term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carboxylic acid transport
| 15
| 35
| 3.019789
| 0.00253
|
P53985,Q9Y619,O15439,Q96EV8,P04083,Q96NB2,Q9H2J7,Q9NZJ7,Q15041,Q8TDW0,P30825,P07602,P41440,Q9UBX3,Q9BQT8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
225,130,413,294,296,459,402,205,339,408,305,28,379,30,95
|
413,655,815,1524,828,296,848,28,759,2686,2357,1090,305,379,1450,225,1781,1134,339,2859,599,2225,1375,408,294,459,503,95,402,695,205,30,1383,1348,130
|
0.9371314323192231,0.5299304956557244,0.34219686706793473,-0.15616800678718376,0.3285473948164417,1.2478186889019522,0.31486510761236025,3.418324905107978,0.4099575031857863,-0.8518788914948365,-0.6050071745182394,0.10558175302512113,1.2128218563732212,1.0103454814086226,-0.11169757381838322,1.4758017160295607,-0.29170612358688064,0.07708640378612587,1.1303178723762042,-1.0400000767620767,0.6215260224104379,-0.525046536969556,-0.06757235345286404,0.9616407296721227,1.259436758440911,0.8629648599038147,0.7625504930274744,2.287002000595034,0.9738559787002006,0.5034874488366304,1.5754968368419882,3.3943981532933445,-0.06757235345286404,-0.052939730621627525,1.9884673871689231
| 3,069
|
Nadh dehydrogenase complex assembly
| 8
| 28
| 3.017392
| 0.00255
|
Q9H061,Q9Y6M9,Q9P0J0,O43676,O96000,P03915,Q96CU9,Q15070
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
34,260,74,16,208,273,160,190
|
1471,1064,16,1568,1521,1144,922,478,1802,208,273,2768,1310,190,1111,2389,293,516,1850,160,1296,34,2321,1565,74,799,810,260
|
-0.12648242619790095,0.11977606936216245,3.590805302191555,-0.18600945144458284,-0.15616800678718376,0.06278501041697414,0.24595582673959437,0.8129788391133055,-0.3069674436057677,1.5314026455401484,1.317174902542949,-0.9195667969445095,-0.03834467281593642,1.6626768412225865,0.0913519243495543,-0.6211353495660349,1.259436758440911,0.7498733649115101,-0.3222698704241627,1.8226377360704582,-0.023786986148872924,3.2895471284615776,-0.5728876459442109,-0.17106914307245863,2.4870785513620435,0.3693979985962563,0.3558136826238937,1.397039326426985
| 3,069
|
Optic disc pallor
| 16
| 49
| 3.016616
| 0.002556
|
O60313,Q9H061,Q9Y6M9,Q86Y39,Q9H6K4,Q10713,O43676,Q9UG56,P00846,O96000,Q6P4Q7,Q9NPL8,P04439,Q8N183,Q9GZY8,Q96CU9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
414,34,260,293,67,226,16,145,18,208,307,252,498,516,412,160
|
1471,1517,2847,548,1385,16,1164,414,1521,1144,2084,1145,922,2299,906,1770,208,18,498,2457,1251,1415,2768,2148,3024,2749,226,1535,854,307,293,2991,516,1850,1155,1459,1876,160,1296,982,412,34,67,252,1565,145,810,1028,260
|
-0.12648242619790095,-0.15616800678718376,-1.0226379236492988,0.686061138987713,-0.08224273671363029,3.590805302191555,0.04844756194118684,0.9371314323192231,-0.15616800678718376,0.06278501041697414,-0.446196376754283,0.06278501041697414,0.24595582673959437,-0.5728876459442109,0.25980460342637235,-0.29170612358688064,1.5314026455401484,3.536485172574649,0.7625504930274744,-0.6697966741024561,-0.009266478234315357,-0.09695107734044302,-0.9195667969445095,-0.47760517435342253,-1.6838381886675047,-0.9025689417990336,1.4758017160295607,-0.15616800678718376,0.31486510761236025,1.2128218563732212,1.259436758440911,-1.398902708781335,0.7498733649115101,-0.3222698704241627,0.06278501041697414,-0.11169757381838322,-0.33761362784204135,1.8226377360704582,-0.023786986148872924,0.2042060940190475,0.9493992521351239,3.2895471284615776,2.5522463606903325,1.4196539730392503,-0.17106914307245863,1.8853889962920538,0.3558136826238937,0.16214771959355356,1.397039326426985
| 3,069
|
Membrane lipid catabolic process
| 6
| 12
| 3.015551
| 0.002565
|
O95470,P06280,P50897,P04062,Q13510,P17900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
162,230,2,103,46,123
|
162,103,1033,230,303,1104,123,2,1171,46,738,1408
|
1.8015665931551217,2.208903801378106,0.1480588764572703,1.4534088423165563,1.2128218563732212,0.0913519243495543,2.039317917817865,3.832785549048474,0.04844756194118684,2.9715906698002557,0.4502300599193025,-0.08224273671363029
| 3,069
|
Sphingolipid de novo biosynthesis
| 6
| 11
| 3.009192
| 0.002619
|
P27544,O95470,P51648,O15121,Q96G23,O15269
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
96,162,71,267,79,213
|
267,213,1123,1525,162,1069,96,71,279,79,1159
|
1.3629484670588288,1.509227204047994,0.07708640378612587,-0.15616800678718376,1.8015665931551217,0.11977606936216245,2.2772978253938296,2.4964337739427047,1.305673915474619,2.40218638453676,0.06278501041697414
| 3,069
|
Sphingolipid metabolism
| 8
| 12
| 2.999262
| 0.002706
|
O95470,P06280,P04062,O15121,Q13510,P16278,Q06136,O15269
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
162,230,103,267,46,83,279,213
|
267,213,1123,497,162,103,230,83,279,46,306,1408
|
1.3629484670588288,1.509227204047994,0.07708640378612587,0.7625504930274744,1.8015665931551217,2.208903801378106,1.4534088423165563,2.37360689336414,1.305673915474619,2.9715906698002557,1.2128218563732212,-0.08224273671363029
| 3,069
|
Sterol binding
| 9
| 16
| 2.990395
| 0.002786
|
O15118,O75477,P35610,P21796,O94905,O95772,P30536,Q14108,P45880
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,286,291,41,265,45,114,63,31
|
192,286,265,45,770,41,1069,1601,114,291,31,63,784,1882,2914,325
|
1.6518518344930793,1.282602169065299,1.3743347259546723,2.9887720797510466,0.39646975457854383,3.182744358294726,0.11977606936216245,-0.2009891400311259,2.0796752385385897,1.2710312196614248,3.3623398601348073,2.5983448579795256,0.3829499709628327,-0.33761362784204135,-1.145304659012404,1.1776090170448037
| 3,069
|
Oxidoreductase complex
| 15
| 62
| 2.979233
| 0.00289
|
O43169,O14949,O14874,Q9Y6M9,Q86Y39,Q9P0J0,P07237,O43676,P21912,O96000,Q9UDW1,P13674,P03915,P31350,Q96CU9
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,32,448,260,293,74,172,16,176,208,19,396,273,315,160
|
1471,2596,1351,448,32,0,1064,16,1568,1164,1521,1144,2084,922,478,1802,208,2141,967,273,2483,172,1179,887,1225,1737,1282,2355,1283,396,1528,1494,1415,176,1089,1895,2536,2768,1388,315,732,2114,2246,988,1046,2148,1992,1310,2181,543,1111,2389,1425,293,2524,3048,160,74,19,799,810,260
|
-0.12648242619790095,-0.7683892185340218,-0.06757235345286404,0.8753931646747174,3.3301014796516952,3.832785549048474,0.11977606936216245,3.590805302191555,-0.18600945144458284,0.04844756194118684,-0.15616800678718376,0.06278501041697414,-0.446196376754283,0.24595582673959437,0.8129788391133055,-0.3069674436057677,1.5314026455401484,-0.47760517435342253,0.2042060940190475,1.317174902542949,-0.6861102721985591,1.7804174649941509,0.03407387466120978,0.2736197563045998,0.005217041828054251,-0.2764856883853633,-0.023786986148872924,-0.6050071745182394,-0.023786986148872924,0.9738559787002006,-0.15616800678718376,-0.14130583611076566,-0.09695107734044302,1.748546271130567,0.10558175302512113,-0.35299894149661604,-0.718878830028884,-0.9195667969445095,-0.08224273671363029,1.1893707968069043,0.4502300599193025,-0.4618790605702103,-0.5409488224408237,0.19022115610960058,0.13393505155524324,-0.47760517435342253,-0.39940650424205115,-0.03834467281593642,-0.4933749612214743,0.6988808910665117,0.0913519243495543,-0.6211353495660349,-0.09695107734044302,1.259436758440911,-0.702470899477358,-2.2359361102244577,1.8226377360704582,2.4870785513620435,3.505212800461361,0.3693979985962563,0.3558136826238937,1.397039326426985
| 3,069
|
Abnormal cellular phenotype
| 46
| 186
| 2.977476
| 0.002906
|
Q15904,Q9Y2R0,O60566,Q9Y6M9,P00403,Q9BUB7,O43676,Q14739,P00846,O75503,P03915,O60220,P09601,P07602,Q96CU9,Q9UBX3,Q9GZY8,Q86Y39,Q9UMS0,Q9Y584,Q13510,O75844,P21912,O14773,Q70HW3,P13073,Q14108,Q4J6C6,P15586,P20674,Q9P0J0,Q16134,P21964,Q9NZJ7,P28070,O96000,Q99496,P12235,Q16836,P04062,P23786,P35637,Q7KZN9,Q9NPL8,Q8N183,O75880
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
514,9,506,260,141,401,16,272,18,146,273,406,26,28,160,30,412,293,299,44,46,48,176,53,54,440,63,324,320,200,74,458,204,205,334,208,476,344,376,103,231,232,245,252,516,246
|
3042,2872,1471,2596,1517,2639,1351,2847,53,16,1568,594,406,506,1859,1521,1144,2084,922,146,48,246,1802,1441,2376,208,141,2899,1804,18,1356,604,273,103,985,28,1179,26,1225,1737,3052,2142,1282,2111,2599,344,2988,440,1528,2686,320,3020,1414,1227,1683,1415,1495,200,1570,2902,176,204,2688,231,2245,2876,2728,334,2768,1808,2361,2515,1388,1603,232,1253,2246,2064,1045,1531,2146,1742,1497,1416,2148,1308,1475,1309,2176,3024,1310,2149,1499,2517,1661,2491,991,753,2313,2838,2278,1171,992,1367,1748,1312,46,973,1689,63,272,2715,945,1291,2094,514,458,2389,376,710,910,324,1639,1054,1374,1671,2390,54,245,2548,2391,293,1375,516,1236,1850,2569,1874,2549,2073,526,773,2260,1460,1023,160,664,856,1560,2981,2962,1793,476,2722,1698,1296,401,1080,412,857,2321,726,252,2477,1795,2323,205,1565,74,2479,30,1383,1008,299,3028,1348,9,1010,810,1410,2267,1028,44,1984,1277,260
|
-2.004463803227854,-1.0748847085777697,-0.12648242619790095,-0.7683892185340218,-0.15616800678718376,-0.8016377952947211,-0.06757235345286404,-1.0226379236492988,2.858638405195539,3.590805302191555,-0.18600945144458284,0.6344916702788778,0.9616407296721227,0.7498733649115101,-0.33761362784204135,-0.15616800678718376,0.06278501041697414,-0.446196376754283,0.24595582673959437,1.874978181937071,2.9457216164408178,1.4196539730392503,-0.3069674436057677,-0.11169757381838322,-0.6211353495660349,1.5314026455401484,1.90615390951366,-1.127617485810929,-0.3069674436057677,3.536485172574649,-0.06757235345286404,0.6085307928083136,1.317174902542949,2.208903801378106,0.19022115610960058,3.418324905107978,0.03407387466120978,3.450072877013566,0.005217041828054251,-0.2764856883853633,-2.7294357611225606,-0.47760517435342253,-0.023786986148872924,-0.4618790605702103,-0.7683892185340218,1.1184335679045274,-1.398902708781335,0.8877944286969826,-0.15616800678718376,-0.8518788914948365,1.1776090170448037,-1.6256922666307558,-0.09695107734044302,0.005217041828054251,-0.2461665934751816,-0.09695107734044302,-0.14130583611076566,1.608345479738206,-0.18600945144458284,-1.127617485810929,1.748546271130567,1.5864673909793765,-0.8518788914948365,1.4534088423165563,-0.5409488224408237,-1.0748847085777697,-0.885621875365509,1.1421774665018345,-0.9195667969445095,-0.3069674436057677,-0.6050071745182394,-0.702470899477358,-0.08224273671363029,-0.2009891400311259,1.4534088423165563,-0.009266478234315357,-0.5409488224408237,-0.4305568818174603,0.13393505155524324,-0.15616800678718376,-0.47760517435342253,-0.2764856883853633,-0.14130583611076566,-0.09695107734044302,-0.47760517435342253,-0.03834467281593642,-0.12648242619790095,-0.03834467281593642,-0.4933749612214743,-1.6838381886675047,-0.03834467281593642,-0.47760517435342253,-0.14130583611076566,-0.702470899477358,-0.23106749871412027,-0.6861102721985591,0.19022115610960058,0.4234133694254319,-0.5728876459442109,-1.0053287737997052,-0.5568957742270876,0.04844756194118684,0.19022115610960058,-0.06757235345286404,-0.2764856883853633,-0.03834467281593642,2.9715906698002557,0.2042060940190475,-0.2461665934751816,2.5983448579795256,1.3286527579296776,-0.8687252926726254,0.23207326087768618,-0.023786986148872924,-0.446196376754283,0.7498733649115101,0.8629648599038147,-0.6211353495660349,1.0224569394488752,0.47692102554906757,0.25980460342637235,1.1776090170448037,-0.21600841862746054,0.13393505155524324,-0.06757235345286404,-0.23106749871412027,-0.6211353495660349,2.8410618513115837,1.430927787579856,-0.718878830028884,-0.6211353495660349,1.259436758440911,-0.06757235345286404,0.7498733649115101,0.005217041828054251,-0.3222698704241627,-0.7353343403528879,-0.33761362784204135,-0.718878830028884,-0.4305568818174603,0.7244341762651175,0.39646975457854383,-0.5409488224408237,-0.11169757381838322,0.16214771959355356,1.8226377360704582,0.5299304956557244,0.31486510761236025,-0.17106914307245863,-1.34359653403239,-1.2888250976967754,-0.29170612358688064,0.8255165059800994,-0.8687252926726254,-0.2461665934751816,-0.023786986148872924,0.9738559787002006,0.11977606936216245,0.9493992521351239,0.31486510761236025,-0.5728876459442109,0.46359118404072686,1.4196539730392503,-0.6697966741024561,-0.29170612358688064,-0.5728876459442109,1.5754968368419882,-0.17106914307245863,2.4870785513620435,-0.6697966741024561,3.3943981532933445,-0.06757235345286404,0.17620175517461098,1.236176913945832,-1.7229366897318243,-0.052939730621627525,3.832785549048474,0.17620175517461098,0.3558136826238937,-0.08224273671363029,-0.5409488224408237,0.16214771959355356,3.090793151825162,-0.38389514937413705,-0.009266478234315357,1.397039326426985
| 3,069
|
Establishment of protein localization to organelle
| 60
| 181
| 2.977127
| 0.00291
|
Q9NS69,O60830,Q99595,P62072,Q9Y5Y5,O96008,Q8N4H5,Q9HD47,Q96P70,O60220,P49458,Q9UHB9,Q9GZY8,Q99623,Q5THJ4,Q8N1F7,P52789,O14925,P55786,Q7Z4Q2,P49257,Q9Y584,P40855,O43615,Q15629,P56589,Q8WWC4,Q8N4Q1,O14737,Q15070,Q14108,O00459,O75381,P13473,Q15005,Q9P0J0,Q92783,Q8NFH5,P52292,Q99496,Q5JRX3,Q9NPF5,P51572,Q8N8Q8,Q9Y5M8,P30419,Q10713,Q99523,P61026,O75312,O00165,P78371,Q9Y512,Q92973,O43681,P30536,P46379,Q9Y5J9,Q9BRG1,Q99442
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
7,1,5,3,404,648,14,15,665,406,658,282,412,547,545,677,163,38,297,170,167,44,300,432,50,435,184,313,186,190,63,572,319,441,457,74,588,336,586,476,214,610,351,353,99,605,226,621,484,612,490,615,633,495,497,114,512,254,637,380
|
2169,490,702,2872,1653,572,1679,1597,2885,186,38,846,827,432,497,1203,406,1221,1,2643,612,2833,319,1145,1280,2781,952,2952,906,1178,2848,2017,1770,648,1356,985,865,729,1043,2302,2964,2795,2407,740,830,1710,441,2623,2087,1251,2727,987,2902,2357,605,114,882,2646,1284,2488,1207,2628,2064,300,512,1574,167,2308,658,2121,1809,1718,2275,2516,1417,351,586,1686,163,1047,1451,1605,297,435,1108,1575,1663,2492,484,2122,1333,3,1420,2464,2440,615,1171,720,226,1748,1312,2203,63,2387,1906,1289,457,2859,190,50,2258,819,2868,710,833,214,1938,545,2869,821,1264,1055,170,2936,677,14,313,353,336,692,2128,1099,184,588,495,665,2909,380,476,621,785,2572,5,547,825,1078,962,637,1269,2423,412,1619,1406,15,610,7,1623,2397,74,2854,1466,1624,2970,681,282,2101,2931,787,1274,2575,2370,1384,799,1349,860,633,44,254,1984,99,404
|
-0.4933749612214743,0.7878204493186719,0.47692102554906757,-1.0748847085777697,-0.23106749871412027,0.6603347615792099,-0.2461665934751816,-0.2009891400311259,-1.0924078528835213,1.6950293204096691,3.207568222440519,0.31486510761236025,0.3285473948164417,0.9001687703022228,0.7625504930274744,0.01966376346831093,0.9616407296721227,0.005217041828054251,3.832785549048474,-0.8016377952947211,0.5955058451096693,-1.0053287737997052,1.1776090170448037,0.06278501041697414,-0.023786986148872924,-0.9366157485523138,0.21815673924788037,-1.2706849905550104,0.25980460342637235,0.03407387466120978,-1.0226379236492988,-0.4149603366787841,-0.29170612358688064,0.5431061127497685,-0.06757235345286404,0.19022115610960058,0.30114984604267064,0.4502300599193025,0.13393505155524324,-0.5728876459442109,-1.30702347104922,-0.9537161071859821,-0.637309480977452,0.43683750484696116,0.3285473948164417,-0.26130591781680096,0.8877944286969826,-0.7849891516950118,-0.446196376754283,-0.009266478234315357,-0.885621875365509,0.19022115610960058,-1.127617485810929,-0.6050071745182394,0.6085307928083136,2.0796752385385897,0.28740144952661106,-0.8016377952947211,-0.023786986148872924,-0.6861102721985591,0.01966376346831093,-0.7849891516950118,-0.4305568818174603,1.2245113358720499,0.7498733649115101,-0.18600945144458284,1.791001813576259,-0.5728876459442109,0.5299304956557244,-0.4618790605702103,-0.3069674436057677,-0.26130591781680096,-0.5568957742270876,-0.702470899477358,-0.09695107734044302,1.0945904112546285,0.6474278718372324,-0.2461665934751816,1.8015665931551217,0.13393505155524324,-0.11169757381838322,-0.2009891400311259,1.2478186889019522,0.9001687703022228,0.0913519243495543,-0.18600945144458284,-0.23106749871412027,-0.6861102721985591,0.8004135279398286,-0.4618790605702103,-0.052939730621627525,3.832785549048474,-0.09695107734044302,-0.6697966741024561,-0.6535298334803012,0.5955058451096693,0.04844756194118684,0.46359118404072686,1.4758017160295607,-0.2764856883853633,-0.03834467281593642,-0.5091886663448594,2.5983448579795256,-0.6211353495660349,-0.35299894149661604,-0.023786986148872924,0.8629648599038147,-1.0400000767620767,1.6626768412225865,2.9110469379253097,-0.5409488224408237,0.34219686706793473,-1.057415561321741,0.47692102554906757,0.3285473948164417,1.509227204047994,-0.3684260388829964,0.6988808910665117,-1.057415561321741,0.34219686706793473,-0.009266478234315357,0.13393505155524324,1.791001813576259,-1.1986997815834857,0.5167243220793968,3.621616220862201,1.2011083765302808,1.0826313490872514,1.1421774665018345,0.5034874488366304,-0.4618790605702103,0.10558175302512113,1.716496296000973,0.6474278718372324,0.7878204493186719,0.5299304956557244,-1.127617485810929,1.0103454814086226,0.8255165059800994,0.5955058451096693,0.3829499709628327,-0.7353343403528879,3.832785549048474,0.6988808910665117,0.34219686706793473,0.11977606936216245,0.21815673924788037,0.5693662452264238,-0.009266478234315357,-0.637309480977452,0.9493992521351239,-0.2009891400311259,-0.08224273671363029,3.598523543210219,0.6085307928083136,3.832785549048474,-0.2009891400311259,-0.6211353495660349,2.4870785513620435,-1.0226379236492988,-0.11169757381838322,-0.2009891400311259,-1.30702347104922,0.5167243220793968,1.305673915474619,-0.446196376754283,-1.1808454547556477,0.3829499709628327,-0.009266478234315357,-0.7353343403528879,-0.6050071745182394,-0.06757235345286404,0.3693979985962563,-0.052939730621627525,0.31486510761236025,0.5824510420045746,3.090793151825162,1.4196539730392503,-0.38389514937413705,2.248086156847928,0.9738559787002006
| 3,069
|
Electron transport chain
| 18
| 68
| 2.971408
| 0.002964
|
O14949,Q9Y6M9,P04062,P20674,Q9P0J0,O15121,Q16134,P00403,Q9H3K2,O15460,O43676,P21912,O96000,Q9UDW1,Q7KZN9,P03915,P16435,P13073
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,260,103,200,74,267,458,141,332,426,16,176,208,19,245,273,154,440
|
1471,1351,32,267,426,749,2873,1064,16,1568,581,1164,1521,1144,2084,922,815,478,1802,208,2644,141,273,103,2963,2109,865,887,2303,1225,1226,1988,440,1528,2019,1494,2485,1772,154,1415,200,176,2022,1895,2768,1388,2246,988,1046,2028,2148,1310,1421,1813,1750,458,1111,2389,977,245,2504,2942,332,74,19,1383,810,260
|
-0.12648242619790095,-0.06757235345286404,3.3301014796516952,1.3629484670588288,0.912516307045338,0.4234133694254319,-1.0748847085777697,0.11977606936216245,3.590805302191555,-0.18600945144458284,0.6474278718372324,0.04844756194118684,-0.15616800678718376,0.06278501041697414,-0.446196376754283,0.24595582673959437,0.34219686706793473,0.8129788391133055,-0.3069674436057677,1.5314026455401484,-0.8016377952947211,1.90615390951366,1.317174902542949,2.208903801378106,-1.30702347104922,-0.4618790605702103,0.30114984604267064,0.2736197563045998,-0.5728876459442109,0.005217041828054251,0.005217041828054251,-0.39940650424205115,0.8877944286969826,-0.15616800678718376,-0.4149603366787841,-0.14130583611076566,-0.6861102721985591,-0.29170612358688064,1.843631471229452,-0.09695107734044302,1.608345479738206,1.748546271130567,-0.4149603366787841,-0.35299894149661604,-0.9195667969445095,-0.08224273671363029,-0.5409488224408237,0.19022115610960058,0.13393505155524324,-0.4149603366787841,-0.47760517435342253,-0.03834467281593642,-0.09695107734044302,-0.3069674436057677,-0.2764856883853633,0.8629648599038147,0.0913519243495543,-0.6211353495660349,0.2042060940190475,1.430927787579856,-0.6861102721985591,-1.2166105361942672,1.1540124536294423,2.4870785513620435,3.505212800461361,-0.06757235345286404,0.3558136826238937,1.397039326426985
| 3,069
|
Serine hydrolase activity
| 8
| 17
| 2.963102
| 0.003046
|
Q9HB40,Q16740,P67812,Q9H3G5,O14773,Q5JRX3,P10619,P42785
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
6,234,211,212,53,214,25,59
|
53,530,25,1711,2361,1331,59,2147,1047,2337,211,234,324,214,1056,212,6
|
2.858638405195539,0.7116718601694995,3.4579825093765058,-0.26130591781680096,-0.6050071745182394,-0.052939730621627525,2.7074905411166843,-0.47760517435342253,0.13393505155524324,-0.5889246933797637,1.5203256899968731,1.4534088423165563,1.1776090170448037,1.509227204047994,0.13393505155524324,1.5203256899968731,3.832785549048474
| 3,069
|
Abnormality of hepatobiliary system physiology
| 26
| 77
| 2.948814
| 0.00319
|
P35670,Q9Y619,Q9Y5Y5,P00846,Q96A33,P03915,Q8N511,P38571,Q16625,P40855,Q13510,O15460,P56589,Q9P2J5,O75381,O15118,P39210,Q5XKP0,P22830,Q6NUQ1,Q10713,P04062,P23786,P46100,Q9BT22,Q16836
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
257,130,404,18,149,273,27,416,165,300,46,426,435,444,319,192,453,198,202,474,226,103,231,354,362,376
|
2013,192,426,594,581,2643,1144,319,2376,18,954,273,103,1657,1473,887,1225,2111,1089,202,231,1090,1861,257,1253,2115,416,453,1716,300,1045,2966,2146,354,500,2249,2463,2812,2661,435,2466,991,1210,226,1748,46,1637,1723,165,762,376,198,474,2390,1849,27,563,2569,149,2095,1560,1793,362,1296,2321,3001,2574,1981,444,2553,2855,799,1299,1410,1984,404,130
|
-0.4149603366787841,1.6518518344930793,0.912516307045338,0.6344916702788778,0.6474278718372324,-0.8016377952947211,0.06278501041697414,1.1776090170448037,-0.6211353495660349,3.536485172574649,0.21815673924788037,1.317174902542949,2.208903801378106,-0.23106749871412027,-0.12648242619790095,0.2736197563045998,0.005217041828054251,-0.4618790605702103,0.10558175302512113,1.5974169115678218,1.4534088423165563,0.10558175302512113,-0.33761362784204135,1.397039326426985,-0.009266478234315357,-0.4618790605702103,0.9371314323192231,0.8629648599038147,-0.26130591781680096,1.2245113358720499,0.13393505155524324,-1.30702347104922,-0.47760517435342253,1.0706471565843538,0.7625504930274744,-0.5409488224408237,-0.6697966741024561,-0.970868186256457,-0.8183354383139178,0.9001687703022228,-0.6697966741024561,0.19022115610960058,0.01966376346831093,1.4758017160295607,-0.2764856883853633,2.9715906698002557,-0.21600841862746054,-0.26130591781680096,1.8015665931551217,0.4099575031857863,1.0224569394488752,1.6192531761518294,0.8255165059800994,-0.6211353495660349,-0.3222698704241627,3.442152330866641,0.6732124730764801,-0.7353343403528879,1.8645483697136485,-0.446196376754283,-0.17106914307245863,-0.29170612358688064,1.0586377270711074,-0.023786986148872924,-0.5728876459442109,-1.4547542510082334,-0.7353343403528879,-0.38389514937413705,0.8877944286969826,-0.718878830028884,-1.0226379236492988,0.3693979985962563,-0.023786986148872924,-0.08224273671363029,-0.38389514937413705,0.9738559787002006,1.9884673871689231
| 3,069
|
Alzheimers disease
| 14
| 58
| 2.941466
| 0.003267
|
O14949,Q9Y6M9,Q92542,P20674,P00403,P16615,O43676,P21912,P00846,Q9UDW1,O96000,P14406,P13073,P24539
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
32,260,392,200,141,333,16,176,18,19,208,111,440,158
|
1471,1351,32,1064,16,1568,1521,1144,2084,922,1177,478,1802,208,141,18,2645,1129,2900,887,1328,2964,1226,440,111,1712,1494,1772,333,2513,1415,200,176,1089,158,2359,2306,2768,2062,1388,732,1044,1046,2824,1497,2148,1257,1310,909,720,2561,1111,2389,392,2722,19,2101,260
|
-0.12648242619790095,-0.06757235345286404,3.3301014796516952,0.11977606936216245,3.590805302191555,-0.18600945144458284,-0.15616800678718376,0.06278501041697414,-0.446196376754283,0.24595582673959437,0.03407387466120978,0.8129788391133055,-0.3069674436057677,1.5314026455401484,1.90615390951366,3.536485172574649,-0.8016377952947211,0.07708640378612587,-1.127617485810929,0.2736197563045998,-0.052939730621627525,-1.30702347104922,0.005217041828054251,0.8877944286969826,2.1097574181491536,-0.26130591781680096,-0.14130583611076566,-0.29170612358688064,1.1421774665018345,-0.702470899477358,-0.09695107734044302,1.608345479738206,1.748546271130567,0.10558175302512113,1.8226377360704582,-0.6050071745182394,-0.5728876459442109,-0.9195667969445095,-0.4305568818174603,-0.08224273671363029,0.4502300599193025,0.13393505155524324,0.13393505155524324,-0.9880723020572022,-0.14130583611076566,-0.47760517435342253,-0.009266478234315357,-0.03834467281593642,0.25980460342637235,0.46359118404072686,-0.7353343403528879,0.0913519243495543,-0.6211353495660349,0.9860451122520546,-0.8687252926726254,3.505212800461361,-0.446196376754283,1.397039326426985
| 3,069
|
Cholesterol binding
| 9
| 13
| 2.940844
| 0.003273
|
O15118,O75477,P35610,P21796,O94905,O95772,P30536,Q14108,P45880
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,286,291,41,265,45,114,63,31
|
192,286,265,45,770,41,1601,114,291,31,63,2914,325
|
1.6518518344930793,1.282602169065299,1.3743347259546723,2.9887720797510466,0.39646975457854383,3.182744358294726,-0.2009891400311259,2.0796752385385897,1.2710312196614248,3.3623398601348073,2.5983448579795256,-1.145304659012404,1.1776090170448037
| 3,069
|
Abnormality of the cerebrospinal fluid
| 39
| 143
| 2.937588
| 0.003308
|
O60566,Q9Y6M9,P08236,P00403,O43676,P00846,P03915,P16435,O43505,P07602,Q96CU9,Q8NAT1,Q16625,Q86Y39,Q9HC21,P07237,P40855,Q9C0B1,Q9NR77,P13073,P53701,Q15392,P39210,Q9P0J0,P21964,Q9NZJ7,O96000,Q99496,Q6NUK1,Q10713,P04062,P23786,P07942,P30153,O43681,Q7KZN9,Q9NPL8,Q8N183,O96028
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
506,260,522,141,16,18,273,154,411,28,160,288,165,293,425,172,300,181,185,440,65,194,453,74,204,205,208,476,220,226,103,231,491,371,497,245,252,516,247
|
3042,1471,2596,572,1351,2847,1654,2083,411,16,1568,497,581,506,1126,1521,1144,612,2084,922,847,2243,906,717,1802,1770,208,247,141,18,273,103,985,172,28,491,522,1179,877,3052,440,154,1227,1415,1495,1068,2902,2357,204,231,2876,2768,2515,371,1388,1715,1776,1254,1991,1331,453,300,2117,2146,707,2089,1809,2148,2176,3024,1310,1499,65,2517,1781,1901,2944,2383,2543,1261,2181,1631,895,1037,226,1632,3033,1367,1313,974,2635,2814,2715,194,1690,165,2389,1292,220,1314,245,1849,293,2036,516,1788,288,2895,898,835,1850,2569,1874,2073,2039,1428,526,1460,160,1057,1793,476,2722,1296,1080,181,2192,609,425,252,185,1795,2323,205,1565,74,1143,1649,1010,810,2053,1516,260
|
-2.004463803227854,-0.12648242619790095,-0.7683892185340218,0.6603347615792099,-0.06757235345286404,-1.0226379236492988,-0.23106749871412027,-0.446196376754283,0.9493992521351239,3.590805302191555,-0.18600945144458284,0.7625504930274744,0.6474278718372324,0.7498733649115101,0.07708640378612587,-0.15616800678718376,0.06278501041697414,0.5955058451096693,-0.446196376754283,0.24595582673959437,0.31486510761236025,-0.5409488224408237,0.25980460342637235,0.46359118404072686,-0.3069674436057677,-0.29170612358688064,1.5314026455401484,1.4196539730392503,1.90615390951366,3.536485172574649,1.317174902542949,2.208903801378106,0.19022115610960058,1.7804174649941509,3.418324905107978,0.7878204493186719,0.7244341762651175,0.03407387466120978,0.28740144952661106,-2.7294357611225606,0.8877944286969826,1.843631471229452,0.005217041828054251,-0.09695107734044302,-0.14130583611076566,0.11977606936216245,-1.127617485810929,-0.6050071745182394,1.5864673909793765,1.4534088423165563,-1.0748847085777697,-0.9195667969445095,-0.702470899477358,1.0345427268960783,-0.08224273671363029,-0.26130591781680096,-0.29170612358688064,-0.009266478234315357,-0.39940650424205115,-0.052939730621627525,0.8629648599038147,1.2245113358720499,-0.4618790605702103,-0.47760517435342253,0.47692102554906757,-0.446196376754283,-0.3069674436057677,-0.47760517435342253,-0.4933749612214743,-1.6838381886675047,-0.03834467281593642,-0.14130583611076566,2.570730314495249,-0.702470899477358,-0.29170612358688064,-0.35299894149661604,-1.2345780792276917,-0.6211353495660349,-0.718878830028884,-0.009266478234315357,-0.4933749612214743,-0.21600841862746054,0.2736197563045998,0.1480588764572703,1.4758017160295607,-0.21600841862746054,-1.841879764249894,-0.06757235345286404,-0.03834467281593642,0.2042060940190475,-0.7849891516950118,-0.970868186256457,-0.8687252926726254,1.6410062740261269,-0.2461665934751816,1.8015665931551217,-0.6211353495660349,-0.023786986148872924,1.4981071031700752,-0.03834467281593642,1.430927787579856,-0.3222698704241627,1.259436758440911,-0.4149603366787841,0.7498733649115101,-0.29170612358688064,1.282602169065299,-1.1099853317350328,0.2736197563045998,0.3285473948164417,-0.3222698704241627,-0.7353343403528879,-0.33761362784204135,-0.4305568818174603,-0.4149603366787841,-0.09695107734044302,0.7244341762651175,-0.11169757381838322,1.8226377360704582,0.13393505155524324,-0.29170612358688064,0.8255165059800994,-0.8687252926726254,-0.023786986148872924,0.11977606936216245,1.7378829103625977,-0.4933749612214743,0.6085307928083136,0.9248371557106364,1.4196539730392503,1.7057728913838957,-0.29170612358688064,-0.5728876459442109,1.5754968368419882,-0.17106914307245863,2.4870785513620435,0.07708640378612587,-0.21600841862746054,0.17620175517461098,0.3558136826238937,-0.4149603366787841,-0.14130583611076566,1.397039326426985
| 3,069
|
Myoclonus
| 26
| 90
| 2.936787
| 0.003316
|
P50897,P00403,Q969G3,P00846,O75503,P09471,P03915,P07602,Q96CU9,Q9UBX3,Q5THJ4,O14936,P00374,Q13510,O14773,P13073,Q14108,Q01105,Q9NZJ7,Q9Y4G8,Q99496,P27544,Q10713,Q6PJG6,P04062,Q9NPL8
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
2,141,526,18,146,395,273,28,160,30,545,548,43,46,53,440,63,327,205,466,476,96,226,356,103,252
|
1351,2846,2054,53,548,2641,146,1801,1165,1441,648,43,141,18,273,103,1836,28,2303,395,3052,440,1956,1713,1895,96,942,1839,1388,1284,1253,1207,2537,2199,2380,2148,1308,2,2176,1604,1499,1901,1000,1364,672,2467,327,895,1998,2066,720,226,1632,1367,46,1172,63,2999,2635,1112,545,1374,356,2391,2207,913,898,526,564,160,2500,856,1484,1644,2233,2613,2367,476,1296,1920,935,726,252,2324,205,30,1625,466,1028,2845
|
-0.06757235345286404,-1.0226379236492988,-0.4305568818174603,2.858638405195539,0.686061138987713,-0.8016377952947211,1.874978181937071,-0.3069674436057677,0.04844756194118684,-0.11169757381838322,0.5431061127497685,3.1076215791981863,1.90615390951366,3.536485172574649,1.317174902542949,2.208903801378106,-0.3222698704241627,3.418324905107978,-0.5728876459442109,0.9738559787002006,-2.7294357611225606,0.8877944286969826,-0.38389514937413705,-0.26130591781680096,-0.35299894149661604,2.2772978253938296,0.23207326087768618,-0.3222698704241627,-0.08224273671363029,-0.023786986148872924,-0.009266478234315357,0.01966376346831093,-0.718878830028884,-0.5091886663448594,-0.6211353495660349,-0.47760517435342253,-0.03834467281593642,3.832785549048474,-0.4933749612214743,-0.2009891400311259,-0.14130583611076566,-0.35299894149661604,0.17620175517461098,-0.06757235345286404,0.5167243220793968,-0.6697966741024561,1.1658229364583745,0.2736197563045998,-0.39940650424205115,-0.4305568818174603,0.46359118404072686,1.4758017160295607,-0.21600841862746054,-0.06757235345286404,2.9715906698002557,0.04844756194118684,2.5983448579795256,-1.4547542510082334,-0.7849891516950118,0.0913519243495543,0.6988808910665117,-0.06757235345286404,1.0706471565843538,-0.6211353495660349,-0.5091886663448594,0.25980460342637235,0.2736197563045998,0.7244341762651175,0.6732124730764801,1.8226377360704582,-0.6861102721985591,0.31486510761236025,-0.12648242619790095,-0.21600841862746054,-0.525046536969556,-0.7683892185340218,-0.6050071745182394,0.8255165059800994,-0.023786986148872924,-0.35299894149661604,0.24595582673959437,0.46359118404072686,1.4196539730392503,-0.5728876459442109,1.5754968368419882,3.3943981532933445,-0.2009891400311259,0.8505093952684031,0.16214771959355356,-1.0053287737997052
| 3,069
|
Organelle envelope lumen
| 15
| 39
| 2.932364
| 0.003364
|
Q9NR28,O60313,O14925,Q8N4Q1,Q96BR5,P62072,O00165,Q9HB71,Q16891,Q9BPX6,Q96AY3,Q9Y255,O60220,Q9Y5J9,O00584
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
121,414,38,313,330,3,490,311,467,468,150,88,406,254,191
|
490,191,38,406,414,1770,1893,1327,777,2513,2768,1449,684,1228,1310,2309,1661,3,1287,467,833,977,2230,546,313,2569,150,330,2504,468,638,1825,935,311,121,994,88,1122,254
|
0.7878204493186719,1.6518518344930793,3.207568222440519,0.9616407296721227,0.9371314323192231,-0.29170612358688064,-0.35299894149661604,-0.052939730621627525,0.3829499709628327,-0.702470899477358,-0.9195667969445095,-0.11169757381838322,0.5034874488366304,0.005217041828054251,-0.03834467281593642,-0.5728876459442109,-0.23106749871412027,3.832785549048474,-0.023786986148872924,0.838026650861996,0.3285473948164417,0.2042060940190475,-0.525046536969556,0.6988808910665117,1.2011083765302808,-0.7353343403528879,1.8645483697136485,1.1540124536294423,-0.6861102721985591,0.838026650861996,0.5693662452264238,-0.3069674436057677,0.24595582673959437,1.2128218563732212,2.05953218036522,0.19022115610960058,2.3352775446813796,0.0913519243495543,1.4196539730392503
| 3,069
|
Ceramide biosynthetic process
| 6
| 11
| 2.927741
| 0.003414
|
P27544,P04062,O15121,Q13510,Q96G23,O15269
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,103,267,46,79,213
|
267,213,1123,103,96,1171,46,306,833,79,1408
|
1.3629484670588288,1.509227204047994,0.07708640378612587,2.208903801378106,2.2772978253938296,0.04844756194118684,2.9715906698002557,1.2128218563732212,0.3285473948164417,2.40218638453676,-0.08224273671363029
| 3,069
|
Biliary tract abnormality
| 8
| 23
| 2.922855
| 0.003468
|
Q10713,Q5XKP0,P04062,Q9NZJ7,O96028,P09601,P07602,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
226,198,103,205,247,26,28,63
|
497,717,247,1356,103,28,26,2686,1570,1331,1230,226,1748,63,272,198,2946,1560,2574,205,1008,799,1984
|
0.7625504930274744,0.46359118404072686,1.4196539730392503,-0.06757235345286404,2.208903801378106,3.418324905107978,3.450072877013566,-0.8518788914948365,-0.18600945144458284,-0.052939730621627525,0.005217041828054251,1.4758017160295607,-0.2764856883853633,2.5983448579795256,1.3286527579296776,1.6192531761518294,-1.2345780792276917,-0.17106914307245863,-0.7353343403528879,1.5754968368419882,0.17620175517461098,0.3693979985962563,-0.38389514937413705
| 3,069
|
Visual loss
| 15
| 50
| 2.921923
| 0.003479
|
P53701,O60313,Q10713,P50897,P00403,Q9NZJ7,O15460,P04439,O75503,P00846,P03915,O14773,Q99496,O60220,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,414,226,2,141,205,426,498,146,18,273,53,476,406,28
|
2013,2215,702,1517,53,426,406,414,1144,1145,146,2579,906,141,2766,18,954,273,1681,498,28,2834,2996,1683,2357,2305,942,1776,1254,1045,1359,2,1230,3024,1149,65,1261,226,1632,1367,1395,1313,2715,1482,823,526,476,2722,726,205
|
-0.4149603366787841,-0.525046536969556,0.47692102554906757,-0.15616800678718376,2.858638405195539,0.912516307045338,0.9616407296721227,0.9371314323192231,0.06278501041697414,0.06278501041697414,1.874978181937071,-0.7518377093865654,0.25980460342637235,1.90615390951366,-0.9195667969445095,3.536485172574649,0.21815673924788037,1.317174902542949,-0.2461665934751816,0.7625504930274744,3.418324905107978,-1.0053287737997052,-1.436075804697021,-0.2461665934751816,-0.6050071745182394,-0.5728876459442109,0.23207326087768618,-0.29170612358688064,-0.009266478234315357,0.13393505155524324,-0.06757235345286404,3.832785549048474,0.005217041828054251,-1.6838381886675047,0.06278501041697414,2.570730314495249,-0.009266478234315357,1.4758017160295607,-0.21600841862746054,-0.06757235345286404,-0.08224273671363029,-0.03834467281593642,-0.8687252926726254,-0.12648242619790095,0.34219686706793473,0.7244341762651175,0.8255165059800994,-0.8687252926726254,0.46359118404072686,1.5754968368419882
| 3,069
|
Muscle weakness
| 78
| 292
| 2.915001
| 0.003557
|
P05023,Q969G3,O43676,P00846,Q15043,P07602,Q5THJ4,O14936,Q9UHX1,P00374,Q13510,Q70HW3,Q9P0J0,Q9BQT8,Q6DKK2,Q9NWM8,Q13126,P17900,P51114,P00403,Q96CU9,P21912,Q92804,Q9NR77,P10253,Q5XKP0,Q9NZJ7,O96000,O15269,Q6NUK1,Q10713,P23786,P35637,P50402,Q9NPL8,P35670,Q9Y6M9,P07196,O94905,O14979,Q14739,P03915,Q9BTV4,Q8NAT1,Q86Y39,Q9UMS0,P40855,P06865,Q99720,O75381,Q15067,Q4J6C6,Q96BR5,O00400,P12235,Q13586,P41440,P50995,Q9Y5Y5,O75298,P09471,O43505,Q9GZY8,O60313,Q9HC21,P22626,O15460,P56589,Q15165,P13073,P13473,P39210,P61978,Q16134,Q9BPX6,Q99496,O43681,Q8N183
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
509,526,16,18,533,28,545,548,36,43,46,54,74,95,100,108,109,123,137,141,160,176,178,185,193,198,205,208,213,220,226,231,232,237,252,257,260,261,265,271,272,273,284,288,293,299,300,303,314,319,323,324,330,328,344,364,379,390,404,394,395,411,412,414,425,427,426,435,436,440,441,453,455,458,468,476,497,516
|
2215,1471,328,2846,2885,1654,548,271,213,1123,426,411,16,497,594,581,2744,414,1986,1859,1521,394,1144,2454,2084,319,1145,922,265,906,1525,1802,1165,2055,829,2017,1770,208,43,141,2766,18,954,1356,273,2705,1681,985,939,509,2301,1657,1357,303,261,2900,28,1104,1167,2197,2532,395,940,193,877,2795,2111,1894,344,440,441,1528,771,2486,2782,123,1251,1415,1068,2357,176,2835,427,2459,231,2768,942,1388,2025,1070,1840,2710,2435,2959,232,257,1991,684,2627,1207,2246,2537,453,2064,300,2117,1045,2436,379,2146,2199,2660,969,1742,1046,707,2380,2381,1416,1809,2148,1228,237,926,390,137,1417,1309,2176,1994,3024,892,1310,2149,1450,1499,851,2223,2540,1362,2491,2463,1901,2661,435,1168,2749,455,1000,1184,2467,3040,1393,1998,2066,2544,2784,2631,992,720,226,1632,3033,1367,109,1312,1313,46,364,1424,2340,974,1815,2999,2546,1212,2069,272,2815,533,2715,323,2416,1750,436,780,1786,458,553,2860,710,324,833,1019,871,1152,1292,1054,626,545,854,198,100,978,220,2667,1314,763,54,2719,2548,1481,293,2991,516,1506,288,1726,691,898,692,1850,2569,1154,1458,2320,1238,823,1193,178,2946,2979,526,1005,330,160,745,1484,1644,1057,2367,1561,476,2722,314,2591,468,1698,95,284,1727,1296,982,767,2291,2700,412,1920,644,2321,425,252,1622,185,826,108,205,1565,74,3023,2479,809,2010,2101,1763,36,299,3028,1855,799,2051,1348,1950,810,579,1028,1984,1516,404,1161,260,2168
|
-0.525046536969556,-0.12648242619790095,1.1540124536294423,-1.0226379236492988,-1.0924078528835213,-0.23106749871412027,0.686061138987713,1.3286527579296776,1.509227204047994,0.07708640378612587,0.912516307045338,0.9493992521351239,3.590805302191555,0.7625504930274744,0.6344916702788778,0.6474278718372324,-0.9025689417990336,0.9371314323192231,-0.39940650424205115,-0.33761362784204135,-0.15616800678718376,0.9738559787002006,0.06278501041697414,-0.6697966741024561,-0.446196376754283,1.1776090170448037,0.06278501041697414,0.24595582673959437,1.3743347259546723,0.25980460342637235,-0.15616800678718376,-0.3069674436057677,0.04844756194118684,-0.4305568818174603,0.3285473948164417,-0.4149603366787841,-0.29170612358688064,1.5314026455401484,3.1076215791981863,1.90615390951366,-0.9195667969445095,3.536485172574649,0.21815673924788037,-0.06757235345286404,1.317174902542949,-0.8687252926726254,-0.2461665934751816,0.19022115610960058,0.23207326087768618,0.7498733649115101,-0.5728876459442109,-0.23106749871412027,-0.06757235345286404,1.2128218563732212,1.3856983154795637,-1.127617485810929,3.418324905107978,0.0913519243495543,0.04844756194118684,-0.5091886663448594,-0.718878830028884,0.9738559787002006,0.23207326087768618,1.6518518344930793,0.28740144952661106,-0.9537161071859821,-0.4618790605702103,-0.35299894149661604,1.1184335679045274,0.8877944286969826,0.8877944286969826,-0.15616800678718376,0.39646975457854383,-0.6861102721985591,-0.9366157485523138,2.039317917817865,-0.009266478234315357,-0.09695107734044302,0.11977606936216245,-0.6050071745182394,1.748546271130567,-1.0053287737997052,0.912516307045338,-0.6697966741024561,1.4534088423165563,-0.9195667969445095,0.23207326087768618,-0.08224273671363029,-0.4149603366787841,0.11977606936216245,-0.3222698704241627,-0.8687252926726254,-0.6535298334803012,-1.2888250976967754,1.4534088423165563,1.397039326426985,-0.39940650424205115,0.5034874488366304,-0.7849891516950118,0.01966376346831093,-0.5409488224408237,-0.718878830028884,0.8629648599038147,-0.4305568818174603,1.2245113358720499,-0.4618790605702103,0.13393505155524324,-0.6535298334803012,1.0103454814086226,-0.47760517435342253,-0.5091886663448594,-0.8183354383139178,0.2042060940190475,-0.2764856883853633,0.13393505155524324,0.47692102554906757,-0.6211353495660349,-0.6211353495660349,-0.09695107734044302,-0.3069674436057677,-0.47760517435342253,0.005217041828054251,1.4421793813029162,0.24595582673959437,0.9860451122520546,1.9371605235671987,-0.09695107734044302,-0.03834467281593642,-0.4933749612214743,-0.39940650424205115,-1.6838381886675047,0.2736197563045998,-0.03834467281593642,-0.47760517435342253,-0.11169757381838322,-0.14130583611076566,0.31486510761236025,-0.525046536969556,-0.718878830028884,-0.06757235345286404,-0.6861102721985591,-0.6697966741024561,-0.35299894149661604,-0.8183354383139178,0.9001687703022228,0.04844756194118684,-0.9025689417990336,0.8629648599038147,0.17620175517461098,0.03407387466120978,-0.6697966741024561,-1.9838833450363904,-0.08224273671363029,-0.39940650424205115,-0.4305568818174603,-0.718878830028884,-0.9366157485523138,-0.7849891516950118,0.19022115610960058,0.46359118404072686,1.4758017160295607,-0.21600841862746054,-1.841879764249894,-0.06757235345286404,2.1297246577528743,-0.03834467281593642,-0.03834467281593642,2.9715906698002557,1.0466029531902257,-0.09695107734044302,-0.5889246933797637,0.2042060940190475,-0.3069674436057677,-1.4547542510082334,-0.718878830028884,0.01966376346831093,-0.4305568818174603,1.3286527579296776,-0.970868186256457,0.7116718601694995,-0.8687252926726254,1.1776090170448037,-0.637309480977452,-0.2764856883853633,0.9001687703022228,0.3829499709628327,-0.29170612358688064,0.8629648599038147,0.686061138987713,-1.0400000767620767,0.47692102554906757,1.1776090170448037,0.3285473948164417,0.16214771959355356,0.30114984604267064,0.06278501041697414,-0.023786986148872924,0.13393505155524324,0.5824510420045746,0.6988808910665117,0.31486510761236025,1.6192531761518294,2.2383156968635576,0.2042060940190475,1.4981071031700752,-0.8183354383139178,-0.03834467281593642,0.4099575031857863,2.8410618513115837,-0.8687252926726254,-0.718878830028884,-0.12648242619790095,1.259436758440911,-1.398902708781335,0.7498733649115101,-0.14130583611076566,1.282602169065299,-0.26130591781680096,0.5034874488366304,0.2736197563045998,0.5034874488366304,-0.3222698704241627,-0.7353343403528879,0.06278501041697414,-0.11169757381838322,-0.5728876459442109,0.005217041828054251,0.34219686706793473,0.03407387466120978,1.748546271130567,-1.2345780792276917,-1.34359653403239,0.7244341762651175,0.17620175517461098,1.1540124536294423,1.8226377360704582,0.43683750484696116,-0.12648242619790095,-0.21600841862746054,0.13393505155524324,-0.6050071745182394,-0.17106914307245863,0.8255165059800994,-0.8687252926726254,1.2011083765302808,-0.7518377093865654,0.838026650861996,-0.2461665934751816,2.287002000595034,1.2941497025621402,-0.26130591781680096,-0.023786986148872924,0.2042060940190475,0.4099575031857863,-0.5568957742270876,-0.8518788914948365,0.9493992521351239,-0.35299894149661604,0.5562513155435278,-0.5728876459442109,0.9248371557106364,1.4196539730392503,-0.2009891400311259,1.7057728913838957,0.34219686706793473,2.1694512293067545,1.5754968368419882,-0.17106914307245863,2.4870785513620435,-1.6450079456876248,-0.6697966741024561,0.3558136826238937,-0.39940650424205115,-0.446196376754283,-0.2764856883853633,3.240500487670887,1.236176913945832,-1.7229366897318243,-0.3222698704241627,0.3693979985962563,-0.4149603366787841,-0.052939730621627525,-0.3684260388829964,0.3558136826238937,0.6603347615792099,0.16214771959355356,-0.38389514937413705,-0.14130583611076566,0.9738559787002006,0.06278501041697414,1.397039326426985,-0.47760517435342253
| 3,069
|
Liposaccharide metabolic process
| 7
| 16
| 2.913441
| 0.003575
|
Q8NBX0,P06280,P04062,Q99805,P16278,P06865,P17900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
224,230,103,298,83,303,123
|
622,1204,103,1033,230,303,1104,83,123,1171,306,224,773,1266,298,609
|
0.5824510420045746,0.01966376346831093,2.208903801378106,0.1480588764572703,1.4534088423165563,1.2128218563732212,0.0913519243495543,2.37360689336414,2.039317917817865,0.04844756194118684,1.2128218563732212,1.4869653023397031,0.39646975457854383,-0.009266478234315357,1.236176913945832,0.6085307928083136
| 3,069
|
Abnormal circulating cholesterol concentration
| 13
| 29
| 2.912741
| 0.003583
|
Q15904,Q15800,Q15392,Q9NZJ7,Q9NVI7,Q14739,Q9BTV4,P37268,P50402,Q13045,Q8N511,P07602,P38571
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
514,66,194,205,367,272,284,433,237,275,27,28,416
|
1065,1356,2110,28,943,433,416,2199,1574,237,2811,1108,552,275,2340,272,194,1969,66,514,27,1238,284,3001,367,205,1143,1383,1301
|
0.11977606936216245,-0.06757235345286404,-0.4618790605702103,3.418324905107978,0.23207326087768618,0.9001687703022228,0.9371314323192231,-0.5091886663448594,-0.18600945144458284,1.4421793813029162,-0.970868186256457,0.0913519243495543,0.686061138987713,1.317174902542949,-0.5889246933797637,1.3286527579296776,1.6410062740261269,-0.38389514937413705,2.5522463606903325,0.7498733649115101,3.442152330866641,0.005217041828054251,1.2941497025621402,-1.4547542510082334,1.0466029531902257,1.5754968368419882,0.07708640378612587,-0.06757235345286404,-0.023786986148872924
| 3,069
|
Cardiac muscle contraction
| 7
| 20
| 2.907696
| 0.003641
|
O14949,P20674,P00403,P16615,P14406,Q9UDW1,P13073
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
32,200,141,333,111,19,440
|
32,141,509,1042,1357,887,1328,1226,440,111,1494,1772,333,200,1089,732,1046,1866,1095,19
|
3.3301014796516952,1.90615390951366,0.7498733649115101,0.13393505155524324,-0.06757235345286404,0.2736197563045998,-0.052939730621627525,0.005217041828054251,0.8877944286969826,2.1097574181491536,-0.14130583611076566,-0.29170612358688064,1.1421774665018345,1.608345479738206,0.10558175302512113,0.4502300599193025,0.13393505155524324,-0.33761362784204135,0.10558175302512113,3.505212800461361
| 3,069
|
Regulation of mitochondrion organization
| 18
| 43
| 2.903608
| 0.003689
|
P27544,O60313,Q9Y6C9,P30419,P02786,P21796,Q9H3K2,O00165,Q9NUQ9,Q9NQ88,Q9UG56,Q96A26,P30536,Q9Y255,P12235,O14737,Q9GZY8,Q5THJ4
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
96,414,259,605,604,41,332,490,175,592,145,92,114,88,344,186,412,545
|
490,1517,186,414,1205,1356,604,985,816,740,344,2727,41,96,1958,605,114,2118,2199,1718,1257,975,2860,545,2936,1115,1400,793,92,1216,2262,2504,630,412,332,592,1006,175,1466,145,787,88,259
|
0.7878204493186719,-0.15616800678718376,1.6950293204096691,0.9371314323192231,0.01966376346831093,-0.06757235345286404,0.6085307928083136,0.19022115610960058,0.34219686706793473,0.43683750484696116,1.1184335679045274,-0.885621875365509,3.182744358294726,2.2772978253938296,-0.38389514937413705,0.6085307928083136,2.0796752385385897,-0.4618790605702103,-0.5091886663448594,-0.26130591781680096,-0.009266478234315357,0.2042060940190475,-1.0400000767620767,0.6988808910665117,-1.1986997815834857,0.0913519243495543,-0.08224273671363029,0.3693979985962563,2.2966897459870523,0.01966376346831093,-0.5409488224408237,-0.6861102721985591,0.5824510420045746,0.9493992521351239,1.1540124536294423,0.6474278718372324,0.17620175517461098,1.7698134742055545,-0.11169757381838322,1.8853889962920538,0.3829499709628327,2.3352775446813796,1.397039326426985
| 3,069
|
Progressive neurologic deterioration
| 8
| 20
| 2.901712
| 0.003711
|
Q10713,Q5XKP0,P04062,Q9NZJ7,P21912,P54802,P16278,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
226,198,103,205,176,177,83,28
|
497,103,28,1104,2303,83,1068,176,1388,2146,177,1362,2491,226,2715,198,1374,2722,252,205
|
0.7625504930274744,2.208903801378106,3.418324905107978,0.0913519243495543,-0.5728876459442109,2.37360689336414,0.11977606936216245,1.748546271130567,-0.08224273671363029,-0.47760517435342253,1.748546271130567,-0.06757235345286404,-0.6861102721985591,1.4758017160295607,-0.8687252926726254,1.6192531761518294,-0.06757235345286404,-0.8687252926726254,1.4196539730392503,1.5754968368419882
| 3,069
|
SLC25 family of mitochondrial transporters
| 11
| 18
| 2.8995
| 0.003738
|
Q9Y619,Q9Y6C9,Q9HC21,O43808,Q9NZJ7,Q70HW3,Q9BQT8,P12235,Q6NUK1,Q9UBX3,P12236
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
130,259,425,521,205,54,95,344,220,30,439
|
594,521,815,816,344,439,1450,753,1134,220,54,95,425,205,30,1383,130,259
|
0.6344916702788778,0.7244341762651175,0.34219686706793473,0.34219686706793473,1.1184335679045274,0.8877944286969826,-0.11169757381838322,0.4234133694254319,0.07708640378612587,1.4981071031700752,2.8410618513115837,2.287002000595034,0.9248371557106364,1.5754968368419882,3.3943981532933445,-0.06757235345286404,1.9884673871689231,1.397039326426985
| 3,069
|
Mitochondrial carrier domain superfamily [IPR023395]
| 11
| 18
| 2.8995
| 0.003738
|
Q9Y619,Q9Y6C9,Q9HC21,O43808,Q9NZJ7,Q70HW3,Q9BQT8,P12235,Q6NUK1,Q9UBX3,P12236
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
130,259,425,521,205,54,95,344,220,30,439
|
594,521,815,816,344,439,1450,753,1134,220,54,95,425,205,30,1383,130,259
|
0.6344916702788778,0.7244341762651175,0.34219686706793473,0.34219686706793473,1.1184335679045274,0.8877944286969826,-0.11169757381838322,0.4234133694254319,0.07708640378612587,1.4981071031700752,2.8410618513115837,2.287002000595034,0.9248371557106364,1.5754968368419882,3.3943981532933445,-0.06757235345286404,1.9884673871689231,1.397039326426985
| 3,069
|
Mitochondrial substrate/solute carrier [IPR018108]
| 11
| 18
| 2.8995
| 0.003738
|
Q9Y619,Q9Y6C9,Q9HC21,O43808,Q9NZJ7,Q70HW3,Q9BQT8,P12235,Q6NUK1,Q9UBX3,P12236
|
Sequence
|
InterPro Repeat
|
interpro_repeat
|
130,259,425,521,205,54,95,344,220,30,439
|
594,521,815,816,344,439,1450,753,1134,220,54,95,425,205,30,1383,130,259
|
0.6344916702788778,0.7244341762651175,0.34219686706793473,0.34219686706793473,1.1184335679045274,0.8877944286969826,-0.11169757381838322,0.4234133694254319,0.07708640378612587,1.4981071031700752,2.8410618513115837,2.287002000595034,0.9248371557106364,1.5754968368419882,3.3943981532933445,-0.06757235345286404,1.9884673871689231,1.397039326426985
| 3,069
|
Organic acid transmembrane transporter activity
| 12
| 22
| 2.89644
| 0.003774
|
P08183,P53985,Q9Y619,O15439,O14975,Q96NB2,Q9H2J7,P30825,Q96QD8,P41440,Q9UBX3,Q9BQT8
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
157,225,130,413,573,459,402,305,503,379,30,95
|
573,413,815,828,157,759,305,379,1450,225,1134,599,2225,459,503,95,402,695,30,1383,1348,130
|
0.6603347615792099,0.9371314323192231,0.34219686706793473,0.3285473948164417,1.8226377360704582,0.4099575031857863,1.2128218563732212,1.0103454814086226,-0.11169757381838322,1.4758017160295607,0.07708640378612587,0.6215260224104379,-0.525046536969556,0.8629648599038147,0.7625504930274744,2.287002000595034,0.9738559787002006,0.5034874488366304,3.3943981532933445,-0.06757235345286404,-0.052939730621627525,1.9884673871689231
| 3,069
|
Protein maturation
| 21
| 65
| 2.892466
| 0.003822
|
P35670,Q92542,P62942,O75503,P49366,Q9UG56,Q5VZE5,Q9UMS0,O75844,Q8N4Q1,Q969M3,Q15392,Q86UY6,Q92896,P42892,Q8TCT9,P67812,Q5JRX3,Q10713,Q8TAD4,Q9BU89
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
257,392,17,146,274,145,407,299,48,313,451,194,195,329,78,80,211,214,226,116,122
|
702,2819,1472,1145,146,48,530,2898,1656,2766,2982,866,2706,2795,2486,2782,2513,2947,2709,2558,257,778,78,274,1993,1663,17,211,991,552,226,1421,1135,457,194,214,897,407,743,2391,195,313,116,80,392,329,451,1484,1916,2502,1561,825,1343,837,122,1618,1851,1346,2133,786,145,994,299,1319,1028
|
0.47692102554906757,-0.9880723020572022,-0.12648242619790095,0.06278501041697414,1.874978181937071,2.9457216164408178,0.7116718601694995,-1.127617485810929,-0.23106749871412027,-0.9195667969445095,-1.3619719918089834,0.30114984604267064,-0.8687252926726254,-0.9537161071859821,-0.6861102721985591,-0.9366157485523138,-0.702470899477358,-1.2526027748013133,-0.8687252926726254,-0.7353343403528879,1.397039326426985,0.3829499709628327,2.421160407074321,1.317174902542949,-0.39940650424205115,-0.23106749871412027,3.5598281788847492,1.5203256899968731,0.19022115610960058,0.686061138987713,1.4758017160295607,-0.09695107734044302,0.07708640378612587,0.8629648599038147,1.6410062740261269,1.509227204047994,0.2736197563045998,0.9616407296721227,0.43683750484696116,-0.6211353495660349,1.6410062740261269,1.2011083765302808,2.0796752385385897,2.3926757347254552,0.9860451122520546,1.1540124536294423,0.8753931646747174,-0.12648242619790095,-0.35299894149661604,-0.6861102721985591,-0.17106914307245863,0.34219686706793473,-0.052939730621627525,0.3285473948164417,2.0494339813351585,-0.2009891400311259,-0.3222698704241627,-0.052939730621627525,-0.4618790605702103,0.3829499709628327,1.8853889962920538,0.19022115610960058,1.236176913945832,-0.03834467281593642,0.16214771959355356
| 3,069
|
Endopeptidase activity
| 14
| 55
| 2.888272
| 0.003874
|
Q4J6C6,Q10713,P28072,Q16740,P28070,P42892,O75844,Q8TCT9,P67812,P49721,O14773,Q5JRX3,P49720,Q9NZ08
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
324,226,39,234,334,78,48,80,211,147,53,214,91,222
|
53,622,2510,1145,48,2900,1711,1712,2513,449,1089,2676,334,39,1774,2361,1738,1331,78,1685,2147,91,147,891,2309,2337,2177,1169,211,226,1748,2978,2443,234,324,214,897,688,1817,80,392,663,2946,1428,774,566,1561,725,825,1343,1825,222,1466,1275,1028
|
2.858638405195539,0.5824510420045746,-0.702470899477358,0.06278501041697414,2.9457216164408178,-1.127617485810929,-0.26130591781680096,-0.26130591781680096,-0.702470899477358,0.8753931646747174,0.10558175302512113,-0.8350823723193651,1.1421774665018345,3.207568222440519,-0.29170612358688064,-0.6050071745182394,-0.2764856883853633,-0.052939730621627525,2.421160407074321,-0.2461665934751816,-0.47760517435342253,2.316016170957344,1.874978181937071,0.2736197563045998,-0.5728876459442109,-0.5889246933797637,-0.4933749612214743,0.04844756194118684,1.5203256899968731,1.4758017160295607,-0.2764856883853633,-1.34359653403239,-0.6535298334803012,1.4534088423165563,1.1776090170448037,1.509227204047994,0.2736197563045998,0.5034874488366304,-0.3069674436057677,2.3926757347254552,0.9860451122520546,0.5299304956557244,-1.2345780792276917,-0.09695107734044302,0.39646975457854383,0.6732124730764801,-0.17106914307245863,0.46359118404072686,0.34219686706793473,-0.052939730621627525,-0.3069674436057677,1.4981071031700752,-0.11169757381838322,-0.009266478234315357,0.16214771959355356
| 3,069
|
Monooxygenase activity
| 6
| 9
| 2.886568
| 0.003895
|
Q15800,P09601,Q6UW02,P30519,Q16850,Q9BU89
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
66,26,37,10,84,122
|
26,10,1170,155,66,84,37,2547,122
|
3.450072877013566,3.750749419230711,0.04844756194118684,1.843631471229452,2.5522463606903325,2.37360689336414,3.224057986252734,-0.718878830028884,2.0494339813351585
| 3,069
|
Alcohol binding
| 9
| 16
| 2.886222
| 0.003899
|
O15118,O75477,P35610,P21796,O94905,O95772,P30536,Q14108,P45880
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,286,291,41,265,45,114,63,31
|
2578,192,1204,286,265,45,770,41,1601,2334,114,291,31,63,2914,325
|
-0.7518377093865654,1.6518518344930793,0.01966376346831093,1.282602169065299,1.3743347259546723,2.9887720797510466,0.39646975457854383,3.182744358294726,-0.2009891400311259,-0.5889246933797637,2.0796752385385897,1.2710312196614248,3.3623398601348073,2.5983448579795256,-1.145304659012404,1.1776090170448037
| 3,069
|
Pigmentary retinopathy
| 10
| 42
| 2.8795
| 0.003983
|
P53701,Q9P0J0,P00403,P21912,Q9UG56,P00846,Q7KZN9,P03915,Q96CU9,Q15067
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
65,74,141,176,145,18,245,273,160,323
|
1471,1351,1654,1568,1164,1521,1144,922,2299,1354,1802,141,18,273,1179,1415,1495,176,2768,2515,1388,1254,1045,956,2148,1992,65,2463,323,2840,2389,376,245,516,1459,160,982,2263,74,145,1516,2168
|
-0.12648242619790095,-0.06757235345286404,-0.23106749871412027,-0.18600945144458284,0.04844756194118684,-0.15616800678718376,0.06278501041697414,0.24595582673959437,-0.5728876459442109,-0.06757235345286404,-0.3069674436057677,1.90615390951366,3.536485172574649,1.317174902542949,0.03407387466120978,-0.09695107734044302,-0.14130583611076566,1.748546271130567,-0.9195667969445095,-0.702470899477358,-0.08224273671363029,-0.009266478234315357,0.13393505155524324,0.21815673924788037,-0.47760517435342253,-0.39940650424205115,2.570730314495249,-0.6697966741024561,1.1776090170448037,-1.0053287737997052,-0.6211353495660349,1.0224569394488752,1.430927787579856,0.7498733649115101,-0.11169757381838322,1.8226377360704582,0.2042060940190475,-0.5409488224408237,2.4870785513620435,1.8853889962920538,-0.14130583611076566,-0.47760517435342253
| 3,069
|
Ion homeostasis
| 37
| 108
| 2.873648
| 0.004058
|
P35670,P05023,Q15904,P50897,P30519,Q9H4I9,Q8NE01,Q9HD47,P62942,O75503,Q96A33,Q15043,P09601,Q8N511,Q8IYU8,Q93050,Q6P4Q7,Q8WWC4,O43819,P48507,P51790,P16615,Q16891,Q9BPX6,P78417,Q9Y6M7,P20020,Q96AQ8,P51572,Q13586,Q96PU5,P30536,Q8TAD4,Q14BN4,O75880,Q9HD20,Q8NEW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
257,509,514,2,10,11,524,15,17,146,149,533,26,27,546,161,307,184,581,584,585,333,467,468,598,342,597,349,351,364,366,114,116,375,246,125,126
|
2872,2885,2170,581,2703,1126,864,146,246,2898,953,717,1525,1656,604,2963,1088,509,1042,1493,1129,1104,1327,770,2057,26,2706,3043,2964,2512,2112,879,333,2486,2782,1446,597,2958,2306,2410,2709,888,2062,10,114,657,257,2537,2199,584,2,1417,351,585,1866,1781,1363,790,17,2836,598,991,2633,1579,364,2340,1869,375,533,1968,514,467,307,2696,546,2524,27,524,793,126,116,184,1316,161,149,349,1460,1916,366,873,468,1509,1346,1699,11,125,15,3023,2101,1409,994,904,1300,1028,670,2373,2761,342
|
-1.0748847085777697,-1.0924078528835213,-0.4933749612214743,0.6474278718372324,-0.8687252926726254,0.07708640378612587,0.30114984604267064,1.874978181937071,1.4196539730392503,-1.127617485810929,0.21815673924788037,0.46359118404072686,-0.15616800678718376,-0.23106749871412027,0.6085307928083136,-1.30702347104922,0.10558175302512113,0.7498733649115101,0.13393505155524324,-0.14130583611076566,0.07708640378612587,0.0913519243495543,-0.052939730621627525,0.39646975457854383,-0.4305568818174603,3.450072877013566,-0.8687252926726254,-2.004463803227854,-1.30702347104922,-0.702470899477358,-0.4618790605702103,0.28740144952661106,1.1421774665018345,-0.6861102721985591,-0.9366157485523138,-0.11169757381838322,0.6215260224104379,-1.2888250976967754,-0.5728876459442109,-0.637309480977452,-0.8687252926726254,0.2736197563045998,-0.4305568818174603,3.750749419230711,2.0796752385385897,0.5299304956557244,1.397039326426985,-0.718878830028884,-0.5091886663448594,0.6474278718372324,3.832785549048474,-0.09695107734044302,1.0945904112546285,0.6474278718372324,-0.33761362784204135,-0.29170612358688064,-0.06757235345286404,0.3693979985962563,3.5598281788847492,-1.0053287737997052,0.6215260224104379,0.19022115610960058,-0.7849891516950118,-0.18600945144458284,1.0466029531902257,-0.5889246933797637,-0.33761362784204135,1.0224569394488752,0.7116718601694995,-0.38389514937413705,0.7498733649115101,0.838026650861996,1.2128218563732212,-0.8518788914948365,0.6988808910665117,-0.702470899477358,3.442152330866641,0.7244341762651175,0.3693979985962563,2.0088619004284114,2.0796752385385897,1.716496296000973,-0.03834467281593642,1.8121118765241035,1.8645483697136485,1.1065244490846795,-0.11169757381838322,-0.35299894149661604,1.0466029531902257,0.30114984604267064,0.838026650861996,-0.14130583611076566,-0.052939730621627525,-0.2461665934751816,3.7357070891646837,2.0190319417003906,3.598523543210219,-1.6450079456876248,-0.446196376754283,-0.08224273671363029,0.19022115610960058,0.2736197563045998,-0.023786986148872924,0.16214771959355356,0.5299304956557244,-0.6050071745182394,-0.9025689417990336,1.1303178723762042
| 3,069
|
Blindness
| 24
| 79
| 2.86438
| 0.004178
|
Q9Y6M9,P50897,Q969G3,O43676,P00846,O43505,P07602,Q96CU9,Q86Y39,P21912,P06865,P49770,P53701,Q9H6K4,Q9NZJ7,O96000,P16278,Q99496,P31939,Q9NZ08,P46100,Q8N183,Q9NPL8,P17900
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
260,2,526,16,18,411,28,160,293,176,303,559,65,67,205,208,83,476,469,222,354,516,252,123
|
2215,702,1471,572,1385,2196,411,16,1164,1087,1521,1144,2084,922,2299,1354,2431,208,2766,18,954,1681,2886,303,28,1104,1179,83,123,1415,2357,176,2688,2768,1388,469,1776,1254,1331,778,354,1497,559,2148,1992,2,3024,1149,65,1393,1367,2255,2282,2840,2343,2184,293,2318,516,1850,1459,2698,526,160,1696,476,2189,2722,1296,67,252,1487,222,205,1565,2956,810,1516,260
|
-0.525046536969556,0.47692102554906757,-0.12648242619790095,0.6603347615792099,-0.08224273671363029,-0.5091886663448594,0.9493992521351239,3.590805302191555,0.04844756194118684,0.10558175302512113,-0.15616800678718376,0.06278501041697414,-0.446196376754283,0.24595582673959437,-0.5728876459442109,-0.06757235345286404,-0.6535298334803012,1.5314026455401484,-0.9195667969445095,3.536485172574649,0.21815673924788037,-0.2461665934751816,-1.0924078528835213,1.2128218563732212,3.418324905107978,0.0913519243495543,0.03407387466120978,2.37360689336414,2.039317917817865,-0.09695107734044302,-0.6050071745182394,1.748546271130567,-0.8518788914948365,-0.9195667969445095,-0.08224273671363029,0.8255165059800994,-0.29170612358688064,-0.009266478234315357,-0.052939730621627525,0.3829499709628327,1.0706471565843538,-0.14130583611076566,0.6732124730764801,-0.47760517435342253,-0.39940650424205115,3.832785549048474,-1.6838381886675047,0.06278501041697414,2.570730314495249,-0.08224273671363029,-0.06757235345286404,-0.5409488224408237,-0.5568957742270876,-1.0053287737997052,-0.5889246933797637,-0.4933749612214743,1.259436758440911,-0.5728876459442109,0.7498733649115101,-0.3222698704241627,-0.11169757381838322,-0.8518788914948365,0.7244341762651175,1.8226377360704582,-0.2461665934751816,0.8255165059800994,-0.4933749612214743,-0.8687252926726254,-0.023786986148872924,2.5522463606903325,1.4196539730392503,-0.12648242619790095,1.4981071031700752,1.5754968368419882,-0.17106914307245863,-1.2706849905550104,0.3558136826238937,-0.14130583611076566,1.397039326426985
| 3,069
|
Vascular skin abnormality
| 24
| 114
| 2.863095
| 0.004195
|
P35670,P00403,Q14739,P00846,P03915,Q06136,P10619,Q16625,P49257,O75844,P21912,Q9C0B1,Q14108,P53701,P51648,P22830,P21964,P16278,Q6NUK1,P06280,P04062,Q8IZA0,Q9NWM8,Q13126
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
257,141,272,18,273,279,25,165,167,48,176,181,63,65,71,202,204,83,220,230,103,106,108,109
|
702,3042,1654,2702,814,1204,2643,1248,1144,847,48,1441,2376,141,18,954,1356,273,103,1033,230,1657,2996,25,877,1894,2988,3020,83,2486,2782,1227,1495,2902,2357,176,204,202,2709,2893,2062,2434,1715,1776,2558,257,890,2115,420,2537,2064,354,707,167,1497,1308,71,3024,892,65,2517,1362,1901,2313,2838,1631,1393,1171,2544,279,2605,909,1037,1748,109,2827,364,63,1212,2635,272,2815,1750,1690,1969,165,2752,1724,220,2225,763,1190,106,1726,946,1874,2073,773,294,2446,1343,1080,181,2347,3001,108,1981,1143,2855,1925,1983,2053,1300,1984
|
0.47692102554906757,-2.004463803227854,-0.23106749871412027,-0.8687252926726254,0.34219686706793473,0.01966376346831093,-0.8016377952947211,-0.009266478234315357,0.06278501041697414,0.31486510761236025,2.9457216164408178,-0.11169757381838322,-0.6211353495660349,1.90615390951366,3.536485172574649,0.21815673924788037,-0.06757235345286404,1.317174902542949,2.208903801378106,0.1480588764572703,1.4534088423165563,-0.23106749871412027,-1.436075804697021,3.4579825093765058,0.28740144952661106,-0.35299894149661604,-1.398902708781335,-1.6256922666307558,2.37360689336414,-0.6861102721985591,-0.9366157485523138,0.005217041828054251,-0.14130583611076566,-1.127617485810929,-0.6050071745182394,1.748546271130567,1.5864673909793765,1.5974169115678218,-0.8687252926726254,-1.1099853317350328,-0.4305568818174603,-0.6535298334803012,-0.26130591781680096,-0.29170612358688064,-0.7353343403528879,1.397039326426985,0.2736197563045998,-0.4618790605702103,0.9248371557106364,-0.718878830028884,-0.4305568818174603,1.0706471565843538,0.47692102554906757,1.791001813576259,-0.14130583611076566,-0.03834467281593642,2.4964337739427047,-1.6838381886675047,0.2736197563045998,2.570730314495249,-0.702470899477358,-0.06757235345286404,-0.35299894149661604,-0.5728876459442109,-1.0053287737997052,-0.21600841862746054,-0.08224273671363029,0.04844756194118684,-0.718878830028884,1.305673915474619,-0.7683892185340218,0.25980460342637235,0.1480588764572703,-0.2764856883853633,2.1297246577528743,-0.9880723020572022,1.0466029531902257,2.5983448579795256,0.01966376346831093,-0.7849891516950118,1.3286527579296776,-0.970868186256457,-0.2764856883853633,-0.2461665934751816,-0.38389514937413705,1.8015665931551217,-0.9025689417990336,-0.26130591781680096,1.4981071031700752,-0.525046536969556,0.4099575031857863,0.03407387466120978,2.189211526994024,-0.26130591781680096,0.23207326087768618,-0.33761362784204135,-0.4305568818174603,0.39646975457854383,1.259436758440911,-0.6535298334803012,-0.052939730621627525,0.11977606936216245,1.7378829103625977,-0.5889246933797637,-1.4547542510082334,2.1694512293067545,-0.38389514937413705,0.07708640378612587,-1.0226379236492988,-0.35299894149661604,-0.38389514937413705,-0.4149603366787841,-0.023786986148872924,-0.38389514937413705
| 3,069
|
Vacuolar membrane
| 22
| 120
| 2.861643
| 0.004215
|
Q9NQX7,O75503,P10619,Q8N511,P07602,Q93050,Q16625,O95772,P42785,Q14108,O15118,P10253,P11117,O15260,Q9NZJ7,P42892,Q96GC9,Q9H2V7,Q8WTV0,Q8NF37,P04062,Q8IV08
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
135,146,25,27,28,161,165,45,59,63,192,193,197,201,205,78,93,221,98,228,103,127
|
2872,2885,192,201,703,2863,2171,727,1734,146,1598,2919,829,45,2849,103,907,866,28,1327,770,759,1043,1837,1526,193,25,197,2407,830,441,987,1713,2927,2835,1181,942,1071,1330,890,2537,1716,379,1531,59,78,1863,1532,1417,585,3024,970,851,1605,2944,483,990,614,1093,1363,2179,2467,2066,244,909,2606,1074,1424,63,533,165,1399,372,1190,127,1375,723,3005,27,228,98,3044,2320,392,161,1460,2500,3051,93,2262,621,1486,1343,1058,3054,1059,2291,857,1511,221,1827,631,874,556,135,714,1217,205,1159,571,1409,419,2951,2370,1060,1349,860,1300,862,520
|
-1.0748847085777697,-1.0924078528835213,1.6518518344930793,1.5974169115678218,0.47692102554906757,-1.057415561321741,-0.4933749612214743,0.4502300599193025,-0.2764856883853633,1.874978181937071,-0.2009891400311259,-1.1630471985041442,0.3285473948164417,2.9887720797510466,-1.0226379236492988,2.208903801378106,0.25980460342637235,0.30114984604267064,3.418324905107978,-0.052939730621627525,0.39646975457854383,0.4099575031857863,0.13393505155524324,-0.3222698704241627,-0.15616800678718376,1.6518518344930793,3.4579825093765058,1.6192531761518294,-0.637309480977452,0.3285473948164417,0.8877944286969826,0.19022115610960058,-0.26130591781680096,-1.1808454547556477,-1.0053287737997052,0.03407387466120978,0.23207326087768618,0.11977606936216245,-0.052939730621627525,0.2736197563045998,-0.718878830028884,-0.26130591781680096,1.0103454814086226,-0.15616800678718376,2.7074905411166843,2.421160407074321,-0.33761362784204135,-0.15616800678718376,-0.09695107734044302,0.6474278718372324,-1.6838381886675047,0.2042060940190475,0.31486510761236025,-0.2009891400311259,-1.2345780792276917,0.8004135279398286,0.19022115610960058,0.5955058451096693,0.10558175302512113,-0.06757235345286404,-0.4933749612214743,-0.6697966741024561,-0.4305568818174603,1.430927787579856,0.25980460342637235,-0.7683892185340218,0.11977606936216245,-0.09695107734044302,2.5983448579795256,0.7116718601694995,1.8015665931551217,-0.08224273671363029,1.0345427268960783,0.03407387466120978,1.9884673871689231,-0.06757235345286404,0.46359118404072686,-1.4922969882440174,3.442152330866641,1.4646162582043338,2.248086156847928,-2.0458508152965815,-0.5728876459442109,0.9860451122520546,1.8121118765241035,-0.11169757381838322,-0.6861102721985591,-2.5223104649289985,2.2966897459870523,-0.5409488224408237,0.5955058451096693,-0.12648242619790095,-0.052939730621627525,0.13393505155524324,-2.8959590136207396,0.13393505155524324,-0.5568957742270876,0.31486510761236025,-0.14130583611076566,1.4981071031700752,-0.3069674436057677,0.5824510420045746,0.30114984604267064,0.686061138987713,1.9474587995274868,0.47692102554906757,0.01966376346831093,1.5754968368419882,0.06278501041697414,0.6732124730764801,-0.08224273671363029,0.9371314323192231,-1.2526027748013133,-0.6050071745182394,0.13393505155524324,-0.052939730621627525,0.31486510761236025,-0.023786986148872924,0.31486510761236025,0.7371679684407813
| 3,069
|
Sensorimotor neuropathy
| 13
| 32
| 2.851026
| 0.004358
|
P05023,Q9Y2R0,O60313,P39210,Q8N2K0,P07196,P00403,Q9NZJ7,P00846,P03915,Q9NR77,P07602,P41440
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
509,9,414,453,423,261,141,205,18,273,185,28,379
|
1517,1123,414,1770,141,18,273,509,261,28,2459,2710,453,1045,379,1308,1230,2491,2463,1632,673,2416,1152,545,423,823,2367,185,2047,205,9,1028
|
-0.15616800678718376,0.07708640378612587,0.9371314323192231,-0.29170612358688064,1.90615390951366,3.536485172574649,1.317174902542949,0.7498733649115101,1.3856983154795637,3.418324905107978,-0.6697966741024561,-0.8687252926726254,0.8629648599038147,0.13393505155524324,1.0103454814086226,-0.03834467281593642,0.005217041828054251,-0.6861102721985591,-0.6697966741024561,-0.21600841862746054,0.5167243220793968,-0.637309480977452,0.06278501041697414,0.6988808910665117,0.9248371557106364,0.34219686706793473,-0.6050071745182394,1.7057728913838957,-0.4149603366787841,1.5754968368419882,3.832785549048474,0.16214771959355356
| 3,069
|
Abnormal mitochondria in muscle tissue
| 7
| 23
| 2.845057
| 0.00444
|
Q9Y6M9,P00403,O43676,O96000,P03915,Q9NPL8,Q96CU9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
260,141,16,208,273,252,160
|
1471,16,1521,1144,2084,922,208,141,273,1415,2768,1388,2148,293,516,1850,160,1296,252,1565,810,1028,260
|
-0.12648242619790095,3.590805302191555,-0.15616800678718376,0.06278501041697414,-0.446196376754283,0.24595582673959437,1.5314026455401484,1.90615390951366,1.317174902542949,-0.09695107734044302,-0.9195667969445095,-0.08224273671363029,-0.47760517435342253,1.259436758440911,0.7498733649115101,-0.3222698704241627,1.8226377360704582,-0.023786986148872924,1.4196539730392503,-0.17106914307245863,0.3558136826238937,0.16214771959355356,1.397039326426985
| 3,069
|
Lower limb spasticity
| 25
| 78
| 2.837919
| 0.004541
|
Q9Y619,O94905,Q9Y5Y5,O75298,P00846,P07602,Q96CU9,O75477,O60313,Q9UBB4,P21912,P56589,Q99720,Q9H6K4,Q5XKP0,Q9P0J0,O00400,Q9NZJ7,Q15041,Q6DKK2,P04062,P35637,P46100,P07942,Q7KZN9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
130,265,404,394,18,28,160,286,414,302,176,435,314,67,198,74,328,205,339,100,103,232,354,491,245
|
1471,2596,328,1517,1351,2847,1568,414,1521,394,1144,286,922,847,265,1802,1770,2899,2353,18,103,2900,28,491,1179,2795,3052,2457,1415,176,2768,2515,1388,232,354,1574,2148,1548,1308,2176,2223,1362,2491,1901,2661,435,1632,3033,1937,339,1786,2389,1112,1292,1054,198,100,245,516,1458,2159,823,160,1644,1429,314,1727,1619,67,2324,205,74,302,1319,2053,1028,404,130
|
-0.12648242619790095,-0.7683892185340218,1.1540124536294423,-0.15616800678718376,-0.06757235345286404,-1.0226379236492988,-0.18600945144458284,0.9371314323192231,-0.15616800678718376,0.9738559787002006,0.06278501041697414,1.282602169065299,0.24595582673959437,0.31486510761236025,1.3743347259546723,-0.3069674436057677,-0.29170612358688064,-1.127617485810929,-0.6050071745182394,3.536485172574649,2.208903801378106,-1.127617485810929,3.418324905107978,0.7878204493186719,0.03407387466120978,-0.9537161071859821,-2.7294357611225606,-0.6697966741024561,-0.09695107734044302,1.748546271130567,-0.9195667969445095,-0.702470899477358,-0.08224273671363029,1.4534088423165563,1.0706471565843538,-0.18600945144458284,-0.47760517435342253,-0.17106914307245863,-0.03834467281593642,-0.4933749612214743,-0.525046536969556,-0.06757235345286404,-0.6861102721985591,-0.35299894149661604,-0.8183354383139178,0.9001687703022228,-0.21600841862746054,-1.841879764249894,-0.3684260388829964,1.1303178723762042,-0.29170612358688064,-0.6211353495660349,0.0913519243495543,-0.023786986148872924,0.13393505155524324,1.6192531761518294,2.2383156968635576,1.430927787579856,0.7498733649115101,-0.11169757381838322,-0.47760517435342253,0.34219686706793473,1.8226377360704582,-0.21600841862746054,-0.09695107734044302,1.2011083765302808,-0.26130591781680096,-0.2009891400311259,2.5522463606903325,-0.5728876459442109,1.5754968368419882,2.4870785513620435,1.2245113358720499,-0.03834467281593642,-0.4149603366787841,0.16214771959355356,0.9738559787002006,1.9884673871689231
| 3,069
|
Organic anion transmembrane transporter activity
| 16
| 32
| 2.832735
| 0.004615
|
P53985,Q9Y619,O15439,Q9HC21,Q96NB2,O00400,Q8TB61,P30825,Q9Y6M7,Q9BQT8,P12235,Q96QD8,Q6NUK1,P41440,Q9UBX3,P12236
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
225,130,413,425,459,328,120,305,342,95,344,503,220,379,30,439
|
328,413,521,815,828,816,759,3052,344,439,305,379,1450,225,1134,754,599,220,2225,1375,120,459,503,934,95,695,425,30,1383,1348,130,342
|
1.1540124536294423,0.9371314323192231,0.7244341762651175,0.34219686706793473,0.3285473948164417,0.34219686706793473,0.4099575031857863,-2.7294357611225606,1.1184335679045274,0.8877944286969826,1.2128218563732212,1.0103454814086226,-0.11169757381838322,1.4758017160295607,0.07708640378612587,0.4234133694254319,0.6215260224104379,1.4981071031700752,-0.525046536969556,-0.06757235345286404,2.05953218036522,0.8629648599038147,0.7625504930274744,0.24595582673959437,2.287002000595034,0.5034874488366304,0.9248371557106364,3.3943981532933445,-0.06757235345286404,-0.052939730621627525,1.9884673871689231,1.1303178723762042
| 3,069
|
Alpha/Beta hydrolase fold [IPR029058]
| 11
| 26
| 2.832357
| 0.004621
|
Q9HB40,Q4J6C6,P50897,Q9UMR5,Q8NCC3,Q9H3G5,P07099,Q9NUJ1,P10619,P42785,P38571
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
6,324,2,42,239,212,374,86,25,59,416
|
1032,374,25,2901,1711,943,416,59,2147,1497,2,324,2156,1056,1872,423,239,2042,900,3054,212,6,86,2050,42,2297
|
0.1480588764572703,1.0224569394488752,3.4579825093765058,-1.127617485810929,-0.26130591781680096,0.23207326087768618,0.9371314323192231,2.7074905411166843,-0.47760517435342253,-0.14130583611076566,3.832785549048474,1.1776090170448037,-0.47760517435342253,0.13393505155524324,-0.33761362784204135,0.9248371557106364,1.4421793813029162,-0.4149603366787841,0.2736197563045998,-2.8959590136207396,1.5203256899968731,3.832785549048474,2.3352775446813796,-0.4149603366787841,3.132771992491563,-0.5568957742270876
| 3,069
|
Receptor
| 19
| 39
| 2.816816
| 0.00485
|
Q9NS69,O00264,P55899,Q14739,O15031,Q99623,P10586,P30825,O15173,Q99720,Q14108,O15118,Q9UNN8,Q15758,Q15375,Q9Y5M8,Q8WTV0,P02786,P35613
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
7,138,270,272,405,547,540,305,56,314,63,192,216,599,345,99,98,604,249
|
138,405,192,56,604,1034,848,865,2302,1771,2058,540,830,777,1712,987,305,249,270,909,1233,63,974,272,345,599,1152,98,3059,2896,621,547,314,7,216,2371,1545,99,2194
|
1.9165081464838196,0.9616407296721227,1.6518518344930793,2.7523611907771843,0.6085307928083136,0.1480588764572703,0.31486510761236025,0.30114984604267064,-0.5728876459442109,-0.29170612358688064,-0.4305568818174603,0.6988808910665117,0.3285473948164417,0.3829499709628327,-0.26130591781680096,0.19022115610960058,1.2128218563732212,1.4196539730392503,1.3401075752242395,0.25980460342637235,0.005217041828054251,2.5983448579795256,0.2042060940190475,1.3286527579296776,1.1184335679045274,0.6215260224104379,0.06278501041697414,2.248086156847928,-3.2702671049494385,-1.1099853317350328,0.5955058451096693,0.6988808910665117,1.2011083765302808,3.832785549048474,1.509227204047994,-0.6050071745182394,-0.15616800678718376,2.248086156847928,-0.4933749612214743
| 3,069
|
Increased csf lactate
| 14
| 53
| 2.816422
| 0.004856
|
Q9Y6M9,Q86Y39,P39210,Q9HC21,Q9P0J0,P00403,O43676,O96000,P00846,Q7KZN9,P03915,Q9NPL8,P13073,Q96CU9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
260,293,453,425,74,141,16,208,18,245,273,252,440,160
|
1471,2596,1351,16,1568,581,1521,1144,2084,922,1802,1770,208,141,18,273,1179,440,1415,2768,2515,1388,1331,453,2117,2146,2148,2176,1310,1499,2383,2389,1292,1314,245,1849,293,516,2895,898,1850,2569,160,1057,1793,2722,1296,425,252,1565,74,810,260
|
-0.12648242619790095,-0.7683892185340218,-0.06757235345286404,3.590805302191555,-0.18600945144458284,0.6474278718372324,-0.15616800678718376,0.06278501041697414,-0.446196376754283,0.24595582673959437,-0.3069674436057677,-0.29170612358688064,1.5314026455401484,1.90615390951366,3.536485172574649,1.317174902542949,0.03407387466120978,0.8877944286969826,-0.09695107734044302,-0.9195667969445095,-0.702470899477358,-0.08224273671363029,-0.052939730621627525,0.8629648599038147,-0.4618790605702103,-0.47760517435342253,-0.47760517435342253,-0.4933749612214743,-0.03834467281593642,-0.14130583611076566,-0.6211353495660349,-0.6211353495660349,-0.023786986148872924,-0.03834467281593642,1.430927787579856,-0.3222698704241627,1.259436758440911,0.7498733649115101,-1.1099853317350328,0.2736197563045998,-0.3222698704241627,-0.7353343403528879,1.8226377360704582,0.13393505155524324,-0.29170612358688064,-0.8687252926726254,-0.023786986148872924,0.9248371557106364,1.4196539730392503,-0.17106914307245863,2.4870785513620435,0.3558136826238937,1.397039326426985
| 3,069
|
Sphingolipid metabolism
| 8
| 10
| 2.81638
| 0.004857
|
O95470,P04062,Q13510,Q06136,Q16880,O15269,P17900,P07602
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
162,103,46,279,306,213,123,28
|
213,1123,162,103,28,123,279,46,306,403
|
1.509227204047994,0.07708640378612587,1.8015665931551217,2.208903801378106,3.418324905107978,2.039317917817865,1.305673915474619,2.9715906698002557,1.2128218563732212,0.9738559787002006
| 3,069
|
Aerobic respiration
| 15
| 83
| 2.816248
| 0.004859
|
O14949,O75964,Q9Y6M9,P20674,P00403,O43676,P14406,P00846,Q9UDW1,P21912,O96000,Q7KZN9,P03915,Q15070,P24539
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
32,64,260,200,141,16,111,18,19,176,208,245,273,190,158
|
1471,1351,32,1064,16,1568,1164,1521,1144,2084,2375,922,1015,1177,64,478,1802,208,141,18,273,865,1129,1473,1179,887,1225,1737,1226,1282,440,111,2019,1712,1494,1772,1415,200,2958,176,1089,158,2359,2768,1958,1839,1388,732,1840,1449,1044,2114,2116,2117,1717,1046,2824,2460,2148,1992,1310,1499,2491,1258,434,2181,625,190,1111,2389,1691,245,2475,2870,2504,2757,638,332,2479,19,994,810,260
|
-0.12648242619790095,-0.06757235345286404,3.3301014796516952,0.11977606936216245,3.590805302191555,-0.18600945144458284,0.04844756194118684,-0.15616800678718376,0.06278501041697414,-0.446196376754283,-0.6211353495660349,0.24595582673959437,0.16214771959355356,0.03407387466120978,2.589154797629924,0.8129788391133055,-0.3069674436057677,1.5314026455401484,1.90615390951366,3.536485172574649,1.317174902542949,0.30114984604267064,0.07708640378612587,-0.12648242619790095,0.03407387466120978,0.2736197563045998,0.005217041828054251,-0.2764856883853633,0.005217041828054251,-0.023786986148872924,0.8877944286969826,2.1097574181491536,-0.4149603366787841,-0.26130591781680096,-0.14130583611076566,-0.29170612358688064,-0.09695107734044302,1.608345479738206,-1.2888250976967754,1.748546271130567,0.10558175302512113,1.8226377360704582,-0.6050071745182394,-0.9195667969445095,-0.38389514937413705,-0.3222698704241627,-0.08224273671363029,0.4502300599193025,-0.3222698704241627,-0.11169757381838322,0.13393505155524324,-0.4618790605702103,-0.4618790605702103,-0.4618790605702103,-0.26130591781680096,0.13393505155524324,-0.9880723020572022,-0.6697966741024561,-0.47760517435342253,-0.39940650424205115,-0.03834467281593642,-0.14130583611076566,-0.6861102721985591,-0.009266478234315357,0.9001687703022228,-0.4933749612214743,0.5824510420045746,1.6626768412225865,0.0913519243495543,-0.6211353495660349,-0.2461665934751816,1.430927787579856,-0.6697966741024561,-1.057415561321741,-0.6861102721985591,-0.9025689417990336,0.5693662452264238,1.1540124536294423,-0.6697966741024561,3.505212800461361,0.19022115610960058,0.3558136826238937,1.397039326426985
| 3,069
|
Poor head control
| 15
| 73
| 2.812083
| 0.004922
|
Q10713,Q9Y6M9,Q86Y39,Q5XKP0,Q9P0J0,P00374,Q9NWM8,Q9NZJ7,O43676,P21912,O96000,Q9NPL8,P17900,P07602,Q96CU9
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
226,260,293,198,74,43,108,205,16,176,208,252,123,28,160
|
1471,2885,548,16,2744,1521,1144,2454,2084,1145,922,1802,1165,829,208,43,1356,1357,303,28,395,440,123,1415,176,2459,2768,1388,2537,2117,2660,2380,2148,1310,1450,1499,2223,1168,1000,2467,1998,2066,2784,2631,720,226,974,780,1152,1292,198,978,293,516,1850,2569,160,1484,2367,2722,1296,1920,252,1622,108,205,1565,74,2010,1348,810,1516,260
|
-0.12648242619790095,-1.0924078528835213,0.686061138987713,3.590805302191555,-0.9025689417990336,-0.15616800678718376,0.06278501041697414,-0.6697966741024561,-0.446196376754283,0.06278501041697414,0.24595582673959437,-0.3069674436057677,0.04844756194118684,0.3285473948164417,1.5314026455401484,3.1076215791981863,-0.06757235345286404,-0.06757235345286404,1.2128218563732212,3.418324905107978,0.9738559787002006,0.8877944286969826,2.039317917817865,-0.09695107734044302,1.748546271130567,-0.6697966741024561,-0.9195667969445095,-0.08224273671363029,-0.718878830028884,-0.4618790605702103,-0.8183354383139178,-0.6211353495660349,-0.47760517435342253,-0.03834467281593642,-0.11169757381838322,-0.14130583611076566,-0.525046536969556,0.04844756194118684,0.17620175517461098,-0.6697966741024561,-0.39940650424205115,-0.4305568818174603,-0.9366157485523138,-0.7849891516950118,0.46359118404072686,1.4758017160295607,0.2042060940190475,0.3829499709628327,0.06278501041697414,-0.023786986148872924,1.6192531761518294,0.2042060940190475,1.259436758440911,0.7498733649115101,-0.3222698704241627,-0.7353343403528879,1.8226377360704582,-0.12648242619790095,-0.6050071745182394,-0.8687252926726254,-0.023786986148872924,-0.35299894149661604,1.4196539730392503,-0.2009891400311259,2.1694512293067545,1.5754968368419882,-0.17106914307245863,2.4870785513620435,-0.39940650424205115,-0.052939730621627525,0.3558136826238937,-0.14130583611076566,1.397039326426985
| 3,069
|
Nucleotide transport
| 10
| 14
| 2.810431
| 0.004948
|
O15439,Q9HC21,O00400,Q6NUK1,Q8TDW0,P12235,Q08722,Q8TB61,P41440,P12236
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
413,425,328,220,408,344,317,120,379,439
|
328,413,521,816,344,439,379,317,220,1375,120,408,934,425
|
1.1540124536294423,0.9371314323192231,0.7244341762651175,0.34219686706793473,1.1184335679045274,0.8877944286969826,1.0103454814086226,1.1893707968069043,1.4981071031700752,-0.06757235345286404,2.05953218036522,0.9616407296721227,0.24595582673959437,0.9248371557106364
| 3,069
|
Sphingolipid metabolism integrated pathway
| 7
| 9
| 2.807248
| 0.004997
|
P27544,O95470,O15121,Q13510,Q96G23,Q06136,O15269
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
96,162,267,46,79,279,213
|
267,213,1123,162,96,279,46,306,79
|
1.3629484670588288,1.509227204047994,0.07708640378612587,1.8015665931551217,2.2772978253938296,1.305673915474619,2.9715906698002557,1.2128218563732212,2.40218638453676
| 3,069
|
Sphingolipid metabolism overview
| 7
| 9
| 2.807248
| 0.004997
|
P27544,O95470,O15121,Q13510,Q96G23,Q06136,O15269
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
96,162,267,46,79,279,213
|
267,213,1123,162,96,279,46,306,79
|
1.3629484670588288,1.509227204047994,0.07708640378612587,1.8015665931551217,2.2772978253938296,1.305673915474619,2.9715906698002557,1.2128218563732212,2.40218638453676
| 3,069
|
Iron ion binding
| 10
| 20
| 2.799746
| 0.005114
|
Q15800,Q6UW02,P22830,Q9UMS0,O15460,P13674,Q9C0B1,Q16850,Q9BU89,P31350
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
66,37,202,299,426,396,181,84,122,315
|
1733,426,814,1860,396,202,2709,315,1721,1393,66,84,442,37,2757,122,1297,181,2265,299
|
-0.2764856883853633,0.912516307045338,0.34219686706793473,-0.33761362784204135,0.9738559787002006,1.5974169115678218,-0.8687252926726254,1.1893707968069043,-0.26130591781680096,-0.08224273671363029,2.5522463606903325,2.37360689336414,0.8877944286969826,3.224057986252734,-0.9025689417990336,2.0494339813351585,-0.023786986148872924,1.7378829103625977,-0.5409488224408237,1.236176913945832
| 3,069
|
oxidoreductase
| 14
| 44
| 2.795067
| 0.005189
|
O43169,O14949,Q9Y6M9,Q86Y39,Q16134,Q8N0U8,P00403,O43676,O96000,P03915,Q8N4Q0,Q9Y320,P16435,Q15067
|
Functions
|
Panther Protein class
|
panther_protein_class
|
0,32,260,293,458,76,141,16,208,273,183,446,154,323
|
1471,1351,32,1012,0,1124,1064,16,1568,1144,2084,478,1770,208,141,273,2963,1225,1528,154,2688,2022,2769,2246,2028,2148,1310,1665,1813,323,458,1111,2389,2650,1505,293,76,183,3048,1916,2722,1378,446,260
|
-0.12648242619790095,-0.06757235345286404,3.3301014796516952,0.16214771959355356,3.832785549048474,0.07708640378612587,0.11977606936216245,3.590805302191555,-0.18600945144458284,0.06278501041697414,-0.446196376754283,0.8129788391133055,-0.29170612358688064,1.5314026455401484,1.90615390951366,1.317174902542949,-1.30702347104922,0.005217041828054251,-0.15616800678718376,1.843631471229452,-0.8518788914948365,-0.4149603366787841,-0.9195667969445095,-0.5409488224408237,-0.4149603366787841,-0.47760517435342253,-0.03834467281593642,-0.23106749871412027,-0.3069674436057677,1.1776090170448037,0.8629648599038147,0.0913519243495543,-0.6211353495660349,-0.8016377952947211,-0.14130583611076566,1.259436758440911,2.458920809217835,1.716496296000973,-2.2359361102244577,-0.35299894149661604,-0.8687252926726254,-0.06757235345286404,0.8877944286969826,1.397039326426985
| 3,069
|
Abnormal biliary tract morphology
| 7
| 21
| 2.79214
| 0.005236
|
Q10713,Q5XKP0,P04062,Q9NZJ7,P09601,P07602,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
226,198,103,205,26,28,63
|
497,1356,103,28,26,2686,1570,1331,1230,226,1748,63,272,198,2946,1560,2574,205,1008,799,1984
|
0.7625504930274744,-0.06757235345286404,2.208903801378106,3.418324905107978,3.450072877013566,-0.8518788914948365,-0.18600945144458284,-0.052939730621627525,0.005217041828054251,1.4758017160295607,-0.2764856883853633,2.5983448579795256,1.3286527579296776,1.6192531761518294,-1.2345780792276917,-0.17106914307245863,-0.7353343403528879,1.5754968368419882,0.17620175517461098,0.3693979985962563,-0.38389514937413705
| 3,069
|
Glycosphingolipid metabolic process
| 6
| 9
| 2.776152
| 0.005501
|
P06280,P04062,Q99805,P16278,P06865,P17900
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
230,103,298,83,303,123
|
103,230,303,1104,83,123,1171,306,298
|
2.208903801378106,1.4534088423165563,1.2128218563732212,0.0913519243495543,2.37360689336414,2.039317917817865,0.04844756194118684,1.2128218563732212,1.236176913945832
| 3,069
|
Protein transporter activity
| 6
| 14
| 2.773036
| 0.005554
|
Q9NS69,O60830,O14925,Q99595,Q9Y584,Q9HD20
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
7,1,38,5,44,125
|
38,1,952,648,454,2122,2585,913,5,125,7,681,44,254
|
3.207568222440519,3.832785549048474,0.21815673924788037,0.5431061127497685,0.8629648599038147,-0.4618790605702103,-0.7518377093865654,0.25980460342637235,3.832785549048474,2.0190319417003906,3.832785549048474,0.5167243220793968,3.090793151825162,1.4196539730392503
| 3,069
|
Abnormality of the tongue
| 24
| 86
| 2.756851
| 0.005836
|
P07196,P51114,O94905,Q9Y5Y5,Q96A33,Q7LGA3,P40855,Q13510,O15460,O75844,P21912,P56589,Q9C0B1,Q9Y4P3,P98175,O75381,P10253,P61978,P16278,Q6NUK1,Q9BQT8,Q10713,P46100,O43924
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
261,137,265,404,149,169,300,46,426,48,176,435,181,447,189,319,193,455,83,220,95,226,354,369
|
702,2639,2846,2847,1440,2106,426,369,1126,1087,319,1065,48,265,2658,1770,954,1356,1033,261,1104,1837,193,2272,83,1068,1713,2902,176,2835,2062,889,300,354,1743,707,1497,137,2030,2491,435,455,1364,2202,2466,189,1261,895,1171,226,1632,1367,1395,46,2469,1212,2859,1479,553,1505,220,169,526,149,1460,745,1266,476,2505,95,1727,181,1619,1699,2654,2447,1622,1795,2324,1143,2791,447,2240,1516,404,2168
|
0.47692102554906757,-0.8016377952947211,-1.0226379236492988,-1.0226379236492988,-0.11169757381838322,-0.4618790605702103,0.912516307045338,1.0345427268960783,0.07708640378612587,0.10558175302512113,1.1776090170448037,0.11977606936216245,2.9457216164408178,1.3743347259546723,-0.8183354383139178,-0.29170612358688064,0.21815673924788037,-0.06757235345286404,0.1480588764572703,1.3856983154795637,0.0913519243495543,-0.3222698704241627,1.6518518344930793,-0.5568957742270876,2.37360689336414,0.11977606936216245,-0.26130591781680096,-1.127617485810929,1.748546271130567,-1.0053287737997052,-0.4305568818174603,0.2736197563045998,1.2245113358720499,1.0706471565843538,-0.2764856883853633,0.47692102554906757,-0.14130583611076566,1.9371605235671987,-0.4149603366787841,-0.6861102721985591,0.9001687703022228,0.8629648599038147,-0.06757235345286404,-0.5091886663448594,-0.6697966741024561,1.6734813725808344,-0.009266478234315357,0.2736197563045998,0.04844756194118684,1.4758017160295607,-0.21600841862746054,-0.06757235345286404,-0.08224273671363029,2.9715906698002557,-0.6697966741024561,0.01966376346831093,-1.0400000767620767,-0.12648242619790095,0.686061138987713,-0.14130583611076566,1.4981071031700752,1.791001813576259,0.7244341762651175,1.8645483697136485,-0.11169757381838322,0.43683750484696116,-0.009266478234315357,0.8255165059800994,-0.6861102721985591,2.287002000595034,-0.26130591781680096,1.7378829103625977,-0.2009891400311259,-0.2461665934751816,-0.8016377952947211,-0.6535298334803012,-0.2009891400311259,-0.29170612358688064,-0.5728876459442109,0.07708640378612587,-0.9366157485523138,0.8877944286969826,-0.525046536969556,-0.14130583611076566,0.9738559787002006,-0.47760517435342253
| 3,069
|
Endoplasmic reticulum lumen
| 27
| 58
| 2.755146
| 0.005867
|
O75718,Q9H173,O95881,P13674,Q96AY3,Q02818,Q9BTV4,Q13217,Q15293,O43852,P07237,Q9BS26,O15460,Q14257,Q32P28,O00584,O14975,Q9Y680,Q8IXB1,Q8TED1,Q9NZ08,Q5JRA6,P07942,Q9NWM8,O43681,Q07065,Q9BTY2
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
508,644,269,396,150,24,284,673,429,166,172,568,426,57,442,191,573,77,462,463,222,617,491,108,497,244,124
|
191,1162,573,426,497,166,814,508,269,172,491,2901,1527,396,1305,879,2823,2535,2306,2709,741,2062,817,1738,1739,1993,2337,3055,24,244,673,974,57,1637,1668,429,442,617,688,822,1426,462,1673,2736,930,463,2232,150,1916,568,284,124,644,108,2048,222,2267,77
|
1.6518518344930793,0.04844756194118684,0.6603347615792099,0.912516307045338,0.7625504930274744,1.791001813576259,0.34219686706793473,0.7498733649115101,1.3401075752242395,1.7804174649941509,0.7878204493186719,-1.127617485810929,-0.15616800678718376,0.9738559787002006,-0.03834467281593642,0.28740144952661106,-0.9880723020572022,-0.718878830028884,-0.5728876459442109,-0.8687252926726254,0.43683750484696116,-0.4305568818174603,0.34219686706793473,-0.2764856883853633,-0.2764856883853633,-0.39940650424205115,-0.5889246933797637,-3.0675485201008637,3.4658812582260823,1.430927787579856,0.5167243220793968,0.2042060940190475,2.743415131391064,-0.21600841862746054,-0.23106749871412027,0.912516307045338,0.8877944286969826,0.5955058451096693,0.5034874488366304,0.34219686706793473,-0.09695107734044302,0.8505093952684031,-0.23106749871412027,-0.885621875365509,0.24595582673959437,0.8505093952684031,-0.525046536969556,1.8645483697136485,-0.35299894149661604,0.6732124730764801,1.2941497025621402,2.039317917817865,0.5562513155435278,2.1694512293067545,-0.4149603366787841,1.4981071031700752,-0.5409488224408237,2.4306238848658914
| 3,069
|
Oxidoreductase activity
| 56
| 231
| 2.754742
| 0.005874
|
O43169,Q9Y6M9,P30519,O15121,Q9NZ01,P00403,Q8NB78,O95881,O43676,Q14739,Q9UDW1,P13674,P03915,Q06136,P16435,P09601,Q14534,Q9UHG3,Q96CU9,Q96JJ7,O15439,Q6UW02,P00374,P07237,Q9BY49,O15460,P21912,Q9C0B1,Q8N4Q0,Q8N4Q1,Q3SXM5,P31350,Q9Y320,P13073,Q32P28,Q15067,Q15800,Q15392,P51648,P20674,Q9P0J0,Q16134,Q8N0U8,Q9H9P8,Q8IXB1,O96000,Q16850,Q9H3N1,Q6NUM9,Q8NBX0,Q9H7Z7,P14406,Q7KZN9,Q16836,Q9BU89,Q8NBN7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
0,260,10,267,403,141,142,269,16,272,19,396,273,279,154,26,155,29,160,417,413,37,43,172,431,426,176,181,183,313,58,315,446,440,442,323,66,194,71,200,74,458,76,465,462,208,84,341,346,224,243,111,245,376,122,383
|
964,1471,2596,1733,1351,3061,768,267,1012,413,426,0,749,1124,2873,1064,16,1568,2640,581,1164,1890,814,2620,1860,1521,1144,2084,922,1015,2898,3047,478,1802,1770,739,269,208,2141,1146,43,967,2644,141,2766,273,2963,2645,2109,2483,172,1179,887,2921,2303,26,1225,1737,1226,1282,2111,2059,2599,1988,1955,1283,440,1527,396,1528,671,111,2484,2485,2965,771,154,1415,200,176,2688,2022,1895,2536,1206,2410,888,2768,2334,2877,880,2769,881,1738,10,3017,1388,315,732,2145,1775,1715,2435,684,2246,2116,2117,1045,988,2601,1046,2028,584,2460,2647,1497,3029,1416,2148,1992,1228,71,1229,1230,1310,2602,2249,1362,2463,2150,3019,1170,598,3040,2181,1551,1393,279,1665,1421,1135,625,1813,155,272,3035,323,1668,194,1969,66,458,1111,2389,376,84,2567,442,58,2650,1018,1425,1505,977,1909,346,2125,37,872,627,2226,245,2157,2547,2498,2391,2472,462,76,2524,183,313,3048,2803,142,383,690,224,2668,1482,463,1458,1155,2039,2161,1975,160,1916,417,2504,630,2722,738,1317,836,122,1509,1297,431,181,341,2265,243,2321,465,631,2681,2759,403,74,1143,1796,2009,19,29,2808,2617,1276,446,844,260
|
0.2042060940190475,-0.12648242619790095,-0.7683892185340218,-0.2764856883853633,-0.06757235345286404,-3.400772477141138,0.39646975457854383,1.3629484670588288,0.16214771959355356,0.9371314323192231,0.912516307045338,3.832785549048474,0.4234133694254319,0.07708640378612587,-1.0748847085777697,0.11977606936216245,3.590805302191555,-0.18600945144458284,-0.8016377952947211,0.6474278718372324,0.04844756194118684,-0.35299894149661604,0.34219686706793473,-0.7849891516950118,-0.33761362784204135,-0.15616800678718376,0.06278501041697414,-0.446196376754283,0.24595582673959437,0.16214771959355356,-1.127617485810929,-2.1718614165143197,0.8129788391133055,-0.3069674436057677,-0.29170612358688064,0.43683750484696116,1.3401075752242395,1.5314026455401484,-0.47760517435342253,0.06278501041697414,3.1076215791981863,0.2042060940190475,-0.8016377952947211,1.90615390951366,-0.9195667969445095,1.317174902542949,-1.30702347104922,-0.8016377952947211,-0.4618790605702103,-0.6861102721985591,1.7804174649941509,0.03407387466120978,0.2736197563045998,-1.1630471985041442,-0.5728876459442109,3.450072877013566,0.005217041828054251,-0.2764856883853633,0.005217041828054251,-0.023786986148872924,-0.4618790605702103,-0.4305568818174603,-0.7683892185340218,-0.39940650424205115,-0.38389514937413705,-0.023786986148872924,0.8877944286969826,-0.15616800678718376,0.9738559787002006,-0.15616800678718376,0.5167243220793968,2.1097574181491536,-0.6861102721985591,-0.6861102721985591,-1.30702347104922,0.39646975457854383,1.843631471229452,-0.09695107734044302,1.608345479738206,1.748546271130567,-0.8518788914948365,-0.4149603366787841,-0.35299894149661604,-0.718878830028884,0.01966376346831093,-0.637309480977452,0.2736197563045998,-0.9195667969445095,-0.5889246933797637,-1.0748847085777697,0.28740144952661106,-0.9195667969445095,0.28740144952661106,-0.2764856883853633,3.750749419230711,-1.5872575262462856,-0.08224273671363029,1.1893707968069043,0.4502300599193025,-0.47760517435342253,-0.29170612358688064,-0.26130591781680096,-0.6535298334803012,0.5034874488366304,-0.5409488224408237,-0.4618790605702103,-0.4618790605702103,0.13393505155524324,0.19022115610960058,-0.7683892185340218,0.13393505155524324,-0.4149603366787841,0.6474278718372324,-0.6697966741024561,-0.8016377952947211,-0.14130583611076566,-1.742587709606113,-0.09695107734044302,-0.47760517435342253,-0.39940650424205115,0.005217041828054251,2.4964337739427047,0.005217041828054251,0.005217041828054251,-0.03834467281593642,-0.7683892185340218,-0.5409488224408237,-0.06757235345286404,-0.6697966741024561,-0.47760517435342253,-1.6064422764023063,0.04844756194118684,0.6215260224104379,-1.9838833450363904,-0.4933749612214743,-0.17106914307245863,-0.08224273671363029,1.305673915474619,-0.23106749871412027,-0.09695107734044302,0.07708640378612587,0.5824510420045746,-0.3069674436057677,1.843631471229452,1.3286527579296776,-1.8619490184330467,1.1776090170448037,-0.23106749871412027,1.6410062740261269,-0.38389514937413705,2.5522463606903325,0.8629648599038147,0.0913519243495543,-0.6211353495660349,1.0224569394488752,2.37360689336414,-0.7353343403528879,0.8877944286969826,2.716492830368516,-0.8016377952947211,0.16214771959355356,-0.09695107734044302,-0.14130583611076566,0.2042060940190475,-0.35299894149661604,1.1065244490846795,-0.4618790605702103,3.224057986252734,0.30114984604267064,0.5824510420045746,-0.525046536969556,1.430927787579856,-0.47760517435342253,-0.718878830028884,-0.6861102721985591,-0.6211353495660349,-0.6697966741024561,0.8505093952684031,2.458920809217835,-0.702470899477358,1.716496296000973,1.2011083765302808,-2.2359361102244577,-0.9537161071859821,1.90615390951366,0.998208242629227,0.5034874488366304,1.4869653023397031,-0.8183354383139178,-0.12648242619790095,0.8505093952684031,-0.11169757381838322,0.06278501041697414,-0.4149603366787841,-0.47760517435342253,-0.38389514937413705,1.8226377360704582,-0.35299894149661604,0.9371314323192231,-0.6861102721985591,0.5824510420045746,-0.8687252926726254,0.4502300599193025,-0.03834467281593642,0.3285473948164417,2.0494339813351585,-0.14130583611076566,-0.023786986148872924,0.912516307045338,1.7378829103625977,1.1303178723762042,-0.5409488224408237,1.4421793813029162,-0.5728876459442109,0.8505093952684031,0.5824510420045746,-0.8350823723193651,-0.9025689417990336,0.9738559787002006,2.4870785513620435,0.07708640378612587,-0.29170612358688064,-0.39940650424205115,3.505212800461361,3.418324905107978,-0.9537161071859821,-0.7683892185340218,-0.009266478234315357,0.8877944286969826,0.3285473948164417,1.397039326426985
| 3,069
|
Response to oxidative stress
| 23
| 94
| 2.742467
| 0.006098
|
O43169,P36639,P30519,P03915,P09601,P04083,P00374,P07237,Q969S3,P46108,Q15165,Q99720,Q15392,P39210,Q16134,Q8N0U8,P16615,Q8TED1,O60658,O75569,Q6NUK1,P04062,Q9NR28
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
0,388,10,273,26,296,43,172,301,49,436,314,194,453,458,76,333,463,90,218,220,103,121
|
1799,1471,0,2555,998,90,1144,2833,1655,218,1015,1524,478,1128,1770,43,2644,273,103,296,2963,985,939,1492,865,172,26,2706,2058,2059,1894,333,2513,1227,1495,549,1714,2306,2410,1774,2062,2877,2769,881,1958,10,1775,1715,1776,388,1331,453,2247,49,584,956,1361,2836,1171,2585,1394,1287,1135,973,543,436,780,194,458,220,1138,76,2569,463,1342,629,301,1975,2074,1916,948,1507,2043,2367,2504,314,1080,121,1464,2478,2396,646,1647,603
|
-0.3069674436057677,-0.12648242619790095,3.832785549048474,-0.7353343403528879,0.17620175517461098,2.316016170957344,0.06278501041697414,-1.0053287737997052,-0.23106749871412027,1.4981071031700752,0.16214771959355356,-0.15616800678718376,0.8129788391133055,0.07708640378612587,-0.29170612358688064,3.1076215791981863,-0.8016377952947211,1.317174902542949,2.208903801378106,1.2478186889019522,-1.30702347104922,0.19022115610960058,0.23207326087768618,-0.14130583611076566,0.30114984604267064,1.7804174649941509,3.450072877013566,-0.8687252926726254,-0.4305568818174603,-0.4305568818174603,-0.35299894149661604,1.1421774665018345,-0.702470899477358,0.005217041828054251,-0.14130583611076566,0.686061138987713,-0.26130591781680096,-0.5728876459442109,-0.637309480977452,-0.29170612358688064,-0.4305568818174603,-1.0748847085777697,-0.9195667969445095,0.28740144952661106,-0.38389514937413705,3.750749419230711,-0.29170612358688064,-0.26130591781680096,-0.29170612358688064,0.9860451122520546,-0.052939730621627525,0.8629648599038147,-0.5409488224408237,2.919735291973258,0.6474278718372324,0.21815673924788037,-0.06757235345286404,-1.0053287737997052,0.04844756194118684,-0.7518377093865654,-0.08224273671363029,-0.023786986148872924,0.07708640378612587,0.2042060940190475,0.6988808910665117,0.9001687703022228,0.3829499709628327,1.6410062740261269,0.8629648599038147,1.4981071031700752,0.07708640378612587,2.458920809217835,-0.7353343403528879,0.8505093952684031,-0.052939730621627525,0.5824510420045746,1.2245113358720499,-0.38389514937413705,-0.4305568818174603,-0.35299894149661604,0.23207326087768618,-0.14130583611076566,-0.4149603366787841,-0.6050071745182394,-0.6861102721985591,1.2011083765302808,0.11977606936216245,2.05953218036522,-0.11169757381838322,-0.6697966741024561,-0.6211353495660349,0.5562513155435278,-0.21600841862746054,0.6215260224104379
| 3,069
|
Cytochrome complex assembly
| 7
| 13
| 2.742344
| 0.0061
|
P53701,Q9Y2R0,Q69YU5,Q6DKK2,Q7KZN9,O75880,Q15070
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,9,33,100,245,246,190
|
581,246,1046,65,190,854,33,100,245,353,638,799,9
|
0.6474278718372324,1.4196539730392503,0.13393505155524324,2.570730314495249,1.6626768412225865,0.31486510761236025,3.2895471284615776,2.2383156968635576,1.430927787579856,1.0826313490872514,0.5693662452264238,0.3693979985962563,3.832785549048474
| 3,069
|
Nuclear inner membrane
| 13
| 23
| 2.740442
| 0.006136
|
Q13185,Q6ZPD9,Q8IXM6,Q5SNT2,O94901,Q14739,O75844,Q14728,P50402,Q9H1E5,Q9UH99,Q99720,Q9BTV4
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
641,357,72,523,613,272,48,754,237,85,504,314,284
|
48,613,1068,2146,969,237,1333,752,895,641,754,272,1019,523,357,72,1726,2074,314,284,85,504,1201
|
2.9457216164408178,0.5955058451096693,0.11977606936216245,-0.47760517435342253,0.2042060940190475,1.4421793813029162,-0.052939730621627525,0.4234133694254319,0.2736197563045998,0.5562513155435278,0.4234133694254319,1.3286527579296776,0.16214771959355356,0.7244341762651175,1.0706471565843538,2.4964337739427047,-0.26130591781680096,-0.4305568818174603,1.2011083765302808,1.2941497025621402,2.34488397495647,0.7625504930274744,0.03407387466120978
| 3,069
|
Mitochondrial calcium ion transport
| 8
| 17
| 2.734708
| 0.006244
|
Q10713,P21796,Q9H4I9,Q9BPX6,Q9Y277,Q8WWC4,Q8IYU8,P45880
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
226,41,11,468,117,184,546,31
|
1145,717,41,1035,31,226,546,793,184,806,1561,547,468,11,994,117,1028
|
0.06278501041697414,0.46359118404072686,3.182744358294726,0.1480588764572703,3.3623398601348073,1.4758017160295607,0.6988808910665117,0.3693979985962563,1.716496296000973,0.3558136826238937,-0.17106914307245863,0.6988808910665117,0.838026650861996,3.7357070891646837,0.19022115610960058,2.0796752385385897,0.16214771959355356
| 3,069
|
Dysphagia
| 27
| 126
| 2.732263
| 0.00629
|
P35670,O94905,Q9Y5Y5,Q14739,P00846,P09471,P03915,O60220,P07602,Q9GZY8,Q9UHX1,Q13510,Q9UBB4,P21912,Q9NR77,Q99720,Q14108,O15118,Q15067,P15586,Q01105,Q9NZJ7,P12235,O75569,P04062,P35637,Q8IZA0
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
257,265,404,272,18,395,273,406,28,412,36,46,302,176,185,314,63,192,323,320,327,205,344,218,103,232,106
|
1517,2846,1654,192,886,581,406,414,1734,1144,922,218,1015,265,2330,1525,2055,1954,18,954,273,103,1357,28,1167,2834,2532,2303,395,1894,344,320,1105,1683,1068,2357,176,2729,2768,731,1388,232,257,1991,1207,2146,2199,969,2460,2176,1450,2223,1362,1781,2491,1901,1168,2339,1364,2180,2467,327,2384,2442,2066,2784,2631,992,720,1632,1232,1312,46,63,1815,2999,1212,2635,272,323,1750,780,2389,2667,2522,1481,106,516,1788,1506,691,823,2039,745,899,2075,2233,2262,2446,476,2722,314,2190,1698,1727,1296,412,1884,1885,726,556,185,205,3023,302,2009,1438,2010,36,1319,2135,1855,1595,1950,1028,404
|
-0.15616800678718376,-1.0226379236492988,-0.23106749871412027,1.6518518344930793,0.2736197563045998,0.6474278718372324,0.9616407296721227,0.9371314323192231,-0.2764856883853633,0.06278501041697414,0.24595582673959437,1.4981071031700752,0.16214771959355356,1.3743347259546723,-0.5889246933797637,-0.15616800678718376,-0.4305568818174603,-0.38389514937413705,3.536485172574649,0.21815673924788037,1.317174902542949,2.208903801378106,-0.06757235345286404,3.418324905107978,0.04844756194118684,-1.0053287737997052,-0.718878830028884,-0.5728876459442109,0.9738559787002006,-0.35299894149661604,1.1184335679045274,1.1776090170448037,0.0913519243495543,-0.2461665934751816,0.11977606936216245,-0.6050071745182394,1.748546271130567,-0.885621875365509,-0.9195667969445095,0.4502300599193025,-0.08224273671363029,1.4534088423165563,1.397039326426985,-0.39940650424205115,0.01966376346831093,-0.47760517435342253,-0.5091886663448594,0.2042060940190475,-0.6697966741024561,-0.4933749612214743,-0.11169757381838322,-0.525046536969556,-0.06757235345286404,-0.29170612358688064,-0.6861102721985591,-0.35299894149661604,0.04844756194118684,-0.5889246933797637,-0.06757235345286404,-0.4933749612214743,-0.6697966741024561,1.1658229364583745,-0.6211353495660349,-0.6535298334803012,-0.4305568818174603,-0.9366157485523138,-0.7849891516950118,0.19022115610960058,0.46359118404072686,-0.21600841862746054,0.005217041828054251,-0.03834467281593642,2.9715906698002557,2.5983448579795256,-0.3069674436057677,-1.4547542510082334,0.01966376346831093,-0.7849891516950118,1.3286527579296776,1.1776090170448037,-0.2764856883853633,0.3829499709628327,-0.6211353495660349,-0.8183354383139178,-0.702470899477358,-0.12648242619790095,2.189211526994024,0.7498733649115101,-0.29170612358688064,-0.14130583611076566,0.5034874488366304,0.34219686706793473,-0.4149603366787841,0.43683750484696116,0.2736197563045998,-0.4305568818174603,-0.525046536969556,-0.5409488224408237,-0.6535298334803012,0.8255165059800994,-0.8687252926726254,1.2011083765302808,-0.4933749612214743,-0.2461665934751816,-0.26130591781680096,-0.023786986148872924,0.9493992521351239,-0.33761362784204135,-0.33761362784204135,0.46359118404072686,0.686061138987713,1.7057728913838957,1.5754968368419882,-1.6450079456876248,1.2245113358720499,-0.39940650424205115,-0.09695107734044302,-0.39940650424205115,3.240500487670887,-0.03834467281593642,-0.4618790605702103,-0.3222698704241627,-0.18600945144458284,-0.3684260388829964,0.16214771959355356,0.9738559787002006
| 3,069
|
Organic acid transmembrane transport
| 17
| 31
| 2.731346
| 0.006308
|
P08183,P53985,Q9Y619,P23786,Q96NB2,Q9H2J7,P41440,Q15041,O43772,Q8TDW0,P30825,Q15758,P50416,Q96QD8,O60831,Q9UBX3,Q9BQT8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
157,225,130,231,459,402,379,339,594,408,305,599,500,503,655,30,95
|
594,655,815,1524,828,848,157,759,3052,231,1090,305,955,379,500,1450,225,1134,339,599,1375,408,459,503,95,402,695,30,1383,1348,130
|
0.6344916702788778,0.5299304956557244,0.34219686706793473,-0.15616800678718376,0.3285473948164417,0.31486510761236025,1.8226377360704582,0.4099575031857863,-2.7294357611225606,1.4534088423165563,0.10558175302512113,1.2128218563732212,0.21815673924788037,1.0103454814086226,0.7625504930274744,-0.11169757381838322,1.4758017160295607,0.07708640378612587,1.1303178723762042,0.6215260224104379,-0.06757235345286404,0.9616407296721227,0.8629648599038147,0.7625504930274744,2.287002000595034,0.9738559787002006,0.5034874488366304,3.3943981532933445,-0.06757235345286404,-0.052939730621627525,1.9884673871689231
| 3,069
|
Sulfur compound transport
| 6
| 11
| 2.729937
| 0.006335
|
O15439,O00400,Q8TDW0,Q70HW3,Q8TB61,Q9UBX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
413,328,408,54,120,30
|
328,413,1134,54,1375,120,408,840,425,30,1348
|
1.1540124536294423,0.9371314323192231,0.07708640378612587,2.8410618513115837,-0.06757235345286404,2.05953218036522,0.9616407296721227,0.3285473948164417,0.9248371557106364,3.3943981532933445,-0.052939730621627525
| 3,069
|
Lipid binding
| 35
| 131
| 2.725701
| 0.006417
|
P05023,P50995,P50897,O00264,O94905,Q13045,Q99584,A6NIH7,P07602,P45880,O75477,P35610,O60313,P38435,P04083,P21796,O95772,P56589,O14773,O15173,Q14108,O15118,Q9H4L5,Q15067,P20073,Q9NZJ7,P28070,Q9Y4G8,Q8NFH5,Q8TEU7,Q8WTV0,P04062,P48739,Q8NCC3,P30536
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
509,390,2,138,265,275,535,156,28,31,286,291,414,420,296,41,45,435,53,56,63,192,325,323,321,205,334,466,336,348,98,103,492,239,114
|
1029,1797,156,138,812,1517,2639,2578,53,846,2598,192,56,1012,2819,622,2618,414,1324,1125,727,286,3047,265,2919,802,45,103,296,1034,509,866,28,1167,1327,770,2057,682,2795,2407,2271,2355,777,1988,321,2357,41,1069,1601,2332,334,888,2334,1448,114,706,291,1207,420,31,2852,2200,492,2,390,1719,893,1418,2491,3055,435,1533,1997,1261,853,275,1535,1579,1667,1634,63,2771,2815,323,2563,2283,626,2001,1264,2991,239,336,348,1615,98,1791,588,2550,2500,2233,784,535,547,1343,2006,2573,2044,1882,2914,840,609,325,1436,1729,3037,205,1027,2450,994,1274,1200,1731,905,951,2371,860,2638,466,1627,670,1705
|
0.1480588764572703,-0.3069674436057677,1.8331442437778396,1.9165081464838196,0.34219686706793473,-0.15616800678718376,-0.8016377952947211,-0.7518377093865654,2.858638405195539,0.31486510761236025,-0.7683892185340218,1.6518518344930793,2.7523611907771843,0.16214771959355356,-0.9880723020572022,0.5824510420045746,-0.7849891516950118,0.9371314323192231,-0.052939730621627525,0.07708640378612587,0.4502300599193025,1.282602169065299,-2.1718614165143197,1.3743347259546723,-1.1630471985041442,0.3558136826238937,2.9887720797510466,2.208903801378106,1.2478186889019522,0.1480588764572703,0.7498733649115101,0.30114984604267064,3.418324905107978,0.04844756194118684,-0.052939730621627525,0.39646975457854383,-0.4305568818174603,0.5034874488366304,-0.9537161071859821,-0.637309480977452,-0.5568957742270876,-0.6050071745182394,0.3829499709628327,-0.39940650424205115,1.1776090170448037,-0.6050071745182394,3.182744358294726,0.11977606936216245,-0.2009891400311259,-0.5889246933797637,1.1421774665018345,0.2736197563045998,-0.5889246933797637,-0.11169757381838322,2.0796752385385897,0.47692102554906757,1.2710312196614248,0.01966376346831093,0.9248371557106364,3.3623398601348073,-1.0226379236492988,-0.5091886663448594,0.7878204493186719,3.832785549048474,0.9860451122520546,-0.26130591781680096,0.2736197563045998,-0.09695107734044302,-0.6861102721985591,-3.0675485201008637,0.9001687703022228,-0.15616800678718376,-0.39940650424205115,-0.009266478234315357,0.31486510761236025,1.317174902542949,-0.15616800678718376,-0.18600945144458284,-0.23106749871412027,-0.21600841862746054,2.5983448579795256,-0.9195667969445095,-0.970868186256457,1.1776090170448037,-0.7353343403528879,-0.5568957742270876,0.5824510420045746,-0.39940650424205115,-0.009266478234315357,-1.398902708781335,1.4421793813029162,1.1421774665018345,1.1065244490846795,-0.2009891400311259,2.248086156847928,-0.29170612358688064,0.6474278718372324,-0.718878830028884,-0.6861102721985591,-0.525046536969556,0.3829499709628327,0.7116718601694995,0.6988808910665117,-0.052939730621627525,-0.39940650424205115,-0.7353343403528879,-0.4149603366787841,-0.33761362784204135,-1.145304659012404,0.3285473948164417,0.6085307928083136,1.1776090170448037,-0.09695107734044302,-0.26130591781680096,-1.9023024113787137,1.5754968368419882,0.16214771959355356,-0.6535298334803012,0.19022115610960058,-0.009266478234315357,0.03407387466120978,-0.26130591781680096,0.2736197563045998,0.23207326087768618,-0.6050071745182394,0.31486510761236025,-0.7849891516950118,0.8505093952684031,-0.2009891400311259,0.5299304956557244,-0.2461665934751816
| 3,069
|
Purine nucleotide transport
| 9
| 13
| 2.721282
| 0.006503
|
O15439,O00400,Q6NUK1,Q8TDW0,P12235,Q08722,Q8TB61,P41440,P12236
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
413,328,220,408,344,317,120,379,439
|
328,413,521,816,344,439,379,317,220,1375,120,408,934
|
1.1540124536294423,0.9371314323192231,0.7244341762651175,0.34219686706793473,1.1184335679045274,0.8877944286969826,1.0103454814086226,1.1893707968069043,1.4981071031700752,-0.06757235345286404,2.05953218036522,0.9616407296721227,0.24595582673959437
| 3,069
|
Horizontal nystagmus
| 6
| 24
| 2.716366
| 0.0066
|
Q9H061,P04062,Q9NZJ7,P00846,O14773,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
34,103,205,18,53,28
|
2872,1517,53,2598,414,265,1770,18,103,28,1068,1207,2149,1362,1901,1112,2284,1458,2721,34,2047,632,205,1319
|
-1.0748847085777697,-0.15616800678718376,2.858638405195539,-0.7683892185340218,0.9371314323192231,1.3743347259546723,-0.29170612358688064,3.536485172574649,2.208903801378106,3.418324905107978,0.11977606936216245,0.01966376346831093,-0.47760517435342253,-0.06757235345286404,-0.35299894149661604,0.0913519243495543,-0.5568957742270876,-0.11169757381838322,-0.8687252926726254,3.2895471284615776,-0.4149603366787841,0.5824510420045746,1.5754968368419882,-0.03834467281593642
| 3,069
|
Abnormality of head blood vessel
| 9
| 25
| 2.716057
| 0.006606
|
P21964,Q9NZJ7,Q13510,P00846,P16278,P03915,P10619,P17900,P07602
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
204,205,46,18,83,273,25,123,28
|
3042,1654,2196,18,273,303,28,1104,25,2457,83,123,2357,204,889,707,2517,2202,46,1479,1874,2073,205,2791,447
|
-2.004463803227854,-0.23106749871412027,-0.5091886663448594,3.536485172574649,1.317174902542949,1.2128218563732212,3.418324905107978,0.0913519243495543,3.4579825093765058,-0.6697966741024561,2.37360689336414,2.039317917817865,-0.6050071745182394,1.5864673909793765,0.2736197563045998,0.47692102554906757,-0.702470899477358,-0.5091886663448594,2.9715906698002557,-0.12648242619790095,-0.33761362784204135,-0.4305568818174603,1.5754968368419882,-0.9366157485523138,0.8877944286969826
| 3,069
|
Chemical homeostasis
| 39
| 178
| 2.715309
| 0.006621
|
Q8N5M9,P35670,Q9P035,Q9Y6C9,P50897,P30519,Q9H4I9,Q9HD47,P62942,O75503,P49366,Q96A33,P09601,Q8N511,Q93050,P52789,P35610,Q6P4Q7,Q8WWC4,P42785,Q15067,O15118,O15260,P16615,Q9Y6M7,Q96AQ8,P51572,P53985,Q8WTV0,Q8NF37,Q9NQC3,P04062,Q13586,Q96PU5,P30536,Q8TAD4,O75880,Q9HD20,Q8NEW0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,257,131,259,2,10,11,15,17,146,274,149,26,27,161,163,291,307,184,59,323,192,201,333,342,349,351,225,98,228,102,103,364,366,114,116,246,125,126
|
1833,2872,2596,572,1567,2885,192,2170,1012,201,2555,581,2703,1126,864,146,246,2898,953,717,1525,1656,2300,828,1128,604,103,2963,1088,509,1042,1493,1129,2110,2301,1104,1327,770,2197,2057,26,2706,3043,2964,2512,2112,879,2485,333,1529,2822,2486,1105,2782,1446,1251,597,2958,1069,2306,2410,2709,888,2893,2062,2361,10,114,657,943,291,257,2537,2064,2247,59,2199,584,274,2,1417,2030,351,585,163,225,1866,1781,1363,790,2691,17,752,2836,598,779,991,2544,720,1367,1394,2633,3066,1579,364,2340,1869,375,533,323,2416,1750,1968,514,1150,762,467,1399,307,1190,1375,2696,546,516,2524,27,129,524,793,126,228,116,98,184,1316,161,149,349,1460,2074,1916,366,2043,873,2504,934,468,1509,1173,2992,1885,1346,1699,11,1542,1198,125,15,102,2396,2397,131,3023,3011,2101,1409,994,1009,904,1122,1300,1028,670,2373,2761,1301,259,342
|
-0.3222698704241627,-1.0748847085777697,-0.7683892185340218,0.6603347615792099,-0.18600945144458284,-1.0924078528835213,1.6518518344930793,-0.4933749612214743,0.16214771959355356,1.5974169115678218,-0.7353343403528879,0.6474278718372324,-0.8687252926726254,0.07708640378612587,0.30114984604267064,1.874978181937071,1.4196539730392503,-1.127617485810929,0.21815673924788037,0.46359118404072686,-0.15616800678718376,-0.23106749871412027,-0.5728876459442109,0.3285473948164417,0.07708640378612587,0.6085307928083136,2.208903801378106,-1.30702347104922,0.10558175302512113,0.7498733649115101,0.13393505155524324,-0.14130583611076566,0.07708640378612587,-0.4618790605702103,-0.5728876459442109,0.0913519243495543,-0.052939730621627525,0.39646975457854383,-0.5091886663448594,-0.4305568818174603,3.450072877013566,-0.8687252926726254,-2.004463803227854,-1.30702347104922,-0.702470899477358,-0.4618790605702103,0.28740144952661106,-0.6861102721985591,1.1421774665018345,-0.15616800678718376,-0.9880723020572022,-0.6861102721985591,0.0913519243495543,-0.9366157485523138,-0.11169757381838322,-0.009266478234315357,0.6215260224104379,-1.2888250976967754,0.11977606936216245,-0.5728876459442109,-0.637309480977452,-0.8687252926726254,0.2736197563045998,-1.1099853317350328,-0.4305568818174603,-0.6050071745182394,3.750749419230711,2.0796752385385897,0.5299304956557244,0.23207326087768618,1.2710312196614248,1.397039326426985,-0.718878830028884,-0.4305568818174603,-0.5409488224408237,2.7074905411166843,-0.5091886663448594,0.6474278718372324,1.317174902542949,3.832785549048474,-0.09695107734044302,-0.4149603366787841,1.0945904112546285,0.6474278718372324,1.8015665931551217,1.4758017160295607,-0.33761362784204135,-0.29170612358688064,-0.06757235345286404,0.3693979985962563,-0.8518788914948365,3.5598281788847492,0.4234133694254319,-1.0053287737997052,0.6215260224104379,0.3829499709628327,0.19022115610960058,-0.718878830028884,0.46359118404072686,-0.06757235345286404,-0.08224273671363029,-0.7849891516950118,-8.249623135437572,-0.18600945144458284,1.0466029531902257,-0.5889246933797637,-0.33761362784204135,1.0224569394488752,0.7116718601694995,1.1776090170448037,-0.637309480977452,-0.2764856883853633,-0.38389514937413705,0.7498733649115101,0.06278501041697414,0.4099575031857863,0.838026650861996,-0.08224273671363029,1.2128218563732212,0.03407387466120978,-0.06757235345286404,-0.8518788914948365,0.6988808910665117,0.7498733649115101,-0.702470899477358,3.442152330866641,1.9884673871689231,0.7244341762651175,0.3693979985962563,2.0088619004284114,1.4646162582043338,2.0796752385385897,2.248086156847928,1.716496296000973,-0.03834467281593642,1.8121118765241035,1.8645483697136485,1.1065244490846795,-0.11169757381838322,-0.4305568818174603,-0.35299894149661604,1.0466029531902257,-0.4149603366787841,0.30114984604267064,-0.6861102721985591,0.24595582673959437,0.838026650861996,-0.14130583611076566,0.04844756194118684,-1.398902708781335,-0.33761362784204135,-0.052939730621627525,-0.2461665934751816,3.7357070891646837,-0.15616800678718376,0.03407387466120978,2.0190319417003906,3.598523543210219,2.228528522830431,-0.6211353495660349,-0.6211353495660349,1.9679998631297153,-1.6450079456876248,-1.5300902971981285,-0.446196376754283,-0.08224273671363029,0.19022115610960058,0.17620175517461098,0.2736197563045998,0.0913519243495543,-0.023786986148872924,0.16214771959355356,0.5299304956557244,-0.6050071745182394,-0.9025689417990336,-0.023786986148872924,1.397039326426985,1.1303178723762042
| 3,069
|
Steroid metabolic process
| 22
| 62
| 2.709984
| 0.006729
|
P05023,O94905,Q14739,P16435,Q14534,P38571,O75477,P35610,P38435,O95470,Q13510,P37268,Q9H4L5,O15118,Q15800,O14975,Q15392,Q16850,Q8WTV0,P04062,O14734,P30536
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
509,265,272,154,155,416,286,291,420,162,46,433,325,192,66,573,194,84,98,103,481,114
|
481,573,192,286,265,162,967,103,509,2921,2059,1358,2485,154,1069,1601,2688,2143,1090,114,943,291,433,420,416,2118,1359,1416,2176,1230,1933,3019,1997,2493,1747,46,2314,155,272,945,194,2566,2258,1969,66,84,1018,1399,690,98,2074,784,2722,836,1344,591,325,1143,3011,668,2808,1319
|
0.8004135279398286,0.6603347615792099,1.6518518344930793,1.282602169065299,1.3743347259546723,1.8015665931551217,0.2042060940190475,2.208903801378106,0.7498733649115101,-1.1630471985041442,-0.4305568818174603,-0.06757235345286404,-0.6861102721985591,1.843631471229452,0.11977606936216245,-0.2009891400311259,-0.8518788914948365,-0.47760517435342253,0.10558175302512113,2.0796752385385897,0.23207326087768618,1.2710312196614248,0.9001687703022228,0.9248371557106364,0.9371314323192231,-0.4618790605702103,-0.06757235345286404,-0.09695107734044302,-0.4933749612214743,0.005217041828054251,-0.3684260388829964,-1.6064422764023063,-0.39940650424205115,-0.6861102721985591,-0.2764856883853633,2.9715906698002557,-0.5728876459442109,1.843631471229452,1.3286527579296776,0.23207326087768618,1.6410062740261269,-0.7353343403528879,-0.5409488224408237,-0.38389514937413705,2.5522463606903325,2.37360689336414,0.16214771959355356,-0.08224273671363029,0.5034874488366304,2.248086156847928,-0.4305568818174603,0.3829499709628327,-0.8687252926726254,0.3285473948164417,-0.052939730621627525,0.6474278718372324,1.1776090170448037,0.07708640378612587,-1.5300902971981285,0.5299304956557244,-0.9537161071859821,-0.03834467281593642
| 3,069
|
SLC superfamily of solute carriers
| 12
| 47
| 3.371839
| 0.000747
|
Q6NT16,Q9BQT8,Q9H2V7,Q70HW3,O43772,Q8TAD4,Q99808,Q6N075,Q8IXU6,P30825,P41440,P53985
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
1,72,142,105,13,78,82,49,19,53,23,91
|
2924,300,13,1260,1956,1809,2092,2182,689,532,1156,2404,53,23,2237,91,1525,1474,837,671,489,49,1,1658,2678,105,19,2983,78,1667,520,1840,82,72,1188,2389,142,712,2125,1996,2590,1252,1850,203,1449,400,1564
|
-1.2346016602834036,0.8931505508985713,4.970267139748916,0.05351387697527753,-0.25603753973957905,-0.18427244054683523,-0.32800834772899334,-0.37610541469729714,0.38293496406007926,0.522950800501484,0.10081598985120394,-0.49676620728557386,2.6422040422429265,4.02275923887349,-0.40018942775227584,1.9123959679548161,-0.06510924961463846,-0.04134201322447215,0.28921102773708735,0.40631795439279017,0.5694744024903953,2.773483764219382,7.921702806360599,-0.11270866851683332,-0.7155242386586748,1.688457034793547,4.234837774349021,-1.588331377422339,2.0905801244850664,-0.11270866851683332,0.546221743136157,-0.18427244054683523,2.0683529149150766,2.179360380668593,0.10081598985120394,-0.47258553589199437,1.4405014163205085,0.38293496406007926,-0.32800834772899334,-0.25603753973957905,-0.618042899175275,0.0771753025605692,-0.18427244054683523,1.145146616611409,-0.017596227567052123,0.7086124029290911,-0.06510924961463846
| 3,067
|
Oxidoreductase activity acting on the ch ch group of donors
| 11
| 31
| 2.958223
| 0.003094
|
P50336,P36551,Q9BY49,Q15067,Q15392,Q14914,Q8N8N7,Q8N4Q0,Q14739,O15254,Q9H7Z7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,258,201,140,77,150,22,24,182,30,63
|
30,2915,1513,1266,2701,2059,831,2543,258,2143,2478,982,64,1921,182,150,140,77,514,1931,2342,24,22,1605,883,201,63,2261,2430,1011,289
|
3.63867524824419,-1.2095852996870387,-0.06510924961463846,0.05351387697527753,-0.7644228326298534,-0.3039949440411763,0.28921102773708735,-0.5937371293542618,0.9850140031000338,-0.35204511338992117,-0.5452016332533733,0.19517407509175846,2.312151123677215,-0.2320932034861173,1.2135360793065495,1.3952290840127508,1.4405014163205085,2.0905801244850664,0.546221743136157,-0.2320932034861173,-0.4484293059503235,3.980233949280333,4.044008051312098,-0.08889808473863031,0.2657314452879552,1.145146616611409,2.356315196972746,-0.40018942775227584,-0.49676620728557386,0.19517407509175846,0.9391154562432038
| 3,067
|
Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor
| 7
| 14
| 2.945398
| 0.003225
|
Q9BY49,Q15392,Q8N8N7,Q14739,Q8N4Q0,Q14914,Q9H7Z7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
201,77,22,182,24,150,63
|
831,2143,2478,1921,182,150,77,24,22,883,201,63,1011,289
|
0.28921102773708735,-0.35204511338992117,-0.5452016332533733,-0.2320932034861173,1.2135360793065495,1.3952290840127508,2.0905801244850664,3.980233949280333,4.044008051312098,0.2657314452879552,1.145146616611409,2.356315196972746,0.19517407509175846,0.9391154562432038
| 3,067
|
mRNA processing factor
| 34
| 75
| 2.858507
| 0.004256
|
Q93062,Q01844,Q15233,P98179,Q96PK6,P35637,Q96SI9,Q13243,Q13595,Q9HCS7,P09012,Q16629,P19338,P23246,P84103,Q96PU8,Q92804,Q8IY67,Q96E39,P62312,Q13242,O95104,Q8WXF1,Q14011,Q9BWF3,O75525,Q9BZJ0,O75494,P38159,Q8IWZ8,O75934,P62995,Q96KR1,Q07955
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
397,645,270,268,146,149,295,668,537,713,690,327,445,568,571,736,79,81,735,599,340,95,495,93,502,354,629,108,109,110,237,486,383,260
|
1397,1151,1568,2926,1204,108,354,789,237,1753,95,1208,2644,1023,690,1638,445,568,721,149,109,1272,2148,599,2807,1650,1972,486,571,268,645,1423,260,802,869,2023,1534,1076,1327,1774,340,668,1034,537,93,2781,270,2518,907,1037,1082,2713,327,1929,110,1288,81,2208,1782,495,79,397,735,1295,813,383,146,736,295,502,629,1299,713,1142,892
|
-0.017596227567052123,0.10081598985120394,-0.08889808473863031,-1.2346016602834036,0.0771753025605692,1.665987090283156,0.7779431050658644,0.31267104849579785,1.0537389733278402,-0.1603956915349074,1.8229845236200364,0.0771753025605692,-0.691114745586028,0.17161498562321423,0.38293496406007926,-0.11270866851683332,0.6159253041543369,0.4996614648715897,0.3595328957429135,1.3952290840127508,1.6435030564502273,0.05351387697527753,-0.35204511338992117,0.4763536252951922,-0.9117717140860812,-0.11270866851683332,-0.25603753973957905,0.5694744024903953,0.4996614648715897,0.9620729791073839,0.4296819841917649,-0.017596227567052123,0.9850140031000338,0.31267104849579785,0.2657314452879552,-0.28000473103222856,-0.06510924961463846,0.14803569668995656,0.029831574171165644,-0.1603956915349074,0.8010187077276009,0.40631795439279017,0.17161498562321423,0.522950800501484,1.8900633397760067,-0.8625447160545955,0.9620729791073839,-0.5694567741728175,0.24223217662498808,0.17161498562321423,0.14803569668995656,-0.7644228326298534,0.8471185516552913,-0.2320932034861173,1.6435030564502273,0.05351387697527753,2.0683529149150766,-0.37610541469729714,-0.1603956915349074,0.5694744024903953,2.0905801244850664,0.7086124029290911,0.3595328957429135,0.05351387697527753,0.31267104849579785,0.7317400515807754,1.4178726825545127,0.3595328957429135,0.9161413439901327,0.5694744024903953,0.4530271695640074,0.05351387697527753,0.38293496406007926,0.12443607605412232,0.2657314452879552
| 3,067
|
mRNA splicing factor
| 31
| 60
| 2.797616
| 0.005148
|
Q93062,Q01844,Q15233,P98179,Q96PK6,P35637,Q13243,Q13595,Q9HCS7,P09012,Q16629,P19338,P23246,P84103,Q96PU8,Q92804,Q8IY67,Q96E39,P62312,Q14011,Q13242,Q8WXF1,Q9BWF3,O75525,Q9BZJ0,O75494,P38159,Q8IWZ8,O75934,P62995,Q07955
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
397,645,270,268,146,149,668,537,713,690,327,445,568,571,736,79,81,735,599,93,340,495,502,354,629,108,109,110,237,486,260
|
1151,1568,2926,1204,108,354,789,237,1753,2644,1023,690,1638,445,568,721,149,109,2148,599,2807,1972,486,571,268,645,1423,260,802,869,1534,1076,340,668,1034,537,93,2781,270,2518,907,1037,1082,327,1929,110,1288,81,1782,495,79,397,735,146,736,502,629,713,1142,892
|
0.10081598985120394,-0.08889808473863031,-1.2346016602834036,0.0771753025605692,1.665987090283156,0.7779431050658644,0.31267104849579785,1.0537389733278402,-0.1603956915349074,-0.691114745586028,0.17161498562321423,0.38293496406007926,-0.11270866851683332,0.6159253041543369,0.4996614648715897,0.3595328957429135,1.3952290840127508,1.6435030564502273,-0.35204511338992117,0.4763536252951922,-0.9117717140860812,-0.25603753973957905,0.5694744024903953,0.4996614648715897,0.9620729791073839,0.4296819841917649,-0.017596227567052123,0.9850140031000338,0.31267104849579785,0.2657314452879552,-0.06510924961463846,0.14803569668995656,0.8010187077276009,0.40631795439279017,0.17161498562321423,0.522950800501484,1.8900633397760067,-0.8625447160545955,0.9620729791073839,-0.5694567741728175,0.24223217662498808,0.17161498562321423,0.14803569668995656,0.8471185516552913,-0.2320932034861173,1.6435030564502273,0.05351387697527753,2.0683529149150766,-0.1603956915349074,0.5694744024903953,2.0905801244850664,0.7086124029290911,0.3595328957429135,1.4178726825545127,0.3595328957429135,0.5694744024903953,0.4530271695640074,0.38293496406007926,0.12443607605412232,0.2657314452879552
| 3,067
|
Protein kinase, ATP binding site [IPR017441]
| 6
| 38
| 2.784192
| 0.005366
|
Q96GD4,Q14004,P49840,P49841,P06493,P24941
|
Sequence
|
InterPro Binding site
|
interpro_binding_site
|
65,38,11,46,25,26
|
2670,2277,2007,25,403,1698,366,2598,1872,2282,26,2756,1068,2685,1966,1818,11,46,722,88,1976,1222,2414,1328,392,2244,38,1713,1540,426,994,1330,2783,65,1676,1488,711,965
|
-0.7155242386586748,-0.4242973311338641,-0.28000473103222856,3.95895741112925,0.6854672060130802,-0.13654115282560736,0.7548502524793712,-0.6423742870091806,-0.2081715578352066,-0.4242973311338641,3.9163763942062166,-0.83797308570648,0.14803569668995656,-0.7399601945456966,-0.25603753973957905,-0.18427244054683523,5.157748552028619,2.9478894554497037,0.3595328957429135,1.9570211264778132,-0.25603753973957905,0.0771753025605692,-0.49676620728557386,0.029831574171165644,0.7086124029290911,-0.40018942775227584,3.273018749025682,-0.13654115282560736,-0.06510924961463846,0.6623043592342954,0.19517407509175846,0.029831574171165644,-0.8625447160545955,2.312151123677215,-0.11270866851683332,-0.04134201322447215,0.38293496406007926,0.21871309573559264
| 3,067
|
MFS transporter superfamily [IPR036259]
| 7
| 11
| 2.774613
| 0.005527
|
Q6NT16,Q14728,Q9H2V7,Q99808,Q6N075,P41440,P53985
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
1,68,142,82,49,23,91
|
2924,532,23,91,68,187,49,1,1001,82,142
|
-1.2346016602834036,0.522950800501484,4.02275923887349,1.9123959679548161,2.2679375802329096,1.1907552610982108,2.773483764219382,7.921702806360599,0.19517407509175846,2.0683529149150766,1.4405014163205085
| 3,067
|
Vascular process in circulatory system
| 8
| 31
| 2.76237
| 0.005738
|
Q9HB40,P53985,P08183,O15439,Q99808,P30825,P41440,P42892
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
103,91,12,170,82,53,23,59
|
1102,170,2952,2670,1021,1960,2567,12,532,2183,1065,53,23,59,834,91,1525,2629,1772,905,392,953,489,187,2678,1242,1840,82,103,2127,1850
|
0.12443607605412232,1.2363013365837792,-1.3601684318707938,-0.7155242386586748,0.17161498562321423,-0.25603753973957905,-0.618042899175275,5.095325835237832,0.522950800501484,-0.37610541469729714,0.14803569668995656,2.6422040422429265,4.02275923887349,2.5544523677537962,0.28921102773708735,1.9123959679548161,-0.06510924961463846,-0.6667314992911156,-0.1603956915349074,0.24223217662498808,0.7086124029290911,0.21871309573559264,0.5694744024903953,1.1907552610982108,-0.7155242386586748,0.0771753025605692,-0.18427244054683523,2.0683529149150766,1.710912956736977,-0.32800834772899334,-0.18427244054683523
| 3,067
|
Protein transmembrane transport
| 6
| 25
| 2.756909
| 0.005835
|
Q9NS69,Q99595,O75381,O95831,Q15629,O60830
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
67,4,171,14,151,28
|
2736,744,28,2913,171,1692,14,718,1812,2183,186,2410,2240,2608,2485,151,2205,1724,1608,4,2588,67,1390,362,1198
|
-0.8134290501122715,0.33611163062394667,3.702904303597902,-1.2095852996870387,1.2363013365837792,-0.13654115282560736,4.6563469220776925,0.3595328957429135,-0.18427244054683523,-0.37610541469729714,1.1907552610982108,-0.49676620728557386,-0.40018942775227584,-0.6423742870091806,-0.5452016332533733,1.3725705462368945,-0.37610541469729714,-0.13654115282560736,-0.08889808473863031,6.167780078048627,-0.618042899175275,2.290050562055856,0.006128253475181141,0.7779431050658644,0.10081598985120394
| 3,067
|
Cholesterol metabolism
| 8
| 20
| 2.723088
| 0.006467
|
P35610,Q15392,P37268,Q16850,Q14739,Q9UBM7,Q15126,Q9UHB6
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
102,77,139,50,182,289,246,127
|
291,828,1863,1694,1263,1157,1316,102,139,1771,2710,2779,182,246,77,1657,538,50,289,127
|
0.9161413439901327,0.28921102773708735,-0.2081715578352066,-0.13654115282560736,0.05351387697527753,0.10081598985120394,0.029831574171165644,1.7333549222805171,1.4405014163205085,-0.1603956915349074,-0.7644228326298534,-0.8625447160545955,1.2135360793065495,1.030846911961832,2.0905801244850664,-0.11270866851683332,0.522950800501484,2.7297697351237553,0.9391154562432038,1.5082991632477938
| 3,067
|
Distal muscle weakness
| 10
| 62
| 2.697596
| 0.006984
|
Q9Y4W6,P00846,P36551,Q9NR77,Q9BQT8,O95831,Q99720,P35637,P41440,P39210
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
298,36,258,8,72,14,17,149,23,214
|
2318,1859,2699,1863,2322,1810,14,36,898,2399,461,1461,2624,482,2055,2368,463,794,1918,149,258,214,795,2325,23,1703,2016,1584,693,2237,2104,2145,1821,2961,1884,1708,620,765,2794,2248,953,2073,2520,1544,1234,772,1376,958,330,1092,777,17,72,1730,8,2531,1502,1053,298,2269,1563,660
|
-0.4484293059503235,-0.2081715578352066,-0.7644228326298534,-0.2081715578352066,-0.4484293059503235,-0.18427244054683523,4.6563469220776925,3.273018749025682,0.24223217662498808,-0.49676620728557386,0.5927088870625801,-0.04134201322447215,-0.6667314992911156,0.5694744024903953,-0.3039949440411763,-0.47258553589199437,0.5927088870625801,0.31267104849579785,-0.2320932034861173,1.3952290840127508,0.9850140031000338,1.0994747445642425,0.31267104849579785,-0.4484293059503235,4.02275923887349,-0.13654115282560736,-0.28000473103222856,-0.08889808473863031,0.38293496406007926,-0.40018942775227584,-0.32800834772899334,-0.35204511338992117,-0.18427244054683523,-1.410627524712207,-0.2081715578352066,-0.13654115282560736,0.4530271695640074,0.33611163062394667,-0.8871441784646263,-0.40018942775227584,0.21871309573559264,-0.3039949440411763,-0.5694567741728175,-0.06510924961463846,0.0771753025605692,0.33611163062394667,0.006128253475181141,0.21871309573559264,0.8471185516552913,0.14803569668995656,0.33611163062394667,4.2982861261730845,2.179360380668593,-0.13654115282560736,5.4067425730737195,-0.5694567741728175,-0.04134201322447215,0.17161498562321423,0.9161413439901327,-0.40018942775227584,-0.06510924961463846,0.4296819841917649
| 3,067
|
Predicted secreted proteins
| 8
| 49
| 2.690095
| 0.007143
|
O60888,Q8WUJ1,O75718,Q9HB40,Q15165,Q9UMX5,P80303,P14174
|
Functions
|
Protein Atlas Protein class
|
protein_atlas_protein_class
|
0,3,6,103,40,43,45,55
|
1104,2952,0,6,1021,790,1960,1354,2474,1355,250,2402,55,1756,2600,3026,1967,2144,2103,3017,45,2378,2988,302,904,1075,1223,839,425,40,413,437,395,2211,876,3,1178,2345,2656,1132,419,583,963,2854,143,103,1140,43,2129
|
0.12443607605412232,-1.3601684318707938,9.125649574112689,5.592772581581793,0.17161498562321423,0.31267104849579785,-0.25603753973957905,0.006128253475181141,-0.5452016332533733,0.006128253475181141,1.0079386178201262,-0.49676620728557386,2.5983516406440144,-0.1603956915349074,-0.6423742870091806,-2.1586705530091552,-0.25603753973957905,-0.35204511338992117,-0.32800834772899334,-2.0274970719938357,3.0131088924359384,-0.47258553589199437,-1.613861950804346,0.8931505508985713,0.24223217662498808,0.14803569668995656,0.0771753025605692,0.28921102773708735,0.6623043592342954,3.229806250235141,0.6854672060130802,0.6391237598897699,0.7086124029290911,-0.37610541469729714,0.2657314452879552,7.040498432373202,0.10081598985120394,-0.4484293059503235,-0.691114745586028,0.12443607605412232,0.6854672060130802,0.4996614648715897,0.21871309573559264,-0.9858252312843699,1.4405014163205085,1.710912956736977,0.12443607605412232,3.164908831693504,-0.32800834772899334
| 3,067
|
transporter
| 11
| 61
| 2.689929
| 0.007147
|
Q99595,Q9Y619,Q9NR77,Q567V2,Q9H2V7,O43772,Q99808,Q6N075,P41440,P53985,O60830
|
Functions
|
Panther Protein class
|
panther_protein_class
|
4,203,8,9,142,13,82,49,23,91,28
|
443,1201,1566,2273,2360,1259,388,744,1801,13,1751,28,2006,1811,979,2982,214,23,2758,759,985,1524,1031,2237,91,1275,1969,3023,1276,2608,3063,509,1714,1479,9,49,810,910,2210,604,2166,2116,2037,359,2457,677,4,2922,82,2785,2863,142,1844,1345,8,2619,2592,888,362,2269,203
|
0.6159253041543369,0.0771753025605692,-0.08889808473863031,-0.4242973311338641,-0.47258553589199437,0.05351387697527753,0.7086124029290911,0.33611163062394667,-0.18427244054683523,4.970267139748916,-0.1603956915349074,3.702904303597902,-0.28000473103222856,-0.18427244054683523,0.19517407509175846,-1.588331377422339,1.0994747445642425,4.02275923887349,-0.83797308570648,0.33611163062394667,0.19517407509175846,-0.06510924961463846,0.17161498562321423,-0.40018942775227584,1.9123959679548161,0.05351387697527753,-0.25603753973957905,-2.132366594669272,0.05351387697527753,-0.6423742870091806,-6.191987398232292,0.546221743136157,-0.13654115282560736,-0.04134201322447215,5.303129290746076,2.773483764219382,0.31267104849579785,0.24223217662498808,-0.37610541469729714,0.4763536252951922,-0.35204511338992117,-0.32800834772899334,-0.28000473103222856,0.7779431050658644,-0.5209715091499124,0.40631795439279017,6.167780078048627,-1.2095852996870387,2.0683529149150766,-0.8625447160545955,-1.0105675513507224,1.4405014163205085,-0.18427244054683523,0.029831574171165644,5.4067425730737195,-0.6423742870091806,-0.618042899175275,0.2657314452879552,0.7779431050658644,-0.40018942775227584,1.145146616611409
| 3,067
|
Abnormality of the calf
| 6
| 55
| 2.673267
| 0.007512
|
O75718,Q9NR77,Q13126,O95831,Q32P28,Q96HY6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
6,8,10,14,48,51
|
1799,2904,1456,2397,1205,6,1755,14,1063,2507,2401,2956,2907,936,366,2598,2599,2366,2407,1214,1917,2685,833,942,61,1879,2941,1119,1592,1976,10,949,2934,1595,2654,2069,1598,48,1083,2679,1781,51,2123,1993,8,351,1899,852,263,2431,1498,1255,2129,1197,203
|
-0.18427244054683523,-1.1846005429298558,-0.04134201322447215,-0.49676620728557386,0.0771753025605692,5.592772581581793,-0.1603956915349074,4.6563469220776925,0.14803569668995656,-0.5694567741728175,-0.49676620728557386,-1.3853810437648244,-1.1846005429298558,0.21871309573559264,0.7548502524793712,-0.6423742870091806,-0.6423742870091806,-0.47258553589199437,-0.49676620728557386,0.0771753025605692,-0.2320932034861173,-0.7399601945456966,0.28921102773708735,0.21871309573559264,2.5105058405134244,-0.2081715578352066,-1.2847304228470318,0.12443607605412232,-0.08889808473863031,-0.25603753973957905,5.282383753260578,0.21871309573559264,-1.2596499307860836,-0.08889808473863031,-0.691114745586028,-0.3039949440411763,-0.08889808473863031,2.795323733143928,0.14803569668995656,-0.7155242386586748,-0.1603956915349074,2.7297697351237553,-0.32800834772899334,-0.25603753973957905,5.4067425730737195,0.8010187077276009,-0.2081715578352066,0.28921102773708735,0.9850140031000338,-0.49676620728557386,-0.04134201322447215,0.0771753025605692,-0.32800834772899334,0.10081598985120394,1.145146616611409
| 3,067
|
Lipid localization
| 17
| 72
| 2.669195
| 0.007603
|
P35610,Q86Y82,O15118,Q9H2V7,P08183,O43772,O15439,Q99720,P23786,P33121,P28288,P30536,P14174,Q9H4L5,O15260,Q8WTV0,Q9UHB6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
102,71,291,142,12,13,170,17,147,148,205,85,55,287,57,27,127
|
1621,3049,300,291,57,170,13,1260,1906,1152,2276,1754,2897,1909,1263,1354,1355,1110,2868,2441,12,532,55,2844,2096,2058,147,205,1701,85,148,102,2758,2674,1771,1222,2731,905,1283,1122,2074,1886,2930,468,2678,1932,71,2211,27,546,2658,1893,2851,2661,17,582,2309,2310,2899,142,287,2500,3013,885,1996,741,127,888,2950,2466,2317,2050
|
-0.11270866851683332,-2.718584481499948,0.8931505508985713,0.9161413439901327,2.5764078869149727,1.2363013365837792,4.970267139748916,0.05351387697527753,-0.2320932034861173,0.10081598985120394,-0.4242973311338641,-0.1603956915349074,-1.1347246437212606,-0.2320932034861173,0.05351387697527753,0.006128253475181141,0.006128253475181141,0.12443607605412232,-1.0353392113150601,-0.5209715091499124,5.095325835237832,0.522950800501484,2.5983516406440144,-0.9858252312843699,-0.32800834772899334,-0.3039949440411763,1.3952290840127508,1.1223186256989308,-0.13654115282560736,2.0015932231890448,1.3952290840127508,1.7333549222805171,-0.83797308570648,-0.7155242386586748,-0.1603956915349074,0.0771753025605692,-0.7889123757164783,0.24223217662498808,0.05351387697527753,0.12443607605412232,-0.3039949440411763,-0.2081715578352066,-1.2346016602834036,0.5927088870625801,-0.7155242386586748,-0.2320932034861173,2.179360380668593,-0.37610541469729714,3.8737579156642066,0.522950800501484,-0.691114745586028,-0.2081715578352066,-0.9858252312843699,-0.691114745586028,4.2982861261730845,0.4996614648715897,-0.4242973311338641,-0.4242973311338641,-1.1347246437212606,1.4405014163205085,0.9391154562432038,-0.5452016332533733,-1.9492158873280787,0.2657314452879552,-0.25603753973957905,0.3595328957429135,1.5082991632477938,0.2657314452879552,-1.3349893470843226,-0.5209715091499124,-0.4242973311338641,-0.28000473103222856
| 3,067
|
Organic acid transmembrane transporter activity
| 7
| 22
| 2.66654
| 0.007664
|
Q9Y619,Q9BQT8,P08183,O15439,P30825,P41440,P53985
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
203,72,12,170,53,23,91
|
300,170,1956,2092,12,689,53,23,2237,91,837,489,2678,520,1840,72,2389,712,2590,1252,1850,203
|
0.8931505508985713,1.2363013365837792,-0.25603753973957905,-0.32800834772899334,5.095325835237832,0.38293496406007926,2.6422040422429265,4.02275923887349,-0.40018942775227584,1.9123959679548161,0.28921102773708735,0.5694744024903953,-0.7155242386586748,0.546221743136157,-0.18427244054683523,2.179360380668593,-0.47258553589199437,0.38293496406007926,-0.618042899175275,0.0771753025605692,-0.18427244054683523,1.145146616611409
| 3,067
|
Anion transport
| 15
| 73
| 2.651391
| 0.008016
|
Q14728,Q9Y619,Q9BQT8,Q8TDW0,Q9H0H5,P08183,O15439,Q99808,Q6N075,P30825,P14174,P41440,P30536,P53985,Q9UHG3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
68,203,72,173,141,12,170,82,49,53,55,23,85,91,29
|
2272,2924,170,1801,1260,1059,1455,1956,3034,2092,1354,2182,1460,1110,12,689,2991,532,1156,2404,55,2366,324,205,85,53,23,2573,2480,2941,2237,91,1275,1525,1474,837,991,2335,68,3031,3016,671,489,2074,49,1658,2678,470,1667,173,1487,520,1840,82,72,3019,141,2389,712,2125,2634,2356,1996,2590,29,2532,1252,2502,1850,203,1449,2788,1564
|
-0.4242973311338641,-1.2346016602834036,1.2363013365837792,-0.18427244054683523,0.05351387697527753,0.14803569668995656,-0.04134201322447215,-0.25603753973957905,-2.343740308741473,-0.32800834772899334,0.006128253475181141,-0.37610541469729714,-0.04134201322447215,0.12443607605412232,5.095325835237832,0.38293496406007926,-1.6394297905679558,0.522950800501484,0.10081598985120394,-0.49676620728557386,2.5983516406440144,-0.47258553589199437,0.8471185516552913,1.1223186256989308,2.0015932231890448,2.6422040422429265,4.02275923887349,-0.618042899175275,-0.5452016332533733,-1.2847304228470318,-0.40018942775227584,1.9123959679548161,0.05351387697527753,-0.06510924961463846,-0.04134201322447215,0.28921102773708735,0.19517407509175846,-0.4484293059503235,2.2679375802329096,-2.2377862069557604,-1.975273747434785,0.40631795439279017,0.5694744024903953,-0.3039949440411763,2.773483764219382,-0.11270866851683332,-0.7155242386586748,0.5927088870625801,-0.11270866851683332,1.2363013365837792,-0.04134201322447215,0.546221743136157,-0.18427244054683523,2.0683529149150766,2.179360380668593,-2.0536619909588096,1.4405014163205085,-0.47258553589199437,0.38293496406007926,-0.32800834772899334,-0.6667314992911156,-0.4484293059503235,-0.25603753973957905,-0.618042899175275,3.702904303597902,-0.5694567741728175,0.0771753025605692,-0.5452016332533733,-0.18427244054683523,1.145146616611409,-0.017596227567052123,-0.8625447160545955,-0.06510924961463846
| 3,067
|
Secondary alcohol metabolic process
| 11
| 35
| 2.640119
| 0.008288
|
P34913,P35610,P37268,Q15392,Q16850,Q14739,Q9UBM7,Q15126,P48735,Q8WTV0,Q9UHB6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
98,102,139,77,50,182,289,246,90,27,127
|
291,857,828,931,1863,1694,1263,2508,1157,936,1316,98,102,139,1518,943,90,982,1645,2514,2999,1771,2710,2779,1122,182,246,77,1657,538,50,27,2214,289,127
|
0.9161413439901327,0.2657314452879552,0.28921102773708735,0.21871309573559264,-0.2081715578352066,-0.13654115282560736,0.05351387697527753,-0.5694567741728175,0.10081598985120394,0.21871309573559264,0.029831574171165644,1.8005977335130876,1.7333549222805171,1.4405014163205085,-0.06510924961463846,0.21871309573559264,1.9347152099627174,0.19517407509175846,-0.11270866851683332,-0.5694567741728175,-1.7678418524139115,-0.1603956915349074,-0.7644228326298534,-0.8625447160545955,0.12443607605412232,1.2135360793065495,1.030846911961832,2.0905801244850664,-0.11270866851683332,0.522950800501484,2.7297697351237553,3.8737579156642066,-0.37610541469729714,0.9391154562432038,1.5082991632477938
| 3,067
|
Protein kinase-like domain superfamily [IPR011009]
| 15
| 60
| 2.632546
| 0.008475
|
Q9HA64,Q96GD4,P07948,Q14004,O14936,P49840,Q13464,P49841,P17252,O14976,Q8NI60,P53350,P06493,P24941,P21127
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
96,65,403,38,255,11,392,46,366,363,86,88,25,26,155
|
1102,255,363,2319,2670,2277,2007,25,403,1698,366,2598,1872,2282,155,26,2756,1068,2685,1966,1877,1818,11,46,722,88,2241,1976,1222,2414,1328,839,392,1594,2934,2335,2244,38,1713,1540,426,994,1330,1931,2783,2680,86,1781,65,1939,1676,2984,1488,2172,711,2765,96,965,1998,2695
|
0.12443607605412232,0.9850140031000338,0.7548502524793712,-0.4484293059503235,-0.7155242386586748,-0.4242973311338641,-0.28000473103222856,3.95895741112925,0.6854672060130802,-0.13654115282560736,0.7548502524793712,-0.6423742870091806,-0.2081715578352066,-0.4242973311338641,1.304504542365476,3.9163763942062166,-0.83797308570648,0.14803569668995656,-0.7399601945456966,-0.25603753973957905,-0.2081715578352066,-0.18427244054683523,5.157748552028619,2.9478894554497037,0.3595328957429135,1.9570211264778132,-0.40018942775227584,-0.25603753973957905,0.0771753025605692,-0.49676620728557386,0.029831574171165644,0.28921102773708735,0.7086124029290911,-0.08889808473863031,-1.2596499307860836,-0.4484293059503235,-0.40018942775227584,3.273018749025682,-0.13654115282560736,-0.06510924961463846,0.6623043592342954,0.19517407509175846,0.029831574171165644,-0.2320932034861173,-0.8625447160545955,-0.7155242386586748,1.979313777666358,-0.1603956915349074,2.312151123677215,-0.2320932034861173,-0.11270866851683332,-1.588331377422339,-0.04134201322447215,-0.35204511338992117,0.38293496406007926,-0.83797308570648,1.8229845236200364,0.21871309573559264,-0.25603753973957905,-0.7399601945456966
| 3,067
|
Sterol metabolism
| 8
| 21
| 2.632123
| 0.008485
|
P35610,Q15392,P37268,Q16850,Q14739,Q9UBM7,Q15126,Q9UHB6
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
102,77,139,50,182,289,246,127
|
291,828,1863,1694,1263,1157,1316,102,139,1771,2710,2779,182,246,77,1657,538,50,289,127,2532
|
0.9161413439901327,0.28921102773708735,-0.2081715578352066,-0.13654115282560736,0.05351387697527753,0.10081598985120394,0.029831574171165644,1.7333549222805171,1.4405014163205085,-0.1603956915349074,-0.7644228326298534,-0.8625447160545955,1.2135360793065495,1.030846911961832,2.0905801244850664,-0.11270866851683332,0.522950800501484,2.7297697351237553,0.9391154562432038,1.5082991632477938,-0.5694567741728175
| 3,067
|
Organic acid transmembrane transport
| 10
| 31
| 2.631894
| 0.008491
|
Q9Y619,Q9BQT8,Q8TDW0,P08183,O43772,P23786,P33121,P30825,P41440,P53985
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
203,72,173,12,13,147,148,53,23,91
|
13,1455,1956,3034,2092,1460,12,689,532,147,205,53,148,23,2674,2237,91,837,3031,489,470,173,520,1840,72,2389,712,2590,1252,1850,203
|
4.970267139748916,-0.04134201322447215,-0.25603753973957905,-2.343740308741473,-0.32800834772899334,-0.04134201322447215,5.095325835237832,0.38293496406007926,0.522950800501484,1.3952290840127508,1.1223186256989308,2.6422040422429265,1.3952290840127508,4.02275923887349,-0.7155242386586748,-0.40018942775227584,1.9123959679548161,0.28921102773708735,-2.2377862069557604,0.5694744024903953,0.5927088870625801,1.2363013365837792,0.546221743136157,-0.18427244054683523,2.179360380668593,-0.47258553589199437,0.38293496406007926,-0.618042899175275,0.0771753025605692,-0.18427244054683523,1.145146616611409
| 3,067
|
Endoplasmic reticulum lumen
| 23
| 58
| 2.588919
| 0.009628
|
O75718,P07237,Q6P179,P13667,Q9Y680,Q9H173,Q14257,Q32P28,O15460,Q02818,O14975,O95881,P30101,Q13217,Q8NBS9,Q15084,Q8IXB1,O43852,Q07065,P13674,Q9NWM8,Q9BTV4,P07942
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
6,256,413,279,299,168,41,48,176,302,300,309,310,193,329,207,222,122,357,244,120,386,250
|
1104,2180,300,176,1801,122,2952,6,309,256,250,2932,279,244,1265,1213,2646,2600,2756,1514,2572,1068,642,310,1516,1879,3030,3017,302,357,193,1078,41,1425,207,411,48,1232,413,1722,492,222,957,2920,329,878,2656,1486,2660,1895,386,583,168,120,964,1140,856,299
|
0.12443607605412232,-0.37610541469729714,0.8931505508985713,1.2135360793065495,-0.18427244054683523,1.530869168826082,-1.3601684318707938,5.592772581581793,0.8701429845725451,0.9850140031000338,1.0079386178201262,-1.2596499307860836,0.9391154562432038,1.030846911961832,0.05351387697527753,0.0771753025605692,-0.691114745586028,-0.6423742870091806,-0.83797308570648,-0.06510924961463846,-0.618042899175275,0.14803569668995656,0.4296819841917649,0.8701429845725451,-0.06510924961463846,-0.2081715578352066,-2.2377862069557604,-2.0274970719938357,0.8931505508985713,0.7779431050658644,1.1679588008379829,0.14803569668995656,3.1865518455863504,-0.017596227567052123,1.1223186256989308,0.6854672060130802,2.795323733143928,0.0771753025605692,0.6854672060130802,-0.13654115282560736,0.5694744024903953,1.0994747445642425,0.21871309573559264,-1.2095852996870387,0.8471185516552913,0.2657314452879552,-0.691114745586028,-0.04134201322447215,-0.691114745586028,-0.2081715578352066,0.7317400515807754,0.4996614648715897,1.2590511132682145,1.5534246717492672,0.21871309573559264,0.12443607605412232,0.28921102773708735,0.9161413439901327
| 3,067
|
Tetrapyrrole binding
| 8
| 16
| 2.580954
| 0.009853
|
Q8WUJ1,Q6UW02,Q16850,P30519,O15173,P09601,O43169,Q9H7Z7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
3,303,50,179,277,462,460,63
|
1017,277,460,481,462,1406,179,1323,50,303,2342,3,1094,2733,63,2556
|
0.17161498562321423,0.9391154562432038,0.5927088870625801,0.5694744024903953,0.5927088870625801,-0.017596227567052123,1.2135360793065495,0.029831574171165644,2.7297697351237553,0.8931505508985713,-0.4484293059503235,7.040498432373202,0.14803569668995656,-0.7889123757164783,2.356315196972746,-0.5937371293542618
| 3,067
|
Abnormality of hepatobiliary system physiology
| 18
| 77
| 2.576955
| 0.009967
|
P00846,P03915,Q8TCJ2,Q9Y619,Q10713,P22695,O15118,P22830,O43772,O75381,O15460,P23786,P28288,Q8N511,P55263,P39210,P46100,Q16625
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
36,100,130,203,228,197,291,76,13,171,176,147,205,54,56,214,61,187
|
2224,291,176,13,1625,2135,663,171,1208,36,1865,100,1263,1572,2324,481,1962,1513,197,76,147,205,2966,941,2014,2603,3057,214,980,1580,795,2235,1070,61,2674,1921,1821,56,1922,326,1591,2909,1219,228,2414,2761,1425,1227,187,1777,394,996,808,2162,1662,54,130,1177,1431,2347,1674,919,816,1385,2261,3001,2354,2314,1141,2127,1347,658,2049,1851,2269,1198,203
|
-0.40018942775227584,0.9161413439901327,1.2135360793065495,4.970267139748916,-0.11270866851683332,-0.35204511338992117,0.40631795439279017,1.2363013365837792,0.0771753025605692,3.273018749025682,-0.2081715578352066,1.7781972459390094,0.05351387697527753,-0.08889808473863031,-0.4484293059503235,0.5694744024903953,-0.25603753973957905,-0.06510924961463846,1.145146616611409,2.1127944193228467,1.3952290840127508,1.1223186256989308,-1.4612234946070592,0.21871309573559264,-0.28000473103222856,-0.6423742870091806,-4.101822668364672,1.0994747445642425,0.19517407509175846,-0.08889808473863031,0.31267104849579785,-0.40018942775227584,0.14803569668995656,2.5105058405134244,-0.7155242386586748,-0.2320932034861173,-0.18427244054683523,2.5983516406440144,-0.2320932034861173,0.8471185516552913,-0.08889808473863031,-1.1846005429298558,0.0771753025605692,1.0766148888424223,-0.49676620728557386,-0.83797308570648,-0.017596227567052123,0.0771753025605692,1.1907552610982108,-0.1603956915349074,0.7086124029290911,0.19517407509175846,0.31267104849579785,-0.35204511338992117,-0.11270866851683332,2.6202836766402364,1.4857145839161021,0.10081598985120394,-0.017596227567052123,-0.4484293059503235,-0.11270866851683332,0.24223217662498808,0.31267104849579785,0.006128253475181141,-0.40018942775227584,-1.7678418524139115,-0.4484293059503235,-0.4242973311338641,0.12443607605412232,-0.32800834772899334,0.029831574171165644,0.4296819841917649,-0.28000473103222856,-0.18427244054683523,-0.40018942775227584,0.10081598985120394,1.145146616611409
| 3,067
|
Amyotrophic lateral sclerosis
| 7
| 15
| 2.575897
| 0.009998
|
Q96CV9,Q15165,Q92804,Q99720,P35637,P22626,P50995
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
360,40,79,17,149,463,156
|
1810,1961,482,463,794,149,1703,156,2145,1708,765,40,79,360,17
|
-0.18427244054683523,-0.25603753973957905,0.5694744024903953,0.5927088870625801,0.31267104849579785,1.3952290840127508,-0.13654115282560736,1.304504542365476,-0.35204511338992117,-0.13654115282560736,0.33611163062394667,3.229806250235141,2.0905801244850664,0.7779431050658644,4.2982861261730845
| 3,067
|
Protein hydroxylation
| 6
| 14
| 2.573133
| 0.010078
|
Q92791,O75718,P07237,Q32P28,O15460,P13674
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
5,6,256,48,176,244
|
1799,176,2952,6,256,244,697,2297,339,48,5,1486,2660,1553
|
-0.18427244054683523,1.2135360793065495,-1.3601684318707938,5.592772581581793,0.9850140031000338,1.030846911961832,0.38293496406007926,-0.4242973311338641,0.8010187077276009,2.795323733143928,5.716460207824872,-0.04134201322447215,-0.691114745586028,-0.06510924961463846
| 3,067
|
Subsets and Splits
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