term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Translocation
| 24
| 45
| 3.185791
| 0.001444
|
Q9NS69,Q99595,P37198,Q9Y5J9,P57740,P61970,Q8NFH4,Q9P2E9,Q7Z3B4,Q15629,O43615,O75381,Q8TD16,Q12769,Q9Y5J7,Q92621,Q99567,Q9BTX1,P49792,O14925,Q8NFH5,Q8N1F7,Q9BVV7,P12270
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
0,2,133,400,658,23,291,428,557,43,549,301,313,566,317,705,707,202,594,344,739,238,634,370
|
1809,344,549,301,1610,370,733,133,1713,594,1526,985,658,2536,1563,23,2238,566,43,1043,1721,1044,557,238,291,739,313,1091,928,1395,705,804,707,2,202,1050,634,1000,1605,0,428,1513,1144,317,400
|
-0.4285902586631195,0.9612662003264605,0.5720990698697436,1.1073832487263275,-0.31037139890127774,0.9072221686279333,0.32257915315367963,1.9384826617323367,-0.36074150382824394,0.5143375851029162,-0.26043517265107846,0.09320779573109034,0.42661358757948437,-1.0971550435827746,-0.27703285170862874,3.106106395795426,-0.7082376548394596,0.5577119571515898,2.7878758792557337,0.04623097246479662,-0.36074150382824394,0.04623097246479662,0.5720990698697436,1.3263238911225568,1.1596327314267856,0.32257915315367963,1.0678905729851498,0.014701291299391921,0.13980900706892938,-0.17815150752877743,0.3673920803157548,0.24711890736266962,0.3673920803157548,4.084595663215114,1.4761368247888418,0.04623097246479662,0.4706398114973275,0.09320779573109034,-0.29367816551779385,4.48719359410752,0.7976231963964028,-0.243884846085324,-0.017000063987738737,1.0546674241385827,0.8663612864956289
| 2,702
|
Protein localization to mitochondrion
| 21
| 51
| 3.150689
| 0.001629
|
Q9NS69,Q99595,O95831,O14737,Q10713,Q9Y5J9,P55786,P30536,Q5JRX3,O43615,Q9Y5J7,P31749,Q8N4H5,Q15070,P51572,O14925,Q8TB36,Q53H12,Q15388,Q9P0J0,Q9Y6C9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,2,9,265,397,400,28,289,295,549,317,189,72,85,469,344,484,237,366,375,509
|
1219,2148,1099,265,344,549,1734,1225,1296,9,785,1551,2133,862,2196,2560,1004,289,1326,189,2372,1327,469,1681,28,2394,397,85,366,1043,237,295,2164,72,484,1621,805,2,764,634,1139,1374,0,375,2364,1758,569,663,317,400,509
|
-0.08092564237043719,-0.6370462182791121,-0.001127805810301048,1.237151067189716,0.9612662003264605,0.5720990698697436,-0.377629316099032,-0.08092564237043719,-0.12933524422973913,3.601980510099323,0.2622891279230963,-0.27703285170862874,-0.6193847456466299,0.2013703373493341,-0.6725321288961622,-1.1549278473496636,0.07759089922445578,1.1596327314267856,-0.14556179771058245,1.549648138953408,-0.8533136017184143,-0.14556179771058245,0.7140629338857863,-0.3439027766845685,3.0018786097104724,-0.8717077957387307,0.8663612864956289,2.314254726861213,0.9207797152191141,0.04623097246479662,1.3263238911225568,1.1466136121023172,-0.6370462182791121,2.420435656490256,0.6859434192423728,-0.31037139890127774,0.24711890736266962,4.084595663215114,0.2925118928589216,0.4706398114973275,-0.017000063987738737,-0.1618337970909173,4.48719359410752,0.9072221686279333,-0.8349780072652183,-0.377629316099032,0.5577119571515898,0.42661358757948437,1.0546674241385827,0.8663612864956289,0.6435101106197167
| 2,702
|
Nuclear membrane
| 25
| 54
| 3.13197
| 0.001736
|
O00560,Q03252,P37198,Q5JTV8,Q8IXM6,Q96PE3,P67812,Q9UH99,Q14739,Q9H1E5,P20700,Q9Y2U8,O75976,O94919,P56134,Q9BTX1,P49792,Q6UW68,P12270,Q8WXH0,P50402,O15260,O95619,Q96G23,O14735
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
637,391,133,651,404,292,165,560,175,177,309,581,314,571,573,202,594,98,370,506,233,109,246,120,379
|
637,379,1077,109,1549,1610,314,571,731,246,2193,1816,370,2026,309,133,2001,1713,594,233,573,658,165,391,175,1010,651,98,1283,1136,404,1945,739,928,506,1395,120,292,872,1030,1601,202,1755,177,1605,1172,560,1757,1894,1144,581,1846,1585,709
|
0.4560011507642696,0.8936333486288025,0.014701291299391921,2.0626573264796644,-0.27703285170862874,-0.31037139890127774,1.0546674241385827,0.5432894598416556,0.32257915315367963,1.3009827009421377,-0.6725321288961622,-0.4285902586631195,0.9072221686279333,-0.5492740993843713,1.0810841689575286,1.9384826617323367,-0.5318785727630885,-0.36074150382824394,0.5143375851029162,1.338953943492325,0.5432894598416556,0.42661358757948437,1.717718863168589,0.8800131050184969,1.658237345935038,0.07759089922445578,0.4413258066063131,2.206160580984627,-0.11315387381905866,-0.017000063987738737,0.852677740649789,-0.4972437792285436,0.32257915315367963,0.13980900706892938,0.6435101106197167,-0.17815150752877743,1.9952458014491112,1.1596327314267856,0.2013703373493341,0.061932036437784624,-0.29367816551779385,1.4761368247888418,-0.377629316099032,1.6462693525823706,-0.29367816551779385,-0.032915728384741015,0.5720990698697436,-0.377629316099032,-0.462815185693309,-0.017000063987738737,0.5432894598416556,-0.4285902586631195,-0.27703285170862874,0.3673920803157548
| 2,702
|
Alcohol binding
| 7
| 14
| 3.114332
| 0.001844
|
O15118,P30536,P45880,Q9H4L5,P21796,P61916,Q14108
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
63,289,34,358,11,248,29
|
379,63,887,1250,1323,11,1353,1711,289,34,248,29,1784,358
|
0.8936333486288025,2.472830381816948,0.17067086843316673,-0.09701742595051951,-0.14556179771058245,3.541068752096914,-0.1618337970909173,-0.36074150382824394,1.1596327314267856,2.953902538225382,1.3009827009421377,3.0018786097104724,-0.3945665116133365,0.9478015835630615
| 2,702
|
Exopeptidase activity
| 12
| 28
| 3.107064
| 0.00189
|
Q9HB40,P10619,P42785,P36551,Q9H3G5,O75844,Q92820,O14773,Q9NZ08,P55786,O75976,Q9UIQ6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
6,38,12,269,18,147,284,150,250,28,314,64
|
150,147,314,665,540,38,2669,2506,2029,269,12,28,2537,1334,2494,1134,284,1342,1285,1601,18,2269,6,332,932,2129,250,64
|
1.8349285964616746,1.858096452664984,1.0546674241385827,0.41186430071853863,0.5864509778300103,2.8665746612984697,-1.7457215321911723,-1.0399582580540272,-0.5492740993843713,1.224301699534718,3.523552992410392,3.0018786097104724,-1.0971550435827746,-0.14556179771058245,-1.0021412347204408,-0.017000063987738737,1.1855852561088989,-0.14556179771058245,-0.11315387381905866,-0.29367816551779385,3.2820201142446788,-0.7261736594651729,3.9059864908023467,1.0014765288625636,0.13980900706892938,-0.6017771358819511,1.3009827009421377,2.472830381816948
| 2,702
|
Glycosphingolipid metabolism
| 8
| 15
| 3.105977
| 0.001897
|
P07686,P17900,P07602,P10619,P06280,Q13510,P06865,P16278
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,162,4,38,112,26,92,93
|
636,467,188,112,92,4,160,38,93,162,26,2671,1372,1172,427
|
0.4560011507642696,0.7140629338857863,1.549648138953408,2.040271181152975,2.249632405350508,4.00405433878558,1.7531245573462935,2.8665746612984697,2.2387939765464413,1.7295441678744543,3.0114283478612625,-1.7672271447732948,-0.1618337970909173,-0.032915728384741015,0.7976231963964028
| 2,702
|
Transporters
| 131
| 336
| 3.103273
| 0.001914
|
Q70HW3,Q8NHH9,P07602,Q99720,P33527,Q96JJ7,P24390,Q8NE01,Q9HD26,Q13190,Q14108,Q5VW38,Q9C0H2,P45880,P05023,Q6NT16,Q9UH99,Q96QD8,Q8IY95,Q15629,Q7Z3B4,Q16891,Q5BJF2,O60637,Q07021,P46977,Q9H2D1,P08183,Q8NB49,Q9Y371,Q12769,Q9NQZ5,Q8IXU6,O15118,P20674,Q9HD20,Q9NR77,Q8N4V1,Q6ZXV5,Q93050,O43772,Q15287,Q15070,P49792,P33176,P52292,Q9NRR5,Q9BXP2,Q6P4A7,Q6UW68,Q96HV5,Q969E2,O15260,P28288,P12236,Q8TCT8,Q99808,P50995,Q6NUK1,Q9Y3B3,O00560,A0FGR8,O14681,P37198,O60443,P57088,Q9NUQ8,Q9UBX3,O96005,Q9BQT8,O75844,Q9Y512,P57740,Q8NEW0,Q9H2V7,Q9UGP8,Q96S66,P02786,Q96PC5,Q07065,P31749,Q9H3N1,O43865,Q9H2H9,Q9BTX1,Q9UBU6,Q9Y619,Q8N1F7,P61916,Q8TB61,P53985,P40855,Q8NFH4,O75381,Q9BPX6,Q9Y6M7,O75027,Q8WTV0,O60313,O15127,P35613,Q96L92,O43808,P00403,Q13555,O00400,O95202,Q8IWA4,Q15363,P12270,Q9UBV2,O15439,Q9BUR5,P11279,P13073,Q9BUN8,P11717,Q9UJS0,Q9NZJ7,O75955,P57105,Q92973,Q96A33,P16615,P41440,P51572,O43681,Q8TEX9,Q15904,Q9Y6C9,P04920
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
1,518,4,5,13,523,15,521,538,532,29,30,31,34,539,37,560,559,558,43,557,555,47,49,553,563,53,54,567,569,566,60,61,63,572,69,78,79,599,82,83,597,85,594,593,90,611,609,97,98,622,621,109,615,614,118,633,630,642,130,637,636,638,133,645,649,654,144,145,146,147,663,658,152,153,674,669,665,172,179,189,191,196,198,202,205,226,238,248,258,271,288,291,301,303,304,312,324,326,325,328,331,337,338,346,352,363,373,372,370,384,380,393,387,395,413,417,420,427,422,431,434,442,441,457,469,467,492,488,509,502
|
636,1809,2352,2055,352,664,1606,1099,2310,637,742,814,638,1404,1635,1077,63,2022,325,1453,109,1002,380,1122,2610,467,1959,83,337,196,326,1706,645,956,49,2087,1379,312,2326,2404,301,2430,887,1610,921,147,1637,422,2354,1250,2212,798,363,1735,1078,1349,1151,1961,145,785,338,2432,665,2257,818,2487,1198,859,1228,502,539,1252,860,957,1080,1229,4,1323,54,1057,1298,976,977,1175,889,1519,387,417,978,614,370,395,1642,1430,441,1996,1022,1676,572,1101,2406,2407,1431,941,15,615,2298,189,593,13,328,733,1082,2153,133,1876,1024,2000,288,457,34,2001,2434,563,1327,1878,701,1969,1713,594,755,630,1410,469,1463,90,1235,1526,756,271,787,1821,1274,2094,985,649,431,658,2536,986,2345,1970,841,1563,1822,248,1766,865,1940,1041,2238,2656,2320,1854,1595,2692,1278,2115,2035,2567,1159,553,179,909,757,1437,1494,566,1616,788,532,346,2285,1596,29,1795,1206,1010,927,85,597,372,43,1415,488,683,2556,555,760,47,869,695,1044,30,830,2657,37,963,642,1443,97,98,599,1,557,373,61,558,2624,1046,238,79,1419,567,521,1983,152,291,739,518,1913,258,2011,118,1475,1091,492,324,928,1395,895,705,1397,434,82,621,1342,442,1369,1370,804,1093,622,523,1779,331,1503,847,172,559,780,669,707,5,848,633,303,146,1372,202,765,413,393,1050,1000,609,1169,1784,1448,31,1215,53,198,153,1892,191,873,1629,1700,896,1245,69,538,1095,60,78,1605,611,1013,654,427,969,1484,1581,205,1513,384,144,2638,674,560,1118,1217,2402,2485,420,1485,1144,1376,917,951,1758,1805,935,569,130,1017,1929,663,1703,1704,226,1377,2549,509,304
|
0.4560011507642696,-0.4285902586631195,-0.8349780072652183,-0.566722147958878,0.9478015835630615,0.41186430071853863,-0.31037139890127774,-0.001127805810301048,-0.7803189764195482,0.4560011507642696,0.30756485716682186,0.23190917857868676,0.4560011507642696,-0.19451519653859392,-0.3271128392759249,0.014701291299391921,2.472830381816948,-0.5492740993843713,1.014819277244463,-0.22738159228350283,2.0626573264796644,0.07759089922445578,0.8936333486288025,-0.017000063987738737,-1.331826169509489,0.7140629338857863,-0.514535240785251,2.3249577453845984,0.9747001337238531,1.4884520937953238,1.014819277244463,-0.36074150382824394,0.4413258066063131,0.10878295888408213,2.6577600342457113,-0.5842230489234069,-0.17815150752877743,1.0678905729851498,-0.7984810752691569,-0.8901609796463711,1.1073832487263275,-0.9272458982666049,0.17067086843316673,-0.31037139890127774,0.13980900706892938,1.858096452664984,-0.3271128392759249,0.7976231963964028,-0.8349780072652183,-0.09701742595051951,-0.6903572636353332,0.24711890736266962,0.9207797152191141,-0.377629316099032,0.014701291299391921,-0.1618337970909173,-0.032915728384741015,-0.514535240785251,1.8696467178692489,0.2622891279230963,0.9747001337238531,-0.9272458982666049,0.41186430071853863,-0.7261736594651729,0.23190917857868676,-1.0021412347204408,-0.0648782670729416,0.2013703373493341,-0.08092564237043719,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,0.10878295888408213,0.014701291299391921,-0.08092564237043719,4.00405433878558,-0.14556179771058245,2.5762697271805473,0.030487470396744938,-0.12933524422973913,0.09320779573109034,0.09320779573109034,-0.04887504627384466,0.17067086843316673,-0.26043517265107846,0.8800131050184969,0.8114351982042777,0.09320779573109034,0.48524197874422104,0.9072221686279333,0.8663612864956289,-0.3271128392759249,-0.21092513401942328,0.7699015142883784,-0.5318785727630885,0.061932036437784624,-0.3439027766845685,0.5432894598416556,-0.001127805810301048,-0.8901609796463711,-0.8901609796463711,-0.21092513401942328,0.12431661965225804,3.4883696583674233,0.48524197874422104,-0.7622139544215649,1.549648138953408,0.5143375851029162,3.497184563628806,1.0014765288625636,0.32257915315367963,0.014701291299391921,-0.6370462182791121,1.9384826617323367,-0.462815185693309,0.061932036437784624,-0.5318785727630885,1.1726232359899564,0.7420485262435965,2.953902538225382,-0.5318785727630885,-0.9272458982666049,0.5577119571515898,-0.14556179771058245,-0.462815185693309,0.3673920803157548,-0.514535240785251,-0.36074150382824394,0.5143375851029162,0.2925118928589216,0.4706398114973275,-0.19451519653859392,0.7140629338857863,-0.22738159228350283,2.282030613119506,-0.08092564237043719,-0.26043517265107846,0.2925118928589216,1.211424359795403,0.2622891279230963,-0.4285902586631195,-0.11315387381905866,-0.5842230489234069,0.09320779573109034,0.4413258066063131,0.7837786881907414,0.42661358757948437,-1.0971550435827746,0.09320779573109034,-0.8167006259673601,-0.514535240785251,0.21665972726603153,-0.27703285170862874,-0.4285902586631195,1.3009827009421377,-0.3945665116133365,0.2013703373493341,-0.4972437792285436,0.04623097246479662,-0.7082376548394596,-1.5974159851662177,-0.7803189764195482,-0.4456774203599463,-0.29367816551779385,-4.69941189821712,-0.11315387381905866,-0.6017771358819511,-0.5492740993843713,-1.174315546728808,-0.032915728384741015,0.5720990698697436,1.6222608747574856,0.1552603482535626,0.2925118928589216,-0.21092513401942328,-0.243884846085324,0.5577119571515898,-0.31037139890127774,0.2622891279230963,0.6007678594820233,0.9612662003264605,-0.7441656379825385,-0.29367816551779385,3.0018786097104724,-0.4115533912456994,-0.0648782670729416,0.07759089922445578,0.13980900706892938,2.314254726861213,0.5143375851029162,0.9072221686279333,2.7878758792557337,-0.19451519653859392,0.6718330237408522,0.39707775152061925,-1.1356055001499545,0.5720990698697436,0.2925118928589216,2.7381629713773825,0.2013703373493341,0.382253743928895,0.04623097246479662,2.9923137792580112,0.23190917857868676,-1.6183674545716196,2.886090180376803,0.10878295888408213,0.4560011507642696,-0.21092513401942328,2.217058138603211,2.206160580984627,0.5143375851029162,4.343126506682812,0.5720990698697436,0.9072221686279333,2.4832547399290448,0.5720990698697436,-1.3718907863996646,0.04623097246479662,1.3263238911225568,2.3463066784162883,-0.19451519653859392,0.5577119571515898,0.6150498919054735,-0.514535240785251,1.8349285964616746,1.1596327314267856,0.32257915315367963,0.6292972508241202,-0.4800038669191164,1.275532592400303,-0.5318785727630885,2.0065339889232616,-0.22738159228350283,0.014701291299391921,0.6718330237408522,1.0281319155612654,0.13980900706892938,-0.17815150752877743,0.17067086843316673,0.3673920803157548,-0.17815150752877743,0.7837786881907414,2.3356417057869807,0.48524197874422104,-0.14556179771058245,0.7699015142883784,-0.1618337970909173,-0.1618337970909173,0.24711890736266962,0.014701291299391921,0.48524197874422104,0.6150498919054735,-0.3945665116133365,1.0014765288625636,-0.243884846085324,0.21665972726603153,1.6701813099617207,0.5720990698697436,0.2774200528143013,0.41186430071853863,0.3673920803157548,4.00405433878558,0.21665972726603153,0.4706398114973275,1.1073832487263275,1.8696467178692489,-0.1618337970909173,1.4761368247888418,0.2925118928589216,0.8252148517366122,0.8800131050184969,0.04623097246479662,0.09320779573109034,0.4998078409542412,-0.032915728384741015,-0.3945665116133365,-0.21092513401942328,2.9827338068802134,-0.0648782670729416,2.5967459172501477,1.4884520937953238,1.8349285964616746,-0.462815185693309,1.5374592754176952,0.2013703373493341,-0.31037139890127774,-0.3439027766845685,0.17067086843316673,-0.08092564237043719,2.4309512128450095,0.6007678594820233,0.014701291299391921,2.5040493921299296,2.3569527332268905,-0.29367816551779385,0.4998078409542412,0.07759089922445578,0.4413258066063131,0.7976231963964028,0.10878295888408213,-0.22738159228350283,-0.27703285170862874,1.463795947164361,-0.243884846085324,0.8936333486288025,1.8811746612706568,-1.4732988595445302,0.41186430071853863,0.5720990698697436,-0.001127805810301048,-0.0648782670729416,-0.8717077957387307,-0.983325689072196,0.8114351982042777,-0.22738159228350283,-0.017000063987738737,-0.1618337970909173,0.1552603482535626,0.12431661965225804,-0.377629316099032,-0.4115533912456994,0.13980900706892938,0.5577119571515898,1.9612526973306057,0.07759089922445578,-0.4800038669191164,0.42661358757948437,-0.3439027766845685,-0.3439027766845685,1.3766833583434828,-0.1618337970909173,-1.1163480492502467,0.6435101106197167,1.1073832487263275
| 2,702
|
Ion transport
| 24
| 53
| 3.096442
| 0.001959
|
P21796,Q9H0H5,Q8NE01,Q8NEW0,Q9C0H2,P45880,P05023,Q9Y5K8,Q96QD8,Q9Y487,Q9BPX6,Q9Y6M7,Q9Y277,O75964,P16615,P25705,Q9H2H9,Q93050,P06576,O95202,Q15904,P51790,P24539,P04920
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
11,270,521,152,31,34,539,561,559,41,303,304,437,184,441,451,198,82,215,363,488,242,371,502
|
2055,1992,184,363,785,502,539,1252,215,441,1022,1101,2406,11,941,371,451,1614,1082,1876,34,2508,242,1463,1821,573,904,841,1278,1028,488,760,2657,521,1660,152,1475,82,2427,559,669,303,31,270,198,1217,1376,437,1805,41,561,2549,304
|
-0.566722147958878,-0.5318785727630885,1.586065401491409,0.9207797152191141,0.2622891279230963,0.6435101106197167,0.5864509778300103,-0.09701742595051951,1.4017035243632918,0.7699015142883784,0.061932036437784624,-0.001127805810301048,-0.8901609796463711,3.541068752096914,0.12431661965225804,0.9072221686279333,0.7559915142019157,-0.31037139890127774,0.014701291299391921,-0.462815185693309,2.953902538225382,-1.0399582580540272,1.3136668502909221,-0.22738159228350283,-0.4285902586631195,0.5432894598416556,0.1552603482535626,0.21665972726603153,-0.11315387381905866,0.061932036437784624,0.6718330237408522,0.2925118928589216,-1.6183674545716196,0.6150498919054735,-0.3271128392759249,1.8349285964616746,-0.22738159228350283,2.3356417057869807,-0.9086735477231258,0.5720990698697436,0.41186430071853863,1.1073832487263275,2.9827338068802134,1.224301699534718,1.4884520937953238,-0.0648782670729416,-0.1618337970909173,0.7837786881907414,-0.4115533912456994,2.8371826720644844,0.5720990698697436,-1.1163480492502467,1.1073832487263275
| 2,702
|
Organic acid transmembrane transporter activity
| 10
| 21
| 3.094794
| 0.001969
|
O15439,Q9Y619,Q9UJS0,Q9H2H9,P33527,P53985,Q9UBX3,Q9BQT8,Q9H2D1,P08183
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
380,226,420,198,13,271,144,146,53,54
|
380,921,1151,54,1057,13,457,271,1159,1415,1443,1503,559,146,53,198,1629,144,420,1805,226
|
0.8936333486288025,0.13980900706892938,-0.032915728384741015,2.5762697271805473,0.030487470396744938,3.497184563628806,0.7420485262435965,1.211424359795403,-0.032915728384741015,-0.19451519653859392,-0.21092513401942328,-0.243884846085324,0.5720990698697436,1.8696467178692489,2.5967459172501477,1.4884520937953238,-0.31037139890127774,1.8811746612706568,0.8114351982042777,-0.4115533912456994,1.3766833583434828
| 2,702
|
Organelle subcompartment
| 109
| 316
| 3.094062
| 0.001974
|
Q8NHH9,Q99720,P84095,Q9Y4P3,Q96JJ7,P24390,Q9BQE5,Q8IV08,Q53GQ0,Q13190,Q99735,Q14108,Q6NUQ1,P30519,Q8N0U8,Q15629,Q5BJF2,Q10472,P43307,P46977,Q8NB49,Q9P2W9,Q9Y282,Q16850,Q4J6C6,Q9HD20,P07099,Q8TCT9,Q8N4V1,P38435,P52292,Q86XL3,Q70UQ0,Q8NBN3,O15260,Q8TCT8,Q96G23,O00461,Q9Y3B3,Q8N2H4,Q9Y5M8,O95197,O75844,Q9NPR9,P37268,O00264,P67812,Q15392,Q96PC5,Q14739,Q07065,P04062,O43852,Q9H3N1,O43865,O60725,Q9UBU6,Q06136,P50402,Q9NZ08,Q8TB61,Q96HY6,P51648,O95470,Q6NUM9,Q9BRR6,Q9NQC3,Q14534,Q9BV10,O15127,P35613,P09601,Q13555,Q9UBM7,Q9H4L5,O00400,O95249,Q15800,Q15363,Q9UBV2,O14735,Q9BUR5,P16435,O95070,P48449,Q10713,Q9BTU6,Q8NF37,Q9BUN8,O15269,P11717,Q14789,Q9P2E9,P10321,Q8N2K0,Q6P1A2,O14578,O75122,Q96A33,Q96KC8,P16615,O95674,A1L0T0,Q9NX62,Q9P035,P51572,Q16706,Q15904,Q8WXH0
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
518,5,514,528,523,15,16,19,535,532,545,29,542,35,40,43,47,554,51,563,567,59,62,65,66,69,70,77,79,86,90,102,103,108,109,118,120,126,130,132,136,142,147,155,154,159,165,166,172,175,179,188,190,191,196,201,205,204,233,250,258,272,277,275,283,298,308,311,320,325,328,334,346,359,358,352,364,367,372,384,379,393,388,386,396,397,399,405,413,415,417,418,428,423,425,424,421,430,442,445,441,438,448,454,455,469,478,488,506
|
636,448,159,352,1099,2190,126,2463,637,973,421,710,638,379,1635,1488,1018,1759,2022,325,109,415,1454,1489,1122,1959,1550,190,196,1732,656,201,1490,430,2326,1733,887,1609,147,1637,1174,876,1250,798,386,142,364,1735,2256,275,2389,901,1427,438,799,2431,188,2487,859,1228,1080,70,2313,1380,976,977,334,423,417,890,388,441,819,979,1676,2407,1555,2505,15,1492,1998,1408,2506,2451,1302,35,1381,1326,1849,1234,328,154,86,2000,1819,604,51,2434,563,1460,396,982,1765,1327,1878,701,1969,233,755,1201,2375,469,277,90,822,2156,2376,2178,2094,985,649,2536,1006,2283,1794,2137,823,1905,2420,1563,1822,1823,1939,865,2422,2238,165,514,1278,2035,961,1882,1528,2691,1026,204,179,2694,1062,554,1494,397,1616,788,1133,1084,532,346,1566,1617,29,1440,311,175,418,1010,724,927,1442,1335,372,166,2138,1064,43,2043,367,488,478,65,867,66,535,47,869,695,2222,2008,2204,1750,963,283,542,802,424,1443,1691,1164,103,2494,684,667,620,102,870,19,1110,40,1946,132,425,79,1500,1419,1862,567,727,108,405,715,518,1211,258,2011,2292,118,77,1475,1091,2012,914,506,929,716,659,1397,621,777,1342,442,1369,965,120,1093,272,523,2126,445,172,1447,669,1863,5,545,1914,1837,16,298,849,1372,399,413,393,320,752,782,1169,1784,1699,1215,191,358,949,1051,1245,69,1666,1095,155,308,2208,611,1033,875,454,1172,1247,250,455,969,1484,428,59,1867,359,205,384,674,568,2570,1376,1001,1345,675,62,935,812,1119,130,2502,528,136,1075,1807,936,1515
|
0.4560011507642696,0.7559915142019157,1.7531245573462935,0.9478015835630615,-0.001127805810301048,-0.6725321288961622,1.9726052400824703,-0.9645715603540274,0.4560011507642696,0.09320779573109034,0.7976231963964028,0.35249256146592,0.4560011507642696,0.8936333486288025,-0.3271128392759249,-0.243884846085324,0.061932036437784624,-0.3945665116133365,-0.5492740993843713,1.014819277244463,2.0626573264796644,0.8114351982042777,-0.22738159228350283,-0.243884846085324,-0.017000063987738737,-0.514535240785251,-0.27703285170862874,1.5374592754176952,1.4884520937953238,-0.377629316099032,0.42661358757948437,1.4761368247888418,-0.243884846085324,0.7837786881907414,-0.7984810752691569,-0.377629316099032,0.17067086843316673,-0.31037139890127774,1.858096452664984,-0.3271128392759249,-0.04887504627384466,0.18604079096340007,-0.09701742595051951,0.24711890736266962,0.8800131050184969,1.8811746612706568,0.9207797152191141,-0.377629316099032,-0.7261736594651729,1.1985189212016558,-0.8717077957387307,0.1552603482535626,-0.21092513401942328,0.7699015142883784,0.24711890736266962,-0.9272458982666049,1.549648138953408,-1.0021412347204408,0.2013703373493341,-0.08092564237043719,0.014701291299391921,2.420435656490256,-0.7803189764195482,-0.17815150752877743,0.09320779573109034,0.09320779573109034,0.9881035286247505,0.7976231963964028,0.8114351982042777,0.17067086843316673,0.8800131050184969,0.7699015142883784,0.23190917857868676,0.09320779573109034,-0.3439027766845685,-0.8901609796463711,-0.27703285170862874,-1.0399582580540272,3.4883696583674233,-0.243884846085324,-0.5318785727630885,-0.19451519653859392,-1.0399582580540272,-0.9458784336451688,-0.12933524422973913,2.915245805395765,-0.17815150752877743,-0.14556179771058245,-0.4456774203599463,-0.08092564237043719,1.0014765288625636,1.8233108238857811,2.303532579472338,-0.5318785727630885,-0.4285902586631195,0.4998078409542412,2.637490586614291,-0.9272458982666049,0.5577119571515898,-0.22738159228350283,0.8663612864956289,0.09320779573109034,-0.3945665116133365,-0.14556179771058245,-0.462815185693309,0.3673920803157548,-0.514535240785251,1.338953943492325,0.2925118928589216,-0.0648782670729416,-0.8533136017184143,0.7140629338857863,1.1985189212016558,2.282030613119506,0.23190917857868676,-0.6370462182791121,-0.8533136017184143,-0.6547618971329058,-0.5842230489234069,0.09320779573109034,0.4413258066063131,-1.0971550435827746,0.07759089922445578,-0.7441656379825385,-0.4115533912456994,-0.6193847456466299,0.23190917857868676,-0.4800038669191164,-0.9086735477231258,-0.27703285170862874,-0.4285902586631195,-0.4285902586631195,-0.4972437792285436,0.2013703373493341,-0.9086735477231258,-0.7082376548394596,1.717718863168589,0.6292972508241202,-0.11315387381905866,-0.5492740993843713,0.10878295888408213,-0.462815185693309,-0.26043517265107846,-3.291501686426648,0.061932036437784624,1.463795947164361,1.6222608747574856,-5.875733142878054,0.030487470396744938,0.5720990698697436,-0.243884846085324,0.8663612864956289,-0.31037139890127774,0.2622891279230963,-0.017000063987738737,0.014701291299391921,0.6007678594820233,0.9612662003264605,-0.27703285170862874,-0.31037139890127774,3.0018786097104724,-0.21092513401942328,1.0810841689575286,1.658237345935038,0.8114351982042777,0.07759089922445578,0.3375549865593367,0.13980900706892938,-0.21092513401942328,-0.14556179771058245,0.9072221686279333,1.705870022831379,-0.6193847456466299,0.030487470396744938,2.7878758792557337,-0.5492740993843713,0.9207797152191141,0.6718330237408522,0.700019999999374,2.45192727608413,0.2013703373493341,2.441448397195739,0.6007678594820233,2.7381629713773825,0.2013703373493341,0.382253743928895,-0.6903572636353332,-0.5318785727630885,-0.6725321288961622,-0.377629316099032,0.10878295888408213,1.1855852561088989,0.5864509778300103,0.24711890736266962,0.7976231963964028,-0.21092513401942328,-0.3439027766845685,-0.032915728384741015,2.15137339820128,-1.0021412347204408,0.39707775152061925,0.41186430071853863,0.48524197874422104,2.1623710072700724,0.2013703373493341,3.2085718590601604,-0.001127805810301048,2.8371826720644844,-0.4972437792285436,1.94987853311504,0.7976231963964028,2.3463066784162883,-0.243884846085324,-0.19451519653859392,-0.4456774203599463,0.5577119571515898,0.3375549865593367,2.0849599804357837,0.852677740649789,0.35249256146592,0.6292972508241202,-0.0648782670729416,1.275532592400303,-0.5318785727630885,-0.7441656379825385,2.0065339889232616,2.3569527332268905,-0.22738159228350283,0.014701291299391921,-0.5318785727630885,0.1552603482535626,0.6435101106197167,0.13980900706892938,0.35249256146592,0.42661358757948437,-0.17815150752877743,0.48524197874422104,0.2774200528143013,-0.14556179771058245,0.7699015142883784,-0.1618337970909173,0.10878295888408213,1.9952458014491112,0.014701291299391921,1.211424359795403,0.6150498919054735,-0.6017771358819511,0.7699015142883784,1.6701813099617207,-0.21092513401942328,0.41186430071853863,-0.4456774203599463,4.00405433878558,0.5864509778300103,-0.4800038669191164,-0.4285902586631195,3.4352105279543297,1.1204890033550043,0.21665972726603153,-0.1618337970909173,0.8663612864956289,0.8252148517366122,0.8800131050184969,1.0414145845970093,0.30756485716682186,0.2774200528143013,-0.032915728384741015,-0.3945665116133365,-0.3439027766845685,-0.0648782670729416,1.5374592754176952,0.9478015835630615,0.12431661965225804,0.04623097246479662,-0.08092564237043719,2.4309512128450095,-0.3271128392759249,0.014701291299391921,1.8233108238857811,1.0942483489073807,-0.6725321288961622,0.4998078409542412,0.061932036437784624,0.2013703373493341,0.7559915142019157,-0.032915728384741015,-0.08092564237043719,1.3009827009421377,0.7559915142019157,0.10878295888408213,-0.22738159228350283,0.7976231963964028,2.5351071762344404,-0.4456774203599463,0.9478015835630615,1.463795947164361,0.8936333486288025,0.41186430071853863,0.5577119571515898,-1.174315546728808,-0.1618337970909173,0.09320779573109034,-0.14556179771058245,0.41186430071853863,2.4832547399290448,0.13980900706892938,0.24711890736266962,-0.001127805810301048,1.9612526973306057,-1.0210186165202892,0.6150498919054735,1.9270649969621256,0.030487470396744938,-0.4115533912456994,0.13980900706892938,-0.243884846085324
| 2,702
|
Ion transport
| 71
| 181
| 3.054693
| 0.002253
|
O15439,Q70HW3,Q8TB61,P07602,P78417,P21796,P13073,P33527,Q9H0H5,P53985,Q8NE01,Q9UBX3,Q9HD26,Q9BQT8,O75844,Q96PU5,Q8NEW0,Q96ES6,Q7KZN9,Q9C0H2,Q9UHG3,O15173,P45880,P30536,P05023,Q9UJS0,Q96QD8,Q9NZJ7,Q9BPX6,Q9Y6M7,Q9Y277,Q9H2D1,P08183,Q8NB49,O75964,Q9Y376,O75027,P16615,P31749,P20674,O43865,Q9HD20,P56134,O43707,Q9H2H9,P25705,P41440,O14936,Q8N4V1,O43772,O43808,P00403,P33176,Q9UDW1,P06576,Q13555,O43681,Q9BXP2,Q15907,Q9Y619,Q6P4A7,O00400,O95202,P28288,P12236,P51790,P24539,Q99808,Q13423,P14174,P04920
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
380,1,258,4,513,11,395,13,270,271,521,144,538,146,147,280,152,279,409,31,32,33,34,289,539,420,559,427,303,304,437,53,54,567,184,570,312,441,189,572,196,69,573,582,198,451,457,456,79,83,337,338,593,87,215,346,467,609,477,226,97,352,363,615,614,242,371,633,119,122,502
|
2352,2055,352,1099,1586,456,33,380,467,582,83,337,196,2057,312,2550,2531,1734,921,147,1637,1992,184,363,1151,785,338,665,818,1994,502,539,1252,860,957,215,1229,2327,4,1323,54,1057,1230,1175,889,1519,2062,978,614,395,2090,122,441,1874,2464,1022,572,1101,2406,2407,1233,11,941,371,451,2408,2233,615,2507,289,1381,189,2197,593,13,840,1614,1082,1876,457,1740,34,2434,1356,2508,1969,755,242,1463,271,787,1435,1821,573,904,721,841,1563,1158,865,513,1278,2115,2035,1436,1159,1360,757,1767,2220,119,346,1257,1028,2119,1335,1415,477,2556,1944,760,2657,642,1443,97,1,409,1110,2099,79,567,521,1660,152,258,1475,1621,2348,2427,279,1093,1503,280,559,669,2659,1031,633,303,146,609,31,270,1215,53,198,1629,896,69,538,427,2167,144,87,2600,32,1217,420,1073,1868,1376,2515,810,437,1805,570,1545,783,226,2549,304
|
-0.8349780072652183,-0.566722147958878,0.9478015835630615,-0.001127805810301048,-0.29367816551779385,0.7420485262435965,2.953902538225382,0.8936333486288025,0.7140629338857863,0.5288313967073893,2.3249577453845984,0.9747001337238531,1.4884520937953238,-0.566722147958878,1.0678905729851498,-1.1356055001499545,-1.0971550435827746,-0.377629316099032,0.13980900706892938,1.858096452664984,-0.3271128392759249,-0.5318785727630885,1.586065401491409,0.9207797152191141,-0.032915728384741015,0.2622891279230963,0.9747001337238531,0.41186430071853863,0.23190917857868676,-0.5318785727630885,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,0.10878295888408213,1.4017035243632918,-0.08092564237043719,-0.7984810752691569,4.00405433878558,-0.14556179771058245,2.5762697271805473,0.030487470396744938,-0.08092564237043719,-0.04887504627384466,0.17067086843316673,-0.26043517265107846,-0.566722147958878,0.09320779573109034,0.48524197874422104,0.8663612864956289,-0.5842230489234069,1.983936246561302,0.7699015142883784,-0.462815185693309,-0.9645715603540274,0.061932036437784624,0.5432894598416556,-0.001127805810301048,-0.8901609796463711,-0.8901609796463711,-0.08092564237043719,3.541068752096914,0.12431661965225804,0.9072221686279333,0.7559915142019157,-0.8901609796463711,-0.7082376548394596,0.48524197874422104,-1.0399582580540272,1.1596327314267856,-0.17815150752877743,1.549648138953408,-0.6725321288961622,0.5143375851029162,3.497184563628806,0.21665972726603153,-0.31037139890127774,0.014701291299391921,-0.462815185693309,0.7420485262435965,-0.377629316099032,2.953902538225382,-0.9272458982666049,-0.1618337970909173,-1.0399582580540272,-0.514535240785251,0.2925118928589216,1.3136668502909221,-0.22738159228350283,1.211424359795403,0.2622891279230963,-0.21092513401942328,-0.4285902586631195,0.5432894598416556,0.1552603482535626,0.3375549865593367,0.21665972726603153,-0.27703285170862874,-0.032915728384741015,0.2013703373493341,0.6292972508241202,-0.11315387381905866,-0.6017771358819511,-0.5492740993843713,-0.21092513401942328,-0.032915728384741015,-0.1618337970909173,0.2925118928589216,-0.3945665116133365,-0.6903572636353332,1.9952458014491112,0.9612662003264605,-0.09701742595051951,0.061932036437784624,-0.6017771358819511,-0.14556179771058245,-0.19451519653859392,0.700019999999374,-1.1356055001499545,-0.4972437792285436,0.2925118928589216,-1.6183674545716196,0.4560011507642696,-0.21092513401942328,2.217058138603211,4.343126506682812,0.8389623139505717,-0.001127805810301048,-0.5842230489234069,2.3463066784162883,0.5577119571515898,0.6150498919054735,-0.3271128392759249,1.8349285964616746,1.275532592400303,-0.22738159228350283,-0.31037139890127774,-0.8167006259673601,-0.9086735477231258,1.1985189212016558,0.014701291299391921,-0.243884846085324,1.1985189212016558,0.5720990698697436,0.41186430071853863,-1.6393962657387167,0.061932036437784624,0.4706398114973275,1.1073832487263275,1.8696467178692489,0.4998078409542412,2.9827338068802134,1.224301699534718,-0.0648782670729416,2.5967459172501477,1.4884520937953238,-0.31037139890127774,0.17067086843316673,2.4309512128450095,0.6007678594820233,0.7976231963964028,-0.6370462182791121,1.8811746612706568,2.303532579472338,-1.2722506277254433,2.9731386427052393,-0.0648782670729416,0.8114351982042777,0.030487470396744938,-0.4456774203599463,-0.1618337970909173,-1.0399582580540272,0.24711890736266962,0.7837786881907414,-0.4115533912456994,0.5577119571515898,-0.26043517265107846,0.2774200528143013,1.3766833583434828,-1.1163480492502467,1.1073832487263275
| 2,702
|
Abdominal pain
| 16
| 68
| 3.052811
| 0.002267
|
P07686,Q70HW3,Q8NFH4,O15460,P14174,P23786,P35637,P36551,Q8N1F7,P06280,Q13423,P42892,Q9NZ08,Q01844,P04062,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
160,1,291,195,122,105,203,269,238,112,119,55,250,253,188,29
|
456,195,582,2660,188,1198,112,1429,160,2150,1154,1519,2062,122,1127,1233,1431,1554,105,2298,840,1156,203,269,2433,1935,2629,55,879,924,1182,2175,984,658,2217,2345,1277,565,253,1159,566,749,1361,119,29,296,926,789,991,1209,2398,2267,1108,1,238,727,291,928,1693,705,1000,1140,250,2470,674,771,528,1703
|
0.7420485262435965,1.500741864308918,0.5288313967073893,-1.6816883017518833,1.549648138953408,-0.0648782670729416,2.040271181152975,-0.21092513401942328,1.7531245573462935,-0.6370462182791121,-0.032915728384741015,-0.26043517265107846,-0.566722147958878,1.983936246561302,-0.017000063987738737,-0.08092564237043719,-0.21092513401942328,-0.27703285170862874,2.096080199744481,-0.7622139544215649,0.21665972726603153,-0.032915728384741015,1.463795947164361,1.224301699534718,-0.9272458982666049,-0.4972437792285436,-1.4325193129919627,2.5660054539144865,0.18604079096340007,0.13980900706892938,-0.04887504627384466,-0.6547618971329058,0.09320779573109034,0.42661358757948437,-0.6903572636353332,-0.8167006259673601,-0.11315387381905866,0.5577119571515898,1.2882713222080582,-0.032915728384741015,0.5577119571515898,0.30756485716682186,-0.1618337970909173,1.9952458014491112,3.0018786097104724,1.1335657467919271,0.13980900706892938,0.2622891279230963,0.09320779573109034,-0.0648782670729416,-0.8717077957387307,-0.7261736594651729,-0.001127805810301048,4.343126506682812,1.3263238911225568,0.3375549865593367,1.1596327314267856,0.13980900706892938,-0.3439027766845685,0.3673920803157548,0.09320779573109034,-0.017000063987738737,1.3009827009421377,-0.9645715603540274,0.41186430071853863,0.2925118928589216,0.6150498919054735,-0.3439027766845685
| 2,702
|
primary active transporter
| 11
| 24
| 3.03078
| 0.002439
|
Q9NS69,Q6P4A7,P05023,Q8N4H5,O75381,O60888,Q15388,Q9Y5J7,P12270,P16615,Q9BUN8
|
Functions
|
Panther Protein class
|
panther_protein_class
|
0,97,539,72,301,174,366,317,370,441,413
|
174,301,1225,785,539,1252,370,441,1022,941,1821,1278,366,1415,963,97,72,567,1503,413,1629,1374,0,317
|
1.658237345935038,1.1073832487263275,-0.08092564237043719,0.2622891279230963,0.5864509778300103,-0.09701742595051951,0.9072221686279333,0.7699015142883784,0.061932036437784624,0.12431661965225804,-0.4285902586631195,-0.11315387381905866,0.9207797152191141,-0.19451519653859392,0.10878295888408213,2.217058138603211,2.420435656490256,0.5577119571515898,-0.243884846085324,0.8252148517366122,-0.31037139890127774,-0.1618337970909173,4.48719359410752,1.0546674241385827
| 2,702
|
Protein targeting to mitochondrion
| 16
| 39
| 3.022342
| 0.002508
|
Q9NS69,P30536,Q99595,Q5JRX3,Q8N4H5,O95831,P51572,O14737,Q10713,Q53H12,Q15388,Q9Y5J9,Q9P0J0,O14925,Q9Y5J7,P55786
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,289,2,295,72,9,469,265,397,237,366,400,375,344,317,28
|
1219,265,344,549,1734,1225,1296,9,785,1551,2133,2560,289,2372,1327,469,28,2394,397,366,1043,237,295,2164,72,484,805,2,764,634,1139,1374,0,375,2364,569,663,317,400
|
-0.08092564237043719,1.237151067189716,0.9612662003264605,0.5720990698697436,-0.377629316099032,-0.08092564237043719,-0.12933524422973913,3.601980510099323,0.2622891279230963,-0.27703285170862874,-0.6193847456466299,-1.1549278473496636,1.1596327314267856,-0.8533136017184143,-0.14556179771058245,0.7140629338857863,3.0018786097104724,-0.8717077957387307,0.8663612864956289,0.9207797152191141,0.04623097246479662,1.3263238911225568,1.1466136121023172,-0.6370462182791121,2.420435656490256,0.6859434192423728,0.24711890736266962,4.084595663215114,0.2925118928589216,0.4706398114973275,-0.017000063987738737,-0.1618337970909173,4.48719359410752,0.9072221686279333,-0.8349780072652183,0.5577119571515898,0.42661358757948437,1.0546674241385827,0.8663612864956289
| 2,702
|
Organophosphate ester transport
| 14
| 26
| 3.002866
| 0.002674
|
O15439,P61916,Q8TB61,Q8WTV0,O00400,P41440,P33527,P12236,Q9H2D1,P08183,Q8NB49,O43808,Q99808,Q14108
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
380,248,258,324,352,457,13,614,53,54,567,337,633,29
|
352,380,337,860,54,978,614,1555,1353,13,457,1765,248,757,29,760,642,567,258,1475,324,633,1784,53,896,1484
|
0.9478015835630615,0.8936333486288025,0.9747001337238531,0.2013703373493341,2.5762697271805473,0.09320779573109034,0.48524197874422104,-0.27703285170862874,-0.1618337970909173,3.497184563628806,0.7420485262435965,-0.3945665116133365,1.3009827009421377,0.2925118928589216,3.0018786097104724,0.2925118928589216,0.4560011507642696,0.5577119571515898,1.275532592400303,-0.22738159228350283,1.0281319155612654,0.4706398114973275,-0.3945665116133365,2.5967459172501477,0.17067086843316673,-0.22738159228350283
| 2,702
|
Mitochondrial protein import
| 20
| 34
| 3.000982
| 0.002691
|
Q9NS69,Q99595,P21796,Q10713,Q9Y5J9,Q13505,Q9UJS0,Q5JRX3,O43615,Q9Y5J7,P25705,Q8N4H5,O95169,O14925,P06576,Q9NX63,Q15388,P12236,O75431,Q9BVV7
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,2,11,397,400,156,420,295,549,317,451,72,592,344,215,350,366,614,499,634
|
344,549,2601,499,1734,921,1225,592,785,215,1230,2133,978,614,11,451,2318,397,156,366,1043,295,72,2,2414,634,1374,0,350,420,1758,663,317,400
|
0.9612662003264605,0.5720990698697436,-1.2920402919692853,0.6576886443457405,-0.377629316099032,0.13980900706892938,-0.08092564237043719,0.5143375851029162,0.2622891279230963,1.4017035243632918,-0.08092564237043719,-0.6193847456466299,0.09320779573109034,0.48524197874422104,3.541068752096914,0.7559915142019157,-0.7803189764195482,0.8663612864956289,1.7883210270224281,0.9207797152191141,0.04623097246479662,1.1466136121023172,2.420435656490256,4.084595663215114,-0.8901609796463711,0.4706398114973275,-0.1618337970909173,4.48719359410752,0.9612662003264605,0.8114351982042777,-0.377629316099032,0.42661358757948437,1.0546674241385827,0.8663612864956289
| 2,702
|
Inorganic anion transport
| 14
| 27
| 2.980779
| 0.002875
|
O15439,Q9UHG3,P30536,P45880,P21796,P33527,Q9H0H5,Q9UBX3,Q9Y6M7,P51790,Q9Y277,P08183,O43681,Q9C0H2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
380,32,289,34,11,13,270,144,304,242,437,54,467,31
|
2055,380,467,502,54,11,289,13,34,242,1463,787,2115,1159,760,2657,1475,669,609,31,270,144,32,437,1805,2549,304
|
-0.566722147958878,0.8936333486288025,0.7140629338857863,0.6435101106197167,2.5762697271805473,3.541068752096914,1.1596327314267856,3.497184563628806,2.953902538225382,1.3136668502909221,-0.22738159228350283,0.2622891279230963,-0.6017771358819511,-0.032915728384741015,0.2925118928589216,-1.6183674545716196,-0.22738159228350283,0.41186430071853863,0.4998078409542412,2.9827338068802134,1.224301699534718,1.8811746612706568,2.9731386427052393,0.7837786881907414,-0.4115533912456994,-1.1163480492502467,1.1073832487263275
| 2,702
|
Mitochondrion organization
| 41
| 157
| 2.980026
| 0.002882
|
Q9NS69,Q99595,Q9BUR5,O95831,Q8N163,P21796,O14737,Q10713,Q9Y2R0,O43676,Q13505,P55786,P30536,P45880,Q5JRX3,O75153,Q69YU5,O75832,Q9Y3B8,Q9NUQ9,P04062,P31749,Q9Y5J7,O60313,Q8N4H5,Q9UDX5,Q96A26,Q7L592,Q15070,O14925,Q9NX63,P14406,Q6DKK2,Q53H12,Q15388,O95202,P02545,Q9P0J0,Q8IWA4,O96000,Q7Z406
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,2,393,9,137,11,265,397,14,20,156,28,289,34,295,44,45,302,58,316,188,189,317,326,72,200,80,209,85,344,350,96,100,237,366,363,241,375,373,369,383
|
1219,2148,2687,1099,265,344,549,20,1895,326,44,2634,2531,1608,499,1734,1322,302,529,1225,1517,731,592,363,2088,1296,9,369,785,241,665,188,2192,1198,860,1551,1710,1995,2133,862,978,96,1199,2560,11,2408,2418,2277,2507,1004,289,189,2372,1818,2392,1523,2318,2300,1740,34,1592,1327,1560,983,720,469,1680,1681,28,1006,2394,2320,1467,908,397,156,1184,85,893,366,683,2556,478,2290,1944,555,1043,237,295,726,45,100,1089,2639,209,383,2164,1472,373,995,1981,2166,137,72,1500,1660,484,2292,1621,80,930,780,791,805,2659,460,2,1031,2609,764,806,1838,765,1191,393,634,1865,1139,968,1373,1374,586,1604,0,1013,316,808,580,350,1053,375,2364,200,1117,1844,1073,1758,14,886,569,58,783,663,317,400,509,953
|
-0.08092564237043719,-0.6370462182791121,-2.830790652033712,-0.001127805810301048,1.237151067189716,0.9612662003264605,0.5720990698697436,3.1993280187186217,-0.4800038669191164,1.014819277244463,2.777966008575487,-1.4732988595445302,-1.0971550435827746,-0.31037139890127774,0.6576886443457405,-0.377629316099032,-0.14556179771058245,1.1073832487263275,0.6007678594820233,-0.08092564237043719,-0.26043517265107846,0.32257915315367963,0.5143375851029162,0.9207797152191141,-0.5842230489234069,-0.12933524422973913,3.601980510099323,0.9072221686279333,0.2622891279230963,1.3136668502909221,0.41186430071853863,1.549648138953408,-0.6725321288961622,-0.0648782670729416,0.2013703373493341,-0.27703285170862874,-0.36074150382824394,-0.5318785727630885,-0.6193847456466299,0.2013703373493341,0.09320779573109034,2.217058138603211,-0.0648782670729416,-1.1549278473496636,3.541068752096914,-0.8901609796463711,-0.9086735477231258,-0.7441656379825385,-1.0399582580540272,0.07759089922445578,1.1596327314267856,1.549648138953408,-0.8533136017184143,-0.4285902586631195,-0.8717077957387307,-0.26043517265107846,-0.7803189764195482,-0.7622139544215649,-0.377629316099032,2.953902538225382,-0.29367816551779385,-0.14556179771058245,-0.27703285170862874,0.09320779573109034,0.3375549865593367,0.7140629338857863,-0.3439027766845685,-0.3439027766845685,3.0018786097104724,0.07759089922445578,-0.8717077957387307,-0.7803189764195482,-0.22738159228350283,0.1552603482535626,0.8663612864956289,1.7883210270224281,-0.04887504627384466,2.314254726861213,0.17067086843316673,0.9207797152191141,0.39707775152061925,-1.1356055001499545,0.700019999999374,-0.7441656379825385,-0.4972437792285436,0.5720990698697436,0.04623097246479662,1.3263238911225568,1.1466136121023172,0.3375549865593367,2.748138375991167,2.1733484536781895,0.014701291299391921,-1.4937984028764713,1.4390369219353498,0.8936333486288025,-0.6370462182791121,-0.22738159228350283,0.9072221686279333,0.09320779573109034,-0.514535240785251,-0.6370462182791121,1.9156254520629414,2.420435656490256,-0.243884846085324,-0.3271128392759249,0.6859434192423728,-0.7441656379825385,-0.31037139890127774,2.3463066784162883,0.13980900706892938,0.2774200528143013,0.2622891279230963,0.24711890736266962,-1.6393962657387167,0.7420485262435965,4.084595663215114,0.061932036437784624,-1.311898640240956,0.2925118928589216,0.24711890736266962,-0.4285902586631195,0.2925118928589216,-0.04887504627384466,0.8800131050184969,0.4706398114973275,-0.4456774203599463,-0.017000063987738737,0.10878295888408213,-0.1618337970909173,-0.1618337970909173,0.5288313967073893,-0.29367816551779385,4.48719359410752,0.07759089922445578,1.0546674241385827,0.24711890736266962,0.5432894598416556,0.9612662003264605,0.04623097246479662,0.9072221686279333,-0.8349780072652183,1.4884520937953238,-0.001127805810301048,-0.4285902586631195,0.030487470396744938,-0.377629316099032,3.497184563628806,0.18604079096340007,0.5577119571515898,2.55572364594437,0.2774200528143013,0.42661358757948437,1.0546674241385827,0.8663612864956289,0.6435101106197167,0.12431661965225804
| 2,702
|
Receptor
| 11
| 25
| 2.959236
| 0.003084
|
P11717,Q8WTV0,O75381,A6NIH7,Q9NR77,Q9UQB8,Q13432,Q567V2,Q13641,Q14108,Q9BUN8
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
417,324,301,46,78,222,214,149,254,29,413
|
46,1077,1959,301,2212,1961,957,417,1676,431,1715,214,254,29,149,963,324,761,413,1700,78,1248,2249,222,1377
|
2.7381629713773825,0.014701291299391921,-0.514535240785251,1.1073832487263275,-0.6903572636353332,-0.514535240785251,0.10878295888408213,0.8114351982042777,-0.3439027766845685,0.7837786881907414,-0.36074150382824394,1.4141741225146764,1.2882713222080582,3.0018786097104724,1.858096452664984,0.10878295888408213,1.0281319155612654,0.2925118928589216,0.8252148517366122,-0.3439027766845685,2.3569527332268905,-0.08092564237043719,-0.7082376548394596,1.3892066414158972,-0.1618337970909173
| 2,702
|
transporter
| 13
| 56
| 2.959144
| 0.003085
|
Q9Y619,Q99595,P37198,Q9NR77,P53985,Q8N1F7,O43772,Q567V2,Q9H2D1,Q9H2V7,Q15070,P52292,Q9HD45
|
Functions
|
Panther Protein class
|
panther_protein_class
|
226,2,133,78,271,238,83,149,53,153,85,90,285
|
664,2310,814,2516,1077,1002,549,467,83,2087,1610,1078,733,133,457,1765,1713,90,1235,1526,271,787,1274,985,658,1563,566,1010,85,149,2657,557,238,291,1091,492,895,434,804,847,707,2,848,633,1477,1448,53,153,1700,285,78,2402,2485,1073,1634,226
|
0.41186430071853863,-0.7803189764195482,0.23190917857868676,-1.0589605873257606,0.014701291299391921,0.07759089922445578,0.5720990698697436,0.7140629338857863,2.3249577453845984,-0.5842230489234069,-0.31037139890127774,0.014701291299391921,0.32257915315367963,1.9384826617323367,0.7420485262435965,-0.3945665116133365,-0.36074150382824394,2.282030613119506,-0.08092564237043719,-0.26043517265107846,1.211424359795403,0.2622891279230963,-0.11315387381905866,0.09320779573109034,0.42661358757948437,-0.27703285170862874,0.5577119571515898,0.07759089922445578,2.314254726861213,1.858096452664984,-1.6183674545716196,0.5720990698697436,1.3263238911225568,1.1596327314267856,0.014701291299391921,0.6718330237408522,0.17067086843316673,0.7837786881907414,0.24711890736266962,0.21665972726603153,0.3673920803157548,4.084595663215114,0.21665972726603153,0.4706398114973275,-0.22738159228350283,-0.21092513401942328,2.5967459172501477,1.8349285964616746,-0.3439027766845685,1.1855852561088989,2.3569527332268905,-0.8717077957387307,-0.983325689072196,0.030487470396744938,-0.31037139890127774,1.3766833583434828
| 2,702
|
Hydrolase activity acting on glycosyl bonds
| 12
| 25
| 2.958722
| 0.003089
|
P07686,P17900,O60502,O75503,P06865,P06280,Q9BTY2,P54802,P10253,P04062,P16278,P08236
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
160,162,74,206,92,112,307,50,220,188,93,158
|
2672,1147,74,206,188,439,112,92,160,158,220,2355,93,162,1301,2408,878,1061,50,605,1617,1718,478,307,333
|
-1.9200896765948166,-0.032915728384741015,2.378188367259261,1.4514293500729303,1.549648138953408,0.7699015142883784,2.040271181152975,2.249632405350508,1.7531245573462935,1.7648798340833782,1.3892066414158972,-0.8349780072652183,2.2387939765464413,1.7295441678744543,-0.12933524422973913,-0.8901609796463711,0.18604079096340007,0.030487470396744938,2.6577600342457113,0.4998078409542412,-0.31037139890127774,-0.36074150382824394,0.700019999999374,1.0942483489073807,1.0014765288625636
| 2,702
|
RNA recognition motif domain [IPR000504]
| 48
| 110
| 2.955587
| 0.003121
|
P51991,P23588,Q8WUA2,P52597,Q99729,Q9UHX1,Q9P2N5,Q15233,Q86U42,P26368,Q9P2K5,Q12849,P31942,Q01085,Q8N684,Q13595,Q13242,Q86V81,Q92804,P78332,P98175,P07910,Q07955,P35637,Q14103,P23246,Q96PK6,Q15287,P38159,Q8WXF1,P62995,Q16629,Q13151,Q8IXT5,O43390,P52272,P98179,O60506,P22626,Q9BWF3,Q9Y6M1,O75494,Q13247,P43243,P31943,Q01844,P55795,O14979
|
Sequence
|
InterPro Domain
|
interpro_domain
|
390,510,264,266,268,141,524,403,412,666,429,681,168,552,696,693,318,704,194,702,322,450,453,203,464,335,336,597,212,473,339,607,723,737,219,476,224,227,354,493,498,361,617,616,247,253,382,251
|
1424,971,251,1220,1266,219,1872,227,361,2059,1709,450,1153,1640,1518,922,773,786,1457,1231,354,335,510,666,1432,1903,168,247,1645,203,212,2374,616,1524,390,476,266,1040,382,2216,339,702,907,322,224,552,253,2678,453,1083,681,1203,723,318,962,617,2038,1042,693,464,1363,1529,2004,2122,991,403,597,1106,1208,944,607,1770,1306,1418,412,704,737,1310,1692,696,1090,264,2540,473,194,1066,1167,966,336,915,2385,268,493,740,1783,1865,1483,1668,2102,851,429,524,141,1514,884,1344,1633,1173,1704,498
|
-0.21092513401942328,0.09320779573109034,1.2882713222080582,-0.08092564237043719,-0.11315387381905866,1.3892066414158972,-0.462815185693309,1.364133559046907,0.9343061375179438,-0.566722147958878,-0.36074150382824394,0.7559915142019157,-0.032915728384741015,-0.3271128392759249,-0.26043517265107846,0.13980900706892938,0.2774200528143013,0.2622891279230963,-0.22738159228350283,-0.08092564237043719,0.9478015835630615,0.9881035286247505,0.6292972508241202,0.41186430071853863,-0.21092513401942328,-0.4800038669191164,1.6701813099617207,1.3009827009421377,-0.3271128392759249,1.463795947164361,1.4141741225146764,-0.8533136017184143,0.48524197874422104,-0.26043517265107846,0.8800131050184969,0.700019999999374,1.237151067189716,0.04623097246479662,0.8936333486288025,-0.6903572636353332,0.9747001337238531,0.3673920803157548,0.1552603482535626,1.0281319155612654,1.3766833583434828,0.5720990698697436,1.2882713222080582,-2.0093246694096405,0.7559915142019157,0.014701291299391921,0.39707775152061925,-0.0648782670729416,0.3375549865593367,1.0414145845970093,0.10878295888408213,0.48524197874422104,-0.5492740993843713,0.04623097246479662,0.382253743928895,0.7280723875131836,-0.1618337970909173,-0.26043517265107846,-0.5318785727630885,-0.6017771358819511,0.09320779573109034,0.852677740649789,0.5143375851029162,-0.001127805810301048,-0.0648782670729416,0.12431661965225804,0.4998078409542412,-0.3945665116133365,-0.12933524422973913,-0.19451519653859392,0.8252148517366122,0.3673920803157548,0.32257915315367963,-0.12933524422973913,-0.3439027766845685,0.382253743928895,0.014701291299391921,1.249972588664049,-1.0971550435827746,0.7140629338857863,1.5130062457371627,0.030487470396744938,-0.032915728384741015,0.10878295888408213,0.9881035286247505,0.1552603482535626,-0.8533136017184143,1.237151067189716,0.6718330237408522,0.32257915315367963,-0.3945665116133365,-0.4456774203599463,-0.22738159228350283,-0.3271128392759249,-0.5842230489234069,0.21665972726603153,0.7976231963964028,0.6150498919054735,1.8926803722806396,-0.243884846085324,0.18604079096340007,-0.14556179771058245,-0.31037139890127774,-0.032915728384741015,-0.3439027766845685,0.6718330237408522
| 2,702
|
Hepatic failure
| 12
| 40
| 2.95004
| 0.003177
|
O15118,Q9Y619,O15460,P38571,P22830,P23786,O75381,O43772,P09622,Q13510,P04062,P40855
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
63,226,195,389,7,105,301,83,25,26,188,288
|
63,195,83,1811,301,627,2024,188,1429,1230,25,1081,7,105,615,2651,389,288,1739,2452,924,983,2377,1467,397,749,26,994,1470,542,1690,1240,1168,1373,1097,686,1669,708,1634,226
|
2.472830381816948,1.500741864308918,2.3249577453845984,-0.4285902586631195,1.1073832487263275,0.4706398114973275,-0.5492740993843713,1.549648138953408,-0.21092513401942328,-0.08092564237043719,3.0399875010519266,0.014701291299391921,3.7135134684721347,2.096080199744481,0.48524197874422104,-1.5765412690495015,0.8800131050184969,1.1726232359899564,-0.377629316099032,-0.9458784336451688,0.13980900706892938,0.09320779573109034,-0.8533136017184143,-0.22738159228350283,0.8663612864956289,0.30756485716682186,3.0114283478612625,0.09320779573109034,-0.22738159228350283,0.5864509778300103,-0.3439027766845685,-0.08092564237043719,-0.032915728384741015,-0.1618337970909173,0.014701291299391921,0.39707775152061925,-0.3271128392759249,0.3673920803157548,-0.31037139890127774,1.3766833583434828
| 2,702
|
Sterol binding
| 6
| 15
| 2.941901
| 0.003262
|
O15118,P30536,P45880,P21796,P61916,Q14108
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
63,289,34,11,248,29
|
63,887,1250,1323,11,1555,1353,289,34,248,29,2047,1698,1784,358
|
2.472830381816948,0.17067086843316673,-0.09701742595051951,-0.14556179771058245,3.541068752096914,-0.27703285170862874,-0.1618337970909173,1.1596327314267856,2.953902538225382,1.3009827009421377,3.0018786097104724,-0.5492740993843713,-0.3439027766845685,-0.3945665116133365,0.9478015835630615
| 2,702
|
Calcium-binding protein
| 6
| 14
| 2.930388
| 0.003385
|
P80303,Q8N163,Q02818,P43307,Q14257,O43852
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
135,137,236,51,52,190
|
190,1998,732,51,905,986,135,236,52,694,1210,137,303,570
|
1.5374592754176952,-0.5318785727630885,0.32257915315367963,2.637490586614291,0.1552603482535626,0.09320779573109034,1.9270649969621256,1.3263238911225568,2.6273302312130475,0.382253743928895,-0.0648782670729416,1.9156254520629414,1.1073832487263275,0.5577119571515898
| 2,702
|
Ascites
| 7
| 23
| 2.925223
| 0.003442
|
O15118,Q14739,P61916,Q13510,P04062,Q14108,P08236
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
63,175,248,26,188,29,158
|
63,2474,1897,1251,188,158,1154,1127,1081,389,1593,248,2238,1466,1467,253,749,26,29,175,1209,897,1634
|
2.472830381816948,-0.983325689072196,-0.4800038669191164,-0.09701742595051951,1.549648138953408,1.7648798340833782,-0.032915728384741015,-0.017000063987738737,0.014701291299391921,0.8800131050184969,-0.29367816551779385,1.3009827009421377,-0.7082376548394596,-0.22738159228350283,-0.22738159228350283,1.2882713222080582,0.30756485716682186,3.0114283478612625,3.0018786097104724,1.658237345935038,-0.0648782670729416,0.17067086843316673,-0.31037139890127774
| 2,702
|
Ion channel transport
| 11
| 27
| 2.913662
| 0.003572
|
P05023,Q9HD20,Q9Y5K8,Q9Y487,Q15904,Q93050,Q96PU5,P51790,Q13555,P16615,Q9C0H2
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
539,69,561,41,488,82,280,242,346,441,31
|
539,1252,441,1022,1101,2406,941,1381,1082,1876,242,1463,1821,841,1278,1616,346,488,760,567,82,280,31,69,1217,41,561
|
0.5864509778300103,-0.09701742595051951,0.7699015142883784,0.061932036437784624,-0.001127805810301048,-0.8901609796463711,0.12431661965225804,-0.17815150752877743,0.014701291299391921,-0.462815185693309,1.3136668502909221,-0.22738159228350283,-0.4285902586631195,0.21665972726603153,-0.11315387381905866,-0.31037139890127774,0.9612662003264605,0.6718330237408522,0.2925118928589216,0.5577119571515898,2.3356417057869807,1.1985189212016558,2.9827338068802134,2.4309512128450095,-0.0648782670729416,2.8371826720644844,0.5720990698697436
| 2,702
|
Cholesterol binding
| 6
| 12
| 2.911152
| 0.003601
|
O15118,P30536,P45880,P21796,P61916,Q14108
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
63,289,34,11,248,29
|
63,887,1250,1323,11,1353,289,34,248,29,1784,358
|
2.472830381816948,0.17067086843316673,-0.09701742595051951,-0.14556179771058245,3.541068752096914,-0.1618337970909173,1.1596327314267856,2.953902538225382,1.3009827009421377,3.0018786097104724,-0.3945665116133365,0.9478015835630615
| 2,702
|
Proton transmembrane transporter activity
| 17
| 34
| 2.90714
| 0.003648
|
P20674,P25705,P06576,Q9Y5K8,O00400,Q9Y487,P13073,O95202,Q93050,P51790,Q96ES6,P24539,P00403,Q13423,O75964,Q7KZN9,Q9UDW1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
572,451,215,561,352,41,395,363,82,242,279,371,338,119,184,409,87
|
352,1992,184,363,338,860,215,1230,1175,978,395,572,1101,2406,371,451,2197,1614,1082,1876,2508,242,573,904,841,2115,119,409,82,279,87,1217,41,561
|
0.9478015835630615,-0.5318785727630885,1.586065401491409,0.9207797152191141,0.9747001337238531,0.2013703373493341,1.4017035243632918,-0.08092564237043719,-0.04887504627384466,0.09320779573109034,0.8663612864956289,0.5432894598416556,-0.001127805810301048,-0.8901609796463711,0.9072221686279333,0.7559915142019157,-0.6725321288961622,-0.31037139890127774,0.014701291299391921,-0.462815185693309,-1.0399582580540272,1.3136668502909221,0.5432894598416556,0.1552603482535626,0.21665972726603153,-0.6017771358819511,1.9952458014491112,0.8389623139505717,2.3356417057869807,1.1985189212016558,2.303532579472338,-0.0648782670729416,2.8371826720644844,0.5720990698697436
| 2,702
|
Tetrapyrrole binding
| 7
| 15
| 2.905624
| 0.003665
|
Q16850,O15173,P30519,Q8WUJ1,O43169,P09601,O00264
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
65,33,35,68,36,334,159
|
159,33,36,1230,334,1554,35,65,652,409,68,1371,632,635,1423
|
1.7531245573462935,2.953902538225382,2.886090180376803,-0.08092564237043719,0.9881035286247505,-0.27703285170862874,2.915245805395765,2.45192727608413,0.4413258066063131,0.8389623139505717,2.4309512128450095,-0.1618337970909173,0.4706398114973275,0.4706398114973275,-0.19451519653859392
| 2,702
|
Steroid metabolic process
| 21
| 58
| 2.901539
| 0.003713
|
P38571,P16435,P48449,Q9BQE5,O95470,Q13510,P37268,P30536,Q15392,Q14739,Q14534,P04062,O15118,Q16850,Q8WTV0,P38435,Q9UBM7,Q9H4L5,Q15800,P61916,Q99538
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
389,388,396,16,275,26,154,289,166,175,311,188,63,65,324,86,359,358,367,248,121
|
63,887,1174,1250,275,2431,188,539,1736,2062,678,2602,388,1555,1353,2341,2450,615,289,154,86,389,2300,396,1359,2281,1593,2177,248,1564,2438,1360,26,2555,311,175,2382,166,1469,725,2043,367,65,535,1281,424,324,2140,2047,121,2609,16,1094,358,359,1290,837,1955
|
2.472830381816948,0.17067086843316673,-0.04887504627384466,-0.09701742595051951,1.1985189212016558,-0.9272458982666049,1.549648138953408,0.5864509778300103,-0.377629316099032,-0.566722147958878,0.39707775152061925,-1.2920402919692853,0.8800131050184969,-0.27703285170862874,-0.1618337970909173,-0.8167006259673601,-0.9458784336451688,0.48524197874422104,1.1596327314267856,1.8233108238857811,2.303532579472338,0.8800131050184969,-0.7622139544215649,0.8663612864956289,-0.1618337970909173,-0.7441656379825385,-0.29367816551779385,-0.6547618971329058,1.3009827009421377,-0.27703285170862874,-0.9272458982666049,-0.1618337970909173,3.0114283478612625,-1.1356055001499545,1.0810841689575286,1.658237345935038,-0.8533136017184143,1.705870022831379,-0.22738159228350283,0.3375549865593367,-0.5492740993843713,0.9207797152191141,2.45192727608413,0.6007678594820233,-0.11315387381905866,0.7976231963964028,1.0281319155612654,-0.6193847456466299,-0.5492740993843713,1.9952458014491112,-1.311898640240956,3.4352105279543297,0.014701291299391921,0.9478015835630615,0.9478015835630615,-0.11315387381905866,0.23190917857868676,-0.4972437792285436
| 2,702
|
Molecular transducer activity
| 11
| 29
| 2.900676
| 0.003724
|
O15118,O15173,P30536,P11717,Q5KU26,Q99720,Q9P2E9,Q8WTV0,Q15629,Q14108,Q9BUN8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
63,33,289,417,163,5,428,324,43,29,413
|
1404,815,63,33,1636,957,1900,417,1676,289,1935,1182,2074,757,1715,1161,29,43,1415,483,163,1691,324,2348,5,413,428,674,568
|
-0.19451519653859392,0.23190917857868676,2.472830381816948,2.953902538225382,-0.3271128392759249,0.10878295888408213,-0.4800038669191164,0.8114351982042777,-0.3439027766845685,1.1596327314267856,-0.4972437792285436,-0.04887504627384466,-0.566722147958878,0.2925118928589216,-0.36074150382824394,-0.032915728384741015,3.0018786097104724,2.7878758792557337,-0.19451519653859392,0.6859434192423728,1.7295441678744543,-0.3439027766845685,1.0281319155612654,-0.8167006259673601,4.00405433878558,0.8252148517366122,0.7976231963964028,0.41186430071853863,0.5577119571515898
| 2,702
|
Hydrolase activity hydrolyzing o glycosyl compounds
| 13
| 18
| 2.897878
| 0.003757
|
P07686,P17900,O60502,Q9NUJ1,P06280,P54802,P04062,P10253,Q9BTY2,P04066,P06865,P16278,P08236
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
160,162,74,333,112,50,188,220,307,439,92,93,158
|
2672,74,188,439,112,92,160,158,220,93,162,1061,50,1617,1718,478,307,333
|
-1.9200896765948166,2.378188367259261,1.549648138953408,0.7699015142883784,2.040271181152975,2.249632405350508,1.7531245573462935,1.7648798340833782,1.3892066414158972,2.2387939765464413,1.7295441678744543,0.030487470396744938,2.6577600342457113,-0.31037139890127774,-0.36074150382824394,0.700019999999374,1.0942483489073807,1.0014765288625636
| 2,702
|
Organelle inner membrane
| 72
| 205
| 2.895255
| 0.003789
|
Q70HW3,Q99595,Q03252,Q99720,Q9BUR5,P22830,O95831,P13073,P36551,Q9Y2R0,Q10713,Q9UBX3,Q6PI78,Q9BQT8,O75844,O43676,Q567V2,Q9Y5J9,P61970,P34897,P22695,O75880,Q9H2V7,Q13505,Q8IXM6,Q7KZN9,Q9UJS0,Q9UH99,Q16891,O43615,Q69YU5,Q14739,Q9BPX6,Q9H1E5,Q9H2D1,P20700,O75964,O75027,Q9Y5J7,Q9Y2U8,Q9NVI7,Q9H2W6,O95674,P20674,P25705,O60313,Q9UDX5,O43772,Q15070,P00403,P62995,Q9UDW1,P06576,O14949,O14925,Q9NX63,P14406,Q6P4A7,Q9Y619,Q6DKK2,P23786,P50402,Q53H12,Q9Y6C9,O95202,Q16540,O75431,Q9P0J0,P24539,Q13423,O96000,P82933
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,2,391,5,393,7,9,395,269,14,397,144,398,146,147,20,149,400,23,531,530,529,153,156,404,409,420,560,555,549,45,175,303,177,53,309,184,312,317,581,580,579,438,572,451,326,200,83,85,338,339,87,215,218,344,350,96,97,226,100,105,233,237,509,363,489,499,375,371,119,369,252
|
2687,1586,344,218,549,20,1895,83,326,312,2531,1608,499,1734,1322,1020,1149,921,147,529,1992,184,1406,1174,1517,731,592,1787,363,2088,1151,438,9,369,785,338,860,215,2488,1230,2276,1710,2370,1175,2133,978,614,2170,395,96,1430,1199,819,2465,572,309,1431,2341,530,7,1301,105,371,451,2418,2298,2197,531,1818,1614,269,2318,1739,1712,616,1025,2508,1359,1969,2642,233,2032,1680,1742,1411,2377,573,904,23,339,1466,942,1132,2219,1527,2623,252,2115,1159,391,397,1687,842,119,156,2182,175,85,845,489,2290,1944,555,1043,237,149,651,2538,726,45,100,642,97,398,1089,2077,1,409,2139,1165,1472,404,1474,1137,1660,1621,1311,1622,1263,2612,2427,778,1189,1503,791,2,1031,5,303,146,1505,1538,1838,765,393,634,2334,1916,2399,1506,1839,177,53,153,579,968,1373,1629,2101,1509,1374,896,2363,2559,1603,1579,808,580,350,2130,1289,1053,375,144,87,200,1117,560,420,1073,1758,1632,14,708,581,1845,1486,1846,783,663,317,400,226,509,953
|
-2.830790652033712,-0.29367816551779385,0.9612662003264605,1.3892066414158972,0.5720990698697436,3.1993280187186217,-0.4800038669191164,2.3249577453845984,1.014819277244463,1.0678905729851498,-1.0971550435827746,-0.31037139890127774,0.6576886443457405,-0.377629316099032,-0.14556179771058245,0.061932036437784624,-0.032915728384741015,0.13980900706892938,1.858096452664984,0.6007678594820233,-0.5318785727630885,1.586065401491409,-0.19451519653859392,-0.04887504627384466,-0.26043517265107846,0.32257915315367963,0.5143375851029162,-0.4115533912456994,0.9207797152191141,-0.5842230489234069,-0.032915728384741015,0.7699015142883784,3.601980510099323,0.9072221686279333,0.2622891279230963,0.9747001337238531,0.2013703373493341,1.4017035243632918,-1.0021412347204408,-0.08092564237043719,-0.7441656379825385,-0.36074150382824394,-0.8533136017184143,-0.04887504627384466,-0.6193847456466299,0.09320779573109034,0.48524197874422104,-0.6547618971329058,0.8663612864956289,2.217058138603211,-0.21092513401942328,-0.0648782670729416,0.23190917857868676,-0.9645715603540274,0.5432894598416556,1.0810841689575286,-0.21092513401942328,-0.8167006259673601,0.6007678594820233,3.7135134684721347,-0.12933524422973913,2.096080199744481,0.9072221686279333,0.7559915142019157,-0.9086735477231258,-0.7622139544215649,-0.6725321288961622,0.6007678594820233,-0.4285902586631195,-0.31037139890127774,1.224301699534718,-0.7803189764195482,-0.377629316099032,-0.36074150382824394,0.48524197874422104,0.061932036437784624,-1.0399582580540272,-0.1618337970909173,-0.514535240785251,-1.5143718566673,1.338953943492325,-0.5492740993843713,-0.3439027766845685,-0.377629316099032,-0.19451519653859392,-0.8533136017184143,0.5432894598416556,0.1552603482535626,3.106106395795426,0.9747001337238531,-0.22738159228350283,0.12431661965225804,-0.017000063987738737,-0.6903572636353332,-0.26043517265107846,-1.3718907863996646,1.2882713222080582,-0.6017771358819511,-0.032915728384741015,0.8800131050184969,0.8663612864956289,-0.3439027766845685,0.21665972726603153,1.9952458014491112,1.7883210270224281,-0.6547618971329058,1.658237345935038,2.314254726861213,0.21665972726603153,0.6718330237408522,-0.7441656379825385,-0.4972437792285436,0.5720990698697436,0.04623097246479662,1.3263238911225568,1.858096452664984,0.4413258066063131,-1.0971550435827746,0.3375549865593367,2.748138375991167,2.1733484536781895,0.4560011507642696,2.217058138603211,0.8663612864956289,0.014701291299391921,-0.566722147958878,4.343126506682812,0.8389623139505717,-0.6193847456466299,-0.032915728384741015,-0.22738159228350283,0.852677740649789,-0.22738159228350283,-0.017000063987738737,-0.3271128392759249,-0.31037139890127774,-0.12933524422973913,-0.31037139890127774,-0.09701742595051951,-1.331826169509489,-0.9086735477231258,0.2774200528143013,-0.04887504627384466,-0.243884846085324,0.2622891279230963,4.084595663215114,0.061932036437784624,4.00405433878558,1.1073832487263275,1.8696467178692489,-0.243884846085324,-0.26043517265107846,-0.4285902586631195,0.2925118928589216,0.8800131050184969,0.4706398114973275,-0.7984810752691569,-0.4800038669191164,-0.8717077957387307,-0.243884846085324,-0.4285902586631195,1.6462693525823706,2.5967459172501477,1.8349285964616746,0.5432894598416556,0.10878295888408213,-0.1618337970909173,-0.31037139890127774,-0.5842230489234069,-0.243884846085324,-0.1618337970909173,0.17067086843316673,-0.8349780072652183,-1.1356055001499545,-0.29367816551779385,-0.27703285170862874,0.24711890736266962,0.5432894598416556,0.9612662003264605,-0.6017771358819511,-0.11315387381905866,0.04623097246479662,0.9072221686279333,1.8811746612706568,2.303532579472338,1.4884520937953238,-0.001127805810301048,0.5720990698697436,0.8114351982042777,0.030487470396744938,-0.377629316099032,-0.31037139890127774,3.497184563628806,0.3673920803157548,0.5432894598416556,-0.4285902586631195,-0.22738159228350283,-0.4285902586631195,0.2774200528143013,0.42661358757948437,1.0546674241385827,0.8663612864956289,1.3766833583434828,0.6435101106197167,0.12431661965225804
| 2,702
|
Juvenile onset
| 17
| 38
| 2.880064
| 0.003976
|
O15118,O75027,Q03252,P38571,P35579,Q14566,P50402,Q9NR77,P06280,P54802,P02545,P51649,O14773,P07196,Q13510,P16278,P06753
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
63,312,391,389,345,296,233,78,112,50,241,181,150,185,26,93,440
|
150,63,312,2486,241,2257,112,440,185,93,2316,345,2174,389,1935,457,2436,2582,233,755,181,1463,50,658,391,2160,712,26,2307,296,1719,928,1215,1244,795,78,1757,1634
|
1.8349285964616746,2.472830381816948,1.0678905729851498,-1.0021412347204408,1.3136668502909221,-0.7261736594651729,2.040271181152975,0.7699015142883784,1.586065401491409,2.2387939765464413,-0.7803189764195482,0.9612662003264605,-0.6547618971329058,0.8800131050184969,-0.4972437792285436,0.7420485262435965,-0.9272458982666049,-1.2132888500172512,1.338953943492325,0.2925118928589216,1.6102201871058315,-0.22738159228350283,2.6577600342457113,0.42661358757948437,0.8800131050184969,-0.6370462182791121,0.35249256146592,3.0114283478612625,-0.7622139544215649,1.1335657467919271,-0.36074150382824394,0.13980900706892938,-0.0648782670729416,-0.08092564237043719,0.2622891279230963,2.3569527332268905,-0.377629316099032,-0.31037139890127774
| 2,702
|
er
| 26
| 77
| 2.878595
| 0.003995
|
Q8NHH9,P84095,Q9Y5M8,P48449,O96005,Q8NF37,O95470,O00264,O15269,O15173,Q15392,Q9Y487,Q14739,Q07065,Q9NQC3,Q96A33,Q9P2W9,O95674,Q16850,Q06136,Q8N4V1,P51572,Q969Q5,O00400,Q15363,O14735
|
Localization
|
OpenCell Localization
|
opencell_localization
|
518,514,136,396,145,405,275,159,415,33,166,41,175,179,308,442,59,438,65,204,79,469,485,352,372,379
|
159,352,973,379,33,415,1454,1122,2326,1733,1637,1735,275,438,145,2431,859,1228,2313,2151,2172,1408,2000,563,396,982,701,1201,2375,469,2094,2536,2345,823,1822,514,961,204,179,1084,532,175,927,372,166,2043,2161,65,869,1443,2500,870,79,1419,405,518,2011,1394,2012,777,485,1342,442,1372,1784,1666,1095,308,1070,875,969,1484,59,1376,1264,41,136
|
1.7531245573462935,0.9478015835630615,0.09320779573109034,0.8936333486288025,2.953902538225382,0.8114351982042777,-0.22738159228350283,-0.017000063987738737,-0.7984810752691569,-0.377629316099032,-0.3271128392759249,-0.377629316099032,1.1985189212016558,0.7699015142883784,1.8696467178692489,-0.9272458982666049,0.2013703373493341,-0.08092564237043719,-0.7803189764195482,-0.6370462182791121,-0.6547618971329058,-0.19451519653859392,-0.5318785727630885,0.5577119571515898,0.8663612864956289,0.09320779573109034,0.3673920803157548,-0.0648782670729416,-0.8533136017184143,0.7140629338857863,-0.5842230489234069,-1.0971550435827746,-0.8167006259673601,0.23190917857868676,-0.4285902586631195,0.6292972508241202,0.10878295888408213,1.463795947164361,1.6222608747574856,0.014701291299391921,0.6007678594820233,1.658237345935038,0.13980900706892938,0.9072221686279333,1.705870022831379,-0.5492740993843713,-0.6370462182791121,2.45192727608413,0.2013703373493341,-0.21092513401942328,-1.0210186165202892,0.2013703373493341,2.3463066784162883,-0.19451519653859392,0.852677740649789,0.6292972508241202,-0.5318785727630885,-0.17815150752877743,-0.5318785727630885,0.2774200528143013,0.6859434192423728,-0.14556179771058245,0.7699015142883784,-0.1618337970909173,-0.3945665116133365,-0.3271128392759249,0.014701291299391921,1.0942483489073807,0.030487470396744938,0.2013703373493341,0.10878295888408213,-0.22738159228350283,2.5351071762344404,-0.1618337970909173,-0.09701742595051951,2.8371826720644844,1.9270649969621256
| 2,702
|
Slc mediated transmembrane transport
| 12
| 22
| 2.872937
| 0.004067
|
Q70HW3,Q8TB61,O00400,Q9H2H9,Q96QD8,P35613,P53985,Q9UBX3,Q9Y6M7,P12236,Q8NEW0,P04920
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
1,258,352,198,559,328,271,144,304,614,152,502
|
352,502,860,1057,889,978,614,1381,328,1355,271,1415,1443,1,152,258,559,633,198,144,1805,304
|
0.9478015835630615,0.6435101106197167,0.2013703373493341,0.030487470396744938,0.17067086843316673,0.09320779573109034,0.48524197874422104,-0.17815150752877743,1.0014765288625636,-0.1618337970909173,1.211424359795403,-0.19451519653859392,-0.21092513401942328,4.343126506682812,1.8349285964616746,1.275532592400303,0.5720990698697436,0.4706398114973275,1.4884520937953238,1.8811746612706568,-0.4115533912456994,1.1073832487263275
| 2,702
|
Abnormality of head blood vessel
| 7
| 23
| 2.866857
| 0.004146
|
P07686,P17900,P07602,P10619,Q13510,P06865,P16278
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
160,162,4,38,26,92,93
|
1548,900,2660,92,4,160,38,2171,93,162,1233,207,1156,982,2178,1277,26,991,2444,1397,427,771,528
|
-0.27703285170862874,0.1552603482535626,-1.6816883017518833,2.249632405350508,4.00405433878558,1.7531245573462935,2.8665746612984697,-0.6547618971329058,2.2387939765464413,1.7295441678744543,-0.08092564237043719,1.4390369219353498,-0.032915728384741015,0.09320779573109034,-0.6547618971329058,-0.11315387381905866,3.0114283478612625,0.09320779573109034,-0.9272458982666049,-0.17815150752877743,0.7976231963964028,0.2925118928589216,0.6150498919054735
| 2,702
|
Splenomegaly
| 28
| 77
| 2.865788
| 0.00416
|
P07602,P38571,P36551,Q10713,Q96HY6,Q13510,P00813,Q14108,P08236,Q15392,Q9NZJ7,P33991,Q14739,P54802,Q96A33,P04062,P31749,P04066,O15118,P21964,P10253,P16278,P15586,P28070,Q9NZ08,P02545,P61916,P14174
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,389,269,397,272,26,27,29,158,166,427,42,175,50,442,188,189,439,63,207,220,93,221,355,250,241,248,122
|
2148,2190,2672,2516,456,63,1811,2550,817,2024,2563,27,241,188,439,2650,1198,2475,1429,4,158,220,889,1519,2258,1350,2062,2669,122,221,93,1081,2196,1101,207,1554,1998,355,615,2029,189,42,269,1591,389,924,1182,720,1593,1463,2178,2071,50,2630,248,397,749,26,29,175,2652,166,1064,2510,488,542,1690,727,2444,1397,442,272,1215,1097,250,427,2167
|
-0.6370462182791121,-0.6725321288961622,-1.9200896765948166,-1.0589605873257606,0.7420485262435965,2.472830381816948,-0.4285902586631195,-1.1356055001499545,0.23190917857868676,-0.5492740993843713,-1.174315546728808,3.0018786097104724,1.3136668502909221,1.549648138953408,0.7699015142883784,-1.5765412690495015,-0.0648782670729416,-0.983325689072196,-0.21092513401942328,4.00405433878558,1.7648798340833782,1.3892066414158972,0.17067086843316673,-0.26043517265107846,-0.7261736594651729,-0.1618337970909173,-0.566722147958878,-1.7457215321911723,1.983936246561302,1.3892066414158972,2.2387939765464413,0.014701291299391921,-0.6725321288961622,-0.001127805810301048,1.4390369219353498,-0.27703285170862874,-0.5318785727630885,0.9478015835630615,0.48524197874422104,-0.5492740993843713,1.549648138953408,2.7878758792557337,1.224301699534718,-0.29367816551779385,0.8800131050184969,0.13980900706892938,-0.04887504627384466,0.3375549865593367,-0.29367816551779385,-0.22738159228350283,-0.6547618971329058,-0.566722147958878,2.6577600342457113,-1.4325193129919627,1.3009827009421377,0.8663612864956289,0.30756485716682186,3.0114283478612625,3.0018786097104724,1.658237345935038,-1.5765412690495015,1.705870022831379,0.030487470396744938,-1.0399582580540272,0.6718330237408522,0.5864509778300103,-0.3439027766845685,0.3375549865593367,-0.9272458982666049,-0.17815150752877743,0.7699015142883784,1.211424359795403,-0.0648782670729416,0.014701291299391921,1.3009827009421377,0.7976231963964028,-0.6370462182791121
| 2,702
|
Cherry red spot of the macula
| 6
| 9
| 2.861285
| 0.004219
|
P07686,P07602,P10619,Q13510,P06865,P16278
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
160,4,38,26,92,93
|
92,4,160,38,2171,93,162,26,427
|
2.249632405350508,4.00405433878558,1.7531245573462935,2.8665746612984697,-0.6547618971329058,2.2387939765464413,1.7295441678744543,3.0114283478612625,0.7976231963964028
| 2,702
|
Phenotypic variability
| 38
| 83
| 2.860509
| 0.00423
|
Q70HW3,P07602,Q15058,Q9UBB4,Q13868,P36551,Q92733,Q13813,O95470,P09622,Q13510,Q9UEY8,P17900,Q9NZJ7,O14578,P07196,Q8TD16,P06753,P04350,O60313,O43707,P52732,Q9NR77,Q9BVA1,Q9Y3Z3,P49792,P00403,Q6PI48,Q6P4A7,P00374,Q13885,Q9Y5P6,Q53H12,P43243,P02545,Q9Y263,P50995,O14979
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,4,515,525,267,269,406,533,275,25,26,546,162,427,421,185,313,440,449,326,582,329,78,466,342,594,338,479,97,602,357,497,237,616,241,508,630,251
|
2687,1320,1099,421,251,582,326,1406,2024,275,602,338,241,449,440,185,4,2417,25,889,162,1431,2027,690,840,269,2433,1876,2409,2452,1968,1904,616,1648,1383,594,1649,630,984,329,1879,2094,2135,658,2035,2160,1331,1857,2037,26,533,267,357,1718,515,1208,237,1416,1657,1722,97,479,1,313,631,406,706,850,466,2101,1315,78,427,525,2429,546,1543,508,1758,708,342,783,497
|
-2.830790652033712,-0.14556179771058245,-0.001127805810301048,0.7976231963964028,1.2882713222080582,0.5288313967073893,1.014819277244463,-0.19451519653859392,-0.5492740993843713,1.1985189212016558,0.4998078409542412,0.9747001337238531,1.3136668502909221,0.7559915142019157,0.7699015142883784,1.586065401491409,4.00405433878558,-0.9086735477231258,3.0399875010519266,0.17067086843316673,1.7295441678744543,-0.21092513401942328,-0.5492740993843713,0.382253743928895,0.21665972726603153,1.224301699534718,-0.9272458982666049,-0.462815185693309,-0.8901609796463711,-0.9458784336451688,-0.514535240785251,-0.4800038669191164,0.48524197874422104,-0.3271128392759249,-0.17815150752877743,0.5143375851029162,-0.3271128392759249,0.4706398114973275,0.09320779573109034,1.0014765288625636,-0.462815185693309,-0.5842230489234069,-0.6193847456466299,0.42661358757948437,-0.5492740993843713,-0.6370462182791121,-0.14556179771058245,-0.4456774203599463,-0.5492740993843713,3.0114283478612625,0.6007678594820233,1.237151067189716,0.9478015835630615,-0.36074150382824394,0.6292972508241202,-0.0648782670729416,1.3263238911225568,-0.19451519653859392,-0.3271128392759249,-0.36074150382824394,2.217058138603211,0.700019999999374,4.343126506682812,1.0678905729851498,0.4706398114973275,0.852677740649789,0.3673920803157548,0.21665972726603153,0.7280723875131836,-0.5842230489234069,-0.12933524422973913,2.3569527332268905,0.7976231963964028,0.6150498919054735,-0.9086735477231258,0.5864509778300103,-0.26043517265107846,0.6435101106197167,-0.377629316099032,0.3673920803157548,0.9747001337238531,0.2774200528143013,0.6718330237408522
| 2,702
|
Golgi membrane
| 38
| 110
| 2.86033
| 0.004232
|
Q8TB61,Q8N2H4,Q9BUR5,O95070,Q10713,O95197,P24390,Q8NF37,Q9HD26,Q8IV08,Q8IZA0,Q13190,O43505,Q14108,P11717,Q14789,Q15392,P10321,Q10472,Q9BW83,Q92896,Q9P2W9,Q9Y282,P35613,Q8N4V1,P51572,P52292,Q16706,O00400,O95721,Q8NBN3,O95249,O15260,P51790,Q6ZRP7,Q15363,O00461,Q9Y3B3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
258,132,393,386,397,142,15,405,538,19,278,532,282,29,417,418,166,423,554,435,183,59,62,328,79,469,90,478,352,353,108,364,109,242,505,372,126,130
|
1319,352,126,710,2516,1759,1453,109,1121,282,1810,1959,1490,1733,386,142,364,353,2487,1380,423,889,417,1555,15,1234,328,2174,1819,604,1460,1765,1327,701,1969,755,1201,469,242,90,822,2156,2376,1006,2283,1794,823,1905,1823,1594,1278,2694,1715,1062,554,1494,397,1133,532,618,29,418,926,1335,372,166,2138,478,963,1691,505,1186,2164,713,19,278,132,79,738,108,405,258,2012,929,183,669,393,752,435,1169,1094,635,949,538,875,1172,1484,59,1867,2600,1893,2570,1376,62,1988,2647,569,130,1264,936
|
-0.14556179771058245,0.9478015835630615,1.9726052400824703,0.35249256146592,-1.0589605873257606,-0.3945665116133365,-0.22738159228350283,2.0626573264796644,-0.017000063987738737,1.1855852561088989,-0.4285902586631195,-0.514535240785251,-0.243884846085324,-0.377629316099032,0.8800131050184969,1.8811746612706568,0.9207797152191141,0.9478015835630615,-1.0021412347204408,-0.17815150752877743,0.7976231963964028,0.17067086843316673,0.8114351982042777,-0.27703285170862874,3.4883696583674233,-0.08092564237043719,1.0014765288625636,-0.6547618971329058,-0.4285902586631195,0.4998078409542412,-0.22738159228350283,-0.3945665116133365,-0.14556179771058245,0.3673920803157548,-0.514535240785251,0.2925118928589216,-0.0648782670729416,0.7140629338857863,1.3136668502909221,2.282030613119506,0.23190917857868676,-0.6370462182791121,-0.8533136017184143,0.07759089922445578,-0.7441656379825385,-0.4115533912456994,0.23190917857868676,-0.4800038669191164,-0.4285902586631195,-0.29367816551779385,-0.11315387381905866,-5.875733142878054,-0.36074150382824394,0.030487470396744938,0.5720990698697436,-0.243884846085324,0.8663612864956289,-0.017000063987738737,0.6007678594820233,0.48524197874422104,3.0018786097104724,0.8114351982042777,0.13980900706892938,-0.14556179771058245,0.9072221686279333,1.705870022831379,-0.6193847456466299,0.700019999999374,0.10878295888408213,-0.3439027766845685,0.6435101106197167,-0.04887504627384466,-0.6370462182791121,0.35249256146592,3.2085718590601604,1.1985189212016558,1.94987853311504,2.3463066784162883,0.32257915315367963,2.0849599804357837,0.852677740649789,1.275532592400303,-0.5318785727630885,0.13980900706892938,1.598155063758245,0.41186430071853863,0.8800131050184969,0.30756485716682186,0.7837786881907414,-0.032915728384741015,0.014701291299391921,0.4706398114973275,0.12431661965225804,0.6007678594820233,0.2013703373493341,-0.032915728384741015,-0.22738159228350283,2.5351071762344404,-0.4456774203599463,-1.2722506277254433,-0.462815185693309,-1.174315546728808,-0.1618337970909173,2.4832547399290448,-0.514535240785251,-1.5350197765489455,0.5577119571515898,1.9612526973306057,-0.09701742595051951,0.13980900706892938
| 2,702
|
Nuclear inner membrane
| 13
| 18
| 2.859226
| 0.004247
|
Q03252,Q99720,Q9UH99,P50402,Q14739,P43243,Q9H1E5,O75844,Q8IXM6,P20700,P61970,Q9Y2U8,P62995
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
391,5,560,233,175,616,177,147,404,309,23,581,339
|
147,1174,309,1712,616,233,23,339,391,842,175,651,404,5,1538,177,560,581
|
1.858096452664984,-0.04887504627384466,1.0810841689575286,-0.36074150382824394,0.48524197874422104,1.338953943492325,3.106106395795426,0.9747001337238531,0.8800131050184969,0.21665972726603153,1.658237345935038,0.4413258066063131,0.852677740649789,4.00405433878558,-0.26043517265107846,1.6462693525823706,0.5720990698697436,0.5432894598416556
| 2,702
|
Arthritis
| 15
| 35
| 2.856491
| 0.004284
|
O15460,P28070,P14174,Q9NZ08,Q14739,Q96HY6,P21964,P06280,O75844,Q9Y3Z3,P02545,Q7Z406,Q13510,P04062,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
195,355,122,250,175,272,207,112,147,342,241,383,26,188,29
|
1219,195,147,2168,241,188,112,2417,423,2315,122,207,2505,355,1182,720,1463,2376,2178,1102,1563,1882,26,29,175,1858,383,1367,727,2444,1397,272,250,581,342
|
-0.08092564237043719,1.500741864308918,1.858096452664984,-0.6547618971329058,1.3136668502909221,1.549648138953408,2.040271181152975,-0.9086735477231258,0.7976231963964028,-0.7803189764195482,1.983936246561302,1.4390369219353498,-1.0399582580540272,0.9478015835630615,-0.04887504627384466,0.3375549865593367,-0.22738159228350283,-0.8533136017184143,-0.6547618971329058,-0.001127805810301048,-0.27703285170862874,-0.462815185693309,3.0114283478612625,3.0018786097104724,1.658237345935038,-0.4456774203599463,0.8936333486288025,-0.1618337970909173,0.3375549865593367,-0.9272458982666049,-0.17815150752877743,1.211424359795403,1.3009827009421377,0.5432894598416556,0.9747001337238531
| 2,702
|
Carbohydrate derivative catabolic process
| 15
| 31
| 2.851556
| 0.004351
|
Q9H773,P07686,P17900,O60502,Q9NUJ1,P06865,P06280,Q9BTY2,P54802,P16278,Q13126,P00813,P04062,P15586,P08236
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,160,162,74,333,92,112,307,50,93,24,27,188,221,158
|
2131,74,2563,2168,27,188,439,112,92,160,158,221,93,162,2450,2173,2682,1741,1200,50,605,24,2099,2011,1777,307,2654,129,333,2366,342
|
-0.6193847456466299,2.378188367259261,-1.174315546728808,-0.6547618971329058,3.0018786097104724,1.549648138953408,0.7699015142883784,2.040271181152975,2.249632405350508,1.7531245573462935,1.7648798340833782,1.3892066414158972,2.2387939765464413,1.7295441678744543,-0.9458784336451688,-0.6547618971329058,-2.0999874374202814,-0.377629316099032,-0.0648782670729416,2.6577600342457113,0.4998078409542412,3.0778580474948067,-0.5842230489234069,-0.5318785727630885,-0.3945665116133365,1.0942483489073807,-1.5765412690495015,1.9612526973306057,1.0014765288625636,-0.8349780072652183,0.9747001337238531
| 2,702
|
Abnormality of the spleen
| 34
| 101
| 2.837988
| 0.00454
|
P07602,P38571,P36551,Q10713,Q96HY6,Q13510,P00813,Q14108,P08236,P07686,Q9UJS0,P10619,Q15392,Q9NZJ7,P33991,Q14739,P54802,Q96A33,O96028,P04062,P31749,P04066,O15118,P21964,Q9Y3Z3,P10253,P16278,P15586,P28070,Q9NZ08,O95202,P02545,P61916,P14174
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,389,269,397,272,26,27,29,158,160,420,38,166,427,42,175,50,442,187,188,189,439,63,207,342,220,93,221,355,250,363,241,248,122
|
2148,2190,2672,2516,456,63,1811,2550,817,2579,363,2024,187,2563,27,241,188,439,2650,1198,2475,1429,4,160,158,1963,220,38,889,1519,2258,1350,2062,2669,122,221,93,1081,2196,1101,207,1554,1998,355,615,2029,189,42,269,1591,389,1935,2452,1968,924,1182,679,720,2583,1593,1463,2178,2071,50,1102,2630,248,1746,397,749,2117,26,1617,29,175,2652,166,1064,2510,488,542,1690,2165,727,1693,2444,1397,442,272,1779,2385,1215,1097,250,427,2167,420,1956,581,342,1704
|
-0.6370462182791121,-0.6725321288961622,-1.9200896765948166,-1.0589605873257606,0.7420485262435965,2.472830381816948,-0.4285902586631195,-1.1356055001499545,0.23190917857868676,-1.2132888500172512,0.9207797152191141,-0.5492740993843713,1.561812043982834,-1.174315546728808,3.0018786097104724,1.3136668502909221,1.549648138953408,0.7699015142883784,-1.5765412690495015,-0.0648782670729416,-0.983325689072196,-0.21092513401942328,4.00405433878558,1.7531245573462935,1.7648798340833782,-0.514535240785251,1.3892066414158972,2.8665746612984697,0.17067086843316673,-0.26043517265107846,-0.7261736594651729,-0.1618337970909173,-0.566722147958878,-1.7457215321911723,1.983936246561302,1.3892066414158972,2.2387939765464413,0.014701291299391921,-0.6725321288961622,-0.001127805810301048,1.4390369219353498,-0.27703285170862874,-0.5318785727630885,0.9478015835630615,0.48524197874422104,-0.5492740993843713,1.549648138953408,2.7878758792557337,1.224301699534718,-0.29367816551779385,0.8800131050184969,-0.4972437792285436,-0.9458784336451688,-0.514535240785251,0.13980900706892938,-0.04887504627384466,0.39707775152061925,0.3375549865593367,-1.2132888500172512,-0.29367816551779385,-0.22738159228350283,-0.6547618971329058,-0.566722147958878,2.6577600342457113,-0.001127805810301048,-1.4325193129919627,1.3009827009421377,-0.377629316099032,0.8663612864956289,0.30756485716682186,-0.6017771358819511,3.0114283478612625,-0.31037139890127774,3.0018786097104724,1.658237345935038,-1.5765412690495015,1.705870022831379,0.030487470396744938,-1.0399582580540272,0.6718330237408522,0.5864509778300103,-0.3439027766845685,-0.6370462182791121,0.3375549865593367,-0.3439027766845685,-0.9272458982666049,-0.17815150752877743,0.7699015142883784,1.211424359795403,-0.3945665116133365,-0.8533136017184143,-0.0648782670729416,0.014701291299391921,1.3009827009421377,0.7976231963964028,-0.6370462182791121,0.8114351982042777,-0.4972437792285436,0.5432894598416556,0.9747001337238531,-0.3439027766845685
| 2,702
|
Ceramide metabolic process
| 8
| 16
| 2.834758
| 0.004586
|
P07686,P17900,Q53H12,P06280,P04062,Q96G23,Q13510,P06865
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,162,237,112,188,120,26,92
|
415,1454,275,188,112,92,160,162,1179,26,2671,237,643,120,848,1172
|
0.8114351982042777,-0.22738159228350283,1.1985189212016558,1.549648138953408,2.040271181152975,2.249632405350508,1.7531245573462935,1.7295441678744543,-0.04887504627384466,3.0114283478612625,-1.7672271447732948,1.3263238911225568,0.4560011507642696,1.9952458014491112,0.21665972726603153,-0.032915728384741015
| 2,702
|
Membrane lipid catabolic process
| 7
| 11
| 2.82865
| 0.004674
|
P07686,P50897,P17900,P06280,P04062,Q13510,P06865
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,3,162,112,188,26,92
|
275,188,439,112,92,160,162,3,26,545,1172
|
1.1985189212016558,1.549648138953408,0.7699015142883784,2.040271181152975,2.249632405350508,1.7531245573462935,1.7295441678744543,4.03639791939681,3.0114283478612625,0.5864509778300103,-0.032915728384741015
| 2,702
|
secondary carrier transporter
| 9
| 15
| 2.822387
| 0.004767
|
Q8TB61,O00400,Q9UJS0,Q6NT16,O95202,Q9Y6M7,Q9UBX3,Q9BQT8,Q96ES6
|
Functions
|
Panther Protein class
|
panther_protein_class
|
258,352,420,37,363,304,144,146,279
|
352,921,363,502,1159,37,1443,258,279,146,609,144,420,1805,304
|
0.9478015835630615,0.13980900706892938,0.9207797152191141,0.6435101106197167,-0.032915728384741015,2.886090180376803,-0.21092513401942328,1.275532592400303,1.1985189212016558,1.8696467178692489,0.4998078409542412,1.8811746612706568,0.8114351982042777,-0.4115533912456994,1.1073832487263275
| 2,702
|
Abnormal circulating cholesterol concentration
| 15
| 29
| 2.822048
| 0.004772
|
Q9BV10,Q9UBM7,Q9UJS0,P07602,Q15392,P38571,Q9NZJ7,P50402,Q15800,Q14739,Q15904,O75431,P02545,P61916,P37268
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
320,359,420,4,166,389,427,233,367,175,488,499,241,248,154
|
499,241,1611,4,154,389,1740,2436,233,2583,658,248,1882,1062,828,1257,175,166,2043,367,488,1240,506,1538,320,580,427,359,420
|
0.6576886443457405,1.3136668502909221,-0.31037139890127774,4.00405433878558,1.8233108238857811,0.8800131050184969,-0.377629316099032,-0.9272458982666049,1.338953943492325,-1.2132888500172512,0.42661358757948437,1.3009827009421377,-0.462815185693309,0.030487470396744938,0.23190917857868676,-0.09701742595051951,1.658237345935038,1.705870022831379,-0.5492740993843713,0.9207797152191141,0.6718330237408522,-0.08092564237043719,0.6435101106197167,-0.26043517265107846,1.0414145845970093,0.5432894598416556,0.7976231963964028,0.9478015835630615,0.8114351982042777
| 2,702
|
Negative regulation of mrna metabolic process
| 24
| 43
| 2.821715
| 0.004777
|
O75150,Q99729,P16989,P26368,Q5VTR2,Q9Y2W1,Q07021,Q13242,Q92804,P98175,P07910,P35637,Q14103,Q9H074,Q15287,P38159,Q16629,Q13151,O60506,P22626,O75494,P67809,Q13247,P61978
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
754,268,287,666,556,687,553,318,194,322,450,203,464,729,597,212,607,723,227,354,361,365,617,243
|
1402,1606,227,754,361,1197,450,773,287,1457,354,666,1432,203,212,800,243,365,322,1330,553,1083,1103,2284,1203,723,318,617,464,597,944,1655,607,556,1771,1366,1259,1832,194,268,729,851,687
|
-0.19451519653859392,-0.31037139890127774,1.364133559046907,0.2925118928589216,0.9343061375179438,-0.0648782670729416,0.7559915142019157,0.2774200528143013,1.1726232359899564,-0.22738159228350283,0.9478015835630615,0.41186430071853863,-0.21092513401942328,1.463795947164361,1.4141741225146764,0.24711890736266962,1.3136668502909221,0.9207797152191141,1.0281319155612654,-0.14556179771058245,0.5720990698697436,0.014701291299391921,-0.001127805810301048,-0.7441656379825385,-0.0648782670729416,0.3375549865593367,1.0414145845970093,0.48524197874422104,0.7280723875131836,0.5143375851029162,0.12431661965225804,-0.3271128392759249,0.4998078409542412,0.5720990698697436,-0.3945665116133365,-0.1618337970909173,-0.09701742595051951,-0.4285902586631195,1.5130062457371627,1.237151067189716,0.3375549865593367,0.21665972726603153,0.39707775152061925
| 2,702
|
Hyperlipidemia
| 11
| 24
| 2.788425
| 0.005296
|
Q9UJS0,P28070,P38571,P22830,P50402,P23786,P06280,O75844,O75431,P02545,O95470
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
420,355,389,7,233,105,112,147,499,241,275
|
1548,582,499,147,275,241,112,1611,7,105,355,2028,1061,389,1327,233,2071,828,1257,506,1284,1538,420,1956
|
-0.27703285170862874,0.5288313967073893,0.6576886443457405,1.858096452664984,1.1985189212016558,1.3136668502909221,2.040271181152975,-0.31037139890127774,3.7135134684721347,2.096080199744481,0.9478015835630615,-0.5492740993843713,0.030487470396744938,0.8800131050184969,-0.14556179771058245,1.338953943492325,-0.566722147958878,0.23190917857868676,-0.09701742595051951,0.6435101106197167,-0.11315387381905866,-0.26043517265107846,0.8114351982042777,-0.4972437792285436
| 2,702
|
Lipid droplet
| 10
| 27
| 2.784262
| 0.005365
|
Q99720,Q9H6V9,Q8NBX0,P48449,Q8NF37,O43760,Q07065,Q01105,Q8N0X7,Q9H8H3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
5,8,75,396,405,81,179,470,217,315
|
1489,81,1732,1034,1427,2431,2193,1229,396,1525,1410,469,2094,470,179,2043,217,75,405,929,965,5,8,315,1666,2105,1515
|
-0.243884846085324,2.3356417057869807,-0.377629316099032,0.04623097246479662,-0.21092513401942328,-0.9272458982666049,-0.6725321288961622,-0.08092564237043719,0.8663612864956289,-0.26043517265107846,-0.19451519653859392,0.7140629338857863,-0.5842230489234069,0.7140629338857863,1.6222608747574856,-0.5492740993843713,1.4017035243632918,2.367579939782527,0.852677740649789,0.13980900706892938,0.10878295888408213,4.00405433878558,3.627900422577668,1.0546674241385827,-0.3271128392759249,-0.5842230489234069,-0.243884846085324
| 2,702
|
Biliary tract abnormality
| 11
| 24
| 2.780365
| 0.00543
|
P07602,Q9NZJ7,Q10713,P09601,Q14739,O95202,P02545,P14174,O96028,P04062,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,427,397,334,175,363,241,122,187,188,29
|
467,363,187,241,188,4,334,122,2561,1523,983,1593,397,749,2117,29,175,726,1536,897,427,1399,1758,1634
|
0.7140629338857863,0.9207797152191141,1.561812043982834,1.3136668502909221,1.549648138953408,4.00405433878558,0.9881035286247505,1.983936246561302,-1.1549278473496636,-0.26043517265107846,0.09320779573109034,-0.29367816551779385,0.8663612864956289,0.30756485716682186,-0.6017771358819511,3.0018786097104724,1.658237345935038,0.3375549865593367,-0.26043517265107846,0.17067086843316673,0.7976231963964028,-0.17815150752877743,-0.377629316099032,-0.31037139890127774
| 2,702
|
Variable expressivity
| 27
| 67
| 2.777383
| 0.00548
|
Q70HW3,P07602,Q15058,Q13868,Q13813,O95470,P09622,Q13510,P17900,Q9NZJ7,O14578,P07196,Q8TD16,P06753,P04350,P52732,Q9BVA1,Q9NR77,Q9Y3Z3,P00403,Q6PI48,Q6P4A7,Q13885,Q9Y5P6,Q53H12,P02545,Q9Y263
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,4,515,267,533,275,25,26,162,427,421,185,313,440,449,329,466,78,342,338,479,97,357,497,237,241,508
|
2687,1320,1099,421,582,1406,2024,275,602,338,241,449,440,185,4,2417,25,889,162,2027,690,1876,2409,2452,1904,616,1648,1383,1649,329,1879,2094,2135,658,2035,2160,1331,1857,2037,26,533,267,357,1718,515,1208,237,1416,1657,97,479,1,313,850,466,2101,1315,78,427,2429,546,508,1758,708,342,783,497
|
-2.830790652033712,-0.14556179771058245,-0.001127805810301048,0.7976231963964028,0.5288313967073893,-0.19451519653859392,-0.5492740993843713,1.1985189212016558,0.4998078409542412,0.9747001337238531,1.3136668502909221,0.7559915142019157,0.7699015142883784,1.586065401491409,4.00405433878558,-0.9086735477231258,3.0399875010519266,0.17067086843316673,1.7295441678744543,-0.5492740993843713,0.382253743928895,-0.462815185693309,-0.8901609796463711,-0.9458784336451688,-0.4800038669191164,0.48524197874422104,-0.3271128392759249,-0.17815150752877743,-0.3271128392759249,1.0014765288625636,-0.462815185693309,-0.5842230489234069,-0.6193847456466299,0.42661358757948437,-0.5492740993843713,-0.6370462182791121,-0.14556179771058245,-0.4456774203599463,-0.5492740993843713,3.0114283478612625,0.6007678594820233,1.237151067189716,0.9478015835630615,-0.36074150382824394,0.6292972508241202,-0.0648782670729416,1.3263238911225568,-0.19451519653859392,-0.3271128392759249,2.217058138603211,0.700019999999374,4.343126506682812,1.0678905729851498,0.21665972726603153,0.7280723875131836,-0.5842230489234069,-0.12933524422973913,2.3569527332268905,0.7976231963964028,-0.9086735477231258,0.5864509778300103,0.6435101106197167,-0.377629316099032,0.3673920803157548,0.9747001337238531,0.2774200528143013,0.6718330237408522
| 2,702
|
Mitochondrial substrate/solute carrier [IPR018108]
| 9
| 18
| 2.777004
| 0.005486
|
Q9Y619,Q70HW3,Q9UJS0,Q9NZJ7,Q9UBX3,Q9BQT8,O43772,Q9H2D1,O43808
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
226,1,420,427,144,146,83,53,337
|
83,337,921,860,978,614,2115,1159,642,1,146,53,896,427,144,420,226,509
|
2.3249577453845984,0.9747001337238531,0.13980900706892938,0.2013703373493341,0.09320779573109034,0.48524197874422104,-0.6017771358819511,-0.032915728384741015,0.4560011507642696,4.343126506682812,1.8696467178692489,2.5967459172501477,0.17067086843316673,0.7976231963964028,1.8811746612706568,0.8114351982042777,1.3766833583434828,0.6435101106197167
| 2,702
|
SLC25 family of mitochondrial transporters
| 9
| 18
| 2.777004
| 0.005486
|
Q9Y619,Q70HW3,Q9UJS0,Q9NZJ7,Q9UBX3,Q9BQT8,O43772,Q9H2D1,O43808
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
226,1,420,427,144,146,83,53,337
|
83,337,921,860,978,614,2115,1159,642,1,146,53,896,427,144,420,226,509
|
2.3249577453845984,0.9747001337238531,0.13980900706892938,0.2013703373493341,0.09320779573109034,0.48524197874422104,-0.6017771358819511,-0.032915728384741015,0.4560011507642696,4.343126506682812,1.8696467178692489,2.5967459172501477,0.17067086843316673,0.7976231963964028,1.8811746612706568,0.8114351982042777,1.3766833583434828,0.6435101106197167
| 2,702
|
Mitochondrial carrier domain superfamily [IPR023395]
| 9
| 18
| 2.777004
| 0.005486
|
Q9Y619,Q70HW3,Q9UJS0,Q9NZJ7,Q9UBX3,Q9BQT8,O43772,Q9H2D1,O43808
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
226,1,420,427,144,146,83,53,337
|
83,337,921,860,978,614,2115,1159,642,1,146,53,896,427,144,420,226,509
|
2.3249577453845984,0.9747001337238531,0.13980900706892938,0.2013703373493341,0.09320779573109034,0.48524197874422104,-0.6017771358819511,-0.032915728384741015,0.4560011507642696,4.343126506682812,1.8696467178692489,2.5967459172501477,0.17067086843316673,0.7976231963964028,1.8811746612706568,0.8114351982042777,1.3766833583434828,0.6435101106197167
| 2,702
|
Ectopic calcification
| 16
| 43
| 2.776802
| 0.00549
|
Q9UBM7,O00584,O60313,P38571,P23786,O75381,Q14739,O00116,O75844,Q9Y3Z3,P02545,P38435,P00403,P04062,P08236,P40855
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
359,131,326,389,105,301,175,461,147,342,241,86,338,188,158,288
|
461,1099,131,688,644,326,1811,2404,301,499,147,2024,338,241,188,1429,158,1154,889,1552,1021,1176,105,840,86,389,288,1968,983,1593,756,1102,2037,175,990,2043,2267,897,1097,1375,359,342,2621
|
0.7280723875131836,-0.001127805810301048,1.94987853311504,0.382253743928895,0.4413258066063131,1.014819277244463,-0.4285902586631195,-0.8901609796463711,1.1073832487263275,0.6576886443457405,1.858096452664984,-0.5492740993843713,0.9747001337238531,1.3136668502909221,1.549648138953408,-0.21092513401942328,1.7648798340833782,-0.032915728384741015,0.17067086843316673,-0.27703285170862874,0.061932036437784624,-0.04887504627384466,2.096080199744481,0.21665972726603153,2.303532579472338,0.8800131050184969,1.1726232359899564,-0.514535240785251,0.09320779573109034,-0.29367816551779385,0.2925118928589216,-0.001127805810301048,-0.5492740993843713,1.658237345935038,0.09320779573109034,-0.5492740993843713,-0.7261736594651729,0.17067086843316673,0.014701291299391921,-0.1618337970909173,0.9478015835630615,0.9747001337238531,-1.3518233822249164
| 2,702
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 11
| 28
| 2.773567
| 0.005545
|
P13674,Q16850,P30519,O15460,Q9BU89,P09601,Q15800,P61457,Q14534,Q8NB78,Q32P28
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
161,65,35,195,173,334,367,208,311,186,225
|
2463,973,195,613,656,2058,1609,799,718,334,161,388,1711,35,208,1528,1616,311,367,65,225,1107,652,1979,186,173,2484,1015
|
-0.9645715603540274,0.09320779573109034,1.500741864308918,0.48524197874422104,0.42661358757948437,-0.566722147958878,-0.31037139890127774,0.24711890736266962,0.3375549865593367,0.9881035286247505,1.7413460338386124,0.8800131050184969,-0.36074150382824394,2.915245805395765,1.4390369219353498,-0.26043517265107846,-0.31037139890127774,1.0810841689575286,0.9207797152191141,2.45192727608413,1.3766833583434828,-0.001127805810301048,0.4413258066063131,-0.514535240785251,1.5739510964183674,1.6701813099617207,-0.983325689072196,0.07759089922445578
| 2,702
|
Intrinsic component of mitochondrial membrane
| 16
| 44
| 2.771769
| 0.005575
|
Q6P4A7,Q99595,Q8TB36,Q9BUR5,Q53H12,Q9Y2R0,P57105,Q9BPX6,Q15388,O75431,Q15070,Q8IWA4,O14925,O75880,Q13505,Q9NX63
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
97,2,484,393,237,14,431,303,366,499,85,373,344,529,156,350
|
344,499,529,1225,1151,785,978,1199,2318,431,2115,156,85,366,845,2556,555,237,726,97,1089,373,995,1981,1660,484,2427,1503,2,303,765,393,1139,968,1629,1509,896,808,350,1117,1844,14,783,663
|
0.9612662003264605,0.6576886443457405,0.6007678594820233,-0.08092564237043719,-0.032915728384741015,0.2622891279230963,0.09320779573109034,-0.0648782670729416,-0.7803189764195482,0.7837786881907414,-0.6017771358819511,1.7883210270224281,2.314254726861213,0.9207797152191141,0.21665972726603153,-1.1356055001499545,0.5720990698697436,1.3263238911225568,0.3375549865593367,2.217058138603211,0.014701291299391921,0.9072221686279333,0.09320779573109034,-0.514535240785251,-0.3271128392759249,0.6859434192423728,-0.9086735477231258,-0.243884846085324,4.084595663215114,1.1073832487263275,0.2925118928589216,0.8800131050184969,-0.017000063987738737,0.10878295888408213,-0.31037139890127774,-0.243884846085324,0.17067086843316673,0.24711890736266962,0.9612662003264605,-0.001127805810301048,-0.4285902586631195,3.497184563628806,0.2774200528143013,0.42661358757948437
| 2,702
|
Arteriosclerosis
| 6
| 13
| 2.771536
| 0.005579
|
O15118,O75844,P02545,P38435,Q13510,P16278
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
63,147,241,86,26,93
|
63,2353,147,241,93,1021,1176,2234,86,389,248,26,1367
|
2.472830381816948,-0.8349780072652183,1.858096452664984,1.3136668502909221,2.2387939765464413,0.061932036437784624,-0.04887504627384466,-0.7082376548394596,2.303532579472338,0.8800131050184969,1.3009827009421377,3.0114283478612625,-0.1618337970909173
| 2,702
|
External side of plasma membrane
| 10
| 20
| 2.770812
| 0.005592
|
O15439,Q9H2H9,P11279,P41440,O75955,O96005,P51790,P08183,P42892,P00813
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
380,198,387,457,422,145,242,54,55,27
|
380,422,145,1227,27,665,818,957,718,54,387,1300,1998,457,55,1182,242,2285,483,198
|
0.8936333486288025,0.7976231963964028,1.8696467178692489,-0.08092564237043719,3.0018786097104724,0.41186430071853863,0.23190917857868676,0.10878295888408213,0.3375549865593367,2.5762697271805473,0.8800131050184969,-0.12933524422973913,-0.5318785727630885,0.7420485262435965,2.5660054539144865,-0.04887504627384466,1.3136668502909221,-0.7441656379825385,0.6859434192423728,1.4884520937953238
| 2,702
|
Abnormal tissue metabolite concentration
| 8
| 12
| 2.7516
| 0.00593
|
P07686,P17900,P07602,Q9NZJ7,O75381,P06280,P06865,P40855
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
160,162,4,427,301,112,92,288
|
467,301,112,92,4,160,162,288,983,1593,427,1758
|
0.7140629338857863,1.1073832487263275,2.040271181152975,2.249632405350508,4.00405433878558,1.7531245573462935,1.7295441678744543,1.1726232359899564,0.09320779573109034,-0.29367816551779385,0.7976231963964028,-0.377629316099032
| 2,702
|
Porphyrin containing compound metabolic process
| 8
| 14
| 2.750714
| 0.005947
|
P30536,P30519,P22830,P33527,P36551,P09601,O75027,O00264
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
289,35,7,13,269,334,312,159
|
159,312,334,7,1178,35,289,13,269,1743,1657,409,2666,1375
|
1.7531245573462935,1.0678905729851498,0.9881035286247505,3.7135134684721347,-0.04887504627384466,2.915245805395765,1.1596327314267856,3.497184563628806,1.224301699534718,-0.377629316099032,-0.3271128392759249,0.8389623139505717,-1.7029527383730034,-0.1618337970909173
| 2,702
|
Active transmembrane transporter activity
| 32
| 72
| 2.747098
| 0.006013
|
O15439,P13073,P33527,P53985,Q9UBX3,O43676,Q96ES6,Q7KZN9,P05023,Q9Y5K8,Q96QD8,Q9Y6M7,P08183,O75027,P16615,P20674,Q9HD20,Q9H2H9,P41440,O95169,P00403,Q9UDW1,P06576,Q9BXP2,O00400,Q15388,O95202,P28288,P51790,Q9P0J0,O96000,P04920
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
380,395,13,271,144,20,279,409,539,561,559,304,54,312,441,572,69,198,457,592,338,87,215,609,352,366,363,615,242,375,369,502
|
2687,352,1586,380,20,1895,312,2531,1608,1322,1517,731,592,1787,363,2088,369,338,502,539,1252,860,215,54,1057,1230,1175,978,614,395,441,2465,1022,572,1101,2406,941,615,2418,2197,13,1082,1876,457,2642,242,1463,1680,271,841,1278,2115,1159,366,1415,2290,1944,409,1660,279,559,609,198,69,375,144,87,1217,1805,561,304,953
|
-2.830790652033712,0.9478015835630615,-0.29367816551779385,0.8936333486288025,3.1993280187186217,-0.4800038669191164,1.0678905729851498,-1.0971550435827746,-0.31037139890127774,-0.14556179771058245,-0.26043517265107846,0.32257915315367963,0.5143375851029162,-0.4115533912456994,0.9207797152191141,-0.5842230489234069,0.9072221686279333,0.9747001337238531,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,1.4017035243632918,2.5762697271805473,0.030487470396744938,-0.08092564237043719,-0.04887504627384466,0.09320779573109034,0.48524197874422104,0.8663612864956289,0.7699015142883784,-0.9645715603540274,0.061932036437784624,0.5432894598416556,-0.001127805810301048,-0.8901609796463711,0.12431661965225804,0.48524197874422104,-0.9086735477231258,-0.6725321288961622,3.497184563628806,0.014701291299391921,-0.462815185693309,0.7420485262435965,-1.5143718566673,1.3136668502909221,-0.22738159228350283,-0.3439027766845685,1.211424359795403,0.21665972726603153,-0.11315387381905866,-0.6017771358819511,-0.032915728384741015,0.9207797152191141,-0.19451519653859392,-0.7441656379825385,-0.4972437792285436,0.8389623139505717,-0.3271128392759249,1.1985189212016558,0.5720990698697436,0.4998078409542412,1.4884520937953238,2.4309512128450095,0.9072221686279333,1.8811746612706568,2.303532579472338,-0.0648782670729416,-0.4115533912456994,0.5720990698697436,1.1073832487263275,0.12431661965225804
| 2,702
|
Dementia
| 21
| 49
| 2.744554
| 0.006059
|
P07602,Q9UBB4,Q13510,Q14108,P17900,Q9NZJ7,Q9Y487,Q5JTZ9,P20700,Q9NQZ5,P04062,O15118,P04350,O60313,P35637,P00403,O43681,P06865,P22626,P61916,Q6Y7W6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,525,26,29,162,427,41,433,309,60,188,63,449,326,203,338,467,92,354,248,516
|
1099,63,467,326,1321,785,338,188,2257,449,92,4,922,2194,162,309,1431,354,2112,2298,1903,203,1082,1876,1740,616,1969,2281,1411,2094,248,1908,1203,26,29,541,433,516,2639,1500,2468,2014,780,2659,1863,60,427,525,41
|
-0.001127805810301048,2.472830381816948,0.7140629338857863,1.014819277244463,-0.14556179771058245,0.2622891279230963,0.9747001337238531,1.549648138953408,-0.7261736594651729,0.7559915142019157,2.249632405350508,4.00405433878558,0.13980900706892938,-0.6725321288961622,1.7295441678744543,1.0810841689575286,-0.21092513401942328,0.9478015835630615,-0.6017771358819511,-0.7622139544215649,-0.4800038669191164,1.463795947164361,0.014701291299391921,-0.462815185693309,-0.377629316099032,0.48524197874422104,-0.514535240785251,-0.7441656379825385,-0.19451519653859392,-0.5842230489234069,1.3009827009421377,-0.4800038669191164,-0.0648782670729416,3.0114283478612625,3.0018786097104724,0.5864509778300103,0.7837786881907414,0.6292972508241202,-1.4937984028764713,-0.243884846085324,-0.9645715603540274,-0.5318785727630885,0.2774200528143013,-1.6393962657387167,-0.4456774203599463,2.5040493921299296,0.7976231963964028,0.6150498919054735,2.8371826720644844
| 2,702
|
Azurophil granule membrane
| 9
| 19
| 2.736764
| 0.006205
|
P07602,O95721,P11279,Q9NZJ7,P42785,O15260,Q8NF37,Q07065,P10253
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
4,353,387,427,12,109,405,179,220
|
109,1267,1321,353,4,220,387,2000,12,1969,1525,179,1281,405,519,1601,1215,427,1484
|
2.0626573264796644,-0.11315387381905866,-0.14556179771058245,0.9478015835630615,4.00405433878558,1.3892066414158972,0.8800131050184969,-0.5318785727630885,3.523552992410392,-0.514535240785251,-0.26043517265107846,1.6222608747574856,-0.11315387381905866,0.852677740649789,0.6292972508241202,-0.29367816551779385,-0.0648782670729416,0.7976231963964028,-0.22738159228350283
| 2,702
|
Abnormal retinal artery morphology
| 7
| 20
| 2.734645
| 0.006245
|
P07686,P17900,P07602,P10619,Q13510,P06865,P16278
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
160,162,4,38,26,92,93
|
900,2660,92,4,160,38,2171,93,162,207,1156,2178,1277,26,991,2444,1397,427,771,528
|
0.1552603482535626,-1.6816883017518833,2.249632405350508,4.00405433878558,1.7531245573462935,2.8665746612984697,-0.6547618971329058,2.2387939765464413,1.7295441678744543,1.4390369219353498,-0.032915728384741015,-0.6547618971329058,-0.11315387381905866,3.0114283478612625,0.09320779573109034,-0.9272458982666049,-0.17815150752877743,0.7976231963964028,0.2925118928589216,0.6150498919054735
| 2,702
|
Sterol metabolic process
| 15
| 32
| 2.732777
| 0.00628
|
O15118,Q16850,Q9UBM7,Q8WTV0,P38571,P16435,Q15392,P48449,Q15800,Q14739,Q9BQE5,Q14534,P61916,P37268,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
63,65,359,324,389,388,166,396,367,175,16,311,248,154,188
|
63,887,1174,1250,2431,188,2062,678,388,2341,154,389,2300,396,1359,2177,248,1564,2438,2555,311,175,2382,166,2043,367,65,424,324,16,359,1290
|
2.472830381816948,0.17067086843316673,-0.04887504627384466,-0.09701742595051951,-0.9272458982666049,1.549648138953408,-0.566722147958878,0.39707775152061925,0.8800131050184969,-0.8167006259673601,1.8233108238857811,0.8800131050184969,-0.7622139544215649,0.8663612864956289,-0.1618337970909173,-0.6547618971329058,1.3009827009421377,-0.27703285170862874,-0.9272458982666049,-1.1356055001499545,1.0810841689575286,1.658237345935038,-0.8533136017184143,1.705870022831379,-0.5492740993843713,0.9207797152191141,2.45192727608413,0.7976231963964028,1.0281319155612654,3.4352105279543297,0.9478015835630615,-0.11315387381905866
| 2,702
|
Glycosaminoglycan metabolism
| 7
| 12
| 2.729861
| 0.006336
|
P07686,Q8TB61,P54802,P15586,P06865,P16278,P08236
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,258,50,221,92,93,158
|
1672,282,711,92,160,158,221,93,50,1186,258,2600
|
-0.3439027766845685,1.1855852561088989,0.35249256146592,2.249632405350508,1.7531245573462935,1.7648798340833782,1.3892066414158972,2.2387939765464413,2.6577600342457113,-0.04887504627384466,1.275532592400303,-1.2722506277254433
| 2,702
|
Young adult onset
| 7
| 11
| 2.72544
| 0.006422
|
O15118,P07602,Q14566,P36551,P02545,P51649,P38435
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
63,4,296,269,241,181,86
|
63,241,4,1903,269,86,181,296,1215,1244,427
|
2.472830381816948,1.3136668502909221,4.00405433878558,-0.4800038669191164,1.224301699534718,2.303532579472338,1.6102201871058315,1.1335657467919271,-0.0648782670729416,-0.08092564237043719,0.7976231963964028
| 2,702
|
Sulfur compound transport
| 6
| 11
| 2.717427
| 0.006579
|
Q70HW3,Q8TB61,O00400,P33527,Q9H0H5,Q9UBX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,258,352,13,270,144
|
352,380,13,1159,1,258,1475,270,896,144,1805
|
0.9478015835630615,0.8936333486288025,3.497184563628806,-0.032915728384741015,4.343126506682812,1.275532592400303,-0.22738159228350283,1.224301699534718,0.17067086843316673,1.8811746612706568,-0.4115533912456994
| 2,702
|
Glycosidase
| 9
| 18
| 2.714778
| 0.006632
|
P07686,O60502,P06865,P06280,P54802,P10253,P04062,P16278,P08236
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
160,74,92,112,50,220,188,93,158
|
2672,1147,74,188,439,112,92,160,158,220,93,1061,50,605,1617,1718,478,307
|
-1.9200896765948166,-0.032915728384741015,2.378188367259261,1.549648138953408,0.7699015142883784,2.040271181152975,2.249632405350508,1.7531245573462935,1.7648798340833782,1.3892066414158972,2.2387939765464413,0.030487470396744938,2.6577600342457113,0.4998078409542412,-0.31037139890127774,-0.36074150382824394,0.700019999999374,1.0942483489073807
| 2,702
|
Vacuole organization
| 12
| 36
| 2.710175
| 0.006725
|
P07686,P11234,P50897,O75503,P11117,P54802,P10253,O14773,P16615,P04062,Q14108,Q16706
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,416,3,206,113,50,220,150,441,188,29,478
|
2148,150,1733,206,188,1229,160,220,113,416,441,1232,604,1969,720,3,1410,50,1006,1905,1594,827,29,478,1281,713,2012,780,1244,1013,486,1926,675,2577,569,1016
|
-0.6370462182791121,1.8349285964616746,-0.377629316099032,1.4514293500729303,1.549648138953408,-0.08092564237043719,1.7531245573462935,1.3892066414158972,2.040271181152975,0.8114351982042777,0.7699015142883784,-0.08092564237043719,0.4998078409542412,-0.514535240785251,0.3375549865593367,4.03639791939681,-0.19451519653859392,2.6577600342457113,0.07759089922445578,-0.4800038669191164,-0.29367816551779385,0.23190917857868676,3.0018786097104724,0.700019999999374,-0.11315387381905866,0.35249256146592,-0.5318785727630885,0.2774200528143013,-0.08092564237043719,0.07759089922445578,0.6859434192423728,-0.4800038669191164,0.41186430071853863,-1.19376905904756,0.5577119571515898,0.07759089922445578
| 2,702
|
Intrinsic component of mitochondrial inner membrane
| 11
| 30
| 2.697068
| 0.006995
|
Q6P4A7,Q99595,Q9BUR5,Q53H12,Q9Y2R0,O75431,Q15070,O14925,O75880,Q13505,Q9NX63
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
97,2,393,237,14,499,85,344,529,156,350
|
344,499,529,1151,1199,2318,2115,156,85,845,555,237,726,97,1089,1660,2427,1503,2,393,968,1629,1509,896,808,350,1117,14,783,663
|
0.9612662003264605,0.6576886443457405,0.6007678594820233,-0.032915728384741015,-0.0648782670729416,-0.7803189764195482,-0.6017771358819511,1.7883210270224281,2.314254726861213,0.21665972726603153,0.5720990698697436,1.3263238911225568,0.3375549865593367,2.217058138603211,0.014701291299391921,-0.3271128392759249,-0.9086735477231258,-0.243884846085324,4.084595663215114,0.8800131050184969,0.10878295888408213,-0.31037139890127774,-0.243884846085324,0.17067086843316673,0.24711890736266962,0.9612662003264605,-0.001127805810301048,3.497184563628806,0.2774200528143013,0.42661358757948437
| 2,702
|
Nucleobase containing compound transmembrane transporter activity
| 9
| 14
| 2.685579
| 0.00724
|
O15439,P51991,Q8TB61,O00400,P41440,P12236,Q9H2D1,Q99808,O43808
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
380,390,258,352,457,614,53,633,337
|
1319,352,380,337,860,978,614,457,390,642,258,633,53,896
|
-0.14556179771058245,0.9478015835630615,0.8936333486288025,0.9747001337238531,0.2013703373493341,0.09320779573109034,0.48524197874422104,0.7420485262435965,0.8800131050184969,0.4560011507642696,1.275532592400303,0.4706398114973275,2.5967459172501477,0.17067086843316673
| 2,702
|
Protease
| 18
| 74
| 2.680998
| 0.00734
|
Q99538,Q4J6C6,Q16740,Q9HB40,P10619,O00303,P28072,P42785,Q8TCT9,Q9H3G5,O75844,Q8TCT8,P42892,O14773,P28074,P55786,Q96K76,Q9UIQ6
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
121,66,101,6,38,138,139,12,77,18,147,118,55,150,151,28,95,64
|
138,2107,150,550,1734,147,314,877,2327,540,38,2669,1300,139,151,2506,2029,2697,1523,1304,12,55,1130,1434,1969,2478,1526,2319,2236,28,2137,165,2692,1334,2265,2652,724,101,66,295,1045,2499,2494,1134,600,118,77,659,660,1536,522,2599,95,1285,1504,791,585,2659,121,764,537,18,2269,1480,6,332,932,2129,250,1142,64,588,783,2230
|
1.904163939767927,-0.6017771358819511,1.8349285964616746,0.5720990698697436,-0.377629316099032,1.858096452664984,1.0546674241385827,0.18604079096340007,-0.7984810752691569,0.5864509778300103,2.8665746612984697,-1.7457215321911723,-0.12933524422973913,1.904163939767927,1.8349285964616746,-1.0399582580540272,-0.5492740993843713,-6.251142318365236,-0.26043517265107846,-0.12933524422973913,3.523552992410392,2.5660054539144865,-0.017000063987738737,-0.21092513401942328,-0.514535240785251,-0.983325689072196,-0.26043517265107846,-0.7803189764195482,-0.7082376548394596,3.0018786097104724,-0.6193847456466299,1.717718863168589,-4.69941189821712,-0.14556179771058245,-0.7261736594651729,-1.5765412690495015,0.3375549865593367,2.1623710072700724,2.441448397195739,1.1466136121023172,0.04623097246479662,-1.0210186165202892,-1.0021412347204408,-0.017000063987738737,0.5143375851029162,2.0065339889232616,2.3569527332268905,0.42661358757948437,0.42661358757948437,-0.26043517265107846,0.6150498919054735,-1.2722506277254433,2.2279359123064713,-0.11315387381905866,-0.243884846085324,0.2622891279230963,0.5288313967073893,-1.6393962657387167,1.9952458014491112,0.2925118928589216,0.6007678594820233,3.2820201142446788,-0.7261736594651729,-0.22738159228350283,3.9059864908023467,1.0014765288625636,0.13980900706892938,-0.6017771358819511,1.3009827009421377,-0.017000063987738737,2.472830381816948,0.5288313967073893,0.2774200528143013,-0.6903572636353332
| 2,702
|
Carbohydrate derivative transport
| 11
| 18
| 2.678394
| 0.007398
|
O15439,Q8TB61,O00400,P07602,Q8WTV0,Q9NZJ7,P41440,P12236,O43808,Q99808,P61916
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
380,258,352,4,324,427,457,614,337,633,248
|
1319,352,380,337,860,4,978,614,457,248,757,642,258,1475,324,633,896,427
|
-0.14556179771058245,0.9478015835630615,0.8936333486288025,0.9747001337238531,0.2013703373493341,4.00405433878558,0.09320779573109034,0.48524197874422104,0.7420485262435965,1.3009827009421377,0.2925118928589216,0.4560011507642696,1.275532592400303,-0.22738159228350283,1.0281319155612654,0.4706398114973275,0.17067086843316673,0.7976231963964028
| 2,702
|
Abnormal muscle fiber morphology
| 21
| 57
| 2.672102
| 0.007538
|
Q70HW3,Q99720,O95831,O43676,P51114,Q86U42,Q9BPX6,Q9H2D1,P07196,P06753,O60313,P35637,P00403,P22626,Q9Y5P6,P50402,P23786,P61978,P02545,Q7Z406,O14979
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,5,9,20,276,412,303,53,185,440,326,203,338,354,497,233,105,243,241,383,251
|
1586,251,20,1873,326,2326,627,9,785,338,241,2650,440,185,2417,922,978,2505,354,105,2298,1903,203,2329,616,1969,233,755,276,2002,2094,243,1528,2160,1257,1769,1795,2424,651,1,1532,383,412,2292,506,5,303,806,1538,1191,53,2665,1758,2416,783,1634,497
|
-0.29367816551779385,1.2882713222080582,3.1993280187186217,-0.462815185693309,1.014819277244463,-0.7984810752691569,0.4706398114973275,3.601980510099323,0.2622891279230963,0.9747001337238531,1.3136668502909221,-1.5765412690495015,0.7699015142883784,1.586065401491409,-0.9086735477231258,0.13980900706892938,0.09320779573109034,-1.0399582580540272,0.9478015835630615,2.096080199744481,-0.7622139544215649,-0.4800038669191164,1.463795947164361,-0.7984810752691569,0.48524197874422104,-0.514535240785251,1.338953943492325,0.2925118928589216,1.1985189212016558,-0.5318785727630885,-0.5842230489234069,1.3136668502909221,-0.26043517265107846,-0.6370462182791121,-0.09701742595051951,-0.3945665116133365,-0.4115533912456994,-0.9086735477231258,0.4413258066063131,4.343126506682812,-0.26043517265107846,0.8936333486288025,0.8252148517366122,-0.7441656379825385,0.6435101106197167,4.00405433878558,1.1073832487263275,0.24711890736266962,-0.26043517265107846,-0.04887504627384466,2.5967459172501477,-1.7029527383730034,-0.377629316099032,-0.8901609796463711,0.2774200528143013,-0.31037139890127774,0.6718330237408522
| 2,702
|
Golgi apparatus
| 45
| 143
| 2.667592
| 0.00764
|
Q5BKZ1,O15439,P50897,A4D1U4,Q9HB40,P80303,O95070,Q8N4Q0,P24390,Q8IZA0,Q8NEW0,Q9H2V7,O00231,Q9NPR9,Q9HD45,Q5VW38,P11717,Q14789,Q5KU26,Q6NT16,P67812,O75955,O60637,O75122,Q92896,Q8TD16,Q8IXU6,A1L0T0,Q9NX62,O15127,Q9UBU6,P09601,O43760,Q93050,Q9NWM8,P16278,Q16706,Q96C57,Q8NBN3,O15212,Q02818,O15260,O14976,Q8NC54,O00461
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
255,380,3,259,6,135,386,140,15,278,152,153,274,155,285,30,417,418,163,37,165,422,49,430,183,313,61,448,454,325,205,334,81,82,91,93,478,480,108,231,236,109,110,491,126
|
448,259,2606,2148,274,126,710,638,110,1759,325,231,1453,109,816,380,1222,1122,1810,81,1732,49,1490,1674,430,2404,422,386,888,2487,2533,334,1900,2564,417,93,1555,15,1932,2172,2476,1156,1234,1355,1819,2434,1741,1460,701,1969,983,755,720,3,2583,984,822,2156,2376,165,135,1278,565,236,2694,1062,1494,532,1747,1184,418,2120,478,255,163,2222,30,2206,1281,37,963,542,802,1107,2539,1691,505,2413,1828,2384,1773,713,1210,61,2124,278,1339,140,738,108,491,152,313,1620,1475,929,183,2348,82,621,777,480,622,2141,2047,2684,766,1698,153,1094,2269,949,2627,6,538,285,155,2208,1033,1580,875,91,454,883,205,1117,1844,568,1730,885,1988,2106,936
|
0.7559915142019157,1.2627663890027823,-1.311898640240956,-0.6370462182791121,1.1985189212016558,1.9726052400824703,0.35249256146592,0.4560011507642696,2.051474730794449,-0.3945665116133365,1.014819277244463,1.338953943492325,-0.22738159228350283,2.0626573264796644,0.23190917857868676,0.8936333486288025,-0.08092564237043719,-0.017000063987738737,-0.4285902586631195,2.3356417057869807,-0.377629316099032,2.6577600342457113,-0.243884846085324,-0.3439027766845685,0.7837786881907414,-0.8901609796463711,0.7976231963964028,0.8800131050184969,0.17067086843316673,-1.0021412347204408,-1.0971550435827746,0.9881035286247505,-0.4800038669191164,-1.174315546728808,0.8114351982042777,2.2387939765464413,-0.27703285170862874,3.4883696583674233,-0.4972437792285436,-0.6547618971329058,-0.983325689072196,-0.032915728384741015,-0.08092564237043719,-0.1618337970909173,-0.4285902586631195,-0.9272458982666049,-0.377629316099032,-0.22738159228350283,0.3673920803157548,-0.514535240785251,0.09320779573109034,0.2925118928589216,0.3375549865593367,4.03639791939681,-1.2132888500172512,0.09320779573109034,0.23190917857868676,-0.6370462182791121,-0.8533136017184143,1.717718863168589,1.9270649969621256,-0.11315387381905866,0.5577119571515898,1.3263238911225568,-5.875733142878054,0.030487470396744938,-0.243884846085324,0.6007678594820233,-0.377629316099032,-0.04887504627384466,0.8114351982042777,-0.6017771358819511,0.700019999999374,1.2882713222080582,1.7295441678744543,-0.6903572636353332,2.9923137792580112,-0.6725321288961622,-0.11315387381905866,2.886090180376803,0.10878295888408213,0.5864509778300103,0.24711890736266962,-0.001127805810301048,-1.0971550435827746,-0.3439027766845685,0.6435101106197167,-0.8901609796463711,-0.4285902586631195,-0.8533136017184143,-0.3945665116133365,0.35249256146592,-0.0648782670729416,2.4832547399290448,-0.6017771358819511,1.1985189212016558,-0.14556179771058245,1.8926803722806396,0.32257915315367963,2.0849599804357837,0.6718330237408522,1.8349285964616746,1.0678905729851498,-0.31037139890127774,-0.22738159228350283,0.13980900706892938,1.598155063758245,-0.8167006259673601,2.3356417057869807,0.48524197874422104,0.2774200528143013,0.700019999999374,0.48524197874422104,-0.6193847456466299,-0.5492740993843713,-2.1921262614398054,0.2925118928589216,-0.3439027766845685,1.8349285964616746,0.014701291299391921,-0.7261736594651729,0.12431661965225804,-1.4122382294877622,3.9059864908023467,0.6007678594820233,1.1855852561088989,1.8233108238857811,-0.6725321288961622,0.061932036437784624,-0.27703285170862874,0.2013703373493341,2.260451272324659,0.7559915142019157,0.18604079096340007,1.463795947164361,-0.001127805810301048,-0.4285902586631195,0.5577119571515898,-0.36074150382824394,0.18604079096340007,-0.514535240785251,-0.5842230489234069,0.13980900706892938
| 2,702
|
Nuclear envelope ne reassembly
| 17
| 49
| 2.660111
| 0.007811
|
P04350,Q8NFH4,Q13885,P37198,Q86XL3,P50402,Q7Z3B4,Q9BTX1,Q9BVA1,Q14739,Q8N1F7,Q92973,P02545,P20700,P68371,Q12769,O43633
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
449,291,357,133,102,233,557,202,466,175,238,434,241,309,216,566,501
|
501,2353,1610,241,449,1080,1642,2026,309,1179,133,1433,648,2001,233,1526,1157,985,658,1766,866,216,566,357,175,1010,1044,557,102,870,1111,238,291,739,928,1394,1395,705,434,804,1837,202,850,466,1050,1000,1926,581,1016
|
0.6435101106197167,-0.8349780072652183,-0.31037139890127774,1.3136668502909221,0.7559915142019157,0.014701291299391921,-0.3271128392759249,-0.5492740993843713,1.0810841689575286,-0.04887504627384466,1.9384826617323367,-0.21092513401942328,0.4413258066063131,-0.5318785727630885,1.338953943492325,-0.26043517265107846,-0.032915728384741015,0.09320779573109034,0.42661358757948437,-0.3945665116133365,0.2013703373493341,1.4017035243632918,0.5577119571515898,0.9478015835630615,1.658237345935038,0.07759089922445578,0.04623097246479662,0.5720990698697436,2.1623710072700724,0.2013703373493341,-0.001127805810301048,1.3263238911225568,1.1596327314267856,0.32257915315367963,0.13980900706892938,-0.17815150752877743,-0.17815150752877743,0.3673920803157548,0.7837786881907414,0.24711890736266962,-0.4285902586631195,1.4761368247888418,0.21665972726603153,0.7280723875131836,0.04623097246479662,0.09320779573109034,-0.4800038669191164,0.5432894598416556,0.07759089922445578
| 2,702
|
Pain
| 36
| 146
| 2.656723
| 0.00789
|
Q70HW3,P07602,Q03252,P36551,Q96HY6,O75844,Q13510,Q14108,O15269,P07686,Q8NFH4,Q14566,Q14739,P20700,P42892,P04062,P31749,Q92804,O15460,O60313,P35637,Q9NR77,P21964,Q15165,P28070,P22626,P23786,P50402,Q9NZ08,Q8N1F7,Q15800,P06280,P02545,Q13423,P14174,Q01844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,4,391,269,272,147,26,29,415,160,291,296,175,309,55,188,189,194,195,326,203,78,207,94,355,354,105,233,250,238,367,112,241,119,122,253
|
1219,1099,1548,456,415,1454,195,582,2660,326,887,817,147,1249,1735,2486,1079,241,188,2650,1198,112,1429,4,160,1898,2150,922,1154,1519,2611,2062,978,122,1127,1021,2524,1176,309,1233,1431,207,1554,2505,354,105,1998,355,2298,2234,189,840,1156,203,269,2433,1935,2629,1739,55,616,879,924,511,1182,1359,233,755,630,1463,2175,984,2376,756,2178,1411,2094,2377,658,2217,2345,1277,565,1468,253,1159,391,1746,1973,1331,566,2037,749,1203,1361,119,26,1257,29,541,1795,296,1718,175,926,789,991,94,1209,367,2398,2267,1108,1,1532,238,1367,727,291,928,2468,1693,506,705,2444,194,1397,706,272,805,1863,1538,1191,1000,1140,1373,78,250,427,2470,674,2187,771,581,528,1703
|
-0.08092564237043719,-0.001127805810301048,-0.27703285170862874,0.7420485262435965,0.8114351982042777,-0.22738159228350283,1.500741864308918,0.5288313967073893,-1.6816883017518833,1.014819277244463,0.17067086843316673,0.23190917857868676,1.858096452664984,-0.09701742595051951,-0.377629316099032,-1.0021412347204408,0.014701291299391921,1.3136668502909221,1.549648138953408,-1.5765412690495015,-0.0648782670729416,2.040271181152975,-0.21092513401942328,4.00405433878558,1.7531245573462935,-0.4800038669191164,-0.6370462182791121,0.13980900706892938,-0.032915728384741015,-0.26043517265107846,-1.331826169509489,-0.566722147958878,0.09320779573109034,1.983936246561302,-0.017000063987738737,0.061932036437784624,-1.07802603682358,-0.04887504627384466,1.0810841689575286,-0.08092564237043719,-0.21092513401942328,1.4390369219353498,-0.27703285170862874,-1.0399582580540272,0.9478015835630615,2.096080199744481,-0.5318785727630885,0.9478015835630615,-0.7622139544215649,-0.7082376548394596,1.549648138953408,0.21665972726603153,-0.032915728384741015,1.463795947164361,1.224301699534718,-0.9272458982666049,-0.4972437792285436,-1.4325193129919627,-0.377629316099032,2.5660054539144865,0.48524197874422104,0.18604079096340007,0.13980900706892938,0.6292972508241202,-0.04887504627384466,-0.1618337970909173,1.338953943492325,0.2925118928589216,0.4706398114973275,-0.22738159228350283,-0.6547618971329058,0.09320779573109034,-0.8533136017184143,0.2925118928589216,-0.6547618971329058,-0.19451519653859392,-0.5842230489234069,-0.8533136017184143,0.42661358757948437,-0.6903572636353332,-0.8167006259673601,-0.11315387381905866,0.5577119571515898,-0.22738159228350283,1.2882713222080582,-0.032915728384741015,0.8800131050184969,-0.377629316099032,-0.514535240785251,-0.14556179771058245,0.5577119571515898,-0.5492740993843713,0.30756485716682186,-0.0648782670729416,-0.1618337970909173,1.9952458014491112,3.0114283478612625,-0.09701742595051951,3.0018786097104724,0.5864509778300103,-0.4115533912456994,1.1335657467919271,-0.36074150382824394,1.658237345935038,0.13980900706892938,0.2622891279230963,0.09320779573109034,2.2387939765464413,-0.0648782670729416,0.9207797152191141,-0.8717077957387307,-0.7261736594651729,-0.001127805810301048,4.343126506682812,-0.26043517265107846,1.3263238911225568,-0.1618337970909173,0.3375549865593367,1.1596327314267856,0.13980900706892938,-0.9645715603540274,-0.3439027766845685,0.6435101106197167,0.3673920803157548,-0.9272458982666049,1.5130062457371627,-0.17815150752877743,0.3673920803157548,1.211424359795403,0.24711890736266962,-0.4456774203599463,-0.26043517265107846,-0.04887504627384466,0.09320779573109034,-0.017000063987738737,-0.1618337970909173,2.3569527332268905,1.3009827009421377,0.7976231963964028,-0.9645715603540274,0.41186430071853863,-0.6547618971329058,0.2925118928589216,0.5432894598416556,0.6150498919054735,-0.3439027766845685
| 2,702
|
Abnormality of the lymphatic system
| 36
| 121
| 2.656475
| 0.007896
|
P07602,P38571,P36551,Q10713,Q96HY6,Q13510,P00813,Q14108,P08236,P07686,Q9UJS0,P10619,Q15392,Q9NZJ7,P33991,Q14739,P54802,Q96A33,O96028,P04062,P31749,P04066,O15118,O15460,P21964,Q9Y3Z3,P10253,P16278,P15586,P28070,Q9NZ08,O95202,P02545,P61916,P14174,Q01844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,389,269,397,272,26,27,29,158,160,420,38,166,427,42,175,50,442,187,188,189,439,63,195,207,342,220,93,221,355,250,363,241,248,122,253
|
2148,2190,2672,2516,456,63,195,1811,2550,817,1249,2579,363,2024,187,2563,27,241,188,439,2650,1198,2475,1429,4,160,158,1963,220,38,1154,889,1519,2258,1350,2062,1816,2669,122,221,93,1081,2196,1101,1233,207,1554,1998,355,615,2029,189,42,2651,1522,269,1591,389,1935,2452,1968,924,511,1182,679,983,720,2583,1593,1463,2178,2071,50,1937,1102,2630,2283,248,253,1746,397,749,1361,2117,1942,26,1617,29,175,2652,926,166,1064,2510,1209,488,542,1690,1108,2165,727,1693,2444,1397,442,272,1779,2385,805,1215,874,1097,1919,250,427,2167,420,1956,581,342,1704
|
-0.6370462182791121,-0.6725321288961622,-1.9200896765948166,-1.0589605873257606,0.7420485262435965,2.472830381816948,1.500741864308918,-0.4285902586631195,-1.1356055001499545,0.23190917857868676,-0.09701742595051951,-1.2132888500172512,0.9207797152191141,-0.5492740993843713,1.561812043982834,-1.174315546728808,3.0018786097104724,1.3136668502909221,1.549648138953408,0.7699015142883784,-1.5765412690495015,-0.0648782670729416,-0.983325689072196,-0.21092513401942328,4.00405433878558,1.7531245573462935,1.7648798340833782,-0.514535240785251,1.3892066414158972,2.8665746612984697,-0.032915728384741015,0.17067086843316673,-0.26043517265107846,-0.7261736594651729,-0.1618337970909173,-0.566722147958878,-0.4285902586631195,-1.7457215321911723,1.983936246561302,1.3892066414158972,2.2387939765464413,0.014701291299391921,-0.6725321288961622,-0.001127805810301048,-0.08092564237043719,1.4390369219353498,-0.27703285170862874,-0.5318785727630885,0.9478015835630615,0.48524197874422104,-0.5492740993843713,1.549648138953408,2.7878758792557337,-1.5765412690495015,-0.26043517265107846,1.224301699534718,-0.29367816551779385,0.8800131050184969,-0.4972437792285436,-0.9458784336451688,-0.514535240785251,0.13980900706892938,0.6292972508241202,-0.04887504627384466,0.39707775152061925,0.09320779573109034,0.3375549865593367,-1.2132888500172512,-0.29367816551779385,-0.22738159228350283,-0.6547618971329058,-0.566722147958878,2.6577600342457113,-0.4972437792285436,-0.001127805810301048,-1.4325193129919627,-0.7441656379825385,1.3009827009421377,1.2882713222080582,-0.377629316099032,0.8663612864956289,0.30756485716682186,-0.1618337970909173,-0.6017771358819511,-0.4972437792285436,3.0114283478612625,-0.31037139890127774,3.0018786097104724,1.658237345935038,-1.5765412690495015,0.13980900706892938,1.705870022831379,0.030487470396744938,-1.0399582580540272,-0.0648782670729416,0.6718330237408522,0.5864509778300103,-0.3439027766845685,-0.001127805810301048,-0.6370462182791121,0.3375549865593367,-0.3439027766845685,-0.9272458982666049,-0.17815150752877743,0.7699015142883784,1.211424359795403,-0.3945665116133365,-0.8533136017184143,0.24711890736266962,-0.0648782670729416,0.2013703373493341,0.014701291299391921,-0.4800038669191164,1.3009827009421377,0.7976231963964028,-0.6370462182791121,0.8114351982042777,-0.4972437792285436,0.5432894598416556,0.9747001337238531,-0.3439027766845685
| 2,702
|
Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]
| 52
| 121
| 2.654043
| 0.007953
|
P51991,P23588,Q8WUA2,P52597,Q99729,Q9UHX1,Q9P2N5,Q15233,Q86U42,P26368,Q9P2K5,Q12849,P31942,Q01085,Q8N684,Q13595,Q9Y2U8,Q13242,Q86V81,Q92804,P78332,P98175,P07910,Q07955,P35637,Q14103,P23246,Q96PK6,Q15287,P38159,Q8WXF1,P62995,Q16629,Q13151,Q8IXT5,O43390,Q9BY77,P52272,P98179,O60506,P22626,Q9BWF3,Q9Y6M1,O75494,Q13247,P43243,Q16540,P31943,P55795,Q01844,Q53F19,O14979
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
390,510,264,266,268,141,524,403,412,666,429,681,168,552,696,693,581,318,704,194,702,322,450,453,203,464,335,336,597,212,473,339,607,723,737,219,740,476,224,227,354,493,498,361,617,616,489,247,382,253,124,251
|
1424,971,251,1220,1266,219,1872,227,361,2059,2024,1709,450,1153,1640,1518,922,773,786,1457,1231,354,335,510,666,1432,1903,168,247,1645,203,212,2374,616,1524,390,476,266,1040,382,2216,2411,339,702,907,322,224,552,253,2678,453,1083,681,1203,723,318,962,617,2038,1042,693,464,1363,1529,2004,2122,991,403,597,1106,1208,944,489,607,1770,124,1306,1418,412,704,737,1310,1692,696,1090,739,264,2540,473,1832,194,1066,1167,966,336,915,2385,268,493,740,1783,2294,1865,794,1483,1668,2102,851,429,524,1513,141,1514,884,1485,1344,581,1633,1173,1704,498
|
-0.21092513401942328,0.09320779573109034,1.2882713222080582,-0.08092564237043719,-0.11315387381905866,1.3892066414158972,-0.462815185693309,1.364133559046907,0.9343061375179438,-0.566722147958878,-0.5492740993843713,-0.36074150382824394,0.7559915142019157,-0.032915728384741015,-0.3271128392759249,-0.26043517265107846,0.13980900706892938,0.2774200528143013,0.2622891279230963,-0.22738159228350283,-0.08092564237043719,0.9478015835630615,0.9881035286247505,0.6292972508241202,0.41186430071853863,-0.21092513401942328,-0.4800038669191164,1.6701813099617207,1.3009827009421377,-0.3271128392759249,1.463795947164361,1.4141741225146764,-0.8533136017184143,0.48524197874422104,-0.26043517265107846,0.8800131050184969,0.700019999999374,1.237151067189716,0.04623097246479662,0.8936333486288025,-0.6903572636353332,-0.8901609796463711,0.9747001337238531,0.3673920803157548,0.1552603482535626,1.0281319155612654,1.3766833583434828,0.5720990698697436,1.2882713222080582,-2.0093246694096405,0.7559915142019157,0.014701291299391921,0.39707775152061925,-0.0648782670729416,0.3375549865593367,1.0414145845970093,0.10878295888408213,0.48524197874422104,-0.5492740993843713,0.04623097246479662,0.382253743928895,0.7280723875131836,-0.1618337970909173,-0.26043517265107846,-0.5318785727630885,-0.6017771358819511,0.09320779573109034,0.852677740649789,0.5143375851029162,-0.001127805810301048,-0.0648782670729416,0.12431661965225804,0.6718330237408522,0.4998078409542412,-0.3945665116133365,1.983936246561302,-0.12933524422973913,-0.19451519653859392,0.8252148517366122,0.3673920803157548,0.32257915315367963,-0.12933524422973913,-0.3439027766845685,0.382253743928895,0.014701291299391921,0.32257915315367963,1.249972588664049,-1.0971550435827746,0.7140629338857863,-0.4285902586631195,1.5130062457371627,0.030487470396744938,-0.032915728384741015,0.10878295888408213,0.9881035286247505,0.1552603482535626,-0.8533136017184143,1.237151067189716,0.6718330237408522,0.32257915315367963,-0.3945665116133365,-0.7441656379825385,-0.4456774203599463,0.2622891279230963,-0.22738159228350283,-0.3271128392759249,-0.5842230489234069,0.21665972726603153,0.7976231963964028,0.6150498919054735,-0.243884846085324,1.8926803722806396,-0.243884846085324,0.18604079096340007,-0.22738159228350283,-0.14556179771058245,0.5432894598416556,-0.31037139890127774,-0.032915728384741015,-0.3439027766845685,0.6718330237408522
| 2,702
|
Sensorimotor neuropathy
| 12
| 29
| 2.642752
| 0.008224
|
Q5KU26,P07602,O60313,Q15120,Q9NZJ7,O95831,Q8N2K0,P41440,Q9Y2R0,Q9NR77,P00403,P07196
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
163,4,326,327,427,9,425,457,14,78,338,185
|
1099,1454,326,9,338,539,185,4,2449,1738,2645,1739,457,1649,1593,2094,2377,1857,463,327,163,425,1284,1775,78,796,427,14,783
|
-0.001127805810301048,-0.22738159228350283,1.014819277244463,3.601980510099323,0.9747001337238531,0.5864509778300103,1.586065401491409,4.00405433878558,-0.9458784336451688,-0.377629316099032,-1.5350197765489455,-0.377629316099032,0.7420485262435965,-0.3271128392759249,-0.29367816551779385,-0.5842230489234069,-0.8533136017184143,-0.4456774203599463,0.7280723875131836,1.014819277244463,1.7295441678744543,0.7976231963964028,-0.11315387381905866,-0.3945665116133365,2.3569527332268905,0.2622891279230963,0.7976231963964028,3.497184563628806,0.2774200528143013
| 2,702
|
Tetrapyrrole metabolic process
| 8
| 16
| 2.642536
| 0.008229
|
P30536,P30519,P22830,P33527,P09601,P36551,O75027,O00264
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
289,35,7,13,334,269,312,159
|
159,312,334,7,1178,35,289,13,269,1743,1657,409,1371,632,2666,1375
|
1.7531245573462935,1.0678905729851498,0.9881035286247505,3.7135134684721347,-0.04887504627384466,2.915245805395765,1.1596327314267856,3.497184563628806,1.224301699534718,-0.377629316099032,-0.3271128392759249,0.8389623139505717,-0.1618337970909173,0.4706398114973275,-1.7029527383730034,-0.1618337970909173
| 2,702
|
Abnormality of the upper respiratory tract
| 23
| 84
| 2.636937
| 0.008366
|
P07602,P16435,Q9UHX1,Q96HY6,Q13510,P00813,P08236,Q86U42,Q9NZJ7,Q14739,P54802,Q9BV10,Q92804,O15460,P35637,P21964,Q13432,P15586,P16278,Q15165,Q9UBM7,P28070,P02545
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,388,141,272,26,27,158,412,427,175,50,320,194,195,203,207,214,221,93,94,359,355,241
|
839,2672,1487,1548,816,195,1811,1674,2404,1735,2024,2563,27,241,439,1198,1429,4,1898,158,922,1154,221,93,388,2407,1233,207,1612,355,878,203,1082,1523,1024,1935,1968,616,879,924,720,630,1462,984,2178,50,2094,2345,565,2037,1203,1942,214,26,541,175,1858,94,1208,2617,751,2123,412,2165,2100,1619,2444,1445,194,1397,1536,1599,706,1476,272,1863,320,1215,1951,1097,427,2167,359,141
|
0.21665972726603153,-1.9200896765948166,-0.243884846085324,-0.27703285170862874,0.23190917857868676,1.500741864308918,-0.4285902586631195,-0.3439027766845685,-0.8901609796463711,-0.377629316099032,-0.5492740993843713,-1.174315546728808,3.0018786097104724,1.3136668502909221,0.7699015142883784,-0.0648782670729416,-0.21092513401942328,4.00405433878558,-0.4800038669191164,1.7648798340833782,0.13980900706892938,-0.032915728384741015,1.3892066414158972,2.2387939765464413,0.8800131050184969,-0.8901609796463711,-0.08092564237043719,1.4390369219353498,-0.31037139890127774,0.9478015835630615,0.18604079096340007,1.463795947164361,0.014701291299391921,-0.26043517265107846,0.061932036437784624,-0.4972437792285436,-0.514535240785251,0.48524197874422104,0.18604079096340007,0.13980900706892938,0.3375549865593367,0.4706398114973275,-0.22738159228350283,0.09320779573109034,-0.6547618971329058,2.6577600342457113,-0.5842230489234069,-0.8167006259673601,0.5577119571515898,-0.5492740993843713,-0.0648782670729416,-0.4972437792285436,1.4141741225146764,3.0114283478612625,0.5864509778300103,1.658237345935038,-0.4456774203599463,2.2387939765464413,-0.0648782670729416,-1.3518233822249164,0.30756485716682186,-0.6017771358819511,0.8252148517366122,-0.6370462182791121,-0.5842230489234069,-0.31037139890127774,-0.9272458982666049,-0.21092513401942328,1.5130062457371627,-0.17815150752877743,-0.26043517265107846,-0.29367816551779385,0.3673920803157548,-0.22738159228350283,1.211424359795403,-0.4456774203599463,1.0414145845970093,-0.0648782670729416,-0.4972437792285436,0.014701291299391921,0.7976231963964028,-0.6370462182791121,0.9478015835630615,1.8926803722806396
| 2,702
|
Steroid biosynthesis
| 7
| 10
| 2.634682
| 0.008422
|
Q16850,Q9UBM7,P38571,Q15392,Q15800,Q14534,P37268
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
65,359,389,166,367,311,154
|
1174,154,389,396,311,166,2043,367,65,359
|
-0.04887504627384466,1.8233108238857811,0.8800131050184969,0.8663612864956289,1.0810841689575286,1.705870022831379,-0.5492740993843713,0.9207797152191141,2.45192727608413,0.9478015835630615
| 2,702
|
Abnormality of the ribs
| 19
| 57
| 2.620907
| 0.00877
|
P16435,O95831,Q9UHX1,Q96HY6,O75844,P00813,Q14739,P54802,O96028,Q9BV10,Q7Z4L5,P16278,P15586,Q32P28,Q9Y619,Q9UBM7,O95202,P02545,Q03164
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
388,9,141,272,147,27,175,50,187,320,71,93,221,225,226,359,363,241,123
|
2672,1548,2404,385,499,2353,562,147,2579,363,9,187,27,241,718,221,93,388,1996,1101,2407,2505,2535,2489,982,1409,755,1463,50,2345,1882,1528,123,1746,1715,827,2117,175,1208,2043,2044,2097,225,1417,1912,2413,71,2100,272,2385,320,2167,359,141,1376,1704,226
|
-1.9200896765948166,-0.27703285170862874,-0.8901609796463711,0.8800131050184969,0.6576886443457405,-0.8349780072652183,0.5577119571515898,1.858096452664984,-1.2132888500172512,0.9207797152191141,3.601980510099323,1.561812043982834,3.0018786097104724,1.3136668502909221,0.3375549865593367,1.3892066414158972,2.2387939765464413,0.8800131050184969,-0.5318785727630885,-0.001127805810301048,-0.8901609796463711,-1.0399582580540272,-1.0971550435827746,-1.0021412347204408,0.09320779573109034,-0.19451519653859392,0.2925118928589216,-0.22738159228350283,2.6577600342457113,-0.8167006259673601,-0.462815185693309,-0.26043517265107846,1.983936246561302,-0.377629316099032,-0.36074150382824394,0.23190917857868676,-0.6017771358819511,1.658237345935038,-0.0648782670729416,-0.5492740993843713,-0.5492740993843713,-0.5842230489234069,1.3766833583434828,-0.19451519653859392,-0.4800038669191164,-0.8901609796463711,2.420435656490256,-0.5842230489234069,1.211424359795403,-0.8533136017184143,1.0414145845970093,-0.6370462182791121,0.9478015835630615,1.8926803722806396,-0.1618337970909173,-0.3439027766845685,1.3766833583434828
| 2,702
|
Endoplasmic reticulum golgi intermediate compartment membrane
| 9
| 19
| 2.613184
| 0.00897
|
O95070,O15260,P24390,Q15904,Q13190,P51572,Q9Y3B3,Q9Y282,Q15363
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
386,109,15,488,532,469,130,62,372
|
109,1121,1733,386,15,1998,1327,701,469,823,554,1133,532,372,488,752,62,1119,130
|
2.0626573264796644,-0.017000063987738737,-0.377629316099032,0.8800131050184969,3.4883696583674233,-0.5318785727630885,-0.14556179771058245,0.3673920803157548,0.7140629338857863,0.23190917857868676,0.5720990698697436,-0.017000063987738737,0.6007678594820233,0.9072221686279333,0.6718330237408522,0.30756485716682186,2.4832547399290448,-0.001127805810301048,1.9612526973306057
| 2,702
|
Proximal muscle weakness
| 20
| 50
| 2.613182
| 0.00897
|
Q99720,P36551,Q9BQT8,P51114,Q13126,Q13510,Q86U42,Q9BPX6,Q8TD16,P07196,P06753,O60313,P35637,P10253,Q8TB36,P22626,Q9Y5P6,P50402,P02545,Q7Z406
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
5,269,146,276,24,26,412,303,313,185,440,326,203,220,484,354,497,233,241,383
|
326,2326,1735,241,2447,440,185,922,220,2611,978,1874,2196,1431,2505,354,2298,203,269,2645,233,755,276,2094,735,2160,24,1203,26,1257,1769,1795,893,641,1532,383,412,946,484,313,506,1284,5,303,146,1538,1191,2416,497,954
|
1.014819277244463,-0.7984810752691569,-0.377629316099032,1.3136668502909221,-0.9458784336451688,0.7699015142883784,1.586065401491409,0.13980900706892938,1.3892066414158972,-1.331826169509489,0.09320779573109034,-0.462815185693309,-0.6725321288961622,-0.21092513401942328,-1.0399582580540272,0.9478015835630615,-0.7622139544215649,1.463795947164361,1.224301699534718,-1.5350197765489455,1.338953943492325,0.2925118928589216,1.1985189212016558,-0.5842230489234069,0.32257915315367963,-0.6370462182791121,3.0778580474948067,-0.0648782670729416,3.0114283478612625,-0.09701742595051951,-0.3945665116133365,-0.4115533912456994,0.17067086843316673,0.4560011507642696,-0.26043517265107846,0.8936333486288025,0.8252148517366122,0.12431661965225804,0.6859434192423728,1.0678905729851498,0.6435101106197167,-0.11315387381905866,4.00405433878558,1.1073832487263275,1.8696467178692489,-0.26043517265107846,-0.04887504627384466,-0.8901609796463711,0.6718330237408522,0.12431661965225804
| 2,702
|
Aminoglycan metabolic process
| 8
| 13
| 2.612155
| 0.008997
|
P07686,P04066,P54802,P15586,O43505,P06865,P16278,P08236
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,439,50,221,282,92,93,158
|
282,2255,1961,439,92,160,158,221,93,50,2035,1186,454
|
1.1855852561088989,-0.7261736594651729,-0.514535240785251,0.7699015142883784,2.249632405350508,1.7531245573462935,1.7648798340833782,1.3892066414158972,2.2387939765464413,2.6577600342457113,-0.5492740993843713,-0.04887504627384466,0.7559915142019157
| 2,702
|
Atpase coupled transmembrane transporter activity
| 10
| 22
| 2.60804
| 0.009106
|
O15439,P05023,Q9HD20,Q9Y5K8,P33527,Q15388,P08183,O75027,P06576,P16615
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
380,539,69,561,13,366,54,312,215,441
|
380,312,539,1252,215,54,441,1022,1101,2406,941,615,13,1082,1876,1463,841,1278,366,69,1217,561
|
0.8936333486288025,1.0678905729851498,0.5864509778300103,-0.09701742595051951,1.4017035243632918,2.5762697271805473,0.7699015142883784,0.061932036437784624,-0.001127805810301048,-0.8901609796463711,0.12431661965225804,0.48524197874422104,3.497184563628806,0.014701291299391921,-0.462815185693309,-0.22738159228350283,0.21665972726603153,-0.11315387381905866,0.9207797152191141,2.4309512128450095,-0.0648782670729416,0.5720990698697436
| 2,702
|
Intermediate filament, rod domain [IPR039008]
| 7
| 8
| 2.605278
| 0.00918
|
P07196,Q03252,Q16352,P07197,P02545,P20700,P08670
|
Sequence
|
InterPro Domain
|
interpro_domain
|
185,391,234,305,241,309,89
|
241,185,305,89,309,468,391,234
|
1.3136668502909221,1.586065401491409,1.0942483489073807,2.282030613119506,1.0810841689575286,0.7140629338857863,0.8800131050184969,1.338953943492325
| 2,702
|
Intermediate filament protein, conserved site [IPR018039]
| 7
| 8
| 2.605278
| 0.00918
|
P07196,Q03252,Q16352,P07197,P02545,P20700,P08670
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
185,391,234,305,241,309,89
|
241,185,305,89,309,468,391,234
|
1.3136668502909221,1.586065401491409,1.0942483489073807,2.282030613119506,1.0810841689575286,0.7140629338857863,0.8800131050184969,1.338953943492325
| 2,702
|
Abnormal rib cage morphology
| 21
| 66
| 2.602373
| 0.009258
|
P16435,O95831,Q9UHX1,Q96HY6,O75844,P00813,P08236,Q14739,P54802,O96028,P31749,Q9BV10,Q7Z4L5,P16278,P15586,Q32P28,Q9Y619,Q9UBM7,O95202,P02545,Q03164
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
388,9,141,272,147,27,158,175,50,187,189,320,71,93,221,225,226,359,363,241,123
|
2672,1548,2404,385,499,2353,562,147,2579,363,9,187,27,241,439,718,158,221,93,388,1874,1996,1101,2407,2505,2535,1023,189,2489,982,1409,755,1463,50,2345,1882,1855,1528,123,1746,1715,827,2117,175,1208,2043,2044,2097,225,1417,1912,2413,2123,71,2100,1599,272,2385,1986,320,2167,359,141,1376,1704,226
|
-1.9200896765948166,-0.27703285170862874,-0.8901609796463711,0.8800131050184969,0.6576886443457405,-0.8349780072652183,0.5577119571515898,1.858096452664984,-1.2132888500172512,0.9207797152191141,3.601980510099323,1.561812043982834,3.0018786097104724,1.3136668502909221,0.7699015142883784,0.3375549865593367,1.7648798340833782,1.3892066414158972,2.2387939765464413,0.8800131050184969,-0.462815185693309,-0.5318785727630885,-0.001127805810301048,-0.8901609796463711,-1.0399582580540272,-1.0971550435827746,0.061932036437784624,1.549648138953408,-1.0021412347204408,0.09320779573109034,-0.19451519653859392,0.2925118928589216,-0.22738159228350283,2.6577600342457113,-0.8167006259673601,-0.462815185693309,-0.4456774203599463,-0.26043517265107846,1.983936246561302,-0.377629316099032,-0.36074150382824394,0.23190917857868676,-0.6017771358819511,1.658237345935038,-0.0648782670729416,-0.5492740993843713,-0.5492740993843713,-0.5842230489234069,1.3766833583434828,-0.19451519653859392,-0.4800038669191164,-0.8901609796463711,-0.6017771358819511,2.420435656490256,-0.5842230489234069,-0.29367816551779385,1.211424359795403,-0.8533136017184143,-0.514535240785251,1.0414145845970093,-0.6370462182791121,0.9478015835630615,1.8926803722806396,-0.1618337970909173,-0.3439027766845685,1.3766833583434828
| 2,702
|
Late endosome
| 14
| 52
| 2.598458
| 0.009364
|
O15118,P11717,Q9P253,P07602,P11279,Q9NZJ7,Q14108,Q8IV08,Q96PU5,Q8TCT8,P51790,Q99538,O15400,Q9BUN8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
63,417,486,4,387,427,29,19,280,118,242,121,475,413
|
2503,699,63,475,1146,501,1229,4,1323,1154,1589,387,417,2090,1676,863,1023,1522,1740,1410,1201,242,1905,1855,1715,29,2204,1281,19,558,1046,118,1394,280,780,2047,121,1836,781,413,782,1698,1578,1244,427,2051,486,1581,1926,1001,1016,662
|
-1.0399582580540272,0.3673920803157548,2.472830381816948,0.700019999999374,-0.032915728384741015,0.6435101106197167,-0.08092564237043719,4.00405433878558,-0.14556179771058245,-0.032915728384741015,-0.29367816551779385,0.8800131050184969,0.8114351982042777,-0.5842230489234069,-0.3439027766845685,0.2013703373493341,0.061932036437784624,-0.26043517265107846,-0.377629316099032,-0.19451519653859392,-0.0648782670729416,1.3136668502909221,-0.4800038669191164,-0.4456774203599463,-0.36074150382824394,3.0018786097104724,-0.6725321288961622,-0.11315387381905866,3.2085718590601604,0.5720990698697436,0.04623097246479662,2.0065339889232616,-0.17815150752877743,1.1985189212016558,0.2774200528143013,-0.5492740993843713,1.9952458014491112,-0.4285902586631195,0.2774200528143013,0.8252148517366122,0.2774200528143013,-0.3439027766845685,-0.27703285170862874,-0.08092564237043719,0.7976231963964028,-0.5492740993843713,0.6859434192423728,-0.27703285170862874,-0.4800038669191164,0.09320779573109034,0.07759089922445578,0.42661358757948437
| 2,702
|
Muscle stiffness
| 8
| 15
| 2.588097
| 0.009651
|
P07602,Q15392,Q9NZJ7,P52732,P23786,P53985,Q9Y3Z3,P06753
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,166,427,329,105,271,342,440
|
2486,440,4,889,105,1359,329,271,1102,1857,166,479,714,427,342
|
-1.0021412347204408,0.7699015142883784,4.00405433878558,0.17067086843316673,2.096080199744481,-0.1618337970909173,1.0014765288625636,1.211424359795403,-0.001127805810301048,-0.4456774203599463,1.705870022831379,0.700019999999374,0.35249256146592,0.7976231963964028,0.9747001337238531
| 2,702
|
Monooxygenase activity
| 6
| 9
| 2.571168
| 0.010136
|
Q16850,P30519,Q9BU89,P09601,P61457,Q14534
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
65,35,173,334,208,311
|
1609,334,35,208,311,367,65,652,173
|
-0.31037139890127774,0.9881035286247505,2.915245805395765,1.4390369219353498,1.0810841689575286,0.9207797152191141,2.45192727608413,0.4413258066063131,1.6701813099617207
| 2,702
|
Subsets and Splits
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