term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hand polydactyly
| 12
| 26
| 2.20507
| 0.027449
|
Q9BXW9,Q10713,Q9UHX1,P21964,Q9Y263,Q14739,Q15067,O96028,O95202,Q9UBM7,P98175,O43924
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
384,453,38,356,203,235,141,123,241,153,476,27
|
27,241,123,2408,356,878,2076,476,453,1095,976,2301,235,2303,141,502,2330,2649,934,1388,384,2553,153,38,1194,203
|
3.216736188042297,1.3048961711518003,1.9622324023613926,-0.8427455410647996,0.9314434222343889,0.15149219850709802,-0.5576770803133537,0.672293189318447,0.7166140404526318,-0.0022514235063176217,0.08383480077369695,-0.7388457718106729,1.3303143323167068,-0.7388457718106729,1.8301884436274014,0.6124633021363719,-0.759434892091634,-1.570450064901612,0.11779590878562075,-0.17970735210207034,0.8752281069462309,-1.0800838670850532,1.7510836692846126,2.958693159055178,-0.05473421435229654,1.4550755191396691
| 2,702
|
Polyneuropathy
| 6
| 15
| 2.204763
| 0.027471
|
Q8N2K0,O60313,P07602,Q9NZJ7,Q9HC21,O95831
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
359,416,13,336,432,313
|
416,441,313,817,13,1398,1085,921,729,1156,1351,359,432,336,1667
|
0.7894576895397357,0.7312843575943586,1.055211388917935,0.20154814096271612,3.6358051961034,-0.19785570229010588,-0.0022514235063176217,0.11779590878562075,0.2999454932185619,-0.03716952921365007,-0.16163385385214332,0.9314434222343889,0.7604719773481496,1.0006594538170546,-0.3270376997249967
| 2,702
|
Antiporter activity
| 6
| 11
| 2.169231
| 0.030065
|
Q9UBX3,P41440,P12236,O95202,P51790,P51798
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
109,271,457,241,185,248
|
241,484,856,1329,779,457,271,185,248,1020,109
|
1.3048961711518003,0.6424844207170954,0.1682421911682641,-0.16163385385214332,0.2345983492140732,0.701892290350493,1.188515758083854,1.5281289711930328,1.2793186260964378,0.04960511328482398,2.0899995453915405
| 2,702
|
Ion transmembrane transporter activity
| 48
| 98
| 2.158739
| 0.03087
|
Q6P4A7,Q70HW3,O00400,Q8N4V1,Q9BXP2,P41440,P21796,P45880,Q9C0H2,P20674,O43681,Q8TB61,Q6NUK1,O43772,P11166,Q9Y487,O15439,Q93050,Q96ES6,P16615,Q9HC21,Q13423,Q9H2D1,Q9HD20,P51790,Q9H2H9,P12236,Q7KZN9,P13073,P56385,Q9UDW1,Q9BQT8,P21281,Q9Y619,Q8NEW0,P33527,P04920,Q9Y277,Q9UBX3,P05023,Q96QD8,O95202,P98194,P00403,P53985,O75964,P51798,P24539
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
259,5,264,9,528,271,15,16,20,405,531,152,419,162,539,37,422,40,169,292,432,50,51,56,185,198,457,213,337,475,90,93,472,351,96,352,484,232,109,363,508,241,369,114,244,117,248,374
|
2036,264,422,531,162,736,989,2070,117,241,966,114,484,363,1457,856,818,1603,1828,1329,1036,1250,539,779,457,337,292,737,405,472,2320,15,707,374,969,921,352,748,1577,1927,271,16,2469,803,185,248,244,642,475,592,1405,369,1122,1020,50,1021,1312,730,2109,419,1514,259,5,213,9,697,96,152,2231,2148,40,2270,169,809,508,1052,558,93,528,20,657,51,198,1133,432,56,109,90,1112,645,1194,232,812,37,734,351,2460,840
|
-0.5379930941294808,1.2146655480675908,0.7749899149252996,0.5517730351345772,1.6820076128894363,0.28370179506564897,0.0667537675442864,-0.5576770803133537,1.9838171226896273,1.3048961711518003,0.08383480077369695,2.015974080477711,0.6424844207170954,0.9174606497851514,-0.23437919882369965,0.1682421911682641,0.20154814096271612,-0.30834940175024095,-0.4216838952161537,-0.16163385385214332,0.03238835570877815,-0.10785697374131768,0.536463418458696,0.2345983492140732,0.701892290350493,0.9869083646757261,1.122403168752099,0.28370179506564897,0.8182439888074761,0.672293189318447,-0.759434892091634,3.558604191488058,0.31612783470675104,0.8893532800594045,0.08383480077369695,0.11779590878562075,0.9453792994602913,0.2673963211845321,-0.2897399955466822,-0.46011623230476806,1.188515758083854,3.515789489534347,-0.9276215217752557,0.2181049920661174,1.5281289711930328,1.2793186260964378,1.2921274336650987,0.39613357596639254,0.672293189318447,0.4590750194134483,-0.19785570229010588,0.9034306979462009,-0.019675434888960938,0.04960511328482398,2.831306853338417,0.04960511328482398,-0.1436346549150024,0.2999454932185619,-0.5774483420396528,0.7894576895397357,-0.2527554805154473,1.240649509692531,3.857928935292173,1.4056301198534875,3.724959724908723,0.33224923450336813,2.223868499779184,1.7738458790955642,-0.6574202145206469,-0.5973075767254589,2.941956184280774,-0.6979483260765379,1.6235191019297979,0.2181049920661174,0.5973722597638846,0.03238835570877815,0.5210982679469837,2.2440618128355347,0.5670274774060957,3.3618378249093492,0.38025187320722004,2.822658973915516,1.4795736761747307,-0.019675434888960938,0.7604719773481496,2.690507421713021,2.0899995453915405,2.254119276071687,-0.0022514235063176217,0.39613357596639254,-0.05473421435229654,1.3429641997032904,0.2181049920661174,2.975355597745126,0.2999454932185619,0.9592685631657338,-0.9062528889503797,0.20154814096271612
| 2,702
|
Vitamin transport
| 7
| 9
| 2.154148
| 0.031229
|
P33527,P04062,Q8WTV0,P41440,Q9HC21,Q9H2D1,P38435
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
352,134,202,271,432,51,183
|
134,539,352,183,271,202,51,432,812
|
1.90774847949041,0.536463418458696,0.9453792994602913,1.5521892607638046,1.188515758083854,1.4550755191396691,2.822658973915516,0.7604719773481496,0.2181049920661174
| 2,702
|
Oxidase
| 8
| 18
| 2.152348
| 0.03137
|
O43169,O15254,P14406,Q6ZRP7,Q15067,O15260,P20674,Q15800
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
2,261,7,424,141,207,405,283
|
261,207,2,497,1250,2642,2011,7,2072,405,1147,1610,860,141,283,424,1072,1163
|
1.2276781392572151,1.4304282132683406,3.979807696470662,0.6124633021363719,-0.10785697374131768,-1.497135064240729,-0.51839569402218,3.792063109742703,-0.5576770803133537,0.8182439888074761,-0.03716952921365007,-0.30834940175024095,0.1682421911682641,1.8301884436274014,1.148975957368919,0.7749899149252996,0.015103007549675692,-0.03716952921365007
| 2,702
|
Fad binding
| 6
| 9
| 2.145158
| 0.03194
|
Q8NB78,O15254,O00116,Q15067,Q15392,Q14534
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
195,261,290,141,142,173
|
290,261,313,2529,173,141,142,195,1385
|
1.122403168752099,1.2276781392572151,1.055211388917935,-1.0359996897457213,1.5998828218041645,1.8301884436274014,1.8301884436274014,1.4917673289663298,-0.17970735210207034
| 2,702
|
Glycerophospholipid biosynthetic process
| 7
| 30
| 2.142649
| 0.032141
|
Q9NPH0,Q8NF37,O95674,Q9BTU6,Q6P1A2,P35790,P48651
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,103,299,431,212,59,124
|
2240,702,1083,1674,299,59,1016,124,2427,1615,1069,453,1349,212,1157,103,2478,1625,1446,1005,1212,1520,1321,431,2257,4,1109,718,873,628
|
-0.6776384784971092,0.31612783470675104,-0.0022514235063176217,-0.3458054921469844,1.1090521543190752,2.6180971611507324,0.04960511328482398,1.9622324023613926,-0.8638157361636718,-0.30834940175024095,0.015103007549675692,0.7166140404526318,-0.16163385385214332,1.4056301198534875,-0.03716952921365007,2.1420319569801767,-0.9276215217752557,-0.30834940175024095,-0.21607946299314143,0.0667537675442864,-0.07237000350541305,-0.2527554805154473,-0.1436346549150024,0.7604719773481496,-0.6776384784971092,3.9417705569579184,-0.0022514235063176217,0.31612783470675104,0.1682421911682641,0.42772059381643684
| 2,702
|
Selective autophagy
| 12
| 28
| 2.139638
| 0.032384
|
Q9NS69,Q15388,Q8N4H5,P50542,P04350,P21796,P07900,P08670,P68371,Q13885,Q8IWA4,P54619
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,295,39,490,552,15,523,208,311,446,544,320
|
722,723,1673,692,552,523,208,1331,2219,15,490,320,1877,997,1685,311,2531,446,1345,295,544,39,808,2636,961,606,0,1221
|
0.2999454932185619,0.2999454932185619,-0.3458054921469844,0.33224923450336813,0.5210982679469837,0.5670274774060957,1.4304282132683406,-0.16163385385214332,-0.6574202145206469,3.558604191488058,0.6275005747563835,1.0416407333608675,-0.44085843678176667,0.0667537675442864,-0.3458054921469844,1.06873759915191,-1.0359996897457213,0.7312843575943586,-0.16163385385214332,1.122403168752099,0.536463418458696,2.9503340260738637,0.2181049920661174,-1.4488924573325177,0.10084869034597146,0.4434266881560912,4.339098672789817,-0.07237000350541305
| 2,702
|
Proteasome, subunit alpha/beta [IPR001353]
| 6
| 14
| 2.139267
| 0.032414
|
P49721,P20618,P28072,P28074,P60900,P28070
|
Sequence
|
InterPro Family
|
interpro_family
|
35,293,177,308,309,125
|
1705,293,1575,747,799,1536,2298,125,177,308,898,35,309,330
|
-0.3646533883592373,1.122403168752099,-0.2897399955466822,0.2673963211845321,0.2181049920661174,-0.2712088850102407,-0.7388457718106729,1.9513955835040788,1.5761067056736178,1.0822196248016487,0.13467692383293534,3.0166894806603843,1.0822196248016487,1.0143650321652233
| 2,702
|
Proteasome core complex
| 6
| 14
| 2.139267
| 0.032414
|
P49721,P20618,P28072,P28074,P60900,P28070
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
35,293,177,308,309,125
|
1705,293,1575,747,799,1536,2298,125,177,308,898,35,309,330
|
-0.3646533883592373,1.122403168752099,-0.2897399955466822,0.2673963211845321,0.2181049920661174,-0.2712088850102407,-0.7388457718106729,1.9513955835040788,1.5761067056736178,1.0822196248016487,0.13467692383293534,3.0166894806603843,1.0822196248016487,1.0143650321652233
| 2,702
|
Abnormal tissue metabolite concentration
| 8
| 12
| 2.138986
| 0.032437
|
P06280,P50542,P07602,Q9NZJ7,P17900,P40855,P06865,O75381
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
104,490,13,336,82,314,253,319
|
531,319,104,253,13,675,82,314,490,1682,336,1594
|
0.5517730351345772,1.0416407333608675,2.1316806866838474,1.2664695220524946,3.6358051961034,0.3483101035432623,2.333654152549082,1.055211388917935,0.6275005747563835,-0.3458054921469844,1.0006594538170546,-0.2897399955466822
| 2,702
|
Ventricular hypertrophy
| 9
| 30
| 2.138317
| 0.032491
|
O43772,O75844,P10253,O95630,Q9BV10,P06280,P00403,O75431,P23786
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
162,67,196,355,200,104,114,252,63
|
735,162,252,67,497,355,114,967,104,196,779,599,63,2396,1173,1577,2300,1463,2020,2376,862,1344,1584,711,419,2329,1481,200,2062,1529
|
0.28370179506564897,1.6820076128894363,1.2664695220524946,2.525606359287873,0.6124633021363719,0.9314434222343889,2.015974080477711,0.08383480077369695,2.1316806866838474,1.4795736761747307,0.2345983492140732,0.4434266881560912,2.5721316468788222,-0.8217731668728108,-0.05473421435229654,-0.2897399955466822,-0.7388457718106729,-0.23437919882369965,-0.51839569402218,-0.8008978009850447,0.1682421911682641,-0.16163385385214332,-0.2897399955466822,0.31612783470675104,0.7894576895397357,-0.759434892091634,-0.23437919882369965,1.4673431398478316,-0.5379930941294808,-0.2527554805154473
| 2,702
|
Nucleotide transmembrane transporter activity
| 8
| 12
| 2.138121
| 0.032507
|
Q6NUK1,O15439,O00400,P41440,P12236,Q9HC21,Q9H2D1,Q8TB61
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
419,422,264,271,457,432,51,152
|
264,422,736,856,779,457,271,419,152,558,51,432
|
1.2146655480675908,0.7749899149252996,0.28370179506564897,0.1682421911682641,0.2345983492140732,0.701892290350493,1.188515758083854,0.7894576895397357,1.7738458790955642,0.5210982679469837,2.822658973915516,0.7604719773481496
| 2,702
|
Organophosphate ester transmembrane transporter activity
| 8
| 12
| 2.138121
| 0.032507
|
Q6NUK1,O15439,O00400,P41440,P12236,Q9HC21,Q9H2D1,Q8TB61
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
419,422,264,271,457,432,51,152
|
264,422,736,856,779,457,271,419,152,558,51,432
|
1.2146655480675908,0.7749899149252996,0.28370179506564897,0.1682421911682641,0.2345983492140732,0.701892290350493,1.188515758083854,0.7894576895397357,1.7738458790955642,0.5210982679469837,2.822658973915516,0.7604719773481496
| 2,702
|
Adrenal insufficiency
| 7
| 25
| 2.137041
| 0.032595
|
P16435,O95470,Q9NSE4,Q13423,P33991,P40855,O75381
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
258,107,172,50,23,314,319
|
735,319,704,107,2042,258,365,23,1499,525,314,490,1682,1759,1549,50,1621,1622,1904,1053,2234,1423,172,1822,597
|
0.28370179506564897,1.0416407333608675,0.31612783470675104,2.0899995453915405,-0.5379930941294808,1.240649509692531,0.9174606497851514,3.2631795329313182,-0.2527554805154473,0.5670274774060957,1.055211388917935,0.6275005747563835,-0.3458054921469844,-0.3835820044684915,-0.2712088850102407,2.831306853338417,-0.30834940175024095,-0.30834940175024095,-0.44085843678176667,0.03238835570877815,-0.6574202145206469,-0.19785570229010588,1.6117183489592206,-0.4025919634436768,0.4590750194134483
| 2,702
|
Alcohol biosynthetic process
| 13
| 32
| 2.12748
| 0.03338
|
O75477,P16435,P04062,Q16850,Q14739,Q15392,P48449,P37268,O94905,Q6P1A2,Q15800,Q13510,Q9UBM7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
192,258,134,139,235,142,242,147,180,212,283,55,153
|
2660,495,1533,192,1427,180,411,2529,134,1459,694,258,1956,147,2321,242,1876,575,2225,55,2520,235,2228,142,1963,283,329,139,212,2636,2364,153
|
-1.695259350723434,0.6124633021363719,-0.2712088850102407,1.4917673289663298,-0.21607946299314143,1.5641657435116996,0.8038756116143992,-1.0359996897457213,1.90774847949041,-0.23437919882369965,0.33224923450336813,1.240649509692531,-0.4794579332236154,1.7964787566429434,-0.759434892091634,1.3048961711518003,-0.44085843678176667,0.4901999107033141,-0.6574202145206469,2.6994624661868474,-1.0141164567184937,1.3303143323167068,-0.6574202145206469,1.8301884436274014,-0.4794579332236154,1.148975957368919,1.0143650321652233,1.8413617509235753,1.4056301198534875,-1.4488924573325177,-0.7801186405050577,1.7510836692846126
| 2,702
|
Deep palmar crease
| 6
| 12
| 2.124636
| 0.033617
|
Q6NUK1,P61978,Q9Y487,P98175,O75431,P21281
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
419,479,37,476,252,472
|
735,252,472,1148,532,479,476,1042,1258,419,1269,37
|
0.28370179506564897,1.2664695220524946,0.672293189318447,-0.03716952921365007,0.5517730351345772,0.6574151799611627,0.672293189318447,0.03238835570877815,-0.10785697374131768,0.7894576895397357,-0.10785697374131768,2.975355597745126
| 2,702
|
Mitochondrial calcium ion transport
| 7
| 15
| 2.113265
| 0.034578
|
Q9BPX6,Q9Y277,P21796,P45880,O95202,Q8WWC4,Q99623
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
257,232,15,16,241,438,415
|
1712,241,15,1679,16,453,697,438,1658,1131,415,257,559,232,660
|
-0.3646533883592373,1.3048961711518003,3.558604191488058,-0.3458054921469844,3.515789489534347,0.7166140404526318,0.33224923450336813,0.7459035635880372,-0.3270376997249967,-0.019675434888960938,0.8038756116143992,1.2535798932893194,0.5210982679469837,1.3429641997032904,0.38025187320722004
| 2,702
|
Endoplasmic reticulum organization
| 15
| 38
| 2.099141
| 0.035804
|
Q15629,A0FGR8,Q12907,Q9NQC3,Q96A33,P46379,Q9P2W9,Q8N4V1,Q8NHH9,P50542,Q15363,Q6P1A2,O43681,O95197,P57088
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,317,541,131,250,167,105,9,463,490,111,212,531,25,382
|
317,744,639,1634,1224,531,1367,943,25,1642,167,879,490,382,1405,540,541,739,1438,111,64,979,955,212,2695,9,1289,1443,463,250,1107,1293,889,131,1165,1029,1524,105
|
1.0416407333608675,0.2673963211845321,0.39613357596639254,-0.3270376997249967,-0.09007741527544748,0.5517730351345772,-0.17970735210207034,0.10084869034597146,3.240031045214478,-0.3270376997249967,1.658714539425245,0.15149219850709802,0.6275005747563835,0.8752281069462309,-0.19785570229010588,0.536463418458696,0.536463418458696,0.28370179506564897,-0.21607946299314143,2.079509582008797,2.5628717612311127,0.08383480077369695,0.10084869034597146,1.4056301198534875,-5.352839700329882,3.724959724908723,-0.1257092085342695,-0.21607946299314143,0.701892290350493,1.2793186260964378,-0.0022514235063176217,-0.1257092085342695,0.15149219850709802,1.9187055275737044,-0.03716952921365007,0.04960511328482398,-0.2527554805154473,2.1316806866838474
| 2,702
|
Passive transmembrane transporter activity
| 6
| 31
| 2.093421
| 0.036312
|
Q9Y277,P21796,P45880,Q9C0H2,O75964,P51790
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
232,15,16,20,117,185
|
2036,2070,117,692,818,1603,1828,15,374,969,748,1927,16,2469,803,185,248,642,475,1405,730,697,2231,2148,2270,1052,547,20,1194,232,2460
|
-0.5379930941294808,-0.5576770803133537,1.9838171226896273,0.33224923450336813,0.20154814096271612,-0.30834940175024095,-0.4216838952161537,3.558604191488058,0.8893532800594045,0.08383480077369695,0.2673963211845321,-0.46011623230476806,3.515789489534347,-0.9276215217752557,0.2181049920661174,1.5281289711930328,1.2793186260964378,0.39613357596639254,0.672293189318447,-0.19785570229010588,0.2999454932185619,0.33224923450336813,-0.6574202145206469,-0.5973075767254589,-0.6979483260765379,0.03238835570877815,0.536463418458696,3.3618378249093492,-0.05473421435229654,1.3429641997032904,-0.9062528889503797
| 2,702
|
Amide transport
| 10
| 34
| 2.09024
| 0.036596
|
P33527,O15439,Q16822,O00400,P41440,P07602,Q9NZJ7,Q9H2D1,P08183,P53985
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
352,422,329,264,271,13,336,51,84,244
|
2003,1532,1704,264,422,1599,966,651,894,13,84,1303,2100,582,1608,352,1463,271,244,1340,1255,975,1154,1343,429,329,785,697,2636,51,336,1524,2553,812
|
-0.51839569402218,-0.2712088850102407,-0.3646533883592373,1.2146655480675908,0.7749899149252996,-0.30834940175024095,0.08383480077369695,0.38025187320722004,0.13467692383293534,3.6358051961034,2.3040194739784066,-0.1436346549150024,-0.5774483420396528,0.4746659679952571,-0.30834940175024095,0.9453792994602913,-0.23437919882369965,1.188515758083854,1.2921274336650987,-0.16163385385214332,-0.10785697374131768,0.08383480077369695,-0.03716952921365007,-0.16163385385214332,0.7604719773481496,1.0143650321652233,0.2345983492140732,0.33224923450336813,-1.4488924573325177,2.822658973915516,1.0006594538170546,-0.2527554805154473,-1.0800838670850532,0.2181049920661174
| 2,702
|
Vitamin transmembrane transporter activity
| 6
| 8
| 2.084697
| 0.037097
|
P33527,P04062,P41440,Q9HC21,Q9H2D1,P38435
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
352,134,271,432,51,183
|
134,539,352,183,271,51,432,812
|
1.90774847949041,0.536463418458696,0.9453792994602913,1.5521892607638046,1.188515758083854,2.822658973915516,0.7604719773481496,0.2181049920661174
| 2,702
|
Lipid transporter activity
| 10
| 19
| 2.083462
| 0.037209
|
P33527,P11166,O15118,O15439,P22059,P61916,P17900,P08183,Q9H4L5,P30536
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
352,539,69,422,582,300,82,84,310,151
|
69,422,84,539,82,582,1086,151,352,1149,300,2427,730,1514,604,834,1735,2332,310
|
2.497417369060405,0.7749899149252996,2.3040194739784066,0.536463418458696,2.333654152549082,0.4746659679952571,-0.0022514235063176217,1.7738458790955642,0.9453792994602913,-0.03716952921365007,1.1090521543190752,-0.8638157361636718,0.2999454932185619,-0.2527554805154473,0.4434266881560912,0.20154814096271612,-0.3646533883592373,-0.759434892091634,1.0822196248016487
| 2,702
|
Sphingolipid metabolism in senescence
| 6
| 9
| 2.080802
| 0.037452
|
P16278,P04062,Q96G23,O15269,Q13510,Q06136
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
36,134,301,495,55,189
|
495,134,991,36,1796,532,189,55,301
|
0.6124633021363719,1.90774847949041,0.0667537675442864,3.000210798187082,-0.4025919634436768,0.5517730351345772,1.5160447795129783,2.6994624661868474,1.1090521543190752
| 2,702
|
Metal ion transmembrane transporter activity
| 15
| 24
| 2.077758
| 0.037732
|
P49768,P20020,Q9H2H9,Q8N4V1,P16615,Q9BXP2,Q9H0U3,P23634,P05023,O95202,P98194,Q8NE86,Q9HD20,Q96QD8,Q9Y289
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
803,737,198,9,292,528,657,707,363,241,369,697,56,508,812
|
241,363,1457,1603,1828,1329,292,737,707,803,1405,369,9,697,2148,2270,508,528,657,198,56,1194,812,840
|
1.3048961711518003,0.9174606497851514,-0.23437919882369965,-0.30834940175024095,-0.4216838952161537,-0.16163385385214332,1.122403168752099,0.28370179506564897,0.31612783470675104,0.2181049920661174,-0.19785570229010588,0.9034306979462009,3.724959724908723,0.33224923450336813,-0.5973075767254589,-0.6979483260765379,0.5973722597638846,0.5670274774060957,0.38025187320722004,1.4795736761747307,2.690507421713021,-0.05473421435229654,0.2181049920661174,0.20154814096271612
| 2,702
|
Abnormal metatarsal morphology
| 8
| 20
| 2.077641
| 0.037742
|
P16435,Q08J23,O96028,Q15392,O95202,O43505,Q9UBM7,P08236
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
258,130,123,142,241,149,153,343
|
149,2390,241,123,343,845,258,2408,1796,365,490,750,1069,130,2301,1764,142,2328,1212,153
|
1.7851784018367542,-0.8217731668728108,1.3048961711518003,1.9622324023613926,0.97311149261789,0.18492735557866916,1.240649509692531,-0.8427455410647996,-0.4025919634436768,0.9174606497851514,0.6275005747563835,0.2673963211845321,0.015103007549675692,1.9187055275737044,-0.7388457718106729,-0.3835820044684915,1.8301884436274014,-0.759434892091634,-0.07237000350541305,1.7510836692846126
| 2,702
|
Endocytic vesicle membrane
| 9
| 33
| 2.069219
| 0.038526
|
P02786,Q9Y487,Q14108,Q93050,Q8WTV0,P10321,Q5KU26,P11717,P11279
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
322,37,8,40,202,326,106,373,221
|
2504,550,2158,1643,322,2099,326,221,373,1647,662,2346,615,1336,1065,1039,1929,592,2139,2053,1615,975,1343,1890,8,928,429,106,202,40,1317,1520,37
|
-0.9923379139698841,0.5210982679469837,-0.6172554898593413,-0.3270376997249967,1.028025369515471,-0.5774483420396528,1.0143650321652233,1.3806795740768194,0.8893532800594045,-0.3270376997249967,0.36431084877418707,-0.7801186405050577,0.42772059381643684,-0.16163385385214332,0.015103007549675692,0.03238835570877815,-0.46011623230476806,0.4590750194134483,-0.5973075767254589,-0.5379930941294808,-0.30834940175024095,0.08383480077369695,-0.16163385385214332,-0.44085843678176667,3.724959724908723,0.11779590878562075,0.7604719773481496,2.100461504027298,1.4550755191396691,2.941956184280774,-0.1436346549150024,-0.2527554805154473,2.975355597745126
| 2,702
|
Nucleobase containing compound transmembrane transporter activity
| 8
| 14
| 2.06628
| 0.038802
|
Q6NUK1,O15439,O00400,P41440,P12236,Q9HC21,Q9H2D1,Q8TB61
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
419,422,264,271,457,432,51,152
|
1298,264,422,736,856,779,457,271,641,419,152,558,51,432
|
-0.1436346549150024,1.2146655480675908,0.7749899149252996,0.28370179506564897,0.1682421911682641,0.2345983492140732,0.701892290350493,1.188515758083854,0.39613357596639254,0.7894576895397357,1.7738458790955642,0.5210982679469837,2.822658973915516,0.7604719773481496
| 2,702
|
Aplasia hypoplasia of toe
| 7
| 31
| 2.064405
| 0.038979
|
Q9UHX1,Q03164,O95202,Q13510,Q9UBM7,O96028,P00813
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
38,48,241,55,153,123,155
|
2589,650,241,1397,123,155,967,845,337,2408,2073,897,48,1069,2569,2301,55,1311,2055,955,1258,1158,2058,1159,1357,1105,873,2553,153,2311,38
|
-1.192191318168698,0.38025187320722004,1.3048961711518003,-0.19785570229010588,1.9622324023613926,1.7281907938755132,0.08383480077369695,0.18492735557866916,0.9869083646757261,-0.8427455410647996,-0.5576770803133537,0.13467692383293534,2.839934928116633,0.015103007549675692,-1.124597841923488,-0.7388457718106729,2.6994624661868474,-0.1436346549150024,-0.5379930941294808,0.10084869034597146,-0.10785697374131768,-0.03716952921365007,-0.5379930941294808,-0.03716952921365007,-0.16163385385214332,-0.0022514235063176217,0.1682421911682641,-1.0800838670850532,1.7510836692846126,-0.7388457718106729,2.958693159055178
| 2,702
|
Abnormal enchondral ossification
| 10
| 23
| 2.064308
| 0.038989
|
O00116,Q14739,O96028,O95202,Q96HY6,P08236,P38435,Q9UBM7,P40855,O75381
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,235,123,241,339,343,183,153,314,319
|
290,2390,319,241,123,343,845,2408,2074,183,314,490,2351,1069,2301,235,1764,1963,2330,339,153,628,351
|
1.122403168752099,-0.8217731668728108,1.0416407333608675,1.3048961711518003,1.9622324023613926,0.97311149261789,0.18492735557866916,-0.8427455410647996,-0.5576770803133537,1.5521892607638046,1.055211388917935,0.6275005747563835,-0.7801186405050577,0.015103007549675692,-0.7388457718106729,1.3303143323167068,-0.3835820044684915,-0.4794579332236154,-0.759434892091634,0.9869083646757261,1.7510836692846126,0.42772059381643684,0.9592685631657338
| 2,702
|
Respirasome
| 12
| 40
| 2.060795
| 0.039323
|
Q9P0J0,Q9Y6M9,P14406,Q6DKK2,Q86Y39,Q13423,P00403,O14949,Q7KZN9,O96000,Q9UDW1,O43676
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
132,133,7,204,335,50,114,116,213,119,90,30
|
2638,1247,116,30,1366,2389,1272,1369,1785,471,724,2121,2009,119,114,1036,2160,1250,337,7,2072,2537,405,599,663,2517,2396,921,2627,1613,50,1844,1381,204,213,335,132,90,1594,133
|
-1.472951143850942,-0.10785697374131768,2.00528425298711,3.08995471113118,-0.17970735210207034,-0.8217731668728108,-0.1257092085342695,-0.17970735210207034,-0.4025919634436768,0.672293189318447,0.2999454932185619,-0.5973075767254589,-0.51839569402218,1.9730395335085762,2.015974080477711,0.03238835570877815,-0.6172554898593413,-0.10785697374131768,0.9869083646757261,3.792063109742703,-0.5576770803133537,-1.0579885203161268,0.8182439888074761,0.4434266881560912,0.36431084877418707,-1.0141164567184937,-0.8217731668728108,0.11779590878562075,-1.3774562790616307,-0.30834940175024095,2.831306853338417,-0.4216838952161537,-0.17970735210207034,1.442770611622072,1.4056301198534875,1.0006594538170546,1.9187055275737044,2.254119276071687,-0.2897399955466822,1.9187055275737044
| 2,702
|
Respiratory chain
| 7
| 29
| 2.039812
| 0.041369
|
Q9P0J0,Q9Y6M9,P00403,O14949,O96000,Q9UDW1,O43676
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
132,133,114,116,119,90,30
|
2638,1247,116,30,1366,2389,1272,1369,1785,471,724,2121,2009,119,114,1036,2537,663,2517,921,2627,1613,1844,1381,204,335,132,90,133
|
-1.472951143850942,-0.10785697374131768,2.00528425298711,3.08995471113118,-0.17970735210207034,-0.8217731668728108,-0.1257092085342695,-0.17970735210207034,-0.4025919634436768,0.672293189318447,0.2999454932185619,-0.5973075767254589,-0.51839569402218,1.9730395335085762,2.015974080477711,0.03238835570877815,-1.0579885203161268,0.36431084877418707,-1.0141164567184937,0.11779590878562075,-1.3774562790616307,-0.30834940175024095,-0.4216838952161537,-0.17970735210207034,1.442770611622072,1.0006594538170546,1.9187055275737044,2.254119276071687,1.9187055275737044
| 2,702
|
Lipid transport
| 7
| 20
| 2.027192
| 0.042643
|
A0FGR8,Q99720,O15118,Q9BQE5,P61916,Q9BUR5,Q9H4L5
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
317,3,69,12,300,276,310
|
317,69,2391,582,1794,300,1932,730,1514,604,2667,834,3,12,1107,276,1735,2332,346,310
|
1.0416407333608675,2.497417369060405,-0.8217731668728108,0.4746659679952571,-0.4025919634436768,1.1090521543190752,-0.46011623230476806,0.2999454932185619,-0.2527554805154473,0.4434266881560912,-1.7461289120306243,0.20154814096271612,3.979807696470662,3.642742245523358,-0.0022514235063176217,1.1753780817167876,-0.3646533883592373,-0.759434892091634,0.97311149261789,1.0822196248016487
| 2,702
|
Protein insertion into membrane
| 7
| 28
| 2.022377
| 0.043137
|
Q9NS69,Q15629,Q9P0J0,P46379,Q8N4V1,O14737,Q15070
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,64,132,167,9,233,110
|
233,1224,531,1367,1673,523,1678,2103,167,1405,1438,110,64,1313,979,2695,9,1289,438,250,889,0,1029,132,1594,690,342,612
|
1.3303143323167068,-0.09007741527544748,0.5517730351345772,-0.17970735210207034,-0.3458054921469844,0.5670274774060957,-0.3458054921469844,-0.5774483420396528,1.658714539425245,-0.19785570229010588,-0.21607946299314143,2.079509582008797,2.5628717612311127,-0.1436346549150024,0.08383480077369695,-5.352839700329882,3.724959724908723,-0.1257092085342695,0.7459035635880372,1.2793186260964378,0.15149219850709802,4.339098672789817,0.04960511328482398,1.9187055275737044,-0.2897399955466822,0.3483101035432623,0.9869083646757261,0.4434266881560912
| 2,702
|
Abnormality of adrenal physiology
| 7
| 30
| 2.018942
| 0.043493
|
P16435,O95470,Q9NSE4,Q13423,P33991,P40855,O75381
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
258,107,172,50,23,314,319
|
735,319,704,107,2042,917,845,258,2043,365,23,1499,525,314,490,1682,1759,1615,1549,50,1234,1621,1622,1904,1053,2234,1423,172,1822,597
|
0.28370179506564897,1.0416407333608675,0.31612783470675104,2.0899995453915405,-0.5379930941294808,0.11779590878562075,0.18492735557866916,1.240649509692531,-0.5379930941294808,0.9174606497851514,3.2631795329313182,-0.2527554805154473,0.5670274774060957,1.055211388917935,0.6275005747563835,-0.3458054921469844,-0.3835820044684915,-0.30834940175024095,-0.2712088850102407,2.831306853338417,-0.09007741527544748,-0.30834940175024095,-0.30834940175024095,-0.44085843678176667,0.03238835570877815,-0.6574202145206469,-0.19785570229010588,1.6117183489592206,-0.4025919634436768,0.4590750194134483
| 2,702
|
Supranuclear gaze palsy
| 6
| 15
| 2.018159
| 0.043575
|
Q99720,P35637,O15118,P04062,P61916,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
3,328,69,134,300,13
|
2432,841,69,134,13,2124,328,1877,300,1763,643,3,336,2418,758
|
-0.8849845746322226,0.18492735557866916,2.497417369060405,1.90774847949041,3.6358051961034,-0.5973075767254589,1.0143650321652233,-0.44085843678176667,1.1090521543190752,-0.3835820044684915,0.39613357596639254,3.979807696470662,1.0006594538170546,-0.8427455410647996,0.2673963211845321
| 2,702
|
Retrograde transport endosome to golgi
| 8
| 31
| 2.013758
| 0.044035
|
Q13190,Q9Y5X3,Q9BVK6,O15260,Q8NBN3,Q8N1B4,O75503,O95249
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
323,238,175,207,87,435,247,279
|
207,988,915,794,456,2097,247,279,896,879,1336,1065,1177,2053,323,884,643,1099,1691,865,435,87,1128,1444,1211,175,1448,2554,608,742,238
|
1.4304282132683406,0.0667537675442864,0.11779590878562075,0.2181049920661174,0.701892290350493,-0.5774483420396528,1.2793186260964378,1.148975957368919,0.13467692383293534,0.15149219850709802,-0.16163385385214332,0.015103007549675692,-0.05473421435229654,-0.5379930941294808,1.028025369515471,0.15149219850709802,0.39613357596639254,-0.0022514235063176217,-0.3458054921469844,0.1682421911682641,0.7459035635880372,2.2741564208043514,-0.019675434888960938,-0.21607946299314143,-0.07237000350541305,1.5998828218041645,-0.21607946299314143,-1.0800838670850532,0.4434266881560912,0.28370179506564897,1.3303143323167068
| 2,702
|
Bilateral sensorineural hearing impairment
| 7
| 19
| 2.01129
| 0.044295
|
P35637,Q9NSE4,P07602,Q9NZJ7,Q15067,P00403,P38159
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
328,172,13,336,141,114,375
|
531,114,13,877,1274,1923,328,375,2164,1877,729,1763,407,141,681,620,172,336,1860
|
0.5517730351345772,2.015974080477711,3.6358051961034,0.15149219850709802,-0.1257092085342695,-0.46011623230476806,1.0143650321652233,0.8893532800594045,-0.6172554898593413,-0.44085843678176667,0.2999454932185619,-0.3835820044684915,0.8182439888074761,1.8301884436274014,0.3483101035432623,0.42772059381643684,1.6117183489592206,1.0006594538170546,-0.4216838952161537
| 2,702
|
Dolichocephaly
| 10
| 25
| 2.006232
| 0.044832
|
Q9BXW9,O95721,P61978,P21281,P31749,O96028,Q03164,O95202,P40855,O75381
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
384,441,479,472,365,123,48,241,314,319
|
319,241,2042,441,123,2464,472,920,365,314,1016,1835,995,490,1682,479,729,48,1069,2301,2474,1099,1105,384,2117
|
1.0416407333608675,1.3048961711518003,-0.5379930941294808,0.7312843575943586,1.9622324023613926,-0.9276215217752557,0.672293189318447,0.11779590878562075,0.9174606497851514,1.055211388917935,0.04960511328482398,-0.4216838952161537,0.0667537675442864,0.6275005747563835,-0.3458054921469844,0.6574151799611627,0.2999454932185619,2.839934928116633,0.015103007549675692,-0.7388457718106729,-0.9276215217752557,-0.0022514235063176217,-0.0022514235063176217,0.8752281069462309,-0.5774483420396528
| 2,702
|
Carbohydrate derivative catabolic process
| 11
| 31
| 2.005794
| 0.044878
|
P16278,P04062,P06280,Q9H773,P54802,O60502,P17900,P08236,P15586,P00813,P06865
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
36,134,104,75,77,78,82,343,280,155,253
|
1246,78,2483,1867,155,134,817,104,253,675,343,280,36,82,2516,2130,2691,1756,1253,77,765,515,1899,1939,1519,466,2630,75,360,2641,1113
|
-0.10785697374131768,2.4019310104088376,-0.9490913261043828,-0.44085843678176667,1.7281907938755132,1.90774847949041,0.20154814096271612,2.1316806866838474,1.2664695220524946,0.3483101035432623,0.97311149261789,1.148975957368919,3.000210798187082,2.333654152549082,-1.0141164567184937,-0.5973075767254589,-3.198448496175523,-0.3835820044684915,-0.10785697374131768,2.4115869799105853,0.25102864836853117,0.5822271013569861,-0.44085843678176667,-0.46011623230476806,-0.2527554805154473,0.701892290350493,-1.4011461617990972,2.4308266158331455,0.9314434222343889,-1.472951143850942,-0.0022514235063176217
| 2,702
|
Nephrotic syndrome
| 6
| 18
| 2.003956
| 0.045075
|
O95721,Q14108,P06280,O95470,Q8N1F7,P00813
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
441,8,104,107,436,155
|
107,441,155,104,1233,527,1338,750,862,1070,8,1622,436,1383,849,984,1388,2553
|
2.0899995453915405,0.7312843575943586,1.7281907938755132,2.1316806866838474,-0.09007741527544748,0.5670274774060957,-0.16163385385214332,0.2673963211845321,0.1682421911682641,0.015103007549675692,3.724959724908723,-0.30834940175024095,0.7459035635880372,-0.17970735210207034,0.18492735557866916,0.08383480077369695,-0.17970735210207034,-1.0800838670850532
| 2,702
|
Abnormal pulmonary interstitial morphology
| 7
| 29
| 2.003655
| 0.045107
|
P04062,Q14108,Q9NSD9,Q8IZA0,P09601,Q13510,Q13432
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
134,8,303,209,86,55,62
|
1031,2482,2275,2315,134,86,2465,1716,2449,1335,1064,2400,527,1338,2022,952,62,55,8,1346,1895,1813,1847,209,2253,303,1217,331,672
|
0.03238835570877815,-0.9490913261043828,-0.7183505049899396,-0.759434892091634,1.90774847949041,2.2741564208043514,-0.9276215217752557,-0.3646533883592373,-0.9062528889503797,-0.16163385385214332,0.015103007549675692,-0.8217731668728108,0.5670274774060957,-0.16163385385214332,-0.51839569402218,0.10084869034597146,2.581369142815388,2.6994624661868474,3.724959724908723,-0.16163385385214332,-0.44085843678176667,-0.4025919634436768,-0.4216838952161537,1.4304282132683406,-0.6776384784971092,1.1090521543190752,-0.07237000350541305,1.0143650321652233,0.36431084877418707
| 2,702
|
Cellular response to oxygen levels
| 14
| 31
| 2.001332
| 0.045357
|
Q15118,Q9Y487,Q99808,P55786,P31749,Q9NQ88,Q15904,P09601,P42345,Q96A26,O95831,P07237,Q9Y4P3,Q99623
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
577,37,558,74,365,306,501,86,532,88,313,381,350,415
|
1272,313,2448,967,917,2613,381,86,365,1927,532,2321,1064,74,592,577,1156,501,1845,1479,88,1385,415,558,306,962,2481,2033,37,2335,350
|
-0.1257092085342695,1.055211388917935,-0.9062528889503797,0.08383480077369695,0.11779590878562075,-1.307106361795847,0.8752281069462309,2.2741564208043514,0.9174606497851514,-0.46011623230476806,0.5517730351345772,-0.759434892091634,0.015103007549675692,2.4308266158331455,0.4590750194134483,0.4901999107033141,-0.03716952921365007,0.6124633021363719,-0.4216838952161537,-0.23437919882369965,2.2641507720080853,-0.17970735210207034,0.8038756116143992,0.5210982679469837,1.0956577244042058,0.10084869034597146,-0.9276215217752557,-0.51839569402218,2.975355597745126,-0.759434892091634,0.9592685631657338
| 2,702
|
Flavin adenine dinucleotide binding
| 9
| 25
| 1.997612
| 0.045759
|
P16435,Q8NB78,O15254,O00116,Q15067,Q15392,Q14534,A1L0T0,O95831
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
258,195,261,290,141,142,173,216,313
|
216,290,261,1169,313,2529,1675,875,2642,2011,2195,258,1147,2396,860,173,141,142,333,2606,1072,195,1902,1385,1163
|
1.393174008596331,1.122403168752099,1.2276781392572151,-0.05473421435229654,1.055211388917935,-1.0359996897457213,-0.3458054921469844,0.15149219850709802,-1.497135064240729,-0.51839569402218,-0.6372927951239112,1.240649509692531,-0.03716952921365007,-0.8217731668728108,0.1682421911682641,1.5998828218041645,1.8301884436274014,1.8301884436274014,1.0006594538170546,-1.2607953742196762,0.015103007549675692,1.4917673289663298,-0.44085843678176667,-0.17970735210207034,-0.03716952921365007
| 2,702
|
Glycosidase
| 7
| 18
| 1.997125
| 0.045812
|
P10253,P16278,P04062,P06280,P54802,O60502,P06865
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
196,36,134,104,77,78,253
|
2685,703,78,134,817,104,253,675,343,196,36,1173,77,765,1584,1892,1808,466
|
-2.345009462881344,0.31612783470675104,2.4019310104088376,1.90774847949041,0.20154814096271612,2.1316806866838474,1.2664695220524946,0.3483101035432623,0.97311149261789,1.4795736761747307,3.000210798187082,-0.05473421435229654,2.4115869799105853,0.25102864836853117,-0.2897399955466822,-0.44085843678176667,-0.4025919634436768,0.701892290350493
| 2,702
|
Copi dependent golgi to er retrograde traffic
| 17
| 45
| 1.994338
| 0.046115
|
Q86Y91,O14579,Q9P2W9,P24390,P04350,Q9BVK6,O75396,Q9H0H5,O15260,Q15363,P49755,Q9Y3B3,P68371,Q9BVA1,Q13885,Q8N6T3,P52732
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
66,260,105,10,552,175,550,239,207,111,614,150,311,606,446,603,444
|
1916,260,207,2005,550,1395,1060,552,1605,10,1231,1199,1755,995,614,444,2047,2400,1614,1683,1340,311,1310,1094,828,739,446,1764,111,633,66,603,1128,2174,1262,961,606,175,838,239,105,1323,150,1425,721
|
-0.46011623230476806,1.2276781392572151,1.4304282132683406,-0.51839569402218,0.5210982679469837,-0.19785570229010588,0.015103007549675692,0.5210982679469837,-0.30834940175024095,3.6703575558394306,-0.09007741527544748,-0.07237000350541305,-0.3835820044684915,0.0667537675442864,0.42772059381643684,0.7312843575943586,-0.5379930941294808,-0.8217731668728108,-0.30834940175024095,-0.3458054921469844,-0.16163385385214332,1.06873759915191,-0.1436346549150024,-0.0022514235063176217,0.20154814096271612,0.28370179506564897,0.7312843575943586,-0.3835820044684915,2.079509582008797,0.411956352337547,2.5349567864503544,0.4434266881560912,-0.019675434888960938,-0.6172554898593413,-0.10785697374131768,0.10084869034597146,0.4434266881560912,1.5998828218041645,0.20154814096271612,1.3176250631188255,2.1316806866838474,-0.1436346549150024,1.7851784018367542,-0.19785570229010588,0.31612783470675104
| 2,702
|
MFS transporter superfamily [IPR036259]
| 7
| 9
| 1.987082
| 0.046913
|
P11166,O00400,Q96ES6,Q6NT16,P41440,P53985,Q9H2V7
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
539,264,169,44,271,244,346
|
264,539,271,244,2109,44,169,558,346
|
1.2146655480675908,0.536463418458696,1.188515758083854,1.2921274336650987,-0.5774483420396528,2.88278106126926,1.6235191019297979,0.5210982679469837,0.97311149261789
| 2,702
|
oxidase
| 6
| 11
| 1.98489
| 0.047157
|
Q8NB78,P14406,Q6ZRP7,P20674,P13073,Q15800
|
Functions
|
Panther Protein class
|
panther_protein_class
|
195,7,424,405,337,283
|
1169,497,1250,337,7,2072,405,1610,283,424,195
|
-0.05473421435229654,0.6124633021363719,-0.10785697374131768,0.9869083646757261,3.792063109742703,-0.5576770803133537,0.8182439888074761,-0.30834940175024095,1.148975957368919,0.7749899149252996,1.4917673289663298
| 2,702
|
Horizontal nystagmus
| 9
| 20
| 1.97941
| 0.04777
|
O60313,P04062,P50542,Q9NSE4,P07602,Q9NZJ7,O94905,O95831,O14773
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
416,134,490,172,13,336,180,313,157
|
1031,744,157,538,416,180,313,134,13,780,1649,490,1720,1722,1986,1988,2478,172,336,2033
|
0.03238835570877815,0.2673963211845321,1.7166949344659548,0.536463418458696,0.7894576895397357,1.5641657435116996,1.055211388917935,1.90774847949041,3.6358051961034,0.2345983492140732,-0.3270376997249967,0.6275005747563835,-0.3646533883592373,-0.3646533883592373,-0.4988841983587244,-0.4988841983587244,-0.9276215217752557,1.6117183489592206,1.0006594538170546,-0.51839569402218
| 2,702
|
Sphingolipid biosynthetic process
| 6
| 14
| 1.97722
| 0.048017
|
P04062,O95470,Q96G23,Q13510,Q99805,Q06136
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
134,107,301,55,251,189
|
495,1533,107,134,582,189,55,2614,1313,301,251,1165,312,1524
|
0.6124633021363719,-0.2712088850102407,2.0899995453915405,1.90774847949041,0.4746659679952571,1.5160447795129783,2.6994624661868474,-1.307106361795847,-0.1436346549150024,1.1090521543190752,1.2793186260964378,-0.03716952921365007,1.06873759915191,-0.2527554805154473
| 2,702
|
Hepatic failure
| 18
| 40
| 1.972572
| 0.048544
|
O43772,Q10713,P04062,O15118,Q16822,Q9Y619,Q6NUQ1,P50542,Q6PGP7,P38571,Q9Y2R9,Q8IWV7,Q13510,P22830,P40855,O15460,O75381,P23786
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
162,453,134,69,329,351,633,490,584,525,597,144,55,281,314,220,319,63
|
69,220,162,2275,319,650,2315,134,1602,1036,875,919,281,63,1086,2621,525,314,1463,2467,1835,490,2376,1583,453,1180,55,329,785,633,584,144,1418,1163,1217,1295,1777,597,1220,351
|
2.497417369060405,1.3806795740768194,1.6820076128894363,-0.7183505049899396,1.0416407333608675,0.38025187320722004,-0.759434892091634,1.90774847949041,-0.30834940175024095,0.03238835570877815,0.15149219850709802,0.11779590878562075,1.148975957368919,2.5721316468788222,-0.0022514235063176217,-1.3538870822211624,0.5670274774060957,1.055211388917935,-0.23437919882369965,-0.9276215217752557,-0.4216838952161537,0.6275005747563835,-0.8008978009850447,-0.2897399955466822,0.7166140404526318,-0.05473421435229654,2.6994624661868474,1.0143650321652233,0.2345983492140732,0.411956352337547,0.4746659679952571,1.807747107129735,-0.19785570229010588,-0.03716952921365007,-0.07237000350541305,-0.1257092085342695,-0.3835820044684915,0.4590750194134483,-0.07237000350541305,0.9592685631657338
| 2,702
|
Intrinsic component of organelle membrane
| 45
| 111
| 4.746268
| 0.000002
|
Q99595,Q8TB61,Q8N2H4,Q9BUR5,O95070,Q9Y4P3,Q9Y2R0,O75844,O95470,O75880,O43505,Q13505,Q9BUN8,Q9P2E9,Q9UH99,P10321,Q15629,Q16891,P57105,Q14739,Q9BPX6,Q9NQC3,Q96A33,P42892,Q9UKV5,Q9Y282,O15118,Q9P035,Q8TCT9,Q8N4V1,Q15070,O43808,O14925,P51572,Q9NX63,Q6P4A7,Q9UBM7,Q8TB36,Q86XL3,Q53H12,Q15388,O75431,Q8TCT8,Q8IWA4,Q6ZRP7
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,258,132,393,386,528,14,147,275,529,282,156,413,428,560,423,43,555,431,175,303,308,442,55,568,62,63,455,77,79,85,337,344,469,350,97,359,484,102,237,366,499,118,373,505
|
636,1319,973,344,63,2022,1453,1122,282,337,499,147,529,1174,1225,386,275,1151,785,2487,423,978,1199,1022,1232,1998,1408,1302,2318,55,1410,469,649,431,1412,1563,1278,2115,1062,1084,156,1440,175,927,85,366,43,845,2556,555,237,869,726,963,97,1089,505,620,102,713,373,995,1981,132,79,1419,1660,484,258,118,77,2468,659,442,2427,1503,1447,2,303,1372,1538,765,413,393,1139,968,1629,1509,896,1245,1095,308,808,350,1247,455,969,428,359,1117,1844,560,568,1376,62,14,581,528,783,663,1515
|
0.4560011507642696,-0.14556179771058245,0.09320779573109034,0.9612662003264605,2.472830381816948,-0.5492740993843713,-0.22738159228350283,-0.017000063987738737,1.1855852561088989,0.9747001337238531,0.6576886443457405,1.858096452664984,0.6007678594820233,-0.04887504627384466,-0.08092564237043719,0.8800131050184969,1.1985189212016558,-0.032915728384741015,0.2622891279230963,-1.0021412347204408,0.7976231963964028,0.09320779573109034,-0.0648782670729416,0.061932036437784624,-0.08092564237043719,-0.5318785727630885,-0.19451519653859392,-0.12933524422973913,-0.7803189764195482,2.5660054539144865,-0.19451519653859392,0.7140629338857863,0.4413258066063131,0.7837786881907414,-0.19451519653859392,-0.27703285170862874,-0.11315387381905866,-0.6017771358819511,0.030487470396744938,0.014701291299391921,1.7883210270224281,-0.21092513401942328,1.658237345935038,0.13980900706892938,2.314254726861213,0.9207797152191141,2.7878758792557337,0.21665972726603153,-1.1356055001499545,0.5720990698697436,1.3263238911225568,0.2013703373493341,0.3375549865593367,0.10878295888408213,2.217058138603211,0.014701291299391921,0.6435101106197167,0.48524197874422104,2.1623710072700724,0.35249256146592,0.9072221686279333,0.09320779573109034,-0.514535240785251,1.94987853311504,2.3463066784162883,-0.19451519653859392,-0.3271128392759249,0.6859434192423728,1.275532592400303,2.0065339889232616,2.3569527332268905,-0.9645715603540274,0.42661358757948437,0.7699015142883784,-0.9086735477231258,-0.243884846085324,-0.21092513401942328,4.084595663215114,1.1073832487263275,-0.1618337970909173,-0.26043517265107846,0.2925118928589216,0.8252148517366122,0.8800131050184969,-0.017000063987738737,0.10878295888408213,-0.31037139890127774,-0.243884846085324,0.17067086843316673,-0.08092564237043719,0.014701291299391921,1.0942483489073807,0.24711890736266962,0.9612662003264605,-0.08092564237043719,0.7559915142019157,0.10878295888408213,0.7976231963964028,0.9478015835630615,-0.001127805810301048,-0.4285902586631195,0.5720990698697436,0.5577119571515898,-0.1618337970909173,2.4832547399290448,3.497184563628806,0.5432894598416556,0.6150498919054735,0.2774200528143013,0.42661358757948437,-0.243884846085324
| 2,702
|
Ion transmembrane transporter activity
| 49
| 98
| 4.548083
| 0.000005
|
O15439,Q70HW3,Q8TB61,P21796,P13073,P33527,P53985,Q9UBX3,Q9BQT8,Q96ES6,Q8NEW0,Q7KZN9,Q9C0H2,P45880,P05023,Q9UJS0,Q9Y5K8,Q96QD8,Q9Y487,Q9Y6M7,Q9Y277,Q9H2D1,O75964,P16615,P20674,P25705,Q9HD20,P56134,Q9H2H9,P41440,Q8N4V1,Q93050,O43772,O43808,P00403,Q9UDW1,P06576,O43681,Q9BXP2,Q9Y619,Q6P4A7,O00400,O95202,P12236,P51790,P24539,Q99808,Q13423,P04920
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
380,1,258,11,395,13,271,144,146,279,152,409,31,34,539,420,561,559,41,304,437,53,184,441,572,451,69,573,198,457,79,82,83,337,338,87,215,467,609,226,97,352,363,614,242,371,633,119,502
|
2055,352,380,467,83,337,921,1992,184,363,1151,338,502,539,1252,860,215,1229,1323,1057,1230,1175,889,978,614,395,441,1022,572,1101,2406,11,941,371,451,2197,13,1614,1082,1876,457,34,2508,1969,242,1463,271,573,904,841,1563,1278,2115,1159,119,1028,1415,760,2657,642,1443,97,1,409,79,1660,152,258,1475,2348,82,2427,279,1503,559,669,633,146,609,31,1215,53,198,1629,896,69,144,87,1217,420,1376,437,1805,41,561,226,2549,304
|
-0.566722147958878,0.9478015835630615,0.8936333486288025,0.7140629338857863,2.3249577453845984,0.9747001337238531,0.13980900706892938,-0.5318785727630885,1.586065401491409,0.9207797152191141,-0.032915728384741015,0.9747001337238531,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,1.4017035243632918,-0.08092564237043719,-0.14556179771058245,0.030487470396744938,-0.08092564237043719,-0.04887504627384466,0.17067086843316673,0.09320779573109034,0.48524197874422104,0.8663612864956289,0.7699015142883784,0.061932036437784624,0.5432894598416556,-0.001127805810301048,-0.8901609796463711,3.541068752096914,0.12431661965225804,0.9072221686279333,0.7559915142019157,-0.6725321288961622,3.497184563628806,-0.31037139890127774,0.014701291299391921,-0.462815185693309,0.7420485262435965,2.953902538225382,-1.0399582580540272,-0.514535240785251,1.3136668502909221,-0.22738159228350283,1.211424359795403,0.5432894598416556,0.1552603482535626,0.21665972726603153,-0.27703285170862874,-0.11315387381905866,-0.6017771358819511,-0.032915728384741015,1.9952458014491112,0.061932036437784624,-0.19451519653859392,0.2925118928589216,-1.6183674545716196,0.4560011507642696,-0.21092513401942328,2.217058138603211,4.343126506682812,0.8389623139505717,2.3463066784162883,-0.3271128392759249,1.8349285964616746,1.275532592400303,-0.22738159228350283,-0.8167006259673601,2.3356417057869807,-0.9086735477231258,1.1985189212016558,-0.243884846085324,0.5720990698697436,0.41186430071853863,0.4706398114973275,1.8696467178692489,0.4998078409542412,2.9827338068802134,-0.0648782670729416,2.5967459172501477,1.4884520937953238,-0.31037139890127774,0.17067086843316673,2.4309512128450095,1.8811746612706568,2.303532579472338,-0.0648782670729416,0.8114351982042777,-0.1618337970909173,0.7837786881907414,-0.4115533912456994,2.8371826720644844,0.5720990698697436,1.3766833583434828,-1.1163480492502467,1.1073832487263275
| 2,702
|
Transporter activity
| 61
| 161
| 4.3887
| 0.000011
|
Q9NS69,Q70HW3,Q99595,Q8TB61,O15439,P51991,P21796,P13073,P33527,P53985,Q9UBX3,Q9Y5J9,Q9BQT8,O43676,Q96ES6,Q8NEW0,Q9H2V7,Q7KZN9,Q9C0H2,O15173,P45880,P17900,P30536,Q6NT16,Q9UJS0,Q9Y487,Q9Y6M7,Q9Y277,Q9H2D1,P08183,O75964,O75027,P16615,P04062,Q8IXU6,O15118,P25705,Q8WTV0,Q9HD20,Q9H2H9,Q8N4V1,Q93050,O43772,O43808,P38435,P00403,Q9UDW1,P06576,O14925,Q9Y619,Q6P4A7,Q9H4L5,O00400,Q15388,O95202,P51790,Q9P0J0,P24539,Q13423,P61916,O96000
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,1,2,258,380,390,11,395,13,271,144,400,146,20,279,152,153,409,31,33,34,162,289,37,420,41,304,437,53,54,184,312,441,188,61,63,451,324,69,198,79,82,83,337,86,338,87,215,344,226,97,358,352,366,363,242,375,371,119,248,369
|
1319,2687,2055,352,1586,344,63,33,380,20,1895,467,83,337,312,2531,1608,1322,921,1992,184,1225,1517,731,592,1787,363,2088,1151,369,785,338,188,502,539,1252,860,215,1229,1323,54,1057,1230,1175,889,978,614,395,441,162,2465,1022,572,1101,2406,11,1555,941,371,451,615,2418,289,2197,13,1614,1082,86,1876,457,34,2508,1765,701,1969,2642,242,1463,1680,390,1526,271,573,904,841,1563,248,1278,2115,2567,1159,988,119,1942,1028,366,1415,2290,1944,760,2657,37,642,1443,97,1,409,61,79,567,714,521,1660,152,258,1475,324,2348,82,2427,279,1503,559,669,2047,707,2,764,633,1601,146,1698,609,1784,31,1215,53,198,153,358,1629,896,69,0,375,144,87,674,1217,420,1376,1098,437,1805,41,400,561,226,2549,304,953
|
-0.14556179771058245,-2.830790652033712,-0.566722147958878,0.9478015835630615,-0.29367816551779385,0.9612662003264605,2.472830381816948,2.953902538225382,0.8936333486288025,3.1993280187186217,-0.4800038669191164,0.7140629338857863,2.3249577453845984,0.9747001337238531,1.0678905729851498,-1.0971550435827746,-0.31037139890127774,-0.14556179771058245,0.13980900706892938,-0.5318785727630885,1.586065401491409,-0.08092564237043719,-0.26043517265107846,0.32257915315367963,0.5143375851029162,-0.4115533912456994,0.9207797152191141,-0.5842230489234069,-0.032915728384741015,0.9072221686279333,0.2622891279230963,0.9747001337238531,1.549648138953408,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,1.4017035243632918,-0.08092564237043719,-0.14556179771058245,2.5762697271805473,0.030487470396744938,-0.08092564237043719,-0.04887504627384466,0.17067086843316673,0.09320779573109034,0.48524197874422104,0.8663612864956289,0.7699015142883784,1.7295441678744543,-0.9645715603540274,0.061932036437784624,0.5432894598416556,-0.001127805810301048,-0.8901609796463711,3.541068752096914,-0.27703285170862874,0.12431661965225804,0.9072221686279333,0.7559915142019157,0.48524197874422104,-0.9086735477231258,1.1596327314267856,-0.6725321288961622,3.497184563628806,-0.31037139890127774,0.014701291299391921,2.303532579472338,-0.462815185693309,0.7420485262435965,2.953902538225382,-1.0399582580540272,-0.3945665116133365,0.3673920803157548,-0.514535240785251,-1.5143718566673,1.3136668502909221,-0.22738159228350283,-0.3439027766845685,0.8800131050184969,-0.26043517265107846,1.211424359795403,0.5432894598416556,0.1552603482535626,0.21665972726603153,-0.27703285170862874,1.3009827009421377,-0.11315387381905866,-0.6017771358819511,-1.174315546728808,-0.032915728384741015,0.09320779573109034,1.9952458014491112,-0.4972437792285436,0.061932036437784624,0.9207797152191141,-0.19451519653859392,-0.7441656379825385,-0.4972437792285436,0.2925118928589216,-1.6183674545716196,2.886090180376803,0.4560011507642696,-0.21092513401942328,2.217058138603211,4.343126506682812,0.8389623139505717,2.4832547399290448,2.3463066784162883,0.5577119571515898,0.35249256146592,0.6150498919054735,-0.3271128392759249,1.8349285964616746,1.275532592400303,-0.22738159228350283,1.0281319155612654,-0.8167006259673601,2.3356417057869807,-0.9086735477231258,1.1985189212016558,-0.243884846085324,0.5720990698697436,0.41186430071853863,-0.5492740993843713,0.3673920803157548,4.084595663215114,0.2925118928589216,0.4706398114973275,-0.29367816551779385,1.8696467178692489,-0.3439027766845685,0.4998078409542412,-0.3945665116133365,2.9827338068802134,-0.0648782670729416,2.5967459172501477,1.4884520937953238,1.8349285964616746,0.9478015835630615,-0.31037139890127774,0.17067086843316673,2.4309512128450095,4.48719359410752,0.9072221686279333,1.8811746612706568,2.303532579472338,0.41186430071853863,-0.0648782670729416,0.8114351982042777,-0.1618337970909173,0.014701291299391921,0.7837786881907414,-0.4115533912456994,2.8371826720644844,0.8663612864956289,0.5720990698697436,1.3766833583434828,-1.1163480492502467,1.1073832487263275,0.12431661965225804
| 2,702
|
Lysosomal lumen
| 22
| 32
| 4.338623
| 0.000014
|
P50897,O00584,P07602,Q8NHP8,Q8IV08,O14773,Q13510,Q14108,P08236,P07686,P17900,P10619,P54802,P04062,P38435,P06865,P10253,P16278,P15586,P06280,P11117,Q99538
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
3,131,4,10,19,150,26,29,158,160,162,38,50,188,86,92,220,93,221,112,113,121
|
131,2672,150,467,188,439,112,92,4,160,1551,158,220,38,113,1589,221,93,162,86,389,3,50,248,26,29,19,1534,10,121,782,427
|
1.94987853311504,-1.9200896765948166,1.8349285964616746,0.7140629338857863,1.549648138953408,0.7699015142883784,2.040271181152975,2.249632405350508,4.00405433878558,1.7531245573462935,-0.27703285170862874,1.7648798340833782,1.3892066414158972,2.8665746612984697,2.040271181152975,-0.29367816551779385,1.3892066414158972,2.2387939765464413,1.7295441678744543,2.303532579472338,0.8800131050184969,4.03639791939681,2.6577600342457113,1.3009827009421377,3.0114283478612625,3.0018786097104724,3.2085718590601604,-0.26043517265107846,3.5759499600620965,1.9952458014491112,0.2774200528143013,0.7976231963964028
| 2,702
|
Vacuolar lumen
| 26
| 60
| 4.30895
| 0.000016
|
P50897,O00584,P07602,Q8NHP8,Q8IV08,O14773,Q13510,Q92820,Q14108,P08236,P07686,P17900,P10619,P54802,P04062,P07437,P38435,P68371,P06865,P10253,P15586,P16278,P06280,P11117,P61916,Q99538
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
3,131,4,10,19,150,26,284,29,158,160,162,38,50,188,211,86,216,92,220,221,93,112,113,248,121
|
637,131,2672,150,467,2431,188,439,112,92,1229,211,4,160,1551,158,220,38,113,1589,1059,221,93,162,1023,2544,86,389,564,3,2070,2177,1157,50,2094,2331,248,216,824,2567,1972,463,26,29,1769,19,1534,10,284,965,2082,460,121,2309,307,782,635,2620,427,2210
|
0.4560011507642696,1.94987853311504,-1.9200896765948166,1.8349285964616746,0.7140629338857863,-0.9272458982666049,1.549648138953408,0.7699015142883784,2.040271181152975,2.249632405350508,-0.08092564237043719,1.4266185504356594,4.00405433878558,1.7531245573462935,-0.27703285170862874,1.7648798340833782,1.3892066414158972,2.8665746612984697,2.040271181152975,-0.29367816551779385,0.030487470396744938,1.3892066414158972,2.2387939765464413,1.7295441678744543,0.061932036437784624,-1.1163480492502467,2.303532579472338,0.8800131050184969,0.5577119571515898,4.03639791939681,-0.566722147958878,-0.6547618971329058,-0.032915728384741015,2.6577600342457113,-0.5842230489234069,-0.7984810752691569,1.3009827009421377,1.4017035243632918,0.23190917857868676,-1.174315546728808,-0.514535240785251,0.7280723875131836,3.0114283478612625,3.0018786097104724,-0.3945665116133365,3.2085718590601604,-0.26043517265107846,3.5759499600620965,1.1855852561088989,0.10878295888408213,-0.566722147958878,0.7420485262435965,1.9952458014491112,-0.7622139544215649,1.0942483489073807,0.2774200528143013,0.4706398114973275,-1.3518233822249164,0.7976231963964028,-0.6725321288961622
| 2,702
|
Anion transport
| 36
| 66
| 4.200446
| 0.000027
|
O15439,Q8TB61,P07602,P21796,P33527,Q9H0H5,P53985,Q9UBX3,Q9HD26,Q9BQT8,Q9C0H2,Q9UHG3,P30536,P45880,Q9UJS0,Q96QD8,Q9NZJ7,Q9Y6M7,Q9Y277,Q9H2D1,P08183,O43865,Q9H2H9,P41440,O43808,O43681,Q15907,Q9BXP2,Q9Y619,O00400,P28288,P12236,P51790,Q99808,P14174,P04920
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
380,258,4,11,13,270,271,144,538,146,31,32,289,34,420,559,427,304,437,53,54,196,198,457,337,467,477,609,226,352,615,614,242,633,122,502
|
2055,352,380,467,337,196,921,1637,1151,818,502,860,957,4,54,1057,889,978,614,122,1233,11,615,289,13,457,34,1969,242,1463,271,787,2115,1159,757,1415,477,760,2657,642,1443,258,1475,1503,559,669,633,146,609,31,270,53,198,1629,896,538,427,144,32,420,437,1805,1545,226,2549,304
|
-0.566722147958878,0.9478015835630615,0.8936333486288025,0.7140629338857863,0.9747001337238531,1.4884520937953238,0.13980900706892938,-0.3271128392759249,-0.032915728384741015,0.23190917857868676,0.6435101106197167,0.2013703373493341,0.10878295888408213,4.00405433878558,2.5762697271805473,0.030487470396744938,0.17067086843316673,0.09320779573109034,0.48524197874422104,1.983936246561302,-0.08092564237043719,3.541068752096914,0.48524197874422104,1.1596327314267856,3.497184563628806,0.7420485262435965,2.953902538225382,-0.514535240785251,1.3136668502909221,-0.22738159228350283,1.211424359795403,0.2622891279230963,-0.6017771358819511,-0.032915728384741015,0.2925118928589216,-0.19451519653859392,0.700019999999374,0.2925118928589216,-1.6183674545716196,0.4560011507642696,-0.21092513401942328,1.275532592400303,-0.22738159228350283,-0.243884846085324,0.5720990698697436,0.41186430071853863,0.4706398114973275,1.8696467178692489,0.4998078409542412,2.9827338068802134,1.224301699534718,2.5967459172501477,1.4884520937953238,-0.31037139890127774,0.17067086843316673,0.6007678594820233,0.7976231963964028,1.8811746612706568,2.9731386427052393,0.8114351982042777,0.7837786881907414,-0.4115533912456994,-0.26043517265107846,1.3766833583434828,-1.1163480492502467,1.1073832487263275
| 2,702
|
Lysosome
| 30
| 45
| 4.1692
| 0.000031
|
Q9Y2T2,P50897,P07602,P38571,P11279,O14773,Q13510,Q14108,P08236,P07686,P11717,P17900,P10619,Q9NZJ7,Q9Y487,P54802,P04062,P04066,O15118,O75503,Q93050,O43681,P06865,P10253,P15586,P16278,P06280,P11117,P61916,Q99538
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
394,3,4,389,387,150,26,29,158,160,417,162,38,427,41,50,188,439,63,206,82,467,92,220,221,93,112,113,248,121
|
2148,2672,2516,150,63,467,1959,206,188,439,112,92,4,160,158,976,977,220,38,113,387,417,221,93,162,1676,389,3,50,841,248,2035,1494,26,29,488,643,2604,82,121,1169,427,1217,394,41
|
-0.6370462182791121,-1.9200896765948166,-1.0589605873257606,1.8349285964616746,2.472830381816948,0.7140629338857863,-0.514535240785251,1.4514293500729303,1.549648138953408,0.7699015142883784,2.040271181152975,2.249632405350508,4.00405433878558,1.7531245573462935,1.7648798340833782,0.09320779573109034,0.09320779573109034,1.3892066414158972,2.8665746612984697,2.040271181152975,0.8800131050184969,0.8114351982042777,1.3892066414158972,2.2387939765464413,1.7295441678744543,-0.3439027766845685,0.8800131050184969,4.03639791939681,2.6577600342457113,0.21665972726603153,1.3009827009421377,-0.5492740993843713,-0.243884846085324,3.0114283478612625,3.0018786097104724,0.6718330237408522,0.4560011507642696,-1.2920402919692853,2.3356417057869807,1.9952458014491112,-0.032915728384741015,0.7976231963964028,-0.0648782670729416,0.8800131050184969,2.8371826720644844
| 2,702
|
Vacuolar membrane
| 38
| 105
| 3.872209
| 0.000108
|
Q92542,Q9Y2T2,P07602,P11279,P42785,Q9BTU6,Q8NF37,Q9HD26,Q8IV08,Q9H2V7,Q14108,O60271,Q9Y5K8,P10619,Q9H0B6,Q9Y487,Q8IY95,Q9NZJ7,O75955,Q07065,Q8NB49,P42892,P04062,Q9UIQ6,O15118,Q8WTV0,P41440,O75503,Q93050,O15400,P10253,Q9P253,O95721,O15260,P11117,P51790,Q8TCT8,O43633
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
519,394,4,387,12,399,405,538,19,153,29,157,561,38,426,41,558,427,422,179,567,55,188,64,63,324,457,206,82,475,220,486,353,109,113,242,118,501
|
2148,2516,63,109,475,501,1959,157,1267,1321,206,422,2212,353,1961,188,1228,1229,4,1323,1057,1298,1380,976,220,38,113,1589,387,1676,1101,2406,2505,1558,593,1082,1876,2000,457,604,12,55,2434,1969,1525,1410,242,1463,756,985,1006,823,1905,841,1940,2035,2159,179,1715,1767,1494,29,1281,19,558,567,405,118,324,1394,914,519,82,1370,804,780,792,1601,399,1169,1699,426,1215,1578,1244,153,2627,1051,538,934,427,2051,1484,486,2470,1217,64,2250,1926,1001,394,569,1016,41,561
|
-0.6370462182791121,-1.0589605873257606,2.472830381816948,2.0626573264796644,0.700019999999374,0.6435101106197167,-0.514535240785251,1.776611959141398,-0.11315387381905866,-0.14556179771058245,1.4514293500729303,0.7976231963964028,-0.6903572636353332,0.9478015835630615,-0.514535240785251,1.549648138953408,-0.08092564237043719,-0.08092564237043719,4.00405433878558,-0.14556179771058245,0.030487470396744938,-0.12933524422973913,-0.17815150752877743,0.09320779573109034,1.3892066414158972,2.8665746612984697,2.040271181152975,-0.29367816551779385,0.8800131050184969,-0.3439027766845685,-0.001127805810301048,-0.8901609796463711,-1.0399582580540272,-0.27703285170862874,0.5143375851029162,0.014701291299391921,-0.462815185693309,-0.5318785727630885,0.7420485262435965,0.4998078409542412,3.523552992410392,2.5660054539144865,-0.9272458982666049,-0.514535240785251,-0.26043517265107846,-0.19451519653859392,1.3136668502909221,-0.22738159228350283,0.2925118928589216,0.09320779573109034,0.07759089922445578,0.23190917857868676,-0.4800038669191164,0.21665972726603153,-0.4972437792285436,-0.5492740993843713,-0.6370462182791121,1.6222608747574856,-0.36074150382824394,-0.3945665116133365,-0.243884846085324,3.0018786097104724,-0.11315387381905866,3.2085718590601604,0.5720990698697436,0.5577119571515898,0.852677740649789,2.0065339889232616,1.0281319155612654,-0.17815150752877743,0.1552603482535626,0.6292972508241202,2.3356417057869807,-0.1618337970909173,0.24711890736266962,0.2774200528143013,0.2622891279230963,-0.29367816551779385,0.8663612864956289,-0.032915728384741015,-0.3439027766845685,0.7976231963964028,-0.0648782670729416,-0.27703285170862874,-0.08092564237043719,1.8349285964616746,-1.4122382294877622,0.04623097246479662,0.6007678594820233,0.13980900706892938,0.7976231963964028,-0.5492740993843713,-0.22738159228350283,0.6859434192423728,-0.9645715603540274,-0.0648782670729416,2.472830381816948,-0.7082376548394596,-0.4800038669191164,0.09320779573109034,0.8800131050184969,0.5577119571515898,0.07759089922445578,2.8371826720644844,0.5720990698697436
| 2,702
|
Vacuole
| 73
| 187
| 3.775488
| 0.00016
|
Q92542,Q9Y2T2,P50897,P07602,O00584,P38571,P11279,Q8NHP8,P42785,Q9BTU6,Q8NF37,Q9HD26,Q8IV08,Q9H2V7,O14773,P09622,Q13510,P00813,Q92820,Q14108,O60271,P08236,Q9UHG3,P07686,Q9NX40,P17900,Q9Y5K8,P10619,Q9H0B6,Q9Y487,Q8IY95,Q9NZJ7,O75955,Q5BJF2,Q01085,P54802,Q07065,P50395,Q9BTY2,Q8NB49,P42892,P04062,P04066,Q9UIQ6,O15118,Q8WTV0,P41440,Q99536,O75503,Q13217,Q93050,P07437,P38435,P68371,O43681,O15400,P06865,P16278,Q15165,P10253,P15586,Q9P253,Q969Q5,O95721,O15260,P06280,P11117,P51790,Q8TCT8,P61916,Q99538,O43633,P19474
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
519,394,3,4,131,389,387,10,12,399,405,538,19,153,150,25,26,27,284,29,157,158,32,160,411,162,561,38,426,41,558,427,422,47,552,50,179,564,307,567,55,188,439,64,63,324,457,460,206,463,82,211,86,216,467,475,92,93,94,220,221,486,485,353,109,112,113,242,118,248,121,501,381
|
2352,2148,637,131,2672,2516,150,699,63,109,475,1146,501,467,1959,157,689,1267,1321,2430,206,422,2212,353,1961,2431,27,188,439,1228,112,92,1229,2327,211,4,160,1551,1323,1057,158,1298,1380,976,25,220,38,113,1589,1059,387,221,93,162,381,1676,1101,2406,2505,2408,1998,1023,2544,1558,593,1082,86,389,1876,2000,457,604,12,1740,55,1130,2434,1969,564,720,3,2070,630,1525,1410,1201,242,1463,2177,756,1157,50,2094,985,1006,2283,823,1905,2331,841,248,1940,216,824,2035,552,2567,1972,1882,2159,179,1715,1767,1494,788,2220,463,26,880,29,1769,94,47,1281,19,558,567,1534,643,405,10,118,324,1394,914,519,284,82,485,965,1370,804,780,2082,460,121,1836,792,1601,2309,399,307,782,1169,1699,426,1215,1578,1244,153,635,2627,1051,538,611,411,934,2620,427,2051,1484,486,686,2470,32,1217,64,2250,1926,1001,2210,394,569,1016,41,561,1515
|
-0.8349780072652183,-0.6370462182791121,0.4560011507642696,1.94987853311504,-1.9200896765948166,-1.0589605873257606,1.8349285964616746,0.3673920803157548,2.472830381816948,2.0626573264796644,0.700019999999374,-0.032915728384741015,0.6435101106197167,0.7140629338857863,-0.514535240785251,1.776611959141398,0.382253743928895,-0.11315387381905866,-0.14556179771058245,-0.9272458982666049,1.4514293500729303,0.7976231963964028,-0.6903572636353332,0.9478015835630615,-0.514535240785251,-0.9272458982666049,3.0018786097104724,1.549648138953408,0.7699015142883784,-0.08092564237043719,2.040271181152975,2.249632405350508,-0.08092564237043719,-0.7984810752691569,1.4266185504356594,4.00405433878558,1.7531245573462935,-0.27703285170862874,-0.14556179771058245,0.030487470396744938,1.7648798340833782,-0.12933524422973913,-0.17815150752877743,0.09320779573109034,3.0399875010519266,1.3892066414158972,2.8665746612984697,2.040271181152975,-0.29367816551779385,0.030487470396744938,0.8800131050184969,1.3892066414158972,2.2387939765464413,1.7295441678744543,0.8936333486288025,-0.3439027766845685,-0.001127805810301048,-0.8901609796463711,-1.0399582580540272,-0.8901609796463711,-0.5318785727630885,0.061932036437784624,-1.1163480492502467,-0.27703285170862874,0.5143375851029162,0.014701291299391921,2.303532579472338,0.8800131050184969,-0.462815185693309,-0.5318785727630885,0.7420485262435965,0.4998078409542412,3.523552992410392,-0.377629316099032,2.5660054539144865,-0.017000063987738737,-0.9272458982666049,-0.514535240785251,0.5577119571515898,0.3375549865593367,4.03639791939681,-0.566722147958878,0.4706398114973275,-0.26043517265107846,-0.19451519653859392,-0.0648782670729416,1.3136668502909221,-0.22738159228350283,-0.6547618971329058,0.2925118928589216,-0.032915728384741015,2.6577600342457113,-0.5842230489234069,0.09320779573109034,0.07759089922445578,-0.7441656379825385,0.23190917857868676,-0.4800038669191164,-0.7984810752691569,0.21665972726603153,1.3009827009421377,-0.4972437792285436,1.4017035243632918,0.23190917857868676,-0.5492740993843713,0.5720990698697436,-1.174315546728808,-0.514535240785251,-0.462815185693309,-0.6370462182791121,1.6222608747574856,-0.36074150382824394,-0.3945665116133365,-0.243884846085324,0.2622891279230963,-0.6903572636353332,0.7280723875131836,3.0114283478612625,0.18604079096340007,3.0018786097104724,-0.3945665116133365,2.2387939765464413,2.7381629713773825,-0.11315387381905866,3.2085718590601604,0.5720990698697436,0.5577119571515898,-0.26043517265107846,0.4560011507642696,0.852677740649789,3.5759499600620965,2.0065339889232616,1.0281319155612654,-0.17815150752877743,0.1552603482535626,0.6292972508241202,1.1855852561088989,2.3356417057869807,0.6859434192423728,0.10878295888408213,-0.1618337970909173,0.24711890736266962,0.2774200528143013,-0.566722147958878,0.7420485262435965,1.9952458014491112,-0.4285902586631195,0.2622891279230963,-0.29367816551779385,-0.7622139544215649,0.8663612864956289,1.0942483489073807,0.2774200528143013,-0.032915728384741015,-0.3439027766845685,0.7976231963964028,-0.0648782670729416,-0.27703285170862874,-0.08092564237043719,1.8349285964616746,0.4706398114973275,-1.4122382294877622,0.04623097246479662,0.6007678594820233,0.4998078409542412,0.8389623139505717,0.13980900706892938,-1.3518233822249164,0.7976231963964028,-0.5492740993843713,-0.22738159228350283,0.6859434192423728,0.39707775152061925,-0.9645715603540274,2.9731386427052393,-0.0648782670729416,2.472830381816948,-0.7082376548394596,-0.4800038669191164,0.09320779573109034,-0.6725321288961622,0.8800131050184969,0.5577119571515898,0.07759089922445578,2.8371826720644844,0.5720990698697436,-0.243884846085324
| 2,702
|
Cation transmembrane transporter activity
| 30
| 68
| 3.773528
| 0.000161
|
Q70HW3,P13073,Q96ES6,Q8NEW0,Q7KZN9,P05023,Q9Y5K8,Q96QD8,Q9Y487,Q9Y6M7,O75964,P16615,P20674,P25705,P56134,Q9H2H9,Q9HD20,Q8N4V1,Q93050,O43772,O43808,P00403,Q9UDW1,P06576,Q9Y619,O00400,O95202,P51790,P24539,Q13423
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
1,395,279,152,409,539,561,559,41,304,184,441,572,451,573,198,69,79,82,83,337,338,87,215,226,352,363,242,371,119
|
352,83,337,1992,184,363,338,539,1252,860,215,1229,1323,1057,1230,1175,978,395,441,1022,572,1101,2406,941,371,451,2197,1614,1082,1876,2508,1969,242,573,904,841,1563,1278,2115,119,1415,760,1,409,79,1660,152,2348,82,2427,279,1503,559,633,609,1215,198,1629,896,69,87,1217,1376,1805,41,561,226,304
|
0.9478015835630615,2.3249577453845984,0.9747001337238531,-0.5318785727630885,1.586065401491409,0.9207797152191141,0.9747001337238531,0.5864509778300103,-0.09701742595051951,0.2013703373493341,1.4017035243632918,-0.08092564237043719,-0.14556179771058245,0.030487470396744938,-0.08092564237043719,-0.04887504627384466,0.09320779573109034,0.8663612864956289,0.7699015142883784,0.061932036437784624,0.5432894598416556,-0.001127805810301048,-0.8901609796463711,0.12431661965225804,0.9072221686279333,0.7559915142019157,-0.6725321288961622,-0.31037139890127774,0.014701291299391921,-0.462815185693309,-1.0399582580540272,-0.514535240785251,1.3136668502909221,0.5432894598416556,0.1552603482535626,0.21665972726603153,-0.27703285170862874,-0.11315387381905866,-0.6017771358819511,1.9952458014491112,-0.19451519653859392,0.2925118928589216,4.343126506682812,0.8389623139505717,2.3463066784162883,-0.3271128392759249,1.8349285964616746,-0.8167006259673601,2.3356417057869807,-0.9086735477231258,1.1985189212016558,-0.243884846085324,0.5720990698697436,0.4706398114973275,0.4998078409542412,-0.0648782670729416,1.4884520937953238,-0.31037139890127774,0.17067086843316673,2.4309512128450095,2.303532579472338,-0.0648782670729416,-0.1618337970909173,-0.4115533912456994,2.8371826720644844,0.5720990698697436,1.3766833583434828,1.1073832487263275
| 2,702
|
SLC superfamily of solute carriers
| 26
| 43
| 3.723614
| 0.000196
|
Q70HW3,Q8TB61,P53985,Q9UBX3,Q9BQT8,Q8NEW0,Q9H2V7,Q9UJS0,Q6NT16,Q96QD8,Q9NZJ7,Q9Y6M7,Q9H2D1,Q8IXU6,Q9H2H9,P41440,O43772,O43808,Q9BXP2,Q9Y619,O00400,O95202,P12236,Q99808,Q9Y6C9,P04920
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
1,258,271,144,146,152,153,420,37,559,427,304,53,61,198,457,83,337,609,226,352,363,614,633,509,502
|
352,83,337,921,363,1151,502,860,1057,889,978,614,457,271,2115,1159,1415,2657,37,642,1443,1,61,152,258,1503,559,633,146,609,1215,53,198,153,1629,896,427,144,420,1805,226,509,304
|
0.9478015835630615,2.3249577453845984,0.9747001337238531,0.13980900706892938,0.9207797152191141,-0.032915728384741015,0.6435101106197167,0.2013703373493341,0.030487470396744938,0.17067086843316673,0.09320779573109034,0.48524197874422104,0.7420485262435965,1.211424359795403,-0.6017771358819511,-0.032915728384741015,-0.19451519653859392,-1.6183674545716196,2.886090180376803,0.4560011507642696,-0.21092513401942328,4.343126506682812,2.4832547399290448,1.8349285964616746,1.275532592400303,-0.243884846085324,0.5720990698697436,0.4706398114973275,1.8696467178692489,0.4998078409542412,-0.0648782670729416,2.5967459172501477,1.4884520937953238,1.8349285964616746,-0.31037139890127774,0.17067086843316673,0.7976231963964028,1.8811746612706568,0.8114351982042777,-0.4115533912456994,1.3766833583434828,0.6435101106197167,1.1073832487263275
| 2,702
|
Inorganic molecular entity transmembrane transporter activity
| 33
| 75
| 3.722929
| 0.000197
|
O15439,P21796,P13073,P33527,Q9UBX3,Q96ES6,Q7KZN9,Q9C0H2,P45880,P05023,Q9Y5K8,Q96QD8,Q9Y487,Q9Y6M7,Q9Y277,O75964,P16615,P20674,P25705,Q9HD20,Q9H2H9,Q8N4V1,Q93050,P00403,Q9UDW1,P06576,O43681,O00400,O95202,P51790,P24539,Q13423,P04920
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
380,11,395,13,144,279,409,31,34,539,561,559,41,304,437,184,441,572,451,69,198,79,82,338,87,215,467,352,363,242,371,119,502
|
2055,352,380,467,1992,184,363,338,502,539,1252,860,215,1229,1323,1057,1230,1175,978,395,441,1022,572,1101,2406,11,941,371,451,2197,13,1614,1082,1876,34,2508,1969,242,1463,573,904,841,1563,1278,2115,1159,119,760,2657,409,79,1660,1475,2348,82,2427,279,559,669,764,609,31,1215,198,69,144,87,1217,1376,437,1805,41,561,2549,304
|
-0.566722147958878,0.9478015835630615,0.8936333486288025,0.7140629338857863,-0.5318785727630885,1.586065401491409,0.9207797152191141,0.9747001337238531,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,1.4017035243632918,-0.08092564237043719,-0.14556179771058245,0.030487470396744938,-0.08092564237043719,-0.04887504627384466,0.09320779573109034,0.8663612864956289,0.7699015142883784,0.061932036437784624,0.5432894598416556,-0.001127805810301048,-0.8901609796463711,3.541068752096914,0.12431661965225804,0.9072221686279333,0.7559915142019157,-0.6725321288961622,3.497184563628806,-0.31037139890127774,0.014701291299391921,-0.462815185693309,2.953902538225382,-1.0399582580540272,-0.514535240785251,1.3136668502909221,-0.22738159228350283,0.5432894598416556,0.1552603482535626,0.21665972726603153,-0.27703285170862874,-0.11315387381905866,-0.6017771358819511,-0.032915728384741015,1.9952458014491112,0.2925118928589216,-1.6183674545716196,0.8389623139505717,2.3463066784162883,-0.3271128392759249,-0.22738159228350283,-0.8167006259673601,2.3356417057869807,-0.9086735477231258,1.1985189212016558,0.5720990698697436,0.41186430071853863,0.2925118928589216,0.4998078409542412,2.9827338068802134,-0.0648782670729416,1.4884520937953238,2.4309512128450095,1.8811746612706568,2.303532579472338,-0.0648782670729416,-0.1618337970909173,0.7837786881907414,-0.4115533912456994,2.8371826720644844,0.5720990698697436,-1.1163480492502467,1.1073832487263275
| 2,702
|
Anion transmembrane transport
| 19
| 41
| 3.717765
| 0.000201
|
O15439,Q8TB61,P21796,P33527,P53985,Q9UBX3,Q9BQT8,Q9UHG3,P45880,Q9UJS0,Q9Y6M7,Q9Y277,Q9H2D1,P08183,P41440,O43808,Q9Y619,P51790,P04920
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
380,258,11,13,271,144,146,32,34,420,304,437,53,54,457,337,226,242,502
|
380,337,921,1637,1151,502,860,957,54,1057,978,614,11,13,457,34,1969,242,1463,271,2115,1159,1415,760,258,1475,1503,146,609,53,1629,896,538,144,32,420,437,1805,1545,226,304
|
0.8936333486288025,0.9747001337238531,0.13980900706892938,-0.3271128392759249,-0.032915728384741015,0.6435101106197167,0.2013703373493341,0.10878295888408213,2.5762697271805473,0.030487470396744938,0.09320779573109034,0.48524197874422104,3.541068752096914,3.497184563628806,0.7420485262435965,2.953902538225382,-0.514535240785251,1.3136668502909221,-0.22738159228350283,1.211424359795403,-0.6017771358819511,-0.032915728384741015,-0.19451519653859392,0.2925118928589216,1.275532592400303,-0.22738159228350283,-0.243884846085324,1.8696467178692489,0.4998078409542412,2.5967459172501477,-0.31037139890127774,0.17067086843316673,0.6007678594820233,1.8811746612706568,2.9731386427052393,0.8114351982042777,0.7837786881907414,-0.4115533912456994,-0.26043517265107846,1.3766833583434828,1.1073832487263275
| 2,702
|
Membrane lipid metabolic process
| 17
| 30
| 3.648349
| 0.000264
|
P07686,P50897,P07602,P17900,Q9NZJ7,Q8NBX0,Q06136,Q53H12,P06865,P06280,P04062,O95470,Q96G23,Q13510,P04066,P16278,O15269
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,3,4,162,427,75,204,237,92,112,188,275,120,26,439,93,415
|
415,1454,275,188,439,112,92,4,160,93,162,1555,1179,3,204,26,2671,237,75,643,659,120,1447,545,848,1172,1247,427,455,1484
|
0.8114351982042777,-0.22738159228350283,1.1985189212016558,1.549648138953408,0.7699015142883784,2.040271181152975,2.249632405350508,4.00405433878558,1.7531245573462935,2.2387939765464413,1.7295441678744543,-0.27703285170862874,-0.04887504627384466,4.03639791939681,1.463795947164361,3.0114283478612625,-1.7672271447732948,1.3263238911225568,2.367579939782527,0.4560011507642696,0.42661358757948437,1.9952458014491112,-0.21092513401942328,0.5864509778300103,0.21665972726603153,-0.032915728384741015,-0.08092564237043719,0.7976231963964028,0.7559915142019157,-0.22738159228350283
| 2,702
|
Organic anion transport
| 22
| 43
| 3.64409
| 0.000268
|
O15439,Q8TB61,P07602,P33527,P53985,Q9UBX3,Q9BQT8,Q9UJS0,Q96QD8,Q9NZJ7,Q9Y6M7,Q9H2D1,Q9H2H9,P41440,O43808,Q9Y619,O00400,P28288,P12236,Q99808,P14174,P04920
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
380,258,4,13,271,144,146,420,559,427,304,53,198,457,337,226,352,615,614,633,122,502
|
352,380,337,921,1637,1151,818,502,860,957,4,1057,889,978,614,122,1233,615,13,457,1969,271,1159,757,1415,642,1443,258,1475,1503,559,633,146,53,198,1629,896,427,144,420,1805,226,304
|
0.9478015835630615,0.8936333486288025,0.9747001337238531,0.13980900706892938,-0.3271128392759249,-0.032915728384741015,0.23190917857868676,0.6435101106197167,0.2013703373493341,0.10878295888408213,4.00405433878558,0.030487470396744938,0.17067086843316673,0.09320779573109034,0.48524197874422104,1.983936246561302,-0.08092564237043719,0.48524197874422104,3.497184563628806,0.7420485262435965,-0.514535240785251,1.211424359795403,-0.032915728384741015,0.2925118928589216,-0.19451519653859392,0.4560011507642696,-0.21092513401942328,1.275532592400303,-0.22738159228350283,-0.243884846085324,0.5720990698697436,0.4706398114973275,1.8696467178692489,2.5967459172501477,1.4884520937953238,-0.31037139890127774,0.17067086843316673,0.7976231963964028,1.8811746612706568,0.8114351982042777,-0.4115533912456994,1.3766833583434828,1.1073832487263275
| 2,702
|
Transmembrane transport
| 58
| 186
| 3.636512
| 0.000276
|
Q9NS69,Q70HW3,Q99595,Q8TB61,O15439,O95831,P21796,P13073,P33527,P53985,Q9UBX3,Q9BQT8,O75844,Q96PU5,Q96ES6,Q8NEW0,Q9H2V7,Q7KZN9,Q9C0H2,Q9UHG3,P45880,Q9UJS0,Q6NT16,Q15629,O75381,Q9BPX6,Q9Y6M7,Q9Y277,Q9H2D1,P08183,O75964,O75027,P16615,P04062,Q8IXU6,P31749,P25705,O43865,Q9HD20,Q9H2H9,Q8WTV0,Q8N4V1,O43772,O43808,P38435,P00403,Q9UDW1,P06576,O14925,Q9Y619,Q6P4A7,O00400,P23786,Q15388,O95202,P51790,P24539,Q13423
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,2,258,380,9,11,395,13,271,144,146,147,280,279,152,153,409,31,32,34,420,37,43,301,303,304,437,53,54,184,312,441,188,61,189,451,196,69,198,324,79,83,337,86,338,87,215,344,226,97,352,105,366,363,242,371,119
|
1319,1848,2055,352,1586,344,380,549,582,83,337,196,2057,312,2550,2531,301,1734,921,147,1637,1992,184,1225,363,1151,9,785,338,188,502,539,1252,860,957,215,1229,2327,1323,54,1057,1230,1175,2133,889,1350,2062,978,614,395,441,1874,2464,1022,572,1101,2406,2407,11,941,105,371,451,2408,2233,615,2507,1381,189,2197,1849,13,1614,1082,86,1876,457,1740,34,1356,2508,701,1969,983,755,242,1463,1681,271,1435,1821,573,904,2536,2345,841,1563,1158,865,513,1278,2115,2567,1159,1360,1746,988,1767,2220,119,1257,1028,2119,1335,366,43,1415,1655,2556,1043,760,37,642,1443,97,1,409,1110,61,2099,79,567,521,1660,152,258,2292,1475,324,1621,2348,2427,279,1093,1503,280,559,2659,2,1031,764,633,303,146,634,609,1784,31,1215,53,198,153,1629,1374,896,69,538,0,2167,144,87,674,2600,32,1217,420,1073,1376,437,1805,570,1545,783,226,2549,304
|
-0.14556179771058245,-0.4456774203599463,-0.566722147958878,0.9478015835630615,-0.29367816551779385,0.9612662003264605,0.8936333486288025,0.5720990698697436,0.5288313967073893,2.3249577453845984,0.9747001337238531,1.4884520937953238,-0.566722147958878,1.0678905729851498,-1.1356055001499545,-1.0971550435827746,1.1073832487263275,-0.377629316099032,0.13980900706892938,1.858096452664984,-0.3271128392759249,-0.5318785727630885,1.586065401491409,-0.08092564237043719,0.9207797152191141,-0.032915728384741015,3.601980510099323,0.2622891279230963,0.9747001337238531,1.549648138953408,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,0.10878295888408213,1.4017035243632918,-0.08092564237043719,-0.7984810752691569,-0.14556179771058245,2.5762697271805473,0.030487470396744938,-0.08092564237043719,-0.04887504627384466,-0.6193847456466299,0.17067086843316673,-0.1618337970909173,-0.566722147958878,0.09320779573109034,0.48524197874422104,0.8663612864956289,0.7699015142883784,-0.462815185693309,-0.9645715603540274,0.061932036437784624,0.5432894598416556,-0.001127805810301048,-0.8901609796463711,-0.8901609796463711,3.541068752096914,0.12431661965225804,2.096080199744481,0.9072221686279333,0.7559915142019157,-0.8901609796463711,-0.7082376548394596,0.48524197874422104,-1.0399582580540272,-0.17815150752877743,1.549648138953408,-0.6725321288961622,-0.4456774203599463,3.497184563628806,-0.31037139890127774,0.014701291299391921,2.303532579472338,-0.462815185693309,0.7420485262435965,-0.377629316099032,2.953902538225382,-0.1618337970909173,-1.0399582580540272,0.3673920803157548,-0.514535240785251,0.09320779573109034,0.2925118928589216,1.3136668502909221,-0.22738159228350283,-0.3439027766845685,1.211424359795403,-0.21092513401942328,-0.4285902586631195,0.5432894598416556,0.1552603482535626,-1.0971550435827746,-0.8167006259673601,0.21665972726603153,-0.27703285170862874,-0.032915728384741015,0.2013703373493341,0.6292972508241202,-0.11315387381905866,-0.6017771358819511,-1.174315546728808,-0.032915728384741015,-0.1618337970909173,-0.377629316099032,0.09320779573109034,-0.3945665116133365,-0.6903572636353332,1.9952458014491112,-0.09701742595051951,0.061932036437784624,-0.6017771358819511,-0.14556179771058245,0.9207797152191141,2.7878758792557337,-0.19451519653859392,-0.3271128392759249,-1.1356055001499545,0.04623097246479662,0.2925118928589216,2.886090180376803,0.4560011507642696,-0.21092513401942328,2.217058138603211,4.343126506682812,0.8389623139505717,-0.001127805810301048,2.4832547399290448,-0.5842230489234069,2.3463066784162883,0.5577119571515898,0.6150498919054735,-0.3271128392759249,1.8349285964616746,1.275532592400303,-0.7441656379825385,-0.22738159228350283,1.0281319155612654,-0.31037139890127774,-0.8167006259673601,-0.9086735477231258,1.1985189212016558,0.014701291299391921,-0.243884846085324,1.1985189212016558,0.5720990698697436,-1.6393962657387167,4.084595663215114,0.061932036437784624,0.2925118928589216,0.4706398114973275,1.1073832487263275,1.8696467178692489,0.4706398114973275,0.4998078409542412,-0.3945665116133365,2.9827338068802134,-0.0648782670729416,2.5967459172501477,1.4884520937953238,1.8349285964616746,-0.31037139890127774,-0.1618337970909173,0.17067086843316673,2.4309512128450095,0.6007678594820233,4.48719359410752,-0.6370462182791121,1.8811746612706568,2.303532579472338,0.41186430071853863,-1.2722506277254433,2.9731386427052393,-0.0648782670729416,0.8114351982042777,0.030487470396744938,-0.1618337970909173,0.7837786881907414,-0.4115533912456994,0.5577119571515898,-0.26043517265107846,0.2774200528143013,1.3766833583434828,-1.1163480492502467,1.1073832487263275
| 2,702
|
Cognitive impairment
| 52
| 141
| 3.63226
| 0.000281
|
P50897,P07602,Q99720,Q9UBB4,O95831,Q10713,Q9Y2R0,Q9BQE5,O95470,Q13510,Q14108,Q9UEY8,P40855,P07686,P17900,Q9UJS0,Q9NZJ7,Q9Y487,O75381,Q4G176,Q5JTZ9,P54802,P20700,P07196,Q9NQZ5,P04062,P31749,O15118,P04350,O60313,P35637,O75503,P21964,Q9BVA1,Q13217,P00403,Q8N0X7,O43681,P06865,P16278,Q6PI48,Q9Y619,Q6DKK2,O15020,P22626,Q9Y5P6,P06280,Q9Y263,P61916,Q9NZ08,Q03164,Q6Y7W6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
3,4,5,525,9,397,14,16,275,26,29,546,288,160,162,420,427,41,301,432,433,50,309,185,60,188,189,63,449,326,203,206,207,466,463,338,217,467,92,93,479,226,100,481,354,497,112,508,248,250,123,516
|
1099,481,63,467,326,1674,1321,1608,301,206,592,275,9,785,338,188,2257,449,1198,112,92,185,4,160,2275,922,2194,1154,889,978,93,162,1021,1176,309,2407,1233,1431,207,2505,354,2112,2298,1903,189,203,1082,1876,288,604,1712,1740,616,879,2279,1182,1648,1969,983,3,2583,2281,1593,984,50,1411,2094,658,2217,1563,248,1131,2035,565,1468,1882,123,1908,2159,397,2037,2498,712,1203,463,26,29,541,2307,1390,1087,990,1064,2398,432,433,1657,726,100,2359,1690,479,516,2413,2639,217,1500,727,928,2468,2014,706,1696,780,805,2659,1863,2609,5,16,1838,466,1603,60,795,1668,250,427,525,1804,546,1757,420,1955,612,508,14,41,783,497,226
|
-0.001127805810301048,0.6859434192423728,2.472830381816948,0.7140629338857863,1.014819277244463,-0.3439027766845685,-0.14556179771058245,-0.31037139890127774,1.1073832487263275,1.4514293500729303,0.5143375851029162,1.1985189212016558,3.601980510099323,0.2622891279230963,0.9747001337238531,1.549648138953408,-0.7261736594651729,0.7559915142019157,-0.0648782670729416,2.040271181152975,2.249632405350508,1.586065401491409,4.00405433878558,1.7531245573462935,-0.7441656379825385,0.13980900706892938,-0.6725321288961622,-0.032915728384741015,0.17067086843316673,0.09320779573109034,2.2387939765464413,1.7295441678744543,0.061932036437784624,-0.04887504627384466,1.0810841689575286,-0.8901609796463711,-0.08092564237043719,-0.21092513401942328,1.4390369219353498,-1.0399582580540272,0.9478015835630615,-0.6017771358819511,-0.7622139544215649,-0.4800038669191164,1.549648138953408,1.463795947164361,0.014701291299391921,-0.462815185693309,1.1726232359899564,0.4998078409542412,-0.36074150382824394,-0.377629316099032,0.48524197874422104,0.18604079096340007,-0.7441656379825385,-0.04887504627384466,-0.3271128392759249,-0.514535240785251,0.09320779573109034,4.03639791939681,-1.2132888500172512,-0.7441656379825385,-0.29367816551779385,0.09320779573109034,2.6577600342457113,-0.19451519653859392,-0.5842230489234069,0.42661358757948437,-0.6903572636353332,-0.27703285170862874,1.3009827009421377,-0.017000063987738737,-0.5492740993843713,0.5577119571515898,-0.22738159228350283,-0.462815185693309,1.983936246561302,-0.4800038669191164,-0.6370462182791121,0.8663612864956289,-0.5492740993843713,-1.0210186165202892,0.35249256146592,-0.0648782670729416,0.7280723875131836,3.0114283478612625,3.0018786097104724,0.5864509778300103,-0.7622139544215649,-0.17815150752877743,0.014701291299391921,0.09320779573109034,0.030487470396744938,-0.8717077957387307,0.7837786881907414,0.7837786881907414,-0.3271128392759249,0.3375549865593367,2.1733484536781895,-0.8349780072652183,-0.3439027766845685,0.700019999999374,0.6292972508241202,-0.8901609796463711,-1.4937984028764713,1.4017035243632918,-0.243884846085324,0.3375549865593367,0.13980900706892938,-0.9645715603540274,-0.5318785727630885,0.3673920803157548,-0.3439027766845685,0.2774200528143013,0.24711890736266962,-1.6393962657387167,-0.4456774203599463,-1.311898640240956,4.00405433878558,3.4352105279543297,-0.4285902586631195,0.7280723875131836,-0.29367816551779385,2.5040493921299296,0.2622891279230963,-0.3271128392759249,1.3009827009421377,0.7976231963964028,0.6150498919054735,-0.4115533912456994,0.5864509778300103,-0.377629316099032,0.8114351982042777,-0.4972437792285436,0.4998078409542412,0.6435101106197167,3.497184563628806,2.8371826720644844,0.2774200528143013,0.6718330237408522,1.3766833583434828
| 2,702
|
Lipid localization
| 28
| 64
| 3.623585
| 0.000291
|
O15439,P07602,Q99720,Q9BUR5,Q9H6V9,P33527,Q9BQE5,P35790,Q9H2V7,Q14108,P07686,P30536,P17900,Q9NZJ7,Q6P1A2,P08183,Q14534,P04062,P31749,O15118,Q8WTV0,O43772,O43808,Q9H4L5,P23786,O15260,P61916,P14174
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
380,4,5,393,8,13,16,148,153,29,160,289,162,427,424,54,311,188,189,63,324,83,337,358,105,109,248,122
|
636,2701,63,109,380,83,337,1034,2389,1427,438,2432,188,818,1229,4,160,2275,54,889,122,162,1555,1353,105,615,1711,289,189,1849,13,148,1765,248,1564,2567,1746,29,311,760,1281,424,1443,713,567,2482,324,2047,5,16,1372,393,1698,1784,2484,153,358,8,427,1484,1290,1073,1926,1515
|
0.4560011507642696,-7.609059479882954,2.472830381816948,2.0626573264796644,0.8936333486288025,2.3249577453845984,0.9747001337238531,0.04623097246479662,-0.8717077957387307,-0.21092513401942328,0.7699015142883784,-0.9272458982666049,1.549648138953408,0.23190917857868676,-0.08092564237043719,4.00405433878558,1.7531245573462935,-0.7441656379825385,2.5762697271805473,0.17067086843316673,1.983936246561302,1.7295441678744543,-0.27703285170862874,-0.1618337970909173,2.096080199744481,0.48524197874422104,-0.36074150382824394,1.1596327314267856,1.549648138953408,-0.4456774203599463,3.497184563628806,1.858096452664984,-0.3945665116133365,1.3009827009421377,-0.27703285170862874,-1.174315546728808,-0.377629316099032,3.0018786097104724,1.0810841689575286,0.2925118928589216,-0.11315387381905866,0.7976231963964028,-0.21092513401942328,0.35249256146592,0.5577119571515898,-0.983325689072196,1.0281319155612654,-0.5492740993843713,4.00405433878558,3.4352105279543297,-0.1618337970909173,0.8800131050184969,-0.3439027766845685,-0.3945665116133365,-0.983325689072196,1.8349285964616746,0.9478015835630615,3.627900422577668,0.7976231963964028,-0.22738159228350283,-0.11315387381905866,0.030487470396744938,-0.4800038669191164,-0.243884846085324
| 2,702
|
Nuclear outer membrane endoplasmic reticulum membrane network
| 95
| 262
| 3.553878
| 0.00038
|
Q8NHH9,Q99720,P84095,Q9Y4P3,Q96JJ7,P24390,Q9BQE5,Q8IV08,Q53GQ0,P61970,Q13190,Q99735,Q14108,Q6NUQ1,P30519,Q8N0U8,Q15629,Q5BJF2,Q10472,P43307,P46977,Q8NB49,Q9P2W9,Q9Y282,Q16850,Q9HD20,P07099,Q8TCT9,Q8N4V1,P38435,P52292,Q86XL3,Q70UQ0,O15260,Q8TCT8,Q96G23,Q9Y3B3,Q9Y5M8,O95197,O75844,P37268,O00264,P67812,Q15392,Q96PC5,Q14739,Q07065,O43852,Q9H3N1,O43865,O60725,Q9UBU6,Q06136,P50402,Q9NZ08,Q8TB61,Q96HY6,P51648,O95470,Q6NUM9,Q9BRR6,Q9NQC3,Q14534,Q8TD16,Q9BV10,P35613,P09601,Q13555,Q9UBM7,Q9H4L5,O00400,Q15800,Q15363,Q9UBV2,O14735,Q9BUR5,P16435,O95070,P48449,Q8NF37,Q9BUN8,O15269,Q9P2E9,P10321,Q8N2K0,Q6P1A2,Q96A33,Q96KC8,P16615,O95674,A1L0T0,Q9P035,P51572,Q15904,Q8WXH0
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
518,5,514,528,523,15,16,19,535,23,532,545,29,542,35,40,43,47,554,51,563,567,59,62,65,69,70,77,79,86,90,102,103,109,118,120,130,136,142,147,154,159,165,166,172,175,179,190,191,196,201,205,204,233,250,258,272,277,275,283,298,308,311,313,320,328,334,346,359,358,352,367,372,384,379,393,388,386,396,405,413,415,428,423,425,424,442,445,441,438,448,455,469,488,506
|
636,448,159,352,1099,2463,637,973,710,638,379,1488,1018,1077,1759,109,415,1454,1489,1122,190,196,1732,656,201,2326,1733,887,147,1637,1174,876,1250,798,386,142,1735,275,2389,901,1427,438,799,2431,2487,859,1228,1080,2644,70,2313,1380,334,423,890,388,441,819,979,1555,2505,15,1492,1998,1408,2451,1302,35,1381,1326,1849,1234,328,154,86,2000,604,1712,51,563,1460,396,982,1765,1327,1878,701,1969,594,233,1201,469,277,90,2156,2376,2178,2094,985,649,2536,1006,2283,2137,823,1905,2420,1563,1822,1823,23,1939,865,2422,2238,165,514,1528,2691,1026,204,179,1062,554,1616,1133,1084,532,346,1617,29,1440,311,175,724,927,1442,372,166,2138,1064,43,2043,367,488,65,867,535,47,869,695,2008,1750,963,283,542,802,424,1443,1691,1164,103,2494,684,667,620,102,870,19,1110,40,425,79,1500,1419,1862,567,727,405,715,518,1211,258,2011,2292,118,77,313,1475,1091,2012,506,716,659,1397,777,1342,442,1369,965,120,1093,272,523,445,172,1447,669,5,545,1914,16,298,849,1372,413,393,320,752,1784,1215,191,358,949,1051,1245,69,1666,1095,308,611,1033,875,1172,1247,250,455,969,1484,428,59,1867,359,205,384,674,568,2570,1376,1345,62,935,812,1119,130,2502,528,1634,136,1807,936,1515
|
0.4560011507642696,0.7559915142019157,1.7531245573462935,0.9478015835630615,-0.001127805810301048,-0.9645715603540274,0.4560011507642696,0.09320779573109034,0.35249256146592,0.4560011507642696,0.8936333486288025,-0.243884846085324,0.061932036437784624,0.014701291299391921,-0.3945665116133365,2.0626573264796644,0.8114351982042777,-0.22738159228350283,-0.243884846085324,-0.017000063987738737,1.5374592754176952,1.4884520937953238,-0.377629316099032,0.42661358757948437,1.4761368247888418,-0.7984810752691569,-0.377629316099032,0.17067086843316673,1.858096452664984,-0.3271128392759249,-0.04887504627384466,0.18604079096340007,-0.09701742595051951,0.24711890736266962,0.8800131050184969,1.8811746612706568,-0.377629316099032,1.1985189212016558,-0.8717077957387307,0.1552603482535626,-0.21092513401942328,0.7699015142883784,0.24711890736266962,-0.9272458982666049,-1.0021412347204408,0.2013703373493341,-0.08092564237043719,0.014701291299391921,-1.5350197765489455,2.420435656490256,-0.7803189764195482,-0.17815150752877743,0.9881035286247505,0.7976231963964028,0.17067086843316673,0.8800131050184969,0.7699015142883784,0.23190917857868676,0.09320779573109034,-0.27703285170862874,-1.0399582580540272,3.4883696583674233,-0.243884846085324,-0.5318785727630885,-0.19451519653859392,-0.9458784336451688,-0.12933524422973913,2.915245805395765,-0.17815150752877743,-0.14556179771058245,-0.4456774203599463,-0.08092564237043719,1.0014765288625636,1.8233108238857811,2.303532579472338,-0.5318785727630885,0.4998078409542412,-0.36074150382824394,2.637490586614291,0.5577119571515898,-0.22738159228350283,0.8663612864956289,0.09320779573109034,-0.3945665116133365,-0.14556179771058245,-0.462815185693309,0.3673920803157548,-0.514535240785251,0.5143375851029162,1.338953943492325,-0.0648782670729416,0.7140629338857863,1.1985189212016558,2.282030613119506,-0.6370462182791121,-0.8533136017184143,-0.6547618971329058,-0.5842230489234069,0.09320779573109034,0.4413258066063131,-1.0971550435827746,0.07759089922445578,-0.7441656379825385,-0.6193847456466299,0.23190917857868676,-0.4800038669191164,-0.9086735477231258,-0.27703285170862874,-0.4285902586631195,-0.4285902586631195,3.106106395795426,-0.4972437792285436,0.2013703373493341,-0.9086735477231258,-0.7082376548394596,1.717718863168589,0.6292972508241202,-0.26043517265107846,-3.291501686426648,0.061932036437784624,1.463795947164361,1.6222608747574856,0.030487470396744938,0.5720990698697436,-0.31037139890127774,-0.017000063987738737,0.014701291299391921,0.6007678594820233,0.9612662003264605,-0.31037139890127774,3.0018786097104724,-0.21092513401942328,1.0810841689575286,1.658237345935038,0.3375549865593367,0.13980900706892938,-0.21092513401942328,0.9072221686279333,1.705870022831379,-0.6193847456466299,0.030487470396744938,2.7878758792557337,-0.5492740993843713,0.9207797152191141,0.6718330237408522,2.45192727608413,0.2013703373493341,0.6007678594820233,2.7381629713773825,0.2013703373493341,0.382253743928895,-0.5318785727630885,-0.377629316099032,0.10878295888408213,1.1855852561088989,0.5864509778300103,0.24711890736266962,0.7976231963964028,-0.21092513401942328,-0.3439027766845685,-0.032915728384741015,2.15137339820128,-1.0021412347204408,0.39707775152061925,0.41186430071853863,0.48524197874422104,2.1623710072700724,0.2013703373493341,3.2085718590601604,-0.001127805810301048,2.8371826720644844,0.7976231963964028,2.3463066784162883,-0.243884846085324,-0.19451519653859392,-0.4456774203599463,0.5577119571515898,0.3375549865593367,0.852677740649789,0.35249256146592,0.6292972508241202,-0.0648782670729416,1.275532592400303,-0.5318785727630885,-0.7441656379825385,2.0065339889232616,2.3569527332268905,1.0678905729851498,-0.22738159228350283,0.014701291299391921,-0.5318785727630885,0.6435101106197167,0.35249256146592,0.42661358757948437,-0.17815150752877743,0.2774200528143013,-0.14556179771058245,0.7699015142883784,-0.1618337970909173,0.10878295888408213,1.9952458014491112,0.014701291299391921,1.211424359795403,0.6150498919054735,0.7699015142883784,1.6701813099617207,-0.21092513401942328,0.41186430071853863,4.00405433878558,0.5864509778300103,-0.4800038669191164,3.4352105279543297,1.1204890033550043,0.21665972726603153,-0.1618337970909173,0.8252148517366122,0.8800131050184969,1.0414145845970093,0.30756485716682186,-0.3945665116133365,-0.0648782670729416,1.5374592754176952,0.9478015835630615,0.12431661965225804,0.04623097246479662,-0.08092564237043719,2.4309512128450095,-0.3271128392759249,0.014701291299391921,1.0942483489073807,0.4998078409542412,0.061932036437784624,0.2013703373493341,-0.032915728384741015,-0.08092564237043719,1.3009827009421377,0.7559915142019157,0.10878295888408213,-0.22738159228350283,0.7976231963964028,2.5351071762344404,-0.4456774203599463,0.9478015835630615,1.463795947164361,0.8936333486288025,0.41186430071853863,0.5577119571515898,-1.174315546728808,-0.1618337970909173,-0.14556179771058245,2.4832547399290448,0.13980900706892938,0.24711890736266962,-0.001127805810301048,1.9612526973306057,-1.0210186165202892,0.6150498919054735,-0.31037139890127774,1.9270649969621256,-0.4115533912456994,0.13980900706892938,-0.243884846085324
| 2,702
|
Transporter
| 69
| 178
| 3.552734
| 0.000381
|
O15439,Q70HW3,Q8TB61,Q8N2H4,P37198,P11279,P33527,P24390,Q9BQE5,Q9UBX3,Q9BQT8,P53985,Q96ES6,Q8NEW0,Q13190,Q9H2V7,Q9HD45,P17900,P05023,Q6NT16,Q9Y5K8,Q8NFH4,Q96QD8,Q9Y487,Q7Z3B4,Q9UJS0,Q9NZJ7,Q9Y6M7,Q92973,Q9H2D1,P08183,Q8NB49,O75027,Q12769,Q9P2W9,P16615,Q8IXU6,P25705,P56134,Q9H2H9,P41440,O43760,Q93050,O43772,Q15070,O43808,P51572,P06576,P52292,O15400,Q9BXP2,Q9Y619,Q9P253,O00400,O95721,O95249,Q15388,Q8N1F7,O95202,P28288,P12236,Q8TEX9,P24539,Q99808,Q15363,Q9Y6C9,P04920,Q6NUK1,Q9Y3B3
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
380,1,258,132,133,387,13,15,16,144,146,271,279,152,532,153,285,162,539,37,561,291,559,41,557,420,427,304,434,53,54,567,312,566,59,441,61,451,573,198,457,81,82,83,85,337,469,215,90,475,609,226,486,352,353,364,366,238,363,615,614,492,371,633,372,509,502,642,130
|
2352,1848,2148,352,2310,637,814,710,2516,475,380,81,83,337,1034,2087,689,1490,312,2430,921,1992,798,363,364,1735,2389,901,1151,353,785,502,539,1252,860,215,54,1057,976,977,889,387,978,614,441,162,1022,1101,2406,941,15,371,451,615,1003,13,1234,1614,133,1876,457,1460,1765,1327,701,983,469,90,1235,2156,2376,756,271,2178,787,1821,1493,985,573,904,658,841,1563,1823,1940,1278,2115,2035,961,1159,1494,827,566,788,1133,532,1716,880,1162,1010,85,1335,372,366,1415,2657,37,642,1443,1,557,684,713,61,1946,238,132,567,152,291,1913,258,1091,492,1501,1394,2012,895,2604,434,82,804,279,1503,559,780,1834,707,848,633,16,146,1477,752,609,1448,1215,1578,53,198,153,1629,896,285,427,2051,1484,486,59,1867,1581,144,1217,2485,420,1001,675,951,1805,1119,130,41,561,1634,226,936,509,304
|
-0.8349780072652183,-0.4456774203599463,-0.6370462182791121,0.9478015835630615,-0.7803189764195482,0.4560011507642696,0.23190917857868676,0.35249256146592,-1.0589605873257606,0.700019999999374,0.8936333486288025,2.3356417057869807,2.3249577453845984,0.9747001337238531,0.04623097246479662,-0.5842230489234069,0.382253743928895,-0.243884846085324,1.0678905729851498,-0.9272458982666049,0.13980900706892938,-0.5318785727630885,0.24711890736266962,0.9207797152191141,0.9207797152191141,-0.377629316099032,-0.8717077957387307,0.1552603482535626,-0.032915728384741015,0.9478015835630615,0.2622891279230963,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,1.4017035243632918,2.5762697271805473,0.030487470396744938,0.09320779573109034,0.09320779573109034,0.17067086843316673,0.8800131050184969,0.09320779573109034,0.48524197874422104,0.7699015142883784,1.7295441678744543,0.061932036437784624,-0.001127805810301048,-0.8901609796463711,0.12431661965225804,3.4883696583674233,0.9072221686279333,0.7559915142019157,0.48524197874422104,0.07759089922445578,3.497184563628806,-0.08092564237043719,-0.31037139890127774,1.9384826617323367,-0.462815185693309,0.7420485262435965,-0.22738159228350283,-0.3945665116133365,-0.14556179771058245,0.3673920803157548,0.09320779573109034,0.7140629338857863,2.282030613119506,-0.08092564237043719,-0.6370462182791121,-0.8533136017184143,0.2925118928589216,1.211424359795403,-0.6547618971329058,0.2622891279230963,-0.4285902586631195,-0.243884846085324,0.09320779573109034,0.5432894598416556,0.1552603482535626,0.42661358757948437,0.21665972726603153,-0.27703285170862874,-0.4285902586631195,-0.4972437792285436,-0.11315387381905866,-0.6017771358819511,-0.5492740993843713,0.10878295888408213,-0.032915728384741015,-0.243884846085324,0.23190917857868676,0.5577119571515898,0.2622891279230963,-0.017000063987738737,0.6007678594820233,-0.36074150382824394,0.18604079096340007,-0.032915728384741015,0.07759089922445578,2.314254726861213,-0.14556179771058245,0.9072221686279333,0.9207797152191141,-0.19451519653859392,-1.6183674545716196,2.886090180376803,0.4560011507642696,-0.21092513401942328,4.343126506682812,0.5720990698697436,0.39707775152061925,0.35249256146592,2.4832547399290448,-0.4972437792285436,1.3263238911225568,1.94987853311504,0.5577119571515898,1.8349285964616746,1.1596327314267856,-0.4800038669191164,1.275532592400303,0.014701291299391921,0.6718330237408522,-0.243884846085324,-0.17815150752877743,-0.5318785727630885,0.17067086843316673,-1.2920402919692853,0.7837786881907414,2.3356417057869807,0.24711890736266962,1.1985189212016558,-0.243884846085324,0.5720990698697436,0.2774200528143013,-0.4285902586631195,0.3673920803157548,0.21665972726603153,0.4706398114973275,3.4352105279543297,1.8696467178692489,-0.22738159228350283,0.30756485716682186,0.4998078409542412,-0.21092513401942328,-0.0648782670729416,-0.27703285170862874,2.5967459172501477,1.4884520937953238,1.8349285964616746,-0.31037139890127774,0.17067086843316673,1.1855852561088989,0.7976231963964028,-0.5492740993843713,-0.22738159228350283,0.6859434192423728,2.5351071762344404,-0.4456774203599463,-0.27703285170862874,1.8811746612706568,-0.0648782670729416,-0.983325689072196,0.8114351982042777,0.09320779573109034,0.41186430071853863,0.12431661965225804,-0.4115533912456994,-0.001127805810301048,1.9612526973306057,2.8371826720644844,0.5720990698697436,-0.31037139890127774,1.3766833583434828,0.13980900706892938,0.6435101106197167,1.1073832487263275
| 2,702
|
Intrinsic component of endoplasmic reticulum membrane
| 22
| 45
| 3.529387
| 0.000417
|
Q8TB61,A0FGR8,P57088,Q9Y4P3,O75844,O95470,Q9BUN8,Q9P2E9,P10321,Q15629,Q9NQC3,Q96A33,Q9UKV5,Q9Y282,Q9P035,Q8TCT9,Q8N4V1,P51572,Q9UBM7,Q86UP2,Q86XL3,Q8TCT8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
258,636,649,528,147,275,413,428,423,43,308,442,568,62,455,77,79,469,359,620,102,118
|
636,973,1122,147,1174,275,2487,423,1998,1408,1302,469,649,1563,1084,1440,927,43,869,963,620,102,79,1419,258,118,77,659,442,1447,1372,413,1245,1095,308,1247,455,969,428,359,568,1376,62,528,1515
|
0.4560011507642696,0.09320779573109034,-0.017000063987738737,1.858096452664984,-0.04887504627384466,1.1985189212016558,-1.0021412347204408,0.7976231963964028,-0.5318785727630885,-0.19451519653859392,-0.12933524422973913,0.7140629338857863,0.4413258066063131,-0.27703285170862874,0.014701291299391921,-0.21092513401942328,0.13980900706892938,2.7878758792557337,0.2013703373493341,0.10878295888408213,0.48524197874422104,2.1623710072700724,2.3463066784162883,-0.19451519653859392,1.275532592400303,2.0065339889232616,2.3569527332268905,0.42661358757948437,0.7699015142883784,-0.21092513401942328,-0.1618337970909173,0.8252148517366122,-0.08092564237043719,0.014701291299391921,1.0942483489073807,-0.08092564237043719,0.7559915142019157,0.10878295888408213,0.7976231963964028,0.9478015835630615,0.5577119571515898,-0.1618337970909173,2.4832547399290448,0.6150498919054735,-0.243884846085324
| 2,702
|
Mitochondrial transport
| 28
| 73
| 3.509503
| 0.000449
|
Q9NS69,Q99595,O95831,O14737,Q10713,Q9Y5J9,Q9UBX3,P55786,P30536,P45880,Q9UJS0,Q5JRX3,O75964,Q9Y5J7,P25705,Q8N4H5,Q96EK5,O43772,Q15070,O14925,P06576,P51572,Q8TB36,P23786,Q53H12,Q15388,Q9P0J0,P24539
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,2,9,265,397,400,144,28,289,34,420,295,184,317,451,72,330,83,85,344,215,469,484,105,237,366,375,371
|
1219,265,344,549,83,499,1734,1992,184,1225,1296,9,785,1198,860,215,1551,1710,2133,978,2560,105,371,451,2507,1004,289,2372,1614,2300,34,2508,1327,1969,469,1681,28,573,904,2394,397,85,366,2556,1043,237,295,642,2164,995,1981,72,484,1621,330,780,805,2,764,634,1139,1374,0,375,2364,144,420,1073,1758,569,663,317,400
|
-0.08092564237043719,1.237151067189716,0.9612662003264605,0.5720990698697436,2.3249577453845984,0.6576886443457405,-0.377629316099032,-0.5318785727630885,1.586065401491409,-0.08092564237043719,-0.12933524422973913,3.601980510099323,0.2622891279230963,-0.0648782670729416,0.2013703373493341,1.4017035243632918,-0.27703285170862874,-0.36074150382824394,-0.6193847456466299,0.09320779573109034,-1.1549278473496636,2.096080199744481,0.9072221686279333,0.7559915142019157,-1.0399582580540272,0.07759089922445578,1.1596327314267856,-0.8533136017184143,-0.31037139890127774,-0.7622139544215649,2.953902538225382,-1.0399582580540272,-0.14556179771058245,-0.514535240785251,0.7140629338857863,-0.3439027766845685,3.0018786097104724,0.5432894598416556,0.1552603482535626,-0.8717077957387307,0.8663612864956289,2.314254726861213,0.9207797152191141,-1.1356055001499545,0.04623097246479662,1.3263238911225568,1.1466136121023172,0.4560011507642696,-0.6370462182791121,0.09320779573109034,-0.514535240785251,2.420435656490256,0.6859434192423728,-0.31037139890127774,1.0014765288625636,0.2774200528143013,0.24711890736266962,4.084595663215114,0.2925118928589216,0.4706398114973275,-0.017000063987738737,-0.1618337970909173,4.48719359410752,0.9072221686279333,-0.8349780072652183,1.8811746612706568,0.8114351982042777,0.030487470396744938,-0.377629316099032,0.5577119571515898,0.42661358757948437,1.0546674241385827,0.8663612864956289
| 2,702
|
Lipid binding
| 31
| 122
| 3.491603
| 0.00048
|
O94788,P50897,P07602,P37198,P21796,Q9H0H5,Q9BQE5,O15254,O14773,Q9Y5X3,Q14108,O00264,O15173,P45880,P30536,P11717,Q15067,A6NIH7,P04062,P31749,Q9NQZ5,O15118,Q8WTV0,O60313,Q96L92,Q13432,P38435,Q9H4L5,P28070,P61916,O14735
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
127,3,4,133,11,270,16,21,150,414,29,159,33,34,289,417,297,46,188,189,60,63,324,326,331,214,86,358,355,248,379
|
636,46,159,1958,1099,2190,637,379,150,699,481,63,33,21,2311,501,1550,326,645,956,689,1267,887,127,1250,2212,188,818,539,1229,4,1898,1323,2111,1899,2133,1589,1519,2337,417,2580,979,1233,11,1555,1353,2065,355,2233,1711,1325,289,189,1559,133,86,34,2343,1272,1765,3,630,2683,2330,822,1435,2094,1744,986,248,1564,565,2567,1495,828,214,1716,1362,880,29,1206,926,297,830,2322,1046,643,739,324,929,659,833,2184,1370,1798,331,2047,1031,1601,1781,1625,16,1372,1698,1784,270,358,507,60,427,2470,1073,1868,1098,810,675,569,1016,1806,662,1075,414
|
0.4560011507642696,2.7381629713773825,1.7531245573462935,-0.514535240785251,-0.001127805810301048,-0.6725321288961622,0.4560011507642696,0.8936333486288025,1.8349285964616746,0.3673920803157548,0.6859434192423728,2.472830381816948,2.953902538225382,3.162211161281815,-0.7803189764195482,0.6435101106197167,-0.27703285170862874,1.014819277244463,0.4413258066063131,0.10878295888408213,0.382253743928895,-0.11315387381905866,0.17067086843316673,1.9612526973306057,-0.09701742595051951,-0.6903572636353332,1.549648138953408,0.23190917857868676,0.5864509778300103,-0.08092564237043719,4.00405433878558,-0.4800038669191164,-0.14556179771058245,-0.6017771358819511,-0.4800038669191164,-0.6193847456466299,-0.29367816551779385,-0.26043517265107846,-0.8167006259673601,0.8114351982042777,-1.2132888500172512,0.09320779573109034,-0.08092564237043719,3.541068752096914,-0.27703285170862874,-0.1618337970909173,-0.566722147958878,0.9478015835630615,-0.7082376548394596,-0.36074150382824394,-0.14556179771058245,1.1596327314267856,1.549648138953408,-0.27703285170862874,1.9384826617323367,2.303532579472338,2.953902538225382,-0.8167006259673601,-0.11315387381905866,-0.3945665116133365,4.03639791939681,0.4706398114973275,-2.1921262614398054,-0.7984810752691569,0.23190917857868676,-0.21092513401942328,-0.5842230489234069,-0.377629316099032,0.09320779573109034,1.3009827009421377,-0.27703285170862874,0.5577119571515898,-1.174315546728808,-0.243884846085324,0.23190917857868676,1.4141741225146764,-0.36074150382824394,-0.1618337970909173,0.18604079096340007,3.0018786097104724,-0.0648782670729416,0.13980900706892938,1.1204890033550043,0.23190917857868676,-0.7803189764195482,0.04623097246479662,0.4560011507642696,0.32257915315367963,1.0281319155612654,0.13980900706892938,0.42661358757948437,0.23190917857868676,-0.6547618971329058,-0.1618337970909173,-0.4115533912456994,1.0014765288625636,-0.5492740993843713,0.061932036437784624,-0.29367816551779385,-0.3945665116133365,-0.31037139890127774,3.4352105279543297,-0.1618337970909173,-0.3439027766845685,-0.3945665116133365,1.224301699534718,0.9478015835630615,0.6435101106197167,2.5040493921299296,0.7976231963964028,-0.9645715603540274,0.030487470396744938,-0.4456774203599463,0.014701291299391921,0.24711890736266962,0.41186430071853863,0.5577119571515898,0.07759089922445578,-0.4115533912456994,0.42661358757948437,0.030487470396744938,0.8252148517366122
| 2,702
|
Sphingolipid metabolic process
| 15
| 25
| 3.487307
| 0.000488
|
P07686,P50897,P07602,P17900,Q9NZJ7,Q06136,Q53H12,P06865,P06280,O95470,Q96G23,Q13510,P04062,P16278,O15269
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,3,4,162,427,204,237,92,112,275,120,26,188,93,415
|
415,1454,275,188,112,92,4,160,93,162,1555,1179,3,204,26,2671,237,643,120,848,1172,1247,427,455,1484
|
0.8114351982042777,-0.22738159228350283,1.1985189212016558,1.549648138953408,2.040271181152975,2.249632405350508,4.00405433878558,1.7531245573462935,2.2387939765464413,1.7295441678744543,-0.27703285170862874,-0.04887504627384466,4.03639791939681,1.463795947164361,3.0114283478612625,-1.7672271447732948,1.3263238911225568,0.4560011507642696,1.9952458014491112,0.21665972726603153,-0.032915728384741015,-0.08092564237043719,0.7976231963964028,0.7559915142019157,-0.22738159228350283
| 2,702
|
Endoplasmic reticulum
| 134
| 409
| 3.484205
| 0.000494
|
Q92542,Q8NHH9,Q99720,Q9H6V9,P84095,Q9Y4P3,Q96JJ7,P24390,Q9BQE5,Q8IV08,Q53GQ0,Q13190,Q13510,Q99735,Q14108,O15173,Q6NUQ1,P30519,P05023,P10619,Q9H1A3,Q8N0U8,Q8IY95,Q15629,Q5BJF2,Q10472,O75718,P43307,Q14257,P46977,Q8NB49,Q9P2W9,Q9Y282,O15118,Q16850,Q9HD20,P07099,Q8TCT9,Q8N4V1,P38435,P52292,Q9NWM8,Q86XL3,Q70UQ0,O15260,Q8TCT8,Q96G23,Q9Y3B3,O00584,Q9UMX5,P80303,Q9Y5M8,O95197,O75844,P37268,O00264,P13674,P67812,Q15392,Q96PC5,Q14739,Q07065,P04062,O43852,Q9H3N1,Q96LJ7,Q92791,O15460,O43865,O60725,Q9UBU6,Q06136,O75503,O43390,Q9UQB8,Q32P28,O60506,P50402,Q02818,Q9H2J4,P61916,Q9NZ08,Q13641,Q8TB61,P00367,Q96HY6,P51648,O95470,Q6NUM9,P30536,Q9BRR6,Q9BTY2,Q9NQC3,Q14534,Q9H8H3,Q9BV10,P35613,P09601,Q13555,Q9UBM7,Q9H4L5,O00400,Q15800,Q9Y680,Q9P2K2,Q15363,Q9UBV2,O14735,Q9BUR5,P16435,O95070,P48449,Q8NF37,P39687,Q9BUN8,O15269,Q9P2E9,P10321,Q8N2K0,Q6P1A2,Q96A33,Q96KC8,P16615,O95674,A1L0T0,Q9P035,Q13217,Q01105,P51572,O43681,Q9H089,Q15904,Q8WXH0,Q6Y7W6
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
519,518,5,8,514,528,523,15,16,19,535,532,26,545,29,33,542,35,539,38,39,40,558,43,47,554,562,51,52,563,567,59,62,63,65,69,70,77,79,86,90,91,102,103,109,118,120,130,131,134,135,136,142,147,154,159,161,165,166,172,175,179,188,190,191,192,193,195,196,201,205,204,206,219,222,225,227,233,236,239,248,250,254,258,262,272,277,275,283,289,298,307,308,311,315,320,328,334,346,359,358,352,367,378,376,372,384,379,393,388,386,396,405,401,413,415,428,423,425,424,442,445,441,438,448,455,463,470,469,467,494,488,506,516
|
636,448,159,352,1099,2463,637,131,973,710,638,379,1488,1018,1759,63,33,1453,109,415,1454,2273,195,1121,1489,219,1122,1810,467,190,196,1732,227,656,201,1490,2326,1733,887,206,1991,562,147,1637,1174,2354,1348,876,1250,798,386,592,142,1735,1349,888,275,2389,901,1427,438,1036,799,657,262,2431,188,2487,1198,859,1228,539,2648,1080,70,718,861,2313,1380,334,1058,423,38,2564,1641,161,1127,2448,890,388,441,819,2524,979,2534,2296,1555,1353,2505,2535,1301,15,1997,2543,2172,1492,863,1612,2408,1998,1408,2233,1023,2451,744,1003,1302,35,1180,289,1381,1326,1849,1061,1234,328,1522,2299,154,86,2000,401,604,1740,51,2199,2092,2200,563,1460,396,982,692,1765,2069,1327,1878,701,1969,233,1409,720,1201,469,277,90,2215,1681,2156,2376,2178,2094,2377,1744,985,649,2536,1006,2283,2137,2345,823,1905,2519,2420,1563,1822,248,1823,2260,1465,2378,1594,650,1939,865,2422,2553,2238,165,135,2034,2179,514,1278,961,470,1855,1528,236,2456,2691,1026,204,2481,179,1715,1062,554,827,1616,1160,1133,2220,1084,1204,532,463,26,346,254,1617,29,52,1440,311,1718,175,1010,2119,724,927,2347,1442,694,1335,372,166,2397,2138,1064,43,1163,944,2043,367,488,2556,65,2671,867,225,535,47,869,695,2008,2204,1750,963,283,542,802,424,1443,1691,1164,516,599,103,2494,831,684,667,620,102,870,1260,19,1110,558,40,425,79,1500,1419,1862,567,727,1534,405,715,518,1211,258,2011,2292,118,77,1475,1368,1091,761,2012,506,519,716,659,1284,193,1397,2125,777,1342,442,1369,1138,965,120,1093,272,523,445,192,172,1447,669,1835,2659,5,545,764,1914,16,298,849,1372,1538,307,413,393,320,752,1784,494,1215,39,672,239,191,358,1541,8,315,949,1051,1245,69,1666,1095,308,1070,611,1033,875,2143,91,1172,1920,1247,250,455,969,1484,428,686,376,59,1867,359,205,384,1582,674,1118,2600,568,2570,1376,134,1955,1001,1345,222,62,935,812,1119,130,1264,2502,1929,528,136,1807,936,1515,378,920
|
0.4560011507642696,0.7559915142019157,1.7531245573462935,0.9478015835630615,-0.001127805810301048,-0.9645715603540274,0.4560011507642696,1.94987853311504,0.09320779573109034,0.35249256146592,0.4560011507642696,0.8936333486288025,-0.243884846085324,0.061932036437784624,-0.3945665116133365,2.472830381816948,2.953902538225382,-0.22738159228350283,2.0626573264796644,0.8114351982042777,-0.22738159228350283,-0.7441656379825385,1.500741864308918,-0.017000063987738737,-0.243884846085324,1.3892066414158972,-0.017000063987738737,-0.4285902586631195,0.7140629338857863,1.5374592754176952,1.4884520937953238,-0.377629316099032,1.364133559046907,0.42661358757948437,1.4761368247888418,-0.243884846085324,-0.7984810752691569,-0.377629316099032,0.17067086843316673,1.4514293500729303,-0.5318785727630885,0.5577119571515898,1.858096452664984,-0.3271128392759249,-0.04887504627384466,-0.8349780072652183,-0.1618337970909173,0.18604079096340007,-0.09701742595051951,0.24711890736266962,0.8800131050184969,0.5143375851029162,1.8811746612706568,-0.377629316099032,-0.1618337970909173,0.17067086843316673,1.1985189212016558,-0.8717077957387307,0.1552603482535626,-0.21092513401942328,0.7699015142883784,0.04623097246479662,0.24711890736266962,0.42661358757948437,1.249972588664049,-0.9272458982666049,1.549648138953408,-1.0021412347204408,-0.0648782670729416,0.2013703373493341,-0.08092564237043719,0.5864509778300103,-1.5557427245210897,0.014701291299391921,2.420435656490256,0.3375549865593367,0.2013703373493341,-0.7803189764195482,-0.17815150752877743,0.9881035286247505,0.030487470396744938,0.7976231963964028,2.8665746612984697,-1.174315546728808,-0.3271128392759249,1.7413460338386124,-0.017000063987738737,-0.9458784336451688,0.17067086843316673,0.8800131050184969,0.7699015142883784,0.23190917857868676,-1.07802603682358,0.09320779573109034,-1.0971550435827746,-0.7622139544215649,-0.27703285170862874,-0.1618337970909173,-1.0399582580540272,-1.0971550435827746,-0.12933524422973913,3.4883696583674233,-0.5318785727630885,-1.1163480492502467,-0.6547618971329058,-0.243884846085324,0.2013703373493341,-0.31037139890127774,-0.8901609796463711,-0.5318785727630885,-0.19451519653859392,-0.7082376548394596,0.061932036437784624,-0.9458784336451688,0.30756485716682186,0.07759089922445578,-0.12933524422973913,2.915245805395765,-0.04887504627384466,1.1596327314267856,-0.17815150752877743,-0.14556179771058245,-0.4456774203599463,0.030487470396744938,-0.08092564237043719,1.0014765288625636,-0.26043517265107846,-0.7622139544215649,1.8233108238857811,2.303532579472338,-0.5318785727630885,0.852677740649789,0.4998078409542412,-0.377629316099032,2.637490586614291,-0.6725321288961622,-0.5842230489234069,-0.6725321288961622,0.5577119571515898,-0.22738159228350283,0.8663612864956289,0.09320779573109034,0.382253743928895,-0.3945665116133365,-0.566722147958878,-0.14556179771058245,-0.462815185693309,0.3673920803157548,-0.514535240785251,1.338953943492325,-0.19451519653859392,0.3375549865593367,-0.0648782670729416,0.7140629338857863,1.1985189212016558,2.282030613119506,-0.6903572636353332,-0.3439027766845685,-0.6370462182791121,-0.8533136017184143,-0.6547618971329058,-0.5842230489234069,-0.8533136017184143,-0.377629316099032,0.09320779573109034,0.4413258066063131,-1.0971550435827746,0.07759089922445578,-0.7441656379825385,-0.6193847456466299,-0.8167006259673601,0.23190917857868676,-0.4800038669191164,-1.0589605873257606,-0.9086735477231258,-0.27703285170862874,-0.4285902586631195,1.3009827009421377,-0.4285902586631195,-0.7261736594651729,-0.22738159228350283,-0.8533136017184143,-0.29367816551779385,0.4413258066063131,-0.4972437792285436,0.2013703373493341,-0.9086735477231258,-1.1356055001499545,-0.7082376548394596,1.717718863168589,1.9270649969621256,-0.5492740993843713,-0.6547618971329058,0.6292972508241202,-0.11315387381905866,0.10878295888408213,0.7140629338857863,-0.4456774203599463,-0.26043517265107846,1.3263238911225568,-0.9458784336451688,-3.291501686426648,0.061932036437784624,1.463795947164361,-0.983325689072196,1.6222608747574856,-0.36074150382824394,0.030487470396744938,0.5720990698697436,0.23190917857868676,-0.31037139890127774,-0.032915728384741015,-0.017000063987738737,-0.6903572636353332,0.014701291299391921,-0.0648782670729416,0.6007678594820233,0.7280723875131836,3.0114283478612625,0.9612662003264605,1.2882713222080582,-0.31037139890127774,3.0018786097104724,2.6273302312130475,-0.21092513401942328,1.0810841689575286,-0.36074150382824394,1.658237345935038,0.07759089922445578,-0.6017771358819511,0.3375549865593367,0.13980900706892938,-0.8167006259673601,-0.21092513401942328,0.382253743928895,-0.14556179771058245,0.9072221686279333,1.705870022831379,-0.8717077957387307,-0.6193847456466299,0.030487470396744938,2.7878758792557337,-0.032915728384741015,0.12431661965225804,-0.5492740993843713,0.9207797152191141,0.6718330237408522,-1.1356055001499545,2.45192727608413,-1.7672271447732948,0.2013703373493341,1.3766833583434828,0.6007678594820233,2.7381629713773825,0.2013703373493341,0.382253743928895,-0.5318785727630885,-0.6725321288961622,-0.377629316099032,0.10878295888408213,1.1855852561088989,0.5864509778300103,0.24711890736266962,0.7976231963964028,-0.21092513401942328,-0.3439027766845685,-0.032915728384741015,0.6292972508241202,0.5143375851029162,2.15137339820128,-1.0021412347204408,0.23190917857868676,0.39707775152061925,0.41186430071853863,0.48524197874422104,2.1623710072700724,0.2013703373493341,-0.09701742595051951,3.2085718590601604,-0.001127805810301048,0.5720990698697436,2.8371826720644844,0.7976231963964028,2.3463066784162883,-0.243884846085324,-0.19451519653859392,-0.4456774203599463,0.5577119571515898,0.3375549865593367,-0.26043517265107846,0.852677740649789,0.35249256146592,0.6292972508241202,-0.0648782670729416,1.275532592400303,-0.5318785727630885,-0.7441656379825385,2.0065339889232616,2.3569527332268905,-0.22738159228350283,-0.1618337970909173,0.014701291299391921,0.2925118928589216,-0.5318785727630885,0.6435101106197167,0.6292972508241202,0.35249256146592,0.42661358757948437,-0.11315387381905866,1.5130062457371627,-0.17815150752877743,-0.6017771358819511,0.2774200528143013,-0.14556179771058245,0.7699015142883784,-0.1618337970909173,-0.017000063987738737,0.10878295888408213,1.9952458014491112,0.014701291299391921,1.211424359795403,0.6150498919054735,0.7699015142883784,1.5252453467763538,1.6701813099617207,-0.21092513401942328,0.41186430071853863,-0.4285902586631195,-1.6393962657387167,4.00405433878558,0.5864509778300103,0.2925118928589216,-0.4800038669191164,3.4352105279543297,1.1204890033550043,0.21665972726603153,-0.1618337970909173,-0.26043517265107846,1.0942483489073807,0.8252148517366122,0.8800131050184969,1.0414145845970093,0.30756485716682186,-0.3945665116133365,0.6718330237408522,-0.0648782670729416,2.8567932128917906,0.41186430071853863,1.3263238911225568,1.5374592754176952,0.9478015835630615,-0.26043517265107846,3.627900422577668,1.0546674241385827,0.12431661965225804,0.04623097246479662,-0.08092564237043719,2.4309512128450095,-0.3271128392759249,0.014701291299391921,1.0942483489073807,0.030487470396744938,0.4998078409542412,0.061932036437784624,0.2013703373493341,-0.6193847456466299,2.260451272324659,-0.032915728384741015,-0.4800038669191164,-0.08092564237043719,1.3009827009421377,0.7559915142019157,0.10878295888408213,-0.22738159228350283,0.7976231963964028,0.39707775152061925,0.9072221686279333,2.5351071762344404,-0.4456774203599463,0.9478015835630615,1.463795947164361,0.8936333486288025,-0.27703285170862874,0.41186430071853863,-0.001127805810301048,-1.2722506277254433,0.5577119571515898,-1.174315546728808,-0.1618337970909173,1.9384826617323367,-0.4972437792285436,0.09320779573109034,-0.14556179771058245,1.3892066414158972,2.4832547399290448,0.13980900706892938,0.24711890736266962,-0.001127805810301048,1.9612526973306057,-0.09701742595051951,-1.0210186165202892,-0.4800038669191164,0.6150498919054735,1.9270649969621256,-0.4115533912456994,0.13980900706892938,-0.243884846085324,0.9072221686279333,0.1552603482535626
| 2,702
|
Organic acid transmembrane transport
| 10
| 29
| 3.472416
| 0.000516
|
Q9Y619,Q9H2H9,P23786,P33527,Q9UBX3,Q9BQT8,O43772,Q9H2D1,P08183,P31749
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
226,198,105,13,144,146,83,53,54,189
|
83,921,1637,1151,957,54,1057,889,105,615,189,1849,13,457,1969,271,1159,1415,1475,1503,559,146,53,198,1629,144,420,1805,226
|
2.3249577453845984,0.13980900706892938,-0.3271128392759249,-0.032915728384741015,0.10878295888408213,2.5762697271805473,0.030487470396744938,0.17067086843316673,2.096080199744481,0.48524197874422104,1.549648138953408,-0.4456774203599463,3.497184563628806,0.7420485262435965,-0.514535240785251,1.211424359795403,-0.032915728384741015,-0.19451519653859392,-0.22738159228350283,-0.243884846085324,0.5720990698697436,1.8696467178692489,2.5967459172501477,1.4884520937953238,-0.31037139890127774,1.8811746612706568,0.8114351982042777,-0.4115533912456994,1.3766833583434828
| 2,702
|
Ion transmembrane transport
| 51
| 139
| 3.445266
| 0.00057
|
O15439,Q70HW3,Q8TB61,P78417,P21796,P13073,P33527,P53985,Q9UBX3,Q9HD26,Q9BQT8,O75844,Q96PU5,Q8NEW0,Q96ES6,Q7KZN9,Q9C0H2,Q9UHG3,P45880,P05023,Q9UJS0,Q9BPX6,Q9Y6M7,Q9Y277,Q9H2D1,P08183,Q8NB49,O75964,Q9Y376,O75027,P16615,P20674,O43865,Q9HD20,P56134,P25705,P41440,Q8N4V1,O43772,O43808,P00403,Q9UDW1,P06576,Q9Y619,Q6P4A7,O00400,O95202,P51790,P24539,Q13423,P04920
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
380,1,258,513,11,395,13,271,144,538,146,147,280,152,279,409,31,32,34,539,420,303,304,437,53,54,567,184,570,312,441,572,196,69,573,451,457,79,83,337,338,87,215,226,97,352,363,242,371,119,502
|
2055,352,1586,380,582,83,337,196,2057,312,2550,2531,1734,921,147,1637,1992,184,363,1151,338,502,539,1252,860,957,215,1229,2327,1323,54,1057,1230,1175,2062,978,614,395,441,1874,2464,1022,572,1101,2406,2407,11,941,371,451,2408,2233,2507,1381,2197,13,1614,1082,1876,457,1740,34,1356,2508,1969,755,242,1463,271,1435,1821,573,904,841,1563,1158,865,513,1278,2115,1159,1360,1767,2220,119,1257,1028,2119,1335,1415,2556,760,97,1,409,1110,2099,79,567,1660,152,258,1475,1621,2348,2427,279,1093,1503,280,2659,1031,303,146,609,31,1215,53,1629,896,69,538,2167,144,87,2600,32,1217,420,1073,1376,437,1805,570,1545,783,226,2549,304
|
-0.566722147958878,0.9478015835630615,-0.29367816551779385,0.8936333486288025,0.5288313967073893,2.3249577453845984,0.9747001337238531,1.4884520937953238,-0.566722147958878,1.0678905729851498,-1.1356055001499545,-1.0971550435827746,-0.377629316099032,0.13980900706892938,1.858096452664984,-0.3271128392759249,-0.5318785727630885,1.586065401491409,0.9207797152191141,-0.032915728384741015,0.9747001337238531,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,0.10878295888408213,1.4017035243632918,-0.08092564237043719,-0.7984810752691569,-0.14556179771058245,2.5762697271805473,0.030487470396744938,-0.08092564237043719,-0.04887504627384466,-0.566722147958878,0.09320779573109034,0.48524197874422104,0.8663612864956289,0.7699015142883784,-0.462815185693309,-0.9645715603540274,0.061932036437784624,0.5432894598416556,-0.001127805810301048,-0.8901609796463711,-0.8901609796463711,3.541068752096914,0.12431661965225804,0.9072221686279333,0.7559915142019157,-0.8901609796463711,-0.7082376548394596,-1.0399582580540272,-0.17815150752877743,-0.6725321288961622,3.497184563628806,-0.31037139890127774,0.014701291299391921,-0.462815185693309,0.7420485262435965,-0.377629316099032,2.953902538225382,-0.1618337970909173,-1.0399582580540272,-0.514535240785251,0.2925118928589216,1.3136668502909221,-0.22738159228350283,1.211424359795403,-0.21092513401942328,-0.4285902586631195,0.5432894598416556,0.1552603482535626,0.21665972726603153,-0.27703285170862874,-0.032915728384741015,0.2013703373493341,0.6292972508241202,-0.11315387381905866,-0.6017771358819511,-0.032915728384741015,-0.1618337970909173,-0.3945665116133365,-0.6903572636353332,1.9952458014491112,-0.09701742595051951,0.061932036437784624,-0.6017771358819511,-0.14556179771058245,-0.19451519653859392,-1.1356055001499545,0.2925118928589216,2.217058138603211,4.343126506682812,0.8389623139505717,-0.001127805810301048,-0.5842230489234069,2.3463066784162883,0.5577119571515898,-0.3271128392759249,1.8349285964616746,1.275532592400303,-0.22738159228350283,-0.31037139890127774,-0.8167006259673601,-0.9086735477231258,1.1985189212016558,0.014701291299391921,-0.243884846085324,1.1985189212016558,-1.6393962657387167,0.061932036437784624,1.1073832487263275,1.8696467178692489,0.4998078409542412,2.9827338068802134,-0.0648782670729416,2.5967459172501477,-0.31037139890127774,0.17067086843316673,2.4309512128450095,0.6007678594820233,-0.6370462182791121,1.8811746612706568,2.303532579472338,-1.2722506277254433,2.9731386427052393,-0.0648782670729416,0.8114351982042777,0.030487470396744938,-0.1618337970909173,0.7837786881907414,-0.4115533912456994,0.5577119571515898,-0.26043517265107846,0.2774200528143013,1.3766833583434828,-1.1163480492502467,1.1073832487263275
| 2,702
|
Active ion transmembrane transporter activity
| 22
| 43
| 3.42955
| 0.000605
|
O15439,P13073,P33527,Q96ES6,Q7KZN9,P05023,Q9Y5K8,Q96QD8,Q9Y6M7,P16615,P20674,Q9HD20,Q9H2H9,P41440,P00403,Q9UDW1,P06576,Q9BXP2,O00400,O95202,P51790,P04920
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
380,395,13,279,409,539,561,559,304,441,572,69,198,457,338,87,215,609,352,363,242,502
|
352,380,363,338,502,539,1252,860,215,1057,1230,1175,978,614,395,441,1022,572,1101,2406,941,2197,13,1082,1876,457,242,1463,841,1278,2115,1159,409,279,559,609,198,69,87,1217,1805,561,304
|
0.9478015835630615,0.8936333486288025,0.9207797152191141,0.9747001337238531,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,1.4017035243632918,0.030487470396744938,-0.08092564237043719,-0.04887504627384466,0.09320779573109034,0.48524197874422104,0.8663612864956289,0.7699015142883784,0.061932036437784624,0.5432894598416556,-0.001127805810301048,-0.8901609796463711,0.12431661965225804,-0.6725321288961622,3.497184563628806,0.014701291299391921,-0.462815185693309,0.7420485262435965,1.3136668502909221,-0.22738159228350283,0.21665972726603153,-0.11315387381905866,-0.6017771358819511,-0.032915728384741015,0.8389623139505717,1.1985189212016558,0.5720990698697436,0.4998078409542412,1.4884520937953238,2.4309512128450095,2.303532579472338,-0.0648782670729416,-0.4115533912456994,0.5720990698697436,1.1073832487263275
| 2,702
|
Mitochondrial transmembrane transport
| 18
| 46
| 3.425934
| 0.000613
|
Q9Y619,Q6P4A7,Q99595,O14925,Q9UJS0,O95831,P23786,P21796,Q15388,Q9BPX6,O95202,Q9BQT8,O43772,Q9H2D1,P24539,O75027,P06576,O75964
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
226,97,2,344,420,9,105,11,366,303,363,146,83,53,371,312,215,184
|
344,549,83,312,1734,921,1992,184,1225,363,1151,9,785,860,215,2133,978,614,11,105,371,451,1614,2508,573,904,2115,366,1043,97,1660,2292,1621,2427,1503,2,303,146,634,53,1629,1374,420,1073,783,226
|
0.9612662003264605,0.5720990698697436,2.3249577453845984,1.0678905729851498,-0.377629316099032,0.13980900706892938,-0.5318785727630885,1.586065401491409,-0.08092564237043719,0.9207797152191141,-0.032915728384741015,3.601980510099323,0.2622891279230963,0.2013703373493341,1.4017035243632918,-0.6193847456466299,0.09320779573109034,0.48524197874422104,3.541068752096914,2.096080199744481,0.9072221686279333,0.7559915142019157,-0.31037139890127774,-1.0399582580540272,0.5432894598416556,0.1552603482535626,-0.6017771358819511,0.9207797152191141,0.04623097246479662,2.217058138603211,-0.3271128392759249,-0.7441656379825385,-0.31037139890127774,-0.9086735477231258,-0.243884846085324,4.084595663215114,1.1073832487263275,1.8696467178692489,0.4706398114973275,2.5967459172501477,-0.31037139890127774,-0.1618337970909173,0.8114351982042777,0.030487470396744938,0.2774200528143013,1.3766833583434828
| 2,702
|
Anion transmembrane transporter activity
| 25
| 46
| 3.425485
| 0.000614
|
O15439,Q8TB61,P21796,P33527,P53985,Q9UBX3,Q9BQT8,Q9C0H2,P45880,Q9UJS0,Q96QD8,Q9Y6M7,Q9Y277,Q9H2D1,Q9H2H9,P41440,O43808,O43681,Q9BXP2,Q9Y619,O00400,P12236,P51790,Q99808,P04920
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
380,258,11,13,271,144,146,31,34,420,559,304,437,53,198,457,337,467,609,226,352,614,242,633,502
|
2055,352,380,467,337,921,1151,502,860,1057,889,978,614,11,13,457,34,242,1463,271,1159,1415,760,2657,642,1443,258,1475,1503,559,669,633,146,609,31,53,198,1629,896,144,420,437,1805,226,2549,304
|
-0.566722147958878,0.9478015835630615,0.8936333486288025,0.7140629338857863,0.9747001337238531,0.13980900706892938,-0.032915728384741015,0.6435101106197167,0.2013703373493341,0.030487470396744938,0.17067086843316673,0.09320779573109034,0.48524197874422104,3.541068752096914,3.497184563628806,0.7420485262435965,2.953902538225382,1.3136668502909221,-0.22738159228350283,1.211424359795403,-0.032915728384741015,-0.19451519653859392,0.2925118928589216,-1.6183674545716196,0.4560011507642696,-0.21092513401942328,1.275532592400303,-0.22738159228350283,-0.243884846085324,0.5720990698697436,0.41186430071853863,0.4706398114973275,1.8696467178692489,0.4998078409542412,2.9827338068802134,2.5967459172501477,1.4884520937953238,-0.31037139890127774,0.17067086843316673,1.8811746612706568,0.8114351982042777,0.7837786881907414,-0.4115533912456994,1.3766833583434828,-1.1163480492502467,1.1073832487263275
| 2,702
|
Organic anion transmembrane transporter activity
| 17
| 31
| 3.396743
| 0.000682
|
O15439,Q9Y619,Q8TB61,Q9UJS0,O00400,Q9H2H9,Q96QD8,P41440,P33527,P53985,Q9UBX3,Q9Y6M7,Q9BQT8,P12236,Q9H2D1,O43808,Q99808
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
380,226,258,420,352,198,559,457,13,271,144,304,146,614,53,337,633
|
352,380,337,921,1151,860,1057,889,978,614,13,457,271,1159,1415,642,1443,258,1503,559,633,146,53,198,1629,896,144,420,1805,226,304
|
0.9478015835630615,0.8936333486288025,0.9747001337238531,0.13980900706892938,-0.032915728384741015,0.2013703373493341,0.030487470396744938,0.17067086843316673,0.09320779573109034,0.48524197874422104,3.497184563628806,0.7420485262435965,1.211424359795403,-0.032915728384741015,-0.19451519653859392,0.4560011507642696,-0.21092513401942328,1.275532592400303,-0.243884846085324,0.5720990698697436,0.4706398114973275,1.8696467178692489,2.5967459172501477,1.4884520937953238,-0.31037139890127774,0.17067086843316673,1.8811746612706568,0.8114351982042777,-0.4115533912456994,1.3766833583434828,1.1073832487263275
| 2,702
|
Carboxylic acid transport
| 12
| 30
| 3.392916
| 0.000692
|
O15439,Q9Y619,P07602,Q9UJS0,Q9H2H9,Q9NZJ7,P33527,P53985,Q9UBX3,Q9BQT8,Q9H2D1,P14174
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
380,226,4,420,198,427,13,271,144,146,53,122
|
380,921,1637,1151,818,957,4,1057,122,1233,615,13,457,1969,271,1159,1415,1443,1475,1503,559,146,53,198,1629,427,144,420,1805,226
|
0.8936333486288025,0.13980900706892938,-0.3271128392759249,-0.032915728384741015,0.23190917857868676,0.10878295888408213,4.00405433878558,0.030487470396744938,1.983936246561302,-0.08092564237043719,0.48524197874422104,3.497184563628806,0.7420485262435965,-0.514535240785251,1.211424359795403,-0.032915728384741015,-0.19451519653859392,-0.21092513401942328,-0.22738159228350283,-0.243884846085324,0.5720990698697436,1.8696467178692489,2.5967459172501477,1.4884520937953238,-0.31037139890127774,0.7976231963964028,1.8811746612706568,0.8114351982042777,-0.4115533912456994,1.3766833583434828
| 2,702
|
Transport of small molecules
| 56
| 147
| 3.381172
| 0.000722
|
O15439,Q70HW3,Q8TB61,P38571,P21796,P28072,P33527,Q10713,P53985,Q9UBX3,Q96PU5,Q8NEW0,O00231,P28074,P35611,Q9BUN8,Q9UEY8,Q9C0H2,P40855,P45880,P30519,P05023,Q9Y5K8,Q96QD8,Q9Y487,P05198,O75832,Q9BPX6,Q9Y6M7,P20618,Q9Y277,P08183,Q8NB49,O75027,P16615,O15118,Q8WTV0,Q9HD20,Q9H2H9,P61289,P35613,P09601,Q8N4V1,Q93050,Q13555,O00400,P28070,P60900,O95202,Q15904,P49721,P51790,Q9UL46,P61916,Q9UBV2,P04920
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
380,1,258,389,11,139,13,397,271,144,280,152,274,151,408,413,546,31,288,34,35,539,561,559,41,551,302,303,304,178,437,54,567,312,441,63,324,69,198,583,328,334,79,82,346,352,355,482,363,488,114,242,377,248,384,502
|
274,2628,2054,352,2107,2109,63,380,955,312,1734,887,302,2622,1250,2212,363,1961,665,502,539,1252,860,551,718,54,1057,976,334,1154,889,978,614,1268,441,1874,1552,1022,1520,178,1101,2406,2296,11,941,2065,1270,1038,2066,2371,355,139,151,615,35,1381,13,1818,408,328,2477,1355,1082,389,1876,288,2409,2030,34,1461,2114,114,2282,242,1463,756,271,1821,2094,482,583,841,248,1329,1971,2218,1940,2358,1202,1278,1564,2035,826,397,1616,2180,346,2554,2662,2040,1415,488,760,1443,1,2384,79,567,1983,1660,152,258,1475,324,1621,1662,82,1370,280,559,791,585,2082,1031,764,633,303,413,31,1215,198,69,1072,384,144,546,1217,1073,377,2209,2084,437,1805,41,783,561,304
|
1.1985189212016558,-1.4325193129919627,-0.566722147958878,0.9478015835630615,-0.6017771358819511,-0.6017771358819511,2.472830381816948,0.8936333486288025,0.10878295888408213,1.0678905729851498,-0.377629316099032,0.17067086843316673,1.1073832487263275,-1.3718907863996646,-0.09701742595051951,-0.6903572636353332,0.9207797152191141,-0.514535240785251,0.41186430071853863,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,0.5720990698697436,0.3375549865593367,2.5762697271805473,0.030487470396744938,0.09320779573109034,0.9881035286247505,-0.032915728384741015,0.17067086843316673,0.09320779573109034,0.48524197874422104,-0.11315387381905866,0.7699015142883784,-0.462815185693309,-0.27703285170862874,0.061932036437784624,-0.26043517265107846,1.6342772292786218,-0.001127805810301048,-0.8901609796463711,-0.7622139544215649,3.541068752096914,0.12431661965225804,-0.566722147958878,-0.11315387381905866,0.04623097246479662,-0.566722147958878,-0.8533136017184143,0.9478015835630615,1.904163939767927,1.8349285964616746,0.48524197874422104,2.915245805395765,-0.17815150752877743,3.497184563628806,-0.4285902586631195,0.8389623139505717,1.0014765288625636,-0.983325689072196,-0.1618337970909173,0.014701291299391921,0.8800131050184969,-0.462815185693309,1.1726232359899564,-0.8901609796463711,-0.5492740993843713,2.953902538225382,-0.22738159228350283,-0.6017771358819511,2.0290465958413018,-0.7441656379825385,1.3136668502909221,-0.22738159228350283,0.2925118928589216,1.211424359795403,-0.4285902586631195,-0.5842230489234069,0.6859434192423728,0.5288313967073893,0.21665972726603153,1.3009827009421377,-0.14556179771058245,-0.514535240785251,-0.6903572636353332,-0.4972437792285436,-0.8349780072652183,-0.0648782670729416,-0.11315387381905866,-0.27703285170862874,-0.5492740993843713,0.23190917857868676,0.8663612864956289,-0.31037139890127774,-0.6547618971329058,0.9612662003264605,-1.1356055001499545,-1.7029527383730034,-0.5492740993843713,-0.19451519653859392,0.6718330237408522,0.2925118928589216,-0.21092513401942328,4.343126506682812,-0.8533136017184143,2.3463066784162883,0.5577119571515898,-0.514535240785251,-0.3271128392759249,1.8349285964616746,1.275532592400303,-0.22738159228350283,1.0281319155612654,-0.31037139890127774,-0.3271128392759249,2.3356417057869807,-0.1618337970909173,1.1985189212016558,0.5720990698697436,0.2622891279230963,0.5288313967073893,-0.566722147958878,0.061932036437784624,0.2925118928589216,0.4706398114973275,1.1073832487263275,0.8252148517366122,2.9827338068802134,-0.0648782670729416,1.4884520937953238,2.4309512128450095,0.030487470396744938,0.8936333486288025,1.8811746612706568,0.5864509778300103,-0.0648782670729416,0.030487470396744938,0.9072221686279333,-0.6725321288961622,-0.566722147958878,0.7837786881907414,-0.4115533912456994,2.8371826720644844,0.2774200528143013,0.5720990698697436,1.1073832487263275
| 2,702
|
Intrinsic component of plasma membrane
| 34
| 76
| 3.37158
| 0.000747
|
O00560,Q92542,A0FGR8,P11279,P36551,P33527,Q9BTU6,P53985,O96005,Q9Y4G8,Q9NR28,O00264,P11717,Q9UJS0,P05023,Q96QD8,P10321,Q8N2K0,O43657,O60637,Q8NB49,P16615,Q9UIQ6,O15118,Q8WTV0,Q9H2H9,P35613,P41440,P51572,O00400,Q86UP2,P51790,Q99808,Q13641
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
637,519,636,387,269,13,399,271,145,662,410,159,417,420,539,559,423,425,48,49,567,441,64,63,324,198,328,457,469,352,620,242,633,254
|
636,159,352,637,1404,815,63,1121,48,1636,49,1174,799,145,665,2487,539,1252,860,957,423,1900,889,387,417,978,441,1199,2524,1022,1676,941,1408,13,1818,328,269,457,1969,469,242,271,1821,2320,2115,1159,757,1133,1161,254,2285,2119,1335,1415,620,1773,425,567,1211,1475,324,519,559,764,848,633,399,1215,198,410,64,420,1001,1805,662,1377
|
0.4560011507642696,1.7531245573462935,0.9478015835630615,0.4560011507642696,-0.19451519653859392,0.23190917857868676,2.472830381816948,-0.017000063987738737,2.6980955379470237,-0.3271128392759249,2.6577600342457113,-0.04887504627384466,0.24711890736266962,1.8696467178692489,0.41186430071853863,-1.0021412347204408,0.5864509778300103,-0.09701742595051951,0.2013703373493341,0.10878295888408213,0.7976231963964028,-0.4800038669191164,0.17067086843316673,0.8800131050184969,0.8114351982042777,0.09320779573109034,0.7699015142883784,-0.0648782670729416,-1.07802603682358,0.061932036437784624,-0.3439027766845685,0.12431661965225804,-0.19451519653859392,3.497184563628806,-0.4285902586631195,1.0014765288625636,1.224301699534718,0.7420485262435965,-0.514535240785251,0.7140629338857863,1.3136668502909221,1.211424359795403,-0.4285902586631195,-0.7803189764195482,-0.6017771358819511,-0.032915728384741015,0.2925118928589216,-0.017000063987738737,-0.032915728384741015,1.2882713222080582,-0.7441656379825385,-0.6017771358819511,-0.14556179771058245,-0.19451519653859392,0.48524197874422104,-0.3945665116133365,0.7976231963964028,0.5577119571515898,-0.0648782670729416,-0.22738159228350283,1.0281319155612654,0.6292972508241202,0.5720990698697436,0.2925118928589216,0.21665972726603153,0.4706398114973275,0.8663612864956289,-0.0648782670729416,1.4884520937953238,0.8389623139505717,2.472830381816948,0.8114351982042777,0.09320779573109034,-0.4115533912456994,0.42661358757948437,-0.1618337970909173
| 2,702
|
Receptor
| 13
| 33
| 3.347474
| 0.000816
|
Q9NS69,O15173,O15118,Q5KU26,Q99720,Q8WTV0,P11279,Q9Y5M8,P35613,P24390,Q14739,Q14108,O00264
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
0,33,63,163,5,324,387,136,328,15,175,29,159
|
159,1404,815,63,33,665,957,1080,2313,1963,1058,1900,387,417,1300,1676,15,328,2320,1161,29,175,1415,163,324,2348,1031,5,0,568,687,136,2548
|
1.7531245573462935,-0.19451519653859392,0.23190917857868676,2.472830381816948,2.953902538225382,0.41186430071853863,0.10878295888408213,0.014701291299391921,-0.7803189764195482,-0.514535240785251,0.030487470396744938,-0.4800038669191164,0.8800131050184969,0.8114351982042777,-0.12933524422973913,-0.3439027766845685,3.4883696583674233,1.0014765288625636,-0.7803189764195482,-0.032915728384741015,3.0018786097104724,1.658237345935038,-0.19451519653859392,1.7295441678744543,1.0281319155612654,-0.8167006259673601,0.061932036437784624,4.00405433878558,4.48719359410752,0.5577119571515898,0.39707775152061925,1.9270649969621256,-1.1163480492502467
| 2,702
|
Organic acid transport
| 16
| 41
| 3.332029
| 0.000862
|
O15439,Q9Y619,Q6P4A7,Q9UJS0,Q9H2H9,P23786,P33527,P53985,Q9UBX3,Q9BQT8,O43772,Q9H2D1,P08183,O43808,P14174,P31749
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
380,226,97,420,198,105,13,271,144,146,83,53,54,337,122,189
|
380,83,337,921,1637,1151,1427,2432,818,957,2275,54,1057,889,122,1233,105,615,1711,189,1849,13,457,1969,271,2567,1159,1415,1443,97,1475,1503,559,146,53,198,1629,144,420,1805,226
|
0.8936333486288025,2.3249577453845984,0.9747001337238531,0.13980900706892938,-0.3271128392759249,-0.032915728384741015,-0.21092513401942328,-0.9272458982666049,0.23190917857868676,0.10878295888408213,-0.7441656379825385,2.5762697271805473,0.030487470396744938,0.17067086843316673,1.983936246561302,-0.08092564237043719,2.096080199744481,0.48524197874422104,-0.36074150382824394,1.549648138953408,-0.4456774203599463,3.497184563628806,0.7420485262435965,-0.514535240785251,1.211424359795403,-1.174315546728808,-0.032915728384741015,-0.19451519653859392,-0.21092513401942328,2.217058138603211,-0.22738159228350283,-0.243884846085324,0.5720990698697436,1.8696467178692489,2.5967459172501477,1.4884520937953238,-0.31037139890127774,1.8811746612706568,0.8114351982042777,-0.4115533912456994,1.3766833583434828
| 2,702
|
Glycoside hydrolase superfamily [IPR017853]
| 9
| 15
| 3.320947
| 0.000897
|
P07686,O60502,P06865,P06280,P54802,P10253,P04062,P16278,P08236
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
160,74,92,112,50,220,188,93,158
|
74,188,439,112,92,160,1057,158,220,93,1061,50,1718,307,782
|
2.378188367259261,1.549648138953408,0.7699015142883784,2.040271181152975,2.249632405350508,1.7531245573462935,0.030487470396744938,1.7648798340833782,1.3892066414158972,2.2387939765464413,0.030487470396744938,2.6577600342457113,-0.36074150382824394,1.0942483489073807,0.2774200528143013
| 2,702
|
Azurophil granule
| 27
| 64
| 3.311793
| 0.000927
|
O00584,P07602,P11279,P42785,Q8NF37,Q92820,P08236,P07686,P17900,P10619,Q9NZJ7,Q9BTY2,Q07065,P04066,Q99536,Q13217,P07437,P68371,O43681,P06865,P10253,P15586,P16278,O95721,O15260,P06280,P61916
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
131,4,387,12,405,284,158,160,162,38,427,307,179,439,460,463,211,216,467,92,220,221,93,353,109,112,248
|
2352,637,131,2672,109,475,467,1267,1321,353,2431,439,112,92,1229,211,4,160,158,220,38,1059,387,221,93,162,1023,2544,2000,12,1969,564,2070,630,1525,2177,1157,2094,2331,248,216,824,2567,1972,179,463,1769,1281,1534,405,519,284,965,2082,460,1601,2309,307,1215,635,2620,427,1484,2210
|
-0.8349780072652183,0.4560011507642696,1.94987853311504,-1.9200896765948166,2.0626573264796644,0.700019999999374,0.7140629338857863,-0.11315387381905866,-0.14556179771058245,0.9478015835630615,-0.9272458982666049,0.7699015142883784,2.040271181152975,2.249632405350508,-0.08092564237043719,1.4266185504356594,4.00405433878558,1.7531245573462935,1.7648798340833782,1.3892066414158972,2.8665746612984697,0.030487470396744938,0.8800131050184969,1.3892066414158972,2.2387939765464413,1.7295441678744543,0.061932036437784624,-1.1163480492502467,-0.5318785727630885,3.523552992410392,-0.514535240785251,0.5577119571515898,-0.566722147958878,0.4706398114973275,-0.26043517265107846,-0.6547618971329058,-0.032915728384741015,-0.5842230489234069,-0.7984810752691569,1.3009827009421377,1.4017035243632918,0.23190917857868676,-1.174315546728808,-0.514535240785251,1.6222608747574856,0.7280723875131836,-0.3945665116133365,-0.11315387381905866,-0.26043517265107846,0.852677740649789,0.6292972508241202,1.1855852561088989,0.10878295888408213,-0.566722147958878,0.7420485262435965,-0.29367816551779385,-0.7622139544215649,1.0942483489073807,-0.0648782670729416,0.4706398114973275,-1.3518233822249164,0.7976231963964028,-0.22738159228350283,-0.6725321288961622
| 2,702
|
Sphingolipid metabolism
| 12
| 24
| 3.300146
| 0.000966
|
P07686,P17900,P07602,P10619,Q06136,P06865,P06280,P51648,Q96G23,Q13510,P04062,P16278
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,162,4,38,204,92,112,277,120,26,188,93
|
636,415,1454,467,1735,275,188,112,92,4,160,38,93,162,1555,277,204,26,2671,120,1372,1172,427,1484
|
0.4560011507642696,0.8114351982042777,-0.22738159228350283,0.7140629338857863,-0.377629316099032,1.1985189212016558,1.549648138953408,2.040271181152975,2.249632405350508,4.00405433878558,1.7531245573462935,2.8665746612984697,2.2387939765464413,1.7295441678744543,-0.27703285170862874,1.1985189212016558,1.463795947164361,3.0114283478612625,-1.7672271447732948,1.9952458014491112,-0.1618337970909173,-0.032915728384741015,0.7976231963964028,-0.22738159228350283
| 2,702
|
Mental deterioration
| 31
| 82
| 3.263543
| 0.0011
|
P50897,P07602,Q10713,Q9BQE5,O95470,Q13510,Q14108,P07686,P17900,Q9NZJ7,Q9Y487,Q5JTZ9,P54802,P20700,P04062,Q9NQZ5,O15118,P04350,O60313,P35637,O75503,P21964,P00403,O43681,P06865,P16278,Q6PI48,P22626,P61916,Q03164,Q6Y7W6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
3,4,397,16,275,26,29,160,162,427,41,433,50,309,188,60,63,449,326,203,206,207,338,467,92,93,479,354,248,123,516
|
1099,63,467,326,1674,1321,1608,206,592,275,785,338,188,2257,449,92,4,160,922,2194,1154,93,162,1021,309,1431,207,354,2112,2298,1903,203,1082,1876,1712,1740,616,1648,1969,3,2583,2281,50,1411,2094,248,1131,2035,123,1908,2159,397,2498,1203,26,29,541,990,433,726,2359,479,516,2639,1500,2468,2014,1696,780,2659,1863,2609,16,1838,1603,60,1668,427,525,1804,1955,41
|
-0.001127805810301048,2.472830381816948,0.7140629338857863,1.014819277244463,-0.3439027766845685,-0.14556179771058245,-0.31037139890127774,1.4514293500729303,0.5143375851029162,1.1985189212016558,0.2622891279230963,0.9747001337238531,1.549648138953408,-0.7261736594651729,0.7559915142019157,2.249632405350508,4.00405433878558,1.7531245573462935,0.13980900706892938,-0.6725321288961622,-0.032915728384741015,2.2387939765464413,1.7295441678744543,0.061932036437784624,1.0810841689575286,-0.21092513401942328,1.4390369219353498,0.9478015835630615,-0.6017771358819511,-0.7622139544215649,-0.4800038669191164,1.463795947164361,0.014701291299391921,-0.462815185693309,-0.36074150382824394,-0.377629316099032,0.48524197874422104,-0.3271128392759249,-0.514535240785251,4.03639791939681,-1.2132888500172512,-0.7441656379825385,2.6577600342457113,-0.19451519653859392,-0.5842230489234069,1.3009827009421377,-0.017000063987738737,-0.5492740993843713,1.983936246561302,-0.4800038669191164,-0.6370462182791121,0.8663612864956289,-1.0210186165202892,-0.0648782670729416,3.0114283478612625,3.0018786097104724,0.5864509778300103,0.09320779573109034,0.7837786881907414,0.3375549865593367,-0.8349780072652183,0.700019999999374,0.6292972508241202,-1.4937984028764713,-0.243884846085324,-0.9645715603540274,-0.5318785727630885,-0.3439027766845685,0.2774200528143013,-1.6393962657387167,-0.4456774203599463,-1.311898640240956,3.4352105279543297,-0.4285902586631195,-0.29367816551779385,2.5040493921299296,-0.3271128392759249,0.7976231963964028,0.6150498919054735,-0.4115533912456994,-0.4972437792285436,2.8371826720644844
| 2,702
|
Steroid binding
| 10
| 20
| 3.253659
| 0.001139
|
O15118,O15173,P30536,P45880,P21796,P38435,P61916,P04062,Q14108,O00264
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
63,33,289,34,11,86,248,188,29,159
|
159,63,33,887,1250,188,539,1323,11,1555,1353,289,86,34,248,29,2047,1698,1784,358
|
1.7531245573462935,2.472830381816948,2.953902538225382,0.17067086843316673,-0.09701742595051951,1.549648138953408,0.5864509778300103,-0.14556179771058245,3.541068752096914,-0.27703285170862874,-0.1618337970909173,1.1596327314267856,2.303532579472338,2.953902538225382,1.3009827009421377,3.0018786097104724,-0.5492740993843713,-0.3439027766845685,-0.3945665116133365,0.9478015835630615
| 2,702
|
Vascular skin abnormality
| 22
| 95
| 3.237556
| 0.001206
|
P22830,Q8IZA0,O75844,P51648,Q13126,Q14108,P10619,Q9Y487,Q14739,P04062,P31749,Q06136,P21964,Q9Y3Z3,P38435,P00403,Q9NWM8,P16278,P35579,Q08J23,P06280,P02545
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
7,278,147,277,24,29,38,41,175,188,189,204,207,342,86,338,91,93,345,228,112,241
|
1219,1548,1761,656,1811,1223,1608,147,2579,2024,338,241,188,439,112,1429,2336,38,1154,2355,2669,1269,93,1874,1021,1176,2407,1233,1431,207,7,1998,2028,1023,2234,189,1790,840,345,1082,1591,86,1876,1935,924,982,1327,1182,1649,277,1463,1328,2178,1411,1102,1278,1468,1855,1528,1746,204,1973,228,749,24,29,2286,1390,175,926,893,1208,1064,2043,2222,1912,642,1443,1108,278,832,2444,1397,2385,1601,500,2484,1171,91,1097,359,612,342,41,1634
|
-0.08092564237043719,-0.27703285170862874,-0.3945665116133365,0.42661358757948437,-0.4285902586631195,-0.08092564237043719,-0.31037139890127774,1.858096452664984,-1.2132888500172512,-0.5492740993843713,0.9747001337238531,1.3136668502909221,1.549648138953408,0.7699015142883784,2.040271181152975,-0.21092513401942328,-0.8167006259673601,2.8665746612984697,-0.032915728384741015,-0.8349780072652183,-1.7457215321911723,-0.11315387381905866,2.2387939765464413,-0.462815185693309,0.061932036437784624,-0.04887504627384466,-0.8901609796463711,-0.08092564237043719,-0.21092513401942328,1.4390369219353498,3.7135134684721347,-0.5318785727630885,-0.5492740993843713,0.061932036437784624,-0.7082376548394596,1.549648138953408,-0.4115533912456994,0.21665972726603153,0.9612662003264605,0.014701291299391921,-0.29367816551779385,2.303532579472338,-0.462815185693309,-0.4972437792285436,0.13980900706892938,0.09320779573109034,-0.14556179771058245,-0.04887504627384466,-0.3271128392759249,1.1985189212016558,-0.22738159228350283,-0.14556179771058245,-0.6547618971329058,-0.19451519653859392,-0.001127805810301048,-0.11315387381905866,-0.22738159228350283,-0.4456774203599463,-0.26043517265107846,-0.377629316099032,1.463795947164361,-0.514535240785251,1.35155712664995,0.30756485716682186,3.0778580474948067,3.0018786097104724,-0.7441656379825385,-0.17815150752877743,1.658237345935038,0.13980900706892938,0.17067086843316673,-0.0648782670729416,0.030487470396744938,-0.5492740993843713,-0.6903572636353332,-0.4800038669191164,0.4560011507642696,-0.21092513401942328,-0.001127805810301048,1.1985189212016558,0.23190917857868676,-0.9272458982666049,-0.17815150752877743,-0.8533136017184143,-0.29367816551779385,0.6576886443457405,-0.983325689072196,-0.032915728384741015,2.260451272324659,0.014701291299391921,0.9478015835630615,0.4998078409542412,0.9747001337238531,2.8371826720644844,-0.31037139890127774
| 2,702
|
Transport
| 132
| 437
| 3.236285
| 0.001211
|
Q9NS69,Q70HW3,Q99595,Q99720,P21796,P33527,P24390,Q9BQE5,Q8NE01,Q9HD26,O43676,P61970,Q13190,P22695,Q9C0H2,Q8WUH2,Q6NUQ1,P45880,Q14203,O43169,Q6NT16,P05023,Q9Y5K8,Q96QD8,Q9Y487,Q15629,Q7Z3B4,A6NIH7,Q9H2D1,P08183,Q9P2W9,Q8IXU6,Q9Y282,O15118,Q9HD20,Q8N4H5,Q8N4V1,Q93050,O43772,P46379,Q9UDW1,P52292,Q6P4A7,Q6DKK2,P23786,P49321,Q53F19,O00461,Q9Y3B3,Q8N2H4,P37198,O95197,Q9UBX3,Q9BQT8,Q8NEW0,Q9H2V7,Q13505,Q9H1E5,O75964,P31749,Q9H3N1,Q9H2H9,Q9BTX1,Q13432,P06576,O14949,Q9Y619,Q8N1F7,P51790,P61916,Q8TB61,Q9H0H5,P53985,Q96ES6,A0AVF1,O43823,Q8NFH4,O75381,Q9BPX6,Q9Y6M7,O75027,Q8TD16,Q9Y5J7,O15127,Q96L92,O43808,P00403,O14925,Q9H4L5,O00400,P22626,O95721,O95249,Q15388,O95202,Q92945,Q9P0J0,P24539,Q15363,P12270,O96000,O15439,Q9Y2T2,Q9BUR5,O95070,Q9Y5J9,Q9Y5X3,Q9BUN8,P11717,Q9UJS0,Q9P2E9,Q9NZJ7,Q92973,Q9BW83,Q9Y277,P16615,P25705,Q07955,P41440,P51572,O43681,Q15907,Q9P253,Q969Q5,Q9Y6M1,Q9H089,Q8TEX9,Q15904,O75431,Q9Y6C9,P04920,O43633
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
0,1,2,5,11,13,15,16,521,538,20,23,532,530,31,544,542,34,541,36,37,539,561,559,41,43,557,46,53,54,59,61,62,63,69,72,79,82,83,84,87,90,97,100,105,117,124,126,130,132,133,142,144,146,152,153,156,177,184,189,191,198,202,214,215,218,226,238,242,248,258,270,271,279,281,286,291,301,303,304,312,313,317,325,331,337,338,344,358,352,354,353,364,366,363,374,375,371,372,370,369,380,394,393,386,400,414,413,417,420,428,427,434,435,437,441,451,453,457,469,467,477,486,485,498,494,492,488,499,509,502,501
|
281,636,46,1809,2352,1848,2148,2687,2055,352,664,971,126,1586,2310,814,710,2516,1635,344,218,699,1077,1759,63,2022,325,1002,380,1121,36,1146,1489,2253,1705,2610,549,1810,501,20,1895,467,582,1959,83,337,286,956,1034,2087,689,1490,312,1295,1321,2531,1608,301,1733,499,2430,1322,1610,1516,921,1992,184,1348,2212,798,386,1517,731,592,1787,142,363,1251,364,2088,1078,2389,901,1151,353,1961,799,369,785,338,2432,502,539,1252,860,215,54,1057,1230,922,889,1519,417,978,614,370,2214,441,2151,2465,1022,1458,1407,1232,1676,1101,2406,11,1431,1555,1353,2341,354,530,941,105,15,371,451,615,2418,2298,189,2197,13,1234,733,2174,1614,1082,133,2589,1876,1024,457,1936,1712,1904,34,84,2434,2508,1460,1765,1327,117,701,1713,594,2642,983,1525,1410,1201,2375,469,242,1463,1680,90,1235,1526,2156,2376,756,271,2178,1821,1493,1274,2094,985,573,904,658,2536,1006,1794,823,1412,1905,841,1563,248,1823,23,1594,1766,1940,2238,1854,825,907,1278,2115,1564,2567,1159,453,1103,1909,1437,1494,827,566,788,1133,1084,532,2493,2038,2546,214,156,880,1748,1389,1596,541,1769,1028,1010,372,366,2138,1064,43,1415,488,477,845,607,2290,1944,2616,1043,760,2637,124,695,1721,1044,2222,830,100,2657,37,642,542,1443,97,1,1751,2699,1532,557,684,2664,1472,713,1260,61,1046,1946,238,132,72,79,738,567,2482,521,1660,152,291,739,1984,1913,258,2292,313,1475,1091,492,1501,544,928,761,1394,2012,1395,929,2604,705,1284,833,374,434,82,621,777,485,1370,804,2427,279,1047,1093,2362,1779,331,1503,847,779,559,780,669,2047,707,2,5,792,633,781,303,16,146,1372,202,413,393,752,1050,634,1000,435,1698,609,1169,740,1784,2294,1840,1448,31,494,270,1215,177,1578,1244,53,198,1507,153,191,358,873,1629,1700,896,1245,69,538,1666,1070,1605,0,1013,2143,2351,1288,2102,851,427,2051,375,486,428,59,1867,1581,1513,144,87,674,1217,2402,2485,420,1893,1144,2570,1376,2250,1926,1344,810,1001,951,437,62,1805,2577,394,1119,130,1264,1016,2680,41,1545,317,400,561,1634,1704,1075,414,226,936,2549,509,1265,498,304,953
|
1.1855852561088989,0.4560011507642696,2.7381629713773825,-0.4285902586631195,-0.8349780072652183,-0.4456774203599463,-0.6370462182791121,-2.830790652033712,-0.566722147958878,0.9478015835630615,0.41186430071853863,0.09320779573109034,1.9726052400824703,-0.29367816551779385,-0.7803189764195482,0.23190917857868676,0.35249256146592,-1.0589605873257606,-0.3271128392759249,0.9612662003264605,1.3892066414158972,0.3673920803157548,0.014701291299391921,-0.3945665116133365,2.472830381816948,-0.5492740993843713,1.014819277244463,0.07759089922445578,0.8936333486288025,-0.017000063987738737,2.886090180376803,-0.032915728384741015,-0.243884846085324,-0.7261736594651729,-0.36074150382824394,-1.331826169509489,0.5720990698697436,-0.4285902586631195,0.6435101106197167,3.1993280187186217,-0.4800038669191164,0.7140629338857863,0.5288313967073893,-0.514535240785251,2.3249577453845984,0.9747001337238531,1.1726232359899564,0.10878295888408213,0.04623097246479662,-0.5842230489234069,0.382253743928895,-0.243884846085324,1.0678905729851498,-0.12933524422973913,-0.14556179771058245,-1.0971550435827746,-0.31037139890127774,1.1073832487263275,-0.377629316099032,0.6576886443457405,-0.9272458982666049,-0.14556179771058245,-0.31037139890127774,-0.26043517265107846,0.13980900706892938,-0.5318785727630885,1.586065401491409,-0.1618337970909173,-0.6903572636353332,0.24711890736266962,0.8800131050184969,-0.26043517265107846,0.32257915315367963,0.5143375851029162,-0.4115533912456994,1.8811746612706568,0.9207797152191141,-0.09701742595051951,0.9207797152191141,-0.5842230489234069,0.014701291299391921,-0.8717077957387307,0.1552603482535626,-0.032915728384741015,0.9478015835630615,-0.514535240785251,0.24711890736266962,0.9072221686279333,0.2622891279230963,0.9747001337238531,-0.9272458982666049,0.6435101106197167,0.5864509778300103,-0.09701742595051951,0.2013703373493341,1.4017035243632918,2.5762697271805473,0.030487470396744938,-0.08092564237043719,0.13980900706892938,0.17067086843316673,-0.26043517265107846,0.8114351982042777,0.09320779573109034,0.48524197874422104,0.9072221686279333,-0.6903572636353332,0.7699015142883784,-0.6370462182791121,-0.9645715603540274,0.061932036437784624,-0.22738159228350283,-0.19451519653859392,-0.08092564237043719,-0.3439027766845685,-0.001127805810301048,-0.8901609796463711,3.541068752096914,-0.21092513401942328,-0.27703285170862874,-0.1618337970909173,-0.8167006259673601,0.9478015835630615,0.6007678594820233,0.12431661965225804,2.096080199744481,3.4883696583674233,0.9072221686279333,0.7559915142019157,0.48524197874422104,-0.9086735477231258,-0.7622139544215649,1.549648138953408,-0.6725321288961622,3.497184563628806,-0.08092564237043719,0.32257915315367963,-0.6547618971329058,-0.31037139890127774,0.014701291299391921,1.9384826617323367,-1.2328753903719607,-0.462815185693309,0.061932036437784624,0.7420485262435965,-0.4972437792285436,-0.36074150382824394,-0.4800038669191164,2.953902538225382,2.3249577453845984,-0.9272458982666049,-1.0399582580540272,-0.22738159228350283,-0.3945665116133365,-0.14556179771058245,2.0065339889232616,0.3673920803157548,-0.36074150382824394,0.5143375851029162,-1.5143718566673,0.09320779573109034,-0.26043517265107846,-0.19451519653859392,-0.0648782670729416,-0.8533136017184143,0.7140629338857863,1.3136668502909221,-0.22738159228350283,-0.3439027766845685,2.282030613119506,-0.08092564237043719,-0.26043517265107846,-0.6370462182791121,-0.8533136017184143,0.2925118928589216,1.211424359795403,-0.6547618971329058,-0.4285902586631195,-0.243884846085324,-0.11315387381905866,-0.5842230489234069,0.09320779573109034,0.5432894598416556,0.1552603482535626,0.42661358757948437,-1.0971550435827746,0.07759089922445578,-0.4115533912456994,0.23190917857868676,-0.19451519653859392,-0.4800038669191164,0.21665972726603153,-0.27703285170862874,1.3009827009421377,-0.4285902586631195,3.106106395795426,-0.29367816551779385,-0.3945665116133365,-0.4972437792285436,-0.7082376548394596,-0.4456774203599463,0.23190917857868676,0.1552603482535626,-0.11315387381905866,-0.6017771358819511,-0.27703285170862874,-1.174315546728808,-0.032915728384741015,0.7559915142019157,-0.001127805810301048,-0.4800038669191164,-0.21092513401942328,-0.243884846085324,0.23190917857868676,0.5577119571515898,0.2622891279230963,-0.017000063987738737,0.014701291299391921,0.6007678594820233,-1.0021412347204408,-0.5492740993843713,-1.1163480492502467,1.4141741225146764,1.7883210270224281,0.18604079096340007,-0.377629316099032,-0.17815150752877743,-0.29367816551779385,0.5864509778300103,-0.3945665116133365,0.061932036437784624,0.07759089922445578,0.9072221686279333,0.9207797152191141,-0.6193847456466299,0.030487470396744938,2.7878758792557337,-0.19451519653859392,0.6718330237408522,0.700019999999374,0.21665972726603153,0.4998078409542412,-0.7441656379825385,-0.4972437792285436,-1.3518233822249164,0.04623097246479662,0.2925118928589216,-1.4732988595445302,1.983936246561302,0.382253743928895,-0.36074150382824394,0.04623097246479662,-0.6903572636353332,0.23190917857868676,2.1733484536781895,-1.6183674545716196,2.886090180376803,0.4560011507642696,0.5864509778300103,-0.21092513401942328,2.217058138603211,4.343126506682812,-0.377629316099032,-6.654610001715843,-0.26043517265107846,0.5720990698697436,0.39707775152061925,-1.7029527383730034,-0.22738159228350283,0.35249256146592,-0.09701742595051951,2.4832547399290448,0.04623097246479662,-0.4972437792285436,1.3263238911225568,1.94987853311504,2.420435656490256,2.3463066784162883,0.32257915315367963,0.5577119571515898,-0.983325689072196,0.6150498919054735,-0.3271128392759249,1.8349285964616746,1.1596327314267856,0.32257915315367963,-0.514535240785251,-0.4800038669191164,1.275532592400303,-0.7441656379825385,1.0678905729851498,-0.22738159228350283,0.014701291299391921,0.6718330237408522,-0.243884846085324,0.5864509778300103,0.13980900706892938,0.2925118928589216,-0.17815150752877743,-0.5318785727630885,-0.17815150752877743,0.13980900706892938,-1.2920402919692853,0.3673920803157548,-0.11315387381905866,0.23190917857868676,0.9072221686279333,0.7837786881907414,2.3356417057869807,0.48524197874422104,0.2774200528143013,0.6859434192423728,-0.1618337970909173,0.24711890736266962,-0.9086735477231258,1.1985189212016558,0.04623097246479662,0.014701291299391921,-0.8349780072652183,-0.3945665116133365,1.0014765288625636,-0.243884846085324,0.21665972726603153,0.2774200528143013,0.5720990698697436,0.2774200528143013,0.41186430071853863,-0.5492740993843713,0.3673920803157548,4.084595663215114,4.00405433878558,0.2622891279230963,0.4706398114973275,0.2774200528143013,1.1073832487263275,3.4352105279543297,1.8696467178692489,-0.1618337970909173,1.4761368247888418,0.8252148517366122,0.8800131050184969,0.30756485716682186,0.04623097246479662,0.4706398114973275,0.09320779573109034,0.7837786881907414,-0.3439027766845685,0.4998078409542412,-0.032915728384741015,0.32257915315367963,-0.3945665116133365,-0.7441656379825385,-0.4285902586631195,-0.21092513401942328,2.9827338068802134,0.6718330237408522,1.224301699534718,-0.0648782670729416,1.6462693525823706,-0.27703285170862874,-0.08092564237043719,2.5967459172501477,1.4884520937953238,-0.243884846085324,1.8349285964616746,1.5374592754176952,0.9478015835630615,0.2013703373493341,-0.31037139890127774,-0.3439027766845685,0.17067086843316673,-0.08092564237043719,2.4309512128450095,0.6007678594820233,-0.3271128392759249,0.030487470396744938,-0.29367816551779385,4.48719359410752,0.07759089922445578,-0.6193847456466299,-0.8167006259673601,-0.11315387381905866,-0.5842230489234069,0.21665972726603153,0.7976231963964028,-0.5492740993843713,0.9072221686279333,0.6859434192423728,0.7976231963964028,2.5351071762344404,-0.4456774203599463,-0.27703285170862874,-0.243884846085324,1.8811746612706568,2.303532579472338,0.41186430071853863,-0.0648782670729416,-0.8717077957387307,-0.983325689072196,0.8114351982042777,-0.462815185693309,-0.017000063987738737,-1.174315546728808,-0.1618337970909173,-0.7082376548394596,-0.4800038669191164,-0.14556179771058245,0.24711890736266962,0.09320779573109034,0.12431661965225804,0.7837786881907414,2.4832547399290448,-0.4115533912456994,-1.19376905904756,0.8800131050184969,-0.001127805810301048,1.9612526973306057,-0.09701742595051951,0.07759089922445578,-2.0544746211034344,2.8371826720644844,-0.26043517265107846,1.0546674241385827,0.8663612864956289,0.5720990698697436,-0.31037139890127774,-0.3439027766845685,0.030487470396744938,0.8252148517366122,1.3766833583434828,0.13980900706892938,-1.1163480492502467,0.6435101106197167,-0.09701742595051951,0.6718330237408522,1.1073832487263275,0.12431661965225804
| 2,702
|
Lytic vacuole organization
| 8
| 18
| 3.216139
| 0.001299
|
P07686,P50897,O75503,P11117,P54802,O14773,P04062,Q14108
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,3,206,113,50,150,188,29
|
2148,150,206,188,160,220,113,604,3,1410,50,1905,827,29,1281,780,486,1016
|
-0.6370462182791121,1.8349285964616746,1.4514293500729303,1.549648138953408,1.7531245573462935,1.3892066414158972,2.040271181152975,0.4998078409542412,4.03639791939681,-0.19451519653859392,2.6577600342457113,-0.4800038669191164,0.23190917857868676,3.0018786097104724,-0.11315387381905866,0.2774200528143013,0.6859434192423728,0.07759089922445578
| 2,702
|
Abnormal circulating lipid concentration
| 30
| 69
| 3.207615
| 0.001338
|
Q03252,P07602,P38571,P22830,Q9Y4P3,O75844,O95470,P09622,O75880,P37268,P40855,Q9UJS0,Q15392,Q9NZJ7,O75381,Q14739,Q9NVI7,Q9BV10,O43772,Q9UBM7,P28070,Q8WXH0,P50402,P23786,Q15800,P06280,Q15904,O75431,P02545,P61916
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
391,4,389,7,528,147,275,25,529,154,288,420,166,427,301,175,580,320,83,359,355,506,233,105,367,112,488,499,241,248
|
1548,582,2660,83,301,499,627,147,529,275,241,112,1611,4,25,2611,2195,7,105,355,2028,1156,1061,2392,154,389,288,1739,1740,2436,1327,1359,233,983,2583,1593,2071,2377,658,248,1277,1882,391,1331,1062,828,1257,175,991,166,2043,367,488,1470,2183,1240,506,1284,1538,320,1373,580,427,359,771,420,1956,528,1634
|
-0.27703285170862874,0.5288313967073893,-1.6816883017518833,2.3249577453845984,1.1073832487263275,0.6576886443457405,0.4706398114973275,1.858096452664984,0.6007678594820233,1.1985189212016558,1.3136668502909221,2.040271181152975,-0.31037139890127774,4.00405433878558,3.0399875010519266,-1.331826169509489,-0.6725321288961622,3.7135134684721347,2.096080199744481,0.9478015835630615,-0.5492740993843713,-0.032915728384741015,0.030487470396744938,-0.8717077957387307,1.8233108238857811,0.8800131050184969,1.1726232359899564,-0.377629316099032,-0.377629316099032,-0.9272458982666049,-0.14556179771058245,-0.1618337970909173,1.338953943492325,0.09320779573109034,-1.2132888500172512,-0.29367816551779385,-0.566722147958878,-0.8533136017184143,0.42661358757948437,1.3009827009421377,-0.11315387381905866,-0.462815185693309,0.8800131050184969,-0.14556179771058245,0.030487470396744938,0.23190917857868676,-0.09701742595051951,1.658237345935038,0.09320779573109034,1.705870022831379,-0.5492740993843713,0.9207797152191141,0.6718330237408522,-0.22738159228350283,-0.6547618971329058,-0.08092564237043719,0.6435101106197167,-0.11315387381905866,-0.26043517265107846,1.0414145845970093,-0.1618337970909173,0.5432894598416556,0.7976231963964028,0.9478015835630615,0.2925118928589216,0.8114351982042777,-0.4972437792285436,0.6150498919054735,-0.31037139890127774
| 2,702
|
Protein localization
| 30
| 68
| 3.196959
| 0.001389
|
Q9NS69,Q99595,P21796,Q10713,Q9Y5J9,O15254,P51648,Q13505,P40855,Q9UJS0,Q5JRX3,Q15067,Q9BY49,O75381,Q9Y5J7,P25705,Q8N4H5,Q13011,P09601,Q9NR77,O00116,P46379,O43808,O14925,P06576,O43681,Q9NX63,Q8TB36,P50402,Q15388
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,2,11,397,400,21,277,156,288,420,295,297,299,301,317,451,72,73,334,78,461,84,337,344,215,467,350,484,233,366
|
461,344,688,21,549,467,1148,337,301,2601,499,1734,1812,921,1249,1225,592,785,215,1230,1736,334,2133,978,614,1300,11,1353,451,615,2392,2318,288,84,233,983,277,1593,2536,1331,397,73,532,156,297,366,1043,295,2699,72,714,484,1536,2,2414,634,299,1374,78,0,350,1484,420,1758,1869,663,317,400
|
0.7280723875131836,0.9612662003264605,0.382253743928895,3.162211161281815,0.5720990698697436,0.7140629338857863,-0.032915728384741015,0.9747001337238531,1.1073832487263275,-1.2920402919692853,0.6576886443457405,-0.377629316099032,-0.4285902586631195,0.13980900706892938,-0.09701742595051951,-0.08092564237043719,0.5143375851029162,0.2622891279230963,1.4017035243632918,-0.08092564237043719,-0.377629316099032,0.9881035286247505,-0.6193847456466299,0.09320779573109034,0.48524197874422104,-0.12933524422973913,3.541068752096914,-0.1618337970909173,0.7559915142019157,0.48524197874422104,-0.8717077957387307,-0.7803189764195482,1.1726232359899564,2.3249577453845984,1.338953943492325,0.09320779573109034,1.1985189212016558,-0.29367816551779385,-1.0971550435827746,-0.14556179771058245,0.8663612864956289,2.40990166122177,0.6007678594820233,1.7883210270224281,1.1204890033550043,0.9207797152191141,0.04623097246479662,1.1466136121023172,-6.654610001715843,2.420435656490256,0.35249256146592,0.6859434192423728,-0.26043517265107846,4.084595663215114,-0.8901609796463711,0.4706398114973275,1.1204890033550043,-0.1618337970909173,2.3569527332268905,4.48719359410752,0.9612662003264605,-0.22738159228350283,0.8114351982042777,-0.377629316099032,-0.4456774203599463,0.42661358757948437,1.0546674241385827,0.8663612864956289
| 2,702
|
Alpha/Beta hydrolase fold [IPR029058]
| 7
| 21
| 3.195237
| 0.001397
|
Q4J6C6,P50897,Q9HB40,P10619,Q9H6V9,P42785,Q9H3G5
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
66,3,6,38,8,12,18
|
1991,2256,70,38,2564,2340,389,12,1434,1182,3,66,1134,425,643,18,8,6,333,2401,813
|
-0.5318785727630885,-0.7261736594651729,2.420435656490256,2.8665746612984697,-1.174315546728808,-0.8167006259673601,0.8800131050184969,3.523552992410392,-0.21092513401942328,-0.04887504627384466,4.03639791939681,2.441448397195739,-0.017000063987738737,0.7976231963964028,0.4560011507642696,3.2820201142446788,3.627900422577668,3.9059864908023467,1.0014765288625636,-0.8717077957387307,0.24711890736266962
| 2,702
|
Side of membrane
| 21
| 62
| 3.195132
| 0.001398
|
O15439,P11279,Q9H0H5,O96005,Q9NR28,P00813,Q9Y5X3,P17900,P10619,P10321,O75955,P08183,P42892,P31749,Q9H2H9,P41440,Q8TCT9,P51572,P35579,P51790,Q8TCT8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
380,387,270,145,410,27,414,162,38,423,422,54,55,189,198,457,77,469,345,242,118
|
636,1958,380,422,145,1227,27,665,818,2487,1994,957,718,54,1380,2132,423,38,1589,387,2062,1300,1060,923,162,819,1022,1232,980,1998,1408,1326,189,345,1522,457,55,1272,1182,469,242,2420,1939,865,2422,1202,2159,2285,1824,1335,483,118,77,2184,1372,270,198,410,1072,2570,1075,414
|
0.4560011507642696,-0.514535240785251,0.8936333486288025,0.7976231963964028,1.8696467178692489,-0.08092564237043719,3.0018786097104724,0.41186430071853863,0.23190917857868676,-1.0021412347204408,-0.5318785727630885,0.10878295888408213,0.3375549865593367,2.5762697271805473,-0.17815150752877743,-0.6193847456466299,0.7976231963964028,2.8665746612984697,-0.29367816551779385,0.8800131050184969,-0.566722147958878,-0.12933524422973913,0.030487470396744938,0.13980900706892938,1.7295441678744543,0.23190917857868676,0.061932036437784624,-0.08092564237043719,0.09320779573109034,-0.5318785727630885,-0.19451519653859392,-0.14556179771058245,1.549648138953408,0.9612662003264605,-0.26043517265107846,0.7420485262435965,2.5660054539144865,-0.11315387381905866,-0.04887504627384466,0.7140629338857863,1.3136668502909221,-0.9086735477231258,-0.4972437792285436,0.2013703373493341,-0.9086735477231258,-0.0648782670729416,-0.6370462182791121,-0.7441656379825385,-0.4285902586631195,-0.14556179771058245,0.6859434192423728,2.0065339889232616,2.3569527332268905,-0.6547618971329058,-0.1618337970909173,1.224301699534718,1.4884520937953238,0.8389623139505717,0.030487470396744938,-1.174315546728808,0.030487470396744938,0.8252148517366122
| 2,702
|
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