term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Intrinsic component of endoplasmic reticulum membrane
| 17
| 45
| 3.022457
| 0.002507
|
Q15629,A0FGR8,Q9P035,Q9NQC3,O75844,Q96A33,Q86XL3,P57088,Q8TCT9,Q8N4V1,P10321,O95470,Q9Y282,Q8TB61,Q9UBM7,Q9Y4P3,Q8TCT8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
64,317,312,131,67,250,102,382,168,9,326,107,45,152,153,350,191
|
317,701,1224,67,1427,107,2099,326,2346,1462,1754,572,382,1405,739,1411,1438,64,979,518,1768,102,9,1289,152,191,168,1625,250,1212,1107,409,938,889,131,909,312,1029,854,153,1668,1194,45,350,1863
|
1.0416407333608675,0.31612783470675104,-0.09007741527544748,2.525606359287873,-0.21607946299314143,2.0899995453915405,-0.5774483420396528,1.0143650321652233,-0.7801186405050577,-0.23437919882369965,-0.3835820044684915,0.4901999107033141,0.8752281069462309,-0.19785570229010588,0.28370179506564897,-0.19785570229010588,-0.21607946299314143,2.5628717612311127,0.08383480077369695,0.5822271013569861,-0.3835820044684915,2.1420319569801767,3.724959724908723,-0.1257092085342695,1.7738458790955642,1.503924297502507,1.6352852637773565,-0.30834940175024095,1.2793186260964378,-0.07237000350541305,-0.0022514235063176217,0.8182439888074761,0.11779590878562075,0.15149219850709802,1.9187055275737044,0.13467692383293534,1.06873759915191,0.04960511328482398,0.18492735557866916,1.7510836692846126,-0.3270376997249967,-0.05473421435229654,2.874250799697163,0.9592685631657338,-0.4216838952161537
| 2,702
|
Anion transmembrane transporter activity
| 25
| 46
| 3.008338
| 0.002627
|
O00400,Q9BXP2,P41440,P21796,P45880,Q9C0H2,O43681,Q8TB61,Q6NUK1,P11166,O15439,Q9HC21,Q9H2D1,P51790,Q9H2H9,P12236,Q9BQT8,Q9Y619,P33527,P04920,Q9Y277,Q9UBX3,P53985,P51798,Q96QD8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
264,528,271,15,16,20,531,152,419,539,422,432,51,185,198,457,93,351,352,484,232,109,244,248,508
|
2036,264,422,531,736,989,966,484,856,1329,539,779,457,15,352,271,16,185,248,244,1020,1312,730,2109,419,1514,152,2231,809,508,1052,558,93,528,20,51,198,1133,432,109,645,232,812,351,2460,840
|
-0.5379930941294808,1.2146655480675908,0.7749899149252996,0.5517730351345772,0.28370179506564897,0.0667537675442864,0.08383480077369695,0.6424844207170954,0.1682421911682641,-0.16163385385214332,0.536463418458696,0.2345983492140732,0.701892290350493,3.558604191488058,0.9453792994602913,1.188515758083854,3.515789489534347,1.5281289711930328,1.2793186260964378,1.2921274336650987,0.04960511328482398,-0.1436346549150024,0.2999454932185619,-0.5774483420396528,0.7894576895397357,-0.2527554805154473,1.7738458790955642,-0.6574202145206469,0.2181049920661174,0.5973722597638846,0.03238835570877815,0.5210982679469837,2.2440618128355347,0.5670274774060957,3.3618378249093492,2.822658973915516,1.4795736761747307,-0.019675434888960938,0.7604719773481496,2.0899995453915405,0.39613357596639254,1.3429641997032904,0.2181049920661174,0.9592685631657338,-0.9062528889503797,0.20154814096271612
| 2,702
|
Abnormal circulating cholesterol concentration
| 11
| 29
| 2.892852
| 0.003818
|
Q9BV10,Q14739,P61916,P07602,Q15392,Q9NZJ7,Q8IWV7,P37268,Q15800,Q9UBM7,O75431
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
200,235,300,13,142,336,144,147,283,153,252
|
252,967,990,13,147,525,897,2470,338,2486,1338,300,1615,1043,976,1344,235,142,1963,283,501,144,756,1562,200,549,336,153,645
|
1.2664695220524946,0.08383480077369695,0.0667537675442864,3.6358051961034,1.7964787566429434,0.5670274774060957,0.13467692383293534,-0.9276215217752557,0.9869083646757261,-0.9490913261043828,-0.16163385385214332,1.1090521543190752,-0.30834940175024095,0.03238835570877815,0.08383480077369695,-0.16163385385214332,1.3303143323167068,1.8301884436274014,-0.4794579332236154,1.148975957368919,0.6124633021363719,1.807747107129735,0.2673963211845321,-0.2712088850102407,1.4673431398478316,0.536463418458696,1.0006594538170546,1.7510836692846126,0.39613357596639254
| 2,702
|
Hyperlipidemia
| 7
| 24
| 2.883881
| 0.003928
|
O75844,P06280,O95470,P22830,O75431,P28070,P23786
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
67,104,107,281,252,125,63
|
841,1195,252,67,107,967,104,990,281,63,125,1872,1173,525,879,338,2164,976,1344,756,983,1562,645,672
|
0.18492735557866916,-0.07237000350541305,1.2664695220524946,2.525606359287873,2.0899995453915405,0.08383480077369695,2.1316806866838474,0.0667537675442864,1.148975957368919,2.5721316468788222,1.9513955835040788,-0.44085843678176667,-0.05473421435229654,0.5670274774060957,0.15149219850709802,0.9869083646757261,-0.6172554898593413,0.08383480077369695,-0.16163385385214332,0.2673963211845321,0.08383480077369695,-0.2712088850102407,0.39613357596639254,0.36431084877418707
| 2,702
|
primary active transporter
| 10
| 24
| 2.863745
| 0.004187
|
Q9NS69,Q15388,Q6P4A7,O60888,Q8N4H5,P16615,P05023,P98194,Q9Y5J7,O75381
|
Functions
|
Panther Protein class
|
panther_protein_class
|
0,295,259,225,39,292,363,369,342,319
|
225,319,1673,692,363,1457,944,292,737,707,2223,369,295,1312,518,259,39,604,809,409,1133,871,0,342
|
1.3555748844625495,1.0416407333608675,-0.3458054921469844,0.33224923450336813,0.9174606497851514,-0.23437919882369965,0.10084869034597146,1.122403168752099,0.28370179506564897,0.31612783470675104,-0.6574202145206469,0.9034306979462009,1.122403168752099,-0.1436346549150024,0.5822271013569861,1.240649509692531,2.9503340260738637,0.4434266881560912,0.2181049920661174,0.8182439888074761,-0.019675434888960938,0.1682421911682641,4.339098672789817,0.9869083646757261
| 2,702
|
Mitochondrial carrier domain superfamily [IPR023395]
| 10
| 18
| 2.857692
| 0.004267
|
Q6NUK1,O43772,Q70HW3,Q9Y6C9,Q9UBX3,Q9NZJ7,Q9HC21,Q9H2D1,Q9BQT8,Q9Y619
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
419,162,5,332,109,336,432,51,93,351
|
162,736,989,856,779,457,1122,1020,419,5,93,51,432,336,109,645,351,332
|
1.6820076128894363,0.28370179506564897,0.0667537675442864,0.1682421911682641,0.2345983492140732,0.701892290350493,-0.019675434888960938,0.04960511328482398,0.7894576895397357,3.857928935292173,2.2440618128355347,2.822658973915516,0.7604719773481496,1.0006594538170546,2.0899995453915405,0.39613357596639254,0.9592685631657338,1.0143650321652233
| 2,702
|
SLC25 family of mitochondrial transporters
| 10
| 18
| 2.857692
| 0.004267
|
Q6NUK1,O43772,Q70HW3,Q9Y6C9,Q9UBX3,Q9NZJ7,Q9HC21,Q9H2D1,Q9BQT8,Q9Y619
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
419,162,5,332,109,336,432,51,93,351
|
162,736,989,856,779,457,1122,1020,419,5,93,51,432,336,109,645,351,332
|
1.6820076128894363,0.28370179506564897,0.0667537675442864,0.1682421911682641,0.2345983492140732,0.701892290350493,-0.019675434888960938,0.04960511328482398,0.7894576895397357,3.857928935292173,2.2440618128355347,2.822658973915516,0.7604719773481496,1.0006594538170546,2.0899995453915405,0.39613357596639254,0.9592685631657338,1.0143650321652233
| 2,702
|
Mitochondrial substrate/solute carrier [IPR018108]
| 10
| 18
| 2.857692
| 0.004267
|
Q6NUK1,O43772,Q70HW3,Q9Y6C9,Q9UBX3,Q9NZJ7,Q9HC21,Q9H2D1,Q9BQT8,Q9Y619
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
419,162,5,332,109,336,432,51,93,351
|
162,736,989,856,779,457,1122,1020,419,5,93,51,432,336,109,645,351,332
|
1.6820076128894363,0.28370179506564897,0.0667537675442864,0.1682421911682641,0.2345983492140732,0.701892290350493,-0.019675434888960938,0.04960511328482398,0.7894576895397357,3.857928935292173,2.2440618128355347,2.822658973915516,0.7604719773481496,1.0006594538170546,2.0899995453915405,0.39613357596639254,0.9592685631657338,1.0143650321652233
| 2,702
|
Glycerophospholipid biosynthesis
| 7
| 27
| 2.853142
| 0.004329
|
Q9NPH0,Q8NF37,Q9NQZ5,Q6P1A2,Q8IV08,P35790,P48651
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
4,103,17,212,85,59,124
|
702,1083,1300,299,2219,59,1463,1174,124,1149,2376,1685,1313,212,1157,85,1899,437,103,519,757,1321,2332,4,17,1109,628
|
0.31612783470675104,-0.0022514235063176217,-0.1436346549150024,1.1090521543190752,-0.6574202145206469,2.6180971611507324,-0.23437919882369965,-0.05473421435229654,1.9622324023613926,-0.03716952921365007,-0.8008978009850447,-0.3458054921469844,-0.1436346549150024,1.4056301198534875,-0.03716952921365007,2.2841363418193175,-0.44085843678176667,0.7459035635880372,2.1420319569801767,0.5822271013569861,0.2673963211845321,-0.1436346549150024,-0.759434892091634,3.9417705569579184,3.4359598674765164,-0.0022514235063176217,0.42772059381643684
| 2,702
|
Organic anion transport
| 19
| 43
| 2.807339
| 0.004995
|
O00400,P41440,P07602,Q8TB61,Q6NUK1,P11166,O15439,Q9HC21,Q9H2D1,Q9H2H9,Q9NZJ7,P12236,Q9BQT8,Q9Y619,P33527,P04920,Q9UBX3,P53985,Q96QD8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
264,271,13,152,419,539,422,432,51,198,336,457,93,351,352,484,109,244,508
|
264,422,736,989,942,966,894,484,856,1170,13,1329,539,779,457,2465,1085,1086,352,271,803,244,1020,631,1312,419,1514,152,2231,809,508,558,93,51,198,1133,432,336,109,645,812,351,840
|
1.2146655480675908,0.7749899149252996,0.28370179506564897,0.0667537675442864,0.10084869034597146,0.08383480077369695,0.13467692383293534,0.6424844207170954,0.1682421911682641,-0.05473421435229654,3.6358051961034,-0.16163385385214332,0.536463418458696,0.2345983492140732,0.701892290350493,-0.9276215217752557,-0.0022514235063176217,-0.0022514235063176217,0.9453792994602913,1.188515758083854,0.2181049920661174,1.2921274336650987,0.04960511328482398,0.411956352337547,-0.1436346549150024,0.7894576895397357,-0.2527554805154473,1.7738458790955642,-0.6574202145206469,0.2181049920661174,0.5973722597638846,0.5210982679469837,2.2440618128355347,2.822658973915516,1.4795736761747307,-0.019675434888960938,0.7604719773481496,1.0006594538170546,2.0899995453915405,0.39613357596639254,0.2181049920661174,0.9592685631657338,0.20154814096271612
| 2,702
|
Organophosphate ester transport
| 16
| 26
| 2.787292
| 0.005315
|
P33527,Q6NUK1,O15439,O00400,Q14108,Q99808,Q8WTV0,P61916,P41440,P22059,Q9HC21,P12236,Q9H2D1,P08183,Q8TB61,Q8NB49
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
352,419,422,264,8,558,202,300,271,582,432,457,51,84,152,604
|
264,422,736,856,84,779,457,582,1794,352,271,1149,300,631,8,730,419,604,152,2231,202,558,2332,51,432,1524
|
1.2146655480675908,0.7749899149252996,0.28370179506564897,0.1682421911682641,2.3040194739784066,0.2345983492140732,0.701892290350493,0.4746659679952571,-0.4025919634436768,0.9453792994602913,1.188515758083854,-0.03716952921365007,1.1090521543190752,0.411956352337547,3.724959724908723,0.2999454932185619,0.7894576895397357,0.4434266881560912,1.7738458790955642,-0.6574202145206469,1.4550755191396691,0.5210982679469837,-0.759434892091634,2.822658973915516,0.7604719773481496,-0.2527554805154473
| 2,702
|
Vacuole organization
| 9
| 36
| 2.784109
| 0.005368
|
P11117,P10253,P04062,Q14108,P16615,P54802,P50897,O75503,O14773
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,196,134,8,292,77,22,247,157
|
1031,157,550,247,134,1603,675,196,65,706,292,1647,532,803,847,22,1336,77,949,973,1340,1095,8,1808,1348,462,1517,1211,1521,482,689,2182,811,1781,307,1424
|
0.03238835570877815,1.7166949344659548,0.5210982679469837,1.2793186260964378,1.90774847949041,-0.30834940175024095,0.3483101035432623,1.4795736761747307,2.5349567864503544,0.31612783470675104,1.122403168752099,-0.3270376997249967,0.5517730351345772,0.2181049920661174,0.18492735557866916,3.2708634537820394,-0.16163385385214332,2.4115869799105853,0.10084869034597146,0.08383480077369695,-0.16163385385214332,-0.0022514235063176217,3.724959724908723,-0.4025919634436768,-0.16163385385214332,0.701892290350493,-0.2527554805154473,-0.07237000350541305,-0.2527554805154473,0.6574151799611627,0.3483101035432623,-0.6172554898593413,0.2181049920661174,-0.3835820044684915,1.0956577244042058,-0.19785570229010588
| 2,702
|
Regulation of lipid biosynthetic process
| 10
| 24
| 2.772429
| 0.005564
|
O75477,P16435,Q8NF37,Q8WTV0,P31749,O94905,Q6P1A2,Q13510,P30536,Q9UBM7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
192,258,103,202,365,180,212,55,151,153
|
1033,192,1826,180,1674,894,363,991,258,151,365,532,860,2437,2427,55,1347,212,103,202,519,153,1912,911
|
0.03238835570877815,1.4917673289663298,-0.4216838952161537,1.5641657435116996,-0.3458054921469844,0.13467692383293534,0.9174606497851514,0.0667537675442864,1.240649509692531,1.7738458790955642,0.9174606497851514,0.5517730351345772,0.1682421911682641,-0.8849845746322226,-0.8638157361636718,2.6994624661868474,-0.16163385385214332,1.4056301198534875,2.1420319569801767,1.4550755191396691,0.5822271013569861,1.7510836692846126,-0.44085843678176667,0.13467692383293534
| 2,702
|
Sterol biosynthetic process
| 11
| 22
| 2.754845
| 0.005872
|
O75477,P16435,Q16850,Q14739,Q14534,Q15392,P48449,P37268,O94905,Q6P1A2,Q9UBM7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
192,258,139,235,173,142,242,147,180,212,153
|
192,1427,180,2529,1459,694,258,147,2321,242,1876,2225,2520,173,235,2228,142,1963,283,139,212,153
|
1.4917673289663298,-0.21607946299314143,1.5641657435116996,-1.0359996897457213,-0.23437919882369965,0.33224923450336813,1.240649509692531,1.7964787566429434,-0.759434892091634,1.3048961711518003,-0.44085843678176667,-0.6574202145206469,-1.0141164567184937,1.5998828218041645,1.3303143323167068,-0.6574202145206469,1.8301884436274014,-0.4794579332236154,1.148975957368919,1.8413617509235753,1.4056301198534875,1.7510836692846126
| 2,702
|
Disproportionate short stature
| 9
| 21
| 2.740604
| 0.006133
|
P16278,Q9UHX1,O00116,Q9BV10,Q14739,Q15392,Q03164,Q96HY6,Q9UBM7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
36,38,290,200,235,142,48,339,153
|
290,1083,2390,778,845,36,2555,532,995,48,235,1764,142,357,932,1158,2330,339,200,153,38
|
1.122403168752099,-0.0022514235063176217,-0.8217731668728108,0.2345983492140732,0.18492735557866916,3.000210798187082,-1.1022866602862778,0.5517730351345772,0.0667537675442864,2.839934928116633,1.3303143323167068,-0.3835820044684915,1.8301884436274014,0.9314434222343889,0.11779590878562075,-0.03716952921365007,-0.759434892091634,0.9869083646757261,1.4673431398478316,1.7510836692846126,2.958693159055178
| 2,702
|
Cholesterol metabolism with bloch and kandutschrussell pathways
| 8
| 21
| 2.728816
| 0.006356
|
Q9BWD1,Q16850,Q14739,Q14534,Q15392,P48449,P37268,Q9UBM7
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
6,139,235,173,142,242,147,153
|
701,1599,1427,1674,1035,694,1576,147,242,1064,2225,2520,173,235,2228,142,1963,283,139,6,153
|
0.31612783470675104,-0.30834940175024095,-0.21607946299314143,-0.3458054921469844,0.03238835570877815,0.33224923450336813,-0.2897399955466822,1.7964787566429434,1.3048961711518003,0.015103007549675692,-0.6574202145206469,-1.0141164567184937,1.5998828218041645,1.3303143323167068,-0.6574202145206469,1.8301884436274014,-0.4794579332236154,1.148975957368919,1.8413617509235753,3.805333958926554,1.7510836692846126
| 2,702
|
Tetrapyrrole binding
| 9
| 15
| 2.703814
| 0.006855
|
O43169,Q16850,Q8WUJ1,O00264,O15173,Q7KZN9,P09601,P30519,Q9H7Z7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
2,139,174,243,83,213,86,29,378
|
243,83,2,1036,86,1830,29,139,398,213,174,1318,1076,378,2064
|
1.2921274336650987,2.3040194739784066,3.979807696470662,0.03238835570877815,2.2741564208043514,-0.4216838952161537,3.193293290882018,1.8413617509235753,0.8325631260445068,1.4056301198534875,1.5998828218041645,-0.1436346549150024,0.015103007549675692,0.8893532800594045,-0.5379930941294808
| 2,702
|
Ion channel transport
| 11
| 27
| 2.702905
| 0.006874
|
Q96PU5,Q9Y487,Q93050,P16615,P05023,P98194,Q9C0H2,Q9HD20,P51790,P51798,P21281
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
98,37,40,292,363,369,20,56,185,248,472
|
363,1457,292,737,472,2320,707,1608,1577,1927,185,248,2223,592,369,925,1343,501,730,604,40,98,20,56,1112,37,734
|
0.9174606497851514,-0.23437919882369965,1.122403168752099,0.28370179506564897,0.672293189318447,-0.759434892091634,0.31612783470675104,-0.30834940175024095,-0.2897399955466822,-0.46011623230476806,1.5281289711930328,1.2793186260964378,-0.6574202145206469,0.4590750194134483,0.9034306979462009,0.11779590878562075,-0.16163385385214332,0.6124633021363719,0.2999454932185619,0.4434266881560912,2.941956184280774,2.1831648884950323,3.3618378249093492,2.690507421713021,-0.0022514235063176217,2.975355597745126,0.2999454932185619
| 2,702
|
Abnormality of head blood vessel
| 9
| 23
| 2.686014
| 0.007231
|
P16278,P10619,P07602,Q9NZJ7,P17900,Q13510,P48651,P06865,Q9Y4P3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
36,72,13,336,82,55,124,253,350
|
841,1223,2574,253,13,675,72,2012,36,82,1085,356,1609,124,2076,1931,55,829,2649,934,336,1859,350
|
0.18492735557866916,-0.09007741527544748,-1.1470183659657167,1.2664695220524946,3.6358051961034,0.3483101035432623,2.469019679033845,-0.51839569402218,3.000210798187082,2.333654152549082,-0.0022514235063176217,0.9314434222343889,-0.30834940175024095,1.9622324023613926,-0.5576770803133537,-0.46011623230476806,2.6994624661868474,0.20154814096271612,-1.570450064901612,0.11779590878562075,1.0006594538170546,-0.4216838952161537,0.9592685631657338
| 2,702
|
Sensorimotor neuropathy
| 13
| 29
| 2.677858
| 0.007409
|
Q8N2K0,P07196,Q5KU26,Q9NSE4,P41440,P07602,Q9NZJ7,P05023,Q9NR77,P00403,Q9Y2R0,Q13217,O95831
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
359,364,106,172,271,13,336,363,115,114,21,407,313
|
744,1533,416,313,114,363,364,13,2409,1926,2669,1463,271,1681,1682,1877,2376,828,407,1156,106,359,983,545,115,172,336,21,660
|
0.2673963211845321,-0.2712088850102407,0.7894576895397357,1.055211388917935,2.015974080477711,0.9174606497851514,0.9174606497851514,3.6358051961034,-0.8427455410647996,-0.46011623230476806,-1.7717716596755038,-0.23437919882369965,1.188515758083854,-0.3458054921469844,-0.3458054921469844,-0.44085843678176667,-0.8008978009850447,0.20154814096271612,0.8182439888074761,-0.03716952921365007,2.100461504027298,0.9314434222343889,0.08383480077369695,0.536463418458696,2.015974080477711,1.6117183489592206,1.0006594538170546,3.2938193341266992,0.38025187320722004
| 2,702
|
Biliary tract abnormality
| 13
| 24
| 2.675929
| 0.007452
|
Q9UJW0,P04062,Q10713,Q14108,Q14739,P50542,P07602,Q9NZJ7,Q9NSD9,O95202,Q5XKP0,P09601,O96028
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
331,134,453,8,235,490,13,336,303,241,371,86,123
|
531,241,123,967,134,13,86,2465,2449,2074,490,1682,453,1180,2301,8,235,371,1968,303,336,331,1594,1220
|
0.5517730351345772,1.3048961711518003,1.9622324023613926,0.08383480077369695,1.90774847949041,3.6358051961034,2.2741564208043514,-0.9276215217752557,-0.9062528889503797,-0.5576770803133537,0.6275005747563835,-0.3458054921469844,0.7166140404526318,-0.05473421435229654,-0.7388457718106729,3.724959724908723,1.3303143323167068,0.9034306979462009,-0.4794579332236154,1.1090521543190752,1.0006594538170546,1.0143650321652233,-0.2897399955466822,-0.07237000350541305
| 2,702
|
Exopeptidase activity
| 12
| 28
| 2.645815
| 0.008149
|
Q9HB40,Q9NQH7,P02786,O75844,Q9NZ08,P10619,P55786,Q7Z2K6,Q9H3G5,P42785,O14773,Q9UIQ6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
32,284,322,67,99,72,74,334,24,31,157,159
|
157,67,362,322,1979,72,2687,2584,1277,1610,31,74,2325,668,334,1813,480,1075,2173,757,24,2152,32,284,688,2066,99,159
|
1.7166949344659548,2.525606359287873,0.9174606497851514,1.028025369515471,-0.4988841983587244,2.469019679033845,-2.552388673060089,-1.169549198546752,-0.1257092085342695,-0.30834940175024095,3.0818850191066662,2.4308266158331455,-0.759434892091634,0.36431084877418707,1.0006594538170546,-0.4025919634436768,0.6574151799611627,0.015103007549675692,-0.6172554898593413,0.2673963211845321,3.255479531632857,-0.5973075767254589,3.0494299565613403,1.148975957368919,0.3483101035432623,-0.5379930941294808,2.1831648884950323,1.7166949344659548
| 2,702
|
Anion transport
| 33
| 66
| 2.637781
| 0.008345
|
O00400,Q9BXP2,P41440,P07602,P21796,P45880,Q9C0H2,P30536,O43681,Q8TB61,Q6NUK1,P11166,O15439,Q99808,Q9UHG3,Q15907,Q9HC21,Q9H2D1,P51790,Q9H2H9,Q9NZJ7,P12236,P08183,Q9BQT8,Q9Y619,P33527,P04920,Q9Y277,Q9UBX3,Q9H0H5,P53985,P51798,Q96QD8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
264,528,271,13,15,16,20,151,531,152,419,539,422,558,43,429,432,51,185,198,336,457,84,93,351,352,484,232,109,239,244,248,508
|
2036,264,422,531,736,1492,989,942,966,894,484,856,1170,13,84,1329,539,779,457,2465,1085,15,1086,151,352,271,16,803,185,248,244,574,1122,1020,631,1312,429,730,2109,419,1514,152,2231,809,508,1052,558,93,528,20,239,51,198,1133,432,733,336,109,43,645,232,812,1009,351,2460,840
|
-0.5379930941294808,1.2146655480675908,0.7749899149252996,0.5517730351345772,0.28370179506564897,-0.2527554805154473,0.0667537675442864,0.10084869034597146,0.08383480077369695,0.13467692383293534,0.6424844207170954,0.1682421911682641,-0.05473421435229654,3.6358051961034,2.3040194739784066,-0.16163385385214332,0.536463418458696,0.2345983492140732,0.701892290350493,-0.9276215217752557,-0.0022514235063176217,3.558604191488058,-0.0022514235063176217,1.7738458790955642,0.9453792994602913,1.188515758083854,3.515789489534347,0.2181049920661174,1.5281289711930328,1.2793186260964378,1.2921274336650987,0.4901999107033141,-0.019675434888960938,0.04960511328482398,0.411956352337547,-0.1436346549150024,0.7604719773481496,0.2999454932185619,-0.5774483420396528,0.7894576895397357,-0.2527554805154473,1.7738458790955642,-0.6574202145206469,0.2181049920661174,0.5973722597638846,0.03238835570877815,0.5210982679469837,2.2440618128355347,0.5670274774060957,3.3618378249093492,1.3176250631188255,2.822658973915516,1.4795736761747307,-0.019675434888960938,0.7604719773481496,0.2999454932185619,1.0006594538170546,2.0899995453915405,2.8912919988892094,0.39613357596639254,1.3429641997032904,0.2181049920661174,0.0667537675442864,0.9592685631657338,-0.9062528889503797,0.20154814096271612
| 2,702
|
Glycosphingolipid metabolism
| 9
| 15
| 2.627515
| 0.008601
|
A0FGR8,P16278,P04062,P10619,P06280,P07602,P17900,Q13510,P06865
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
317,36,134,72,104,13,82,55,253
|
317,531,134,104,253,13,675,72,36,82,55,2614,1107,1165,336
|
1.0416407333608675,0.5517730351345772,1.90774847949041,2.1316806866838474,1.2664695220524946,3.6358051961034,0.3483101035432623,2.469019679033845,3.000210798187082,2.333654152549082,2.6994624661868474,-1.307106361795847,-0.0022514235063176217,-0.03716952921365007,1.0006594538170546
| 2,702
|
Azurophil granule membrane
| 8
| 19
| 2.627228
| 0.008608
|
P10253,Q8NF37,P07602,O15260,Q92542,Q07065,P11279,P42785
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
196,103,13,207,211,249,221,31
|
207,1300,1711,441,13,196,221,2199,31,803,1757,249,1348,103,211,757,657,336,1524
|
1.4304282132683406,-0.1436346549150024,-0.3646533883592373,0.7312843575943586,3.6358051961034,1.4795736761747307,1.3806795740768194,-0.6372927951239112,3.0818850191066662,0.2181049920661174,-0.3835820044684915,1.2793186260964378,-0.16163385385214332,2.1420319569801767,1.4180481184366847,0.2673963211845321,0.38025187320722004,1.0006594538170546,-0.2527554805154473
| 2,702
|
Secondary alcohol metabolic process
| 16
| 36
| 2.623074
| 0.008714
|
O75477,P16435,O15118,P04062,Q8WTV0,Q16850,Q9BQE5,Q14534,Q15392,Q14739,P48449,P37268,O94905,Q6P1A2,Q15800,Q9UBM7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
192,258,69,134,202,139,12,173,142,235,242,147,180,212,283,153
|
69,2274,192,1826,1427,180,2529,134,1459,694,258,2345,147,2321,242,2568,860,2643,1876,300,1932,2225,2520,173,235,2228,142,1963,283,139,212,202,2430,12,153,1564
|
2.497417369060405,-0.7183505049899396,1.4917673289663298,-0.4216838952161537,-0.21607946299314143,1.5641657435116996,-1.0359996897457213,1.90774847949041,-0.23437919882369965,0.33224923450336813,1.240649509692531,-0.7801186405050577,1.7964787566429434,-0.759434892091634,1.3048961711518003,-1.124597841923488,0.1682421911682641,-1.497135064240729,-0.44085843678176667,1.1090521543190752,-0.46011623230476806,-0.6574202145206469,-1.0141164567184937,1.5998828218041645,1.3303143323167068,-0.6574202145206469,1.8301884436274014,-0.4794579332236154,1.148975957368919,1.8413617509235753,1.4056301198534875,1.4550755191396691,-0.8638157361636718,3.642742245523358,1.7510836692846126,-0.2712088850102407
| 2,702
|
Arthritis
| 12
| 35
| 2.62019
| 0.008788
|
O75844,Q9NZ08,P04062,Q14108,P06280,P10321,Q14739,Q96HY6,Q13510,P51798,O15460,P28070
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
67,99,134,8,104,326,235,339,55,248,220,125
|
735,220,67,1867,967,134,104,1303,326,2340,2465,356,2343,125,1064,847,248,2400,2076,1986,1405,1615,55,8,235,1764,620,1481,1160,2649,934,339,99,720,1113
|
0.28370179506564897,1.3806795740768194,2.525606359287873,-0.44085843678176667,0.08383480077369695,1.90774847949041,2.1316806866838474,-0.1436346549150024,1.0143650321652233,-0.7801186405050577,-0.9276215217752557,0.9314434222343889,-0.7801186405050577,1.9513955835040788,0.015103007549675692,0.18492735557866916,1.2793186260964378,-0.8217731668728108,-0.5576770803133537,-0.4988841983587244,-0.19785570229010588,-0.30834940175024095,2.6994624661868474,3.724959724908723,1.3303143323167068,-0.3835820044684915,0.42772059381643684,-0.23437919882369965,-0.03716952921365007,-1.570450064901612,0.11779590878562075,0.9869083646757261,2.1831648884950323,0.31612783470675104,-0.0022514235063176217
| 2,702
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 12
| 28
| 2.609304
| 0.009073
|
P16435,Q8NB78,Q32P28,Q16850,Q14534,Q9BU89,P07237,Q15800,P09601,O15460,P30519,P13674
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
258,195,357,139,173,145,381,283,86,220,29,254
|
2654,701,220,1169,522,2295,1638,1035,381,86,254,258,2395,29,575,1883,925,173,283,139,357,1048,398,1767,195,145,1421,1948
|
-1.6700298575117414,0.31612783470675104,1.3806795740768194,-0.05473421435229654,0.5670274774060957,-0.7388457718106729,-0.3270376997249967,0.03238835570877815,0.8752281069462309,2.2741564208043514,1.2535798932893194,1.240649509692531,-0.8217731668728108,3.193293290882018,0.4901999107033141,-0.44085843678176667,0.11779590878562075,1.5998828218041645,1.148975957368919,1.8413617509235753,0.9314434222343889,0.03238835570877815,0.8325631260445068,-0.3835820044684915,1.4917673289663298,1.807747107129735,-0.19785570229010588,-0.46011623230476806
| 2,702
|
Endoplasmic reticulum golgi intermediate compartment membrane
| 13
| 19
| 2.609051
| 0.009079
|
Q12907,Q13190,P24390,Q10472,Q9Y282,Q9BVK6,O95070,O75396,O15260,Q15363,Q15904,Q9Y3B3,P51572
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
541,323,10,491,45,175,269,550,207,111,501,150,572
|
207,988,550,269,10,2346,879,614,572,728,491,541,323,111,501,175,45,939,150
|
1.4304282132683406,0.0667537675442864,0.5210982679469837,1.188515758083854,3.6703575558394306,-0.7801186405050577,0.15149219850709802,0.42772059381643684,0.4901999107033141,0.2999454932185619,0.6275005747563835,0.536463418458696,1.028025369515471,2.079509582008797,0.6124633021363719,1.5998828218041645,2.874250799697163,0.11779590878562075,1.7851784018367542
| 2,702
|
Membrane lipid catabolic process
| 6
| 11
| 2.590894
| 0.009573
|
P04062,P06280,O95470,P17900,P50897,Q13510
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
134,104,107,82,22,55
|
107,134,817,104,253,675,82,22,55,605,1165
|
2.0899995453915405,1.90774847949041,0.20154814096271612,2.1316806866838474,1.2664695220524946,0.3483101035432623,2.333654152549082,3.2708634537820394,2.6994624661868474,0.4434266881560912,-0.03716952921365007
| 2,702
|
Inner mitochondrial membrane organization
| 12
| 21
| 2.585439
| 0.009725
|
Q9H3K2,Q9P0J0,O60313,Q13505,O95202,Q8WWC4,Q9BUR5,Q9NX63,Q9Y5J7,Q5XKP0,O75431,Q6UXV4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
391,132,416,42,241,438,276,341,342,371,252,413
|
416,252,1673,241,857,2539,42,493,1313,371,413,438,276,391,872,341,132,660,690,342,612
|
0.7894576895397357,1.2664695220524946,-0.3458054921469844,1.3048961711518003,0.1682421911682641,-1.0579885203161268,2.9082562157141907,0.6275005747563835,-0.1436346549150024,0.9034306979462009,0.8038756116143992,0.7459035635880372,1.1753780817167876,0.8610548868787217,0.1682421911682641,0.9869083646757261,1.9187055275737044,0.38025187320722004,0.3483101035432623,0.9869083646757261,0.4434266881560912
| 2,702
|
Sterol binding
| 8
| 15
| 2.570368
| 0.010159
|
O75477,O15118,Q14108,P61916,P21796,P45880,O94905,P30536
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,69,8,300,15,16,180,151
|
69,192,180,1828,15,582,1794,151,16,300,8,834,1735,2332,310
|
2.497417369060405,1.4917673289663298,1.5641657435116996,-0.4216838952161537,3.558604191488058,0.4746659679952571,-0.4025919634436768,1.7738458790955642,3.515789489534347,1.1090521543190752,3.724959724908723,0.20154814096271612,-0.3646533883592373,-0.759434892091634,1.0822196248016487
| 2,702
|
Mitochondrial protein import
| 12
| 34
| 2.564777
| 0.010324
|
Q9NS69,Q99595,Q15388,O14925,Q10713,Q8N4H5,Q13505,Q5JRX3,P21796,Q9NX63,Q9Y5J7,O75431
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,1,295,160,453,39,42,430,15,341,342,252
|
160,648,2626,252,1712,989,1673,724,692,818,1036,2125,779,457,15,969,2539,453,42,295,930,430,39,1,2430,624,871,0,341,645,1594,690,342,612
|
1.7051658996048906,0.38025187320722004,-1.3774562790616307,1.2664695220524946,-0.3646533883592373,0.0667537675442864,-0.3458054921469844,0.2999454932185619,0.33224923450336813,0.20154814096271612,0.03238835570877815,-0.5973075767254589,0.2345983492140732,0.701892290350493,3.558604191488058,0.08383480077369695,-1.0579885203161268,0.7166140404526318,2.9082562157141907,1.122403168752099,0.11779590878562075,0.7604719773481496,2.9503340260738637,4.023672847582024,-0.8638157361636718,0.42772059381643684,0.1682421911682641,4.339098672789817,0.9869083646757261,0.39613357596639254,-0.2897399955466822,0.3483101035432623,0.9869083646757261,0.4434266881560912
| 2,702
|
Protein targeting to mitochondrion
| 21
| 39
| 2.563103
| 0.010374
|
Q9NS69,Q99595,Q9P0J0,P07900,O43615,P30536,Q99797,O14925,Q15388,Q9Y512,Q8N4H5,Q5JRX3,Q9Y371,O95831,P51572,Q10713,P55786,Q9Y5J7,Q9Y5J9,Q9BVV7,O14737
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,132,523,648,151,547,160,295,690,39,430,307,313,572,453,74,342,612,624,233
|
735,233,160,648,1712,1673,1749,313,692,523,2125,2219,151,2103,879,572,74,2140,453,295,930,1313,430,2058,39,1161,1053,1,547,624,868,871,0,132,1166,307,690,342,612
|
0.28370179506564897,1.3303143323167068,1.7051658996048906,0.38025187320722004,-0.3646533883592373,-0.3458054921469844,-0.3835820044684915,1.055211388917935,0.33224923450336813,0.5670274774060957,-0.5973075767254589,-0.6574202145206469,1.7738458790955642,-0.5774483420396528,0.15149219850709802,0.4901999107033141,2.4308266158331455,-0.5973075767254589,0.7166140404526318,1.122403168752099,0.11779590878562075,-0.1436346549150024,0.7604719773481496,-0.5379930941294808,2.9503340260738637,-0.03716952921365007,0.03238835570877815,4.023672847582024,0.536463418458696,0.42772059381643684,0.1682421911682641,0.1682421911682641,4.339098672789817,1.9187055275737044,-0.03716952921365007,1.0956577244042058,0.3483101035432623,0.9869083646757261,0.4434266881560912
| 2,702
|
Atpase coupled transmembrane transporter activity
| 10
| 22
| 2.563011
| 0.010377
|
P33527,Q15388,O15439,O75027,P16615,P05023,P98194,P08183,Q9HD20,P51798
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
352,295,422,394,292,363,369,84,56,248
|
422,394,363,1457,818,84,292,737,472,2320,707,1086,352,1577,1927,248,592,369,295,56,1112,734
|
0.7749899149252996,0.8468333255500231,0.9174606497851514,-0.23437919882369965,0.20154814096271612,2.3040194739784066,1.122403168752099,0.28370179506564897,0.672293189318447,-0.759434892091634,0.31612783470675104,-0.0022514235063176217,0.9453792994602913,-0.2897399955466822,-0.46011623230476806,1.2793186260964378,0.4590750194134483,0.9034306979462009,1.122403168752099,2.690507421713021,-0.0022514235063176217,0.2999454932185619
| 2,702
|
Sterol metabolism
| 10
| 21
| 2.538266
| 0.01114
|
O75477,O15118,P04062,Q16850,Q14739,Q15392,P37268,O94905,Q15800,Q9UBM7
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
192,69,134,139,235,142,147,180,283,153
|
69,192,1427,180,2529,134,694,2345,147,300,1932,2225,2520,235,2228,142,1963,283,139,153,1564
|
2.497417369060405,1.4917673289663298,-0.21607946299314143,1.5641657435116996,-1.0359996897457213,1.90774847949041,0.33224923450336813,-0.7801186405050577,1.7964787566429434,1.1090521543190752,-0.46011623230476806,-0.6574202145206469,-1.0141164567184937,1.3303143323167068,-0.6574202145206469,1.8301884436274014,-0.4794579332236154,1.148975957368919,1.8413617509235753,1.7510836692846126,-0.2712088850102407
| 2,702
|
Cholesterol metabolism
| 10
| 21
| 2.538266
| 0.01114
|
O75477,O15118,P04062,Q16850,Q14739,Q15392,P37268,O94905,Q15800,Q9UBM7
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
192,69,134,139,235,142,147,180,283,153
|
69,192,1427,180,2529,134,694,2345,147,300,1932,2225,2520,235,2228,142,1963,283,139,153,1564
|
2.497417369060405,1.4917673289663298,-0.21607946299314143,1.5641657435116996,-1.0359996897457213,1.90774847949041,0.33224923450336813,-0.7801186405050577,1.7964787566429434,1.1090521543190752,-0.46011623230476806,-0.6574202145206469,-1.0141164567184937,1.3303143323167068,-0.6574202145206469,1.8301884436274014,-0.4794579332236154,1.148975957368919,1.8413617509235753,1.7510836692846126,-0.2712088850102407
| 2,702
|
Ascites
| 8
| 23
| 2.528669
| 0.01145
|
O15118,P04062,Q14108,Q14739,P61916,Q9NSD9,Q13510,P08236
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
69,134,8,235,300,303,55,343
|
69,2190,2040,1395,134,343,845,1146,919,525,1682,300,2204,2022,1583,428,1180,55,8,235,1894,303,1220
|
2.497417369060405,-0.6372927951239112,-0.5379930941294808,-0.19785570229010588,1.90774847949041,0.97311149261789,0.18492735557866916,-0.03716952921365007,0.11779590878562075,0.5670274774060957,-0.3458054921469844,1.1090521543190752,-0.6372927951239112,-0.51839569402218,-0.2897399955466822,0.7604719773481496,-0.05473421435229654,2.6994624661868474,3.724959724908723,1.3303143323167068,-0.44085843678176667,1.1090521543190752,-0.07237000350541305
| 2,702
|
Mitochondrial respiratory chain complex assembly
| 10
| 32
| 2.521651
| 0.011681
|
Q9P0J0,Q9Y6M9,Q6DKK2,Q86Y39,Q69YU5,Q15070,Q9Y2R0,O96000,O95831,O43676
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
132,133,204,335,46,110,21,119,313,30
|
2638,30,1366,2389,1272,1369,497,1785,471,724,2009,313,119,2517,1613,1583,110,1844,1381,46,204,358,335,1358,624,1163,1523,132,1594,21,690,133
|
-1.472951143850942,3.08995471113118,-0.17970735210207034,-0.8217731668728108,-0.1257092085342695,-0.17970735210207034,0.6124633021363719,-0.4025919634436768,0.672293189318447,0.2999454932185619,-0.51839569402218,1.055211388917935,1.9730395335085762,-1.0141164567184937,-0.30834940175024095,-0.2897399955466822,2.079509582008797,-0.4216838952161537,-0.17970735210207034,2.865701135235128,1.442770611622072,0.9314434222343889,1.0006594538170546,-0.16163385385214332,0.42772059381643684,-0.03716952921365007,-0.2527554805154473,1.9187055275737044,-0.2897399955466822,3.2938193341266992,0.3483101035432623,1.9187055275737044
| 2,702
|
Cholesterol binding
| 8
| 12
| 2.521531
| 0.011685
|
O75477,O15118,Q14108,P61916,P21796,P45880,O94905,P30536
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,69,8,300,15,16,180,151
|
69,192,180,1828,15,1794,151,16,300,8,2332,310
|
2.497417369060405,1.4917673289663298,1.5641657435116996,-0.4216838952161537,3.558604191488058,-0.4025919634436768,1.7738458790955642,3.515789489534347,1.1090521543190752,3.724959724908723,-0.759434892091634,1.0822196248016487
| 2,702
|
Inorganic anion transmembrane transporter activity
| 11
| 20
| 2.514138
| 0.011932
|
P33527,P04920,O15439,Q9Y277,Q9BXP2,Q9UBX3,P21796,P45880,Q9C0H2,P51790,P51798
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
352,484,422,232,528,109,15,16,20,185,248
|
2036,422,531,484,15,352,16,185,248,1020,730,2109,2231,1052,528,20,109,232,2460,840
|
-0.5379930941294808,0.7749899149252996,0.5517730351345772,0.6424844207170954,3.558604191488058,0.9453792994602913,3.515789489534347,1.5281289711930328,1.2793186260964378,0.04960511328482398,0.2999454932185619,-0.5774483420396528,-0.6574202145206469,0.03238835570877815,0.5670274774060957,3.3618378249093492,2.0899995453915405,1.3429641997032904,-0.9062528889503797,0.20154814096271612
| 2,702
|
Regulation of steroid biosynthetic process
| 7
| 10
| 2.510064
| 0.012071
|
O75477,P16435,Q6P1A2,O94905,Q13510,P30536,Q9UBM7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
192,258,212,180,55,151,153
|
192,180,363,258,151,55,1347,212,153,911
|
1.4917673289663298,1.5641657435116996,0.9174606497851514,1.240649509692531,1.7738458790955642,2.6994624661868474,-0.16163385385214332,1.4056301198534875,1.7510836692846126,0.13467692383293534
| 2,702
|
Mitochondrial transmembrane transport
| 18
| 46
| 2.504017
| 0.012279
|
O14925,Q99595,Q9BPX6,Q6P4A7,O43772,Q15388,Q9Y619,O75027,P21796,P12236,O95202,Q8WWC4,Q9H2D1,O75964,P24539,O95831,Q9BQT8,P23786
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,1,257,259,162,295,351,394,15,457,241,438,51,117,374,313,93,63
|
160,648,162,394,1712,989,2070,117,1673,241,966,313,692,856,818,2125,779,457,15,63,374,969,748,2469,642,475,1122,295,930,259,697,2456,438,2270,809,1,257,93,624,51,1133,871,645,559,660,351
|
1.7051658996048906,0.38025187320722004,1.6820076128894363,0.8468333255500231,-0.3646533883592373,0.0667537675442864,-0.5576770803133537,1.9838171226896273,-0.3458054921469844,1.3048961711518003,0.08383480077369695,1.055211388917935,0.33224923450336813,0.1682421911682641,0.20154814096271612,-0.5973075767254589,0.2345983492140732,0.701892290350493,3.558604191488058,2.5721316468788222,0.8893532800594045,0.08383480077369695,0.2673963211845321,-0.9276215217752557,0.39613357596639254,0.672293189318447,-0.019675434888960938,1.122403168752099,0.11779590878562075,1.240649509692531,0.33224923450336813,-0.9062528889503797,0.7459035635880372,-0.6979483260765379,0.2181049920661174,4.023672847582024,1.2535798932893194,2.2440618128355347,0.42772059381643684,2.822658973915516,-0.019675434888960938,0.1682421911682641,0.39613357596639254,0.5210982679469837,0.38025187320722004,0.9592685631657338
| 2,702
|
Glycoside hydrolase superfamily [IPR017853]
| 7
| 15
| 2.496108
| 0.012556
|
P10253,P16278,P04062,P06280,P54802,O60502,P06865
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
196,36,134,104,77,78,253
|
78,134,817,104,253,675,1329,343,196,36,1173,77,1892,466,1264
|
2.4019310104088376,1.90774847949041,0.20154814096271612,2.1316806866838474,1.2664695220524946,0.3483101035432623,-0.16163385385214332,0.97311149261789,1.4795736761747307,3.000210798187082,-0.05473421435229654,2.4115869799105853,-0.44085843678176667,0.701892290350493,-0.10785697374131768
| 2,702
|
Copii coated er to golgi transport vesicle
| 9
| 29
| 2.495723
| 0.01257
|
Q7Z7H5,Q13190,P10321,Q9Y282,Q9BVK6,O95070,Q15363,Q9Y3B3,Q9UBV8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
194,323,326,45,175,269,111,150,190
|
1634,1710,1919,550,943,269,1750,372,2099,326,879,614,2076,825,541,323,111,1285,769,1692,194,1103,175,635,190,45,939,150,913
|
-0.3270376997249967,-0.3646533883592373,-0.46011623230476806,0.5210982679469837,0.10084869034597146,1.188515758083854,-0.3835820044684915,0.8893532800594045,-0.5774483420396528,1.0143650321652233,0.15149219850709802,0.42772059381643684,-0.5576770803133537,0.20154814096271612,0.536463418458696,1.028025369515471,2.079509582008797,-0.1257092085342695,0.25102864836853117,-0.3458054921469844,1.4917673289663298,-0.0022514235063176217,1.5998828218041645,0.411956352337547,1.5160447795129783,2.874250799697163,0.11779590878562075,1.7851784018367542,0.13467692383293534
| 2,702
|
Abnormal biliary tract morphology
| 11
| 21
| 2.483981
| 0.012992
|
Q9UJW0,P04062,Q10713,Q14108,Q14739,P50542,P07602,Q9NZJ7,Q9NSD9,Q5XKP0,P09601
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
331,134,453,8,235,490,13,336,303,371,86
|
531,967,134,13,86,2465,2449,2074,490,1682,453,1180,8,235,371,1968,303,336,331,1594,1220
|
0.5517730351345772,0.08383480077369695,1.90774847949041,3.6358051961034,2.2741564208043514,-0.9276215217752557,-0.9062528889503797,-0.5576770803133537,0.6275005747563835,-0.3458054921469844,0.7166140404526318,-0.05473421435229654,3.724959724908723,1.3303143323167068,0.9034306979462009,-0.4794579332236154,1.1090521543190752,1.0006594538170546,1.0143650321652233,-0.2897399955466822,-0.07237000350541305
| 2,702
|
Hormone metabolic process
| 10
| 26
| 2.483939
| 0.012994
|
Q9HB40,P42892,P16435,O75844,O94788,O95470,P05023,Q6NUM9,P30536,Q9UBM7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,89,258,67,226,107,363,245,151,153
|
1033,67,226,107,363,2536,2319,258,151,89,2541,1682,1255,1185,370,245,714,2499,1103,1385,2524,32,1996,153,2033,1219
|
0.03238835570877815,2.525606359287873,1.3555748844625495,2.0899995453915405,0.9174606497851514,-1.0579885203161268,-0.759434892091634,1.240649509692531,1.7738458790955642,2.254119276071687,-1.0579885203161268,-0.3458054921469844,-0.10785697374131768,-0.05473421435229654,0.9034306979462009,1.2921274336650987,0.31612783470675104,-0.9706631654422068,-0.0022514235063176217,-0.17970735210207034,-1.0141164567184937,3.0494299565613403,-0.4988841983587244,1.7510836692846126,-0.51839569402218,-0.07237000350541305
| 2,702
|
Steroid metabolism
| 10
| 22
| 2.481243
| 0.013093
|
O75477,O15118,P04062,Q16850,Q14739,Q15392,P37268,O94905,Q15800,Q9UBM7
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
192,69,134,139,235,142,147,180,283,153
|
69,192,1427,180,2529,134,694,2345,147,300,1932,2225,2520,235,2228,142,1963,283,139,2524,153,1564
|
2.497417369060405,1.4917673289663298,-0.21607946299314143,1.5641657435116996,-1.0359996897457213,1.90774847949041,0.33224923450336813,-0.7801186405050577,1.7964787566429434,1.1090521543190752,-0.46011623230476806,-0.6574202145206469,-1.0141164567184937,1.3303143323167068,-0.6574202145206469,1.8301884436274014,-0.4794579332236154,1.148975957368919,1.8413617509235753,-1.0141164567184937,1.7510836692846126,-0.2712088850102407
| 2,702
|
Juvenile onset
| 14
| 38
| 2.477771
| 0.013221
|
P16278,O15118,Q16531,P07196,P06280,P51798,P41440,P54802,P50402,Q9NR77,Q9NR50,Q13510,Q14566,O14773
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
36,69,100,364,104,248,271,77,338,115,182,55,186,157
|
157,69,394,2244,967,1921,104,725,364,36,1574,1015,878,525,1335,271,2470,2643,338,615,2281,248,77,1338,750,1842,454,55,2302,186,100,1383,657,1521,182,115,2273,1220
|
1.7166949344659548,2.497417369060405,0.8468333255500231,-0.6776384784971092,0.08383480077369695,-0.46011623230476806,2.1316806866838474,0.2999454932185619,0.9174606497851514,3.000210798187082,-0.2897399955466822,0.04960511328482398,0.15149219850709802,0.5670274774060957,-0.16163385385214332,1.188515758083854,-0.9276215217752557,-1.497135064240729,0.9869083646757261,0.42772059381643684,-0.7183505049899396,1.2793186260964378,2.4115869799105853,-0.16163385385214332,0.2673963211845321,-0.4216838952161537,0.7166140404526318,2.6994624661868474,-0.7388457718106729,1.5281289711930328,2.1626525950929136,-0.17970735210207034,0.38025187320722004,-0.2527554805154473,1.5641657435116996,2.015974080477711,-0.6979483260765379,-0.07237000350541305
| 2,702
|
Hydrolase activity acting on glycosyl bonds
| 10
| 25
| 2.470264
| 0.013501
|
P10253,P16278,P04062,P06280,P54802,O60502,O75503,P17900,P08236,P06865
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
196,36,134,104,77,78,247,82,343,253
|
2685,703,78,247,134,817,104,253,675,343,196,2161,36,82,738,2373,664,1173,77,765,1584,1892,1808,466,360
|
-2.345009462881344,0.31612783470675104,2.4019310104088376,1.2793186260964378,1.90774847949041,0.20154814096271612,2.1316806866838474,1.2664695220524946,0.3483101035432623,0.97311149261789,1.4795736761747307,-0.6172554898593413,3.000210798187082,2.333654152549082,0.28370179506564897,-0.8008978009850447,0.36431084877418707,-0.05473421435229654,2.4115869799105853,0.25102864836853117,-0.2897399955466822,-0.44085843678176667,-0.4025919634436768,0.701892290350493,0.9314434222343889
| 2,702
|
Alcohol binding
| 8
| 14
| 2.461167
| 0.013849
|
O75477,O15118,Q14108,P61916,P21796,P45880,O94905,P30536
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,69,8,300,15,16,180,151
|
702,69,192,180,1828,15,1794,2395,151,16,300,8,2332,310
|
0.31612783470675104,2.497417369060405,1.4917673289663298,1.5641657435116996,-0.4216838952161537,3.558604191488058,-0.4025919634436768,-0.8217731668728108,1.7738458790955642,3.515789489534347,1.1090521543190752,3.724959724908723,-0.759434892091634,1.0822196248016487
| 2,702
|
Regulation of steroid metabolic process
| 7
| 13
| 2.454488
| 0.014109
|
O75477,P16435,Q6P1A2,O94905,Q13510,P30536,Q9UBM7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
192,258,212,180,55,151,153
|
192,180,363,258,151,860,55,1347,1348,212,153,911,2033
|
1.4917673289663298,1.5641657435116996,0.9174606497851514,1.240649509692531,1.7738458790955642,0.1682421911682641,2.6994624661868474,-0.16163385385214332,-0.16163385385214332,1.4056301198534875,1.7510836692846126,0.13467692383293534,-0.51839569402218
| 2,702
|
secondary carrier transporter
| 6
| 15
| 2.449285
| 0.014314
|
Q96ES6,Q6NT16,Q9UBX3,O95202,Q8TB61,Q9BQT8
|
Functions
|
Panther Protein class
|
panther_protein_class
|
169,44,109,241,152,93
|
264,989,241,484,1020,44,1514,152,169,93,528,109,645,812,840
|
1.2146655480675908,0.0667537675442864,1.3048961711518003,0.6424844207170954,0.04960511328482398,2.88278106126926,-0.2527554805154473,1.7738458790955642,1.6235191019297979,2.2440618128355347,0.5670274774060957,2.0899995453915405,0.39613357596639254,0.2181049920661174,0.20154814096271612
| 2,702
|
Vacuolar lumen
| 32
| 60
| 2.445803
| 0.014453
|
P04062,Q14108,P07602,P38571,P07900,O00560,P50897,Q13217,Q8NHP8,P15586,O14773,P16278,P07437,O00584,P61916,Q99538,P68371,Q13510,P38435,P11117,P10253,P10619,Q9BTY2,P54802,Q9NZJ7,P17900,Q8IV08,P08236,Q92820,P06280,Q9H7Z7,P06865
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
134,8,13,525,523,521,22,407,26,280,157,36,291,170,300,179,311,55,183,65,196,72,466,77,336,82,85,343,480,104,378,253
|
521,170,2685,157,531,2529,134,817,104,253,1603,291,13,675,523,343,196,72,65,1331,693,280,36,82,1796,2374,183,525,1176,22,2135,1876,1279,77,1877,2377,300,311,974,2427,1760,407,55,8,1345,85,1482,26,480,850,2404,670,179,1561,466,1264,378,2310,336,1861
|
0.5670274774060957,1.6117183489592206,-2.345009462881344,1.7166949344659548,0.5517730351345772,-1.0359996897457213,1.90774847949041,0.20154814096271612,2.1316806866838474,1.2664695220524946,-0.30834940175024095,1.122403168752099,3.6358051961034,0.3483101035432623,0.5670274774060957,0.97311149261789,1.4795736761747307,2.469019679033845,2.5349567864503544,-0.16163385385214332,0.33224923450336813,1.148975957368919,3.000210798187082,2.333654152549082,-0.4025919634436768,-0.8008978009850447,1.5521892607638046,0.5670274774060957,-0.05473421435229654,3.2708634537820394,-0.5973075767254589,-0.44085843678176667,-0.1257092085342695,2.4115869799105853,-0.44085843678176667,-0.8008978009850447,1.1090521543190752,1.06873759915191,0.08383480077369695,-0.8638157361636718,-0.3835820044684915,0.8182439888074761,2.6994624661868474,3.724959724908723,-0.16163385385214332,2.2841363418193175,-0.23437919882369965,3.224517506261788,0.6574151799611627,0.18492735557866916,-0.8217731668728108,0.36431084877418707,1.5761067056736178,-0.2712088850102407,0.701892290350493,-0.10785697374131768,0.8893532800594045,-0.7388457718106729,1.0006594538170546,-0.4216838952161537
| 2,702
|
Exocytic vesicle
| 7
| 31
| 2.437248
| 0.0148
|
O43760,Q9BVK6,Q92542,Q9BT78,P50897,P51790,P11279
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
70,175,211,148,22,185,221
|
744,1116,511,70,1037,795,221,737,1647,2373,803,22,1336,2507,185,1929,1838,592,975,1652,234,1961,864,928,429,462,211,1102,148,175,868
|
0.2673963211845321,-0.019675434888960938,0.5822271013569861,2.4879747979964018,0.03238835570877815,0.2181049920661174,1.3806795740768194,0.28370179506564897,-0.3270376997249967,-0.8008978009850447,0.2181049920661174,3.2708634537820394,-0.16163385385214332,-0.9923379139698841,1.5281289711930328,-0.46011623230476806,-0.4216838952161537,0.4590750194134483,0.08383480077369695,-0.3270376997249967,1.3303143323167068,-0.4794579332236154,0.1682421911682641,0.11779590878562075,0.7604719773481496,0.701892290350493,1.4180481184366847,-0.0022514235063176217,1.7964787566429434,1.5998828218041645,0.1682421911682641
| 2,702
|
Intrinsic component of golgi membrane
| 6
| 10
| 2.427088
| 0.015221
|
Q8N2H4,Q9Y282,O95070,P98194,O43505,Q8TB61
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
128,45,269,369,149,152
|
1298,1140,149,269,369,1043,424,128,152,45
|
-0.1436346549150024,-0.03716952921365007,1.7851784018367542,1.188515758083854,0.9034306979462009,0.03238835570877815,0.7749899149252996,1.9405289301526898,1.7738458790955642,2.874250799697163
| 2,702
|
Neuromuscular process
| 13
| 25
| 2.416888
| 0.015654
|
Q14203,P78417,O75844,P04062,Q6Y7W6,P10253,P07196,Q8N0X7,P50542,Q7Z406,P17900,P42345,O14773
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
643,418,67,134,556,196,364,494,490,620,82,532,157
|
157,2006,1638,67,134,364,675,196,1038,82,1276,532,1121,1800,490,2263,418,643,928,556,620,1897,494,1211,1105
|
1.7166949344659548,-0.51839569402218,-0.3270376997249967,2.525606359287873,1.90774847949041,0.9174606497851514,0.3483101035432623,1.4795736761747307,0.03238835570877815,2.333654152549082,-0.1257092085342695,0.5517730351345772,-0.019675434888960938,-0.4025919634436768,0.6275005747563835,-0.6979483260765379,0.7894576895397357,0.39613357596639254,0.11779590878562075,0.5210982679469837,0.42772059381643684,-0.44085843678176667,0.6275005747563835,-0.07237000350541305,-0.0022514235063176217
| 2,702
|
Intrinsic component of mitochondrial membrane
| 25
| 44
| 2.409823
| 0.01596
|
Q99595,Q9BPX6,Q6P4A7,Q9H3K2,Q9Y4W6,Q9H9P8,Q9BUR5,Q9Y2R0,Q8IWA4,Q6UXV4,O14925,Q15388,Q9Y512,Q13505,Q9HC21,Q8NE86,P57105,Q16134,Q9NX63,Q9UG56,Q16891,Q15070,Q5XKP0,O75880,O75431
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,257,259,391,660,658,276,21,544,413,160,295,690,42,432,697,452,333,341,628,493,110,371,497,252
|
160,252,497,1673,966,692,779,857,2539,452,1122,42,110,295,333,2354,493,1313,371,259,413,544,866,2269,697,1161,2270,809,1,257,732,276,868,391,1133,658,432,872,341,628,1858,21,660,690
|
1.7051658996048906,1.2664695220524946,0.6124633021363719,-0.3458054921469844,0.08383480077369695,0.33224923450336813,0.2345983492140732,0.1682421911682641,-1.0579885203161268,0.7166140404526318,-0.019675434888960938,2.9082562157141907,2.079509582008797,1.122403168752099,1.0006594538170546,-0.7801186405050577,0.6275005747563835,-0.1436346549150024,0.9034306979462009,1.240649509692531,0.8038756116143992,0.536463418458696,0.1682421911682641,-0.6979483260765379,0.33224923450336813,-0.03716952921365007,-0.6979483260765379,0.2181049920661174,4.023672847582024,1.2535798932893194,0.2999454932185619,1.1753780817167876,0.1682421911682641,0.8610548868787217,-0.019675434888960938,0.38025187320722004,0.7604719773481496,0.1682421911682641,0.9869083646757261,0.42772059381643684,-0.4216838952161537,3.2938193341266992,0.38025187320722004,0.3483101035432623
| 2,702
|
Membrane protein proteolysis
| 7
| 13
| 2.409024
| 0.015995
|
Q9NZ08,Q8TCT9,Q9Y5X1,Q92542,Q16740,O43847,Q8TCT8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,168,237,211,60,318,191
|
318,1015,375,803,902,60,191,168,211,99,1825,660,237
|
1.0416407333608675,0.04960511328482398,0.8893532800594045,0.2181049920661174,0.13467692383293534,2.6180971611507324,1.503924297502507,1.6352852637773565,1.4180481184366847,2.1831648884950323,-0.4025919634436768,0.38025187320722004,1.3303143323167068
| 2,702
|
Carbohydrate derivative transport
| 10
| 18
| 2.407486
| 0.016063
|
Q6NUK1,O15439,O00400,Q8WTV0,P61916,P07602,Q9NZJ7,P41440,Q9HC21,Q8TB61
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
419,422,264,202,300,13,336,271,432,152
|
1298,264,422,736,856,13,779,457,271,300,631,419,152,2231,202,558,432,336
|
-0.1436346549150024,1.2146655480675908,0.7749899149252996,0.28370179506564897,0.1682421911682641,3.6358051961034,0.2345983492140732,0.701892290350493,1.188515758083854,1.1090521543190752,0.411956352337547,0.7894576895397357,1.7738458790955642,-0.6574202145206469,1.4550755191396691,0.5210982679469837,0.7604719773481496,1.0006594538170546
| 2,702
|
Abnormality of pulmonary circulation
| 10
| 26
| 2.402433
| 0.016286
|
O75844,Q9NZ08,P04062,Q14108,P31749,Q8IZA0,P00403,P20674,O96000,P51798
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
67,99,134,8,365,209,114,405,119,248
|
2674,67,1395,119,114,967,134,405,2408,1085,969,365,2278,1064,248,1613,1069,8,1435,1258,419,209,1160,1261,2682,99
|
-1.9820894298789196,2.525606359287873,-0.19785570229010588,1.9730395335085762,2.015974080477711,0.08383480077369695,1.90774847949041,0.8182439888074761,-0.8427455410647996,-0.0022514235063176217,0.08383480077369695,0.9174606497851514,-0.7183505049899396,0.015103007549675692,1.2793186260964378,-0.30834940175024095,0.015103007549675692,3.724959724908723,-0.21607946299314143,-0.10785697374131768,0.7894576895397357,1.4304282132683406,-0.03716952921365007,-0.10785697374131768,-2.2021520177049108,2.1831648884950323
| 2,702
|
Lipid droplet
| 8
| 27
| 2.401379
| 0.016333
|
Q99720,O43760,Q8NF37,Q8NBX0,Q9H6V9,P48449,Q9H8H3,Q07065
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
3,70,103,112,18,242,379,249
|
2005,70,1599,723,1674,2529,1601,1603,242,1757,1336,572,1877,387,249,1963,494,112,103,1128,850,3,18,379,1293,2094,1863
|
-0.51839569402218,2.4879747979964018,-0.30834940175024095,0.2999454932185619,-0.3458054921469844,-1.0359996897457213,-0.30834940175024095,-0.30834940175024095,1.3048961711518003,-0.3835820044684915,-0.16163385385214332,0.4901999107033141,-0.44085843678176667,0.8610548868787217,1.2793186260964378,-0.4794579332236154,0.6275005747563835,2.0478703095158535,2.1420319569801767,-0.019675434888960938,0.18492735557866916,3.979807696470662,3.4212553830067804,0.8893532800594045,-0.1257092085342695,-0.5576770803133537,-0.4216838952161537
| 2,702
|
Endoplasmic reticulum golgi intermediate compartment
| 17
| 41
| 2.40104
| 0.016349
|
Q12907,Q7Z7H5,Q13190,P24390,Q10472,Q9Y282,Q9BVK6,O95070,O75396,O15260,Q15363,Q02818,P80303,Q9Y3B3,Q8IUR0,Q15904,P07237
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
541,194,323,10,491,45,175,269,550,207,111,113,53,150,469,501,381
|
1140,207,988,550,269,381,1955,10,2346,2299,879,614,1432,572,2047,1279,728,53,113,491,541,323,784,1471,111,501,1692,194,469,1128,1969,774,175,1997,1323,1912,45,939,150,721,913
|
-0.03716952921365007,1.4304282132683406,0.0667537675442864,0.5210982679469837,1.188515758083854,0.8752281069462309,-0.4794579332236154,3.6703575558394306,-0.7801186405050577,-0.7388457718106729,0.15149219850709802,0.42772059381643684,-0.21607946299314143,0.4901999107033141,-0.5379930941294808,-0.1257092085342695,0.2999454932185619,2.743923191833523,2.026634938769209,0.6275005747563835,0.536463418458696,1.028025369515471,0.2345983492140732,-0.23437919882369965,2.079509582008797,0.6124633021363719,-0.3458054921469844,1.4917673289663298,0.6871187825431656,-0.019675434888960938,-0.4794579332236154,0.25102864836853117,1.5998828218041645,-0.4988841983587244,-0.1436346549150024,-0.44085843678176667,2.874250799697163,0.11779590878562075,1.7851784018367542,0.31612783470675104,0.13467692383293534
| 2,702
|
External side of plasma membrane
| 10
| 20
| 2.388099
| 0.016936
|
P42892,P02786,Q9H2H9,P41440,P07237,P08183,P51790,O96005,P00813,P11279
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
89,322,198,271,381,84,185,122,155,221
|
422,705,122,1675,155,322,894,1170,381,84,221,2536,2346,271,89,1064,185,2586,731,198
|
0.7749899149252996,0.31612783470675104,1.9622324023613926,-0.3458054921469844,1.7281907938755132,1.028025369515471,0.13467692383293534,-0.05473421435229654,0.8752281069462309,2.3040194739784066,1.3806795740768194,-1.0579885203161268,-0.7801186405050577,1.188515758083854,2.254119276071687,0.015103007549675692,1.5281289711930328,-1.169549198546752,0.2999454932185619,1.4795736761747307
| 2,702
|
Increased bone mineral density
| 7
| 23
| 2.383192
| 0.017163
|
P04062,Q14108,Q14739,P54802,Q15392,P51798,P48651
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
134,8,235,77,142,248,124
|
2574,967,134,877,1274,2408,1923,1609,124,248,77,1877,1931,1042,515,8,235,829,142,1474,1859,720,350
|
-1.1470183659657167,0.08383480077369695,1.90774847949041,0.15149219850709802,-0.1257092085342695,-0.8427455410647996,-0.46011623230476806,-0.30834940175024095,1.9622324023613926,1.2793186260964378,2.4115869799105853,-0.44085843678176667,-0.46011623230476806,0.03238835570877815,0.5822271013569861,3.724959724908723,1.3303143323167068,0.20154814096271612,1.8301884436274014,-0.23437919882369965,-0.4216838952161537,0.31612783470675104,0.9592685631657338
| 2,702
|
Er nucleus signaling pathway
| 6
| 13
| 2.373041
| 0.017642
|
O75477,P16615,Q15363,O94905,Q6P1A2,Q96A33
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
192,292,111,180,212,250
|
192,180,917,1013,292,1118,382,111,212,250,1852,1668,1194
|
1.4917673289663298,1.5641657435116996,0.11779590878562075,0.04960511328482398,1.122403168752099,-0.019675434888960938,0.8752281069462309,2.079509582008797,1.4056301198534875,1.2793186260964378,-0.4216838952161537,-0.3270376997249967,-0.05473421435229654
| 2,702
|
Cherry red spot of the macula
| 6
| 9
| 2.371519
| 0.017715
|
P16278,P10619,P07602,P17900,Q13510,P06865
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
36,72,13,82,55,253
|
253,13,675,72,2012,36,82,55,336
|
1.2664695220524946,3.6358051961034,0.3483101035432623,2.469019679033845,-0.51839569402218,3.000210798187082,2.333654152549082,2.6994624661868474,1.0006594538170546
| 2,702
|
Steroid biosynthetic process
| 16
| 39
| 2.367898
| 0.017889
|
O75477,P16435,Q16850,Q14739,Q14534,Q15392,P05023,P48449,P37268,O94905,Q13510,Q15800,P30536,Q9H4L5,Q9UBM7,Q6P1A2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
192,258,139,235,173,142,363,242,147,180,55,283,151,310,153,212
|
192,1427,180,2529,363,1459,694,2319,258,582,1794,2345,1086,151,147,2321,242,1876,2225,55,2520,173,235,2228,142,1347,1185,1963,283,139,370,212,2499,834,2524,1028,310,153,911
|
1.4917673289663298,-0.21607946299314143,1.5641657435116996,-1.0359996897457213,0.9174606497851514,-0.23437919882369965,0.33224923450336813,-0.759434892091634,1.240649509692531,0.4746659679952571,-0.4025919634436768,-0.7801186405050577,-0.0022514235063176217,1.7738458790955642,1.7964787566429434,-0.759434892091634,1.3048961711518003,-0.44085843678176667,-0.6574202145206469,2.6994624661868474,-1.0141164567184937,1.5998828218041645,1.3303143323167068,-0.6574202145206469,1.8301884436274014,-0.16163385385214332,-0.05473421435229654,-0.4794579332236154,1.148975957368919,1.8413617509235753,0.9034306979462009,1.4056301198534875,-0.9706631654422068,0.20154814096271612,-1.0141164567184937,0.04960511328482398,1.0822196248016487,1.7510836692846126,0.13467692383293534
| 2,702
|
Rac2 gtpase cycle
| 7
| 32
| 2.358574
| 0.018345
|
P02786,Q86XL3,Q13505,Q14739,Q9H0H5,O15173,Q7L576
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
322,102,42,235,239,83,316
|
83,1642,322,1170,1038,1063,526,1278,879,338,1336,1233,2137,1884,1123,42,977,2054,235,1513,956,1348,316,102,684,1107,239,2065,1858,569,720,690
|
2.3040194739784066,-0.3270376997249967,1.028025369515471,-0.05473421435229654,0.03238835570877815,0.015103007549675692,0.5670274774060957,-0.1257092085342695,0.15149219850709802,0.9869083646757261,-0.16163385385214332,-0.09007741527544748,-0.5973075767254589,-0.44085843678176667,-0.019675434888960938,2.9082562157141907,0.08383480077369695,-0.5379930941294808,1.3303143323167068,-0.2527554805154473,0.10084869034597146,-0.16163385385214332,1.055211388917935,2.1420319569801767,0.3483101035432623,-0.0022514235063176217,1.3176250631188255,-0.5379930941294808,-0.4216838952161537,0.5056772207789714,0.31612783470675104,0.3483101035432623
| 2,702
|
Protein transmembrane transport
| 6
| 22
| 2.35221
| 0.018662
|
Q9NS69,Q99595,Q15388,O14925,Q15629,O95831
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,295,160,64,313
|
160,648,319,1673,313,692,2125,1038,614,490,2577,2351,1405,1687,295,64,930,1,624,871,0,636
|
1.7051658996048906,0.38025187320722004,1.0416407333608675,-0.3458054921469844,1.055211388917935,0.33224923450336813,-0.5973075767254589,0.03238835570877815,0.42772059381643684,0.6275005747563835,-1.1470183659657167,-0.7801186405050577,-0.19785570229010588,-0.3458054921469844,1.122403168752099,2.5628717612311127,0.11779590878562075,4.023672847582024,0.42772059381643684,0.1682421911682641,4.339098672789817,0.411956352337547
| 2,702
|
Cholesterol biosynthesis
| 8
| 15
| 2.343955
| 0.01908
|
Q9BWD1,Q14739,Q16850,Q14534,Q15392,P48449,P37268,Q9UBM7
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
6,235,139,173,142,242,147,153
|
1427,694,147,242,2225,2520,173,235,2228,142,1963,283,139,6,153
|
-0.21607946299314143,0.33224923450336813,1.7964787566429434,1.3048961711518003,-0.6574202145206469,-1.0141164567184937,1.5998828218041645,1.3303143323167068,-0.6574202145206469,1.8301884436274014,-0.4794579332236154,1.148975957368919,1.8413617509235753,3.805333958926554,1.7510836692846126
| 2,702
|
Sulfur compound transmembrane transporter activity
| 6
| 9
| 2.330705
| 0.019769
|
P33527,Q70HW3,O15439,O00400,Q9UBX3,Q8TB61
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
352,5,422,264,109,152
|
264,422,352,1020,5,152,432,109,812
|
1.2146655480675908,0.7749899149252996,0.9453792994602913,0.04960511328482398,3.857928935292173,1.7738458790955642,0.7604719773481496,2.0899995453915405,0.2181049920661174
| 2,702
|
Monovalent inorganic cation homeostasis
| 12
| 24
| 2.330034
| 0.019804
|
Q96PU5,P04920,Q9Y487,Q93050,Q9BXP2,P05023,Q9Y5X3,Q92544,Q15904,P50897,P51790,O75503
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
98,484,37,40,528,363,238,566,501,22,185,247
|
247,2530,484,363,1457,818,1924,1796,22,1336,185,2223,592,501,566,40,98,528,1912,1112,37,238,2460,840
|
1.2793186260964378,-1.0359996897457213,0.6424844207170954,0.9174606497851514,-0.23437919882369965,0.20154814096271612,-0.46011623230476806,-0.4025919634436768,3.2708634537820394,-0.16163385385214332,1.5281289711930328,-0.6574202145206469,0.4590750194134483,0.6124633021363719,0.5056772207789714,2.941956184280774,2.1831648884950323,0.5670274774060957,-0.44085843678176667,-0.0022514235063176217,2.975355597745126,1.3303143323167068,-0.9062528889503797,0.20154814096271612
| 2,702
|
Glycosaminoglycan metabolism
| 6
| 12
| 2.324424
| 0.020103
|
P16278,P54802,O43505,Q8TB61,P15586,P06865
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
36,77,149,152,280,253
|
1865,149,1225,253,675,343,280,36,77,1158,152,1912
|
-0.44085843678176667,1.7851784018367542,-0.09007741527544748,1.2664695220524946,0.3483101035432623,0.97311149261789,1.148975957368919,3.000210798187082,2.4115869799105853,-0.03716952921365007,1.7738458790955642,-0.44085843678176667
| 2,702
|
Organic acid transport
| 13
| 41
| 2.313383
| 0.020702
|
P33527,O43772,Q6P4A7,Q9H2H9,Q9Y619,P31749,P41440,Q9UBX3,Q9H2D1,P08183,P53985,Q9BQT8,P23786
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
352,162,259,198,351,365,271,109,51,84,244,93,63
|
422,162,736,989,942,966,1674,2391,894,1170,1869,84,1329,539,2465,1085,63,1086,2395,365,1576,352,271,803,244,2427,1020,1312,1514,259,2231,809,508,93,51,198,1133,109,645,812,351
|
0.7749899149252996,1.6820076128894363,0.28370179506564897,0.0667537675442864,0.10084869034597146,0.08383480077369695,-0.3458054921469844,-0.8217731668728108,0.13467692383293534,-0.05473421435229654,-0.44085843678176667,2.3040194739784066,-0.16163385385214332,0.536463418458696,-0.9276215217752557,-0.0022514235063176217,2.5721316468788222,-0.0022514235063176217,-0.8217731668728108,0.9174606497851514,-0.2897399955466822,0.9453792994602913,1.188515758083854,0.2181049920661174,1.2921274336650987,-0.8638157361636718,0.04960511328482398,-0.1436346549150024,-0.2527554805154473,1.240649509692531,-0.6574202145206469,0.2181049920661174,0.5973722597638846,2.2440618128355347,2.822658973915516,1.4795736761747307,-0.019675434888960938,2.0899995453915405,0.39613357596639254,0.2181049920661174,0.9592685631657338
| 2,702
|
Membrane protein ectodomain proteolysis
| 6
| 11
| 2.313298
| 0.020706
|
Q9NZ08,Q8TCT9,Q9Y5X1,Q92542,O43847,Q8TCT8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
99,168,237,211,318,191
|
318,1015,375,803,902,191,168,211,99,1825,237
|
1.0416407333608675,0.04960511328482398,0.8893532800594045,0.2181049920661174,0.13467692383293534,1.503924297502507,1.6352852637773565,1.4180481184366847,2.1831648884950323,-0.4025919634436768,1.3303143323167068
| 2,702
|
Transition metal ion transport
| 7
| 12
| 2.305252
| 0.021152
|
Q8NEW0,P02786,Q8N4V1,O75027,P98194,O15173,Q9HD20
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,322,9,394,369,83,56
|
83,394,322,615,369,2053,882,429,9,96,1133,56
|
2.3040194739784066,0.8468333255500231,1.028025369515471,0.42772059381643684,0.9034306979462009,-0.5379930941294808,0.15149219850709802,0.7604719773481496,3.724959724908723,2.223868499779184,-0.019675434888960938,2.690507421713021
| 2,702
|
Liposaccharide metabolic process
| 6
| 12
| 2.304061
| 0.021219
|
P16278,P04062,P06280,Q8NBX0,P17900,Q99805
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
36,134,104,112,82,251
|
134,817,104,253,675,36,82,2614,112,1625,1212,251
|
1.90774847949041,0.20154814096271612,2.1316806866838474,1.2664695220524946,0.3483101035432623,3.000210798187082,2.333654152549082,-1.307106361795847,2.0478703095158535,-0.30834940175024095,-0.07237000350541305,1.2793186260964378
| 2,702
|
Abnormal retinal artery morphology
| 8
| 20
| 2.301388
| 0.02137
|
P16278,P10619,P07602,Q9NZJ7,P17900,Q13510,P06865,Q9Y4P3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
36,72,13,336,82,55,253,350
|
1223,2574,253,13,675,72,2012,36,82,356,1609,2076,1931,55,829,2649,934,336,1859,350
|
-0.09007741527544748,-1.1470183659657167,1.2664695220524946,3.6358051961034,0.3483101035432623,2.469019679033845,-0.51839569402218,3.000210798187082,2.333654152549082,0.9314434222343889,-0.30834940175024095,-0.5576770803133537,-0.46011623230476806,2.6994624661868474,0.20154814096271612,-1.570450064901612,0.11779590878562075,1.0006594538170546,-0.4216838952161537,0.9592685631657338
| 2,702
|
Cation transmembrane transporter activity
| 28
| 68
| 2.301364
| 0.021371
|
Q70HW3,O00400,Q8N4V1,P20674,O43772,Q9Y487,Q93050,Q96ES6,P16615,Q9HC21,Q13423,Q9HD20,P51790,Q9H2H9,Q7KZN9,P13073,P56385,Q9UDW1,P21281,Q9Y619,Q8NEW0,P05023,O95202,P98194,P00403,O75964,P24539,Q96QD8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
5,264,9,405,162,37,40,169,292,432,50,56,185,198,213,337,475,90,472,351,96,363,241,369,114,117,374,508
|
264,162,736,2070,117,241,114,363,1457,856,818,1603,1828,1329,1036,1250,779,337,292,737,405,472,2320,707,374,969,921,748,1577,1927,2469,803,185,642,475,592,1405,369,1122,50,1312,730,5,213,9,697,96,2148,40,2270,169,809,508,558,528,657,198,1133,432,56,90,1112,1194,812,37,734,351,840
|
1.2146655480675908,1.6820076128894363,0.28370179506564897,-0.5576770803133537,1.9838171226896273,1.3048961711518003,2.015974080477711,0.9174606497851514,-0.23437919882369965,0.1682421911682641,0.20154814096271612,-0.30834940175024095,-0.4216838952161537,-0.16163385385214332,0.03238835570877815,-0.10785697374131768,0.2345983492140732,0.9869083646757261,1.122403168752099,0.28370179506564897,0.8182439888074761,0.672293189318447,-0.759434892091634,0.31612783470675104,0.8893532800594045,0.08383480077369695,0.11779590878562075,0.2673963211845321,-0.2897399955466822,-0.46011623230476806,-0.9276215217752557,0.2181049920661174,1.5281289711930328,0.39613357596639254,0.672293189318447,0.4590750194134483,-0.19785570229010588,0.9034306979462009,-0.019675434888960938,2.831306853338417,-0.1436346549150024,0.2999454932185619,3.857928935292173,1.4056301198534875,3.724959724908723,0.33224923450336813,2.223868499779184,-0.5973075767254589,2.941956184280774,-0.6979483260765379,1.6235191019297979,0.2181049920661174,0.5973722597638846,0.5210982679469837,0.5670274774060957,0.38025187320722004,1.4795736761747307,-0.019675434888960938,0.7604719773481496,2.690507421713021,2.254119276071687,-0.0022514235063176217,-0.05473421435229654,0.2181049920661174,2.975355597745126,0.2999454932185619,0.9592685631657338,0.20154814096271612
| 2,702
|
Steroid biosynthesis
| 6
| 10
| 2.299434
| 0.02148
|
Q16850,Q14534,Q15392,P48449,P37268,Q9UBM7
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
139,173,142,242,147,153
|
1427,147,525,242,173,142,1963,283,139,153
|
-0.21607946299314143,1.7964787566429434,0.5670274774060957,1.3048961711518003,1.5998828218041645,1.8301884436274014,-0.4794579332236154,1.148975957368919,1.8413617509235753,1.7510836692846126
| 2,702
|
Hydrolase activity hydrolyzing o glycosyl compounds
| 9
| 18
| 2.298221
| 0.021549
|
P10253,P16278,P04062,P06280,P54802,O60502,P17900,P08236,P06865
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
196,36,134,104,77,78,82,343,253
|
2685,78,134,817,104,253,675,343,196,36,82,1173,77,1584,1892,1808,466,360
|
-2.345009462881344,2.4019310104088376,1.90774847949041,0.20154814096271612,2.1316806866838474,1.2664695220524946,0.3483101035432623,0.97311149261789,1.4795736761747307,3.000210798187082,2.333654152549082,-0.05473421435229654,2.4115869799105853,-0.2897399955466822,-0.44085843678176667,-0.4025919634436768,0.701892290350493,0.9314434222343889
| 2,702
|
Mitochondrial membrane organization
| 19
| 43
| 2.293796
| 0.021802
|
Q9NS69,Q9H3K2,Q9P0J0,P07900,P45880,Q9BUR5,Q6UXV4,O60313,Q13505,Q8WWC4,Q9NX63,Q9Y5J7,O14737,Q16891,P50542,Q15070,O95202,Q5XKP0,O75431
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,391,132,523,16,276,413,416,42,438,341,342,233,493,490,110,241,371,252
|
1031,233,416,252,1673,241,917,856,523,1429,779,857,2585,1678,2103,2539,2321,16,490,1091,42,110,2354,493,930,1313,371,413,544,866,2269,438,276,391,0,872,341,132,1594,660,690,342,612
|
0.03238835570877815,1.3303143323167068,0.7894576895397357,1.2664695220524946,-0.3458054921469844,1.3048961711518003,0.11779590878562075,0.1682421911682641,0.5670274774060957,-0.21607946299314143,0.2345983492140732,0.1682421911682641,-1.169549198546752,-0.3458054921469844,-0.5774483420396528,-1.0579885203161268,-0.759434892091634,3.515789489534347,0.6275005747563835,-0.0022514235063176217,2.9082562157141907,2.079509582008797,-0.7801186405050577,0.6275005747563835,0.11779590878562075,-0.1436346549150024,0.9034306979462009,0.8038756116143992,0.536463418458696,0.1682421911682641,-0.6979483260765379,0.7459035635880372,1.1753780817167876,0.8610548868787217,4.339098672789817,0.1682421911682641,0.9869083646757261,1.9187055275737044,-0.2897399955466822,0.38025187320722004,0.3483101035432623,0.9869083646757261,0.4434266881560912
| 2,702
|
Membrane lipid biosynthetic process
| 7
| 17
| 2.285371
| 0.022291
|
P04062,O95470,Q96G23,Q8NBX0,Q13510,Q99805,Q06136
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
134,107,301,112,55,251,189
|
495,1533,107,134,582,189,55,2614,1313,112,1625,301,1212,251,1165,312,1524
|
0.6124633021363719,-0.2712088850102407,2.0899995453915405,1.90774847949041,0.4746659679952571,1.5160447795129783,2.6994624661868474,-1.307106361795847,-0.1436346549150024,2.0478703095158535,-0.30834940175024095,1.1090521543190752,-0.07237000350541305,1.2793186260964378,-0.03716952921365007,1.06873759915191,-0.2527554805154473
| 2,702
|
Abnormality of the metacarpal bones
| 13
| 34
| 2.285037
| 0.022311
|
Q9BXW9,P16435,P16278,Q32P28,Q14739,P31749,O96028,O95202,P08236,Q9UBM7,P51798,O43924,P48651
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
384,258,36,357,235,365,123,241,343,153,248,27,124
|
27,2433,1141,2390,241,123,343,845,36,258,2408,365,2074,1537,124,248,677,1069,2301,1891,235,1764,711,357,2510,419,2604,1212,384,869,2117,873,153,912
|
3.216736188042297,-0.8849845746322226,-0.03716952921365007,-0.8217731668728108,1.3048961711518003,1.9622324023613926,0.97311149261789,0.18492735557866916,3.000210798187082,1.240649509692531,-0.8427455410647996,0.9174606497851514,-0.5576770803133537,-0.2712088850102407,1.9622324023613926,1.2793186260964378,0.3483101035432623,0.015103007549675692,-0.7388457718106729,-0.44085843678176667,1.3303143323167068,-0.3835820044684915,0.31612783470675104,0.9314434222343889,-0.9923379139698841,0.7894576895397357,-1.2378133956363797,-0.07237000350541305,0.8752281069462309,0.1682421911682641,-0.5774483420396528,0.1682421911682641,1.7510836692846126,0.13467692383293534
| 2,702
|
Cellular monovalent inorganic cation homeostasis
| 10
| 21
| 2.278879
| 0.022674
|
Q96PU5,P04920,Q9Y487,Q93050,P05023,Q92544,Q15904,P50897,P51790,O75503
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
98,484,37,40,363,566,501,22,185,247
|
247,484,363,1457,818,1924,1796,22,1336,185,2223,592,501,566,40,98,1912,1112,37,2460,840
|
1.2793186260964378,0.6424844207170954,0.9174606497851514,-0.23437919882369965,0.20154814096271612,-0.46011623230476806,-0.4025919634436768,3.2708634537820394,-0.16163385385214332,1.5281289711930328,-0.6574202145206469,0.4590750194134483,0.6124633021363719,0.5056772207789714,2.941956184280774,2.1831648884950323,-0.44085843678176667,-0.0022514235063176217,2.975355597745126,-0.9062528889503797,0.20154814096271612
| 2,702
|
Cardiac muscle contraction
| 7
| 19
| 2.273408
| 0.023002
|
P14406,P16615,P05023,P00403,O14949,P13073,Q9UDW1
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
7,292,363,114,116,337,90
|
116,114,363,1457,725,1036,498,2160,1250,337,7,2072,292,405,663,921,2223,1067,90
|
2.00528425298711,2.015974080477711,0.9174606497851514,-0.23437919882369965,0.2999454932185619,0.03238835570877815,0.6124633021363719,-0.6172554898593413,-0.10785697374131768,0.9869083646757261,3.792063109742703,-0.5576770803133537,1.122403168752099,0.8182439888074761,0.36431084877418707,0.11779590878562075,-0.6574202145206469,0.015103007549675692,2.254119276071687
| 2,702
|
Underdeveloped supraorbital ridges
| 8
| 11
| 2.263494
| 0.023605
|
Q6NUK1,P16435,Q08J23,P50542,P98175,P40855,O75381,P52732
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
419,258,130,490,476,314,319,444
|
319,258,1148,314,490,444,476,1042,130,419,584
|
1.0416407333608675,1.240649509692531,-0.03716952921365007,1.055211388917935,0.6275005747563835,0.7312843575943586,0.672293189318447,0.03238835570877815,1.9187055275737044,0.7894576895397357,0.4746659679952571
| 2,702
|
Sulfur compound transport
| 7
| 11
| 2.253703
| 0.024215
|
P33527,Q70HW3,O15439,O00400,Q9UBX3,Q9H0H5,Q8TB61
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
352,5,422,264,109,239,152
|
264,422,352,1020,5,152,2231,239,432,109,812
|
1.2146655480675908,0.7749899149252996,0.9453792994602913,0.04960511328482398,3.857928935292173,1.7738458790955642,-0.6574202145206469,1.3176250631188255,0.7604719773481496,2.0899995453915405,0.2181049920661174
| 2,702
|
Glycerolipid biosynthetic process
| 11
| 35
| 2.250281
| 0.024431
|
Q9NPH0,Q10713,Q16822,Q8NF37,Q8WTV0,O95674,Q9BTU6,Q8NCC3,Q6P1A2,P35790,P48651
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,453,329,103,202,299,431,437,212,59,124
|
2240,702,1083,1674,299,1576,59,1016,124,2427,1615,1069,453,329,1349,212,1157,437,103,202,2478,519,1625,1446,1005,1212,1520,1321,431,2257,4,1109,718,873,628
|
-0.6776384784971092,0.31612783470675104,-0.0022514235063176217,-0.3458054921469844,1.1090521543190752,-0.2897399955466822,2.6180971611507324,0.04960511328482398,1.9622324023613926,-0.8638157361636718,-0.30834940175024095,0.015103007549675692,0.7166140404526318,1.0143650321652233,-0.16163385385214332,1.4056301198534875,-0.03716952921365007,0.7459035635880372,2.1420319569801767,1.4550755191396691,-0.9276215217752557,0.5822271013569861,-0.30834940175024095,-0.21607946299314143,0.0667537675442864,-0.07237000350541305,-0.2527554805154473,-0.1436346549150024,0.7604719773481496,-0.6776384784971092,3.9417705569579184,-0.0022514235063176217,0.31612783470675104,0.1682421911682641,0.42772059381643684
| 2,702
|
Protein localization to mitochondrion
| 17
| 51
| 2.245927
| 0.024709
|
Q9NS69,Q99595,O14925,Q15388,Q9P0J0,Q8N4H5,O14737,P55786,Q9Y6C9,P31749,Q5JRX3,Q15070,Q9Y371,Q8WWC4,Q9Y5J7,P30536,O95831
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,160,295,132,39,233,74,332,365,430,110,307,438,342,151,313
|
735,1031,744,233,160,648,1712,1673,1749,313,692,523,2125,1371,2393,2219,1678,151,1171,365,2103,879,572,1091,74,2140,453,110,295,930,1313,430,2058,39,1161,438,1053,1,547,624,868,871,0,132,1166,1594,307,690,342,612,332
|
0.28370179506564897,0.03238835570877815,0.2673963211845321,1.3303143323167068,1.7051658996048906,0.38025187320722004,-0.3646533883592373,-0.3458054921469844,-0.3835820044684915,1.055211388917935,0.33224923450336813,0.5670274774060957,-0.5973075767254589,-0.17970735210207034,-0.8217731668728108,-0.6574202145206469,-0.3458054921469844,1.7738458790955642,-0.05473421435229654,0.9174606497851514,-0.5774483420396528,0.15149219850709802,0.4901999107033141,-0.0022514235063176217,2.4308266158331455,-0.5973075767254589,0.7166140404526318,2.079509582008797,1.122403168752099,0.11779590878562075,-0.1436346549150024,0.7604719773481496,-0.5379930941294808,2.9503340260738637,-0.03716952921365007,0.7459035635880372,0.03238835570877815,4.023672847582024,0.536463418458696,0.42772059381643684,0.1682421911682641,0.1682421911682641,4.339098672789817,1.9187055275737044,-0.03716952921365007,-0.2897399955466822,1.0956577244042058,0.3483101035432623,0.9869083646757261,0.4434266881560912,1.0143650321652233
| 2,702
|
Phospholipid metabolism
| 10
| 40
| 2.24289
| 0.024904
|
Q9NPH0,Q8NF37,O95674,Q9BTU6,Q8NCC3,Q9NQZ5,Q6P1A2,Q8IV08,P35790,P48651
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
4,103,299,431,437,17,212,85,59,124
|
2240,702,1083,1300,299,2219,1251,1647,59,1463,1016,1174,124,1149,2376,973,1685,1615,1069,453,1313,212,1157,85,1899,565,437,103,519,1005,1520,757,1321,431,2332,4,17,1109,718,628
|
-0.6776384784971092,0.31612783470675104,-0.0022514235063176217,-0.1436346549150024,1.1090521543190752,-0.6574202145206469,-0.10785697374131768,-0.3270376997249967,2.6180971611507324,-0.23437919882369965,0.04960511328482398,-0.05473421435229654,1.9622324023613926,-0.03716952921365007,-0.8008978009850447,0.08383480077369695,-0.3458054921469844,-0.30834940175024095,0.015103007549675692,0.7166140404526318,-0.1436346549150024,1.4056301198534875,-0.03716952921365007,2.2841363418193175,-0.44085843678176667,0.5056772207789714,0.7459035635880372,2.1420319569801767,0.5822271013569861,0.0667537675442864,-0.2527554805154473,0.2673963211845321,-0.1436346549150024,0.7604719773481496,-0.759434892091634,3.9417705569579184,3.4359598674765164,-0.0022514235063176217,0.31612783470675104,0.42772059381643684
| 2,702
|
Steroid metabolic process
| 24
| 58
| 2.241966
| 0.024964
|
P16435,P04062,Q16850,Q9BQE5,Q15392,P37268,Q15800,P30536,Q9UBM7,P61916,Q14534,Q99538,O94905,Q9H4L5,Q13510,P38435,O75477,O15118,Q8WTV0,Q6P1A2,Q14739,O95470,P05023,P48449
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
258,134,139,12,142,147,283,151,153,300,173,179,180,310,55,183,192,69,202,212,235,107,363,242
|
69,192,1427,180,107,2529,134,363,2317,1459,694,2319,258,582,1794,2345,2516,1086,151,147,183,525,2321,242,860,2263,1682,1876,300,1932,2225,1376,55,2520,173,235,2228,142,1347,1185,1963,283,139,370,1348,212,202,2499,834,179,2524,12,1028,310,153,1564,911,2033
|
2.497417369060405,1.4917673289663298,-0.21607946299314143,1.5641657435116996,2.0899995453915405,-1.0359996897457213,1.90774847949041,0.9174606497851514,-0.759434892091634,-0.23437919882369965,0.33224923450336813,-0.759434892091634,1.240649509692531,0.4746659679952571,-0.4025919634436768,-0.7801186405050577,-1.0141164567184937,-0.0022514235063176217,1.7738458790955642,1.7964787566429434,1.5521892607638046,0.5670274774060957,-0.759434892091634,1.3048961711518003,0.1682421911682641,-0.6979483260765379,-0.3458054921469844,-0.44085843678176667,1.1090521543190752,-0.46011623230476806,-0.6574202145206469,-0.17970735210207034,2.6994624661868474,-1.0141164567184937,1.5998828218041645,1.3303143323167068,-0.6574202145206469,1.8301884436274014,-0.16163385385214332,-0.05473421435229654,-0.4794579332236154,1.148975957368919,1.8413617509235753,0.9034306979462009,-0.16163385385214332,1.4056301198534875,1.4550755191396691,-0.9706631654422068,0.20154814096271612,1.5761067056736178,-1.0141164567184937,3.642742245523358,0.04960511328482398,1.0822196248016487,1.7510836692846126,-0.2712088850102407,0.13467692383293534,-0.51839569402218
| 2,702
|
Cytochrome complex
| 6
| 15
| 2.237644
| 0.025244
|
P14406,P00403,O14949,Q7KZN9,P13073,Q9UDW1
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
7,114,116,213,337,90
|
1247,116,114,1036,2160,1250,337,7,2072,405,663,921,213,90,1594
|
-0.10785697374131768,2.00528425298711,2.015974080477711,0.03238835570877815,-0.6172554898593413,-0.10785697374131768,0.9869083646757261,3.792063109742703,-0.5576770803133537,0.8182439888074761,0.36431084877418707,0.11779590878562075,1.4056301198534875,2.254119276071687,-0.2897399955466822
| 2,702
|
Skin nodule
| 7
| 20
| 2.234598
| 0.025444
|
Q9NZ08,P35637,P06280,P16615,P31749,Q9NSE4,Q13510
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
99,328,104,292,365,172,55
|
1826,104,991,292,599,365,1499,328,2568,1064,444,1615,1255,55,769,1160,1209,172,99,720
|
-0.4216838952161537,2.1316806866838474,0.0667537675442864,1.122403168752099,0.4434266881560912,0.9174606497851514,-0.2527554805154473,1.0143650321652233,-1.124597841923488,0.015103007549675692,0.7312843575943586,-0.30834940175024095,-0.10785697374131768,2.6994624661868474,0.25102864836853117,-0.03716952921365007,-0.07237000350541305,1.6117183489592206,2.1831648884950323,0.31612783470675104
| 2,702
|
Ion transport
| 23
| 53
| 2.224941
| 0.026085
|
Q9BPX6,P21796,P45880,Q9C0H2,Q9Y487,Q93050,P16615,P51790,Q9H2H9,P56385,P21281,Q8NEW0,P04920,Q9Y277,P05023,Q9H0H5,O95202,P98194,Q15904,O75964,P24539,P51798,Q96QD8
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
257,15,16,20,37,40,292,185,198,475,472,96,484,232,363,239,241,369,501,117,374,248,508
|
2036,2070,117,241,692,484,363,1457,818,292,737,472,2320,15,707,374,969,748,1577,1927,16,2469,185,248,2223,642,475,592,369,1021,501,730,2109,533,697,96,2231,40,2270,508,1052,257,20,239,198,1112,1194,232,812,37,734,2460,840
|
-0.5379930941294808,-0.5576770803133537,1.9838171226896273,1.3048961711518003,0.33224923450336813,0.6424844207170954,0.9174606497851514,-0.23437919882369965,0.20154814096271612,1.122403168752099,0.28370179506564897,0.672293189318447,-0.759434892091634,3.558604191488058,0.31612783470675104,0.8893532800594045,0.08383480077369695,0.2673963211845321,-0.2897399955466822,-0.46011623230476806,3.515789489534347,-0.9276215217752557,1.5281289711930328,1.2793186260964378,-0.6574202145206469,0.39613357596639254,0.672293189318447,0.4590750194134483,0.9034306979462009,0.04960511328482398,0.6124633021363719,0.2999454932185619,-0.5774483420396528,0.5517730351345772,0.33224923450336813,2.223868499779184,-0.6574202145206469,2.941956184280774,-0.6979483260765379,0.5973722597638846,0.03238835570877815,1.2535798932893194,3.3618378249093492,1.3176250631188255,1.4795736761747307,-0.0022514235063176217,-0.05473421435229654,1.3429641997032904,0.2181049920661174,2.975355597745126,0.2999454932185619,-0.9062528889503797,0.20154814096271612
| 2,702
|
Inorganic molecular entity transmembrane transporter activity
| 34
| 75
| 2.223011
| 0.026215
|
O00400,Q8N4V1,Q9BXP2,P21796,P45880,Q9C0H2,P20674,O43681,Q9Y487,O15439,Q93050,Q96ES6,P16615,Q13423,Q9HD20,P51790,Q9H2H9,Q7KZN9,P13073,P56385,Q9UDW1,P21281,P33527,P04920,Q9Y277,Q9UBX3,P05023,O95202,P98194,P00403,O75964,P24539,P51798,Q96QD8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
264,9,528,15,16,20,405,531,37,422,40,169,292,50,56,185,198,213,337,475,90,472,352,484,232,109,363,241,369,114,117,374,248,508
|
2036,264,422,531,2070,117,241,114,484,363,1457,856,818,1603,1828,1329,1036,1250,779,337,292,737,405,472,2320,15,707,374,969,921,352,748,1577,1927,16,2469,803,185,248,642,475,592,1405,369,1122,1020,50,730,2109,213,9,697,2231,2148,40,2270,169,508,1052,547,528,20,657,198,56,109,90,1112,1194,232,812,37,734,2460,840
|
-0.5379930941294808,1.2146655480675908,0.7749899149252996,0.5517730351345772,-0.5576770803133537,1.9838171226896273,1.3048961711518003,2.015974080477711,0.6424844207170954,0.9174606497851514,-0.23437919882369965,0.1682421911682641,0.20154814096271612,-0.30834940175024095,-0.4216838952161537,-0.16163385385214332,0.03238835570877815,-0.10785697374131768,0.2345983492140732,0.9869083646757261,1.122403168752099,0.28370179506564897,0.8182439888074761,0.672293189318447,-0.759434892091634,3.558604191488058,0.31612783470675104,0.8893532800594045,0.08383480077369695,0.11779590878562075,0.9453792994602913,0.2673963211845321,-0.2897399955466822,-0.46011623230476806,3.515789489534347,-0.9276215217752557,0.2181049920661174,1.5281289711930328,1.2793186260964378,0.39613357596639254,0.672293189318447,0.4590750194134483,-0.19785570229010588,0.9034306979462009,-0.019675434888960938,0.04960511328482398,2.831306853338417,0.2999454932185619,-0.5774483420396528,1.4056301198534875,3.724959724908723,0.33224923450336813,-0.6574202145206469,-0.5973075767254589,2.941956184280774,-0.6979483260765379,1.6235191019297979,0.5973722597638846,0.03238835570877815,0.536463418458696,0.5670274774060957,3.3618378249093492,0.38025187320722004,1.4795736761747307,2.690507421713021,2.0899995453915405,2.254119276071687,-0.0022514235063176217,-0.05473421435229654,1.3429641997032904,0.2181049920661174,2.975355597745126,0.2999454932185619,-0.9062528889503797,0.20154814096271612
| 2,702
|
Outer mitochondrial membrane protein complex
| 10
| 16
| 2.221858
| 0.026293
|
Q9NS69,Q15388,Q8N4H5,Q16891,Q13505,Q5XKP0,Q9BUR5,Q9NX63,O75431,Q6UXV4
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,295,39,493,42,371,276,341,252,413
|
252,1673,692,2539,42,295,493,371,413,544,39,276,0,872,341,690
|
1.2664695220524946,-0.3458054921469844,0.33224923450336813,-1.0579885203161268,2.9082562157141907,1.122403168752099,0.6275005747563835,0.9034306979462009,0.8038756116143992,0.536463418458696,2.9503340260738637,1.1753780817167876,4.339098672789817,0.1682421911682641,0.9869083646757261,0.3483101035432623
| 2,702
|
Ceramide metabolic process
| 7
| 16
| 2.221476
| 0.026319
|
P04062,P06280,O95470,P17900,Q13510,Q99805,P06865
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
134,104,107,82,55,251,253
|
495,1533,107,134,104,253,675,82,764,55,2614,1313,437,301,251,1165
|
0.6124633021363719,-0.2712088850102407,2.0899995453915405,1.90774847949041,2.1316806866838474,1.2664695220524946,0.3483101035432623,2.333654152549082,0.25102864836853117,2.6994624661868474,-1.307106361795847,-0.1436346549150024,0.7459035635880372,1.1090521543190752,1.2793186260964378,-0.03716952921365007
| 2,702
|
Monooxygenase activity
| 6
| 9
| 2.216422
| 0.026663
|
Q16850,Q14534,Q9BU89,Q15800,P09601,P30519
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
139,173,145,283,86,29
|
1638,86,29,575,173,283,139,398,145
|
-0.3270376997249967,2.2741564208043514,3.193293290882018,0.4901999107033141,1.5998828218041645,1.148975957368919,1.8413617509235753,0.8325631260445068,1.807747107129735
| 2,702
|
Subsets and Splits
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