123321543,0.02826992735684619,1.1692816695624557
| 2,466
|
Dna helicase activity
| 13
| 31
| 2.133631
| 0.032873
|
P54132,P46063,Q9H2U1,P33992,P25205,P19447,O14646,Q14839,Q9HCK8,P33993,P33991,P49736,Q13283
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
400,339,328,338,186,256,71,312,152,176,175,282,345
|
1216,71,1445,433,594,256,186,175,338,176,1904,1561,1393,718,339,282,919,400,1065,345,882,312,1695,610,799,893,690,328,152,1927,1820
|
-0.005472043382106115,1.7926187250454313,-0.17264067204748582,0.690462087882705,0.5121274427616084,1.0195061138420503,1.2070828107445577,1.2450300545136346,0.8353876893846488,1.2450300545136346,-0.5638942876356867,-0.2717409991326573,-0.1394094247514785,0.40657274055962805,0.8353876893846488,0.9824117244906789,0.23295871445948424,0.762668016319278,0.13012911860860088,0.8353876893846488,0.26745558495361116,0.9086318760961686,-0.36996889215618123,0.5121274427616084,0.33678607999499527,0.26745558495361116,0.44163988227236045,0.8719435308811879,1.3597650907486145,-0.5638942876356867,-0.46734630399467275
| 2,466
|
Chromosome telomeric region
| 22
| 70
| 2.128578
| 0.033289
|
P54132,P78527,P09874,P39748,Q86W42,P24941,P49736,O60934,P33993,P33991,Q14839,Q96QC0,Q9H2U1,P25205,P05455,Q92769,Q15554,Q6UXN9,P30876,P33992,A6NHR9,Q13416
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
400,135,16,396,289,390,282,278,176,175,312,452,328,186,432,351,209,85,337,338,229,248
|
229,660,667,1184,278,1786,492,1554,432,1223,16,535,1445,433,1644,390,186,1053,914,566,337,175,338,176,396,1148,1961,282,919,400,1491,1061,1872,135,2093,1527,1020,1612,2129,248,2192,882,312,1106,209,1364,935,767,85,1661,289,1165,1883,802,351,893,690,2196,1412,452,1415,945,328,812,2256,949,1332,1951,1127,2244
|
1.09411123321543,0.44163988227236045,0.44163988227236045,0.02826992735684619,0.9824117244906789,-0.46734630399467275,0.6187594963253328,-0.2717409991326573,0.690462087882705,-0.005472043382106115,3.1840096027515767,0.5830937941090167,-0.17264067204748582,0.690462087882705,-0.33732182412727213,0.762668016319278,1.2070828107445577,0.13012911860860088,0.23295871445948424,0.5475501784669402,0.8353876893846488,1.2450300545136346,0.8353876893846488,1.2450300545136346,0.762668016319278,0.06211680648946061,-0.6278088272972961,0.9824117244906789,0.23295871445948424,0.762668016319278,-0.20577244529591113,0.13012911860860088,-0.5318025210216746,1.4370167859616607,-0.8174517203305781,-0.23880560493110126,0.16429650233449708,-0.3045794640677411,-0.8799840708301513,1.0567387805118416,-1.0040573144405394,0.26745558495361116,0.9086318760961686,0.09606954757438466,1.1692816695624557,-0.106077830470184,0.23295871445948424,0.3716218440786248,1.7124277556268248,-0.33732182412727213,0.9824117244906789,0.06211680648946061,-0.5318025210216746,0.33678607999499527,0.8353876893846488,0.26745558495361116,0.44163988227236045,-1.0040573144405394,-0.1394094247514785,0.690462087882705,-0.1394094247514785,0.23295871445948424,0.8719435308811879,0.33678607999499527,-1.1268418278904393,0.23295871445948424,-0.0726450035074068,-0.5958961470236193,0.09606954757438466,-1.0962643994696941
| 2,466
|
Fcgamma receptor fcgr dependent phagocytosis
| 9
| 24
| 2.127882
| 0.033347
|
Q7L576,O15143,Q14185,Q9UQB8,P61160,P28482,P35579,P07900,Q9Y2A7
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
326,6,8,216,371,437,203,334,426
|
704,6,706,1183,1515,334,497,1390,1142,437,203,1195,1757,1909,371,757,1650,8,326,2080,1027,216,426,2069
|
0.40657274055962805,4.116248463498304,0.40657274055962805,0.02826992735684619,-0.23880560493110126,0.8353876893846488,0.6187594963253328,-0.1394094247514785,0.06211680648946061,0.690462087882705,1.1692816695624557,0.02826992735684619,-0.4349803471134479,-0.5638942876356867,0.7989629703796846,0.3716218440786248,-0.33732182412727213,3.8135589893360913,0.8719435308811879,-0.786059355940462,0.16429650233449708,1.1692816695624557,0.7265014927733182,-0.7545819832932289
| 2,466
|
Sister chromatid cohesion
| 8
| 21
| 2.127143
| 0.033408
|
Q9Y6X3,Q9BTE3,Q14807,Q9GZZ1,Q14683,Q29RF7,P39748,Q9NTI5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
174,1,477,407,239,348,396,317
|
1636,1434,1786,1306,1229,1796,396,919,239,477,348,646,851,1883,1244,2225,1,407,317,529,174
|
-0.33732182412727213,-0.17264067204748582,-0.46734630399467275,-0.0726450035074068,-0.005472043382106115,-0.46734630399467275,0.762668016319278,0.23295871445948424,1.09411123321543,0.6545485118299024,0.8353876893846488,0.4768243999762741,0.30206435300525497,-0.5318025210216746,-0.005472043382106115,-1.0656082337385886,5.852267110171458,0.762668016319278,0.9086318760961686,0.6187594963253328,1.2831250541224368
| 2,466
|
Retrognathia
| 18
| 63
| 2.126791
| 0.033437
|
P54132,O60934,O43776,P27635,O14617,Q8N201,Q5T440,Q14683,Q96ST3,P19447,Q9Y617,P51659,Q12797,P53701,Q86W42,Q15392,P38606,Q6NW34
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
400,278,91,3,124,169,265,239,375,256,217,398,284,146,289,88,395,167
|
1294,124,955,1130,1386,91,278,2245,494,1830,1598,964,594,256,436,3,716,1837,395,2125,1606,754,1016,398,1728,146,400,1018,1398,2092,284,421,2021,1402,239,763,88,1279,728,1364,1463,2291,1769,986,265,1407,2234,167,1619,289,169,1281,2082,375,651,1849,1949,2182,952,2152,1127,217,2244
|
-0.0726450035074068,1.4758764855204225,0.19857269655533746,0.06211680648946061,-0.1394094247514785,1.6329179826648552,0.9824117244906789,-1.1268418278904393,0.6187594963253328,-0.49962010917283683,-0.3045794640677411,0.19857269655533746,0.5121274427616084,1.0195061138420503,0.690462087882705,5.122983459255199,0.40657274055962805,-0.49962010917283683,0.762668016319278,-0.8799840708301513,-0.3045794640677411,0.3716218440786248,0.16429650233449708,0.762668016319278,-0.4025214696779287,1.3983135936646063,0.762668016319278,0.16429650233449708,-0.1394094247514785,-0.8174517203305781,0.9824117244906789,0.7265014927733182,-0.691369514566026,-0.1394094247514785,1.09411123321543,0.3716218440786248,1.672588769694534,-0.03911004514660509,0.40657274055962805,-0.106077830470184,-0.17264067204748582,-1.278568131757092,-0.4349803471134479,0.19857269655533746,1.0195061138420503,-0.1394094247514785,-1.0962643994696941,1.2831250541224368,-0.3045794640677411,0.9824117244906789,1.2831250541224368,-0.03911004514660509,-0.786059355940462,0.7989629703796846,0.4768243999762741,-0.49962010917283683,-0.5958961470236193,-0.9731613542657431,0.23295871445948424,-0.9111253589916372,0.09606954757438466,1.1692816695624557,-1.0962643994696941
| 2,466
|
Zinc finger, FYVE/PHD-type [IPR011011]
| 11
| 23
| 2.126048
| 0.033499
|
Q03164,O14964,Q7Z3T8,O75151,Q15075,Q9UPN9,Q9BTC0,Q14839,P29375,Q9NRL2,Q92785
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
542,183,111,12,517,86,315,312,202,525,64
|
183,624,12,1829,202,542,543,844,312,517,111,1942,803,64,2355,941,1538,315,525,1377,1003,86,1336
|
1.2070828107445577,0.4768243999762741,3.4218094448205134,-0.49962010917283683,1.1692816695624557,0.5830937941090167,0.5830937941090167,0.30206435300525497,0.9086318760961686,0.6187594963253328,1.554072857182752,-0.5958961470236193,0.33678607999499527,1.9142203405795986,-1.517439986141119,0.23295871445948424,-0.23880560493110126,0.9086318760961686,0.6187594963253328,-0.106077830470184,0.19857269655533746,1.7124277556268248,-0.0726450035074068
| 2,466
|
Microtubule cytoskeleton regulation
| 9
| 16
| 2.124195
| 0.033654
|
Q7KZI7,P16949,Q9Y281,P40763,Q15691,P46821,O60610,Q16566,Q13464
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
63,218,701,295,643,108,668,97,641
|
668,1223,218,1262,295,108,720,1757,1650,641,643,886,97,63,942,701
|
0.44163988227236045,-0.005472043382106115,1.1316250081230708,-0.03911004514660509,0.9454541305169961,1.554072857182752,0.40657274055962805,-0.4349803471134479,-0.33732182412727213,0.4768243999762741,0.4768243999762741,0.26745558495361116,1.6329179826648552,1.9142203405795986,0.23295871445948424,0.44163988227236045
| 2,466
|
Polysomal ribosome
| 8
| 24
| 2.122275
| 0.033815
|
Q02543,Q02878,P62899,P62917,P62910,Q07020,Q9Y3U8,P62266
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
222,296,109,207,30,343,65,31
|
779,1388,31,1234,2146,1197,109,1454,30,1873,207,2273,1062,402,981,222,296,343,1065,605,575,1739,770,65
|
0.33678607999499527,-0.1394094247514785,2.5043931129264574,-0.005472043382106115,-0.9111253589916372,0.02826992735684619,1.554072857182752,-0.17264067204748582,2.548101157631834,-0.5318025210216746,1.1692816695624557,-1.218107502027458,0.13012911860860088,0.762668016319278,0.19857269655533746,1.1316250081230708,0.9454541305169961,0.8353876893846488,0.13012911860860088,0.5121274427616084,0.5475501784669402,-0.4025214696779287,0.3716218440786248,1.9142203405795986
| 2,466
|
CMGC group
| 6
| 13
| 2.121224
| 0.033903
|
Q96SB4,Q9NYV4,P19784,P28482,P24941,P11802
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
171,68,233,437,390,305
|
1223,305,233,390,1142,437,1935,720,1313,982,513,171,68
|
-0.005472043382106115,0.9086318760961686,1.09411123321543,0.762668016319278,0.06211680648946061,0.690462087882705,-0.5958961470236193,0.40657274055962805,-0.0726450035074068,0.19857269655533746,0.6187594963253328,1.2831250541224368,1.8329750185480524
| 2,466
|
Hypotelorism
| 15
| 32
| 2.116512
| 0.034301
|
Q9NXE4,P55795,O43776,O14617,Q14683,P19447,P26639,Q9Y4A5,P54886,P21359,A5YKK6,Q9NSD9,Q93008,Q7Z6Z7,Q08J23
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
271,401,91,124,239,256,436,115,161,80,383,459,150,155,447
|
383,124,91,594,256,80,436,1681,832,1016,161,401,1608,447,239,516,2148,1364,1971,155,1244,1507,150,1947,2133,856,459,271,813,1588,1955,115
|
0.762668016319278,1.4758764855204225,1.6329179826648552,0.5121274427616084,1.0195061138420503,1.752437029840453,0.690462087882705,-0.36996889215618123,0.30206435300525497,0.16429650233449708,1.2831250541224368,0.762668016319278,-0.3045794640677411,0.690462087882705,1.09411123321543,0.6187594963253328,-0.9111253589916372,-0.106077830470184,-0.6278088272972961,1.3213694940336442,-0.005472043382106115,-0.20577244529591113,1.3597650907486145,-0.5958961470236193,-0.8799840708301513,0.30206435300525497,0.690462087882705,1.0195061138420503,0.33678607999499527,-0.2717409991326573,-0.5958961470236193,1.554072857182752
| 2,466
|
Broad eyebrow
| 6
| 12
| 2.11353
| 0.034555
|
Q12830,Q96ST3,O14646,P28482,P63241,Q6NW34
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
543,375,71,437,27,167
|
71,955,964,595,437,27,880,543,1364,167,1323,375
|
1.7926187250454313,0.19857269655533746,0.19857269655533746,0.5121274427616084,0.690462087882705,2.592032399318675,0.26745558495361116,0.5830937941090167,-0.106077830470184,1.2831250541224368,-0.0726450035074068,0.7989629703796846
| 2,466
|
Erythroid hypoplasia
| 6
| 18
| 2.112706
| 0.034626
|
Q07020,P18077,P62899,P61313,P60866,P08708
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
343,160,109,19,310,281
|
281,160,1606,419,754,1231,310,923,19,1397,1452,756,1102,837,2146,109,1873,343
|
0.9824117244906789,1.2831250541224368,-0.3045794640677411,0.7265014927733182,0.3716218440786248,-0.005472043382106115,0.9086318760961686,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.17264067204748582,0.3716218440786248,0.09606954757438466,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,0.8353876893846488
| 2,466
|
Negative regulation of transcription by rna polymerase ii
| 34
| 112
| 2.111744
| 0.034708
|
P27635,Q8N5F7,Q9HCD5,P51610,P09874,A5YKK6,Q9HCK8,P06733,P26358,P24941,Q93008,Q13618,P09429,Q13547,Q9ULM3,P40763,P55061,P49591,Q9NZM5,P51532,Q92785,Q9UPY3,Q6PD62,Q92769,Q92541,Q9UPN9,P29375,Q8N6R0,Q96ST3,P12270,O14776,Q13416,P26583,P61201
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,139,11,397,16,383,152,386,149,390,150,285,39,164,47,295,45,44,318,308,64,66,210,351,83,86,202,89,375,232,358,248,119,128
|
383,1088,358,1184,1786,669,492,1829,1639,386,39,16,1443,535,232,750,2334,2187,1263,1644,1306,390,391,149,119,3,1723,202,1796,2249,567,295,1055,1961,44,308,1490,397,1683,45,1357,128,1102,1196,1968,1802,1398,1841,2093,446,1313,1527,842,2260,1457,1458,543,1969,2129,844,544,248,164,1843,285,763,1238,2115,644,935,646,767,210,577,1366,578,1165,139,89,1410,2262,83,351,64,150,1079,1978,2132,1118,375,651,1538,2000,1540,586,1034,11,152,1210,1985,318,776,1332,813,1212,47,1038,86,66,659,1383,1040
|
0.762668016319278,0.09606954757438466,0.7989629703796846,0.02826992735684619,-0.46734630399467275,0.44163988227236045,0.6187594963253328,-0.49962010917283683,-0.33732182412727213,0.762668016319278,2.289089293908105,3.1840096027515767,-0.17264067204748582,0.5830937941090167,1.09411123321543,0.3716218440786248,-1.4284107755838522,-1.0040573144405394,-0.03911004514660509,-0.33732182412727213,-0.0726450035074068,0.762668016319278,0.762668016319278,1.3597650907486145,1.5148945458722094,5.122983459255199,-0.4025214696779287,1.1692816695624557,-0.46734630399467275,-1.1268418278904393,0.5475501784669402,0.9454541305169961,0.13012911860860088,-0.6278088272972961,2.2044216937819225,0.9086318760961686,-0.20577244529591113,0.762668016319278,-0.36996889215618123,2.2044216937819225,-0.106077830470184,1.4758764855204225,0.09606954757438466,0.02826992735684619,-0.6278088272972961,-0.46734630399467275,-0.1394094247514785,-0.49962010917283683,-0.8174517203305781,0.690462087882705,-0.0726450035074068,-0.23880560493110126,0.30206435300525497,-1.1573411038415724,-0.17264067204748582,-0.17264067204748582,0.5830937941090167,-0.6278088272972961,-0.8799840708301513,0.30206435300525497,0.5830937941090167,1.0567387805118416,1.2831250541224368,-0.49962010917283683,0.9824117244906789,0.3716218440786248,-0.005472043382106115,-0.8487597402208368,0.4768243999762741,0.23295871445948424,0.4768243999762741,0.3716218440786248,1.1692816695624557,0.5475501784669402,-0.106077830470184,0.5475501784669402,0.06211680648946061,1.4370167859616607,1.672588769694534,-0.1394094247514785,-1.1573411038415724,1.752437029840453,0.8353876893846488,1.9142203405795986,1.3597650907486145,0.13012911860860088,-0.6278088272972961,-0.8799840708301513,0.09606954757438466,0.7989629703796846,0.4768243999762741,-0.23880560493110126,-0.6596330468559235,-0.23880560493110126,0.5475501784669402,0.16429650233449708,3.5671075805179417,1.3597650907486145,0.02826992735684619,-0.6278088272972961,0.9086318760961686,0.3716218440786248,-0.0726450035074068,0.33678607999499527,0.02826992735684619,2.2044216937819225,0.16429650233449708,1.7124277556268248,1.8735081335636863,0.4768243999762741,-0.106077830470184,0.16429650233449708
| 2,466
|
Skin rash
| 7
| 17
| 2.103353
| 0.035435
|
Q7Z2Z2,P19447,P40763,P50747,Q06136,P22681,P14174
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
268,256,295,15,20,51,29
|
29,594,256,2014,51,2381,680,295,15,400,1868,509,20,848,268,733,1822
|
2.548101157631834,0.5121274427616084,1.0195061138420503,-0.691369514566026,2.162387986697736,-1.6935902151553845,0.44163988227236045,0.9454541305169961,3.231128956611099,0.762668016319278,-0.5318025210216746,0.6187594963253328,2.9517648784557937,0.30206435300525497,1.0195061138420503,0.40657274055962805,-0.46734630399467275
| 2,466
|
Axonal transport
| 8
| 17
| 2.096651
| 0.036024
|
O14617,Q9UL25,P43034,Q15554,Q92572,O95239,Q14203,Q14204
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
124,76,145,209,53,243,286,193
|
293,124,1893,243,2420,914,438,145,758,571,2058,286,193,209,53,76,861
|
0.9454541305169961,1.4758764855204225,-0.5638942876356867,1.0567387805118416,-2.0952139505970386,0.23295871445948424,0.690462087882705,1.3983135936646063,0.3716218440786248,0.5475501784669402,-0.7545819832932289,0.9824117244906789,1.2070828107445577,1.1692816695624557,2.1205507147690597,1.7926187250454313,0.30206435300525497
| 2,466
|
Abnormality of the lymph nodes
| 11
| 32
| 2.093154
| 0.036335
|
O15143,Q969U7,P10644,Q9H0U3,P40763,P22681,P33991,P50851,P49327,Q01844,P14174
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
6,102,320,42,295,51,175,56,245,342,29
|
6,866,1789,333,1639,1599,320,29,51,1723,2381,1143,175,295,245,56,1907,1018,342,844,2434,762,1362,1973,1321,102,733,2000,586,42,1586,1125
|
4.116248463498304,0.26745558495361116,-0.46734630399467275,0.8353876893846488,-0.33732182412727213,-0.3045794640677411,0.8719435308811879,2.548101157631834,2.162387986697736,-0.4025214696779287,-1.6935902151553845,0.06211680648946061,1.2450300545136346,0.9454541305169961,1.0567387805118416,2.0789072337159866,-0.5638942876356867,0.16429650233449708,0.8353876893846488,0.30206435300525497,-2.4021538137229657,0.3716218440786248,-0.106077830470184,-0.6278088272972961,-0.0726450035074068,1.5934133472710452,0.40657274055962805,-0.6596330468559235,0.5475501784669402,2.289089293908105,-0.2717409991326573,0.09606954757438466
| 2,466
|
Abnormal fingertip morphology
| 10
| 22
| 2.090307
| 0.03659
|
P55795,Q12830,O14646,P46821,P55011,P50851,Q9BZK7,Q7Z6Z7,P15924,P62266
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
401,543,71,108,247,56,586,155,306,31
|
1294,71,2245,1638,912,306,565,108,56,247,401,31,543,1360,1076,1619,155,1281,1947,586,856,1953
|
-0.0726450035074068,1.7926187250454313,-1.1268418278904393,-0.33732182412727213,0.23295871445948424,0.9086318760961686,0.5475501784669402,1.554072857182752,2.0789072337159866,1.0567387805118416,0.762668016319278,2.5043931129264574,0.5830937941090167,-0.106077830470184,0.13012911860860088,-0.3045794640677411,1.3213694940336442,-0.03911004514660509,-0.5958961470236193,0.5475501784669402,0.30206435300525497,-0.5958961470236193
| 2,466
|
Abnormality of the thenar eminence
| 6
| 17
| 2.089123
| 0.036697
|
Q07020,P18077,P62899,P61313,P60866,P08708
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
343,160,109,19,310,281
|
281,160,1606,419,754,1231,310,923,19,1397,1452,756,837,2146,109,1873,343
|
0.9824117244906789,1.2831250541224368,-0.3045794640677411,0.7265014927733182,0.3716218440786248,-0.005472043382106115,0.9086318760961686,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.17264067204748582,0.3716218440786248,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,0.8353876893846488
| 2,466
|
Dna dependent dna replication
| 19
| 60
| 2.085116
| 0.037059
|
Q07864,Q9BTE3,P54132,P39748,Q7Z7L1,P49736,O60934,Q92547,P33993,P33991,P25205,Q15554,P46063,P49427,P33992,Q96T60,Q9Y2S7,Q13416,O95785
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,1,400,396,156,282,278,33,176,175,186,209,339,93,338,376,382,248,361
|
667,278,1006,1483,2245,1828,361,964,535,2392,1052,390,186,1053,566,175,338,176,1904,1561,567,396,1393,718,339,93,598,282,635,919,400,1527,1761,130,248,882,209,1696,156,1661,990,33,690,1978,2196,2277,376,1921,1,1081,2394,655,2405,525,1543,1428,1712,382,1592,2244
|
0.44163988227236045,0.9824117244906789,0.16429650233449708,-0.20577244529591113,-1.1268418278904393,-0.49962010917283683,0.7989629703796846,0.19857269655533746,0.5830937941090167,-1.7807372065255946,0.13012911860860088,0.762668016319278,1.2070828107445577,0.13012911860860088,0.5475501784669402,1.2450300545136346,0.8353876893846488,1.2450300545136346,-0.5638942876356867,-0.2717409991326573,0.5475501784669402,0.762668016319278,-0.1394094247514785,0.40657274055962805,0.8353876893846488,1.6329179826648552,0.5121274427616084,0.9824117244906789,0.4768243999762741,0.23295871445948424,0.762668016319278,-0.23880560493110126,-0.4349803471134479,1.4758764855204225,1.0567387805118416,0.26745558495361116,1.1692816695624557,-0.36996889215618123,1.3213694940336442,-0.33732182412727213,0.19857269655533746,2.4609050013050613,0.44163988227236045,-0.6278088272972961,-1.0040573144405394,-1.218107502027458,0.7989629703796846,-0.5638942876356867,5.852267110171458,0.13012911860860088,-1.7807372065255946,0.4768243999762741,-1.924649980401603,0.6187594963253328,-0.23880560493110126,-0.1394094247514785,-0.36996889215618123,0.7989629703796846,-0.2717409991326573,-1.0962643994696941
| 2,466
|
Gastroesophageal reflux
| 43
| 97
| 2.078857
| 0.03763
|
P54132,P55795,P27635,O95319,Q05639,P21333,P24928,P51571,Q93008,P63241,P38606,P78347,Q6NW34,Q03164,Q93009,P49588,P53992,Q15436,P54886,O00203,Q7L0Y3,Q9NSD9,P15924,Q14204,Q12756,Q9Y4P3,P29372,P55265,P53597,P28482,Q8NBU5,Q00610,Q6ZXV5,P18583,Q14683,Q96T58,P46821,P55011,Q01105,P12235,Q9UQE7,P35658,P42704
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
400,401,3,493,261,257,258,507,150,27,395,420,167,542,425,538,540,43,161,293,181,459,306,193,571,70,322,570,443,437,82,84,98,595,239,651,108,247,372,363,529,366,367
|
293,1257,662,1386,1636,1859,1342,1343,493,1638,1829,1931,1790,363,2186,306,1094,595,785,257,2089,258,3,437,322,1681,1561,366,916,2015,395,1269,367,108,538,1934,507,1490,1728,443,540,400,161,247,570,401,2076,1526,27,420,2320,84,372,1568,542,261,571,1021,193,239,848,2059,1202,43,1364,1407,646,2234,167,1076,98,181,851,2063,1244,82,1077,150,425,1625,1775,1027,735,1666,651,1672,1034,459,1426,2137,813,1122,2182,1003,529,70,2244
|
0.9454541305169961,-0.03911004514660509,0.44163988227236045,-0.1394094247514785,-0.33732182412727213,-0.5318025210216746,-0.106077830470184,-0.106077830470184,0.6187594963253328,-0.33732182412727213,-0.49962010917283683,-0.5958961470236193,-0.46734630399467275,0.7989629703796846,-1.0040573144405394,0.9086318760961686,0.09606954757438466,0.5121274427616084,0.33678607999499527,1.0195061138420503,-0.8174517203305781,1.0195061138420503,5.122983459255199,0.690462087882705,0.8719435308811879,-0.36996889215618123,-0.2717409991326573,0.7989629703796846,0.23295871445948424,-0.691369514566026,0.762668016319278,-0.03911004514660509,0.7989629703796846,1.554072857182752,0.5830937941090167,-0.5958961470236193,0.6187594963253328,-0.20577244529591113,-0.4025214696779287,0.690462087882705,0.5830937941090167,0.762668016319278,1.2831250541224368,1.0567387805118416,0.5475501784669402,0.762668016319278,-0.786059355940462,-0.23880560493110126,2.592032399318675,0.7265014927733182,-1.3686954198284471,1.7124277556268248,0.7989629703796846,-0.2717409991326573,0.5830937941090167,1.0195061138420503,0.5475501784669402,0.16429650233449708,1.2070828107445577,1.09411123321543,0.30206435300525497,-0.7545819832932289,0.02826992735684619,2.246654540588567,-0.106077830470184,-0.1394094247514785,0.4768243999762741,-1.0962643994696941,1.2831250541224368,0.13012911860860088,1.6329179826648552,1.2450300545136346,0.30206435300525497,-0.7545819832932289,-0.005472043382106115,1.752437029840453,0.13012911860860088,1.3597650907486145,0.7265014927733182,-0.3045794640677411,-0.4349803471134479,0.16429650233449708,0.40657274055962805,-0.33732182412727213,0.4768243999762741,-0.33732182412727213,0.16429650233449708,0.690462087882705,-0.1394094247514785,-0.8799840708301513,0.33678607999499527,0.09606954757438466,-0.9731613542657431,0.19857269655533746,0.6187594963253328,1.8329750185480524,-1.0962643994696941
| 2,466
|
Translation regulation
| 13
| 41
| 2.076387
| 0.037858
|
P27635,P07814,Q9H2U1,Q9Y6M1,O43432,Q9Y450,P40429,Q8TEQ6,Q92616,Q9UQ80,A5YKK6,Q9BX40,Q04637
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
3,126,328,142,90,272,418,449,213,381,383,199,129
|
383,864,1216,90,781,869,1556,126,674,1051,3,2125,418,1101,838,445,1841,129,1065,2020,1496,796,605,449,992,770,213,1117,1813,1703,199,809,585,944,328,775,776,381,272,905,142
|
0.762668016319278,0.26745558495361116,-0.005472043382106115,1.6329179826648552,0.33678607999499527,0.26745558495361116,-0.2717409991326573,1.4758764855204225,0.44163988227236045,0.13012911860860088,5.122983459255199,-0.8799840708301513,0.7265014927733182,0.09606954757438466,0.30206435300525497,0.690462087882705,-0.49962010917283683,1.4758764855204225,0.13012911860860088,-0.691369514566026,-0.20577244529591113,0.33678607999499527,0.5121274427616084,0.690462087882705,0.19857269655533746,0.3716218440786248,1.1692816695624557,0.09606954757438466,-0.46734630399467275,-0.36996889215618123,1.2070828107445577,0.33678607999499527,0.5475501784669402,0.23295871445948424,0.8719435308811879,0.3716218440786248,0.3716218440786248,0.7989629703796846,1.0195061138420503,0.26745558495361116,1.4370167859616607
| 2,466
|
Coarctation of aorta
| 13
| 37
| 2.069814
| 0.03847
|
P42766,Q07020,Q9Y4A5,P18077,P53597,P21359,P62899,P61313,P55263,Q14839,P60866,P08708,Q69YQ0
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
419,343,115,160,443,80,109,19,206,312,310,281,196
|
1132,1434,281,160,629,80,1015,1606,419,754,1231,443,206,310,923,19,1397,1452,1061,756,837,2146,109,1873,1493,474,343,312,1362,196,1076,1244,1034,2137,2182,115,905
|
0.06211680648946061,-0.17264067204748582,0.9824117244906789,1.2831250541224368,0.4768243999762741,1.752437029840453,0.16429650233449708,-0.3045794640677411,0.7265014927733182,0.3716218440786248,-0.005472043382106115,0.690462087882705,1.1692816695624557,0.9086318760961686,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.17264067204748582,0.13012911860860088,0.3716218440786248,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,-0.20577244529591113,0.6545485118299024,0.8353876893846488,0.9086318760961686,-0.106077830470184,1.2070828107445577,0.13012911860860088,-0.005472043382106115,0.16429650233449708,-0.8799840708301513,-0.9731613542657431,1.554072857182752,0.26745558495361116
| 2,466
|
Protein export from nucleus
| 8
| 22
| 2.058644
| 0.039528
|
Q92688,O14980,Q06124,P12270,Q9H6Z4,Q9HAV4,P46060,P35658
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
424,427,474,232,408,148,368,366
|
427,1515,232,1262,1723,366,1351,368,720,1099,472,1871,1104,982,474,424,1030,408,148,1083,1587,1213
|
0.690462087882705,-0.23880560493110126,1.09411123321543,-0.03911004514660509,-0.4025214696779287,0.7989629703796846,-0.106077830470184,0.7989629703796846,0.40657274055962805,0.09606954757438466,0.6545485118299024,-0.5318025210216746,0.09606954757438466,0.19857269655533746,0.6545485118299024,0.7265014927733182,0.16429650233449708,0.762668016319278,1.3983135936646063,0.13012911860860088,-0.2717409991326573,0.02826992735684619
| 2,466
|
Dendritic spine morphogenesis
| 7
| 15
| 2.057324
| 0.039655
|
Q12756,Q9H2U1,Q9UQB8,P61160,P43034,Q15334,Q96HC4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
571,328,216,371,145,179,251
|
625,1390,145,1757,371,982,1063,571,761,179,1107,251,328,1123,216
|
0.4768243999762741,-0.1394094247514785,1.3983135936646063,-0.4349803471134479,0.7989629703796846,0.19857269655533746,0.13012911860860088,0.5475501784669402,0.3716218440786248,1.2450300545136346,0.09606954757438466,1.0567387805118416,0.8719435308811879,0.09606954757438466,1.1692816695624557
| 2,466
|
Ribosomal large subunit assembly
| 12
| 22
| 2.054971
| 0.039882
|
Q9NU22,P27635,Q9H7B2,Q9NYY8,Q14137,P46087,P39023,Q02878,Q9NZM5,Q9UKD2,Q9NQ55,Q7L2E3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
697,3,103,409,346,504,440,296,318,527,619,686
|
670,3,440,504,754,879,1873,2273,1062,296,346,1072,686,1282,1510,103,619,697,902,409,318,527
|
0.44163988227236045,5.122983459255199,0.690462087882705,0.6187594963253328,0.3716218440786248,0.26745558495361116,-0.5318025210216746,-1.218107502027458,0.13012911860860088,0.9454541305169961,0.8353876893846488,0.13012911860860088,0.44163988227236045,-0.03911004514660509,-0.20577244529591113,1.5934133472710452,0.5121274427616084,0.44163988227236045,0.26745558495361116,0.762668016319278,0.9086318760961686,0.6187594963253328
| 2,466
|
Abnormal paranasal sinus morphology
| 9
| 18
| 2.049681
| 0.040396
|
O60934,Q7Z2Z2,P10644,Q9H0U3,P21333,Q86Y56,P21359,A6NHR9,P50851
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
278,268,320,42,257,211,80,229,56
|
229,2281,278,1789,333,783,320,257,80,2381,56,1684,509,2038,268,211,42,1822
|
1.09411123321543,-1.2483757586357453,0.9824117244906789,-0.46734630399467275,0.8353876893846488,0.33678607999499527,0.8719435308811879,1.0195061138420503,1.752437029840453,-1.6935902151553845,2.0789072337159866,-0.36996889215618123,0.6187594963253328,-0.7230189299371137,1.0195061138420503,1.1692816695624557,2.289089293908105,-0.46734630399467275
| 2,466
|
Tp53 regulates transcription of dna repair genes
| 7
| 20
| 2.045874
| 0.040769
|
Q9NYV4,P19447,P24928,Q08945,Q9Y5B9,Q14676,Q9NVI1
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
68,256,258,178,273,195,158
|
1088,746,1639,594,2230,256,825,258,337,1148,1453,1566,178,195,933,1766,1915,158,68,273
|
0.09606954757438466,0.3716218440786248,-0.33732182412727213,0.5121274427616084,-1.0962643994696941,1.0195061138420503,0.30206435300525497,1.0195061138420503,0.8353876893846488,0.06211680648946061,-0.17264067204748582,-0.2717409991326573,1.2450300545136346,1.2070828107445577,0.23295871445948424,-0.4349803471134479,-0.5638942876356867,1.3213694940336442,1.8329750185480524,1.0195061138420503
| 2,466
|
Regulation of dendritic spine development
| 6
| 11
| 2.045012
| 0.040854
|
Q9H2U1,Q92769,Q9UQB8,P61160,P43034,P78344
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
328,351,216,371,145,445
|
145,371,445,1063,571,761,1107,351,328,1123,216
|
1.3983135936646063,0.7989629703796846,0.690462087882705,0.13012911860860088,0.5475501784669402,0.3716218440786248,0.09606954757438466,0.8353876893846488,0.8719435308811879,0.09606954757438466,1.1692816695624557
| 2,466
|
Base excision repair
| 7
| 11
| 2.045011
| 0.040854
|
Q07864,P12004,P29372,Q96T60,P28340,P39748,Q7Z6Z7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,535,322,376,566,396,155
|
535,1051,1053,914,566,322,396,635,130,155,376
|
0.5830937941090167,0.13012911860860088,0.13012911860860088,0.23295871445948424,0.5475501784669402,0.8719435308811879,0.762668016319278,0.4768243999762741,1.4758764855204225,1.3213694940336442,0.7989629703796846
| 2,466
|
Trna aminoacylation
| 15
| 35
| 2.043443
| 0.041009
|
P23381,P26640,O43776,P07814,P49588,P26639,Q9HA77,Q15046,P49591,P14868,Q9NSD9,Q9P2J5,Q9BW92,Q5JPH6,Q9NP81
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
435,127,91,126,538,436,99,347,44,389,459,462,552,28,618
|
2008,91,126,389,435,436,127,1270,719,832,538,1058,44,599,1018,835,1199,928,932,347,1498,28,1616,1533,1242,552,1815,99,618,459,1424,462,1632,702,2068
|
-0.691369514566026,1.6329179826648552,1.4758764855204225,0.762668016319278,0.690462087882705,0.690462087882705,1.4758764855204225,-0.03911004514660509,0.40657274055962805,0.30206435300525497,0.5830937941090167,0.13012911860860088,2.2044216937819225,0.5121274427616084,0.16429650233449708,0.30206435300525497,0.02826992735684619,0.23295871445948424,0.23295871445948424,0.8353876893846488,-0.20577244529591113,2.592032399318675,-0.3045794640677411,-0.23880560493110126,-0.005472043382106115,0.5830937941090167,-0.46734630399467275,1.6329179826648552,0.5121274427616084,0.690462087882705,-0.1394094247514785,0.690462087882705,-0.3045794640677411,0.44163988227236045,-0.7545819832932289
| 2,466
|
Abnormal pulmonary valve physiology
| 14
| 32
| 2.043148
| 0.041038
|
Q06124,Q9Y4P3,Q6PGP7,P54886,P21359,P36507,P55263,O95169,Q13618,Q9UQE7,P00813,P15924,P78347,O75306
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
474,70,325,161,80,177,206,360,285,529,333,306,420,304
|
1294,955,1956,1636,1859,304,360,1222,1638,333,306,80,1561,177,161,206,1757,1397,1061,420,1493,474,543,285,2059,325,1368,2041,1003,1479,529,70
|
-0.0726450035074068,0.19857269655533746,-0.6278088272972961,-0.33732182412727213,-0.5318025210216746,0.9086318760961686,0.7989629703796846,-0.005472043382106115,-0.33732182412727213,0.8353876893846488,0.9086318760961686,1.752437029840453,-0.2717409991326573,1.2450300545136346,1.2831250541224368,1.1692816695624557,-0.4349803471134479,-0.1394094247514785,0.13012911860860088,0.7265014927733182,-0.20577244529591113,0.6545485118299024,0.5830937941090167,0.9824117244906789,-0.7545819832932289,0.8719435308811879,-0.106077830470184,-0.7230189299371137,0.19857269655533746,-0.17264067204748582,0.6187594963253328,1.8329750185480524
| 2,466
|
Gastrointestinal carcinoma
| 8
| 25
| 2.041977
| 0.041154
|
Q07864,P52701,Q07020,P18077,P62899,P61313,P60866,P08708
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,101,343,160,109,19,310,281
|
1434,1639,281,160,566,1796,1606,419,1148,754,1231,101,310,923,19,1397,1452,756,837,2146,109,1873,1492,343,130
|
-0.17264067204748582,-0.33732182412727213,0.9824117244906789,1.2831250541224368,0.5475501784669402,-0.46734630399467275,-0.3045794640677411,0.7265014927733182,0.06211680648946061,0.3716218440786248,-0.005472043382106115,1.5934133472710452,0.9086318760961686,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.17264067204748582,0.3716218440786248,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,-0.20577244529591113,0.8353876893846488,1.4758764855204225
| 2,466
|
non-receptor serine/threonine protein kinase
| 11
| 31
| 2.035768
| 0.041774
|
Q7KZI7,Q96SB4,Q9NYV4,P78527,Q9Y4A5,P28482,P36507,P24941,Q16513,Q16566,P11802
|
Functions
|
Panther Protein class
|
panther_protein_class
|
63,171,68,135,115,437,177,390,223,97,305
|
1434,1136,1223,305,1262,714,390,1142,437,177,597,1647,1935,720,1965,135,1313,982,1493,1764,641,513,223,97,63,1409,1848,171,898,68,115
|
-0.17264067204748582,0.06211680648946061,-0.005472043382106115,0.9086318760961686,-0.03911004514660509,0.40657274055962805,0.762668016319278,0.06211680648946061,0.690462087882705,1.2450300545136346,0.5121274427616084,-0.33732182412727213,-0.5958961470236193,0.40657274055962805,-0.6278088272972961,1.4370167859616607,-0.0726450035074068,0.19857269655533746,-0.20577244529591113,-0.4349803471134479,0.4768243999762741,0.6187594963253328,1.1316250081230708,1.6329179826648552,1.9142203405795986,-0.1394094247514785,-0.49962010917283683,1.2831250541224368,0.26745558495361116,1.8329750185480524,1.554072857182752
| 2,466
|
Gtpase activator activity
| 13
| 33
| 2.034308
| 0.041921
|
O60343,Q8TC07,Q9HCU5,Q14185,Q4KMP7,Q15436,Q9H6Z4,P21359,P46940,Q15334,Q9P035,P46060,Q15437
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
125,170,141,8,324,43,408,80,260,179,353,368,96
|
1182,125,80,1267,2055,368,260,569,1355,1059,1492,1568,8,884,516,179,43,96,324,1941,1206,1111,170,900,2404,856,695,408,141,353,462,1382,2400
|
0.02826992735684619,1.4758764855204225,1.752437029840453,-0.03911004514660509,-0.7545819832932289,0.7989629703796846,1.0195061138420503,0.5475501784669402,-0.106077830470184,0.13012911860860088,-0.20577244529591113,-0.2717409991326573,3.8135589893360913,0.26745558495361116,0.6187594963253328,1.2450300545136346,2.246654540588567,1.6329179826648552,0.8719435308811879,-0.5958961470236193,0.02826992735684619,0.09606954757438466,1.2831250541224368,0.26745558495361116,-1.924649980401603,0.30206435300525497,0.44163988227236045,0.762668016319278,1.4370167859616607,0.8353876893846488,0.690462087882705,-0.106077830470184,-1.8959985840823472
| 2,466
|
Partial duplication of the phalanx of hand
| 6
| 18
| 2.033437
| 0.042008
|
Q07020,P18077,P62899,P61313,P60866,P08708
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
343,160,109,19,310,281
|
281,160,1606,419,754,1231,1608,310,923,19,1397,1452,756,837,2146,109,1873,343
|
0.9824117244906789,1.2831250541224368,-0.3045794640677411,0.7265014927733182,0.3716218440786248,-0.005472043382106115,-0.3045794640677411,0.9086318760961686,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.17264067204748582,0.3716218440786248,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,0.8353876893846488
| 2,466
|
Cellular response to insulin stimulus
| 11
| 41
| 2.028296
| 0.04253
|
Q7L576,O60343,Q9BZF1,P07814,P48506,Q9HCD5,P78527,Q9UQB8,P09874,Q92572,P11802
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
326,125,35,126,237,11,135,216,16,53,305
|
704,331,819,125,1435,2270,1832,126,16,305,674,872,470,1011,1305,1055,1097,237,1935,720,1150,835,1687,2143,1526,757,135,474,1159,2117,1408,326,2194,53,649,1170,1079,35,11,216,2069
|
0.40657274055962805,0.8353876893846488,0.30206435300525497,1.4758764855204225,-0.17264067204748582,-1.218107502027458,-0.49962010917283683,1.4758764855204225,3.1840096027515767,0.9086318760961686,0.44163988227236045,0.26745558495361116,0.6545485118299024,0.16429650233449708,-0.0726450035074068,0.13012911860860088,0.09606954757438466,1.09411123321543,-0.5958961470236193,0.40657274055962805,0.06211680648946061,0.30206435300525497,-0.36996889215618123,-0.9111253589916372,-0.23880560493110126,0.3716218440786248,1.4370167859616607,0.6545485118299024,0.06211680648946061,-0.8487597402208368,-0.1394094247514785,0.8719435308811879,-1.0040573144405394,2.1205507147690597,0.4768243999762741,0.06211680648946061,0.13012911860860088,2.417633637154997,3.5671075805179417,1.1692816695624557,-0.7545819832932289
| 2,466
|
Dna strand elongation
| 10
| 19
| 2.024622
| 0.042906
|
P33992,P12004,P25205,P28340,P35251,Q9Y2S7,P39748,P33993,P33991,P49736
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
338,535,186,566,567,382,396,176,175,282
|
964,535,186,1053,566,175,338,176,1904,1561,567,396,1393,718,598,282,882,1921,382
|
0.19857269655533746,0.5830937941090167,1.2070828107445577,0.13012911860860088,0.5475501784669402,1.2450300545136346,0.8353876893846488,1.2450300545136346,-0.5638942876356867,-0.2717409991326573,0.5475501784669402,0.762668016319278,-0.1394094247514785,0.40657274055962805,0.5121274427616084,0.9824117244906789,0.26745558495361116,-0.5638942876356867,0.7989629703796846
| 2,466
|
Duplication of thumb phalanx
| 6
| 19
| 2.020684
| 0.043312
|
P60866,P18077,P62899,P61313,Q07020,P08708
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
310,160,109,19,343,281
|
281,160,1487,1606,419,754,1231,1608,310,923,19,1397,1452,756,837,2146,109,1873,343
|
0.9824117244906789,1.2831250541224368,-0.20577244529591113,-0.3045794640677411,0.7265014927733182,0.3716218440786248,-0.005472043382106115,-0.3045794640677411,0.9086318760961686,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.17264067204748582,0.3716218440786248,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,0.8353876893846488
| 2,466
|
Interictal eeg abnormality
| 29
| 73
| 2.020446
| 0.043337
|
P27635,O95319,Q05639,P51610,P43034,Q13618,P38606,O60701,P49588,P08243,P49591,Q13813,Q08J23,Q96C86,Q9Y617,P21359,Q8NBU5,Q00610,Q9HA77,Q96F86,Q8IYI6,Q9NZ01,Q14683,Q96T60,Q5H8A4,P46821,P55011,P42704,Q96N66
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
3,493,261,397,145,285,395,277,538,294,44,573,447,67,217,80,82,84,99,226,481,240,239,376,518,108,247,367,406
|
1386,1482,277,2358,2419,493,782,2122,294,1790,2229,2088,750,80,3,1265,916,395,1147,367,145,1488,108,2445,538,44,1490,397,1728,247,1526,84,880,1063,261,447,571,1199,928,285,573,1571,2202,239,1463,1203,518,1025,1205,2433,481,82,1625,67,1626,1027,226,406,896,1414,376,2179,1709,99,1424,1983,240,2045,1211,1290,813,1179,217
|
-0.1394094247514785,-0.20577244529591113,0.9824117244906789,-1.546973401962453,-2.0952139505970386,0.6187594963253328,0.33678607999499527,-0.8799840708301513,0.9454541305169961,-0.46734630399467275,-1.0962643994696941,-0.8174517203305781,0.3716218440786248,1.752437029840453,5.122983459255199,-0.03911004514660509,0.23295871445948424,0.762668016319278,0.06211680648946061,0.7989629703796846,1.3983135936646063,-0.20577244529591113,1.554072857182752,-2.862840977833272,0.5830937941090167,2.2044216937819225,-0.20577244529591113,0.762668016319278,-0.4025214696779287,1.0567387805118416,-0.23880560493110126,1.7124277556268248,0.26745558495361116,0.13012911860860088,1.0195061138420503,0.690462087882705,0.5475501784669402,0.02826992735684619,0.23295871445948424,0.9824117244906789,0.5475501784669402,-0.2717409991326573,-1.034872738573468,1.09411123321543,-0.17264067204748582,0.02826992735684619,0.6187594963253328,0.16429650233449708,0.02826992735684619,-2.3745480217142982,0.6545485118299024,1.752437029840453,-0.3045794640677411,1.8329750185480524,-0.3045794640677411,0.16429650233449708,1.1316250081230708,0.762668016319278,0.26745558495361116,-0.1394094247514785,0.7989629703796846,-0.9731613542657431,-0.36996889215618123,1.6329179826648552,-0.1394094247514785,-0.6278088272972961,1.09411123321543,-0.7230189299371137,0.02826992735684619,-0.03911004514660509,0.33678607999499527,0.06211680648946061,1.1692816695624557
| 2,466
|
General transcription initiation factor binding
| 6
| 15
| 2.019599
| 0.043425
|
Q86VP6,P42345,O14981,Q9ULM3,Q9Y2X3,P22087
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
374,597,7,47,622,563
|
7,1130,1639,563,597,601,1153,842,1361,374,1328,47,1927,1820,622
|
3.963965887756176,0.06211680648946061,-0.33732182412727213,0.5475501784669402,0.5121274427616084,0.5121274427616084,0.06211680648946061,0.30206435300525497,-0.106077830470184,0.7989629703796846,-0.0726450035074068,2.2044216937819225,-0.5638942876356867,-0.46734630399467275,0.5121274427616084
| 2,466
|
Metabolism of vitamins and cofactors
| 11
| 36
| 2.01097
| 0.044329
|
Q96RQ3,Q9H2D1,P11586,Q9NVE7,P50747,Q13085,P11498,P05165,O00763,P29375,P49327
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
34,38,185,303,15,17,18,52,116,202,245
|
116,2158,962,1137,52,2267,334,2229,18,185,676,202,439,1392,1487,877,1097,245,15,2111,17,889,1163,2433,1166,2222,1026,2027,34,1327,38,1922,810,1176,303,1953
|
1.5148945458722094,-0.9421842433017042,0.19857269655533746,0.06211680648946061,2.1205507147690597,-1.1877628050053848,0.8353876893846488,-1.0962643994696941,2.9517648784557937,1.2070828107445577,0.44163988227236045,1.1692816695624557,0.690462087882705,-0.1394094247514785,-0.20577244529591113,0.26745558495361116,0.09606954757438466,1.0567387805118416,3.231128956611099,-0.8487597402208368,3.090438391144676,0.26745558495361116,0.06211680648946061,-2.3745480217142982,0.06211680648946061,-1.0656082337385886,0.16429650233449708,-0.691369514566026,2.4609050013050613,-0.0726450035074068,2.331728784771444,-0.5638942876356867,0.33678607999499527,0.06211680648946061,0.9454541305169961,-0.5958961470236193
| 2,466
|
Immunodeficiency
| 20
| 49
| 2.006953
| 0.044755
|
Q07864,Q7Z2Z2,O14617,P78527,P61011,P14174,Q9H0U3,Q9Y4L1,P50851,P11586,Q6PGP7,O14646,P46109,P28482,P00813,Q15437,P48506,Q9NRZ9,Q13620,P35573
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,268,124,135,509,29,42,319,56,185,325,71,441,437,333,96,237,379,514,107
|
2281,124,71,1434,626,1343,1638,1829,1789,333,1750,1599,2246,185,29,675,1095,2014,2089,676,437,107,1055,441,237,56,540,1868,1757,509,135,2019,130,514,96,642,1500,325,1696,268,1077,1775,899,42,379,812,1782,1822,319
|
-1.2483757586357453,1.4758764855204225,1.7926187250454313,-0.17264067204748582,0.4768243999762741,-0.106077830470184,-0.33732182412727213,-0.49962010917283683,-0.46734630399467275,0.8353876893846488,-0.4349803471134479,-0.3045794640677411,-1.1268418278904393,1.2070828107445577,2.548101157631834,0.44163988227236045,0.09606954757438466,-0.691369514566026,-0.8174517203305781,0.44163988227236045,0.690462087882705,1.554072857182752,0.13012911860860088,0.690462087882705,1.09411123321543,2.0789072337159866,0.5830937941090167,-0.5318025210216746,-0.4349803471134479,0.6187594963253328,1.4370167859616607,-0.691369514566026,1.4758764855204225,0.6187594963253328,1.6329179826648552,0.4768243999762741,-0.20577244529591113,0.8719435308811879,-0.36996889215618123,1.0195061138420503,0.13012911860860088,-0.4349803471134479,0.26745558495361116,2.289089293908105,0.7989629703796846,0.33678607999499527,-0.4349803471134479,-0.46734630399467275,0.9086318760961686
| 2,466
|
Ubiquitin like protein transferase activity
| 11
| 42
| 2.006305
| 0.044824
|
Q9ULT8,Q15386,P49427,Q7Z6E9,Q9NR09,Q5VTR2,P22681,Q9UPN9,O95376,Q7Z6Z7,Q14527
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
32,62,93,168,46,110,51,86,244,155,194
|
624,909,959,910,244,499,51,93,569,1757,1758,2268,1839,925,1063,844,1655,285,795,194,1360,62,1573,1504,110,168,155,2353,1698,771,735,1538,2000,855,491,46,1124,32,1713,86,2170,1634
|
0.4768243999762741,0.23295871445948424,0.19857269655533746,0.23295871445948424,1.0567387805118416,0.6187594963253328,2.162387986697736,1.6329179826648552,0.5475501784669402,-0.4349803471134479,-0.4349803471134479,-1.1877628050053848,-0.49962010917283683,0.23295871445948424,0.13012911860860088,0.30206435300525497,-0.33732182412727213,0.9824117244906789,0.33678607999499527,1.2070828107445577,-0.106077830470184,1.9142203405795986,-0.2717409991326573,-0.20577244529591113,1.554072857182752,1.2831250541224368,1.3213694940336442,-1.517439986141119,-0.36996889215618123,0.3716218440786248,0.40657274055962805,-0.23880560493110126,-0.6596330468559235,0.30206435300525497,0.6545485118299024,2.2044216937819225,0.09606954757438466,2.5043931129264574,-0.36996889215618123,1.7124277556268248,-0.9421842433017042,-0.3045794640677411
| 2,466
|
Abnormality of the pulmonary vasculature
| 8
| 31
| 2.00619
| 0.044836
|
P27635,Q9Y4P3,Q14683,Q86Y56,P55011,P22681,Q15392,Q7Z6Z7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
3,70,239,211,247,51,88,155
|
1294,1516,912,1830,964,51,565,3,1561,1907,247,1684,1757,1061,756,420,474,543,1360,239,2059,88,642,325,1619,155,211,1947,813,1003,70
|
-0.0726450035074068,-0.23880560493110126,0.23295871445948424,-0.49962010917283683,0.19857269655533746,2.162387986697736,0.5475501784669402,5.122983459255199,-0.2717409991326573,-0.5638942876356867,1.0567387805118416,-0.36996889215618123,-0.4349803471134479,0.13012911860860088,0.3716218440786248,0.7265014927733182,0.6545485118299024,0.5830937941090167,-0.106077830470184,1.09411123321543,-0.7545819832932289,1.672588769694534,0.4768243999762741,0.8719435308811879,-0.3045794640677411,1.3213694940336442,1.1692816695624557,-0.5958961470236193,0.33678607999499527,0.19857269655533746,1.8329750185480524
| 2,466
|
Microtubule based movement
| 21
| 61
| 2.004751
| 0.04499
|
Q9Y6G9,O14617,P43034,Q14203,P62820,Q86UP2,O00203,Q8TD16,Q92572,Q14204,Q9UL25,P33176,Q86Y56,Q15554,P27816,Q14807,P61160,P46821,O95239,Q15154,P42704
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
531,124,145,286,283,422,293,579,53,193,76,438,211,209,336,477,371,108,243,264,367
|
2367,2154,293,124,1893,1135,1221,1222,243,2420,672,2087,1519,1306,1140,914,336,438,1145,367,145,108,921,1684,1757,1909,371,283,1398,1527,842,1400,758,571,1201,2058,286,193,1236,477,1275,264,1878,209,2094,730,422,211,1505,1367,1369,579,1665,53,942,1779,76,861,1086,1716,531
|
-1.6058287296638494,-0.9421842433017042,0.9454541305169961,1.4758764855204225,-0.5638942876356867,0.06211680648946061,-0.005472043382106115,-0.005472043382106115,1.0567387805118416,-2.0952139505970386,0.44163988227236045,-0.8174517203305781,-0.23880560493110126,-0.0726450035074068,0.06211680648946061,0.23295871445948424,0.8353876893846488,0.690462087882705,0.06211680648946061,0.7989629703796846,1.3983135936646063,1.554072857182752,0.23295871445948424,-0.36996889215618123,-0.4349803471134479,-0.5638942876356867,0.7989629703796846,0.9824117244906789,-0.1394094247514785,-0.23880560493110126,0.30206435300525497,-0.1394094247514785,0.3716218440786248,0.5475501784669402,0.02826992735684619,-0.7545819832932289,0.9824117244906789,1.2070828107445577,-0.005472043382106115,0.6545485118299024,-0.03911004514660509,1.0195061138420503,-0.5318025210216746,1.1692816695624557,-0.8174517203305781,0.40657274055962805,0.7265014927733182,1.1692816695624557,-0.20577244529591113,-0.106077830470184,-0.106077830470184,0.5475501784669402,-0.33732182412727213,2.1205507147690597,0.23295871445948424,-0.4349803471134479,1.7926187250454313,0.30206435300525497,0.13012911860860088,-0.36996889215618123,0.6187594963253328
| 2,466
|
Positive regulation of developmental growth
| 6
| 18
| 2.001969
| 0.045288
|
Q7L576,P80723,P43034,P46821,O00763,Q9UPN3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
326,238,145,108,116,463
|
116,1223,750,1307,1267,145,108,755,445,238,2220,1107,646,326,1672,1123,463,1179
|
1.5148945458722094,-0.005472043382106115,0.3716218440786248,-0.0726450035074068,-0.03911004514660509,1.3983135936646063,1.554072857182752,0.3716218440786248,0.690462087882705,1.09411123321543,-1.0656082337385886,0.09606954757438466,0.4768243999762741,0.8719435308811879,-0.33732182412727213,0.09606954757438466,0.690462087882705,0.06211680648946061
| 2,466
|
Aplasia of the fingers
| 8
| 24
| 1.996696
| 0.045858
|
Q07020,P18077,P62899,P61313,P60866,Q13618,P08708,Q9NVI1
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
343,160,109,19,310,285,281,158
|
1294,1830,281,160,595,1606,419,754,1231,310,923,19,1397,1452,756,837,2146,109,1873,343,285,1279,646,158
|
-0.0726450035074068,-0.49962010917283683,0.9824117244906789,1.2831250541224368,0.5121274427616084,-0.3045794640677411,0.7265014927733182,0.3716218440786248,-0.005472043382106115,0.9086318760961686,0.23295871445948424,2.9517648784557937,-0.1394094247514785,-0.17264067204748582,0.3716218440786248,0.30206435300525497,-0.9111253589916372,1.554072857182752,-0.5318025210216746,0.8353876893846488,0.9824117244906789,-0.03911004514660509,0.4768243999762741,1.3213694940336442
| 2,466
|
Abnormality of earlobe
| 11
| 23
| 1.996198
| 0.045912
|
O60701,P53992,P46109,P98175,Q8IWS0,P53701,P28482,Q13620,Q96GM5,Q9BZK7,Q15392
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
277,540,441,446,578,146,437,514,522,586,88
|
955,277,1094,2089,437,441,1017,146,540,1650,446,514,1237,88,1619,578,1026,1077,522,896,651,586,1034
|
0.19857269655533746,0.9824117244906789,0.09606954757438466,-0.8174517203305781,0.690462087882705,0.690462087882705,0.16429650233449708,1.3983135936646063,0.5830937941090167,-0.33732182412727213,0.690462087882705,0.6187594963253328,-0.005472043382106115,1.672588769694534,-0.3045794640677411,0.5475501784669402,0.16429650233449708,0.13012911860860088,0.6187594963253328,0.26745558495361116,0.4768243999762741,0.5475501784669402,0.16429650233449708
| 2,466
|
Predicted membrane proteins
| 122
| 450
| 6.600585
| 0
|
Q99595,Q70HW3,P24390,Q8N511,Q8IXU6,Q6NT16,Q567V2,Q9BQE5,Q9Y282,O43169,Q9NS69,P30519,P08183,Q8NBX0,Q86XL3,O75844,Q8WTV0,O43772,P42892,P53985,Q7L0J3,Q16850,O60725,O43676,Q9HD20,Q8N0U8,O95772,Q9UIQ6,Q15392,Q13505,Q9UBU6,Q9H061,Q93050,P33527,Q8NCH0,Q14108,Q8NCC3,Q9C0H2,Q9H4I3,Q16739,Q92896,Q06136,Q8IV08,Q9H6V9,O00461,Q9NZ45,Q96G23,O60637,Q5BJF2,Q13423,P49257,Q96CP7,Q9Y619,O15173,Q8TB61,Q9Y2R0,P43307,P37268,Q9UDW1,Q10472,Q14739,Q5H8A4,O75964,Q9BTX1,Q9HD45,O15269,O96005,Q9H1E5,Q9NZ01,Q9UDX5,O95197,P67812,Q9Y487,Q99805,P39210,P09669,Q8NC54,Q92804,P04920,O43657,P50851,Q9UBX3,O15258,P35613,O15121,P11717,P11117,Q14574,P62942,Q92544,P16435,Q9BZF1,Q3SXM5,Q15629,Q8NBU5,P35610,Q9Y5M8,O43493,O95470,O75976,Q8IZA0,Q9HBM0,Q8N4V1,Q9P2W9,Q15904,O95864,O76062,Q6NUM9,Q9HC07,O95831,Q8TCT9,Q9Y262,Q9NPL8,Q9NQC3,P49841,P00403,Q99808,Q12893,Q9BT22,Q16513,Q07065,Q9Y3Q3
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
2,3,5,6,13,15,17,20,21,24,29,27,32,33,35,36,38,37,39,40,41,43,44,46,47,49,51,58,61,63,65,70,76,75,85,84,88,89,90,92,94,98,100,103,101,115,114,111,116,117,119,121,125,126,128,129,132,131,136,138,139,142,143,144,146,153,154,158,161,167,168,173,181,180,176,175,183,189,187,186,193,199,208,214,218,221,229,231,238,242,245,264,261,259,262,255,268,266,269,276,285,287,286,288,284,282,289,305,307,298,314,317,330,331,327,324,342,350,354,351,349,368
|
1049,1566,2113,570,101,778,2151,1050,1335,1438,683,1568,751,808,485,977,218,488,978,126,208,153,605,2083,24,1868,1441,266,186,46,1726,383,37,534,1299,1442,2084,952,111,44,1054,1728,1120,371,907,2281,2086,1085,1267,979,1412,36,1641,2056,143,276,289,1794,1477,372,658,837,554,489,168,1300,2239,269,1121,1996,51,298,282,154,1683,324,432,1479,1231,1195,187,981,1642,2157,1963,1301,32,1481,2057,522,175,537,384,229,491,2294,1484,221,811,1612,1154,1687,245,434,1447,1341,1690,415,984,394,5,757,2059,1237,1490,596,27,523,1870,1835,75,611,759,255,214,666,879,131,1534,176,1697,39,132,613,734,1307,119,692,327,818,193,508,1309,1735,638,2392,669,2317,1900,40,993,2283,1245,419,1498,671,2068,788,2318,2399,2128,1064,238,173,579,2008,2070,1417,2455,1803,998,1313,98,849,349,138,1581,1281,1874,350,1741,1131,923,695,1354,1765,117,63,1623,84,1033,1456,1503,541,231,453,139,584,1136,1655,560,1979,698,1283,61,259,2258,1544,619,284,721,351,2259,890,92,1168,43,602,1217,261,456,1507,1390,17,116,142,2319,1847,1980,722,2446,1810,2271,2048,2178,1586,1879,439,15,305,2228,1708,1141,1945,1744,1000,1069,1510,3,700,41,1356,1285,1071,1812,35,858,474,100,1511,1881,1588,603,13,931,285,49,423,892,286,6,2229,893,1882,2141,262,33,183,1286,88,85,2181,1663,1038,1853,128,475,859,1393,314,1854,38,1512,1774,1855,2144,1665,242,2166,2311,678,1175,895,1710,1325,1950,189,94,76,724,2230,1142,2342,897,1257,121,1430,2462,2011,1514,114,624,745,1712,1289,801,442,1431,647,1551,968,2410,1361,1776,1746,2351,969,1177,746,2287,2,443,1115,180,342,2274,1714,20,2313,2015,354,1179,831,144,1594,1717,2467,1718,747,1778,2050,593,264,2249,89,2051,70,863,703,158,1366,2262,1557,1396,1006,1886,1292,1598,90,2232,103,1433,1633,287,307,834,481,47,146,1914,1145,1887,330,331,604,29,627,1750,1368,402,550,1723,1954,161,115,628,482,1916,1821,288,942,1470,65,681,199,136,167,2292,1560,806,1370,58,1563,2365,749,532,317,974,21,518,1788,1402,129,1677,1298,946,367,391,775,368,392,181,519,2150,268,975,125,1889,1918,1437
|
0.07343946733113242,-0.3150370549937861,-0.8202718560579666,0.49139101679695213,1.8961668597006474,0.27676037958362715,-0.8543859267849101,0.07343946733113242,-0.1430695347463049,-0.22797146657486117,0.3739010819588171,-0.3150370549937861,0.3013170110599651,0.25201882658425456,0.6047569844332618,0.1254502957539166,1.1738760097490326,0.6047569844332618,0.1254502957539166,1.6535024833174539,1.2107906833937936,1.4909169970454357,0.44490440798943937,-0.7864806683003362,3.0644817206400434,-0.5585543448403263,-0.22797146657486117,1.0410518943199942,1.2833019254548965,2.644730419435073,-0.4346601796282852,0.7570047251940325,2.857903513986415,0.5372180454514659,-0.11523365842189977,-0.22797146657486117,-0.7864806683003362,0.15115395482942545,1.807535106013106,2.666835954385971,0.07343946733113242,-0.4346601796282852,0.020605480698360126,0.7781699552447922,0.17666003360338126,-1.139599641176551,-0.7864806683003362,0.047126781746465576,-0.08762466761145592,0.1254502957539166,-0.1994350717264357,2.868122282262257,-0.3743308591385381,-0.7530070814189461,1.5733299672243768,1.0020254240102997,0.9625009483378237,-0.4960569056469889,-0.2567482190180186,0.7781699552447922,0.3977415176858454,0.22708991471684983,0.5143859578494419,0.6047569844332618,1.3715614817905903,-0.11523365842189977,-1.0299934512102915,1.0216002256059087,0.020605480698360126,-0.6869921898793442,2.5544363806012425,0.9425484828699386,0.9823261264765617,1.4909169970454357,-0.4043641190777143,0.8819129546814536,0.6709000913867084,-0.2567482190180186,-0.06023936284890438,-0.033074608598505244,1.2833019254548965,0.1254502957539166,-0.3743308591385381,-0.8543859267849101,-0.65444091817572,-0.11523365842189977,2.908601987092757,-0.2567482190180186,-0.7530070814189461,0.5598892765754294,1.3189165219976549,0.5372180454514659,0.7570047251940325,1.1365094929601929,0.6047569844332618,-1.1768795353111265,-0.2567482190180186,1.1738760097490326,0.25201882658425456,-0.34455645734238355,-0.006127331605984542,-0.4043641190777143,1.0795911798832665,0.6709000913867084,-0.22797146657486117,-0.1430695347463049,-0.4043641190777143,0.692646228876154,0.1254502957539166,0.7356968204452725,3.8314985860427604,0.3013170110599651,-0.7530070814189461,-0.06023936284890438,-0.2567482190180186,0.4682311897943023,2.928608323075618,0.5598892765754294,-0.5585543448403263,-0.5271658967301447,2.199400481282764,0.44490440798943937,0.3013170110599651,1.0603817720347808,1.192389231232484,0.3977415176858454,0.20197116058474252,1.6376421273678423,-0.2857688748733796,1.3189165219976549,-0.4043641190777143,2.827005651000117,1.6376421273678423,0.44490440798943937,0.3256911134093675,-0.11523365842189977,1.7468979457042964,0.3739010819588171,0.8819129546814536,0.25201882658425456,1.2653360299982175,0.58240161346863,-0.11523365842189977,-0.4346601796282852,0.42140856532916043,-1.6138737694884546,0.3977415176858454,-1.2525962685132521,-0.590226648688484,2.827005651000117,0.1254502957539166,-1.139599641176551,-0.06023936284890438,0.692646228876154,-0.2567482190180186,0.3977415176858454,-0.7530070814189461,0.27676037958362715,-1.2525962685132521,-1.6562527119273847,-0.8202718560579666,0.07343946733113242,1.117653769245169,1.3365673787376733,0.49139101679695213,-0.6869921898793442,-0.7530070814189461,-0.1994350717264357,-3.32698538543746,-0.4960569056469889,0.1254502957539166,-0.11523365842189977,1.9251128862095315,0.22708991471684983,0.8200789823454424,1.6056618506283145,-0.3150370549937861,-0.08762466761145592,-0.5585543448403263,0.8200789823454424,-0.4346601796282852,0.020605480698360126,0.17666003360338126,0.3739010819588171,-0.1430695347463049,-0.46522306940850683,1.7773752159481948,2.388772456730667,-0.34455645734238355,2.119881427808456,0.09954637705818221,-0.22797146657486117,-0.2567482190180186,0.5372180454514659,1.1365094929601929,0.6490043765907978,1.6056618506283145,0.49139101679695213,0.020605480698360126,-0.3743308591385381,0.5143859578494419,-0.65444091817572,0.3739010819588171,-0.08762466761145592,2.4130652487639477,1.0603817720347808,-1.066163090613305,-0.2857688748733796,0.44490440798943937,0.9823261264765617,0.34988503514948976,0.8200789823454424,-1.066163090613305,0.20197116058474252,2.024171009993822,-0.006127331605984542,2.7427903084146905,0.4682311897943023,-0.033074608598505244,1.0603817720347808,0.6490043765907978,-0.2567482190180186,-0.17113556168396907,3.202482497522664,1.7924944732535362,1.5895402794086952,-1.2525962685132521,-0.5271658967301447,-0.65444091817572,0.34988503514948976,-2.959510953601851,-0.4960569056469889,-1.1026963504909864,-0.7198459356446938,-0.8888282886905626,-0.3150370549937861,-0.5585543448403263,0.6709000913867084,3.3248211178078995,0.9425484828699386,-0.994181179090294,-0.4043641190777143,0.020605480698360126,-0.6221873063453945,-0.4346601796282852,0.1254502957539166,0.07343946733113242,-0.2567482190180186,4.09320199924866,0.3739010819588171,2.827005651000117,-0.1430695347463049,-0.08762466761145592,0.07343946733113242,-0.4960569056469889,2.87830124590930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| 2,468
|
Endoplasmic reticulum
| 88
| 385
| 4.796609
| 0.000002
|
P24390,Q8N511,Q9BQE5,Q9Y282,P30519,Q9UQB8,Q86XL3,O75844,Q7L0J3,Q16850,O60725,Q9HD20,Q8N0U8,O95772,Q15392,P80303,Q9UBU6,O75503,P30536,P10619,Q14108,P27635,Q01105,Q06136,Q8IV08,Q9H6V9,P07099,Q96G23,Q14257,Q5BJF2,P49257,O15173,Q8TB61,P43307,P37268,Q02818,Q10472,Q14739,Q9UMX5,Q5H8A4,Q9BTY2,O15269,Q9NZ01,O95197,O43852,P63241,P67812,Q9Y4P3,P48723,P50851,P62266,O15258,P35613,P39687,O15121,Q15042,P04062,P62942,P16435,Q9BZF1,Q15629,P35610,Q9Y5M8,O43493,O95470,Q15437,P84157,Q8N4V1,Q9P2W9,Q15904,O95864,O00584,O76062,P35606,Q9Y678,Q6NUM9,P52789,Q15436,Q8TCT9,P23396,Q9NQC3,Q9BT22,Q07065,Q9Y3Q3,Q9Y3B3,Q13510,P62820,Q9UNN5
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
5,6,20,21,27,34,35,36,41,43,44,47,49,51,61,64,65,66,73,81,84,83,87,98,100,103,104,114,113,116,119,126,128,132,131,137,138,139,140,142,152,153,161,168,170,171,173,190,188,193,194,208,214,215,218,233,236,238,245,264,259,255,268,266,269,279,278,286,288,284,282,281,289,291,295,305,303,304,314,311,331,354,349,368,367,361,359,381
|
1049,570,412,778,281,1438,750,683,1568,808,1407,977,218,126,208,153,1681,1725,1408,266,1637,170,505,952,685,44,1476,2402,2086,1961,66,1267,1230,1412,36,2056,289,573,2197,1192,1523,489,168,2239,909,659,269,1996,51,1269,282,1730,1683,236,1479,1758,1231,1195,981,1527,781,104,1086,1925,2116,522,1483,384,81,838,1997,1686,2375,1796,1340,1376,245,434,1447,1341,1833,1574,2449,1691,1797,2118,984,1896,311,5,915,1343,758,1646,2059,1198,83,1380,2030,1237,634,1491,1024,2296,2033,27,840,73,1966,374,1835,759,291,255,214,784,1238,131,1534,1697,215,1614,132,1201,1092,916,734,881,493,188,691,1242,119,762,692,818,1969,193,1309,1735,638,669,509,303,1126,843,1537,419,1699,2038,1838,882,671,2068,2318,2004,1206,2304,1701,1499,1738,1385,2399,2128,764,920,194,886,359,578,2130,238,1937,171,173,64,921,790,278,2008,1417,87,1542,1454,137,1418,2435,998,98,1129,349,1619,138,1281,1130,1741,1650,1131,1420,923,1806,361,1623,84,1456,113,1503,541,1767,139,1214,1136,2136,1655,233,2046,1979,926,797,698,61,1808,304,279,259,1846,2258,619,284,890,43,602,1035,1390,116,142,2319,1847,1586,1457,1879,305,2228,1141,1069,1427,1510,700,41,1356,2245,1071,1812,35,858,100,2328,1511,49,2339,286,6,2229,893,1882,2141,1947,1628,1286,1663,1038,1853,1001,128,1983,1393,2340,314,1948,1854,621,1460,1855,1665,2166,2311,895,1950,896,1775,724,2230,1142,897,1257,514,1430,114,624,1463,701,1289,442,647,1551,2410,1040,969,1986,443,1115,2274,20,401,1291,2015,354,1179,152,1594,1717,1718,747,264,2249,863,1597,1632,773,727,1886,1598,2431,1467,103,899,481,47,1145,1887,331,941,627,2387,1723,2112,161,427,482,1916,1821,516,288,748,942,65,681,1822,2292,1560,462,903,1080,517,1563,140,2365,381,1436,34,21,1520,1298,946,367,1473,368,1405,1679,190,268,1889,295,1918,654
|
0.07343946733113242,0.49139101679695213,0.692646228876154,0.27676037958362715,0.9823261264765617,-0.22797146657486117,0.3013170110599651,0.3739010819588171,-0.3150370549937861,0.25201882658425456,-0.1994350717264357,0.1254502957539166,1.1738760097490326,1.6535024833174539,1.2107906833937936,1.4909169970454357,-0.4043641190777143,-0.4346601796282852,-0.1994350717264357,1.0410518943199942,-0.3743308591385381,1.3541153522401639,0.58240161346863,0.15115395482942545,0.3739010819588171,2.666835954385971,-0.2567482190180186,-1.742458928246437,-0.7864806683003362,-0.65444091817572,2.3395309528321633,-0.08762466761145592,-0.06023936284890438,-0.1994350717264357,2.868122282262257,-0.7530070814189461,0.9625009483378237,0.49139101679695213,-0.9236044800386676,-0.033074608598505244,-0.2857688748733796,0.6047569844332618,1.3715614817905903,-1.0299934512102915,0.17666003360338126,0.3977415176858454,1.0216002256059087,-0.6869921898793442,2.5544363806012425,-0.08762466761145592,0.9823261264765617,-0.4346601796282852,-0.4043641190777143,1.117653769245169,-0.2567482190180186,-0.46522306940850683,-0.06023936284890438,-0.033074608598505244,0.1254502957539166,-0.2857688748733796,0.27676037958362715,1.8815833993429565,0.047126781746465576,-0.6221873063453945,-0.8202718560579666,0.5598892765754294,-0.2567482190180186,0.7570047251940325,2.1599235408173723,0.22708991471684983,-0.6869921898793442,-0.4043641190777143,-1.4895231624354457,-0.4960569056469889,-0.1430695347463049,-0.17113556168396907,1.0795911798832665,0.6709000913867084,-0.22797146657486117,-0.1430695347463049,-0.5271658967301447,-0.3150370549937861,-3.078970856737308,-0.4043641190777143,-0.4960569056469889,-0.8202718560579666,0.1254502957539166,-0.590226648688484,0.9224673008330843,3.8314985860427604,0.17666003360338126,-0.1430695347463049,0.3013170110599651,-0.3743308591385381,-0.7530070814189461,-0.033074608598505244,2.119881427808456,-0.17113556168396907,-0.7198459356446938,-0.06023936284890438,0.42140856532916043,-0.2567482190180186,0.09954637705818221,-1.1768795353111265,-0.7198459356446938,2.928608323075618,0.22708991471684983,2.238325990048142,-0.65444091817572,0.7781699552447922,-0.5271658967301447,0.3013170110599651,0.9625009483378237,1.0603817720347808,1.192389231232484,0.27676037958362715,-0.06023936284890438,1.6376421273678423,-0.2857688748733796,-0.4043641190777143,1.192389231232484,-0.34455645734238355,1.6376421273678423,-0.033074608598505244,0.047126781746465576,0.17666003360338126,0.3256911134093675,0.20197116058474252,0.6047569844332618,1.2833019254548965,0.3739010819588171,-0.06023936284890438,1.7468979457042964,0.3013170110599651,0.3739010819588171,0.25201882658425456,-0.65444091817572,1.2653360299982175,-0.11523365842189977,-0.4346601796282852,0.42140856532916043,0.3977415176858454,0.58240161346863,0.9425484828699386,0.020605480698360126,0.22708991471684983,-0.2857688748733796,0.692646228876154,-0.4043641190777143,-0.7198459356446938,-0.5271658967301447,0.20197116058474252,0.3977415176858454,-0.7530070814189461,-1.2525962685132521,-0.6869921898793442,-0.033074608598505244,-1.214542773220608,-0.4043641190777143,-0.2567482190180186,-0.4346601796282852,-0.17113556168396907,-1.6562527119273847,-0.8202718560579666,0.3013170110599651,0.17666003360338126,1.2653360299982175,0.20197116058474252,0.7991941651751763,0.49139101679695213,-0.8202718560579666,1.117653769245169,-0.6221873063453945,1.3541153522401639,1.3365673787376733,2.3642621621233513,0.17666003360338126,0.27676037958362715,1.0020254240102997,-0.6869921898793442,-0.1994350717264357,2.0792599080996506,-0.2857688748733796,-0.22797146657486117,1.6056618506283145,-0.1994350717264357,-2.3553677588654476,0.1254502957539166,1.9251128862095315,0.020605480698360126,0.8200789823454424,-0.34455645734238355,1.6056618506283145,-0.08762466761145592,0.020605480698360126,-0.4346601796282852,-0.3743308591385381,0.020605480698360126,-0.1994350717264357,0.17666003360338126,-0.4960569056469889,0.7991941651751763,-0.34455645734238355,2.119881427808456,-0.22797146657486117,1.807535106013106,-0.2567482190180186,0.5372180454514659,-0.46522306940850683,1.6056618506283145,-0.033074608598505244,0.020605480698360126,-0.8202718560579666,-0.3743308591385381,1.1365094929601929,-0.7198459356446938,-0.65444091817572,0.17666003360338126,0.27676037958362715,0.3739010819588171,2.4130652487639477,-0.4960569056469889,0.9425484828699386,1.0020254240102997,1.0603817720347808,-0.5271658967301447,-1.066163090613305,0.44490440798943937,0.9823261264765617,0.20197116058474252,2.7427903084146905,0.4682311897943023,0.09954637705818221,-0.17113556168396907,1.7924944732535362,1.5895402794086952,-1.2525962685132521,-0.5271658967301447,-0.3150370549937861,-0.22797146657486117,-0.5585543448403263,0.9425484828699386,-0.994181179090294,0.020605480698360126,0.07343946733113242,-0.1994350717264357,-0.2567482190180186,0.3739010819588171,2.827005651000117,-0.1430695347463049,-1.0299934512102915,0.07343946733113242,-0.4960569056469889,2.8783012459093062,0.22708991471684983,1.9106764725104468,-1.2910471139088535,-0.2567482190180186,2.5886536324101614,-1.3299025873109733,0.9823261264765617,3.681490447648572,-0.994181179090294,0.20197116058474252,-0.5585543448403263,-0.8202718560579666,-0.6221873063453945,-0.34455645734238355,-0.08762466761145592,-0.3743308591385381,0.09954637705818221,-0.5271658967301447,0.1254502957539166,1.6535024833174539,-0.65444091817572,-0.17113556168396907,-1.3299025873109733,0.9224673008330843,-0.6221873063453945,-0.5271658967301447,0.44490440798943937,-0.22797146657486117,-0.5271658967301447,-0.3743308591385381,-0.8543859267849101,-1.214542773220608,0.20197116058474252,-0.6221873063453945,0.20197116058474252,-0.46522306940850683,0.34988503514948976,-0.994181179090294,0.020605480698360126,0.20197116058474252,-0.06023936284890438,0.58240161346863,-0.1994350717264357,1.807535106013106,0.44490440798943937,-0.22797146657486117,0.3739010819588171,-0.08762466761145592,0.6709000913867084,0.42140856532916043,-0.2857688748733796,-1.7863055278776567,0.09954637705818221,0.15115395482942545,-0.65444091817572,0.6709000913867084,0.047126781746465576,-1.1026963504909864,3.139012561494263,0.7356968204452725,-0.08762466761145592,-0.6869921898793442,0.8200789823454424,-0.006127331605984542,1.5075840575864408,-0.3150370549937861,-0.4043641190777143,-0.4043641190777143,0.3256911134093675,1.0603817720347808,-1.0299934512102915,0.22708991471684983,-0.3150370549937861,-0.34455645734238355,0.3013170110599651,0.34988503514948976,-0.5585543448403263,-0.3150370549937861,-2.254584687983832,-0.22797146657486117,1.8961668597006474,0.20197116058474252,0.6269572845849924,2.6224404188956902,0.020605480698360126,-0.5585543448403263,0.8819129546814536,0.17666003360338126,0.44490440798943937,-1.5719651640648913,-0.4043641190777143,-0.7864806683003362,1.457299817470005,0.692646228876154,0.6269572845849924,-0.590226648688484,-0.4960569056469889,0.58240161346863,0.9823261264765617,0.3256911134093675,0.17666003360338126,2.351924388044598,0.3977415176858454,-0.4960569056469889,-1.139599641176551,-0.2857688748733796,0.6490043765907978,0.20197116058474252,0.07343946733113242,0.58240161346863,-0.2857688748733796,1.6056618506283145,-1.4088574939002534,0.7781699552447922,-0.1994350717264357,2.8985408330958538,3.129814463490708,-0.2567482190180186,-0.08762466761145592,0.17666003360338126,0.7991941651751763,-0.22797146657486117,0.7991941651751763,-0.17113556168396907,-0.3743308591385381,1.2833019254548965,1.0410518943199942,-0.5585543448403263,0.9625009483378237,-0.590226648688484,0.42140856532916043
| 2,468
|
Peptidase activity
| 39
| 90
| 4.66077
| 0.000003
|
Q96BN8,Q10713,P42785,Q96FW1,P52888,O14773,Q5JRX3,P55786,O75976,P60900,Q86UV5,P50579,P09960,Q9NZ08,O75844,Q99436,P42892,P67812,Q4J6C6,Q8IYS1,Q8TCT9,P49721,P28074,Q9UIQ6,P22695,P02786,Q9HB40,Q9H3G5,P20618,P07858,P10619,Q9UPU5,O43847,P28070,P49720,Q9BT78,Q9BYT8,P28072,Q92905
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
388,257,8,399,12,141,272,23,276,408,410,28,283,427,36,164,39,173,174,440,314,56,54,58,59,432,68,74,202,80,81,212,345,225,230,105,250,373,263
|
682,2221,141,572,345,1606,36,276,2154,432,1644,80,283,81,2416,1235,873,202,59,1305,225,373,54,2334,2031,2033,879,1696,2035,539,8,39,1161,1899,230,56,28,557,12,1616,1061,23,408,173,257,1455,794,1167,1136,455,174,2102,272,1706,1547,930,1356,410,440,314,1665,895,827,896,263,828,513,1142,388,399,1746,164,1630,1986,1910,105,250,1396,74,1007,1748,68,1862,940,2387,427,58,212,2150,1475
|
0.3739010819588171,-0.994181179090294,1.5895402794086952,0.49139101679695213,0.8200789823454424,-0.34455645734238355,2.868122282262257,1.0020254240102997,-0.8543859267849101,0.6709000913867084,-0.3743308591385381,2.1599235408173723,0.9823261264765617,2.1599235408173723,-1.9209411773807756,-0.06023936284890438,0.20197116058474252,1.2290815354843998,2.461011602486414,-0.11523365842189977,1.1552498319919475,0.7781699552447922,2.4964247239663777,-1.3299025873109733,-0.7198459356446938,-0.7198459356446938,0.20197116058474252,-0.4043641190777143,-0.7198459356446938,0.5372180454514659,3.5056872507526013,2.827005651000117,-0.006127331605984542,-0.590226648688484,1.1365094929601929,2.4964247239663777,2.928608323075618,0.5143859578494419,3.4332901983397086,-0.34455645734238355,0.07343946733113242,3.0739178449056257,0.7142445586094798,1.3365673787376733,1.0603817720347808,-0.22797146657486117,0.27676037958362715,-0.006127331605984542,0.020605480698360126,0.6490043765907978,1.3365673787376733,-0.7864806683003362,1.0216002256059087,-0.4043641190777143,-0.2857688748733796,0.17666003360338126,-0.1430695347463049,0.7142445586094798,0.6709000913867084,0.9224673008330843,-0.3743308591385381,0.20197116058474252,0.25201882658425456,0.20197116058474252,1.0603817720347808,0.25201882658425456,0.58240161346863,0.020605480698360126,0.7570047251940325,0.7356968204452725,-0.4346601796282852,1.4232989777185565,-0.34455645734238355,-0.65444091817572,-0.590226648688484,1.8669254347810549,1.0795911798832665,-0.17113556168396907,2.2254112620780373,0.1254502957539166,-0.4346601796282852,2.3270814179529142,-0.5271658967301447,0.17666003360338126,-1.5719651640648913,0.692646228876154,2.4728673792906726,1.2107906833937936,-0.8202718560579666,-0.22797146657486117
| 2,468
|
Lysosome
| 21
| 42
| 4.402421
| 0.000011
|
Q9UMR5,O14773,P16278,Q15904,P07602,Q9Y487,P04066,O75503,Q9Y2T2,P15586,Q93050,P07858,P10619,P06865,Q14108,P06280,Q8NCC3,P11717,P11117,P04062,P50897
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
133,141,18,284,31,181,310,66,332,325,76,80,81,209,84,339,88,221,229,236,112
|
835,729,1119,141,977,1637,1793,66,236,310,339,209,31,536,80,1831,1234,81,229,1484,221,325,18,609,112,693,1702,847,1314,361,84,284,88,1111,76,1004,628,1117,1956,133,332,181
|
0.22708991471684983,0.3256911134093675,0.020605480698360126,1.5895402794086952,0.1254502957539166,-0.3743308591385381,-0.4960569056469889,2.3395309528321633,1.117653769245169,0.9224673008330843,0.8408260074769911,1.2107906833937936,2.908601987092757,0.5372180454514659,2.1599235408173723,-0.5271658967301447,-0.06023936284890438,2.1599235408173723,1.1365094929601929,-0.2567482190180186,1.1738760097490326,0.8819129546814536,3.1754755052007098,0.44490440798943937,1.807535106013106,0.3739010819588171,-0.4043641190777143,0.22708991471684983,-0.11523365842189977,0.7991941651751763,2.119881427808456,0.9823261264765617,2.065588110324613,0.047126781746465576,2.199400481282764,0.1254502957539166,0.44490440798943937,0.047126781746465576,-0.6221873063453945,1.6376421273678423,0.8819129546814536,1.3189165219976549
| 2,468
|
Endopeptidase activity
| 24
| 50
| 4.21323
| 0.000025
|
Q10713,P52888,O14773,Q5JRX3,P60900,Q86UV5,Q99436,O75844,P42892,P67812,Q4J6C6,Q8TCT9,P49721,P28074,P22695,P20618,P07858,Q9UPU5,O43847,P28070,P49720,Q9BYT8,P28072,Q92905
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
257,12,141,272,408,410,164,36,39,173,174,314,56,54,59,202,80,212,345,225,230,250,373,263
|
141,345,1606,36,1644,80,1235,873,202,59,1305,225,373,54,2031,2033,1696,2035,539,39,1161,1899,230,56,12,1061,408,173,257,794,1167,455,174,272,1706,410,314,1665,895,263,828,513,1746,164,1910,250,1396,427,212,2150
|
1.5895402794086952,0.8200789823454424,-0.34455645734238355,2.868122282262257,-0.3743308591385381,2.1599235408173723,-0.06023936284890438,0.20197116058474252,1.2290815354843998,2.461011602486414,-0.11523365842189977,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.7198459356446938,-0.7198459356446938,-0.4043641190777143,-0.7198459356446938,0.5372180454514659,2.827005651000117,-0.006127331605984542,-0.590226648688484,1.1365094929601929,2.4964247239663777,3.4332901983397086,0.07343946733113242,0.7142445586094798,1.3365673787376733,1.0603817720347808,0.27676037958362715,-0.006127331605984542,0.6490043765907978,1.3365673787376733,1.0216002256059087,-0.4043641190777143,0.7142445586094798,0.9224673008330843,-0.3743308591385381,0.20197116058474252,1.0603817720347808,0.25201882658425456,0.58240161346863,-0.4346601796282852,1.4232989777185565,-0.590226648688484,1.0795911798832665,-0.17113556168396907,0.692646228876154,1.2107906833937936,-0.8202718560579666
| 2,468
|
Vacuolar lumen
| 20
| 53
| 4.051274
| 0.000051
|
Q9UMR5,O14773,P16278,Q9BTY2,P07602,O00584,P07437,P68371,P04066,P15586,P07858,P10619,P06865,Q14108,P06280,Q8IV08,P11117,Q99536,P04062,P50897
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
133,141,18,152,31,281,299,312,310,325,80,81,209,84,339,100,229,235,236,112
|
281,729,141,1637,1683,236,310,339,209,1829,299,31,536,80,732,1234,81,229,1445,1302,325,18,609,634,1694,1534,1579,112,819,1027,1244,693,1699,735,312,497,1248,1806,361,84,1213,100,1628,2204,827,1430,1177,235,152,1364,628,133,531
|
0.9823261264765617,0.3256911134093675,1.5895402794086952,-0.3743308591385381,-0.4043641190777143,1.117653769245169,0.9224673008330843,0.8408260074769911,1.2107906833937936,-0.5271658967301447,0.9425484828699386,2.908601987092757,0.5372180454514659,2.1599235408173723,0.3256911134093675,-0.06023936284890438,2.1599235408173723,1.1365094929601929,-0.22797146657486117,-0.11523365842189977,0.8819129546814536,3.1754755052007098,0.44490440798943937,0.42140856532916043,-0.4043641190777143,-0.2857688748733796,-0.3150370549937861,1.807535106013106,0.25201882658425456,0.09954637705818221,-0.06023936284890438,0.3739010819588171,-0.4043641190777143,0.3256911134093675,0.9224673008330843,0.6047569844332618,-0.06023936284890438,-0.4960569056469889,0.7991941651751763,2.119881427808456,-0.033074608598505244,1.9106764725104468,-0.34455645734238355,-0.9236044800386676,0.25201882658425456,-0.1994350717264357,-0.006127331605984542,1.1365094929601929,1.5075840575864408,-0.1430695347463049,0.44490440798943937,1.6376421273678423,0.5598892765754294
| 2,468
|
Protease
| 28
| 63
| 4.039559
| 0.000054
|
Q96BN8,P42785,Q96FW1,P52888,O14773,Q5JRX3,P55786,O75976,Q86UV5,P50579,P09960,Q99436,O75844,P42892,P67812,Q4J6C6,Q8TCT9,P28074,Q9UIQ6,Q9HB40,Q9H3G5,P07858,P10619,Q9UPU5,O43847,Q9BYT8,P28072,Q92905
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
388,8,399,12,141,272,23,276,410,28,283,164,36,39,173,174,314,54,58,68,74,80,81,212,345,250,373,263
|
682,2221,141,345,1606,36,276,1644,80,283,81,2416,873,373,54,2334,2031,1696,2035,539,8,39,1161,1899,28,12,1616,1061,23,173,794,1167,1136,455,174,272,1706,1356,410,314,895,263,828,513,388,399,1746,164,1986,250,1396,74,1007,1748,68,1862,940,2387,427,58,212,2150,1475
|
0.3739010819588171,-0.994181179090294,1.5895402794086952,0.8200789823454424,-0.34455645734238355,2.868122282262257,1.0020254240102997,-0.3743308591385381,2.1599235408173723,0.9823261264765617,2.1599235408173723,-1.9209411773807756,0.20197116058474252,0.7781699552447922,2.4964247239663777,-1.3299025873109733,-0.7198459356446938,-0.4043641190777143,-0.7198459356446938,0.5372180454514659,3.5056872507526013,2.827005651000117,-0.006127331605984542,-0.590226648688484,2.928608323075618,3.4332901983397086,-0.34455645734238355,0.07343946733113242,3.0739178449056257,1.3365673787376733,0.27676037958362715,-0.006127331605984542,0.020605480698360126,0.6490043765907978,1.3365673787376733,1.0216002256059087,-0.4043641190777143,-0.1430695347463049,0.7142445586094798,0.9224673008330843,0.20197116058474252,1.0603817720347808,0.25201882658425456,0.58240161346863,0.7570047251940325,0.7356968204452725,-0.4346601796282852,1.4232989777185565,-0.65444091817572,1.0795911798832665,-0.17113556168396907,2.2254112620780373,0.1254502957539166,-0.4346601796282852,2.3270814179529142,-0.5271658967301447,0.17666003360338126,-1.5719651640648913,0.692646228876154,2.4728673792906726,1.2107906833937936,-0.8202718560579666,-0.22797146657486117
| 2,468
|
Anion transport
| 18
| 64
| 4.017249
| 0.000059
|
Q8TB61,P08183,P21796,P45880,P53985,Q7L0J3,Q9UHG3,Q9UBX3,P30536,P33527,Q9H2D1,Q15042,Q9Y277,Q9Y619,P54105,Q9C0H2,P04920,P07602
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,32,4,7,40,41,10,199,73,75,14,233,275,125,151,89,187,31
|
1567,1637,534,505,1054,1411,2056,1121,1757,187,2157,1963,31,32,1481,537,491,811,1612,277,415,4,1490,73,75,7,2392,2066,40,151,1245,2070,1803,453,1655,233,1544,769,1507,439,2103,1141,41,128,342,1715,1778,89,1365,14,1366,1433,1633,834,1042,628,199,10,1080,1297,275,518,1404,125
|
-0.3150370549937861,-0.3743308591385381,0.5372180454514659,0.58240161346863,0.07343946733113242,-0.1994350717264357,-0.7530070814189461,0.020605480698360126,-0.46522306940850683,1.2833019254548965,-0.8543859267849101,-0.65444091817572,2.908601987092757,2.908601987092757,-0.2567482190180186,0.5372180454514659,0.6047569844332618,0.25201882658425456,-0.34455645734238355,1.0020254240102997,0.692646228876154,3.838410894509741,-0.2567482190180186,2.238325990048142,2.199400481282764,3.6667004853346468,-1.6138737694884546,-0.7530070814189461,2.827005651000117,1.5075840575864408,-0.06023936284890438,-0.7530070814189461,-0.4960569056469889,0.6490043765907978,-0.3743308591385381,1.1365094929601929,-0.2857688748733796,0.3013170110599651,-0.2567482190180186,0.6709000913867084,-0.7864806683003362,0.020605480698360126,2.827005651000117,1.6535024833174539,0.8408260074769911,-0.4043641190777143,-0.46522306940850683,2.0518497400362734,-0.1430695347463049,3.3671029220870046,-0.1430695347463049,-0.1994350717264357,-0.34455645734238355,0.25201882658425456,0.09954637705818221,0.44490440798943937,1.2472629393969026,3.489782484645634,0.07343946733113242,-0.08762466761145592,1.0216002256059087,0.58240161346863,-0.17113556168396907,1.6692773995529553
| 2,468
|
Membrane lipid metabolic process
| 19
| 33
| 3.74798
| 0.000178
|
O95470,Q5H8A4,P16278,O15269,Q9NZ01,P07602,Q8NBX0,Q99805,P04066,P30153,P06865,P06280,Q8NCC3,O15121,Q16739,Q06136,P04062,Q96G23,P50897
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
269,142,18,153,161,31,33,180,310,326,209,339,88,218,92,98,236,114,112
|
218,153,269,236,310,339,209,31,536,18,609,1797,326,112,98,361,92,1105,142,33,88,895,2230,114,2410,1115,180,1598,1723,161,628,482,1916
|
1.1738760097490326,1.4909169970454357,1.0216002256059087,1.117653769245169,0.9224673008330843,0.8408260074769911,1.2107906833937936,2.908601987092757,0.5372180454514659,3.1754755052007098,0.44490440798943937,-0.4960569056469889,0.8819129546814536,1.807535106013106,1.9251128862095315,0.7991941651751763,2.024171009993822,0.047126781746465576,1.5895402794086952,2.908601987092757,2.065588110324613,0.20197116058474252,-0.994181179090294,1.807535106013106,-1.7863055278776567,0.047126781746465576,1.3189165219976549,-0.3150370549937861,-0.4043641190777143,1.457299817470005,0.44490440798943937,0.6269572845849924,-0.590226648688484
| 2,468
|
Lysosomal lumen
| 16
| 30
| 3.736968
| 0.000186
|
O00584,Q9UMR5,Q8IV08,P11117,P15586,P04062,O14773,P07858,P10619,P16278,P06865,Q14108,P06280,P50897,P04066,P07602
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
281,133,100,229,325,236,141,80,81,18,209,84,339,112,310,31
|
281,729,141,1637,236,310,339,209,31,536,80,732,1234,81,229,1445,325,18,609,1534,112,693,361,84,100,1628,2204,1364,628,133
|
0.9823261264765617,0.3256911134093675,1.5895402794086952,-0.3743308591385381,1.117653769245169,0.9224673008330843,0.8408260074769911,1.2107906833937936,2.908601987092757,0.5372180454514659,2.1599235408173723,0.3256911134093675,-0.06023936284890438,2.1599235408173723,1.1365094929601929,-0.22797146657486117,0.8819129546814536,3.1754755052007098,0.44490440798943937,-0.2857688748733796,1.807535106013106,0.3739010819588171,0.7991941651751763,2.119881427808456,1.9106764725104468,-0.34455645734238355,-0.9236044800386676,-0.1430695347463049,0.44490440798943937,1.6376421273678423
| 2,468
|
Sphingolipid metabolic process
| 16
| 25
| 3.690543
| 0.000224
|
Q06136,P30153,P04062,O95470,Q16739,Q99805,P06865,P16278,Q96G23,P50897,P06280,Q8NCC3,O15269,O15121,P07602,Q9NZ01
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
98,326,236,269,92,180,209,18,114,112,339,88,153,218,31,161
|
218,153,269,236,339,209,31,536,18,609,1797,326,112,98,361,92,1105,88,114,180,1723,161,628,482,1916
|
1.1738760097490326,1.4909169970454357,1.0216002256059087,1.117653769245169,0.8408260074769911,1.2107906833937936,2.908601987092757,0.5372180454514659,3.1754755052007098,0.44490440798943937,-0.4960569056469889,0.8819129546814536,1.807535106013106,1.9251128862095315,0.7991941651751763,2.024171009993822,0.047126781746465576,2.065588110324613,1.807535106013106,1.3189165219976549,-0.4043641190777143,1.457299817470005,0.44490440798943937,0.6269572845849924,-0.590226648688484
| 2,468
|
Transport
| 108
| 397
| 3.681696
| 0.000232
|
A6NIH7,Q99595,Q70HW3,P21796,P24390,O43633,P45880,O43615,P52292,Q8IXU6,Q9H2D1,Q6NT16,Q9BQE5,Q9Y282,O43169,P23786,Q9NS69,P08183,O43772,P53985,Q7L0J3,O43676,Q9HD20,P22695,Q13505,Q93050,P33527,Q9C0H2,O00461,P49257,O96000,P46379,Q9Y619,Q8TB61,Q9UDW1,O75964,Q9BTX1,Q6DKK2,Q96PU8,Q9H1E5,O95197,P63241,Q9H269,Q9Y487,Q8NFH4,P04920,O75431,Q8N4H5,Q9UBX3,Q8TD16,Q8IYI6,Q9BPX6,P11717,Q9BZF1,Q15629,Q9H270,Q9Y277,Q15437,Q8N4V1,Q9P2W9,Q15904,O95864,P35606,Q8N668,Q92973,Q9Y678,Q9Y6M9,Q15436,O15397,O43707,Q9Y2T2,P00403,O14949,Q99808,Q12893,Q9Y3Q3,Q9Y3B3,Q99816,P62820,A0AVF1,O75306,Q8TEX9,P23634,Q8N1F7,Q9UNH7,Q99720,Q6N075,P16615,O75436,Q9H267,Q3ZCQ8,Q14728,Q92945,Q9HCU5,Q92538,Q86Y82,Q08379,O60749,Q14203,Q99747,Q9UPT5,O14925,O14964,O15126,O95169,P11166,Q9UL25,Q9Y289
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
1,2,3,4,5,504,7,503,509,13,14,15,20,21,24,26,29,32,37,40,41,46,47,59,63,76,75,89,101,119,122,123,125,128,136,143,144,148,156,158,168,171,172,181,179,187,191,198,199,206,211,217,221,264,259,274,275,279,286,288,284,282,291,292,293,295,309,304,296,297,332,324,323,342,350,368,367,365,359,356,371,387,394,423,428,443,439,434,431,459,456,453,477,481,476,474,471,464,498,501,502,485,487,488,489,491,517,518
|
356,1,1791,2113,2023,835,1567,520,1015,101,2151,1825,655,750,1119,683,751,485,323,487,836,1407,977,488,978,296,1681,24,1725,1441,503,504,46,1637,297,1793,1726,37,534,1638,1053,753,464,1476,2195,1054,1728,2085,1120,2323,371,1229,907,2086,191,431,1922,1374,1411,2225,143,2197,1682,1523,554,489,2403,168,1300,1268,1995,1193,1121,2156,282,122,1019,324,2373,187,981,1642,2157,1480,32,1481,2057,1893,537,491,2294,221,811,1612,574,2117,2381,434,1528,1689,1690,1530,662,1574,914,2171,4,957,1797,2118,2356,1304,59,394,26,5,757,2211,1490,2390,1897,663,75,291,1695,666,1871,2091,1346,612,2297,524,1931,760,1578,556,7,123,2123,2427,881,691,119,637,692,2347,1383,992,1836,1934,960,1735,2392,669,509,918,1616,2066,1126,843,1278,40,1537,2283,1971,1245,670,1699,2298,1246,1451,2068,2318,1737,2159,2304,1701,1702,2399,764,359,961,1740,672,737,171,1841,1801,739,2008,2070,1100,1803,998,2042,1906,471,850,1618,1314,1102,1874,350,1741,1131,923,1354,1622,63,793,1875,1742,498,1213,453,999,1214,2074,698,1283,304,279,259,1544,284,769,721,2348,2370,1168,1423,456,1507,1847,1942,1508,2178,148,439,15,2103,1141,1945,3,1459,41,562,1625,1848,2458,474,13,211,423,198,286,893,292,1110,2142,2181,2285,179,1773,2310,128,2340,206,1854,387,967,621,1460,476,1111,1175,1950,477,293,76,724,1002,2299,1550,1857,2011,1327,1514,1463,1745,1221,156,1713,830,969,746,2,443,501,342,365,217,20,1715,934,2015,144,1717,1718,747,1747,2016,1778,2300,1004,1553,264,2301,680,89,1365,863,1597,158,459,172,274,14,1366,1557,1886,1182,970,1397,1433,1633,650,834,481,47,1042,1145,2251,941,1722,29,1863,1147,1784,1369,628,1821,288,1600,2208,199,136,2292,1560,1117,1400,1370,1786,1297,1990,1956,1753,517,1563,1472,651,1264,428,2365,502,1917,532,275,21,518,332,2190,946,367,368,2293,181,1404,1405,904,1790,125,295,1437,1082,595,309
|
0.7991941651751763,4.1239287394808555,-0.4960569056469889,-0.8202718560579666,-0.7198459356446938,0.22708991471684983,-0.3150370549937861,0.5598892765754294,0.09954637705818221,1.8961668597006474,-0.8543859267849101,-0.5271658967301447,0.3977415176858454,0.3013170110599651,0.020605480698360126,0.3739010819588171,0.3013170110599651,0.6047569844332618,0.8819129546814536,0.6047569844332618,0.22708991471684983,-0.1994350717264357,0.1254502957539166,0.6047569844332618,0.1254502957539166,0.9425484828699386,-0.4043641190777143,3.0644817206400434,-0.4346601796282852,-0.22797146657486117,0.58240161346863,0.58240161346863,2.644730419435073,-0.3743308591385381,0.9425484828699386,-0.4960569056469889,-0.4346601796282852,2.857903513986415,0.5372180454514659,-0.3743308591385381,0.07343946733113242,0.3013170110599651,0.6269572845849924,-0.2567482190180186,-0.9236044800386676,0.07343946733113242,-0.4346601796282852,-0.7864806683003362,0.020605480698360126,-1.2910471139088535,0.7781699552447922,-0.06023936284890438,0.17666003360338126,-0.7864806683003362,1.2653360299982175,0.6709000913867084,-0.6221873063453945,-0.17113556168396907,-0.1994350717264357,-0.994181179090294,1.5733299672243768,-0.9236044800386676,-0.4043641190777143,-0.2857688748733796,0.5143859578494419,0.6047569844332618,-1.742458928246437,1.3715614817905903,-0.11523365842189977,-0.08762466761145592,-0.6869921898793442,-0.033074608598505244,0.020605480698360126,-0.8543859267849101,0.9823261264765617,1.6849676739945763,0.09954637705818221,0.8819129546814536,-1.4895231624354457,1.2833019254548965,0.1254502957539166,-0.3743308591385381,-0.8543859267849101,-0.2567482190180186,2.908601987092757,-0.2567482190180186,-0.7530070814189461,-0.590226648688484,0.5372180454514659,0.6047569844332618,-1.1768795353111265,1.1738760097490326,0.25201882658425456,-0.34455645734238355,0.49139101679695213,-0.8202718560579666,-1.530517884167907,0.6709000913867084,-0.2857688748733796,-0.4043641190777143,-0.4043641190777143,-0.2857688748733796,0.3977415176858454,-0.3150370549937861,0.17666003360338126,-0.8888282886905626,3.838410894509741,0.15115395482942545,-0.4960569056469889,-0.8202718560579666,-1.4088574939002534,-0.11523365842189977,2.461011602486414,0.7356968204452725,2.9583317443973955,3.8314985860427604,0.3013170110599651,-0.958720173237647,-0.2567482190180186,-1.6138737694884546,-0.590226648688484,0.3977415176858454,2.199400481282764,0.9625009483378237,-0.4043641190777143,0.3977415176858454,-0.5585543448403263,-0.7864806683003362,-0.1430695347463049,0.44490440798943937,-1.1768795353111265,0.5598892765754294,-0.6221873063453945,0.3013170110599651,-0.3150370549937861,0.5143859578494419,3.6667004853346468,1.6692773995529553,-0.8202718560579666,-2.156313870988057,0.20197116058474252,0.3739010819588171,1.7468979457042964,0.42140856532916043,0.3739010819588171,-1.3691701581343436,-0.17113556168396907,0.1254502957539166,-0.5271658967301447,-0.6221873063453945,0.15115395482942545,-0.4346601796282852,-1.6138737694884546,0.3977415176858454,0.58240161346863,0.17666003360338126,-0.34455645734238355,-0.7530070814189461,0.020605480698360126,0.22708991471684983,-0.08762466761145592,2.827005651000117,-0.2857688748733796,-1.139599641176551,-0.65444091817572,-0.06023936284890438,0.3977415176858454,-0.4043641190777143,-1.1768795353111265,-0.06023936284890438,-0.22797146657486117,-0.7530070814189461,-1.2525962685132521,-0.4346601796282852,-0.8543859267849101,-1.214542773220608,-0.4043641190777143,-0.4043641190777143,-1.6562527119273847,0.3013170110599651,0.7991941651751763,0.15115395482942545,-0.4346601796282852,0.3977415176858454,0.3256911134093675,1.3541153522401639,-0.5271658967301447,-0.4960569056469889,0.3256911134093675,-0.6869921898793442,-0.7530070814189461,0.047126781746465576,-0.4960569056469889,0.1254502957539166,-0.7198459356446938,-0.590226648688484,0.6269572845849924,0.22708991471684983,-0.34455645734238355,-0.11523365842189977,0.047126781746465576,-0.5585543448403263,0.8200789823454424,-0.4346601796282852,0.020605480698360126,0.17666003360338126,-0.1430695347463049,-0.34455645734238355,2.388772456730667,0.27676037958362715,-0.5585543448403263,-0.4346601796282852,0.6047569844332618,-0.033074608598505244,0.6490043765907978,0.1254502957539166,-0.033074608598505244,-0.7530070814189461,0.3739010819588171,-0.08762466761145592,0.9425484828699386,1.0020254240102997,1.0603817720347808,-0.2857688748733796,0.9823261264765617,0.3013170110599651,0.34988503514948976,-1.3691701581343436,-1.4489724671135231,-0.006127331605984542,-0.1994350717264357,0.6490043765907978,-0.2567482190180186,-0.5271658967301447,-0.6221873063453945,-0.2567482190180186,-0.8888282886905626,1.524157989067202,0.6709000913867084,3.3248211178078995,-0.7864806683003362,0.020605480698360126,-0.6221873063453945,4.09320199924866,-0.22797146657486117,2.827005651000117,0.5143859578494419,-0.34455645734238355,-0.5271658967301447,-3.455578806441672,0.6269572845849924,3.383816314422708,1.2107906833937936,0.692646228876154,1.2472629393969026,0.9823261264765617,0.20197116058474252,0.9625009483378237,0.047126781746465576,-0.8202718560579666,-0.8888282886905626,-1.139599641176551,1.3189165219976549,-0.46522306940850683,-1.214542773220608,1.6535024833174539,-1.3299025873109733,1.2290815354843998,-0.5271658967301447,0.7570047251940325,0.15115395482942545,0.44490440798943937,-0.22797146657486117,0.6269572845849924,0.047126781746465576,-0.006127331605984542,-0.6221873063453945,0.6269572845849924,0.9625009483378237,2.199400481282764,0.34988503514948976,0.1254502957539166,-1.1768795353111265,-0.2857688748733796,-0.5271658967301447,-0.6869921898793442,-0.11523365842189977,-0.2567482190180186,-0.22797146657486117,-0.4346601796282852,-0.033074608598505244,1.4909169970454357,-0.4043641190777143,0.25201882658425456,0.15115395482942545,0.3256911134093675,4.0993803881071775,0.6709000913867084,0.6047569844332618,0.8408260074769911,0.7991941651751763,1.192389231232484,3.139012561494263,-0.4043641190777143,0.17666003360338126,-0.6869921898793442,1.5570300603921419,-0.4043641190777143,-0.4043641190777143,0.3256911134093675,-0.4346601796282852,-0.6869921898793442,-0.46522306940850683,-1.1768795353111265,0.1254502957539166,-0.2857688748733796,1.0603817720347808,-1.1768795353111265,0.3977415176858454,2.0518497400362734,-0.1430695347463049,0.22708991471684983,-0.3150370549937861,1.4741558928304515,0.6490043765907978,1.3541153522401639,1.0216002256059087,3.3671029220870046,-0.1430695347463049,-0.2857688748733796,-0.5585543448403263,-0.006127331605984542,0.15115395482942545,-0.17113556168396907,-0.1994350717264357,-0.34455645734238355,0.42140856532916043,0.25201882658425456,0.6269572845849924,2.6224404188956902,0.09954637705818221,0.020605480698360126,-1.0299934512102915,0.17666003360338126,-0.4043641190777143,2.928608323075618,-0.5271658967301447,0.020605480698360126,-0.46522306940850683,-0.1430695347463049,0.44490440798943937,-0.4960569056469889,0.9823261264765617,-0.3150370549937861,-0.9236044800386676,1.2472629393969026,1.6216955230183503,-1.139599641176551,-0.2857688748733796,0.047126781746465576,-0.17113556168396907,-0.1430695347463049,-0.46522306940850683,-0.08762466761145592,-0.65444091817572,-0.6221873063453945,-0.4346601796282852,0.58240161346863,-0.2857688748733796,-0.22797146657486117,0.42140856532916043,-0.06023936284890438,0.692646228876154,-1.4088574939002534,0.6047569844332618,-0.590226648688484,0.5598892765754294,1.0216002256059087,3.129814463490708,0.58240161346863,0.8819129546814536,-0.8888282886905626,0.17666003360338126,0.7991941651751763,0.7991941651751763,-1.139599641176551,1.3189165219976549,-0.17113556168396907,-0.17113556168396907,0.20197116058474252,-0.46522306940850683,1.6692773995529553,0.9625009483378237,-0.1994350717264357,0.07343946733113242,0.49139101679695213,0.9425484828699386
| 2,468
|
SLC superfamily of solute carriers
| 10
| 41
| 3.592138
| 0.000328
|
Q8TB61,Q70HW3,O43772,P53985,Q7L0J3,Q8IXU6,Q9H2D1,Q6NT16,Q9Y619,P04920
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
128,3,37,40,41,13,14,15,125,187
|
37,534,1411,1300,1121,187,2157,1481,491,811,1612,2066,40,1245,2070,1803,1544,439,15,2103,1141,3,41,13,128,342,1715,1778,863,14,1366,1433,1633,307,834,628,199,1297,518,125,1437
|
2.857903513986415,0.5372180454514659,-0.1994350717264357,-0.11523365842189977,0.020605480698360126,1.2833019254548965,-0.8543859267849101,-0.2567482190180186,0.6047569844332618,0.25201882658425456,-0.34455645734238355,-0.7530070814189461,2.827005651000117,-0.06023936284890438,-0.7530070814189461,-0.4960569056469889,-0.2857688748733796,0.6709000913867084,3.3248211178078995,-0.7864806683003362,0.020605480698360126,4.09320199924866,2.827005651000117,3.383816314422708,1.6535024833174539,0.8408260074769911,-0.4043641190777143,-0.46522306940850683,0.22708991471684983,3.3671029220870046,-0.1430695347463049,-0.1994350717264357,-0.34455645734238355,0.9425484828699386,0.25201882658425456,0.44490440798943937,1.2472629393969026,-0.08762466761145592,0.58240161346863,1.6692773995529553,-0.1994350717264357
| 2,468
|
Golgi membrane
| 39
| 100
| 3.520229
| 0.000431
|
Q8TB61,Q10713,P24390,P10321,P52292,Q10472,Q9Y282,Q8IZA0,Q8N4V1,Q9P2W9,P35606,Q9Y678,O95197,Q9HC07,Q15436,Q15392,Q7LGA3,O15258,Q8NCH0,Q14108,P35613,Q12893,Q8TBA6,Q92538,Q86Y82,Q16739,Q92896,P11717,Q08379,O43505,Q8IV08,Q9Y3Q3,Q9Y3B3,O00461,P53367,P62820,P11166,P49257,Q9UL25
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,257,5,384,509,138,21,285,286,288,291,295,168,307,304,61,204,208,85,84,214,350,475,476,474,92,94,221,471,344,100,368,367,101,237,359,491,119,517
|
1333,101,750,1119,683,1407,208,1681,344,1793,1726,1476,2086,168,1479,2116,537,384,491,221,1574,1797,5,291,214,666,2091,2316,1614,881,691,119,692,1497,1735,509,237,1126,843,2004,1737,2304,1701,764,359,2008,527,471,1619,138,1314,257,350,1741,923,617,84,584,2135,797,698,61,304,92,204,1285,474,100,285,286,1110,85,1663,128,475,1460,476,94,747,1004,1597,704,899,307,1042,627,1723,1916,288,748,903,1990,517,1563,21,1678,1403,367,368,295
|
-0.1430695347463049,1.8961668597006474,0.3013170110599651,0.020605480698360126,0.3739010819588171,-0.1994350717264357,1.2107906833937936,-0.4043641190777143,0.8200789823454424,-0.4960569056469889,-0.4346601796282852,-0.2567482190180186,-0.7864806683003362,1.3715614817905903,-0.2567482190180186,-0.8202718560579666,0.5372180454514659,0.7570047251940325,0.6047569844332618,1.1738760097490326,-0.3150370549937861,-0.4960569056469889,3.8314985860427604,0.9625009483378237,1.192389231232484,0.3977415176858454,-0.7864806683003362,-1.2525962685132521,-0.34455645734238355,0.20197116058474252,0.3739010819588171,1.7468979457042964,0.3739010819588171,-0.2567482190180186,-0.4346601796282852,0.58240161346863,1.117653769245169,0.020605480698360126,0.22708991471684983,-0.6869921898793442,-0.4346601796282852,-1.214542773220608,-0.4043641190777143,0.3013170110599651,0.7991941651751763,-0.6869921898793442,0.5598892765754294,0.6269572845849924,-0.34455645734238355,1.6056618506283145,-0.11523365842189977,1.0603817720347808,0.8200789823454424,-0.4346601796282852,0.17666003360338126,0.44490440798943937,2.119881427808456,0.49139101679695213,-0.8202718560579666,0.27676037958362715,0.3739010819588171,2.4130652487639477,0.9425484828699386,2.024171009993822,1.2290815354843998,-0.08762466761145592,0.6269572845849924,1.9106764725104468,0.9823261264765617,0.9823261264765617,0.047126781746465576,2.119881427808456,-0.3743308591385381,1.6535024833174539,0.6269572845849924,-0.22797146657486117,0.6269572845849924,1.9821392383520264,0.3256911134093675,0.1254502957539166,-0.3150370549937861,0.3739010819588171,0.20197116058474252,0.9425484828699386,0.09954637705818221,0.44490440798943937,-0.4043641190777143,-0.590226648688484,0.9823261264765617,0.3256911134093675,0.20197116058474252,-0.65444091817572,0.58240161346863,-0.2857688748733796,3.129814463490708,-0.3743308591385381,-0.17113556168396907,0.7991941651751763,0.7991941651751763,0.9625009483378237
| 2,468
|
Mitotic g2 g2 m phases
| 31
| 79
| 3.464481
| 0.000531
|
O00231,Q9UL46,P60900,Q99436,O43242,Q15154,P07437,P51665,P43034,P49721,P61289,P28074,Q15691,O95684,P68371,Q9BVA1,Q13561,P30153,P30154,P20618,P04350,P61981,P63208,P24941,P28070,Q14203,P49720,O75935,Q15008,Q9H6D7,P28072
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
251,147,408,164,533,165,299,557,556,56,436,54,313,60,312,458,328,326,450,202,333,600,470,224,225,498,230,108,499,118,373
|
251,1266,2221,1226,836,533,1640,108,60,333,1758,781,299,732,956,1057,1155,756,202,224,1059,1532,1158,1305,1199,225,373,54,326,450,1872,760,556,1240,1093,230,56,557,994,408,1737,1063,436,600,1936,845,1279,996,884,887,737,470,312,821,963,695,1622,328,2269,618,1211,498,1213,2215,499,165,313,2078,164,1177,1362,726,1180,458,118,1670,147,2019,1265
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.22708991471684983,0.5372180454514659,-0.3743308591385381,1.8373833245061917,2.43714387569957,0.8614368152158327,-0.46522306940850683,0.27676037958362715,0.9425484828699386,0.3256911134093675,0.15115395482942545,0.07343946733113242,-0.006127331605984542,0.3013170110599651,1.2290815354843998,1.1552498319919475,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,0.8819129546814536,0.6490043765907978,-0.5585543448403263,0.3013170110599651,0.5143859578494419,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,-0.4346601796282852,0.07343946733113242,0.6709000913867084,0.4682311897943023,-0.6221873063453945,0.22708991471684983,-0.08762466761145592,0.1254502957539166,0.20197116058474252,0.20197116058474252,0.3256911134093675,0.6269572845849924,0.9224673008330843,0.25201882658425456,0.15115395482942545,0.3739010819588171,-0.34455645734238355,0.8819129546814536,-1.1026963504909864,0.44490440798943937,-0.033074608598505244,0.6047569844332618,-0.033074608598505244,-0.958720173237647,0.6047569844332618,1.4061522919477702,0.9224673008330843,-0.7530070814189461,1.4232989777185565,-0.006127331605984542,-0.1430695347463049,0.34988503514948976,-0.006127331605984542,0.6490043765907978,1.7621766159448307,-0.3743308591385381,1.5406396934742081,-0.6869921898793442,-0.06023936284890438
| 2,468
|
Anion transmembrane transport
| 10
| 40
| 3.429257
| 0.000605
|
Q8TB61,P08183,P21796,P45880,P53985,Q9UHG3,P33527,Q9H2D1,Q9Y619,P04920
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,32,4,7,40,10,75,14,125,187
|
534,1054,1411,2056,1121,187,2157,1963,32,1481,811,1612,4,75,7,2392,2066,40,1245,2070,1803,453,1655,1544,1507,128,1715,1778,14,1433,1633,834,1042,199,10,1297,275,518,1404,125
|
0.5372180454514659,0.07343946733113242,-0.1994350717264357,-0.7530070814189461,0.020605480698360126,1.2833019254548965,-0.8543859267849101,-0.65444091817572,2.908601987092757,-0.2567482190180186,0.25201882658425456,-0.34455645734238355,3.838410894509741,2.199400481282764,3.6667004853346468,-1.6138737694884546,-0.7530070814189461,2.827005651000117,-0.06023936284890438,-0.7530070814189461,-0.4960569056469889,0.6490043765907978,-0.3743308591385381,-0.2857688748733796,-0.2567482190180186,1.6535024833174539,-0.4043641190777143,-0.46522306940850683,3.3671029220870046,-0.1994350717264357,-0.34455645734238355,0.25201882658425456,0.09954637705818221,1.2472629393969026,3.489782484645634,-0.08762466761145592,1.0216002256059087,0.58240161346863,-0.17113556168396907,1.6692773995529553
| 2,468
|
Lipid localization
| 16
| 57
| 3.299155
| 0.00097
|
P08183,P35610,Q8WTV0,O43772,Q9H6V9,P30536,P35790,P33527,P04062,Q9BQE5,Q14108,P07814,P23786,Q16739,Q9BZF1,P07602
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,255,38,37,103,73,11,75,236,20,84,244,26,92,264,31
|
2400,977,37,534,1053,1229,1996,2373,236,1757,1829,31,536,244,32,491,277,609,1797,2118,26,1490,1999,73,1835,75,255,11,691,1100,451,84,541,92,1507,2203,1141,474,2142,38,398,624,830,443,20,2015,2300,264,1182,103,628,1916,1011,1786,1263,651,1918
|
-1.6991112558978363,0.1254502957539166,2.857903513986415,0.5372180454514659,0.07343946733113242,-0.06023936284890438,-0.6869921898793442,-1.4895231624354457,1.117653769245169,-0.46522306940850683,-0.5271658967301447,2.908601987092757,0.5372180454514659,1.0795911798832665,2.908601987092757,0.6047569844332618,1.0020254240102997,0.44490440798943937,-0.4960569056469889,-0.8202718560579666,2.9583317443973955,-0.2567482190180186,-0.6869921898793442,2.238325990048142,-0.5271658967301447,2.199400481282764,1.0603817720347808,3.4495636506059366,0.3739010819588171,0.047126781746465576,0.6490043765907978,2.119881427808456,0.5372180454514659,2.024171009993822,-0.2567482190180186,-0.9236044800386676,0.020605480698360126,0.6269572845849924,-0.8202718560579666,2.857903513986415,0.7356968204452725,0.44490440798943937,0.25201882658425456,0.6709000913867084,3.139012561494263,-0.6869921898793442,-1.1768795353111265,1.0603817720347808,-0.006127331605984542,1.8961668597006474,0.44490440798943937,-0.590226648688484,0.1254502957539166,-0.46522306940850683,-0.06023936284890438,0.42140856532916043,-0.590226648688484
| 2,468
|
Transporter activity
| 36
| 145
| 3.292303
| 0.000994
|
Q8TB61,Q99595,Q70HW3,P21796,Q8NBU5,P45880,Q9UDW1,Q8IXU6,Q9H2D1,Q6NT16,O75964,Q9Y277,Q9NS69,Q8N4V1,P08183,Q8WTV0,O43772,P53985,Q7L0J3,Q9HC07,O43676,Q9HD20,Q9Y487,P39210,P04920,Q9UBX3,P30536,Q93050,P33527,Q9C0H2,P04062,Q13423,Q9BZF1,O96000,Q9Y619,O15173
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,2,3,4,262,7,136,13,14,15,143,275,29,286,32,38,37,40,41,307,46,47,181,176,187,199,73,76,75,89,236,117,264,122,125,126
|
1333,1567,2151,485,977,126,46,1637,37,534,1728,2323,371,1922,1411,2225,143,1477,554,489,2403,1300,1995,1121,122,1019,324,236,187,981,1642,2157,1480,1829,1965,32,1481,2057,537,1572,491,811,1612,1154,434,609,1689,1690,2255,914,2171,4,1797,394,757,2211,1490,2390,73,663,75,666,1346,1534,524,176,7,2427,691,692,992,2392,842,1616,2066,40,1245,2298,1246,2068,1702,2399,2008,2070,601,1803,998,117,2133,453,999,1283,1544,2370,1168,1507,439,15,2103,1141,1945,3,41,13,286,262,2181,128,38,1256,76,2011,624,830,746,2,342,1910,1715,1718,1778,2300,264,89,863,14,1366,1433,1633,307,834,47,29,199,136,1560,1117,1297,1563,530,275,518,181,125,309
|
-0.1430695347463049,-0.3150370549937861,-0.8543859267849101,0.6047569844332618,0.1254502957539166,1.6535024833174539,2.644730419435073,-0.3743308591385381,2.857903513986415,0.5372180454514659,-0.4346601796282852,-1.2910471139088535,0.7781699552447922,-0.6221873063453945,-0.1994350717264357,-0.994181179090294,1.5733299672243768,-0.2567482190180186,0.5143859578494419,0.6047569844332618,-1.742458928246437,-0.11523365842189977,-0.6869921898793442,0.020605480698360126,1.6849676739945763,0.09954637705818221,0.8819129546814536,1.117653769245169,1.2833019254548965,0.1254502957539166,-0.3743308591385381,-0.8543859267849101,-0.2567482190180186,-0.5271658967301447,-0.65444091817572,2.908601987092757,-0.2567482190180186,-0.7530070814189461,0.5372180454514659,-0.3150370549937861,0.6047569844332618,0.25201882658425456,-0.34455645734238355,-0.006127331605984542,0.6709000913867084,0.44490440798943937,-0.4043641190777143,-0.4043641190777143,-1.066163090613305,0.17666003360338126,-0.8888282886905626,3.838410894509741,-0.4960569056469889,0.7356968204452725,0.3013170110599651,-0.958720173237647,-0.2567482190180186,-1.6138737694884546,2.238325990048142,0.3977415176858454,2.199400481282764,0.3977415176858454,-0.1430695347463049,-0.2857688748733796,0.5598892765754294,1.3189165219976549,3.6667004853346468,-2.156313870988057,0.3739010819588171,0.3739010819588171,0.1254502957539166,-1.6138737694884546,0.22708991471684983,-0.34455645734238355,-0.7530070814189461,2.827005651000117,-0.06023936284890438,-1.1768795353111265,-0.06023936284890438,-0.7530070814189461,-0.4043641190777143,-1.6562527119273847,-0.6869921898793442,-0.7530070814189461,0.4682311897943023,-0.4960569056469889,0.1254502957539166,1.7773752159481948,-0.8202718560579666,0.6490043765907978,0.1254502957539166,-0.08762466761145592,-0.2857688748733796,-1.4489724671135231,-0.006127331605984542,-0.2567482190180186,0.6709000913867084,3.3248211178078995,-0.7864806683003362,0.020605480698360126,-0.6221873063453945,4.09320199924866,2.827005651000117,3.383816314422708,0.9823261264765617,1.0603817720347808,-0.8888282886905626,1.6535024833174539,2.857903513986415,-0.06023936284890438,2.199400481282764,-0.6869921898793442,0.44490440798943937,0.25201882658425456,0.3256911134093675,4.0993803881071775,0.8408260074769911,-0.590226648688484,-0.4043641190777143,-0.4043641190777143,-0.46522306940850683,-1.1768795353111265,1.0603817720347808,2.0518497400362734,0.22708991471684983,3.3671029220870046,-0.1430695347463049,-0.1994350717264357,-0.34455645734238355,0.9425484828699386,0.25201882658425456,2.6224404188956902,2.928608323075618,1.2472629393969026,1.6216955230183503,-0.2857688748733796,0.047126781746465576,-0.08762466761145592,-0.2857688748733796,0.5598892765754294,1.0216002256059087,0.58240161346863,1.3189165219976549,1.6692773995529553,0.9425484828699386
| 2,468
|
Inorganic anion transport
| 10
| 22
| 3.268695
| 0.00108
|
P08183,P21796,P45880,Q9UBX3,P30536,Q9UHG3,P33527,P54105,Q9C0H2,P04920
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,4,7,199,73,10,75,151,89,187
|
1567,1637,187,32,537,4,73,75,7,2392,151,1245,2070,1803,1507,439,89,1365,199,10,275,518
|
-0.3150370549937861,-0.3743308591385381,1.2833019254548965,2.908601987092757,0.5372180454514659,3.838410894509741,2.238325990048142,2.199400481282764,3.6667004853346468,-1.6138737694884546,1.5075840575864408,-0.06023936284890438,-0.7530070814189461,-0.4960569056469889,-0.2567482190180186,0.6709000913867084,2.0518497400362734,-0.1430695347463049,1.2472629393969026,3.489782484645634,1.0216002256059087,0.58240161346863
| 2,468
|
Mitotic g1 phase and g1 s transition
| 27
| 67
| 3.25137
| 0.001149
|
O00231,Q07864,P31350,Q9UL46,P33991,P60900,Q00534,Q99436,O43242,P61289,P49736,P49721,P28074,P30154,P30153,P20618,Q14566,P00374,P63208,P33993,P24941,P28070,P11802,P49720,Q15008,P28072,Q9Y619
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
251,526,523,147,405,408,421,164,533,436,435,56,54,450,326,202,452,79,470,468,224,225,223,230,499,373,125
|
251,1266,2221,1226,533,1228,1640,79,1194,781,1894,2241,223,982,1057,756,202,224,633,1059,1532,1158,1305,1022,1199,225,373,54,326,450,523,405,1060,468,1872,1240,1093,917,230,56,435,557,994,408,436,845,1279,884,887,470,421,821,526,963,695,696,676,2269,452,499,2216,164,1177,1721,147,1265,125
|
1.0603817720347808,-0.08762466761145592,-0.994181179090294,-0.06023936284890438,0.5372180454514659,-0.06023936284890438,-0.3743308591385381,2.1599235408173723,-0.033074608598505244,0.27676037958362715,-0.590226648688484,-1.0299934512102915,1.1552498319919475,0.1254502957539166,0.07343946733113242,0.3013170110599651,1.2290815354843998,1.1552498319919475,0.42140856532916043,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,0.09954637705818221,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,0.8819129546814536,0.6490043765907978,0.5598892765754294,0.7142445586094798,0.07343946733113242,0.6269572845849924,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,0.17666003360338126,1.1365094929601929,2.4964247239663777,0.6709000913867084,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.20197116058474252,0.6269572845849924,0.692646228876154,0.25201882658425456,0.5598892765754294,0.15115395482942545,0.3739010819588171,0.3739010819588171,0.3977415176858454,-1.1026963504909864,0.6490043765907978,0.6047569844332618,-0.958720173237647,1.4232989777185565,-0.006127331605984542,-0.4043641190777143,1.5406396934742081,-0.06023936284890438,1.6692773995529553
| 2,468
|
Proteasome degradation
| 14
| 39
| 3.234597
| 0.001218
|
P28070,Q99436,O00231,P10321,O43242,P49720,P20618,Q15008,Q9UL46,P61289,P49721,P60900,P28072,P28074
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
225,164,251,384,533,230,202,499,147,436,56,408,373,54
|
251,1266,1226,533,1640,1479,1231,1195,384,756,202,984,1059,1532,1158,1305,1199,225,373,54,1872,1240,1093,230,56,557,994,408,436,845,1279,884,821,695,499,164,1177,147,1265
|
1.0603817720347808,-0.08762466761145592,-0.06023936284890438,0.5372180454514659,-0.3743308591385381,-0.2567482190180186,-0.06023936284890438,-0.033074608598505244,0.7570047251940325,0.3013170110599651,1.2290815354843998,0.1254502957539166,0.07343946733113242,-0.2857688748733796,-0.006127331605984542,-0.11523365842189977,-0.033074608598505244,1.1552498319919475,0.7781699552447922,2.4964247239663777,-0.5585543448403263,-0.06023936284890438,0.047126781746465576,1.1365094929601929,2.4964247239663777,0.5143859578494419,0.1254502957539166,0.7142445586094798,0.6709000913867084,0.22708991471684983,-0.08762466761145592,0.20197116058474252,0.25201882658425456,0.3739010819588171,0.6047569844332618,1.4232989777185565,-0.006127331605984542,1.5406396934742081,-0.06023936284890438
| 2,468
|
Lipid binding
| 36
| 106
| 3.214094
| 0.001309
|
A6NIH7,P21796,O43633,P35610,P45880,O14773,Q9BQE5,P07602,O95218,Q9UNH7,Q8N668,Q8WTV0,P21359,O00429,O95772,P09429,P30536,Q9H6U6,Q8IYI6,Q14108,Q9Y4G8,Q15067,Q8NCC3,Q92538,P11717,P28070,O60749,O94788,Q86YQ8,P04062,P53367,O14964,P50897,Q13045,Q9BZF1,O15173
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
1,4,504,255,7,141,20,31,290,428,292,38,415,412,51,319,73,480,211,84,484,340,88,476,221,225,464,102,500,236,237,487,112,248,264,126
|
1,570,412,1568,141,487,870,977,126,684,504,1409,553,1638,464,953,1961,102,1682,290,51,236,1757,981,1829,31,1272,1965,319,1444,2324,1445,2294,221,1485,1833,415,4,1797,2118,1059,225,1999,1575,73,611,255,612,1534,7,1276,1162,691,112,1205,1536,1736,237,1699,1838,737,1100,1030,248,1065,84,742,2135,340,1505,2074,2178,1170,857,500,211,292,88,38,476,895,1461,2299,2049,830,2288,1910,1222,1143,20,2015,2300,264,1365,1598,480,628,1956,1263,1331,530,428,1403,1866,484,1790
|
4.1239287394808555,0.49139101679695213,0.692646228876154,-0.3150370549937861,1.5895402794086952,0.6047569844332618,0.20197116058474252,0.1254502957539166,1.6535024833174539,0.3739010819588171,0.58240161346863,-0.1994350717264357,0.5143859578494419,-0.3743308591385381,0.6269572845849924,0.15115395482942545,-0.65444091817572,1.8961668597006474,-0.4043641190777143,0.9625009483378237,2.5544363806012425,1.117653769245169,-0.46522306940850683,0.1254502957539166,-0.5271658967301447,2.908601987092757,-0.08762466761145592,-0.65444091817572,0.9022559500015589,-0.22797146657486117,-1.2910471139088535,-0.22797146657486117,-1.1768795353111265,1.1738760097490326,-0.2567482190180186,-0.5271658967301447,0.692646228876154,3.838410894509741,-0.4960569056469889,-0.8202718560579666,0.07343946733113242,1.1552498319919475,-0.6869921898793442,-0.3150370549937861,2.238325990048142,0.44490440798943937,1.0603817720347808,0.44490440798943937,-0.2857688748733796,3.6667004853346468,-0.08762466761145592,-0.006127331605984542,0.3739010819588171,1.807535106013106,-0.033074608598505244,-0.2857688748733796,-0.4346601796282852,1.117653769245169,-0.4043641190777143,-0.5271658967301447,0.3256911134093675,0.047126781746465576,0.09954637705818221,1.0795911798832665,0.07343946733113242,2.119881427808456,0.3256911134093675,-0.8202718560579666,0.8408260074769911,-0.2567482190180186,-0.7530070814189461,-0.8888282886905626,-0.006127331605984542,0.22708991471684983,0.6047569844332618,1.2107906833937936,0.9625009483378237,2.065588110324613,2.857903513986415,0.6269572845849924,0.20197116058474252,-0.22797146657486117,-1.1768795353111265,-0.7198459356446938,0.25201882658425456,-1.139599641176551,-0.590226648688484,-0.033074608598505244,0.020605480698360126,3.139012561494263,-0.6869921898793442,-1.1768795353111265,1.0603817720347808,-0.1430695347463049,-0.3150370549937861,0.6269572845849924,0.44490440798943937,-0.6221873063453945,-0.06023936284890438,-0.11523365842189977,0.5598892765754294,0.692646228876154,-0.17113556168396907,-0.5271658967301447,0.6269572845849924,-0.46522306940850683
| 2,468
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