term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metal ion transmembrane transporter activity
| 14
| 24
| 2.630373
| 0.008529
|
Q96QD8,Q8N4V1,Q9BXP2,P61619,Q9H2H9,Q9H0U3,Q9Y6M7,P98194,P05023,P16615,Q9UM00,O95202,Q9HD20,P07355
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
389,70,359,169,138,238,143,178,243,252,318,405,58,313
|
405,243,1118,313,2212,1044,252,1024,699,2574,169,178,70,598,1426,468,389,359,238,138,58,318,681,143
|
0.8383751777967641,1.332880448717388,0.000966854535827841,1.1001502232099265,-0.707024253971549,0.05828124665914992,1.3044639973832475,0.07722049678650203,0.36959730040846983,-1.234355168597917,1.6469125414193932,1.5805599528095038,2.3723562686361177,0.5087582951969946,-0.1756174312141384,0.7258267538427401,0.8857323527866384,0.9635315701724516,1.3470190066264098,1.8400575311170198,2.5038189105500694,1.1001502232099265,0.4048059034205665,1.802114682609706
| 2,701
|
Secondary active transmembrane transporter activity
| 16
| 22
| 2.625581
| 0.00865
|
Q96ES6,P41440,Q96QD8,P12236,Q9BXP2,Q9H2H9,O00400,P04920,Q9Y6M7,Q00325,Q9UBX3,Q8NE86,P51790,O95202,P53985,Q02978
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,321,389,415,359,138,170,462,143,551,47,598,280,405,254,183
|
170,405,462,605,1044,750,415,321,280,813,254,551,183,839,598,128,389,359,138,47,681,143
|
1.6337233768883894,0.8383751777967641,0.7258267538427401,0.49160405626708076,0.05828124665914992,0.31624613864460677,0.8224740869191085,1.085181098032962,1.203511402271728,0.2622351395530162,1.3044639973832475,0.5767080236830171,1.540253330753097,0.24408206050486364,0.5087582951969946,1.9025621688075542,0.8857323527866384,0.9635315701724516,1.8400575311170198,2.6626661752675664,0.4048059034205665,1.802114682609706
| 2,701
|
Inorganic molecular entity transmembrane transporter activity
| 40
| 75
| 2.608274
| 0.0091
|
P00403,Q96ES6,Q96QD8,Q9Y487,Q9H2H9,Q9Y6M7,P51790,Q7KZN9,O95202,P56385,P45880,Q9Y277,P61619,P10606,O00400,Q9UBX3,P98194,Q9UM00,Q9Y5K8,Q9HD20,Q99797,Q02978,O75964,P21796,P07355,Q8N4V1,P04920,P31930,Q96ER9,Q13423,P13073,Q93050,P33527,Q9C0H2,Q9BXP2,Q9H0U3,P05023,Q9UDW1,O15439,P16615
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
251,128,389,134,138,143,280,152,405,407,28,166,169,298,170,47,178,318,452,58,317,183,57,62,313,70,462,81,468,340,343,91,348,94,359,238,243,118,248,252
|
2227,170,248,536,2015,57,405,251,462,243,1118,605,1568,313,2212,1044,749,298,750,343,252,1024,1076,1343,1602,62,699,622,2337,81,348,1777,1882,2191,28,2573,2574,280,813,2306,407,471,169,178,551,183,340,518,1961,152,70,598,1836,1426,91,468,128,389,566,317,359,94,238,138,58,47,118,1433,318,166,681,134,452,2099,143
|
-0.7296754780456444,1.6337233768883894,1.3186955452496854,0.593531179510868,-0.5516452556198194,2.5038189105500694,0.8383751777967641,1.3044639973832475,0.7258267538427401,1.332880448717388,0.000966854535827841,0.49160405626708076,-0.27688196692354466,1.1001502232099265,-0.707024253971549,0.05828124665914992,0.31624613864460677,1.1447500131709183,0.31624613864460677,1.0095506891404633,1.3044639973832475,0.07722049678650203,0.03925969392486323,-0.1357571511500396,-0.2974182770678407,2.460444745964291,0.36959730040846983,0.47438206198749655,-0.8447106696636559,2.248201202031891,0.9942651268493035,-0.40156531384122846,-0.4652592172226013,-0.6844888552895658,2.905147117866422,-1.234355168597917,-1.234355168597917,1.203511402271728,0.2622351395530162,-0.7983359233670255,0.8383751777967641,0.7095080229146791,1.6469125414193932,1.5805599528095038,0.5767080236830171,1.540253330753097,1.0247826043693027,0.6269838228448695,-0.5082402040270202,1.7381246312443195,2.3723562686361177,0.5087582951969946,-0.4226942464977029,-0.1756174312141384,2.1672811097819484,0.7258267538427401,1.9025621688075542,0.8857323527866384,0.559819657694308,1.1001502232099265,0.9635315701724516,2.1321287594832308,1.3470190066264098,1.8400575311170198,2.5038189105500694,2.6626661752675664,1.9763891703113325,-0.1756174312141384,1.1001502232099265,1.6862398498357258,0.4048059034205665,1.8901336133115505,0.7582817372111945,-0.5954826549590951,1.802114682609706
| 2,701
|
Inner mitochondrial membrane organization
| 16
| 21
| 2.602183
| 0.009263
|
P17152,O60313,Q16891,Q9P0J0,Q13505,Q6UXV4,Q8WWC4,Q5XKP0,Q9Y5J7,Q9Y5J9,Q9Y512,O75431,Q9Y4W6,Q9BUR5,O95202,Q9H3K2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
320,189,388,133,296,200,140,273,276,209,212,309,469,186,405,223
|
189,309,684,405,320,2594,296,388,596,273,200,140,186,223,475,1335,133,469,212,276,209
|
1.5131717487404053,1.115067853889435,0.38723710682081225,0.8383751777967641,1.085181098032962,-1.3373751235719122,1.1595152238833708,0.8857323527866384,0.5087582951969946,1.2470652835370355,1.4859193366122214,1.8147994633249862,1.540253330753097,1.4031156606893533,0.7095080229146791,-0.11596206747168612,1.8901336133115505,0.7258267538427401,1.4447157506111374,1.2325959289574466,1.4722284064322555
| 2,701
|
Endoplasmic reticulum organization
| 20
| 38
| 2.59768
| 0.009386
|
Q8NHH9,Q00765,O95197,P50542,Q12981,O43681,P61619,Q15629,Q9P2W9,O00429,Q8N4V1,Q6P1A2,P49257,Q5J8M3,Q15363,P57088,Q96A33,Q9NXE4,Q9NQC3,Q9NP72
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
512,395,10,516,543,536,169,41,181,434,70,586,583,465,349,227,236,504,122,641
|
1277,434,1070,1374,1767,536,1489,1770,10,1117,1210,583,516,227,169,395,801,543,2145,349,41,465,1355,586,2691,70,660,1268,512,236,927,641,692,122,504,1197,1168,181
|
-0.09625596283480581,0.7744188751377666,0.03925969392486323,-0.1556420051329787,-0.40156531384122846,0.593531179510868,-0.23609532189713084,-0.40156531384122846,3.6262130177039786,0.000966854535827841,-0.05710757719101301,0.5258452995193653,0.6269838228448695,1.3891595529580087,1.6469125414193932,0.8700039001223019,0.28031310881637544,0.593531179510868,-0.6397609283995005,0.9942651268493035,2.745032234471493,0.7258267538427401,-0.1357571511500396,0.5258452995193653,-2.878787438217548,2.3723562686361177,0.42230424858015453,-0.07663805632366444,0.6436142777409396,1.3470190066264098,0.17070624531058928,0.4570917855835725,0.38723710682081225,1.93963397583531,0.6601814574178648,-0.03766376468274858,-0.01830586786658518,1.5537307142177417
| 2,701
|
SLC25 family of mitochondrial transporters
| 9
| 18
| 2.582479
| 0.009809
|
O43772,Q70HW3,Q9UBX3,Q9NZJ7,Q9BQT8,O43808,Q9H2D1,Q02978,Q9Y6C9
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
103,11,47,146,50,147,22,183,92
|
103,147,889,605,750,415,551,183,344,11,50,22,220,146,47,666,933,92
|
2.060949321084514,1.7638347606018192,0.18916598311737365,0.49160405626708076,0.31624613864460677,0.8224740869191085,0.5767080236830171,1.540253330753097,1.0095506891404633,3.617915206963102,2.578682101820039,3.1065707089213883,1.417026875112562,1.7766325496335293,2.6626661752675664,0.42230424858015453,0.17070624531058928,2.1555955949755234
| 2,701
|
Mitochondrial carrier domain superfamily [IPR023395]
| 9
| 18
| 2.582479
| 0.009809
|
O43772,Q70HW3,Q9UBX3,Q9NZJ7,Q9BQT8,O43808,Q9H2D1,Q02978,Q9Y6C9
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
103,11,47,146,50,147,22,183,92
|
103,147,889,605,750,415,551,183,344,11,50,22,220,146,47,666,933,92
|
2.060949321084514,1.7638347606018192,0.18916598311737365,0.49160405626708076,0.31624613864460677,0.8224740869191085,0.5767080236830171,1.540253330753097,1.0095506891404633,3.617915206963102,2.578682101820039,3.1065707089213883,1.417026875112562,1.7766325496335293,2.6626661752675664,0.42230424858015453,0.17070624531058928,2.1555955949755234
| 2,701
|
Mitochondrial substrate/solute carrier [IPR018108]
| 9
| 18
| 2.582479
| 0.009809
|
O43772,Q70HW3,Q9UBX3,Q9NZJ7,Q9BQT8,O43808,Q9H2D1,Q02978,Q9Y6C9
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
103,11,47,146,50,147,22,183,92
|
103,147,889,605,750,415,551,183,344,11,50,22,220,146,47,666,933,92
|
2.060949321084514,1.7638347606018192,0.18916598311737365,0.49160405626708076,0.31624613864460677,0.8224740869191085,0.5767080236830171,1.540253330753097,1.0095506891404633,3.617915206963102,2.578682101820039,3.1065707089213883,1.417026875112562,1.7766325496335293,2.6626661752675664,0.42230424858015453,0.17070624531058928,2.1555955949755234
| 2,701
|
er
| 50
| 77
| 2.575087
| 0.010021
|
Q8NHH9,P04843,O15173,Q15392,Q07065,Q8TCJ2,Q9Y487,O14735,Q00765,Q8N766,O95470,O75340,Q06136,Q969V3,Q9NR31,Q16850,P49755,Q12981,Q9Y5M8,P61019,O75915,P51153,P51151,Q86Y07,O00400,O95674,Q9NTJ5,P48651,Q14739,Q9P2W9,O00264,Q969Q5,Q9UM00,Q8NF37,P27824,Q8N4V1,O00767,Q5J8M3,P48449,O96005,Q15738,Q13190,Q15363,P46977,Q96A33,Q969M3,O75396,Q9NQC3,Q9NP72,P51572
|
Localization
|
OpenCell Localization
|
opencell_localization
|
512,635,127,131,263,648,134,642,395,660,144,272,18,274,275,278,277,543,158,541,537,675,164,556,170,172,694,175,53,181,308,311,318,184,570,70,335,465,83,85,594,215,349,229,236,376,619,122,641,253
|
308,170,335,642,127,1972,2071,1767,272,619,537,1117,144,172,85,1696,635,1023,2281,1150,1441,570,1078,229,83,175,277,164,675,253,2341,1638,2142,541,943,1125,395,18,263,543,215,53,2145,349,131,594,2086,278,465,1191,2088,556,70,660,184,512,648,2437,2090,376,311,274,236,927,1194,641,692,122,275,694,1197,1168,181,318,792,134,158
|
1.115067853889435,1.6337233768883894,1.0399612405003023,0.439732694154855,1.9025621688075542,-0.5298892096352652,-0.5954826549590951,-0.40156531384122846,1.2470652835370355,0.47438206198749655,0.593531179510868,0.000966854535827841,1.7893924505266094,1.6072235088664195,2.213707758412066,-0.3596097669606752,0.4570917855835725,0.07722049678650203,-0.7753301127313307,-0.01830586786658518,-0.19568424190462033,0.5428655840352268,0.03925969392486323,1.3611115149729005,2.2367341600459416,1.5939123156550052,1.2180780751359057,1.6862398498357258,0.4048059034205665,1.3044639973832475,-0.8447106696636559,-0.3180510829696362,-0.6397609283995005,0.593531179510868,0.15216824938562942,0.000966854535827841,0.8700039001223019,3.244826799017829,1.2758597586554565,0.593531179510868,1.4308934785310223,2.5574259051028014,-0.6397609283995005,0.9942651268493035,1.8901336133115505,0.5087582951969946,-0.5954826549590951,1.2180780751359057,0.7258267538427401,-0.03766376468274858,-0.5954826549590951,0.5767080236830171,2.3723562686361177,0.42230424858015453,1.540253330753097,0.6436142777409396,0.439732694154855,-0.9628253083803223,-0.5954826549590951,0.9325789136855012,1.115067853889435,1.2325959289574466,1.3470190066264098,0.17070624531058928,-0.03766376468274858,0.4570917855835725,0.38723710682081225,1.93963397583531,1.2325959289574466,0.38723710682081225,-0.03766376468274858,-0.01830586786658518,1.5537307142177417,1.1001502232099265,0.2983165752789475,1.8901336133115505,1.7122602692585014
| 2,701
|
Ion channel transport
| 11
| 27
| 2.557539
| 0.010542
|
Q93050,Q9Y487,P98194,P05023,Q15904,P16615,P51790,Q9Y5K8,Q9HD20,P61421,Q9C0H2
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
91,134,178,243,436,252,280,452,58,471,94
|
243,1118,252,1024,1343,1602,699,1283,1882,2191,280,813,624,471,178,1262,1506,436,518,1296,91,1757,94,58,1433,134,452
|
1.332880448717388,0.000966854535827841,1.3044639973832475,0.07722049678650203,-0.1357571511500396,-0.2974182770678407,0.36959730040846983,-0.09625596283480581,-0.4652592172226013,-0.6844888552895658,1.203511402271728,0.2622351395530162,0.47438206198749655,0.7095080229146791,1.5805599528095038,-0.07663805632366444,-0.23609532189713084,0.7744188751377666,0.6269838228448695,-0.09625596283480581,2.1672811097819484,-0.3805374686703146,2.1321287594832308,2.5038189105500694,-0.1756174312141384,1.8901336133115505,0.7582817372111945
| 2,701
|
Sphingolipid metabolism
| 6
| 10
| 2.553387
| 0.010668
|
P07602,P17900,Q9NZ01,O95470,Q06136,Q13510
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
31,163,6,144,18,119
|
1972,2071,144,177,31,163,18,119,1509,6
|
-0.5298892096352652,-0.5954826549590951,1.7893924505266094,1.5805599528095038,2.8458055936098234,1.6862398498357258,3.244826799017829,1.951920624080694,-0.23609532189713084,3.953135916812116
| 2,701
|
Copii coated er to golgi transport vesicle
| 16
| 29
| 2.539477
| 0.011102
|
Q9Y3A6,Q9BVK6,Q9Y3B3,P49257,O75340,Q5VYK3,O95487,Q9NR31,Q9Y282,P49755,P10321,Q13190,Q969M3,Q7Z7H5,Q15363,O95070
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
430,174,302,583,272,530,304,275,54,277,563,215,376,219,349,159
|
1374,1974,272,619,1770,159,1567,304,2105,563,583,277,1992,1009,801,215,349,2084,1161,530,219,376,174,275,1967,54,430,302,711
|
-0.1556420051329787,-0.5298892096352652,1.2470652835370355,0.47438206198749655,-0.40156531384122846,1.6992696820323683,-0.27688196692354466,1.1299343362894672,-0.6175661397525806,0.559819657694308,0.5258452995193653,1.2180780751359057,-0.5298892096352652,0.0960781397108018,0.28031310881637544,1.4308934785310223,0.9942651268493035,-0.5954826549590951,-0.01830586786658518,0.6102896170952945,1.417026875112562,0.9325789136855012,1.6072235088664195,1.2325959289574466,-0.5082402040270202,2.5574259051028014,0.8065146214158287,1.1447500131709183,0.36959730040846983
| 2,701
|
Cholesterol binding
| 6
| 12
| 2.530948
| 0.011375
|
O15118,P61916,Q14108,Q9H4L5,P45880,P21796
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
130,72,21,153,28,62
|
130,794,1817,2212,62,1440,195,28,72,21,1194,153
|
1.8901336133115505,0.28031310881637544,-0.4226942464977029,-0.707024253971549,2.460444745964291,-0.19568424190462033,1.4995670283946096,2.905147117866422,2.36121680514361,3.1159288248830843,-0.03766376468274858,1.7381246312443195
| 2,701
|
Active transmembrane transporter activity
| 39
| 72
| 2.530059
| 0.011404
|
P00403,Q96ES6,O43676,Q9P0J0,Q96QD8,Q9H2H9,Q16718,Q9Y6M7,P51790,Q7KZN9,O95202,Q9Y6M9,O96000,P12236,O95169,P10606,O00400,Q9UBX3,P98194,P08183,Q02978,Q9Y5K8,Q9HD20,P41440,O95168,P04920,P31930,P13073,P61421,P33527,P28288,O75306,Q9BXP2,P05023,Q9UDW1,O75027,O15439,P53985,P16615
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
251,128,4,133,389,138,399,143,280,152,405,30,290,415,295,298,170,47,178,180,183,452,58,321,325,462,81,343,471,348,470,478,359,243,118,371,248,254,252
|
2556,170,1115,248,4,1973,371,2516,478,1528,2230,325,295,2442,405,2017,290,251,462,243,1118,605,1568,180,1044,749,298,750,415,343,252,2561,1024,1076,1343,1602,699,470,2046,81,348,1882,2191,321,2608,280,813,1256,254,471,178,551,183,498,839,399,609,152,598,128,389,359,138,58,133,47,118,1433,681,452,143,30
|
-1.2089703136081216,1.6337233768883894,0.000966854535827841,1.3186955452496854,4.14073910845815,-0.5298892096352652,0.9325789136855012,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,0.8383751777967641,-0.5516452556198194,1.1742303044100273,1.3044639973832475,0.7258267538427401,1.332880448717388,0.000966854535827841,0.49160405626708076,-0.27688196692354466,1.5537307142177417,0.05828124665914992,0.31624613864460677,1.1447500131709183,0.31624613864460677,0.8224740869191085,1.0095506891404633,1.3044639973832475,-1.2089703136081216,0.07722049678650203,0.03925969392486323,-0.1357571511500396,-0.2974182770678407,0.36959730040846983,0.7095080229146791,-0.5735093847387928,2.248201202031891,0.9942651268493035,-0.4652592172226013,-0.6844888552895658,1.085181098032962,-1.3635087831226131,1.203511402271728,0.2622351395530162,-0.07663805632366444,1.3044639973832475,0.7095080229146791,1.5805599528095038,0.5767080236830171,1.540253330753097,0.6601814574178648,0.24408206050486364,0.8542183112675076,0.49160405626708076,1.7381246312443195,0.5087582951969946,1.9025621688075542,0.8857323527866384,0.9635315701724516,1.8400575311170198,2.5038189105500694,1.8901336133115505,2.6626661752675664,1.9763891703113325,-0.1756174312141384,0.4048059034205665,0.7582817372111945,1.802114682609706,2.8557533308424374
| 2,701
|
Intermediate filament cytoskeleton
| 10
| 31
| 2.509318
| 0.012096
|
P58107,Q15149,P15924,Q16352,P14923,O75832,Q3SXM5,P02545,P48729,P08670
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
101,198,14,78,16,303,19,214,380,286
|
1811,303,214,1494,1379,286,16,14,2215,941,380,1475,2496,101,2645,1538,2307,198,78,2086,19,840,649,628,1368,857,821,1234,451,930,1849
|
-0.4226942464977029,1.1299343362894672,1.4308934785310223,-0.23609532189713084,-0.1556420051329787,1.1888955874119858,3.2538860606266975,3.3434324737059566,-0.707024253971549,0.15216824938562942,0.9170194617840494,-0.21584326062426626,-1.0841853199459772,2.072894727430521,-1.6616232828965283,-0.25644127155135765,-0.7983359233670255,1.4859193366122214,2.2710437709642273,-0.5954826549590951,3.235748197482853,0.24408206050486364,0.439732694154855,0.47438206198749655,-0.1357571511500396,0.22585325728994807,0.2622351395530162,-0.05710757719101301,0.7582817372111945,0.17070624531058928,-0.4226942464977029
| 2,701
|
Sterol metabolic process
| 14
| 32
| 2.509248
| 0.012099
|
O15118,Q15392,Q9UBM7,Q8WTV0,P16435,Q14534,P37268,P61916,Q9BQE5,P04062,P48449,Q14739,Q16850,Q15800
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,131,36,322,441,327,69,72,12,177,83,53,278,409
|
130,794,620,1817,1696,177,1819,940,441,2216,69,2509,2385,83,455,1991,72,2266,2418,2471,327,53,2220,131,594,409,278,586,322,12,36,2475
|
1.8901336133115505,0.28031310881637544,0.47438206198749655,-0.4226942464977029,-0.3596097669606752,1.5805599528095038,-0.4226942464977029,0.15216824938562942,0.7582817372111945,-0.707024253971549,2.3945487262934133,-1.1088623151263601,-0.8915779896099613,2.2367341600459416,0.742084510223003,-0.5298892096352652,2.36121680514361,-0.7524437006538256,-0.9389482483908096,-1.035240699093695,1.0701601286370668,2.5574259051028014,-0.707024253971549,1.8901336133115505,0.5087582951969946,0.8383751777967641,1.2180780751359057,0.5258452995193653,1.085181098032962,3.5509413806281707,2.8057811853844417,-1.035240699093695
| 2,701
|
Lipid transporter activity
| 11
| 19
| 2.495945
| 0.012562
|
O15118,P17900,P30536,P61916,Q01469,P08183,P33527,O15439,Q9H4L5,P28288,P11166
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
130,163,195,72,51,180,348,248,153,470,222
|
130,248,180,222,163,797,470,195,348,1050,72,51,518,1191,1296,610,1688,1194,153
|
1.8901336133115505,1.3186955452496854,1.5537307142177417,1.4031156606893533,1.6862398498357258,0.28031310881637544,0.7095080229146791,1.4995670283946096,0.9942651268493035,0.05828124665914992,2.36121680514361,2.568067202131094,0.6269838228448695,-0.03766376468274858,-0.09625596283480581,0.49160405626708076,-0.33878127776425015,-0.03766376468274858,1.7381246312443195
| 2,701
|
Mitochondrial transmembrane transport
| 27
| 46
| 2.468859
| 0.013554
|
Q99595,Q9BVV7,Q8WWC4,Q9H2D1,O95202,P56385,P12236,Q3ZCQ8,O95831,Q00325,Q96NB2,Q9BQT8,O95563,O75964,P23786,P21796,O96008,O14925,Q8NE86,Q96ER9,Q9Y4W6,O75027,P05141,O43772,Q9H9B4,Q15388,Q6P4A7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,390,140,22,405,407,415,417,297,551,176,50,435,57,182,62,326,196,598,468,469,371,605,103,630,498,120
|
196,712,103,371,1493,889,2015,57,684,405,435,297,326,605,1568,2654,750,415,62,182,622,2337,1777,2573,2306,407,551,498,417,120,598,2367,140,468,176,3,906,50,390,22,630,2178,666,766,469,933
|
1.4859193366122214,0.351885919191322,2.060949321084514,0.9325789136855012,-0.23609532189713084,0.18916598311737365,-0.5516452556198194,2.5038189105500694,0.38723710682081225,0.8383751777967641,0.7744188751377666,1.1447500131709183,1.0701601286370668,0.49160405626708076,-0.27688196692354466,-1.746524104659968,0.31624613864460677,0.8224740869191085,2.460444745964291,1.540253330753097,0.47438206198749655,-0.8447106696636559,-0.40156531384122846,-1.234355168597917,-0.7983359233670255,0.8383751777967641,0.5767080236830171,0.6601814574178648,0.8224740869191085,1.951920624080694,0.5087582951969946,-0.8680821176442824,1.8147994633249862,0.7258267538427401,1.5939123156550052,4.492615277702867,0.18916598311737365,2.578682101820039,0.8857323527866384,3.1065707089213883,0.47438206198749655,-0.6620681262993946,0.42230424858015453,0.31624613864460677,0.7258267538427401,0.17070624531058928
| 2,701
|
transporter
| 16
| 56
| 2.46844
| 0.01357
|
P41440,Q99595,Q8NFH4,O43772,P61619,Q99805,Q9HD45,Q8TEX9,Q9H2V7,Q9NR77,Q9H2D1,Q567V2,Q15070,O15397,P52292,P53985
|
Functions
|
Panther Protein class
|
panther_protein_class
|
321,3,249,103,169,202,42,269,246,113,22,86,56,240,26,254
|
1173,845,1434,1524,1626,240,712,536,103,2355,1001,795,1604,2050,321,1050,1887,26,1389,2112,254,623,834,1009,835,169,487,1508,56,86,1961,1897,647,249,1898,269,467,1087,1869,600,1459,3,202,338,2501,725,22,246,708,42,113,548,1199,766,997,933
|
-0.03766376468274858,0.22585325728994807,-0.19568424190462033,-0.25644127155135765,-0.3180510829696362,1.332880448717388,0.351885919191322,0.593531179510868,2.060949321084514,-0.8680821176442824,0.0960781397108018,0.28031310881637544,-0.2974182770678407,-0.5735093847387928,1.085181098032962,0.05828124665914992,-0.4652592172226013,2.9345111964169397,-0.1556420051329787,-0.6175661397525806,1.3044639973832475,0.47438206198749655,0.24408206050486364,0.0960781397108018,0.24408206050486364,1.6469125414193932,0.676685832241666,-0.23609532189713084,2.5360636019540204,2.2021480739281882,-0.5082402040270202,-0.4652592172226013,0.439732694154855,1.3186955452496854,-0.4652592172226013,1.2614864555637981,0.7258267538427401,0.03925969392486323,-0.4439252239854569,0.5087582951969946,-0.19568424190462033,4.492615277702867,1.4859193366122214,1.0399612405003023,-1.0841853199459772,0.351885919191322,3.1065707089213883,1.332880448717388,0.36959730040846983,2.745032234471493,2.024912659220012,0.593531179510868,-0.03766376468274858,0.31624613864460677,0.11485486211702632,0.17070624531058928
| 2,701
|
Primary active transmembrane transporter activity
| 25
| 51
| 2.466112
| 0.013659
|
P00403,O43676,Q9P0J0,Q16718,Q7KZN9,Q9Y6M9,O96000,O95169,P10606,P98194,P08183,Q9Y5K8,Q9HD20,O95168,P31930,P13073,P61421,P28288,P33527,O75306,P05023,Q9UDW1,O75027,O15439,P16615
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
251,4,133,399,152,30,290,295,298,178,180,452,58,325,81,343,471,470,348,478,243,118,371,248,252
|
2556,1115,248,4,1973,371,2516,478,1528,2230,325,295,2442,2017,290,251,243,1118,1568,180,749,298,343,252,2561,1024,1076,1343,1602,699,470,2046,81,348,1882,2191,2608,813,1256,471,178,498,399,609,152,58,133,118,1433,452,30
|
-1.2089703136081216,0.000966854535827841,1.3186955452496854,4.14073910845815,-0.5298892096352652,0.9325789136855012,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,1.1742303044100273,1.3044639973832475,1.332880448717388,0.000966854535827841,-0.27688196692354466,1.5537307142177417,0.31624613864460677,1.1447500131709183,1.0095506891404633,1.3044639973832475,-1.2089703136081216,0.07722049678650203,0.03925969392486323,-0.1357571511500396,-0.2974182770678407,0.36959730040846983,0.7095080229146791,-0.5735093847387928,2.248201202031891,0.9942651268493035,-0.4652592172226013,-0.6844888552895658,-1.3635087831226131,0.2622351395530162,-0.07663805632366444,0.7095080229146791,1.5805599528095038,0.6601814574178648,0.8542183112675076,0.49160405626708076,1.7381246312443195,2.5038189105500694,1.8901336133115505,1.9763891703113325,-0.1756174312141384,0.7582817372111945,2.8557533308424374
| 2,701
|
Sulfur compound transmembrane transporter activity
| 7
| 9
| 2.438835
| 0.014735
|
Q8TB61,Q70HW3,O00400,Q9UBX3,O15439,Q9HC21,Q02978
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
136,11,170,47,248,220,183
|
170,248,348,183,11,136,220,47,681
|
1.6337233768883894,1.3186955452496854,0.9942651268493035,1.540253330753097,3.617915206963102,1.8526312438376766,1.417026875112562,2.6626661752675664,0.4048059034205665
| 2,701
|
Membrane lipid biosynthetic process
| 8
| 17
| 2.437475
| 0.01479
|
Q99805,Q96G23,Q9P035,P04062,Q06136,O95470,Q13510,Q8NBX0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
202,27,208,177,18,144,119,59
|
1972,2071,144,177,797,18,119,1509,596,59,287,27,1300,202,504,208,1168
|
-0.5298892096352652,-0.5954826549590951,1.7893924505266094,1.5805599528095038,0.28031310881637544,3.244826799017829,1.951920624080694,-0.23609532189713084,0.5087582951969946,2.48218674176581,1.1888955874119858,2.92474561480173,-0.09625596283480581,1.4859193366122214,0.6601814574178648,1.4722284064322555,-0.01830586786658518
| 2,701
|
Sterol binding
| 6
| 15
| 2.435478
| 0.014872
|
O15118,P61916,Q14108,Q9H4L5,P45880,P21796
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
130,72,21,153,28,62
|
130,794,1817,2212,62,797,1440,195,28,72,21,610,1688,1194,153
|
1.8901336133115505,0.28031310881637544,-0.4226942464977029,-0.707024253971549,2.460444745964291,0.28031310881637544,-0.19568424190462033,1.4995670283946096,2.905147117866422,2.36121680514361,3.1159288248830843,0.49160405626708076,-0.33878127776425015,-0.03766376468274858,1.7381246312443195
| 2,701
|
Alcohol binding
| 6
| 14
| 2.434278
| 0.014922
|
O15118,P61916,Q14108,Q9H4L5,P45880,P21796
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
130,72,21,153,28,62
|
642,130,794,1817,2212,62,1440,1820,195,28,72,21,1194,153
|
0.439732694154855,1.8901336133115505,0.28031310881637544,-0.4226942464977029,-0.707024253971549,2.460444745964291,-0.19568424190462033,-0.4226942464977029,1.4995670283946096,2.905147117866422,2.36121680514361,3.1159288248830843,-0.03766376468274858,1.7381246312443195
| 2,701
|
secondary carrier transporter
| 10
| 15
| 2.41934
| 0.015549
|
Q96ES6,Q9BXP2,Q8TB61,O00400,Q9Y6M7,Q9UBX3,Q6NT16,Q9BQT8,Q02978,O95202
|
Functions
|
Panther Protein class
|
panther_protein_class
|
128,359,136,170,143,47,49,50,183,405
|
170,889,405,462,183,49,1191,136,128,50,359,47,666,681,143
|
1.6337233768883894,0.18916598311737365,0.8383751777967641,0.7258267538427401,1.540253330753097,2.5892707322696364,-0.03766376468274858,1.8526312438376766,1.9025621688075542,2.578682101820039,0.9635315701724516,2.6626661752675664,0.42230424858015453,0.4048059034205665,1.802114682609706
| 2,701
|
Vitamin transport
| 7
| 9
| 2.417434
| 0.01563
|
P41440,Q8WTV0,P04062,P38435,Q9H2D1,Q9HC21,P11166
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
321,322,177,114,22,220,222
|
177,222,348,114,321,322,22,220,681
|
1.5805599528095038,1.4031156606893533,0.9942651268493035,2.0128330114691035,1.085181098032962,1.085181098032962,3.1065707089213883,1.417026875112562,0.4048059034205665
| 2,701
|
Exopeptidase activity
| 11
| 28
| 2.407125
| 0.016079
|
P09960,P10619,O75844,Q9UIQ6,P42785,P55786,Q13867,Q969V3,Q9HB40,Q9H3G5,O14773
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
226,168,43,142,109,17,145,274,256,288,319
|
319,43,1470,808,226,168,2642,2508,1703,1098,109,17,2611,145,880,466,843,274,2091,2326,288,1369,256,1331,1370,1040,360,142
|
1.085181098032962,2.734822878575379,-0.21584326062426626,0.2622351395530162,1.3891595529580087,1.6469125414193932,-1.6336795739285952,-1.1088623151263601,-0.3596097669606752,0.02015513431309902,2.0489706294219476,3.244826799017829,-1.3897974292022441,1.7766325496335293,0.20754810800791113,0.7258267538427401,0.24408206050486364,1.2325959289574466,-0.5954826549590951,-0.8214623601730139,1.1888955874119858,-0.1357571511500396,1.3044639973832475,-0.11596206747168612,-0.1357571511500396,0.07722049678650203,0.9635315701724516,1.8147994633249862
| 2,701
|
Nonalcoholic fatty liver disease
| 15
| 44
| 2.401688
| 0.01632
|
P00403,P14406,O96000,O14949,O43676,Q9P0J0,Q16611,O95169,O95168,Q86Y39,P10606,P31930,Q9UDW1,P21912,Q9Y6M9
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
251,1,290,65,4,133,37,295,325,104,298,81,118,314,30
|
2556,1115,65,4,1973,2516,478,1528,2230,325,295,2442,2017,290,251,1042,749,1950,298,343,1,1471,2561,1076,314,569,2046,2397,636,81,812,2608,1256,643,1448,1929,2267,37,399,609,104,133,118,30
|
-1.2089703136081216,0.000966854535827841,2.4276234185896435,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,1.1742303044100273,1.3044639973832475,0.05828124665914992,0.31624613864460677,-0.5082402040270202,1.1447500131709183,1.0095506891404633,5.210648084460358,-0.21584326062426626,-1.2089703136081216,0.03925969392486323,1.1001502232099265,0.5428655840352268,-0.5735093847387928,-0.9151995911546438,0.4570917855835725,2.248201202031891,0.2622351395530162,-1.3635087831226131,-0.07663805632366444,0.439732694154855,-0.19568424190462033,-0.4866972109565579,-0.7524437006538256,2.775514718206515,0.8542183112675076,0.49160405626708076,2.060949321084514,1.8901336133115505,1.9763891703113325,2.8557533308424374
| 2,701
|
MFS transporter superfamily [IPR036259]
| 7
| 9
| 2.399436
| 0.01642
|
P41440,Q96ES6,O00400,Q9H2V7,Q6NT16,P53985,P11166
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
321,128,170,246,49,254,222
|
170,222,321,254,1961,49,128,338,246
|
1.6337233768883894,1.4031156606893533,1.085181098032962,1.3044639973832475,-0.5082402040270202,2.5892707322696364,1.9025621688075542,1.0399612405003023,1.332880448717388
| 2,701
|
Lipid localization
| 26
| 64
| 2.396271
| 0.016563
|
O15118,Q9BQE5,Q9NZJ7,O43808,Q14108,Q9H4L5,O15260,P07602,P17900,O95674,P04062,Q01469,P08183,Q9BUR5,P23786,P07355,Q8WTV0,P30536,Q14534,P61916,P33527,P11166,Q9H6V9,O43772,Q9H2V7,O15439
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,12,146,147,21,153,285,31,163,172,177,51,180,186,182,313,322,195,327,72,348,222,96,103,246,248
|
1277,2698,130,285,248,103,147,1377,1567,1437,172,2583,177,890,313,31,829,1633,180,222,716,163,797,1440,182,470,1820,195,636,1248,348,365,1050,72,2266,51,1081,21,327,518,446,586,1191,721,1296,2579,322,610,501,12,927,186,1688,1194,1366,246,153,96,146,1168,2475,766,1909,710
|
-0.09625596283480581,-4.819863517888487,1.8901336133115505,1.1888955874119858,1.3186955452496854,2.060949321084514,1.7638347606018192,-0.1556420051329787,-0.27688196692354466,-0.19568424190462033,1.6072235088664195,-1.3113946688909883,1.5805599528095038,0.18916598311737365,1.1001502232099265,2.8458055936098234,0.24408206050486364,-0.3180510829696362,1.5537307142177417,1.4031156606893533,0.351885919191322,1.6862398498357258,0.28031310881637544,-0.19568424190462033,1.540253330753097,0.7095080229146791,-0.4226942464977029,1.4995670283946096,0.4570917855835725,-0.07663805632366444,0.9942651268493035,0.9480828206502808,0.05828124665914992,2.36121680514361,-0.7524437006538256,2.568067202131094,0.03925969392486323,3.1159288248830843,1.0701601286370668,0.6269838228448695,0.7582817372111945,0.5258452995193653,-0.03766376468274858,0.351885919191322,-0.09625596283480581,-1.2598863985527875,1.085181098032962,0.49160405626708076,0.6601814574178648,3.5509413806281707,0.17070624531058928,1.540253330753097,-0.33878127776425015,-0.03766376468274858,-0.1357571511500396,1.332880448717388,1.7381246312443195,2.1203470954716264,1.7766325496335293,-0.01830586786658518,-1.035240699093695,0.31624613864460677,-0.4652592172226013,0.36959730040846983
| 2,701
|
Sensory perception
| 10
| 30
| 2.395379
| 0.016603
|
O60313,P50897,Q9Y5J9,Q9Y5J7,Q01469,O60443,Q14108,Q9UM54,Q13432,Q9Y6M9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
189,74,209,276,51,241,21,157,255,30
|
423,189,241,2209,2558,1629,891,829,699,1880,1822,2358,74,2234,2116,51,2481,255,21,584,1356,1755,1659,1934,317,2037,157,276,209,30
|
0.8065146214158287,1.5131717487404053,1.332880448717388,-0.707024253971549,-1.2089703136081216,-0.3180510829696362,0.18916598311737365,0.24408206050486364,0.36959730040846983,-0.4652592172226013,-0.4226942464977029,-0.8680821176442824,2.3163672654572762,-0.7296754780456444,-0.6175661397525806,2.568067202131094,-1.0596452754232697,1.3044639973832475,3.1159288248830843,0.5258452995193653,-0.1357571511500396,-0.3805374686703146,-0.3180510829696362,-0.4866972109565579,1.1001502232099265,-0.5516452556198194,1.7122602692585014,1.2325959289574466,1.4722284064322555,2.8557533308424374
| 2,701
|
Tetrapyrrole binding
| 8
| 15
| 2.393505
| 0.016688
|
O15173,O43169,P30519,Q6UW02,Q96EY8,O00264,Q16850,Q7KZN9
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
127,0,66,165,79,308,278,152
|
308,127,0,749,672,581,66,278,165,152,900,79,1362,347,1941
|
1.115067853889435,1.9025621688075542,5.210648084460358,0.31624613864460677,0.4048059034205665,0.5258452995193653,2.416626861835804,1.2180780751359057,1.6862398498357258,1.7381246312443195,0.18916598311737365,2.2710437709642273,-0.1357571511500396,1.0095506891404633,-0.4866972109565579
| 2,701
|
Protein transporter activity
| 11
| 13
| 2.383936
| 0.017129
|
Q9NS69,Q99595,O96008,P61619,O14925,Q9Y5J9,Q8NBU5,Q15388,P49755,Q9HD20,Q07820
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
2,3,326,169,196,209,402,498,277,58,510
|
196,684,326,277,169,510,498,402,3,58,2,515,209
|
1.4859193366122214,0.38723710682081225,1.0701601286370668,1.2180780751359057,1.6469125414193932,0.6436142777409396,0.6601814574178648,0.8542183112675076,4.492615277702867,2.5038189105500694,5.159139452386764,0.6436142777409396,1.4722284064322555
| 2,701
|
Vascular transport
| 9
| 15
| 2.383532
| 0.017147
|
P41440,Q9H2H9,Q99808,Q01469,P08183,O15439,P53985,P33527,P11166
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
321,138,338,51,180,248,254,348,222
|
248,808,180,222,699,348,321,254,51,839,1191,389,338,138,681
|
1.3186955452496854,0.2622351395530162,1.5537307142177417,1.4031156606893533,0.36959730040846983,0.9942651268493035,1.085181098032962,1.3044639973832475,2.568067202131094,0.24408206050486364,-0.03766376468274858,0.8857323527866384,1.0399612405003023,1.8400575311170198,0.4048059034205665
| 2,701
|
Ion transport
| 24
| 53
| 2.373016
| 0.017643
|
Q96QD8,Q9Y487,Q9H2H9,Q9Y6M7,P51790,O95202,P56385,P45880,Q9Y277,P98194,Q15904,Q9UM00,Q9Y5K8,O75964,Q9H0H5,P21796,O96008,P04920,Q96ER9,Q93050,Q9C0H2,Q8NEW0,P05023,P16615
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
389,134,138,143,280,405,407,28,166,178,436,318,452,57,450,62,326,462,468,91,94,95,243,252
|
2227,2015,57,405,326,462,243,1118,1568,252,1024,1343,1602,62,699,622,2337,1777,1882,2191,28,2573,280,813,624,2306,407,471,178,2198,436,518,1961,1267,598,95,1836,91,468,389,566,906,94,450,138,1433,318,166,681,134,452,2099,143
|
-0.7296754780456444,-0.5516452556198194,2.5038189105500694,0.8383751777967641,1.0701601286370668,0.7258267538427401,1.332880448717388,0.000966854535827841,-0.27688196692354466,1.3044639973832475,0.07722049678650203,-0.1357571511500396,-0.2974182770678407,2.460444745964291,0.36959730040846983,0.47438206198749655,-0.8447106696636559,-0.40156531384122846,-0.4652592172226013,-0.6844888552895658,2.905147117866422,-1.234355168597917,1.203511402271728,0.2622351395530162,0.47438206198749655,-0.7983359233670255,0.8383751777967641,0.7095080229146791,1.5805599528095038,-0.6844888552895658,0.7744188751377666,0.6269838228448695,-0.5082402040270202,-0.07663805632366444,0.5087582951969946,2.1203470954716264,-0.4226942464977029,2.1672811097819484,0.7258267538427401,0.8857323527866384,0.559819657694308,0.18916598311737365,2.1321287594832308,0.7582817372111945,1.8400575311170198,-0.1756174312141384,1.1001502232099265,1.6862398498357258,0.4048059034205665,1.8901336133115505,0.7582817372111945,-0.5954826549590951,1.802114682609706
| 2,701
|
Rac2 gtpase cycle
| 15
| 32
| 2.369237
| 0.017825
|
O15173,Q13505,Q86Y07,P50402,Q86XL3,P49257,Q14185,P51149,Q9Y512,Q14739,Q7L576,P42167,Q9H0H5,Q9Y2U8,Q6IAA8
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
127,296,556,197,187,583,719,774,212,53,704,379,450,806,446
|
127,1117,808,1043,980,1923,379,985,583,197,774,1446,1448,2236,989,296,1159,719,53,1057,1291,446,704,187,556,927,450,2095,1065,1201,806,212
|
1.9025621688075542,0.000966854535827841,0.2622351395530162,0.05828124665914992,0.11485486211702632,-0.4866972109565579,0.9170194617840494,0.11485486211702632,0.5258452995193653,1.4859193366122214,0.2983165752789475,-0.19568424190462033,-0.19568424190462033,-0.7296754780456444,0.11485486211702632,1.1595152238833708,-0.01830586786658518,0.351885919191322,2.5574259051028014,0.05828124665914992,-0.09625596283480581,0.7582817372111945,0.36959730040846983,1.526733762162025,0.5767080236830171,0.17070624531058928,0.7582817372111945,-0.5954826549590951,0.05828124665914992,-0.03766376468274858,0.28031310881637544,1.4447157506111374
| 2,701
|
Vitamin transmembrane transporter activity
| 6
| 8
| 2.362967
| 0.018129
|
P41440,P04062,P38435,Q9H2D1,Q9HC21,P11166
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
321,177,114,22,220,222
|
177,222,348,114,321,22,220,681
|
1.5805599528095038,1.4031156606893533,0.9942651268493035,2.0128330114691035,1.085181098032962,3.1065707089213883,1.417026875112562,0.4048059034205665
| 2,701
|
Electron transport
| 15
| 42
| 2.352101
| 0.018668
|
O43169,P00403,O96000,O14949,O43676,Q9P0J0,O95169,Q6DKK2,Q86Y39,Q9H1E5,P31930,Q9UDW1,P21912,Q9H3N1,Q9Y6M9
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
0,251,290,65,4,133,295,102,104,111,81,118,314,29,30
|
2556,1115,65,0,1146,4,1973,2516,478,1528,2230,325,295,2442,2017,479,290,251,749,2457,2561,314,2216,569,2046,2397,81,2617,2608,1256,608,399,609,2576,102,104,1136,111,29,133,118,30
|
-1.2089703136081216,0.000966854535827841,2.4276234185896435,5.210648084460358,-0.01830586786658518,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,0.6931278673873417,1.1742303044100273,1.3044639973832475,0.31624613864460677,-1.0109701322777465,-1.2089703136081216,1.1001502232099265,-0.707024253971549,0.5428655840352268,-0.5735093847387928,-0.9151995911546438,2.248201202031891,-1.4428469635557346,-1.3635087831226131,-0.07663805632366444,0.49160405626708076,0.8542183112675076,0.49160405626708076,-1.234355168597917,2.072894727430521,2.060949321084514,0.000966854535827841,2.0489706294219476,2.8755795118567367,1.8901336133115505,1.9763891703113325,2.8557533308424374
| 2,701
|
Skin development
| 7
| 36
| 2.344813
| 0.019037
|
Q15392,P35222,O75844,P15924,P14923,P04062,Q13510
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,73,43,14,16,177,119
|
696,1342,2253,43,177,890,980,16,14,1918,981,621,2383,73,2574,1993,1859,2168,1451,2287,119,1575,1718,198,1014,131,499,594,946,1191,1683,2421,1622,1431,932,2099
|
0.36959730040846983,-0.1357571511500396,-0.7524437006538256,2.734822878575379,1.5805599528095038,0.18916598311737365,0.11485486211702632,3.2538860606266975,3.3434324737059566,-0.4866972109565579,0.11485486211702632,0.47438206198749655,-0.8915779896099613,2.3276237027439657,-1.234355168597917,-0.5298892096352652,-0.4439252239854569,-0.6620681262993946,-0.19568424190462033,-0.7753301127313307,1.951920624080694,-0.27688196692354466,-0.3596097669606752,1.4859193366122214,0.0960781397108018,1.8901336133115505,0.6601814574178648,0.5087582951969946,0.15216824938562942,-0.03766376468274858,-0.33878127776425015,-0.9389482483908096,-0.2974182770678407,-0.1756174312141384,0.17070624531058928,-0.5954826549590951
| 2,701
|
Cytochrome complex
| 7
| 15
| 2.34323
| 0.019118
|
P00403,O14949,P14406,P10606,P31930,Q9UDW1,Q7KZN9
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
251,65,1,298,81,118,152
|
1115,65,251,749,1950,298,343,1,1471,1076,569,81,152,118,617
|
0.000966854535827841,2.4276234185896435,1.3044639973832475,0.31624613864460677,-0.5082402040270202,1.1447500131709183,1.0095506891404633,5.210648084460358,-0.21584326062426626,0.03925969392486323,0.5428655840352268,2.248201202031891,1.7381246312443195,1.9763891703113325,0.49160405626708076
| 2,701
|
Nucleotide transport
| 10
| 14
| 2.342224
| 0.019169
|
O15439,Q08722,P41440,Q8TB61,O00400,Q99808,O43808,Q9H2D1,Q6NUK1,Q9HC21
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
248,354,321,136,170,338,147,22,344,220
|
170,248,147,605,750,415,321,354,344,136,1836,338,22,220
|
1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,0.9789255457318856,1.0095506891404633,1.8526312438376766,-0.4226942464977029,1.0399612405003023,3.1065707089213883,1.417026875112562
| 2,701
|
Exocytic vesicle
| 15
| 31
| 2.341394
| 0.019212
|
P09497,P51153,O00429,P50897,Q12846,Q9BVK6,Q15907,P11279,Q92542,Q14141,O43760,O15400,P51790,Q9BT78,P61421
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
698,675,434,74,529,174,266,80,599,375,52,561,280,346,471
|
434,1145,561,52,2188,698,80,1024,1671,1496,2574,74,774,675,280,1350,1639,471,529,838,375,1650,1616,1129,266,721,599,1796,346,174,1059
|
0.7744188751377666,-0.01830586786658518,0.559819657694308,2.5574259051028014,-0.6844888552895658,0.36959730040846983,2.248201202031891,0.07722049678650203,-0.33878127776425015,-0.23609532189713084,-1.234355168597917,2.3163672654572762,0.2983165752789475,0.4048059034205665,1.203511402271728,-0.1357571511500396,-0.3180510829696362,0.7095080229146791,0.6102896170952945,0.24408206050486364,0.9325789136855012,-0.3180510829696362,-0.2974182770678407,0.000966854535827841,1.2614864555637981,0.351885919191322,0.5087582951969946,-0.40156531384122846,1.0095506891404633,1.6072235088664195,0.05828124665914992
| 2,701
|
Respiratory chain
| 11
| 29
| 2.337427
| 0.019417
|
P00403,O14949,O96000,O43676,Q9P0J0,O95169,Q6DKK2,Q86Y39,P31930,Q9UDW1,Q9Y6M9
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
251,65,290,4,133,295,102,104,81,118,30
|
2556,1115,65,4,1973,2516,478,1528,2230,325,295,2442,2017,290,251,749,2561,569,2046,81,2608,1256,399,609,102,104,133,118,30
|
-1.2089703136081216,0.000966854535827841,2.4276234185896435,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,1.1742303044100273,1.3044639973832475,0.31624613864460677,-1.2089703136081216,0.5428655840352268,-0.5735093847387928,2.248201202031891,-1.3635087831226131,-0.07663805632366444,0.8542183112675076,0.49160405626708076,2.072894727430521,2.060949321084514,1.8901336133115505,1.9763891703113325,2.8557533308424374
| 2,701
|
Nucleotide transmembrane transporter activity
| 9
| 12
| 2.336006
| 0.019491
|
O15439,P41440,Q8TB61,O00400,Q99808,O43808,Q9H2D1,Q6NUK1,Q9HC21
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
248,321,136,170,338,147,22,344,220
|
170,248,147,605,750,415,321,344,136,338,22,220
|
1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,1.0095506891404633,1.8526312438376766,1.0399612405003023,3.1065707089213883,1.417026875112562
| 2,701
|
Organophosphate ester transmembrane transporter activity
| 9
| 12
| 2.336006
| 0.019491
|
O15439,P41440,Q8TB61,O00400,Q99808,O43808,Q9H2D1,Q6NUK1,Q9HC21
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
248,321,136,170,338,147,22,344,220
|
170,248,147,605,750,415,321,344,136,338,22,220
|
1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,1.0095506891404633,1.8526312438376766,1.0399612405003023,3.1065707089213883,1.417026875112562
| 2,701
|
Abnormal epidermal morphology
| 7
| 16
| 2.316609
| 0.020525
|
O75844,Q14574,P15924,P14923,Q06136,P98194,P02545
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
43,13,14,16,18,178,214
|
2456,43,1947,214,16,14,252,2605,636,1187,676,178,18,13,1191,1239
|
-1.0109701322777465,2.734822878575379,-0.5082402040270202,1.4308934785310223,3.2538860606266975,3.3434324737059566,1.3044639973832475,-1.3635087831226131,0.4570917855835725,-0.03766376468274858,0.4048059034205665,1.5805599528095038,3.244826799017829,3.4311305173075413,-0.03766376468274858,-0.05710757719101301
| 2,701
|
Endoplasmic reticulum golgi intermediate compartment membrane
| 15
| 19
| 2.308863
| 0.020951
|
P61019,P51572,Q9Y3A6,P24390,Q10472,Q9BVK6,Q9Y3B3,P49257,Q9Y282,P49755,Q15904,Q13190,Q15363,O15260,O95070
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
541,253,430,9,456,174,302,583,54,277,436,215,349,285,159
|
285,865,619,159,9,2356,583,277,253,541,456,801,215,349,436,174,54,430,302
|
1.1888955874119858,0.20754810800791113,0.47438206198749655,1.6992696820323683,3.6674600654956833,-0.8680821176442824,0.5258452995193653,1.2180780751359057,1.3044639973832475,0.593531179510868,0.742084510223003,0.28031310881637544,1.4308934785310223,0.9942651268493035,0.7744188751377666,1.6072235088664195,2.5574259051028014,0.8065146214158287,1.1447500131709183
| 2,701
|
Nail dysplasia
| 8
| 29
| 2.307081
| 0.02105
|
Q15149,P15924,P48651,O96028,P16615,P51812,O95202,P42892
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
198,14,175,210,252,372,405,155
|
414,1174,1977,405,210,563,14,252,685,981,850,1343,1740,1413,155,175,372,1613,1860,1290,198,780,1190,2369,1758,1165,1623,1095,933
|
0.8224740869191085,-0.03766376468274858,-0.5298892096352652,0.8383751777967641,1.4447157506111374,0.559819657694308,3.3434324737059566,1.3044639973832475,0.38723710682081225,0.11485486211702632,0.22585325728994807,-0.1357571511500396,-0.3805374686703146,-0.1756174312141384,1.7122602692585014,1.5939123156550052,0.9325789136855012,-0.2974182770678407,-0.4439252239854569,-0.09625596283480581,1.4859193366122214,0.2983165752789475,-0.03766376468274858,-0.8680821176442824,-0.3805374686703146,-0.01830586786658518,-0.2974182770678407,0.03925969392486323,0.17070624531058928
| 2,701
|
Inorganic anion transmembrane transporter activity
| 14
| 20
| 2.297243
| 0.021605
|
O15439,O43681,Q9Y277,Q9BXP2,Q4KMQ2,P04920,Q9Y6M7,Q9UBX3,Q9C0H2,P33527,P51790,P21796,P45880,Q02978
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
248,536,166,359,518,462,143,47,94,348,280,62,28,183
|
2227,248,536,462,62,348,28,280,813,183,518,1961,1836,566,359,94,47,166,2099,143
|
-0.7296754780456444,1.3186955452496854,0.593531179510868,0.7258267538427401,2.460444745964291,0.9942651268493035,2.905147117866422,1.203511402271728,0.2622351395530162,1.540253330753097,0.6269838228448695,-0.5082402040270202,-0.4226942464977029,0.559819657694308,0.9635315701724516,2.1321287594832308,2.6626661752675664,1.6862398498357258,-0.5954826549590951,1.802114682609706
| 2,701
|
Sensorimotor neuropathy
| 13
| 29
| 2.292042
| 0.021903
|
P00403,P07602,P41440,O60313,O00429,O95831,Q15120,Q9NR77,Q9NZJ7,Q9NSE4,P05023,Q9Y2R0,Q8N2K0
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
251,31,321,189,434,297,333,113,146,403,243,24,188
|
434,2071,189,297,251,243,1494,31,2217,1249,2659,1885,321,1253,1534,2341,2342,2028,1543,333,597,188,1400,2035,113,403,146,24,469
|
0.7744188751377666,-0.5954826549590951,1.5131717487404053,1.1447500131709183,1.3044639973832475,1.332880448717388,-0.23609532189713084,2.8458055936098234,-0.707024253971549,-0.07663805632366444,-1.8040386577143217,-0.4652592172226013,1.085181098032962,-0.07663805632366444,-0.25644127155135765,-0.8447106696636559,-0.8447106696636559,-0.5516452556198194,-0.25644127155135765,1.0550869617499012,0.5087582951969946,1.526733762162025,-0.1556420051329787,-0.5516452556198194,2.024912659220012,0.8542183112675076,1.7766325496335293,2.973351412079002,0.7258267538427401
| 2,701
|
Specific granule
| 9
| 28
| 2.291804
| 0.021917
|
Q08722,P30519,Q07065,Q4KMQ2,P14923,O00264,P51790,Q9Y5K8,Q6IAA8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
354,66,263,518,16,308,280,452,446
|
863,1465,308,1145,1495,16,911,66,1008,280,1213,263,354,529,1220,1717,1508,518,1226,446,704,921,843,2125,706,1516,788,452
|
0.20754810800791113,-0.21584326062426626,1.115067853889435,-0.01830586786658518,-0.23609532189713084,3.2538860606266975,0.17070624531058928,2.416626861835804,0.0960781397108018,1.203511402271728,-0.05710757719101301,1.2758597586554565,0.9789255457318856,0.6102896170952945,-0.05710757719101301,-0.3596097669606752,-0.23609532189713084,0.6269838228448695,-0.05710757719101301,0.7582817372111945,0.36959730040846983,0.17070624531058928,0.24408206050486364,-0.6175661397525806,0.36959730040846983,-0.23609532189713084,0.2983165752789475,0.7582817372111945
| 2,701
|
Cristae formation
| 7
| 9
| 2.288993
| 0.02208
|
Q16891,Q6UXV4,Q5XKP0,Q9Y512,Q9Y4W6,Q9BUR5,O95202
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
388,200,273,212,469,186,405
|
405,388,273,200,186,475,1335,469,212
|
0.8383751777967641,0.8857323527866384,1.2470652835370355,1.4859193366122214,1.540253330753097,0.7095080229146791,-0.11596206747168612,0.7258267538427401,1.4447157506111374
| 2,701
|
Protein transmembrane transport
| 14
| 22
| 2.275226
| 0.022892
|
Q9NS69,Q99595,Q9UGP8,Q9BVV7,Q3ZCQ8,P61619,Q15629,O95831,O96008,O14925,O75381,Q15388,P49755,Q07820
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,3,515,390,417,169,41,297,326,196,339,498,277,510
|
196,712,339,684,297,326,2654,980,277,516,1638,2142,169,510,498,41,417,3,390,2178,2,515
|
1.4859193366122214,0.351885919191322,1.0247826043693027,0.38723710682081225,1.1447500131709183,1.0701601286370668,-1.746524104659968,0.11485486211702632,1.2180780751359057,0.6269838228448695,-0.3180510829696362,-0.6397609283995005,1.6469125414193932,0.6436142777409396,0.6601814574178648,2.745032234471493,0.8224740869191085,4.492615277702867,0.8857323527866384,-0.6620681262993946,5.159139452386764,0.6436142777409396
| 2,701
|
Basal part of cell
| 19
| 49
| 2.272924
| 0.023031
|
Q9H2H9,P15924,Q9Y6M7,P57105,P07355,P41440,P35222,P04920,Q99808,P33527,P11166,P58107,P42785,P05023,O15439,O75955,P53985,Q14254,P35613
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
138,14,143,315,313,321,73,462,338,348,222,101,109,243,248,495,254,383,381
|
976,1465,1069,248,1975,495,937,808,890,462,243,1118,313,1044,960,222,1530,1245,1634,14,1701,1024,699,1879,348,73,381,321,109,254,624,315,101,677,2645,1890,529,1784,1785,1891,383,839,2151,1231,338,2156,138,681,143
|
0.11485486211702632,-0.21584326062426626,0.03925969392486323,1.3186955452496854,-0.5298892096352652,0.6601814574178648,0.15216824938562942,0.2622351395530162,0.18916598311737365,0.7258267538427401,1.332880448717388,0.000966854535827841,1.1001502232099265,0.05828124665914992,0.13355134211590133,1.4031156606893533,-0.25644127155135765,-0.07663805632366444,-0.3180510829696362,3.3434324737059566,-0.3596097669606752,0.07722049678650203,0.36959730040846983,-0.4652592172226013,0.9942651268493035,2.3276237027439657,0.9014040733816177,1.085181098032962,2.0489706294219476,1.3044639973832475,0.47438206198749655,1.1001502232099265,2.072894727430521,0.4048059034205665,-1.6616232828965283,-0.4652592172226013,0.6102896170952945,-0.40156531384122846,-0.40156531384122846,-0.4652592172226013,0.9014040733816177,0.24408206050486364,-0.6397609283995005,-0.05710757719101301,1.0399612405003023,-0.6397609283995005,1.8400575311170198,0.4048059034205665,1.802114682609706
| 2,701
|
Sphingolipid biosynthetic process
| 6
| 14
| 2.267813
| 0.023341
|
Q99805,O95470,P04062,Q06136,Q13510,Q96G23
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
202,144,177,18,119,27
|
1972,2071,144,177,797,18,119,1509,596,27,202,504,208,1168
|
-0.5298892096352652,-0.5954826549590951,1.7893924505266094,1.5805599528095038,0.28031310881637544,3.244826799017829,1.951920624080694,-0.23609532189713084,0.5087582951969946,2.92474561480173,1.4859193366122214,0.6601814574178648,1.4722284064322555,-0.01830586786658518
| 2,701
|
Intrinsic component of plasma membrane
| 42
| 76
| 2.260041
| 0.023819
|
O15118,Q96QD8,P35613,Q9H2H9,Q9UJS0,Q9UIQ6,P51790,Q9UNK0,Q9Y289,O00400,Q00325,O00264,P10321,Q02978,Q99797,Q8N2K0,P17152,P27824,Q8WTV0,P41440,Q9BTU6,Q99805,O60637,Q99808,P11279,Q92542,O96005,P33527,P11166,Q08722,P05141,Q13641,O95864,Q9NR28,Q9H0U3,O43657,P05023,O76062,P54709,P53985,P16615,P51572
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
130,389,381,138,666,142,280,282,681,170,551,308,563,183,317,188,320,570,322,321,324,202,77,338,80,599,85,348,222,354,605,355,479,489,238,107,243,620,624,254,252,253
|
1277,308,170,935,1811,1693,130,865,107,848,77,620,479,85,808,2105,243,1118,605,1043,563,1149,222,80,1601,750,252,320,1701,1024,1314,699,570,348,1920,381,1098,321,2574,253,280,254,624,677,551,183,354,801,1647,355,2390,2002,1129,839,842,1658,188,1296,921,1836,322,599,389,317,202,338,324,238,138,489,142,666,282,681,2133,862
|
-0.09625596283480581,1.115067853889435,1.6337233768883894,0.15216824938562942,-0.4226942464977029,-0.3596097669606752,1.8901336133115505,0.20754810800791113,2.0489706294219476,0.22585325728994807,2.2824196152272136,0.47438206198749655,0.6931278673873417,2.213707758412066,0.2622351395530162,-0.6175661397525806,1.332880448717388,0.000966854535827841,0.49160405626708076,0.05828124665914992,0.559819657694308,-0.01830586786658518,1.4031156606893533,2.248201202031891,-0.2974182770678407,0.31624613864460677,1.3044639973832475,1.085181098032962,-0.3596097669606752,0.07722049678650203,-0.11596206747168612,0.36959730040846983,0.5428655840352268,0.9942651268493035,-0.4866972109565579,0.9014040733816177,0.02015513431309902,1.085181098032962,-1.234355168597917,1.3044639973832475,1.203511402271728,1.3044639973832475,0.47438206198749655,0.4048059034205665,0.5767080236830171,1.540253330753097,0.9789255457318856,0.28031310881637544,-0.3180510829696362,0.9789255457318856,-0.8915779896099613,-0.5298892096352652,0.000966854535827841,0.24408206050486364,0.24408206050486364,-0.3180510829696362,1.526733762162025,-0.09625596283480581,0.17070624531058928,-0.4226942464977029,1.085181098032962,0.5087582951969946,0.8857323527866384,1.1001502232099265,1.4859193366122214,1.0399612405003023,1.085181098032962,1.3470190066264098,1.8400575311170198,0.676685832241666,1.8147994633249862,0.42230424858015453,1.203511402271728,0.4048059034205665,-0.6175661397525806,0.22585325728994807
| 2,701
|
Cardiac muscle contraction
| 8
| 19
| 2.259403
| 0.023858
|
P00403,P14406,O14949,P10606,P31930,P05023,Q9UDW1,P16615
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
251,1,65,298,81,243,118,252
|
65,251,243,1118,796,749,2505,1950,298,343,1,1471,252,1076,569,81,624,1643,118
|
2.4276234185896435,1.3044639973832475,1.332880448717388,0.000966854535827841,0.28031310881637544,0.31624613864460677,-1.1088623151263601,-0.5082402040270202,1.1447500131709183,1.0095506891404633,5.210648084460358,-0.21584326062426626,1.3044639973832475,0.03925969392486323,0.5428655840352268,2.248201202031891,0.47438206198749655,-0.3180510829696362,1.9763891703113325
| 2,701
|
Sulfur compound transport
| 8
| 11
| 2.252964
| 0.024261
|
Q8TB61,Q70HW3,O00400,Q9UBX3,O15439,Q9HC21,P33527,Q02978
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
136,11,170,47,248,220,348,183
|
170,248,348,183,11,136,1836,450,220,47,681
|
1.6337233768883894,1.3186955452496854,0.9942651268493035,1.540253330753097,3.617915206963102,1.8526312438376766,-0.4226942464977029,0.7582817372111945,1.417026875112562,2.6626661752675664,0.4048059034205665
| 2,701
|
Rhoa gtpase cycle
| 15
| 38
| 2.243373
| 0.024873
|
O15173,P41440,P30519,Q8NBN3,Q96HY6,O75955,P14923,Q14739,Q15904,Q13190,P42167,Q9H0H5,P28288,Q14254,P51572
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
127,321,66,90,270,495,16,53,436,215,379,450,470,383,253
|
863,1810,127,865,2209,495,1117,808,980,16,470,66,321,1923,379,985,583,253,1446,2360,215,2287,383,53,436,2086,842,90,2090,2241,690,270,450,2371,514,2095,1197,1462
|
0.20754810800791113,-0.4226942464977029,1.9025621688075542,0.20754810800791113,-0.707024253971549,0.6601814574178648,0.000966854535827841,0.2622351395530162,0.11485486211702632,3.2538860606266975,0.7095080229146791,2.416626861835804,1.085181098032962,-0.4866972109565579,0.9170194617840494,0.11485486211702632,0.5258452995193653,1.3044639973832475,-0.19568424190462033,-0.8680821176442824,1.4308934785310223,-0.7753301127313307,0.9014040733816177,2.5574259051028014,0.7744188751377666,-0.5954826549590951,0.24408206050486364,2.1672811097819484,-0.5954826549590951,-0.7296754780456444,0.38723710682081225,1.2614864555637981,0.7582817372111945,-0.8680821176442824,0.6436142777409396,-0.5954826549590951,-0.03766376468274858,-0.19568424190462033
| 2,701
|
Atpase coupled transmembrane transporter activity
| 11
| 22
| 2.24246
| 0.024932
|
P98194,P08183,P05023,P33527,O15439,Q9Y5K8,Q9HD20,P61421,P28288,P16615,O75027
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
178,180,243,348,248,452,58,471,470,252,371
|
248,371,243,1118,1568,180,252,1024,1343,1602,699,470,348,1882,2191,813,471,178,498,58,1433,452
|
1.3186955452496854,0.9325789136855012,1.332880448717388,0.000966854535827841,-0.27688196692354466,1.5537307142177417,1.3044639973832475,0.07722049678650203,-0.1357571511500396,-0.2974182770678407,0.36959730040846983,0.7095080229146791,0.9942651268493035,-0.4652592172226013,-0.6844888552895658,0.2622351395530162,0.7095080229146791,1.5805599528095038,0.6601814574178648,2.5038189105500694,-0.1756174312141384,0.7582817372111945
| 2,701
|
Sparse or absent eyelashes
| 7
| 23
| 2.235871
| 0.02536
|
O75844,Q14574,P15924,P14923,Q9H9Y6,P48449,P02545
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
43,13,14,16,306,83,214
|
1020,2298,1174,2314,43,214,1631,16,14,621,1571,1252,83,1449,1993,2144,1648,13,2536,1165,306,1623,318
|
0.07722049678650203,-0.7983359233670255,-0.03766376468274858,-0.8214623601730139,2.734822878575379,1.4308934785310223,-0.3180510829696362,3.2538860606266975,3.3434324737059566,0.47438206198749655,-0.27688196692354466,-0.07663805632366444,2.2367341600459416,-0.19568424190462033,-0.5298892096352652,-0.6397609283995005,-0.3180510829696362,3.4311305173075413,-1.1586332093664824,-0.01830586786658518,1.1299343362894672,-0.2974182770678407,1.1001502232099265
| 2,701
|
ER-Golgi transport
| 17
| 49
| 2.234406
| 0.025456
|
O95249,P51572,O14579,P62820,O95197,P24390,Q9Y678,Q9HCU5,O95487,Q9NR31,Q9Y282,P49755,Q9P2W9,Q12981,Q969M3,Q15363,O95070
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
225,253,293,517,10,9,106,534,304,275,54,277,181,543,376,349,159
|
293,1374,865,1241,1595,1974,619,1770,159,10,225,1567,304,1150,9,1499,1924,583,277,253,1674,1477,1992,2196,1009,541,1154,517,543,1323,349,2084,1161,1355,1035,1546,1106,1134,2090,1400,376,2175,534,275,181,765,54,2330,106
|
1.1595152238833708,-0.1556420051329787,0.20754810800791113,-0.07663805632366444,-0.2974182770678407,-0.5298892096352652,0.47438206198749655,-0.40156531384122846,1.6992696820323683,3.6262130177039786,1.3891595529580087,-0.27688196692354466,1.1299343362894672,-0.01830586786658518,3.6674600654956833,-0.23609532189713084,-0.4866972109565579,0.5258452995193653,1.2180780751359057,1.3044639973832475,-0.33878127776425015,-0.21584326062426626,-0.5298892096352652,-0.6844888552895658,0.0960781397108018,0.593531179510868,-0.01830586786658518,0.6269838228448695,0.593531179510868,-0.11596206747168612,0.9942651268493035,-0.5954826549590951,-0.01830586786658518,-0.1357571511500396,0.07722049678650203,-0.25644127155135765,0.02015513431309902,0.000966854535827841,-0.5954826549590951,-0.1556420051329787,0.9325789136855012,-0.6620681262993946,0.6102896170952945,1.2325959289574466,1.5537307142177417,0.31624613864460677,2.5574259051028014,-0.8214623601730139,2.060949321084514
| 2,701
|
Establishment of protein localization to mitochondrial membrane
| 6
| 15
| 2.232867
| 0.025558
|
Q9NS69,Q9P0J0,Q8WWC4,Q9Y5J9,Q9Y512,Q15070
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,133,140,209,212,56
|
696,826,684,1176,1497,2110,56,596,140,2,133,617,212,276,209
|
0.36959730040846983,0.24408206050486364,0.38723710682081225,-0.03766376468274858,-0.23609532189713084,-0.6175661397525806,2.5360636019540204,0.5087582951969946,1.8147994633249862,5.159139452386764,1.8901336133115505,0.49160405626708076,1.4447157506111374,1.2325959289574466,1.4722284064322555
| 2,701
|
Nucleobase containing compound transmembrane transporter activity
| 9
| 14
| 2.224952
| 0.026084
|
O15439,P41440,Q8TB61,O00400,Q99808,O43808,Q9H2D1,Q6NUK1,Q9HC21
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
248,321,136,170,338,147,22,344,220
|
825,170,248,147,605,750,415,321,591,344,136,338,22,220
|
0.24408206050486364,1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,0.5087582951969946,1.0095506891404633,1.8526312438376766,1.0399612405003023,3.1065707089213883,1.417026875112562
| 2,701
|
Microbody membrane
| 12
| 23
| 2.22279
| 0.02623
|
O15228,Q15067,Q9BY49,P50542,Q8TB36,Q9NR77,Q8NBU5,O75381,O43808,P28288,P51648,P40855
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
289,259,99,516,244,113,402,339,147,470,218,572
|
934,289,147,1309,339,1437,2019,470,1248,1571,572,516,218,1534,259,585,917,402,244,902,2174,99,113
|
0.15216824938562942,1.1742303044100273,1.7638347606018192,-0.11596206747168612,1.0247826043693027,-0.19568424190462033,-0.5516452556198194,0.7095080229146791,-0.07663805632366444,-0.27688196692354466,0.5428655840352268,0.6269838228448695,1.417026875112562,-0.25644127155135765,1.2901855033977274,0.5258452995193653,0.17070624531058928,0.8542183112675076,1.332880448717388,0.18916598311737365,-0.6620681262993946,2.0966864062402033,2.024912659220012
| 2,701
|
Oxidoreduction driven active transmembrane transporter activity
| 12
| 29
| 2.215183
| 0.026747
|
P00403,O96000,O43676,Q9P0J0,O95169,O95168,P10606,P31930,Q9UDW1,P13073,Q7KZN9,Q9Y6M9
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
251,290,4,133,295,325,298,81,118,343,152,30
|
2556,1115,4,1973,2516,478,1528,2230,325,295,2442,2017,290,251,749,298,343,2561,1076,2046,81,2608,1256,399,609,152,133,118,30
|
-1.2089703136081216,0.000966854535827841,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,1.1742303044100273,1.3044639973832475,0.31624613864460677,1.1447500131709183,1.0095506891404633,-1.2089703136081216,0.03925969392486323,-0.5735093847387928,2.248201202031891,-1.3635087831226131,-0.07663805632366444,0.8542183112675076,0.49160405626708076,1.7381246312443195,1.8901336133115505,1.9763891703113325,2.8557533308424374
| 2,701
|
Protein transmembrane transporter activity
| 8
| 10
| 2.213162
| 0.026886
|
Q9NS69,Q99595,O96008,P61619,O14925,Q15388,P49755,Q07820
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
2,3,326,169,196,498,277,510
|
196,684,326,277,169,510,498,3,2,515
|
1.4859193366122214,0.38723710682081225,1.0701601286370668,1.2180780751359057,1.6469125414193932,0.6436142777409396,0.6601814574178648,4.492615277702867,5.159139452386764,0.6436142777409396
| 2,701
|
Sparse eyebrow
| 8
| 27
| 2.207902
| 0.027251
|
O75844,Q14574,P15924,P14923,P48449,O75431,P02545,Q92643
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
43,13,14,16,83,309,214,287
|
1020,1279,309,2314,43,214,16,14,2443,621,1252,83,1448,731,1711,1449,2682,2144,1859,13,782,1326,287,439,1038,601,318
|
0.07722049678650203,-0.09625596283480581,1.115067853889435,-0.8214623601730139,2.734822878575379,1.4308934785310223,3.2538860606266975,3.3434324737059566,-0.9868321395764779,0.47438206198749655,-0.07663805632366444,2.2367341600459416,-0.19568424190462033,0.3341023914526849,-0.3596097669606752,-0.19568424190462033,-2.424109513901695,-0.6397609283995005,-0.4439252239854569,3.4311305173075413,0.2983165752789475,-0.11596206747168612,1.1888955874119858,0.7744188751377666,0.07722049678650203,0.5087582951969946,1.1001502232099265
| 2,701
|
Apoptotic mitochondrial changes
| 10
| 30
| 2.195223
| 0.028148
|
O60313,Q16611,Q3ZCQ8,Q9NT62,O75223,Q96A26,O75832,P02545,P45880,Q9H3K2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
189,37,417,391,261,48,303,214,28,223
|
434,826,189,261,303,214,1411,1096,605,2654,750,2046,2571,1497,636,2385,28,1985,870,37,417,1017,1396,1726,48,1232,1059,223,391,932
|
0.7744188751377666,0.24408206050486364,1.5131717487404053,1.2758597586554565,1.1299343362894672,1.4308934785310223,-0.1756174312141384,0.02015513431309902,0.49160405626708076,-1.746524104659968,0.31624613864460677,-0.5735093847387928,-1.234355168597917,-0.23609532189713084,0.4570917855835725,-0.8915779896099613,2.905147117866422,-0.5298892096352652,0.20754810800791113,2.775514718206515,0.8224740869191085,0.0960781397108018,-0.1556420051329787,-0.3596097669606752,2.620880275374442,-0.05710757719101301,0.05828124665914992,1.4031156606893533,0.8857323527866384,0.17070624531058928
| 2,701
|
Membrane lipid catabolic process
| 6
| 11
| 2.193421
| 0.028277
|
Q99735,P17900,P50897,O95470,P04062,Q13510
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
420,163,74,144,177,119
|
144,177,1022,1075,1281,829,163,74,119,420,504
|
1.7893924505266094,1.5805599528095038,0.07722049678650203,0.03925969392486323,-0.09625596283480581,0.24408206050486364,1.6862398498357258,2.3163672654572762,1.951920624080694,0.8224740869191085,0.6601814574178648
| 2,701
|
Cis golgi network
| 8
| 13
| 2.192813
| 0.028321
|
O95249,O00461,Q92538,Q9Y3A6,P24390,P98194,P49755,Q9NPR9
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
225,34,358,430,9,178,277,216
|
34,1595,225,9,1498,277,178,1354,445,2090,358,216,430
|
2.815822521189644,-0.2974182770678407,1.3891595529580087,3.6674600654956833,-0.23609532189713084,1.2180780751359057,1.5805599528095038,-0.1357571511500396,0.7582817372111945,-0.5954826549590951,0.9635315701724516,1.4308934785310223,0.8065146214158287
| 2,701
|
Secondary alcohol metabolic process
| 15
| 36
| 2.188018
| 0.028668
|
O15118,Q15392,Q9UBM7,Q8WTV0,P16435,Q14534,P37268,P61916,P48735,Q9BQE5,P04062,P48449,Q14739,Q16850,Q15800
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,131,36,322,441,327,69,72,329,12,177,83,53,278,409
|
130,1490,794,1310,620,1817,1696,177,1819,940,441,2216,69,2385,83,329,455,2662,1991,72,2266,2418,2471,327,53,2220,131,594,409,278,586,322,2552,12,36,2475
|
1.8901336133115505,-0.23609532189713084,0.28031310881637544,-0.11596206747168612,0.47438206198749655,-0.4226942464977029,-0.3596097669606752,1.5805599528095038,-0.4226942464977029,0.15216824938562942,0.7582817372111945,-0.707024253971549,2.3945487262934133,-0.8915779896099613,2.2367341600459416,1.0550869617499012,0.742084510223003,-1.8330771393386691,-0.5298892096352652,2.36121680514361,-0.7524437006538256,-0.9389482483908096,-1.035240699093695,1.0701601286370668,2.5574259051028014,-0.707024253971549,1.8901336133115505,0.5087582951969946,0.8383751777967641,1.2180780751359057,0.5258452995193653,1.085181098032962,-1.183730197015092,3.5509413806281707,2.8057811853844417,-1.035240699093695
| 2,701
|
Endocytic vesicle membrane
| 11
| 33
| 2.184997
| 0.028889
|
Q8WTV0,P51151,Q9Y487,Q12846,Q15907,P11279,Q5KU26,Q14108,P10321,Q93050,P61421
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
322,164,134,529,266,80,597,21,563,91,471
|
863,619,713,1737,808,2105,563,80,1601,1671,1314,2356,1474,774,164,963,1350,471,1608,1611,1219,529,1506,1053,21,1129,266,597,322,91,761,926,134
|
0.20754810800791113,0.47438206198749655,0.351885919191322,-0.3805374686703146,0.2622351395530162,-0.6175661397525806,0.559819657694308,2.248201202031891,-0.2974182770678407,-0.33878127776425015,-0.11596206747168612,-0.8680821176442824,-0.21584326062426626,0.2983165752789475,1.6862398498357258,0.13355134211590133,-0.1357571511500396,0.7095080229146791,-0.2974182770678407,-0.2974182770678407,-0.05710757719101301,0.6102896170952945,-0.23609532189713084,0.05828124665914992,3.1159288248830843,0.000966854535827841,1.2614864555637981,0.5087582951969946,1.085181098032962,2.1672811097819484,0.31624613864460677,0.17070624531058928,1.8901336133115505
| 2,701
|
Ectopic calcification
| 14
| 43
| 2.177439
| 0.029448
|
P00403,O15228,O60313,Q9UBM7,P35222,O75844,P04062,P38435,O75381,Q14739,O75431,P02545,P23786,P11166
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
251,289,189,36,73,43,177,114,339,53,309,214,182,222
|
934,434,1766,289,2298,189,1174,2253,339,309,43,1668,251,214,177,1915,342,2256,222,2282,981,850,182,73,114,2509,572,2051,516,1534,963,1316,2387,53,1786,594,2404,1760,1623,1805,36,1239,2409
|
0.15216824938562942,0.7744188751377666,-0.40156531384122846,1.1742303044100273,-0.7983359233670255,1.5131717487404053,-0.03766376468274858,-0.7524437006538256,1.0247826043693027,1.115067853889435,2.734822878575379,-0.33878127776425015,1.3044639973832475,1.4308934785310223,1.5805599528095038,-0.4866972109565579,1.0095506891404633,-0.7524437006538256,1.4031156606893533,-0.7753301127313307,0.11485486211702632,0.22585325728994807,1.540253330753097,2.3276237027439657,2.0128330114691035,-1.1088623151263601,0.5428655840352268,-0.5735093847387928,0.6269838228448695,-0.25644127155135765,0.13355134211590133,-0.11596206747168612,-0.8915779896099613,2.5574259051028014,-0.40156531384122846,0.5087582951969946,-0.9151995911546438,-0.3805374686703146,-0.2974182770678407,-0.40156531384122846,2.8057811853844417,-0.05710757719101301,-0.9151995911546438
| 2,701
|
Outer membrane
| 38
| 78
| 2.173533
| 0.02974
|
O43169,Q9NS69,Q16891,Q9NQZ5,Q5XKP0,Q9NZJ7,Q8NBU5,Q6NUM9,P45880,Q8N4H5,Q9UBM7,Q16611,Q9Y277,Q13505,Q709C8,O00264,O75431,Q9BUR5,O00429,P57105,P21796,Q96TC7,O60313,P30536,Q6UXV4,Q99536,O96008,Q15149,P50402,Q9Y512,Q9BUK6,Q9NVH1,Q9Y6C9,Q99720,Q8TB36,Q99623,Q9NXE4,Q15388
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,2,388,265,273,146,402,151,28,32,36,37,166,296,173,308,309,186,434,315,62,64,189,195,200,323,326,198,197,212,211,475,92,501,244,245,504,498
|
308,434,2698,0,189,1309,309,684,1437,326,1696,2211,715,672,1246,62,195,1248,2632,2594,912,1825,28,2574,197,870,2342,315,2167,510,1542,296,2267,198,498,37,388,596,817,273,151,200,173,917,545,1017,1396,1456,32,969,402,244,649,1230,950,64,323,245,501,211,186,1059,727,2588,265,693,2,1234,475,1335,504,146,36,1065,166,1522,212,92
|
1.115067853889435,0.7744188751377666,-4.819863517888487,5.210648084460358,1.5131717487404053,-0.11596206747168612,1.115067853889435,0.38723710682081225,-0.19568424190462033,1.0701601286370668,-0.3596097669606752,-0.707024253971549,0.351885919191322,0.4048059034205665,-0.07663805632366444,2.460444745964291,1.4995670283946096,-0.07663805632366444,-1.5508878008702094,-1.3373751235719122,0.17070624531058928,-0.4226942464977029,2.905147117866422,-1.234355168597917,1.4859193366122214,0.20754810800791113,-0.8447106696636559,1.1001502232099265,-0.6620681262993946,0.6436142777409396,-0.25644127155135765,1.1595152238833708,-0.7524437006538256,1.4859193366122214,0.6601814574178648,2.775514718206515,0.8857323527866384,0.5087582951969946,0.2622351395530162,1.2470652835370355,1.7509988621945363,1.4859193366122214,1.6072235088664195,0.17070624531058928,0.593531179510868,0.0960781397108018,-0.1556420051329787,-0.19568424190462033,2.8458055936098234,0.13355134211590133,0.8542183112675076,1.332880448717388,0.439732694154855,-0.05710757719101301,0.15216824938562942,2.4385918243920237,1.085181098032962,1.332880448717388,0.6601814574178648,1.4447157506111374,1.540253330753097,0.05828124665914992,0.351885919191322,-1.3113946688909883,1.2758597586554565,0.38723710682081225,5.159139452386764,-0.05710757719101301,0.7095080229146791,-0.11596206747168612,0.6601814574178648,1.7766325496335293,2.8057811853844417,0.05828124665914992,1.6862398498357258,-0.23609532189713084,1.4447157506111374,2.1555955949755234
| 2,701
|
Golgi associated vesicle
| 8
| 28
| 2.172273
| 0.029835
|
O14579,P24390,Q9Y678,Q9BVK6,Q9Y3B3,P49755,Q8TCT8,Q15363
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
293,9,106,174,302,277,250,349
|
293,1376,1737,2188,698,1601,9,1499,983,1924,277,675,1674,1477,1350,416,1154,1611,1219,349,250,2090,174,1802,1521,765,302,106
|
1.1595152238833708,-0.1556420051329787,-0.3805374686703146,-0.6844888552895658,0.36959730040846983,-0.2974182770678407,3.6674600654956833,-0.23609532189713084,0.11485486211702632,-0.4866972109565579,1.2180780751359057,0.4048059034205665,-0.33878127776425015,-0.21584326062426626,-0.1357571511500396,0.8224740869191085,-0.01830586786658518,-0.2974182770678407,-0.05710757719101301,0.9942651268493035,1.3186955452496854,-0.5954826549590951,1.6072235088664195,-0.40156531384122846,-0.23609532189713084,0.31624613864460677,1.1447500131709183,2.060949321084514
| 2,701
|
Skin nodule
| 13
| 20
| 2.168734
| 0.030103
|
P11802,Q9NZ08,P48735,P35222,P35637,Q13510,Q9Y2U8,Q9NSE4,P16615,Q8NBM4,P21912,P31749,P52732
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
606,360,329,73,364,119,806,403,252,738,314,636,676
|
1310,1075,606,252,314,636,73,364,329,812,676,1219,1081,119,1161,738,1299,403,360,806
|
-0.11596206747168612,0.03925969392486323,0.49160405626708076,1.3044639973832475,1.1001502232099265,0.4570917855835725,2.3276237027439657,0.9480828206502808,1.0550869617499012,0.2622351395530162,0.4048059034205665,-0.05710757719101301,0.03925969392486323,1.951920624080694,-0.01830586786658518,0.3341023914526849,-0.09625596283480581,0.8542183112675076,0.9635315701724516,0.28031310881637544
| 2,701
|
Mitochondrial transport
| 30
| 73
| 2.16844
| 0.030125
|
Q9NS69,Q99595,Q9P0J0,Q9BVV7,Q8WWC4,P55786,Q9Y5J7,P56385,P45880,Q8N4H5,Q10713,Q16611,Q3ZCQ8,O95831,Q5JRX3,Q9UBX3,O75431,Q15070,Q99797,P23786,O75964,P30536,O96008,O14925,Q9Y5J9,Q9Y512,Q6NUK1,O43772,Q8TB36,P51572
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,3,133,390,140,17,276,407,28,32,161,37,417,297,425,47,309,56,317,182,57,195,326,196,209,212,344,103,244,253
|
1306,826,196,712,103,309,1493,2015,57,684,1771,297,326,1096,605,1568,1176,715,2654,750,2636,182,622,2337,2571,1497,195,2110,1777,2385,28,2573,583,2574,253,870,17,2306,407,2319,161,56,498,37,417,596,425,344,992,1017,1396,32,244,140,439,1232,1839,3,317,390,1059,2178,2,133,2069,47,666,766,617,1522,212,276,209
|
-0.11596206747168612,0.24408206050486364,1.4859193366122214,0.351885919191322,2.060949321084514,1.115067853889435,-0.23609532189713084,-0.5516452556198194,2.5038189105500694,0.38723710682081225,-0.40156531384122846,1.1447500131709183,1.0701601286370668,0.02015513431309902,0.49160405626708076,-0.27688196692354466,-0.03766376468274858,0.351885919191322,-1.746524104659968,0.31624613864460677,-1.5783139411225788,1.540253330753097,0.47438206198749655,-0.8447106696636559,-1.234355168597917,-0.23609532189713084,1.4995670283946096,-0.6175661397525806,-0.40156531384122846,-0.8915779896099613,2.905147117866422,-1.234355168597917,0.5258452995193653,-1.234355168597917,1.3044639973832475,0.20754810800791113,3.244826799017829,-0.7983359233670255,0.8383751777967641,-0.8214623601730139,1.6992696820323683,2.5360636019540204,0.6601814574178648,2.775514718206515,0.8224740869191085,0.5087582951969946,0.8065146214158287,1.0095506891404633,0.11485486211702632,0.0960781397108018,-0.1556420051329787,2.8458055936098234,1.332880448717388,1.8147994633249862,0.7744188751377666,-0.05710757719101301,-0.4226942464977029,4.492615277702867,1.1001502232099265,0.8857323527866384,0.05828124665914992,-0.6620681262993946,5.159139452386764,1.8901336133115505,-0.5735093847387928,2.6626661752675664,0.42230424858015453,0.31624613864460677,0.49160405626708076,-0.23609532189713084,1.4447157506111374,1.2325959289574466,1.4722284064322555
| 2,701
|
Alopecia
| 8
| 37
| 2.166382
| 0.030282
|
Q15149,O75844,P15924,P14923,Q06136,P48449,O75431,P02545
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
198,43,14,16,18,83,309,214
|
312,1174,1814,309,43,1668,526,214,1631,1915,16,14,685,981,850,1413,1252,83,2660,1449,1783,18,1450,457,1223,198,594,1190,1191,2270,1165,2273,1689,1623,2037,2582,617
|
1.1001502232099265,-0.03766376468274858,-0.4226942464977029,1.115067853889435,2.734822878575379,-0.33878127776425015,0.6102896170952945,1.4308934785310223,-0.3180510829696362,-0.4866972109565579,3.2538860606266975,3.3434324737059566,0.38723710682081225,0.11485486211702632,0.22585325728994807,-0.1756174312141384,-0.07663805632366444,2.2367341600459416,-1.8040386577143217,-0.19568424190462033,-0.40156531384122846,3.244826799017829,-0.19568424190462033,0.742084510223003,-0.05710757719101301,1.4859193366122214,0.5087582951969946,-0.03766376468274858,-0.03766376468274858,-0.7524437006538256,-0.01830586786658518,-0.7524437006538256,-0.33878127776425015,-0.2974182770678407,-0.5516452556198194,-1.2855656677675014,0.49160405626708076
| 2,701
|
Outer mitochondrial membrane protein complex
| 12
| 16
| 2.159346
| 0.030823
|
Q9NS69,Q16891,Q6UXV4,Q13505,O96008,Q5XKP0,Q9Y512,Q15388,O75431,Q9BUR5,Q9NVH1,Q8N4H5
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
2,388,200,296,326,273,212,498,309,186,475,32
|
309,684,326,2594,296,498,388,273,200,545,32,186,2,475,1335,212
|
1.115067853889435,0.38723710682081225,1.0701601286370668,-1.3373751235719122,1.1595152238833708,0.6601814574178648,0.8857323527866384,1.2470652835370355,1.4859193366122214,0.593531179510868,2.8458055936098234,1.540253330753097,5.159139452386764,0.7095080229146791,-0.11596206747168612,1.4447157506111374
| 2,701
|
Purine nucleotide transmembrane transporter activity
| 7
| 10
| 2.144273
| 0.032011
|
O15439,P41440,Q8TB61,O00400,Q99808,O43808,Q6NUK1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
248,321,136,170,338,147,344
|
170,248,147,605,750,415,321,344,136,338
|
1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,1.0095506891404633,1.8526312438376766,1.0399612405003023
| 2,701
|
Abnormality of the larynx
| 13
| 42
| 2.143506
| 0.032072
|
P07602,Q9UBM7,Q99700,Q9UHX1,P35637,Q96HY6,Q9NZJ7,P21964,Q14739,P02545,Q13510,Q15165,Q92804
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
31,36,201,362,364,270,146,82,53,214,119,125,447
|
1020,2253,1117,214,1096,31,1597,1599,441,1740,82,717,364,1882,1883,2263,1704,1185,1008,1476,1992,2341,1011,1478,119,678,53,1127,125,2536,1960,1656,1618,2525,447,1485,270,201,146,2037,36,362
|
0.07722049678650203,-0.7524437006538256,0.000966854535827841,1.4308934785310223,0.02015513431309902,2.8458055936098234,-0.2974182770678407,-0.2974182770678407,0.7582817372111945,-0.3805374686703146,2.2367341600459416,0.351885919191322,0.9480828206502808,-0.4652592172226013,-0.4652592172226013,-0.7524437006538256,-0.3596097669606752,-0.03766376468274858,0.0960781397108018,-0.21584326062426626,-0.5298892096352652,-0.8447106696636559,0.0960781397108018,-0.21584326062426626,1.951920624080694,0.4048059034205665,2.5574259051028014,0.000966854535827841,1.9273121495158725,-1.1586332093664824,-0.5082402040270202,-0.3180510829696362,-0.2974182770678407,-1.1336777677321255,0.7582817372111945,-0.21584326062426626,1.2614864555637981,1.4859193366122214,1.7766325496335293,-0.5516452556198194,2.8057811853844417,0.9635315701724516
| 2,701
|
Phagocytic vesicle
| 11
| 34
| 2.138075
| 0.032511
|
P61106,P51151,Q9Y487,Q12846,Q15907,P11279,P51790,Q93050,Q9UNK0,P61421,P08670
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
416,164,134,529,266,80,280,91,282,471,286
|
976,863,1465,1203,1071,2253,619,2105,286,563,80,1671,2356,2262,1182,912,1474,1008,774,164,280,1448,1350,416,471,1219,529,1053,266,721,91,926,282,134
|
0.11485486211702632,0.20754810800791113,-0.21584326062426626,-0.05710757719101301,0.03925969392486323,-0.7524437006538256,0.47438206198749655,-0.6175661397525806,1.1888955874119858,0.559819657694308,2.248201202031891,-0.33878127776425015,-0.8680821176442824,-0.7524437006538256,-0.03766376468274858,0.17070624531058928,-0.21584326062426626,0.0960781397108018,0.2983165752789475,1.6862398498357258,1.203511402271728,-0.19568424190462033,-0.1357571511500396,0.8224740869191085,0.7095080229146791,-0.05710757719101301,0.6102896170952945,0.05828124665914992,1.2614864555637981,0.351885919191322,2.1672811097819484,0.17070624531058928,1.203511402271728,1.8901336133115505
| 2,701
|
Muscle abnormality related to mitochondrial dysfunction
| 9
| 27
| 2.134291
| 0.032819
|
P00403,O96000,O60313,O43676,Q86Y39,Q9UBX3,Q9BUK6,Q9Y2R0,Q9Y6M9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
251,290,189,4,104,47,211,24,30
|
2556,1115,4,189,2516,478,1528,398,290,251,750,2561,2046,1825,2608,2195,596,104,2367,1138,211,307,1235,47,24,1170,30
|
-1.2089703136081216,0.000966854535827841,4.14073910845815,1.5131717487404053,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,0.8542183112675076,1.1742303044100273,1.3044639973832475,0.31624613864460677,-1.2089703136081216,-0.5735093847387928,-0.4226942464977029,-1.3635087831226131,-0.6844888552895658,0.5087582951969946,2.060949321084514,-0.8680821176442824,0.000966854535827841,1.4447157506111374,1.1299343362894672,-0.05710757719101301,2.6626661752675664,2.973351412079002,-0.01830586786658518,2.8557533308424374
| 2,701
|
Class i peroxisomal membrane protein import
| 7
| 8
| 2.134271
| 0.032821
|
Q8TB36,Q9NR77,Q8NBU5,O75381,O43808,P51648,P28288
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
244,113,402,339,147,218,470
|
147,339,470,572,218,402,244,113
|
1.7638347606018192,1.0247826043693027,0.7095080229146791,0.5428655840352268,1.417026875112562,0.8542183112675076,1.332880448717388,2.024912659220012
| 2,701
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 13
| 28
| 2.1303
| 0.033147
|
Q32P28,P13674,Q9BU89,O60568,P30519,Q6UW02,P16435,Q8NB78,Q14534,O00767,Q16850,Q15800,O15460
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
472,257,67,414,66,165,441,427,327,335,278,409,312
|
2679,335,312,1279,414,2229,1469,479,979,672,257,441,1820,66,1318,1645,1262,327,409,278,472,1417,165,2522,427,67,1366,1067
|
-2.3580812473620907,1.0399612405003023,1.1001502232099265,-0.09625596283480581,0.8224740869191085,-0.7296754780456444,-0.21584326062426626,0.6931278673873417,0.11485486211702632,0.4048059034205665,1.2901855033977274,0.7582817372111945,-0.4226942464977029,2.416626861835804,-0.11596206747168612,-0.3180510829696362,-0.07663805632366444,1.0701601286370668,0.8383751777967641,1.2180780751359057,0.7095080229146791,-0.1756174312141384,1.6862398498357258,-1.1336777677321255,0.8065146214158287,2.416626861835804,-0.1357571511500396,0.05828124665914992
| 2,701
|
Macromolecule transmembrane transporter activity
| 8
| 11
| 2.122153
| 0.033825
|
Q9NS69,Q99595,O96008,P61619,O14925,Q15388,P49755,Q07820
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
2,3,326,169,196,498,277,510
|
196,684,326,277,591,169,510,498,3,2,515
|
1.4859193366122214,0.38723710682081225,1.0701601286370668,1.2180780751359057,0.5087582951969946,1.6469125414193932,0.6436142777409396,0.6601814574178648,4.492615277702867,5.159139452386764,0.6436142777409396
| 2,701
|
Endoplasmic reticulum membrane organization
| 6
| 8
| 2.118208
| 0.034157
|
Q8NHH9,Q00765,Q9P2W9,Q12981,Q9NQC3,Q15363
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
512,395,181,543,122,349
|
1117,395,543,349,586,512,122,181
|
0.000966854535827841,0.8700039001223019,0.593531179510868,0.9942651268493035,0.5258452995193653,0.6436142777409396,1.93963397583531,1.5537307142177417
| 2,701
|
Purine nucleotide transport
| 8
| 12
| 2.109385
| 0.034911
|
O15439,Q08722,P41440,Q8TB61,O00400,Q99808,O43808,Q6NUK1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
248,354,321,136,170,338,147,344
|
170,248,147,605,750,415,321,354,344,136,1836,338
|
1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,0.31624613864460677,0.8224740869191085,1.085181098032962,0.9789255457318856,1.0095506891404633,1.8526312438376766,-0.4226942464977029,1.0399612405003023
| 2,701
|
Organelle fusion
| 21
| 39
| 2.106366
| 0.035173
|
Q12846,Q12981,Q9UNK0,Q8IWA4,O95721,P51153,Q16611,P06493,O15400,Q9H269,P07355,O60313,Q99536,Q86Y82,Q9Y4W6,Q13190,Q9Y6C9,O95249,Q8TB36,Q969M3,O75396
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
529,543,282,545,538,675,37,562,561,707,313,189,323,721,469,215,92,225,244,376,619
|
863,561,189,866,1974,619,225,538,808,890,562,313,1002,774,675,1350,529,543,215,37,992,721,545,244,1086,376,323,1059,707,2588,1335,1589,2407,766,1909,282,2039,469,92
|
0.20754810800791113,0.559819657694308,1.5131717487404053,0.20754810800791113,-0.5298892096352652,0.47438206198749655,1.3891595529580087,0.593531179510868,0.2622351395530162,0.18916598311737365,0.559819657694308,1.1001502232099265,0.0960781397108018,0.2983165752789475,0.4048059034205665,-0.1357571511500396,0.6102896170952945,0.593531179510868,1.4308934785310223,2.775514718206515,0.11485486211702632,0.351885919191322,0.593531179510868,1.332880448717388,0.03925969392486323,0.9325789136855012,1.085181098032962,0.05828124665914992,0.36959730040846983,-1.3113946688909883,-0.11596206747168612,-0.27688196692354466,-0.9151995911546438,0.31624613864460677,-0.4652592172226013,1.203511402271728,-0.5516452556198194,0.7258267538427401,2.1555955949755234
| 2,701
|
Metalloprotease
| 11
| 26
| 2.098587
| 0.035853
|
P09960,O43847,Q9NZ08,O75844,Q5JRX3,Q9UIQ6,P55786,Q96TA2,Q9Y4W6,Q99797,P42892
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
226,486,360,43,425,142,17,500,469,317,155
|
1913,486,1493,43,1470,714,226,2642,1245,155,1535,17,425,880,1796,2091,500,317,533,1369,1331,1370,1040,360,142,469
|
-0.4866972109565579,0.676685832241666,-0.23609532189713084,2.734822878575379,-0.21584326062426626,0.351885919191322,1.3891595529580087,-1.6336795739285952,-0.07663805632366444,1.7122602692585014,-0.25644127155135765,3.244826799017829,0.8065146214158287,0.20754810800791113,-0.40156531384122846,-0.5954826549590951,0.6601814574178648,1.1001502232099265,0.6102896170952945,-0.1357571511500396,-0.11596206747168612,-0.1357571511500396,0.07722049678650203,0.9635315701724516,1.8147994633249862,0.7258267538427401
| 2,701
|
Translocation
| 14
| 45
| 2.095182
| 0.036155
|
Q9NS69,Q99595,Q9BVV7,Q3ZCQ8,P61619,Q15629,Q92621,Q12769,O14925,Q9Y5J9,Q9Y5J7,Q9BTX1,O75381,Q8NFH4
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
2,3,390,417,169,41,428,487,196,209,276,148,339,249
|
976,196,712,339,1001,1177,1604,2050,1887,851,2112,1009,835,1638,169,2167,1782,487,41,417,1015,782,1897,647,249,1756,2291,1898,1514,1684,428,1869,1459,3,148,1799,390,611,514,2,1729,1590,2096,276,209
|
0.11485486211702632,1.4859193366122214,0.351885919191322,1.0247826043693027,0.0960781397108018,-0.03766376468274858,-0.2974182770678407,-0.5735093847387928,-0.4652592172226013,0.22585325728994807,-0.6175661397525806,0.0960781397108018,0.24408206050486364,-0.3180510829696362,1.6469125414193932,-0.6620681262993946,-0.40156531384122846,0.676685832241666,2.745032234471493,0.8224740869191085,0.0960781397108018,0.2983165752789475,-0.4652592172226013,0.439732694154855,1.3186955452496854,-0.3805374686703146,-0.7753301127313307,-0.4652592172226013,-0.23609532189713084,-0.33878127776425015,0.8065146214158287,-0.4439252239854569,-0.19568424190462033,4.492615277702867,1.7638347606018192,-0.40156531384122846,0.8857323527866384,0.49160405626708076,0.6436142777409396,5.159139452386764,-0.3596097669606752,-0.27688196692354466,-0.5954826549590951,1.2325959289574466,1.4722284064322555
| 2,701
|
Inner mitochondrial membrane protein complex
| 34
| 70
| 2.093494
| 0.036305
|
P00403,P14406,Q99595,O43676,Q9P0J0,Q9BVV7,Q16891,Q16718,Q5XKP0,Q9Y5J7,P56385,Q9Y6M9,O96000,Q13505,Q3ZCQ8,P12236,O95169,P10606,O75431,Q9BUR5,O75964,P21912,O14949,Q6UXV4,O95168,O14925,P31930,Q9Y512,Q9Y4W6,P13073,Q9NVH1,Q86Y39,Q99623,Q9UDW1
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
251,1,3,4,133,390,388,399,273,276,407,30,290,296,417,415,295,298,309,186,57,314,65,200,325,196,81,212,469,343,475,104,245,118
|
2556,1115,196,65,4,1973,2516,478,309,1528,2015,57,2230,325,295,2442,2017,290,251,1568,749,1950,298,415,343,1,1471,2561,1076,314,569,622,2337,2046,2397,81,1920,1777,2594,2573,2608,1256,2306,407,296,399,609,388,417,596,273,200,104,598,742,3,245,906,186,390,2178,475,1335,133,118,617,469,212,276,30
|
-1.2089703136081216,0.000966854535827841,1.4859193366122214,2.4276234185896435,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,1.115067853889435,-0.25644127155135765,-0.5516452556198194,2.5038189105500694,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,1.1742303044100273,1.3044639973832475,-0.27688196692354466,0.31624613864460677,-0.5082402040270202,1.1447500131709183,0.8224740869191085,1.0095506891404633,5.210648084460358,-0.21584326062426626,-1.2089703136081216,0.03925969392486323,1.1001502232099265,0.5428655840352268,0.47438206198749655,-0.8447106696636559,-0.5735093847387928,-0.9151995911546438,2.248201202031891,-0.4866972109565579,-0.40156531384122846,-1.3373751235719122,-1.234355168597917,-1.3635087831226131,-0.07663805632366444,-0.7983359233670255,0.8383751777967641,1.1595152238833708,0.8542183112675076,0.49160405626708076,0.8857323527866384,0.8224740869191085,0.5087582951969946,1.2470652835370355,1.4859193366122214,2.060949321084514,0.5087582951969946,0.3341023914526849,4.492615277702867,1.332880448717388,0.18916598311737365,1.540253330753097,0.8857323527866384,-0.6620681262993946,0.7095080229146791,-0.11596206747168612,1.8901336133115505,1.9763891703113325,0.49160405626708076,0.7258267538427401,1.4447157506111374,1.2325959289574466,2.8557533308424374
| 2,701
|
Endoplasmic reticulum to golgi vesicle mediated transport
| 24
| 62
| 2.085024
| 0.037067
|
Q8NHH9,P62820,P24390,Q9HCU5,O75340,Q9NR31,P49755,O95070,O14579,Q9Y3A6,Q9BVK6,Q9Y3B3,O95487,Q9Y282,Q9P2W9,Q96PC5,Q13190,Q7Z7H5,Q15363,O95249,Q92538,Q9Y678,Q969M3,P51572
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
512,517,9,534,272,275,277,159,293,430,174,302,304,54,181,328,215,219,349,225,358,106,376,253
|
1407,293,1374,865,1241,1595,1974,272,619,1770,159,225,1117,1567,304,1150,9,1499,1924,583,277,253,1674,1477,1992,2341,1009,541,517,801,215,1323,349,2084,1161,1355,1035,1546,219,1106,512,2090,358,1400,376,328,174,534,1802,275,1168,181,765,1967,1236,54,2330,430,302,2248,106,711
|
-0.1756174312141384,1.1595152238833708,-0.1556420051329787,0.20754810800791113,-0.07663805632366444,-0.2974182770678407,-0.5298892096352652,1.2470652835370355,0.47438206198749655,-0.40156531384122846,1.6992696820323683,1.3891595529580087,0.000966854535827841,-0.27688196692354466,1.1299343362894672,-0.01830586786658518,3.6674600654956833,-0.23609532189713084,-0.4866972109565579,0.5258452995193653,1.2180780751359057,1.3044639973832475,-0.33878127776425015,-0.21584326062426626,-0.5298892096352652,-0.8447106696636559,0.0960781397108018,0.593531179510868,0.6269838228448695,0.28031310881637544,1.4308934785310223,-0.11596206747168612,0.9942651268493035,-0.5954826549590951,-0.01830586786658518,-0.1357571511500396,0.07722049678650203,-0.25644127155135765,1.417026875112562,0.02015513431309902,0.6436142777409396,-0.5954826549590951,0.9635315701724516,-0.1556420051329787,0.9325789136855012,1.0701601286370668,1.6072235088664195,0.6102896170952945,-0.40156531384122846,1.2325959289574466,-0.01830586786658518,1.5537307142177417,0.31624613864460677,-0.5082402040270202,-0.05710757719101301,2.5574259051028014,-0.8214623601730139,0.8065146214158287,1.1447500131709183,-0.7296754780456444,2.060949321084514,0.36959730040846983
| 2,701
|
Biliary tract abnormality
| 13
| 24
| 2.083721
| 0.037186
|
P07602,Q10713,O43681,P50542,Q93008,Q5XKP0,Q9NZJ7,P04062,Q14739,Q14108,O96028,P02545,O95202
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
31,161,536,516,557,273,146,177,53,21,210,214,405
|
536,405,210,214,177,31,672,716,2570,1883,516,1534,161,2168,1613,21,53,273,557,1760,146,1560,617,997
|
0.593531179510868,0.8383751777967641,1.4447157506111374,1.4308934785310223,1.5805599528095038,2.8458055936098234,0.4048059034205665,0.351885919191322,-1.234355168597917,-0.4652592172226013,0.6269838228448695,-0.25644127155135765,1.6992696820323683,-0.6620681262993946,-0.2974182770678407,3.1159288248830843,2.5574259051028014,1.2470652835370355,0.5767080236830171,-0.3805374686703146,1.7766325496335293,-0.25644127155135765,0.49160405626708076,0.11485486211702632
| 2,701
|
Protein localization to endoplasmic reticulum
| 9
| 29
| 2.072975
| 0.038175
|
Q9NQC3,P61619,P24390,Q15629,P61009,Q96HY6,Q15005,Q9Y5M8,P51572
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
122,169,9,41,299,270,316,158,253
|
1374,523,536,1489,1205,2281,961,9,1572,1210,2166,253,1638,2052,299,2142,169,316,41,1355,2691,738,358,270,122,1168,515,1198,158
|
-0.1556420051329787,0.6102896170952945,0.593531179510868,-0.23609532189713084,-0.05710757719101301,-0.7753301127313307,0.13355134211590133,3.6674600654956833,-0.27688196692354466,-0.05710757719101301,-0.6620681262993946,1.3044639973832475,-0.3180510829696362,-0.5735093847387928,1.1447500131709183,-0.6397609283995005,1.6469125414193932,1.1001502232099265,2.745032234471493,-0.1357571511500396,-2.878787438217548,0.3341023914526849,0.9635315701724516,1.2614864555637981,1.93963397583531,-0.01830586786658518,0.6436142777409396,-0.03766376468274858,1.7122602692585014
| 2,701
|
Polyneuropathy
| 7
| 15
| 2.071453
| 0.038316
|
P07602,O60313,O95831,P31930,Q9NZJ7,Q9HC21,Q8N2K0
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
31,189,297,81,146,220,188
|
189,538,297,1022,31,2282,621,81,1011,333,879,188,220,146,1907
|
1.5131717487404053,0.593531179510868,1.1447500131709183,0.07722049678650203,2.8458055936098234,-0.7753301127313307,0.47438206198749655,2.248201202031891,0.0960781397108018,1.0550869617499012,0.20754810800791113,1.526733762162025,1.417026875112562,1.7766325496335293,-0.4652592172226013
| 2,701
|
metalloprotease
| 13
| 25
| 2.070203
| 0.038433
|
Q10713,O43847,Q9NZ08,O75844,Q5JRX3,Q9UIQ6,Q9BYT8,P55786,P31930,Q96TA2,Q9Y4W6,Q99797,P42892
|
Functions
|
Panther Protein class
|
panther_protein_class
|
161,486,360,43,425,142,533,17,81,500,469,317,155
|
486,1493,43,714,808,2642,1245,569,2508,81,155,1535,17,161,425,880,2091,500,317,533,1331,1040,360,142,469
|
0.676685832241666,-0.23609532189713084,2.734822878575379,0.351885919191322,0.2622351395530162,-1.6336795739285952,-0.07663805632366444,0.5428655840352268,-1.1088623151263601,2.248201202031891,1.7122602692585014,-0.25644127155135765,3.244826799017829,1.6992696820323683,0.8065146214158287,0.20754810800791113,-0.5954826549590951,0.6601814574178648,1.1001502232099265,0.6102896170952945,-0.11596206747168612,0.07722049678650203,0.9635315701724516,1.8147994633249862,0.7258267538427401
| 2,701
|
Subcutaneous nodule
| 12
| 18
| 2.053651
| 0.040009
|
Q9NZ08,P11802,P48735,P35222,P35637,Q13510,Q9Y2U8,Q9NSE4,Q8NBM4,P21912,P31749,P52732
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
360,606,329,73,364,119,806,403,738,314,636,676
|
1310,1075,606,314,636,73,364,329,812,676,1219,1081,119,1161,738,403,360,806
|
-0.11596206747168612,0.03925969392486323,0.49160405626708076,1.1001502232099265,0.4570917855835725,2.3276237027439657,0.9480828206502808,1.0550869617499012,0.2622351395530162,0.4048059034205665,-0.05710757719101301,0.03925969392486323,1.951920624080694,-0.01830586786658518,0.3341023914526849,0.8542183112675076,0.9635315701724516,0.28031310881637544
| 2,701
|
Oxidoreductase activity acting on the ch ch group of donors
| 11
| 28
| 2.053083
| 0.040065
|
O15254,Q15067,Q15392,Q9UBM7,Q9BY49,Q9NZ01,Q14739,Q6NUM9,Q7KZN9,Q9H7Z7,P21912
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
224,259,131,36,99,6,53,151,152,347,314
|
224,620,1495,2381,2546,314,1570,363,2397,1098,812,455,814,53,2565,259,131,151,1293,152,689,2686,2487,99,347,726,6,36
|
1.3891595529580087,0.47438206198749655,-0.23609532189713084,-0.8915779896099613,-1.183730197015092,1.1001502232099265,-0.27688196692354466,0.9480828206502808,-0.9151995911546438,0.02015513431309902,0.2622351395530162,0.742084510223003,0.2622351395530162,2.5574259051028014,-1.2089703136081216,1.2901855033977274,1.8901336133115505,1.7509988621945363,-0.09625596283480581,1.7381246312443195,0.38723710682081225,-2.6282476572158546,-1.0596452754232697,2.0966864062402033,1.0095506891404633,0.351885919191322,3.953135916812116,2.8057811853844417
| 2,701
|
Subsets and Splits
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