term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Regulation of mitochondrion organization
| 14
| 36
| 2.331249
| 0.01974
|
O75832,Q96A26,Q709C8,Q9NUQ9,Q9H3K2,Q9Y6C9,Q99536,O60313,P30536,P02786,O14737,P21796,P05141,P31749
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
190,166,363,139,303,273,339,239,114,333,242,23,274,409
|
447,242,239,190,1036,333,1843,274,1344,794,1248,23,2524,1440,114,409,2102,532,1569,363,1463,1017,2149,691,166,648,877,2593,339,2116,303,723,2192,139,591,273
|
0.6473133664185765,1.1140084276296076,1.1310694730368478,1.3741556701287698,0.1112864967658255,0.8438063884694104,-0.36473682773465654,1.0092219778652174,-0.06526800225829026,0.27807073501123514,-0.01377469592003253,3.300030759770216,-1.1321541889327764,-0.1176342396375531,1.9115709631930478,0.7077496739843829,-0.540732380985242,0.5435848808587928,-0.17089694126863775,0.8056207329272186,-0.1176342396375531,0.13569066148578596,-0.5710083209352036,0.36931090448637094,1.5528345987170111,0.4138804266239855,0.2313650943574053,-1.353903802647287,0.8438063884694104,-0.540732380985242,0.9369680850132093,0.3467667149096307,-0.6015642502581877,1.7057182117315222,0.47946851200506696,1.026980616676179
| 2,702
|
Endocytic vesicle
| 23
| 70
| 2.318651
| 0.020414
|
P50995,Q93050,Q12846,P08670,Q14108,Q969Q5,Q5KU26,Q14C86,P10321,P20645,Q86Y82,P11279,Q8WTV0,P51790,Q9Y487,P02786,O14964,P11717,O00461,Q15334,P61421,Q15907,P42345
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
516,151,536,284,30,427,170,301,419,175,438,318,69,198,204,333,331,457,90,601,463,349,619
|
960,1708,2342,90,331,728,1284,2396,1340,1769,791,333,1548,1196,284,1243,759,419,1344,318,457,616,1809,175,1848,1850,1348,619,1163,516,1600,1078,1405,2104,198,2058,1500,928,2595,1125,463,2014,1127,1977,536,974,1782,865,30,867,301,601,349,977,170,942,438,69,2306,151,427,1266,1373,749,1278,751,204,2122,1583,2043
|
0.15989814001547026,-0.2802102847132027,-0.7910150544529415,2.1559035701841203,0.8438063884694104,0.3240467416918007,-0.03941367046144973,-0.8566010715319217,-0.06526800225829026,-0.308138168176809,0.27807073501123514,0.8438063884694104,-0.17089694126863775,0.011651732815977752,0.9913427102790784,-0.01377469592003253,0.3011488166696212,0.687750303214672,-0.06526800225829026,0.881460002398148,0.6268724257185203,0.4359099189969065,-0.33631253477906203,1.4651313202975424,-0.36473682773465654,-0.36473682773465654,-0.06526800225829026,0.4359099189969065,0.036868377335003144,0.5646389006836805,-0.19787205833249796,0.08668311743058034,-0.09134055376869563,-0.540732380985242,1.3273799247937976,-0.5107324113409443,-0.14415202790824028,0.18391141717841533,-1.392223197306997,0.06187795047934465,0.6268724257185203,-0.4810044712723359,0.06187795047934465,-0.4515446964616516,0.5435848808587928,0.15989814001547026,-0.308138168176809,0.2313650943574053,3.1093432588488037,0.2313650943574053,0.9369680850132093,0.45777194879673416,0.8247808034059452,0.15989814001547026,1.509380323825773,0.18391141717841533,0.6676054254045067,2.414518252119156,-0.7266710972825526,1.6374471135787276,0.687750303214672,-0.01377469592003253,-0.06526800225829026,0.3240467416918007,-0.01377469592003253,0.3240467416918007,1.3115908775571128,-0.540732380985242,-0.17089694126863775,-0.4810044712723359
| 2,702
|
Steroid biosynthesis
| 8
| 10
| 2.309805
| 0.020899
|
Q15800,P48449,P38571,P37268,Q9UBM7,Q15392,Q16850,Q14534
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
67,130,449,579,445,49,50,412
|
595,579,449,130,412,49,799,67,50,445
|
0.45777194879673416,0.47946851200506696,0.6473133664185765,1.7850921167036022,0.7077496739843829,2.71205420662372,0.27807073501123514,2.433875016635886,2.71205420662372,0.6676054254045067
| 2,702
|
Abnormality of the lymphatic system
| 34
| 121
| 2.309255
| 0.020929
|
P08236,Q13510,O15460,Q9NZ08,P07602,P54802,Q86Y56,P16278,P31749,P21964,Q14108,Q6NUQ1,Q9H9Y6,P21281,P15586,Q9UJS0,Q14739,P11802,Q15392,Q9H0U3,P10619,Q9Y3Z3,P10253,P38571,Q01844,O15118,Q96A33,P28070,O95202,P00813,Q9NZJ7,P10644,P61916,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
261,134,258,137,11,141,143,19,409,408,30,160,288,291,164,429,298,420,49,443,63,455,317,449,202,74,330,207,332,225,365,111,240,125
|
512,2463,2448,2197,1762,74,258,1339,2547,992,2199,2510,332,2398,1154,2319,225,1036,125,1114,2548,1843,1637,824,11,919,261,701,317,63,111,1882,1844,2265,1345,1677,420,2644,2004,164,19,1592,2322,291,502,408,1552,1848,207,617,2010,409,1349,2173,1646,1350,1888,449,1851,1493,2241,2174,2325,706,2175,762,1200,2299,1853,1683,1854,1256,141,2059,1975,2550,1500,240,202,768,1129,1085,934,2021,598,134,2138,30,298,1414,1510,49,2142,2638,1515,505,160,1172,1897,143,630,1525,2678,1420,330,876,1661,2477,1024,443,288,783,2163,137,365,2441,429,477,884,455,1332
|
0.5646389006836805,-0.9916536280362304,-0.957392920200188,-0.6324042683431318,-0.308138168176809,2.3553210205573603,1.0621410964140288,-0.06526800225829026,-1.2045569767363151,0.13569066148578596,-0.6324042683431318,-1.0964994453628252,0.8438063884694104,-0.8566010715319217,0.036868377335003144,-0.7586901436735312,1.1815848149569044,0.1112864967658255,1.8365297753474792,0.06187795047934465,-1.2045569767363151,-0.36473682773465654,-0.22508051495738804,0.254810254426627,3.503168251453378,0.18391141717841533,1.0621410964140288,0.3467667149096307,0.881460002398148,2.4530486238043636,1.9360399599594456,-0.3934145562501481,-0.36473682773465654,-0.6949533822984102,-0.06526800225829026,-0.25252550560044684,0.687750303214672,-1.9299894948150549,-0.4810044712723359,1.5528345987170111,3.3763606176597847,-0.19787205833249796,-0.7586901436735312,0.9733415184995973,0.5855369618145146,0.7077496739843829,-0.17089694126863775,-0.36473682773465654,1.2797111548412214,0.4359099189969065,-0.4810044712723359,0.7077496739843829,-0.06526800225829026,-0.6015642502581877,-0.22508051495738804,-0.06526800225829026,-0.3934145562501481,0.6473133664185765,-0.36473682773465654,-0.14415202790824028,-0.6635325569459647,-0.6015642502581877,-0.7586901436735312,0.3467667149096307,-0.6015642502581877,0.3011488166696212,0.011651732815977752,-0.7266710972825526,-0.36473682773465654,-0.25252550560044684,-0.36473682773465654,-0.01377469592003253,1.678647365092368,-0.5107324113409443,-0.4515446964616516,-1.2045569767363151,-0.14415202790824028,1.1310694730368478,1.3115908775571128,0.3011488166696212,0.06187795047934465,0.08668311743058034,0.18391141717841533,-0.4810044712723359,0.45777194879673416,1.7191369886638892,-0.5710083209352036,3.1093432588488037,0.9552170880450557,-0.09134055376869563,-0.14415202790824028,2.71205420662372,-0.5710083209352036,-1.7139948007237693,-0.14415202790824028,0.5855369618145146,1.581373621216261,0.036868377335003144,-0.3934145562501481,1.6649938710643004,0.4359099189969065,-0.14415202790824028,-2.5542477552427933,-0.09134055376869563,0.8626989686693847,0.2313650943574053,-0.22508051495738804,-0.9916536280362304,0.13569066148578596,0.6676054254045067,0.9913427102790784,0.3011488166696212,-0.5710083209352036,1.7191369886638892,0.8056207329272186,-0.9234673291200788,0.687750303214672,0.6268724257185203,0.2313650943574053,0.6473133664185765,-0.03941367046144973
| 2,702
|
Membrane organization
| 59
| 205
| 2.305956
| 0.021113
|
Q9NS69,Q8N1F7,O95721,P04083,Q96CP7,P05141,P17152,P45880,Q15629,Q9UQB8,Q53EZ4,P31749,Q15363,Q15070,P46379,Q5J8M3,Q9BZF1,Q9P0J0,Q13505,Q9H3K2,Q15392,Q9NX63,Q86Y82,O75844,P48739,O43760,Q13190,P84095,P08183,P51790,O00429,O15118,O95249,Q96A33,Q9BVK6,Q9BUR5,Q8N4V1,Q8WUH2,Q9Y512,P50897,O95202,O14964,Q9NQC3,Q9NVH1,Q6P1A2,Q9NZJ7,Q86XL3,O60313,P61916,O95487,P30536,P16615,Q9P2W9,P50402,O14737,Q8IWA4,P57088,P49755,Q9Y5J7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,389,384,395,280,274,276,26,29,31,287,409,37,167,168,426,428,171,46,303,49,311,438,57,314,65,452,450,197,198,447,74,200,330,205,340,79,338,343,82,332,331,88,355,227,365,107,239,240,359,114,369,116,243,242,373,248,378,254
|
1708,512,447,2463,1033,2197,242,331,560,1632,74,789,1234,728,1335,1035,1336,1337,65,499,239,890,1284,1338,1392,1340,700,2495,1341,57,614,758,1073,332,1394,200,1712,1589,359,384,1036,395,1843,1674,274,1434,1196,1920,197,1715,1118,1244,794,369,276,2205,1923,998,853,2524,1440,114,409,2558,1886,735,2211,856,2101,2102,2269,26,2662,168,1852,314,378,243,762,1163,82,1078,2104,198,1202,926,1854,1974,763,248,1562,1500,928,580,240,739,2275,450,1932,566,710,1977,536,1567,1933,1507,452,974,46,1210,865,2513,486,867,1048,2651,167,1362,601,37,49,1571,2142,29,2526,568,1013,1364,287,869,426,1260,1460,718,227,944,2680,1463,107,438,373,1017,2149,1939,389,79,1138,744,2633,1264,663,338,664,507,665,905,693,805,330,280,1266,908,1375,813,340,205,428,2117,303,1064,1272,88,589,2665,0,355,311,365,1381,558,171,1472,1835,116,2682,633,2431,1704,2292,1959,2165,910,751,725,31,1065,478,884,1032,1385,820,343,254,650,2447
|
-0.2802102847132027,0.5646389006836805,0.6473133664185765,-0.9916536280362304,0.1112864967658255,-0.6324042683431318,1.1140084276296076,0.8438063884694104,0.5010015722710037,-0.22508051495738804,2.3553210205573603,0.27807073501123514,-0.01377469592003253,0.3240467416918007,-0.06526800225829026,0.1112864967658255,-0.06526800225829026,-0.06526800225829026,2.4434845439398956,0.5855369618145146,1.1310694730368478,0.20773293514525631,-0.03941367046144973,-0.06526800225829026,-0.09134055376869563,-0.06526800225829026,0.3467667149096307,-1.0612014774574168,-0.06526800225829026,2.5094973738711897,0.4359099189969065,0.3011488166696212,0.08668311743058034,0.8438063884694104,-0.09134055376869563,1.3115908775571128,-0.2802102847132027,-0.19787205833249796,0.8056207329272186,0.74731846202068,0.1112864967658255,0.7276051859633127,-0.36473682773465654,-0.25252550560044684,1.0092219778652174,-0.1176342396375531,0.011651732815977752,-0.4223492971351874,1.3273799247937976,-0.2802102847132027,0.06187795047934465,-0.01377469592003253,0.27807073501123514,0.7863246738934979,1.0092219778652174,-0.6324042683431318,-0.4223492971351874,0.13569066148578596,0.2313650943574053,-1.1321541889327764,-0.1176342396375531,1.9115709631930478,0.7077496739843829,-1.241316825230039,-0.3934145562501481,0.3240467416918007,-0.6324042683431318,0.2313650943574053,-0.540732380985242,-0.540732380985242,-0.6949533822984102,3.2819030749164693,-2.2060868946246557,1.5239522688610696,-0.36473682773465654,0.9000909263071639,0.7668911001385372,1.1140084276296076,0.3011488166696212,0.036868377335003144,2.2632150164335987,0.08668311743058034,-0.540732380985242,1.3273799247937976,0.011651732815977752,0.18391141717841533,-0.36473682773465654,-0.4515446964616516,0.3011488166696212,1.0968341446394454,-0.17089694126863775,-0.14415202790824028,0.18391141717841533,0.47946851200506696,1.1310694730368478,0.3240467416918007,-0.6949533822984102,0.6473133664185765,-0.4223492971351874,0.5010015722710037,0.3467667149096307,-0.4515446964616516,0.5435848808587928,-0.17089694126863775,-0.4223492971351874,-0.14415202790824028,0.6473133664185765,0.15989814001547026,2.753410498029949,0.011651732815977752,0.2313650943574053,-1.0964994453628252,0.6062808758329494,0.2313650943574053,0.1112864967658255,-2.0198857548091578,1.538436752547887,-0.06526800225829026,0.45777194879673416,2.9694470635904917,2.71205420662372,-0.17089694126863775,-0.5710083209352036,3.1293985059553213,-1.1321541889327764,0.5010015722710037,0.13569066148578596,-0.06526800225829026,0.9913427102790784,0.2313650943574053,0.687750303214672,-0.01377469592003253,-0.1176342396375531,0.3467667149096307,1.1815848149569044,0.18391141717841533,-3.0494230058693037,-0.1176342396375531,2.0078769667953464,0.6676054254045067,0.7863246738934979,0.13569066148578596,-0.5710083209352036,-0.4223492971351874,0.74731846202068,2.3250705886421623,0.06187795047934465,0.3240467416918007,-1.6722256933603648,-0.01377469592003253,0.39168144268614885,0.8438063884694104,0.39168144268614885,0.5855369618145146,0.39168144268614885,0.20773293514525631,0.36931090448637094,0.27807073501123514,0.8626989686693847,1.0092219778652174,-0.01377469592003253,0.20773293514525631,-0.06526800225829026,0.27807073501123514,0.8438063884694104,1.2957016226393265,0.687750303214672,-0.540732380985242,0.9369680850132093,0.1112864967658255,-0.01377469592003253,2.188669927046933,0.47946851200506696,-2.2060868946246557,4.4345567444728164,0.8247808034059452,0.9185931557162074,0.8056207329272186,-0.06526800225829026,0.5223730615720535,1.509380323825773,-0.1176342396375531,-0.33631253477906203,1.8992357988485726,-3.0494230058693037,0.4359099189969065,-0.8898717216903321,-0.25252550560044684,-0.6949533822984102,-0.4223492971351874,-0.5710083209352036,0.20773293514525631,0.3240467416918007,0.3467667149096307,3.1093432588488037,0.1112864967658255,0.6268724257185203,0.2313650943574053,0.13569066148578596,-0.06526800225829026,0.27807073501123514,0.8438063884694104,1.0795454359625347,0.4138804266239855,-0.9234673291200788
| 2,702
|
mitochondria
| 6
| 10
| 2.30074
| 0.021406
|
Q9Y277,Q15388,Q8IWA4,P21796,P45880,Q9NVH1
|
Localization
|
OpenCell Localization
|
opencell_localization
|
237,413,373,23,26,355
|
758,23,26,1736,413,373,427,589,355,237
|
0.3011488166696212,3.300030759770216,3.2819030749164693,-0.2802102847132027,0.7077496739843829,0.7863246738934979,0.687750303214672,0.47946851200506696,0.8247808034059452,1.148018452189637
| 2,702
|
membrane traffic protein
| 17
| 55
| 2.300646
| 0.021412
|
Q12907,P40855,Q8WUX9,Q13432,Q709C8,O00203,O00429,Q9NX40,P20645,O60313,Q9UPT5,P43307,Q8N2H4,P11717,A6NIH7,Q00765,Q96PC5
|
Functions
|
Panther Protein class
|
panther_protein_class
|
221,226,507,5,363,512,447,356,175,239,545,53,117,457,25,566,253
|
25,512,447,560,1336,1236,239,1338,1999,1769,791,457,175,895,1722,226,2350,53,1852,1648,1163,622,1974,2559,2014,566,1820,2220,221,5,1260,836,363,2253,117,1693,664,507,693,1266,253,877,908,780,749,2311,1026,1953,356,1381,1835,545,1533,1581,1385
|
3.2940101477528185,0.5646389006836805,0.6473133664185765,0.5010015722710037,-0.06526800225829026,-0.01377469592003253,1.1310694730368478,-0.06526800225829026,-0.4810044712723359,-0.308138168176809,0.27807073501123514,0.6268724257185203,1.4651313202975424,0.20773293514525631,-0.2802102847132027,1.1815848149569044,-0.7910150544529415,2.6001584197679355,-0.36473682773465654,-0.22508051495738804,0.036868377335003144,0.4359099189969065,-0.4515446964616516,-1.241316825230039,-0.4810044712723359,0.5010015722710037,-0.33631253477906203,-0.6324042683431318,1.1982044600111101,3.8520371556872264,-0.01377469592003253,0.254810254426627,0.8056207329272186,-0.6635325569459647,1.8743612216621832,-0.25252550560044684,0.39168144268614885,0.5855369618145146,0.36931090448637094,-0.01377469592003253,1.0795454359625347,0.2313650943574053,0.20773293514525631,0.3011488166696212,0.3240467416918007,-0.7266710972825526,0.13569066148578596,-0.4223492971351874,0.8247808034059452,-0.06526800225829026,-0.33631253477906203,0.5435848808587928,-0.14415202790824028,-0.17089694126863775,-0.06526800225829026
| 2,702
|
Organic acid transmembrane transport
| 12
| 29
| 2.3
| 0.021448
|
Q9UJS0,P08183,Q9UBX3,P23786,Q96NB2,Q9BQT8,Q9H2H9,P49768,Q9Y289,O43772,Q9H2D1,P31749
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
429,197,103,169,473,120,210,397,184,56,60,409
|
56,594,1238,1112,2201,197,1435,1882,169,617,409,2208,2558,856,397,1498,835,940,2614,473,492,120,60,210,1181,103,429,184,885
|
2.5187525853416863,0.45777194879673416,-0.01377469592003253,0.06187795047934465,-0.6324042683431318,1.3273799247937976,-0.1176342396375531,-0.3934145562501481,1.509380323825773,0.4359099189969065,0.7077496739843829,-0.6324042683431318,-1.241316825230039,0.2313650943574053,0.7276051859633127,-0.14415202790824028,0.254810254426627,0.18391141717841533,-1.5096459874254489,0.6268724257185203,0.6062808758329494,1.8743612216621832,2.4814715373825837,1.2797111548412214,0.036868377335003144,2.088833108363494,0.687750303214672,1.404856290131458,0.2313650943574053
| 2,702
|
Carboxylic acid transport
| 13
| 30
| 2.297239
| 0.021605
|
Q9UJS0,Q96QD8,Q9UBX3,Q9NZJ7,P07602,Q96NB2,Q9BQT8,O15439,P04083,Q9H2H9,P49768,Q9Y289,Q9H2D1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
429,492,103,365,11,473,120,479,395,210,397,184,60
|
479,594,1238,1112,395,2201,11,1435,2004,502,617,2558,856,397,1498,835,940,2025,2614,473,492,120,60,210,1181,365,103,429,184,885
|
0.6062808758329494,0.45777194879673416,-0.01377469592003253,0.06187795047934465,0.7276051859633127,-0.6324042683431318,3.503168251453378,-0.1176342396375531,-0.4810044712723359,0.5855369618145146,0.4359099189969065,-1.241316825230039,0.2313650943574053,0.7276051859633127,-0.14415202790824028,0.254810254426627,0.18391141717841533,-0.4810044712723359,-1.5096459874254489,0.6268724257185203,0.6062808758329494,1.8743612216621832,2.4814715373825837,1.2797111548412214,0.036868377335003144,0.8056207329272186,2.088833108363494,0.687750303214672,1.404856290131458,0.2313650943574053
| 2,702
|
Metal ion transport
| 30
| 87
| 2.29395
| 0.021793
|
Q02790,Q9Y376,Q9HD20,P62258,P49768,P21796,P42858,P31749,P61201,Q9Y6M7,Q9H0U3,Q9UJZ1,Q9Y289,O75844,Q8IWX8,O15173,O00429,Q9BPX6,Q8N4V1,P62942,Q9H2H9,P02786,O95202,Q15907,Q96QD8,Q16795,Q8NEW0,P16615,P30536,P78417
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
520,392,136,400,397,23,532,409,423,305,443,446,184,57,187,70,447,474,79,83,210,333,332,349,492,488,109,369,114,249
|
447,1762,70,848,2449,1286,757,2600,57,332,333,2511,615,1674,2201,1434,1920,1435,1844,1677,2003,369,1245,2557,531,2051,23,680,1680,1720,114,1294,409,1348,2054,532,1852,1444,397,1163,1164,1816,423,580,400,83,249,1932,1127,520,712,863,1567,1782,1654,2581,349,2526,488,1364,187,2571,79,691,109,665,804,2544,1371,1221,492,474,779,443,210,1181,136,2441,2431,446,1704,1187,1879,184,392,820,305
|
0.6473133664185765,-0.308138168176809,2.404770322309479,0.2313650943574053,-0.957392920200188,-0.03941367046144973,0.3011488166696212,-1.4309487853394973,2.5094973738711897,0.8438063884694104,0.8438063884694104,-1.0964994453628252,0.4359099189969065,-0.25252550560044684,-0.6324042683431318,-0.1176342396375531,-0.4223492971351874,-0.1176342396375531,-0.36473682773465654,-0.25252550560044684,-0.4810044712723359,0.7863246738934979,-0.01377469592003253,-1.241316825230039,0.5435848808587928,-0.5107324113409443,3.300030759770216,0.36931090448637094,-0.25252550560044684,-0.2802102847132027,1.9115709631930478,-0.03941367046144973,0.7077496739843829,-0.06526800225829026,-0.5107324113409443,0.5435848808587928,-0.36473682773465654,-0.1176342396375531,0.7276051859633127,0.036868377335003144,0.036868377335003144,-0.33631253477906203,0.687750303214672,0.47946851200506696,0.7276051859633127,2.2632150164335987,1.0968341446394454,-0.4223492971351874,0.06187795047934465,0.5646389006836805,0.3467667149096307,0.2313650943574053,-0.17089694126863775,-0.308138168176809,-0.22508051495738804,-1.315983932120922,0.8247808034059452,-1.1321541889327764,0.6062808758329494,-0.06526800225829026,1.3895536705247618,-1.2784570650664284,2.3250705886421623,0.36931090448637094,1.9602443238318379,0.39168144268614885,0.27807073501123514,-1.1681714201941449,-0.06526800225829026,0.011651732815977752,0.6062808758329494,0.6268724257185203,0.3011488166696212,0.6676054254045067,1.2797111548412214,0.036868377335003144,1.7191369886638892,-0.9234673291200788,-0.8898717216903321,0.6676054254045067,-0.25252550560044684,0.036868377335003144,-0.36473682773465654,1.404856290131458,0.74731846202068,0.27807073501123514,0.9369680850132093
| 2,702
|
Metallopeptidase activity
| 8
| 38
| 2.292437
| 0.02188
|
P42892,P52888,Q9NZ08,Q99797,O75844,Q9UIQ6,P55786,Q9BYT8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
95,73,137,108,57,58,157,92
|
1280,2262,1235,561,2600,57,562,1153,333,2411,2644,2413,1487,2467,1350,95,1448,73,157,1129,182,1212,2527,1089,1139,806,2475,1268,108,1374,92,1949,1992,2118,909,137,58,820
|
-0.03941367046144973,-0.6949533822984102,-0.01377469592003253,0.5010015722710037,-1.4309487853394973,2.5094973738711897,0.5010015722710037,0.036868377335003144,0.8438063884694104,-0.8898717216903321,-1.9299894948150549,-0.8898717216903321,-0.14415202790824028,-0.9916536280362304,-0.06526800225829026,2.1337776504182426,-0.1176342396375531,2.3949755597742,1.5955163931080725,0.06187795047934465,1.404856290131458,0.011651732815977752,-1.1321541889327764,0.08668311743058034,0.06187795047934465,0.27807073501123514,-0.9916536280362304,-0.01377469592003253,1.9960644529824567,-0.06526800225829026,2.1559035701841203,-0.4223492971351874,-0.4515446964616516,-0.540732380985242,0.20773293514525631,1.7191369886638892,2.500199007739095,0.27807073501123514
| 2,702
|
Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor
| 6
| 13
| 2.291014
| 0.021963
|
Q9BY49,Q14739,Q8N4Q0,Q15392,Q8N8N7,Q9H7Z7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
228,298,112,49,84,416
|
595,1490,706,1973,298,1360,49,112,84,228,416,2193,445
|
0.45777194879673416,-0.14415202790824028,0.3467667149096307,-0.4515446964616516,0.9552170880450557,-0.06526800225829026,2.71205420662372,1.9360399599594456,2.2632150164335987,1.1815848149569044,0.7077496739843829,-0.6015642502581877,0.6676054254045067
| 2,702
|
Primary mitochondrial disease
| 16
| 77
| 2.2891
| 0.022074
|
Q6DKK2,Q7KZN9,Q9UBX3,O95169,Q6P4A7,O43676,Q9Y2R0,Q70HW3,Q99797,Q9P0J0,Q9Y6M9,Q86Y39,O60313,P13073,O14949,Q9BQT8
|
Drugs and Diseases
|
Protein Atlas Disease involvement
|
protein_atlas_disease_involvement
|
163,195,103,259,41,44,77,14,108,171,178,234,239,269,149,120
|
1107,1067,149,44,2521,239,2667,822,1151,613,917,259,2345,290,407,1117,893,2002,794,269,2376,1249,1487,1717,1595,2535,1494,923,2057,2623,1254,2418,1503,2137,535,1412,488,869,2066,1822,2067,718,163,41,14,195,1899,234,775,2503,985,1372,108,2563,948,120,2337,842,1527,2564,1423,2160,574,1666,1028,171,2081,103,1994,1065,1473,77,788,1189,2195,1103,178
|
0.06187795047934465,0.08668311743058034,1.6374471135787276,2.777797385123894,-1.1321541889327764,1.1310694730368478,-2.302553966333245,0.254810254426627,0.036868377335003144,0.4359099189969065,0.18391141717841533,1.0621410964140288,-0.7910150544529415,0.9733415184995973,0.7077496739843829,0.06187795047934465,0.20773293514525631,-0.4810044712723359,0.27807073501123514,1.026980616676179,-0.8236504561955251,-0.01377469592003253,-0.14415202790824028,-0.2802102847132027,-0.19787205833249796,-1.1681714201941449,-0.14415202790824028,0.18391141717841533,-0.5107324113409443,-1.54963172247134,-0.01377469592003253,-0.8898717216903321,-0.14415202790824028,-0.5710083209352036,0.5435848808587928,-0.09134055376869563,0.6062808758329494,0.2313650943574053,-0.5107324113409443,-0.33631253477906203,-0.5107324113409443,0.3467667149096307,1.5671466206432492,2.8568664927325975,3.4216157303597954,1.3430697559709033,-0.3934145562501481,1.148018452189637,0.3011488166696212,-1.0612014774574168,0.15989814001547026,-0.06526800225829026,1.9960644529824567,-1.241316825230039,0.18391141717841533,1.8743612216621832,-0.7586901436735312,0.254810254426627,-0.14415202790824028,-1.241316825230039,-0.09134055376869563,-0.5710083209352036,0.5010015722710037,-0.22508051495738804,0.13569066148578596,1.509380323825773,-0.5107324113409443,2.088833108363494,-0.4515446964616516,0.1112864967658255,-0.1176342396375531,2.3452866902285905,0.3011488166696212,0.036868377335003144,-0.6015642502581877,0.08668311743058034,1.435179083173316
| 2,702
|
Cholesterol metabolism with bloch and kandutschrussell pathways
| 8
| 21
| 2.274509
| 0.022935
|
O00767,P48449,Q15800,Q14739,Q15392,Q16850,Q9BWD1,Q14534
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
405,130,67,298,49,50,245,412
|
405,1479,595,962,1289,963,2208,579,130,706,1819,2139,412,298,1982,49,799,67,50,245,445
|
0.7077496739843829,-0.14415202790824028,0.45777194879673416,0.15989814001547026,-0.03941367046144973,0.15989814001547026,-0.6324042683431318,0.47946851200506696,1.7850921167036022,0.3467667149096307,-0.33631253477906203,-0.5710083209352036,0.7077496739843829,0.9552170880450557,-0.4515446964616516,2.71205420662372,0.27807073501123514,2.433875016635886,2.71205420662372,1.1140084276296076,0.6676054254045067
| 2,702
|
Glycosyl compound metabolic process
| 8
| 26
| 2.256006
| 0.02407
|
P08236,P00813,Q13126,P36639,P49902,P06280,O60725,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
261,225,4,105,45,215,214,125
|
1587,1711,214,2319,1239,225,125,1114,2672,215,1770,261,2265,2321,2466,2373,1643,1347,105,45,972,1565,1305,4,281,881
|
-0.19787205833249796,-0.2802102847132027,1.247422490494699,-0.7586901436735312,-0.01377469592003253,1.1815848149569044,1.8365297753474792,0.06187795047934465,-2.451707377490616,1.247422490494699,-0.308138168176809,1.0621410964140288,-0.6949533822984102,-0.7586901436735312,-0.9916536280362304,-0.8236504561955251,-0.22508051495738804,-0.06526800225829026,2.0774498833224193,2.7697034335726243,0.15989814001547026,-0.17089694126863775,-0.03941367046144973,3.929611495114198,1.0092219778652174,0.2313650943574053
| 2,702
|
Neuromuscular process
| 10
| 25
| 2.254869
| 0.024142
|
P10253,P78417,O14773,P07196,P17900,Q7Z406,Q6Y7W6,O75844,P04062,Q8N0X7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
317,249,199,360,113,468,180,57,125,350
|
199,1765,1840,57,125,360,919,317,1345,113,1720,619,2269,1558,762,2242,249,486,601,180,468,1787,350,877,1320
|
1.3115908775571128,-0.308138168176809,-0.36473682773465654,2.5094973738711897,1.8365297753474792,0.8056207329272186,0.18391141717841533,0.881460002398148,-0.06526800225829026,1.9115709631930478,-0.2802102847132027,0.4359099189969065,-0.6949533822984102,-0.17089694126863775,0.3011488166696212,-0.6635325569459647,1.0968341446394454,0.6062808758329494,0.45777194879673416,1.4200644560622815,0.6268724257185203,-0.308138168176809,0.8247808034059452,0.2313650943574053,-0.03941367046144973
| 2,702
|
Reactive nitrogen species metabolic process
| 6
| 15
| 2.246993
| 0.02464
|
Q5VT66,P16435,O43169,P30536,Q08722,P06280
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,361,15,114,411,215
|
15,2435,1841,215,1196,850,361,680,114,409,1163,2275,411,131,875
|
3.3991465956104387,-0.9234673291200788,-0.36473682773465654,1.247422490494699,0.011651732815977752,0.2313650943574053,0.8056207329272186,0.36931090448637094,1.9115709631930478,0.7077496739843829,0.036868377335003144,-0.6949533822984102,0.7077496739843829,1.7850921167036022,0.2313650943574053
| 2,702
|
Abnormality of the spleen
| 29
| 101
| 2.245896
| 0.024711
|
P08236,Q13510,Q9NZ08,P07602,P54802,Q86Y56,P16278,P31749,P21964,Q14108,Q6NUQ1,P21281,P15586,Q9UJS0,Q14739,Q15392,Q9H0U3,P10619,Q9Y3Z3,P10253,P38571,O15118,Q96A33,P28070,O95202,P00813,Q9NZJ7,P61916,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
261,134,137,11,141,143,19,409,408,30,160,291,164,429,298,49,443,63,455,317,449,74,330,207,332,225,365,240,125
|
512,2463,2448,2197,1762,74,1339,2547,992,2510,332,2398,1154,2319,225,1036,125,1114,2548,1843,1637,824,11,919,261,701,317,63,1882,1844,2265,1345,1677,2644,2004,164,19,1592,2322,291,408,1552,1848,207,617,2010,409,1349,1350,1888,449,1851,1493,2241,2174,706,2175,1200,2299,1853,1683,1854,1256,141,1975,2550,240,768,1129,1085,2021,134,2138,30,298,1414,49,2142,2638,505,160,1172,143,630,1525,2678,1420,330,876,1661,2477,443,783,137,365,2441,429,477,884,455,1332
|
0.5646389006836805,-0.9916536280362304,-0.957392920200188,-0.6324042683431318,-0.308138168176809,2.3553210205573603,-0.06526800225829026,-1.2045569767363151,0.13569066148578596,-1.0964994453628252,0.8438063884694104,-0.8566010715319217,0.036868377335003144,-0.7586901436735312,1.1815848149569044,0.1112864967658255,1.8365297753474792,0.06187795047934465,-1.2045569767363151,-0.36473682773465654,-0.22508051495738804,0.254810254426627,3.503168251453378,0.18391141717841533,1.0621410964140288,0.3467667149096307,0.881460002398148,2.4530486238043636,-0.3934145562501481,-0.36473682773465654,-0.6949533822984102,-0.06526800225829026,-0.25252550560044684,-1.9299894948150549,-0.4810044712723359,1.5528345987170111,3.3763606176597847,-0.19787205833249796,-0.7586901436735312,0.9733415184995973,0.7077496739843829,-0.17089694126863775,-0.36473682773465654,1.2797111548412214,0.4359099189969065,-0.4810044712723359,0.7077496739843829,-0.06526800225829026,-0.06526800225829026,-0.3934145562501481,0.6473133664185765,-0.36473682773465654,-0.14415202790824028,-0.6635325569459647,-0.6015642502581877,0.3467667149096307,-0.6015642502581877,0.011651732815977752,-0.7266710972825526,-0.36473682773465654,-0.25252550560044684,-0.36473682773465654,-0.01377469592003253,1.678647365092368,-0.4515446964616516,-1.2045569767363151,1.1310694730368478,0.3011488166696212,0.06187795047934465,0.08668311743058034,-0.4810044712723359,1.7191369886638892,-0.5710083209352036,3.1093432588488037,0.9552170880450557,-0.09134055376869563,2.71205420662372,-0.5710083209352036,-1.7139948007237693,0.5855369618145146,1.581373621216261,0.036868377335003144,1.6649938710643004,0.4359099189969065,-0.14415202790824028,-2.5542477552427933,-0.09134055376869563,0.8626989686693847,0.2313650943574053,-0.22508051495738804,-0.9916536280362304,0.6676054254045067,0.3011488166696212,1.7191369886638892,0.8056207329272186,-0.9234673291200788,0.687750303214672,0.6268724257185203,0.2313650943574053,0.6473133664185765,-0.03941367046144973
| 2,702
|
Organic acid transmembrane transporter activity
| 9
| 21
| 2.236614
| 0.025312
|
P08183,Q9UJS0,Q96QD8,Q9UBX3,Q96NB2,Q9BQT8,Q9H2H9,Q9Y289,Q9H2D1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
197,429,492,103,473,120,210,184,60
|
479,594,1112,197,1435,2558,856,1498,835,940,2025,473,492,120,60,210,1181,103,429,184,885
|
0.6062808758329494,0.45777194879673416,0.06187795047934465,1.3273799247937976,-0.1176342396375531,-1.241316825230039,0.2313650943574053,-0.14415202790824028,0.254810254426627,0.18391141717841533,-0.4810044712723359,0.6268724257185203,0.6062808758329494,1.8743612216621832,2.4814715373825837,1.2797111548412214,0.036868377335003144,2.088833108363494,0.687750303214672,1.404856290131458,0.2313650943574053
| 2,702
|
Scrotal hypoplasia
| 9
| 18
| 2.235617
| 0.025377
|
Q9H9Y6,P46977,P07437,P16435,Q9UBM7,Q9NP72,Q6NUK1,Q15555,Q9BV10
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
288,285,325,361,445,607,414,186,353
|
994,325,361,1120,2174,285,1445,598,186,414,1522,1020,1219,353,288,607,445,1670
|
0.13569066148578596,0.8626989686693847,0.8056207329272186,0.06187795047934465,-0.6015642502581877,0.9913427102790784,-0.1176342396375531,0.45777194879673416,1.3895536705247618,0.7077496739843829,-0.14415202790824028,0.13569066148578596,0.011651732815977752,0.8247808034059452,0.9913427102790784,0.45777194879673416,0.6676054254045067,-0.22508051495738804
| 2,702
|
Vesicle membrane
| 65
| 212
| 2.229929
| 0.025752
|
Q99805,P24390,P42785,O00203,O95721,P07602,P62993,O15260,Q8IV08,P04083,P49768,Q08722,Q93050,O00264,Q12846,P42858,P20020,Q14108,P35613,O43924,Q15363,Q969Q5,Q15057,Q5KU26,P10321,P20645,P30519,Q9H0U3,Q9Y289,Q86Y82,Q9UIQ6,Q96JJ7,O43760,P10253,Q13190,Q9Y3B3,Q8WTV0,P51790,Q9Y487,P11279,Q07065,O15118,P84095,O00429,Q8N4V1,Q8NF37,P02786,O14964,P11717,O00461,P61421,Q92542,P42892,Q15907,Q9Y5X3,Q9Y5K8,Q709C8,Q9NZJ7,O95487,O15439,Q8TCT8,Q15904,Q8WUX9,P49755,Q9Y678
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
390,7,8,512,384,11,518,140,147,395,397,411,151,394,536,532,531,30,159,36,37,427,43,170,419,175,51,443,184,438,58,321,65,317,452,68,69,198,204,318,328,74,450,447,79,471,333,331,457,90,463,222,95,349,498,229,363,365,359,479,115,505,507,378,393
|
2643,960,1708,512,394,2584,447,90,1916,2197,528,331,1632,74,913,888,140,728,479,1335,1336,1236,65,1070,36,1284,1286,730,653,1338,1237,1287,1392,1340,1999,1840,1769,1073,1589,359,384,791,333,395,1548,2201,1434,11,1920,1243,759,2586,317,419,1244,1344,318,457,2349,531,702,2414,1809,175,1811,7,1848,1850,51,1294,1038,1442,159,1298,2101,2350,8,532,95,925,1445,1648,378,397,1163,1600,1078,1405,2104,198,1602,1727,2058,1854,763,928,2595,1125,2178,463,623,739,518,2275,2014,450,1127,2453,1977,328,2624,411,688,1820,2180,536,452,1782,740,1131,865,30,867,643,43,601,37,1571,2142,2065,505,349,1364,1687,170,2023,836,773,1611,363,2552,438,147,2253,79,744,471,2113,115,69,507,222,2255,647,151,1220,427,1266,321,1267,2034,877,2362,1373,390,1222,1374,2037,1875,780,443,749,2117,2311,1026,607,589,2078,365,1381,1472,2408,2120,1030,1835,1532,1426,590,2682,633,58,2531,2085,2292,1278,2165,910,1232,751,184,1427,1581,68,1385,204,229,2447,498,393,1538,1387,958
|
-1.8421278916189816,0.15989814001547026,-0.2802102847132027,0.5646389006836805,0.7276051859633127,-1.353903802647287,0.6473133664185765,2.1559035701841203,-0.4223492971351874,-0.6324042683431318,0.5435848808587928,0.8438063884694104,-0.22508051495738804,2.3553210205573603,0.18391141717841533,0.20773293514525631,1.692221906453172,0.3240467416918007,0.6062808758329494,-0.06526800225829026,-0.06526800225829026,-0.01377469592003253,2.4434845439398956,0.08668311743058034,2.9767096391211663,-0.03941367046144973,-0.03941367046144973,0.3240467416918007,0.39168144268614885,-0.06526800225829026,-0.01377469592003253,-0.03941367046144973,-0.09134055376869563,-0.06526800225829026,-0.4810044712723359,-0.36473682773465654,-0.308138168176809,0.08668311743058034,-0.19787205833249796,0.8056207329272186,0.74731846202068,0.27807073501123514,0.8438063884694104,0.7276051859633127,-0.17089694126863775,-0.6324042683431318,-0.1176342396375531,3.503168251453378,-0.4223492971351874,-0.01377469592003253,0.3011488166696212,-1.353903802647287,0.881460002398148,0.687750303214672,-0.01377469592003253,-0.06526800225829026,0.881460002398148,0.6268724257185203,-0.7910150544529415,0.5435848808587928,0.3467667149096307,-0.8898717216903321,-0.33631253477906203,1.4651313202975424,-0.33631253477906203,3.630300382746048,-0.36473682773465654,-0.36473682773465654,2.703674013197799,-0.03941367046144973,0.1112864967658255,-0.1176342396375531,1.581373621216261,-0.03941367046144973,-0.540732380985242,-0.7910150544529415,3.5552821414043194,0.5435848808587928,2.1337776504182426,0.18391141717841533,-0.1176342396375531,-0.22508051495738804,0.7668911001385372,0.7276051859633127,0.036868377335003144,-0.19787205833249796,0.08668311743058034,-0.09134055376869563,-0.540732380985242,1.3273799247937976,-0.19787205833249796,-0.2802102847132027,-0.5107324113409443,-0.36473682773465654,0.3011488166696212,0.18391141717841533,-1.392223197306997,0.06187795047934465,-0.6015642502581877,0.6268724257185203,0.4359099189969065,0.3240467416918007,0.5646389006836805,-0.6949533822984102,-0.4810044712723359,0.6473133664185765,0.06187795047934465,-0.957392920200188,-0.4515446964616516,0.8626989686693847,-1.54963172247134,0.7077496739843829,0.36931090448637094,-0.33631253477906203,-0.6015642502581877,0.5435848808587928,0.6473133664185765,-0.308138168176809,0.3240467416918007,0.06187795047934465,0.2313650943574053,3.1093432588488037,0.2313650943574053,0.4138804266239855,2.8098285602303847,0.45777194879673416,2.9694470635904917,-0.17089694126863775,-0.5710083209352036,-0.5107324113409443,0.5855369618145146,0.8247808034059452,-0.06526800225829026,-0.25252550560044684,1.509380323825773,-0.4810044712723359,0.254810254426627,0.3011488166696212,-0.19787205833249796,0.8056207329272186,-1.2045569767363151,0.6676054254045067,1.651260698795158,-0.6635325569459647,2.3250705886421623,0.3240467416918007,0.6268724257185203,-0.540732380985242,1.9115709631930478,2.414518252119156,0.5855369618145146,1.1982044600111101,-0.6635325569459647,0.4138804266239855,1.6374471135787276,0.011651732815977752,0.687750303214672,-0.01377469592003253,0.881460002398148,-0.01377469592003253,-0.4810044712723359,0.2313650943574053,-0.7910150544529415,-0.06526800225829026,0.74731846202068,0.011651732815977752,-0.06526800225829026,-0.4810044712723359,-0.36473682773465654,0.3011488166696212,0.6676054254045067,0.3240467416918007,-0.540732380985242,-0.7266710972825526,0.13569066148578596,0.45777194879673416,0.47946851200506696,-0.5107324113409443,0.8056207329272186,-0.06526800225829026,-0.1176342396375531,-0.8566010715319217,-0.540732380985242,0.13569066148578596,-0.33631253477906203,-0.14415202790824028,-0.09134055376869563,0.47946851200506696,-3.0494230058693037,0.4359099189969065,2.500199007739095,-1.1321541889327764,-0.5107324113409443,-0.6949533822984102,-0.01377469592003253,-0.5710083209352036,0.20773293514525631,0.011651732815977752,0.3240467416918007,1.404856290131458,-0.09134055376869563,-0.17089694126863775,2.424219700870432,-0.06526800225829026,1.3115908775571128,1.1815848149569044,-0.9234673291200788,0.6062808758329494,0.74731846202068,-0.14415202790824028,-0.06526800225829026,0.18391141717841533
| 2,702
|
Protein import
| 24
| 81
| 2.221058
| 0.026347
|
Q9NS69,Q99595,Q99623,Q8N1F7,P52292,P49768,Q15388,P31749,O95831,O15397,O95373,P06493,O14925,Q14978,Q9Y512,P52294,P55060,Q92973,P40855,O75381,Q8TEX9,O14737,P21359,P12270
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,1,525,389,398,397,413,409,290,176,563,578,206,467,343,461,462,375,226,345,118,242,502,501
|
612,1540,2125,242,206,176,674,1390,1071,345,1341,758,1433,563,290,891,1036,1843,578,1196,850,2450,1244,501,2050,2051,502,409,1886,1121,1925,1851,226,397,2013,1162,762,398,461,1891,462,763,796,1408,1042,930,1085,1507,934,1259,467,413,1686,2143,1784,1013,716,1213,1689,979,389,1176,118,1788,375,605,2562,1751,1,525,1094,1058,1904,1144,0,1145,2431,882,2084,343,754
|
0.4359099189969065,-0.17089694126863775,-0.5710083209352036,1.1140084276296076,1.2797111548412214,1.435179083173316,0.36931090448637094,-0.09134055376869563,0.08668311743058034,0.8247808034059452,-0.06526800225829026,0.3011488166696212,-0.1176342396375531,0.5010015722710037,0.9733415184995973,0.20773293514525631,0.1112864967658255,-0.36473682773465654,0.47946851200506696,0.011651732815977752,0.2313650943574053,-0.957392920200188,-0.01377469592003253,0.5855369618145146,-0.5107324113409443,-0.5107324113409443,0.5855369618145146,0.7077496739843829,-0.3934145562501481,0.06187795047934465,-0.4223492971351874,-0.36473682773465654,1.1815848149569044,0.7276051859633127,-0.4810044712723359,0.036868377335003144,0.3011488166696212,0.7276051859633127,0.6268724257185203,-0.3934145562501481,0.6268724257185203,0.3011488166696212,0.27807073501123514,-0.09134055376869563,0.1112864967658255,0.18391141717841533,0.08668311743058034,-0.14415202790824028,0.18391141717841533,-0.01377469592003253,0.6268724257185203,0.7077496739843829,-0.25252550560044684,-0.5710083209352036,-0.308138168176809,0.13569066148578596,0.3467667149096307,0.011651732815977752,-0.25252550560044684,0.15989814001547026,0.74731846202068,0.036868377335003144,1.8743612216621832,-0.308138168176809,0.7863246738934979,0.45777194879673416,-1.241316825230039,-0.2802102847132027,4.159262994962356,0.5646389006836805,0.08668311743058034,0.1112864967658255,-0.3934145562501481,0.06187795047934465,4.4345567444728164,0.06187795047934465,-0.8898717216903321,0.2313650943574053,-0.5107324113409443,0.8438063884694104,0.3240467416918007
| 2,702
|
Hallucinations
| 15
| 42
| 2.217256
| 0.026606
|
O75503,Q9BQE5,Q6DKK2,Q9UJS0,Q709C8,Q9NZJ7,P07602,P35637,O60313,P49768,Q6Y7W6,P50897,P04062,P21964,Q8N0X7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
406,34,163,429,363,365,11,270,239,397,180,82,125,408,350
|
2124,447,2448,1337,239,1287,406,891,125,11,2486,2375,1923,408,270,1350,532,682,397,82,2134,971,2380,927,1007,1781,1507,2387,163,180,363,350,1986,1219,877,2593,1946,34,2290,365,429,1065
|
-0.5710083209352036,0.6473133664185765,-0.957392920200188,-0.06526800225829026,1.1310694730368478,-0.03941367046144973,0.7077496739843829,0.20773293514525631,1.8365297753474792,3.503168251453378,-1.0262546953488343,-0.8236504561955251,-0.4223492971351874,0.7077496739843829,1.026980616676179,-0.06526800225829026,0.5435848808587928,0.36931090448637094,0.7276051859633127,2.2632150164335987,-0.5710083209352036,0.15989814001547026,-0.8236504561955251,0.18391141717841533,0.13569066148578596,-0.308138168176809,-0.14415202790824028,-0.8236504561955251,1.5671466206432492,1.4200644560622815,0.8056207329272186,0.8247808034059452,-0.4515446964616516,0.011651732815977752,0.2313650943574053,-1.353903802647287,-0.4223492971351874,3.0547069293922724,-0.6949533822984102,0.8056207329272186,0.687750303214672,0.1112864967658255
| 2,702
|
Purine nucleotide transmembrane transporter activity
| 7
| 10
| 2.214131
| 0.02682
|
P12236,O15439,Q8TB61,P05141,Q6NUK1,O43808,O00400
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
267,479,181,274,414,283,155
|
155,479,283,274,794,267,856,414,181,557
|
1.5955163931080725,0.6062808758329494,0.9913427102790784,1.0092219778652174,0.27807073501123514,1.044619903415622,0.2313650943574053,0.7077496739843829,1.4200644560622815,0.5223730615720535
| 2,702
|
Diminished movement
| 8
| 17
| 2.210664
| 0.027059
|
O95831,P42858,Q709C8,Q14203,Q2TAA5,P06753,Q6Y7W6,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
290,532,363,486,581,548,180,125
|
1287,290,125,548,794,532,621,1007,486,1607,581,180,363,877,1372,1751,1330
|
-0.03941367046144973,0.9733415184995973,1.8365297753474792,0.5223730615720535,0.27807073501123514,0.5435848808587928,0.4359099189969065,0.13569066148578596,0.6062808758329494,-0.19787205833249796,0.47946851200506696,1.4200644560622815,0.8056207329272186,0.2313650943574053,-0.06526800225829026,-0.2802102847132027,-0.03941367046144973
| 2,702
|
Mitochondrial carrier protein [IPR002067]
| 6
| 9
| 2.209951
| 0.027109
|
P12236,P05141,Q6NUK1,O43808,Q9BQT8,Q9HC21
|
Sequence
|
InterPro Family
|
interpro_family
|
267,274,414,283,120,323
|
283,594,274,794,267,414,120,323,429
|
0.9913427102790784,0.45777194879673416,1.0092219778652174,0.27807073501123514,1.044619903415622,0.7077496739843829,1.8743612216621832,0.881460002398148,0.687750303214672
| 2,702
|
vesicle coat protein
| 7
| 28
| 2.200982
| 0.027737
|
Q9Y3B3,Q15363,Q9BVK6,O95487,P53367,P49755,Q7Z7H5
|
Functions
|
Panther Protein class
|
panther_protein_class
|
68,37,205,359,247,378,191
|
1916,1073,1589,359,1243,759,1442,1445,378,247,1602,1727,2058,1854,623,1127,974,37,1571,2142,191,2255,205,1426,590,1331,68,393
|
-0.4223492971351874,0.08668311743058034,-0.19787205833249796,0.8056207329272186,-0.01377469592003253,0.3011488166696212,-0.1176342396375531,-0.1176342396375531,0.7668911001385372,1.0968341446394454,-0.19787205833249796,-0.2802102847132027,-0.5107324113409443,-0.36473682773465654,0.4359099189969065,0.06187795047934465,0.15989814001547026,2.9694470635904917,-0.17089694126863775,-0.5710083209352036,1.3741556701287698,-0.6635325569459647,1.2957016226393265,-0.09134055376869563,0.47946851200506696,-0.03941367046144973,2.424219700870432,0.74731846202068
| 2,702
|
Exocytic vesicle
| 14
| 31
| 2.190755
| 0.02847
|
Q15907,O43760,P11279,P51790,O00429,Q9BT78,Q14141,Q9BVK6,P49768,P50897,Q86Y82,Q12846,P61421,Q92542
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
349,65,318,198,447,493,233,205,397,82,438,536,463,222
|
447,913,728,65,1243,759,318,531,1809,1680,397,82,1078,2104,198,928,2595,463,536,974,233,1047,2421,601,349,438,222,1139,493,205,2116
|
0.6473133664185765,0.18391141717841533,0.3240467416918007,2.4434845439398956,-0.01377469592003253,0.3011488166696212,0.881460002398148,0.5435848808587928,-0.33631253477906203,-0.25252550560044684,0.7276051859633127,2.2632150164335987,0.08668311743058034,-0.540732380985242,1.3273799247937976,0.18391141717841533,-1.392223197306997,0.6268724257185203,0.5435848808587928,0.15989814001547026,1.148018452189637,0.1112864967658255,-0.8898717216903321,0.45777194879673416,0.8247808034059452,0.6676054254045067,1.1982044600111101,0.06187795047934465,0.6062808758329494,1.2957016226393265,-0.540732380985242
| 2,702
|
Translocation
| 9
| 45
| 2.181761
| 0.029127
|
Q9NS69,Q99595,O75381,Q8NFH4,O14925,Q12769,Q9Y5J7,Q9BTX1,Q15629
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
0,1,345,294,206,308,254,154,29
|
960,206,674,345,1341,501,1121,1925,2013,1162,1891,763,796,2559,580,1408,2015,308,29,1013,2184,716,1213,389,294,1176,874,2114,1788,1987,666,776,1751,1,154,1094,1058,1904,1756,0,609,1957,2084,254,650
|
0.15989814001547026,1.2797111548412214,0.36931090448637094,0.8247808034059452,-0.06526800225829026,0.5855369618145146,0.06187795047934465,-0.4223492971351874,-0.4810044712723359,0.036868377335003144,-0.3934145562501481,0.3011488166696212,0.27807073501123514,-1.241316825230039,0.47946851200506696,-0.09134055376869563,-0.4810044712723359,0.9185931557162074,3.1293985059553213,0.13569066148578596,-0.6015642502581877,0.3467667149096307,0.011651732815977752,0.74731846202068,0.9733415184995973,0.036868377335003144,0.2313650943574053,-0.540732380985242,-0.308138168176809,-0.4515446964616516,0.39168144268614885,0.3011488166696212,-0.2802102847132027,4.159262994962356,1.6095757189373043,0.08668311743058034,0.1112864967658255,-0.3934145562501481,-0.2802102847132027,4.4345567444728164,0.45777194879673416,-0.4223492971351874,-0.5107324113409443,1.0795454359625347,0.4138804266239855
| 2,702
|
Metalloprotease
| 8
| 35
| 2.179209
| 0.029316
|
P42892,P52888,Q9NZ08,Q99797,O75844,Q9UIQ6,P55786,Q9BYT8
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
95,73,137,108,57,58,157,92
|
1280,2262,1235,561,2600,57,1153,333,1808,2644,2413,1487,2467,2468,95,1448,73,157,1129,1047,2226,182,2527,1089,2231,1139,1790,2475,1268,108,92,909,137,58,820
|
-0.03941367046144973,-0.6949533822984102,-0.01377469592003253,0.5010015722710037,-1.4309487853394973,2.5094973738711897,0.036868377335003144,0.8438063884694104,-0.33631253477906203,-1.9299894948150549,-0.8898717216903321,-0.14415202790824028,-0.9916536280362304,-0.9916536280362304,2.1337776504182426,-0.1176342396375531,2.3949755597742,1.5955163931080725,0.06187795047934465,0.1112864967658255,-0.6324042683431318,1.404856290131458,-1.1321541889327764,0.08668311743058034,-0.6324042683431318,0.06187795047934465,-0.308138168176809,-0.9916536280362304,-0.01377469592003253,1.9960644529824567,2.1559035701841203,0.20773293514525631,1.7191369886638892,2.500199007739095,0.27807073501123514
| 2,702
|
Selective autophagy
| 9
| 28
| 2.177877
| 0.029415
|
Q9NS69,P04350,P54619,Q8N4H5,Q8IWA4,P21796,Q9BVA1,Q15388,P08670
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,300,435,52,373,23,380,413,284
|
914,730,758,891,300,1196,284,1244,1248,23,762,435,2380,1124,1564,464,2420,599,798,413,373,52,648,2593,670,380,0,1387
|
0.18391141717841533,0.3240467416918007,0.3011488166696212,0.20773293514525631,0.9369680850132093,0.011651732815977752,0.9913427102790784,-0.01377469592003253,-0.01377469592003253,3.300030759770216,0.3011488166696212,0.6676054254045067,-0.8236504561955251,0.06187795047934465,-0.17089694126863775,0.6268724257185203,-0.8898717216903321,0.45777194879673416,0.27807073501123514,0.7077496739843829,0.7863246738934979,2.617799486981324,0.4138804266239855,-1.353903802647287,0.39168144268614885,0.7668911001385372,4.4345567444728164,-0.06526800225829026
| 2,702
|
Ion channel transport
| 10
| 27
| 2.177755
| 0.029424
|
P21281,Q9Y5K8,P51790,Q9Y487,Q9HD20,P16615,Q15904,Q93050,Q9C0H2,P61421
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
291,229,198,204,136,369,505,151,59,463
|
615,1674,369,531,291,2127,680,1294,922,1721,198,1683,1816,463,1932,1893,1782,505,1364,744,151,1221,59,136,1799,204,229
|
0.4359099189969065,-0.25252550560044684,0.7863246738934979,0.5435848808587928,0.9733415184995973,-0.5710083209352036,0.36931090448637094,-0.03941367046144973,0.18391141717841533,-0.2802102847132027,1.3273799247937976,-0.25252550560044684,-0.33631253477906203,0.6268724257185203,-0.4223492971351874,-0.3934145562501481,-0.308138168176809,0.5855369618145146,-0.06526800225829026,0.3240467416918007,1.6374471135787276,0.011651732815977752,2.4814715373825837,1.7191369886638892,-0.308138168176809,1.3115908775571128,1.1815848149569044
| 2,702
|
Glycerophospholipid biosynthesis
| 10
| 27
| 2.17463
| 0.029658
|
Q6P1A2,Q9BZF1,Q9NQZ5,P35790,Q9NPH0,O95674,Q8IV08,Q92604,P48739,P48651
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
227,428,40,138,203,368,147,279,314,410
|
1034,789,1237,368,1248,138,2129,2213,410,314,1650,1564,869,227,870,147,2571,1018,471,279,1374,2188,428,203,40,1906,591
|
0.1112864967658255,0.27807073501123514,-0.01377469592003253,0.7863246738934979,-0.01377469592003253,1.7057182117315222,-0.5710083209352036,-0.6324042683431318,0.7077496739843829,0.9000909263071639,-0.22508051495738804,-0.17089694126863775,0.2313650943574053,1.1815848149569044,0.2313650943574053,1.651260698795158,-1.2784570650664284,0.13569066148578596,0.6268724257185203,1.0092219778652174,-0.06526800225829026,-0.6015642502581877,0.687750303214672,1.3115908775571128,2.9401004245140965,-0.3934145562501481,0.47946851200506696
| 2,702
|
Protein transport
| 71
| 212
| 2.172655
| 0.029806
|
Q9NS69,Q99595,Q9Y5J9,Q8N1F7,A0AVF1,Q13432,O95070,P24390,O00203,Q9HD20,O95721,O43823,Q8WUM4,Q92621,P52292,Q9UPT5,Q9H089,A6NIH7,Q9BTX1,Q15388,O94832,Q15629,Q6NUQ1,O14828,Q15363,Q8NFH4,Q969Q5,Q641Q2,P20290,Q13505,Q9UGP8,O15397,Q8N4H5,Q12769,O95373,Q86Y82,Q7Z7H5,Q9UBQ0,Q9NR31,Q9Y3B3,Q8IYI6,O95249,Q9BVK6,O14925,P61619,Q8WUH2,Q9BUN8,Q9P2E9,Q9NP72,Q96P70,O14964,P52294,P55060,Q12907,Q15907,Q9Y5X3,Q8WUX9,P61923,O75381,P51572,O95487,Q9P2W9,Q8N2H4,Q8TEX9,Q92973,O00410,Q92783,P49755,P12270,Q9Y5J7,Q9Y678
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
0,1,650,389,132,5,500,7,512,136,384,513,664,666,398,545,541,25,154,413,654,29,160,528,37,294,427,554,550,46,575,176,52,308,563,438,191,590,589,68,586,200,205,206,580,338,209,609,607,605,331,461,462,221,349,498,507,623,345,622,359,116,117,118,375,612,647,378,501,254,393
|
132,25,960,1708,2342,512,612,1540,2125,1916,2197,528,206,331,1069,1632,913,888,176,1335,1586,674,1336,848,1236,513,1284,1390,653,1338,1287,345,1340,700,1999,1341,1482,654,1769,1073,500,1394,200,563,1589,359,384,791,891,501,920,550,2414,1809,7,1442,1121,2209,1925,2350,1852,1445,1648,736,378,2013,1162,762,1600,1078,1405,2104,622,398,461,1891,1602,1727,2058,1854,1974,462,763,796,2559,1040,928,686,2595,1125,580,623,1408,739,1042,2014,2015,1208,1820,2220,308,221,2222,5,46,1131,1259,37,413,1571,2142,29,349,1013,1687,1260,2184,716,836,554,160,1213,191,438,586,2253,389,117,52,2030,294,1176,1693,874,2114,118,981,338,1788,664,507,1825,1987,905,2255,666,647,375,1220,805,427,1266,776,1661,1267,605,877,1751,1,908,1222,154,209,205,1094,1058,1904,2310,780,2365,541,2117,2311,1226,1182,1064,136,1026,607,589,1756,0,2391,1185,2078,1381,2408,609,116,1426,590,1957,575,882,2530,2084,2085,1278,2165,1232,545,1581,1331,68,1537,1385,254,650,754,2447,498,393
|
1.7324789362764448,3.2940101477528185,0.15989814001547026,-0.2802102847132027,-0.7910150544529415,0.5646389006836805,0.4359099189969065,-0.17089694126863775,-0.5710083209352036,-0.4223492971351874,-0.6324042683431318,0.5435848808587928,1.2797111548412214,0.8438063884694104,0.08668311743058034,-0.22508051495738804,0.18391141717841533,0.20773293514525631,1.435179083173316,-0.06526800225829026,-0.19787205833249796,0.36931090448637094,-0.06526800225829026,0.2313650943574053,-0.01377469592003253,0.5646389006836805,-0.03941367046144973,-0.09134055376869563,0.39168144268614885,-0.06526800225829026,-0.03941367046144973,0.8247808034059452,-0.06526800225829026,0.3467667149096307,-0.4810044712723359,-0.06526800225829026,-0.14415202790824028,0.39168144268614885,-0.308138168176809,0.08668311743058034,0.5855369618145146,-0.09134055376869563,1.3115908775571128,0.5010015722710037,-0.19787205833249796,0.8056207329272186,0.74731846202068,0.27807073501123514,0.20773293514525631,0.5855369618145146,0.18391141717841533,0.5223730615720535,-0.8898717216903321,-0.33631253477906203,3.630300382746048,-0.1176342396375531,0.06187795047934465,-0.6324042683431318,-0.4223492971351874,-0.7910150544529415,-0.36473682773465654,-0.1176342396375531,-0.22508051495738804,0.3240467416918007,0.7668911001385372,-0.4810044712723359,0.036868377335003144,0.3011488166696212,-0.19787205833249796,0.08668311743058034,-0.09134055376869563,-0.540732380985242,0.4359099189969065,0.7276051859633127,0.6268724257185203,-0.3934145562501481,-0.19787205833249796,-0.2802102847132027,-0.5107324113409443,-0.36473682773465654,-0.4515446964616516,0.6268724257185203,0.3011488166696212,0.27807073501123514,-1.241316825230039,0.1112864967658255,0.18391141717841533,0.36931090448637094,-1.392223197306997,0.06187795047934465,0.47946851200506696,0.4359099189969065,-0.09134055376869563,0.3240467416918007,0.1112864967658255,-0.4810044712723359,-0.4810044712723359,0.011651732815977752,-0.33631253477906203,-0.6324042683431318,0.9185931557162074,1.1982044600111101,-0.6324042683431318,3.8520371556872264,2.753410498029949,0.06187795047934465,-0.01377469592003253,2.9694470635904917,0.7077496739843829,-0.17089694126863775,-0.5710083209352036,3.1293985059553213,0.8247808034059452,0.13569066148578596,-0.25252550560044684,-0.01377469592003253,-0.6015642502581877,0.3467667149096307,0.254810254426627,0.5223730615720535,1.581373621216261,0.011651732815977752,1.3741556701287698,0.6676054254045067,0.47946851200506696,-0.6635325569459647,0.74731846202068,1.8743612216621832,2.617799486981324,-0.4810044712723359,0.9733415184995973,0.036868377335003144,-0.25252550560044684,0.2313650943574053,-0.540732380985242,1.8743612216621832,0.15989814001547026,0.8438063884694104,-0.308138168176809,0.39168144268614885,0.5855369618145146,-0.33631253477906203,-0.4515446964616516,0.20773293514525631,-0.6635325569459647,0.39168144268614885,0.4138804266239855,0.7863246738934979,0.011651732815977752,0.27807073501123514,0.687750303214672,-0.01377469592003253,0.3011488166696212,-0.22508051495738804,-0.01377469592003253,0.45777194879673416,0.2313650943574053,-0.2802102847132027,4.159262994962356,0.20773293514525631,0.011651732815977752,1.6095757189373043,1.2797111548412214,1.2957016226393265,0.08668311743058034,0.1112864967658255,-0.3934145562501481,-0.7266710972825526,0.3011488166696212,-0.7910150544529415,0.5435848808587928,-0.540732380985242,-0.7266710972825526,0.011651732815977752,0.036868377335003144,0.1112864967658255,1.7191369886638892,0.13569066148578596,0.45777194879673416,0.47946851200506696,-0.2802102847132027,4.4345567444728164,-0.8236504561955251,0.036868377335003144,-0.5107324113409443,-0.06526800225829026,-0.8566010715319217,0.45777194879673416,1.8992357988485726,-0.09134055376869563,0.47946851200506696,-0.4223492971351874,0.5010015722710037,0.2313650943574053,-1.1321541889327764,-0.5107324113409443,-0.5107324113409443,-0.01377469592003253,-0.5710083209352036,0.011651732815977752,0.5435848808587928,-0.17089694126863775,-0.03941367046144973,2.424219700870432,-0.14415202790824028,-0.06526800225829026,1.0795454359625347,0.4138804266239855,0.3240467416918007,-0.9234673291200788,0.6062808758329494,0.74731846202068
| 2,702
|
Proton transmembrane transporter activity
| 13
| 34
| 2.168843
| 0.030095
|
O75964,P21281,Q7KZN9,Q9Y5K8,P51790,Q9Y487,P24539,Q96ES6,P13073,Q93050,P05141,O00400,Q9UDW1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
94,291,195,229,198,204,296,76,269,151,274,155,98
|
155,1673,94,332,407,274,1115,893,1639,794,269,1249,291,2127,296,1717,2468,968,922,1721,2378,198,2688,657,463,933,936,195,151,76,98,1799,204,229
|
1.5955163931080725,-0.25252550560044684,2.1337776504182426,0.8438063884694104,0.7077496739843829,1.0092219778652174,0.06187795047934465,0.20773293514525631,-0.22508051495738804,0.27807073501123514,1.026980616676179,-0.01377469592003253,0.9733415184995973,-0.5710083209352036,0.9552170880450557,-0.2802102847132027,-0.9916536280362304,0.15989814001547026,0.18391141717841533,-0.2802102847132027,-0.8236504561955251,1.3273799247937976,-4.476245528731529,0.39168144268614885,0.6268724257185203,0.18391141717841533,0.18391141717841533,1.3430697559709033,1.6374471135787276,2.3452866902285905,2.1337776504182426,-0.308138168176809,1.3115908775571128,1.1815848149569044
| 2,702
|
Autophagy
| 18
| 38
| 2.168649
| 0.030109
|
Q9NS69,Q6IAA8,Q13885,Q8WUX9,O94826,O60664,Q96HS1,P04350,P54619,Q9BUF5,P42345,Q8N4H5,Q8IWA4,P21796,Q9BVA1,Q15388,P08670,P68371
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,773,599,507,758,730,648,300,435,670,619,52,373,23,380,413,284,464
|
914,1336,730,758,891,300,1196,850,284,1244,1248,23,619,762,435,2380,1040,1124,1564,464,2420,599,798,413,773,373,52,507,648,2593,1373,1222,670,380,0,2391,1385,1387
|
0.18391141717841533,-0.06526800225829026,0.3240467416918007,0.3011488166696212,0.20773293514525631,0.9369680850132093,0.011651732815977752,0.2313650943574053,0.9913427102790784,-0.01377469592003253,-0.01377469592003253,3.300030759770216,0.4359099189969065,0.3011488166696212,0.6676054254045067,-0.8236504561955251,0.1112864967658255,0.06187795047934465,-0.17089694126863775,0.6268724257185203,-0.8898717216903321,0.45777194879673416,0.27807073501123514,0.7077496739843829,0.3011488166696212,0.7863246738934979,2.617799486981324,0.5855369618145146,0.4138804266239855,-1.353903802647287,-0.06526800225829026,0.011651732815977752,0.39168144268614885,0.7668911001385372,4.4345567444728164,-0.8236504561955251,-0.06526800225829026,-0.06526800225829026
| 2,702
|
Lipid droplet
| 7
| 27
| 2.165365
| 0.03036
|
O43760,P48449,Q8NBX0,Q07065,Q9H6V9,Q99720,Q01105
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
65,130,102,328,81,22,216
|
1586,65,1479,730,962,2435,1842,1434,130,1600,1078,622,2380,216,328,799,350,102,471,905,1056,22,81,697,607,2433,2166
|
-0.19787205833249796,2.4434845439398956,-0.14415202790824028,0.3240467416918007,0.15989814001547026,-0.9234673291200788,-0.36473682773465654,-0.1176342396375531,1.7850921167036022,-0.19787205833249796,0.08668311743058034,0.4359099189969065,-0.8236504561955251,1.247422490494699,0.8626989686693847,0.27807073501123514,0.8247808034059452,2.1114220884425734,0.6268724257185203,0.20773293514525631,0.1112864967658255,3.3179623931981417,2.2840378914077024,0.36931090448637094,0.45777194879673416,-0.8898717216903321,-0.5710083209352036
| 2,702
|
Neuron projection terminus
| 8
| 14
| 2.161019
| 0.030694
|
P51790,Q13641,O75150,Q14141,Q7L576,P61421,Q9UQB8,Q05682
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
198,521,358,233,604,463,31,451
|
2197,358,849,1244,1809,2009,198,463,451,521,233,601,604,31
|
-0.6324042683431318,0.8056207329272186,0.2313650943574053,-0.01377469592003253,-0.33631253477906203,-0.4810044712723359,1.3273799247937976,0.6268724257185203,0.6473133664185765,0.5646389006836805,1.148018452189637,0.45777194879673416,0.45777194879673416,3.1093432588488037
| 2,702
|
Locomotory behavior
| 6
| 24
| 2.156996
| 0.031006
|
O15118,P54802,Q6Y7W6,P50897,O75844,Q8N2K0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
74,141,180,82,57,188
|
1706,74,57,1239,1714,1841,919,1118,317,619,2269,1445,82,2242,198,141,1169,601,180,188,877,2593,1665,2441
|
-0.2802102847132027,2.3553210205573603,2.5094973738711897,-0.01377469592003253,-0.2802102847132027,-0.36473682773465654,0.18391141717841533,0.06187795047934465,0.881460002398148,0.4359099189969065,-0.6949533822984102,-0.1176342396375531,2.2632150164335987,-0.6635325569459647,1.3273799247937976,1.678647365092368,0.036868377335003144,0.45777194879673416,1.4200644560622815,1.3895536705247618,0.2313650943574053,-1.353903802647287,-0.22508051495738804,-0.9234673291200788
| 2,702
|
Golgi to er retrograde transport
| 16
| 64
| 2.155989
| 0.031085
|
Q6NUQ1,Q13561,Q15363,Q9Y3B3,P24390,Q14203,O75935,O15260,P04350,Q9BVK6,Q9H0H5,Q9P2W9,Q9BVA1,P49755,P68371,Q9Y678
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
160,387,37,68,7,486,418,140,300,205,145,116,380,378,464,393
|
1539,1916,140,914,1586,1340,418,1394,993,300,920,7,1348,1442,2269,1852,2271,1161,1445,378,1002,1601,1602,1727,1974,1165,623,739,464,797,1206,1043,1084,2180,1933,2420,387,599,486,798,2064,1512,37,160,1615,2030,874,905,2363,908,670,380,205,2517,145,607,2602,116,1426,510,68,1104,393,1387
|
-0.17089694126863775,-0.4223492971351874,1.692221906453172,0.18391141717841533,-0.19787205833249796,-0.06526800225829026,0.687750303214672,-0.09134055376869563,0.13569066148578596,0.9369680850132093,0.18391141717841533,3.630300382746048,-0.06526800225829026,-0.1176342396375531,-0.6949533822984102,-0.36473682773465654,-0.6949533822984102,0.036868377335003144,-0.1176342396375531,0.7668911001385372,0.13569066148578596,-0.19787205833249796,-0.19787205833249796,-0.2802102847132027,-0.4515446964616516,0.036868377335003144,0.4359099189969065,0.3240467416918007,0.6268724257185203,0.27807073501123514,0.011651732815977752,0.1112864967658255,0.08668311743058034,-0.6015642502581877,-0.4223492971351874,-0.8898717216903321,0.74731846202068,0.45777194879673416,0.6062808758329494,0.27807073501123514,-0.5107324113409443,-0.14415202790824028,2.9694470635904917,1.581373621216261,-0.19787205833249796,-0.4810044712723359,0.2313650943574053,0.20773293514525631,-0.7910150544529415,0.20773293514525631,0.39168144268614885,0.7668911001385372,1.2957016226393265,-1.0964994453628252,1.6649938710643004,0.45777194879673416,-1.4309487853394973,1.8992357988485726,-0.09134055376869563,0.5855369618145146,2.424219700870432,0.08668311743058034,0.74731846202068,-0.06526800225829026
| 2,702
|
Action tremor
| 12
| 43
| 2.15482
| 0.031176
|
Q9UBB4,Q9NZJ7,P07602,P04350,P35637,O14773,Q99720,Q5JRX3,O15020,Q8N2K0,P31749,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
366,365,11,300,270,199,22,182,376,188,409,30
|
2315,199,559,376,1337,757,822,1712,1714,300,11,1675,1120,921,2497,998,1772,1250,409,1441,270,856,1724,969,1815,1929,710,30,553,182,2330,1015,188,2593,1946,22,842,1992,476,365,366,1667,820
|
-0.7586901436735312,1.3115908775571128,0.5010015722710037,0.7668911001385372,-0.06526800225829026,0.3011488166696212,0.254810254426627,-0.2802102847132027,-0.2802102847132027,0.9369680850132093,3.503168251453378,-0.25252550560044684,0.06187795047934465,0.18391141717841533,-1.0612014774574168,0.13569066148578596,-0.308138168176809,-0.01377469592003253,0.7077496739843829,-0.1176342396375531,1.026980616676179,0.2313650943574053,-0.2802102847132027,0.15989814001547026,-0.33631253477906203,-0.4223492971351874,0.3467667149096307,3.1093432588488037,0.5223730615720535,1.404856290131458,-0.7586901436735312,0.13569066148578596,1.3895536705247618,-1.353903802647287,-0.4223492971351874,3.3179623931981417,0.254810254426627,-0.4515446964616516,0.6268724257185203,0.8056207329272186,0.8056207329272186,-0.22508051495738804,0.27807073501123514
| 2,702
|
Active transmembrane transporter activity
| 30
| 72
| 2.150403
| 0.031523
|
O96000,O95169,Q9HD20,P04920,P12236,P13073,P05141,Q15388,O00400,P00403,P21281,Q9P0J0,O43676,Q9Y6M9,Q9Y6M7,Q9Y289,Q7KZN9,P08183,P51790,Q96ES6,Q9H2H9,O95202,P61421,Q9UDW1,Q9Y5K8,Q96QD8,Q9UBX3,Q16795,P16615,O15439
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
260,259,136,514,267,269,274,413,155,407,291,171,44,178,305,184,195,197,198,76,210,332,463,98,229,492,103,488,369,479
|
1107,155,1067,479,44,2521,757,2667,822,1151,2695,675,259,2296,332,2345,260,407,514,615,1674,274,1115,197,1435,893,1639,794,267,269,369,2376,531,1249,291,2127,680,617,1595,2468,2558,922,1721,856,2623,198,1683,1726,1498,463,1932,933,835,413,940,2250,488,195,691,76,492,779,210,136,171,103,98,1799,184,229,305,178
|
0.06187795047934465,1.5955163931080725,0.08668311743058034,0.6062808758329494,2.777797385123894,-1.1321541889327764,0.3011488166696212,-2.302553966333245,0.254810254426627,0.036868377335003144,-5.244856058642934,0.36931090448637094,1.0621410964140288,-0.7266710972825526,0.8438063884694104,-0.7910150544529415,1.0621410964140288,0.7077496739843829,0.5646389006836805,0.4359099189969065,-0.25252550560044684,1.0092219778652174,0.06187795047934465,1.3273799247937976,-0.1176342396375531,0.20773293514525631,-0.22508051495738804,0.27807073501123514,1.044619903415622,1.026980616676179,0.7863246738934979,-0.8236504561955251,0.5435848808587928,-0.01377469592003253,0.9733415184995973,-0.5710083209352036,0.36931090448637094,0.4359099189969065,-0.19787205833249796,-0.9916536280362304,-1.241316825230039,0.18391141717841533,-0.2802102847132027,0.2313650943574053,-1.54963172247134,1.3273799247937976,-0.25252550560044684,-0.2802102847132027,-0.14415202790824028,0.6268724257185203,-0.4223492971351874,0.18391141717841533,0.254810254426627,0.7077496739843829,0.18391141717841533,-0.6635325569459647,0.6062808758329494,1.3430697559709033,0.36931090448637094,2.3452866902285905,0.6062808758329494,0.3011488166696212,1.2797111548412214,1.7191369886638892,1.509380323825773,2.088833108363494,2.1337776504182426,-0.308138168176809,1.404856290131458,1.1815848149569044,0.9369680850132093,1.435179083173316
| 2,702
|
Multi multicellular organism process
| 8
| 26
| 2.144217
| 0.032015
|
Q9H9Y6,Q9BQE5,Q15363,Q96QD8,Q9H2H9,Q9UIQ6,P31749,P35613
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
288,34,37,492,210,58,409,159
|
1479,1390,1840,919,1882,2265,1848,2128,409,159,856,1199,520,1412,934,37,1686,1787,1576,492,34,2233,210,288,58,1879
|
-0.14415202790824028,-0.09134055376869563,-0.36473682773465654,0.18391141717841533,-0.3934145562501481,-0.6949533822984102,-0.36473682773465654,-0.5710083209352036,0.7077496739843829,1.581373621216261,0.2313650943574053,0.011651732815977752,0.5646389006836805,-0.09134055376869563,0.18391141717841533,2.9694470635904917,-0.25252550560044684,-0.308138168176809,-0.17089694126863775,0.6062808758329494,3.0547069293922724,-0.6324042683431318,1.2797111548412214,0.9913427102790784,2.500199007739095,-0.36473682773465654
| 2,702
|
Disproportionate short stature
| 8
| 21
| 2.143855
| 0.032045
|
Q03164,Q14739,O00116,P10644,Q15392,P16278,Q6DKJ4,Q9BV10
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
32,298,382,111,49,19,372,353
|
382,789,2396,593,111,19,2487,619,1445,32,298,2064,49,569,372,1518,1523,876,353,445,845
|
0.74731846202068,0.27807073501123514,-0.8566010715319217,0.45777194879673416,1.9360399599594456,3.3763606176597847,-1.0262546953488343,0.4359099189969065,-0.1176342396375531,3.095843374136502,0.9552170880450557,-0.5107324113409443,2.71205420662372,0.5010015722710037,0.7863246738934979,-0.14415202790824028,-0.14415202790824028,0.2313650943574053,0.8247808034059452,0.6676054254045067,0.254810254426627
| 2,702
|
Splenomegaly
| 23
| 77
| 2.140825
| 0.032288
|
P08236,Q13510,Q9NZ08,P07602,P54802,P16278,P31749,P21964,Q14108,Q6NUQ1,P21281,P15586,Q14739,Q15392,Q9H0U3,P10253,O15118,Q96A33,P28070,P00813,Q9NZJ7,P61916,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
261,134,137,11,141,19,409,408,30,160,291,164,298,49,443,317,74,330,207,225,365,240,125
|
512,2463,2448,2197,1762,74,1339,2547,992,2398,2319,225,1036,125,1114,2548,1843,1637,824,11,261,317,1882,1844,2265,1345,1677,2644,2004,164,19,1592,2322,291,408,1552,1848,207,617,2010,409,1349,1350,1888,449,2174,706,1200,1853,1683,1854,1256,141,2550,240,1129,1085,134,30,298,1414,49,2142,2638,505,160,1172,630,2678,1420,330,876,443,783,137,365,2441
|
0.5646389006836805,-0.9916536280362304,-0.957392920200188,-0.6324042683431318,-0.308138168176809,2.3553210205573603,-0.06526800225829026,-1.2045569767363151,0.13569066148578596,-0.8566010715319217,-0.7586901436735312,1.1815848149569044,0.1112864967658255,1.8365297753474792,0.06187795047934465,-1.2045569767363151,-0.36473682773465654,-0.22508051495738804,0.254810254426627,3.503168251453378,1.0621410964140288,0.881460002398148,-0.3934145562501481,-0.36473682773465654,-0.6949533822984102,-0.06526800225829026,-0.25252550560044684,-1.9299894948150549,-0.4810044712723359,1.5528345987170111,3.3763606176597847,-0.19787205833249796,-0.7586901436735312,0.9733415184995973,0.7077496739843829,-0.17089694126863775,-0.36473682773465654,1.2797111548412214,0.4359099189969065,-0.4810044712723359,0.7077496739843829,-0.06526800225829026,-0.06526800225829026,-0.3934145562501481,0.6473133664185765,-0.6015642502581877,0.3467667149096307,0.011651732815977752,-0.36473682773465654,-0.25252550560044684,-0.36473682773465654,-0.01377469592003253,1.678647365092368,-1.2045569767363151,1.1310694730368478,0.06187795047934465,0.08668311743058034,1.7191369886638892,3.1093432588488037,0.9552170880450557,-0.09134055376869563,2.71205420662372,-0.5710083209352036,-1.7139948007237693,0.5855369618145146,1.581373621216261,0.036868377335003144,0.4359099189969065,-2.5542477552427933,-0.09134055376869563,0.8626989686693847,0.2313650943574053,0.6676054254045067,0.3011488166696212,1.7191369886638892,0.8056207329272186,-0.9234673291200788
| 2,702
|
Negative regulation of mitochondrion organization
| 7
| 14
| 2.139928
| 0.032361
|
O75832,O60313,Q9H3K2,Q99536,P30536,P02786,P05141
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
190,239,303,339,114,333,274
|
239,190,1036,333,1843,274,2524,114,409,2102,1463,339,303,723
|
1.1310694730368478,1.3741556701287698,0.1112864967658255,0.8438063884694104,-0.36473682773465654,1.0092219778652174,-1.1321541889327764,1.9115709631930478,0.7077496739843829,-0.540732380985242,-0.1176342396375531,0.8438063884694104,0.9369680850132093,0.3467667149096307
| 2,702
|
FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]
| 6
| 10
| 2.138558
| 0.032471
|
Q02790,Q9NWM8,P26885,P62942,Q9Y680,Q96AY3
|
Sequence
|
InterPro Domain
|
interpro_domain
|
520,161,421,83,86,415
|
1333,421,83,565,520,1685,1736,415,161,86
|
-0.06526800225829026,0.687750303214672,2.2632150164335987,0.5010015722710037,0.5646389006836805,-0.25252550560044684,-0.2802102847132027,0.7077496739843829,1.581373621216261,2.199481174526684
| 2,702
|
Inorganic anion transmembrane transporter activity
| 6
| 20
| 2.135376
| 0.03273
|
P51790,Q9UBX3,Q9Y277,P21796,P45880,Q9C0H2
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
198,103,237,23,26,59
|
1836,479,1337,514,23,2558,26,198,1683,835,1364,583,2614,1179,779,59,103,237,1538,305
|
-0.36473682773465654,0.6062808758329494,-0.06526800225829026,0.5646389006836805,3.300030759770216,-1.241316825230039,3.2819030749164693,1.3273799247937976,-0.25252550560044684,0.254810254426627,-0.06526800225829026,0.47946851200506696,-1.5096459874254489,0.036868377335003144,0.3011488166696212,2.4814715373825837,2.088833108363494,1.148018452189637,-0.14415202790824028,0.9369680850132093
| 2,702
|
Protein insertion into membrane
| 9
| 28
| 2.128545
| 0.033292
|
Q9NS69,Q15070,P46379,Q96A33,Q9P0J0,Q8N4V1,O14737,Q9Y5J7,Q15629
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,167,168,330,171,79,242,254,29
|
242,1035,1337,499,758,1196,1440,1886,168,580,2651,167,29,869,426,2680,79,1138,665,330,1272,0,558,171,1065,343,254,650
|
1.1140084276296076,0.1112864967658255,-0.06526800225829026,0.5855369618145146,0.3011488166696212,0.011651732815977752,-0.1176342396375531,-0.3934145562501481,1.5239522688610696,0.47946851200506696,-2.0198857548091578,1.538436752547887,3.1293985059553213,0.2313650943574053,0.687750303214672,-3.0494230058693037,2.3250705886421623,0.06187795047934465,0.39168144268614885,0.8626989686693847,-0.01377469592003253,4.4345567444728164,0.5223730615720535,1.509380323825773,0.1112864967658255,0.8438063884694104,1.0795454359625347,0.4138804266239855
| 2,702
|
Epiphyseal stippling
| 7
| 11
| 2.124096
| 0.033662
|
P08236,P40855,O75381,Q14739,O00116,P10644,P38435
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
261,226,345,298,382,111,156
|
382,2396,345,261,111,156,226,762,298,799,445
|
0.74731846202068,-0.8566010715319217,0.8247808034059452,1.0621410964140288,1.9360399599594456,1.5955163931080725,1.1815848149569044,0.3011488166696212,0.9552170880450557,0.27807073501123514,0.6676054254045067
| 2,702
|
Protein transporter activity
| 8
| 13
| 2.117455
| 0.034221
|
Q9NS69,Q99595,Q9HD20,O14925,Q9UGP8,P61619,Q15388,P49755
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,1,136,206,575,580,413,378
|
206,758,891,378,580,2419,413,2150,1,136,0,575,650
|
1.2797111548412214,0.3011488166696212,0.20773293514525631,0.7668911001385372,0.47946851200506696,-0.8898717216903321,0.7077496739843829,-0.5710083209352036,4.159262994962356,1.7191369886638892,4.4345567444728164,0.5010015722710037,0.4138804266239855
| 2,702
|
Corneal opacity
| 14
| 45
| 2.11584
| 0.034358
|
P08236,P40855,O75381,Q13510,Q06136,O43505,P16278,O95202,P06280,P04062,Q6NUK1,P51648,P10619,O75844
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
261,226,345,134,106,78,19,332,215,125,414,219,63,57
|
2448,559,78,1803,2532,2522,2396,345,57,1807,332,1154,1036,125,1114,215,261,2605,63,19,1120,921,1597,226,2175,762,219,1002,1929,1258,2018,1977,2645,106,688,2021,134,976,1515,1050,414,608,445,1958,753
|
-0.957392920200188,0.5010015722710037,2.3250705886421623,-0.33631253477906203,-1.1681714201941449,-1.1321541889327764,-0.8566010715319217,0.8247808034059452,2.5094973738711897,-0.33631253477906203,0.8438063884694104,0.036868377335003144,0.1112864967658255,1.8365297753474792,0.06187795047934465,1.247422490494699,1.0621410964140288,-1.470087388879226,2.4530486238043636,3.3763606176597847,0.06187795047934465,0.18391141717841533,-0.19787205833249796,1.1815848149569044,-0.6015642502581877,0.3011488166696212,1.2311222135057562,0.13569066148578596,-0.4223492971351874,-0.01377469592003253,-0.4810044712723359,-0.4515446964616516,-1.9299894948150549,2.042939361579597,0.36931090448637094,-0.4810044712723359,1.7191369886638892,0.15989814001547026,-0.14415202790824028,0.1112864967658255,0.7077496739843829,0.45777194879673416,0.6676054254045067,-0.4223492971351874,0.3240467416918007
| 2,702
|
Organic anion transmembrane transporter activity
| 20
| 31
| 4.124256
| 0.000037
|
Q96QD8,Q8TB61,Q9H2H9,Q9Y6M7,O43808,Q9H2D1,P12236,O00400,Q9UBX3,Q96NB2,Q9BQT8,Q02978,P41440,Q99808,Q6NUK1,Q9HC21,P33527,P11166,O15439,P53985
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
389,136,138,143,147,22,415,170,47,176,50,183,321,338,344,220,348,222,248,254
|
170,248,147,889,435,605,1044,222,750,415,348,321,254,183,839,344,1191,136,176,389,338,50,22,138,630,220,47,666,681,933,143
|
1.6337233768883894,1.3186955452496854,1.7638347606018192,0.18916598311737365,0.7744188751377666,0.49160405626708076,0.05828124665914992,1.4031156606893533,0.31624613864460677,0.8224740869191085,0.9942651268493035,1.085181098032962,1.3044639973832475,1.540253330753097,0.24408206050486364,1.0095506891404633,-0.03766376468274858,1.8526312438376766,1.5939123156550052,0.8857323527866384,1.0399612405003023,2.578682101820039,3.1065707089213883,1.8400575311170198,0.47438206198749655,1.417026875112562,2.6626661752675664,0.42230424858015453,0.4048059034205665,0.17070624531058928,1.802114682609706
| 2,701
|
SLC superfamily of solute carriers
| 30
| 43
| 3.996392
| 0.000064
|
Q96QD8,Q8TB61,Q9H2H9,Q70HW3,Q9Y6M7,Q9NZJ7,O43808,Q9H2D1,O95202,P12236,O00400,Q9UBX3,Q96NB2,Q6NT16,Q9BQT8,O95563,Q02978,P41440,Q99808,Q8IXU6,Q6NUK1,Q9HC21,Q9Y6C9,P11166,Q8NEW0,Q9BXP2,O43772,Q9H0U3,Q9H2V7,P53985
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
389,136,138,11,143,146,147,22,405,415,170,47,176,49,50,435,183,321,338,87,344,220,92,222,95,359,103,238,246,254
|
170,103,147,889,405,435,462,605,1044,222,750,415,321,254,551,183,839,1961,49,344,1191,11,87,95,136,176,389,338,50,359,238,22,138,246,630,220,146,47,666,681,933,92,143
|
1.6337233768883894,2.060949321084514,1.7638347606018192,0.18916598311737365,0.8383751777967641,0.7744188751377666,0.7258267538427401,0.49160405626708076,0.05828124665914992,1.4031156606893533,0.31624613864460677,0.8224740869191085,1.085181098032962,1.3044639973832475,0.5767080236830171,1.540253330753097,0.24408206050486364,-0.5082402040270202,2.5892707322696364,1.0095506891404633,-0.03766376468274858,3.617915206963102,2.1789349159101077,2.1203470954716264,1.8526312438376766,1.5939123156550052,0.8857323527866384,1.0399612405003023,2.578682101820039,0.9635315701724516,1.3470190066264098,3.1065707089213883,1.8400575311170198,1.332880448717388,0.47438206198749655,1.417026875112562,1.7766325496335293,2.6626661752675664,0.42230424858015453,0.4048059034205665,0.17070624531058928,2.1555955949755234,1.802114682609706
| 2,701
|
Intrinsic component of mitochondrial inner membrane
| 26
| 30
| 3.705808
| 0.000211
|
Q99595,Q16891,Q5XKP0,Q9Y2R0,Q13505,Q00325,Q96NB2,O75431,O95563,Q9BUR5,Q15070,P17152,Q6UXV4,O14925,Q53H12,Q9Y512,Q8NE86,Q96ER9,Q9Y4W6,Q9NVH1,Q9HC21,Q9H3K2,Q16134,O75880,Q9UG56,Q6P4A7
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
3,388,273,24,296,551,176,309,435,186,56,320,200,196,596,212,598,468,469,475,220,223,608,604,361,120
|
196,309,604,435,320,2594,551,296,56,608,388,596,273,120,200,598,468,176,3,186,223,630,1661,220,475,1335,361,24,469,212
|
1.4859193366122214,1.115067853889435,0.49160405626708076,0.7744188751377666,1.085181098032962,-1.3373751235719122,0.5767080236830171,1.1595152238833708,2.5360636019540204,0.49160405626708076,0.8857323527866384,0.5087582951969946,1.2470652835370355,1.951920624080694,1.4859193366122214,0.5087582951969946,0.7258267538427401,1.5939123156550052,4.492615277702867,1.540253330753097,1.4031156606893533,0.47438206198749655,-0.3180510829696362,1.417026875112562,0.7095080229146791,-0.11596206747168612,0.9635315701724516,2.973351412079002,0.7258267538427401,1.4447157506111374
| 2,701
|
Membrane lipid metabolic process
| 13
| 30
| 3.679804
| 0.000233
|
P07602,P17900,Q9NZ01,Q99805,Q8NBX0,P50897,O95470,P04062,Q06136,Q9NZJ7,Q9P035,Q13510,Q96G23
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
31,163,6,202,59,74,144,177,18,146,208,119,27
|
1972,2071,144,177,1022,1075,1281,31,829,809,163,797,2429,74,18,119,1509,596,59,2472,287,27,1300,420,202,504,6,146,208,1168
|
-0.5298892096352652,-0.5954826549590951,1.7893924505266094,1.5805599528095038,0.07722049678650203,0.03925969392486323,-0.09625596283480581,2.8458055936098234,0.24408206050486364,0.2622351395530162,1.6862398498357258,0.28031310881637544,-0.9628253083803223,2.3163672654572762,3.244826799017829,1.951920624080694,-0.23609532189713084,0.5087582951969946,2.48218674176581,-1.035240699093695,1.1888955874119858,2.92474561480173,-0.09625596283480581,0.8224740869191085,1.4859193366122214,0.6601814574178648,3.953135916812116,1.7766325496335293,1.4722284064322555,-0.01830586786658518
| 2,701
|
Active ion transmembrane transporter activity
| 25
| 43
| 3.574297
| 0.000351
|
P00403,Q96ES6,Q96QD8,Q9H2H9,Q9Y6M7,P51790,Q7KZN9,O95202,P12236,P10606,O00400,P98194,Q02978,Q9Y5K8,Q9HD20,P41440,P04920,P31930,P13073,P33527,Q9BXP2,P05023,Q9UDW1,O15439,P16615
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
251,128,389,138,143,280,152,405,415,298,170,178,183,452,58,321,462,81,343,348,359,243,118,248,252
|
170,248,405,251,462,243,1118,605,1568,1044,749,298,750,415,343,252,1024,1076,1343,1602,699,81,348,1882,2191,321,280,813,471,178,551,183,152,128,389,359,138,58,118,1433,681,452,143
|
1.6337233768883894,1.3186955452496854,0.8383751777967641,1.3044639973832475,0.7258267538427401,1.332880448717388,0.000966854535827841,0.49160405626708076,-0.27688196692354466,0.05828124665914992,0.31624613864460677,1.1447500131709183,0.31624613864460677,0.8224740869191085,1.0095506891404633,1.3044639973832475,0.07722049678650203,0.03925969392486323,-0.1357571511500396,-0.2974182770678407,0.36959730040846983,2.248201202031891,0.9942651268493035,-0.4652592172226013,-0.6844888552895658,1.085181098032962,1.203511402271728,0.2622351395530162,0.7095080229146791,1.5805599528095038,0.5767080236830171,1.540253330753097,1.7381246312443195,1.9025621688075542,0.8857323527866384,0.9635315701724516,1.8400575311170198,2.5038189105500694,1.9763891703113325,-0.1756174312141384,0.4048059034205665,0.7582817372111945,1.802114682609706
| 2,701
|
Intrinsic component of mitochondrial membrane
| 32
| 44
| 3.562688
| 0.000367
|
Q99595,Q16891,Q5XKP0,Q9Y2R0,Q8IWA4,Q16611,Q13505,Q00325,Q96NB2,O75431,O95563,Q9BUR5,Q15070,P57105,P17152,Q6UXV4,O96008,O14925,Q53H12,Q9Y512,Q8NE86,Q96ER9,Q9Y4W6,Q9NVH1,Q9HC21,Q9H3K2,Q16134,O75880,Q9UG56,Q8TB36,Q15388,Q6P4A7
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
3,388,273,24,545,37,296,551,176,309,435,186,56,315,320,200,326,196,596,212,598,468,469,475,220,223,608,604,361,244,498,120
|
196,309,604,684,435,326,750,320,2594,315,551,296,56,498,608,37,388,596,273,120,200,545,1017,1396,598,244,468,176,3,906,928,186,1059,223,630,1661,220,475,1335,361,1065,24,469,212
|
1.4859193366122214,1.115067853889435,0.49160405626708076,0.38723710682081225,0.7744188751377666,1.0701601286370668,0.31624613864460677,1.085181098032962,-1.3373751235719122,1.1001502232099265,0.5767080236830171,1.1595152238833708,2.5360636019540204,0.6601814574178648,0.49160405626708076,2.775514718206515,0.8857323527866384,0.5087582951969946,1.2470652835370355,1.951920624080694,1.4859193366122214,0.593531179510868,0.0960781397108018,-0.1556420051329787,0.5087582951969946,1.332880448717388,0.7258267538427401,1.5939123156550052,4.492615277702867,0.18916598311737365,0.17070624531058928,1.540253330753097,0.05828124665914992,1.4031156606893533,0.47438206198749655,-0.3180510829696362,1.417026875112562,0.7095080229146791,-0.11596206747168612,0.9635315701724516,0.05828124665914992,2.973351412079002,0.7258267538427401,1.4447157506111374
| 2,701
|
Organic anion transport
| 25
| 43
| 3.491251
| 0.000481
|
Q96QD8,Q8TB61,Q9H2H9,Q9Y6M7,Q9NZJ7,O43808,Q9H2D1,P07602,P12236,O00400,Q9UBX3,Q96NB2,Q9BQT8,O95563,Q02978,P41440,P04920,Q99808,Q6NUK1,Q9HC21,P33527,P11166,Q08722,O15439,P53985
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
389,136,138,143,146,147,22,31,415,170,47,176,50,435,183,321,462,338,344,220,348,222,354,248,254
|
170,248,147,889,537,435,890,462,605,1043,31,1044,222,750,415,716,621,470,348,321,2574,254,183,354,839,344,1191,136,1836,176,389,338,50,22,138,630,220,146,47,666,681,933,143
|
1.6337233768883894,1.3186955452496854,1.7638347606018192,0.18916598311737365,0.593531179510868,0.7744188751377666,0.18916598311737365,0.7258267538427401,0.49160405626708076,0.05828124665914992,2.8458055936098234,0.05828124665914992,1.4031156606893533,0.31624613864460677,0.8224740869191085,0.351885919191322,0.47438206198749655,0.7095080229146791,0.9942651268493035,1.085181098032962,-1.234355168597917,1.3044639973832475,1.540253330753097,0.9789255457318856,0.24408206050486364,1.0095506891404633,-0.03766376468274858,1.8526312438376766,-0.4226942464977029,1.5939123156550052,0.8857323527866384,1.0399612405003023,2.578682101820039,3.1065707089213883,1.8400575311170198,0.47438206198749655,1.417026875112562,1.7766325496335293,2.6626661752675664,0.42230424858015453,0.4048059034205665,0.17070624531058928,1.802114682609706
| 2,701
|
Anion transmembrane transporter activity
| 27
| 46
| 3.470834
| 0.000519
|
Q96QD8,Q8TB61,Q9H2H9,Q9Y6M7,O43808,Q9H2D1,P51790,P45880,P12236,Q9Y277,O00400,Q9UBX3,Q96NB2,Q9BQT8,O95563,Q02978,P21796,P41440,Q99808,Q6NUK1,Q9HC21,P33527,P11166,Q9C0H2,Q9BXP2,O15439,P53985
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
389,136,138,143,147,22,280,28,415,166,170,47,176,50,435,183,62,321,338,344,220,348,222,94,359,248,254
|
2227,170,248,536,147,889,435,462,605,1044,222,750,415,62,348,321,28,280,813,254,183,839,518,1961,344,1191,136,1836,176,389,566,338,50,359,94,22,138,630,220,47,666,166,681,933,2099,143
|
-0.7296754780456444,1.6337233768883894,1.3186955452496854,0.593531179510868,1.7638347606018192,0.18916598311737365,0.7744188751377666,0.7258267538427401,0.49160405626708076,0.05828124665914992,1.4031156606893533,0.31624613864460677,0.8224740869191085,2.460444745964291,0.9942651268493035,1.085181098032962,2.905147117866422,1.203511402271728,0.2622351395530162,1.3044639973832475,1.540253330753097,0.24408206050486364,0.6269838228448695,-0.5082402040270202,1.0095506891404633,-0.03766376468274858,1.8526312438376766,-0.4226942464977029,1.5939123156550052,0.8857323527866384,0.559819657694308,1.0399612405003023,2.578682101820039,0.9635315701724516,2.1321287594832308,3.1065707089213883,1.8400575311170198,0.47438206198749655,1.417026875112562,2.6626661752675664,0.42230424858015453,1.6862398498357258,0.4048059034205665,0.17070624531058928,-0.5954826549590951,1.802114682609706
| 2,701
|
Anion transmembrane transport
| 25
| 41
| 3.440658
| 0.00058
|
Q4KMQ2,Q8TB61,Q9Y6M7,O43808,Q9UHG3,Q9H2D1,P51790,P45880,O75915,P12236,Q9Y277,Q9UBX3,Q96NB2,Q9BQT8,P08183,O95563,Q02978,P21796,P41440,P04920,Q9HC21,P33527,Q9BXP2,O15439,P53985
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
518,136,143,147,20,22,280,28,537,415,166,47,176,50,180,435,183,62,321,462,220,348,359,248,254
|
248,147,889,537,435,462,605,1043,180,1044,750,415,62,348,321,28,2574,280,813,254,551,183,839,518,136,1836,176,50,359,22,630,220,1802,47,20,666,166,681,1373,933,143
|
1.3186955452496854,1.7638347606018192,0.18916598311737365,0.593531179510868,0.7744188751377666,0.7258267538427401,0.49160405626708076,0.05828124665914992,1.5537307142177417,0.05828124665914992,0.31624613864460677,0.8224740869191085,2.460444745964291,0.9942651268493035,1.085181098032962,2.905147117866422,-1.234355168597917,1.203511402271728,0.2622351395530162,1.3044639973832475,0.5767080236830171,1.540253330753097,0.24408206050486364,0.6269838228448695,1.8526312438376766,-0.4226942464977029,1.5939123156550052,2.578682101820039,0.9635315701724516,3.1065707089213883,0.47438206198749655,1.417026875112562,-0.40156531384122846,2.6626661752675664,3.1438803833162297,0.42230424858015453,1.6862398498357258,0.4048059034205665,-0.1357571511500396,0.17070624531058928,1.802114682609706
| 2,701
|
Intrinsic component of endoplasmic reticulum membrane
| 21
| 45
| 3.35706
| 0.000788
|
Q9NZ01,Q8TB61,O95470,Q92643,Q6NTF9,Q9UBM7,P61619,Q15629,O75844,Q9Y282,Q9UM00,Q86XL3,Q8N4V1,Q9P035,P57088,Q9NQC3,Q9BUN8,Q96A33,Q8TCT9,Q8TCT8,P51572
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
6,136,144,287,156,36,169,41,43,54,318,187,70,208,227,122,110,236,112,250,253
|
1277,335,1767,43,620,144,2105,563,2356,570,2262,253,227,169,543,1751,2145,41,465,156,842,187,70,660,136,250,112,287,236,1300,927,110,534,692,122,6,208,1197,1729,36,560,318,54,579,710
|
-0.09625596283480581,1.0399612405003023,-0.40156531384122846,2.734822878575379,0.47438206198749655,1.7893924505266094,-0.6175661397525806,0.559819657694308,-0.8680821176442824,0.5428655840352268,-0.7524437006538256,1.3044639973832475,1.3891595529580087,1.6469125414193932,0.593531179510868,-0.3805374686703146,-0.6397609283995005,2.745032234471493,0.7258267538427401,1.7122602692585014,0.24408206050486364,1.526733762162025,2.3723562686361177,0.42230424858015453,1.8526312438376766,1.3186955452496854,2.0369584700842114,1.1888955874119858,1.3470190066264098,-0.09625596283480581,0.17070624531058928,2.0489706294219476,0.6102896170952945,0.38723710682081225,1.93963397583531,3.953135916812116,1.4722284064322555,-0.03766376468274858,-0.3596097669606752,2.8057811853844417,0.5767080236830171,1.1001502232099265,2.5574259051028014,0.5428655840352268,0.36959730040846983
| 2,701
|
Organophosphate ester transport
| 15
| 26
| 3.290528
| 0.001
|
O15439,P41440,Q8WTV0,Q08722,Q8TB61,P61916,O00400,Q99808,O43808,Q14108,Q9H2D1,P08183,Q6NUK1,Q9HC21,P33527
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
248,321,322,354,136,72,170,338,147,21,22,180,344,220,348
|
170,248,147,605,180,750,415,797,1440,348,321,1050,72,354,21,518,344,1296,136,1836,322,338,1194,22,220,1168
|
1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,1.5537307142177417,0.31624613864460677,0.8224740869191085,0.28031310881637544,-0.19568424190462033,0.9942651268493035,1.085181098032962,0.05828124665914992,2.36121680514361,0.9789255457318856,3.1159288248830843,0.6269838228448695,1.0095506891404633,-0.09625596283480581,1.8526312438376766,-0.4226942464977029,1.085181098032962,1.0399612405003023,-0.03766376468274858,3.1065707089213883,1.417026875112562,-0.01830586786658518
| 2,701
|
Receptor
| 11
| 33
| 3.267283
| 0.001086
|
O15173,Q9NS69,O15118,Q8WTV0,P24390,P11279,Q99623,Q14739,Q14108,O00264,Q9Y5M8
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
127,2,130,322,9,80,245,53,21,308,158
|
308,1811,1693,130,127,808,1043,562,2281,1382,1772,1149,80,1601,1245,1314,9,381,677,1647,21,53,839,597,322,1426,245,501,2,560,1732,158,1971
|
1.115067853889435,-0.4226942464977029,-0.3596097669606752,1.8901336133115505,1.9025621688075542,0.2622351395530162,0.05828124665914992,0.559819657694308,-0.7753301127313307,-0.1556420051329787,-0.40156531384122846,-0.01830586786658518,2.248201202031891,-0.2974182770678407,-0.07663805632366444,-0.11596206747168612,3.6674600654956833,0.9014040733816177,0.4048059034205665,-0.3180510829696362,3.1159288248830843,2.5574259051028014,0.24408206050486364,0.5087582951969946,1.085181098032962,-0.1756174312141384,1.332880448717388,0.6601814574178648,5.159139452386764,0.5767080236830171,-0.3596097669606752,1.7122602692585014,-0.5082402040270202
| 2,701
|
Lysosomal lumen
| 16
| 32
| 3.258773
| 0.001119
|
P07602,P17900,P61916,P10619,P50897,Q8IV08,P10253,P54802,P04062,Q9NZJ7,P38435,Q14108,P08236,Q8NHP8,Q13510,O14773
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
31,163,72,168,74,105,508,464,177,146,114,21,342,410,119,319
|
1766,1307,319,536,177,1022,1075,1281,31,829,1176,342,508,168,673,1979,1851,809,163,114,2509,74,464,72,119,21,105,2005,410,2126,724,146
|
-0.40156531384122846,-0.11596206747168612,1.085181098032962,0.593531179510868,1.5805599528095038,0.07722049678650203,0.03925969392486323,-0.09625596283480581,2.8458055936098234,0.24408206050486364,-0.03766376468274858,1.0095506891404633,0.6436142777409396,1.6469125414193932,0.4048059034205665,-0.5298892096352652,-0.4439252239854569,0.2622351395530162,1.6862398498357258,2.0128330114691035,-1.1088623151263601,2.3163672654572762,0.7258267538427401,2.36121680514361,1.951920624080694,3.1159288248830843,2.060949321084514,-0.5298892096352652,0.8383751777967641,-0.6175661397525806,0.351885919191322,1.7766325496335293
| 2,701
|
Carboxylic acid transport
| 19
| 30
| 3.212055
| 0.001318
|
Q96QD8,Q9H2H9,Q9UJS0,Q9NZJ7,Q9H2D1,P07602,O75915,Q9UBX3,Q96NB2,Q9BQT8,O95563,Q02978,P41440,P33527,P28288,Q9H9B4,P21359,O15439,P53985
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
389,138,666,146,22,31,537,47,176,50,435,183,321,348,470,630,621,248,254
|
248,889,537,435,890,1043,31,1044,716,621,470,348,321,2574,254,183,839,1191,1836,176,389,50,22,138,630,146,47,666,681,933
|
1.3186955452496854,0.18916598311737365,0.593531179510868,0.7744188751377666,0.18916598311737365,0.05828124665914992,2.8458055936098234,0.05828124665914992,0.351885919191322,0.47438206198749655,0.7095080229146791,0.9942651268493035,1.085181098032962,-1.234355168597917,1.3044639973832475,1.540253330753097,0.24408206050486364,-0.03766376468274858,-0.4226942464977029,1.5939123156550052,0.8857323527866384,2.578682101820039,3.1065707089213883,1.8400575311170198,0.47438206198749655,1.7766325496335293,2.6626661752675664,0.42230424858015453,0.4048059034205665,0.17070624531058928
| 2,701
|
Organic acid transmembrane transport
| 20
| 29
| 3.178475
| 0.001481
|
Q96QD8,Q9H2H9,Q9UJS0,Q9H2D1,O75915,Q9UBX3,Q96NB2,Q9BQT8,P08183,O95563,Q02978,P23786,P41440,P33527,P28288,P11166,O43772,Q9H9B4,P53985,P31749
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
389,138,666,22,537,47,176,50,180,435,183,182,321,348,470,222,103,630,254,636
|
103,889,537,435,1043,180,1044,222,182,470,636,1248,348,321,2574,254,183,839,1836,176,389,50,22,138,630,47,666,681,933
|
2.060949321084514,0.18916598311737365,0.593531179510868,0.7744188751377666,0.05828124665914992,1.5537307142177417,0.05828124665914992,1.4031156606893533,1.540253330753097,0.7095080229146791,0.4570917855835725,-0.07663805632366444,0.9942651268493035,1.085181098032962,-1.234355168597917,1.3044639973832475,1.540253330753097,0.24408206050486364,-0.4226942464977029,1.5939123156550052,0.8857323527866384,2.578682101820039,3.1065707089213883,1.8400575311170198,0.47438206198749655,2.6626661752675664,0.42230424858015453,0.4048059034205665,0.17070624531058928
| 2,701
|
Sphingolipid metabolic process
| 11
| 25
| 3.175958
| 0.001493
|
P07602,P17900,Q9NZ01,Q99805,P50897,O95470,P04062,Q06136,Q9NZJ7,Q13510,Q96G23
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
31,163,6,202,74,144,177,18,146,119,27
|
1972,2071,144,177,1075,1281,31,829,809,163,797,2429,74,18,119,1509,596,2472,27,202,504,6,146,208,1168
|
-0.5298892096352652,-0.5954826549590951,1.7893924505266094,1.5805599528095038,0.03925969392486323,-0.09625596283480581,2.8458055936098234,0.24408206050486364,0.2622351395530162,1.6862398498357258,0.28031310881637544,-0.9628253083803223,2.3163672654572762,3.244826799017829,1.951920624080694,-0.23609532189713084,0.5087582951969946,-1.035240699093695,2.92474561480173,1.4859193366122214,0.6601814574178648,3.953135916812116,1.7766325496335293,1.4722284064322555,-0.01830586786658518
| 2,701
|
Mitochondrial respiratory chain complex assembly
| 14
| 32
| 3.166207
| 0.001544
|
O96000,O43676,Q9P0J0,Q9BVV7,O95169,O95168,O95831,Q6DKK2,Q86Y39,Q69YU5,Q9Y512,Q9Y2R0,Q15070,Q9Y6M9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
290,4,133,390,295,325,297,102,104,46,212,24,56,30
|
2556,4,1973,2516,478,1528,604,2230,325,295,2017,297,290,2046,1256,1828,56,399,609,46,102,757,104,1138,390,726,1235,133,617,24,212,30
|
-1.2089703136081216,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,0.49160405626708076,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.5516452556198194,1.1447500131709183,1.1742303044100273,-0.5735093847387928,-0.07663805632366444,-0.4226942464977029,2.5360636019540204,0.8542183112675076,0.49160405626708076,2.693739761093138,2.072894727430521,0.31624613864460677,2.060949321084514,0.000966854535827841,0.8857323527866384,0.351885919191322,-0.05710757719101301,1.8901336133115505,0.49160405626708076,2.973351412079002,1.4447157506111374,2.8557533308424374
| 2,701
|
Sphingolipid metabolism
| 9
| 24
| 3.108156
| 0.001883
|
P07602,P17900,P10619,O95470,P04062,Q06136,Q9NZJ7,Q13510,Q96G23
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
31,163,168,144,177,18,146,119,27
|
1277,1972,2071,536,1117,144,177,1075,1281,31,829,168,809,163,797,218,18,119,1509,27,927,504,146,1168
|
-0.09625596283480581,-0.5298892096352652,-0.5954826549590951,0.593531179510868,0.000966854535827841,1.7893924505266094,1.5805599528095038,0.03925969392486323,-0.09625596283480581,2.8458055936098234,0.24408206050486364,1.6469125414193932,0.2622351395530162,1.6862398498357258,0.28031310881637544,1.417026875112562,3.244826799017829,1.951920624080694,-0.23609532189713084,2.92474561480173,0.17070624531058928,0.6601814574178648,1.7766325496335293,-0.01830586786658518
| 2,701
|
Anion transport
| 45
| 66
| 3.074521
| 0.002108
|
Q96QD8,Q4KMQ2,Q9H2H9,Q8TB61,Q15907,Q9Y6M7,Q9NZJ7,Q9UHG3,O43808,Q9H2D1,P51790,P45880,P07602,O75915,O43681,P12236,Q9Y277,O00400,Q00325,Q96NB2,Q9UBX3,Q96S66,Q9BQT8,P08183,O95563,Q02978,Q9H0H5,P21796,P41440,P30536,P04920,Q99808,Q6NUK1,Q9HC21,P33527,P28288,Q9C0H2,P11166,Q08722,P05141,Q9BXP2,Q9H9B4,P54105,O15439,P53985
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
389,518,138,136,266,143,146,20,147,22,280,28,31,537,536,415,166,170,551,176,47,566,50,180,435,183,450,62,321,195,462,338,344,220,348,470,94,222,354,605,359,630,623,248,254
|
2227,170,248,536,147,1628,889,537,435,890,462,605,1043,31,180,1044,222,750,415,716,621,62,470,195,348,321,28,2574,280,813,254,623,551,183,354,839,266,518,1961,344,1191,136,1836,176,389,566,338,50,359,94,450,22,138,630,220,1802,146,47,20,666,166,681,1373,933,2099,143
|
-0.7296754780456444,1.6337233768883894,1.3186955452496854,0.593531179510868,1.7638347606018192,-0.3180510829696362,0.18916598311737365,0.593531179510868,0.7744188751377666,0.18916598311737365,0.7258267538427401,0.49160405626708076,0.05828124665914992,2.8458055936098234,1.5537307142177417,0.05828124665914992,1.4031156606893533,0.31624613864460677,0.8224740869191085,0.351885919191322,0.47438206198749655,2.460444745964291,0.7095080229146791,1.4995670283946096,0.9942651268493035,1.085181098032962,2.905147117866422,-1.234355168597917,1.203511402271728,0.2622351395530162,1.3044639973832475,0.47438206198749655,0.5767080236830171,1.540253330753097,0.9789255457318856,0.24408206050486364,1.2614864555637981,0.6269838228448695,-0.5082402040270202,1.0095506891404633,-0.03766376468274858,1.8526312438376766,-0.4226942464977029,1.5939123156550052,0.8857323527866384,0.559819657694308,1.0399612405003023,2.578682101820039,0.9635315701724516,2.1321287594832308,0.7582817372111945,3.1065707089213883,1.8400575311170198,0.47438206198749655,1.417026875112562,-0.40156531384122846,1.7766325496335293,2.6626661752675664,3.1438803833162297,0.42230424858015453,1.6862398498357258,0.4048059034205665,-0.1357571511500396,0.17070624531058928,-0.5954826549590951,1.802114682609706
| 2,701
|
Receptor
| 11
| 25
| 3.045507
| 0.002323
|
Q8WTV0,Q9BUN8,Q9UQB8,Q9NR77,O75381,Q14108,Q567V2,A6NIH7,Q13432,P57105,Q6NTF9
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
322,110,75,113,339,21,86,55,255,315,156
|
55,1626,1376,339,713,1737,1043,1601,1314,315,2144,255,355,21,86,156,322,1399,110,708,113,1113,1561,75,862
|
2.5467580817021362,-0.3180510829696362,-0.1556420051329787,1.0247826043693027,0.351885919191322,-0.3805374686703146,0.05828124665914992,-0.2974182770678407,-0.11596206747168612,1.1001502232099265,-0.6397609283995005,1.3044639973832475,0.9789255457318856,3.1159288248830843,2.2021480739281882,1.7122602692585014,1.085181098032962,-0.1556420051329787,2.0489706294219476,0.36959730040846983,2.024912659220012,0.02015513431309902,-0.25644127155135765,2.2937653755220717,0.22585325728994807
| 2,701
|
Organic acid transport
| 19
| 41
| 3.045461
| 0.002323
|
Q96QD8,Q9H2H9,O43808,Q9H2D1,Q9UBX3,Q96NB2,Q9BQT8,Q01469,P08183,O95563,Q02978,P23786,P41440,P33527,P11166,O43772,Q6P4A7,O15439,P53985
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
389,138,147,22,47,176,50,51,180,435,183,182,321,348,222,103,120,248,254
|
248,103,147,889,537,435,1437,2583,890,1043,1633,180,1044,222,716,621,182,470,1820,636,1248,348,321,2574,254,51,183,839,1191,120,1836,176,389,50,22,138,630,47,666,681,933
|
1.3186955452496854,2.060949321084514,1.7638347606018192,0.18916598311737365,0.593531179510868,0.7744188751377666,-0.19568424190462033,-1.3113946688909883,0.18916598311737365,0.05828124665914992,-0.3180510829696362,1.5537307142177417,0.05828124665914992,1.4031156606893533,0.351885919191322,0.47438206198749655,1.540253330753097,0.7095080229146791,-0.4226942464977029,0.4570917855835725,-0.07663805632366444,0.9942651268493035,1.085181098032962,-1.234355168597917,1.3044639973832475,2.568067202131094,1.540253330753097,0.24408206050486364,-0.03766376468274858,1.951920624080694,-0.4226942464977029,1.5939123156550052,0.8857323527866384,2.578682101820039,3.1065707089213883,1.8400575311170198,0.47438206198749655,2.6626661752675664,0.42230424858015453,0.4048059034205665,0.17070624531058928
| 2,701
|
Mitochondrial membrane organization
| 26
| 43
| 3.028634
| 0.002457
|
Q9NS69,Q16891,Q9P0J0,P50542,Q8WWC4,Q5XKP0,Q9Y5J7,O95202,P45880,Q8IWA4,Q16611,Q3ZCQ8,Q13505,O75431,Q9BUR5,Q15070,P17152,O60313,Q6UXV4,Q53H12,Q9Y5J9,Q9Y512,Q9Y4W6,Q9NVH1,Q9Y276,Q9H3K2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,388,133,516,140,273,276,405,28,545,37,417,296,309,186,56,320,189,200,596,209,212,469,475,617,223
|
696,826,189,309,684,405,1096,605,1176,715,750,320,2571,1497,2110,2594,2385,28,516,870,296,56,37,388,417,596,273,200,545,1017,1396,140,186,223,2,475,1335,133,617,469,212,276,209
|
0.36959730040846983,0.24408206050486364,1.5131717487404053,1.115067853889435,0.38723710682081225,0.8383751777967641,0.02015513431309902,0.49160405626708076,-0.03766376468274858,0.351885919191322,0.31624613864460677,1.085181098032962,-1.234355168597917,-0.23609532189713084,-0.6175661397525806,-1.3373751235719122,-0.8915779896099613,2.905147117866422,0.6269838228448695,0.20754810800791113,1.1595152238833708,2.5360636019540204,2.775514718206515,0.8857323527866384,0.8224740869191085,0.5087582951969946,1.2470652835370355,1.4859193366122214,0.593531179510868,0.0960781397108018,-0.1556420051329787,1.8147994633249862,1.540253330753097,1.4031156606893533,5.159139452386764,0.7095080229146791,-0.11596206747168612,1.8901336133115505,0.49160405626708076,0.7258267538427401,1.4447157506111374,1.2325959289574466,1.4722284064322555
| 2,701
|
Inorganic anion transport
| 19
| 27
| 3.024061
| 0.002494
|
Q4KMQ2,Q9Y6M7,Q9UHG3,P51790,P45880,O43681,Q9Y277,Q00325,Q9UBX3,P08183,Q02978,Q9H0H5,P21796,P30536,P04920,P33527,Q9C0H2,Q9BXP2,O15439
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
518,143,20,280,28,536,166,551,47,180,183,450,62,195,462,348,94,359,248
|
2227,248,536,462,180,62,195,348,28,280,813,623,551,183,518,1961,1836,566,359,94,450,47,20,166,681,2099,143
|
-0.7296754780456444,1.3186955452496854,0.593531179510868,0.7258267538427401,1.5537307142177417,2.460444745964291,1.4995670283946096,0.9942651268493035,2.905147117866422,1.203511402271728,0.2622351395530162,0.47438206198749655,0.5767080236830171,1.540253330753097,0.6269838228448695,-0.5082402040270202,-0.4226942464977029,0.559819657694308,0.9635315701724516,2.1321287594832308,0.7582817372111945,2.6626661752675664,3.1438803833162297,1.6862398498357258,0.4048059034205665,-0.5954826549590951,1.802114682609706
| 2,701
|
Glycerophospholipid biosynthetic process
| 18
| 30
| 3.015458
| 0.002566
|
Q10713,O15228,Q9BTU6,Q6P1A2,Q9NX62,O14735,Q6IAN0,Q9UG56,O95674,Q9NTJ5,Q6UWP7,P48651,Q9NPH0,P35790,Q01469,Q8NF37,Q92643,Q96BW9
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
161,289,324,586,559,642,585,361,172,694,626,175,207,365,51,184,287,679
|
1523,642,289,1437,172,365,983,175,51,1219,2144,161,585,586,626,184,902,287,679,1486,1300,926,1585,324,1842,207,693,694,559,361
|
-0.25644127155135765,0.439732694154855,1.1742303044100273,-0.19568424190462033,1.6072235088664195,0.9480828206502808,0.11485486211702632,1.5939123156550052,2.568067202131094,-0.05710757719101301,-0.6397609283995005,1.6992696820323683,0.5258452995193653,0.5258452995193653,0.47438206198749655,1.540253330753097,0.18916598311737365,1.1888955874119858,0.4048059034205665,-0.21584326062426626,-0.09625596283480581,0.17070624531058928,-0.27688196692354466,1.085181098032962,-0.4226942464977029,1.4722284064322555,0.38723710682081225,0.38723710682081225,0.5767080236830171,0.9635315701724516
| 2,701
|
Protein targeting to mitochondrion
| 18
| 39
| 2.967406
| 0.003003
|
Q10713,Q9NS69,Q99595,P30536,Q9P0J0,Q9BVV7,Q3ZCQ8,O96008,O95831,P51572,O14925,Q8TB36,P55786,Q9Y5J7,Q9Y5J9,Q9Y512,Q99797,Q8N4H5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
161,2,3,195,133,390,417,326,297,253,196,244,17,276,209,212,317,32
|
1306,826,196,712,1493,684,1771,297,326,1176,2654,2636,195,2110,583,253,17,2319,161,498,417,596,425,992,32,244,1839,3,317,390,1059,2178,2,133,2069,1522,212,276,209
|
-0.11596206747168612,0.24408206050486364,1.4859193366122214,0.351885919191322,-0.23609532189713084,0.38723710682081225,-0.40156531384122846,1.1447500131709183,1.0701601286370668,-0.03766376468274858,-1.746524104659968,-1.5783139411225788,1.4995670283946096,-0.6175661397525806,0.5258452995193653,1.3044639973832475,3.244826799017829,-0.8214623601730139,1.6992696820323683,0.6601814574178648,0.8224740869191085,0.5087582951969946,0.8065146214158287,0.11485486211702632,2.8458055936098234,1.332880448717388,-0.4226942464977029,4.492615277702867,1.1001502232099265,0.8857323527866384,0.05828124665914992,-0.6620681262993946,5.159139452386764,1.8901336133115505,-0.5735093847387928,-0.23609532189713084,1.4447157506111374,1.2325959289574466,1.4722284064322555
| 2,701
|
Arthritis
| 11
| 35
| 2.962199
| 0.003054
|
P28070,P61619,O75844,Q96HY6,P04062,P21964,Q14739,Q14108,P02545,Q13510,O15460
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
258,169,43,270,177,82,53,21,214,119,312
|
1306,312,43,1669,214,177,1075,1598,563,1951,716,82,2427,258,812,1187,813,1477,1992,1316,169,1219,119,21,53,1127,1755,2089,738,2525,1485,270,360,806,1239
|
-0.11596206747168612,1.1001502232099265,2.734822878575379,-0.33878127776425015,1.4308934785310223,1.5805599528095038,0.03925969392486323,-0.2974182770678407,0.559819657694308,-0.5082402040270202,0.351885919191322,2.2367341600459416,-0.9628253083803223,1.2901855033977274,0.2622351395530162,-0.03766376468274858,0.2622351395530162,-0.21584326062426626,-0.5298892096352652,-0.11596206747168612,1.6469125414193932,-0.05710757719101301,1.951920624080694,3.1159288248830843,2.5574259051028014,0.000966854535827841,-0.3805374686703146,-0.5954826549590951,0.3341023914526849,-1.1336777677321255,-0.21584326062426626,1.2614864555637981,0.9635315701724516,0.28031310881637544,-0.05710757719101301
| 2,701
|
Slc mediated transmembrane transport
| 14
| 22
| 2.902443
| 0.003703
|
Q96QD8,P12236,P35613,Q8TB61,Q9H2H9,Q70HW3,O00400,P36404,Q9Y6M7,Q9UBX3,Q99808,P53985,P11166,Q8NEW0
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
389,415,381,136,138,11,170,366,143,47,338,254,222,95
|
170,462,605,1044,222,750,415,1283,381,366,254,839,1191,11,95,136,389,338,138,47,681,143
|
1.6337233768883894,0.7258267538427401,0.49160405626708076,0.05828124665914992,1.4031156606893533,0.31624613864460677,0.8224740869191085,-0.09625596283480581,0.9014040733816177,0.9480828206502808,1.3044639973832475,0.24408206050486364,-0.03766376468274858,3.617915206963102,2.1203470954716264,1.8526312438376766,0.8857323527866384,1.0399612405003023,1.8400575311170198,2.6626661752675664,0.4048059034205665,1.802114682609706
| 2,701
|
Vascular process in circulatory system
| 13
| 31
| 2.873672
| 0.004057
|
P41440,Q96QD8,Q9H2H9,Q15149,Q99808,Q01469,P08183,Q9HB40,O15439,P53985,P33527,P11166,P42892
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
321,389,138,198,338,51,180,256,248,254,348,222,155
|
1523,248,414,2517,808,1411,180,222,980,1024,699,348,321,155,1985,1445,254,51,2433,1890,2287,198,839,1191,1901,389,338,138,256,1462,681
|
-0.25644127155135765,1.3186955452496854,0.8224740869191085,-1.1336777677321255,0.2622351395530162,-0.1756174312141384,1.5537307142177417,1.4031156606893533,0.11485486211702632,0.07722049678650203,0.36959730040846983,0.9942651268493035,1.085181098032962,1.7122602692585014,-0.5298892096352652,-0.19568424190462033,1.3044639973832475,2.568067202131094,-0.9628253083803223,-0.4652592172226013,-0.7753301127313307,1.4859193366122214,0.24408206050486364,-0.03766376468274858,-0.4652592172226013,0.8857323527866384,1.0399612405003023,1.8400575311170198,1.3044639973832475,-0.19568424190462033,0.4048059034205665
| 2,701
|
Cation transmembrane transporter activity
| 37
| 68
| 2.842285
| 0.004479
|
P00403,Q96ES6,Q96QD8,Q9Y487,Q9H2H9,Q70HW3,Q9Y6M7,O43808,P51790,Q7KZN9,O95202,P56385,P61619,P10606,O00400,Q96NB2,P98194,Q9UM00,Q9Y5K8,Q9HD20,O75964,P07355,Q8N4V1,Q99808,P31930,Q96ER9,Q13423,P13073,Q93050,Q9HC21,Q8NEW0,Q9BXP2,O43772,Q9H0U3,P05023,Q9UDW1,P16615
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
251,128,389,134,138,11,143,147,280,152,405,407,169,298,170,176,178,318,452,58,57,313,70,338,81,468,340,343,91,220,95,359,103,238,243,118,252
|
170,103,147,2015,57,405,251,243,1118,605,1568,313,2212,1044,749,298,750,343,252,1024,1076,1343,1602,699,622,2337,81,1777,1882,2191,2573,2574,280,2306,407,471,169,178,551,340,839,518,11,152,70,598,95,1426,91,468,128,176,389,338,359,238,138,630,220,58,118,1433,318,681,134,452,933,143
|
1.6337233768883894,2.060949321084514,1.7638347606018192,-0.5516452556198194,2.5038189105500694,0.8383751777967641,1.3044639973832475,1.332880448717388,0.000966854535827841,0.49160405626708076,-0.27688196692354466,1.1001502232099265,-0.707024253971549,0.05828124665914992,0.31624613864460677,1.1447500131709183,0.31624613864460677,1.0095506891404633,1.3044639973832475,0.07722049678650203,0.03925969392486323,-0.1357571511500396,-0.2974182770678407,0.36959730040846983,0.47438206198749655,-0.8447106696636559,2.248201202031891,-0.40156531384122846,-0.4652592172226013,-0.6844888552895658,-1.234355168597917,-1.234355168597917,1.203511402271728,-0.7983359233670255,0.8383751777967641,0.7095080229146791,1.6469125414193932,1.5805599528095038,0.5767080236830171,1.0247826043693027,0.24408206050486364,0.6269838228448695,3.617915206963102,1.7381246312443195,2.3723562686361177,0.5087582951969946,2.1203470954716264,-0.1756174312141384,2.1672811097819484,0.7258267538427401,1.9025621688075542,1.5939123156550052,0.8857323527866384,1.0399612405003023,0.9635315701724516,1.3470190066264098,1.8400575311170198,0.47438206198749655,1.417026875112562,2.5038189105500694,1.9763891703113325,-0.1756174312141384,1.1001502232099265,0.4048059034205665,1.8901336133115505,0.7582817372111945,0.17070624531058928,1.802114682609706
| 2,701
|
Basolateral plasma membrane
| 18
| 42
| 2.830612
| 0.004646
|
P41440,Q14254,P58107,Q9H2H9,P35222,P15924,Q9Y6M7,P04920,Q99808,P53985,P05023,O15439,O75955,P57105,P33527,P11166,P07355,P35613
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
321,383,101,138,73,14,143,462,338,254,243,248,495,315,348,222,313,381
|
1465,1069,248,495,937,808,890,462,243,1118,313,1044,960,222,1530,1245,1634,14,1701,1024,699,1879,348,73,381,321,254,624,315,101,677,1890,529,1784,1785,1891,383,338,2156,138,681,143
|
-0.21584326062426626,0.03925969392486323,1.3186955452496854,0.6601814574178648,0.15216824938562942,0.2622351395530162,0.18916598311737365,0.7258267538427401,1.332880448717388,0.000966854535827841,1.1001502232099265,0.05828124665914992,0.13355134211590133,1.4031156606893533,-0.25644127155135765,-0.07663805632366444,-0.3180510829696362,3.3434324737059566,-0.3596097669606752,0.07722049678650203,0.36959730040846983,-0.4652592172226013,0.9942651268493035,2.3276237027439657,0.9014040733816177,1.085181098032962,1.3044639973832475,0.47438206198749655,1.1001502232099265,2.072894727430521,0.4048059034205665,-0.4652592172226013,0.6102896170952945,-0.40156531384122846,-0.40156531384122846,-0.4652592172226013,0.9014040733816177,1.0399612405003023,-0.6397609283995005,1.8400575311170198,0.4048059034205665,1.802114682609706
| 2,701
|
Steroid binding
| 11
| 20
| 2.821218
| 0.004784
|
O15173,O15118,P30536,P61916,P04062,P38435,P05023,Q14108,Q9H4L5,P45880,P21796
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
127,130,195,72,177,114,243,21,153,28,62
|
308,130,127,794,1817,177,243,2212,62,797,1440,195,114,28,72,21,610,1688,1194,153
|
1.115067853889435,1.8901336133115505,1.9025621688075542,0.28031310881637544,-0.4226942464977029,1.5805599528095038,1.332880448717388,-0.707024253971549,2.460444745964291,0.28031310881637544,-0.19568424190462033,1.4995670283946096,2.0128330114691035,2.905147117866422,2.36121680514361,3.1159288248830843,0.49160405626708076,-0.33878127776425015,-0.03766376468274858,1.7381246312443195
| 2,701
|
Lipid droplet
| 10
| 27
| 2.816685
| 0.004852
|
Q9H6V9,Q07065,Q9H8H3,P48449,O43760,Q01105,Q8NF37,Q8NBX0,P07355,P51572
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
96,263,71,83,52,88,184,59,313,253
|
1241,52,1309,1377,1437,1696,892,313,83,773,774,253,2341,88,263,594,1456,59,184,358,690,501,96,71,641,1372,710
|
-0.07663805632366444,2.5574259051028014,-0.11596206747168612,-0.1556420051329787,-0.19568424190462033,-0.3596097669606752,0.18916598311737365,1.1001502232099265,2.2367341600459416,0.2983165752789475,0.2983165752789475,1.3044639973832475,-0.8447106696636559,2.1672811097819484,1.2758597586554565,0.5087582951969946,-0.19568424190462033,2.48218674176581,1.540253330753097,0.9635315701724516,0.38723710682081225,0.6601814574178648,2.1203470954716264,2.3723562686361177,0.4570917855835725,-0.1357571511500396,0.36959730040846983
| 2,701
|
Respirasome
| 17
| 40
| 2.810316
| 0.004949
|
P00403,P14406,O96000,O14949,O43676,Q9P0J0,O95169,Q6DKK2,O95168,Q86Y39,P10606,P31930,Q13423,Q9UDW1,Q7KZN9,P21912,Q9Y6M9
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
251,1,290,65,4,133,295,102,325,104,298,81,340,118,152,314,30
|
2556,1115,65,4,1973,2516,478,1528,2230,325,295,2442,2017,290,251,749,1950,298,343,1,1471,2561,1076,314,569,2046,2397,81,2608,1256,340,399,609,102,152,104,133,118,617,30
|
-1.2089703136081216,0.000966854535827841,2.4276234185896435,4.14073910845815,-0.5298892096352652,-1.1336777677321255,0.6931278673873417,-0.25644127155135765,-0.7296754780456444,1.0701601286370668,1.1595152238833708,-0.9868321395764779,-0.5516452556198194,1.1742303044100273,1.3044639973832475,0.31624613864460677,-0.5082402040270202,1.1447500131709183,1.0095506891404633,5.210648084460358,-0.21584326062426626,-1.2089703136081216,0.03925969392486323,1.1001502232099265,0.5428655840352268,-0.5735093847387928,-0.9151995911546438,2.248201202031891,-1.3635087831226131,-0.07663805632366444,1.0247826043693027,0.8542183112675076,0.49160405626708076,2.072894727430521,1.7381246312443195,2.060949321084514,1.8901336133115505,1.9763891703113325,0.49160405626708076,2.8557533308424374
| 2,701
|
Mitochondrial protein import
| 16
| 34
| 2.803135
| 0.005061
|
Q10713,Q9NS69,Q99595,Q13505,Q9BVV7,Q3ZCQ8,P12236,O95169,O96008,O14925,Q9Y5J9,Q9Y5J7,Q9Y512,O75431,P21796,Q8N4H5
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
161,2,3,296,390,417,415,295,326,196,209,276,212,309,62,32
|
196,712,2394,309,1493,889,684,295,326,1568,749,2654,750,415,62,2337,2594,161,296,498,417,425,32,3,2552,390,2178,2,1335,666,617,212,276,209
|
1.4859193366122214,0.351885919191322,-0.9151995911546438,1.115067853889435,-0.23609532189713084,0.18916598311737365,0.38723710682081225,1.1595152238833708,1.0701601286370668,-0.27688196692354466,0.31624613864460677,-1.746524104659968,0.31624613864460677,0.8224740869191085,2.460444745964291,-0.8447106696636559,-1.3373751235719122,1.6992696820323683,1.1595152238833708,0.6601814574178648,0.8224740869191085,0.8065146214158287,2.8458055936098234,4.492615277702867,-1.183730197015092,0.8857323527866384,-0.6620681262993946,5.159139452386764,-0.11596206747168612,0.42230424858015453,0.49160405626708076,1.4447157506111374,1.2325959289574466,1.4722284064322555
| 2,701
|
primary active transporter
| 11
| 24
| 2.794654
| 0.005196
|
Q9NS69,O96008,Q9BUN8,Q96NB2,Q9Y5J7,P98194,P05023,Q6P4A7,Q6NTF9,P16615,Q8N4H5
|
Functions
|
Panther Protein class
|
panther_protein_class
|
2,326,110,176,276,178,243,120,156,252,32
|
2424,339,684,326,243,1118,1177,252,1024,699,624,178,498,839,156,120,32,1296,176,110,630,2178,2,276
|
-0.9628253083803223,1.0247826043693027,0.38723710682081225,1.0701601286370668,1.332880448717388,0.000966854535827841,-0.03766376468274858,1.3044639973832475,0.07722049678650203,0.36959730040846983,0.47438206198749655,1.5805599528095038,0.6601814574178648,0.24408206050486364,1.7122602692585014,1.951920624080694,2.8458055936098234,-0.09625596283480581,1.5939123156550052,2.0489706294219476,0.47438206198749655,-0.6620681262993946,5.159139452386764,1.2325959289574466
| 2,701
|
Proton transmembrane transporter activity
| 16
| 34
| 2.762658
| 0.005733
|
P00403,Q96ES6,P51790,Q93050,Q9Y487,P10606,O00400,Q9Y5K8,P31930,Q13423,Q9UDW1,P13073,Q7KZN9,O95202,P56385,O75964
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
251,128,280,91,134,298,170,452,81,340,118,343,152,405,407,57
|
170,2015,57,405,251,605,1568,749,298,750,343,1076,1343,1602,622,2337,81,1777,1882,2191,2573,280,2306,407,471,551,340,152,91,128,118,1433,134,452
|
1.6337233768883894,-0.5516452556198194,2.5038189105500694,0.8383751777967641,1.3044639973832475,0.49160405626708076,-0.27688196692354466,0.31624613864460677,1.1447500131709183,0.31624613864460677,1.0095506891404633,0.03925969392486323,-0.1357571511500396,-0.2974182770678407,0.47438206198749655,-0.8447106696636559,2.248201202031891,-0.40156531384122846,-0.4652592172226013,-0.6844888552895658,-1.234355168597917,1.203511402271728,-0.7983359233670255,0.8383751777967641,0.7095080229146791,0.5767080236830171,1.0247826043693027,1.7381246312443195,2.1672811097819484,1.9025621688075542,1.9763891703113325,-0.1756174312141384,1.8901336133115505,0.7582817372111945
| 2,701
|
Protein localization to mitochondrion
| 22
| 51
| 2.742689
| 0.006094
|
Q9NS69,Q99595,Q9P0J0,Q9BVV7,Q8WWC4,P55786,Q9Y5J7,Q8N4H5,Q10713,Q3ZCQ8,O95831,Q5JRX3,Q15070,Q99797,P30536,O96008,O14925,Q9Y5J9,Q9Y512,Q9Y6C9,Q8TB36,P51572
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,3,133,390,140,17,276,32,161,417,297,425,56,317,195,326,196,209,212,92,244,253
|
1306,696,434,826,196,712,1493,684,1771,297,326,1176,2654,939,1246,2636,1497,195,1853,636,2110,583,253,870,17,2319,161,56,498,417,596,425,992,32,244,140,1839,3,317,390,1059,2178,2,133,2069,617,1522,212,276,209,92
|
-0.11596206747168612,0.36959730040846983,0.7744188751377666,0.24408206050486364,1.4859193366122214,0.351885919191322,-0.23609532189713084,0.38723710682081225,-0.40156531384122846,1.1447500131709183,1.0701601286370668,-0.03766376468274858,-1.746524104659968,0.15216824938562942,-0.07663805632366444,-1.5783139411225788,-0.23609532189713084,1.4995670283946096,-0.4439252239854569,0.4570917855835725,-0.6175661397525806,0.5258452995193653,1.3044639973832475,0.20754810800791113,3.244826799017829,-0.8214623601730139,1.6992696820323683,2.5360636019540204,0.6601814574178648,0.8224740869191085,0.5087582951969946,0.8065146214158287,0.11485486211702632,2.8458055936098234,1.332880448717388,1.8147994633249862,-0.4226942464977029,4.492615277702867,1.1001502232099265,0.8857323527866384,0.05828124665914992,-0.6620681262993946,5.159139452386764,1.8901336133115505,-0.5735093847387928,0.49160405626708076,-0.23609532189713084,1.4447157506111374,1.2325959289574466,1.4722284064322555,2.1555955949755234
| 2,701
|
Organic acid transmembrane transporter activity
| 12
| 21
| 2.734258
| 0.006252
|
O15439,P41440,Q96QD8,Q9H2H9,Q9UBX3,Q96NB2,Q9BQT8,P08183,Q9H2D1,Q02978,P53985,P33527
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
248,321,389,138,47,176,50,180,22,183,254,348
|
248,889,435,180,1044,348,321,254,183,839,1191,176,389,50,22,138,630,47,666,681,933
|
1.3186955452496854,0.18916598311737365,0.7744188751377666,1.5537307142177417,0.05828124665914992,0.9942651268493035,1.085181098032962,1.3044639973832475,1.540253330753097,0.24408206050486364,-0.03766376468274858,1.5939123156550052,0.8857323527866384,2.578682101820039,3.1065707089213883,1.8400575311170198,0.47438206198749655,2.6626661752675664,0.42230424858015453,0.4048059034205665,0.17070624531058928
| 2,701
|
Lysosome
| 12
| 45
| 2.727845
| 0.006375
|
P07602,O15118,P17900,Q9Y487,P61916,P10619,P50897,P11279,Q9NZJ7,Q14108,Q13510,Q93050
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
31,130,163,134,72,168,74,80,146,21,119,91
|
696,1307,1524,319,130,536,1376,590,177,1022,1075,1281,31,829,342,2188,698,508,168,673,80,1601,1851,809,163,1314,2509,74,464,471,72,1611,1450,119,21,436,2472,1484,91,2126,788,146,1433,886,134
|
0.36959730040846983,-0.11596206747168612,-0.25644127155135765,1.085181098032962,1.8901336133115505,0.593531179510868,-0.1556420051329787,0.5087582951969946,1.5805599528095038,0.07722049678650203,0.03925969392486323,-0.09625596283480581,2.8458055936098234,0.24408206050486364,1.0095506891404633,-0.6844888552895658,0.36959730040846983,0.6436142777409396,1.6469125414193932,0.4048059034205665,2.248201202031891,-0.2974182770678407,-0.4439252239854569,0.2622351395530162,1.6862398498357258,-0.11596206747168612,-1.1088623151263601,2.3163672654572762,0.7258267538427401,0.7095080229146791,2.36121680514361,-0.2974182770678407,-0.19568424190462033,1.951920624080694,3.1159288248830843,0.7744188751377666,-1.035240699093695,-0.21584326062426626,2.1672811097819484,-0.6175661397525806,0.2983165752789475,1.7766325496335293,-0.1756174312141384,0.20754810800791113,1.8901336133115505
| 2,701
|
Protein insertion into membrane
| 10
| 28
| 2.70109
| 0.006911
|
Q9NS69,Q9P0J0,Q8N4V1,P61619,Q15629,Q8WWC4,Q96A33,Q9Y5J9,Q9Y512,Q15070
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,133,70,169,41,140,236,209,212,56
|
826,1767,536,1489,684,1176,1497,2110,1210,169,2145,56,41,596,465,2691,70,660,140,236,692,2,1197,133,617,212,276,209
|
0.24408206050486364,-0.40156531384122846,0.593531179510868,-0.23609532189713084,0.38723710682081225,-0.03766376468274858,-0.23609532189713084,-0.6175661397525806,-0.05710757719101301,1.6469125414193932,-0.6397609283995005,2.5360636019540204,2.745032234471493,0.5087582951969946,0.7258267538427401,-2.878787438217548,2.3723562686361177,0.42230424858015453,1.8147994633249862,1.3470190066264098,0.38723710682081225,5.159139452386764,-0.03766376468274858,1.8901336133115505,0.49160405626708076,1.4447157506111374,1.2325959289574466,1.4722284064322555
| 2,701
|
Secretory granule membrane
| 30
| 62
| 2.695711
| 0.007024
|
Q07065,Q08554,Q4KMQ2,Q96JJ7,P15924,Q9NZJ7,P49755,P20073,O15260,P07602,O95721,P61106,Q709C8,Q01469,O00264,Q969Q5,Q8NF37,Q9Y5K8,Q6IAA8,P30519,P11279,Q93050,Q15363,Q08722,Q9H0U3,P42785,O15439,P10253,Q14254,P35613
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
263,5,518,271,14,146,277,406,285,31,538,416,173,51,308,311,184,452,446,66,80,91,349,354,238,109,248,508,383,381
|
863,308,1145,285,248,2209,1175,867,1469,713,538,31,508,563,80,1601,14,406,66,1283,1822,381,1078,109,985,277,2574,773,774,1674,1639,416,1213,1929,1125,51,263,5,354,2028,1544,1053,383,349,518,1226,446,173,184,921,599,91,311,271,2326,788,238,641,146,1168,452,2249
|
0.20754810800791113,1.115067853889435,-0.01830586786658518,1.1888955874119858,1.3186955452496854,-0.707024253971549,-0.03766376468274858,0.20754810800791113,-0.21584326062426626,0.351885919191322,0.593531179510868,2.8458055936098234,0.6436142777409396,0.559819657694308,2.248201202031891,-0.2974182770678407,3.3434324737059566,0.8383751777967641,2.416626861835804,-0.09625596283480581,-0.4226942464977029,0.9014040733816177,0.03925969392486323,2.0489706294219476,0.11485486211702632,1.2180780751359057,-1.234355168597917,0.2983165752789475,0.2983165752789475,-0.33878127776425015,-0.3180510829696362,0.8224740869191085,-0.05710757719101301,-0.4866972109565579,0.000966854535827841,2.568067202131094,1.2758597586554565,4.051729415764505,0.9789255457318856,-0.5516452556198194,-0.25644127155135765,0.05828124665914992,0.9014040733816177,0.9942651268493035,0.6269838228448695,-0.05710757719101301,0.7582817372111945,1.6072235088664195,1.540253330753097,0.17070624531058928,0.5087582951969946,2.1672811097819484,1.115067853889435,1.2614864555637981,-0.8214623601730139,0.2983165752789475,1.3470190066264098,0.4570917855835725,1.7766325496335293,-0.01830586786658518,0.7582817372111945,-0.7296754780456444
| 2,701
|
Multicellular organismal signaling
| 7
| 22
| 2.666422
| 0.007666
|
Q15149,O75844,P15924,Q6PI78,P14923,P04062,P05023
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
198,43,14,206,16,177,243
|
1001,43,177,243,1118,16,14,252,685,1024,1740,699,1283,912,832,2114,677,1784,1159,198,206,1755
|
0.0960781397108018,2.734822878575379,1.5805599528095038,1.332880448717388,0.000966854535827841,3.2538860606266975,3.3434324737059566,1.3044639973832475,0.38723710682081225,0.07722049678650203,-0.3805374686703146,0.36959730040846983,-0.09625596283480581,0.17070624531058928,0.24408206050486364,-0.6175661397525806,0.4048059034205665,-0.40156531384122846,-0.01830586786658518,1.4859193366122214,1.4722284064322555,-0.3805374686703146
| 2,701
|
Glycerolipid biosynthetic process
| 20
| 35
| 2.66559
| 0.007685
|
O14735,Q92643,Q96BW9,Q10713,O15228,Q9NX62,O95674,Q9NTJ5,P48651,Q01469,Q8NF37,Q8WTV0,Q9BTU6,Q6P1A2,Q6IAN0,Q9NPH0,Q92604,Q9UG56,Q6UWP7,P35790
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
642,287,679,161,289,559,172,694,175,51,184,322,324,586,585,207,232,361,626,365
|
1523,642,289,1437,172,1248,365,983,175,51,1219,2144,161,2461,585,586,626,2472,184,322,902,232,287,679,1486,1300,926,1585,324,1842,207,693,694,559,361
|
-0.25644127155135765,0.439732694154855,1.1742303044100273,-0.19568424190462033,1.6072235088664195,-0.07663805632366444,0.9480828206502808,0.11485486211702632,1.5939123156550052,2.568067202131094,-0.05710757719101301,-0.6397609283995005,1.6992696820323683,-1.0109701322777465,0.5258452995193653,0.5258452995193653,0.47438206198749655,-1.035240699093695,1.540253330753097,1.085181098032962,0.18916598311737365,1.3611115149729005,1.1888955874119858,0.4048059034205665,-0.21584326062426626,-0.09625596283480581,0.17070624531058928,-0.27688196692354466,1.085181098032962,-0.4226942464977029,1.4722284064322555,0.38723710682081225,0.38723710682081225,0.5767080236830171,0.9635315701724516
| 2,701
|
Ion transmembrane transporter activity
| 56
| 98
| 2.662253
| 0.007762
|
P00403,Q96ES6,Q96QD8,Q9Y487,Q8TB61,Q9H2H9,Q70HW3,Q9Y6M7,O43808,Q9H2D1,Q7KZN9,P51790,O95202,P56385,P45880,P12236,Q9Y277,P61619,P10606,O00400,Q9UBX3,Q96NB2,Q9BQT8,P98194,O95563,Q02978,O75964,Q9HD20,Q9UM00,Q9Y5K8,P21796,P07355,P41440,Q8N4V1,P04920,Q99808,P31930,Q13423,Q96ER9,P13073,Q6NUK1,Q93050,Q9HC21,P33527,Q9C0H2,Q8NEW0,P11166,Q9BXP2,O43772,Q9H0U3,P05023,Q9UDW1,Q6P4A7,O15439,P53985,P16615
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
251,128,389,134,136,138,11,143,147,22,152,280,405,407,28,415,166,169,298,170,47,176,50,178,435,183,57,58,318,452,62,313,321,70,462,338,81,340,468,343,344,91,220,348,94,95,222,359,103,238,243,118,120,248,254,252
|
2227,170,248,536,103,147,889,2015,57,405,435,251,462,243,1118,605,1568,313,2212,1044,749,298,222,750,415,343,252,1024,1076,1343,1602,62,699,622,2337,81,348,1777,1882,2191,321,28,2573,2574,280,813,254,2306,407,471,169,178,551,183,340,2198,839,518,1961,344,1191,120,11,152,70,598,95,136,1836,1426,91,468,128,176,389,566,338,50,359,94,238,22,138,630,220,58,47,118,1433,666,318,166,681,134,452,933,2099,143
|
-0.7296754780456444,1.6337233768883894,1.3186955452496854,0.593531179510868,2.060949321084514,1.7638347606018192,0.18916598311737365,-0.5516452556198194,2.5038189105500694,0.8383751777967641,0.7744188751377666,1.3044639973832475,0.7258267538427401,1.332880448717388,0.000966854535827841,0.49160405626708076,-0.27688196692354466,1.1001502232099265,-0.707024253971549,0.05828124665914992,0.31624613864460677,1.1447500131709183,1.4031156606893533,0.31624613864460677,0.8224740869191085,1.0095506891404633,1.3044639973832475,0.07722049678650203,0.03925969392486323,-0.1357571511500396,-0.2974182770678407,2.460444745964291,0.36959730040846983,0.47438206198749655,-0.8447106696636559,2.248201202031891,0.9942651268493035,-0.40156531384122846,-0.4652592172226013,-0.6844888552895658,1.085181098032962,2.905147117866422,-1.234355168597917,-1.234355168597917,1.203511402271728,0.2622351395530162,1.3044639973832475,-0.7983359233670255,0.8383751777967641,0.7095080229146791,1.6469125414193932,1.5805599528095038,0.5767080236830171,1.540253330753097,1.0247826043693027,-0.6844888552895658,0.24408206050486364,0.6269838228448695,-0.5082402040270202,1.0095506891404633,-0.03766376468274858,1.951920624080694,3.617915206963102,1.7381246312443195,2.3723562686361177,0.5087582951969946,2.1203470954716264,1.8526312438376766,-0.4226942464977029,-0.1756174312141384,2.1672811097819484,0.7258267538427401,1.9025621688075542,1.5939123156550052,0.8857323527866384,0.559819657694308,1.0399612405003023,2.578682101820039,0.9635315701724516,2.1321287594832308,1.3470190066264098,3.1065707089213883,1.8400575311170198,0.47438206198749655,1.417026875112562,2.5038189105500694,2.6626661752675664,1.9763891703113325,-0.1756174312141384,0.42230424858015453,1.1001502232099265,1.6862398498357258,0.4048059034205665,1.8901336133115505,0.7582817372111945,0.17070624531058928,-0.5954826549590951,1.802114682609706
| 2,701
|
Endoplasmic reticulum golgi intermediate compartment
| 20
| 41
| 2.641429
| 0.008256
|
P24390,Q5VYK3,P49755,O15258,O15260,O95070,Q9Y3A6,Q9BVK6,Q9Y3B3,Q9Y282,Q15904,Q10472,Q13190,Q7Z7H5,Q15363,Q92538,Q9Y678,P80303,Q02818,P51572
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
9,530,277,523,285,159,430,174,302,54,436,456,215,219,349,358,106,116,124,253
|
523,285,865,619,159,979,2559,9,2356,1498,583,277,2219,253,1674,1257,541,116,124,456,801,215,1354,1013,349,436,530,219,1106,358,2202,1516,174,1663,765,2555,54,430,302,106,711
|
0.6102896170952945,1.1888955874119858,0.20754810800791113,0.47438206198749655,1.6992696820323683,0.11485486211702632,-1.2089703136081216,3.6674600654956833,-0.8680821176442824,-0.23609532189713084,0.5258452995193653,1.2180780751359057,-0.707024253971549,1.3044639973832475,-0.33878127776425015,-0.07663805632366444,0.593531179510868,1.9763891703113325,1.9273121495158725,0.742084510223003,0.28031310881637544,1.4308934785310223,-0.1357571511500396,0.0960781397108018,0.9942651268493035,0.7744188751377666,0.6102896170952945,1.417026875112562,0.02015513431309902,0.9635315701724516,-0.6844888552895658,-0.23609532189713084,1.6072235088664195,-0.3180510829696362,0.31624613864460677,-1.183730197015092,2.5574259051028014,0.8065146214158287,1.1447500131709183,2.060949321084514,0.36959730040846983
| 2,701
|
Carbohydrate derivative transport
| 13
| 18
| 2.638554
| 0.008326
|
O15439,P07602,Q8WTV0,Q08722,P41440,P61916,Q8TB61,O00400,Q99808,Q9NZJ7,O43808,Q6NUK1,Q9HC21
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
248,31,322,354,321,72,136,170,338,146,147,344,220
|
825,170,248,147,605,31,750,415,321,72,354,344,136,1836,322,338,220,146
|
0.24408206050486364,1.6337233768883894,1.3186955452496854,1.7638347606018192,0.49160405626708076,2.8458055936098234,0.31624613864460677,0.8224740869191085,1.085181098032962,2.36121680514361,0.9789255457318856,1.0095506891404633,1.8526312438376766,-0.4226942464977029,1.085181098032962,1.0399612405003023,1.417026875112562,1.7766325496335293
| 2,701
|
Intrinsic component of organelle membrane
| 73
| 111
| 2.631833
| 0.008493
|
O15118,Q99595,Q16891,Q9NZ01,Q8TB61,Q9HCU5,O95470,Q5XKP0,O43808,O15258,Q12981,Q9Y2R0,Q92643,Q8IWA4,Q6NTF9,O95070,P42892,Q9UBM7,Q16611,Q13505,Q9UKV5,P61619,Q15629,O75844,Q00325,Q96NB2,P98194,Q9UH99,Q14739,P10321,Q9Y282,Q9BUR5,Q9Y4P3,Q15070,O75431,Q86XL3,Q9UM00,P57105,O95563,P17152,P27824,Q6UXV4,Q8N4V1,O96008,O14925,Q53H12,Q9P035,O00767,Q9Y512,Q8NE86,Q5J8M3,Q96ER9,Q9Y4W6,Q9NVH1,Q9HC21,Q9H3K2,P57088,O43505,Q16134,O75880,Q9UG56,Q8TCT8,Q9BUN8,Q96A33,Q9BTV4,Q9H9B4,Q8TB36,Q8TCT9,Q8N2H4,Q15388,Q6P4A7,Q9NQC3,P51572
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
130,3,388,6,136,534,144,273,147,523,543,24,287,545,156,159,155,36,37,296,560,169,41,43,551,176,178,440,53,563,54,186,579,56,309,187,318,315,435,320,570,200,70,326,196,596,208,335,212,598,465,468,469,475,220,223,227,353,608,604,361,250,110,236,488,630,244,112,115,498,120,122,253
|
1277,825,335,196,130,1145,523,1767,353,147,309,43,604,620,684,159,144,435,326,2105,563,750,320,1024,1671,2356,570,2262,2594,155,774,253,227,315,1639,169,178,551,1261,543,296,1751,53,2145,56,498,41,608,37,388,596,465,273,156,120,200,948,842,187,721,545,1017,1396,115,70,660,598,244,136,250,112,902,287,236,468,176,1300,3,906,927,488,928,110,186,1059,223,630,1661,220,534,692,122,475,1335,6,208,1197,1729,36,361,1065,440,560,318,54,24,806,579,469,212,710
|
-0.09625596283480581,0.24408206050486364,1.0399612405003023,1.4859193366122214,1.8901336133115505,-0.01830586786658518,0.6102896170952945,-0.40156531384122846,0.9789255457318856,1.7638347606018192,1.115067853889435,2.734822878575379,0.49160405626708076,0.47438206198749655,0.38723710682081225,1.6992696820323683,1.7893924505266094,0.7744188751377666,1.0701601286370668,-0.6175661397525806,0.559819657694308,0.31624613864460677,1.085181098032962,0.07722049678650203,-0.33878127776425015,-0.8680821176442824,0.5428655840352268,-0.7524437006538256,-1.3373751235719122,1.7122602692585014,0.2983165752789475,1.3044639973832475,1.3891595529580087,1.1001502232099265,-0.3180510829696362,1.6469125414193932,1.5805599528095038,0.5767080236830171,-0.07663805632366444,0.593531179510868,1.1595152238833708,-0.3805374686703146,2.5574259051028014,-0.6397609283995005,2.5360636019540204,0.6601814574178648,2.745032234471493,0.49160405626708076,2.775514718206515,0.8857323527866384,0.5087582951969946,0.7258267538427401,1.2470652835370355,1.7122602692585014,1.951920624080694,1.4859193366122214,0.15216824938562942,0.24408206050486364,1.526733762162025,0.351885919191322,0.593531179510868,0.0960781397108018,-0.1556420051329787,1.988571456222201,2.3723562686361177,0.42230424858015453,0.5087582951969946,1.332880448717388,1.8526312438376766,1.3186955452496854,2.0369584700842114,0.18916598311737365,1.1888955874119858,1.3470190066264098,0.7258267538427401,1.5939123156550052,-0.09625596283480581,4.492615277702867,0.18916598311737365,0.17070624531058928,0.676685832241666,0.17070624531058928,2.0489706294219476,1.540253330753097,0.05828124665914992,1.4031156606893533,0.47438206198749655,-0.3180510829696362,1.417026875112562,0.6102896170952945,0.38723710682081225,1.93963397583531,0.7095080229146791,-0.11596206747168612,3.953135916812116,1.4722284064322555,-0.03766376468274858,-0.3596097669606752,2.8057811853844417,0.9635315701724516,0.05828124665914992,0.7744188751377666,0.5767080236830171,1.1001502232099265,2.5574259051028014,2.973351412079002,0.28031310881637544,0.5428655840352268,0.7258267538427401,1.4447157506111374,0.36959730040846983
| 2,701
|
Abnormal circulating cholesterol concentration
| 13
| 29
| 2.631307
| 0.008506
|
P07602,Q15392,Q9UBM7,P37268,P61916,P50402,Q9BV10,Q9NZJ7,Q14739,Q15800,O75431,Q15904,P02545
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
31,131,36,69,72,197,237,146,53,409,309,436,214
|
309,214,938,31,69,2509,831,833,197,2575,835,72,1219,1261,1998,1860,53,131,594,409,436,2270,649,488,237,601,146,36,666
|
1.115067853889435,1.4308934785310223,0.15216824938562942,2.8458055936098234,2.3945487262934133,-1.1088623151263601,0.24408206050486364,0.24408206050486364,1.4859193366122214,-1.234355168597917,0.24408206050486364,2.36121680514361,-0.05710757719101301,-0.07663805632366444,-0.5298892096352652,-0.4439252239854569,2.5574259051028014,1.8901336133115505,0.5087582951969946,0.8383751777967641,0.7744188751377666,-0.7524437006538256,0.439732694154855,0.676685832241666,1.3470190066264098,0.5087582951969946,1.7766325496335293,2.8057811853844417,0.42230424858015453
| 2,701
|
Subsets and Splits
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