term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5
values | subtype stringclasses 24
values | subtype_key stringclasses 24
values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metal ion transmembrane transporter activity | 14 | 24 | 2.630373 | 0.008529 | Q96QD8,Q8N4V1,Q9BXP2,P61619,Q9H2H9,Q9H0U3,Q9Y6M7,P98194,P05023,P16615,Q9UM00,O95202,Q9HD20,P07355 | Functions | GO Molecular function | msigdb_gomf | 389,70,359,169,138,238,143,178,243,252,318,405,58,313 | 405,243,1118,313,2212,1044,252,1024,699,2574,169,178,70,598,1426,468,389,359,238,138,58,318,681,143 | 0.8383751777967641,1.332880448717388,0.000966854535827841,1.1001502232099265,-0.707024253971549,0.05828124665914992,1.3044639973832475,0.07722049678650203,0.36959730040846983,-1.234355168597917,1.6469125414193932,1.5805599528095038,2.3723562686361177,0.5087582951969946,-0.1756174312141384,0.7258267538427401,0.885732352... | 2,701 |
Secondary active transmembrane transporter activity | 16 | 22 | 2.625581 | 0.00865 | Q96ES6,P41440,Q96QD8,P12236,Q9BXP2,Q9H2H9,O00400,P04920,Q9Y6M7,Q00325,Q9UBX3,Q8NE86,P51790,O95202,P53985,Q02978 | Functions | GO Molecular function | msigdb_gomf | 128,321,389,415,359,138,170,462,143,551,47,598,280,405,254,183 | 170,405,462,605,1044,750,415,321,280,813,254,551,183,839,598,128,389,359,138,47,681,143 | 1.6337233768883894,0.8383751777967641,0.7258267538427401,0.49160405626708076,0.05828124665914992,0.31624613864460677,0.8224740869191085,1.085181098032962,1.203511402271728,0.2622351395530162,1.3044639973832475,0.5767080236830171,1.540253330753097,0.24408206050486364,0.5087582951969946,1.9025621688075542,0.8857323527866... | 2,701 |
Inorganic molecular entity transmembrane transporter activity | 40 | 75 | 2.608274 | 0.0091 | P00403,Q96ES6,Q96QD8,Q9Y487,Q9H2H9,Q9Y6M7,P51790,Q7KZN9,O95202,P56385,P45880,Q9Y277,P61619,P10606,O00400,Q9UBX3,P98194,Q9UM00,Q9Y5K8,Q9HD20,Q99797,Q02978,O75964,P21796,P07355,Q8N4V1,P04920,P31930,Q96ER9,Q13423,P13073,Q93050,P33527,Q9C0H2,Q9BXP2,Q9H0U3,P05023,Q9UDW1,O15439,P16615 | Functions | GO Molecular function | msigdb_gomf | 251,128,389,134,138,143,280,152,405,407,28,166,169,298,170,47,178,318,452,58,317,183,57,62,313,70,462,81,468,340,343,91,348,94,359,238,243,118,248,252 | 2227,170,248,536,2015,57,405,251,462,243,1118,605,1568,313,2212,1044,749,298,750,343,252,1024,1076,1343,1602,62,699,622,2337,81,348,1777,1882,2191,28,2573,2574,280,813,2306,407,471,169,178,551,183,340,518,1961,152,70,598,1836,1426,91,468,128,389,566,317,359,94,238,138,58,47,118,1433,318,166,681,134,452,2099,143 | -0.7296754780456444,1.6337233768883894,1.3186955452496854,0.593531179510868,-0.5516452556198194,2.5038189105500694,0.8383751777967641,1.3044639973832475,0.7258267538427401,1.332880448717388,0.000966854535827841,0.49160405626708076,-0.27688196692354466,1.1001502232099265,-0.707024253971549,0.05828124665914992,0.31624613... | 2,701 |
Inner mitochondrial membrane organization | 16 | 21 | 2.602183 | 0.009263 | P17152,O60313,Q16891,Q9P0J0,Q13505,Q6UXV4,Q8WWC4,Q5XKP0,Q9Y5J7,Q9Y5J9,Q9Y512,O75431,Q9Y4W6,Q9BUR5,O95202,Q9H3K2 | Processes and pathways | GO Biological process | msigdb_gobp | 320,189,388,133,296,200,140,273,276,209,212,309,469,186,405,223 | 189,309,684,405,320,2594,296,388,596,273,200,140,186,223,475,1335,133,469,212,276,209 | 1.5131717487404053,1.115067853889435,0.38723710682081225,0.8383751777967641,1.085181098032962,-1.3373751235719122,1.1595152238833708,0.8857323527866384,0.5087582951969946,1.2470652835370355,1.4859193366122214,1.8147994633249862,1.540253330753097,1.4031156606893533,0.7095080229146791,-0.11596206747168612,1.8901336133115... | 2,701 |
Endoplasmic reticulum organization | 20 | 38 | 2.59768 | 0.009386 | Q8NHH9,Q00765,O95197,P50542,Q12981,O43681,P61619,Q15629,Q9P2W9,O00429,Q8N4V1,Q6P1A2,P49257,Q5J8M3,Q15363,P57088,Q96A33,Q9NXE4,Q9NQC3,Q9NP72 | Processes and pathways | GO Biological process | msigdb_gobp | 512,395,10,516,543,536,169,41,181,434,70,586,583,465,349,227,236,504,122,641 | 1277,434,1070,1374,1767,536,1489,1770,10,1117,1210,583,516,227,169,395,801,543,2145,349,41,465,1355,586,2691,70,660,1268,512,236,927,641,692,122,504,1197,1168,181 | -0.09625596283480581,0.7744188751377666,0.03925969392486323,-0.1556420051329787,-0.40156531384122846,0.593531179510868,-0.23609532189713084,-0.40156531384122846,3.6262130177039786,0.000966854535827841,-0.05710757719101301,0.5258452995193653,0.6269838228448695,1.3891595529580087,1.6469125414193932,0.8700039001223019,0.2... | 2,701 |
SLC25 family of mitochondrial transporters | 9 | 18 | 2.582479 | 0.009809 | O43772,Q70HW3,Q9UBX3,Q9NZJ7,Q9BQT8,O43808,Q9H2D1,Q02978,Q9Y6C9 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 103,11,47,146,50,147,22,183,92 | 103,147,889,605,750,415,551,183,344,11,50,22,220,146,47,666,933,92 | 2.060949321084514,1.7638347606018192,0.18916598311737365,0.49160405626708076,0.31624613864460677,0.8224740869191085,0.5767080236830171,1.540253330753097,1.0095506891404633,3.617915206963102,2.578682101820039,3.1065707089213883,1.417026875112562,1.7766325496335293,2.6626661752675664,0.42230424858015453,0.170706245310589... | 2,701 |
Mitochondrial carrier domain superfamily [IPR023395] | 9 | 18 | 2.582479 | 0.009809 | O43772,Q70HW3,Q9UBX3,Q9NZJ7,Q9BQT8,O43808,Q9H2D1,Q02978,Q9Y6C9 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 103,11,47,146,50,147,22,183,92 | 103,147,889,605,750,415,551,183,344,11,50,22,220,146,47,666,933,92 | 2.060949321084514,1.7638347606018192,0.18916598311737365,0.49160405626708076,0.31624613864460677,0.8224740869191085,0.5767080236830171,1.540253330753097,1.0095506891404633,3.617915206963102,2.578682101820039,3.1065707089213883,1.417026875112562,1.7766325496335293,2.6626661752675664,0.42230424858015453,0.170706245310589... | 2,701 |
Mitochondrial substrate/solute carrier [IPR018108] | 9 | 18 | 2.582479 | 0.009809 | O43772,Q70HW3,Q9UBX3,Q9NZJ7,Q9BQT8,O43808,Q9H2D1,Q02978,Q9Y6C9 | Sequence | InterPro Repeat | interpro_repeat | 103,11,47,146,50,147,22,183,92 | 103,147,889,605,750,415,551,183,344,11,50,22,220,146,47,666,933,92 | 2.060949321084514,1.7638347606018192,0.18916598311737365,0.49160405626708076,0.31624613864460677,0.8224740869191085,0.5767080236830171,1.540253330753097,1.0095506891404633,3.617915206963102,2.578682101820039,3.1065707089213883,1.417026875112562,1.7766325496335293,2.6626661752675664,0.42230424858015453,0.170706245310589... | 2,701 |
er | 50 | 77 | 2.575087 | 0.010021 | Q8NHH9,P04843,O15173,Q15392,Q07065,Q8TCJ2,Q9Y487,O14735,Q00765,Q8N766,O95470,O75340,Q06136,Q969V3,Q9NR31,Q16850,P49755,Q12981,Q9Y5M8,P61019,O75915,P51153,P51151,Q86Y07,O00400,O95674,Q9NTJ5,P48651,Q14739,Q9P2W9,O00264,Q969Q5,Q9UM00,Q8NF37,P27824,Q8N4V1,O00767,Q5J8M3,P48449,O96005,Q15738,Q13190,Q15363,P46977,Q96A33,Q969M... | Localization | OpenCell Localization | opencell_localization | 512,635,127,131,263,648,134,642,395,660,144,272,18,274,275,278,277,543,158,541,537,675,164,556,170,172,694,175,53,181,308,311,318,184,570,70,335,465,83,85,594,215,349,229,236,376,619,122,641,253 | 308,170,335,642,127,1972,2071,1767,272,619,537,1117,144,172,85,1696,635,1023,2281,1150,1441,570,1078,229,83,175,277,164,675,253,2341,1638,2142,541,943,1125,395,18,263,543,215,53,2145,349,131,594,2086,278,465,1191,2088,556,70,660,184,512,648,2437,2090,376,311,274,236,927,1194,641,692,122,275,694,1197,1168,181,318,792,13... | 1.115067853889435,1.6337233768883894,1.0399612405003023,0.439732694154855,1.9025621688075542,-0.5298892096352652,-0.5954826549590951,-0.40156531384122846,1.2470652835370355,0.47438206198749655,0.593531179510868,0.000966854535827841,1.7893924505266094,1.6072235088664195,2.213707758412066,-0.3596097669606752,0.4570917855... | 2,701 |
Ion channel transport | 11 | 27 | 2.557539 | 0.010542 | Q93050,Q9Y487,P98194,P05023,Q15904,P16615,P51790,Q9Y5K8,Q9HD20,P61421,Q9C0H2 | Processes and pathways | Reactome Pathways | msigdb_reactome | 91,134,178,243,436,252,280,452,58,471,94 | 243,1118,252,1024,1343,1602,699,1283,1882,2191,280,813,624,471,178,1262,1506,436,518,1296,91,1757,94,58,1433,134,452 | 1.332880448717388,0.000966854535827841,1.3044639973832475,0.07722049678650203,-0.1357571511500396,-0.2974182770678407,0.36959730040846983,-0.09625596283480581,-0.4652592172226013,-0.6844888552895658,1.203511402271728,0.2622351395530162,0.47438206198749655,0.7095080229146791,1.5805599528095038,-0.07663805632366444,-0.23... | 2,701 |
Sphingolipid metabolism | 6 | 10 | 2.553387 | 0.010668 | P07602,P17900,Q9NZ01,O95470,Q06136,Q13510 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 31,163,6,144,18,119 | 1972,2071,144,177,31,163,18,119,1509,6 | -0.5298892096352652,-0.5954826549590951,1.7893924505266094,1.5805599528095038,2.8458055936098234,1.6862398498357258,3.244826799017829,1.951920624080694,-0.23609532189713084,3.953135916812116 | 2,701 |
Copii coated er to golgi transport vesicle | 16 | 29 | 2.539477 | 0.011102 | Q9Y3A6,Q9BVK6,Q9Y3B3,P49257,O75340,Q5VYK3,O95487,Q9NR31,Q9Y282,P49755,P10321,Q13190,Q969M3,Q7Z7H5,Q15363,O95070 | Localization | GO Cellular component | msigdb_gocc | 430,174,302,583,272,530,304,275,54,277,563,215,376,219,349,159 | 1374,1974,272,619,1770,159,1567,304,2105,563,583,277,1992,1009,801,215,349,2084,1161,530,219,376,174,275,1967,54,430,302,711 | -0.1556420051329787,-0.5298892096352652,1.2470652835370355,0.47438206198749655,-0.40156531384122846,1.6992696820323683,-0.27688196692354466,1.1299343362894672,-0.6175661397525806,0.559819657694308,0.5258452995193653,1.2180780751359057,-0.5298892096352652,0.0960781397108018,0.28031310881637544,1.4308934785310223,0.99426... | 2,701 |
Cholesterol binding | 6 | 12 | 2.530948 | 0.011375 | O15118,P61916,Q14108,Q9H4L5,P45880,P21796 | Functions | GO Molecular function | msigdb_gomf | 130,72,21,153,28,62 | 130,794,1817,2212,62,1440,195,28,72,21,1194,153 | 1.8901336133115505,0.28031310881637544,-0.4226942464977029,-0.707024253971549,2.460444745964291,-0.19568424190462033,1.4995670283946096,2.905147117866422,2.36121680514361,3.1159288248830843,-0.03766376468274858,1.7381246312443195 | 2,701 |
Active transmembrane transporter activity | 39 | 72 | 2.530059 | 0.011404 | P00403,Q96ES6,O43676,Q9P0J0,Q96QD8,Q9H2H9,Q16718,Q9Y6M7,P51790,Q7KZN9,O95202,Q9Y6M9,O96000,P12236,O95169,P10606,O00400,Q9UBX3,P98194,P08183,Q02978,Q9Y5K8,Q9HD20,P41440,O95168,P04920,P31930,P13073,P61421,P33527,P28288,O75306,Q9BXP2,P05023,Q9UDW1,O75027,O15439,P53985,P16615 | Functions | GO Molecular function | msigdb_gomf | 251,128,4,133,389,138,399,143,280,152,405,30,290,415,295,298,170,47,178,180,183,452,58,321,325,462,81,343,471,348,470,478,359,243,118,371,248,254,252 | 2556,170,1115,248,4,1973,371,2516,478,1528,2230,325,295,2442,405,2017,290,251,462,243,1118,605,1568,180,1044,749,298,750,415,343,252,2561,1024,1076,1343,1602,699,470,2046,81,348,1882,2191,321,2608,280,813,1256,254,471,178,551,183,498,839,399,609,152,598,128,389,359,138,58,133,47,118,1433,681,452,143,30 | -1.2089703136081216,1.6337233768883894,0.000966854535827841,1.3186955452496854,4.14073910845815,-0.5298892096352652,0.9325789136855012,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,0.8383751777967641,-0.5516452556198194,1.174230... | 2,701 |
Intermediate filament cytoskeleton | 10 | 31 | 2.509318 | 0.012096 | P58107,Q15149,P15924,Q16352,P14923,O75832,Q3SXM5,P02545,P48729,P08670 | Localization | GO Cellular component | msigdb_gocc | 101,198,14,78,16,303,19,214,380,286 | 1811,303,214,1494,1379,286,16,14,2215,941,380,1475,2496,101,2645,1538,2307,198,78,2086,19,840,649,628,1368,857,821,1234,451,930,1849 | -0.4226942464977029,1.1299343362894672,1.4308934785310223,-0.23609532189713084,-0.1556420051329787,1.1888955874119858,3.2538860606266975,3.3434324737059566,-0.707024253971549,0.15216824938562942,0.9170194617840494,-0.21584326062426626,-1.0841853199459772,2.072894727430521,-1.6616232828965283,-0.25644127155135765,-0.798... | 2,701 |
Sterol metabolic process | 14 | 32 | 2.509248 | 0.012099 | O15118,Q15392,Q9UBM7,Q8WTV0,P16435,Q14534,P37268,P61916,Q9BQE5,P04062,P48449,Q14739,Q16850,Q15800 | Processes and pathways | GO Biological process | msigdb_gobp | 130,131,36,322,441,327,69,72,12,177,83,53,278,409 | 130,794,620,1817,1696,177,1819,940,441,2216,69,2509,2385,83,455,1991,72,2266,2418,2471,327,53,2220,131,594,409,278,586,322,12,36,2475 | 1.8901336133115505,0.28031310881637544,0.47438206198749655,-0.4226942464977029,-0.3596097669606752,1.5805599528095038,-0.4226942464977029,0.15216824938562942,0.7582817372111945,-0.707024253971549,2.3945487262934133,-1.1088623151263601,-0.8915779896099613,2.2367341600459416,0.742084510223003,-0.5298892096352652,2.361216... | 2,701 |
Lipid transporter activity | 11 | 19 | 2.495945 | 0.012562 | O15118,P17900,P30536,P61916,Q01469,P08183,P33527,O15439,Q9H4L5,P28288,P11166 | Functions | GO Molecular function | msigdb_gomf | 130,163,195,72,51,180,348,248,153,470,222 | 130,248,180,222,163,797,470,195,348,1050,72,51,518,1191,1296,610,1688,1194,153 | 1.8901336133115505,1.3186955452496854,1.5537307142177417,1.4031156606893533,1.6862398498357258,0.28031310881637544,0.7095080229146791,1.4995670283946096,0.9942651268493035,0.05828124665914992,2.36121680514361,2.568067202131094,0.6269838228448695,-0.03766376468274858,-0.09625596283480581,0.49160405626708076,-0.338781277... | 2,701 |
Mitochondrial transmembrane transport | 27 | 46 | 2.468859 | 0.013554 | Q99595,Q9BVV7,Q8WWC4,Q9H2D1,O95202,P56385,P12236,Q3ZCQ8,O95831,Q00325,Q96NB2,Q9BQT8,O95563,O75964,P23786,P21796,O96008,O14925,Q8NE86,Q96ER9,Q9Y4W6,O75027,P05141,O43772,Q9H9B4,Q15388,Q6P4A7 | Processes and pathways | GO Biological process | msigdb_gobp | 3,390,140,22,405,407,415,417,297,551,176,50,435,57,182,62,326,196,598,468,469,371,605,103,630,498,120 | 196,712,103,371,1493,889,2015,57,684,405,435,297,326,605,1568,2654,750,415,62,182,622,2337,1777,2573,2306,407,551,498,417,120,598,2367,140,468,176,3,906,50,390,22,630,2178,666,766,469,933 | 1.4859193366122214,0.351885919191322,2.060949321084514,0.9325789136855012,-0.23609532189713084,0.18916598311737365,-0.5516452556198194,2.5038189105500694,0.38723710682081225,0.8383751777967641,0.7744188751377666,1.1447500131709183,1.0701601286370668,0.49160405626708076,-0.27688196692354466,-1.746524104659968,0.31624613... | 2,701 |
transporter | 16 | 56 | 2.46844 | 0.01357 | P41440,Q99595,Q8NFH4,O43772,P61619,Q99805,Q9HD45,Q8TEX9,Q9H2V7,Q9NR77,Q9H2D1,Q567V2,Q15070,O15397,P52292,P53985 | Functions | Panther Protein class | panther_protein_class | 321,3,249,103,169,202,42,269,246,113,22,86,56,240,26,254 | 1173,845,1434,1524,1626,240,712,536,103,2355,1001,795,1604,2050,321,1050,1887,26,1389,2112,254,623,834,1009,835,169,487,1508,56,86,1961,1897,647,249,1898,269,467,1087,1869,600,1459,3,202,338,2501,725,22,246,708,42,113,548,1199,766,997,933 | -0.03766376468274858,0.22585325728994807,-0.19568424190462033,-0.25644127155135765,-0.3180510829696362,1.332880448717388,0.351885919191322,0.593531179510868,2.060949321084514,-0.8680821176442824,0.0960781397108018,0.28031310881637544,-0.2974182770678407,-0.5735093847387928,1.085181098032962,0.05828124665914992,-0.46525... | 2,701 |
Primary active transmembrane transporter activity | 25 | 51 | 2.466112 | 0.013659 | P00403,O43676,Q9P0J0,Q16718,Q7KZN9,Q9Y6M9,O96000,O95169,P10606,P98194,P08183,Q9Y5K8,Q9HD20,O95168,P31930,P13073,P61421,P28288,P33527,O75306,P05023,Q9UDW1,O75027,O15439,P16615 | Functions | GO Molecular function | msigdb_gomf | 251,4,133,399,152,30,290,295,298,178,180,452,58,325,81,343,471,470,348,478,243,118,371,248,252 | 2556,1115,248,4,1973,371,2516,478,1528,2230,325,295,2442,2017,290,251,243,1118,1568,180,749,298,343,252,2561,1024,1076,1343,1602,699,470,2046,81,348,1882,2191,2608,813,1256,471,178,498,399,609,152,58,133,118,1433,452,30 | -1.2089703136081216,0.000966854535827841,1.3186955452496854,4.14073910845815,-0.5298892096352652,0.9325789136855012,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,1.1742303044100273,1.3044639973832475,1.332880... | 2,701 |
Sulfur compound transmembrane transporter activity | 7 | 9 | 2.438835 | 0.014735 | Q8TB61,Q70HW3,O00400,Q9UBX3,O15439,Q9HC21,Q02978 | Functions | GO Molecular function | msigdb_gomf | 136,11,170,47,248,220,183 | 170,248,348,183,11,136,220,47,681 | 1.6337233768883894,1.3186955452496854,0.9942651268493035,1.540253330753097,3.617915206963102,1.8526312438376766,1.417026875112562,2.6626661752675664,0.4048059034205665 | 2,701 |
Membrane lipid biosynthetic process | 8 | 17 | 2.437475 | 0.01479 | Q99805,Q96G23,Q9P035,P04062,Q06136,O95470,Q13510,Q8NBX0 | Processes and pathways | GO Biological process | msigdb_gobp | 202,27,208,177,18,144,119,59 | 1972,2071,144,177,797,18,119,1509,596,59,287,27,1300,202,504,208,1168 | -0.5298892096352652,-0.5954826549590951,1.7893924505266094,1.5805599528095038,0.28031310881637544,3.244826799017829,1.951920624080694,-0.23609532189713084,0.5087582951969946,2.48218674176581,1.1888955874119858,2.92474561480173,-0.09625596283480581,1.4859193366122214,0.6601814574178648,1.4722284064322555,-0.018305867866... | 2,701 |
Sterol binding | 6 | 15 | 2.435478 | 0.014872 | O15118,P61916,Q14108,Q9H4L5,P45880,P21796 | Functions | GO Molecular function | msigdb_gomf | 130,72,21,153,28,62 | 130,794,1817,2212,62,797,1440,195,28,72,21,610,1688,1194,153 | 1.8901336133115505,0.28031310881637544,-0.4226942464977029,-0.707024253971549,2.460444745964291,0.28031310881637544,-0.19568424190462033,1.4995670283946096,2.905147117866422,2.36121680514361,3.1159288248830843,0.49160405626708076,-0.33878127776425015,-0.03766376468274858,1.7381246312443195 | 2,701 |
Alcohol binding | 6 | 14 | 2.434278 | 0.014922 | O15118,P61916,Q14108,Q9H4L5,P45880,P21796 | Functions | GO Molecular function | msigdb_gomf | 130,72,21,153,28,62 | 642,130,794,1817,2212,62,1440,1820,195,28,72,21,1194,153 | 0.439732694154855,1.8901336133115505,0.28031310881637544,-0.4226942464977029,-0.707024253971549,2.460444745964291,-0.19568424190462033,-0.4226942464977029,1.4995670283946096,2.905147117866422,2.36121680514361,3.1159288248830843,-0.03766376468274858,1.7381246312443195 | 2,701 |
secondary carrier transporter | 10 | 15 | 2.41934 | 0.015549 | Q96ES6,Q9BXP2,Q8TB61,O00400,Q9Y6M7,Q9UBX3,Q6NT16,Q9BQT8,Q02978,O95202 | Functions | Panther Protein class | panther_protein_class | 128,359,136,170,143,47,49,50,183,405 | 170,889,405,462,183,49,1191,136,128,50,359,47,666,681,143 | 1.6337233768883894,0.18916598311737365,0.8383751777967641,0.7258267538427401,1.540253330753097,2.5892707322696364,-0.03766376468274858,1.8526312438376766,1.9025621688075542,2.578682101820039,0.9635315701724516,2.6626661752675664,0.42230424858015453,0.4048059034205665,1.802114682609706 | 2,701 |
Vitamin transport | 7 | 9 | 2.417434 | 0.01563 | P41440,Q8WTV0,P04062,P38435,Q9H2D1,Q9HC21,P11166 | Processes and pathways | GO Biological process | msigdb_gobp | 321,322,177,114,22,220,222 | 177,222,348,114,321,322,22,220,681 | 1.5805599528095038,1.4031156606893533,0.9942651268493035,2.0128330114691035,1.085181098032962,1.085181098032962,3.1065707089213883,1.417026875112562,0.4048059034205665 | 2,701 |
Exopeptidase activity | 11 | 28 | 2.407125 | 0.016079 | P09960,P10619,O75844,Q9UIQ6,P42785,P55786,Q13867,Q969V3,Q9HB40,Q9H3G5,O14773 | Functions | GO Molecular function | msigdb_gomf | 226,168,43,142,109,17,145,274,256,288,319 | 319,43,1470,808,226,168,2642,2508,1703,1098,109,17,2611,145,880,466,843,274,2091,2326,288,1369,256,1331,1370,1040,360,142 | 1.085181098032962,2.734822878575379,-0.21584326062426626,0.2622351395530162,1.3891595529580087,1.6469125414193932,-1.6336795739285952,-1.1088623151263601,-0.3596097669606752,0.02015513431309902,2.0489706294219476,3.244826799017829,-1.3897974292022441,1.7766325496335293,0.20754810800791113,0.7258267538427401,0.244082060... | 2,701 |
Nonalcoholic fatty liver disease | 15 | 44 | 2.401688 | 0.01632 | P00403,P14406,O96000,O14949,O43676,Q9P0J0,Q16611,O95169,O95168,Q86Y39,P10606,P31930,Q9UDW1,P21912,Q9Y6M9 | Processes and pathways | WikiPathways | msigdb_wp | 251,1,290,65,4,133,37,295,325,104,298,81,118,314,30 | 2556,1115,65,4,1973,2516,478,1528,2230,325,295,2442,2017,290,251,1042,749,1950,298,343,1,1471,2561,1076,314,569,2046,2397,636,81,812,2608,1256,643,1448,1929,2267,37,399,609,104,133,118,30 | -1.2089703136081216,0.000966854535827841,2.4276234185896435,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,1.1742303044100273,1.3044639973832475,0.05828124665914992,0.31624... | 2,701 |
MFS transporter superfamily [IPR036259] | 7 | 9 | 2.399436 | 0.01642 | P41440,Q96ES6,O00400,Q9H2V7,Q6NT16,P53985,P11166 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 321,128,170,246,49,254,222 | 170,222,321,254,1961,49,128,338,246 | 1.6337233768883894,1.4031156606893533,1.085181098032962,1.3044639973832475,-0.5082402040270202,2.5892707322696364,1.9025621688075542,1.0399612405003023,1.332880448717388 | 2,701 |
Lipid localization | 26 | 64 | 2.396271 | 0.016563 | O15118,Q9BQE5,Q9NZJ7,O43808,Q14108,Q9H4L5,O15260,P07602,P17900,O95674,P04062,Q01469,P08183,Q9BUR5,P23786,P07355,Q8WTV0,P30536,Q14534,P61916,P33527,P11166,Q9H6V9,O43772,Q9H2V7,O15439 | Processes and pathways | GO Biological process | msigdb_gobp | 130,12,146,147,21,153,285,31,163,172,177,51,180,186,182,313,322,195,327,72,348,222,96,103,246,248 | 1277,2698,130,285,248,103,147,1377,1567,1437,172,2583,177,890,313,31,829,1633,180,222,716,163,797,1440,182,470,1820,195,636,1248,348,365,1050,72,2266,51,1081,21,327,518,446,586,1191,721,1296,2579,322,610,501,12,927,186,1688,1194,1366,246,153,96,146,1168,2475,766,1909,710 | -0.09625596283480581,-4.819863517888487,1.8901336133115505,1.1888955874119858,1.3186955452496854,2.060949321084514,1.7638347606018192,-0.1556420051329787,-0.27688196692354466,-0.19568424190462033,1.6072235088664195,-1.3113946688909883,1.5805599528095038,0.18916598311737365,1.1001502232099265,2.8458055936098234,0.244082... | 2,701 |
Sensory perception | 10 | 30 | 2.395379 | 0.016603 | O60313,P50897,Q9Y5J9,Q9Y5J7,Q01469,O60443,Q14108,Q9UM54,Q13432,Q9Y6M9 | Processes and pathways | GO Biological process | msigdb_gobp | 189,74,209,276,51,241,21,157,255,30 | 423,189,241,2209,2558,1629,891,829,699,1880,1822,2358,74,2234,2116,51,2481,255,21,584,1356,1755,1659,1934,317,2037,157,276,209,30 | 0.8065146214158287,1.5131717487404053,1.332880448717388,-0.707024253971549,-1.2089703136081216,-0.3180510829696362,0.18916598311737365,0.24408206050486364,0.36959730040846983,-0.4652592172226013,-0.4226942464977029,-0.8680821176442824,2.3163672654572762,-0.7296754780456444,-0.6175661397525806,2.568067202131094,-1.05964... | 2,701 |
Tetrapyrrole binding | 8 | 15 | 2.393505 | 0.016688 | O15173,O43169,P30519,Q6UW02,Q96EY8,O00264,Q16850,Q7KZN9 | Functions | GO Molecular function | msigdb_gomf | 127,0,66,165,79,308,278,152 | 308,127,0,749,672,581,66,278,165,152,900,79,1362,347,1941 | 1.115067853889435,1.9025621688075542,5.210648084460358,0.31624613864460677,0.4048059034205665,0.5258452995193653,2.416626861835804,1.2180780751359057,1.6862398498357258,1.7381246312443195,0.18916598311737365,2.2710437709642273,-0.1357571511500396,1.0095506891404633,-0.4866972109565579 | 2,701 |
Protein transporter activity | 11 | 13 | 2.383936 | 0.017129 | Q9NS69,Q99595,O96008,P61619,O14925,Q9Y5J9,Q8NBU5,Q15388,P49755,Q9HD20,Q07820 | Functions | GO Molecular function | msigdb_gomf | 2,3,326,169,196,209,402,498,277,58,510 | 196,684,326,277,169,510,498,402,3,58,2,515,209 | 1.4859193366122214,0.38723710682081225,1.0701601286370668,1.2180780751359057,1.6469125414193932,0.6436142777409396,0.6601814574178648,0.8542183112675076,4.492615277702867,2.5038189105500694,5.159139452386764,0.6436142777409396,1.4722284064322555 | 2,701 |
Vascular transport | 9 | 15 | 2.383532 | 0.017147 | P41440,Q9H2H9,Q99808,Q01469,P08183,O15439,P53985,P33527,P11166 | Processes and pathways | GO Biological process | msigdb_gobp | 321,138,338,51,180,248,254,348,222 | 248,808,180,222,699,348,321,254,51,839,1191,389,338,138,681 | 1.3186955452496854,0.2622351395530162,1.5537307142177417,1.4031156606893533,0.36959730040846983,0.9942651268493035,1.085181098032962,1.3044639973832475,2.568067202131094,0.24408206050486364,-0.03766376468274858,0.8857323527866384,1.0399612405003023,1.8400575311170198,0.4048059034205665 | 2,701 |
Ion transport | 24 | 53 | 2.373016 | 0.017643 | Q96QD8,Q9Y487,Q9H2H9,Q9Y6M7,P51790,O95202,P56385,P45880,Q9Y277,P98194,Q15904,Q9UM00,Q9Y5K8,O75964,Q9H0H5,P21796,O96008,P04920,Q96ER9,Q93050,Q9C0H2,Q8NEW0,P05023,P16615 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 389,134,138,143,280,405,407,28,166,178,436,318,452,57,450,62,326,462,468,91,94,95,243,252 | 2227,2015,57,405,326,462,243,1118,1568,252,1024,1343,1602,62,699,622,2337,1777,1882,2191,28,2573,280,813,624,2306,407,471,178,2198,436,518,1961,1267,598,95,1836,91,468,389,566,906,94,450,138,1433,318,166,681,134,452,2099,143 | -0.7296754780456444,-0.5516452556198194,2.5038189105500694,0.8383751777967641,1.0701601286370668,0.7258267538427401,1.332880448717388,0.000966854535827841,-0.27688196692354466,1.3044639973832475,0.07722049678650203,-0.1357571511500396,-0.2974182770678407,2.460444745964291,0.36959730040846983,0.47438206198749655,-0.8447... | 2,701 |
Rac2 gtpase cycle | 15 | 32 | 2.369237 | 0.017825 | O15173,Q13505,Q86Y07,P50402,Q86XL3,P49257,Q14185,P51149,Q9Y512,Q14739,Q7L576,P42167,Q9H0H5,Q9Y2U8,Q6IAA8 | Processes and pathways | Reactome Pathways | msigdb_reactome | 127,296,556,197,187,583,719,774,212,53,704,379,450,806,446 | 127,1117,808,1043,980,1923,379,985,583,197,774,1446,1448,2236,989,296,1159,719,53,1057,1291,446,704,187,556,927,450,2095,1065,1201,806,212 | 1.9025621688075542,0.000966854535827841,0.2622351395530162,0.05828124665914992,0.11485486211702632,-0.4866972109565579,0.9170194617840494,0.11485486211702632,0.5258452995193653,1.4859193366122214,0.2983165752789475,-0.19568424190462033,-0.19568424190462033,-0.7296754780456444,0.11485486211702632,1.1595152238833708,-0.0... | 2,701 |
Vitamin transmembrane transporter activity | 6 | 8 | 2.362967 | 0.018129 | P41440,P04062,P38435,Q9H2D1,Q9HC21,P11166 | Functions | GO Molecular function | msigdb_gomf | 321,177,114,22,220,222 | 177,222,348,114,321,22,220,681 | 1.5805599528095038,1.4031156606893533,0.9942651268493035,2.0128330114691035,1.085181098032962,3.1065707089213883,1.417026875112562,0.4048059034205665 | 2,701 |
Electron transport | 15 | 42 | 2.352101 | 0.018668 | O43169,P00403,O96000,O14949,O43676,Q9P0J0,O95169,Q6DKK2,Q86Y39,Q9H1E5,P31930,Q9UDW1,P21912,Q9H3N1,Q9Y6M9 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 0,251,290,65,4,133,295,102,104,111,81,118,314,29,30 | 2556,1115,65,0,1146,4,1973,2516,478,1528,2230,325,295,2442,2017,479,290,251,749,2457,2561,314,2216,569,2046,2397,81,2617,2608,1256,608,399,609,2576,102,104,1136,111,29,133,118,30 | -1.2089703136081216,0.000966854535827841,2.4276234185896435,5.210648084460358,-0.01830586786658518,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,0.6931278673873417,1.17423... | 2,701 |
Skin development | 7 | 36 | 2.344813 | 0.019037 | Q15392,P35222,O75844,P15924,P14923,P04062,Q13510 | Processes and pathways | GO Biological process | msigdb_gobp | 131,73,43,14,16,177,119 | 696,1342,2253,43,177,890,980,16,14,1918,981,621,2383,73,2574,1993,1859,2168,1451,2287,119,1575,1718,198,1014,131,499,594,946,1191,1683,2421,1622,1431,932,2099 | 0.36959730040846983,-0.1357571511500396,-0.7524437006538256,2.734822878575379,1.5805599528095038,0.18916598311737365,0.11485486211702632,3.2538860606266975,3.3434324737059566,-0.4866972109565579,0.11485486211702632,0.47438206198749655,-0.8915779896099613,2.3276237027439657,-1.234355168597917,-0.5298892096352652,-0.4439... | 2,701 |
Cytochrome complex | 7 | 15 | 2.34323 | 0.019118 | P00403,O14949,P14406,P10606,P31930,Q9UDW1,Q7KZN9 | Localization | GO Cellular component | msigdb_gocc | 251,65,1,298,81,118,152 | 1115,65,251,749,1950,298,343,1,1471,1076,569,81,152,118,617 | 0.000966854535827841,2.4276234185896435,1.3044639973832475,0.31624613864460677,-0.5082402040270202,1.1447500131709183,1.0095506891404633,5.210648084460358,-0.21584326062426626,0.03925969392486323,0.5428655840352268,2.248201202031891,1.7381246312443195,1.9763891703113325,0.49160405626708076 | 2,701 |
Nucleotide transport | 10 | 14 | 2.342224 | 0.019169 | O15439,Q08722,P41440,Q8TB61,O00400,Q99808,O43808,Q9H2D1,Q6NUK1,Q9HC21 | Processes and pathways | GO Biological process | msigdb_gobp | 248,354,321,136,170,338,147,22,344,220 | 170,248,147,605,750,415,321,354,344,136,1836,338,22,220 | 1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,0.9789255457318856,1.0095506891404633,1.8526312438376766,-0.4226942464977029,1.0399612405003023,3.1065707089213883,1.417026875112562 | 2,701 |
Exocytic vesicle | 15 | 31 | 2.341394 | 0.019212 | P09497,P51153,O00429,P50897,Q12846,Q9BVK6,Q15907,P11279,Q92542,Q14141,O43760,O15400,P51790,Q9BT78,P61421 | Localization | GO Cellular component | msigdb_gocc | 698,675,434,74,529,174,266,80,599,375,52,561,280,346,471 | 434,1145,561,52,2188,698,80,1024,1671,1496,2574,74,774,675,280,1350,1639,471,529,838,375,1650,1616,1129,266,721,599,1796,346,174,1059 | 0.7744188751377666,-0.01830586786658518,0.559819657694308,2.5574259051028014,-0.6844888552895658,0.36959730040846983,2.248201202031891,0.07722049678650203,-0.33878127776425015,-0.23609532189713084,-1.234355168597917,2.3163672654572762,0.2983165752789475,0.4048059034205665,1.203511402271728,-0.1357571511500396,-0.318051... | 2,701 |
Respiratory chain | 11 | 29 | 2.337427 | 0.019417 | P00403,O14949,O96000,O43676,Q9P0J0,O95169,Q6DKK2,Q86Y39,P31930,Q9UDW1,Q9Y6M9 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 251,65,290,4,133,295,102,104,81,118,30 | 2556,1115,65,4,1973,2516,478,1528,2230,325,295,2442,2017,290,251,749,2561,569,2046,81,2608,1256,399,609,102,104,133,118,30 | -1.2089703136081216,0.000966854535827841,2.4276234185896435,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,1.1742303044100273,1.3044639973832475,0.31624613864460677,-1.2089... | 2,701 |
Nucleotide transmembrane transporter activity | 9 | 12 | 2.336006 | 0.019491 | O15439,P41440,Q8TB61,O00400,Q99808,O43808,Q9H2D1,Q6NUK1,Q9HC21 | Functions | GO Molecular function | msigdb_gomf | 248,321,136,170,338,147,22,344,220 | 170,248,147,605,750,415,321,344,136,338,22,220 | 1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,1.0095506891404633,1.8526312438376766,1.0399612405003023,3.1065707089213883,1.417026875112562 | 2,701 |
Organophosphate ester transmembrane transporter activity | 9 | 12 | 2.336006 | 0.019491 | O15439,P41440,Q8TB61,O00400,Q99808,O43808,Q9H2D1,Q6NUK1,Q9HC21 | Functions | GO Molecular function | msigdb_gomf | 248,321,136,170,338,147,22,344,220 | 170,248,147,605,750,415,321,344,136,338,22,220 | 1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,1.0095506891404633,1.8526312438376766,1.0399612405003023,3.1065707089213883,1.417026875112562 | 2,701 |
Abnormal epidermal morphology | 7 | 16 | 2.316609 | 0.020525 | O75844,Q14574,P15924,P14923,Q06136,P98194,P02545 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 43,13,14,16,18,178,214 | 2456,43,1947,214,16,14,252,2605,636,1187,676,178,18,13,1191,1239 | -1.0109701322777465,2.734822878575379,-0.5082402040270202,1.4308934785310223,3.2538860606266975,3.3434324737059566,1.3044639973832475,-1.3635087831226131,0.4570917855835725,-0.03766376468274858,0.4048059034205665,1.5805599528095038,3.244826799017829,3.4311305173075413,-0.03766376468274858,-0.05710757719101301 | 2,701 |
Endoplasmic reticulum golgi intermediate compartment membrane | 15 | 19 | 2.308863 | 0.020951 | P61019,P51572,Q9Y3A6,P24390,Q10472,Q9BVK6,Q9Y3B3,P49257,Q9Y282,P49755,Q15904,Q13190,Q15363,O15260,O95070 | Localization | GO Cellular component | msigdb_gocc | 541,253,430,9,456,174,302,583,54,277,436,215,349,285,159 | 285,865,619,159,9,2356,583,277,253,541,456,801,215,349,436,174,54,430,302 | 1.1888955874119858,0.20754810800791113,0.47438206198749655,1.6992696820323683,3.6674600654956833,-0.8680821176442824,0.5258452995193653,1.2180780751359057,1.3044639973832475,0.593531179510868,0.742084510223003,0.28031310881637544,1.4308934785310223,0.9942651268493035,0.7744188751377666,1.6072235088664195,2.557425905102... | 2,701 |
Nail dysplasia | 8 | 29 | 2.307081 | 0.02105 | Q15149,P15924,P48651,O96028,P16615,P51812,O95202,P42892 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 198,14,175,210,252,372,405,155 | 414,1174,1977,405,210,563,14,252,685,981,850,1343,1740,1413,155,175,372,1613,1860,1290,198,780,1190,2369,1758,1165,1623,1095,933 | 0.8224740869191085,-0.03766376468274858,-0.5298892096352652,0.8383751777967641,1.4447157506111374,0.559819657694308,3.3434324737059566,1.3044639973832475,0.38723710682081225,0.11485486211702632,0.22585325728994807,-0.1357571511500396,-0.3805374686703146,-0.1756174312141384,1.7122602692585014,1.5939123156550052,0.932578... | 2,701 |
Inorganic anion transmembrane transporter activity | 14 | 20 | 2.297243 | 0.021605 | O15439,O43681,Q9Y277,Q9BXP2,Q4KMQ2,P04920,Q9Y6M7,Q9UBX3,Q9C0H2,P33527,P51790,P21796,P45880,Q02978 | Functions | GO Molecular function | msigdb_gomf | 248,536,166,359,518,462,143,47,94,348,280,62,28,183 | 2227,248,536,462,62,348,28,280,813,183,518,1961,1836,566,359,94,47,166,2099,143 | -0.7296754780456444,1.3186955452496854,0.593531179510868,0.7258267538427401,2.460444745964291,0.9942651268493035,2.905147117866422,1.203511402271728,0.2622351395530162,1.540253330753097,0.6269838228448695,-0.5082402040270202,-0.4226942464977029,0.559819657694308,0.9635315701724516,2.1321287594832308,2.6626661752675664,... | 2,701 |
Sensorimotor neuropathy | 13 | 29 | 2.292042 | 0.021903 | P00403,P07602,P41440,O60313,O00429,O95831,Q15120,Q9NR77,Q9NZJ7,Q9NSE4,P05023,Q9Y2R0,Q8N2K0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 251,31,321,189,434,297,333,113,146,403,243,24,188 | 434,2071,189,297,251,243,1494,31,2217,1249,2659,1885,321,1253,1534,2341,2342,2028,1543,333,597,188,1400,2035,113,403,146,24,469 | 0.7744188751377666,-0.5954826549590951,1.5131717487404053,1.1447500131709183,1.3044639973832475,1.332880448717388,-0.23609532189713084,2.8458055936098234,-0.707024253971549,-0.07663805632366444,-1.8040386577143217,-0.4652592172226013,1.085181098032962,-0.07663805632366444,-0.25644127155135765,-0.8447106696636559,-0.844... | 2,701 |
Specific granule | 9 | 28 | 2.291804 | 0.021917 | Q08722,P30519,Q07065,Q4KMQ2,P14923,O00264,P51790,Q9Y5K8,Q6IAA8 | Localization | GO Cellular component | msigdb_gocc | 354,66,263,518,16,308,280,452,446 | 863,1465,308,1145,1495,16,911,66,1008,280,1213,263,354,529,1220,1717,1508,518,1226,446,704,921,843,2125,706,1516,788,452 | 0.20754810800791113,-0.21584326062426626,1.115067853889435,-0.01830586786658518,-0.23609532189713084,3.2538860606266975,0.17070624531058928,2.416626861835804,0.0960781397108018,1.203511402271728,-0.05710757719101301,1.2758597586554565,0.9789255457318856,0.6102896170952945,-0.05710757719101301,-0.3596097669606752,-0.236... | 2,701 |
Cristae formation | 7 | 9 | 2.288993 | 0.02208 | Q16891,Q6UXV4,Q5XKP0,Q9Y512,Q9Y4W6,Q9BUR5,O95202 | Processes and pathways | GO Biological process | msigdb_gobp | 388,200,273,212,469,186,405 | 405,388,273,200,186,475,1335,469,212 | 0.8383751777967641,0.8857323527866384,1.2470652835370355,1.4859193366122214,1.540253330753097,0.7095080229146791,-0.11596206747168612,0.7258267538427401,1.4447157506111374 | 2,701 |
Protein transmembrane transport | 14 | 22 | 2.275226 | 0.022892 | Q9NS69,Q99595,Q9UGP8,Q9BVV7,Q3ZCQ8,P61619,Q15629,O95831,O96008,O14925,O75381,Q15388,P49755,Q07820 | Processes and pathways | GO Biological process | msigdb_gobp | 2,3,515,390,417,169,41,297,326,196,339,498,277,510 | 196,712,339,684,297,326,2654,980,277,516,1638,2142,169,510,498,41,417,3,390,2178,2,515 | 1.4859193366122214,0.351885919191322,1.0247826043693027,0.38723710682081225,1.1447500131709183,1.0701601286370668,-1.746524104659968,0.11485486211702632,1.2180780751359057,0.6269838228448695,-0.3180510829696362,-0.6397609283995005,1.6469125414193932,0.6436142777409396,0.6601814574178648,2.745032234471493,0.822474086919... | 2,701 |
Basal part of cell | 19 | 49 | 2.272924 | 0.023031 | Q9H2H9,P15924,Q9Y6M7,P57105,P07355,P41440,P35222,P04920,Q99808,P33527,P11166,P58107,P42785,P05023,O15439,O75955,P53985,Q14254,P35613 | Localization | GO Cellular component | msigdb_gocc | 138,14,143,315,313,321,73,462,338,348,222,101,109,243,248,495,254,383,381 | 976,1465,1069,248,1975,495,937,808,890,462,243,1118,313,1044,960,222,1530,1245,1634,14,1701,1024,699,1879,348,73,381,321,109,254,624,315,101,677,2645,1890,529,1784,1785,1891,383,839,2151,1231,338,2156,138,681,143 | 0.11485486211702632,-0.21584326062426626,0.03925969392486323,1.3186955452496854,-0.5298892096352652,0.6601814574178648,0.15216824938562942,0.2622351395530162,0.18916598311737365,0.7258267538427401,1.332880448717388,0.000966854535827841,1.1001502232099265,0.05828124665914992,0.13355134211590133,1.4031156606893533,-0.256... | 2,701 |
Sphingolipid biosynthetic process | 6 | 14 | 2.267813 | 0.023341 | Q99805,O95470,P04062,Q06136,Q13510,Q96G23 | Processes and pathways | GO Biological process | msigdb_gobp | 202,144,177,18,119,27 | 1972,2071,144,177,797,18,119,1509,596,27,202,504,208,1168 | -0.5298892096352652,-0.5954826549590951,1.7893924505266094,1.5805599528095038,0.28031310881637544,3.244826799017829,1.951920624080694,-0.23609532189713084,0.5087582951969946,2.92474561480173,1.4859193366122214,0.6601814574178648,1.4722284064322555,-0.01830586786658518 | 2,701 |
Intrinsic component of plasma membrane | 42 | 76 | 2.260041 | 0.023819 | O15118,Q96QD8,P35613,Q9H2H9,Q9UJS0,Q9UIQ6,P51790,Q9UNK0,Q9Y289,O00400,Q00325,O00264,P10321,Q02978,Q99797,Q8N2K0,P17152,P27824,Q8WTV0,P41440,Q9BTU6,Q99805,O60637,Q99808,P11279,Q92542,O96005,P33527,P11166,Q08722,P05141,Q13641,O95864,Q9NR28,Q9H0U3,O43657,P05023,O76062,P54709,P53985,P16615,P51572 | Localization | GO Cellular component | msigdb_gocc | 130,389,381,138,666,142,280,282,681,170,551,308,563,183,317,188,320,570,322,321,324,202,77,338,80,599,85,348,222,354,605,355,479,489,238,107,243,620,624,254,252,253 | 1277,308,170,935,1811,1693,130,865,107,848,77,620,479,85,808,2105,243,1118,605,1043,563,1149,222,80,1601,750,252,320,1701,1024,1314,699,570,348,1920,381,1098,321,2574,253,280,254,624,677,551,183,354,801,1647,355,2390,2002,1129,839,842,1658,188,1296,921,1836,322,599,389,317,202,338,324,238,138,489,142,666,282,681,2133,8... | -0.09625596283480581,1.115067853889435,1.6337233768883894,0.15216824938562942,-0.4226942464977029,-0.3596097669606752,1.8901336133115505,0.20754810800791113,2.0489706294219476,0.22585325728994807,2.2824196152272136,0.47438206198749655,0.6931278673873417,2.213707758412066,0.2622351395530162,-0.6175661397525806,1.3328804... | 2,701 |
Cardiac muscle contraction | 8 | 19 | 2.259403 | 0.023858 | P00403,P14406,O14949,P10606,P31930,P05023,Q9UDW1,P16615 | Processes and pathways | KEGG Pathways | msigdb_kegg | 251,1,65,298,81,243,118,252 | 65,251,243,1118,796,749,2505,1950,298,343,1,1471,252,1076,569,81,624,1643,118 | 2.4276234185896435,1.3044639973832475,1.332880448717388,0.000966854535827841,0.28031310881637544,0.31624613864460677,-1.1088623151263601,-0.5082402040270202,1.1447500131709183,1.0095506891404633,5.210648084460358,-0.21584326062426626,1.3044639973832475,0.03925969392486323,0.5428655840352268,2.248201202031891,0.47438206... | 2,701 |
Sulfur compound transport | 8 | 11 | 2.252964 | 0.024261 | Q8TB61,Q70HW3,O00400,Q9UBX3,O15439,Q9HC21,P33527,Q02978 | Processes and pathways | GO Biological process | msigdb_gobp | 136,11,170,47,248,220,348,183 | 170,248,348,183,11,136,1836,450,220,47,681 | 1.6337233768883894,1.3186955452496854,0.9942651268493035,1.540253330753097,3.617915206963102,1.8526312438376766,-0.4226942464977029,0.7582817372111945,1.417026875112562,2.6626661752675664,0.4048059034205665 | 2,701 |
Rhoa gtpase cycle | 15 | 38 | 2.243373 | 0.024873 | O15173,P41440,P30519,Q8NBN3,Q96HY6,O75955,P14923,Q14739,Q15904,Q13190,P42167,Q9H0H5,P28288,Q14254,P51572 | Processes and pathways | Reactome Pathways | msigdb_reactome | 127,321,66,90,270,495,16,53,436,215,379,450,470,383,253 | 863,1810,127,865,2209,495,1117,808,980,16,470,66,321,1923,379,985,583,253,1446,2360,215,2287,383,53,436,2086,842,90,2090,2241,690,270,450,2371,514,2095,1197,1462 | 0.20754810800791113,-0.4226942464977029,1.9025621688075542,0.20754810800791113,-0.707024253971549,0.6601814574178648,0.000966854535827841,0.2622351395530162,0.11485486211702632,3.2538860606266975,0.7095080229146791,2.416626861835804,1.085181098032962,-0.4866972109565579,0.9170194617840494,0.11485486211702632,0.52584529... | 2,701 |
Atpase coupled transmembrane transporter activity | 11 | 22 | 2.24246 | 0.024932 | P98194,P08183,P05023,P33527,O15439,Q9Y5K8,Q9HD20,P61421,P28288,P16615,O75027 | Functions | GO Molecular function | msigdb_gomf | 178,180,243,348,248,452,58,471,470,252,371 | 248,371,243,1118,1568,180,252,1024,1343,1602,699,470,348,1882,2191,813,471,178,498,58,1433,452 | 1.3186955452496854,0.9325789136855012,1.332880448717388,0.000966854535827841,-0.27688196692354466,1.5537307142177417,1.3044639973832475,0.07722049678650203,-0.1357571511500396,-0.2974182770678407,0.36959730040846983,0.7095080229146791,0.9942651268493035,-0.4652592172226013,-0.6844888552895658,0.2622351395530162,0.70950... | 2,701 |
Sparse or absent eyelashes | 7 | 23 | 2.235871 | 0.02536 | O75844,Q14574,P15924,P14923,Q9H9Y6,P48449,P02545 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 43,13,14,16,306,83,214 | 1020,2298,1174,2314,43,214,1631,16,14,621,1571,1252,83,1449,1993,2144,1648,13,2536,1165,306,1623,318 | 0.07722049678650203,-0.7983359233670255,-0.03766376468274858,-0.8214623601730139,2.734822878575379,1.4308934785310223,-0.3180510829696362,3.2538860606266975,3.3434324737059566,0.47438206198749655,-0.27688196692354466,-0.07663805632366444,2.2367341600459416,-0.19568424190462033,-0.5298892096352652,-0.6397609283995005,-0... | 2,701 |
ER-Golgi transport | 17 | 49 | 2.234406 | 0.025456 | O95249,P51572,O14579,P62820,O95197,P24390,Q9Y678,Q9HCU5,O95487,Q9NR31,Q9Y282,P49755,Q9P2W9,Q12981,Q969M3,Q15363,O95070 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 225,253,293,517,10,9,106,534,304,275,54,277,181,543,376,349,159 | 293,1374,865,1241,1595,1974,619,1770,159,10,225,1567,304,1150,9,1499,1924,583,277,253,1674,1477,1992,2196,1009,541,1154,517,543,1323,349,2084,1161,1355,1035,1546,1106,1134,2090,1400,376,2175,534,275,181,765,54,2330,106 | 1.1595152238833708,-0.1556420051329787,0.20754810800791113,-0.07663805632366444,-0.2974182770678407,-0.5298892096352652,0.47438206198749655,-0.40156531384122846,1.6992696820323683,3.6262130177039786,1.3891595529580087,-0.27688196692354466,1.1299343362894672,-0.01830586786658518,3.6674600654956833,-0.23609532189713084,-... | 2,701 |
Establishment of protein localization to mitochondrial membrane | 6 | 15 | 2.232867 | 0.025558 | Q9NS69,Q9P0J0,Q8WWC4,Q9Y5J9,Q9Y512,Q15070 | Processes and pathways | GO Biological process | msigdb_gobp | 2,133,140,209,212,56 | 696,826,684,1176,1497,2110,56,596,140,2,133,617,212,276,209 | 0.36959730040846983,0.24408206050486364,0.38723710682081225,-0.03766376468274858,-0.23609532189713084,-0.6175661397525806,2.5360636019540204,0.5087582951969946,1.8147994633249862,5.159139452386764,1.8901336133115505,0.49160405626708076,1.4447157506111374,1.2325959289574466,1.4722284064322555 | 2,701 |
Nucleobase containing compound transmembrane transporter activity | 9 | 14 | 2.224952 | 0.026084 | O15439,P41440,Q8TB61,O00400,Q99808,O43808,Q9H2D1,Q6NUK1,Q9HC21 | Functions | GO Molecular function | msigdb_gomf | 248,321,136,170,338,147,22,344,220 | 825,170,248,147,605,750,415,321,591,344,136,338,22,220 | 0.24408206050486364,1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,0.5087582951969946,1.0095506891404633,1.8526312438376766,1.0399612405003023,3.1065707089213883,1.417026875112562 | 2,701 |
Microbody membrane | 12 | 23 | 2.22279 | 0.02623 | O15228,Q15067,Q9BY49,P50542,Q8TB36,Q9NR77,Q8NBU5,O75381,O43808,P28288,P51648,P40855 | Localization | GO Cellular component | msigdb_gocc | 289,259,99,516,244,113,402,339,147,470,218,572 | 934,289,147,1309,339,1437,2019,470,1248,1571,572,516,218,1534,259,585,917,402,244,902,2174,99,113 | 0.15216824938562942,1.1742303044100273,1.7638347606018192,-0.11596206747168612,1.0247826043693027,-0.19568424190462033,-0.5516452556198194,0.7095080229146791,-0.07663805632366444,-0.27688196692354466,0.5428655840352268,0.6269838228448695,1.417026875112562,-0.25644127155135765,1.2901855033977274,0.5258452995193653,0.170... | 2,701 |
Oxidoreduction driven active transmembrane transporter activity | 12 | 29 | 2.215183 | 0.026747 | P00403,O96000,O43676,Q9P0J0,O95169,O95168,P10606,P31930,Q9UDW1,P13073,Q7KZN9,Q9Y6M9 | Functions | GO Molecular function | msigdb_gomf | 251,290,4,133,295,325,298,81,118,343,152,30 | 2556,1115,4,1973,2516,478,1528,2230,325,295,2442,2017,290,251,749,298,343,2561,1076,2046,81,2608,1256,399,609,152,133,118,30 | -1.2089703136081216,0.000966854535827841,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,1.1742303044100273,1.3044639973832475,0.31624613864460677,1.1447500131709183,1.00955... | 2,701 |
Protein transmembrane transporter activity | 8 | 10 | 2.213162 | 0.026886 | Q9NS69,Q99595,O96008,P61619,O14925,Q15388,P49755,Q07820 | Functions | GO Molecular function | msigdb_gomf | 2,3,326,169,196,498,277,510 | 196,684,326,277,169,510,498,3,2,515 | 1.4859193366122214,0.38723710682081225,1.0701601286370668,1.2180780751359057,1.6469125414193932,0.6436142777409396,0.6601814574178648,4.492615277702867,5.159139452386764,0.6436142777409396 | 2,701 |
Sparse eyebrow | 8 | 27 | 2.207902 | 0.027251 | O75844,Q14574,P15924,P14923,P48449,O75431,P02545,Q92643 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 43,13,14,16,83,309,214,287 | 1020,1279,309,2314,43,214,16,14,2443,621,1252,83,1448,731,1711,1449,2682,2144,1859,13,782,1326,287,439,1038,601,318 | 0.07722049678650203,-0.09625596283480581,1.115067853889435,-0.8214623601730139,2.734822878575379,1.4308934785310223,3.2538860606266975,3.3434324737059566,-0.9868321395764779,0.47438206198749655,-0.07663805632366444,2.2367341600459416,-0.19568424190462033,0.3341023914526849,-0.3596097669606752,-0.19568424190462033,-2.42... | 2,701 |
Apoptotic mitochondrial changes | 10 | 30 | 2.195223 | 0.028148 | O60313,Q16611,Q3ZCQ8,Q9NT62,O75223,Q96A26,O75832,P02545,P45880,Q9H3K2 | Processes and pathways | GO Biological process | msigdb_gobp | 189,37,417,391,261,48,303,214,28,223 | 434,826,189,261,303,214,1411,1096,605,2654,750,2046,2571,1497,636,2385,28,1985,870,37,417,1017,1396,1726,48,1232,1059,223,391,932 | 0.7744188751377666,0.24408206050486364,1.5131717487404053,1.2758597586554565,1.1299343362894672,1.4308934785310223,-0.1756174312141384,0.02015513431309902,0.49160405626708076,-1.746524104659968,0.31624613864460677,-0.5735093847387928,-1.234355168597917,-0.23609532189713084,0.4570917855835725,-0.8915779896099613,2.90514... | 2,701 |
Membrane lipid catabolic process | 6 | 11 | 2.193421 | 0.028277 | Q99735,P17900,P50897,O95470,P04062,Q13510 | Processes and pathways | GO Biological process | msigdb_gobp | 420,163,74,144,177,119 | 144,177,1022,1075,1281,829,163,74,119,420,504 | 1.7893924505266094,1.5805599528095038,0.07722049678650203,0.03925969392486323,-0.09625596283480581,0.24408206050486364,1.6862398498357258,2.3163672654572762,1.951920624080694,0.8224740869191085,0.6601814574178648 | 2,701 |
Cis golgi network | 8 | 13 | 2.192813 | 0.028321 | O95249,O00461,Q92538,Q9Y3A6,P24390,P98194,P49755,Q9NPR9 | Localization | GO Cellular component | msigdb_gocc | 225,34,358,430,9,178,277,216 | 34,1595,225,9,1498,277,178,1354,445,2090,358,216,430 | 2.815822521189644,-0.2974182770678407,1.3891595529580087,3.6674600654956833,-0.23609532189713084,1.2180780751359057,1.5805599528095038,-0.1357571511500396,0.7582817372111945,-0.5954826549590951,0.9635315701724516,1.4308934785310223,0.8065146214158287 | 2,701 |
Secondary alcohol metabolic process | 15 | 36 | 2.188018 | 0.028668 | O15118,Q15392,Q9UBM7,Q8WTV0,P16435,Q14534,P37268,P61916,P48735,Q9BQE5,P04062,P48449,Q14739,Q16850,Q15800 | Processes and pathways | GO Biological process | msigdb_gobp | 130,131,36,322,441,327,69,72,329,12,177,83,53,278,409 | 130,1490,794,1310,620,1817,1696,177,1819,940,441,2216,69,2385,83,329,455,2662,1991,72,2266,2418,2471,327,53,2220,131,594,409,278,586,322,2552,12,36,2475 | 1.8901336133115505,-0.23609532189713084,0.28031310881637544,-0.11596206747168612,0.47438206198749655,-0.4226942464977029,-0.3596097669606752,1.5805599528095038,-0.4226942464977029,0.15216824938562942,0.7582817372111945,-0.707024253971549,2.3945487262934133,-0.8915779896099613,2.2367341600459416,1.0550869617499012,0.742... | 2,701 |
Endocytic vesicle membrane | 11 | 33 | 2.184997 | 0.028889 | Q8WTV0,P51151,Q9Y487,Q12846,Q15907,P11279,Q5KU26,Q14108,P10321,Q93050,P61421 | Localization | GO Cellular component | msigdb_gocc | 322,164,134,529,266,80,597,21,563,91,471 | 863,619,713,1737,808,2105,563,80,1601,1671,1314,2356,1474,774,164,963,1350,471,1608,1611,1219,529,1506,1053,21,1129,266,597,322,91,761,926,134 | 0.20754810800791113,0.47438206198749655,0.351885919191322,-0.3805374686703146,0.2622351395530162,-0.6175661397525806,0.559819657694308,2.248201202031891,-0.2974182770678407,-0.33878127776425015,-0.11596206747168612,-0.8680821176442824,-0.21584326062426626,0.2983165752789475,1.6862398498357258,0.13355134211590133,-0.135... | 2,701 |
Ectopic calcification | 14 | 43 | 2.177439 | 0.029448 | P00403,O15228,O60313,Q9UBM7,P35222,O75844,P04062,P38435,O75381,Q14739,O75431,P02545,P23786,P11166 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 251,289,189,36,73,43,177,114,339,53,309,214,182,222 | 934,434,1766,289,2298,189,1174,2253,339,309,43,1668,251,214,177,1915,342,2256,222,2282,981,850,182,73,114,2509,572,2051,516,1534,963,1316,2387,53,1786,594,2404,1760,1623,1805,36,1239,2409 | 0.15216824938562942,0.7744188751377666,-0.40156531384122846,1.1742303044100273,-0.7983359233670255,1.5131717487404053,-0.03766376468274858,-0.7524437006538256,1.0247826043693027,1.115067853889435,2.734822878575379,-0.33878127776425015,1.3044639973832475,1.4308934785310223,1.5805599528095038,-0.4866972109565579,1.009550... | 2,701 |
Outer membrane | 38 | 78 | 2.173533 | 0.02974 | O43169,Q9NS69,Q16891,Q9NQZ5,Q5XKP0,Q9NZJ7,Q8NBU5,Q6NUM9,P45880,Q8N4H5,Q9UBM7,Q16611,Q9Y277,Q13505,Q709C8,O00264,O75431,Q9BUR5,O00429,P57105,P21796,Q96TC7,O60313,P30536,Q6UXV4,Q99536,O96008,Q15149,P50402,Q9Y512,Q9BUK6,Q9NVH1,Q9Y6C9,Q99720,Q8TB36,Q99623,Q9NXE4,Q15388 | Localization | GO Cellular component | msigdb_gocc | 0,2,388,265,273,146,402,151,28,32,36,37,166,296,173,308,309,186,434,315,62,64,189,195,200,323,326,198,197,212,211,475,92,501,244,245,504,498 | 308,434,2698,0,189,1309,309,684,1437,326,1696,2211,715,672,1246,62,195,1248,2632,2594,912,1825,28,2574,197,870,2342,315,2167,510,1542,296,2267,198,498,37,388,596,817,273,151,200,173,917,545,1017,1396,1456,32,969,402,244,649,1230,950,64,323,245,501,211,186,1059,727,2588,265,693,2,1234,475,1335,504,146,36,1065,166,1522,2... | 1.115067853889435,0.7744188751377666,-4.819863517888487,5.210648084460358,1.5131717487404053,-0.11596206747168612,1.115067853889435,0.38723710682081225,-0.19568424190462033,1.0701601286370668,-0.3596097669606752,-0.707024253971549,0.351885919191322,0.4048059034205665,-0.07663805632366444,2.460444745964291,1.49956702839... | 2,701 |
Golgi associated vesicle | 8 | 28 | 2.172273 | 0.029835 | O14579,P24390,Q9Y678,Q9BVK6,Q9Y3B3,P49755,Q8TCT8,Q15363 | Localization | GO Cellular component | msigdb_gocc | 293,9,106,174,302,277,250,349 | 293,1376,1737,2188,698,1601,9,1499,983,1924,277,675,1674,1477,1350,416,1154,1611,1219,349,250,2090,174,1802,1521,765,302,106 | 1.1595152238833708,-0.1556420051329787,-0.3805374686703146,-0.6844888552895658,0.36959730040846983,-0.2974182770678407,3.6674600654956833,-0.23609532189713084,0.11485486211702632,-0.4866972109565579,1.2180780751359057,0.4048059034205665,-0.33878127776425015,-0.21584326062426626,-0.1357571511500396,0.8224740869191085,-0... | 2,701 |
Skin nodule | 13 | 20 | 2.168734 | 0.030103 | P11802,Q9NZ08,P48735,P35222,P35637,Q13510,Q9Y2U8,Q9NSE4,P16615,Q8NBM4,P21912,P31749,P52732 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 606,360,329,73,364,119,806,403,252,738,314,636,676 | 1310,1075,606,252,314,636,73,364,329,812,676,1219,1081,119,1161,738,1299,403,360,806 | -0.11596206747168612,0.03925969392486323,0.49160405626708076,1.3044639973832475,1.1001502232099265,0.4570917855835725,2.3276237027439657,0.9480828206502808,1.0550869617499012,0.2622351395530162,0.4048059034205665,-0.05710757719101301,0.03925969392486323,1.951920624080694,-0.01830586786658518,0.3341023914526849,-0.09625... | 2,701 |
Mitochondrial transport | 30 | 73 | 2.16844 | 0.030125 | Q9NS69,Q99595,Q9P0J0,Q9BVV7,Q8WWC4,P55786,Q9Y5J7,P56385,P45880,Q8N4H5,Q10713,Q16611,Q3ZCQ8,O95831,Q5JRX3,Q9UBX3,O75431,Q15070,Q99797,P23786,O75964,P30536,O96008,O14925,Q9Y5J9,Q9Y512,Q6NUK1,O43772,Q8TB36,P51572 | Processes and pathways | GO Biological process | msigdb_gobp | 2,3,133,390,140,17,276,407,28,32,161,37,417,297,425,47,309,56,317,182,57,195,326,196,209,212,344,103,244,253 | 1306,826,196,712,103,309,1493,2015,57,684,1771,297,326,1096,605,1568,1176,715,2654,750,2636,182,622,2337,2571,1497,195,2110,1777,2385,28,2573,583,2574,253,870,17,2306,407,2319,161,56,498,37,417,596,425,344,992,1017,1396,32,244,140,439,1232,1839,3,317,390,1059,2178,2,133,2069,47,666,766,617,1522,212,276,209 | -0.11596206747168612,0.24408206050486364,1.4859193366122214,0.351885919191322,2.060949321084514,1.115067853889435,-0.23609532189713084,-0.5516452556198194,2.5038189105500694,0.38723710682081225,-0.40156531384122846,1.1447500131709183,1.0701601286370668,0.02015513431309902,0.49160405626708076,-0.27688196692354466,-0.037... | 2,701 |
Alopecia | 8 | 37 | 2.166382 | 0.030282 | Q15149,O75844,P15924,P14923,Q06136,P48449,O75431,P02545 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 198,43,14,16,18,83,309,214 | 312,1174,1814,309,43,1668,526,214,1631,1915,16,14,685,981,850,1413,1252,83,2660,1449,1783,18,1450,457,1223,198,594,1190,1191,2270,1165,2273,1689,1623,2037,2582,617 | 1.1001502232099265,-0.03766376468274858,-0.4226942464977029,1.115067853889435,2.734822878575379,-0.33878127776425015,0.6102896170952945,1.4308934785310223,-0.3180510829696362,-0.4866972109565579,3.2538860606266975,3.3434324737059566,0.38723710682081225,0.11485486211702632,0.22585325728994807,-0.1756174312141384,-0.0766... | 2,701 |
Outer mitochondrial membrane protein complex | 12 | 16 | 2.159346 | 0.030823 | Q9NS69,Q16891,Q6UXV4,Q13505,O96008,Q5XKP0,Q9Y512,Q15388,O75431,Q9BUR5,Q9NVH1,Q8N4H5 | Localization | GO Cellular component | msigdb_gocc | 2,388,200,296,326,273,212,498,309,186,475,32 | 309,684,326,2594,296,498,388,273,200,545,32,186,2,475,1335,212 | 1.115067853889435,0.38723710682081225,1.0701601286370668,-1.3373751235719122,1.1595152238833708,0.6601814574178648,0.8857323527866384,1.2470652835370355,1.4859193366122214,0.593531179510868,2.8458055936098234,1.540253330753097,5.159139452386764,0.7095080229146791,-0.11596206747168612,1.4447157506111374 | 2,701 |
Purine nucleotide transmembrane transporter activity | 7 | 10 | 2.144273 | 0.032011 | O15439,P41440,Q8TB61,O00400,Q99808,O43808,Q6NUK1 | Functions | GO Molecular function | msigdb_gomf | 248,321,136,170,338,147,344 | 170,248,147,605,750,415,321,344,136,338 | 1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,1.0095506891404633,1.8526312438376766,1.0399612405003023 | 2,701 |
Abnormality of the larynx | 13 | 42 | 2.143506 | 0.032072 | P07602,Q9UBM7,Q99700,Q9UHX1,P35637,Q96HY6,Q9NZJ7,P21964,Q14739,P02545,Q13510,Q15165,Q92804 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 31,36,201,362,364,270,146,82,53,214,119,125,447 | 1020,2253,1117,214,1096,31,1597,1599,441,1740,82,717,364,1882,1883,2263,1704,1185,1008,1476,1992,2341,1011,1478,119,678,53,1127,125,2536,1960,1656,1618,2525,447,1485,270,201,146,2037,36,362 | 0.07722049678650203,-0.7524437006538256,0.000966854535827841,1.4308934785310223,0.02015513431309902,2.8458055936098234,-0.2974182770678407,-0.2974182770678407,0.7582817372111945,-0.3805374686703146,2.2367341600459416,0.351885919191322,0.9480828206502808,-0.4652592172226013,-0.4652592172226013,-0.7524437006538256,-0.359... | 2,701 |
Phagocytic vesicle | 11 | 34 | 2.138075 | 0.032511 | P61106,P51151,Q9Y487,Q12846,Q15907,P11279,P51790,Q93050,Q9UNK0,P61421,P08670 | Localization | GO Cellular component | msigdb_gocc | 416,164,134,529,266,80,280,91,282,471,286 | 976,863,1465,1203,1071,2253,619,2105,286,563,80,1671,2356,2262,1182,912,1474,1008,774,164,280,1448,1350,416,471,1219,529,1053,266,721,91,926,282,134 | 0.11485486211702632,0.20754810800791113,-0.21584326062426626,-0.05710757719101301,0.03925969392486323,-0.7524437006538256,0.47438206198749655,-0.6175661397525806,1.1888955874119858,0.559819657694308,2.248201202031891,-0.33878127776425015,-0.8680821176442824,-0.7524437006538256,-0.03766376468274858,0.17070624531058928,-... | 2,701 |
Muscle abnormality related to mitochondrial dysfunction | 9 | 27 | 2.134291 | 0.032819 | P00403,O96000,O60313,O43676,Q86Y39,Q9UBX3,Q9BUK6,Q9Y2R0,Q9Y6M9 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 251,290,189,4,104,47,211,24,30 | 2556,1115,4,189,2516,478,1528,398,290,251,750,2561,2046,1825,2608,2195,596,104,2367,1138,211,307,1235,47,24,1170,30 | -1.2089703136081216,0.000966854535827841,4.14073910845815,1.5131717487404053,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,0.8542183112675076,1.1742303044100273,1.3044639973832475,0.31624613864460677,-1.2089703136081216,-0.5735093847387928,-0.4226942464977029,-1.3635087831226131,-0.6844888552895658,0.5087... | 2,701 |
Class i peroxisomal membrane protein import | 7 | 8 | 2.134271 | 0.032821 | Q8TB36,Q9NR77,Q8NBU5,O75381,O43808,P51648,P28288 | Processes and pathways | Reactome Pathways | msigdb_reactome | 244,113,402,339,147,218,470 | 147,339,470,572,218,402,244,113 | 1.7638347606018192,1.0247826043693027,0.7095080229146791,0.5428655840352268,1.417026875112562,0.8542183112675076,1.332880448717388,2.024912659220012 | 2,701 |
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen | 13 | 28 | 2.1303 | 0.033147 | Q32P28,P13674,Q9BU89,O60568,P30519,Q6UW02,P16435,Q8NB78,Q14534,O00767,Q16850,Q15800,O15460 | Functions | GO Molecular function | msigdb_gomf | 472,257,67,414,66,165,441,427,327,335,278,409,312 | 2679,335,312,1279,414,2229,1469,479,979,672,257,441,1820,66,1318,1645,1262,327,409,278,472,1417,165,2522,427,67,1366,1067 | -2.3580812473620907,1.0399612405003023,1.1001502232099265,-0.09625596283480581,0.8224740869191085,-0.7296754780456444,-0.21584326062426626,0.6931278673873417,0.11485486211702632,0.4048059034205665,1.2901855033977274,0.7582817372111945,-0.4226942464977029,2.416626861835804,-0.11596206747168612,-0.3180510829696362,-0.076... | 2,701 |
Macromolecule transmembrane transporter activity | 8 | 11 | 2.122153 | 0.033825 | Q9NS69,Q99595,O96008,P61619,O14925,Q15388,P49755,Q07820 | Functions | GO Molecular function | msigdb_gomf | 2,3,326,169,196,498,277,510 | 196,684,326,277,591,169,510,498,3,2,515 | 1.4859193366122214,0.38723710682081225,1.0701601286370668,1.2180780751359057,0.5087582951969946,1.6469125414193932,0.6436142777409396,0.6601814574178648,4.492615277702867,5.159139452386764,0.6436142777409396 | 2,701 |
Endoplasmic reticulum membrane organization | 6 | 8 | 2.118208 | 0.034157 | Q8NHH9,Q00765,Q9P2W9,Q12981,Q9NQC3,Q15363 | Processes and pathways | GO Biological process | msigdb_gobp | 512,395,181,543,122,349 | 1117,395,543,349,586,512,122,181 | 0.000966854535827841,0.8700039001223019,0.593531179510868,0.9942651268493035,0.5258452995193653,0.6436142777409396,1.93963397583531,1.5537307142177417 | 2,701 |
Purine nucleotide transport | 8 | 12 | 2.109385 | 0.034911 | O15439,Q08722,P41440,Q8TB61,O00400,Q99808,O43808,Q6NUK1 | Processes and pathways | GO Biological process | msigdb_gobp | 248,354,321,136,170,338,147,344 | 170,248,147,605,750,415,321,354,344,136,1836,338 | 1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,0.9789255457318856,1.0095506891404633,1.8526312438376766,-0.4226942464977029,1.0399612405003023 | 2,701 |
Organelle fusion | 21 | 39 | 2.106366 | 0.035173 | Q12846,Q12981,Q9UNK0,Q8IWA4,O95721,P51153,Q16611,P06493,O15400,Q9H269,P07355,O60313,Q99536,Q86Y82,Q9Y4W6,Q13190,Q9Y6C9,O95249,Q8TB36,Q969M3,O75396 | Processes and pathways | GO Biological process | msigdb_gobp | 529,543,282,545,538,675,37,562,561,707,313,189,323,721,469,215,92,225,244,376,619 | 863,561,189,866,1974,619,225,538,808,890,562,313,1002,774,675,1350,529,543,215,37,992,721,545,244,1086,376,323,1059,707,2588,1335,1589,2407,766,1909,282,2039,469,92 | 0.20754810800791113,0.559819657694308,1.5131717487404053,0.20754810800791113,-0.5298892096352652,0.47438206198749655,1.3891595529580087,0.593531179510868,0.2622351395530162,0.18916598311737365,0.559819657694308,1.1001502232099265,0.0960781397108018,0.2983165752789475,0.4048059034205665,-0.1357571511500396,0.61028961709... | 2,701 |
Metalloprotease | 11 | 26 | 2.098587 | 0.035853 | P09960,O43847,Q9NZ08,O75844,Q5JRX3,Q9UIQ6,P55786,Q96TA2,Q9Y4W6,Q99797,P42892 | Functions | Protein Atlas Molecular function | protein_atlas_molecular_function | 226,486,360,43,425,142,17,500,469,317,155 | 1913,486,1493,43,1470,714,226,2642,1245,155,1535,17,425,880,1796,2091,500,317,533,1369,1331,1370,1040,360,142,469 | -0.4866972109565579,0.676685832241666,-0.23609532189713084,2.734822878575379,-0.21584326062426626,0.351885919191322,1.3891595529580087,-1.6336795739285952,-0.07663805632366444,1.7122602692585014,-0.25644127155135765,3.244826799017829,0.8065146214158287,0.20754810800791113,-0.40156531384122846,-0.5954826549590951,0.6601... | 2,701 |
Translocation | 14 | 45 | 2.095182 | 0.036155 | Q9NS69,Q99595,Q9BVV7,Q3ZCQ8,P61619,Q15629,Q92621,Q12769,O14925,Q9Y5J9,Q9Y5J7,Q9BTX1,O75381,Q8NFH4 | Processes and pathways | Protein Atlas Biological process | protein_atlas_biological_process | 2,3,390,417,169,41,428,487,196,209,276,148,339,249 | 976,196,712,339,1001,1177,1604,2050,1887,851,2112,1009,835,1638,169,2167,1782,487,41,417,1015,782,1897,647,249,1756,2291,1898,1514,1684,428,1869,1459,3,148,1799,390,611,514,2,1729,1590,2096,276,209 | 0.11485486211702632,1.4859193366122214,0.351885919191322,1.0247826043693027,0.0960781397108018,-0.03766376468274858,-0.2974182770678407,-0.5735093847387928,-0.4652592172226013,0.22585325728994807,-0.6175661397525806,0.0960781397108018,0.24408206050486364,-0.3180510829696362,1.6469125414193932,-0.6620681262993946,-0.401... | 2,701 |
Inner mitochondrial membrane protein complex | 34 | 70 | 2.093494 | 0.036305 | P00403,P14406,Q99595,O43676,Q9P0J0,Q9BVV7,Q16891,Q16718,Q5XKP0,Q9Y5J7,P56385,Q9Y6M9,O96000,Q13505,Q3ZCQ8,P12236,O95169,P10606,O75431,Q9BUR5,O75964,P21912,O14949,Q6UXV4,O95168,O14925,P31930,Q9Y512,Q9Y4W6,P13073,Q9NVH1,Q86Y39,Q99623,Q9UDW1 | Localization | GO Cellular component | msigdb_gocc | 251,1,3,4,133,390,388,399,273,276,407,30,290,296,417,415,295,298,309,186,57,314,65,200,325,196,81,212,469,343,475,104,245,118 | 2556,1115,196,65,4,1973,2516,478,309,1528,2015,57,2230,325,295,2442,2017,290,251,1568,749,1950,298,415,343,1,1471,2561,1076,314,569,622,2337,2046,2397,81,1920,1777,2594,2573,2608,1256,2306,407,296,399,609,388,417,596,273,200,104,598,742,3,245,906,186,390,2178,475,1335,133,118,617,469,212,276,30 | -1.2089703136081216,0.000966854535827841,1.4859193366122214,2.4276234185896435,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,1.115067853889435,-0.25644127155135765,-0.5516452556198194,2.5038189105500694,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.551645... | 2,701 |
Endoplasmic reticulum to golgi vesicle mediated transport | 24 | 62 | 2.085024 | 0.037067 | Q8NHH9,P62820,P24390,Q9HCU5,O75340,Q9NR31,P49755,O95070,O14579,Q9Y3A6,Q9BVK6,Q9Y3B3,O95487,Q9Y282,Q9P2W9,Q96PC5,Q13190,Q7Z7H5,Q15363,O95249,Q92538,Q9Y678,Q969M3,P51572 | Processes and pathways | GO Biological process | msigdb_gobp | 512,517,9,534,272,275,277,159,293,430,174,302,304,54,181,328,215,219,349,225,358,106,376,253 | 1407,293,1374,865,1241,1595,1974,272,619,1770,159,225,1117,1567,304,1150,9,1499,1924,583,277,253,1674,1477,1992,2341,1009,541,517,801,215,1323,349,2084,1161,1355,1035,1546,219,1106,512,2090,358,1400,376,328,174,534,1802,275,1168,181,765,1967,1236,54,2330,430,302,2248,106,711 | -0.1756174312141384,1.1595152238833708,-0.1556420051329787,0.20754810800791113,-0.07663805632366444,-0.2974182770678407,-0.5298892096352652,1.2470652835370355,0.47438206198749655,-0.40156531384122846,1.6992696820323683,1.3891595529580087,0.000966854535827841,-0.27688196692354466,1.1299343362894672,-0.01830586786658518,... | 2,701 |
Biliary tract abnormality | 13 | 24 | 2.083721 | 0.037186 | P07602,Q10713,O43681,P50542,Q93008,Q5XKP0,Q9NZJ7,P04062,Q14739,Q14108,O96028,P02545,O95202 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 31,161,536,516,557,273,146,177,53,21,210,214,405 | 536,405,210,214,177,31,672,716,2570,1883,516,1534,161,2168,1613,21,53,273,557,1760,146,1560,617,997 | 0.593531179510868,0.8383751777967641,1.4447157506111374,1.4308934785310223,1.5805599528095038,2.8458055936098234,0.4048059034205665,0.351885919191322,-1.234355168597917,-0.4652592172226013,0.6269838228448695,-0.25644127155135765,1.6992696820323683,-0.6620681262993946,-0.2974182770678407,3.1159288248830843,2.55742590510... | 2,701 |
Protein localization to endoplasmic reticulum | 9 | 29 | 2.072975 | 0.038175 | Q9NQC3,P61619,P24390,Q15629,P61009,Q96HY6,Q15005,Q9Y5M8,P51572 | Processes and pathways | GO Biological process | msigdb_gobp | 122,169,9,41,299,270,316,158,253 | 1374,523,536,1489,1205,2281,961,9,1572,1210,2166,253,1638,2052,299,2142,169,316,41,1355,2691,738,358,270,122,1168,515,1198,158 | -0.1556420051329787,0.6102896170952945,0.593531179510868,-0.23609532189713084,-0.05710757719101301,-0.7753301127313307,0.13355134211590133,3.6674600654956833,-0.27688196692354466,-0.05710757719101301,-0.6620681262993946,1.3044639973832475,-0.3180510829696362,-0.5735093847387928,1.1447500131709183,-0.6397609283995005,1.... | 2,701 |
Polyneuropathy | 7 | 15 | 2.071453 | 0.038316 | P07602,O60313,O95831,P31930,Q9NZJ7,Q9HC21,Q8N2K0 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 31,189,297,81,146,220,188 | 189,538,297,1022,31,2282,621,81,1011,333,879,188,220,146,1907 | 1.5131717487404053,0.593531179510868,1.1447500131709183,0.07722049678650203,2.8458055936098234,-0.7753301127313307,0.47438206198749655,2.248201202031891,0.0960781397108018,1.0550869617499012,0.20754810800791113,1.526733762162025,1.417026875112562,1.7766325496335293,-0.4652592172226013 | 2,701 |
metalloprotease | 13 | 25 | 2.070203 | 0.038433 | Q10713,O43847,Q9NZ08,O75844,Q5JRX3,Q9UIQ6,Q9BYT8,P55786,P31930,Q96TA2,Q9Y4W6,Q99797,P42892 | Functions | Panther Protein class | panther_protein_class | 161,486,360,43,425,142,533,17,81,500,469,317,155 | 486,1493,43,714,808,2642,1245,569,2508,81,155,1535,17,161,425,880,2091,500,317,533,1331,1040,360,142,469 | 0.676685832241666,-0.23609532189713084,2.734822878575379,0.351885919191322,0.2622351395530162,-1.6336795739285952,-0.07663805632366444,0.5428655840352268,-1.1088623151263601,2.248201202031891,1.7122602692585014,-0.25644127155135765,3.244826799017829,1.6992696820323683,0.8065146214158287,0.20754810800791113,-0.595482654... | 2,701 |
Subcutaneous nodule | 12 | 18 | 2.053651 | 0.040009 | Q9NZ08,P11802,P48735,P35222,P35637,Q13510,Q9Y2U8,Q9NSE4,Q8NBM4,P21912,P31749,P52732 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 360,606,329,73,364,119,806,403,738,314,636,676 | 1310,1075,606,314,636,73,364,329,812,676,1219,1081,119,1161,738,403,360,806 | -0.11596206747168612,0.03925969392486323,0.49160405626708076,1.1001502232099265,0.4570917855835725,2.3276237027439657,0.9480828206502808,1.0550869617499012,0.2622351395530162,0.4048059034205665,-0.05710757719101301,0.03925969392486323,1.951920624080694,-0.01830586786658518,0.3341023914526849,0.8542183112675076,0.963531... | 2,701 |
Oxidoreductase activity acting on the ch ch group of donors | 11 | 28 | 2.053083 | 0.040065 | O15254,Q15067,Q15392,Q9UBM7,Q9BY49,Q9NZ01,Q14739,Q6NUM9,Q7KZN9,Q9H7Z7,P21912 | Functions | GO Molecular function | msigdb_gomf | 224,259,131,36,99,6,53,151,152,347,314 | 224,620,1495,2381,2546,314,1570,363,2397,1098,812,455,814,53,2565,259,131,151,1293,152,689,2686,2487,99,347,726,6,36 | 1.3891595529580087,0.47438206198749655,-0.23609532189713084,-0.8915779896099613,-1.183730197015092,1.1001502232099265,-0.27688196692354466,0.9480828206502808,-0.9151995911546438,0.02015513431309902,0.2622351395530162,0.742084510223003,0.2622351395530162,2.5574259051028014,-1.2089703136081216,1.2901855033977274,1.890133... | 2,701 |
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