term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Mitochondrial membrane organization
16
43
3.155721
0.001601
Q9NS69,Q15070,Q9P0J0,Q13505,Q9H3K2,Q9BUR5,Q9Y512,O60313,Q9NX63,O95202,O14737,P05141,P17152,P45880,Q9NVH1,Q9Y5J7
Processes and pathways
GO Biological process
msigdb_gobp
0,167,171,46,303,340,343,239,311,332,242,274,276,26,355,254
512,242,239,700,758,332,1843,274,1196,1118,794,276,2524,1440,1886,2211,2102,26,762,1202,46,167,2526,568,1013,869,718,944,373,1017,2149,665,340,303,0,355,311,171,1065,820,343,254,650
0.5646389006836805,1.1140084276296076,1.1310694730368478,0.3467667149096307,0.3011488166696212,0.8438063884694104,-0.36473682773465654,1.0092219778652174,0.011651732815977752,0.06187795047934465,0.27807073501123514,1.0092219778652174,-1.1321541889327764,-0.1176342396375531,-0.3934145562501481,-0.6324042683431318,-0.540732380985242,3.2819030749164693,0.3011488166696212,0.011651732815977752,2.753410498029949,1.538436752547887,-1.1321541889327764,0.5010015722710037,0.13569066148578596,0.2313650943574053,0.3467667149096307,0.18391141717841533,0.7863246738934979,0.13569066148578596,-0.5710083209352036,0.39168144268614885,0.8438063884694104,0.9369680850132093,4.4345567444728164,0.8247808034059452,0.9185931557162074,1.509380323825773,0.1112864967658255,0.27807073501123514,0.8438063884694104,1.0795454359625347,0.4138804266239855
2,702
Mitochondrial substrate/solute carrier [IPR018108]
12
18
3.143701
0.001668
P05141,Q9UBX3,Q9NZJ7,P12236,Q9BQT8,Q70HW3,Q9Y6C9,O43772,Q6NUK1,O43808,Q9H2D1,Q9HC21
Sequence
InterPro Repeat
interpro_repeat
274,103,365,267,120,14,273,56,414,283,60,323
56,283,594,274,794,267,933,835,414,14,120,60,323,365,103,429,885,273
2.5187525853416863,0.9913427102790784,0.45777194879673416,1.0092219778652174,0.27807073501123514,1.044619903415622,0.18391141717841533,0.254810254426627,0.7077496739843829,3.4216157303597954,1.8743612216621832,2.4814715373825837,0.881460002398148,0.8056207329272186,2.088833108363494,0.687750303214672,0.2313650943574053,1.026980616676179
2,702
Mitochondrial carrier domain superfamily [IPR023395]
12
18
3.143701
0.001668
P05141,Q9UBX3,Q9NZJ7,P12236,Q9BQT8,Q70HW3,Q9Y6C9,O43772,Q6NUK1,O43808,Q9H2D1,Q9HC21
Sequence
InterPro Superfamily
interpro_homologous_superfamily
274,103,365,267,120,14,273,56,414,283,60,323
56,283,594,274,794,267,933,835,414,14,120,60,323,365,103,429,885,273
2.5187525853416863,0.9913427102790784,0.45777194879673416,1.0092219778652174,0.27807073501123514,1.044619903415622,0.18391141717841533,0.254810254426627,0.7077496739843829,3.4216157303597954,1.8743612216621832,2.4814715373825837,0.881460002398148,0.8056207329272186,2.088833108363494,0.687750303214672,0.2313650943574053,1.026980616676179
2,702
SLC25 family of mitochondrial transporters
12
18
3.143701
0.001668
P05141,Q9UBX3,Q9NZJ7,P12236,Q9BQT8,Q70HW3,Q9Y6C9,O43772,Q6NUK1,O43808,Q9H2D1,Q9HC21
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
274,103,365,267,120,14,273,56,414,283,60,323
56,283,594,274,794,267,933,835,414,14,120,60,323,365,103,429,885,273
2.5187525853416863,0.9913427102790784,0.45777194879673416,1.0092219778652174,0.27807073501123514,1.044619903415622,0.18391141717841533,0.254810254426627,0.7077496739843829,3.4216157303597954,1.8743612216621832,2.4814715373825837,0.881460002398148,0.8056207329272186,2.088833108363494,0.687750303214672,0.2313650943574053,1.026980616676179
2,702
Intrinsic component of mitochondrial inner membrane
13
30
3.137475
0.001704
Q99595,Q15070,Q6P4A7,Q9Y2R0,Q13505,Q9H3K2,O14925,Q9BUR5,Q9Y512,Q9NX63,P17152,Q9NVH1,Q9HC21
Localization
GO Cellular component
msigdb_gocc
1,167,41,77,46,303,206,340,343,311,276,355,323
206,700,917,1112,276,2211,933,46,167,362,568,869,718,41,944,691,2544,473,1,340,303,1181,1096,323,355,311,591,77,820,343
1.2797111548412214,0.3467667149096307,0.18391141717841533,0.06187795047934465,1.0092219778652174,-0.6324042683431318,0.18391141717841533,2.753410498029949,1.538436752547887,0.8056207329272186,0.5010015722710037,0.2313650943574053,0.3467667149096307,2.8568664927325975,0.18391141717841533,0.36931090448637094,-1.1681714201941449,0.6268724257185203,4.159262994962356,0.8438063884694104,0.9369680850132093,0.036868377335003144,0.08668311743058034,0.881460002398148,0.8247808034059452,0.9185931557162074,0.47946851200506696,2.3452866902285905,0.27807073501123514,0.8438063884694104
2,702
Carbohydrate derivative catabolic process
13
31
3.123459
0.001787
P08236,P00813,P15586,Q13126,P36639,P54802,P49902,P06865,P17900,P16278,O60502,P06280,P04062
Processes and pathways
GO Biological process
msigdb_gobp
261,225,164,4,105,141,45,177,113,19,54,215,125
1585,54,2319,1239,225,125,1114,215,177,919,261,164,19,113,2239,1037,105,1598,45,141,932,4,2571,1020,984,281,2610,1062,881,2679,455
-0.19787205833249796,2.582356770154656,-0.7586901436735312,-0.01377469592003253,1.1815848149569044,1.8365297753474792,0.06187795047934465,1.247422490494699,1.435179083173316,0.18391141717841533,1.0621410964140288,1.5528345987170111,3.3763606176597847,1.9115709631930478,-0.6635325569459647,0.1112864967658255,2.0774498833224193,-0.19787205833249796,2.7697034335726243,1.678647365092368,0.18391141717841533,3.929611495114198,-1.2784570650664284,0.13569066148578596,0.15989814001547026,1.0092219778652174,-1.470087388879226,0.1112864967658255,0.2313650943574053,-2.6593876171916686,0.6473133664185765
2,702
Endopeptidase activity
25
59
3.119324
0.001813
Q16740,P28072,Q9NZ08,P49768,P49721,P07384,P20618,Q99436,Q5JRX3,P60900,O75844,P28074,P67812,P52888,Q86UV5,O14773,P28070,Q9BYT8,Q92643,Q92542,P42892,Q99797,Q8TCT9,Q8TCT8,Q9UPU5
Functions
GO Molecular function
msigdb_gomf
128,129,137,397,20,42,295,442,182,436,57,433,72,73,337,199,207,92,220,222,95,108,244,115,121
199,561,2600,57,42,1591,2413,295,1487,1847,207,129,433,2010,1850,2701,2012,1401,95,1723,2469,1814,20,397,73,2136,2300,436,72,1129,1085,453,2141,1414,128,2110,182,1895,555,337,115,244,222,220,1139,1791,1660,746,1945,1268,442,1830,108,1374,92,137,509,121,820
1.3115908775571128,0.5010015722710037,-1.4309487853394973,2.5094973738711897,2.849109236264797,-0.19787205833249796,-0.8898717216903321,0.9552170880450557,-0.14415202790824028,-0.36473682773465654,1.2797111548412214,1.7850921167036022,0.6676054254045067,-0.4810044712723359,-0.36473682773465654,-7.296535538848486,-0.4810044712723359,-0.09134055376869563,2.1337776504182426,-0.2802102847132027,-0.9916536280362304,-0.33631253477906203,3.3590589468435246,0.7276051859633127,2.3949755597742,-0.5710083209352036,-0.7266710972825526,0.6676054254045067,2.404770322309479,0.06187795047934465,0.08668311743058034,0.6473133664185765,-0.5710083209352036,-0.09134055376869563,1.7980601075871823,-0.540732380985242,1.404856290131458,-0.3934145562501481,0.5223730615720535,0.8438063884694104,1.9115709631930478,1.1140084276296076,1.1982044600111101,1.2147165622569294,0.06187795047934465,-0.308138168176809,-0.22508051495738804,0.3240467416918007,-0.4223492971351874,-0.01377469592003253,0.6676054254045067,-0.33631253477906203,1.9960644529824567,-0.06526800225829026,2.1559035701841203,1.7191369886638892,0.5855369618145146,1.8743612216621832,0.27807073501123514
2,702
Endomembrane system organization
55
144
3.085573
0.002032
Q8N1F7,P40616,O95721,P63104,O15260,Q96CP7,Q12846,P42858,Q15629,Q9UQB8,Q14108,O95197,P31749,Q9P0I2,Q15363,Q5J8M3,P46379,O75844,Q00765,O14976,Q7Z7H5,O43760,Q13190,Q9H8Y8,Q8IYI6,Q9Y3B3,P51790,O00429,P06493,Q96A33,A0FGR8,O14578,Q9BVK6,Q9Y2J2,Q8N4V1,P61619,Q9NP72,P48729,O14964,Q9NQC3,Q9BTU6,Q12907,Q6P1A2,Q8WUX9,Q9UH99,Q14789,Q86XL3,Q14203,P16615,Q9P2W9,P50402,O75955,P57088,P49755,O43765
Processes and pathways
GO Biological process
msigdb_gobp
389,386,384,519,140,280,536,532,29,31,30,33,409,558,37,426,168,57,566,560,191,65,452,588,586,68,198,447,578,330,576,577,205,478,79,580,607,460,331,88,217,221,227,507,633,628,107,486,369,116,243,614,248,378,499
576,1708,447,577,2197,912,331,560,1632,140,1586,1035,1336,1337,65,499,1284,1338,1766,1287,1340,2495,1341,57,614,1073,33,1712,384,1036,578,1920,369,2205,998,853,2172,2498,409,735,1646,386,856,532,2269,168,1852,460,1648,378,243,762,1163,1078,198,926,1255,248,1500,686,2595,580,739,519,566,710,1082,2220,536,221,1567,1933,1507,452,30,486,628,2651,1362,37,29,1364,426,1260,1460,773,227,2680,1053,2251,1463,191,107,1939,586,389,79,1138,1523,1264,663,664,507,905,647,805,330,280,1222,1375,1270,217,813,205,2117,1579,588,607,1272,88,1186,1381,558,1472,2408,116,633,1704,951,2292,1959,2165,910,725,31,478,2611,884,1032,1331,68,1385,2447,958
0.47946851200506696,-0.2802102847132027,0.6473133664185765,0.47946851200506696,-0.6324042683431318,0.18391141717841533,0.8438063884694104,0.5010015722710037,-0.22508051495738804,1.692221906453172,-0.19787205833249796,0.1112864967658255,-0.06526800225829026,-0.06526800225829026,2.4434845439398956,0.5855369618145146,-0.03941367046144973,-0.06526800225829026,-0.308138168176809,-0.03941367046144973,-0.06526800225829026,-1.0612014774574168,-0.06526800225829026,2.5094973738711897,0.4359099189969065,0.08668311743058034,3.082238226873909,-0.2802102847132027,0.74731846202068,0.1112864967658255,0.47946851200506696,-0.4223492971351874,0.7863246738934979,-0.6324042683431318,0.13569066148578596,0.2313650943574053,-0.6015642502581877,-1.0612014774574168,0.7077496739843829,0.3240467416918007,-0.22508051495738804,0.74731846202068,0.2313650943574053,0.5435848808587928,-0.6949533822984102,1.5239522688610696,-0.36473682773465654,0.6268724257185203,-0.22508051495738804,0.7668911001385372,1.1140084276296076,0.3011488166696212,0.036868377335003144,0.08668311743058034,1.3273799247937976,0.18391141717841533,-0.01377469592003253,1.0968341446394454,-0.14415202790824028,0.36931090448637094,-1.392223197306997,0.47946851200506696,0.3240467416918007,0.5646389006836805,0.5010015722710037,0.3467667149096307,0.08668311743058034,-0.6324042683431318,0.5435848808587928,1.1982044600111101,-0.17089694126863775,-0.4223492971351874,-0.14415202790824028,0.6473133664185765,3.1093432588488037,0.6062808758329494,0.4359099189969065,-2.0198857548091578,-0.06526800225829026,2.9694470635904917,3.1293985059553213,-0.06526800225829026,0.687750303214672,-0.01377469592003253,-0.1176342396375531,0.3011488166696212,1.1815848149569044,-3.0494230058693037,0.1112864967658255,-0.6635325569459647,-0.1176342396375531,1.3741556701287698,2.0078769667953464,-0.4223492971351874,0.47946851200506696,0.74731846202068,2.3250705886421623,0.06187795047934465,-0.14415202790824028,-0.01377469592003253,0.39168144268614885,0.39168144268614885,0.5855369618145146,0.20773293514525631,0.4138804266239855,0.27807073501123514,0.8626989686693847,1.0092219778652174,0.011651732815977752,-0.06526800225829026,-0.01377469592003253,1.247422490494699,0.27807073501123514,1.2957016226393265,-0.540732380985242,-0.17089694126863775,0.47946851200506696,0.45777194879673416,-0.01377469592003253,2.188669927046933,0.036868377335003144,-0.06526800225829026,0.5223730615720535,-0.1176342396375531,-0.8566010715319217,1.8992357988485726,0.4359099189969065,-0.25252550560044684,0.18391141717841533,-0.6949533822984102,-0.4223492971351874,-0.5710083209352036,0.20773293514525631,0.3467667149096307,3.1093432588488037,0.6268724257185203,-1.470087388879226,0.2313650943574053,0.13569066148578596,-0.03941367046144973,2.424219700870432,-0.06526800225829026,-0.9234673291200788,0.18391141717841533
2,702
Intra golgi and retrograde golgi to er traffic
25
78
3.072851
0.00212
Q13561,P40616,P24390,O95721,O15260,Q9H0H5,Q16706,Q6NUQ1,Q15363,O75935,P04350,P20645,Q13190,Q9Y3B3,O95249,Q9BVK6,P11717,O00461,P68371,Q14203,Q9P2W9,Q8N2H4,Q9BVA1,P49755,Q9Y678
Processes and pathways
Reactome Pathways
msigdb_reactome
387,386,7,384,140,145,278,160,37,418,300,175,452,68,200,205,457,90,464,486,116,117,380,378,393
1539,90,1916,140,1335,914,1586,730,1340,418,1394,993,200,384,300,457,920,175,7,1348,1442,386,2269,1852,2271,1161,1445,378,1405,1002,1601,1602,1727,1974,1165,623,739,464,797,1206,1043,1084,2180,1933,452,2420,387,599,486,798,2064,1512,37,278,836,160,1615,2253,117,2030,874,905,2363,908,670,380,205,2517,145,607,2602,116,1426,510,68,1104,393,1387
-0.17089694126863775,2.1559035701841203,-0.4223492971351874,1.692221906453172,-0.06526800225829026,0.18391141717841533,-0.19787205833249796,0.3240467416918007,-0.06526800225829026,0.687750303214672,-0.09134055376869563,0.13569066148578596,1.3115908775571128,0.74731846202068,0.9369680850132093,0.6268724257185203,0.18391141717841533,1.4651313202975424,3.630300382746048,-0.06526800225829026,-0.1176342396375531,0.74731846202068,-0.6949533822984102,-0.36473682773465654,-0.6949533822984102,0.036868377335003144,-0.1176342396375531,0.7668911001385372,-0.09134055376869563,0.13569066148578596,-0.19787205833249796,-0.19787205833249796,-0.2802102847132027,-0.4515446964616516,0.036868377335003144,0.4359099189969065,0.3240467416918007,0.6268724257185203,0.27807073501123514,0.011651732815977752,0.1112864967658255,0.08668311743058034,-0.6015642502581877,-0.4223492971351874,0.6473133664185765,-0.8898717216903321,0.74731846202068,0.45777194879673416,0.6062808758329494,0.27807073501123514,-0.5107324113409443,-0.14415202790824028,2.9694470635904917,1.0092219778652174,0.254810254426627,1.581373621216261,-0.19787205833249796,-0.6635325569459647,1.8743612216621832,-0.4810044712723359,0.2313650943574053,0.20773293514525631,-0.7910150544529415,0.20773293514525631,0.39168144268614885,0.7668911001385372,1.2957016226393265,-1.0964994453628252,1.6649938710643004,0.45777194879673416,-1.4309487853394973,1.8992357988485726,-0.09134055376869563,0.5855369618145146,2.424219700870432,0.08668311743058034,0.74731846202068,-0.06526800225829026
2,702
Slc mediated transmembrane transport
10
22
3.068224
0.002153
Q9UBX3,P12236,Q8NEW0,Q70HW3,Q9H2H9,Q8TB61,Q9Y289,P05141,O00400,P35613
Processes and pathways
Reactome Pathways
msigdb_reactome
103,267,109,14,210,181,184,274,155,159
155,514,274,1435,1882,794,267,1294,159,1159,1498,940,2025,14,109,181,492,557,210,103,184,305
1.5955163931080725,0.5646389006836805,1.0092219778652174,-0.1176342396375531,-0.3934145562501481,0.27807073501123514,1.044619903415622,-0.03941367046144973,1.581373621216261,0.036868377335003144,-0.14415202790824028,0.18391141717841533,-0.4810044712723359,3.4216157303597954,1.9602443238318379,1.4200644560622815,0.6062808758329494,0.5223730615720535,1.2797111548412214,2.088833108363494,1.404856290131458,0.9369680850132093
2,702
Active ion transmembrane transporter activity
21
43
3.056897
0.002236
Q9HD20,P04920,P12236,P13073,P05141,O00400,P00403,P21281,Q9Y6M7,Q9Y289,Q7KZN9,P51790,Q96ES6,Q9H2H9,O95202,P61421,Q9UDW1,Q9Y5K8,Q96QD8,P16615,O15439
Functions
GO Molecular function
msigdb_gomf
136,514,267,269,274,155,407,291,305,184,195,198,76,210,332,463,98,229,492,369,479
155,479,332,407,514,615,1674,274,1115,1435,893,1639,794,267,269,369,531,1249,291,2127,680,2468,2558,922,1721,856,198,1683,463,1932,933,835,195,76,492,779,210,136,98,1799,184,229,305
1.5955163931080725,0.6062808758329494,0.8438063884694104,0.7077496739843829,0.5646389006836805,0.4359099189969065,-0.25252550560044684,1.0092219778652174,0.06187795047934465,-0.1176342396375531,0.20773293514525631,-0.22508051495738804,0.27807073501123514,1.044619903415622,1.026980616676179,0.7863246738934979,0.5435848808587928,-0.01377469592003253,0.9733415184995973,-0.5710083209352036,0.36931090448637094,-0.9916536280362304,-1.241316825230039,0.18391141717841533,-0.2802102847132027,0.2313650943574053,1.3273799247937976,-0.25252550560044684,0.6268724257185203,-0.4223492971351874,0.18391141717841533,0.254810254426627,1.3430697559709033,2.3452866902285905,0.6062808758329494,0.3011488166696212,1.2797111548412214,1.7191369886638892,2.1337776504182426,-0.308138168176809,1.404856290131458,1.1815848149569044,0.9369680850132093
2,702
Tetrapyrrole binding
8
15
3.044237
0.002333
Q8WUJ1,Q7KZN9,O15173,O43169,Q16850,P30519,P09601,O00264
Functions
GO Molecular function
msigdb_gomf
35,195,70,15,50,51,211,394
394,70,15,893,211,1552,51,50,1315,195,35,2390,841,416,1183
0.7276051859633127,2.404770322309479,3.3991465956104387,0.20773293514525631,1.2636184551493796,-0.17089694126863775,2.703674013197799,2.71205420662372,-0.03941367046144973,1.3430697559709033,3.0196771077390956,-0.8236504561955251,0.254810254426627,0.7077496739843829,0.036868377335003144
2,702
Sphingolipid metabolism
11
24
3.03425
0.002411
Q96G23,O95470,Q13510,Q06136,P07602,P06865,P17900,P16278,P06280,P04062,P10619
Processes and pathways
Reactome Pathways
msigdb_reactome
99,133,134,106,11,177,113,19,215,125,63
576,1541,2687,1337,1712,133,125,215,177,11,919,63,19,113,853,219,106,134,2145,99,1270,1186,365,1472
0.47946851200506696,-0.17089694126863775,-4.022459552775041,-0.06526800225829026,-0.2802102847132027,1.7191369886638892,1.8365297753474792,1.247422490494699,1.435179083173316,3.503168251453378,0.18391141717841533,2.4530486238043636,3.3763606176597847,1.9115709631930478,0.2313650943574053,1.2311222135057562,2.042939361579597,1.7191369886638892,-0.5710083209352036,2.122628808729958,-0.01377469592003253,0.036868377335003144,0.8056207329272186,-0.1176342396375531
2,702
transporter
23
56
3.014078
0.002578
Q99595,Q99805,Q8N1F7,P52292,Q99808,Q567V2,Q15070,Q8NFH4,O15397,Q12769,Q9UJZ1,O95373,O43772,P48739,Q9H2D1,Q6N075,Q9NR77,P61619,P52294,P55060,Q8TEX9,Q92973,Q9HD45
Functions
Panther Protein class
panther_protein_class
1,390,389,398,557,293,167,294,176,308,446,563,56,314,60,583,476,580,461,462,118,375,123
612,1540,2125,2197,1069,176,674,1337,56,1390,1341,563,1121,1925,856,314,2013,398,461,1891,1498,1779,462,763,796,580,308,1259,167,293,583,1213,389,294,2114,118,947,375,776,605,1751,1,390,557,1624,2365,60,2258,1182,123,476,882,2530,446,754,885
0.4359099189969065,-0.17089694126863775,-0.5710083209352036,-0.6324042683431318,0.08668311743058034,1.435179083173316,0.36931090448637094,-0.06526800225829026,2.5187525853416863,-0.09134055376869563,-0.06526800225829026,0.5010015722710037,0.06187795047934465,-0.4223492971351874,0.2313650943574053,0.9000909263071639,-0.4810044712723359,0.7276051859633127,0.6268724257185203,-0.3934145562501481,-0.14415202790824028,-0.308138168176809,0.6268724257185203,0.3011488166696212,0.27807073501123514,0.47946851200506696,0.9185931557162074,-0.01377469592003253,1.538436752547887,0.9733415184995973,0.47946851200506696,0.011651732815977752,0.74731846202068,0.9733415184995973,-0.540732380985242,1.8743612216621832,0.18391141717841533,0.7863246738934979,0.3011488166696212,0.45777194879673416,-0.2802102847132027,4.159262994962356,0.74731846202068,0.5223730615720535,-0.19787205833249796,-0.7910150544529415,2.4814715373825837,-0.6635325569459647,0.036868377335003144,1.849210343127848,0.6268724257185203,0.2313650943574053,-1.1321541889327764,0.6676054254045067,0.3240467416918007,0.2313650943574053
2,702
Hydrolase activity hydrolyzing o glycosyl compounds
10
18
3.011221
0.002602
P08236,P54802,P06865,P17900,Q16706,P16278,Q9BTY2,P06280,O60502,P04062
Functions
GO Molecular function
msigdb_gomf
261,141,177,113,278,19,281,215,54,125
2448,54,125,1114,215,177,919,261,317,19,113,831,141,2138,1860,278,281,881
-0.957392920200188,2.582356770154656,1.8365297753474792,0.06187795047934465,1.247422490494699,1.435179083173316,0.18391141717841533,1.0621410964140288,0.881460002398148,3.3763606176597847,1.9115709631930478,0.254810254426627,1.678647365092368,-0.5710083209352036,-0.36473682773465654,1.0092219778652174,1.0092219778652174,0.2313650943574053
2,702
Intrinsic component of mitochondrial membrane
21
44
2.990389
0.002786
Q99595,P57105,P17152,Q15388,Q15070,Q6P4A7,Q13505,Q9H3K2,Q9NX63,Q16891,Q9HC21,Q9BPX6,Q96NB2,O14925,Q9BUR5,Q9Y2R0,Q9Y512,Q9NVH1,Q8TB36,Q16134,Q8IWA4
Localization
GO Cellular component
msigdb_gocc
1,517,276,413,167,41,46,303,311,568,323,474,473,206,340,77,343,355,352,362,373
206,700,917,758,1112,891,794,276,2211,517,933,46,167,413,362,2526,568,869,718,41,944,373,1017,2149,691,352,2544,473,1,474,842,340,2116,303,1181,1096,323,355,311,591,817,77,820,343
1.2797111548412214,0.3467667149096307,0.18391141717841533,0.3011488166696212,0.06187795047934465,0.20773293514525631,0.27807073501123514,1.0092219778652174,-0.6324042683431318,0.5646389006836805,0.18391141717841533,2.753410498029949,1.538436752547887,0.7077496739843829,0.8056207329272186,-1.1321541889327764,0.5010015722710037,0.2313650943574053,0.3467667149096307,2.8568664927325975,0.18391141717841533,0.7863246738934979,0.13569066148578596,-0.5710083209352036,0.36931090448637094,0.8247808034059452,-1.1681714201941449,0.6268724257185203,4.159262994962356,0.6268724257185203,0.254810254426627,0.8438063884694104,-0.540732380985242,0.9369680850132093,0.036868377335003144,0.08668311743058034,0.881460002398148,0.8247808034059452,0.9185931557162074,0.47946851200506696,0.27807073501123514,2.3452866902285905,0.27807073501123514,0.8438063884694104
2,702
Membrane lipid catabolic process
6
11
2.988088
0.002807
O95470,Q13510,P06865,P17900,P50897,P04062
Processes and pathways
GO Biological process
msigdb_gobp
133,134,177,113,82,125
133,125,1114,215,177,919,113,82,134,811,1186
1.7191369886638892,1.8365297753474792,0.06187795047934465,1.247422490494699,1.435179083173316,0.18391141717841533,1.9115709631930478,2.2632150164335987,1.7191369886638892,0.27807073501123514,0.036868377335003144
2,702
Organic anion transmembrane transporter activity
17
31
2.983979
0.002845
Q9UJS0,Q96QD8,Q9UBX3,P12236,Q96NB2,Q9BQT8,Q9Y6M7,Q9H2H9,O15439,Q8TB61,Q9Y289,P05141,Q6NUK1,O43808,Q9H2D1,O00400,Q9HC21
Functions
GO Molecular function
msigdb_gomf
429,492,103,267,473,120,305,210,479,181,184,274,414,283,60,155,323
155,479,283,594,1112,274,1435,1882,794,267,2558,856,1498,835,940,414,2025,181,473,492,557,120,60,210,1181,323,103,429,184,885,305
1.5955163931080725,0.6062808758329494,0.9913427102790784,0.45777194879673416,0.06187795047934465,1.0092219778652174,-0.1176342396375531,-0.3934145562501481,0.27807073501123514,1.044619903415622,-1.241316825230039,0.2313650943574053,-0.14415202790824028,0.254810254426627,0.18391141717841533,0.7077496739843829,-0.4810044712723359,1.4200644560622815,0.6268724257185203,0.6062808758329494,0.5223730615720535,1.8743612216621832,2.4814715373825837,1.2797111548412214,0.036868377335003144,0.881460002398148,2.088833108363494,0.687750303214672,1.404856290131458,0.2313650943574053,0.9369680850132093
2,702
Steroid binding
12
20
2.949592
0.003182
O15173,O15118,Q9H4L5,P61916,P30536,O00264,P04062,P21796,O75477,P45880,P38435,Q14108
Functions
GO Molecular function
msigdb_gomf
70,74,381,240,114,394,125,23,313,26,156,30
394,74,70,313,2094,125,615,1920,23,853,1772,114,156,26,240,30,2362,1875,428,381
0.7276051859633127,2.3553210205573603,2.404770322309479,0.9000909263071639,-0.540732380985242,1.8365297753474792,0.4359099189969065,-0.4223492971351874,3.300030759770216,0.2313650943574053,-0.308138168176809,1.9115709631930478,1.5955163931080725,3.2819030749164693,1.1310694730368478,3.1093432588488037,-0.7910150544529415,-0.36473682773465654,0.687750303214672,0.7668911001385372
2,702
Calcium-binding protein
7
14
2.945717
0.003222
Q9Y376,Q15293,P80303,O43852,Q14257,P43307,Q02818
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
392,388,9,265,179,53,62
265,1848,734,53,1300,1562,9,62,179,388,1419,1175,474,392
1.044619903415622,-0.36473682773465654,0.3240467416918007,2.6001584197679355,-0.03941367046144973,-0.17089694126863775,3.5552821414043194,2.4625675937937155,1.4200644560622815,0.74731846202068,-0.09134055376869563,0.036868377335003144,0.6268724257185203,0.74731846202068
2,702
Aminoglycan metabolic process
6
13
2.941766
0.003263
P08236,P15586,P54802,O43505,P06865,P16278
Processes and pathways
GO Biological process
msigdb_gobp
261,164,141,78,177,19
78,2091,791,1114,177,919,261,164,19,141,1127,1518,304
2.3250705886421623,-0.540732380985242,0.27807073501123514,0.06187795047934465,1.435179083173316,0.18391141717841533,1.0621410964140288,1.5528345987170111,3.3763606176597847,1.678647365092368,0.06187795047934465,-0.14415202790824028,0.9369680850132093
2,702
Peptide binding
20
61
2.941528
0.003266
O15212,Q99471,P24390,Q9NZ08,P52292,O00264,Q9H7Z7,Q15388,P55786,P10321,Q15392,Q9UIQ6,Q8WTV0,O14773,Q14978,Q9BYT8,P42892,P40855,Q8TEX9,Q92973
Functions
GO Molecular function
msigdb_gomf
257,135,7,137,398,394,416,413,157,419,49,58,69,199,467,92,95,226,118,375
394,612,1540,2125,199,257,2295,1634,1390,758,1548,850,1243,759,419,2413,2621,2487,7,1848,1720,2524,1812,1596,1121,1887,226,95,1724,2013,1162,762,398,461,1891,157,1855,580,1684,2014,1208,974,1259,467,413,49,118,69,375,1266,135,811,1094,92,2565,416,671,137,544,672,58
0.7276051859633127,0.4359099189969065,-0.17089694126863775,-0.5710083209352036,1.3115908775571128,1.0621410964140288,-0.7266710972825526,-0.22508051495738804,-0.09134055376869563,0.3011488166696212,-0.17089694126863775,0.2313650943574053,-0.01377469592003253,0.3011488166696212,0.687750303214672,-0.8898717216903321,-1.54963172247134,-1.0262546953488343,3.630300382746048,-0.36473682773465654,-0.2802102847132027,-1.1321541889327764,-0.33631253477906203,-0.19787205833249796,0.06187795047934465,-0.3934145562501481,1.1815848149569044,2.1337776504182426,-0.2802102847132027,-0.4810044712723359,0.036868377335003144,0.3011488166696212,0.7276051859633127,0.6268724257185203,-0.3934145562501481,1.5955163931080725,-0.36473682773465654,0.47946851200506696,-0.25252550560044684,-0.4810044712723359,0.011651732815977752,0.15989814001547026,-0.01377469592003253,0.6268724257185203,0.7077496739843829,2.71205420662372,1.8743612216621832,2.414518252119156,0.7863246738934979,-0.01377469592003253,1.7191369886638892,0.27807073501123514,0.08668311743058034,2.1559035701841203,-1.241316825230039,0.7077496739843829,0.39168144268614885,1.7191369886638892,0.5435848808587928,0.39168144268614885,2.500199007739095
2,702
Receptor
14
25
2.938395
0.003299
O75381,Q13432,Q13641,Q567V2,Q8WTV0,Q9Y639,Q9NR77,P57105,P20645,Q9BUN8,P11717,A6NIH7,Q9UQB8,Q14108
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
345,5,521,293,69,367,476,517,175,209,457,25,31,30
25,1069,1236,345,1769,791,2201,457,175,517,688,5,521,30,293,555,69,664,209,1182,476,1911,2444,31,367
3.2940101477528185,0.08668311743058034,-0.01377469592003253,0.8247808034059452,-0.308138168176809,0.27807073501123514,-0.6324042683431318,0.6268724257185203,1.4651313202975424,0.5646389006836805,0.36931090448637094,3.8520371556872264,0.5646389006836805,3.1093432588488037,0.9733415184995973,0.5223730615720535,2.414518252119156,0.39168144268614885,1.2797111548412214,0.036868377335003144,0.6268724257185203,-0.3934145562501481,-0.9234673291200788,3.1093432588488037,0.8056207329272186
2,702
Alpha/Beta hydrolase fold [IPR029058]
7
21
2.936639
0.003318
Q9HB40,Q9H3G5,P42785,Q9H6V9,P07099,P50897,P10619
Sequence
InterPro Superfamily
interpro_homologous_superfamily
96,38,8,81,18,82,63
1806,2397,18,63,2095,1591,449,8,2469,706,82,2110,1519,188,1018,38,81,96,881,2121,1279
-0.33631253477906203,-0.8566010715319217,3.387793650350235,2.4530486238043636,-0.540732380985242,-0.19787205833249796,0.6473133664185765,3.5552821414043194,-0.9916536280362304,0.3467667149096307,2.2632150164335987,-0.540732380985242,-0.14415202790824028,1.3895536705247618,0.13569066148578596,2.9694470635904917,2.2840378914077024,2.1337776504182426,0.2313650943574053,-0.540732380985242,-0.01377469592003253
2,702
Glycosaminoglycan metabolism
7
12
2.922574
0.003472
P15586,P54802,O43505,P06865,P16278,Q8TB61,O43252
Processes and pathways
Reactome Pathways
msigdb_reactome
164,141,78,177,19,181,91
91,78,1110,177,919,261,164,19,141,1518,181,2431
2.1559035701841203,2.3250705886421623,0.06187795047934465,1.435179083173316,0.18391141717841533,1.0621410964140288,1.5528345987170111,3.3763606176597847,1.678647365092368,-0.14415202790824028,1.4200644560622815,-0.8898717216903321
2,702
Alcohol binding
8
14
2.917705
0.003526
O15118,Q9H4L5,P61916,P30536,P21796,O75477,P45880,Q14108
Functions
GO Molecular function
msigdb_gomf
74,381,240,114,23,313,26,30
1034,74,313,2094,1920,23,1772,1849,114,26,240,30,428,381
0.1112864967658255,2.3553210205573603,0.9000909263071639,-0.540732380985242,-0.4223492971351874,3.300030759770216,-0.308138168176809,-0.36473682773465654,1.9115709631930478,3.2819030749164693,1.1310694730368478,3.1093432588488037,0.687750303214672,0.7668911001385372
2,702
Endoplasmic reticulum golgi intermediate compartment membrane
10
19
2.916242
0.003543
Q12907,Q13190,Q9Y3B3,Q15363,Q9Y282,P24390,O15260,Q9BVK6,Q15904,P49755
Localization
GO Cellular component
msigdb_gocc
221,452,68,37,6,7,140,205,505,378
140,1335,1340,500,7,1848,1648,378,622,686,1084,221,452,37,505,205,6,1331,68
1.692221906453172,-0.06526800225829026,-0.06526800225829026,0.5855369618145146,3.630300382746048,-0.36473682773465654,-0.22508051495738804,0.7668911001385372,0.4359099189969065,0.36931090448637094,0.08668311743058034,1.1982044600111101,0.6473133664185765,2.9694470635904917,0.5855369618145146,1.2957016226393265,3.8351492091685384,-0.03941367046144973,2.424219700870432
2,702
Mitochondrial protein import
13
34
2.914092
0.003567
Q9NS69,Q99595,O95169,P12236,Q13505,O14925,Q9Y512,Q9NX63,Q8N4H5,Q5JRX3,P21796,Q15388,Q9Y5J7
Processes and pathways
Reactome Pathways
msigdb_reactome
0,1,259,267,46,206,343,311,52,182,23,413,254
206,674,2509,700,2600,594,758,259,891,1115,893,2450,794,267,23,1717,2211,1129,46,413,1013,182,52,1,2309,1058,1144,0,311,429,1065,343,254,650
1.2797111548412214,0.36931090448637094,-1.0964994453628252,0.3467667149096307,-1.4309487853394973,0.45777194879673416,0.3011488166696212,1.0621410964140288,0.20773293514525631,0.06187795047934465,0.20773293514525631,-0.957392920200188,0.27807073501123514,1.044619903415622,3.300030759770216,-0.2802102847132027,-0.6324042683431318,0.06187795047934465,2.753410498029949,0.7077496739843829,0.13569066148578596,1.404856290131458,2.617799486981324,4.159262994962356,-0.7266710972825526,0.1112864967658255,0.06187795047934465,4.4345567444728164,0.9185931557162074,0.687750303214672,0.1112864967658255,0.8438063884694104,1.0795454359625347,0.4138804266239855
2,702
er
34
77
2.899015
0.003743
P48449,O95470,Q9NTJ5,O00264,P48651,P46977,O00400,O00767,Q9P0I2,Q15363,Q969Q5,Q14739,Q5J8M3,Q9BZF1,Q15392,Q16850,Q00765,Q13190,Q9NR31,P84095,O15173,Q9Y487,Q07065,Q96A33,Q8N4V1,Q8NF37,Q9NQC3,Q06136,O96005,O95674,Q9P2W9,Q8WUX9,P49755,Q9Y5M8
Localization
OpenCell Localization
opencell_localization
130,133,543,394,410,285,155,405,558,37,427,298,426,428,49,50,566,452,589,450,70,204,328,330,79,471,88,106,110,368,116,507,378,124
394,155,405,1034,70,1541,2687,1035,1392,1340,1238,1712,133,368,110,2435,1343,995,2465,920,1718,703,1298,285,130,410,378,1405,2104,622,2380,2559,1855,686,2470,450,566,106,328,1933,452,298,2651,37,49,799,2285,50,426,2025,2455,1173,79,1138,471,663,1020,507,1825,805,427,806,330,1270,428,607,1272,88,589,543,558,1472,116,1187,1537,204,124
0.7276051859633127,1.5955163931080725,0.7077496739843829,0.1112864967658255,2.404770322309479,-0.17089694126863775,-4.022459552775041,0.1112864967658255,-0.09134055376869563,-0.06526800225829026,-0.01377469592003253,-0.2802102847132027,1.7191369886638892,0.7863246738934979,1.948174938611977,-0.9234673291200788,-0.06526800225829026,0.13569066148578596,-0.9916536280362304,0.18391141717841533,-0.2802102847132027,0.3467667149096307,-0.03941367046144973,0.9913427102790784,1.7850921167036022,0.7077496739843829,0.7668911001385372,-0.09134055376869563,-0.540732380985242,0.4359099189969065,-0.8236504561955251,-1.241316825230039,-0.36473682773465654,0.36931090448637094,-0.9916536280362304,0.6473133664185765,0.5010015722710037,2.042939361579597,0.8626989686693847,-0.4223492971351874,0.6473133664185765,0.9552170880450557,-2.0198857548091578,2.9694470635904917,2.71205420662372,0.27807073501123514,-0.6949533822984102,2.71205420662372,0.687750303214672,-0.4810044712723359,-0.957392920200188,0.036868377335003144,2.3250705886421623,0.06187795047934465,0.6268724257185203,0.39168144268614885,0.13569066148578596,0.5855369618145146,-0.33631253477906203,0.27807073501123514,0.687750303214672,0.27807073501123514,0.8626989686693847,-0.01377469592003253,0.687750303214672,0.45777194879673416,-0.01377469592003253,2.188669927046933,0.47946851200506696,0.5435848808587928,0.5223730615720535,-0.1176342396375531,1.8992357988485726,0.036868377335003144,-0.14415202790824028,1.3115908775571128,1.849210343127848
2,702
Glycosidase
9
18
2.89559
0.003784
P08236,P54802,P06865,Q16706,P16278,Q9BTY2,P06280,O60502,P04062
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
261,141,177,278,19,281,215,54,125
2448,1587,54,125,1114,215,177,919,261,317,19,831,141,932,2138,1860,278,281
-0.957392920200188,-0.19787205833249796,2.582356770154656,1.8365297753474792,0.06187795047934465,1.247422490494699,1.435179083173316,0.18391141717841533,1.0621410964140288,0.881460002398148,3.3763606176597847,0.254810254426627,1.678647365092368,0.18391141717841533,-0.5710083209352036,-0.36473682773465654,1.0092219778652174,1.0092219778652174
2,702
Phospholipid binding
27
76
2.895065
0.003791
P30086,P07602,P50995,Q9H0H5,P04083,P21796,P45880,P31749,Q14108,Q13045,Q641Q2,Q9BZF1,Q9UJZ1,O60443,P48739,Q8WTV0,Q8IYI6,O14773,P50897,O14964,Q92643,Q9Y5X3,Q9NZJ7,O60313,P53367,P21359,O15020
Functions
GO Molecular function
msigdb_gomf
385,11,516,145,395,23,26,409,30,425,554,428,446,55,314,69,586,199,82,331,220,498,365,239,247,502,376
576,2584,2463,911,199,331,376,1838,1336,1070,239,55,1284,653,1237,395,1434,11,1549,1920,1242,2586,1244,1844,702,502,23,853,385,409,1198,1925,26,2637,925,314,82,516,247,710,1044,425,974,740,1131,30,643,1510,554,2552,586,1018,1176,69,905,220,647,2504,1267,1374,1662,1270,428,145,1579,365,1835,446,1704,910,1232,1385,1801,2122,2447,498
0.47946851200506696,-1.353903802647287,-0.9916536280362304,0.18391141717841533,1.3115908775571128,0.8438063884694104,0.7668911001385372,-0.36473682773465654,-0.06526800225829026,0.08668311743058034,1.1310694730368478,2.5279649567157563,-0.03941367046144973,0.39168144268614885,-0.01377469592003253,0.7276051859633127,-0.1176342396375531,3.503168251453378,-0.17089694126863775,-0.4223492971351874,-0.01377469592003253,-1.353903802647287,-0.01377469592003253,-0.36473682773465654,0.3467667149096307,0.5855369618145146,3.300030759770216,0.2313650943574053,0.74731846202068,0.7077496739843829,0.011651732815977752,-0.4223492971351874,3.2819030749164693,-1.7139948007237693,0.18391141717841533,0.9000909263071639,2.2632150164335987,0.5646389006836805,1.0968341446394454,0.3467667149096307,0.1112864967658255,0.687750303214672,0.15989814001547026,0.3240467416918007,0.06187795047934465,3.1093432588488037,0.4138804266239855,-0.14415202790824028,0.5223730615720535,-1.2045569767363151,0.47946851200506696,0.13569066148578596,0.036868377335003144,2.414518252119156,0.20773293514525631,1.2147165622569294,0.4138804266239855,-1.0612014774574168,-0.01377469592003253,-0.06526800225829026,-0.22508051495738804,-0.01377469592003253,0.687750303214672,1.6649938710643004,-0.17089694126863775,0.8056207329272186,-0.33631253477906203,0.6676054254045067,-0.25252550560044684,0.20773293514525631,0.011651732815977752,-0.06526800225829026,-0.308138168176809,-0.540732380985242,-0.9234673291200788,0.6062808758329494
2,702
Nervous system process
32
87
2.882818
0.003941
Q13432,Q13641,O00264,P49768,P42858,Q9UQB8,Q14108,P31749,O43924,Q9Y6M9,Q9H0U3,Q6Y7W6,O60443,O75844,Q15555,P10253,O14773,Q9BPZ3,Q7Z406,P50897,Q9Y5J7,Q92542,Q8N0X7,Q9Y639,Q14203,Q99797,P07196,O60313,P17900,P78417,P21359,P04062
Processes and pathways
GO Biological process
msigdb_gobp
5,521,394,397,532,31,30,409,36,178,443,180,55,57,186,317,199,208,468,82,254,222,350,367,486,108,360,239,113,249,502,125
1706,394,199,36,239,55,1286,1765,2547,1840,1482,594,57,1238,1964,125,1841,2346,2201,1637,360,919,317,1345,113,920,502,680,2172,1720,2498,409,1038,2323,1400,619,532,2269,1725,1558,397,762,82,2242,2273,1563,249,2453,2539,1567,5,974,521,30,1132,486,1362,601,186,1863,2024,180,604,468,1787,350,2150,2230,222,2615,877,1830,1320,108,557,208,443,2565,1756,2441,2194,1278,31,254,650,367,178
-0.2802102847132027,0.7276051859633127,1.3115908775571128,2.9767096391211663,1.1310694730368478,2.5279649567157563,-0.03941367046144973,-0.308138168176809,-1.2045569767363151,-0.36473682773465654,-0.14415202790824028,0.45777194879673416,2.5094973738711897,-0.01377469592003253,-0.4515446964616516,1.8365297753474792,-0.36473682773465654,-0.7910150544529415,-0.6324042683431318,-0.22508051495738804,0.8056207329272186,0.18391141717841533,0.881460002398148,-0.06526800225829026,1.9115709631930478,0.18391141717841533,0.5855369618145146,0.36931090448637094,-0.6015642502581877,-0.2802102847132027,-1.0612014774574168,0.7077496739843829,0.1112864967658255,-0.7586901436735312,-0.09134055376869563,0.4359099189969065,0.5435848808587928,-0.6949533822984102,-0.2802102847132027,-0.17089694126863775,0.7276051859633127,0.3011488166696212,2.2632150164335987,-0.6635325569459647,-0.6949533822984102,-0.17089694126863775,1.0968341446394454,-0.957392920200188,-1.1681714201941449,-0.17089694126863775,3.8520371556872264,0.15989814001547026,0.5646389006836805,3.1093432588488037,0.06187795047934465,0.6062808758329494,-0.06526800225829026,0.45777194879673416,1.3895536705247618,-0.36473682773465654,-0.4810044712723359,1.4200644560622815,0.45777194879673416,0.6268724257185203,-0.308138168176809,0.8247808034059452,-0.5710083209352036,-0.6324042683431318,1.1982044600111101,-1.5096459874254489,0.2313650943574053,-0.33631253477906203,-0.03941367046144973,1.9960644529824567,0.5223730615720535,1.2797111548412214,0.6676054254045067,-1.241316825230039,-0.2802102847132027,-0.9234673291200788,-0.6015642502581877,-0.01377469592003253,3.1093432588488037,1.0795454359625347,0.4138804266239855,0.8056207329272186,1.435179083173316
2,702
Transport vesicle
30
80
2.880133
0.003975
P24390,O15260,P49768,Q12846,P20020,Q15363,P10321,P20645,Q86Y82,O43760,Q13190,Q9NR31,Q9Y3B3,P11279,P51790,O00429,O95249,Q9BVK6,P50897,P11717,O00461,Q15334,P61421,Q92542,Q15907,Q9BT78,Q14141,O95487,P49755,Q9Y678
Localization
GO Cellular component
msigdb_gocc
7,140,397,536,531,37,419,175,438,65,452,589,68,318,198,447,200,205,82,457,90,601,463,222,349,493,233,359,378,393
447,90,1916,1632,913,140,728,1335,1236,65,730,1338,1392,1340,1840,1073,200,1589,359,791,1548,1243,759,419,318,457,531,1809,175,7,1680,895,1442,1721,1445,1648,378,397,82,1078,1405,2104,198,1602,1727,1854,763,928,2595,1125,463,623,739,1127,536,452,974,233,1047,2421,601,37,1571,2142,349,438,222,2255,1139,493,205,2116,1026,589,1426,2682,2431,68,393,958
0.6473133664185765,2.1559035701841203,-0.4223492971351874,-0.22508051495738804,0.18391141717841533,1.692221906453172,0.3240467416918007,-0.06526800225829026,-0.01377469592003253,2.4434845439398956,0.3240467416918007,-0.06526800225829026,-0.09134055376869563,-0.06526800225829026,-0.36473682773465654,0.08668311743058034,1.3115908775571128,-0.19787205833249796,0.8056207329272186,0.27807073501123514,-0.17089694126863775,-0.01377469592003253,0.3011488166696212,0.687750303214672,0.881460002398148,0.6268724257185203,0.5435848808587928,-0.33631253477906203,1.4651313202975424,3.630300382746048,-0.25252550560044684,0.20773293514525631,-0.1176342396375531,-0.2802102847132027,-0.1176342396375531,-0.22508051495738804,0.7668911001385372,0.7276051859633127,2.2632150164335987,0.08668311743058034,-0.09134055376869563,-0.540732380985242,1.3273799247937976,-0.19787205833249796,-0.2802102847132027,-0.36473682773465654,0.3011488166696212,0.18391141717841533,-1.392223197306997,0.06187795047934465,0.6268724257185203,0.4359099189969065,0.3240467416918007,0.06187795047934465,0.5435848808587928,0.6473133664185765,0.15989814001547026,1.148018452189637,0.1112864967658255,-0.8898717216903321,0.45777194879673416,2.9694470635904917,-0.17089694126863775,-0.5710083209352036,0.8247808034059452,0.6676054254045067,1.1982044600111101,-0.6635325569459647,0.06187795047934465,0.6062808758329494,1.2957016226393265,-0.540732380985242,0.13569066148578596,0.47946851200506696,-0.09134055376869563,-3.0494230058693037,-0.8898717216903321,2.424219700870432,0.74731846202068,0.18391141717841533
2,702
Outer membrane
30
78
2.876366
0.004023
Q9NS69,Q5VT66,O43169,Q9Y6C9,O00264,P49768,Q99720,P21796,P45880,Q15388,Q9NQZ5,Q13505,Q9UBM7,Q9NX63,Q8N4H5,Q6NUM9,Q9BUR5,Q99536,Q9Y512,P09601,Q9NVH1,Q8TB36,Q8N0X7,Q709C8,Q9Y277,Q9NZJ7,O60313,P30536,P50402,Q8IWA4
Localization
GO Cellular component
msigdb_gocc
0,131,15,273,394,397,22,23,26,413,40,46,445,311,52,315,340,339,343,211,355,352,350,363,237,365,239,114,243,373
394,447,2696,15,239,1479,700,758,962,891,2435,2534,1118,211,2322,23,114,2208,2661,2211,619,1494,26,397,243,1202,1650,517,1408,2419,2670,46,1414,1362,413,2526,568,869,131,718,315,944,363,1689,373,1017,2149,350,52,1986,2150,352,1092,1177,648,1792,339,525,22,508,340,2116,723,2192,40,1906,0,1322,355,311,1186,365,445,817,237,1032,343,273
0.7276051859633127,0.6473133664185765,-6.033615657446484,3.3991465956104387,1.1310694730368478,-0.14415202790824028,0.3467667149096307,0.3011488166696212,0.15989814001547026,0.20773293514525631,-0.9234673291200788,-1.1681714201941449,0.06187795047934465,1.2636184551493796,-0.7586901436735312,3.300030759770216,1.9115709631930478,-0.6324042683431318,-2.2060868946246557,-0.6324042683431318,0.4359099189969065,-0.14415202790824028,3.2819030749164693,0.7276051859633127,1.1140084276296076,0.011651732815977752,-0.22508051495738804,0.5646389006836805,-0.09134055376869563,-0.8898717216903321,-2.401380604447,2.753410498029949,-0.09134055376869563,-0.06526800225829026,0.7077496739843829,-1.1321541889327764,0.5010015722710037,0.2313650943574053,1.7850921167036022,0.3467667149096307,0.9000909263071639,0.18391141717841533,0.8056207329272186,-0.25252550560044684,0.7863246738934979,0.13569066148578596,-0.5710083209352036,0.8247808034059452,2.617799486981324,-0.4515446964616516,-0.5710083209352036,0.8247808034059452,0.08668311743058034,0.036868377335003144,0.4138804266239855,-0.308138168176809,0.8438063884694104,0.5646389006836805,3.3179623931981417,0.5855369618145146,0.8438063884694104,-0.540732380985242,0.3467667149096307,-0.6015642502581877,2.9401004245140965,-0.3934145562501481,4.4345567444728164,-0.03941367046144973,0.8247808034059452,0.9185931557162074,0.036868377335003144,0.8056207329272186,0.6676054254045067,0.27807073501123514,1.148018452189637,0.13569066148578596,0.8438063884694104,1.026980616676179
2,702
Sterol metabolic process
15
32
2.855601
0.004296
Q9BQE5,P48449,Q15800,Q8WTV0,Q6P1A2,Q14739,O15118,P16435,P61916,Q15392,Q16850,Q9UBM7,O75477,Q14534,P04062
Processes and pathways
GO Biological process
msigdb_gobp
34,130,67,69,227,298,74,361,240,49,50,445,313,412,125
74,313,595,2094,2435,125,1677,963,361,2587,579,449,2102,130,564,1928,240,1730,1819,2139,412,298,1982,49,799,67,50,227,69,34,445,1276
2.3553210205573603,0.9000909263071639,0.45777194879673416,-0.540732380985242,-0.9234673291200788,1.8365297753474792,-0.25252550560044684,0.15989814001547026,0.8056207329272186,-1.353903802647287,0.47946851200506696,0.6473133664185765,-0.540732380985242,1.7850921167036022,0.5010015722710037,-0.4223492971351874,1.1310694730368478,-0.2802102847132027,-0.33631253477906203,-0.5710083209352036,0.7077496739843829,0.9552170880450557,-0.4515446964616516,2.71205420662372,0.27807073501123514,2.433875016635886,2.71205420662372,1.1815848149569044,2.414518252119156,3.0547069293922724,0.6676054254045067,-0.01377469592003253
2,702
Sphingolipid metabolic process
13
25
2.855245
0.0043
Q96G23,O95470,Q13510,Q9NZJ7,Q06136,P07602,P06865,P17900,P16278,P50897,P06280,Q9P035,P04062
Processes and pathways
GO Biological process
msigdb_gobp
99,133,134,365,106,11,177,113,19,82,215,357,125
1541,2687,133,125,215,177,11,919,19,113,853,1157,82,106,134,2145,869,1018,99,390,1186,2193,365,357,1472
-0.17089694126863775,-4.022459552775041,1.7191369886638892,1.8365297753474792,1.247422490494699,1.435179083173316,3.503168251453378,0.18391141717841533,3.3763606176597847,1.9115709631930478,0.2313650943574053,0.036868377335003144,2.2632150164335987,2.042939361579597,1.7191369886638892,-0.5710083209352036,0.2313650943574053,0.13569066148578596,2.122628808729958,0.74731846202068,0.036868377335003144,-0.6015642502581877,0.8056207329272186,0.8247808034059452,-0.1176342396375531
2,702
primary active transporter
12
24
2.850951
0.004359
Q9NS69,O75381,Q6P4A7,O60888,Q96NB2,Q9BUN8,P16615,Q8N4H5,Q15388,P12270,Q9Y5J7,P20020
Functions
Panther Protein class
panther_protein_class
0,345,41,10,473,209,369,52,413,501,254,531
10,345,758,891,615,1674,501,369,531,680,1816,1932,413,940,555,41,52,744,473,209,1181,1144,0,254
3.5189857909692703,0.8247808034059452,0.3011488166696212,0.20773293514525631,0.4359099189969065,-0.25252550560044684,0.5855369618145146,0.7863246738934979,0.5435848808587928,0.36931090448637094,-0.33631253477906203,-0.4223492971351874,0.7077496739843829,0.18391141717841533,0.5223730615720535,2.8568664927325975,2.617799486981324,0.3240467416918007,0.6268724257185203,1.2797111548412214,0.036868377335003144,0.06187795047934465,4.4345567444728164,1.0795454359625347
2,702
Hydrolase activity acting on glycosyl bonds
13
25
2.826296
0.004709
P08236,O75503,P10253,P29372,P54802,P06865,P17900,Q16706,P16278,Q9BTY2,O60502,P06280,P04062
Functions
GO Molecular function
msigdb_gomf
261,406,317,448,141,177,113,278,19,281,54,215,125
2448,1587,54,406,125,1114,215,177,919,261,317,2399,19,113,459,1680,448,831,141,932,2138,1860,278,281,881
-0.957392920200188,-0.19787205833249796,2.582356770154656,0.7077496739843829,1.8365297753474792,0.06187795047934465,1.247422490494699,1.435179083173316,0.18391141717841533,1.0621410964140288,0.881460002398148,-0.8566010715319217,3.3763606176597847,1.9115709631930478,0.6268724257185203,-0.25252550560044684,0.6473133664185765,0.254810254426627,1.678647365092368,0.18391141717841533,-0.5710083209352036,-0.36473682773465654,1.0092219778652174,1.0092219778652174,0.2313650943574053
2,702
Cation transport
50
134
2.813322
0.004903
Q02790,Q9Y376,Q99623,Q9HD20,Q70HW3,P62258,P13073,P49768,P21796,P05141,O43808,P42858,O00400,P20020,P31749,P00403,P21281,P24539,P07384,P61201,Q9Y6M7,Q9H0U3,Q9UJZ1,O43772,O75844,Q9Y289,Q8IWX8,Q9HC21,Q7KZN9,O15173,P51790,O00429,Q96ES6,Q9BPX6,Q96NB2,Q8N4V1,P62942,Q9H2H9,P02786,O95202,P61421,Q9UDW1,Q15907,O75964,Q96QD8,Q16795,Q8NEW0,P16615,P30536,P78417
Processes and pathways
GO Biological process
msigdb_gobp
520,392,525,136,14,400,269,397,23,274,283,532,155,531,409,407,291,296,42,423,305,443,446,56,57,184,187,323,195,70,198,447,76,474,473,79,83,210,333,332,463,98,349,94,492,488,109,369,114,249
1708,155,447,1067,1762,70,848,56,283,2449,1286,757,2667,2600,57,1673,94,332,407,333,2511,615,1674,274,2201,1115,1434,42,1920,1435,893,1639,1844,1677,794,269,2003,369,1245,2557,531,1249,291,2127,2051,23,680,296,1717,1680,1720,2524,114,1294,409,2468,1348,2054,968,922,1721,532,1852,1444,2378,397,1163,198,1164,1816,2688,657,423,463,580,400,83,249,1932,933,1127,520,712,863,1567,936,1782,1654,2581,601,940,349,2526,488,1364,14,195,187,2571,79,691,109,665,804,2544,76,1371,473,1221,492,2593,525,557,474,779,443,210,1181,323,136,2441,98,2431,1799,446,1704,1187,1879,1232,184,392,820,885,305
-0.2802102847132027,1.5955163931080725,0.6473133664185765,0.08668311743058034,-0.308138168176809,2.404770322309479,0.2313650943574053,2.5187525853416863,0.9913427102790784,-0.957392920200188,-0.03941367046144973,0.3011488166696212,-2.302553966333245,-1.4309487853394973,2.5094973738711897,-0.25252550560044684,2.1337776504182426,0.8438063884694104,0.7077496739843829,0.8438063884694104,-1.0964994453628252,0.4359099189969065,-0.25252550560044684,1.0092219778652174,-0.6324042683431318,0.06187795047934465,-0.1176342396375531,2.849109236264797,-0.4223492971351874,-0.1176342396375531,0.20773293514525631,-0.22508051495738804,-0.36473682773465654,-0.25252550560044684,0.27807073501123514,1.026980616676179,-0.4810044712723359,0.7863246738934979,-0.01377469592003253,-1.241316825230039,0.5435848808587928,-0.01377469592003253,0.9733415184995973,-0.5710083209352036,-0.5107324113409443,3.300030759770216,0.36931090448637094,0.9552170880450557,-0.2802102847132027,-0.25252550560044684,-0.2802102847132027,-1.1321541889327764,1.9115709631930478,-0.03941367046144973,0.7077496739843829,-0.9916536280362304,-0.06526800225829026,-0.5107324113409443,0.15989814001547026,0.18391141717841533,-0.2802102847132027,0.5435848808587928,-0.36473682773465654,-0.1176342396375531,-0.8236504561955251,0.7276051859633127,0.036868377335003144,1.3273799247937976,0.036868377335003144,-0.33631253477906203,-4.476245528731529,0.39168144268614885,0.687750303214672,0.6268724257185203,0.47946851200506696,0.7276051859633127,2.2632150164335987,1.0968341446394454,-0.4223492971351874,0.18391141717841533,0.06187795047934465,0.5646389006836805,0.3467667149096307,0.2313650943574053,-0.17089694126863775,0.18391141717841533,-0.308138168176809,-0.22508051495738804,-1.315983932120922,0.45777194879673416,0.18391141717841533,0.8247808034059452,-1.1321541889327764,0.6062808758329494,-0.06526800225829026,3.4216157303597954,1.3430697559709033,1.3895536705247618,-1.2784570650664284,2.3250705886421623,0.36931090448637094,1.9602443238318379,0.39168144268614885,0.27807073501123514,-1.1681714201941449,2.3452866902285905,-0.06526800225829026,0.6268724257185203,0.011651732815977752,0.6062808758329494,-1.353903802647287,0.5646389006836805,0.5223730615720535,0.6268724257185203,0.3011488166696212,0.6676054254045067,1.2797111548412214,0.036868377335003144,0.881460002398148,1.7191369886638892,-0.9234673291200788,2.1337776504182426,-0.8898717216903321,-0.308138168176809,0.6676054254045067,-0.25252550560044684,0.036868377335003144,-0.36473682773465654,0.011651732815977752,1.404856290131458,0.74731846202068,0.27807073501123514,0.2313650943574053,0.9369680850132093
2,702
Dementia
22
49
2.803496
0.005055
Q13510,P07602,P35637,P49768,P42858,Q14108,P00403,Q9NQZ5,P04350,P06865,Q6Y7W6,O00429,Q9Y487,O15118,Q709C8,Q9UBB4,Q9NZJ7,Q14203,O60313,P61916,P17900,P04062
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
134,11,270,397,532,30,407,40,300,177,180,447,204,74,363,366,365,486,239,240,113,125
447,74,1337,239,1287,891,407,125,1714,300,177,11,1484,2372,113,998,828,551,1488,2535,2650,270,922,1721,532,1495,397,2242,1929,2380,240,1007,1507,134,30,486,1822,180,363,1986,1870,2232,877,2593,1946,40,365,366,204
0.6473133664185765,2.3553210205573603,-0.06526800225829026,1.1310694730368478,-0.03941367046144973,0.20773293514525631,0.7077496739843829,1.8365297753474792,-0.2802102847132027,0.9369680850132093,1.435179083173316,3.503168251453378,-0.14415202790824028,-0.8236504561955251,1.9115709631930478,0.13569066148578596,0.254810254426627,0.5223730615720535,-0.14415202790824028,-1.1681714201941449,-2.0198857548091578,1.026980616676179,0.18391141717841533,-0.2802102847132027,0.5435848808587928,-0.14415202790824028,0.7276051859633127,-0.6635325569459647,-0.4223492971351874,-0.8236504561955251,1.1310694730368478,0.13569066148578596,-0.14415202790824028,1.7191369886638892,3.1093432588488037,0.6062808758329494,-0.33631253477906203,1.4200644560622815,0.8056207329272186,-0.4515446964616516,-0.36473682773465654,-0.6324042683431318,0.2313650943574053,-1.353903802647287,-0.4223492971351874,2.9401004245140965,0.8056207329272186,0.8056207329272186,1.3115908775571128
2,702
secondary carrier transporter
9
15
2.797298
0.005153
Q9UBX3,Q6NT16,Q96ES6,Q9Y6M7,O95202,Q8TB61,Q9Y289,Q9BQT8,O00400
Functions
Panther Protein class
panther_protein_class
103,75,76,305,332,181,184,120,155
155,594,332,514,835,75,2025,181,76,120,779,103,429,184,305
1.5955163931080725,0.45777194879673416,0.8438063884694104,0.5646389006836805,0.254810254426627,2.3553210205573603,-0.4810044712723359,1.4200644560622815,2.3452866902285905,1.8743612216621832,0.3011488166696212,2.088833108363494,0.687750303214672,1.404856290131458,0.9369680850132093
2,702
Endoplasmic reticulum organization
19
38
2.765934
0.005676
Q15629,O95197,Q9P0I2,Q15363,Q5J8M3,P46379,Q00765,O14976,O00429,Q96A33,A0FGR8,Q8N4V1,P61619,Q9NQC3,Q12907,Q6P1A2,Q9P2W9,P57088,O43765
Processes and pathways
GO Biological process
msigdb_gobp
29,33,558,37,426,168,566,560,447,330,576,79,580,88,221,227,116,248,499
576,447,560,1632,1035,1337,499,1073,33,1712,168,1648,762,248,580,566,221,1933,2651,37,29,426,1260,227,2680,79,1138,1264,663,330,1270,607,1272,88,1186,558,1472,116
0.47946851200506696,0.6473133664185765,0.5010015722710037,-0.22508051495738804,0.1112864967658255,-0.06526800225829026,0.5855369618145146,0.08668311743058034,3.082238226873909,-0.2802102847132027,1.5239522688610696,-0.22508051495738804,0.3011488166696212,1.0968341446394454,0.47946851200506696,0.5010015722710037,1.1982044600111101,-0.4223492971351874,-2.0198857548091578,2.9694470635904917,3.1293985059553213,0.687750303214672,-0.01377469592003253,1.1815848149569044,-3.0494230058693037,2.3250705886421623,0.06187795047934465,-0.01377469592003253,0.39168144268614885,0.8626989686693847,-0.01377469592003253,0.45777194879673416,-0.01377469592003253,2.188669927046933,0.036868377335003144,0.5223730615720535,-0.1176342396375531,1.8992357988485726
2,702
Peptidase activity
29
103
2.765617
0.005682
Q16740,Q92820,P28072,P42785,Q9NZ08,P49721,P55786,Q9H3G5,P07384,P20618,Q5JRX3,O75844,Q9UIQ6,Q96FW1,P10619,P67812,P52888,Q86UV5,O14773,P28070,Q9BYT8,Q92643,Q92542,P42892,Q9HB40,Q99797,Q8TCT9,Q8TCT8,Q9UPU5
Functions
GO Molecular function
msigdb_gomf
128,264,129,8,137,20,157,38,42,295,182,57,58,316,63,72,73,337,199,207,92,220,222,95,96,108,244,115,121
1280,2262,199,1235,561,2600,57,562,2001,1153,333,42,2411,63,2644,1591,2413,295,1487,1847,207,129,433,2467,2010,1850,2701,1350,2012,1401,8,95,1723,2469,1814,20,397,1448,73,1891,2136,2300,157,436,1203,72,2697,1129,2246,1085,453,2141,1414,1511,128,2110,1937,182,1895,555,1212,2551,2527,1089,1519,337,115,244,222,220,264,1420,1139,1791,1660,806,316,746,2475,1945,1268,442,1024,2593,1830,108,1374,493,92,38,1949,781,96,1530,1992,2118,909,137,509,58,121,820,2123
-0.03941367046144973,-0.6949533822984102,1.3115908775571128,-0.01377469592003253,0.5010015722710037,-1.4309487853394973,2.5094973738711897,0.5010015722710037,-0.4810044712723359,0.036868377335003144,0.8438063884694104,2.849109236264797,-0.8898717216903321,2.4530486238043636,-1.9299894948150549,-0.19787205833249796,-0.8898717216903321,0.9552170880450557,-0.14415202790824028,-0.36473682773465654,1.2797111548412214,1.7850921167036022,0.6676054254045067,-0.9916536280362304,-0.4810044712723359,-0.36473682773465654,-7.296535538848486,-0.06526800225829026,-0.4810044712723359,-0.09134055376869563,3.5552821414043194,2.1337776504182426,-0.2802102847132027,-0.9916536280362304,-0.33631253477906203,3.3590589468435246,0.7276051859633127,-0.1176342396375531,2.3949755597742,-0.3934145562501481,-0.5710083209352036,-0.7266710972825526,1.5955163931080725,0.6676054254045067,0.011651732815977752,2.404770322309479,-6.468314273842489,0.06187795047934465,-0.6635325569459647,0.08668311743058034,0.6473133664185765,-0.5710083209352036,-0.09134055376869563,-0.14415202790824028,1.7980601075871823,-0.540732380985242,-0.4223492971351874,1.404856290131458,-0.3934145562501481,0.5223730615720535,0.011651732815977752,-1.2045569767363151,-1.1321541889327764,0.08668311743058034,-0.14415202790824028,0.8438063884694104,1.9115709631930478,1.1140084276296076,1.1982044600111101,1.2147165622569294,1.0621410964140288,-0.09134055376869563,0.06187795047934465,-0.308138168176809,-0.22508051495738804,0.27807073501123514,0.9000909263071639,0.3240467416918007,-0.9916536280362304,-0.4223492971351874,-0.01377469592003253,0.6676054254045067,0.13569066148578596,-1.353903802647287,-0.33631253477906203,1.9960644529824567,-0.06526800225829026,0.6062808758329494,2.1559035701841203,2.9694470635904917,-0.4223492971351874,0.3011488166696212,2.1337776504182426,-0.14415202790824028,-0.4515446964616516,-0.540732380985242,0.20773293514525631,1.7191369886638892,0.5855369618145146,2.500199007739095,1.8743612216621832,0.27807073501123514,-0.540732380985242
2,702
Organophosphate ester transport
14
26
2.763902
0.005711
Q9HC21,P08183,Q8WTV0,P12236,P61916,Q08722,Q8TB61,P05141,Q6NUK1,P48739,O43808,Q9H2D1,O00400,Q14108
Processes and pathways
GO Biological process
msigdb_gobp
323,197,69,267,240,411,181,274,414,314,283,60,155,30
155,479,283,274,197,794,267,853,1772,2558,856,314,240,411,30,1364,414,744,181,2614,69,557,428,60,323,1472
1.5955163931080725,0.6062808758329494,0.9913427102790784,1.0092219778652174,1.3273799247937976,0.27807073501123514,1.044619903415622,0.2313650943574053,-0.308138168176809,-1.241316825230039,0.2313650943574053,0.9000909263071639,1.1310694730368478,0.7077496739843829,3.1093432588488037,-0.06526800225829026,0.7077496739843829,0.3240467416918007,1.4200644560622815,-1.5096459874254489,2.414518252119156,0.5223730615720535,0.687750303214672,2.4814715373825837,0.881460002398148,-0.1176342396375531
2,702
Liposaccharide metabolic process
6
12
2.758238
0.005811
Q8NBX0,P06865,P17900,P16278,P06280,P04062
Processes and pathways
GO Biological process
msigdb_gobp
102,177,113,19,215,125
125,1114,215,177,919,19,113,2145,102,220,778,390
1.8365297753474792,0.06187795047934465,1.247422490494699,1.435179083173316,0.18391141717841533,3.3763606176597847,1.9115709631930478,-0.5710083209352036,2.1114220884425734,1.2147165622569294,0.3011488166696212,0.74731846202068
2,702
Steroid metabolic process
21
58
2.754753
0.005874
P48449,O95470,Q13510,Q14534,P38435,Q9BQE5,Q53GQ0,Q14739,Q15392,Q16850,Q9UBM7,O75477,Q15800,Q8WTV0,O15118,Q6P1A2,P16435,P61916,P30536,Q9H4L5,P04062
Processes and pathways
GO Biological process
msigdb_gobp
130,133,134,412,156,34,292,298,49,50,445,313,67,69,74,227,361,240,114,381,125
74,313,595,2094,133,2435,125,615,2575,1677,963,2373,361,853,1772,2587,2239,617,114,579,156,449,2102,130,564,2242,1853,1928,240,1730,1819,712,134,2139,412,298,1982,49,487,1686,799,67,50,292,773,227,69,2664,2362,1830,2308,34,879,381,445,1276,2082,1667
2.3553210205573603,0.9000909263071639,0.45777194879673416,-0.540732380985242,1.7191369886638892,-0.9234673291200788,1.8365297753474792,0.4359099189969065,-1.315983932120922,-0.25252550560044684,0.15989814001547026,-0.8236504561955251,0.8056207329272186,0.2313650943574053,-0.308138168176809,-1.353903802647287,-0.6635325569459647,0.4359099189969065,1.9115709631930478,0.47946851200506696,1.5955163931080725,0.6473133664185765,-0.540732380985242,1.7850921167036022,0.5010015722710037,-0.6635325569459647,-0.36473682773465654,-0.4223492971351874,1.1310694730368478,-0.2802102847132027,-0.33631253477906203,0.3467667149096307,1.7191369886638892,-0.5710083209352036,0.7077496739843829,0.9552170880450557,-0.4515446964616516,2.71205420662372,0.6062808758329494,-0.25252550560044684,0.27807073501123514,2.433875016635886,2.71205420662372,0.9733415184995973,0.3011488166696212,1.1815848149569044,2.414518252119156,-2.2060868946246557,-0.7910150544529415,-0.33631253477906203,-0.7266710972825526,3.0547069293922724,0.2313650943574053,0.7668911001385372,0.6676054254045067,-0.01377469592003253,-0.5107324113409443,-0.22508051495738804
2,702
Endoplasmic reticulum
51
177
2.748051
0.005995
Q15293,Q8N0U8,O95470,O15460,O43852,P35790,O15260,O43169,Q8IV08,O00264,Q5BJF2,P48651,P21964,O95197,O00767,Q8WUJ1,Q9H3G5,P67809,Q9UBM7,Q16850,Q14257,Q6NUQ4,P43307,P42766,O75477,P29966,Q96KA5,P62847,Q15800,Q70UQ0,Q92791,Q96A33,Q9H3N1,Q8NF37,Q9BUN8,P83881,Q9Y680,Q9NQC3,Q9P035,P51648,Q9BV10,Q96G23,Q96CN7,Q86XL3,O96005,O95674,Q8TCT9,Q9P2W9,P50402,Q96PC5,Q86UE4
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
388,3,133,258,265,138,140,15,147,394,21,410,408,33,405,35,38,424,445,50,179,309,53,185,313,434,189,193,67,319,329,330,475,471,209,466,86,88,357,219,353,99,235,107,110,368,244,116,243,253,127
394,405,846,1146,1632,140,1541,258,15,1586,1035,265,313,1238,595,1768,2094,33,1712,133,368,110,2435,1343,995,2347,2201,892,678,825,1155,549,656,616,1439,1119,827,1716,679,2206,408,2487,459,1293,681,1848,703,434,1850,1596,1681,2701,1442,138,1297,579,1298,185,53,2131,2351,924,515,1122,1199,410,1123,1648,243,1447,2352,622,219,1004,2559,927,1406,929,580,2470,2243,1303,1930,857,1450,858,766,1081,859,739,1354,193,1502,1817,1451,2384,1126,1563,2452,424,834,466,566,713,1893,1933,659,624,2420,2138,179,1736,1860,2581,1570,388,1608,799,67,50,21,309,1517,1656,870,319,127,1054,107,1173,147,3,1986,1940,471,663,2113,1020,244,1216,35,329,805,330,667,235,1056,1023,99,876,189,747,253,1179,811,2188,1270,209,353,38,475,1064,88,589,2078,2193,357,1472,609,116,445,2313,575,2194,1187,1669,86
0.7276051859633127,0.7077496739843829,0.2313650943574053,0.036868377335003144,-0.22508051495738804,1.692221906453172,-0.17089694126863775,1.0621410964140288,3.3991465956104387,-0.19787205833249796,0.1112864967658255,1.044619903415622,0.9000909263071639,-0.01377469592003253,0.45777194879673416,-0.308138168176809,-0.540732380985242,3.082238226873909,-0.2802102847132027,1.7191369886638892,0.7863246738934979,1.948174938611977,-0.9234673291200788,-0.06526800225829026,0.13569066148578596,-0.7910150544529415,-0.6324042683431318,0.20773293514525631,0.36931090448637094,0.254810254426627,0.036868377335003144,0.5223730615720535,0.39168144268614885,0.4359099189969065,-0.1176342396375531,0.06187795047934465,0.254810254426627,-0.2802102847132027,0.36931090448637094,-0.6324042683431318,0.7077496739843829,-1.0262546953488343,0.6268724257185203,-0.03941367046144973,0.36931090448637094,-0.36473682773465654,0.3467667149096307,0.6676054254045067,-0.36473682773465654,-0.19787205833249796,-0.25252550560044684,-7.296535538848486,-0.1176342396375531,1.7057182117315222,-0.03941367046144973,0.47946851200506696,-0.03941367046144973,1.3895536705247618,2.6001584197679355,-0.5710083209352036,-0.7910150544529415,0.18391141717841533,0.5646389006836805,0.06187795047934465,0.011651732815977752,0.7077496739843829,0.06187795047934465,-0.22508051495738804,1.1140084276296076,-0.1176342396375531,-0.7910150544529415,0.4359099189969065,1.2311222135057562,0.13569066148578596,-1.241316825230039,0.18391141717841533,-0.09134055376869563,0.18391141717841533,0.47946851200506696,-0.9916536280362304,-0.6635325569459647,-0.03941367046144973,-0.4223492971351874,0.2313650943574053,-0.1176342396375531,0.2313650943574053,0.3011488166696212,0.08668311743058034,0.2313650943574053,0.3240467416918007,-0.06526800225829026,1.3586613493638433,-0.14415202790824028,-0.33631253477906203,-0.1176342396375531,-0.8236504561955251,0.06187795047934465,-0.17089694126863775,-0.957392920200188,0.687750303214672,0.254810254426627,0.6268724257185203,0.5010015722710037,0.3467667149096307,-0.3934145562501481,-0.4223492971351874,0.39168144268614885,0.4359099189969065,-0.8898717216903321,-0.5710083209352036,1.4200644560622815,-0.2802102847132027,-0.36473682773465654,-1.315983932120922,-0.17089694126863775,0.74731846202068,-0.19787205833249796,0.27807073501123514,2.433875016635886,2.71205420662372,3.3298095398885463,0.9185931557162074,-0.14415202790824028,-0.22508051495738804,0.2313650943574053,0.881460002398148,1.8237782990494262,0.1112864967658255,2.0078769667953464,0.036868377335003144,1.651260698795158,3.9764717372455145,-0.4515446964616516,-0.4223492971351874,0.6268724257185203,0.39168144268614885,-0.540732380985242,0.13569066148578596,1.1140084276296076,0.011651732815977752,3.0196771077390956,0.8626989686693847,0.27807073501123514,0.8626989686693847,0.39168144268614885,1.148018452189637,0.1112864967658255,0.13569066148578596,2.122628808729958,0.2313650943574053,1.3895536705247618,0.3240467416918007,1.0795454359625347,0.036868377335003144,0.27807073501123514,-0.6015642502581877,-0.01377469592003253,1.2797111548412214,0.8247808034059452,2.9694470635904917,0.6268724257185203,0.1112864967658255,2.188669927046933,0.47946851200506696,-0.5107324113409443,-0.6015642502581877,0.8247808034059452,-0.1176342396375531,0.45777194879673416,1.8992357988485726,0.6676054254045067,-0.7266710972825526,0.5010015722710037,-0.6015642502581877,0.036868377335003144,-0.22508051495738804,2.199481174526684
2,702
Secondary active transmembrane transporter activity
11
22
2.732202
0.006291
Q96QD8,P51790,Q9UBX3,P12236,Q96ES6,Q9Y6M7,Q9H2H9,O95202,Q9Y289,P05141,O00400
Functions
GO Molecular function
msigdb_gomf
492,198,103,267,76,305,210,332,184,274,155
155,332,514,274,1435,794,267,856,198,1683,1498,933,835,940,691,76,492,779,210,103,184,305
1.5955163931080725,0.8438063884694104,0.5646389006836805,1.0092219778652174,-0.1176342396375531,0.27807073501123514,1.044619903415622,0.2313650943574053,1.3273799247937976,-0.25252550560044684,-0.14415202790824028,0.18391141717841533,0.254810254426627,0.18391141717841533,0.36931090448637094,2.3452866902285905,0.6062808758329494,0.3011488166696212,1.2797111548412214,2.088833108363494,1.404856290131458,0.9369680850132093
2,702
Sterol binding
8
15
2.701929
0.006894
O15118,Q9H4L5,P61916,P30536,P21796,O75477,P45880,Q14108
Functions
GO Molecular function
msigdb_gomf
74,381,240,114,23,313,26,30
74,313,2094,1920,23,853,1772,114,26,240,30,2362,1875,428,381
2.3553210205573603,0.9000909263071639,-0.540732380985242,-0.4223492971351874,3.300030759770216,0.2313650943574053,-0.308138168176809,1.9115709631930478,3.2819030749164693,1.1310694730368478,3.1093432588488037,-0.7910150544529415,-0.36473682773465654,0.687750303214672,0.7668911001385372
2,702
Endoplasmic reticulum to golgi vesicle mediated transport
13
62
2.698876
0.006957
Q6NUQ1,Q12907,Q9Y3B3,Q15363,Q9Y282,P24390,O95249,Q9BVK6,O95487,Q9P2W9,Q96PC5,P49755,Q7Z7H5
Processes and pathways
GO Biological process
msigdb_gobp
160,221,68,37,6,7,200,205,359,116,253,378,191
1033,1916,1632,1335,1586,1148,1338,1392,1340,1073,500,200,1712,1589,359,920,7,1442,1445,1648,378,622,1602,1727,1854,2380,763,686,739,221,452,1210,37,1571,2142,1260,160,1053,191,1742,663,1825,905,693,805,253,205,1064,1026,589,1472,116,1426,2682,1703,6,2611,1331,68,1583,393,958
0.1112864967658255,-0.4223492971351874,-0.22508051495738804,-0.06526800225829026,-0.19787205833249796,0.036868377335003144,-0.06526800225829026,-0.09134055376869563,-0.06526800225829026,0.08668311743058034,0.5855369618145146,1.3115908775571128,-0.2802102847132027,-0.19787205833249796,0.8056207329272186,0.18391141717841533,3.630300382746048,-0.1176342396375531,-0.1176342396375531,-0.22508051495738804,0.7668911001385372,0.4359099189969065,-0.19787205833249796,-0.2802102847132027,-0.36473682773465654,-0.8236504561955251,0.3011488166696212,0.36931090448637094,0.3240467416918007,1.1982044600111101,0.6473133664185765,0.011651732815977752,2.9694470635904917,-0.17089694126863775,-0.5710083209352036,-0.01377469592003253,1.581373621216261,0.1112864967658255,1.3741556701287698,-0.2802102847132027,0.39168144268614885,-0.33631253477906203,0.20773293514525631,0.36931090448637094,0.27807073501123514,1.0795454359625347,1.2957016226393265,0.1112864967658255,0.13569066148578596,0.47946851200506696,-0.1176342396375531,1.8992357988485726,-0.09134055376869563,-3.0494230058693037,-0.25252550560044684,3.8351492091685384,-1.470087388879226,-0.03941367046144973,2.424219700870432,-0.17089694126863775,0.74731846202068,0.18391141717841533
2,702
Ion transport
24
53
2.693295
0.007075
P04920,Q9H0H5,Q93050,P21796,Q8NE01,P45880,P21281,P24539,Q9Y6M7,Q9Y289,Q9C0H2,P51790,Q9Y487,Q9BPX6,Q9H2H9,O95202,P61421,O75964,Q9Y5K8,Q96QD8,Q9Y277,Q8NEW0,P16615,Q15904
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
514,145,151,23,539,26,291,296,305,184,59,198,204,474,210,332,463,94,229,492,237,109,369,505
1836,1673,94,332,891,514,615,1674,1115,369,531,291,2127,23,680,296,1717,968,922,1721,26,2378,198,1683,1816,2688,657,463,1932,1359,505,1364,583,539,691,109,2614,151,2544,492,1179,474,59,145,210,1799,1187,237,184,204,229,1538,305
-0.36473682773465654,-0.25252550560044684,2.1337776504182426,0.8438063884694104,0.20773293514525631,0.5646389006836805,0.4359099189969065,-0.25252550560044684,0.06187795047934465,0.7863246738934979,0.5435848808587928,0.9733415184995973,-0.5710083209352036,3.300030759770216,0.36931090448637094,0.9552170880450557,-0.2802102847132027,0.15989814001547026,0.18391141717841533,-0.2802102847132027,3.2819030749164693,-0.8236504561955251,1.3273799247937976,-0.25252550560044684,-0.33631253477906203,-4.476245528731529,0.39168144268614885,0.6268724257185203,-0.4223492971351874,-0.06526800225829026,0.5855369618145146,-0.06526800225829026,0.47946851200506696,0.5435848808587928,0.36931090448637094,1.9602443238318379,-1.5096459874254489,1.6374471135787276,-1.1681714201941449,0.6062808758329494,0.036868377335003144,0.6268724257185203,2.4814715373825837,1.6649938710643004,1.2797111548412214,-0.308138168176809,0.036868377335003144,1.148018452189637,1.404856290131458,1.3115908775571128,1.1815848149569044,-0.14415202790824028,0.9369680850132093
2,702
Abnormal tissue metabolite concentration
6
12
2.686822
0.007214
P40855,O75381,P07602,P06865,P17900,P06280
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
226,345,11,177,113,215
1337,345,215,177,11,919,113,226,762,1853,365,1065
-0.06526800225829026,0.8247808034059452,1.247422490494699,1.435179083173316,3.503168251453378,0.18391141717841533,1.9115709631930478,1.1815848149569044,0.3011488166696212,-0.36473682773465654,0.8056207329272186,0.1112864967658255
2,702
Protease
23
104
2.685323
0.007246
Q13510,P42785,Q9NZ08,Q8NHP8,Q5BJF2,P55786,Q9H3G5,P07384,Q5JRX3,O75844,Q9UIQ6,Q8N2K0,P10619,P67812,P52888,O14773,Q9BYT8,Q92643,P42892,Q9HB40,Q99797,Q8TCT9,Q8TCT8
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
134,8,137,144,21,157,38,42,182,57,58,188,63,72,73,199,92,220,95,96,108,244,115
1280,1837,2262,199,1235,561,890,2600,57,1153,333,42,1550,63,1808,2644,1591,2413,964,2587,1487,2009,2467,2010,2468,2701,2012,1401,8,95,1723,2469,397,2133,2649,1448,73,1891,1256,2136,2300,157,1203,1406,973,72,1305,2512,1129,1130,134,453,1047,2141,1414,1737,2561,2226,1937,21,182,1895,523,2551,2527,1089,1519,188,144,2231,440,115,244,220,264,1139,1790,875,1660,745,316,2156,746,2475,1945,1268,2593,1830,108,92,38,781,96,1954,909,137,1956,509,2121,58,1668,820,2123,2089
-0.03941367046144973,-0.36473682773465654,-0.6949533822984102,1.3115908775571128,-0.01377469592003253,0.5010015722710037,0.20773293514525631,-1.4309487853394973,2.5094973738711897,0.036868377335003144,0.8438063884694104,2.849109236264797,-0.17089694126863775,2.4530486238043636,-0.33631253477906203,-1.9299894948150549,-0.19787205833249796,-0.8898717216903321,0.15989814001547026,-1.353903802647287,-0.14415202790824028,-0.4810044712723359,-0.9916536280362304,-0.4810044712723359,-0.9916536280362304,-7.296535538848486,-0.4810044712723359,-0.09134055376869563,3.5552821414043194,2.1337776504182426,-0.2802102847132027,-0.9916536280362304,0.7276051859633127,-0.5710083209352036,-1.9746786799606038,-0.1176342396375531,2.3949755597742,-0.3934145562501481,-0.01377469592003253,-0.5710083209352036,-0.7266710972825526,1.5955163931080725,0.011651732815977752,-0.09134055376869563,0.15989814001547026,2.404770322309479,-0.03941367046144973,-1.0964994453628252,0.06187795047934465,0.06187795047934465,1.7191369886638892,0.6473133664185765,0.1112864967658255,-0.5710083209352036,-0.09134055376869563,-0.2802102847132027,-1.241316825230039,-0.6324042683431318,-0.4223492971351874,3.3298095398885463,1.404856290131458,-0.3934145562501481,0.5646389006836805,-1.2045569767363151,-1.1321541889327764,0.08668311743058034,-0.14415202790824028,1.3895536705247618,1.6649938710643004,-0.6324042683431318,0.6676054254045067,1.9115709631930478,1.1140084276296076,1.2147165622569294,1.0621410964140288,0.06187795047934465,-0.308138168176809,0.2313650943574053,-0.22508051495738804,0.3240467416918007,0.9000909263071639,-0.5710083209352036,0.3240467416918007,-0.9916536280362304,-0.4223492971351874,-0.01377469592003253,-1.353903802647287,-0.33631253477906203,1.9960644529824567,2.1559035701841203,2.9694470635904917,0.3011488166696212,2.1337776504182426,-0.4223492971351874,0.20773293514525631,1.7191369886638892,-0.4223492971351874,0.5855369618145146,-0.540732380985242,2.500199007739095,-0.22508051495738804,0.27807073501123514,-0.540732380985242,-0.5107324113409443
2,702
Protein localization
26
68
2.680433
0.007353
Q9NS69,Q99595,O95169,O00116,P12236,P21796,Q15388,O43808,Q9UJS0,P46379,Q13505,Q9NX63,Q8N4H5,Q5JRX3,Q13190,O14925,Q9Y512,P09601,P51648,Q8TB36,P40855,Q9BY49,O75381,P50402,Q9Y5J7,O15254
Processes and pathways
Reactome Pathways
msigdb_reactome
0,1,259,382,267,23,413,283,429,168,46,311,52,182,452,206,343,211,219,352,226,228,345,243,254,252
382,206,789,252,674,1337,499,283,345,2509,700,2600,1962,594,2199,758,259,891,1115,893,2575,211,2450,794,267,2413,23,1772,1717,617,2658,2211,226,168,243,762,219,1853,2559,1168,1129,864,452,46,662,413,1013,182,2680,52,2150,352,1791,1,2309,1058,228,1144,476,0,311,1472,429,1065,2462,343,254,650
0.74731846202068,1.2797111548412214,0.27807073501123514,1.0795454359625347,0.36931090448637094,-0.06526800225829026,0.5855369618145146,0.9913427102790784,0.8247808034059452,-1.0964994453628252,0.3467667149096307,-1.4309487853394973,-0.4515446964616516,0.45777194879673416,-0.6324042683431318,0.3011488166696212,1.0621410964140288,0.20773293514525631,0.06187795047934465,0.20773293514525631,-1.315983932120922,1.2636184551493796,-0.957392920200188,0.27807073501123514,1.044619903415622,-0.8898717216903321,3.300030759770216,-0.308138168176809,-0.2802102847132027,0.4359099189969065,-2.1587106730993626,-0.6324042683431318,1.1815848149569044,1.5239522688610696,1.1140084276296076,0.3011488166696212,1.2311222135057562,-0.36473682773465654,-1.241316825230039,0.036868377335003144,0.06187795047934465,0.2313650943574053,0.6473133664185765,2.753410498029949,0.39168144268614885,0.7077496739843829,0.13569066148578596,1.404856290131458,-3.0494230058693037,2.617799486981324,-0.5710083209352036,0.8247808034059452,-0.308138168176809,4.159262994962356,-0.7266710972825526,0.1112864967658255,1.1815848149569044,0.06187795047934465,0.6268724257185203,4.4345567444728164,0.9185931557162074,-0.1176342396375531,0.687750303214672,0.1112864967658255,-0.957392920200188,0.8438063884694104,1.0795454359625347,0.4138804266239855
2,702
Amyloid precursor protein metabolic process
6
14
2.676943
0.00743
O95197,Q15392,P62942,Q9NQC3,P49755,Q92542
Processes and pathways
GO Biological process
msigdb_gobp
33,49,83,88,378,222
33,1680,378,397,83,714,974,867,49,222,605,1829,88,1833
3.082238226873909,-0.25252550560044684,0.7668911001385372,0.7276051859633127,2.2632150164335987,0.3467667149096307,0.15989814001547026,0.2313650943574053,2.71205420662372,1.1982044600111101,0.45777194879673416,-0.33631253477906203,2.188669927046933,-0.33631253477906203
2,702
Outer mitochondrial membrane protein complex
8
16
2.668195
0.007626
Q9NS69,Q9BUR5,Q13505,Q9Y512,Q9NX63,Q8N4H5,Q8IWA4,Q9NVH1
Localization
GO Cellular component
msigdb_gocc
0,340,46,343,311,52,373,355
700,758,891,2211,46,413,568,718,944,373,52,340,0,355,311,343
0.3467667149096307,0.3011488166696212,0.20773293514525631,-0.6324042683431318,2.753410498029949,0.7077496739843829,0.5010015722710037,0.3467667149096307,0.18391141717841533,0.7863246738934979,2.617799486981324,0.8438063884694104,4.4345567444728164,0.8247808034059452,0.9185931557162074,0.8438063884694104
2,702
Cholesterol binding
8
12
2.663242
0.007739
O15118,Q9H4L5,P61916,P30536,P21796,O75477,P45880,Q14108
Functions
GO Molecular function
msigdb_gomf
74,381,240,114,23,313,26,30
74,313,2094,1920,23,1772,114,26,240,30,428,381
2.3553210205573603,0.9000909263071639,-0.540732380985242,-0.4223492971351874,3.300030759770216,-0.308138168176809,1.9115709631930478,3.2819030749164693,1.1310694730368478,3.1093432588488037,0.687750303214672,0.7668911001385372
2,702
Abnormal circulating lipid concentration
29
69
2.662814
0.007749
O95470,P07602,Q4G0N4,P42858,Q13045,Q9UJS0,Q14739,P23786,O75648,Q15392,Q9UBM7,O43772,O75844,O14802,P49748,Q15800,P38571,Q9Y285,P37268,P28070,P06280,Q9BV10,P40855,O75381,Q9NZJ7,P61916,Q15904,P50402,Q16836
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
133,11,271,532,425,429,298,169,547,49,445,56,57,559,564,67,449,477,579,207,215,353,226,345,365,240,505,243,506
559,848,2532,56,345,700,547,57,917,133,1036,215,1116,11,1676,2618,2523,1846,169,207,1556,1597,831,2658,579,449,226,2129,532,2132,1648,564,243,762,2299,1853,1256,1650,796,240,1258,1977,711,1168,1043,425,1654,298,976,49,799,67,505,506,271,2570,1092,693,813,353,1423,608,365,445,1958,429,477,753,754
0.5010015722710037,0.2313650943574053,-1.1681714201941449,2.5187525853416863,0.8247808034059452,0.3467667149096307,0.5223730615720535,2.5094973738711897,0.18391141717841533,1.7191369886638892,0.1112864967658255,1.247422490494699,0.06187795047934465,3.503168251453378,-0.25252550560044684,-1.54963172247134,-1.1321541889327764,-0.36473682773465654,1.509380323825773,1.2797111548412214,-0.17089694126863775,-0.19787205833249796,0.254810254426627,-2.1587106730993626,0.47946851200506696,0.6473133664185765,1.1815848149569044,-0.5710083209352036,0.5435848808587928,-0.5710083209352036,-0.22508051495738804,0.5010015722710037,1.1140084276296076,0.3011488166696212,-0.7266710972825526,-0.36473682773465654,-0.01377469592003253,-0.22508051495738804,0.27807073501123514,1.1310694730368478,-0.01377469592003253,-0.4515446964616516,0.3467667149096307,0.036868377335003144,0.1112864967658255,0.687750303214672,-0.22508051495738804,0.9552170880450557,0.15989814001547026,2.71205420662372,0.27807073501123514,2.433875016635886,0.5855369618145146,0.5855369618145146,1.026980616676179,-1.2784570650664284,0.08668311743058034,0.36931090448637094,0.27807073501123514,0.8247808034059452,-0.09134055376869563,0.45777194879673416,0.8056207329272186,0.6676054254045067,-0.4223492971351874,0.687750303214672,0.6268724257185203,0.3240467416918007,0.3240467416918007
2,702
Copi dependent golgi to er retrograde traffic
11
45
2.644751
0.008175
Q6NUQ1,Q9Y3B3,Q15363,P24390,O15260,P04350,Q9BVK6,Q9H0H5,Q9P2W9,Q9BVA1,P49755
Processes and pathways
Reactome Pathways
msigdb_reactome
160,68,37,7,140,300,205,145,116,380,378
1539,1916,140,1586,1340,1394,993,300,920,7,1348,1442,1852,1445,378,1002,1602,1727,1974,623,739,464,797,1206,2180,1933,599,2064,37,160,1615,2030,905,2363,908,670,380,205,2517,145,116,1426,68,1104,393
-0.17089694126863775,-0.4223492971351874,1.692221906453172,-0.19787205833249796,-0.06526800225829026,-0.09134055376869563,0.13569066148578596,0.9369680850132093,0.18391141717841533,3.630300382746048,-0.06526800225829026,-0.1176342396375531,-0.36473682773465654,-0.1176342396375531,0.7668911001385372,0.13569066148578596,-0.19787205833249796,-0.2802102847132027,-0.4515446964616516,0.4359099189969065,0.3240467416918007,0.6268724257185203,0.27807073501123514,0.011651732815977752,-0.6015642502581877,-0.4223492971351874,0.45777194879673416,-0.5107324113409443,2.9694470635904917,1.581373621216261,-0.19787205833249796,-0.4810044712723359,0.20773293514525631,-0.7910150544529415,0.20773293514525631,0.39168144268614885,0.7668911001385372,1.2957016226393265,-1.0964994453628252,1.6649938710643004,1.8992357988485726,-0.09134055376869563,2.424219700870432,0.08668311743058034,0.74731846202068
2,702
Endocytic vesicle membrane
12
33
2.631279
0.008506
Q15907,P11279,Q8WTV0,Q9Y487,Q5KU26,P10321,P20645,P02786,Q93050,P11717,P61421,Q14108
Localization
GO Cellular component
msigdb_gocc
349,318,69,204,170,419,175,333,151,457,463,30
1708,1340,1769,791,333,1548,419,318,457,1809,175,1848,1163,1078,1405,2058,928,463,2014,1127,1977,536,1782,865,30,601,349,170,69,151,1266,1373,204
-0.2802102847132027,-0.06526800225829026,-0.308138168176809,0.27807073501123514,0.8438063884694104,-0.17089694126863775,0.687750303214672,0.881460002398148,0.6268724257185203,-0.33631253477906203,1.4651313202975424,-0.36473682773465654,0.036868377335003144,0.08668311743058034,-0.09134055376869563,-0.5107324113409443,0.18391141717841533,0.6268724257185203,-0.4810044712723359,0.06187795047934465,-0.4515446964616516,0.5435848808587928,-0.308138168176809,0.2313650943574053,3.1093432588488037,0.45777194879673416,0.8247808034059452,1.509380323825773,2.414518252119156,1.6374471135787276,-0.01377469592003253,-0.06526800225829026,1.3115908775571128
2,702
Glycosyl compound catabolic process
6
10
2.618435
0.008833
P08236,P00813,Q13126,P36639,P06280,P04062
Processes and pathways
GO Biological process
msigdb_gobp
261,225,4,105,215,125
2319,225,125,1114,215,261,105,4,281,881
-0.7586901436735312,1.1815848149569044,1.8365297753474792,0.06187795047934465,1.247422490494699,1.0621410964140288,2.0774498833224193,3.929611495114198,1.0092219778652174,0.2313650943574053
2,702
Ectrodactyly
8
14
2.609168
0.009076
P48449,P07196,Q9UBM7,Q6DKJ4,O95202,Q99720,Q9Y6X9,Q8TB36
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
130,360,445,372,332,22,255,352
332,1154,2320,360,130,1853,2021,372,352,1219,22,476,445,255
0.8438063884694104,0.036868377335003144,-0.7586901436735312,0.8056207329272186,1.7850921167036022,-0.36473682773465654,-0.4810044712723359,0.7863246738934979,0.8247808034059452,0.011651732815977752,3.3179623931981417,0.6268724257185203,0.6676054254045067,1.0795454359625347
2,702
ER-Golgi transport
9
49
2.604332
0.009205
Q6NUQ1,O95197,Q15363,Q9Y282,P24390,O95249,O95487,Q9P2W9,P49755
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
160,33,37,6,7,200,359,116,378
1916,1632,1335,1586,1148,1338,1340,1073,500,33,200,1589,359,920,7,1442,1445,1648,378,622,1602,1727,1854,1974,763,686,623,739,1933,1210,37,1571,2142,1260,160,1053,1742,2030,1825,693,805,908,1064,589,116,1426,6,2611,393
-0.4223492971351874,-0.22508051495738804,-0.06526800225829026,-0.19787205833249796,0.036868377335003144,-0.06526800225829026,-0.06526800225829026,0.08668311743058034,0.5855369618145146,3.082238226873909,1.3115908775571128,-0.19787205833249796,0.8056207329272186,0.18391141717841533,3.630300382746048,-0.1176342396375531,-0.1176342396375531,-0.22508051495738804,0.7668911001385372,0.4359099189969065,-0.19787205833249796,-0.2802102847132027,-0.36473682773465654,-0.4515446964616516,0.3011488166696212,0.36931090448637094,0.4359099189969065,0.3240467416918007,-0.4223492971351874,0.011651732815977752,2.9694470635904917,-0.17089694126863775,-0.5710083209352036,-0.01377469592003253,1.581373621216261,0.1112864967658255,-0.2802102847132027,-0.4810044712723359,-0.33631253477906203,0.36931090448637094,0.27807073501123514,0.20773293514525631,0.1112864967658255,0.47946851200506696,1.8992357988485726,-0.09134055376869563,3.8351492091685384,-1.470087388879226,0.74731846202068
2,702
Ascites
8
23
2.599375
0.009339
P08236,Q13510,Q01844,O15118,P10644,P61916,P04062,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
261,134,202,74,111,240,125,30
74,1803,2522,1394,125,261,111,656,1592,449,1853,240,2015,1503,535,202,1085,134,30,298,1515,950,754
2.3553210205573603,-0.33631253477906203,-1.1321541889327764,-0.09134055376869563,1.8365297753474792,1.0621410964140288,1.9360399599594456,0.39168144268614885,-0.19787205833249796,0.6473133664185765,-0.36473682773465654,1.1310694730368478,-0.4810044712723359,-0.14415202790824028,0.5435848808587928,1.3115908775571128,0.08668311743058034,1.7191369886638892,3.1093432588488037,0.9552170880450557,-0.14415202790824028,0.18391141717841533,0.3240467416918007
2,702
Nucleobase containing compound transmembrane transporter activity
9
14
2.598934
0.009351
P12236,O15439,Q8TB61,P05141,Q6NUK1,O43808,Q9H2D1,O00400,Q9HC21
Functions
GO Molecular function
msigdb_gomf
267,479,181,274,414,283,60,155,323
2044,155,479,283,274,794,267,856,832,414,181,557,60,323
-0.5107324113409443,1.5955163931080725,0.6062808758329494,0.9913427102790784,1.0092219778652174,0.27807073501123514,1.044619903415622,0.2313650943574053,0.254810254426627,0.7077496739843829,1.4200644560622815,0.5223730615720535,2.4814715373825837,0.881460002398148
2,702
Amyloid precursor protein catabolic process
6
13
2.594982
0.00946
O95197,Q15392,P62942,Q9NQC3,P49755,Q92542
Processes and pathways
GO Biological process
msigdb_gobp
33,49,83,88,378,222
33,1680,378,397,83,714,974,867,49,222,605,1829,88
3.082238226873909,-0.25252550560044684,0.7668911001385372,0.7276051859633127,2.2632150164335987,0.3467667149096307,0.15989814001547026,0.2313650943574053,2.71205420662372,1.1982044600111101,0.45777194879673416,-0.33631253477906203,2.188669927046933
2,702
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
6
21
2.568407
0.010217
Q6NUQ1,Q12907,Q9Y282,P24390,Q9P2W9,P48739
Processes and pathways
GO Biological process
msigdb_gobp
160,221,6,7,116,314
1916,1234,1340,920,7,1442,532,1445,314,378,1727,623,221,1933,160,874,1825,905,116,1426,6
-0.4223492971351874,-0.01377469592003253,-0.06526800225829026,0.18391141717841533,3.630300382746048,-0.1176342396375531,0.5435848808587928,-0.1176342396375531,0.9000909263071639,0.7668911001385372,-0.2802102847132027,0.4359099189969065,1.1982044600111101,-0.4223492971351874,1.581373621216261,0.2313650943574053,-0.33631253477906203,0.20773293514525631,1.8992357988485726,-0.09134055376869563,3.8351492091685384
2,702
Transport to the golgi and subsequent modification
23
69
2.554566
0.010632
Q13561,P24390,Q16706,Q15363,O75935,P04350,Q13190,Q9Y3B3,O95249,Q9BVK6,P68371,Q12907,Q13885,P61923,Q14789,Q14203,O95487,Q9UJW0,Q9BVA1,P49755,O15020,Q96PC5,Q9Y678
Processes and pathways
Reactome Pathways
msigdb_reactome
387,7,278,37,418,300,452,68,200,205,464,221,599,623,628,486,359,510,380,378,376,253,393
1033,1916,376,1632,1335,914,1148,1338,1340,418,1073,200,1589,359,1114,300,920,7,1442,1852,2271,1161,1445,1648,378,1601,1602,1727,1854,1974,763,1165,623,739,464,710,221,1567,452,2420,387,626,599,486,798,628,37,1571,278,800,1260,1742,2030,1825,905,693,253,908,670,380,205,1064,2602,1426,510,68,393,1387,958
0.1112864967658255,-0.4223492971351874,0.7668911001385372,-0.22508051495738804,-0.06526800225829026,0.18391141717841533,0.036868377335003144,-0.06526800225829026,-0.06526800225829026,0.687750303214672,0.08668311743058034,1.3115908775571128,-0.19787205833249796,0.8056207329272186,0.06187795047934465,0.9369680850132093,0.18391141717841533,3.630300382746048,-0.1176342396375531,-0.36473682773465654,-0.6949533822984102,0.036868377335003144,-0.1176342396375531,-0.22508051495738804,0.7668911001385372,-0.19787205833249796,-0.19787205833249796,-0.2802102847132027,-0.36473682773465654,-0.4515446964616516,0.3011488166696212,0.036868377335003144,0.4359099189969065,0.3240467416918007,0.6268724257185203,0.3467667149096307,1.1982044600111101,-0.17089694126863775,0.6473133664185765,-0.8898717216903321,0.74731846202068,0.4359099189969065,0.45777194879673416,0.6062808758329494,0.27807073501123514,0.4359099189969065,2.9694470635904917,-0.17089694126863775,1.0092219778652174,0.27807073501123514,-0.01377469592003253,-0.2802102847132027,-0.4810044712723359,-0.33631253477906203,0.20773293514525631,0.36931090448637094,1.0795454359625347,0.20773293514525631,0.39168144268614885,0.7668911001385372,1.2957016226393265,0.1112864967658255,-1.4309487853394973,-0.09134055376869563,0.5855369618145146,2.424219700870432,0.74731846202068,-0.06526800225829026,0.18391141717841533
2,702
Nucleotide transmembrane transporter activity
9
12
2.552652
0.010691
P12236,O15439,Q8TB61,P05141,Q6NUK1,O43808,Q9H2D1,O00400,Q9HC21
Functions
GO Molecular function
msigdb_gomf
267,479,181,274,414,283,60,155,323
155,479,283,274,794,267,856,414,181,557,60,323
1.5955163931080725,0.6062808758329494,0.9913427102790784,1.0092219778652174,0.27807073501123514,1.044619903415622,0.2313650943574053,0.7077496739843829,1.4200644560622815,0.5223730615720535,2.4814715373825837,0.881460002398148
2,702
Organophosphate ester transmembrane transporter activity
9
12
2.552652
0.010691
P12236,O15439,Q8TB61,P05141,Q6NUK1,O43808,Q9H2D1,O00400,Q9HC21
Functions
GO Molecular function
msigdb_gomf
267,479,181,274,414,283,60,155,323
155,479,283,274,794,267,856,414,181,557,60,323
1.5955163931080725,0.6062808758329494,0.9913427102790784,1.0092219778652174,0.27807073501123514,1.044619903415622,0.2313650943574053,0.7077496739843829,1.4200644560622815,0.5223730615720535,2.4814715373825837,0.881460002398148
2,702
Exopeptidase activity
9
28
2.534149
0.011272
Q9HB40,Q9H3G5,P42785,Q9NZ08,O14773,O75844,Q9UIQ6,P55786,P10619
Functions
GO Molecular function
msigdb_gomf
96,38,8,137,199,57,58,157,63
199,57,562,333,2411,63,2644,2467,2010,1350,8,157,2246,453,1089,1519,264,806,2475,1374,38,1949,96,1992,2118,909,137,58
1.3115908775571128,2.5094973738711897,0.5010015722710037,0.8438063884694104,-0.8898717216903321,2.4530486238043636,-1.9299894948150549,-0.9916536280362304,-0.4810044712723359,-0.06526800225829026,3.5552821414043194,1.5955163931080725,-0.6635325569459647,0.6473133664185765,0.08668311743058034,-0.14415202790824028,1.0621410964140288,0.27807073501123514,-0.9916536280362304,-0.06526800225829026,2.9694470635904917,-0.4223492971351874,2.1337776504182426,-0.4515446964616516,-0.540732380985242,0.20773293514525631,1.7191369886638892,2.500199007739095
2,702
Carbohydrate derivative transport
13
18
2.519151
0.011764
Q8WTV0,Q9NZJ7,P12236,P07602,P61916,O15439,Q8TB61,Q08722,P05141,Q6NUK1,O43808,O00400,Q9HC21
Processes and pathways
GO Biological process
msigdb_gobp
69,365,267,11,240,479,181,411,274,414,283,155,323
2044,155,479,283,274,11,794,267,856,240,411,414,181,2614,69,557,323,365
-0.5107324113409443,1.5955163931080725,0.6062808758329494,0.9913427102790784,1.0092219778652174,3.503168251453378,0.27807073501123514,1.044619903415622,0.2313650943574053,1.1310694730368478,0.7077496739843829,0.7077496739843829,1.4200644560622815,-1.5096459874254489,2.414518252119156,0.5223730615720535,0.881460002398148,0.8056207329272186
2,702
Inner mitochondrial membrane organization
10
21
2.51763
0.011815
Q9P0J0,Q13505,Q9H3K2,Q9BUR5,Q9Y512,O60313,Q9NX63,O95202,P17152,Q9Y5J7
Processes and pathways
GO Biological process
msigdb_gobp
171,46,303,340,343,239,311,332,276,254
239,700,758,332,276,2211,46,568,869,718,944,665,340,303,355,311,171,820,343,254,650
1.1310694730368478,0.3467667149096307,0.3011488166696212,0.8438063884694104,1.0092219778652174,-0.6324042683431318,2.753410498029949,0.5010015722710037,0.2313650943574053,0.3467667149096307,0.18391141717841533,0.39168144268614885,0.8438063884694104,0.9369680850132093,0.8247808034059452,0.9185931557162074,1.509380323825773,0.27807073501123514,0.8438063884694104,1.0795454359625347,0.4138804266239855
2,702
Golgi apparatus
87
262
2.506019
0.01221
Q9Y282,P24390,O00203,P80303,O43823,P62993,Q5VW38,P16278,Q9NTJ5,Q12846,P42858,Q9UQB8,Q14108,O14828,O95197,Q15363,Q6NTF9,Q15392,O14976,Q02818,Q9NR31,Q9H8Y8,Q9Y3B3,O15118,O14578,O43505,Q8N4V1,Q9UPN3,Q9NP72,P50897,Q7Z5K2,Q15334,O00461,Q9NPR9,P61923,Q8NBN3,Q14789,Q8NEW0,P51572,P42345,Q9P2W9,Q8N2H4,P04062,O15260,Q8IV08,Q93050,O00400,P35613,P20645,Q6Y7W6,Q8TB61,Q7Z7H5,P51790,O95249,O14773,Q9BVK6,P06280,Q9BTU6,Q92542,Q12907,P53367,O43852,Q16706,Q9NX62,Q6NUQ4,P48739,Q9BUR5,Q9NX40,Q92896,Q15691,P49755,Q9Y678,Q99805,P40616,O95721,P52292,P49768,Q9H7Z7,O75503,P10321,Q86Y82,Q13190,O00429,Q8NF37,P11717,Q96KC2,O95070
Localization
GO Cellular component
msigdb_gocc
6,7,512,9,513,518,16,19,543,536,532,31,30,528,33,37,555,49,560,62,589,588,68,74,577,78,79,610,607,82,87,601,90,97,623,101,628,109,622,619,116,117,125,140,147,151,155,159,175,180,181,191,198,200,199,205,215,217,222,221,247,265,278,304,309,314,340,356,364,371,378,393,390,386,384,398,397,416,406,419,438,452,447,471,457,491,500
2044,512,2584,155,447,2463,90,577,1916,2197,846,1034,912,199,528,560,1632,74,913,888,1234,140,1335,2169,78,1148,1236,1070,513,265,2630,730,1338,1766,1340,406,1481,1840,1482,500,33,1394,200,1712,2397,2200,962,384,791,125,1548,615,215,1240,1715,1243,759,419,1882,457,19,1845,920,175,2051,1486,853,7,1292,2172,1848,2498,2467,1596,1398,1158,1442,159,1159,2209,1646,386,619,532,1852,1445,314,1648,706,378,397,1446,762,1163,1200,82,1078,1405,2104,622,198,398,971,247,1602,1727,1040,1500,928,686,1125,623,739,518,2275,9,1932,1127,1977,1082,62,2669,688,1043,1084,1820,1129,536,1130,221,1567,452,714,974,1131,2223,1210,865,30,1569,643,1860,628,1510,1049,601,37,49,1571,371,278,2110,836,16,942,555,309,1938,2333,1611,180,945,2286,1518,1053,2251,87,1463,191,1521,438,1742,147,838,802,2253,117,79,2030,744,101,1523,109,471,181,874,2072,1825,1903,905,222,947,2255,364,2155,151,1220,2187,805,491,906,1221,1179,2362,1946,390,1375,2459,217,813,340,205,2310,748,1875,780,987,2117,879,1321,416,588,1026,607,97,1755,589,543,356,304,1186,1833,1472,1030,116,1426,2431,2531,2194,2085,2582,1187,1278,751,725,610,1533,31,955,6,1427,2611,1581,2393,1032,1331,68,1537,1670,2447,393,958
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0.13569066148578596,-0.03941367046144973,2.424219700870432,-0.14415202790824028,-0.22508051495738804,-0.9234673291200788,0.74731846202068,0.18391141717841533
2,702
Hyperlipidemia
9
24
2.501257
0.012375
Q13045,O95470,Q9UJS0,P38571,P23786,P28070,P50402,P06280,O75844
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
425,133,429,449,169,207,243,215,57
559,848,700,57,133,1036,215,1116,1846,169,207,1556,831,449,1648,243,1256,425,1654,1092,693,813,429,477
0.5010015722710037,0.2313650943574053,0.3467667149096307,2.5094973738711897,1.7191369886638892,0.1112864967658255,1.247422490494699,0.06187795047934465,-0.36473682773465654,1.509380323825773,1.2797111548412214,-0.17089694126863775,0.254810254426627,0.6473133664185765,-0.22508051495738804,1.1140084276296076,-0.01377469592003253,0.687750303214672,-0.22508051495738804,0.08668311743058034,0.36931090448637094,0.27807073501123514,0.687750303214672,0.6268724257185203
2,702
Cation transmembrane transport
32
104
2.500261
0.01241
Q9Y376,Q9HD20,Q70HW3,P62258,P13073,P49768,P21796,P05141,O00400,P00403,P21281,P24539,P07384,Q9Y6M7,Q9H0U3,Q9UJZ1,O43772,Q8IWX8,Q9HC21,Q7KZN9,P51790,Q96ES6,Q9BPX6,Q96NB2,Q8N4V1,P62942,O95202,Q9UDW1,O75964,Q8NEW0,P16615,P78417
Processes and pathways
GO Biological process
msigdb_gobp
392,136,14,400,269,397,23,274,155,407,291,296,42,305,443,446,56,187,323,195,198,76,474,473,79,83,332,98,94,109,369,249
155,1067,848,56,1286,757,2667,2600,1673,94,332,407,615,1674,274,2201,1115,1434,42,1920,1435,893,1639,1677,794,269,369,1245,2557,531,1249,291,2127,2051,23,680,296,1717,1680,1720,2524,1294,2468,968,922,1721,532,1444,2378,397,1163,198,1164,1816,2688,657,463,580,400,83,249,1932,933,712,863,1567,936,1654,2581,601,940,1364,14,195,187,2571,79,691,109,665,804,2544,76,1371,473,1221,2593,525,474,779,443,1181,323,136,2441,98,2431,1799,446,1187,392,820,885,305
1.5955163931080725,0.08668311743058034,0.2313650943574053,2.5187525853416863,-0.03941367046144973,0.3011488166696212,-2.302553966333245,-1.4309487853394973,-0.25252550560044684,2.1337776504182426,0.8438063884694104,0.7077496739843829,0.4359099189969065,-0.25252550560044684,1.0092219778652174,-0.6324042683431318,0.06187795047934465,-0.1176342396375531,2.849109236264797,-0.4223492971351874,-0.1176342396375531,0.20773293514525631,-0.22508051495738804,-0.25252550560044684,0.27807073501123514,1.026980616676179,0.7863246738934979,-0.01377469592003253,-1.241316825230039,0.5435848808587928,-0.01377469592003253,0.9733415184995973,-0.5710083209352036,-0.5107324113409443,3.300030759770216,0.36931090448637094,0.9552170880450557,-0.2802102847132027,-0.25252550560044684,-0.2802102847132027,-1.1321541889327764,-0.03941367046144973,-0.9916536280362304,0.15989814001547026,0.18391141717841533,-0.2802102847132027,0.5435848808587928,-0.1176342396375531,-0.8236504561955251,0.7276051859633127,0.036868377335003144,1.3273799247937976,0.036868377335003144,-0.33631253477906203,-4.476245528731529,0.39168144268614885,0.6268724257185203,0.47946851200506696,0.7276051859633127,2.2632150164335987,1.0968341446394454,-0.4223492971351874,0.18391141717841533,0.3467667149096307,0.2313650943574053,-0.17089694126863775,0.18391141717841533,-0.22508051495738804,-1.315983932120922,0.45777194879673416,0.18391141717841533,-0.06526800225829026,3.4216157303597954,1.3430697559709033,1.3895536705247618,-1.2784570650664284,2.3250705886421623,0.36931090448637094,1.9602443238318379,0.39168144268614885,0.27807073501123514,-1.1681714201941449,2.3452866902285905,-0.06526800225829026,0.6268724257185203,0.011651732815977752,-1.353903802647287,0.5646389006836805,0.6268724257185203,0.3011488166696212,0.6676054254045067,0.036868377335003144,0.881460002398148,1.7191369886638892,-0.9234673291200788,2.1337776504182426,-0.8898717216903321,-0.308138168176809,0.6676054254045067,0.036868377335003144,0.74731846202068,0.27807073501123514,0.2313650943574053,0.9369680850132093
2,702
Establishment of protein localization
127
449
2.494209
0.012624
Q9NS69,Q99595,Q99623,Q13432,Q9Y282,P24390,Q15058,O00203,P63104,O43823,P57105,Q16822,Q9UPT5,Q9UHB9,Q9H089,Q9H7B4,A6NIH7,Q12846,Q15629,Q14108,O14828,Q9P0I2,Q15363,Q641Q2,P20290,Q9UGP8,Q16850,Q8N4H5,P43307,Q32P28,O95373,Q16543,P10619,Q9UBQ0,Q9NR31,Q9Y3B3,Q9H8Y8,Q8IYI6,P06493,O15118,Q8N4V1,P61619,Q9UPN3,Q9P2E9,P50897,Q9NP72,Q96P70,Q99797,P30536,Q9P2W9,Q8N2H4,Q8TEX9,Q9Y5M8,A0AVF1,Q9HD20,O15260,Q9BTX1,P55786,Q6NUQ1,Q15070,P46379,Q9P0J0,P20645,O15397,Q5JRX3,Q7Z7H5,O95249,Q9BVK6,O14925,Q9BUN8,O60725,Q12907,P40855,Q8TCT9,P50402,O14737,P53367,Q9Y5J7,Q96PC5,Q53EZ4,O95831,Q8NFH4,Q14C86,Q12769,P11279,Q96A33,Q8WUH2,Q9Y512,P02786,O14964,Q8TB36,Q15907,P31946,O75381,Q709C8,O95487,Q92973,P49755,Q9Y678,Q8N1F7,P40616,O95721,P61981,P62258,P52292,P04083,P49768,Q15388,P31749,Q969Q5,Q5J8M3,Q92688,Q86Y82,Q13190,O00429,Q14978,P52294,P55060,Q9Y5X3,Q96KC2,Q15904,Q8WUX9,Q16836,P21359,P12270,O95070,O43765
Processes and pathways
GO Biological process
msigdb_gobp
0,1,525,5,6,7,522,512,519,513,517,537,545,544,541,24,25,536,29,30,528,558,37,554,550,575,50,52,53,569,563,567,63,590,589,68,588,586,578,74,79,580,610,609,82,607,605,108,114,116,117,118,124,132,136,140,154,157,160,167,168,171,175,176,182,191,200,205,206,209,214,221,226,244,243,242,247,254,253,287,290,294,301,308,318,330,338,343,333,331,352,349,346,345,363,359,375,378,393,389,386,384,399,400,398,395,397,413,409,427,426,441,438,452,447,467,461,462,498,491,505,507,506,502,501,500,499
132,25,960,1708,1333,2342,512,2573,2584,1428,612,447,1540,911,2125,1916,2197,242,528,206,331,1069,1632,74,913,888,140,176,728,1335,1586,1035,2567,674,1336,1337,848,1236,499,513,2449,1479,1284,1390,214,653,1338,1339,1287,1071,1392,2092,345,1340,1999,2600,1840,1806,1341,1482,1238,1432,758,654,1769,1073,500,1433,1394,200,563,918,1589,359,1112,962,994,384,791,290,891,1154,2318,1036,333,395,1843,2320,1674,578,824,1196,678,850,2465,1243,759,63,2450,1244,1344,1345,318,501,1155,616,2050,894,1245,2451,1845,1119,920,2322,1248,550,2414,1809,175,2051,502,853,7,1156,1680,1848,703,895,1440,114,1294,1398,829,409,346,1348,1886,830,735,705,1442,1121,2209,1887,1925,2211,2212,386,1851,226,2129,1299,2350,2269,53,1403,168,1852,1445,2132,1648,736,1557,2175,2176,2326,378,397,2013,1162,1446,243,762,1163,82,1972,1559,1600,1078,1405,2104,622,398,461,1202,1891,926,247,1602,1727,2058,1498,1255,1854,1974,462,2380,1561,763,157,517,796,2559,1040,1500,928,1203,1855,686,2595,1125,580,623,1408,399,400,739,1042,930,1729,2014,519,2015,2277,1410,2016,1932,1127,710,712,768,2419,1208,1820,1129,2220,308,536,221,1567,1085,1507,452,2222,934,5,1782,1131,865,1308,30,2224,1132,1569,1048,1259,467,301,1511,2651,522,167,601,37,413,1571,2142,29,1686,2143,505,349,1784,567,537,506,50,569,1013,2110,1687,287,869,426,1260,182,2184,716,836,554,2024,160,363,2680,1213,2552,1689,979,1463,191,1054,438,586,2253,389,117,52,79,2030,1138,630,2150,691,294,1176,1693,352,244,874,2114,118,981,338,1788,664,507,1825,665,1903,1987,905,947,2255,666,441,647,1420,375,2155,1220,805,427,330,1056,1266,776,491,747,1661,1267,605,253,2562,877,1024,2593,1751,1373,1,525,908,108,1222,2036,154,209,205,1094,1058,1904,2310,780,987,2365,2116,541,2117,2311,1579,24,1226,588,1182,1144,1064,136,1026,607,1272,2192,589,1756,0,2391,1954,1185,2078,1145,1381,558,171,2519,2408,2120,609,116,1798,1426,590,1957,844,1911,575,544,2431,882,2530,2084,2085,2292,1278,2165,1232,751,610,545,1534,1065,6,1581,1032,1331,68,1535,1537,1385,1104,956,343,254,650,2043,754,124,2447,498,393,2166,958
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2,702
Organelle envelope lumen
13
28
2.472425
0.01342
O95831,P07437,P52888,Q9BPX6,O14925,O60313,Q9HB71,O00584,Q9UJZ1,Q96AY3,Q9BYT8,Q9Y5J7,Q9NR28
Localization
GO Cellular component
msigdb_gocc
290,325,73,474,206,239,212,213,446,415,92,254,324
213,206,239,290,325,457,1595,1159,1350,1726,73,2059,1505,568,869,1419,2503,415,2593,474,92,1664,212,324,446,1535,254,650
1.247422490494699,1.2797111548412214,1.1310694730368478,0.9733415184995973,0.8626989686693847,0.6268724257185203,-0.19787205833249796,0.036868377335003144,-0.06526800225829026,-0.2802102847132027,2.3949755597742,-0.5107324113409443,-0.14415202790824028,0.5010015722710037,0.2313650943574053,-0.09134055376869563,-1.0612014774574168,0.7077496739843829,-1.353903802647287,0.6268724257185203,2.1559035701841203,-0.22508051495738804,1.2636184551493796,0.881460002398148,0.6676054254045067,-0.14415202790824028,1.0795454359625347,0.4138804266239855
2,702
Mitochondrial nucleotide transporter subfamily
6
8
2.471676
0.013448
P12236,Q70HW3,P05141,O43808,Q9H2D1,Q9HC21
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
267,14,274,283,60,323
283,274,794,267,414,14,60,323
0.9913427102790784,1.0092219778652174,0.27807073501123514,1.044619903415622,0.7077496739843829,3.4216157303597954,2.4814715373825837,0.881460002398148
2,702
Mitochondrial transmembrane transport
18
46
2.467463
0.013607
Q99595,O95831,Q9UJZ1,O43772,Q9UJS0,O75964,P24539,Q6P4A7,P12236,P23786,Q9BPX6,O14925,Q9BQT8,O95202,P21796,P05141,Q15388,Q9H2D1
Processes and pathways
GO Biological process
msigdb_gobp
1,290,446,56,429,94,296,41,267,169,474,206,120,332,23,274,413,60
206,674,56,757,2600,594,1673,94,758,332,1112,290,891,274,1115,2450,794,267,23,169,296,1717,968,2378,2688,657,933,413,1013,41,691,2503,665,2544,473,1,474,120,1058,60,1181,1144,429,446,820,885
1.2797111548412214,0.36931090448637094,2.5187525853416863,0.3011488166696212,-1.4309487853394973,0.45777194879673416,-0.25252550560044684,2.1337776504182426,0.3011488166696212,0.8438063884694104,0.06187795047934465,0.9733415184995973,0.20773293514525631,1.0092219778652174,0.06187795047934465,-0.957392920200188,0.27807073501123514,1.044619903415622,3.300030759770216,1.509380323825773,0.9552170880450557,-0.2802102847132027,0.15989814001547026,-0.8236504561955251,-4.476245528731529,0.39168144268614885,0.18391141717841533,0.7077496739843829,0.13569066148578596,2.8568664927325975,0.36931090448637094,-1.0612014774574168,0.39168144268614885,-1.1681714201941449,0.6268724257185203,4.159262994962356,0.6268724257185203,1.8743612216621832,0.1112864967658255,2.4814715373825837,0.036868377335003144,0.06187795047934465,0.687750303214672,0.6676054254045067,0.27807073501123514,0.2313650943574053
2,702
Golgi associated vesicle
7
28
2.465751
0.013673
Q9Y3B3,Q15363,P24390,Q9BVK6,Q8TCT8,P49755,Q9Y678
Localization
GO Cellular component
msigdb_gocc
68,37,7,205,115,378,393
1916,1236,791,1243,759,457,7,1442,2101,1445,378,2104,1602,1727,928,1125,623,1127,1977,37,115,1825,205,1026,1030,1426,68,393
-0.4223492971351874,-0.01377469592003253,0.27807073501123514,-0.01377469592003253,0.3011488166696212,0.6268724257185203,3.630300382746048,-0.1176342396375531,-0.540732380985242,-0.1176342396375531,0.7668911001385372,-0.540732380985242,-0.19787205833249796,-0.2802102847132027,0.18391141717841533,0.06187795047934465,0.4359099189969065,0.06187795047934465,-0.4515446964616516,2.9694470635904917,1.9115709631930478,-0.33631253477906203,1.2957016226393265,0.13569066148578596,0.13569066148578596,-0.09134055376869563,2.424219700870432,0.74731846202068
2,702
Abnormal circulating cholesterol concentration
15
29
2.458434
0.013954
Q13045,Q15800,Q9UJS0,P38571,Q14739,Q9NZJ7,P07602,P37268,P61916,Q15392,Q9UBM7,Q15904,P50402,Q9BV10,P42858
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
425,67,429,449,298,365,11,579,240,49,445,505,243,353,532
700,1036,1116,11,579,449,532,2132,243,2299,796,240,1977,1043,425,1654,298,49,799,67,505,2570,1092,813,353,608,365,445,429
0.3467667149096307,0.1112864967658255,0.06187795047934465,3.503168251453378,0.47946851200506696,0.6473133664185765,0.5435848808587928,-0.5710083209352036,1.1140084276296076,-0.7266710972825526,0.27807073501123514,1.1310694730368478,-0.4515446964616516,0.1112864967658255,0.687750303214672,-0.22508051495738804,0.9552170880450557,2.71205420662372,0.27807073501123514,2.433875016635886,0.5855369618145146,-1.2784570650664284,0.08668311743058034,0.27807073501123514,0.8247808034059452,0.45777194879673416,0.8056207329272186,0.6676054254045067,0.687750303214672
2,702
Protease
21
74
2.455861
0.014055
Q16740,P28072,P42785,Q9NZ08,P55786,Q9H3G5,P07384,Q5JRX3,O75844,Q9UIQ6,P10619,P67812,P52888,O14773,Q9BYT8,Q92643,P42892,Q9HB40,Q99797,Q8TCT8,Q9UPU5
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
128,129,8,137,157,38,42,182,57,58,63,72,73,199,92,220,95,96,108,115,121
1280,2262,199,561,2600,57,562,1153,42,2411,63,2644,2413,129,433,2467,2010,2701,2012,1401,8,95,1723,2469,397,73,1891,2136,2300,157,1203,72,2697,453,2141,1414,1511,128,2110,182,1895,2551,1089,1519,337,115,244,220,1139,1791,1660,316,746,2475,1945,1268,442,2593,1830,108,92,38,1949,781,96,1992,2118,909,137,509,58,121,820,2123
-0.03941367046144973,-0.6949533822984102,1.3115908775571128,0.5010015722710037,-1.4309487853394973,2.5094973738711897,0.5010015722710037,0.036868377335003144,2.849109236264797,-0.8898717216903321,2.4530486238043636,-1.9299894948150549,-0.8898717216903321,1.7850921167036022,0.6676054254045067,-0.9916536280362304,-0.4810044712723359,-7.296535538848486,-0.4810044712723359,-0.09134055376869563,3.5552821414043194,2.1337776504182426,-0.2802102847132027,-0.9916536280362304,0.7276051859633127,2.3949755597742,-0.3934145562501481,-0.5710083209352036,-0.7266710972825526,1.5955163931080725,0.011651732815977752,2.404770322309479,-6.468314273842489,0.6473133664185765,-0.5710083209352036,-0.09134055376869563,-0.14415202790824028,1.7980601075871823,-0.540732380985242,1.404856290131458,-0.3934145562501481,-1.2045569767363151,0.08668311743058034,-0.14415202790824028,0.8438063884694104,1.9115709631930478,1.1140084276296076,1.2147165622569294,0.06187795047934465,-0.308138168176809,-0.22508051495738804,0.9000909263071639,0.3240467416918007,-0.9916536280362304,-0.4223492971351874,-0.01377469592003253,0.6676054254045067,-1.353903802647287,-0.33631253477906203,1.9960644529824567,2.1559035701841203,2.9694470635904917,-0.4223492971351874,0.3011488166696212,2.1337776504182426,-0.4515446964616516,-0.540732380985242,0.20773293514525631,1.7191369886638892,0.5855369618145146,2.500199007739095,1.8743612216621832,0.27807073501123514,-0.540732380985242
2,702
Er to golgi anterograde transport
22
67
2.447452
0.014387
Q13561,P24390,Q15363,O75935,P04350,Q13190,Q9Y3B3,O95249,Q9BVK6,P68371,Q12907,Q13885,P61923,Q14789,Q14203,O95487,Q9UJW0,Q9BVA1,P49755,O15020,Q96PC5,Q9Y678
Processes and pathways
Reactome Pathways
msigdb_reactome
387,7,37,418,300,452,68,200,205,464,221,599,623,628,486,359,510,380,378,376,253,393
1033,1916,376,1632,1335,914,1148,1338,1340,418,1073,200,1589,359,300,920,7,1442,1852,2271,1161,1445,1648,378,1601,1602,1727,1854,1974,763,1165,623,739,464,710,221,1567,452,2420,387,626,599,486,798,628,37,1571,800,1260,1742,2030,1825,905,693,253,908,670,380,205,1064,2602,1426,510,68,393,1387,958
0.1112864967658255,-0.4223492971351874,0.7668911001385372,-0.22508051495738804,-0.06526800225829026,0.18391141717841533,0.036868377335003144,-0.06526800225829026,-0.06526800225829026,0.687750303214672,0.08668311743058034,1.3115908775571128,-0.19787205833249796,0.8056207329272186,0.9369680850132093,0.18391141717841533,3.630300382746048,-0.1176342396375531,-0.36473682773465654,-0.6949533822984102,0.036868377335003144,-0.1176342396375531,-0.22508051495738804,0.7668911001385372,-0.19787205833249796,-0.19787205833249796,-0.2802102847132027,-0.36473682773465654,-0.4515446964616516,0.3011488166696212,0.036868377335003144,0.4359099189969065,0.3240467416918007,0.6268724257185203,0.3467667149096307,1.1982044600111101,-0.17089694126863775,0.6473133664185765,-0.8898717216903321,0.74731846202068,0.4359099189969065,0.45777194879673416,0.6062808758329494,0.27807073501123514,0.4359099189969065,2.9694470635904917,-0.17089694126863775,0.27807073501123514,-0.01377469592003253,-0.2802102847132027,-0.4810044712723359,-0.33631253477906203,0.20773293514525631,0.36931090448637094,1.0795454359625347,0.20773293514525631,0.39168144268614885,0.7668911001385372,1.2957016226393265,0.1112864967658255,-1.4309487853394973,-0.09134055376869563,0.5855369618145146,2.424219700870432,0.74731846202068,-0.06526800225829026,0.18391141717841533
2,702
Organic acid transport
17
41
2.445431
0.014468
Q9UJS0,P08183,Q96QD8,Q9UBX3,Q6P4A7,P23786,Q96NB2,Q9BQT8,O15439,P04083,Q9H2H9,P49768,Q9Y289,O43772,O43808,Q9H2D1,P31749
Processes and pathways
GO Biological process
msigdb_gobp
429,197,492,103,41,169,473,120,479,395,210,397,184,56,283,60,409
479,56,283,594,1238,1112,962,2410,395,2201,1675,197,1435,1882,2004,502,169,617,1849,409,2208,2558,856,397,1498,2453,835,940,2025,41,2614,473,492,120,60,210,1181,103,429,184,885
0.6062808758329494,2.5187525853416863,0.9913427102790784,0.45777194879673416,-0.01377469592003253,0.06187795047934465,0.15989814001547026,-0.8898717216903321,0.7276051859633127,-0.6324042683431318,-0.25252550560044684,1.3273799247937976,-0.1176342396375531,-0.3934145562501481,-0.4810044712723359,0.5855369618145146,1.509380323825773,0.4359099189969065,-0.36473682773465654,0.7077496739843829,-0.6324042683431318,-1.241316825230039,0.2313650943574053,0.7276051859633127,-0.14415202790824028,-0.957392920200188,0.254810254426627,0.18391141717841533,-0.4810044712723359,2.8568664927325975,-1.5096459874254489,0.6268724257185203,0.6062808758329494,1.8743612216621832,2.4814715373825837,1.2797111548412214,0.036868377335003144,2.088833108363494,0.687750303214672,1.404856290131458,0.2313650943574053
2,702
Cholesterol biosynthesis
7
15
2.445391
0.01447
Q15800,P48449,Q14739,Q15392,Q16850,Q9BWD1,Q14534
Processes and pathways
Reactome Pathways
msigdb_reactome
67,130,298,49,50,245,412
595,963,579,130,1819,2139,412,298,1982,49,799,67,50,245,445
0.45777194879673416,0.15989814001547026,0.47946851200506696,1.7850921167036022,-0.33631253477906203,-0.5710083209352036,0.7077496739843829,0.9552170880450557,-0.4515446964616516,2.71205420662372,0.27807073501123514,2.433875016635886,2.71205420662372,1.1140084276296076,0.6676054254045067
2,702
Alzheimers disease
24
74
2.445284
0.014474
P28072,P12236,P49768,P49721,P21796,P05141,P45880,P31749,O95197,P07384,P20618,P04350,Q99436,P60900,P28074,P07437,P28070,P48729,Q9NQC3,P68371,Q92542,Q9Y277,P16615,Q9BVA1
Processes and pathways
WikiPathways
msigdb_wp
129,267,397,20,23,274,26,409,33,42,295,300,442,436,433,325,207,460,88,464,222,237,369,380
2124,2573,2262,887,1917,480,33,300,1842,274,733,42,325,794,267,2413,369,1246,2497,1248,295,23,1679,1594,1885,1847,2172,2415,207,129,433,2498,2524,409,1348,2054,2055,1646,619,1927,26,620,460,706,1814,20,397,1448,436,1080,2383,2060,1564,464,1082,1206,1208,1733,2062,599,1414,2022,691,222,442,1696,1373,2308,670,380,2517,88,1760,237
-0.5710083209352036,-1.315983932120922,-0.6949533822984102,0.20773293514525631,-0.4223492971351874,0.6062808758329494,3.082238226873909,0.9369680850132093,-0.36473682773465654,1.0092219778652174,0.3240467416918007,2.849109236264797,0.8626989686693847,0.27807073501123514,1.044619903415622,-0.8898717216903321,0.7863246738934979,-0.01377469592003253,-1.0612014774574168,-0.01377469592003253,0.9552170880450557,3.300030759770216,-0.25252550560044684,-0.19787205833249796,-0.3934145562501481,-0.36473682773465654,-0.6015642502581877,-0.8898717216903321,1.2797111548412214,1.7850921167036022,0.6676054254045067,-1.0612014774574168,-1.1321541889327764,0.7077496739843829,-0.06526800225829026,-0.5107324113409443,-0.5107324113409443,-0.22508051495738804,0.4359099189969065,-0.4223492971351874,3.2819030749164693,0.4359099189969065,0.6268724257185203,0.3467667149096307,-0.33631253477906203,3.3590589468435246,0.7276051859633127,-0.1176342396375531,0.6676054254045067,0.08668311743058034,-0.8236504561955251,-0.5107324113409443,-0.17089694126863775,0.6268724257185203,0.08668311743058034,0.011651732815977752,0.011651732815977752,-0.2802102847132027,-0.5107324113409443,0.45777194879673416,-0.09134055376869563,-0.4810044712723359,0.36931090448637094,1.1982044600111101,0.6676054254045067,-0.25252550560044684,-0.06526800225829026,-0.7266710972825526,0.39168144268614885,0.7668911001385372,-1.0964994453628252,2.188669927046933,-0.2802102847132027,1.148018452189637
2,702
Sensory perception
9
30
2.434092
0.014929
O43924,Q13432,Q99797,O60313,Q9Y6M9,P50897,O60443,Q15555,Q14108
Processes and pathways
GO Biological process
msigdb_gobp
36,5,108,239,178,82,55,186,30
36,239,55,1286,2547,1482,2346,919,680,2172,1038,1725,82,2242,1563,2453,2539,5,30,186,2024,468,2230,2615,108,2441,1278,254,650,178
2.9767096391211663,1.1310694730368478,2.5279649567157563,-0.03941367046144973,-1.2045569767363151,-0.14415202790824028,-0.7910150544529415,0.18391141717841533,0.36931090448637094,-0.6015642502581877,0.1112864967658255,-0.2802102847132027,2.2632150164335987,-0.6635325569459647,-0.17089694126863775,-0.957392920200188,-1.1681714201941449,3.8520371556872264,3.1093432588488037,1.3895536705247618,-0.4810044712723359,0.6268724257185203,-0.6324042683431318,-1.5096459874254489,1.9960644529824567,-0.9234673291200788,-0.01377469592003253,1.0795454359625347,0.4138804266239855,1.435179083173316
2,702
Alzheimers disease and mirna effects
24
75
2.432761
0.014984
P28072,P12236,P49768,P49721,P21796,P05141,P45880,P31749,O95197,P07384,P20618,P04350,Q99436,P60900,P28074,P07437,P28070,P48729,Q9NQC3,P68371,Q92542,Q9Y277,P16615,Q9BVA1
Processes and pathways
WikiPathways
msigdb_wp
129,267,397,20,23,274,26,409,33,42,295,300,442,436,433,325,207,460,88,464,222,237,369,380
2124,2573,2262,887,1917,480,33,300,1842,274,733,42,325,794,267,2413,369,1246,2497,1248,295,23,1679,1594,1885,1847,2172,2415,207,129,433,2498,2524,409,1348,2054,2055,1646,619,1927,26,620,460,706,1814,20,397,1448,436,1080,2383,2060,1564,464,1082,1206,1208,1733,2062,599,1414,2022,691,222,985,442,1696,1373,2308,670,380,2517,88,1760,237
-0.5710083209352036,-1.315983932120922,-0.6949533822984102,0.20773293514525631,-0.4223492971351874,0.6062808758329494,3.082238226873909,0.9369680850132093,-0.36473682773465654,1.0092219778652174,0.3240467416918007,2.849109236264797,0.8626989686693847,0.27807073501123514,1.044619903415622,-0.8898717216903321,0.7863246738934979,-0.01377469592003253,-1.0612014774574168,-0.01377469592003253,0.9552170880450557,3.300030759770216,-0.25252550560044684,-0.19787205833249796,-0.3934145562501481,-0.36473682773465654,-0.6015642502581877,-0.8898717216903321,1.2797111548412214,1.7850921167036022,0.6676054254045067,-1.0612014774574168,-1.1321541889327764,0.7077496739843829,-0.06526800225829026,-0.5107324113409443,-0.5107324113409443,-0.22508051495738804,0.4359099189969065,-0.4223492971351874,3.2819030749164693,0.4359099189969065,0.6268724257185203,0.3467667149096307,-0.33631253477906203,3.3590589468435246,0.7276051859633127,-0.1176342396375531,0.6676054254045067,0.08668311743058034,-0.8236504561955251,-0.5107324113409443,-0.17089694126863775,0.6268724257185203,0.08668311743058034,0.011651732815977752,0.011651732815977752,-0.2802102847132027,-0.5107324113409443,0.45777194879673416,-0.09134055376869563,-0.4810044712723359,0.36931090448637094,1.1982044600111101,0.15989814001547026,0.6676054254045067,-0.25252550560044684,-0.06526800225829026,-0.7266710972825526,0.39168144268614885,0.7668911001385372,-1.0964994453628252,2.188669927046933,-0.2802102847132027,1.148018452189637
2,702
Polyneuropathy
7
15
2.417223
0.015639
O95831,O95721,Q9NZJ7,P07602,O60313,Q8N2K0,Q9HC21
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
290,384,365,11,239,188,323
239,384,290,1114,11,1246,502,2468,710,1312,774,188,323,365,1277
1.1310694730368478,0.74731846202068,0.9733415184995973,0.06187795047934465,3.503168251453378,-0.01377469592003253,0.5855369618145146,-0.9916536280362304,0.3467667149096307,-0.03941367046144973,0.3011488166696212,1.3895536705247618,0.881460002398148,0.8056207329272186,-0.01377469592003253
2,702
Gpcr ligand binding
6
9
2.416877
0.015654
P42892,Q9NZJ7,P07602,Q9UBI6,P04083,Q9BYT8
Processes and pathways
Reactome Pathways
msigdb_reactome
95,365,11,403,395,92
395,11,95,1006,92,1183,365,403,527
0.7276051859633127,3.503168251453378,2.1337776504182426,0.13569066148578596,2.1559035701841203,0.036868377335003144,0.8056207329272186,0.7276051859633127,0.5646389006836805
2,702
Metalloprotease
8
26
2.397617
0.016502
P42892,P52888,Q9NZ08,Q99797,O75844,Q9UIQ6,P55786,Q9BYT8
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
95,73,137,108,57,58,157,92
2262,561,2600,57,562,1153,2411,2644,2413,95,73,157,182,1089,1139,2475,1268,108,92,1949,1992,2118,909,137,58,820
-0.6949533822984102,0.5010015722710037,-1.4309487853394973,2.5094973738711897,0.5010015722710037,0.036868377335003144,-0.8898717216903321,-1.9299894948150549,-0.8898717216903321,2.1337776504182426,2.3949755597742,1.5955163931080725,1.404856290131458,0.08668311743058034,0.06187795047934465,-0.9916536280362304,-0.01377469592003253,1.9960644529824567,2.1559035701841203,-0.4223492971351874,-0.4515446964616516,-0.540732380985242,0.20773293514525631,1.7191369886638892,2.500199007739095,0.27807073501123514
2,702
Copi mediated anterograde transport
19
47
2.390087
0.016844
Q13561,P24390,Q15363,O75935,P04350,Q13190,Q9Y3B3,O95249,Q9BVK6,P68371,Q13885,P61923,Q14789,Q14203,Q9UJW0,Q9BVA1,P49755,O15020,Q9Y678
Processes and pathways
Reactome Pathways
msigdb_reactome
387,7,37,418,300,452,68,200,205,464,599,623,628,486,510,380,378,376,393
1916,376,1335,914,1338,418,200,300,920,7,1442,1852,2271,1161,1445,378,1601,1602,1727,1974,1165,623,739,464,710,1567,452,2420,387,626,599,486,798,628,37,2030,905,908,670,380,205,2602,1426,510,68,393,1387
-0.4223492971351874,0.7668911001385372,-0.06526800225829026,0.18391141717841533,-0.06526800225829026,0.687750303214672,1.3115908775571128,0.9369680850132093,0.18391141717841533,3.630300382746048,-0.1176342396375531,-0.36473682773465654,-0.6949533822984102,0.036868377335003144,-0.1176342396375531,0.7668911001385372,-0.19787205833249796,-0.19787205833249796,-0.2802102847132027,-0.4515446964616516,0.036868377335003144,0.4359099189969065,0.3240467416918007,0.6268724257185203,0.3467667149096307,-0.17089694126863775,0.6473133664185765,-0.8898717216903321,0.74731846202068,0.4359099189969065,0.45777194879673416,0.6062808758329494,0.27807073501123514,0.4359099189969065,2.9694470635904917,-0.4810044712723359,0.20773293514525631,0.20773293514525631,0.39168144268614885,0.7668911001385372,1.2957016226393265,-1.4309487853394973,-0.09134055376869563,0.5855369618145146,2.424219700870432,0.74731846202068,-0.06526800225829026
2,702
Ectopic calcification
17
43
2.370906
0.017745
P08236,Q9Y3Z3,P40855,O43175,P38571,O75381,Q14739,O00116,P23786,O60313,P10644,Q9UBM7,O00584,P04062,O75844,P38435,P00403
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
261,455,226,196,449,345,298,382,169,239,111,445,213,125,57,156,407
382,447,213,789,196,239,1339,2396,345,700,57,2398,407,1036,125,824,261,111,1882,1246,1120,921,169,2054,156,449,226,2241,762,1853,2058,1975,2580,298,1607,799,2111,950,783,2081,445,455,2494
0.74731846202068,0.6473133664185765,1.247422490494699,0.27807073501123514,1.3273799247937976,1.1310694730368478,-0.06526800225829026,-0.8566010715319217,0.8247808034059452,0.3467667149096307,2.5094973738711897,-0.8566010715319217,0.7077496739843829,0.1112864967658255,1.8365297753474792,0.254810254426627,1.0621410964140288,1.9360399599594456,-0.3934145562501481,-0.01377469592003253,0.06187795047934465,0.18391141717841533,1.509380323825773,-0.5107324113409443,1.5955163931080725,0.6473133664185765,1.1815848149569044,-0.6635325569459647,0.3011488166696212,-0.36473682773465654,-0.5107324113409443,-0.4515446964616516,-1.315983932120922,0.9552170880450557,-0.19787205833249796,0.27807073501123514,-0.540732380985242,0.18391141717841533,0.3011488166696212,-0.5107324113409443,0.6676054254045067,0.6473133664185765,-1.0262546953488343
2,702
Lytic vacuole organization
7
18
2.360307
0.01826
P10253,O14773,P54802,P50897,Q14108,P04062,P11117
Processes and pathways
GO Biological process
msigdb_gobp
317,199,141,82,30,125,126
512,199,406,125,919,317,126,619,82,1078,141,1125,2220,30,773,877,2408,1385
0.5646389006836805,1.3115908775571128,0.7077496739843829,1.8365297753474792,0.18391141717841533,0.881460002398148,1.8237782990494262,0.4359099189969065,2.2632150164335987,0.08668311743058034,1.678647365092368,0.06187795047934465,-0.6324042683431318,3.1093432588488037,0.3011488166696212,0.2313650943574053,-0.8566010715319217,-0.06526800225829026
2,702
Nucleotide transport
10
14
2.353862
0.018579
P12236,O15439,Q8TB61,Q08722,P05141,Q6NUK1,O43808,Q9H2D1,O00400,Q9HC21
Processes and pathways
GO Biological process
msigdb_gobp
267,479,181,411,274,414,283,60,155,323
155,479,283,274,794,267,856,411,414,181,2614,557,60,323
1.5955163931080725,0.6062808758329494,0.9913427102790784,1.0092219778652174,0.27807073501123514,1.044619903415622,0.2313650943574053,0.7077496739843829,0.7077496739843829,1.4200644560622815,-1.5096459874254489,0.5223730615720535,2.4814715373825837,0.881460002398148
2,702
Secondary alcohol metabolic process
14
36
2.350862
0.01873
Q9BQE5,P48449,Q15800,Q8WTV0,Q6P1A2,Q14739,O15118,P16435,P61916,Q15392,Q16850,O75477,Q14534,P04062
Processes and pathways
GO Biological process
msigdb_gobp
34,130,67,69,227,298,74,361,240,49,50,313,412,125
74,1588,313,2199,595,2094,2435,125,1677,963,361,2587,579,2102,130,2325,564,2648,1928,240,1730,1819,2139,412,298,1982,49,799,67,50,227,69,2309,34,445,1276
2.3553210205573603,-0.19787205833249796,0.9000909263071639,-0.6324042683431318,0.45777194879673416,-0.540732380985242,-0.9234673291200788,1.8365297753474792,-0.25252550560044684,0.15989814001547026,0.8056207329272186,-1.353903802647287,0.47946851200506696,-0.540732380985242,1.7850921167036022,-0.7586901436735312,0.5010015722710037,-1.9746786799606038,-0.4223492971351874,1.1310694730368478,-0.2802102847132027,-0.33631253477906203,-0.5710083209352036,0.7077496739843829,0.9552170880450557,-0.4515446964616516,2.71205420662372,0.27807073501123514,2.433875016635886,2.71205420662372,1.1815848149569044,2.414518252119156,-0.7266710972825526,3.0547069293922724,0.6676054254045067,-0.01377469592003253
2,702
Golgi organization
21
48
2.345486
0.019002
P40616,P63104,O15260,Q8NHH9,P42858,Q15363,P61019,O14976,Q7Z7H5,Q13190,Q9Y3B3,Q9H8Y8,P06493,O14578,Q9BVK6,P48729,Q9BTU6,Q12907,Q14789,Q9P2W9,P49755
Processes and pathways
GO Biological process
msigdb_gobp
386,519,140,663,532,37,686,560,191,452,68,588,578,577,205,460,217,221,628,116,378
577,912,560,1632,140,1586,1338,1766,1340,578,2172,2498,1646,386,532,460,1648,378,1163,1500,686,739,519,1082,221,452,628,37,1053,2251,1463,191,1523,663,905,805,1375,217,205,1579,588,116,951,725,2611,1331,68,958
0.47946851200506696,0.18391141717841533,0.5010015722710037,-0.22508051495738804,1.692221906453172,-0.19787205833249796,-0.06526800225829026,-0.308138168176809,-0.06526800225829026,0.47946851200506696,-0.6015642502581877,-1.0612014774574168,-0.22508051495738804,0.74731846202068,0.5435848808587928,0.6268724257185203,-0.22508051495738804,0.7668911001385372,0.036868377335003144,-0.14415202790824028,0.36931090448637094,0.3240467416918007,0.5646389006836805,0.08668311743058034,1.1982044600111101,0.6473133664185765,0.4359099189969065,2.9694470635904917,0.1112864967658255,-0.6635325569459647,-0.1176342396375531,1.3741556701287698,-0.14415202790824028,0.39168144268614885,0.20773293514525631,0.27807073501123514,-0.06526800225829026,1.247422490494699,1.2957016226393265,-0.17089694126863775,0.47946851200506696,1.8992357988485726,0.18391141717841533,0.3467667149096307,-1.470087388879226,-0.03941367046144973,2.424219700870432,0.18391141717841533
2,702
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
8
14
2.339139
0.019328
Q07065,O43852,Q13217,P07942,Q9BTY2,P14625,Q02818,Q15293
Processes and pathways
Reactome Pathways
msigdb_reactome
328,265,624,334,281,616,62,388
265,892,334,656,616,1923,62,328,624,1570,388,1260,1054,281
1.044619903415622,0.20773293514525631,0.8438063884694104,0.39168144268614885,0.4359099189969065,-0.4223492971351874,2.4625675937937155,0.8626989686693847,0.4359099189969065,-0.17089694126863775,0.74731846202068,-0.01377469592003253,0.1112864967658255,1.0092219778652174
2,702
metalloprotease
8
25
2.336064
0.019488
P42892,P52888,Q9NZ08,Q99797,O75844,Q9UIQ6,P55786,Q9BYT8
Functions
Panther Protein class
panther_protein_class
95,73,137,108,57,58,157,92
561,2600,57,1153,333,2644,2413,1487,2467,2468,95,73,157,1129,182,1089,2475,1268,108,92,1992,909,137,58,820
0.5010015722710037,-1.4309487853394973,2.5094973738711897,0.036868377335003144,0.8438063884694104,-1.9299894948150549,-0.8898717216903321,-0.14415202790824028,-0.9916536280362304,-0.9916536280362304,2.1337776504182426,2.3949755597742,1.5955163931080725,0.06187795047934465,1.404856290131458,0.08668311743058034,-0.9916536280362304,-0.01377469592003253,1.9960644529824567,2.1559035701841203,-0.4515446964616516,0.20773293514525631,1.7191369886638892,2.500199007739095,0.27807073501123514
2,702