term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abnormality of the wrist
| 9
| 27
| 2.451176
| 0.014239
|
Q8WVQ1,Q15125,O95831,Q13510,Q7RTS9,O75844,P16278,Q9BV10,Q9H6K4
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
199,11,237,46,239,80,54,248,93
|
2871,1353,2102,2853,80,1783,237,977,54,265,3133,893,2925,1824,1869,912,2248,46,2637,11,1010,239,199,248,93,3189,2581
|
-0.9233040534854985,0.06905820401443656,-0.33362432918571483,-0.900491564579252,2.4499538883891847,-0.18172843641255768,1.4589593479977,0.3347961754544072,2.712662399939541,1.367421765529877,-1.3860262152164,0.3980834008801064,-0.9926104125098789,-0.20035758061349548,-0.21908700961772024,0.3823733530740993,-0.41211517468133246,2.792690291492383,-0.7013933032185452,3.424342931133359,0.31878600721311506,1.4589593479977,1.6236237566684577,1.4249475180109552,2.3595270048660506,-1.6270001302540178,-0.6373991838940739
| 3,282
|
Active ion transmembrane transporter activity
| 23
| 42
| 2.443668
| 0.014539
|
P16615,O95202,P08195,P21281,P98194,P13073,P20674,Q9Y6M7,Q9H2J7,O14548,P55011,P00403,O43826,P41440,Q9HD20,P36543,P23634,Q9UDW1,P51798,P51790,P06576,P20020,P12236
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
384,394,270,778,407,153,663,416,424,793,293,292,303,438,188,693,565,68,583,331,205,618,378
|
793,303,394,292,810,1117,853,205,270,1254,2211,1255,378,153,2919,384,618,663,778,3176,565,2920,693,1789,438,1866,331,583,1481,293,1825,407,1550,1003,1012,424,1405,188,68,1690,945,416
|
0.47554353945259714,1.2127112505391577,1.0112796586421209,1.2370139309648251,0.46019487053471625,0.23757265698845073,0.4292836766633106,1.6021706965552707,1.3323904602126717,0.13746944516855703,-0.3923277640646288,0.13746944516855703,1.0371659946513645,1.918812369361769,-0.9926104125098789,1.0242489935338948,0.6543867400016848,0.5958417361485769,0.4908216973007541,-1.5721074020422647,0.7119066464917171,-0.9926104125098789,0.5661746186246456,-0.18172843641255768,0.9189967934039461,-0.21908700961772024,1.1511243328250194,0.6976210318395957,-0.0007502583674914466,1.2370139309648251,-0.20035758061349548,0.9982576128879851,-0.03619440570372816,0.31878600721311506,0.31878600721311506,0.9720538608178498,0.05173904046404934,1.6870955164987091,2.592048628230388,-0.1081959375724667,0.36658921531116717,0.9851824752695442
| 3,282
|
Entry into host
| 8
| 31
| 2.44191
| 0.01461
|
Q14108,P08195,Q8WTV0,P02786,Q9BTY2,P07858,P35613,Q9UPT5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,270,49,240,151,53,312,375
|
2171,892,417,1937,3167,240,1601,661,1941,53,270,2935,1785,978,2212,2375,1545,312,1388,1994,1795,1294,3,1960,650,49,750,575,151,375,2136
|
-0.37265087688372656,0.3980834008801064,0.9720538608178498,-0.25685057969960273,-1.544956106951877,1.4476634061842635,-0.07200734605445942,0.5958417361485769,-0.25685057969960273,2.712662399939541,1.3323904602126717,-1.0160076287643969,-0.18172843641255768,0.3347961754544072,-0.3923277640646288,-0.4923924005392478,-0.03619440570372816,1.2004894005422622,0.05173904046404934,-0.27588668305362396,-0.18172843641255768,0.12049491179844807,3.4972936020541496,-0.25685057969960273,0.6105758605037124,2.749321615614043,0.5211687621279207,0.7119066464917171,1.9284939850101928,1.0500310352209634,-0.33362432918571483
| 3,282
|
Amino acid transport
| 15
| 25
| 2.440391
| 0.014671
|
Q96H78,Q9H2J7,Q8IWT6,Q9UJS0,P55011,Q8TDW0,Q6P4A7,P30825,O75915,Q7L0J3,P08195,Q96NB2,O60831,Q9Y619,Q15041
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
34,424,325,659,293,585,230,138,484,332,270,503,528,60,569
|
2686,3005,528,794,484,1601,270,1735,138,293,2962,569,1460,650,230,332,325,585,34,503,424,1405,752,659,60
|
-0.7446984489999219,-1.1111173323671646,0.7684328524082645,0.47554353945259714,0.8377388499606527,-0.07200734605445942,1.3323904602126717,-0.144767223042154,1.9954018657539796,1.2370139309648251,-1.0395551932285616,0.7119066464917171,0.01683561215363658,0.6105758605037124,1.4814285535206084,1.1511243328250194,1.1759030599472666,0.6976210318395957,2.939384808405215,0.8101935073071703,0.9720538608178498,0.05173904046404934,0.5211687621279207,0.6105758605037124,2.682987626080082
| 3,282
|
Alcohol biosynthetic process
| 11
| 38
| 2.425244
| 0.015298
|
O15269,Q14739,Q15392,P00374,Q15125,Q13510,Q9UBM7,P04062,Q15800,Q16850,P37268
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
257,69,135,7,11,46,176,145,89,183,31
|
3119,257,1380,2720,405,1783,7,2763,145,2816,1659,833,265,2608,2331,648,31,2959,418,1954,3052,2081,2111,2146,1313,46,2942,69,11,2860,135,1917,89,841,183,3254,2480,176
|
-1.360179198444861,1.390559620323408,0.05173904046404934,-0.7665478813310426,0.9982576128879851,-0.18172843641255768,3.4750606508530564,-0.8106475789227858,1.9573524101711695,-0.8552914666396761,-0.1081959375724667,0.4447751115533682,1.367421765529877,-0.6799348090885988,-0.4721516811947069,0.6105758605037124,2.9529597638291984,-1.0395551932285616,0.9720538608178498,-0.25685057969960273,-1.184096314811162,-0.3142725349731669,-0.33362432918571483,-0.3530834233869732,0.10343536726148002,2.792690291492383,-1.0160076287643969,2.576604864876466,3.424342931133359,-0.900491564579252,2.0142460639311266,-0.23791768452069523,2.3927379782175318,0.4447751115533682,1.7183433107459631,-2.4223383762478106,-0.553816606593548,1.769720066961587
| 3,282
|
Glycosaminoglycan metabolism
| 8
| 14
| 2.422971
| 0.015394
|
Q8NCH0,P15586,O43505,Q8TB61,P06865,P16278,P54802,Q7LGA3
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
65,258,168,139,113,54,185,158
|
1903,168,1655,113,335,854,258,54,185,158,65,139,920,3085
|
-0.23791768452069523,1.8001335532224074,-0.1081959375724667,2.151887314605167,1.1386619873046315,0.4292836766633106,1.390559620323408,2.712662399939541,1.6975470899868141,1.8895785924779709,2.615058180509215,1.976437767564253,0.3823733530740993,-1.233560939945348
| 3,282
|
Monovalent inorganic cation homeostasis
| 10
| 27
| 2.420949
| 0.01548
|
O75503,Q15904,P55011,Q9Y487,P51790,P50897,P06576,Q93050,Q8N511,Q9Y6M7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
36,262,293,264,331,44,205,149,29,416
|
36,471,1331,1906,810,1117,205,2267,44,1632,331,1053,293,1825,262,29,940,988,1012,149,1032,3085,1690,264,2070,3220,416
|
2.898255890365687,0.8650522301865151,0.0862900538235537,-0.23791768452069523,0.46019487053471625,0.23757265698845073,1.6021706965552707,-0.4320142141361126,2.8635099094119285,-0.09005424964602395,1.1511243328250194,0.28653515071813196,1.2370139309648251,-0.20035758061349548,1.3790121380737033,2.9932887032618716,0.36658921531116717,0.3347961754544072,0.31878600721311506,1.9381444121492484,0.30269921647967324,-1.233560939945348,-0.1081959375724667,1.3790121380737033,-0.29502699624958933,-1.854825017955816,0.9851824752695442
| 3,282
|
Nadh dehydrogenase complex assembly
| 9
| 29
| 2.40739
| 0.016067
|
O43674,Q96CU9,Q9P0J0,P03886,O75306,O43676,O95169,Q15070,Q9H061
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
316,66,107,75,267,21,305,216,64
|
316,21,3164,2555,267,2174,740,305,2836,1656,75,721,2695,2749,216,2343,746,652,1490,862,66,2806,64,346,1244,1069,107,1780,2260
|
1.188220112815457,3.129951513482956,-1.5179982112659076,-0.6373991838940739,1.3441112138985374,-0.37265087688372656,0.5211687621279207,1.2127112505391577,-0.8778212232244633,-0.1081959375724667,2.506054203043081,0.5362387937640063,-0.7446984489999219,-0.7885304430072586,1.5478733691269635,-0.4721516811947069,0.5211687621279207,0.6105758605037124,-0.0007502583674914466,0.4292836766633106,2.599739191664418,-0.8329007565972378,2.6378827937194287,1.1135896288668288,0.15435971553016048,0.28653515071813196,2.240203443037613,-0.1631986289661192,-0.41211517468133246
| 3,282
|
Lipase activity
| 8
| 17
| 2.406254
| 0.016117
|
Q8NCG7,P38571,Q8NHP8,Q8NCC3,P09601,Q8IV08,Q9H6V9,Q8N2A8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
228,100,40,23,87,59,30,191
|
3182,87,1151,2788,2303,100,1463,59,191,368,900,23,228,40,30,1376,1415
|
-1.5994545700709446,2.3927379782175318,0.2045322897893938,-0.8329007565972378,-0.45202600377615704,2.3089861165903924,0.01683561215363658,2.682987626080082,1.6766080113317505,1.0628444846588703,0.3980834008801064,3.1108414574807464,1.5037359284595075,2.877460464329241,2.973197935039129,0.06905820401443656,0.05173904046404934
| 3,282
|
Proportionate short stature
| 9
| 33
| 2.40329
| 0.016248
|
Q14739,Q15392,Q96HY6,Q8WVQ1,P10619,Q16836,Q7RTS9,P16278,Q9Y619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
69,135,263,199,72,203,239,54,60
|
2853,948,72,690,54,928,1989,1420,2858,3227,2378,875,2938,2078,323,812,877,1824,856,676,69,135,2315,203,2755,1057,239,199,1680,263,2572,1244,60
|
-0.900491564579252,0.35073036585612155,2.537625343517015,0.5661746186246456,2.712662399939541,0.36658921531116717,-0.27588668305362396,0.03433177573533618,-0.900491564579252,-1.9438648937139937,-0.4923924005392478,0.41371997306172403,-1.0160076287643969,-0.3142725349731669,1.1759030599472666,0.46019487053471625,0.41371997306172403,-0.20035758061349548,0.4292836766633106,0.5810414981125253,2.576604864876466,2.0142460639311266,-0.45202600377615704,1.6129159816882401,-0.7885304430072586,0.28653515071813196,1.4589593479977,1.6236237566684577,-0.1081959375724667,1.3790121380737033,-0.6373991838940739,0.15435971553016048,2.682987626080082
| 3,282
|
Amino acid transmembrane transport
| 13
| 16
| 2.385794
| 0.017042
|
Q9H9B4,Q9H2J7,Q8IWT6,Q8TDW0,Q9UJS0,P30825,O75915,Q15758,P08195,Q96NB2,O60831,Q9Y619,Q15041
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
752,424,325,585,659,138,484,650,270,503,528,60,569
|
528,794,484,1601,270,138,569,650,325,585,503,424,1405,752,659,60
|
0.7684328524082645,0.47554353945259714,0.8377388499606527,-0.07200734605445942,1.3323904602126717,1.9954018657539796,0.7119066464917171,0.6105758605037124,1.1759030599472666,0.6976210318395957,0.8101935073071703,0.9720538608178498,0.05173904046404934,0.5211687621279207,0.6105758605037124,2.682987626080082
| 3,282
|
Intrinsic component of plasma membrane
| 56
| 77
| 2.384221
| 0.017115
|
P16615,O95864,Q9UJS0,O14786,P30825,Q15758,O96005,Q04721,A0FGR8,Q13641,Q99797,Q9Y289,Q9H2J7,P53985,P55011,O15118,P05067,Q15375,P07948,Q8WTV0,P04439,P05023,P41440,O60637,P35613,P51572,O43657,Q08722,P23634,Q8IWT6,Q8TDW0,P27824,P11166,P51790,P01889,P19022,Q12907,Q99805,Q9Y639,P10321,Q86UP2,O00264,Q13308,P11717,P05141,Q9BTU6,Q8N2K0,Q9UIQ6,Q9UNK0,P20020,O15498,P02786,Q9NR28,O00560,P36551,Q9H0U3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
384,508,659,892,138,650,148,912,775,284,540,945,424,544,293,417,169,558,927,49,554,810,438,58,312,313,61,568,565,325,585,950,580,331,830,834,593,84,996,587,861,224,857,478,853,369,368,111,890,618,737,240,116,371,247,771
|
775,224,371,892,417,737,61,2661,58,508,148,3167,830,240,554,810,1117,169,853,1601,927,1287,587,580,978,478,1255,384,834,618,1257,565,950,138,1545,312,247,438,313,331,544,1053,293,1795,1550,1003,912,568,593,2769,857,284,1337,2277,558,650,861,325,368,585,49,1611,1465,540,84,369,771,424,2257,116,2972,111,659,890,945,1618,996
|
0.4908216973007541,1.5148295730982289,1.0500310352209634,0.3980834008801064,0.9720538608178498,0.5211687621279207,2.6605250868804298,-0.7229807232924671,2.682987626080082,0.7963327544291974,1.9381444121492484,-1.544956106951877,0.4447751115533682,1.4476634061842635,0.7261301615080007,0.46019487053471625,0.23757265698845073,1.8001335532224074,0.4292836766633106,-0.07200734605445942,0.36658921531116717,0.12049491179844807,0.6832728352514132,0.6976210318395957,0.3347961754544072,0.8514243186018405,0.13746944516855703,1.0242489935338948,0.4447751115533682,0.6543867400016848,0.13746944516855703,0.7119066464917171,0.35073036585612155,1.9954018657539796,-0.03619440570372816,1.2004894005422622,1.4249475180109552,0.9189967934039461,1.2004894005422622,1.1511243328250194,0.740292053869216,0.28653515071813196,1.2370139309648251,-0.18172843641255768,-0.03619440570372816,0.31878600721311506,0.3823733530740993,0.7119066464917171,0.6832728352514132,-0.8106475789227858,0.4292836766633106,1.2611307098563012,0.0862900538235537,-0.4320142141361126,0.7261301615080007,0.6105758605037124,0.4292836766633106,1.1759030599472666,1.0628444846588703,0.6976210318395957,2.749321615614043,-0.07200734605445942,0.01683561215363658,0.754392795312904,2.4255716705252155,1.0628444846588703,0.5060299163255124,0.9720538608178498,-0.41211517468133246,2.1339011676066857,-1.0395551932285616,2.196377564099104,0.6105758605037124,0.41371997306172403,0.36658921531116717,-0.07200734605445942,0.3347961754544072
| 3,282
|
Sphingolipid de novo biosynthesis
| 6
| 11
| 2.380996
| 0.017266
|
O15269,P27544,O95470,Q06136,Q96G23,P51648
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
257,37,133,120,90,157
|
257,1380,2239,133,1990,37,157,120,448,90,1849
|
1.390559620323408,0.05173904046404934,-0.41211517468133246,2.0236236192967936,-0.27588668305362396,2.8913413666749483,1.8895785924779709,2.1158046507689834,0.9055948775740706,2.3844709040308296,-0.20035758061349548
| 3,282
|
Predicted secreted proteins
| 22
| 50
| 2.377575
| 0.017427
|
P80303,P43490,Q02818,Q9HB40,Q08380,Q92520,Q9BTY2,Q15165,Q9Y4P3,Q8WUJ1,P05067,Q9UMX5,O94919,P07858,Q9P2K2,O60888,O00584,Q8N128,P02786,Q9NZ08,P84157,P04083
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
2,385,9,12,271,278,151,22,415,161,169,48,180,53,456,201,212,232,240,117,249,377
|
212,892,201,603,777,180,240,377,169,1150,926,53,2240,2212,3089,2375,2837,2243,385,2334,2305,3258,840,1795,2,3239,249,9,449,271,2561,857,1337,22,636,232,3186,161,1842,278,3231,550,151,2163,2808,12,117,456,48,415
|
1.5588097511325756,0.3980834008801064,1.6129159816882401,0.6688615690298855,0.4908216973007541,1.738998392489689,1.4476634061842635,1.0371659946513645,1.8001335532224074,0.2045322897893938,0.36658921531116717,2.712662399939541,-0.41211517468133246,-0.3923277640646288,-1.2585426463884428,-0.4923924005392478,-0.8778212232244633,-0.41211517468133246,1.0242489935338948,-0.4721516811947069,-0.45202600377615704,-2.5603437852413915,0.4447751115533682,-0.18172843641255768,3.6110321470133164,-2.1283155612188787,1.4135270336371222,3.441356884702201,0.8921370887005844,1.3323904602126717,-0.6373991838940739,0.4292836766633106,0.0862900538235537,3.1235963752129488,0.6398478494370026,1.4814285535206084,-1.5994545700709446,1.8699301411864542,-0.20035758061349548,1.2969627820957583,-1.974005902654007,0.740292053869216,1.9284939850101928,-0.3530834233869732,-0.8329007565972378,3.343473503126647,2.1339011676066857,0.8921370887005844,2.7565964457504815,0.9851824752695442
| 3,282
|
Anion transport
| 46
| 74
| 2.374637
| 0.017566
|
O43681,Q9NW15,O43808,Q9UJS0,P30825,Q8TB61,Q15758,P08195,P21796,Q6NUK1,O60831,P08183,Q9Y6M7,Q9H2J7,O95563,P53985,P55011,Q9C0H2,Q9UBX3,Q9H2D1,Q9NZJ7,Q9UHG3,P45880,O43826,P41440,Q15041,Q9Y619,Q08722,Q15907,Q8IWT6,Q8TDW0,P51798,P11166,P51790,Q7L0J3,P07602,Q6KCM7,Q9H9B4,Q9HC21,O75915,Q96NB2,P28288,P12236,P30536,Q9Y277,P04083
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
639,391,758,659,138,139,650,270,15,783,528,281,416,424,795,544,293,41,167,38,301,47,50,303,438,569,60,568,447,325,585,583,580,331,332,209,730,752,772,484,503,632,378,380,252,377
|
3163,2686,3005,639,758,303,852,528,794,484,795,377,853,1601,209,281,270,580,1255,378,3089,1735,15,632,380,138,438,50,331,583,1481,544,1259,293,2962,1550,1003,568,1313,1832,569,1460,650,447,938,730,1395,783,2051,332,325,139,585,1012,503,41,38,424,1405,752,772,1567,391,301,167,47,1980,659,252,945,1378,60,3220,416
|
-1.5179982112659076,-0.7446984489999219,-1.1111173323671646,0.6252443929676549,0.5060299163255124,1.2127112505391577,0.4292836766633106,0.7684328524082645,0.47554353945259714,0.8377388499606527,0.47554353945259714,1.0371659946513645,0.4292836766633106,-0.07200734605445942,1.5805666593769274,1.2731201713397275,1.3323904602126717,0.6976210318395957,0.13746944516855703,1.0371659946513645,-1.2585426463884428,-0.144767223042154,3.223536276398023,0.6398478494370026,1.0371659946513645,1.9954018657539796,0.9189967934039461,2.7420278978751074,1.1511243328250194,0.6976210318395957,-0.0007502583674914466,0.740292053869216,0.13746944516855703,1.2370139309648251,-1.0395551932285616,-0.03619440570372816,0.31878600721311506,0.7119066464917171,0.10343536726148002,-0.20035758061349548,0.7119066464917171,0.01683561215363658,0.6105758605037124,0.9055948775740706,0.36658921531116717,0.5362387937640063,0.05173904046404934,0.4908216973007541,-0.29502699624958933,1.1511243328250194,1.1759030599472666,1.976437767564253,0.6976210318395957,0.31878600721311506,0.8101935073071703,2.877460464329241,2.8844095835048527,0.9720538608178498,0.05173904046404934,0.5211687621279207,0.5060299163255124,-0.03619440570372816,1.0242489935338948,1.2248859870045634,1.8102038397505154,2.778308473103837,-0.25685057969960273,0.6105758605037124,1.4135270336371222,0.36658921531116717,0.06905820401443656,2.682987626080082,-1.854825017955816,0.9851824752695442
| 3,282
|
Sterol biosynthetic process
| 10
| 26
| 2.370541
| 0.017762
|
Q14739,Q15392,P16435,Q15125,Q9UBM7,Q14534,Q15800,O75845,Q16850,P37268
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
69,135,265,11,176,210,89,405,183,31
|
2720,405,1783,2763,1659,833,265,31,2959,418,1954,3052,2111,2146,1313,2942,210,69,11,2860,135,1917,89,183,176,1980
|
-0.7665478813310426,0.9982576128879851,-0.18172843641255768,-0.8106475789227858,-0.1081959375724667,0.4447751115533682,1.367421765529877,2.9529597638291984,-1.0395551932285616,0.9720538608178498,-0.25685057969960273,-1.184096314811162,-0.33362432918571483,-0.3530834233869732,0.10343536726148002,-1.0160076287643969,1.5697074338437027,2.576604864876466,3.424342931133359,-0.900491564579252,2.0142460639311266,-0.23791768452069523,2.3927379782175318,1.7183433107459631,1.769720066961587,-0.25685057969960273
| 3,282
|
Protein localization to endoplasmic reticulum
| 14
| 36
| 2.36339
| 0.018109
|
O43681,Q9Y5M8,Q15005,Q9NQC3,Q96HY6,Q99442,P24390,O15258,P51572,Q15629,Q8NBM4,O43292,P46379,O43731
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
639,225,606,165,263,625,45,517,313,51,532,311,122,27
|
1047,517,311,639,27,1383,2513,1816,1152,45,2539,122,2333,313,3250,2464,2440,1292,1701,1023,2380,606,1460,51,1057,1031,532,1561,263,625,1721,165,1849,705,1411,225
|
0.28653515071813196,0.7824126866297165,1.2004894005422622,0.6252443929676549,2.9999531979248477,0.05173904046404934,-0.5953632204872029,-0.20035758061349548,0.2045322897893938,2.821234068592441,-0.6163193962217591,2.0975965576515088,-0.4721516811947069,1.2004894005422622,-2.321881693407483,-0.553816606593548,-0.5332236662674483,0.12049491179844807,-0.12643329600044367,0.30269921647967324,-0.4923924005392478,0.6688615690298855,0.01683561215363658,2.7273834505609806,0.28653515071813196,0.30269921647967324,0.7684328524082645,-0.03619440570372816,1.3790121380737033,0.6543867400016848,-0.12643329600044367,1.8202406866208516,-0.20035758061349548,0.5661746186246456,0.05173904046404934,1.5148295730982289
| 3,282
|
Carbohydrate derivative catabolic process
| 15
| 35
| 2.362418
| 0.018156
|
O60502,P15586,P04066,P36639,Q13126,Q9H773,P07686,P04062,Q9NUJ1,P06865,P16278,Q9BTY2,P17900,P06280,P54802
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,258,322,234,76,110,335,145,310,113,54,151,246,184,185
|
2530,129,2691,2855,145,322,184,113,335,854,2693,258,54,246,3232,3246,620,234,1630,2037,909,185,1957,76,638,3271,1681,151,525,3166,110,310,2095,350,2235
|
-0.6163193962217591,2.060840721286124,-0.7446984489999219,-0.900491564579252,1.9573524101711695,1.1759030599472666,1.6975470899868141,2.151887314605167,1.1386619873046315,0.4292836766633106,-0.7446984489999219,1.390559620323408,2.712662399939541,1.4249475180109552,-2.0043827630423245,-2.2562977075631707,0.6543867400016848,1.4702143094966997,-0.09005424964602395,-0.29502699624958933,0.3823733530740993,1.6975470899868141,-0.25685057969960273,2.506054203043081,0.6398478494370026,-3.6383602587210095,-0.1081959375724667,1.9284939850101928,0.7824126866297165,-1.5179982112659076,2.196377564099104,1.2127112505391577,-0.3142725349731669,1.1135896288668288,-0.3923277640646288
| 3,282
|
Glycosyl compound catabolic process
| 6
| 9
| 2.36004
| 0.018273
|
P36639,Q13126,P04062,Q9NUJ1,Q9BTY2,P06280
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
234,76,145,310,151,184
|
2691,145,322,184,854,234,76,151,310
|
-0.7446984489999219,1.9573524101711695,1.1759030599472666,1.6975470899868141,0.4292836766633106,1.4702143094966997,2.506054203043081,1.9284939850101928,1.2127112505391577
| 3,282
|
Microcornea
| 6
| 30
| 2.323752
| 0.020139
|
Q8NCH0,Q9NWM8,O43505,Q15125,P36404,Q13045
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,355,168,11,18,314
|
2137,168,2173,2101,405,2176,617,1118,2694,1543,2378,18,1821,2036,812,1580,314,1915,1460,11,1056,1771,2319,2881,65,1721,1497,355,973,806
|
-0.3530834233869732,1.8001335532224074,-0.37265087688372656,-0.33362432918571483,0.9982576128879851,-0.37265087688372656,0.6543867400016848,0.23757265698845073,-0.7446984489999219,-0.03619440570372816,-0.4923924005392478,3.186489069229093,-0.20035758061349548,-0.29502699624958933,0.46019487053471625,-0.05405435237037845,1.2004894005422622,-0.23791768452069523,0.01683561215363658,3.424342931133359,0.28653515071813196,-0.1631986289661192,-0.45202600377615704,-0.9233040534854985,2.615058180509215,-0.12643329600044367,-0.0007502583674914466,1.1009789242465366,0.35073036585612155,0.47554353945259714
| 3,282
|
transmembrane signal receptor
| 6
| 8
| 2.322427
| 0.02021
|
O00264,Q8WUJ1,Q9UMX5,O15173,Q99720,O75787
|
Functions
|
Panther Protein class
|
panther_protein_class
|
224,161,48,114,26,471
|
224,114,471,558,161,26,1110,48
|
1.5148295730982289,2.1429079626659977,0.8650522301865151,0.7261301615080007,1.8699301411864542,3.006601594300328,0.25397254379079565,2.7565964457504815
| 3,282
|
Abnormal femoral neck head morphology
| 13
| 43
| 2.320828
| 0.020296
|
Q14739,P55011,Q96HY6,Q9Y487,Q8WVQ1,Q96A33,O95831,Q7RTS9,O75844,P16278,Q96AY3,Q9Y619,Q7LGA3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
69,293,263,264,199,299,237,239,80,54,214,60,158
|
1181,2853,1571,603,80,237,977,322,54,3133,1420,2267,1543,2938,811,3040,1791,694,1425,293,1701,69,2637,1026,2799,1394,1366,158,239,2281,199,299,214,263,2573,514,1439,3189,973,2486,264,2581,60
|
0.18789041292229028,-0.900491564579252,-0.05405435237037845,0.6688615690298855,2.4499538883891847,1.4589593479977,0.3347961754544072,1.1759030599472666,2.712662399939541,-1.3860262152164,0.03433177573533618,-0.4320142141361126,-0.03619440570372816,-1.0160076287643969,0.46019487053471625,-1.159609495028328,-0.18172843641255768,0.5661746186246456,0.03433177573533618,1.2370139309648251,-0.12643329600044367,2.576604864876466,-0.7013933032185452,0.30269921647967324,-0.8329007565972378,0.05173904046404934,0.06905820401443656,1.8895785924779709,1.4589593479977,-0.4320142141361126,1.6236237566684577,1.2248859870045634,1.5588097511325756,1.3790121380737033,-0.6373991838940739,0.7963327544291974,0.03433177573533618,-1.6270001302540178,0.35073036585612155,-0.553816606593548,1.3790121380737033,-0.6373991838940739,2.682987626080082
| 3,282
|
Retrograde transport endosome to golgi
| 11
| 29
| 2.319305
| 0.020378
|
O60749,O75503,Q96QK1,Q13190,O95249,Q4J6C6,O60499,P53367,O15498,Q8NBN3,Q14203
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
507,36,788,521,144,338,179,461,737,118,696
|
1476,737,1115,1937,179,507,997,36,144,1820,1632,461,1604,521,1482,696,338,983,118,1561,1881,788,1084,1749,2020,2682,825,1089,2070
|
-0.0007502583674914466,0.5211687621279207,0.23757265698845073,-0.25685057969960273,1.738998392489689,0.7963327544291974,0.31878600721311506,2.898255890365687,1.9573524101711695,-0.20035758061349548,-0.09005424964602395,0.8786230124808344,-0.07200734605445942,0.7824126866297165,-0.0007502583674914466,0.5661746186246456,1.1261505340235223,0.3347961754544072,2.124866780378862,-0.03619440570372816,-0.21908700961772024,0.4908216973007541,0.2702931493830407,-0.144767223042154,-0.27588668305362396,-0.7229807232924671,0.46019487053471625,0.2702931493830407,-0.29502699624958933
| 3,282
|
Aplasia hypoplasia involving bones of the thorax
| 11
| 37
| 2.318943
| 0.020398
|
Q9UHX1,P48651,Q14739,Q8TAA9,Q96HY6,P16435,P98175,Q7RTS9,O75844,Q9BV10,Q9Y619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
229,323,69,101,263,265,172,239,80,248,60
|
1857,403,2853,948,1571,80,2813,977,265,778,3133,2745,1387,1821,323,1996,172,742,3135,546,69,1026,713,1917,2799,1771,1366,239,1234,964,1712,101,263,989,248,229,60
|
-0.21908700961772024,0.9982576128879851,-0.900491564579252,0.35073036585612155,-0.05405435237037845,2.4499538883891847,-0.8552914666396761,0.3347961754544072,1.367421765529877,0.4908216973007541,-1.3860262152164,-0.7885304430072586,0.05173904046404934,-0.20035758061349548,1.1759030599472666,-0.27588668305362396,1.7798918673967443,0.5211687621279207,-1.3860262152164,0.740292053869216,2.576604864876466,0.30269921647967324,0.5512405638431472,-0.23791768452069523,-0.8329007565972378,-0.1631986289661192,0.06905820401443656,1.4589593479977,0.15435971553016048,0.35073036585612155,-0.12643329600044367,2.3089861165903924,1.3790121380737033,0.3347961754544072,1.4249475180109552,1.5037359284595075,2.682987626080082
| 3,282
|
Cis golgi network
| 8
| 16
| 2.31782
| 0.020459
|
P49755,P24390,O95249,P30533,Q8TBA6,O00461,P98194,O43731
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
386,45,144,365,339,85,407,27
|
85,27,144,45,365,386,407,640,882,451,339,1272,1561,2355,1613,807
|
2.4173982018988323,2.9999531979248477,1.9573524101711695,2.821234068592441,1.0628444846588703,1.0242489935338948,0.9982576128879851,0.6252443929676549,0.41371997306172403,0.8921370887005844,1.1261505340235223,0.13746944516855703,-0.03619440570372816,-0.4721516811947069,-0.07200734605445942,0.47554353945259714
| 3,282
|
Golgi cisterna membrane
| 14
| 19
| 2.317436
| 0.02048
|
Q10713,Q10472,Q08379,Q8WVQ1,Q8NBZ7,Q9Y6B6,Q08378,P98194,O00461,Q12893,Q99523,Q8NBN3,P51572,Q9H4A6
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
227,390,640,199,452,601,743,407,85,530,342,118,313,516
|
85,313,407,743,640,782,390,227,530,899,118,452,1272,199,2355,342,516,1327,601
|
2.4173982018988323,1.2004894005422622,0.9982576128879851,0.5211687621279207,0.6252443929676549,0.4908216973007541,1.0242489935338948,1.5037359284595075,0.7684328524082645,0.3980834008801064,2.124866780378862,0.8921370887005844,0.13746944516855703,1.6236237566684577,-0.4721516811947069,1.1261505340235223,0.7963327544291974,0.10343536726148002,0.6832728352514132
| 3,282
|
Calcium transport
| 7
| 8
| 2.31586
| 0.020566
|
P23634,P16615,Q9BPX6,Q8NE86,O95202,P98194,Q9UM00
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
565,384,354,488,394,407,541
|
394,384,618,565,407,488,354,541
|
1.0112796586421209,1.0242489935338948,0.6543867400016848,0.7119066464917171,0.9982576128879851,0.8377388499606527,1.1009789242465366,0.754392795312904
| 3,282
|
FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]
| 7
| 11
| 2.3115
| 0.020805
|
Q9NWM8,Q9Y680,P26885,Q00688,P62942,Q02790,Q96AY3
|
Sequence
|
InterPro Domain
|
interpro_domain
|
355,99,543,519,79,244,214
|
1179,543,79,519,244,605,1523,1295,214,355,99
|
0.18789041292229028,0.740292053869216,2.4660946890466375,0.7824126866297165,1.4363262187738342,0.6688615690298855,-0.018426654504152068,0.12049491179844807,1.5588097511325756,1.1009789242465366,2.325930995779964
| 3,282
|
Organophosphate ester transport
| 18
| 26
| 2.304563
| 0.021191
|
O43808,Q14108,Q08722,Q8IWT6,Q9H2D1,Q8TDW0,P05141,Q8TB61,P61916,Q6NUK1,Q8WTV0,Q6KCM7,O43826,P41440,P08183,Q9HC21,P12236,Q4KMQ2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
758,3,568,325,38,585,853,139,840,783,49,730,303,438,281,772,378,938
|
758,303,3167,853,281,1255,378,1990,2514,438,1333,840,568,3,938,730,783,325,139,585,49,969,38,772,1688,1849
|
0.5060299163255124,1.2127112505391577,-1.544956106951877,0.4292836766633106,1.2731201713397275,0.13746944516855703,1.0371659946513645,-0.27588668305362396,-0.5953632204872029,0.9189967934039461,0.0862900538235537,0.4447751115533682,0.7119066464917171,3.4972936020541496,0.36658921531116717,0.5362387937640063,0.4908216973007541,1.1759030599472666,1.976437767564253,0.6976210318395957,2.749321615614043,0.35073036585612155,2.8844095835048527,0.5060299163255124,-0.1081959375724667,-0.20035758061349548
| 3,282
|
Cellular monovalent inorganic cation homeostasis
| 10
| 25
| 2.29772
| 0.021578
|
O75503,Q15904,P55011,Q9Y487,P51790,P50897,P06576,Q93050,Q8N511,Q9Y6M7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
36,262,293,264,331,44,205,149,29,416
|
36,471,1331,810,1117,205,2267,44,1632,331,1053,293,1825,262,29,940,988,1012,149,1032,3085,1690,264,3220,416
|
2.898255890365687,0.8650522301865151,0.0862900538235537,0.46019487053471625,0.23757265698845073,1.6021706965552707,-0.4320142141361126,2.8635099094119285,-0.09005424964602395,1.1511243328250194,0.28653515071813196,1.2370139309648251,-0.20035758061349548,1.3790121380737033,2.9932887032618716,0.36658921531116717,0.3347961754544072,0.31878600721311506,1.9381444121492484,0.30269921647967324,-1.233560939945348,-0.1081959375724667,1.3790121380737033,-1.854825017955816,0.9851824752695442
| 3,282
|
Macrolide binding
| 6
| 7
| 2.297546
| 0.021588
|
Q9Y680,P26885,Q00688,P62942,Q02790,Q96AY3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
99,543,519,79,244,214
|
543,79,519,244,605,214,99
|
0.740292053869216,2.4660946890466375,0.7824126866297165,1.4363262187738342,0.6688615690298855,1.5588097511325756,2.325930995779964
| 3,282
|
Fk506 binding
| 6
| 7
| 2.297546
| 0.021588
|
Q9Y680,P26885,Q00688,P62942,Q02790,Q96AY3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
99,543,519,79,244,214
|
543,79,519,244,605,214,99
|
0.740292053869216,2.4660946890466375,0.7824126866297165,1.4363262187738342,0.6688615690298855,1.5588097511325756,2.325930995779964
| 3,282
|
Hand polydactyly
| 15
| 33
| 2.296521
| 0.021646
|
Q13045,Q10713,Q9UHX1,Q15067,Q14739,P21964,O95202,Q15125,P98175,Q9UBM7,O96028,O75845,O60826,Q9Y263,Q9UM00
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
314,227,229,419,69,379,394,11,172,176,376,405,403,91,541
|
1982,403,405,394,376,3133,379,3146,2669,1700,172,227,546,314,3203,69,2148,419,11,1234,2881,1712,2521,2420,3229,1108,2199,1242,176,229,973,541,91
|
-0.27588668305362396,0.9982576128879851,0.9982576128879851,1.0112796586421209,1.0371659946513645,-1.3860262152164,1.0371659946513645,-1.4382608481916126,-0.7229807232924671,-0.12643329600044367,1.7798918673967443,1.5037359284595075,0.740292053869216,1.2004894005422622,-1.7108530645839468,2.576604864876466,-0.3530834233869732,0.9720538608178498,3.424342931133359,0.15435971553016048,-0.9233040534854985,-0.12643329600044367,-0.5953632204872029,-0.5127493328269307,-1.9438648937139937,0.25397254379079565,-0.37265087688372656,0.15435971553016048,1.769720066961587,1.5037359284595075,0.35073036585612155,0.754392795312904,2.3844709040308296
| 3,282
|
Horizontal nystagmus
| 7
| 24
| 2.291989
| 0.021906
|
O60313,Q9NZJ7,O95831,P04062,P07602,O14773,Q9H061
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
193,301,237,145,209,81,64
|
1653,808,81,193,1783,237,145,209,581,1480,694,1120,1824,2336,2415,1670,1344,1645,64,1533,391,2623,301,2326
|
-0.1081959375724667,0.46019487053471625,2.4255716705252155,1.6555243256802743,-0.18172843641255768,1.4589593479977,1.9573524101711695,1.5805666593769274,0.6976210318395957,-0.0007502583674914466,0.5661746186246456,0.23757265698845073,-0.20035758061349548,-0.4721516811947069,-0.5127493328269307,-0.1081959375724667,0.0862900538235537,-0.09005424964602395,2.6378827937194287,-0.018426654504152068,1.0242489935338948,-0.6799348090885988,1.2248859870045634,-0.45202600377615704
| 3,282
|
Glycoprotein biosynthetic process
| 33
| 54
| 2.291198
| 0.021952
|
O60502,Q10472,Q08379,Q9NY97,Q9NY61,Q10471,Q13724,Q7LGA3,O15118,O43505,Q6ZXV5,Q8NCH0,Q86YN1,Q16706,Q8WVQ1,O60762,Q99805,Q9UKM7,Q9BXS4,Q8N4A0,Q2TAA5,P04843,P61803,P04844,P35222,P46977,P35610,Q8TCJ2,Q9BV10,Q9H0U3,Q9H4A6,Q9BT22,Q9NYU2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,390,640,920,792,782,155,158,417,168,572,65,195,451,199,578,84,350,221,94,858,485,741,873,875,373,620,638,248,771,516,515,642
|
1810,417,2430,3058,168,129,2533,578,1284,1812,2208,485,873,875,620,1075,373,741,1139,1580,1997,640,782,390,155,1006,451,858,1834,1586,572,158,2153,195,94,65,638,199,1611,2355,84,515,248,221,771,2478,516,792,920,642,3085,350,946,1114
|
-0.20035758061349548,0.9720538608178498,-0.5332236662674483,-1.2087461517878753,1.8001335532224074,2.060840721286124,-0.6163193962217591,0.6976210318395957,0.12049491179844807,-0.20035758061349548,-0.3923277640646288,0.8377388499606527,0.41371997306172403,0.41371997306172403,0.6543867400016848,0.2702931493830407,1.0500310352209634,0.5211687621279207,0.22109280361990064,-0.05405435237037845,-0.27588668305362396,0.6252443929676549,0.4908216973007541,1.0242489935338948,1.9090993860580008,0.31878600721311506,0.8921370887005844,0.4292836766633106,-0.20035758061349548,-0.05405435237037845,0.7119066464917171,1.8895785924779709,-0.3530834233869732,1.634294253015559,2.351164407618706,2.615058180509215,0.6398478494370026,1.6236237566684577,-0.07200734605445942,-0.4721516811947069,2.4255716705252155,0.7963327544291974,1.4249475180109552,1.5368980435154267,0.5060299163255124,-0.553816606593548,0.7963327544291974,0.4908216973007541,0.3823733530740993,0.6252443929676549,-1.233560939945348,1.1135896288668288,0.36658921531116717,0.25397254379079565
| 3,282
|
Respirasome
| 14
| 44
| 2.28037
| 0.022586
|
Q96CU9,O14949,Q9UDW1,P00403,Q9P0J0,P03886,O75306,Q13423,P14406,Q6DKK2,O43676,O95169,Q9Y241,P13073
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
66,35,68,292,107,75,267,238,16,146,21,305,56,153
|
1725,793,35,316,21,3164,2555,267,2174,740,305,3217,2836,1656,292,75,721,1254,2211,153,16,2919,3120,663,1989,837,2695,3227,2920,1866,3202,2749,238,2343,746,146,1490,66,1244,107,68,56,1780,2260
|
-0.144767223042154,0.47554353945259714,2.9120334629969933,1.188220112815457,3.129951513482956,-1.5179982112659076,-0.6373991838940739,1.3441112138985374,-0.37265087688372656,0.5211687621279207,1.2127112505391577,-1.8255957659988549,-0.8778212232244633,-0.1081959375724667,1.2370139309648251,2.506054203043081,0.5362387937640063,0.13746944516855703,-0.3923277640646288,1.918812369361769,3.198894574749169,-0.9926104125098789,-1.360179198444861,0.5958417361485769,-0.27588668305362396,0.4447751115533682,-0.7446984489999219,-1.9438648937139937,-0.9926104125098789,-0.21908700961772024,-1.7108530645839468,-0.7885304430072586,1.4589593479977,-0.4721516811947069,0.5211687621279207,1.9573524101711695,-0.0007502583674914466,2.599739191664418,0.15435971553016048,2.240203443037613,2.592048628230388,2.6904356298930083,-0.1631986289661192,-0.41211517468133246
| 3,282
|
Hormone metabolic process
| 11
| 31
| 2.255147
| 0.024124
|
O95470,P42892,P16435,Q53GQ0,Q9HB40,P30536,Q9UBM7,O75844,P07858,Q14849,O75787
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
133,71,265,204,12,380,176,80,53,250,471
|
2074,471,80,1655,133,810,53,2375,3132,265,380,71,3076,1258,3135,250,1770,204,487,636,678,1062,1713,3228,2289,3105,12,867,176,2326,1473
|
-0.3142725349731669,0.8650522301865151,2.4499538883891847,-0.1081959375724667,2.0236236192967936,0.46019487053471625,2.712662399939541,-0.4923924005392478,-1.3860262152164,1.367421765529877,1.0371659946513645,2.5532811124501102,-1.233560939945348,0.13746944516855703,-1.3860262152164,1.4135270336371222,-0.1631986289661192,1.6129159816882401,0.8377388499606527,0.6398478494370026,0.5810414981125253,0.28653515071813196,-0.12643329600044367,-1.9438648937139937,-0.4320142141361126,-1.2836932720831662,3.343473503126647,0.4292836766633106,1.769720066961587,-0.45202600377615704,0.01683561215363658
| 3,282
|
Cholesterol metabolism with bloch and kandutschrussell pathways
| 10
| 25
| 2.254331
| 0.024175
|
Q14739,P48449,Q15392,Q15125,Q9UBM7,Q14534,Q15800,O75845,Q16850,P37268
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
69,418,135,11,176,210,89,405,183,31
|
688,1695,405,1507,508,833,1863,620,31,418,1950,3052,2111,2146,2942,210,69,11,2860,135,1917,89,183,2252,176
|
0.5661746186246456,-0.12643329600044367,0.9982576128879851,-0.018426654504152068,0.7963327544291974,0.4447751115533682,-0.21908700961772024,0.6543867400016848,2.9529597638291984,0.9720538608178498,-0.25685057969960273,-1.184096314811162,-0.33362432918571483,-0.3530834233869732,-1.0160076287643969,1.5697074338437027,2.576604864876466,3.424342931133359,-0.900491564579252,2.0142460639311266,-0.23791768452069523,2.3927379782175318,1.7183433107459631,-0.41211517468133246,1.769720066961587
| 3,282
|
Aminoglycan metabolic process
| 8
| 15
| 2.251786
| 0.024336
|
Q8NCH0,P15586,P04066,O43505,P06865,P16278,P54802,Q7LGA3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,258,322,168,113,54,185,158
|
168,2533,1728,322,113,335,854,258,54,185,1604,3187,158,65,920
|
1.8001335532224074,-0.6163193962217591,-0.144767223042154,1.1759030599472666,2.151887314605167,1.1386619873046315,0.4292836766633106,1.390559620323408,2.712662399939541,1.6975470899868141,-0.07200734605445942,-1.6270001302540178,1.8895785924779709,2.615058180509215,0.3823733530740993
| 3,282
|
Sterol metabolism
| 7
| 29
| 2.251276
| 0.024368
|
Q14739,Q15392,Q15125,Q9UBM7,P04062,Q15800,P37268
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
69,135,11,176,145,89,31
|
417,2720,405,1783,2763,3167,145,833,2956,620,31,3052,840,1913,2111,2146,1313,2942,69,11,2860,135,1917,89,183,1124,176,1112,1980
|
0.9720538608178498,-0.7665478813310426,0.9982576128879851,-0.18172843641255768,-0.8106475789227858,-1.544956106951877,1.9573524101711695,0.4447751115533682,-1.0395551932285616,0.6543867400016848,2.9529597638291984,-1.184096314811162,0.4447751115533682,-0.23791768452069523,-0.33362432918571483,-0.3530834233869732,0.10343536726148002,-1.0160076287643969,2.576604864876466,3.424342931133359,-0.900491564579252,2.0142460639311266,-0.23791768452069523,2.3927379782175318,1.7183433107459631,0.23757265698845073,1.769720066961587,0.25397254379079565,-0.25685057969960273
| 3,282
|
Abnormal femoral neck morphology
| 11
| 37
| 2.241824
| 0.024973
|
P55011,Q96HY6,Q9Y487,Q8WVQ1,Q96A33,O95831,Q7RTS9,O75844,P16278,Q96AY3,Q9Y619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
293,263,264,199,299,237,239,80,54,214,60
|
1181,2853,1571,603,80,237,977,322,54,3133,1420,2267,1543,811,3040,1791,694,1425,293,1701,2637,1026,2799,1394,239,199,299,214,263,2573,514,3189,973,2486,264,2581,60
|
0.18789041292229028,-0.900491564579252,-0.05405435237037845,0.6688615690298855,2.4499538883891847,1.4589593479977,0.3347961754544072,1.1759030599472666,2.712662399939541,-1.3860262152164,0.03433177573533618,-0.4320142141361126,-0.03619440570372816,0.46019487053471625,-1.159609495028328,-0.18172843641255768,0.5661746186246456,0.03433177573533618,1.2370139309648251,-0.12643329600044367,-0.7013933032185452,0.30269921647967324,-0.8329007565972378,0.05173904046404934,1.4589593479977,1.6236237566684577,1.2248859870045634,1.5588097511325756,1.3790121380737033,-0.6373991838940739,0.7963327544291974,-1.6270001302540178,0.35073036585612155,-0.553816606593548,1.3790121380737033,-0.6373991838940739,2.682987626080082
| 3,282
|
Basolateral plasma membrane
| 26
| 45
| 2.236516
| 0.025318
|
P30825,P08195,Q12846,Q9Y6M7,Q9Y289,P53985,P55011,Q14254,P41440,P05023,P35613,P26038,P23634,O75955,Q07157,P11166,P08238,P19022,Q14168,P15311,P57105,Q6P4Q7,P20020,P02786,P35222,P04083
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
138,270,913,416,945,544,293,677,438,810,312,692,565,689,709,580,832,834,726,588,226,242,618,240,875,377
|
2262,1208,689,1540,3167,240,377,810,1117,926,270,832,580,1817,2375,588,1818,834,618,565,692,138,2268,875,312,438,544,1053,293,226,1155,1795,709,913,2411,1666,726,677,242,1465,1374,1532,1346,945,416
|
-0.4320142141361126,0.17116646162302224,0.5661746186246456,-0.03619440570372816,-1.544956106951877,1.4476634061842635,1.0371659946513645,0.46019487053471625,0.23757265698845073,0.36658921531116717,1.3323904602126717,0.4447751115533682,0.6976210318395957,-0.20035758061349548,-0.4923924005392478,0.6832728352514132,-0.20035758061349548,0.4447751115533682,0.6543867400016848,0.7119066464917171,0.5661746186246456,1.9954018657539796,-0.4320142141361126,0.41371997306172403,1.2004894005422622,0.9189967934039461,0.740292053869216,0.28653515071813196,1.2370139309648251,1.5037359284595075,0.2045322897893938,-0.18172843641255768,0.5512405638431472,0.3823733530740993,-0.5127493328269307,-0.1081959375724667,0.5362387937640063,0.5810414981125253,1.4476634061842635,0.01683561215363658,0.06905820401443656,-0.018426654504152068,0.0862900538235537,0.36658921531116717,0.9851824752695442
| 3,282
|
Vertebral segmentation defect
| 12
| 31
| 2.216944
| 0.026627
|
P61978,Q9UHX1,Q8TAA9,P16435,O95202,Q15125,Q9Y2W2,O96028,O60826,Q9Y619,Q9UM00,Q9Y4P3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
480,229,101,265,394,11,302,376,403,60,541,415
|
1282,2173,403,2853,394,376,265,928,778,3133,2034,811,480,3069,1739,546,3203,883,11,1010,963,101,1847,229,1897,541,302,415,2581,60,1474
|
0.12049491179844807,-0.37265087688372656,0.9982576128879851,-0.900491564579252,1.0112796586421209,1.0371659946513645,1.367421765529877,0.36658921531116717,0.4908216973007541,-1.3860262152164,-0.29502699624958933,0.46019487053471625,0.8514243186018405,-1.2087461517878753,-0.144767223042154,0.740292053869216,-1.7108530645839468,0.41371997306172403,3.424342931133359,0.31878600721311506,0.35073036585612155,2.3089861165903924,-0.20035758061349548,1.5037359284595075,-0.21908700961772024,0.754392795312904,1.2248859870045634,0.9851824752695442,-0.6373991838940739,2.682987626080082,0.01683561215363658
| 3,282
|
Bulbar signs
| 6
| 13
| 2.215988
| 0.026692
|
P35637,P03886,P04062,P07602,Q99720,Q9Y263
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
297,75,145,209,26,91
|
639,75,721,145,1907,209,1731,297,931,534,26,301,91
|
0.6252443929676549,2.506054203043081,0.5362387937640063,1.9573524101711695,-0.23791768452069523,1.5805666593769274,-0.144767223042154,1.2248859870045634,0.36658921531116717,0.7684328524082645,3.006601594300328,1.2248859870045634,2.3844709040308296
| 3,282
|
Decreased activity of mitochondrial complex i
| 8
| 33
| 2.214646
| 0.026784
|
Q9NPL8,Q96CU9,Q9UBX3,P03886,O75306,Q70HW3,O43676,Q9Y584
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
326,66,167,75,267,13,21,57
|
21,2555,267,2174,1187,1656,75,3120,2695,3066,3202,2749,1120,2839,1266,2279,13,1490,862,1320,66,1680,1435,2806,2681,346,326,1244,1069,167,2889,57,2260
|
3.129951513482956,-0.6373991838940739,1.3441112138985374,-0.37265087688372656,0.18789041292229028,-0.1081959375724667,2.506054203043081,-1.360179198444861,-0.7446984489999219,-1.2087461517878753,-1.7108530645839468,-0.7885304430072586,0.23757265698845073,-0.8778212232244633,0.13746944516855703,-0.4320142141361126,3.319910808935396,-0.0007502583674914466,0.4292836766633106,0.10343536726148002,2.599739191664418,-0.1081959375724667,0.03433177573533618,-0.8329007565972378,-0.7229807232924671,1.1135896288668288,1.1759030599472666,0.15435971553016048,0.28653515071813196,1.8102038397505154,-0.9233040534854985,2.6904356298930083,-0.41211517468133246
| 3,282
|
Inner mitochondrial membrane organization
| 12
| 23
| 2.209372
| 0.027149
|
Q5XKP0,Q9Y512,O60313,Q5HYI7,O95202,Q9P0J0,Q6UXV4,Q9H3K2,Q13505,Q9NX63,Q16891,Q9Y584
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
570,458,193,97,394,107,651,402,25,348,412,57
|
924,193,1571,2075,394,2938,25,412,2222,97,570,651,1145,2163,402,805,348,107,687,458,57,905,2025
|
0.36658921531116717,1.6555243256802743,-0.05405435237037845,-0.3142725349731669,1.0112796586421209,-1.0160076287643969,3.0526953443372964,0.9851824752695442,-0.3923277640646288,2.325930995779964,0.7119066464917171,0.6105758605037124,0.22109280361990064,-0.3530834233869732,1.0112796586421209,0.47554353945259714,1.1135896288668288,2.240203443037613,0.5810414981125253,0.8921370887005844,2.6904356298930083,0.3980834008801064,-0.27588668305362396
| 3,282
|
Steroid metabolism
| 7
| 30
| 2.207509
| 0.027279
|
Q14739,Q15392,Q15125,Q9UBM7,P04062,Q15800,P37268
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
69,135,11,176,145,89,31
|
417,2720,405,1783,2763,3167,145,833,2956,620,31,3052,840,1913,2111,2146,1313,2942,69,11,2860,135,1917,89,183,1124,3105,176,1112,1980
|
0.9720538608178498,-0.7665478813310426,0.9982576128879851,-0.18172843641255768,-0.8106475789227858,-1.544956106951877,1.9573524101711695,0.4447751115533682,-1.0395551932285616,0.6543867400016848,2.9529597638291984,-1.184096314811162,0.4447751115533682,-0.23791768452069523,-0.33362432918571483,-0.3530834233869732,0.10343536726148002,-1.0160076287643969,2.576604864876466,3.424342931133359,-0.900491564579252,2.0142460639311266,-0.23791768452069523,2.3927379782175318,1.7183433107459631,0.23757265698845073,-1.2836932720831662,1.769720066961587,0.25397254379079565,-0.25685057969960273
| 3,282
|
Metal ion transmembrane transporter activity
| 18
| 25
| 2.205767
| 0.0274
|
Q9Y289,P16615,Q9H2J7,P23634,Q8N4V1,Q8NE86,P55011,O95202,P08195,Q6P4Q7,P20020,Q93034,P98194,P05023,Q9H0U3,Q9HD20,Q9UM00,Q9Y6M7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
945,384,424,565,223,488,293,394,270,242,618,732,407,810,771,188,541,416
|
394,810,1117,926,2105,270,384,618,565,293,2380,407,2877,242,223,488,1012,732,1589,771,424,188,541,945,416
|
1.0112796586421209,0.46019487053471625,0.23757265698845073,0.36658921531116717,-0.33362432918571483,1.3323904602126717,1.0242489935338948,0.6543867400016848,0.7119066464917171,1.2370139309648251,-0.4923924005392478,0.9982576128879851,-0.9233040534854985,1.4476634061842635,1.5258835277656888,0.8377388499606527,0.31878600721311506,0.5362387937640063,-0.05405435237037845,0.5060299163255124,0.9720538608178498,1.6870955164987091,0.754392795312904,0.36658921531116717,0.9851824752695442
| 3,282
|
Protein localization to mitochondrion
| 21
| 64
| 2.205717
| 0.027404
|
Q9NS69,Q99595,Q8N4H5,Q9NX47,O60830,O14737,O43615,Q9Y584,P51572,Q9Y512,Q9Y6C9,Q15388,P55786,Q15070,Q9H300,Q10713,Q9P0J0,O95831,P30536,Q9GZY8,O14925
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,4,5,392,10,143,282,57,313,458,470,202,82,216,345,227,107,237,380,381,253
|
1179,1653,808,143,253,282,924,10,2719,2075,1418,2690,1285,237,1000,831,1287,2891,472,2892,1946,1544,380,1947,2790,2037,313,724,82,2040,227,1313,216,202,2278,960,2222,635,1878,5,1747,679,1145,1678,2574,4,540,3073,381,345,2868,0,392,107,2134,2166,1780,629,2168,458,57,905,2025,470
|
0.18789041292229028,-0.1081959375724667,0.46019487053471625,1.9573524101711695,1.402064492860211,1.2611307098563012,0.36658921531116717,3.4356976780399577,-0.7665478813310426,-0.3142725349731669,0.03433177573533618,-0.7446984489999219,0.12049491179844807,1.4589593479977,0.31878600721311506,0.4447751115533682,0.12049491179844807,-0.9462602777918803,0.8650522301865151,-0.9462602777918803,-0.25685057969960273,-0.03619440570372816,1.0371659946513645,-0.25685057969960273,-0.8329007565972378,-0.29502699624958933,1.2004894005422622,0.5362387937640063,2.4255716705252155,-0.29502699624958933,1.5037359284595075,0.10343536726148002,1.5478733691269635,1.6129159816882401,-0.4320142141361126,0.35073036585612155,-0.3923277640646288,0.6398478494370026,-0.21908700961772024,3.4806364511034387,-0.144767223042154,0.5810414981125253,0.22109280361990064,-0.1081959375724667,-0.6373991838940739,3.491752883087718,0.754392795312904,-1.2087461517878753,1.0371659946513645,1.1135896288668288,-0.900491564579252,4.030799979701142,1.0242489935338948,2.240203443037613,-0.33362432918571483,-0.3530834233869732,-0.1631986289661192,0.6543867400016848,-0.3530834233869732,0.8921370887005844,2.6904356298930083,0.3980834008801064,-0.27588668305362396,0.8786230124808344
| 3,282
|
Impaired proprioception
| 13
| 38
| 2.197406
| 0.027991
|
Q8N0X7,Q12768,O75298,P20700,Q6UWE0,Q9Y6B6,O14773,P41440,Q13217,P54802,Q8IV08,Q9Y619,Q9H6K4
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
511,546,197,581,442,601,81,438,462,185,59,60,93
|
81,1782,1019,197,1783,1418,1150,2891,1733,2892,581,1421,2610,438,2306,185,1824,2895,2752,1580,546,462,595,2473,442,59,511,1344,1924,1886,1240,93,2292,2654,2326,60,601,1446
|
2.4255716705252155,-0.18172843641255768,0.30269921647967324,1.6236237566684577,-0.18172843641255768,0.03433177573533618,0.2045322897893938,-0.9462602777918803,-0.144767223042154,-0.9462602777918803,0.6976210318395957,0.03433177573533618,-0.6799348090885988,0.9189967934039461,-0.45202600377615704,1.6975470899868141,-0.20035758061349548,-0.9462602777918803,-0.7885304430072586,-0.05405435237037845,0.740292053869216,0.8786230124808344,0.6832728352514132,-0.553816606593548,0.9189967934039461,2.682987626080082,0.7963327544291974,0.0862900538235537,-0.23791768452069523,-0.21908700961772024,0.15435971553016048,2.3595270048660506,-0.4320142141361126,-0.7013933032185452,-0.45202600377615704,2.682987626080082,0.6832728352514132,0.03433177573533618
| 3,282
|
Cholesterol metabolism
| 7
| 27
| 2.181043
| 0.02918
|
Q14739,Q15392,Q15125,Q9UBM7,P04062,Q15800,P37268
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
69,135,11,176,145,89,31
|
417,2720,1783,2763,3167,145,833,2956,620,31,3052,840,1913,2111,2146,1313,2942,69,11,2860,135,1917,89,183,1124,176,1112
|
0.9720538608178498,-0.7665478813310426,-0.18172843641255768,-0.8106475789227858,-1.544956106951877,1.9573524101711695,0.4447751115533682,-1.0395551932285616,0.6543867400016848,2.9529597638291984,-1.184096314811162,0.4447751115533682,-0.23791768452069523,-0.33362432918571483,-0.3530834233869732,0.10343536726148002,-1.0160076287643969,2.576604864876466,3.424342931133359,-0.900491564579252,2.0142460639311266,-0.23791768452069523,2.3927379782175318,1.7183433107459631,0.23757265698845073,1.769720066961587,0.25397254379079565
| 3,282
|
Ion transmembrane transporter activity
| 65
| 100
| 2.177445
| 0.029447
|
O43681,O43808,P16615,Q9NW15,Q9UJS0,Q9Y487,P30825,Q8TB61,O95202,Q70HW3,Q15758,P21796,P08195,O75964,Q6NUK1,P21281,Q93050,P98194,P13073,P20674,Q9UM00,Q9Y6M7,Q9H2J7,O95563,P53985,Q9H2D1,Q9C0H2,Q9UBX3,O75746,P24539,P55011,P00403,P36542,P45880,O43826,P41440,Q9HD20,Q9Y619,P36543,P23634,Q8IWT6,Q8TDW0,Q9UDW1,P51798,P11166,P51790,P06576,Q9BVC6,Q93034,Q6KCM7,Q14847,P56385,O43772,Q8N4V1,Q9H9B4,Q8NE86,Q6P4A7,Q13423,Q6P4Q7,P20020,Q96NB2,P12236,Q9H0U3,Q9HC21,Q9Y277
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
639,758,384,391,659,264,138,139,394,13,650,15,270,17,783,778,149,407,153,663,541,416,424,795,544,38,41,167,794,170,293,292,672,50,303,438,188,60,693,565,325,585,68,583,580,331,205,467,732,730,728,215,95,223,752,488,230,238,242,618,503,378,771,772,252
|
3163,793,2686,639,95,758,303,794,2266,17,394,795,292,810,1117,853,205,926,2105,270,1254,2211,580,1255,378,153,2919,384,618,663,778,3176,15,565,170,2179,138,2920,672,693,1789,438,50,1866,1576,331,583,1481,544,293,1359,215,1825,2380,407,1550,2877,1003,238,728,650,938,730,1395,783,2051,230,242,13,325,223,488,139,585,1012,732,149,1589,503,467,41,771,38,424,1405,752,772,188,391,167,68,1690,659,541,252,945,264,60,3220,416
|
-1.5179982112659076,0.47554353945259714,-0.7446984489999219,0.6252443929676549,2.3427776233754467,0.5060299163255124,1.2127112505391577,0.47554353945259714,-0.4320142141361126,3.186489069229093,1.0112796586421209,0.47554353945259714,1.2370139309648251,0.46019487053471625,0.23757265698845073,0.4292836766633106,1.6021706965552707,0.36658921531116717,-0.33362432918571483,1.3323904602126717,0.13746944516855703,-0.3923277640646288,0.6976210318395957,0.13746944516855703,1.0371659946513645,1.918812369361769,-0.9926104125098789,1.0242489935338948,0.6543867400016848,0.5958417361485769,0.4908216973007541,-1.5721074020422647,3.223536276398023,0.7119066464917171,1.7798918673967443,-0.37265087688372656,1.9954018657539796,-0.9926104125098789,0.5810414981125253,0.5661746186246456,-0.18172843641255768,0.9189967934039461,2.7420278978751074,-0.21908700961772024,-0.05405435237037845,1.1511243328250194,0.6976210318395957,-0.0007502583674914466,0.740292053869216,1.2370139309648251,0.06905820401443656,1.5478733691269635,-0.20035758061349548,-0.4923924005392478,0.9982576128879851,-0.03619440570372816,-0.9233040534854985,0.31878600721311506,1.4589593479977,0.5362387937640063,0.6105758605037124,0.36658921531116717,0.5362387937640063,0.05173904046404934,0.4908216973007541,-0.29502699624958933,1.4814285535206084,1.4476634061842635,3.319910808935396,1.1759030599472666,1.5258835277656888,0.8377388499606527,1.976437767564253,0.6976210318395957,0.31878600721311506,0.5362387937640063,1.9381444121492484,-0.05405435237037845,0.8101935073071703,0.8786230124808344,2.877460464329241,0.5060299163255124,2.8844095835048527,0.9720538608178498,0.05173904046404934,0.5211687621279207,0.5060299163255124,1.6870955164987091,1.0242489935338948,1.8102038397505154,2.592048628230388,-0.1081959375724667,0.6105758605037124,0.754392795312904,1.4135270336371222,0.36658921531116717,1.3790121380737033,2.682987626080082,-1.854825017955816,0.9851824752695442
| 3,282
|
Mitochondrial calcium ion transport
| 9
| 16
| 2.167755
| 0.030177
|
Q9BPX6,Q10713,Q8NE86,O95202,P21796,P45880,Q9H300,Q9Y277,Q99623
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
354,227,488,394,15,50,345,252,288
|
2719,394,15,1545,50,227,488,1145,1679,564,288,354,345,868,252,687
|
-0.7665478813310426,1.0112796586421209,3.223536276398023,-0.03619440570372816,2.7420278978751074,1.5037359284595075,0.8377388499606527,0.22109280361990064,-0.1081959375724667,0.7261301615080007,1.2611307098563012,1.1009789242465366,1.1135896288668288,0.4292836766633106,1.4135270336371222,0.5810414981125253
| 3,282
|
Mitochondrial fusion
| 11
| 16
| 2.160884
| 0.030704
|
O60313,Q8N2A8,Q9Y6C9,Q8IWA4,P02786,Q969V5,Q9NX63,Q99536,Q9H300,Q9GZY8,Q8TB36
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
193,191,470,596,240,218,348,251,345,381,679
|
193,1418,240,1878,596,191,679,218,251,381,345,2623,348,868,687,470
|
1.6555243256802743,0.03433177573533618,1.4476634061842635,-0.21908700961772024,0.6832728352514132,1.6766080113317505,0.5810414981125253,1.5478733691269635,1.4135270336371222,1.0371659946513645,1.1135896288668288,-0.6799348090885988,1.1135896288668288,0.4292836766633106,0.5810414981125253,0.8786230124808344
| 3,282
|
Amino-acid transport
| 7
| 8
| 2.15794
| 0.030933
|
Q9H2J7,Q96H78,Q6P4A7,P30825,Q15758,P08195,Q96NB2
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
424,34,230,138,650,270,503
|
270,138,650,230,34,503,424,752
|
1.3323904602126717,1.9954018657539796,0.6105758605037124,1.4814285535206084,2.939384808405215,0.8101935073071703,0.9720538608178498,0.5211687621279207
| 3,282
|
L amino acid transport
| 9
| 12
| 2.154465
| 0.031204
|
Q9H9B4,Q9UJS0,P30825,O75915,Q15758,P08195,O60831,Q9Y619,Q15041
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
752,659,138,484,650,270,528,60,569
|
528,794,484,1601,270,138,569,650,1405,752,659,60
|
0.7684328524082645,0.47554353945259714,0.8377388499606527,-0.07200734605445942,1.3323904602126717,1.9954018657539796,0.7119066464917171,0.6105758605037124,0.05173904046404934,0.5211687621279207,0.6105758605037124,2.682987626080082
| 3,282
|
Carbohydrate derivative transport
| 15
| 18
| 2.14756
| 0.031749
|
O43808,Q8IWT6,Q8TDW0,Q8TB61,P61916,Q9NZJ7,Q6NUK1,P07602,Q8WTV0,Q6KCM7,O43826,P41440,Q9HC21,P12236,Q08722
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
758,325,585,139,840,301,783,209,49,730,303,438,772,378,568
|
2778,758,303,853,209,1255,378,438,840,568,730,783,325,139,585,49,772,301
|
-0.8329007565972378,0.5060299163255124,1.2127112505391577,0.4292836766633106,1.5805666593769274,0.13746944516855703,1.0371659946513645,0.9189967934039461,0.4447751115533682,0.7119066464917171,0.5362387937640063,0.4908216973007541,1.1759030599472666,1.976437767564253,0.6976210318395957,2.749321615614043,0.5060299163255124,1.2248859870045634
| 3,282
|
Cholesterol biosynthesis
| 6
| 16
| 2.142496
| 0.032154
|
Q14739,Q15392,Q15125,Q9UBM7,Q15800,P37268
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
69,135,11,176,89,31
|
2763,833,31,3052,2111,2146,1313,2942,69,11,2860,135,1917,89,183,176
|
-0.8106475789227858,0.4447751115533682,2.9529597638291984,-1.184096314811162,-0.33362432918571483,-0.3530834233869732,0.10343536726148002,-1.0160076287643969,2.576604864876466,3.424342931133359,-0.900491564579252,2.0142460639311266,-0.23791768452069523,2.3927379782175318,1.7183433107459631,1.769720066961587
| 3,282
|
Nuclear inner membrane
| 11
| 19
| 2.14029
| 0.032331
|
P62995,P50402,Q14739,P20700,Q5SNT2,Q9UH99,Q9H1E5,O75844,Q03252,Q99720,Q9BTV4
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
389,261,69,581,561,468,208,80,408,26,609
|
80,616,581,1512,931,261,3102,389,408,1263,69,816,561,964,1274,26,609,208,468
|
2.4499538883891847,0.6543867400016848,0.6976210318395957,-0.018426654504152068,0.36658921531116717,1.3790121380737033,-1.2836932720831662,1.0242489935338948,0.9982576128879851,0.13746944516855703,2.576604864876466,0.46019487053471625,0.7261301615080007,0.35073036585612155,0.13746944516855703,3.006601594300328,0.6688615690298855,1.5913876676796375,0.8786230124808344
| 3,282
|
Inorganic molecular entity transmembrane transporter activity
| 40
| 75
| 2.140254
| 0.032334
|
O43681,P16615,Q9NW15,Q9Y487,O95202,P08195,P21796,O75964,Q93050,P98194,P13073,P20674,Q99797,Q9UM00,Q9Y6M7,Q9H2J7,P55011,Q9C0H2,Q9UBX3,P00403,P24539,P36542,P45880,O43826,Q9HD20,P36543,P23634,Q8IWT6,Q9UDW1,Q8TDW0,P51798,P51790,P06576,P56385,Q8N4V1,Q8NE86,Q13423,Q6P4Q7,P20020,Q9Y277
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
639,384,391,264,394,270,15,17,149,407,153,663,540,541,416,424,293,41,167,292,170,672,50,303,188,693,565,325,68,585,583,331,205,215,223,488,238,242,618,252
|
3163,793,639,303,2266,17,394,292,810,1117,853,205,926,2105,270,1254,2211,1255,153,2919,384,618,663,778,3176,15,565,170,2179,2920,672,693,1789,50,1866,1576,331,583,293,1359,215,1825,2380,407,1550,2877,1003,238,938,1395,242,325,223,488,585,1012,732,149,1589,540,41,771,424,1405,188,391,167,68,1690,541,252,945,264,3220,416
|
-1.5179982112659076,0.47554353945259714,0.6252443929676549,1.2127112505391577,-0.4320142141361126,3.186489069229093,1.0112796586421209,1.2370139309648251,0.46019487053471625,0.23757265698845073,0.4292836766633106,1.6021706965552707,0.36658921531116717,-0.33362432918571483,1.3323904602126717,0.13746944516855703,-0.3923277640646288,0.13746944516855703,1.918812369361769,-0.9926104125098789,1.0242489935338948,0.6543867400016848,0.5958417361485769,0.4908216973007541,-1.5721074020422647,3.223536276398023,0.7119066464917171,1.7798918673967443,-0.37265087688372656,-0.9926104125098789,0.5810414981125253,0.5661746186246456,-0.18172843641255768,2.7420278978751074,-0.21908700961772024,-0.05405435237037845,1.1511243328250194,0.6976210318395957,1.2370139309648251,0.06905820401443656,1.5478733691269635,-0.20035758061349548,-0.4923924005392478,0.9982576128879851,-0.03619440570372816,-0.9233040534854985,0.31878600721311506,1.4589593479977,0.36658921531116717,0.05173904046404934,1.4476634061842635,1.1759030599472666,1.5258835277656888,0.8377388499606527,0.6976210318395957,0.31878600721311506,0.5362387937640063,1.9381444121492484,-0.05405435237037845,0.754392795312904,2.877460464329241,0.5060299163255124,0.9720538608178498,0.05173904046404934,1.6870955164987091,1.0242489935338948,1.8102038397505154,2.592048628230388,-0.1081959375724667,0.754392795312904,1.4135270336371222,0.36658921531116717,1.3790121380737033,-1.854825017955816,0.9851824752695442
| 3,282
|
membrane traffic protein
| 28
| 55
| 2.139659
| 0.032382
|
Q08379,P50570,Q96QK1,P43307,Q9H269,Q56VL3,Q92734,A6NIH7,Q12768,Q9H4M9,O00429,Q9UBC2,Q96PC5,P51572,Q00765,Q9Y2T2,Q9NX40,O60313,Q9HD42,Q8TAG9,Q12907,Q99523,P40855,P11717,Q96A65,Q9UPT5,Q9H223,Q9Y296
|
Functions
|
Panther Protein class
|
panther_protein_class
|
640,894,788,14,918,916,534,32,546,426,808,444,187,313,439,851,192,193,717,597,593,342,351,478,768,375,382,903
|
32,1653,808,1249,1983,193,906,997,1986,1728,478,1257,1736,1819,351,1388,14,2108,894,313,2110,2464,1764,439,640,1829,546,593,916,1057,597,1559,534,768,1612,1644,187,788,342,2647,1719,382,918,426,1036,1567,717,2362,2810,192,2020,444,375,903,851
|
2.9461806183019617,-0.1081959375724667,0.46019487053471625,0.13746944516855703,-0.27588668305362396,1.6555243256802743,0.3823733530740993,0.31878600721311506,-0.27588668305362396,-0.144767223042154,0.8514243186018405,0.13746944516855703,-0.144767223042154,-0.20035758061349548,1.1009789242465366,0.05173904046404934,3.24187118960558,-0.33362432918571483,0.3980834008801064,1.2004894005422622,-0.33362432918571483,-0.553816606593548,-0.1631986289661192,0.9189967934039461,0.6252443929676549,-0.20035758061349548,0.740292053869216,0.6832728352514132,0.3823733530740993,0.28653515071813196,0.6832728352514132,-0.03619440570372816,0.7684328524082645,0.5060299163255124,-0.07200734605445942,-0.09005424964602395,1.6870955164987091,0.4908216973007541,1.1261505340235223,-0.7013933032185452,-0.12643329600044367,1.0371659946513645,0.3823733530740993,0.9588713805429361,0.30269921647967324,-0.03619440570372816,0.5512405638431472,-0.4721516811947069,-0.8329007565972378,1.66608435489872,-0.27588668305362396,0.9189967934039461,1.0500310352209634,0.3980834008801064,0.4447751115533682
| 3,282
|
Cholesterol biosynthesis
| 9
| 18
| 2.136904
| 0.032606
|
Q14739,Q15392,Q15125,Q9UBM7,Q14534,Q15800,O75845,Q16850,P37268
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
69,135,11,176,210,89,405,183,31
|
405,833,31,418,3052,2111,2146,2942,210,69,11,2860,135,1917,89,183,2252,176
|
0.9982576128879851,0.4447751115533682,2.9529597638291984,0.9720538608178498,-1.184096314811162,-0.33362432918571483,-0.3530834233869732,-1.0160076287643969,1.5697074338437027,2.576604864876466,3.424342931133359,-0.900491564579252,2.0142460639311266,-0.23791768452069523,2.3927379782175318,1.7183433107459631,-0.41211517468133246,1.769720066961587
| 3,282
|
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
| 8
| 16
| 2.133571
| 0.032878
|
P05067,Q02818,Q15293,Q06481,Q13217,Q9BTY2,Q07065,O43852
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
169,9,268,362,462,151,121,190
|
190,518,169,1941,1787,1020,834,9,362,121,462,2441,268,1057,861,151
|
1.6766080113317505,0.7824126866297165,1.8001335532224074,-0.25685057969960273,-0.18172843641255768,0.30269921647967324,0.4447751115533682,3.441356884702201,1.0756067086215884,2.106714627386444,0.8786230124808344,-0.5332236662674483,1.3441112138985374,0.28653515071813196,0.4292836766633106,1.9284939850101928
| 3,282
|
Cataract
| 11
| 29
| 2.132235
| 0.032988
|
P48449,P11166,Q15125,O00116,O76024,Q8N2K0,P35579,P08670,Q15800,Q9H6K4,Q9UG56
|
Drugs and Diseases
|
Protein Atlas Disease involvement
|
protein_atlas_disease_involvement
|
418,580,11,493,518,368,619,181,89,93,483
|
493,1181,809,518,3212,181,580,617,619,893,418,3041,1869,2146,11,89,2084,2222,1488,368,964,2156,1713,1344,2057,1721,93,1533,483
|
0.8239953918824245,0.18789041292229028,0.46019487053471625,0.7824126866297165,-1.7965868444906077,1.738998392489689,0.6976210318395957,0.6543867400016848,0.6543867400016848,0.3980834008801064,0.9720538608178498,-1.159609495028328,-0.21908700961772024,-0.3530834233869732,3.424342931133359,2.3927379782175318,-0.3142725349731669,-0.3923277640646288,-0.0007502583674914466,1.0628444846588703,0.35073036585612155,-0.3530834233869732,-0.12643329600044367,0.0862900538235537,-0.29502699624958933,-0.12643329600044367,2.3595270048660506,-0.018426654504152068,0.8514243186018405
| 3,282
|
Abnormal conjunctiva morphology
| 11
| 30
| 2.129256
| 0.033233
|
Q9NW15,Q8IWT6,Q14739,P04066,P10619,Q13510,P02786,P28070,Q9NZ08,P06280,P50851
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
391,325,69,322,72,46,240,115,117,184,474
|
2297,830,240,322,3075,184,72,3114,617,1118,1989,2694,115,1543,2858,1094,1950,3171,474,3012,1829,46,69,1161,325,532,1032,1533,391,117
|
-0.45202600377615704,0.4447751115533682,1.4476634061842635,1.1759030599472666,-1.233560939945348,1.6975470899868141,2.537625343517015,-1.334509459001553,0.6543867400016848,0.23757265698845073,-0.27588668305362396,-0.7446984489999219,2.1339011676066857,-0.03619440570372816,-0.900491564579252,0.25397254379079565,-0.25685057969960273,-1.544956106951877,0.8650522301865151,-1.1111173323671646,-0.20035758061349548,2.792690291492383,2.576604864876466,0.2045322897893938,1.1759030599472666,0.7684328524082645,0.30269921647967324,-0.018426654504152068,1.0242489935338948,2.1339011676066857
| 3,282
|
Abnormal epiphyseal ossification
| 9
| 18
| 2.121033
| 0.033919
|
Q14739,Q96HY6,O75381,Q15125,Q9UBM7,Q7RTS9,P38435,Q9UG56,P40855
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
69,263,330,11,176,239,55,483,351
|
493,1856,2853,330,854,690,55,351,694,1517,69,2637,11,1917,239,263,176,483
|
0.8239953918824245,-0.21908700961772024,-0.900491564579252,1.1511243328250194,0.4292836766633106,0.5661746186246456,2.712662399939541,1.1009789242465366,0.5661746186246456,-0.018426654504152068,2.576604864876466,-0.7013933032185452,3.424342931133359,-0.23791768452069523,1.4589593479977,1.3790121380737033,1.769720066961587,0.8514243186018405
| 3,282
|
Outer mitochondrial membrane protein complex
| 10
| 17
| 2.118855
| 0.034103
|
Q9NS69,Q5XKP0,Q9Y512,Q5HYI7,Q8N4H5,Q15388,Q8IWA4,Q13505,Q9NX63,Q16891
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,570,458,97,5,202,596,25,348,412
|
1571,2075,1000,2938,25,202,412,97,570,651,596,5,2163,0,805,348,458
|
-0.05405435237037845,-0.3142725349731669,0.31878600721311506,-1.0160076287643969,3.0526953443372964,1.6129159816882401,0.9851824752695442,2.325930995779964,0.7119066464917171,0.6105758605037124,0.6832728352514132,3.4806364511034387,-0.3530834233869732,4.030799979701142,0.47554353945259714,1.1135896288668288,0.8921370887005844
| 3,282
|
Intrinsic component of organelle membrane
| 93
| 136
| 2.118684
| 0.034117
|
Q99595,Q9P035,O60830,Q15125,O76024,O15258,Q9Y2R0,Q13505,Q9UM00,Q5SNT2,P04439,Q15629,Q969N2,Q15041,Q5XKP0,Q14739,P42892,Q9Y282,O75844,Q8IWA4,P10321,Q92643,Q9BTV4,Q5HYI7,Q9BWH2,Q99442,P20020,O94901,O95470,Q9BUN8,Q8TB61,Q6UXV4,Q86XL3,O14975,Q8TCT8,O15126,Q8TB36,Q9Y4W6,Q9NQC3,O43505,Q9UBM7,Q8TCT9,O60499,O00767,Q86YN1,O75298,Q15388,Q5J8M3,Q969V5,P13473,Q15070,Q8N4V1,Q9H9B4,P57105,Q6P4A7,Q9BUB7,Q5T9L3,Q96S52,Q9HC21,Q9NPA0,O14925,O43808,P57088,A0FGR8,Q10471,Q9NVH1,Q9H490,Q6ZRP7,O95563,Q96A33,Q86Y82,P49069,O43826,O43292,P51572,Q8IWT6,O95070,Q7L0J3,Q9NX63,Q9BPX6,Q9GZY8,Q9H3K2,P98194,Q16891,Q9Y4P3,O15118,Q16134,Q9Y512,Q9UH99,Q9UG56,O75880,Q8NE86,Q96NB2
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
4,527,10,11,518,517,24,25,541,561,554,51,573,569,570,69,71,78,80,596,587,608,609,97,626,625,618,616,133,134,139,651,142,644,150,660,679,687,165,168,176,178,179,688,195,197,202,729,218,723,216,223,752,226,230,770,245,769,772,256,253,758,779,775,782,805,803,290,795,299,819,308,303,311,313,325,321,332,348,354,381,402,407,412,415,417,440,458,468,483,477,488,503
|
775,2778,688,253,644,417,660,517,311,2688,168,758,1019,303,179,10,197,1571,80,477,518,2075,616,321,1418,133,795,1000,830,554,587,1255,723,618,949,2746,950,2303,2938,71,308,2924,1632,313,1517,779,226,2380,407,1550,782,915,25,1523,69,1264,569,216,11,1231,202,51,440,1964,412,2222,97,729,561,245,570,817,230,651,290,332,861,142,819,195,596,325,2520,2090,223,846,964,488,679,139,150,178,1344,608,573,218,299,1589,503,769,625,4,354,1173,609,770,134,2163,626,2323,381,402,803,752,889,772,1496,256,165,2482,805,348,1689,527,2231,176,483,1039,468,541,78,24,415,687,458,1350
|
0.4908216973007541,-0.8329007565972378,0.5661746186246456,1.402064492860211,0.6105758605037124,0.9720538608178498,0.5958417361485769,0.7824126866297165,1.2004894005422622,-0.7446984489999219,1.8001335532224074,0.5060299163255124,0.30269921647967324,1.2127112505391577,1.738998392489689,3.4356976780399577,1.6236237566684577,-0.05405435237037845,2.4499538883891847,0.8514243186018405,0.7824126866297165,-0.3142725349731669,0.6543867400016848,1.1759030599472666,0.03433177573533618,2.0236236192967936,0.47554353945259714,0.31878600721311506,0.4447751115533682,0.7261301615080007,0.6832728352514132,0.13746944516855703,0.5362387937640063,0.6543867400016848,0.35073036585612155,-0.7885304430072586,0.35073036585612155,-0.45202600377615704,-1.0160076287643969,2.5532811124501102,1.2127112505391577,-0.9926104125098789,-0.09005424964602395,1.2004894005422622,-0.018426654504152068,0.4908216973007541,1.5037359284595075,-0.4923924005392478,0.9982576128879851,-0.03619440570372816,0.4908216973007541,0.3823733530740993,3.0526953443372964,-0.018426654504152068,2.576604864876466,0.13746944516855703,0.7119066464917171,1.5478733691269635,3.424342931133359,0.15435971553016048,1.6129159816882401,2.7273834505609806,0.9189967934039461,-0.25685057969960273,0.9851824752695442,-0.3923277640646288,2.325930995779964,0.5362387937640063,0.7261301615080007,1.4363262187738342,0.7119066464917171,0.46019487053471625,1.4814285535206084,0.6105758605037124,1.2490954003145447,1.1511243328250194,0.4292836766633106,1.9669103320805743,0.46019487053471625,1.634294253015559,0.6832728352514132,1.1759030599472666,-0.5953632204872029,-0.3142725349731669,1.5258835277656888,0.4447751115533682,0.35073036585612155,0.8377388499606527,0.5810414981125253,1.976437767564253,1.9284939850101928,1.7492735352846496,0.0862900538235537,0.6688615690298855,0.7119066464917171,1.5478733691269635,1.2248859870045634,-0.05405435237037845,0.8101935073071703,0.5060299163255124,0.6543867400016848,3.491752883087718,1.1009789242465366,0.2045322897893938,0.6688615690298855,0.5060299163255124,2.0236236192967936,-0.3530834233869732,0.6543867400016848,-0.45202600377615704,1.0371659946513645,1.0112796586421209,0.47554353945259714,0.5211687621279207,0.41371997306172403,0.5060299163255124,-0.0007502583674914466,1.402064492860211,1.8202406866208516,-0.553816606593548,0.47554353945259714,1.1135896288668288,-0.1081959375724667,0.7824126866297165,-0.3923277640646288,1.769720066961587,0.8514243186018405,0.30269921647967324,0.8786230124808344,0.754392795312904,2.4741312253443573,3.065723955038843,0.9851824752695442,0.5810414981125253,0.8921370887005844,0.0862900538235537
| 3,282
|
Aplasia hypoplasia involving the vertebral column
| 6
| 15
| 2.111372
| 0.03474
|
Q8TAA9,Q14739,Q96HY6,O95831,Q7RTS9,P16278
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
101,69,263,237,239,54
|
1782,2853,237,322,854,690,54,893,1387,912,69,1917,239,101,263
|
-0.18172843641255768,-0.900491564579252,1.4589593479977,1.1759030599472666,0.4292836766633106,0.5661746186246456,2.712662399939541,0.3980834008801064,0.05173904046404934,0.3823733530740993,2.576604864876466,-0.23791768452069523,1.4589593479977,2.3089861165903924,1.3790121380737033
| 3,282
|
L alpha amino acid transmembrane transport
| 8
| 11
| 2.108219
| 0.035012
|
Q9UJS0,P30825,O75915,Q15758,P08195,O60831,Q9Y619,Q15041
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
659,138,484,650,270,528,60,569
|
528,794,484,1601,270,138,569,650,1405,659,60
|
0.7684328524082645,0.47554353945259714,0.8377388499606527,-0.07200734605445942,1.3323904602126717,1.9954018657539796,0.7119066464917171,0.6105758605037124,0.05173904046404934,0.6105758605037124,2.682987626080082
| 3,282
|
Protein transporter activity
| 8
| 16
| 2.107957
| 0.035035
|
Q9NS69,Q99595,P49755,O60830,Q15388,Q9Y584,Q9HD20,O14925
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,4,386,10,202,57,188,253
|
253,10,2075,1000,386,3250,2380,398,202,1775,4,188,0,705,57,905
|
1.402064492860211,3.4356976780399577,-0.3142725349731669,0.31878600721311506,1.0242489935338948,-2.321881693407483,-0.4923924005392478,1.0112796586421209,1.6129159816882401,-0.1631986289661192,3.491752883087718,1.6870955164987091,4.030799979701142,0.5661746186246456,2.6904356298930083,0.3980834008801064
| 3,282
|
Nucleotide transport
| 11
| 13
| 2.105672
| 0.035233
|
O43808,Q8IWT6,Q8TDW0,Q9H2D1,Q8TB61,Q6NUK1,Q6KCM7,P41440,Q9HC21,P12236,Q08722
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
758,325,585,38,139,783,730,438,772,378,568
|
758,853,1255,378,438,568,730,783,325,139,585,38,772
|
0.5060299163255124,0.4292836766633106,0.13746944516855703,1.0371659946513645,0.9189967934039461,0.7119066464917171,0.5362387937640063,0.4908216973007541,1.1759030599472666,1.976437767564253,0.6976210318395957,2.8844095835048527,0.5060299163255124
| 3,282
|
Vitamin transport
| 6
| 9
| 2.104327
| 0.03535
|
Q9H2D1,P04062,Q8WTV0,P38435,P41440,O14678
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
38,145,49,55,438,498
|
498,145,580,55,438,49,38,772,945
|
0.8101935073071703,1.9573524101711695,0.6976210318395957,2.712662399939541,0.9189967934039461,2.749321615614043,2.8844095835048527,0.5060299163255124,0.36658921531116717
| 3,282
|
Proton transporting two sector atpase complex
| 7
| 21
| 2.104326
| 0.03535
|
Q15904,P24539,P06576,O75964,Q93050,P56385,Q8N511
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
262,170,205,17,149,215,29
|
471,2266,17,205,778,3176,170,2179,672,693,1789,1576,1359,215,1825,262,29,149,539,1690,264
|
0.8650522301865151,-0.4320142141361126,3.186489069229093,1.6021706965552707,0.4908216973007541,-1.5721074020422647,1.7798918673967443,-0.37265087688372656,0.5810414981125253,0.5661746186246456,-0.18172843641255768,-0.05405435237037845,0.06905820401443656,1.5478733691269635,-0.20035758061349548,1.3790121380737033,2.9932887032618716,1.9381444121492484,0.754392795312904,-0.1081959375724667,1.3790121380737033
| 3,282
|
Abnormal arterial physiology
| 7
| 31
| 2.102168
| 0.035539
|
Q9NWM8,Q14739,P05067,O75844,Q9NZ08,P06280,Q9Y4P3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
355,69,169,80,117,184,415
|
1181,1183,1282,1858,80,830,977,2626,169,184,928,1757,2746,2958,875,2034,1950,2336,1739,1580,69,883,1433,1708,532,355,117,1897,2235,415,1474
|
0.18789041292229028,0.18789041292229028,0.12049491179844807,-0.21908700961772024,2.4499538883891847,0.4447751115533682,0.3347961754544072,-0.7013933032185452,1.8001335532224074,1.6975470899868141,0.36658921531116717,-0.1631986289661192,-0.7885304430072586,-1.0395551932285616,0.41371997306172403,-0.29502699624958933,-0.25685057969960273,-0.4721516811947069,-0.144767223042154,-0.05405435237037845,2.576604864876466,0.41371997306172403,0.03433177573533618,-0.12643329600044367,0.7684328524082645,1.1009789242465366,2.1339011676066857,-0.21908700961772024,-0.3923277640646288,0.9851824752695442,0.01683561215363658
| 3,282
|
External encapsulating structure
| 8
| 28
| 2.09791
| 0.035913
|
P04083,Q53GQ0,Q9NZJ7,Q08380,P07602,P07858,P84157,Q92896
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
377,204,301,271,209,53,249,159
|
1208,2538,377,926,209,53,2105,1190,2212,3007,1020,834,836,2746,2269,1334,1699,2334,1458,813,249,1121,271,421,204,159,1374,301
|
0.17116646162302224,-0.6163193962217591,1.0371659946513645,0.36658921531116717,1.5805666593769274,2.712662399939541,-0.33362432918571483,0.18789041292229028,-0.3923277640646288,-1.1111173323671646,0.30269921647967324,0.4447751115533682,0.4447751115533682,-0.7885304430072586,-0.4320142141361126,0.0862900538235537,-0.12643329600044367,-0.4721516811947069,0.01683561215363658,0.46019487053471625,1.4135270336371222,0.23757265698845073,1.3323904602126717,0.9720538608178498,1.6129159816882401,1.8895785924779709,0.06905820401443656,1.2248859870045634
| 3,282
|
transporter
| 17
| 58
| 2.086635
| 0.036921
|
Q9HD45,Q99595,P53985,Q9H2D1,Q8NFH4,O60830,Q9Y619,Q567V2,Q8N1F7,Q99805,P41440,Q9Y584,O43615,Q15070,P52292,Q12769,O43772
|
Functions
|
Panther Protein class
|
panther_protein_class
|
163,4,544,38,453,10,60,92,274,84,438,57,282,216,317,547,95
|
1724,2171,2974,1620,2327,1330,757,282,639,95,2457,10,1251,1506,1154,1480,1423,438,1333,1994,317,2109,1793,1481,544,1259,1137,3207,567,2380,547,2638,216,92,1395,985,274,453,847,1103,988,767,1493,1107,1236,4,84,2828,2773,38,1614,163,1302,2325,868,57,2295,60
|
-0.144767223042154,-0.37265087688372656,-1.0632548272686395,-0.09005424964602395,-0.4721516811947069,0.0862900538235537,0.5060299163255124,1.2611307098563012,0.6252443929676549,2.3427776233754467,-0.553816606593548,3.4356976780399577,0.13746944516855703,-0.018426654504152068,0.2045322897893938,-0.0007502583674914466,0.03433177573533618,0.9189967934039461,0.0862900538235537,-0.27588668305362396,1.188220112815457,-0.33362432918571483,-0.18172843641255768,-0.0007502583674914466,0.740292053869216,0.13746944516855703,0.22109280361990064,-1.7392183386063267,0.7119066464917171,-0.4923924005392478,0.740292053869216,-0.7013933032185452,1.5478733691269635,2.3761801310307407,0.05173904046404934,0.3347961754544072,1.3206256669684793,0.8921370887005844,0.4447751115533682,0.25397254379079565,0.3347961754544072,0.5060299163255124,-0.0007502583674914466,0.25397254379079565,0.15435971553016048,3.491752883087718,2.4255716705252155,-0.8552914666396761,-0.8106475789227858,2.8844095835048527,-0.07200734605445942,1.850152544618409,0.12049491179844807,-0.45202600377615704,0.4292836766633106,2.6904356298930083,-0.4320142141361126,2.682987626080082
| 3,282
|
Transport of inorganic cations anions and amino acids oligopeptides
| 6
| 11
| 2.084425
| 0.037122
|
P55011,Q9UBX3,P30825,Q70HW3,P08195,Q9Y6M7
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
293,167,138,13,270,416
|
270,2789,138,293,650,13,1012,424,1405,167,416
|
1.3323904602126717,-0.8329007565972378,1.9954018657539796,1.2370139309648251,0.6105758605037124,3.319910808935396,0.31878600721311506,0.9720538608178498,0.05173904046404934,1.8102038397505154,0.9851824752695442
| 3,282
|
Ventricular preexcitation
| 6
| 8
| 2.081933
| 0.037349
|
P00403,P03886,O75306,P10253,P13473,P03915
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
292,75,267,372,723,721
|
738,267,292,75,721,372,723,1320
|
0.5211687621279207,1.3441112138985374,1.2370139309648251,2.506054203043081,0.5362387937640063,1.0500310352209634,0.5362387937640063,0.10343536726148002
| 3,282
|
Sphingolipid pathway
| 6
| 9
| 2.070843
| 0.038373
|
O15269,O95470,Q13510,P04062,Q06136,Q96G23
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
257,133,46,145,120,90
|
257,1380,133,145,3199,120,46,448,90
|
1.390559620323408,0.05173904046404934,2.0236236192967936,1.9573524101711695,-1.6826967390281786,2.1158046507689834,2.792690291492383,0.9055948775740706,2.3844709040308296
| 3,282
|
Organophosphate ester transmembrane transporter activity
| 10
| 12
| 2.05886
| 0.039508
|
O43808,Q8IWT6,Q9H2D1,Q8TB61,Q6NUK1,Q6KCM7,O43826,P41440,Q9HC21,P12236
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
758,325,38,139,783,730,303,438,772,378
|
758,303,853,1255,378,438,730,783,325,139,38,772
|
0.5060299163255124,1.2127112505391577,0.4292836766633106,0.13746944516855703,1.0371659946513645,0.9189967934039461,0.5362387937640063,0.4908216973007541,1.1759030599472666,1.976437767564253,2.8844095835048527,0.5060299163255124
| 3,282
|
N glycan biosynthesis
| 12
| 17
| 2.056947
| 0.039691
|
Q86YN1,Q9UKM7,Q16706,O60762,P04843,P61803,P46977,Q8TCJ2,Q9BV10,Q13724,Q9BT22,Q2TAA5
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
195,350,451,578,485,741,373,638,248,155,515,858
|
578,1284,485,873,1075,373,741,155,1361,451,858,195,638,515,248,350,1114
|
0.6976210318395957,0.12049491179844807,0.8377388499606527,0.41371997306172403,0.2702931493830407,1.0500310352209634,0.5211687621279207,1.9090993860580008,0.06905820401443656,0.8921370887005844,0.4292836766633106,1.634294253015559,0.6398478494370026,0.7963327544291974,1.4249475180109552,1.1135896288668288,0.25397254379079565
| 3,282
|
Increased bone mineral density
| 8
| 25
| 2.052403
| 0.040131
|
Q14108,P48651,Q14739,Q15392,Q15125,Q13126,P04062,P54802
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
3,323,69,135,11,76,145,185
|
1282,977,145,617,1118,3133,2694,1543,2034,323,583,185,2895,1739,3185,76,1122,3,69,883,11,135,2315,1897,415
|
0.12049491179844807,0.3347961754544072,1.9573524101711695,0.6543867400016848,0.23757265698845073,-1.3860262152164,-0.7446984489999219,-0.03619440570372816,-0.29502699624958933,1.1759030599472666,0.6976210318395957,1.6975470899868141,-0.9462602777918803,-0.144767223042154,-1.5994545700709446,2.506054203043081,0.23757265698845073,3.4972936020541496,2.576604864876466,0.41371997306172403,3.424342931133359,2.0142460639311266,-0.45202600377615704,-0.21908700961772024,0.9851824752695442
| 3,282
|
Glycolipid biosynthetic process
| 7
| 9
| 2.052337
| 0.040137
|
O60762,Q96S52,Q99805,O43292,Q969N2,Q8NBX0,Q92643
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
578,769,84,311,573,28,608
|
311,578,1313,28,608,573,769,84,803
|
1.2004894005422622,0.6976210318395957,0.10343536726148002,2.9999531979248477,0.6688615690298855,0.7119066464917171,0.5060299163255124,2.4255716705252155,0.47554353945259714
| 3,282
|
Regulation of cellular ph
| 9
| 21
| 2.048714
| 0.04049
|
O75503,Q15904,Q9Y487,P51790,P50897,P06576,Q93050,Q8N511,Q9Y6M7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
36,262,264,331,44,205,149,29,416
|
36,471,1331,205,2267,44,1632,331,1825,262,29,940,988,1012,149,1032,3085,1690,264,3220,416
|
2.898255890365687,0.8650522301865151,0.0862900538235537,1.6021706965552707,-0.4320142141361126,2.8635099094119285,-0.09005424964602395,1.1511243328250194,-0.20035758061349548,1.3790121380737033,2.9932887032618716,0.36658921531116717,0.3347961754544072,0.31878600721311506,1.9381444121492484,0.30269921647967324,-1.233560939945348,-0.1081959375724667,1.3790121380737033,-1.854825017955816,0.9851824752695442
| 3,282
|
Regulation of ph
| 9
| 21
| 2.048714
| 0.04049
|
O75503,Q15904,Q9Y487,P51790,P50897,P06576,Q93050,Q8N511,Q9Y6M7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
36,262,264,331,44,205,149,29,416
|
36,471,1331,205,2267,44,1632,331,1825,262,29,940,988,1012,149,1032,3085,1690,264,3220,416
|
2.898255890365687,0.8650522301865151,0.0862900538235537,1.6021706965552707,-0.4320142141361126,2.8635099094119285,-0.09005424964602395,1.1511243328250194,-0.20035758061349548,1.3790121380737033,2.9932887032618716,0.36658921531116717,0.3347961754544072,0.31878600721311506,1.9381444121492484,0.30269921647967324,-1.233560939945348,-0.1081959375724667,1.3790121380737033,-1.854825017955816,0.9851824752695442
| 3,282
|
Bilateral sensorineural hearing impairment
| 13
| 28
| 2.038436
| 0.041506
|
O43681,Q15067,P55011,P00403,P35637,P03915,Q7Z406,P03886,Q9NZJ7,P07602,P18074,Q13217,P38159
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
639,419,293,292,297,721,653,75,301,209,617,462,186
|
639,292,75,721,209,1731,617,1118,2694,1543,297,186,2306,2335,293,2895,763,2563,462,1122,419,1528,653,1645,1924,1533,301,2580
|
0.6252443929676549,1.2370139309648251,2.506054203043081,0.5362387937640063,1.5805666593769274,-0.144767223042154,0.6543867400016848,0.23757265698845073,-0.7446984489999219,-0.03619440570372816,1.2248859870045634,1.6870955164987091,-0.45202600377615704,-0.4721516811947069,1.2370139309648251,-0.9462602777918803,0.5060299163255124,-0.6373991838940739,0.8786230124808344,0.23757265698845073,0.9720538608178498,-0.018426654504152068,0.6105758605037124,-0.09005424964602395,-0.23791768452069523,-0.018426654504152068,1.2248859870045634,-0.6373991838940739
| 3,282
|
Sterol biosynthesis
| 6
| 18
| 2.038398
| 0.04151
|
Q14739,Q15392,Q15125,Q9UBM7,Q15800,P37268
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
69,135,11,176,89,31
|
405,2763,833,31,3052,2111,2146,1313,2942,69,11,2860,135,1917,89,183,176,1980
|
0.9982576128879851,-0.8106475789227858,0.4447751115533682,2.9529597638291984,-1.184096314811162,-0.33362432918571483,-0.3530834233869732,0.10343536726148002,-1.0160076287643969,2.576604864876466,3.424342931133359,-0.900491564579252,2.0142460639311266,-0.23791768452069523,2.3927379782175318,1.7183433107459631,1.769720066961587,-0.25685057969960273
| 3,282
|
Disproportionate short limb short stature
| 13
| 21
| 2.036289
| 0.041721
|
O75718,Q32P28,Q14739,Q15392,Q8WVQ1,Q15125,P42345,O00116,Q9UBM7,Q7RTS9,P10644,Q9BV10,Q7LGA3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
603,421,69,135,199,11,673,493,176,239,690,248,158
|
493,809,2853,603,690,2837,673,1791,742,69,11,135,421,1010,158,239,1712,199,2572,248,176
|
0.8239953918824245,0.46019487053471625,-0.900491564579252,0.6688615690298855,0.5661746186246456,-0.8778212232244633,0.5810414981125253,-0.18172843641255768,0.5211687621279207,2.576604864876466,3.424342931133359,2.0142460639311266,0.9720538608178498,0.31878600721311506,1.8895785924779709,1.4589593479977,-0.12643329600044367,1.6236237566684577,-0.6373991838940739,1.4249475180109552,1.769720066961587
| 3,282
|
Abnormality of corneal size
| 10
| 42
| 2.034465
| 0.041905
|
Q8NCH0,Q9NWM8,O43505,O95202,Q15125,Q96EK5,P36404,O75845,Q13045,O96028
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,355,168,394,11,300,18,405,314,376
|
2137,168,1282,2173,2101,405,394,376,2176,617,1118,2694,1543,2378,2034,18,1821,2036,812,1739,1580,314,3203,1915,1460,883,11,1056,1771,2319,2881,65,300,1721,2199,1497,355,1897,973,806,415,946
|
-0.3530834233869732,1.8001335532224074,0.12049491179844807,-0.37265087688372656,-0.33362432918571483,0.9982576128879851,1.0112796586421209,1.0371659946513645,-0.37265087688372656,0.6543867400016848,0.23757265698845073,-0.7446984489999219,-0.03619440570372816,-0.4923924005392478,-0.29502699624958933,3.186489069229093,-0.20035758061349548,-0.29502699624958933,0.46019487053471625,-0.144767223042154,-0.05405435237037845,1.2004894005422622,-1.7108530645839468,-0.23791768452069523,0.01683561215363658,0.41371997306172403,3.424342931133359,0.28653515071813196,-0.1631986289661192,-0.45202600377615704,-0.9233040534854985,2.615058180509215,1.2248859870045634,-0.12643329600044367,-0.37265087688372656,-0.0007502583674914466,1.1009789242465366,-0.21908700961772024,0.35073036585612155,0.47554353945259714,0.9851824752695442,0.36658921531116717
| 3,282
|
L amino acid transmembrane transporter activity
| 6
| 8
| 2.029847
| 0.042372
|
Q9H9B4,Q9UJS0,P30825,Q15758,P08195,Q9Y619
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
752,659,138,650,270,60
|
794,270,138,650,1405,752,659,60
|
0.47554353945259714,1.3323904602126717,1.9954018657539796,0.6105758605037124,0.05173904046404934,0.5211687621279207,0.6105758605037124,2.682987626080082
| 3,282
|
mitochondria
| 7
| 11
| 2.026549
| 0.042709
|
Q15388,P21796,Q8IWA4,P45880,Q9NR31,Q969Q5,Q9Y277
|
Localization
|
OpenCell Localization
|
opencell_localization
|
202,15,596,50,704,574,252
|
2075,1418,15,50,1523,202,596,574,704,805,252
|
-0.3142725349731669,0.03433177573533618,3.223536276398023,2.7420278978751074,-0.018426654504152068,1.6129159816882401,0.6832728352514132,0.7119066464917171,0.5661746186246456,0.47554353945259714,1.4135270336371222
| 3,282
|
serine protease
| 8
| 18
| 2.012108
| 0.044209
|
P10619,P67812,Q9HB40,O14773,Q4J6C6,Q9H3G5,P42785,Q9H300
|
Functions
|
Panther Protein class
|
panther_protein_class
|
72,106,12,81,338,19,20,345
|
81,72,3156,1944,2584,893,20,1910,106,559,338,2007,368,3145,345,19,12,2579
|
2.4255716705252155,2.537625343517015,-1.491231286058741,-0.25685057969960273,-0.6586038820934165,0.3980834008801064,3.142617455562031,-0.23791768452069523,2.2747975061979706,0.7261301615080007,1.1261505340235223,-0.27588668305362396,1.0628444846588703,-1.4120526914832512,1.1135896288668288,3.1740265138691703,3.343473503126647,-0.6373991838940739
| 3,282
|
Nucleotide transmembrane transporter activity
| 9
| 11
| 2.010334
| 0.044396
|
O43808,Q8IWT6,Q9H2D1,Q8TB61,Q6NUK1,Q6KCM7,P41440,Q9HC21,P12236
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
758,325,38,139,783,730,438,772,378
|
758,853,1255,378,438,730,783,325,139,38,772
|
0.5060299163255124,0.4292836766633106,0.13746944516855703,1.0371659946513645,0.9189967934039461,0.5362387937640063,0.4908216973007541,1.1759030599472666,1.976437767564253,2.8844095835048527,0.5060299163255124
| 3,282
|
Phospholipid metabolism
| 12
| 18
| 1.997849
| 0.045733
|
Q9NUQ2,P48651,P35790,Q9HCL2,Q9NPH0,O95674,Q92604,Q9BVG9,O14735,Q6UWP7,Q96N66,Q9UG56
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
347,323,105,823,112,646,701,374,776,500,315,483
|
776,646,105,323,500,885,1398,1203,701,1033,315,1402,374,823,112,2480,347,483
|
0.4908216973007541,0.6105758605037124,2.2747975061979706,1.1759030599472666,0.8101935073071703,0.41371997306172403,0.05173904046404934,0.18789041292229028,0.5661746186246456,0.30269921647967324,1.2004894005422622,0.05173904046404934,1.0500310352209634,0.46019487053471625,2.1608393713191574,-0.553816606593548,1.1135896288668288,0.8514243186018405
| 3,282
|
Protein transmembrane import into intracellular organelle
| 6
| 15
| 1.996139
| 0.045919
|
Q99595,O60830,Q15388,O95831,O43615,O14925
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,10,202,237,282,253
|
253,282,1856,10,330,2075,237,1000,2891,694,202,960,1747,4,2868
|
1.402064492860211,1.2611307098563012,-0.21908700961772024,3.4356976780399577,1.1511243328250194,-0.3142725349731669,1.4589593479977,0.31878600721311506,-0.9462602777918803,0.5661746186246456,1.6129159816882401,0.35073036585612155,-0.144767223042154,3.491752883087718,-0.900491564579252
| 3,282
|
Purine nucleotide transport
| 9
| 11
| 1.99546
| 0.045993
|
O43808,Q8IWT6,Q8TDW0,Q8TB61,Q6NUK1,Q6KCM7,P41440,P12236,Q08722
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
758,325,585,139,783,730,438,378,568
|
758,853,1255,378,438,568,730,783,325,139,585
|
0.5060299163255124,0.4292836766633106,0.13746944516855703,1.0371659946513645,0.9189967934039461,0.7119066464917171,0.5362387937640063,0.4908216973007541,1.1759030599472666,1.976437767564253,0.6976210318395957
| 3,282
|
Hydrogen ion transport
| 6
| 18
| 1.994946
| 0.046049
|
Q15904,P24539,P06576,O75964,Q93050,P56385
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
262,170,205,17,149,215
|
2266,17,205,778,3176,170,2179,672,693,1789,1576,1359,215,1825,262,149,1690,264
|
-0.4320142141361126,3.186489069229093,1.6021706965552707,0.4908216973007541,-1.5721074020422647,1.7798918673967443,-0.37265087688372656,0.5810414981125253,0.5661746186246456,-0.18172843641255768,-0.05405435237037845,0.06905820401443656,1.5478733691269635,-0.20035758061349548,1.3790121380737033,1.9381444121492484,-0.1081959375724667,1.3790121380737033
| 3,282
|
Abnormal choroid morphology
| 13
| 29
| 1.99467
| 0.046079
|
Q01082,Q5XKP0,Q10713,Q12768,O43505,O75381,P53701,P04439,P52732,O60826,Q9Y619,P50542,P40855
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
763,570,227,546,168,330,877,554,812,403,60,694,351
|
1208,168,1856,1353,403,330,1696,2908,554,1735,875,351,2078,1821,694,812,877,1517,763,1869,227,546,570,1032,1885,2865,1244,60,1474
|
0.17116646162302224,1.8001335532224074,-0.21908700961772024,0.06905820401443656,0.9982576128879851,1.1511243328250194,-0.12643329600044367,-0.9693618509410136,0.7261301615080007,-0.144767223042154,0.41371997306172403,1.1009789242465366,-0.3142725349731669,-0.20035758061349548,0.5661746186246456,0.46019487053471625,0.41371997306172403,-0.018426654504152068,0.5060299163255124,-0.21908700961772024,1.5037359284595075,0.740292053869216,0.7119066464917171,0.30269921647967324,-0.21908700961772024,-0.900491564579252,0.15435971553016048,2.682987626080082,0.01683561215363658
| 3,282
|
Steroid biosynthesis
| 9
| 24
| 1.993892
| 0.046164
|
Q14739,Q15392,Q53GQ0,Q15125,Q9UBM7,Q15800,O75845,Q16850,P37268
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
69,135,204,11,176,89,405,183,31
|
405,2763,833,31,418,3052,2111,2146,1313,2942,69,11,2860,135,1917,89,183,204,1062,3228,2360,1685,176,1980
|
0.9982576128879851,-0.8106475789227858,0.4447751115533682,2.9529597638291984,0.9720538608178498,-1.184096314811162,-0.33362432918571483,-0.3530834233869732,0.10343536726148002,-1.0160076287643969,2.576604864876466,3.424342931133359,-0.900491564579252,2.0142460639311266,-0.23791768452069523,2.3927379782175318,1.7183433107459631,1.6129159816882401,0.28653515071813196,-1.9438648937139937,-0.4721516811947069,-0.1081959375724667,1.769720066961587,-0.25685057969960273
| 3,282
|
Subsets and Splits
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