term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
RNA-binding domain superfamily [IPR035979]
| 56
| 134
| 2.839184
| 0.004523
|
P51991,P33240,O43347,Q8WXF1,Q15056,Q96T37,P31942,Q8IXT5,P35637,P52597,P52272,P11940,P98175,Q13242,P38159,P23246,Q86V81,Q14011,O14979,Q9UKM9,P62995,Q16629,Q15233,Q8NFH5,P52756,Q9Y3A4,Q92804,P22626,Q13151,Q01844,Q9UKA9,O75494,P31943,P55795,Q96PK6,Q9Y5S9,Q15427,P43243,Q14103,O15047,A0AV96,O60506,Q8N684,P52298,O43390,P31483,Q07955,Q99729,Q8WUA2,P23588,O95453,Q13595,P07910,Q9BWF3,P98179,Q01085
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
377,508,372,393,758,797,142,534,150,281,656,655,528,529,161,288,564,168,169,572,303,561,560,308,430,711,187,317,558,190,459,445,201,204,334,743,469,466,340,586,460,225,485,722,229,358,481,234,767,617,365,498,367,383,123,378
|
460,1869,169,1463,586,372,229,1515,225,445,2145,2016,365,1878,367,1345,1197,983,782,655,1881,1883,987,317,288,617,1470,1242,358,142,201,508,150,161,2526,466,2088,377,656,722,281,430,204,1074,303,875,528,123,1894,378,190,3250,2937,481,1532,917,1422,558,529,2406,1079,1425,1253,498,168,340,1163,1589,1826,2274,758,560,2896,1828,469,1041,561,1829,2542,1771,1650,2111,1085,564,1652,534,851,2851,485,308,767,1842,2612,393,2663,187,1376,1496,1445,1551,334,797,2421,234,2422,1271,383,2055,1503,2126,1013,893,1668,2295,1276,1452,1509,1559,1230,2129,2180,459,572,1795,2917,3278,2003,2867,1737,711,931,1866,743,977
|
0.7293444986172449,-0.21582458354418593,1.8026650560757604,-0.029937337355577215,0.5661520429850156,0.9106055997578559,1.444713076909665,-0.05613225744942473,1.4651460309893183,0.7523010836930542,-0.32478217017330907,-0.2700467318806754,0.9328873923979636,-0.21582458354418593,0.9328873923979636,0.02210297651221063,0.09930691761130685,0.22576972351761432,0.3740380583531353,0.4948313489884187,-0.21582458354418593,-0.21582458354418593,0.22576972351761432,1.0648954266698725,1.1941177625102746,0.5424727361776948,-0.029937337355577215,0.07368496760344917,0.9550879611029554,2.0304811478621976,1.6460928822167984,0.6599460191541926,1.9554475850393123,1.8603914432017374,-0.4921810762200194,0.7293444986172449,-0.2973496050355208,0.9106055997578559,0.4948313489884187,0.42264946952153903,1.236595433267566,0.7979543947770469,1.6262442098001728,0.1755097373274426,1.129846507529864,0.3003674196569163,0.6366343901410989,2.2684240002799623,-0.21582458354418593,0.9106055997578559,1.7052650235202231,-1.0572995486724805,-0.7232842213033084,0.706300299890814,-0.05613225744942473,0.2756058236423961,-0.0038593161671487642,0.6132320530882964,0.6366343901410989,-0.43583767226307185,0.1755097373274426,-0.0038593161671487642,0.07368496760344917,0.6831677294955423,1.8219658343840837,0.99924807807911,0.12481764303170995,-0.08244526537605792,-0.18890262528843013,-0.38004199286570056,0.39839338050516404,0.6132320530882964,-0.6938776197516214,-0.18890262528843013,0.7293444986172449,0.20069322429525754,0.6132320530882964,-0.18890262528843013,-0.4921810762200194,-0.16210499188174082,-0.10887756899447036,-0.2973496050355208,0.1755097373274426,0.6132320530882964,-0.10887756899447036,0.6366343901410989,0.32502601874310844,-0.6646226489620753,0.706300299890814,1.1082724828312556,0.39839338050516404,-0.18890262528843013,-0.5205619963614778,0.888241909646759,-0.5490844868874409,1.7444059316466967,0.02210297651221063,-0.029937337355577215,-0.0038593161671487642,-0.05613225744942473,1.021208931090401,0.3740380583531353,-0.43583767226307185,1.4242127921315773,-0.43583767226307185,0.07368496760344917,0.9106055997578559,-0.2700467318806754,-0.029937337355577215,-0.2973496050355208,0.22576972351761432,0.3003674196569163,-0.10887756899447036,-0.38004199286570056,0.07368496760344917,-0.0038593161671487642,-0.029937337355577215,-0.05613225744942473,0.09930691761130685,-0.2973496050355208,-0.32478217017330907,0.7523010836930542,0.6132320530882964,-0.16210499188174082,-0.6938776197516214,-1.088674970956618,-0.24287217557351562,-0.6646226489620753,-0.13543039550688563,0.44680723292840124,0.2756058236423961,-0.18890262528843013,0.42264946952153903,0.2507402549882607
| 3,447
|
Cardiac muscle contraction
| 9
| 22
| 2.827877
| 0.004686
|
P14406,P13073,P16615,P20674,O14949,P00403,P08574,Q9UDW1,P09669
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
0,250,390,417,108,338,463,124,406
|
108,338,551,836,2251,463,715,406,1069,250,0,1116,942,390,417,806,1158,753,1353,1416,1356,124
|
2.4105871078712475,0.99924807807911,0.6132320530882964,0.32502601874310844,-0.38004199286570056,0.7293444986172449,0.42264946952153903,0.8432660990380526,0.1755097373274426,1.3206836082734048,6.3352481246556165,0.15021822725387687,0.2507402549882607,0.888241909646759,0.8206525871716301,0.3495825824320858,0.12481764303170995,0.39839338050516404,0.02210297651221063,-0.0038593161671487642,0.02210297651221063,2.232387500674451
| 3,447
|
Protein transmembrane transport
| 10
| 25
| 2.827803
| 0.004687
|
Q15629,Q99595,P31751,O95831,Q15388,P49755,O14925,Q9NS69,O43615,O60830
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,32,375,373,139,399,240,19,212,57
|
240,212,57,864,446,373,714,2254,985,375,399,2697,2533,914,678,139,128,1167,2801,1782,1661,32,968,19,670
|
1.3830082140752036,1.5663180339062512,3.0782810890943333,0.3003674196569163,0.7523010836930542,0.9106055997578559,0.42264946952153903,-0.38004199286570056,0.22576972351761432,0.9106055997578559,0.8657956397936897,-0.5777501510624806,-0.4921810762200194,0.2756058236423961,0.4708675653967537,2.067668972449665,2.1597019144209066,0.12481764303170995,-0.6355175563328855,-0.16210499188174082,-0.10887756899447036,3.5234451642020086,0.2507402549882607,3.856733849716352,0.4948313489884187
| 3,447
|
Molecular transducer activity
| 9
| 42
| 2.826587
| 0.004705
|
Q15629,P49327,O15118,P30536,Q14108,Q8WTV0,Q07954,O15173,Q99720
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,132,67,6,70,16,154,91,63
|
1062,2517,67,91,2194,3282,3179,2315,507,3012,2257,717,6,1888,2590,132,1307,2465,154,2157,3345,1481,70,1310,128,759,1364,532,2948,16,255,2764,1661,1223,63,705,2298,2507,504,670,648,1019
|
0.1755097373274426,-0.4921810762200194,2.885003643625329,2.6010990317026987,-0.3523458255088766,-1.1202280506221005,-0.9642170344811924,-0.4078721182203763,0.6599460191541926,-0.782559488471584,-0.38004199286570056,0.42264946952153903,4.542704790332735,-0.21582458354418593,-0.5205619963614778,2.141400980540596,0.04795069293778851,-0.46394015097449753,1.9175959588678502,-0.32478217017330907,-1.2482633580866476,-0.029937337355577215,2.8522335346715137,0.04795069293778851,2.1597019144209066,0.39839338050516404,0.02210297651221063,0.6366343901410989,-0.7232842213033084,3.95501878428734,1.3206836082734048,-0.6065606205962223,-0.10887756899447036,0.09930691761130685,2.966223445923369,0.44680723292840124,-0.38004199286570056,-0.46394015097449753,0.6831677294955423,0.4948313489884187,0.5186994533961014,0.22576972351761432
| 3,447
|
Nuclear inner membrane
| 12
| 23
| 2.819486
| 0.00481
|
O75844,Q13185,Q9H1E5,O76062,P20700,P62995,Q14728,Q8IXM6,Q03252,P50402,P43243,Q99720
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
64,511,194,165,479,303,499,434,432,467,466,63
|
64,165,1148,479,1699,466,467,873,303,432,511,499,727,2109,1128,434,1318,3063,63,1662,194,611,1737
|
2.9500592169623037,1.8412078293006888,0.12481764303170995,0.706300299890814,-0.13543039550688563,0.7293444986172449,0.7293444986172449,0.3003674196569163,1.129846507529864,0.7979543947770469,0.6599460191541926,0.6831677294955423,0.42264946952153903,-0.2973496050355208,0.15021822725387687,0.7979543947770469,0.04795069293778851,-0.812431823101089,2.966223445923369,-0.10887756899447036,1.685602847740683,0.5661520429850156,-0.13543039550688563
| 3,447
|
Protease
| 24
| 89
| 2.811776
| 0.004927
|
Q86TI2,O75976,Q4J6C6,Q9UIQ6,Q92905,P42892,Q7Z2K6,Q9HB40,Q9BYT8,Q96K76,P28072,P42785,Q96RU2,O75844,Q2T9J0,Q9NZ08,Q6P179,P10619,P09960,Q5JRX3,P55786,Q99797,P67812,Q16740
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
137,266,412,23,286,37,40,48,436,435,54,55,310,64,192,198,450,72,447,470,90,232,241,116
|
1683,2680,548,1516,804,64,266,834,3178,654,1630,447,72,3328,2197,2739,54,694,3080,3123,752,1526,2784,55,37,1700,2693,1949,1161,1476,1527,2030,912,1575,90,871,241,3376,1076,1825,1536,2942,1164,1361,116,192,412,470,1902,450,1129,3401,40,137,2281,2223,852,488,286,2807,1049,3422,3142,1096,435,2712,310,1052,967,3389,232,436,773,668,3113,1791,1183,48,1330,2673,1859,2863,198,3169,23,2302,3041,976,2962
|
-0.13543039550688563,-0.5777501510624806,0.6132320530882964,-0.05613225744942473,0.3495825824320858,2.9500592169623037,1.278782566805988,0.32502601874310844,-0.9642170344811924,0.4948313489884187,-0.10887756899447036,0.7523010836930542,2.8027703309462138,-1.2159763235501515,-0.3523458255088766,-0.6065606205962223,3.1257323641454624,0.44680723292840124,-0.8424631282046733,-0.9030103721202933,0.39839338050516404,-0.05613225744942473,-0.6355175563328855,3.109952884310997,3.4487695757462786,-0.13543039550688563,-0.5777501510624806,-0.24287217557351562,0.12481764303170995,-0.029937337355577215,-0.05613225744942473,-0.2700467318806754,0.2756058236423961,-0.08244526537605792,2.635145909771866,0.3003674196569163,1.3830082140752036,-1.4125933300875322,0.1755097373274426,-0.18890262528843013,-0.05613225744942473,-0.7232842213033084,0.12481764303170995,0.02210297651221063,2.3398971923183667,1.685602847740683,0.8432660990380526,0.7293444986172449,-0.21582458354418593,0.7523010836930542,0.15021822725387687,-1.5819950927603335,3.3732566413381613,2.0861819039271947,-0.38004199286570056,-0.3523458255088766,0.32502601874310844,0.706300299890814,1.2153931970579401,-0.6355175563328855,0.20069322429525754,-1.828385870613889,-0.9030103721202933,0.1755097373274426,0.7979543947770469,-0.5777501510624806,1.1082724828312556,0.20069322429525754,0.2507402549882607,-1.479725735965493,1.444713076909665,0.7979543947770469,0.39839338050516404,0.4948313489884187,-0.8726553252537929,-0.16210499188174082,0.12481764303170995,3.31222899499851,0.04795069293778851,-0.5490844868874409,-0.18890262528843013,-0.6646226489620753,1.6658789469386504,-0.933530264018968,3.699372205651011,-0.38004199286570056,-0.782559488471584,0.2507402549882607,-0.7232842213033084
| 3,447
|
Abnormal activity of mitochondrial respiratory chain
| 11
| 53
| 2.809511
| 0.004962
|
Q70HW3,Q96CU9,Q9UBX3,Q86Y39,O75306,P21912,P03886,Q9P0J0,Q9Y6M9,Q9Y2R0,O43676
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,4,199,230,105,236,15,184,257,27,29
|
2439,1111,29,1872,3359,1518,105,2578,1687,980,2015,713,15,1879,250,2080,417,236,3079,3014,2400,1699,2692,3331,721,695,2532,597,3195,2216,3108,1167,997,2279,35,230,1320,4,966,644,1500,1272,1014,473,583,2622,184,2433,199,27,712,2919,257
|
-0.46394015097449753,0.15021822725387687,3.5973040673963035,-0.21582458354418593,-1.3462719949496813,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,-0.13543039550688563,0.22576972351761432,-0.2700467318806754,0.42264946952153903,3.9689451889376715,-0.21582458354418593,1.3206836082734048,-0.2973496050355208,0.8206525871716301,1.4036446740202682,-0.8424631282046733,-0.782559488471584,-0.43583767226307185,-0.13543039550688563,-0.5777501510624806,-1.2159763235501515,0.42264946952153903,0.44680723292840124,-0.4921810762200194,0.5661520429850156,-0.9642170344811924,-0.3523458255088766,-0.8726553252537929,0.12481764303170995,0.22576972351761432,-0.38004199286570056,3.478739117626629,1.444713076909665,0.04795069293778851,4.904690951021535,0.2507402549882607,0.5186994533961014,-0.029937337355577215,0.07368496760344917,0.22576972351761432,0.7293444986172449,0.5897382077871124,-0.5205619963614778,1.7638855180459252,-0.43583767226307185,1.6658789469386504,3.6558165597384233,0.44680723292840124,-0.6938776197516214,1.3206836082734048
| 3,447
|
Membrane lipid biosynthetic process
| 7
| 25
| 2.800205
| 0.005107
|
Q8NBX0,O95470,Q06136,Q96G23,P04062,P27544,Q16880
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,33,109,148,245,60,253
|
685,1113,1063,33,245,3097,1885,60,2894,109,2161,2102,253,1430,793,65,488,1548,148,582,277,1670,972,1557,671
|
0.44680723292840124,0.15021822725387687,0.1755097373274426,3.5085760309399507,1.341528204791294,-0.8726553252537929,-0.21582458354418593,2.9823482482966575,-0.6938776197516214,2.3929870039150383,-0.32478217017330907,-0.2973496050355208,1.3206836082734048,-0.0038593161671487642,0.3740380583531353,2.9500592169623037,0.706300299890814,-0.05613225744942473,1.9930749898852833,0.5897382077871124,1.2577250368668513,-0.10887756899447036,0.2507402549882607,-0.05613225744942473,0.4948313489884187
| 3,447
|
Amide binding
| 33
| 105
| 2.79764
| 0.005148
|
P40939,P21796,P49327,P45880,Q15388,P04818,P10321,Q8WTV0,Q9UM22,Q15392,Q9UIQ6,Q07954,P24390,P42892,O00264,Q9H7Z7,Q9BYT8,P00374,Q9NQX7,O43731,Q9H3P7,Q9NZ08,Q6P179,O94826,P49748,P07602,P55786,P10909,Q9Y680,Q99735,Q02252,P41440,Q9NXR7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
376,3,132,7,139,397,398,16,146,147,23,154,36,37,300,438,436,51,314,188,322,198,450,446,86,339,90,222,97,362,243,119,387
|
2569,1143,300,1110,2440,3436,548,2821,3281,188,979,2072,3006,446,51,3432,524,397,3428,339,1520,906,398,222,3431,2197,3414,3,2081,3151,36,1030,1471,3051,2690,1032,947,1117,2201,948,376,119,37,2262,7,2152,132,86,1701,1159,1636,3388,1034,2204,1527,90,2533,914,2652,1075,1706,1307,243,1644,1959,2098,154,2156,1895,2467,1584,1963,2753,2214,139,147,450,1783,16,1605,2490,3440,1656,1725,3433,624,645,362,1990,436,1451,322,438,473,314,387,198,571,1932,1933,23,146,3278,2724,97
|
-0.5205619963614778,0.12481764303170995,1.129846507529864,0.15021822725387687,-0.46394015097449753,-2.9021986504963437,0.6132320530882964,-0.6646226489620753,-1.1202280506221005,1.7248659083694862,0.22576972351761432,-0.2973496050355208,-0.782559488471584,0.7523010836930542,3.266090717897094,-2.357998717266434,0.6366343901410989,0.8657956397936897,-2.0115427231268868,0.99924807807911,-0.05613225744942473,0.2756058236423961,0.8657956397936897,1.4855121512311098,-2.2399728259652774,-0.3523458255088766,-1.6862217513646123,5.00137826845172,-0.2973496050355208,-0.933530264018968,3.463771008364262,0.20069322429525754,-0.029937337355577215,-0.812431823101089,-0.5777501510624806,0.20069322429525754,0.2507402549882607,0.15021822725387687,-0.3523458255088766,0.2507402549882607,0.9106055997578559,2.3221030889708456,3.4487695757462786,-0.38004199286570056,4.465429303037878,-0.32478217017330907,2.141400980540596,2.6690160857083316,-0.13543039550688563,0.12481764303170995,-0.10887756899447036,-1.479725735965493,0.20069322429525754,-0.3523458255088766,-0.05613225744942473,2.635145909771866,-0.4921810762200194,0.2756058236423961,-0.5490844868874409,0.1755097373274426,-0.13543039550688563,0.04795069293778851,1.3623028978368232,-0.10887756899447036,-0.24287217557351562,-0.2973496050355208,1.9175959588678502,-0.32478217017330907,-0.21582458354418593,-0.46394015097449753,-0.08244526537605792,-0.24287217557351562,-0.6065606205962223,-0.3523458255088766,2.067668972449665,1.9930749898852833,0.7523010836930542,-0.16210499188174082,3.95501878428734,-0.08244526537605792,-0.46394015097449753,-3.845785240619678,-0.10887756899447036,-0.13543039550688563,-2.357998717266434,0.5424727361776948,0.5186994533961014,0.9550879611029554,-0.24287217557351562,0.7979543947770469,-0.0038593161671487642,1.0648954266698725,0.7979543947770469,0.7293444986172449,1.086622325488035,0.9106055997578559,1.6658789469386504,0.6132320530882964,-0.21582458354418593,-0.21582458354418593,3.699372205651011,2.0118055412307876,-1.088674970956618,-0.5777501510624806,2.515194930023786
| 3,447
|
Tetrapyrrole binding
| 8
| 16
| 2.796478
| 0.005166
|
P09601,Q9H7Z7,P30519,O00264,O43169,Q16850,Q6UW02,O15173
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
68,438,17,300,50,185,218,91
|
300,2681,91,50,463,68,909,17,992,185,218,1444,2497,771,438,2128
|
1.129846507529864,-0.5777501510624806,2.6010990317026987,3.266090717897094,0.7293444986172449,2.885003643625329,0.2756058236423961,3.94106406729976,0.22576972351761432,1.7444059316466967,1.5260458493085034,-0.0038593161671487642,-0.46394015097449753,0.39839338050516404,0.7979543947770469,-0.2973496050355208
| 3,447
|
Protein transporter activity
| 8
| 14
| 2.791603
| 0.005245
|
Q99595,Q9HD20,Q15388,P49755,Q9Y5J9,O14925,Q9NS69,O60830
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
32,104,139,399,279,240,19,57
|
240,57,446,714,399,914,678,139,1724,32,104,19,670,279
|
1.3830082140752036,3.0782810890943333,0.7523010836930542,0.42264946952153903,0.8657956397936897,0.2756058236423961,0.4708675653967537,2.067668972449665,-0.13543039550688563,3.5234451642020086,2.4456443351957327,3.856733849716352,0.4948313489884187,1.2577250368668513
| 3,447
|
Outer mitochondrial membrane protein complex
| 14
| 16
| 2.790666
| 0.00526
|
Q5XKP0,Q8IWA4,O96008,Q15388,O94826,Q6UXV4,Q9BUR5,Q9NS69,Q8N4H5,Q9NX63,Q9Y512,Q13505,Q9NVH1,O75431
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
328,451,714,139,446,663,667,19,84,414,613,151,710,249
|
249,446,714,2148,151,139,792,328,663,451,84,667,19,710,414,613
|
1.3206836082734048,0.7523010836930542,0.42264946952153903,-0.32478217017330907,1.9554475850393123,2.067668972449665,0.3740380583531353,1.0430911699330094,0.4948313489884187,0.7523010836930542,2.7027116151259793,0.4948313489884187,3.856733849716352,0.44680723292840124,0.8432660990380526,0.5661520429850156
| 3,447
|
Circulatory system process
| 20
| 77
| 2.789716
| 0.005275
|
P02786,P08183,P30825,P16615,Q9UIQ6,O60568,Q07954,Q12959,P0DP25,Q9Y5X3,P42892,P53985,Q9HB40,P42785,O75844,P09601,Q9NZ08,Q16625,P33527,P41440
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,131,138,390,23,404,154,285,407,428,37,47,48,55,64,68,198,351,348,119
|
1192,1684,575,404,2447,1342,64,3384,1625,2016,3009,614,1,2018,1628,551,836,3096,131,715,68,407,2393,783,985,3264,1154,986,390,2022,2687,750,3121,675,2884,138,348,119,2460,1572,55,37,3210,3100,1203,47,1353,1162,2155,2935,1576,1304,509,3416,842,3190,814,154,3396,285,2101,1080,1257,1209,759,351,450,1974,3213,2554,1787,2811,48,584,198,23,428
|
0.09930691761130685,-0.13543039550688563,0.5897382077871124,0.8432660990380526,-0.46394015097449753,0.02210297651221063,2.9500592169623037,-1.479725735965493,-0.10887756899447036,-0.2700467318806754,-0.782559488471584,0.5424727361776948,6.163282040099825,-0.2700467318806754,-0.10887756899447036,0.6132320530882964,0.32502601874310844,-0.8726553252537929,2.141400980540596,0.42264946952153903,2.885003643625329,0.8432660990380526,-0.43583767226307185,0.3740380583531353,0.22576972351761432,-1.088674970956618,0.12481764303170995,0.22576972351761432,0.888241909646759,-0.2700467318806754,-0.5777501510624806,0.39839338050516404,-0.9030103721202933,0.4708675653967537,-0.6938776197516214,2.067668972449665,0.977207970824741,2.3221030889708456,-0.46394015097449753,-0.08244526537605792,3.109952884310997,3.4487695757462786,-0.9950727563608438,-0.8726553252537929,0.09930691761130685,3.31222899499851,0.02210297651221063,0.12481764303170995,-0.32478217017330907,-0.7232842213033084,-0.08244526537605792,0.04795069293778851,0.6599460191541926,-1.6862217513646123,0.32502601874310844,-0.9642170344811924,0.3495825824320858,1.9175959588678502,-1.5476919401678764,1.2153931970579401,-0.2973496050355208,0.1755097373274426,0.07368496760344917,0.09930691761130685,0.39839338050516404,0.977207970824741,0.7523010836930542,-0.24287217557351562,-0.9950727563608438,-0.4921810762200194,-0.16210499188174082,-0.6355175563328855,3.31222899499851,0.5897382077871124,1.6658789469386504,3.699372205651011,0.8206525871716301
| 3,447
|
Transmembrane transport
| 86
| 221
| 2.787394
| 0.005313
|
P21796,P78417,P45880,O75746,Q9UHG3,Q9HC21,Q8WTV0,Q9NS69,P23786,O75947,O95202,Q99595,Q70HW3,P06576,O75964,P53985,O60830,Q9BSK2,Q8IXU6,P05023,Q8NEW0,Q5T1Q4,Q4KMQ2,Q9Y6M7,Q9NVV0,O75844,Q9H2D1,O14745,O43865,Q8NE86,Q9UJZ1,P36542,P50416,Q9HD20,Q9Y619,P51790,Q7L0J3,Q9H2V7,P41440,O43772,Q99623,Q9UDW1,P46934,Q8N4V1,Q15629,P08183,P08195,Q06787,P30825,Q15388,Q9UGP8,O60831,Q07820,Q96ES6,P38435,Q9UBX3,Q8NE01,Q8WWC4,O43615,Q13423,Q8TB61,Q99797,O14925,P04062,P13073,Q9BPX6,Q6KCM7,P56385,Q12959,P27105,P00403,Q16625,P33527,P31751,O95831,P16615,P49755,P0DP25,Q6P4Q7,P20674,O94826,P08574,Q14728,Q8IWX8,Q02978,P98194
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
3,509,7,506,11,540,16,19,21,522,523,32,35,38,44,47,57,58,59,551,61,62,580,585,584,64,66,575,74,604,612,592,594,104,107,619,112,114,119,118,645,124,126,127,128,131,630,634,138,139,670,653,678,171,174,199,196,210,212,215,223,232,240,245,250,278,274,270,285,306,338,351,348,375,373,390,399,407,423,417,446,463,499,500,496,495
|
1564,2008,3301,2678,1111,575,240,212,1287,118,1147,74,1685,57,653,688,3148,1518,1065,864,804,506,64,1688,522,44,446,523,1876,2734,373,714,338,2391,245,551,836,905,1690,3179,38,1691,1630,3096,1344,2632,131,630,463,1745,407,1069,2254,783,985,2633,748,907,250,390,2022,2687,1696,750,417,1947,3048,3121,3,675,21,988,1241,306,3320,785,3051,2884,138,375,1158,3184,348,2782,592,1473,174,1634,3349,119,3287,7,126,808,753,2933,399,594,990,619,2646,2531,3307,47,1353,1477,1416,1162,1756,270,2697,2533,1818,914,1576,509,495,1578,2095,842,496,1959,1580,3344,634,678,1709,2538,285,215,1763,1764,2043,499,817,3362,139,128,759,2658,2474,351,1167,580,62,274,2848,698,1974,423,1489,1215,35,112,821,2801,500,59,127,196,604,61,885,1782,223,1439,1090,16,210,2764,171,1007,1845,703,1787,1661,3389,1223,32,645,232,278,1053,1500,58,1327,854,3089,3313,928,66,114,2811,1853,799,968,540,104,2374,2504,19,929,2562,584,1453,199,124,670,2915,11,2065,860,612,899,776,2869,1562,976,107,3430,585
|
-0.08244526537605792,-0.2700467318806754,-1.1519610734492034,-0.5777501510624806,0.15021822725387687,0.5897382077871124,1.3830082140752036,1.5663180339062512,0.04795069293778851,2.3221030889708456,0.12481764303170995,2.7861995187828263,-0.13543039550688563,3.0782810890943333,0.4948313489884187,0.44680723292840124,-0.933530264018968,-0.05613225744942473,0.1755097373274426,0.3003674196569163,0.3495825824320858,0.6599460191541926,2.9500592169623037,-0.13543039550688563,0.6366343901410989,3.342812226590406,0.7523010836930542,0.6366343901410989,-0.21582458354418593,-0.6065606205962223,0.9106055997578559,0.42264946952153903,0.99924807807911,-0.43583767226307185,1.341528204791294,0.6132320530882964,0.32502601874310844,0.2756058236423961,-0.13543039550688563,-0.9642170344811924,3.4186660677529486,-0.13543039550688563,-0.10887756899447036,-0.8726553252537929,0.02210297651221063,-0.5490844868874409,2.141400980540596,0.5186994533961014,0.7293444986172449,-0.16210499188174082,0.8432660990380526,0.1755097373274426,-0.38004199286570056,0.3740380583531353,0.22576972351761432,-0.5490844868874409,0.39839338050516404,0.2756058236423961,1.3206836082734048,0.888241909646759,-0.2700467318806754,-0.5777501510624806,-0.13543039550688563,0.39839338050516404,0.8206525871716301,-0.24287217557351562,-0.812431823101089,-0.9030103721202933,5.00137826845172,0.4708675653967537,3.7713507579645107,0.22576972351761432,0.07368496760344917,1.1082724828312556,-1.1838763713319127,0.3740380583531353,-0.812431823101089,-0.6938776197516214,2.067668972449665,0.9106055997578559,0.12481764303170995,-0.9642170344811924,0.977207970824741,-0.6355175563328855,0.5661520429850156,-0.029937337355577215,1.783305087665594,-0.10887756899447036,-1.280739952990378,2.3221030889708456,-1.1202280506221005,4.465429303037878,2.1779507009923273,0.3495825824320858,0.39839338050516404,-0.7232842213033084,0.8657956397936897,0.5661520429850156,0.22576972351761432,0.5424727361776948,-0.5490844868874409,-0.4921810762200194,-1.1519610734492034,3.31222899499851,0.02210297651221063,-0.029937337355577215,-0.0038593161671487642,0.12481764303170995,-0.16210499188174082,1.2577250368668513,-0.5777501510624806,-0.4921810762200194,-0.18890262528843013,0.2756058236423961,-0.08244526537605792,0.6599460191541926,0.6831677294955423,-0.08244526537605792,-0.2973496050355208,0.32502601874310844,0.6831677294955423,-0.24287217557351562,-0.08244526537605792,-1.2482633580866476,0.5186994533961014,0.4708675653967537,-0.13543039550688563,-0.4921810762200194,1.2153931970579401,1.5462143927925178,-0.16210499188174082,-0.16210499188174082,-0.2700467318806754,0.6831677294955423,0.3495825824320858,-1.3462719949496813,2.067668972449665,2.1597019144209066,0.39839338050516404,-0.5490844868874409,-0.46394015097449753,0.977207970824741,0.12481764303170995,0.5897382077871124,2.966223445923369,1.2577250368668513,-0.6646226489620753,0.44680723292840124,-0.24287217557351562,0.8206525871716301,-0.029937337355577215,0.09930691761130685,3.478739117626629,2.3753388484773885,0.3495825824320858,-0.6355175563328855,0.6831677294955423,2.9984338403792496,2.1779507009923273,1.6658789469386504,0.5661520429850156,2.9823482482966575,0.3003674196569163,-0.16210499188174082,1.4855121512311098,-0.0038593161671487642,0.1755097373274426,3.95501878428734,1.5863572419499614,-0.6065606205962223,1.8026650560757604,0.22576972351761432,-0.18890262528843013,0.44680723292840124,-0.16210499188174082,-0.10887756899447036,-1.479725735965493,0.09930691761130685,3.5234451642020086,0.5186994533961014,1.444713076909665,1.2577250368668513,0.20069322429525754,-0.029937337355577215,3.0782810890943333,0.04795069293778851,0.32502601874310844,-0.8424631282046733,-1.1519610734492034,0.2756058236423961,2.9176116047506313,2.3753388484773885,-0.6355175563328855,-0.18890262528843013,0.3740380583531353,0.2507402549882607,0.6366343901410989,2.4456443351957327,-0.4078721182203763,-0.46394015097449753,3.856733849716352,0.2756058236423961,-0.4921810762200194,0.5897382077871124,-0.0038593161671487642,1.6658789469386504,2.232387500674451,0.4948313489884187,-0.6938776197516214,4.051916232933154,-0.2700467318806754,0.32502601874310844,0.5661520429850156,0.3003674196569163,0.39839338050516404,-0.6646226489620753,-0.05613225744942473,0.2507402549882607,2.4281394545085906,-2.0865995574724328,0.5897382077871124
| 3,447
|
Cation transmembrane transport
| 44
| 123
| 2.783666
| 0.005375
|
P13073,P21796,P78417,P08195,P30825,P16615,Q9HC21,Q9BPX6,Q6KCM7,P56385,O75947,O95202,Q12959,P0DP25,Q70HW3,P06576,Q6P4Q7,Q96ES6,P20674,O75964,P27105,P05023,Q8NEW0,Q4KMQ2,Q9Y6M7,Q9NVV0,O14745,Q8NE86,Q8WWC4,Q9UJZ1,O43772,Q13423,P00403,P08574,P36542,Q9HD20,Q9Y619,P51790,Q8IWX8,P98194,Q99623,Q9UDW1,P46934,Q8N4V1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
250,3,509,630,138,390,540,278,274,270,522,523,285,407,35,38,423,171,417,44,306,551,61,580,585,584,575,604,210,612,118,215,338,463,592,104,107,619,500,495,645,124,126,127
|
2678,1111,575,1287,118,1685,688,1518,1065,804,522,44,523,2734,338,2391,551,836,905,1690,3179,38,1691,1630,1344,2632,630,463,407,1069,2633,748,250,390,2022,2687,1696,750,417,1947,3048,3121,3,675,988,1241,306,3320,3051,2884,138,1158,2782,592,1473,1634,3287,126,808,753,2933,990,619,1353,1477,1416,1162,1756,270,1818,914,1576,509,495,1578,2095,1580,634,1709,2538,285,215,1764,2043,3362,759,580,274,423,1489,35,500,127,604,61,210,2764,171,1845,703,1787,3389,645,278,1500,854,928,2811,1853,799,540,104,929,584,124,2915,2065,612,899,2869,976,107,585
|
-0.5777501510624806,0.15021822725387687,0.5897382077871124,0.04795069293778851,2.3221030889708456,-0.13543039550688563,0.44680723292840124,-0.05613225744942473,0.1755097373274426,0.3495825824320858,0.6366343901410989,3.342812226590406,0.6366343901410989,-0.6065606205962223,0.99924807807911,-0.43583767226307185,0.6132320530882964,0.32502601874310844,0.2756058236423961,-0.13543039550688563,-0.9642170344811924,3.4186660677529486,-0.13543039550688563,-0.10887756899447036,0.02210297651221063,-0.5490844868874409,0.5186994533961014,0.7293444986172449,0.8432660990380526,0.1755097373274426,-0.5490844868874409,0.39839338050516404,1.3206836082734048,0.888241909646759,-0.2700467318806754,-0.5777501510624806,-0.13543039550688563,0.39839338050516404,0.8206525871716301,-0.24287217557351562,-0.812431823101089,-0.9030103721202933,5.00137826845172,0.4708675653967537,0.22576972351761432,0.07368496760344917,1.1082724828312556,-1.1838763713319127,-0.812431823101089,-0.6938776197516214,2.067668972449665,0.12481764303170995,-0.6355175563328855,0.5661520429850156,-0.029937337355577215,-0.10887756899447036,-1.1202280506221005,2.1779507009923273,0.3495825824320858,0.39839338050516404,-0.7232842213033084,0.22576972351761432,0.5424727361776948,0.02210297651221063,-0.029937337355577215,-0.0038593161671487642,0.12481764303170995,-0.16210499188174082,1.2577250368668513,-0.18890262528843013,0.2756058236423961,-0.08244526537605792,0.6599460191541926,0.6831677294955423,-0.08244526537605792,-0.2973496050355208,-0.08244526537605792,0.5186994533961014,-0.13543039550688563,-0.4921810762200194,1.2153931970579401,1.5462143927925178,-0.16210499188174082,-0.2700467318806754,-1.3462719949496813,0.39839338050516404,0.5897382077871124,1.2577250368668513,0.8206525871716301,-0.029937337355577215,3.478739117626629,0.6831677294955423,2.1779507009923273,0.5661520429850156,2.9823482482966575,1.5863572419499614,-0.6065606205962223,1.8026650560757604,-0.18890262528843013,0.44680723292840124,-0.16210499188174082,-1.479725735965493,0.5186994533961014,1.2577250368668513,-0.029937337355577215,0.32502601874310844,0.2756058236423961,-0.6355175563328855,-0.18890262528843013,0.3740380583531353,0.6366343901410989,2.4456443351957327,0.2756058236423961,0.5897382077871124,2.232387500674451,-0.6938776197516214,-0.2700467318806754,0.5661520429850156,0.3003674196569163,-0.6646226489620753,0.2507402549882607,2.4281394545085906,0.5897382077871124
| 3,447
|
Cytochrome complex
| 7
| 16
| 2.778724
| 0.005457
|
P14406,P13073,P20674,O14949,P00403,Q9UDW1,P09669
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,250,417,108,338,124,406
|
1111,108,338,463,406,1069,250,0,1116,942,417,806,1158,753,124,831
|
0.15021822725387687,2.4105871078712475,0.99924807807911,0.7293444986172449,0.8432660990380526,0.1755097373274426,1.3206836082734048,6.3352481246556165,0.15021822725387687,0.2507402549882607,0.8206525871716301,0.3495825824320858,0.12481764303170995,0.39839338050516404,2.232387500674451,0.3495825824320858
| 3,447
|
Sphingolipid biosynthetic process
| 6
| 19
| 2.777331
| 0.005481
|
O95470,Q06136,Q96G23,P04062,P27544,Q16880
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,109,148,245,60,253
|
685,1113,33,245,3097,1885,60,2894,109,2161,2102,253,1430,793,148,277,1670,972,1557
|
0.44680723292840124,0.15021822725387687,3.5085760309399507,1.341528204791294,-0.8726553252537929,-0.21582458354418593,2.9823482482966575,-0.6938776197516214,2.3929870039150383,-0.32478217017330907,-0.2973496050355208,1.3206836082734048,-0.0038593161671487642,0.3740380583531353,1.9930749898852833,1.2577250368668513,-0.10887756899447036,0.2507402549882607,-0.05613225744942473
| 3,447
|
Inner mitochondrial membrane organization
| 13
| 19
| 2.772978
| 0.005555
|
Q5XKP0,O94826,Q6UXV4,Q9Y5J9,Q8WWC4,Q9BUR5,Q9NX63,Q9P0J0,Q13505,Q9Y512,O95202,O75431,Q9H3K2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
328,446,663,279,210,667,414,184,151,613,523,249,490
|
833,249,446,523,2148,151,792,1430,328,663,210,667,490,710,414,184,976,613,279
|
0.32502601874310844,1.3206836082734048,0.7523010836930542,0.6366343901410989,-0.32478217017330907,1.9554475850393123,0.3740380583531353,-0.0038593161671487642,1.0430911699330094,0.4948313489884187,1.5863572419499614,0.4948313489884187,0.706300299890814,0.44680723292840124,0.8432660990380526,1.7638855180459252,0.2507402549882607,0.5661520429850156,1.2577250368668513
| 3,447
|
Alzheimers disease
| 20
| 65
| 2.772113
| 0.005569
|
P14406,P13073,P49327,P16615,Q07954,O75947,P0DP25,O43676,P09669,P06576,P20674,P27361,P00403,P08574,O95168,O75306,O14949,P21912,Q9Y6M9,Q9UDW1
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
0,250,132,390,154,522,407,29,406,38,417,465,338,463,477,105,108,236,257,124
|
1143,2439,1111,108,29,1872,1518,105,2578,674,1687,522,477,1149,2015,713,338,2392,905,38,1630,463,406,407,1069,250,0,2197,1116,942,390,2739,2080,417,236,806,988,1241,465,3079,3153,2400,1158,592,2784,753,2933,132,3331,721,1575,2095,154,2156,2272,2043,1164,562,2216,1268,2497,2907,124,2915,257
|
0.12481764303170995,-0.46394015097449753,0.15021822725387687,2.4105871078712475,3.5973040673963035,-0.21582458354418593,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,0.4708675653967537,-0.13543039550688563,0.6366343901410989,0.706300299890814,0.12481764303170995,-0.2700467318806754,0.42264946952153903,0.99924807807911,-0.43583767226307185,0.2756058236423961,3.4186660677529486,-0.10887756899447036,0.7293444986172449,0.8432660990380526,0.8432660990380526,0.1755097373274426,1.3206836082734048,6.3352481246556165,-0.3523458255088766,0.15021822725387687,0.2507402549882607,0.888241909646759,-0.6065606205962223,-0.2973496050355208,0.8206525871716301,1.4036446740202682,0.3495825824320858,0.22576972351761432,0.07368496760344917,0.7293444986172449,-0.8424631282046733,-0.933530264018968,-0.43583767226307185,0.12481764303170995,0.5661520429850156,-0.6355175563328855,0.39839338050516404,-0.7232842213033084,2.141400980540596,-1.2159763235501515,0.42264946952153903,-0.08244526537605792,-0.2973496050355208,1.9175959588678502,-0.32478217017330907,-0.38004199286570056,-0.2700467318806754,0.12481764303170995,0.6132320530882964,-0.3523458255088766,0.07368496760344917,-0.46394015097449753,-0.6938776197516214,2.232387500674451,-0.6938776197516214,1.3206836082734048
| 3,447
|
Ion transmembrane transport
| 58
| 160
| 2.769645
| 0.005612
|
P13073,P21796,P78417,P08183,P08195,P45880,O75746,P30825,Q9UHG3,P16615,Q9HC21,Q9BPX6,Q6KCM7,P56385,O75947,O95202,Q12959,P0DP25,Q70HW3,P06576,Q6P4Q7,Q96ES6,P20674,O75964,P53985,P27105,P05023,Q8NEW0,Q4KMQ2,Q9Y6M7,Q9NVV0,O75844,Q9H2D1,Q9UBX3,O14745,O43865,Q8NE86,Q8WWC4,Q9UJZ1,O43772,Q13423,P00403,P08574,Q8TB61,P36542,P33527,Q9HD20,Q9Y619,Q14728,P51790,Q8IWX8,Q02978,P98194,P41440,Q99623,Q9UDW1,P46934,Q8N4V1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
250,3,509,131,630,7,506,138,11,390,540,278,274,270,522,523,285,407,35,38,423,171,417,44,47,306,551,61,580,585,584,64,66,199,575,74,604,210,612,118,215,338,463,223,592,348,104,107,499,619,500,496,495,119,645,124,126,127
|
3301,2678,1111,575,1287,118,1147,74,1685,653,688,3148,1518,1065,804,506,64,1688,522,44,523,1876,2734,338,2391,551,836,905,1690,3179,38,1691,1630,1344,2632,131,630,463,1745,407,1069,2633,748,907,250,390,2022,2687,1696,750,417,1947,3048,3121,3,675,988,1241,306,3320,3051,2884,138,1158,348,2782,592,1473,1634,119,3287,7,126,808,753,2933,990,619,2646,3307,47,1353,1477,1416,1162,1756,270,1818,914,1576,509,495,1578,2095,496,1580,634,1709,2538,285,215,1763,1764,2043,499,817,3362,759,2474,580,274,2848,423,1489,35,821,500,127,604,61,223,1090,210,2764,171,1845,703,1787,3389,645,278,1053,1500,1327,854,928,66,2811,1853,799,540,104,2374,929,584,199,124,2915,11,2065,860,612,899,776,2869,1562,976,107,3430,585
|
-1.1519610734492034,-0.5777501510624806,0.15021822725387687,0.5897382077871124,0.04795069293778851,2.3221030889708456,0.12481764303170995,2.7861995187828263,-0.13543039550688563,0.4948313489884187,0.44680723292840124,-0.933530264018968,-0.05613225744942473,0.1755097373274426,0.3495825824320858,0.6599460191541926,2.9500592169623037,-0.13543039550688563,0.6366343901410989,3.342812226590406,0.6366343901410989,-0.21582458354418593,-0.6065606205962223,0.99924807807911,-0.43583767226307185,0.6132320530882964,0.32502601874310844,0.2756058236423961,-0.13543039550688563,-0.9642170344811924,3.4186660677529486,-0.13543039550688563,-0.10887756899447036,0.02210297651221063,-0.5490844868874409,2.141400980540596,0.5186994533961014,0.7293444986172449,-0.16210499188174082,0.8432660990380526,0.1755097373274426,-0.5490844868874409,0.39839338050516404,0.2756058236423961,1.3206836082734048,0.888241909646759,-0.2700467318806754,-0.5777501510624806,-0.13543039550688563,0.39839338050516404,0.8206525871716301,-0.24287217557351562,-0.812431823101089,-0.9030103721202933,5.00137826845172,0.4708675653967537,0.22576972351761432,0.07368496760344917,1.1082724828312556,-1.1838763713319127,-0.812431823101089,-0.6938776197516214,2.067668972449665,0.12481764303170995,0.977207970824741,-0.6355175563328855,0.5661520429850156,-0.029937337355577215,-0.10887756899447036,2.3221030889708456,-1.1202280506221005,4.465429303037878,2.1779507009923273,0.3495825824320858,0.39839338050516404,-0.7232842213033084,0.22576972351761432,0.5424727361776948,-0.5490844868874409,-1.1519610734492034,3.31222899499851,0.02210297651221063,-0.029937337355577215,-0.0038593161671487642,0.12481764303170995,-0.16210499188174082,1.2577250368668513,-0.18890262528843013,0.2756058236423961,-0.08244526537605792,0.6599460191541926,0.6831677294955423,-0.08244526537605792,-0.2973496050355208,0.6831677294955423,-0.08244526537605792,0.5186994533961014,-0.13543039550688563,-0.4921810762200194,1.2153931970579401,1.5462143927925178,-0.16210499188174082,-0.16210499188174082,-0.2700467318806754,0.6831677294955423,0.3495825824320858,-1.3462719949496813,0.39839338050516404,-0.46394015097449753,0.5897382077871124,1.2577250368668513,-0.6646226489620753,0.8206525871716301,-0.029937337355577215,3.478739117626629,0.3495825824320858,0.6831677294955423,2.1779507009923273,0.5661520429850156,2.9823482482966575,1.4855121512311098,0.1755097373274426,1.5863572419499614,-0.6065606205962223,1.8026650560757604,-0.18890262528843013,0.44680723292840124,-0.16210499188174082,-1.479725735965493,0.5186994533961014,1.2577250368668513,0.20069322429525754,-0.029937337355577215,0.04795069293778851,0.32502601874310844,0.2756058236423961,2.9176116047506313,-0.6355175563328855,-0.18890262528843013,0.3740380583531353,0.6366343901410989,2.4456443351957327,-0.4078721182203763,0.2756058236423961,0.5897382077871124,1.6658789469386504,2.232387500674451,-0.6938776197516214,4.051916232933154,-0.2700467318806754,0.32502601874310844,0.5661520429850156,0.3003674196569163,0.39839338050516404,-0.6646226489620753,-0.05613225744942473,0.2507402549882607,2.4281394545085906,-2.0865995574724328,0.5897382077871124
| 3,447
|
Protein processing
| 10
| 48
| 2.761728
| 0.00575
|
Q2T9J0,O75844,O75503,P42892,Q10713,P00558,Q99797,Q92896,P67812,Q15392
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
192,64,220,37,102,39,232,238,241,147
|
1870,2823,804,220,64,266,2966,39,3207,1691,2079,2022,2687,2739,3047,1411,2784,37,1949,1575,871,241,102,1897,1164,1361,147,2474,192,470,1902,1371,852,1268,238,888,1845,1052,232,3296,707,773,2233,1330,1862,612,2245,976
|
-0.21582458354418593,-0.6646226489620753,0.3495825824320858,1.4855121512311098,2.9500592169623037,1.278782566805988,-0.7528442383323635,3.3732566413381613,-0.9950727563608438,-0.13543039550688563,-0.2973496050355208,-0.2700467318806754,-0.5777501510624806,-0.6065606205962223,-0.812431823101089,-0.0038593161671487642,-0.6355175563328855,3.4487695757462786,-0.24287217557351562,-0.08244526537605792,0.3003674196569163,1.3830082140752036,2.46310203854336,-0.21582458354418593,0.12481764303170995,0.02210297651221063,1.9930749898852833,-0.46394015097449753,1.685602847740683,0.7293444986172449,-0.21582458354418593,0.02210297651221063,0.32502601874310844,0.07368496760344917,1.4036446740202682,0.3003674196569163,-0.18890262528843013,0.20069322429525754,1.444713076909665,-1.1202280506221005,0.44680723292840124,0.39839338050516404,-0.3523458255088766,0.04795069293778851,-0.18890262528843013,0.5661520429850156,-0.3523458255088766,0.2507402549882607
| 3,447
|
Cholesterol metabolism with bloch and kandutschrussell pathways
| 8
| 24
| 2.761093
| 0.005761
|
Q9UBM7,P49327,O76062,P37268,P48449,Q15392,Q15800,Q16850
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
129,132,165,8,42,147,52,185
|
2570,2309,227,165,1196,1027,3184,947,8,42,132,400,3234,3310,726,727,1767,3107,147,1593,52,185,2175,129
|
-0.5205619963614778,-0.4078721182203763,1.4651460309893183,1.8412078293006888,0.09930691761130685,0.20069322429525754,-0.9642170344811924,0.2507402549882607,4.308266492154955,3.35805169719967,2.141400980540596,0.8657956397936897,-1.0260995428738104,-1.1519610734492034,0.42264946952153903,0.42264946952153903,-0.16210499188174082,-0.8726553252537929,1.9930749898852833,-0.08244526537605792,3.250640313041074,1.7444059316466967,-0.32478217017330907,2.1597019144209066
| 3,447
|
Organic acid transmembrane transport
| 22
| 32
| 2.760106
| 0.005778
|
P31751,P08183,Q15758,P08195,O75746,P30825,Q9H9B4,P23786,P11166,O60831,P28288,P53985,Q15041,Q96NB2,Q9H2D1,Q9UBX3,P33527,P50416,Q9Y619,Q02978,P41440,O43772
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
375,131,759,630,506,138,799,21,783,653,785,47,817,703,66,199,348,594,107,496,119,118
|
118,653,506,1688,1876,3179,131,630,783,21,785,138,375,3184,348,119,594,3307,47,496,817,759,2848,1090,703,1053,66,1853,799,199,860,107
|
2.3221030889708456,0.4948313489884187,0.6599460191541926,-0.13543039550688563,-0.21582458354418593,-0.9642170344811924,2.141400980540596,0.5186994533961014,0.3740380583531353,3.7713507579645107,0.3740380583531353,2.067668972449665,0.9106055997578559,-0.9642170344811924,0.977207970824741,2.3221030889708456,0.5661520429850156,-1.1519610734492034,3.31222899499851,0.6831677294955423,0.3495825824320858,0.39839338050516404,-0.6646226489620753,0.1755097373274426,0.44680723292840124,0.20069322429525754,2.9176116047506313,-0.18890262528843013,0.3740380583531353,1.6658789469386504,0.32502601874310844,2.4281394545085906
| 3,447
|
Proton transporting two sector atpase complex
| 11
| 22
| 2.759281
| 0.005793
|
P06576,Q96IX5,Q93050,O75964,Q15904,Q9Y5K8,Q8N511,P56385,P56378,O75947,Q9Y487
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
38,606,202,44,600,546,53,270,441,522,159
|
522,44,38,1947,3048,988,1241,592,1473,1634,2933,1756,441,270,1818,600,53,202,606,2065,159,546
|
0.6366343901410989,3.342812226590406,3.4186660677529486,-0.24287217557351562,-0.812431823101089,0.22576972351761432,0.07368496760344917,0.5661520429850156,-0.029937337355577215,-0.10887756899447036,-0.7232842213033084,-0.16210499188174082,0.7751708030625595,1.2577250368668513,-0.18890262528843013,0.5661520429850156,3.204073554666814,1.6460928822167984,0.5661520429850156,-0.2700467318806754,1.87951707419191,0.6366343901410989
| 3,447
|
Vascular process in circulatory system
| 10
| 33
| 2.749488
| 0.005969
|
P02786,P33527,P08183,P42892,P30825,P53985,Q9HB40,P41440,Q16625,Q07954
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
1,348,131,37,138,47,48,119,351,154
|
1684,575,404,2447,1625,1,2018,3096,131,783,985,750,675,138,348,119,37,3210,3100,47,1162,2935,842,3190,814,154,2101,1209,759,351,1974,2554,48
|
-0.13543039550688563,0.5897382077871124,0.8432660990380526,-0.46394015097449753,-0.10887756899447036,6.163282040099825,-0.2700467318806754,-0.8726553252537929,2.141400980540596,0.3740380583531353,0.22576972351761432,0.39839338050516404,0.4708675653967537,2.067668972449665,0.977207970824741,2.3221030889708456,3.4487695757462786,-0.9950727563608438,-0.8726553252537929,3.31222899499851,0.12481764303170995,-0.7232842213033084,0.32502601874310844,-0.9642170344811924,0.3495825824320858,1.9175959588678502,-0.2973496050355208,0.09930691761130685,0.39839338050516404,0.977207970824741,-0.24287217557351562,-0.4921810762200194,3.31222899499851
| 3,447
|
Steroid biosynthesis
| 10
| 25
| 2.741123
| 0.006123
|
Q9UBM7,Q9H3P7,O75845,O76062,P37268,P48449,Q15392,Q15800,Q16850,Q53GQ0
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
129,322,227,165,8,42,147,52,185,290
|
227,165,3009,1027,8,42,400,841,3234,2161,3310,727,1767,3107,147,1593,52,185,290,1542,2762,890,322,129,973
|
1.4651460309893183,1.8412078293006888,-0.782559488471584,0.20069322429525754,4.308266492154955,3.35805169719967,0.8657956397936897,0.32502601874310844,-1.0260995428738104,-0.32478217017330907,-1.1519610734492034,0.42264946952153903,-0.16210499188174082,-0.8726553252537929,1.9930749898852833,-0.08244526537605792,3.250640313041074,1.7444059316466967,1.1941177625102746,-0.05613225744942473,-0.6065606205962223,0.3003674196569163,1.0648954266698725,2.1597019144209066,0.2507402549882607
| 3,447
|
Abnormality of the mitochondrion
| 16
| 91
| 2.740944
| 0.006126
|
Q70HW3,Q96CU9,Q9UBX3,Q86Y39,O75306,P21912,P03886,Q16836,P23786,P49748,O43772,P35637,Q9P0J0,Q9Y6M9,Q9Y2R0,O43676
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,4,199,230,105,236,15,176,21,86,118,150,184,257,27,29
|
2439,2009,1192,1111,29,1872,3359,118,1518,105,2578,1687,980,865,2015,713,338,15,2391,1879,2019,2584,1880,3435,748,250,2827,2080,417,236,3303,21,2636,3079,3014,2400,150,3016,2525,376,1699,2692,86,3331,1202,721,695,2532,2091,1637,2463,597,1578,1422,3195,760,2216,176,3108,1167,728,412,997,2279,3161,35,764,1130,2800,230,1439,1320,4,966,644,2420,2907,1500,1272,1014,473,583,2622,184,2433,199,27,712,976,2919,257
|
-0.46394015097449753,-0.2700467318806754,0.09930691761130685,0.15021822725387687,3.5973040673963035,-0.21582458354418593,-1.3462719949496813,2.3221030889708456,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,-0.13543039550688563,0.22576972351761432,0.3003674196569163,-0.2700467318806754,0.42264946952153903,0.99924807807911,3.9689451889376715,-0.43583767226307185,-0.21582458354418593,-0.2700467318806754,-0.5205619963614778,-0.21582458354418593,-2.8583845407454613,0.39839338050516404,1.3206836082734048,-0.6646226489620753,-0.2973496050355208,0.8206525871716301,1.4036446740202682,-1.1519610734492034,3.7713507579645107,-0.5490844868874409,-0.8424631282046733,-0.782559488471584,-0.43583767226307185,1.9554475850393123,-0.782559488471584,-0.4921810762200194,0.9106055997578559,-0.13543039550688563,-0.5777501510624806,2.6690160857083316,-1.2159763235501515,0.09930691761130685,0.42264946952153903,0.44680723292840124,-0.4921810762200194,-0.2973496050355208,-0.10887756899447036,-0.46394015097449753,0.5661520429850156,-0.08244526537605792,-0.0038593161671487642,-0.9642170344811924,0.39839338050516404,-0.3523458255088766,1.783305087665594,-0.8726553252537929,0.12481764303170995,0.42264946952153903,0.8432660990380526,0.22576972351761432,-0.38004199286570056,-0.933530264018968,3.478739117626629,0.39839338050516404,0.15021822725387687,-0.6355175563328855,1.444713076909665,-0.0038593161671487642,0.04795069293778851,4.904690951021535,0.2507402549882607,0.5186994533961014,-0.43583767226307185,-0.6938776197516214,-0.029937337355577215,0.07368496760344917,0.22576972351761432,0.7293444986172449,0.5897382077871124,-0.5205619963614778,1.7638855180459252,-0.43583767226307185,1.6658789469386504,3.6558165597384233,0.44680723292840124,0.2507402549882607,-0.6938776197516214,1.3206836082734048
| 3,447
|
Basal part of cell
| 17
| 51
| 2.739963
| 0.006145
|
Q9Y6M7,P02786,P33527,P57105,P08195,Q6P4Q7,Q07954,P30825,P53985,P35613,P42785,P41440,O75955,P05023,Q14168,Q12959,Q9BY67
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
585,1,348,228,630,423,154,138,47,591,55,119,550,551,409,285,515
|
2438,2008,1145,2074,550,1874,2194,3432,1,981,551,836,1691,630,1520,783,2255,2197,1346,986,1240,750,675,1407,138,2523,348,1243,591,119,55,47,1416,1162,228,1303,1304,814,154,2538,285,1582,1535,409,2042,759,423,1323,2808,515,585
|
-0.46394015097449753,-0.2700467318806754,0.12481764303170995,-0.2973496050355208,0.6132320530882964,-0.21582458354418593,-0.3523458255088766,-2.357998717266434,6.163282040099825,0.22576972351761432,0.6132320530882964,0.32502601874310844,-0.13543039550688563,0.5186994533961014,-0.05613225744942473,0.3740380583531353,-0.38004199286570056,-0.3523458255088766,0.02210297651221063,0.22576972351761432,0.07368496760344917,0.39839338050516404,0.4708675653967537,-0.0038593161671487642,2.067668972449665,-0.4921810762200194,0.977207970824741,0.07368496760344917,0.5661520429850156,2.3221030889708456,3.109952884310997,3.31222899499851,-0.0038593161671487642,0.12481764303170995,1.4651460309893183,0.04795069293778851,0.04795069293778851,0.3495825824320858,1.9175959588678502,-0.4921810762200194,1.2153931970579401,-0.08244526537605792,-0.05613225744942473,0.8432660990380526,-0.2700467318806754,0.39839338050516404,0.8206525871716301,0.04795069293778851,-0.6355175563328855,0.6599460191541926,0.5897382077871124
| 3,447
|
Inorganic ion transmembrane transport
| 41
| 115
| 2.738927
| 0.006164
|
P13073,P21796,P78417,P08195,P16615,Q9UHG3,Q9BPX6,Q6KCM7,P56385,O75947,O95202,Q12959,P0DP25,P06576,Q6P4Q7,Q96ES6,P20674,O75964,P27105,P05023,Q4KMQ2,Q9Y6M7,Q9NVV0,Q9UBX3,O14745,Q8NE86,Q8WWC4,Q9UJZ1,Q13423,P00403,P08574,P36542,Q9HD20,P51790,Q8IWX8,Q02978,P98194,Q99623,Q9UDW1,P46934,Q8N4V1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
250,3,509,630,390,11,278,274,270,522,523,285,407,38,423,171,417,44,306,551,580,585,584,199,575,604,210,612,215,338,463,592,104,619,500,496,495,645,124,126,127
|
2678,1111,575,1287,1685,688,1518,1065,804,522,44,523,2734,338,2391,551,836,1690,3179,38,1691,1344,2632,630,463,407,1069,2633,748,250,390,2022,2687,1696,750,417,1947,3048,3121,3,675,988,1241,306,3320,3051,2884,1158,2782,592,1473,1634,3287,126,808,753,2933,990,619,2646,1353,1477,1416,1162,1756,270,1818,914,1576,509,495,1578,2095,496,1580,634,1709,2538,285,215,1764,2043,580,274,423,1489,500,127,604,210,2764,171,1845,1787,3389,645,278,1500,854,928,2811,1853,104,929,584,199,124,2915,11,2065,612,899,2869,976,585
|
-0.5777501510624806,0.15021822725387687,0.5897382077871124,0.04795069293778851,-0.13543039550688563,0.44680723292840124,-0.05613225744942473,0.1755097373274426,0.3495825824320858,0.6366343901410989,3.342812226590406,0.6366343901410989,-0.6065606205962223,0.99924807807911,-0.43583767226307185,0.6132320530882964,0.32502601874310844,-0.13543039550688563,-0.9642170344811924,3.4186660677529486,-0.13543039550688563,0.02210297651221063,-0.5490844868874409,0.5186994533961014,0.7293444986172449,0.8432660990380526,0.1755097373274426,-0.5490844868874409,0.39839338050516404,1.3206836082734048,0.888241909646759,-0.2700467318806754,-0.5777501510624806,-0.13543039550688563,0.39839338050516404,0.8206525871716301,-0.24287217557351562,-0.812431823101089,-0.9030103721202933,5.00137826845172,0.4708675653967537,0.22576972351761432,0.07368496760344917,1.1082724828312556,-1.1838763713319127,-0.812431823101089,-0.6938776197516214,0.12481764303170995,-0.6355175563328855,0.5661520429850156,-0.029937337355577215,-0.10887756899447036,-1.1202280506221005,2.1779507009923273,0.3495825824320858,0.39839338050516404,-0.7232842213033084,0.22576972351761432,0.5424727361776948,-0.5490844868874409,0.02210297651221063,-0.029937337355577215,-0.0038593161671487642,0.12481764303170995,-0.16210499188174082,1.2577250368668513,-0.18890262528843013,0.2756058236423961,-0.08244526537605792,0.6599460191541926,0.6831677294955423,-0.08244526537605792,-0.2973496050355208,0.6831677294955423,-0.08244526537605792,0.5186994533961014,-0.13543039550688563,-0.4921810762200194,1.2153931970579401,1.5462143927925178,-0.16210499188174082,-0.2700467318806754,0.5897382077871124,1.2577250368668513,0.8206525871716301,-0.029937337355577215,0.6831677294955423,2.1779507009923273,0.5661520429850156,1.5863572419499614,-0.6065606205962223,1.8026650560757604,-0.18890262528843013,-0.16210499188174082,-1.479725735965493,0.5186994533961014,1.2577250368668513,-0.029937337355577215,0.32502601874310844,0.2756058236423961,-0.6355175563328855,-0.18890262528843013,2.4456443351957327,0.2756058236423961,0.5897382077871124,1.6658789469386504,2.232387500674451,-0.6938776197516214,4.051916232933154,-0.2700467318806754,0.5661520429850156,0.3003674196569163,-0.6646226489620753,0.2507402549882607,0.5897382077871124
| 3,447
|
Mental deterioration
| 29
| 102
| 2.730634
| 0.006321
|
P03886,P50897,P35637,Q9Y487,O95470,P61916,Q9BQE5,P04350,P27544,P22626,O15118,Q5XKP0,Q14108,P17900,P43243,P00403,Q9NQZ5,P07602,O75503,Q10713,P31483,P20700,O75306,P21912,Q03164,O76024,Q6Y7W6,P54802,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
15,144,150,159,33,420,43,173,60,317,67,328,70,448,466,338,216,339,220,102,358,479,105,236,237,235,369,368,245
|
1192,67,1396,935,833,2073,2964,105,220,235,476,2016,33,714,338,15,2391,245,3206,173,905,2313,339,3379,3228,2735,782,2584,1746,1402,3011,448,1403,479,236,751,317,2636,60,2400,358,150,1473,1634,1699,3287,466,2889,144,3186,1203,2091,368,723,2463,420,2033,1759,237,3157,1708,3252,634,2156,102,557,1422,2102,70,1256,3195,1971,328,3161,1649,369,794,1435,764,665,1603,885,1267,1605,888,1788,2420,3389,3029,2907,43,1272,583,216,1276,3092,571,897,1279,3145,1060,159
|
0.09930691761130685,2.885003643625329,-0.0038593161671487642,0.2507402549882607,0.32502601874310844,-0.2973496050355208,-0.7528442383323635,2.4281394545085906,1.4855121512311098,1.4036446740202682,0.706300299890814,-0.2700467318806754,3.5085760309399507,0.42264946952153903,0.99924807807911,3.9689451889376715,-0.43583767226307185,1.341528204791294,-0.9950727563608438,1.783305087665594,0.2756058236423961,-0.4078721182203763,0.99924807807911,-1.4460567516253717,-1.0260995428738104,-0.6065606205962223,0.3740380583531353,-0.5205619963614778,-0.16210499188174082,-0.0038593161671487642,-0.782559488471584,0.7523010836930542,-0.0038593161671487642,0.706300299890814,1.4036446740202682,0.39839338050516404,1.0648954266698725,-0.5490844868874409,2.9823482482966575,-0.43583767226307185,0.9550879611029554,1.9554475850393123,-0.029937337355577215,-0.10887756899447036,-0.13543039550688563,-1.1202280506221005,0.7293444986172449,-0.6938776197516214,2.0304811478621976,-0.9642170344811924,0.09930691761130685,-0.2973496050355208,0.9328873923979636,0.42264946952153903,-0.46394015097449753,0.8206525871716301,-0.2700467318806754,-0.16210499188174082,1.4036446740202682,-0.933530264018968,-0.13543039550688563,-1.0572995486724805,0.5186994533961014,-0.32478217017330907,2.46310203854336,0.6132320530882964,-0.0038593161671487642,-0.2973496050355208,2.8522335346715137,0.07368496760344917,-0.9642170344811924,-0.24287217557351562,1.0430911699330094,-0.933530264018968,-0.10887756899447036,0.9328873923979636,0.3740380583531353,-0.0038593161671487642,0.39839338050516404,0.4948313489884187,-0.08244526537605792,0.3003674196569163,0.07368496760344917,-0.08244526537605792,0.3003674196569163,-0.16210499188174082,-0.43583767226307185,-1.479725735965493,-0.782559488471584,-0.6938776197516214,3.35805169719967,0.07368496760344917,0.5897382077871124,1.5462143927925178,0.07368496760344917,-0.8424631282046733,0.6132320530882964,0.3003674196569163,0.07368496760344917,-0.9030103721202933,0.20069322429525754,1.87951707419191
| 3,447
|
Basolateral plasma membrane
| 16
| 45
| 2.729913
| 0.006335
|
Q9Y6M7,P02786,P33527,P57105,P08195,Q6P4Q7,Q07954,P30825,P53985,P35613,P41440,O75955,P05023,Q14168,Q12959,Q9BY67
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
585,1,348,228,630,423,154,138,47,591,119,550,551,409,285,515
|
2008,1145,550,1874,2194,3432,1,981,551,836,1691,630,1520,783,2255,2197,1346,986,1240,750,675,1407,138,2523,348,1243,591,119,47,1416,1162,228,1303,1304,814,154,2538,285,1535,409,2042,423,2808,515,585
|
-0.2700467318806754,0.12481764303170995,0.6132320530882964,-0.21582458354418593,-0.3523458255088766,-2.357998717266434,6.163282040099825,0.22576972351761432,0.6132320530882964,0.32502601874310844,-0.13543039550688563,0.5186994533961014,-0.05613225744942473,0.3740380583531353,-0.38004199286570056,-0.3523458255088766,0.02210297651221063,0.22576972351761432,0.07368496760344917,0.39839338050516404,0.4708675653967537,-0.0038593161671487642,2.067668972449665,-0.4921810762200194,0.977207970824741,0.07368496760344917,0.5661520429850156,2.3221030889708456,3.31222899499851,-0.0038593161671487642,0.12481764303170995,1.4651460309893183,0.04795069293778851,0.04795069293778851,0.3495825824320858,1.9175959588678502,-0.4921810762200194,1.2153931970579401,-0.05613225744942473,0.8432660990380526,-0.2700467318806754,0.8206525871716301,-0.6355175563328855,0.6599460191541926,0.5897382077871124
| 3,447
|
Cellular respiration
| 30
| 103
| 2.728499
| 0.006362
|
P14406,P13073,O75746,P03886,Q9NZ45,Q6KCM7,P56385,O75947,O43676,P43304,O75874,P06576,P20674,O75964,P48735,Q16718,Q15070,Q9BSK2,Q9UJZ1,Q13423,P00403,P08574,Q9H3K2,O95168,O75306,O14949,P21912,P04062,Q9Y6M9,Q9UDW1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,250,506,15,545,274,270,522,29,283,293,38,417,44,175,562,181,58,612,215,338,463,490,477,105,108,236,245,257,124
|
2439,1111,108,29,1872,935,978,1518,105,1065,2578,2965,674,1687,506,293,522,44,477,1149,2015,713,338,15,2391,245,2018,939,38,2453,1879,463,2019,2584,1069,1880,250,2827,0,2256,2197,1116,942,2080,417,2634,236,806,988,1241,807,3079,3051,2586,2400,1158,2260,2524,592,1412,2525,2589,3126,1754,283,753,2933,175,3331,3082,721,2532,2463,1756,270,2935,1819,1252,215,181,1209,760,562,2216,274,2546,2283,1439,2118,3389,2497,2556,2367,58,490,1853,545,1556,2433,124,860,612,257
|
-0.46394015097449753,0.15021822725387687,2.4105871078712475,3.5973040673963035,-0.21582458354418593,0.2507402549882607,0.22576972351761432,-0.05613225744942473,2.4281394545085906,0.1755097373274426,-0.5205619963614778,-0.7528442383323635,0.4708675653967537,-0.13543039550688563,0.6599460191541926,1.1727685570073243,0.6366343901410989,3.342812226590406,0.706300299890814,0.12481764303170995,-0.2700467318806754,0.42264946952153903,0.99924807807911,3.9689451889376715,-0.43583767226307185,1.341528204791294,-0.2700467318806754,0.2507402549882607,3.4186660677529486,-0.46394015097449753,-0.21582458354418593,0.7293444986172449,-0.2700467318806754,-0.5205619963614778,0.1755097373274426,-0.21582458354418593,1.3206836082734048,-0.6646226489620753,6.3352481246556165,-0.38004199286570056,-0.3523458255088766,0.15021822725387687,0.2507402549882607,-0.2973496050355208,0.8206525871716301,-0.5490844868874409,1.4036446740202682,0.3495825824320858,0.22576972351761432,0.07368496760344917,0.3495825824320858,-0.8424631282046733,-0.812431823101089,-0.5205619963614778,-0.43583767226307185,0.12481764303170995,-0.38004199286570056,-0.4921810762200194,0.5661520429850156,-0.0038593161671487642,-0.4921810762200194,-0.5205619963614778,-0.9030103721202933,-0.16210499188174082,1.2153931970579401,0.39839338050516404,-0.7232842213033084,1.783305087665594,-1.2159763235501515,-0.8424631282046733,0.42264946952153903,-0.4921810762200194,-0.46394015097449753,-0.16210499188174082,1.2577250368668513,-0.7232842213033084,-0.18890262528843013,0.07368496760344917,1.5462143927925178,1.7638855180459252,0.09930691761130685,0.39839338050516404,0.6132320530882964,-0.3523458255088766,1.2577250368668513,-0.4921810762200194,-0.38004199286570056,-0.0038593161671487642,-0.2973496050355208,-1.479725735965493,-0.46394015097449753,-0.4921810762200194,-0.4078721182203763,3.0782810890943333,0.706300299890814,-0.18890262528843013,0.6366343901410989,-0.05613225744942473,-0.43583767226307185,2.232387500674451,0.32502601874310844,0.5661520429850156,1.3206836082734048
| 3,447
|
Endoplasmic reticulum organization
| 19
| 44
| 2.72685
| 0.006394
|
Q15629,Q12907,Q15042,Q96A33,Q8N766,Q9NPA0,Q9P2W9,Q9P0I2,A0FGR8,Q15041,O95197,Q9NVV0,Q9NQC3,P46379,Q8N5M9,Q15363,Q8NHH9,O15027,Q8N4V1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,876,919,537,795,542,152,426,673,817,180,584,207,92,360,233,766,744,127
|
673,1192,2187,744,1803,1396,1741,2192,180,1875,92,1119,1120,1529,2032,914,1077,876,2039,995,817,919,233,128,1648,1217,127,360,795,2486,766,537,1447,1920,1732,1995,1733,542,207,584,1670,426,1557,152
|
0.4708675653967537,0.09930691761130685,-0.3523458255088766,0.39839338050516404,-0.18890262528843013,-0.0038593161671487642,-0.16210499188174082,-0.3523458255088766,1.7638855180459252,-0.21582458354418593,2.6010990317026987,0.15021822725387687,0.15021822725387687,-0.05613225744942473,-0.2700467318806754,0.2756058236423961,0.1755097373274426,0.3003674196569163,-0.2700467318806754,0.22576972351761432,0.3495825824320858,0.2756058236423961,1.4242127921315773,2.1597019144209066,-0.10887756899447036,0.09930691761130685,2.1779507009923273,0.9550879611029554,0.3740380583531353,-0.46394015097449753,0.39839338050516404,0.6366343901410989,-0.0038593161671487642,-0.21582458354418593,-0.13543039550688563,-0.24287217557351562,-0.13543039550688563,0.6366343901410989,1.6063324809623214,0.5897382077871124,-0.10887756899447036,0.8206525871716301,-0.05613225744942473,1.9365499879520078
| 3,447
|
Mitochondrial membrane organization
| 21
| 44
| 2.724133
| 0.006447
|
P45880,Q6UXV4,Q9Y5J9,Q9BUR5,Q9NS69,Q9NX63,Q13505,O95202,P0DP25,O14737,Q9P0J0,Q15070,Q9UII2,Q5XKP0,Q8IWA4,O94826,Q8WWC4,Q9Y512,Q9H3K2,O95140,O75431
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
7,663,279,667,19,414,151,523,407,301,184,181,458,328,451,446,210,613,490,476,249
|
2872,301,833,249,446,476,523,1238,1690,1026,2314,407,748,3051,3015,2929,2148,2745,7,3210,2531,151,181,2474,792,1167,1430,328,663,451,2114,2048,210,667,490,19,710,414,184,458,831,976,613,279
|
-0.6938776197516214,1.129846507529864,0.32502601874310844,1.3206836082734048,0.7523010836930542,0.706300299890814,0.6366343901410989,0.07368496760344917,-0.13543039550688563,0.20069322429525754,-0.4078721182203763,0.8432660990380526,0.39839338050516404,-0.812431823101089,-0.782559488471584,-0.7232842213033084,-0.32478217017330907,-0.6065606205962223,4.465429303037878,-0.9950727563608438,-0.4921810762200194,1.9554475850393123,1.7638855180459252,-0.46394015097449753,0.3740380583531353,0.12481764303170995,-0.0038593161671487642,1.0430911699330094,0.4948313489884187,0.7523010836930542,-0.2973496050355208,-0.2700467318806754,1.5863572419499614,0.4948313489884187,0.706300299890814,3.856733849716352,0.44680723292840124,0.8432660990380526,1.7638855180459252,0.7523010836930542,0.3495825824320858,0.2507402549882607,0.5661520429850156,1.2577250368668513
| 3,447
|
Cholesterol biosynthesis
| 7
| 18
| 2.721799
| 0.006493
|
Q9UBM7,O76062,P37268,P48449,Q15392,Q15800,Q16850
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
129,165,8,42,147,52,185
|
227,165,1027,8,42,400,3234,3310,726,727,1767,3107,147,1593,52,185,2175,129
|
1.4651460309893183,1.8412078293006888,0.20069322429525754,4.308266492154955,3.35805169719967,0.8657956397936897,-1.0260995428738104,-1.1519610734492034,0.42264946952153903,0.42264946952153903,-0.16210499188174082,-0.8726553252537929,1.9930749898852833,-0.08244526537605792,3.250640313041074,1.7444059316466967,-0.32478217017330907,2.1597019144209066
| 3,447
|
Rnd1 gtpase cycle
| 6
| 15
| 2.702928
| 0.006873
|
P38159,P02786,P51648,O75976,Q15058,O43396
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
161,1,136,266,83,461
|
461,266,1,986,717,1409,161,136,1757,2042,83,502,1666,648,1737
|
0.7293444986172449,1.278782566805988,6.163282040099825,0.22576972351761432,0.42264946952153903,-0.0038593161671487642,1.8603914432017374,2.104641317835198,-0.16210499188174082,-0.2700467318806754,2.7027116151259793,0.6831677294955423,-0.10887756899447036,0.5186994533961014,-0.13543039550688563
| 3,447
|
Ventricular arrhythmia
| 10
| 37
| 2.702456
| 0.006883
|
P42892,O75306,P21912,P03886,O43772,P23786,P49748,P36551,P0DP25,P00403
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
37,105,236,15,118,21,86,429,407,338
|
118,105,2581,338,835,15,2391,1628,3228,715,407,2393,748,1154,986,1240,236,21,429,2973,3017,37,86,1351,467,2091,1353,1764,1080,764,1003,823,1320,824,2420,2497,1662
|
2.3221030889708456,2.4281394545085906,-0.5205619963614778,0.99924807807911,0.32502601874310844,3.9689451889376715,-0.43583767226307185,-0.10887756899447036,-1.0260995428738104,0.42264946952153903,0.8432660990380526,-0.43583767226307185,0.39839338050516404,0.12481764303170995,0.22576972351761432,0.07368496760344917,1.4036446740202682,3.7713507579645107,0.7979543947770469,-0.7528442383323635,-0.782559488471584,3.4487695757462786,2.6690160857083316,0.02210297651221063,0.7293444986172449,-0.2973496050355208,0.02210297651221063,-0.16210499188174082,0.1755097373274426,0.39839338050516404,0.22576972351761432,0.3495825824320858,0.04795069293778851,0.3495825824320858,-0.43583767226307185,-0.46394015097449753,-0.10887756899447036
| 3,447
|
Cis golgi network
| 10
| 18
| 2.702147
| 0.006889
|
Q9UNK9,P24390,O95249,Q08379,O00461,P49755,P98194,Q14789,O43731,Q8TBA6
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
427,36,440,299,46,399,495,599,188,320
|
46,1513,188,440,36,1032,399,495,299,599,879,2709,320,1545,1493,702,427,1109
|
3.31222899499851,-0.05613225744942473,1.7248659083694862,0.7751708030625595,3.463771008364262,0.20069322429525754,0.8657956397936897,0.6831677294955423,1.1513450009278545,0.5661520429850156,0.3003674196569163,-0.5777501510624806,1.0648954266698725,-0.05613225744942473,-0.029937337355577215,0.44680723292840124,0.8206525871716301,0.1755097373274426
| 3,447
|
Rnd2 gtpase cycle
| 6
| 17
| 2.696568
| 0.007006
|
P38159,P02786,P51648,O43396,Q15058,Q07065
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
161,1,136,461,83,442
|
461,1,717,161,136,442,1960,2938,1535,83,1131,502,2231,1666,1460,1335,1737
|
0.7293444986172449,6.163282040099825,0.42264946952153903,1.8603914432017374,2.104641317835198,0.7751708030625595,-0.24287217557351562,-0.7232842213033084,-0.05613225744942473,2.7027116151259793,0.15021822725387687,0.6831677294955423,-0.3523458255088766,-0.10887756899447036,-0.0038593161671487642,0.04795069293778851,-0.13543039550688563
| 3,447
|
Tclin
| 17
| 98
| 2.69402
| 0.00706
|
O43924,Q9BUF5,Q86Y39,P07437,O75306,Q13885,P04350,P03886,P38435,Q7L0J3,P48735,P00374,Q9P0J0,P49721,P27338,O43676,Q99720
|
Drugs and Diseases
|
Pharos IDG Category
|
pharos_protein_category
|
5,197,230,200,105,76,173,15,174,112,175,51,184,22,217,29,63
|
2439,1111,29,1872,5,2447,1518,105,2578,674,1687,477,1149,2015,713,51,3205,1689,2194,614,15,2391,3282,173,397,551,836,1877,3179,1945,200,3096,1344,2079,2583,407,2393,3180,985,1693,1567,838,2880,1027,2737,2080,478,2397,751,2926,1406,3122,3099,2636,217,694,3079,1408,2257,717,2147,869,174,1572,175,22,3331,2787,721,1353,1416,1162,556,3416,1248,2838,2894,1038,994,2101,2601,76,2342,562,2216,2986,112,230,2228,63,1272,197,355,2622,184,2720,1335,257
|
-0.46394015097449753,0.15021822725387687,3.5973040673963035,-0.21582458354418593,4.8435868415993255,-0.46394015097449753,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,0.4708675653967537,-0.13543039550688563,0.706300299890814,0.12481764303170995,-0.2700467318806754,0.42264946952153903,3.266090717897094,-0.9950727563608438,-0.13543039550688563,-0.3523458255088766,0.5424727361776948,3.9689451889376715,-0.43583767226307185,-1.1202280506221005,1.783305087665594,0.8657956397936897,0.6132320530882964,0.32502601874310844,-0.21582458354418593,-0.9642170344811924,-0.24287217557351562,1.6460928822167984,-0.8726553252537929,0.02210297651221063,-0.2973496050355208,-0.5205619963614778,0.8432660990380526,-0.43583767226307185,-0.9642170344811924,0.22576972351761432,-0.13543039550688563,-0.08244526537605792,0.32502601874310844,-0.6938776197516214,0.20069322429525754,-0.6065606205962223,-0.2973496050355208,0.706300299890814,-0.43583767226307185,0.39839338050516404,-0.7232842213033084,-0.0038593161671487642,-0.9030103721202933,-0.8726553252537929,-0.5490844868874409,1.5260458493085034,0.44680723292840124,-0.8424631282046733,-0.0038593161671487642,-0.38004199286570056,0.42264946952153903,-0.32478217017330907,0.3003674196569163,1.783305087665594,-0.08244526537605792,1.783305087665594,3.699372205651011,-1.2159763235501515,-0.6355175563328855,0.42264946952153903,0.02210297651221063,-0.0038593161671487642,0.12481764303170995,0.6132320530882964,-1.6862217513646123,0.07368496760344917,-0.6646226489620753,-0.6938776197516214,0.20069322429525754,0.22576972351761432,-0.2973496050355208,-0.5205619963614778,2.769586772818807,-0.4078721182203763,0.6132320530882964,-0.3523458255088766,-0.7528442383323635,2.3753388484773885,1.444713076909665,-0.3523458255088766,2.966223445923369,0.07368496760344917,1.6658789469386504,0.977207970824741,-0.5205619963614778,1.7638855180459252,-0.5777501510624806,0.04795069293778851,1.3206836082734048
| 3,447
|
Establishment of protein localization to membrane
| 24
| 89
| 2.693343
| 0.007074
|
Q15629,P31751,Q96A33,Q9Y5J9,Q9NS69,Q4J6C6,Q15907,Q9Y3D6,P0DP25,Q9P0I2,O14737,P27105,Q9P0J0,Q15070,O15118,O94826,Q8WWC4,P43307,P46379,O60725,Q9HD20,P98194,Q9H4A6,Q8N4V1
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,375,537,279,19,412,411,153,407,426,301,306,184,181,67,446,210,82,92,226,104,495,516,127
|
2438,2872,1337,301,744,67,1803,1396,1741,226,2824,3045,446,1196,2194,836,1026,837,3119,407,306,3015,2322,375,2929,2201,948,2459,82,92,2326,1119,754,1300,1638,789,2697,2651,2533,2032,914,3334,495,2095,1078,2538,1582,1535,995,817,919,181,128,600,411,412,1430,1217,2801,2359,3138,127,795,1724,210,537,1788,1661,1732,516,896,104,2374,542,19,2375,426,184,670,1932,2915,3002,1616,1106,831,153,1562,613,279
|
-0.46394015097449753,-0.6938776197516214,0.02210297651221063,1.129846507529864,0.39839338050516404,2.885003643625329,-0.18890262528843013,-0.0038593161671487642,-0.16210499188174082,1.4651460309893183,-0.6646226489620753,-0.812431823101089,0.7523010836930542,0.09930691761130685,-0.3523458255088766,0.32502601874310844,0.20069322429525754,0.32502601874310844,-0.9030103721202933,0.8432660990380526,1.1082724828312556,-0.782559488471584,-0.4078721182203763,0.9106055997578559,-0.7232842213033084,-0.3523458255088766,0.2507402549882607,-0.46394015097449753,2.7027116151259793,2.6010990317026987,-0.4078721182203763,0.15021822725387687,0.39839338050516404,0.04795069293778851,-0.10887756899447036,0.3740380583531353,-0.5777501510624806,-0.5490844868874409,-0.4921810762200194,-0.2700467318806754,0.2756058236423961,-1.2159763235501515,0.6831677294955423,-0.2973496050355208,0.1755097373274426,-0.4921810762200194,-0.08244526537605792,-0.05613225744942473,0.22576972351761432,0.3495825824320858,0.2756058236423961,1.7638855180459252,2.1597019144209066,0.5661520429850156,0.8432660990380526,0.8432660990380526,-0.0038593161671487642,0.09930691761130685,-0.6355175563328855,-0.4078721182203763,-0.9030103721202933,2.1779507009923273,0.3740380583531353,-0.13543039550688563,1.5863572419499614,0.6366343901410989,-0.16210499188174082,-0.10887756899447036,-0.13543039550688563,0.6599460191541926,0.3003674196569163,2.4456443351957327,-0.4078721182203763,0.6366343901410989,3.856733849716352,-0.4078721182203763,0.8206525871716301,1.7638855180459252,0.4948313489884187,-0.21582458354418593,-0.6938776197516214,-0.7528442383323635,-0.08244526537605792,0.1755097373274426,0.3495825824320858,1.9365499879520078,-0.05613225744942473,0.5661520429850156,1.2577250368668513
| 3,447
|
Mitochondrial carrier domain superfamily [IPR023395]
| 10
| 24
| 2.683564
| 0.007284
|
Q9H2D1,Q70HW3,Q9UBX3,O75746,Q9Y619,Q9HC21,Q6KCM7,Q02978,O43772,Q9BSK2
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
66,35,199,506,107,540,274,496,118,58
|
118,1147,506,1690,748,907,3307,1578,496,274,698,35,821,1007,1053,58,66,1853,540,571,199,860,107,901
|
2.3221030889708456,0.12481764303170995,0.6599460191541926,-0.13543039550688563,0.39839338050516404,0.2756058236423961,-1.1519610734492034,-0.08244526537605792,0.6831677294955423,1.2577250368668513,0.44680723292840124,3.478739117626629,0.3495825824320858,0.22576972351761432,0.20069322429525754,3.0782810890943333,2.9176116047506313,-0.18890262528843013,0.6366343901410989,0.6132320530882964,1.6658789469386504,0.32502601874310844,2.4281394545085906,0.3003674196569163
| 3,447
|
SLC25 family of mitochondrial transporters
| 10
| 24
| 2.683564
| 0.007284
|
Q9H2D1,Q70HW3,Q9UBX3,O75746,Q9Y619,Q9HC21,Q6KCM7,Q02978,O43772,Q9BSK2
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
66,35,199,506,107,540,274,496,118,58
|
118,1147,506,1690,748,907,3307,1578,496,274,698,35,821,1007,1053,58,66,1853,540,571,199,860,107,901
|
2.3221030889708456,0.12481764303170995,0.6599460191541926,-0.13543039550688563,0.39839338050516404,0.2756058236423961,-1.1519610734492034,-0.08244526537605792,0.6831677294955423,1.2577250368668513,0.44680723292840124,3.478739117626629,0.3495825824320858,0.22576972351761432,0.20069322429525754,3.0782810890943333,2.9176116047506313,-0.18890262528843013,0.6366343901410989,0.6132320530882964,1.6658789469386504,0.32502601874310844,2.4281394545085906,0.3003674196569163
| 3,447
|
Mitochondrial substrate/solute carrier [IPR018108]
| 10
| 24
| 2.683564
| 0.007284
|
Q9H2D1,Q70HW3,Q9UBX3,O75746,Q9Y619,Q9HC21,Q6KCM7,Q02978,O43772,Q9BSK2
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
66,35,199,506,107,540,274,496,118,58
|
118,1147,506,1690,748,907,3307,1578,496,274,698,35,821,1007,1053,58,66,1853,540,571,199,860,107,901
|
2.3221030889708456,0.12481764303170995,0.6599460191541926,-0.13543039550688563,0.39839338050516404,0.2756058236423961,-1.1519610734492034,-0.08244526537605792,0.6831677294955423,1.2577250368668513,0.44680723292840124,3.478739117626629,0.3495825824320858,0.22576972351761432,0.20069322429525754,3.0782810890943333,2.9176116047506313,-0.18890262528843013,0.6366343901410989,0.6132320530882964,1.6658789469386504,0.32502601874310844,2.4281394545085906,0.3003674196569163
| 3,447
|
Abnormal muscle fiber morphology
| 17
| 67
| 2.673931
| 0.007497
|
Q9H2D1,Q70HW3,O95831,P07196,P31483,P22626,O14979,P03886,Q9BPX6,O43676,P50402,P23786,P35637,P00403,P51114,P61978,Q99720
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,35,373,221,358,317,169,15,278,29,467,21,150,338,408,284,63
|
1111,169,29,2308,833,2075,980,373,714,338,835,15,2391,3391,905,2251,221,2777,782,748,2317,2883,317,21,2400,358,150,2084,466,467,990,408,3307,2532,2091,2463,284,1249,2703,1308,1764,2840,2792,1969,997,2109,35,764,2989,1130,1085,2168,3139,1439,823,2420,63,278,1662,1178,66,1182,1275,831,2435,976,1681
|
0.15021822725387687,1.8026650560757604,3.5973040673963035,-0.4078721182203763,0.32502601874310844,-0.2973496050355208,0.22576972351761432,0.9106055997578559,0.42264946952153903,0.99924807807911,0.32502601874310844,3.9689451889376715,-0.43583767226307185,-1.5136031541581185,0.2756058236423961,-0.38004199286570056,1.4855121512311098,-0.6355175563328855,0.3740380583531353,0.39839338050516404,-0.4078721182203763,-0.6938776197516214,1.0648954266698725,3.7713507579645107,-0.43583767226307185,0.9550879611029554,1.9554475850393123,-0.2973496050355208,0.7293444986172449,0.7293444986172449,0.22576972351761432,0.8432660990380526,-1.1519610734492034,-0.4921810762200194,-0.2973496050355208,-0.46394015097449753,1.2153931970579401,0.07368496760344917,-0.5777501510624806,0.04795069293778851,-0.16210499188174082,-0.6646226489620753,-0.6355175563328855,-0.24287217557351562,0.22576972351761432,-0.2973496050355208,3.478739117626629,0.39839338050516404,-0.7528442383323635,0.15021822725387687,0.1755097373274426,-0.32478217017330907,-0.9030103721202933,-0.0038593161671487642,0.3495825824320858,-0.43583767226307185,2.966223445923369,1.2577250368668513,-0.10887756899447036,0.12481764303170995,2.9176116047506313,0.12481764303170995,0.07368496760344917,0.3495825824320858,-0.43583767226307185,0.2507402549882607,-0.10887756899447036
| 3,447
|
Organelle subcompartment
| 129
| 376
| 2.666887
| 0.007656
|
P11717,P37268,Q5BJF2,Q96A33,Q16799,Q9NPA0,P30519,P46977,P04439,P07099,O95470,P24390,Q7Z2K6,Q9BQE5,P48449,O00461,Q9Y3A3,Q9Y282,Q15800,Q8N511,P27544,Q99720,O75844,Q9NVV0,Q96S52,P09601,Q15437,Q14108,O43865,Q96L58,Q86UL3,Q9BS26,Q15904,P43307,Q9P2E5,Q14789,P35613,O15260,Q8NBZ7,Q10713,Q6NUQ1,Q9HD20,Q9BT22,Q06136,Q969V3,P16435,Q96HY6,Q13190,Q86YN1,Q9NP80,Q8N4V1,Q15629,Q9UBM7,Q6NUM9,O94874,P51648,Q8N0U8,Q9Y2B2,Q9UGP8,Q9BUR5,Q15392,Q96G23,Q9P2W9,Q86XL3,O43852,O76062,Q8IV08,P38435,Q9BRR6,O95197,Q16850,O43731,Q96ED9,Q9NZ08,Q86UE4,Q9NQC3,Q9H3N1,Q8TB61,O60725,O75845,Q15363,O76024,P67812,Q9NZ01,P04062,Q13438,Q9NX62,Q9UNZ2,Q9Y5M8,Q9Y3B3,Q12959,Q53GQ0,Q08379,O00264,Q8TBA6,Q9C005,Q99640,Q96A57,Q9UBU6,Q70UQ0,Q13724,Q7Z3C6,Q8N5M9,Q96N66,Q99735,Q86Y07,Q9H1C4,P16615,P10321,P49755,Q7Z6M1,Q4J6C6,O60568,Q9P0I2,P51571,Q10472,Q9Y679,O95249,Q07065,Q96PC5,Q9BU23,Q6P179,P50402,Q92643,Q8IWX8,P98194,Q8NAT1,Q9Y5X1,Q9H4A6
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
507,8,10,537,531,542,17,527,524,31,33,36,40,43,42,46,573,49,52,53,60,63,64,584,582,68,579,70,74,607,602,608,600,82,610,599,591,587,94,102,621,104,625,109,113,615,643,635,121,122,127,128,129,134,628,136,140,671,670,667,147,148,152,156,160,165,170,174,183,180,185,188,193,198,195,207,211,223,226,227,233,235,241,244,245,252,263,264,280,282,285,290,299,300,320,321,330,329,336,353,349,359,360,361,362,370,385,390,398,399,413,412,404,426,419,421,439,440,442,455,456,450,467,488,500,495,513,519,516
|
673,2068,300,1192,1684,46,2820,1337,2570,3227,1565,2571,1144,1112,744,1624,587,685,1113,2629,1803,687,188,2385,2725,160,74,2309,1465,404,226,1063,2014,2074,2075,2143,1804,1397,1944,64,227,1688,235,165,628,3008,1400,3178,2192,866,180,440,1875,33,1626,2631,1196,904,3009,2194,245,524,982,1627,905,939,31,837,1198,906,68,1745,398,507,941,615,390,1882,944,3012,3121,1885,2883,36,1030,60,1471,784,3080,3124,1812,17,2884,2742,3184,1472,947,591,8,174,2025,1753,1572,82,2326,527,1573,42,1118,2786,1119,1120,754,1635,399,467,990,3154,419,809,136,810,1034,3375,3155,2977,2329,2463,1529,3103,2697,2593,2155,2651,871,2789,2032,1817,2206,2935,914,993,915,2698,3247,2267,3054,241,2336,495,1759,1077,2096,1249,1959,2702,2465,109,442,2938,299,815,421,816,102,1897,876,1822,285,2039,635,252,2340,1483,349,70,2656,2469,726,2043,727,1967,599,2753,1361,995,817,919,877,1767,3362,233,147,1166,579,128,1593,52,600,879,531,185,1428,412,290,10,1648,2707,1831,1832,1719,1433,2848,953,134,621,999,450,1974,820,793,1489,353,40,359,413,1084,195,602,1131,156,370,121,170,2359,500,665,140,958,1780,3138,127,53,1603,360,795,1838,513,94,1840,1046,2486,766,2761,2227,223,320,2363,1171,1439,852,1090,1091,1545,1092,1441,823,1493,1546,1494,488,1911,1548,113,680,537,329,2491,1381,193,148,1845,643,702,889,607,1846,361,455,582,1661,1223,330,3029,63,362,2992,2952,43,183,608,1447,625,798,456,705,667,1327,1179,1449,1011,3313,1099,321,1920,928,1100,385,1732,1182,211,516,708,2426,1506,2767,104,1733,122,542,207,2956,738,1927,584,1277,263,1670,244,198,972,426,1557,610,2507,152,2376,3069,129,336,1455,670,973,1140,3002,2815,2181,899,1141,1616,2960,264,49,777,671,1284,2378,573,1109,282,3280,2304,280,519,900,439
|
0.4708675653967537,-0.2973496050355208,1.129846507529864,0.09930691761130685,-0.13543039550688563,3.31222899499851,-0.6646226489620753,0.02210297651221063,-0.5205619963614778,-1.0260995428738104,-0.08244526537605792,-0.5205619963614778,0.12481764303170995,0.15021822725387687,0.39839338050516404,-0.10887756899447036,0.5661520429850156,0.44680723292840124,0.15021822725387687,-0.5490844868874409,-0.18890262528843013,0.44680723292840124,1.7248659083694862,-0.43583767226307185,-0.6065606205962223,1.8603914432017374,2.7861995187828263,-0.4078721182203763,-0.029937337355577215,0.8432660990380526,1.4651460309893183,0.1755097373274426,-0.2700467318806754,-0.2973496050355208,-0.2973496050355208,-0.32478217017330907,-0.18890262528843013,-0.0038593161671487642,-0.24287217557351562,2.9500592169623037,1.4651460309893183,-0.13543039550688563,1.4036446740202682,1.8412078293006888,0.5186994533961014,-0.782559488471584,-0.0038593161671487642,-0.9642170344811924,-0.3523458255088766,0.3003674196569163,1.7638855180459252,0.7751708030625595,-0.21582458354418593,3.5085760309399507,-0.10887756899447036,-0.5490844868874409,0.09930691761130685,0.2756058236423961,-0.782559488471584,-0.3523458255088766,1.341528204791294,0.6366343901410989,0.22576972351761432,-0.10887756899447036,0.2756058236423961,0.2507402549882607,3.5234451642020086,0.32502601874310844,0.09930691761130685,0.2756058236423961,2.885003643625329,-0.16210499188174082,0.8657956397936897,0.6599460191541926,0.2507402549882607,0.5424727361776948,0.888241909646759,-0.21582458354418593,0.2507402549882607,-0.782559488471584,-0.9030103721202933,-0.21582458354418593,-0.6938776197516214,3.463771008364262,0.20069322429525754,2.9823482482966575,-0.029937337355577215,0.3740380583531353,-0.8424631282046733,-0.9030103721202933,-0.18890262528843013,3.94106406729976,-0.6938776197516214,-0.6065606205962223,-0.9642170344811924,-0.029937337355577215,0.2507402549882607,0.5661520429850156,4.308266492154955,1.783305087665594,-0.2700467318806754,-0.16210499188174082,-0.08244526537605792,2.7027116151259793,-0.4078721182203763,0.6366343901410989,-0.08244526537605792,3.35805169719967,0.15021822725387687,-0.6355175563328855,0.15021822725387687,0.15021822725387687,0.39839338050516404,-0.10887756899447036,0.8657956397936897,0.7293444986172449,0.22576972351761432,-0.933530264018968,0.8206525871716301,0.3495825824320858,2.104641317835198,0.3495825824320858,0.20069322429525754,-1.4125933300875322,-0.933530264018968,-0.7528442383323635,-0.4078721182203763,-0.46394015097449753,-0.05613225744942473,-0.8726553252537929,-0.5777501510624806,-0.5205619963614778,-0.32478217017330907,-0.5490844868874409,0.3003674196569163,-0.6355175563328855,-0.2700467318806754,-0.18890262528843013,-0.3523458255088766,-0.7232842213033084,0.2756058236423961,0.22576972351761432,0.2756058236423961,-0.5777501510624806,-1.0572995486724805,-0.38004199286570056,-0.812431823101089,1.3830082140752036,-0.4078721182203763,0.6831677294955423,-0.16210499188174082,0.1755097373274426,-0.2973496050355208,0.07368496760344917,-0.24287217557351562,-0.5777501510624806,-0.46394015097449753,2.3929870039150383,0.7751708030625595,-0.7232842213033084,1.1513450009278545,0.3495825824320858,0.8206525871716301,0.3495825824320858,2.46310203854336,-0.21582458354418593,0.3003674196569163,-0.18890262528843013,1.2153931970579401,-0.2700467318806754,0.5186994533961014,1.3206836082734048,-0.4078721182203763,-0.029937337355577215,0.977207970824741,2.8522335346715137,-0.5490844868874409,-0.46394015097449753,0.42264946952153903,-0.2700467318806754,0.42264946952153903,-0.24287217557351562,0.5661520429850156,-0.6065606205962223,0.02210297651221063,0.22576972351761432,0.3495825824320858,0.2756058236423961,0.3003674196569163,-0.16210499188174082,-1.3462719949496813,1.4242127921315773,1.9930749898852833,0.12481764303170995,0.5897382077871124,2.1597019144209066,-0.08244526537605792,3.250640313041074,0.5661520429850156,0.3003674196569163,0.6366343901410989,1.7444059316466967,-0.0038593161671487642,0.8432660990380526,1.1941177625102746,4.147469617210321,-0.10887756899447036,-0.5777501510624806,-0.18890262528843013,-0.18890262528843013,-0.13543039550688563,-0.0038593161671487642,-0.6646226489620753,0.2507402549882607,2.1230475619495595,0.5424727361776948,0.22576972351761432,0.7523010836930542,-0.24287217557351562,0.3495825824320858,0.3740380583531353,-0.029937337355577215,0.977207970824741,3.3732566413381613,0.9550879611029554,0.8432660990380526,0.1755097373274426,1.6658789469386504,0.5661520429850156,0.15021822725387687,1.8985851161657519,0.9328873923979636,2.3042597288135043,1.8026650560757604,-0.4078721182203763,0.6831677294955423,0.4948313489884187,2.067668972449665,0.2507402549882607,-0.16210499188174082,-0.9030103721202933,2.1779507009923273,3.204073554666814,-0.08244526537605792,0.9550879611029554,0.3740380583531353,-0.18890262528843013,0.6599460191541926,2.5496928079060073,-0.18890262528843013,0.20069322429525754,-0.46394015097449753,0.39839338050516404,-0.6065606205962223,-0.3523458255088766,1.4855121512311098,1.0648954266698725,-0.4078721182203763,0.12481764303170995,-0.0038593161671487642,0.32502601874310844,0.1755097373274426,0.1755097373274426,-0.05613225744942473,0.1755097373274426,-0.0038593161671487642,0.3495825824320858,-0.029937337355577215,-0.05613225744942473,-0.029937337355577215,0.706300299890814,-0.21582458354418593,-0.05613225744942473,2.3753388484773885,0.4708675653967537,0.6366343901410989,1.0430911699330094,-0.46394015097449753,0.02210297651221063,1.685602847740683,1.9930749898852833,-0.18890262528843013,0.5186994533961014,0.44680723292840124,0.3003674196569163,0.5661520429850156,-0.18890262528843013,0.9550879611029554,0.7523010836930542,0.5897382077871124,-0.10887756899447036,0.09930691761130685,1.0430911699330094,-0.782559488471584,2.966223445923369,0.9550879611029554,-0.7528442383323635,-0.7232842213033084,3.35805169719967,1.7638855180459252,0.5661520429850156,-0.0038593161671487642,0.5424727361776948,0.3740380583531353,0.7523010836930542,0.44680723292840124,0.4948313489884187,0.04795069293778851,0.12481764303170995,-0.0038593161671487642,0.22576972351761432,-1.1519610734492034,0.1755097373274426,1.0648954266698725,-0.21582458354418593,0.2756058236423961,0.1755097373274426,0.9106055997578559,-0.13543039550688563,0.12481764303170995,1.5863572419499614,0.6599460191541926,0.44680723292840124,-0.43583767226307185,-0.029937337355577215,-0.6065606205962223,2.4456443351957327,-0.13543039550688563,2.3042597288135043,0.6366343901410989,1.6063324809623214,-0.7232842213033084,0.42264946952153903,-0.21582458354418593,0.5897382077871124,0.07368496760344917,1.2997685753674266,-0.10887756899447036,1.3623028978368232,1.6658789469386504,0.2507402549882607,0.8206525871716301,-0.05613225744942473,0.5661520429850156,-0.46394015097449753,1.9365499879520078,-0.4078721182203763,-0.812431823101089,2.1597019144209066,1.021208931090401,-0.0038593161671487642,0.4948313489884187,0.2507402549882607,0.15021822725387687,-0.7528442383323635,-0.6355175563328855,-0.32478217017330907,0.3003674196569163,0.15021822725387687,-0.08244526537605792,-0.7232842213033084,1.2997685753674266,3.2968848749628292,0.39839338050516404,0.4948313489884187,0.07368496760344917,-0.4078721182203763,0.6132320530882964,0.1755097373274426,1.236595433267566,-1.088674970956618,-0.38004199286570056,1.2577250368668513,0.6599460191541926,0.3003674196569163,0.7979543947770469
| 3,447
|
Cristae formation
| 12
| 19
| 2.662672
| 0.007752
|
P36542,Q5XKP0,P06576,Q6UXV4,O75964,Q9BUR5,Q9NX63,Q9Y512,P56385,Q13505,O75947,O75431
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
592,328,38,663,44,667,414,613,270,151,522,249
|
249,522,44,38,988,1241,592,2148,2933,1756,270,151,792,328,663,667,710,414,613
|
1.3206836082734048,0.6366343901410989,3.342812226590406,3.4186660677529486,0.22576972351761432,0.07368496760344917,0.5661520429850156,-0.32478217017330907,-0.7232842213033084,-0.16210499188174082,1.2577250368668513,1.9554475850393123,0.3740380583531353,1.0430911699330094,0.4948313489884187,0.4948313489884187,0.44680723292840124,0.8432660990380526,0.5661520429850156
| 3,447
|
Respiratory electron transport
| 17
| 53
| 2.66023
| 0.007809
|
P13073,Q86Y39,P20674,O95168,O75306,O14949,P03886,Q9H845,Q16718,P21912,Q9P0J0,P00403,P08574,Q9Y6M9,Q9UDW1,O43676,P09669
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
250,230,417,477,105,108,15,473,562,236,184,338,463,257,124,29,406
|
2439,1111,108,29,1872,935,1518,105,2578,674,1687,865,477,1149,2015,713,338,15,2391,463,406,1069,250,2827,1116,942,2080,417,236,806,3079,2400,1158,2525,1699,753,3331,721,1252,760,562,2216,230,2497,1097,1500,1272,473,583,2622,184,124,257
|
-0.46394015097449753,0.15021822725387687,2.4105871078712475,3.5973040673963035,-0.21582458354418593,0.2507402549882607,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,0.4708675653967537,-0.13543039550688563,0.3003674196569163,0.706300299890814,0.12481764303170995,-0.2700467318806754,0.42264946952153903,0.99924807807911,3.9689451889376715,-0.43583767226307185,0.7293444986172449,0.8432660990380526,0.1755097373274426,1.3206836082734048,-0.6646226489620753,0.15021822725387687,0.2507402549882607,-0.2973496050355208,0.8206525871716301,1.4036446740202682,0.3495825824320858,-0.8424631282046733,-0.43583767226307185,0.12481764303170995,-0.4921810762200194,-0.13543039550688563,0.39839338050516404,-1.2159763235501515,0.42264946952153903,0.07368496760344917,0.39839338050516404,0.6132320530882964,-0.3523458255088766,1.444713076909665,-0.46394015097449753,0.1755097373274426,-0.029937337355577215,0.07368496760344917,0.7293444986172449,0.5897382077871124,-0.5205619963614778,1.7638855180459252,2.232387500674451,1.3206836082734048
| 3,447
|
Metalloendopeptidase activity
| 6
| 14
| 2.659812
| 0.007818
|
O75844,P42892,Q10713,Q99797,Q9BYT8,Q92905
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,37,102,232,436,286
|
1516,804,64,2197,806,37,1476,102,470,286,1052,232,436,976
|
-0.05613225744942473,0.3495825824320858,2.9500592169623037,-0.3523458255088766,0.3495825824320858,3.4487695757462786,-0.029937337355577215,2.46310203854336,0.7293444986172449,1.2153931970579401,0.20069322429525754,1.444713076909665,0.7979543947770469,0.2507402549882607
| 3,447
|
Mitochondrial calcium ion transport
| 10
| 16
| 2.658161
| 0.007857
|
P21796,Q10713,P45880,Q8NE86,Q9BPX6,Q9H300,Q8WWC4,Q9UJZ1,Q99623,O95202
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
3,102,7,604,278,773,210,612,645,523
|
804,523,3,1244,7,102,604,210,1269,1052,645,278,773,612,776,976
|
0.3495825824320858,0.6366343901410989,5.00137826845172,0.07368496760344917,4.465429303037878,2.46310203854336,0.5661520429850156,1.5863572419499614,0.07368496760344917,0.20069322429525754,0.5186994533961014,1.2577250368668513,0.39839338050516404,0.5661520429850156,0.39839338050516404,0.2507402549882607
| 3,447
|
Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor
| 8
| 13
| 2.646936
| 0.008122
|
Q14914,Q9UBM7,P49327,O76062,Q15392,Q9NZ01,Q8N4Q0,Q9BY49
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
350,129,132,165,147,244,186,95
|
165,2325,132,2462,727,350,147,186,603,95,438,244,129
|
1.8412078293006888,-0.4078721182203763,2.141400980540596,-0.46394015097449753,0.42264946952153903,0.977207970824741,1.9930749898852833,1.7444059316466967,0.5661520429850156,2.515194930023786,0.7979543947770469,1.3623028978368232,2.1597019144209066
| 3,447
|
Symptomatic seizures
| 6
| 8
| 2.643814
| 0.008198
|
P40939,Q15813,P53985,Q16836,P00367,Q13423
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
376,260,47,176,80,215
|
80,375,376,47,215,260,176,1261
|
2.7194945196309765,0.9106055997578559,0.9106055997578559,3.31222899499851,1.5462143927925178,1.2997685753674266,1.783305087665594,0.07368496760344917
| 3,447
|
Metalloprotease
| 9
| 39
| 2.640319
| 0.008283
|
O75844,P02786,Q9NZ08,P42892,Q10713,Q7Z2K6,Q99797,Q9UIQ6,P55786
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
64,1,198,37,102,40,232,23,90
|
1683,2680,588,1516,804,64,654,1,2880,3328,2197,2397,806,3080,1158,37,2328,1476,90,102,3085,3134,470,450,3214,40,2661,639,286,1982,2712,1052,232,2615,436,2863,198,23,976
|
-0.13543039550688563,-0.5777501510624806,0.5661520429850156,-0.05613225744942473,0.3495825824320858,2.9500592169623037,0.4948313489884187,6.163282040099825,-0.6938776197516214,-1.2159763235501515,-0.3523458255088766,-0.43583767226307185,0.3495825824320858,-0.8424631282046733,0.12481764303170995,3.4487695757462786,-0.4078721182203763,-0.029937337355577215,2.635145909771866,2.46310203854336,-0.8424631282046733,-0.9030103721202933,0.7293444986172449,0.7523010836930542,-0.9950727563608438,3.3732566413381613,-0.5490844868874409,0.5186994533961014,1.2153931970579401,-0.24287217557351562,-0.5777501510624806,0.20069322429525754,1.444713076909665,-0.5205619963614778,0.7979543947770469,-0.6646226489620753,1.6658789469386504,3.699372205651011,0.2507402549882607
| 3,447
|
Hormone metabolic process
| 6
| 28
| 2.63586
| 0.008392
|
O75844,Q9UBM7,O95470,P42892,P30536,Q9HB40
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,129,33,37,6,48
|
2577,64,33,551,2197,2737,615,6,37,3350,1204,3344,757,2844,290,134,955,1045,1542,2363,2762,1845,2907,48,1506,129,3145,2378
|
-0.5205619963614778,2.9500592169623037,3.5085760309399507,0.6132320530882964,-0.3523458255088766,-0.6065606205962223,0.5424727361776948,4.542704790332735,3.4487695757462786,-1.280739952990378,0.09930691761130685,-1.2482633580866476,0.39839338050516404,-0.6646226489620753,1.1941177625102746,2.1230475619495595,0.2507402549882607,0.20069322429525754,-0.05613225744942473,-0.4078721182203763,-0.6065606205962223,-0.18890262528843013,-0.6938776197516214,3.31222899499851,-0.029937337355577215,2.1597019144209066,-0.9030103721202933,-0.4078721182203763
| 3,447
|
Mitochondrial myopathy
| 7
| 30
| 2.628395
| 0.008579
|
Q96CU9,Q86Y39,Q9Y6M9,O75306,P03886,Q9NP80,O43676
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
4,230,257,105,15,122,29
|
2439,29,833,1518,105,2578,1687,713,338,15,2391,748,2080,3079,3331,1202,2091,1430,764,230,4,2420,1272,1178,122,583,2622,2066,2511,257
|
-0.46394015097449753,3.5973040673963035,0.32502601874310844,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,-0.13543039550688563,0.42264946952153903,0.99924807807911,3.9689451889376715,-0.43583767226307185,0.39839338050516404,-0.2973496050355208,-0.8424631282046733,-1.2159763235501515,0.09930691761130685,-0.2973496050355208,-0.0038593161671487642,0.39839338050516404,1.444713076909665,4.904690951021535,-0.43583767226307185,0.07368496760344917,0.12481764303170995,2.3042597288135043,0.5897382077871124,-0.5205619963614778,-0.2700467318806754,-0.46394015097449753,1.3206836082734048
| 3,447
|
Organic acid transmembrane transporter activity
| 14
| 23
| 2.62284
| 0.00872
|
Q9H2D1,P33527,P08183,Q15758,P08195,O75746,Q9UBX3,O14745,P30825,Q9Y619,P53985,Q02978,P41440,Q96NB2
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
66,348,131,759,630,506,199,575,138,107,47,496,119,703
|
575,1112,506,1876,131,630,138,348,119,3307,47,496,759,1974,1007,703,1053,66,1853,799,199,860,107
|
0.5897382077871124,0.15021822725387687,0.6599460191541926,-0.21582458354418593,2.141400980540596,0.5186994533961014,2.067668972449665,0.977207970824741,2.3221030889708456,-1.1519610734492034,3.31222899499851,0.6831677294955423,0.39839338050516404,-0.24287217557351562,0.22576972351761432,0.44680723292840124,0.20069322429525754,2.9176116047506313,-0.18890262528843013,0.3740380583531353,1.6658789469386504,0.32502601874310844,2.4281394545085906
| 3,447
|
Lipid biosynthesis
| 20
| 58
| 2.621877
| 0.008745
|
Q9UBM7,P49327,P37268,P35790,P53602,Q15392,Q96G23,Q53GQ0,O76062,P48449,O00116,Q15800,Q16850,P27544,Q9H3P7,Q9BY49,O75845,Q8IVS2,Q96N66,Q9NZ01
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
129,132,8,143,400,147,148,290,165,42,305,52,185,60,322,95,227,231,361,244
|
305,3436,2570,227,165,904,3009,3431,1027,60,143,8,2886,42,1118,132,1635,2029,400,1302,841,3234,3438,2161,3310,727,1767,3107,818,147,1593,52,185,290,793,602,231,1542,1046,1267,2762,1549,148,361,2992,890,95,322,438,539,541,2954,2429,244,972,129,1862,973
|
1.1082724828312556,-2.9021986504963437,-0.5205619963614778,1.4651460309893183,1.8412078293006888,0.2756058236423961,-0.782559488471584,-2.2399728259652774,0.20069322429525754,2.9823482482966575,2.0304811478621976,4.308266492154955,-0.6938776197516214,3.35805169719967,0.15021822725387687,2.141400980540596,-0.10887756899447036,-0.2700467318806754,0.8657956397936897,0.04795069293778851,0.32502601874310844,-1.0260995428738104,-3.126119720766466,-0.32478217017330907,-1.1519610734492034,0.42264946952153903,-0.16210499188174082,-0.8726553252537929,0.3495825824320858,1.9930749898852833,-0.08244526537605792,3.250640313041074,1.7444059316466967,1.1941177625102746,0.3740380583531353,0.5661520429850156,1.444713076909665,-0.05613225744942473,0.20069322429525754,0.07368496760344917,-0.6065606205962223,-0.05613225744942473,1.9930749898852833,0.9550879611029554,-0.7528442383323635,0.3003674196569163,2.515194930023786,1.0648954266698725,0.7979543947770469,0.6366343901410989,0.6366343901410989,-0.7232842213033084,-0.43583767226307185,1.3623028978368232,0.2507402549882607,2.1597019144209066,-0.18890262528843013,0.2507402549882607
| 3,447
|
Sterol biosynthetic process
| 7
| 27
| 2.614785
| 0.008928
|
Q9UBM7,O76062,P37268,P48449,Q15392,Q15800,Q16850
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,165,8,42,147,52,185
|
1397,227,165,1400,3009,2633,1027,615,8,2745,42,2029,400,841,3234,2161,3310,726,727,1767,3107,147,1593,52,185,129,973
|
-0.0038593161671487642,1.4651460309893183,1.8412078293006888,-0.0038593161671487642,-0.782559488471584,-0.5490844868874409,0.20069322429525754,0.5424727361776948,4.308266492154955,-0.6065606205962223,3.35805169719967,-0.2700467318806754,0.8657956397936897,0.32502601874310844,-1.0260995428738104,-0.32478217017330907,-1.1519610734492034,0.42264946952153903,0.42264946952153903,-0.16210499188174082,-0.8726553252537929,1.9930749898852833,-0.08244526537605792,3.250640313041074,1.7444059316466967,2.1597019144209066,0.2507402549882607
| 3,447
|
Macromolecule transmembrane transporter activity
| 7
| 12
| 2.611671
| 0.00901
|
Q99595,P51991,Q15388,P49755,O14925,Q9NS69,O60830
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
32,377,139,399,240,19,57
|
240,57,446,714,399,377,914,678,139,32,19,670
|
1.3830082140752036,3.0782810890943333,0.7523010836930542,0.42264946952153903,0.8657956397936897,0.9106055997578559,0.2756058236423961,0.4708675653967537,2.067668972449665,3.5234451642020086,3.856733849716352,0.4948313489884187
| 3,447
|
Apical plasma membrane
| 18
| 45
| 2.608694
| 0.009089
|
Q9Y6M7,P33527,P08183,P08195,O75955,Q86UE4,O14745,Q16181,P30825,O43865,Q16625,Q99797,P51790,P53985,P41440,P36551,P05023,Q12959
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
585,348,131,630,550,195,575,392,138,74,351,232,619,47,119,429,551,285
|
2008,575,2516,74,550,981,551,836,131,630,2777,1520,783,3265,1346,1240,750,1947,675,1407,138,348,989,1473,429,1634,119,619,47,1416,1162,1818,285,2161,2042,392,351,195,232,1733,1102,2562,1558,3434,585
|
-0.2700467318806754,0.5897382077871124,-0.4921810762200194,2.7861995187828263,0.6132320530882964,0.22576972351761432,0.6132320530882964,0.32502601874310844,2.141400980540596,0.5186994533961014,-0.6355175563328855,-0.05613225744942473,0.3740380583531353,-1.088674970956618,0.02210297651221063,0.07368496760344917,0.39839338050516404,-0.24287217557351562,0.4708675653967537,-0.0038593161671487642,2.067668972449665,0.977207970824741,0.22576972351761432,-0.029937337355577215,0.7979543947770469,-0.10887756899447036,2.3221030889708456,0.5424727361776948,3.31222899499851,-0.0038593161671487642,0.12481764303170995,-0.18890262528843013,1.2153931970579401,-0.32478217017330907,-0.2700467318806754,0.888241909646759,0.977207970824741,1.6658789469386504,1.444713076909665,-0.13543039550688563,0.1755097373274426,-0.4921810762200194,-0.05613225744942473,-2.6023424711782943,0.5897382077871124
| 3,447
|
Nadh dehydrogenase complex
| 6
| 25
| 2.603347
| 0.009232
|
Q96CU9,Q86Y39,O75306,P03886,Q9P0J0,O43676
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
4,230,105,15,184,29
|
2439,1111,29,1872,1518,105,2578,674,1687,477,1149,2015,713,15,2391,2080,3079,3331,721,562,2216,230,4,184,257
|
-0.46394015097449753,0.15021822725387687,3.5973040673963035,-0.21582458354418593,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,0.4708675653967537,-0.13543039550688563,0.706300299890814,0.12481764303170995,-0.2700467318806754,0.42264946952153903,3.9689451889376715,-0.43583767226307185,-0.2973496050355208,-0.8424631282046733,-1.2159763235501515,0.42264946952153903,0.6132320530882964,-0.3523458255088766,1.444713076909665,4.904690951021535,1.7638855180459252,1.3206836082734048
| 3,447
|
Metalloexopeptidase activity
| 10
| 20
| 2.602183
| 0.009263
|
O75844,P02786,Q9NZ08,Q6P179,Q7Z2K6,O75976,Q969V3,Q9UIQ6,P36551,P55786
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,1,198,450,40,266,113,23,429,90
|
64,266,1,447,3328,3080,429,1949,90,450,40,113,2712,3296,3113,1330,2673,2863,198,23
|
2.9500592169623037,1.278782566805988,6.163282040099825,0.7523010836930542,-1.2159763235501515,-0.8424631282046733,0.7979543947770469,-0.24287217557351562,2.635145909771866,0.7523010836930542,3.3732566413381613,2.3753388484773885,-0.5777501510624806,-1.1202280506221005,-0.8726553252537929,0.04795069293778851,-0.5490844868874409,-0.6646226489620753,1.6658789469386504,3.699372205651011
| 3,447
|
Dementia
| 19
| 61
| 2.600391
| 0.009312
|
P03886,P35637,Q9Y487,P61916,P04350,P27544,P22626,O15118,Q14108,P17900,P43243,P00403,P07602,Q9NQZ5,P31483,P21912,O76024,Q6Y7W6,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
15,150,159,420,173,60,317,67,70,448,466,338,339,216,358,236,235,369,245
|
1192,67,1396,833,2964,235,714,338,15,2391,245,3206,173,905,2313,339,782,2584,448,479,236,317,2636,60,2400,358,150,1473,1634,3287,466,1203,2091,723,2463,420,3157,1708,634,1422,2102,70,1256,1971,369,794,764,665,1603,1267,1605,1788,2420,3389,3029,216,3092,571,897,1060,159
|
0.09930691761130685,2.885003643625329,-0.0038593161671487642,0.32502601874310844,-0.7528442383323635,1.4036446740202682,0.42264946952153903,0.99924807807911,3.9689451889376715,-0.43583767226307185,1.341528204791294,-0.9950727563608438,1.783305087665594,0.2756058236423961,-0.4078721182203763,0.99924807807911,0.3740380583531353,-0.5205619963614778,0.7523010836930542,0.706300299890814,1.4036446740202682,1.0648954266698725,-0.5490844868874409,2.9823482482966575,-0.43583767226307185,0.9550879611029554,1.9554475850393123,-0.029937337355577215,-0.10887756899447036,-1.1202280506221005,0.7293444986172449,0.09930691761130685,-0.2973496050355208,0.42264946952153903,-0.46394015097449753,0.8206525871716301,-0.933530264018968,-0.13543039550688563,0.5186994533961014,-0.0038593161671487642,-0.2973496050355208,2.8522335346715137,0.07368496760344917,-0.24287217557351562,0.9328873923979636,0.3740380583531353,0.39839338050516404,0.4948313489884187,-0.08244526537605792,0.07368496760344917,-0.08244526537605792,-0.16210499188174082,-0.43583767226307185,-1.479725735965493,-0.782559488471584,1.5462143927925178,-0.8424631282046733,0.6132320530882964,0.3003674196569163,0.20069322429525754,1.87951707419191
| 3,447
|
Negative regulation of mrna metabolic process
| 17
| 48
| 2.598778
| 0.009356
|
Q13242,P38159,O60506,O75494,Q14011,Q06787,P22626,Q99729,Q16629,P07910,P35637,Q14103,Q6PJT7,Q92804,P61978,Q13151,P98175
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
529,161,225,445,168,634,317,234,561,367,150,340,601,187,284,558,528
|
1235,2627,225,1290,445,1025,367,655,1883,317,1470,1242,150,161,1414,284,1247,528,1579,634,1250,1532,1761,2839,1822,1422,558,529,1079,168,340,2896,1041,2658,561,998,1082,601,2354,3273,2663,187,1849,234,1271,1554,1509,802
|
0.07368496760344917,-0.5490844868874409,1.4651460309893183,0.04795069293778851,0.7523010836930542,0.20069322429525754,0.9328873923979636,0.4948313489884187,-0.21582458354418593,1.0648954266698725,-0.029937337355577215,0.07368496760344917,1.9554475850393123,1.8603914432017374,-0.0038593161671487642,1.2153931970579401,0.07368496760344917,0.6366343901410989,-0.08244526537605792,0.5186994533961014,0.07368496760344917,-0.05613225744942473,-0.16210499188174082,-0.6646226489620753,-0.18890262528843013,-0.0038593161671487642,0.6132320530882964,0.6366343901410989,0.1755097373274426,1.8219658343840837,0.99924807807911,-0.6938776197516214,0.20069322429525754,-0.5490844868874409,0.6132320530882964,0.22576972351761432,0.1755097373274426,0.5661520429850156,-0.4078721182203763,-1.088674970956618,-0.5490844868874409,1.7444059316466967,-0.18890262528843013,1.4242127921315773,0.07368496760344917,-0.05613225744942473,-0.029937337355577215,0.3740380583531353
| 3,447
|
Primary mitochondrial disease
| 21
| 97
| 2.589682
| 0.009606
|
P13073,Q96CU9,O95831,P03886,Q9Y2R0,O43676,Q70HW3,P20674,Q9P0J0,Q9UBX3,Q5XKP0,Q9H845,P00403,P08574,Q6DKK2,Q86Y39,Q99797,O75306,O14949,Q9NYY8,Q9Y6M9
|
Drugs and Diseases
|
Protein Atlas Disease involvement
|
protein_atlas_disease_involvement
|
250,4,373,15,27,29,35,417,184,199,328,473,338,463,98,230,232,105,108,388,257
|
2439,1111,108,29,1872,3359,935,833,1518,105,2578,1687,1236,865,2015,373,338,15,2391,1879,463,1521,748,250,1116,2080,417,806,1241,3079,2400,3349,1699,2692,753,2086,3331,1202,695,2532,2091,725,1642,1893,1250,2216,3108,1430,997,1971,483,2279,328,98,35,1597,764,2483,230,1977,1837,1003,3139,1439,1320,4,1050,606,644,2420,232,2908,1053,1500,1272,706,1014,473,2176,583,388,2622,184,2433,199,831,1190,27,649,1283,2066,3279,2566,650,712,2511,257
|
-0.46394015097449753,0.15021822725387687,2.4105871078712475,3.5973040673963035,-0.21582458354418593,-1.3462719949496813,0.2507402549882607,0.32502601874310844,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,-0.13543039550688563,0.07368496760344917,0.3003674196569163,-0.2700467318806754,0.9106055997578559,0.99924807807911,3.9689451889376715,-0.43583767226307185,-0.21582458354418593,0.7293444986172449,-0.05613225744942473,0.39839338050516404,1.3206836082734048,0.15021822725387687,-0.2973496050355208,0.8206525871716301,0.3495825824320858,0.07368496760344917,-0.8424631282046733,-0.43583767226307185,-1.280739952990378,-0.13543039550688563,-0.5777501510624806,0.39839338050516404,-0.2973496050355208,-1.2159763235501515,0.09930691761130685,0.44680723292840124,-0.4921810762200194,-0.2973496050355208,0.42264946952153903,-0.10887756899447036,-0.21582458354418593,0.07368496760344917,-0.3523458255088766,-0.8726553252537929,-0.0038593161671487642,0.22576972351761432,-0.24287217557351562,0.706300299890814,-0.38004199286570056,1.0430911699330094,2.480512850439473,3.478739117626629,-0.08244526537605792,0.39839338050516404,-0.46394015097449753,1.444713076909665,-0.24287217557351562,-0.18890262528843013,0.22576972351761432,-0.9030103721202933,-0.0038593161671487642,0.04795069293778851,4.904690951021535,0.20069322429525754,0.5661520429850156,0.5186994533961014,-0.43583767226307185,1.444713076909665,-0.6938776197516214,0.20069322429525754,-0.029937337355577215,0.07368496760344917,0.44680723292840124,0.22576972351761432,0.7293444986172449,-0.32478217017330907,0.5897382077871124,0.9106055997578559,-0.5205619963614778,1.7638855180459252,-0.43583767226307185,1.6658789469386504,0.3495825824320858,0.12481764303170995,3.6558165597384233,0.5186994533961014,0.07368496760344917,-0.2700467318806754,-1.088674970956618,-0.4921810762200194,0.5186994533961014,0.44680723292840124,-0.46394015097449753,1.3206836082734048
| 3,447
|
Protein transmembrane import into intracellular organelle
| 6
| 13
| 2.588085
| 0.009651
|
Q99595,O95831,Q15388,O14925,O43615,O60830
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,373,139,240,212,57
|
240,212,57,864,446,373,714,2254,139,1167,1782,32,968
|
1.3830082140752036,1.5663180339062512,3.0782810890943333,0.3003674196569163,0.7523010836930542,0.9106055997578559,0.42264946952153903,-0.38004199286570056,2.067668972449665,0.12481764303170995,-0.16210499188174082,3.5234451642020086,0.2507402549882607
| 3,447
|
Calmodulin
| 7
| 14
| 2.583469
| 0.009781
|
P41208,O43852,P80303,Q9BPX6,Q14257,Q9BRK5,Q02818
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
251,160,106,278,115,182,28
|
160,407,525,251,724,106,28,115,1040,2480,1836,2710,278,182
|
1.8603914432017374,0.8432660990380526,0.6366343901410989,1.3206836082734048,0.42264946952153903,2.4281394545085906,3.6266234348142947,2.357642344565318,0.20069322429525754,-0.46394015097449753,-0.18890262528843013,-0.5777501510624806,1.2577250368668513,1.7638855180459252
| 3,447
|
Intracellular calcium-sensing protein
| 7
| 14
| 2.583469
| 0.009781
|
P41208,O43852,P80303,Q9BPX6,Q14257,Q9BRK5,Q02818
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
251,160,106,278,115,182,28
|
160,407,525,251,724,106,28,115,1040,2480,1836,2710,278,182
|
1.8603914432017374,0.8432660990380526,0.6366343901410989,1.3206836082734048,0.42264946952153903,2.4281394545085906,3.6266234348142947,2.357642344565318,0.20069322429525754,-0.46394015097449753,-0.18890262528843013,-0.5777501510624806,1.2577250368668513,1.7638855180459252
| 3,447
|
Lipid localization
| 32
| 82
| 2.581147
| 0.009847
|
P31751,P08183,P30536,Q8WTV0,P35790,Q9BUR5,P23786,Q9Y3D6,Q07954,P61916,Q9BQE5,Q9H6V9,Q9NZJ7,A0FGR8,Q86Y82,Q9Y679,Q99720,Q4KMQ2,O15118,Q14108,P17900,Q9UJZ1,P07602,O15260,P10909,P50416,P33527,Q7Z3C6,Q9H2V7,P04062,O43772,Q9NP80
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
375,131,6,16,143,667,21,153,154,420,43,570,571,673,701,439,63,580,67,70,448,612,339,587,222,594,348,359,114,245,118,122
|
673,3436,1112,67,587,118,1147,1289,2728,1626,1196,904,2683,3432,245,981,1691,339,3379,2685,131,222,783,1153,448,1885,2081,21,785,6,375,3184,348,947,143,2786,594,420,2269,1706,3131,842,2894,3344,154,2161,70,726,580,3377,921,1974,359,701,3402,1840,16,3063,2290,63,43,1447,667,2714,3313,3221,114,708,1101,570,122,2562,1103,571,1557,1280,1140,612,1560,1736,153,439
|
0.4708675653967537,-2.9021986504963437,0.15021822725387687,2.885003643625329,0.5661520429850156,2.3221030889708456,0.12481764303170995,0.04795069293778851,-0.6065606205962223,-0.10887756899447036,0.09930691761130685,0.2756058236423961,-0.5777501510624806,-2.357998717266434,1.341528204791294,0.22576972351761432,-0.13543039550688563,0.99924807807911,-1.4460567516253717,-0.5777501510624806,2.141400980540596,1.4855121512311098,0.3740380583531353,0.12481764303170995,0.7523010836930542,-0.21582458354418593,-0.2973496050355208,3.7713507579645107,0.3740380583531353,4.542704790332735,0.9106055997578559,-0.9642170344811924,0.977207970824741,0.2507402549882607,2.0304811478621976,-0.6355175563328855,0.5661520429850156,0.8206525871716301,-0.38004199286570056,-0.13543039550688563,-0.9030103721202933,0.32502601874310844,-0.6938776197516214,-1.2482633580866476,1.9175959588678502,-0.32478217017330907,2.8522335346715137,0.42264946952153903,0.5897382077871124,-1.4125933300875322,0.2756058236423961,-0.24287217557351562,0.9550879611029554,0.44680723292840124,-1.5819950927603335,-0.18890262528843013,3.95501878428734,-0.812431823101089,-0.38004199286570056,2.966223445923369,3.35805169719967,-0.0038593161671487642,0.4948313489884187,-0.5777501510624806,-1.1519610734492034,-0.9950727563608438,2.3753388484773885,0.44680723292840124,0.1755097373274426,0.6132320530882964,2.3042597288135043,-0.4921810762200194,0.1755097373274426,0.6132320530882964,-0.05613225744942473,0.07368496760344917,0.15021822725387687,0.5661520429850156,-0.05613225744942473,-0.13543039550688563,1.9365499879520078,0.7979543947770469
| 3,447
|
Endoplasmic reticulum lumen
| 26
| 61
| 2.579683
| 0.009889
|
P07942,Q13217,Q9NWM8,O60568,Q02818,O43852,P30040,Q07065,O75718,O43493,P07237,Q9NZ08,Q6P179,Q7Z4H8,Q8TED1,Q9BS26,P27361,Q9NYU2,P10909,Q9Y680,O95881,O76024,Q14257,Q32P28,Q9BTY2,Q13438
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
374,636,149,404,28,160,552,442,690,687,691,198,450,731,734,608,465,740,222,97,100,235,115,117,256,252
|
1801,1112,687,1396,160,404,690,235,100,905,691,374,3229,222,1293,716,1294,941,1240,3097,3151,465,1471,784,3153,552,1812,1032,1352,2030,1952,28,442,636,252,115,1360,877,1040,117,1648,450,2166,731,1131,957,1265,2224,734,1983,3440,1845,608,1662,256,149,740,198,1389,1191,97
|
-0.18890262528843013,0.15021822725387687,0.44680723292840124,-0.0038593161671487642,1.8603914432017374,0.8432660990380526,0.44680723292840124,1.4036446740202682,2.46310203854336,0.2756058236423961,0.44680723292840124,0.9106055997578559,-1.0260995428738104,1.4855121512311098,0.04795069293778851,0.42264946952153903,0.04795069293778851,0.2507402549882607,0.07368496760344917,-0.8726553252537929,-0.933530264018968,0.7293444986172449,-0.029937337355577215,0.3740380583531353,-0.933530264018968,0.6132320530882964,-0.18890262528843013,0.20069322429525754,0.02210297651221063,-0.2700467318806754,-0.24287217557351562,3.6266234348142947,0.7751708030625595,0.5186994533961014,1.3206836082734048,2.357642344565318,0.02210297651221063,0.3003674196569163,0.20069322429525754,2.3398971923183667,-0.10887756899447036,0.7523010836930542,-0.32478217017330907,0.42264946952153903,0.15021822725387687,0.2507402549882607,0.07368496760344917,-0.3523458255088766,0.42264946952153903,-0.24287217557351562,-3.845785240619678,-0.18890262528843013,0.5661520429850156,-0.10887756899447036,1.3206836082734048,1.9742891277751569,0.42264946952153903,1.6658789469386504,0.02210297651221063,0.12481764303170995,2.515194930023786
| 3,447
|
Blindness
| 16
| 76
| 2.579189
| 0.009903
|
Q9H6K4,P49327,Q96CU9,O43505,Q9NZ08,P00558,Q86Y39,O75306,P21912,P50897,P03886,Q5SZK8,Q15058,Q9Y6M9,O43676,Q6P2Q9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
323,132,4,130,198,39,230,105,236,144,15,177,83,257,29,319
|
1461,1285,2439,2012,1339,130,29,978,1518,105,2578,1687,1805,2144,2449,713,39,15,2312,3262,2313,339,3379,1879,1402,448,2080,2397,1157,236,3303,3079,2400,3286,1243,3231,752,3017,132,2529,3331,3082,144,2646,1073,992,2091,1355,1249,2339,2939,2940,83,697,177,319,1261,230,1779,885,962,1094,605,4,771,2907,1272,323,583,1857,198,571,2622,2064,3398,257
|
-0.029937337355577215,0.04795069293778851,-0.46394015097449753,-0.2700467318806754,0.02210297651221063,2.141400980540596,3.5973040673963035,0.22576972351761432,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,-0.13543039550688563,-0.18890262528843013,-0.32478217017330907,-0.46394015097449753,0.42264946952153903,3.3732566413381613,3.9689451889376715,-0.4078721182203763,-1.088674970956618,-0.4078721182203763,0.99924807807911,-1.4460567516253717,-0.21582458354418593,-0.0038593161671487642,0.7523010836930542,-0.2973496050355208,-0.43583767226307185,0.12481764303170995,1.4036446740202682,-1.1519610734492034,-0.8424631282046733,-0.43583767226307185,-1.1202280506221005,0.07368496760344917,-1.0260995428738104,0.39839338050516404,-0.782559488471584,2.141400980540596,-0.4921810762200194,-1.2159763235501515,-0.8424631282046733,2.0304811478621976,-0.5490844868874409,0.1755097373274426,0.22576972351761432,-0.2973496050355208,0.02210297651221063,0.07368496760344917,-0.4078721182203763,-0.7232842213033084,-0.7232842213033084,2.7027116151259793,0.44680723292840124,1.783305087665594,1.0648954266698725,0.07368496760344917,1.444713076909665,-0.16210499188174082,0.3003674196569163,0.2507402549882607,0.1755097373274426,0.5661520429850156,4.904690951021535,0.39839338050516404,-0.6938776197516214,0.07368496760344917,1.0648954266698725,0.5897382077871124,-0.18890262528843013,1.6658789469386504,0.6132320530882964,-0.5205619963614778,-0.2700467318806754,-1.5476919401678764,1.3206836082734048
| 3,447
|
mRNA processing factor
| 23
| 76
| 2.574014
| 0.010053
|
P33240,Q8WXF1,P35637,Q13242,P38159,P23246,Q14011,P62995,Q16629,Q15233,Q92804,Q01844,Q6P2Q9,O75494,Q07666,Q96PK6,Q12874,Q07955,O95453,Q13595,Q9BWF3,P98179,Q96PU8
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
508,393,150,529,161,288,168,303,561,560,187,190,319,445,449,334,206,481,365,498,383,123,514
|
1463,2012,1339,1515,2140,1023,445,779,1066,2449,365,1345,1197,983,1522,987,288,508,150,161,2089,755,756,1954,2094,2979,303,875,123,190,449,481,1532,1896,2158,2839,206,1421,2160,529,2406,1079,498,168,2274,560,2896,1715,1258,1126,661,3235,561,319,1263,1264,851,2221,962,393,187,2493,1445,1986,334,514,2366,383,609,1553,2234,800,1232,2003,1866,1336
|
-0.029937337355577215,-0.2700467318806754,0.02210297651221063,-0.05613225744942473,-0.32478217017330907,0.20069322429525754,0.7523010836930542,0.3740380583531353,0.1755097373274426,-0.46394015097449753,0.9328873923979636,0.02210297651221063,0.09930691761130685,0.22576972351761432,-0.05613225744942473,0.22576972351761432,1.1941177625102746,0.6599460191541926,1.9554475850393123,1.8603914432017374,-0.2973496050355208,0.39839338050516404,0.39839338050516404,-0.24287217557351562,-0.2973496050355208,-0.7528442383323635,1.129846507529864,0.3003674196569163,2.2684240002799623,1.7052650235202231,0.7523010836930542,0.706300299890814,-0.05613225744942473,-0.21582458354418593,-0.32478217017330907,-0.6646226489620753,1.6063324809623214,-0.0038593161671487642,-0.32478217017330907,0.6366343901410989,-0.43583767226307185,0.1755097373274426,0.6831677294955423,1.8219658343840837,-0.38004199286570056,0.6132320530882964,-0.6938776197516214,-0.13543039550688563,0.07368496760344917,0.15021822725387687,0.4948313489884187,-1.0260995428738104,0.6132320530882964,1.0648954266698725,0.07368496760344917,0.07368496760344917,0.32502601874310844,-0.3523458255088766,0.2507402549882607,0.888241909646759,1.7444059316466967,-0.46394015097449753,-0.0038593161671487642,-0.24287217557351562,1.021208931090401,0.6599460191541926,-0.4078721182203763,0.9106055997578559,0.5661520429850156,-0.05613225744942473,-0.3523458255088766,0.3740380583531353,0.09930691761130685,-0.24287217557351562,-0.18890262528843013,0.04795069293778851
| 3,447
|
Golgi cisterna membrane
| 10
| 20
| 2.572323
| 0.010102
|
Q10713,Q15363,Q96L58,Q08379,Q10472,Q9Y3A3,O00461,P98194,Q9H4A6,Q8NBZ7
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
102,233,607,299,421,573,46,495,516,94
|
46,1745,809,495,2938,299,815,421,102,233,94,1545,1092,702,607,1223,516,610,2181,573
|
3.31222899499851,-0.16210499188174082,0.3495825824320858,0.6831677294955423,-0.7232842213033084,1.1513450009278545,0.3495825824320858,0.8206525871716301,2.46310203854336,1.4242127921315773,2.5496928079060073,-0.05613225744942473,0.1755097373274426,0.44680723292840124,0.5661520429850156,0.09930691761130685,0.6599460191541926,0.5661520429850156,-0.32478217017330907,0.6132320530882964
| 3,447
|
Mitophagy
| 6
| 11
| 2.568357
| 0.010218
|
P21796,Q8IWA4,Q15388,O94826,Q9NS69,Q8N4H5
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
3,451,139,446,19,84
|
446,476,714,2925,3,1122,139,451,84,1321,19
|
0.7523010836930542,0.706300299890814,0.42264946952153903,-0.7232842213033084,5.00137826845172,0.15021822725387687,2.067668972449665,0.7523010836930542,2.7027116151259793,0.04795069293778851,3.856733849716352
| 3,447
|
Steroid metabolic process
| 17
| 72
| 2.563331
| 0.010367
|
Q9UBM7,O95470,O75845,O15118,O76062,P30536,P37268,Q9BQE5,P48449,P38435,Q8WTV0,Q15392,Q15800,P04062,P49748,Q16850,Q53GQ0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,33,227,67,165,6,8,43,42,174,16,147,52,245,86,185,290
|
1112,67,1397,227,165,1400,33,3009,3432,245,551,905,3319,2633,1027,2737,615,1885,2081,3303,2635,785,6,947,8,174,3443,2745,42,86,1203,1204,2029,400,841,420,3131,3234,1580,757,2161,2102,3310,726,727,2409,1767,3107,147,661,2844,1593,52,185,290,921,1980,1542,16,2762,3063,2290,2907,43,890,322,708,129,1280,1735,973,3145
|
0.15021822725387687,2.885003643625329,-0.0038593161671487642,1.4651460309893183,1.8412078293006888,-0.0038593161671487642,3.5085760309399507,-0.782559488471584,-2.357998717266434,1.341528204791294,0.6132320530882964,0.2756058236423961,-1.1838763713319127,-0.5490844868874409,0.20069322429525754,-0.6065606205962223,0.5424727361776948,-0.21582458354418593,-0.2973496050355208,-1.1519610734492034,-0.5490844868874409,0.3740380583531353,4.542704790332735,0.2507402549882607,4.308266492154955,1.783305087665594,-6.679828795947688,-0.6065606205962223,3.35805169719967,2.6690160857083316,0.09930691761130685,0.09930691761130685,-0.2700467318806754,0.8657956397936897,0.32502601874310844,0.8206525871716301,-0.9030103721202933,-1.0260995428738104,-0.08244526537605792,0.39839338050516404,-0.32478217017330907,-0.2973496050355208,-1.1519610734492034,0.42264946952153903,0.42264946952153903,-0.43583767226307185,-0.16210499188174082,-0.8726553252537929,1.9930749898852833,0.4948313489884187,-0.6646226489620753,-0.08244526537605792,3.250640313041074,1.7444059316466967,1.1941177625102746,0.2756058236423961,-0.24287217557351562,-0.05613225744942473,3.95501878428734,-0.6065606205962223,-0.812431823101089,-0.38004199286570056,-0.6938776197516214,3.35805169719967,0.3003674196569163,1.0648954266698725,0.44680723292840124,2.1597019144209066,0.07368496760344917,-0.13543039550688563,0.2507402549882607,-0.9030103721202933
| 3,447
|
Calcium-binding protein
| 7
| 18
| 2.561015
| 0.010437
|
P41208,O43852,P80303,P43307,Q9BRK5,Q14257,Q02818
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
251,160,106,82,182,115,28
|
160,407,1471,525,251,82,724,106,28,115,1040,2480,1836,2710,278,182,3312,2869
|
1.8603914432017374,0.8432660990380526,-0.029937337355577215,0.6366343901410989,1.3206836082734048,2.7027116151259793,0.42264946952153903,2.4281394545085906,3.6266234348142947,2.357642344565318,0.20069322429525754,-0.46394015097449753,-0.18890262528843013,-0.5777501510624806,1.2577250368668513,1.7638855180459252,-1.1519610734492034,-0.6646226489620753
| 3,447
|
Decreased activity of mitochondrial complex i
| 7
| 33
| 2.559767
| 0.010474
|
Q70HW3,Q9UBX3,Q96CU9,Q86Y39,O75306,P03886,O43676
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,199,4,230,105,15,29
|
2439,29,3359,1518,105,2578,1687,980,713,15,2080,3079,2692,3331,721,695,2532,997,2279,35,230,1320,4,966,644,1272,1014,473,583,2622,199,712,257
|
-0.46394015097449753,3.5973040673963035,-1.3462719949496813,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,-0.13543039550688563,0.22576972351761432,0.42264946952153903,3.9689451889376715,-0.2973496050355208,-0.8424631282046733,-0.5777501510624806,-1.2159763235501515,0.42264946952153903,0.44680723292840124,-0.4921810762200194,0.22576972351761432,-0.38004199286570056,3.478739117626629,1.444713076909665,0.04795069293778851,4.904690951021535,0.2507402549882607,0.5186994533961014,0.07368496760344917,0.22576972351761432,0.7293444986172449,0.5897382077871124,-0.5205619963614778,1.6658789469386504,0.44680723292840124,1.3206836082734048
| 3,447
|
Translocase
| 11
| 25
| 2.556177
| 0.010583
|
P33527,P08183,P06576,Q9HD20,P16615,O75306,P03886,P98194,P00403,P08574,Q13423
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
348,131,38,104,390,105,15,495,338,463,215
|
2439,1518,105,1687,338,15,2391,551,38,131,463,390,2080,750,675,3079,348,1634,753,3331,495,1959,215,1724,104
|
-0.46394015097449753,-0.05613225744942473,2.4281394545085906,-0.13543039550688563,0.99924807807911,3.9689451889376715,-0.43583767226307185,0.6132320530882964,3.4186660677529486,2.141400980540596,0.7293444986172449,0.888241909646759,-0.2973496050355208,0.39839338050516404,0.4708675653967537,-0.8424631282046733,0.977207970824741,-0.10887756899447036,0.39839338050516404,-1.2159763235501515,0.6831677294955423,-0.24287217557351562,1.5462143927925178,-0.13543039550688563,2.4456443351957327
| 3,447
|
Regulation of rna splicing
| 27
| 86
| 2.547728
| 0.010843
|
P31942,Q8IXT5,P35637,P52597,P51114,P61978,P98175,Q13242,P38159,Q14011,P62995,P52756,P22626,Q9UKA9,O75494,Q07666,P31943,P55795,Q15427,Q5BKZ1,P31483,Q07955,Q13595,Q9BWF3,P98179,Q13573,Q96PU8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
142,534,150,281,408,284,528,529,161,168,303,430,317,459,445,449,201,204,469,219,358,481,498,383,123,379,514
|
2627,2142,445,2016,1197,782,2020,1881,1156,943,987,317,1750,1470,1242,2637,358,142,201,150,161,1245,2088,408,720,281,430,1527,204,284,2936,303,3233,875,528,123,1579,3250,634,1250,449,481,1532,1896,1709,917,2839,529,2406,1079,379,498,168,1589,3021,1165,2896,469,661,561,1312,2542,219,2948,3273,534,851,2221,1842,1319,1376,1496,2119,514,3256,797,1271,383,1507,2295,1452,2180,459,1796,802,743
|
-0.5490844868874409,-0.32478217017330907,0.7523010836930542,-0.2700467318806754,0.09930691761130685,0.3740380583531353,-0.2700467318806754,-0.21582458354418593,0.12481764303170995,0.2507402549882607,0.22576972351761432,1.0648954266698725,-0.16210499188174082,-0.029937337355577215,0.07368496760344917,-0.5490844868874409,0.9550879611029554,2.0304811478621976,1.6460928822167984,1.9554475850393123,1.8603914432017374,0.07368496760344917,-0.2973496050355208,0.8432660990380526,0.42264946952153903,1.236595433267566,0.7979543947770469,-0.05613225744942473,1.6262442098001728,1.2153931970579401,-0.7232842213033084,1.129846507529864,-1.0260995428738104,0.3003674196569163,0.6366343901410989,2.2684240002799623,-0.08244526537605792,-1.0572995486724805,0.5186994533961014,0.07368496760344917,0.7523010836930542,0.706300299890814,-0.05613225744942473,-0.21582458354418593,-0.13543039550688563,0.2756058236423961,-0.6646226489620753,0.6366343901410989,-0.43583767226307185,0.1755097373274426,0.9106055997578559,0.6831677294955423,1.8219658343840837,-0.08244526537605792,-0.782559488471584,0.12481764303170995,-0.6938776197516214,0.7293444986172449,0.4948313489884187,0.6132320530882964,0.04795069293778851,-0.4921810762200194,1.505811928811038,-0.7232842213033084,-1.088674970956618,0.6366343901410989,0.32502601874310844,-0.3523458255088766,-0.18890262528843013,0.04795069293778851,0.02210297651221063,-0.029937337355577215,-0.2973496050355208,0.6599460191541926,-1.0572995486724805,0.3740380583531353,0.07368496760344917,0.9106055997578559,-0.029937337355577215,-0.38004199286570056,-0.0038593161671487642,-0.32478217017330907,0.7523010836930542,-0.16210499188174082,0.3740380583531353,0.42264946952153903
| 3,447
|
Serine hydrolase activity
| 9
| 21
| 2.547318
| 0.010855
|
Q4J6C6,Q2T9J0,P10619,Q86TI2,O75976,Q9HB40,P67812,Q16740,P42785
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
412,192,72,137,266,48,241,116,55
|
548,266,72,2779,3123,752,55,2693,1527,2030,241,116,192,412,470,953,820,137,773,668,48
|
0.6132320530882964,1.278782566805988,2.8027703309462138,-0.6355175563328855,-0.9030103721202933,0.39839338050516404,3.109952884310997,-0.5777501510624806,-0.05613225744942473,-0.2700467318806754,1.3830082140752036,2.3398971923183667,1.685602847740683,0.8432660990380526,0.7293444986172449,0.2507402549882607,0.3495825824320858,2.0861819039271947,0.39839338050516404,0.4948313489884187,3.31222899499851
| 3,447
|
Isoprenoid metabolic process
| 6
| 24
| 2.541927
| 0.011024
|
Q6NUM9,P51648,P37268,P48449,Q9HB40,Q9BY49
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
134,136,8,42,48,95
|
2577,1063,3264,1027,2737,8,42,136,400,420,3234,154,3310,3107,134,955,1977,1045,2363,95,1182,48,1506,2378
|
-0.5205619963614778,0.1755097373274426,-1.088674970956618,0.20069322429525754,-0.6065606205962223,4.308266492154955,3.35805169719967,2.104641317835198,0.8657956397936897,0.8206525871716301,-1.0260995428738104,1.9175959588678502,-1.1519610734492034,-0.8726553252537929,2.1230475619495595,0.2507402549882607,-0.24287217557351562,0.20069322429525754,-0.4078721182203763,2.515194930023786,0.12481764303170995,3.31222899499851,-0.029937337355577215,-0.4078721182203763
| 3,447
|
Phenotypic variability
| 25
| 101
| 2.539713
| 0.011094
|
P03886,O95470,Q70HW3,O14979,Q9H061,P04350,P00374,P57740,P36551,Q6P2Q9,Q8TD16,Q9BUF5,P17900,Q13885,Q9NR77,Q15427,Q15058,P43243,P00403,P07602,Q9BVA1,P07196,P21912,O95453,Q92733
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
15,33,35,169,45,173,51,431,429,319,453,197,448,76,81,469,83,466,338,339,355,221,236,365,254
|
2439,2009,1192,169,1287,833,1063,3007,476,365,33,51,338,835,15,2391,173,2251,221,339,2453,2777,2735,2019,783,448,236,1297,1243,719,429,1412,1634,3269,3017,2833,2460,2640,466,2889,1245,1159,787,2645,2263,1073,2091,3156,2463,2331,431,1306,1759,2703,634,3293,2339,2102,1359,2212,76,1360,83,1767,469,1168,1430,3253,2279,319,1649,1596,35,3139,453,1092,962,254,605,1320,197,355,45,1182,3222,2176,1926,81,2295,3092,571,897,3225,1231,1332,3398,1675,831,649,1739,976
|
-0.46394015097449753,-0.2700467318806754,0.09930691761130685,1.8026650560757604,0.04795069293778851,0.32502601874310844,0.1755097373274426,-0.782559488471584,0.706300299890814,0.9328873923979636,3.5085760309399507,3.266090717897094,0.99924807807911,0.32502601874310844,3.9689451889376715,-0.43583767226307185,1.783305087665594,-0.38004199286570056,1.4855121512311098,0.99924807807911,-0.46394015097449753,-0.6355175563328855,-0.6065606205962223,-0.2700467318806754,0.3740380583531353,0.7523010836930542,1.4036446740202682,0.04795069293778851,0.07368496760344917,0.42264946952153903,0.7979543947770469,-0.0038593161671487642,-0.10887756899447036,-1.088674970956618,-0.782559488471584,-0.6646226489620753,-0.46394015097449753,-0.5490844868874409,0.7293444986172449,-0.6938776197516214,0.07368496760344917,0.12481764303170995,0.3740380583531353,-0.5490844868874409,-0.38004199286570056,0.1755097373274426,-0.2973496050355208,-0.933530264018968,-0.46394015097449753,-0.4078721182203763,0.7979543947770469,0.04795069293778851,-0.16210499188174082,-0.5777501510624806,0.5186994533961014,-1.1202280506221005,-0.4078721182203763,-0.2973496050355208,0.02210297651221063,-0.3523458255088766,2.769586772818807,0.02210297651221063,2.7027116151259793,-0.16210499188174082,0.7293444986172449,0.12481764303170995,-0.0038593161671487642,-1.0572995486724805,-0.38004199286570056,1.0648954266698725,-0.10887756899447036,-0.08244526537605792,3.478739117626629,-0.9030103721202933,0.7523010836930542,0.1755097373274426,0.2507402549882607,1.3206836082734048,0.5661520429850156,0.04795069293778851,1.6658789469386504,0.977207970824741,3.327538052125804,0.12481764303170995,-0.9950727563608438,-0.32478217017330907,-0.21582458354418593,2.7194945196309765,-0.38004199286570056,-0.8424631282046733,0.6132320530882964,0.3003674196569163,-0.9950727563608438,0.09930691761130685,0.04795069293778851,-1.5476919401678764,-0.10887756899447036,0.3495825824320858,0.5186994533961014,-0.13543039550688563,0.2507402549882607
| 3,447
|
Optic disc pallor
| 14
| 49
| 2.538159
| 0.011144
|
Q9H6K4,O95831,Q96CU9,Q6P4Q7,Q9NPL8,Q10713,Q86Y39,O95140,O75306,Q9H061,P03886,O43676,Q9Y6M9,P04439
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
323,373,4,423,583,102,230,476,105,45,15,29,257,524
|
2439,1192,3003,1145,2012,29,978,833,1518,105,2578,804,1687,1805,476,373,713,15,524,2455,2780,2080,2397,3079,3331,2646,3405,102,423,1435,230,1316,2551,885,962,1655,4,607,1272,1178,45,1181,1182,323,583,2622,1862,976,257
|
-0.46394015097449753,0.09930691761130685,-0.782559488471584,0.12481764303170995,-0.2700467318806754,3.5973040673963035,0.22576972351761432,0.32502601874310844,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,0.3495825824320858,-0.13543039550688563,-0.18890262528843013,0.706300299890814,0.9106055997578559,0.42264946952153903,3.9689451889376715,0.6366343901410989,-0.46394015097449753,-0.6355175563328855,-0.2973496050355208,-0.43583767226307185,-0.8424631282046733,-1.2159763235501515,-0.5490844868874409,-1.6165156774605418,2.46310203854336,0.8206525871716301,-0.0038593161671487642,1.444713076909665,0.04795069293778851,-0.4921810762200194,0.3003674196569163,0.2507402549882607,-0.10887756899447036,4.904690951021535,0.5661520429850156,0.07368496760344917,0.12481764303170995,3.327538052125804,0.12481764303170995,0.12481764303170995,1.0648954266698725,0.5897382077871124,-0.5205619963614778,-0.18890262528843013,0.2507402549882607,1.3206836082734048
| 3,447
|
Proton transmembrane transport
| 16
| 42
| 2.537196
| 0.011174
|
P36542,P13073,Q13423,P06576,O14745,Q96ES6,P20674,O75964,P51790,Q9UJZ1,P56385,P08574,P05023,O75947,Q9UDW1,P00403
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
592,250,215,38,575,171,417,44,619,612,270,463,551,522,124,338
|
1111,575,1287,1518,522,44,338,2391,551,1690,38,463,1069,748,250,417,1947,3048,988,1241,3051,1158,592,1473,1634,753,2933,619,1756,270,1818,1578,215,171,3389,645,1500,1853,124,2915,2065,612
|
0.15021822725387687,0.5897382077871124,0.04795069293778851,-0.05613225744942473,0.6366343901410989,3.342812226590406,0.99924807807911,-0.43583767226307185,0.6132320530882964,-0.13543039550688563,3.4186660677529486,0.7293444986172449,0.1755097373274426,0.39839338050516404,1.3206836082734048,0.8206525871716301,-0.24287217557351562,-0.812431823101089,0.22576972351761432,0.07368496760344917,-0.812431823101089,0.12481764303170995,0.5661520429850156,-0.029937337355577215,-0.10887756899447036,0.39839338050516404,-0.7232842213033084,0.5424727361776948,-0.16210499188174082,1.2577250368668513,-0.18890262528843013,-0.08244526537605792,1.5462143927925178,1.8026650560757604,-1.479725735965493,0.5186994533961014,-0.029937337355577215,-0.18890262528843013,2.232387500674451,-0.6938776197516214,-0.2700467318806754,0.5661520429850156
| 3,447
|
Glycerophospholipid biosynthesis
| 12
| 28
| 2.530919
| 0.011376
|
P40939,Q9NPH0,Q8N2A8,Q9HCL2,Q96N66,Q8IV08,Q9HBU6,P35790,Q8NCC3,Q9NQZ5,Q9NP80,P43304
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
376,2,162,541,361,170,539,143,20,216,122,283
|
1022,3149,904,2925,143,376,283,1118,2786,1635,2031,1122,1430,602,170,162,20,1046,361,3296,2992,3313,539,541,122,2,216,1862
|
0.20069322429525754,-0.933530264018968,0.2756058236423961,-0.7232842213033084,2.0304811478621976,0.9106055997578559,1.2153931970579401,0.15021822725387687,-0.6355175563328855,-0.10887756899447036,-0.2700467318806754,0.15021822725387687,-0.0038593161671487642,0.5661520429850156,1.8026650560757604,1.8603914432017374,3.842577248070439,0.20069322429525754,0.9550879611029554,-1.1202280506221005,-0.7528442383323635,-1.1519610734492034,0.6366343901410989,0.6366343901410989,2.3042597288135043,5.654984009268145,1.5462143927925178,-0.18890262528843013
| 3,447
|
Protein transmembrane transporter activity
| 9
| 11
| 2.528858
| 0.011443
|
Q99595,Q07820,O94826,Q15388,Q9UGP8,P49755,O14925,Q9NS69,O60830
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
32,678,446,139,670,399,240,19,57
|
240,57,446,714,399,914,678,139,32,19,670
|
1.3830082140752036,3.0782810890943333,0.7523010836930542,0.42264946952153903,0.8657956397936897,0.2756058236423961,0.4708675653967537,2.067668972449665,3.5234451642020086,3.856733849716352,0.4948313489884187
| 3,447
|
Endoplasmic reticulum golgi intermediate compartment membrane
| 11
| 26
| 2.527777
| 0.011479
|
P24390,Q15363,Q08379,Q10472,P49755,Q9Y282,Q15904,Q8N511,Q13190,Q9Y3B3,O15260
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
36,233,299,421,399,49,600,53,635,282,587
|
587,1566,1804,866,36,1471,1120,399,809,2030,2789,1959,299,421,876,635,233,600,53,680,1179,3089,1100,49,1109,282
|
0.5661520429850156,-0.08244526537605792,-0.18890262528843013,0.3003674196569163,3.463771008364262,-0.029937337355577215,0.15021822725387687,0.8657956397936897,0.3495825824320858,-0.2700467318806754,-0.6355175563328855,-0.24287217557351562,1.1513450009278545,0.8206525871716301,0.3003674196569163,0.5186994533961014,1.4242127921315773,0.5661520429850156,3.204073554666814,0.4708675653967537,0.12481764303170995,-0.8424631282046733,0.1755097373274426,3.2968848749628292,0.1755097373274426,1.236595433267566
| 3,447
|
Peptide binding
| 19
| 72
| 2.523944
| 0.011605
|
Q15388,P10321,Q8WTV0,Q15392,Q9UIQ6,Q07954,P24390,P42892,Q9H7Z7,Q9BYT8,O00264,Q9NQX7,O43731,Q9NZ08,Q6P179,P55786,P10909,Q99735,Q9NXR7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
139,398,16,147,23,154,36,37,438,436,300,314,188,198,450,90,222,362,387
|
1143,300,1110,2440,548,2821,3281,188,979,2072,446,3432,524,1520,906,398,222,2197,3414,3151,36,1471,3051,2690,1032,1117,2201,948,37,2262,2152,1701,1159,1034,2204,1527,90,2533,914,2652,1075,1959,2098,154,2156,1895,2467,1963,2753,2214,139,147,450,1783,16,2490,1656,1725,624,362,1990,436,1451,438,314,387,198,1932,1933,23,3278,2724
|
0.12481764303170995,1.129846507529864,0.15021822725387687,-0.46394015097449753,0.6132320530882964,-0.6646226489620753,-1.1202280506221005,1.7248659083694862,0.22576972351761432,-0.2973496050355208,0.7523010836930542,-2.357998717266434,0.6366343901410989,-0.05613225744942473,0.2756058236423961,0.8657956397936897,1.4855121512311098,-0.3523458255088766,-1.6862217513646123,-0.933530264018968,3.463771008364262,-0.029937337355577215,-0.812431823101089,-0.5777501510624806,0.20069322429525754,0.15021822725387687,-0.3523458255088766,0.2507402549882607,3.4487695757462786,-0.38004199286570056,-0.32478217017330907,-0.13543039550688563,0.12481764303170995,0.20069322429525754,-0.3523458255088766,-0.05613225744942473,2.635145909771866,-0.4921810762200194,0.2756058236423961,-0.5490844868874409,0.1755097373274426,-0.24287217557351562,-0.2973496050355208,1.9175959588678502,-0.32478217017330907,-0.21582458354418593,-0.46394015097449753,-0.24287217557351562,-0.6065606205962223,-0.3523458255088766,2.067668972449665,1.9930749898852833,0.7523010836930542,-0.16210499188174082,3.95501878428734,-0.46394015097449753,-0.10887756899447036,-0.13543039550688563,0.5424727361776948,0.9550879611029554,-0.24287217557351562,0.7979543947770469,-0.0038593161671487642,0.7979543947770469,1.086622325488035,0.9106055997578559,1.6658789469386504,-0.21582458354418593,-0.21582458354418593,3.699372205651011,-1.088674970956618,-0.5777501510624806
| 3,447
|
Intracellular protein transmembrane transport
| 8
| 22
| 2.523775
| 0.01161
|
Q15629,Q99595,P31751,O95831,Q15388,O14925,O43615,O60830
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,32,375,373,139,240,212,57
|
240,212,57,864,446,373,714,2254,985,375,2697,2533,914,139,128,1167,2801,1782,1661,32,968,670
|
1.3830082140752036,1.5663180339062512,3.0782810890943333,0.3003674196569163,0.7523010836930542,0.9106055997578559,0.42264946952153903,-0.38004199286570056,0.22576972351761432,0.9106055997578559,-0.5777501510624806,-0.4921810762200194,0.2756058236423961,2.067668972449665,2.1597019144209066,0.12481764303170995,-0.6355175563328855,-0.16210499188174082,-0.10887756899447036,3.5234451642020086,0.2507402549882607,0.4948313489884187
| 3,447
|
Huntingtons disease
| 21
| 82
| 2.523532
| 0.011618
|
P14406,P13073,P21796,P45880,O75947,O43676,P09669,P30876,P06576,P20674,Q16718,Q13561,Q9UJW0,P00403,P08574,O95168,O75306,O14949,P21912,Q9Y6M9,Q9UDW1
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
0,250,3,7,522,29,406,289,38,417,562,578,475,338,463,477,105,108,236,257,124
|
2439,1462,1111,108,3393,29,1872,1518,105,2578,674,1687,522,2250,477,1149,2015,1343,713,338,2018,1238,1690,38,463,906,406,1069,748,907,250,0,1116,942,2395,1028,2080,417,3,236,806,988,1750,1241,3320,3079,289,2400,1158,592,2784,3287,7,753,2933,3331,721,840,1574,3105,3342,1205,1075,1893,1759,1895,2601,578,1256,1164,3362,562,2216,2228,1725,2122,2497,124,475,1863,776,257
|
-0.46394015097449753,-0.029937337355577215,0.15021822725387687,2.4105871078712475,-1.5476919401678764,3.5973040673963035,-0.21582458354418593,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,0.4708675653967537,-0.13543039550688563,0.6366343901410989,-0.38004199286570056,0.706300299890814,0.12481764303170995,-0.2700467318806754,0.02210297651221063,0.42264946952153903,0.99924807807911,-0.2700467318806754,0.07368496760344917,-0.13543039550688563,3.4186660677529486,0.7293444986172449,0.2756058236423961,0.8432660990380526,0.1755097373274426,0.39839338050516404,0.2756058236423961,1.3206836082734048,6.3352481246556165,0.15021822725387687,0.2507402549882607,-0.43583767226307185,0.20069322429525754,-0.2973496050355208,0.8206525871716301,5.00137826845172,1.4036446740202682,0.3495825824320858,0.22576972351761432,-0.16210499188174082,0.07368496760344917,-1.1838763713319127,-0.8424631282046733,1.1941177625102746,-0.43583767226307185,0.12481764303170995,0.5661520429850156,-0.6355175563328855,-1.1202280506221005,4.465429303037878,0.39839338050516404,-0.7232842213033084,-1.2159763235501515,0.42264946952153903,0.32502601874310844,-0.08244526537605792,-0.8726553252537929,-1.2482633580866476,0.09930691761130685,0.1755097373274426,-0.21582458354418593,-0.16210499188174082,-0.21582458354418593,-0.5205619963614778,0.5897382077871124,0.07368496760344917,0.12481764303170995,-1.3462719949496813,0.6132320530882964,-0.3523458255088766,-0.3523458255088766,-0.13543039550688563,-0.2973496050355208,-0.46394015097449753,2.232387500674451,0.7293444986172449,-0.18890262528843013,0.39839338050516404,1.3206836082734048
| 3,447
|
Selective autophagy
| 11
| 32
| 2.52169
| 0.011679
|
P21796,Q8IWA4,Q9BUF5,Q15388,O94826,P04350,Q13885,P08670,Q9NS69,Q8N4H5,Q9BVA1
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
3,451,197,139,446,173,76,205,19,84,355
|
1871,1289,446,476,714,173,1026,205,2020,2925,3,1302,841,2463,3248,1122,556,2750,2600,918,76,2840,139,451,84,2904,1321,3389,197,355,19,1142
|
-0.21582458354418593,0.04795069293778851,0.7523010836930542,0.706300299890814,0.42264946952153903,1.783305087665594,0.20069322429525754,1.6063324809623214,-0.2700467318806754,-0.7232842213033084,5.00137826845172,0.04795069293778851,0.32502601874310844,-0.46394015097449753,-1.0572995486724805,0.15021822725387687,0.6132320530882964,-0.6065606205962223,-0.5205619963614778,0.2756058236423961,2.769586772818807,-0.6646226489620753,2.067668972449665,0.7523010836930542,2.7027116151259793,-0.6938776197516214,0.04795069293778851,-1.479725735965493,1.6658789469386504,0.977207970824741,3.856733849716352,0.15021822725387687
| 3,447
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 7
| 32
| 2.510407
| 0.012059
|
P09601,P30519,Q15800,O60341,Q32P28,Q16850,Q6UW02
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
68,17,52,85,117,185,218
|
2820,2570,85,404,1944,227,691,68,716,615,17,1417,1249,1897,726,52,185,117,2948,1833,218,2949,1777,1170,566,1438,538,3221,1612,975,2377,3279
|
-0.6646226489620753,-0.5205619963614778,2.6690160857083316,0.8432660990380526,-0.24287217557351562,1.4651460309893183,0.44680723292840124,2.885003643625329,0.42264946952153903,0.5424727361776948,3.94106406729976,-0.0038593161671487642,0.07368496760344917,-0.21582458354418593,0.42264946952153903,3.250640313041074,1.7444059316466967,2.3398971923183667,-0.7232842213033084,-0.18890262528843013,1.5260458493085034,-0.7232842213033084,-0.16210499188174082,0.12481764303170995,0.6132320530882964,-0.0038593161671487642,0.6366343901410989,-0.9950727563608438,-0.08244526537605792,0.2507402549882607,-0.4078721182203763,-1.088674970956618
| 3,447
|
Golgi cisterna
| 13
| 25
| 2.507624
| 0.012155
|
Q9H4A6,Q10713,Q15363,Q96L58,Q08379,Q10472,Q9Y3A3,O00461,P98194,O95249,P04439,Q8NBZ7,Q8TBA6
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
516,102,233,607,299,421,573,46,495,440,524,94,320
|
46,440,524,1745,809,495,2938,299,815,421,102,3362,233,879,94,320,1545,1092,702,607,1223,516,610,2181,573
|
3.31222899499851,0.7751708030625595,0.6366343901410989,-0.16210499188174082,0.3495825824320858,0.6831677294955423,-0.7232842213033084,1.1513450009278545,0.3495825824320858,0.8206525871716301,2.46310203854336,-1.3462719949496813,1.4242127921315773,0.3003674196569163,2.5496928079060073,1.0648954266698725,-0.05613225744942473,0.1755097373274426,0.44680723292840124,0.5661520429850156,0.09930691761130685,0.6599460191541926,0.5661520429850156,-0.32478217017330907,0.6132320530882964
| 3,447
|
Variable expressivity
| 20
| 82
| 2.507606
| 0.012155
|
P03886,O95470,Q70HW3,Q9H061,P04350,P00374,P57740,Q8TD16,Q9BUF5,P17900,Q13885,Q9NR77,Q15427,Q15058,P43243,P00403,P07602,Q9BVA1,P07196,O95453
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
15,33,35,45,173,51,431,453,197,448,76,81,469,83,466,338,339,355,221,365
|
2439,2009,1192,1287,1063,3007,476,365,33,51,338,835,15,2391,173,2251,221,339,2777,2735,2019,783,448,1297,719,1634,3269,3017,2833,2640,466,2889,1245,787,1073,2091,3156,2463,2331,431,1306,1759,2703,3293,2339,2102,1359,2212,76,1360,83,1767,469,1168,1430,3253,2279,1649,1596,35,3139,453,1092,1320,197,355,45,1182,3222,2176,1926,81,3092,571,3225,1231,3398,1675,831,649,1739,976
|
-0.46394015097449753,-0.2700467318806754,0.09930691761130685,0.04795069293778851,0.1755097373274426,-0.782559488471584,0.706300299890814,0.9328873923979636,3.5085760309399507,3.266090717897094,0.99924807807911,0.32502601874310844,3.9689451889376715,-0.43583767226307185,1.783305087665594,-0.38004199286570056,1.4855121512311098,0.99924807807911,-0.6355175563328855,-0.6065606205962223,-0.2700467318806754,0.3740380583531353,0.7523010836930542,0.04795069293778851,0.42264946952153903,-0.10887756899447036,-1.088674970956618,-0.782559488471584,-0.6646226489620753,-0.5490844868874409,0.7293444986172449,-0.6938776197516214,0.07368496760344917,0.3740380583531353,0.1755097373274426,-0.2973496050355208,-0.933530264018968,-0.46394015097449753,-0.4078721182203763,0.7979543947770469,0.04795069293778851,-0.16210499188174082,-0.5777501510624806,-1.1202280506221005,-0.4078721182203763,-0.2973496050355208,0.02210297651221063,-0.3523458255088766,2.769586772818807,0.02210297651221063,2.7027116151259793,-0.16210499188174082,0.7293444986172449,0.12481764303170995,-0.0038593161671487642,-1.0572995486724805,-0.38004199286570056,-0.10887756899447036,-0.08244526537605792,3.478739117626629,-0.9030103721202933,0.7523010836930542,0.1755097373274426,0.04795069293778851,1.6658789469386504,0.977207970824741,3.327538052125804,0.12481764303170995,-0.9950727563608438,-0.32478217017330907,-0.21582458354418593,2.7194945196309765,-0.8424631282046733,0.6132320530882964,-0.9950727563608438,0.09930691761130685,-1.5476919401678764,-0.10887756899447036,0.3495825824320858,0.5186994533961014,-0.13543039550688563,0.2507402549882607
| 3,447
|
Nephropathy
| 6
| 20
| 2.493448
| 0.012651
|
Q14108,Q10713,P03886,O76024,P57740,P00403
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
70,102,15,235,431,338
|
2009,235,338,2967,15,2391,1945,1411,429,2640,431,914,1576,102,70,1001,1603,1371,960,2232
|
-0.2700467318806754,1.4036446740202682,0.99924807807911,-0.7528442383323635,3.9689451889376715,-0.43583767226307185,-0.24287217557351562,-0.0038593161671487642,0.7979543947770469,-0.5490844868874409,0.7979543947770469,0.2756058236423961,-0.08244526537605792,2.46310203854336,2.8522335346715137,0.22576972351761432,-0.08244526537605792,0.02210297651221063,0.2507402549882607,-0.3523458255088766
| 3,447
|
Sphingolipid metabolism
| 6
| 10
| 2.492663
| 0.012679
|
O95470,Q06136,Q9NZ01,P04062,P07602,Q16880
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
33,109,244,245,339,253
|
685,1113,33,245,339,448,109,2102,253,244
|
0.44680723292840124,0.15021822725387687,3.5085760309399507,1.341528204791294,0.99924807807911,0.7523010836930542,2.3929870039150383,-0.2973496050355208,1.3206836082734048,1.3623028978368232
| 3,447
|
Nucleobase containing compound transmembrane transporter activity
| 9
| 14
| 2.487485
| 0.012865
|
P51991,Q9H2D1,Q9HC21,Q6KCM7,P41440,Q9BSK2,Q6NUK1,Q8TB61,P12235
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
377,66,540,274,119,58,698,223,748
|
1564,1147,1690,748,907,119,377,274,698,821,223,58,66,540
|
-0.08244526537605792,0.12481764303170995,-0.13543039550688563,0.39839338050516404,0.2756058236423961,2.3221030889708456,0.9106055997578559,1.2577250368668513,0.44680723292840124,0.3495825824320858,1.4855121512311098,3.0782810890943333,2.9176116047506313,0.6366343901410989
| 3,447
|
Ceramide metabolic process
| 6
| 21
| 2.486598
| 0.012897
|
O95470,Q96G23,Q8NCC3,P04062,P27544,Q16880
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,148,20,245,60,253
|
685,1113,33,245,1945,2313,3379,448,3097,60,1633,2894,2161,2102,253,1430,20,148,1325,277,1670
|
0.44680723292840124,0.15021822725387687,3.5085760309399507,1.341528204791294,-0.24287217557351562,-0.4078721182203763,-1.4460567516253717,0.7523010836930542,-0.8726553252537929,2.9823482482966575,-0.10887756899447036,-0.6938776197516214,-0.32478217017330907,-0.2973496050355208,1.3206836082734048,-0.0038593161671487642,3.842577248070439,1.9930749898852833,0.04795069293778851,1.2577250368668513,-0.10887756899447036
| 3,447
|
Oxidoreductase activity acting on the ch ch group of donors
| 15
| 31
| 2.481202
| 0.013094
|
Q14914,Q9UBM7,P49327,O76062,Q6NUM9,P21912,Q9H845,Q15067,Q9H7Z7,Q15392,Q9NZ01,P49748,P36551,Q8N4Q0,Q9BY49
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
350,129,132,165,134,236,473,110,438,147,244,86,429,186,95
|
2188,165,3319,3435,464,236,1751,2400,429,2325,132,86,1351,2462,727,350,110,147,134,622,186,603,1605,3217,2497,95,438,473,3259,244,129
|
-0.3523458255088766,1.8412078293006888,-1.1838763713319127,-2.8583845407454613,0.7293444986172449,1.4036446740202682,-0.16210499188174082,-0.43583767226307185,0.7979543947770469,-0.4078721182203763,2.141400980540596,2.6690160857083316,0.02210297651221063,-0.46394015097449753,0.42264946952153903,0.977207970824741,2.3929870039150383,1.9930749898852833,2.1230475619495595,0.5424727361776948,1.7444059316466967,0.5661520429850156,-0.08244526537605792,-0.9950727563608438,-0.46394015097449753,2.515194930023786,0.7979543947770469,0.7293444986172449,-1.0572995486724805,1.3623028978368232,2.1597019144209066
| 3,447
|
Oxidoreductase complex
| 11
| 61
| 2.47841
| 0.013197
|
Q96CU9,Q86Y39,O75306,O14949,P21912,P03886,O43169,Q9P0J0,Q9Y6M9,Q9UDW1,O43676
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
4,230,105,108,236,15,50,184,257,124,29
|
2439,2009,1111,108,50,29,1872,978,1518,105,2578,674,1687,477,1149,2015,713,3367,3009,15,2391,3263,691,1879,463,2019,2584,1880,1809,716,2827,1116,2080,236,806,1524,3122,3079,2400,869,1158,1412,2525,283,753,3331,3082,721,1819,1362,562,2216,952,230,2762,4,2497,184,124,831,257
|
-0.46394015097449753,-0.2700467318806754,0.15021822725387687,2.4105871078712475,3.266090717897094,3.5973040673963035,-0.21582458354418593,0.22576972351761432,-0.05613225744942473,2.4281394545085906,-0.5205619963614778,0.4708675653967537,-0.13543039550688563,0.706300299890814,0.12481764303170995,-0.2700467318806754,0.42264946952153903,-1.3793326613984922,-0.782559488471584,3.9689451889376715,-0.43583767226307185,-1.088674970956618,0.44680723292840124,-0.21582458354418593,0.7293444986172449,-0.2700467318806754,-0.5205619963614778,-0.21582458354418593,-0.18890262528843013,0.42264946952153903,-0.6646226489620753,0.15021822725387687,-0.2973496050355208,1.4036446740202682,0.3495825824320858,-0.05613225744942473,-0.9030103721202933,-0.8424631282046733,-0.43583767226307185,0.3003674196569163,0.12481764303170995,-0.0038593161671487642,-0.4921810762200194,1.2153931970579401,0.39839338050516404,-1.2159763235501515,-0.8424631282046733,0.42264946952153903,-0.18890262528843013,0.02210297651221063,0.6132320530882964,-0.3523458255088766,0.2507402549882607,1.444713076909665,-0.6065606205962223,4.904690951021535,-0.46394015097449753,1.7638855180459252,2.232387500674451,0.3495825824320858,1.3206836082734048
| 3,447
|
Subsets and Splits
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