term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
SLC superfamily of solute carriers
| 12
| 47
| 2.835591
| 0.004574
|
Q9H2V7,P41440,Q8TAD4,O43772,Q6NT16,P30825,Q8IXU6,Q9BQT8,P53985,Q9UBX3,Q6N075,Q70HW3
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
128,69,135,7,9,73,14,245,55,253,188,61
|
1750,761,7,2310,1670,1332,2377,2761,629,2591,1205,2416,73,69,2602,55,2113,2427,2551,264,756,188,9,1064,2696,61,14,602,135,550,1097,444,587,245,2184,335,128,1778,2470,1272,253,1174,1948,1047,2308,611,516
|
-0.2248062819916635,0.4100561090046764,4.1654432084268365,-0.540993539152877,-0.18125720694712386,0.010049356609845118,-0.5878723702209245,-0.9291418506117229,0.5426192269625886,-0.7555558469531406,0.07218715987352683,-0.6114803864575494,2.494694922423651,2.519440449494305,-0.7555558469531406,2.7009867150585474,-0.4257161927970913,-0.6114803864575494,-0.7070610806666029,1.1721916646896646,0.42921722537504836,1.458505765790809,4.156781366488055,0.19413417400581515,-0.8292038872729048,2.629209225162519,3.8242233185591332,0.5798371070730094,1.801001399719216,0.6534243244188832,0.1740206722343724,0.81500648275305,0.5983391977919877,1.2211160826760208,-0.44855622173737325,1.0054094308154349,1.8581269973639303,-0.2248062819916635,-0.6352021957308768,0.051562445642740554,1.204863382292912,0.11317649001570981,-0.31308432082275484,0.21416484143938402,-0.5177206708014539,0.5798371070730094,0.7078884093515075
| 3,069
|
Vascular process in circulatory system
| 8
| 31
| 2.795832
| 0.005177
|
P41440,P30825,Q07954,O15439,P42892,P08183,P53985,Q9HB40
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
69,73,105,137,23,53,55,26
|
1786,137,1551,877,1914,396,2620,53,2591,1672,1524,73,69,23,495,55,2113,2573,936,105,567,736,756,184,2696,2664,444,587,26,930,1948
|
-0.24672702956312,1.786611952471423,-0.11665224488806318,0.3130983356211,-0.31308432082275484,0.8851185038122356,-0.7799832529313712,2.771680946122683,-0.7555558469531406,-0.18125720694712386,-0.09530566340648955,2.494694922423651,2.519440449494305,3.5258141843000015,0.7259074169551265,2.7009867150585474,-0.4257161927970913,-0.731248835894527,0.2737663531255464,2.039170647439996,0.6167707540458557,0.44830289150821834,0.42921722537504836,1.4892849674401574,-0.8292038872729048,-0.8045322091109726,0.81500648275305,0.5983391977919877,3.4958858354923237,0.2934721608296331,-0.31308432082275484
| 3,069
|
Iron ion binding
| 6
| 20
| 2.792107
| 0.005237
|
P22830,Q15800,Q9BU89,O15460,Q6UW02,Q16850
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
12,187,87,283,126,31
|
1832,283,1551,855,504,12,2108,1056,1988,1764,187,31,326,126,2338,87,774,1316,1005,803
|
-0.2687463774668492,1.122762779001896,-0.11665224488806318,0.33264549575231883,0.7078884093515075,3.980016064166049,-0.4257161927970913,0.19413417400581515,-0.35782711761202085,-0.2248062819916635,1.458505765790809,3.3329166087539415,1.0223507884681426,1.8723015954974838,-0.540993539152877,2.2789296869171887,0.4100561090046764,0.030850084923550944,0.2341133298905719,0.39081896508326114
| 3,069
|
Side of membrane
| 22
| 69
| 2.789347
| 0.005281
|
Q14344,Q9NR28,O15439,P00813,P02786,P42892,P51790,P55899,P09471,P10321,P08183,P41440,Q9UBI6,P35579,P62942,P04439,Q12959,O96005,Q9H0H5,P10619,O00291,Q4VCS5
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
635,142,137,16,396,23,414,289,544,306,53,69,348,595,356,494,497,365,503,121,250,638
|
806,250,137,1407,365,901,16,1556,396,1520,494,1335,1252,1015,1447,53,1484,544,306,121,2063,1204,2022,1522,2103,1754,2515,902,1016,1524,880,808,2108,1130,751,666,595,2519,69,23,1759,2112,730,414,289,2824,2865,356,2785,1804,1025,1418,497,1691,1224,635,865,638,1095,1507,2664,2046,1466,503,142,348,2229,1550,898
|
0.37150520972870915,1.204863382292912,1.786611952471423,-0.031820131489916866,0.9370405358529817,0.2934721608296331,3.7205314479190315,-0.11665224488806318,0.8851185038122356,-0.09530566340648955,0.7259074169551265,0.010049356609845118,0.051562445642740554,0.21416484143938402,-0.05289037818638174,2.771680946122683,-0.07405196659429947,0.6534243244188832,1.0728192976417978,1.9145729797153146,-0.40298195769845385,0.07218715987352683,-0.3803525755016717,-0.09530566340648955,-0.4257161927970913,-0.2248062819916635,-0.6829914580738592,0.2934721608296331,0.21416484143938402,-0.09530566340648955,0.3130983356211,0.37150520972870915,-0.4257161927970913,0.13354250527191597,0.42921722537504836,0.5051128651347058,0.5798371070730094,-0.6829914580738592,2.519440449494305,3.5258141843000015,-0.2248062819916635,-0.4257161927970913,0.44830289150821834,0.8501900582323448,1.10617263797279,-1.005443892780752,-1.0829406177928378,0.9542241080917176,-0.9544453152528625,-0.24672702956312,0.21416484143938402,-0.031820131489916866,0.7259074169551265,-0.18125720694712386,0.07218715987352683,0.5426192269625886,0.33264549575231883,0.5426192269625886,0.1740206722343724,-0.07405196659429947,-0.8045322091109726,-0.3803525755016717,-0.05289037818638174,0.7259074169551265,1.786611952471423,0.9884081390522009,-0.4715029980224777,-0.09530566340648955,0.3130983356211
| 3,069
|
Intrinsic component of mitochondrial inner membrane
| 16
| 35
| 2.772408
| 0.005564
|
O43819,Q9NX63,O14925,P50336,Q9Y2R0,Q99595,Q16891,O75431,Q15070,Q9H9P8,Q9UG56,Q13505,Q5XKP0,Q9H4I9,O60830,Q5HYI7
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
627,556,563,566,66,5,526,329,399,246,574,117,570,122,27,285
|
563,627,27,329,1331,2377,2650,566,2427,117,399,1845,526,1577,285,570,789,1652,1266,1852,681,1773,1097,5,1196,122,1778,246,2470,1630,556,574,66,805,1399
|
0.6167707540458557,0.5426192269625886,3.475825517493468,1.0054094308154349,0.010049356609845118,-0.5878723702209245,-0.8045322091109726,0.6167707540458557,-0.6114803864575494,1.9564707654985696,0.8851185038122356,-0.2687463774668492,0.6898018853113626,-0.11665224488806318,1.122762779001896,0.6167707540458557,0.39081896508326114,-0.1596272157387103,0.051562445642740554,-0.2687463774668492,0.5051128651347058,-0.2248062819916635,0.1740206722343724,4.4424516811688495,0.09272494003870865,1.9145729797153146,-0.2248062819916635,1.2211160826760208,-0.6352021957308768,-0.13809249703546148,0.6534243244188832,0.6167707540458557,2.5440562997072673,0.39081896508326114,-0.010840469228635595
| 3,069
|
Peripheral demyelination
| 8
| 16
| 2.75233
| 0.005917
|
Q9NR77,P07602,P50570,P17480,P03915,P07196,P00846,O43681
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,33,320,421,229,108,15,375
|
375,15,229,108,33,421,1838,505,1920,320,598,916,2433,0,1272,2303
|
0.9197953633069056,3.7961743788849853,1.2534569702074796,1.9980012684894612,3.3121366390002813,0.8326303861028213,-0.2687463774668492,0.7078884093515075,-0.31308432082275484,1.0392326181245326,0.5798371070730094,0.2934721608296331,-0.6114803864575494,5.129020836832448,0.051562445642740554,-0.5177206708014539
| 3,069
|
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
| 7
| 14
| 2.747237
| 0.00601
|
Q13217,P07942,O43852,Q9BTY2,Q02818,Q86UP2,Q07065
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
484,354,139,112,152,473,284
|
139,1015,354,1449,1603,1640,152,284,484,2035,538,1187,473,112
|
1.786611952471423,0.21416484143938402,0.9542241080917176,-0.05289037818638174,-0.13809249703546148,-0.1596272157387103,1.6993479647673133,1.122762779001896,0.7438593924757614,-0.3803525755016717,0.6716473552783213,0.09272494003870865,0.7617448151371171,1.984198193350699
| 3,069
|
Bulbar signs
| 8
| 13
| 2.732484
| 0.006286
|
P07602,P04062,P35637,Q15043,P03915,P00846,Q99720,O43681
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
33,376,166,264,229,15,127,375
|
375,15,229,376,449,33,166,669,264,714,127,1272,2585
|
0.9197953633069056,3.7961743788849853,1.2534569702074796,0.9197953633069056,0.797317893556882,3.3121366390002813,1.5954743045989446,0.5051128651347058,1.1721916646896646,0.46731367824728265,1.8723015954974838,0.051562445642740554,-0.731248835894527
| 3,069
|
Sphingolipid metabolism
| 10
| 27
| 2.728965
| 0.006353
|
P07602,P10619,P16278,Q96G23,Q06136,P06865,Q13510,O15121,P27544,P04062
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
33,121,101,141,357,106,175,215,277,376
|
806,215,778,1079,375,1983,2017,376,483,106,33,651,121,101,902,1017,277,754,357,175,2037,2867,141,2046,2404,1272,1318
|
0.37150520972870915,1.3174905758707651,0.39081896508326114,0.1740206722343724,0.9197953633069056,-0.35782711761202085,-0.3803525755016717,0.9197953633069056,0.7438593924757614,2.0254872721470325,3.3121366390002813,0.5239023754686642,1.9145729797153146,2.0935117653992443,0.2934721608296331,0.21416484143938402,1.1392957452369128,0.42921722537504836,0.9542241080917176,1.550253920627543,-0.3803525755016717,-1.0829406177928378,1.786611952471423,-0.3803525755016717,-0.5878723702209245,0.051562445642740554,0.030850084923550944
| 3,069
|
Protein insertion into membrane
| 8
| 30
| 2.71772
| 0.006573
|
P62072,Q15629,Q96A33,Q8WWC4,P46379,Q9NS69,Q9Y584,O43681
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
71,102,401,240,17,20,153,375
|
518,1833,375,899,830,1601,1955,2276,2595,17,1210,2523,71,708,399,102,1577,2253,1849,1426,1266,240,401,1099,20,1146,1147,1399,153,1865
|
0.6898018853113626,-0.2687463774668492,0.9197953633069056,0.2934721608296331,0.35211425239127736,-0.13809249703546148,-0.3354046675661042,-0.5177206708014539,-0.7555558469531406,3.682239434852251,0.07218715987352683,-0.6829914580738592,2.5070839778403435,0.46731367824728265,0.8851185038122356,2.0935117653992443,-0.11665224488806318,-0.4945574879422671,-0.2687463774668492,-0.031820131489916866,0.051562445642740554,1.2373138262349093,0.8851185038122356,0.1740206722343724,3.6241989583234373,0.13354250527191597,0.13354250527191597,-0.010840469228635595,1.6993479647673133,-0.2687463774668492
| 3,069
|
Inorganic anion transport
| 15
| 29
| 2.702544
| 0.006881
|
Q9Y277,Q9UHG3,Q15043,O15439,P30536,Q6N075,P08183,Q9H0H5,Q9UBX3,P51790,Q8TDW0,P45880,P21796,Q9C0H2,O43681
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
429,35,264,137,144,188,53,503,253,414,415,28,29,94,375
|
2409,137,375,53,3019,29,144,28,414,3000,1608,2113,2427,2551,264,1110,188,1265,415,94,503,2637,253,35,429,1948,2308,1949,516
|
-0.6114803864575494,1.786611952471423,0.9197953633069056,2.771680946122683,-1.871225423943587,3.3741993459998163,1.7721787798962068,3.4455710952889245,0.8501900582323448,-1.6915054398535807,-0.13809249703546148,-0.4257161927970913,-0.6114803864575494,-0.7070610806666029,1.1721916646896646,0.15382367299729152,1.458505765790809,0.051562445642740554,0.8501900582323448,2.2135419004040315,0.7259074169551265,-0.7799832529313712,1.204863382292912,3.249232648120622,0.8326303861028213,-0.31308432082275484,-0.5177206708014539,-0.31308432082275484,0.7078884093515075
| 3,069
|
Outer mitochondrial membrane protein complex
| 9
| 15
| 2.701702
| 0.006899
|
Q9NX63,Q8N4H5,Q8IWA4,Q16891,O75431,Q9NS69,Q13505,Q5XKP0,Q5HYI7
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
556,130,293,526,329,20,117,570,285
|
329,1601,614,2650,117,526,285,570,1652,293,130,20,1630,556,1399
|
1.0054094308154349,-0.13809249703546148,0.5612639595076085,-0.8045322091109726,1.9564707654985696,0.6898018853113626,1.122762779001896,0.6167707540458557,-0.1596272157387103,1.10617263797279,1.829650134972895,3.6241989583234373,-0.13809249703546148,0.6534243244188832,-0.010840469228635595
| 3,069
|
Contractures of the joints of the upper limbs
| 17
| 66
| 2.687645
| 0.007196
|
Q9NR77,P16435,P37268,Q15392,P02545,P35637,P06753,P07196,Q99567,P23786,P41227,O75844,P50402,P42892,Q8IZA0,Q7LGA3,Q99720
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,470,225,58,262,166,449,108,402,236,521,295,366,23,154,157,127
|
1276,1786,1832,1401,854,2413,1551,960,1789,295,1871,262,449,108,1672,470,1128,2484,2543,236,1452,1960,2159,166,225,521,23,2822,1386,366,1799,1725,580,535,1764,997,2927,1809,2765,1692,2529,1109,3024,58,2631,157,154,1068,1189,794,1431,1821,771,2295,402,127,841,1510,2297,1944,1825,0,1376,1076,1047,1325
|
0.030850084923550944,-0.24672702956312,-0.2687463774668492,-0.031820131489916866,0.33264549575231883,-0.6114803864575494,-0.11665224488806318,0.2539802870628444,-0.24672702956312,1.089524939627866,-0.29086518455841137,1.1721916646896646,0.797317893556882,1.9980012684894612,-0.18125720694712386,0.7617448151371171,0.13354250527191597,-0.6590388605217596,-0.7070610806666029,1.2373138262349093,-0.05289037818638174,-0.3354046675661042,-0.44855622173737325,1.5954743045989446,1.2695458684021779,0.6898018853113626,3.5258141843000015,-1.005443892780752,-0.010840469228635595,0.9370405358529817,-0.24672702956312,-0.20298328683847608,0.5983391977919877,0.6716473552783213,-0.2248062819916635,0.2341133298905719,-1.2416662214532936,-0.24672702956312,-0.9291418506117229,-0.18125720694712386,-0.6829914580738592,0.15382367299729152,-1.9325942351876662,2.677182821571807,-0.7799832529313712,1.6551079756873106,1.6846469648276376,0.19413417400581515,0.09272494003870865,0.39081896508326114,-0.031820131489916866,-0.24672702956312,0.4100561090046764,-0.5177206708014539,0.8851185038122356,1.8723015954974838,0.35211425239127736,-0.07405196659429947,-0.5177206708014539,-0.31308432082275484,-0.24672702956312,5.129020836832448,0.010049356609845118,0.19413417400581515,0.21416484143938402,0.030850084923550944
| 3,069
|
Transporter activity
| 58
| 176
| 2.676513
| 0.007439
|
Q9H2V7,Q9UDW1,Q99595,O43772,Q93050,Q6NT16,Q8TAD4,Q15043,O15439,Q8WTV0,Q8IXU6,P00846,P39210,P30536,O96000,Q99567,Q9NS69,Q9Y255,Q9Y584,O60830,P45880,P21796,Q8TDW0,P51790,Q9Y277,Q9H4L5,Q9Y487,Q03519,P25705,O43674,Q96QD8,P08183,P53985,P08133,Q6N075,Q70HW3,P51991,Q96GC9,Q7Z3C6,P41440,P30825,O75964,O75027,Q9H2J7,O43676,O15173,Q13423,Q9HD20,P00403,Q9C0H2,P35670,P03915,Q6P4Q7,Q9BQT8,O15118,Q9UBX3,P04062,O43681
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
128,132,5,7,8,9,135,264,137,13,14,15,140,144,146,402,20,281,153,27,28,29,415,414,429,304,42,172,263,418,444,53,55,385,188,61,450,194,327,69,73,199,202,335,80,328,83,84,85,94,224,229,232,245,120,253,376,375
|
2706,2875,2409,1750,1751,563,761,120,328,137,418,80,2148,375,7,2310,27,202,2587,613,2617,2014,1670,2015,199,1601,1151,1332,2016,2377,146,614,85,15,229,376,1483,1336,2761,783,1203,385,53,629,1153,3019,1557,2591,1205,2416,2201,458,902,2799,1524,834,1719,2821,29,1017,785,263,1720,2712,144,73,2239,224,2320,992,1057,2278,140,69,28,1020,2989,2242,882,1879,414,3000,1987,450,1214,2602,55,2113,2359,2522,1842,2523,2427,2551,172,2930,83,676,636,1086,264,756,1968,2531,1110,1578,188,9,1064,2696,789,232,61,1264,327,1265,14,585,549,1852,602,135,550,415,13,2043,8,2130,1773,513,194,1097,444,3047,2183,402,5,1392,587,2497,245,1464,2296,2828,94,2184,335,128,304,1778,2470,84,2003,20,950,2637,1146,253,132,1274,2055,1174,1122,1782,281,429,1948,42,153,1865,455,1047,2308,1949,516,955
|
-0.8539994760110062,-1.1352868219192742,-0.6114803864575494,-0.2248062819916635,-0.2248062819916635,0.6167707540458557,0.4100561090046764,1.9145729797153146,1.0054094308154349,1.786611952471423,0.8326303861028213,2.3689750863745247,-0.44855622173737325,0.9197953633069056,4.1654432084268365,-0.540993539152877,3.475825517493468,1.3806782934951933,-0.7555558469531406,0.5612639595076085,-0.7799832529313712,-0.3803525755016717,-0.18125720694712386,-0.3803525755016717,1.3963455650807735,-0.13809249703546148,0.11317649001570981,0.010049356609845118,-0.3803525755016717,-0.5878723702209245,1.7577016250427588,0.5612639595076085,2.3048330176200653,3.7961743788849853,1.2534569702074796,0.9197953633069056,-0.07405196659429947,0.010049356609845118,-0.9291418506117229,0.39081896508326114,0.07218715987352683,0.9024881631846431,2.771680946122683,0.5426192269625886,0.11317649001570981,-1.871225423943587,-0.11665224488806318,-0.7555558469531406,0.07218715987352683,-0.6114803864575494,-0.4715029980224777,0.7795641591048054,0.2934721608296331,-0.9798788971454372,-0.09530566340648955,0.35211425239127736,-0.20298328683847608,-1.005443892780752,3.3741993459998163,0.21416484143938402,0.39081896508326114,1.1721916646896646,-0.20298328683847608,-0.8539994760110062,1.7721787798962068,2.494694922423651,-0.4945574879422671,1.2855808712415313,-0.540993539152877,0.2341133298905719,0.19413417400581515,-0.5177206708014539,1.786611952471423,2.519440449494305,3.4455710952889245,0.21416484143938402,-1.6040108138088613,-0.4945574879422671,0.3130983356211,-0.29086518455841137,0.8501900582323448,-1.6915054398535807,-0.35782711761202085,0.797317893556882,0.07218715987352683,-0.7555558469531406,2.7009867150585474,-0.4257161927970913,-0.5643770990360283,-0.6829914580738592,-0.2687463774668492,-0.6829914580738592,-0.6114803864575494,-0.7070610806666029,1.5804484768707614,-1.268621087792348,2.3562163638412286,0.5051128651347058,0.5426192269625886,0.1740206722343724,1.1721916646896646,0.42921722537504836,-0.3354046675661042,-0.6829914580738592,0.15382367299729152,-0.11665224488806318,1.458505765790809,4.156781366488055,0.19413417400581515,-0.8292038872729048,0.39081896508326114,1.2534569702074796,2.629209225162519,0.051562445642740554,1.0223507884681426,0.051562445642740554,3.8242233185591332,0.5983391977919877,0.6534243244188832,-0.2687463774668492,0.5798371070730094,1.801001399719216,0.6534243244188832,0.8501900582323448,3.961959193912149,-0.3803525755016717,4.1654432084268365,-0.4257161927970913,-0.2248062819916635,0.7078884093515075,1.4430414108153444,0.1740206722343724,0.81500648275305,-2.5214717639102737,-0.44855622173737325,0.8851185038122356,4.4424516811688495,-0.010840469228635595,0.5983391977919877,-0.6590388605217596,1.2211160826760208,-0.05289037818638174,-0.5177206708014539,-1.005443892780752,2.2135419004040315,-0.44855622173737325,1.0054094308154349,1.8581269973639303,1.089524939627866,-0.2248062819916635,-0.6352021957308768,2.330594748206502,-0.35782711761202085,3.6241989583234373,0.2737663531255464,-0.7799832529313712,0.13354250527191597,1.204863382292912,1.829650134972895,0.051562445642740554,-0.3803525755016717,0.11317649001570981,0.15382367299729152,-0.2248062819916635,1.1392957452369128,0.8326303861028213,-0.31308432082275484,2.999894420961043,1.6993479647673133,-0.2687463774668492,0.797317893556882,0.21416484143938402,-0.5177206708014539,-0.31308432082275484,0.7078884093515075,0.2737663531255464
| 3,069
|
Lipid localization
| 18
| 72
| 2.675716
| 0.007457
|
Q9H2V7,P07602,P14174,Q96GC9,O43772,Q9H4L5,Q14108,Q07954,O15439,Q8WTV0,P23786,P30536,P08183,Q9Y255,O15118,O15260,Q86Y82,Q99720
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,33,256,194,7,304,41,105,137,13,236,144,53,281,120,155,189,127
|
806,3067,761,120,155,137,7,2310,1284,1330,2314,2271,2741,2619,376,1520,1203,33,651,2590,53,2591,256,902,1017,2105,236,1720,904,144,667,655,2242,2425,1136,1684,2246,105,41,1575,1110,1578,1579,1886,2696,327,189,2366,13,2130,2436,194,2665,2183,127,2046,2296,2828,1316,128,304,1240,950,1974,1272,1318,2090,1321,2507,281,1275,2672
|
0.37150520972870915,-9.329538520107828,0.4100561090046764,1.9145729797153146,1.6551079756873106,1.786611952471423,4.1654432084268365,-0.540993539152877,0.030850084923550944,0.010049356609845118,-0.540993539152877,-0.5177206708014539,-0.9039672255899834,-0.7799832529313712,0.9197953633069056,-0.09530566340648955,0.07218715987352683,3.3121366390002813,0.5239023754686642,-0.7555558469531406,2.771680946122683,-0.7555558469531406,1.1885553643741225,0.2934721608296331,0.21416484143938402,-0.4257161927970913,1.2373138262349093,-0.20298328683847608,0.2934721608296331,1.7721787798962068,0.5051128651347058,0.5239023754686642,-0.4945574879422671,-0.6114803864575494,0.13354250527191597,-0.18125720694712386,-0.4945574879422671,2.039170647439996,3.0221139040042435,-0.11665224488806318,0.15382367299729152,-0.11665224488806318,-0.11665224488806318,-0.29086518455841137,-0.8292038872729048,1.0223507884681426,1.458505765790809,-0.5643770990360283,3.961959193912149,-0.4257161927970913,-0.6114803864575494,1.4430414108153444,-0.8045322091109726,-0.44855622173737325,1.8723015954974838,-0.3803525755016717,-0.5177206708014539,-1.005443892780752,0.030850084923550944,1.8581269973639303,1.089524939627866,0.07218715987352683,0.2737663531255464,-0.3354046675661042,0.051562445642740554,0.030850084923550944,-0.40298195769845385,0.030850084923550944,-0.6590388605217596,1.1392957452369128,0.051562445642740554,-0.8045322091109726
| 3,069
|
Organic acid transmembrane transport
| 10
| 31
| 2.66997
| 0.007586
|
P41440,O43772,P30825,Q9H2J7,P23786,P08183,Q9BQT8,P53985,Q8TDW0,Q9UBX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
69,7,73,335,236,53,245,55,415,253
|
7,1913,1670,1982,2377,1252,53,629,2591,236,1720,73,667,69,2425,2602,55,2551,888,756,1265,415,1097,444,245,335,1778,253,1174,1948,1047
|
4.1654432084268365,-0.31308432082275484,-0.18125720694712386,-0.35782711761202085,-0.5878723702209245,0.051562445642740554,2.771680946122683,0.5426192269625886,-0.7555558469531406,1.2373138262349093,-0.20298328683847608,2.494694922423651,0.5051128651347058,2.519440449494305,-0.6114803864575494,-0.7555558469531406,2.7009867150585474,-0.7070610806666029,0.3130983356211,0.42921722537504836,0.051562445642740554,0.8501900582323448,0.1740206722343724,0.81500648275305,1.2211160826760208,1.0054094308154349,-0.2248062819916635,1.204863382292912,0.11317649001570981,-0.31308432082275484,0.21416484143938402
| 3,069
|
Cholesterol binding
| 7
| 13
| 2.668698
| 0.007615
|
Q14108,Q9H4L5,P30536,O15118,P45880,P21796,O95772
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
41,304,144,120,28,29,95
|
120,705,1871,95,385,29,2105,144,655,28,41,2828,304
|
1.9145729797153146,0.46731367824728265,-0.29086518455841137,2.2003548878818564,0.9024881631846431,3.3741993459998163,-0.4257161927970913,1.7721787798962068,0.5239023754686642,3.4455710952889245,3.0221139040042435,-1.005443892780752,1.089524939627866
| 3,069
|
Sterol binding
| 7
| 16
| 2.644084
| 0.008191
|
Q14108,Q9H4L5,P30536,O15118,P45880,P21796,O95772
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
41,304,144,120,28,29,95
|
120,705,1871,95,385,29,1017,2105,144,655,28,41,2183,2296,2828,304
|
1.9145729797153146,0.46731367824728265,-0.29086518455841137,2.2003548878818564,0.9024881631846431,3.3741993459998163,0.21416484143938402,-0.4257161927970913,1.7721787798962068,0.5239023754686642,3.4455710952889245,3.0221139040042435,-0.44855622173737325,-0.5177206708014539,-1.005443892780752,1.089524939627866
| 3,069
|
Protease
| 20
| 75
| 2.623632
| 0.0087
|
Q16740,P09960,P42785,Q96RU2,P42892,Q9HB40,O43847,O75844,P28072,P55786,Q9UIQ6,O75976,Q9H3G5,Q7Z2K6,O14773,Q99436,Q5JRX3,P28074,Q96K76,P10619
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
129,386,10,280,23,26,419,295,179,54,56,196,82,343,89,115,369,244,382,121
|
1666,2410,89,419,2150,295,196,2348,2818,386,121,2729,1522,2515,179,244,2972,2274,1919,10,23,1921,1346,1293,2243,1214,496,2923,2687,54,2072,2074,3008,2902,2247,1299,129,438,369,817,818,2975,343,1001,838,1095,1461,2789,770,1892,1971,1034,382,1622,280,869,115,2581,1392,2138,82,2087,1395,1170,26,2140,1373,2403,1710,1547,1375,56,2919,805,2193
|
-0.18125720694712386,-0.6114803864575494,2.252883247492375,0.8326303861028213,-0.44855622173737325,1.089524939627866,1.4275268034370876,-0.5643770990360283,-1.005443892780752,0.9024881631846431,1.9145729797153146,-0.8789201810531422,-0.09530566340648955,-0.6829914580738592,1.5046004314061265,1.2211160826760208,-1.5180231725553075,-0.5177206708014539,-0.31308432082275484,4.130697126833025,3.5258141843000015,-0.31308432082275484,0.010049356609845118,0.030850084923550944,-0.4945574879422671,0.07218715987352683,0.7259074169551265,-1.2416662214532936,-0.8292038872729048,2.7364672632965075,-0.40298195769845385,-0.40298195769845385,-1.7506978637026818,-1.1881914882781064,-0.4945574879422671,0.030850084923550944,1.829650134972895,0.81500648275305,0.9370405358529817,0.37150520972870915,0.37150520972870915,-1.5180231725553075,0.9884081390522009,0.2341133298905719,0.35211425239127736,0.1740206722343724,-0.05289037818638174,-0.9544453152528625,0.4100561090046764,-0.29086518455841137,-0.3354046675661042,0.21416484143938402,0.9197953633069056,-0.13809249703546148,1.1392957452369128,0.33264549575231883,1.9703547683806868,-0.731248835894527,-0.010840469228635595,-0.4257161927970913,2.3689750863745247,-0.40298195769845385,-0.010840469228635595,0.11317649001570981,3.4958858354923237,-0.4257161927970913,0.010049356609845118,-0.5878723702209245,-0.18125720694712386,-0.09530566340648955,0.010049356609845118,2.7009867150585474,-1.2148568573039746,0.39081896508326114,-0.44855622173737325
| 3,069
|
Cargo receptor activity
| 6
| 8
| 2.623504
| 0.008703
|
Q5KU26,Q07954,Q14108,Q8WTV0,Q08380,O15260
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
258,105,41,13,271,155
|
155,396,105,271,41,1187,258,13
|
1.6551079756873106,0.8851185038122356,2.039170647439996,1.1557719154454555,3.0221139040042435,0.09272494003870865,1.1885553643741225,3.961959193912149
| 3,069
|
Lytic vacuole organization
| 9
| 22
| 2.621094
| 0.008765
|
Q8N511,P54802,Q9P253,O75503,Q14108,P10253,P50897,O14773,P11117
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
36,100,235,72,41,355,46,89,220
|
2674,89,72,2678,376,651,355,220,2161,46,2206,100,996,3010,41,1886,36,1743,1540,2702,1974,235
|
-0.8292038872729048,2.252883247492375,2.494694922423651,-0.8292038872729048,0.9197953633069056,0.5239023754686642,0.9542241080917176,1.3015623258049298,-0.44855622173737325,2.9325936953118417,-0.4715029980224777,2.1204499143061035,0.2341133298905719,-1.7506978637026818,3.0221139040042435,-0.29086518455841137,3.228073874739091,-0.20298328683847608,-0.09530566340648955,-0.8292038872729048,-0.3354046675661042,1.2534569702074796
| 3,069
|
Metalloprotease
| 8
| 26
| 2.619278
| 0.008812
|
Q7Z2K6,P09960,O75976,O75844,Q5JRX3,P55786,P42892,Q9UIQ6
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
343,386,196,295,369,54,23,56
|
2410,419,2150,295,196,386,2729,1522,23,2243,54,369,818,343,1461,1622,869,1392,2138,2087,2140,1373,1710,1547,56,805
|
-0.6114803864575494,0.8326303861028213,-0.44855622173737325,1.089524939627866,1.4275268034370876,0.9024881631846431,-0.8789201810531422,-0.09530566340648955,3.5258141843000015,-0.4945574879422671,2.7364672632965075,0.9370405358529817,0.37150520972870915,0.9884081390522009,-0.05289037818638174,-0.13809249703546148,0.33264549575231883,-0.010840469228635595,-0.4257161927970913,-0.40298195769845385,-0.4257161927970913,0.010049356609845118,-0.18125720694712386,-0.09530566340648955,2.7009867150585474,0.39081896508326114
| 3,069
|
Calcium ion import
| 7
| 12
| 2.604094
| 0.009212
|
O14936,Q8IYU8,Q8WWC4,O75844,Q9H4I9,P21796,Q9BPX6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
395,273,240,295,122,29,159
|
395,295,458,29,1131,273,1852,240,681,159,122,805
|
0.8851185038122356,1.089524939627866,0.7795641591048054,3.3741993459998163,0.13354250527191597,1.1557719154454555,-0.2687463774668492,1.2373138262349093,0.5051128651347058,1.625384500578365,1.9145729797153146,0.39081896508326114
| 3,069
|
Mental deterioration
| 23
| 89
| 2.600617
| 0.009306
|
P21964,P00846,P21912,P27544,P07602,P35637,Q14108,Q9Y487,P50897,Q13510,O75503,P00403,Q03164,P22626,P35670,P54802,P16278,Q96F07,P06865,P03915,O15118,P04062,O43681
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
11,15,397,277,33,166,41,42,46,175,72,85,340,349,224,100,101,361,106,229,120,376,375
|
1326,543,120,375,627,830,900,1180,2708,613,72,1408,1752,2017,614,85,15,229,376,2921,106,33,651,2316,2833,832,2542,1485,101,421,902,1128,505,397,11,349,2709,277,2024,1084,166,224,992,2278,1920,2598,669,1986,46,2852,1799,100,1725,2071,1218,2328,340,1571,1930,1025,3043,1418,536,1422,175,41,814,2250,815,570,1030,1814,2767,1617,1889,2433,361,1540,2581,2983,1143,1707,949,2829,1272,572,2007,826,42
|
0.010049356609845118,0.6534243244188832,1.9145729797153146,0.9197953633069056,0.5426192269625886,0.35211425239127736,0.2934721608296331,0.09272494003870865,-0.8539994760110062,0.5612639595076085,2.494694922423651,-0.031820131489916866,-0.2248062819916635,-0.3803525755016717,0.5612639595076085,2.3048330176200653,3.7961743788849853,1.2534569702074796,0.9197953633069056,-1.2416662214532936,2.0254872721470325,3.3121366390002813,0.5239023754686642,-0.540993539152877,-1.0311416178800303,0.35211425239127736,-0.7070610806666029,-0.07405196659429947,2.0935117653992443,0.8326303861028213,0.2934721608296331,0.13354250527191597,0.7078884093515075,0.8851185038122356,4.060404520025005,0.9713465029462117,-0.8539994760110062,1.1392957452369128,-0.3803525755016717,0.1740206722343724,1.5954743045989446,1.2855808712415313,0.2341133298905719,-0.5177206708014539,-0.31308432082275484,-0.7555558469531406,0.5051128651347058,-0.35782711761202085,2.9325936953118417,-1.056973407774157,-0.24672702956312,2.1204499143061035,-0.20298328683847608,-0.40298195769845385,0.07218715987352683,-0.540993539152877,0.9884081390522009,-0.11665224488806318,-0.31308432082275484,0.21416484143938402,-2.452540335611361,-0.031820131489916866,0.6716473552783213,-0.031820131489916866,1.550253920627543,3.0221139040042435,0.37150520972870915,-0.4945574879422671,0.37150520972870915,0.6167707540458557,0.21416484143938402,-0.24672702956312,-0.9291418506117229,-0.13809249703546148,-0.29086518455841137,-0.6114803864575494,0.9542241080917176,-0.09530566340648955,-0.731248835894527,-1.5465213678572585,0.13354250527191597,-0.18125720694712386,0.2737663531255464,-1.005443892780752,0.051562445642740554,0.6167707540458557,-0.35782711761202085,0.37150520972870915,2.999894420961043
| 3,069
|
Abnormal cardiac ventricular function
| 7
| 16
| 2.596436
| 0.00942
|
P02545,P03915,P10253,O75844,P00403,P46100,Q15233
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
262,229,355,295,85,151,350
|
295,85,262,229,1337,355,1205,397,2024,2454,151,1413,2330,350,1621,2342
|
1.089524939627866,2.3048330176200653,1.1721916646896646,1.2534569702074796,0.010049356609845118,0.9542241080917176,0.07218715987352683,0.8851185038122356,-0.3803525755016717,-0.6352021957308768,1.6993479647673133,-0.031820131489916866,-0.540993539152877,0.9713465029462117,-0.13809249703546148,-0.540993539152877
| 3,069
|
Circulatory system process
| 12
| 76
| 2.587646
| 0.009663
|
P41440,P30825,P42785,P09601,O15439,Q07954,P00813,P08183,P53985,P42892,Q9UIQ6,Q9HB40
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
69,73,10,43,137,105,16,53,55,23,56,26
|
1326,1786,137,1551,877,990,295,2846,1914,1752,1555,16,396,2620,1335,1483,1336,53,43,3055,355,2591,1672,2776,2103,3013,458,991,2648,1524,2484,2711,751,963,73,69,1796,2161,10,23,495,1563,1799,55,2113,1133,1134,1570,2573,936,105,497,567,707,635,736,756,184,818,2696,2942,1000,2749,2664,1368,444,587,478,26,1171,1547,3014,930,56,1948,898
|
0.010049356609845118,-0.24672702956312,1.786611952471423,-0.11665224488806318,0.3130983356211,0.2341133298905719,1.089524939627866,-1.056973407774157,-0.31308432082275484,-0.2248062819916635,-0.11665224488806318,3.7205314479190315,0.8851185038122356,-0.7799832529313712,0.010049356609845118,-0.07405196659429947,0.010049356609845118,2.771680946122683,2.966365414770548,-3.227748904184478,0.9542241080917176,-0.7555558469531406,-0.18125720694712386,-0.9544453152528625,-0.4257161927970913,-1.7805588252111975,0.7795641591048054,0.2341133298905719,-0.8045322091109726,-0.09530566340648955,-0.6590388605217596,-0.8539994760110062,0.42921722537504836,0.2539802870628444,2.494694922423651,2.519440449494305,-0.24672702956312,-0.44855622173737325,4.130697126833025,3.5258141843000015,0.7259074169551265,-0.11665224488806318,-0.24672702956312,2.7009867150585474,-0.4257161927970913,0.13354250527191597,0.13354250527191597,-0.11665224488806318,-0.731248835894527,0.2737663531255464,2.039170647439996,0.7259074169551265,0.6167707540458557,0.46731367824728265,0.5426192269625886,0.44830289150821834,0.42921722537504836,1.4892849674401574,0.37150520972870915,-0.8292038872729048,-1.3229734732184608,0.2341133298905719,-0.9039672255899834,-0.8045322091109726,0.010049356609845118,0.81500648275305,0.5983391977919877,0.7617448151371171,3.4958858354923237,0.11317649001570981,-0.09530566340648955,-1.7805588252111975,0.2934721608296331,2.7009867150585474,-0.31308432082275484,0.3130983356211
| 3,069
|
Abnormal peripheral myelination
| 11
| 30
| 2.575237
| 0.010017
|
Q9NR77,P07602,P50570,P02545,P17480,P03915,P07196,P39210,P00846,Q9H4A3,O43681
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,33,320,262,421,229,108,140,15,478,375
|
778,375,2413,1408,2511,15,262,229,108,33,421,1838,505,2709,140,1920,320,2206,598,1419,735,2575,916,714,2433,478,0,1272,2303,1325
|
0.39081896508326114,0.9197953633069056,-0.6114803864575494,-0.031820131489916866,-0.6829914580738592,3.7961743788849853,1.1721916646896646,1.2534569702074796,1.9980012684894612,3.3121366390002813,0.8326303861028213,-0.2687463774668492,0.7078884093515075,-0.8539994760110062,1.786611952471423,-0.31308432082275484,1.0392326181245326,-0.4715029980224777,0.5798371070730094,-0.031820131489916866,0.44830289150821834,-0.731248835894527,0.2934721608296331,0.46731367824728265,-0.6114803864575494,0.7617448151371171,5.129020836832448,0.051562445642740554,-0.5177206708014539,0.030850084923550944
| 3,069
|
Abnormal csf protein level
| 6
| 11
| 2.57359
| 0.010065
|
Q9NR77,P07602,P03915,P00403,Q16625,O43681
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,33,229,85,184,375
|
2267,375,85,229,33,505,1291,2113,184,0,1272
|
-0.5177206708014539,0.9197953633069056,2.3048330176200653,1.2534569702074796,3.3121366390002813,0.7078884093515075,0.030850084923550944,-0.4257161927970913,1.4892849674401574,5.129020836832448,0.051562445642740554
| 3,069
|
Intrinsic component of plasma membrane
| 36
| 87
| 2.565741
| 0.010296
|
Q8TAD4,Q15043,Q9NR28,Q8WTV0,P11717,P02786,O00264,P98172,Q8TDW0,P51790,O00592,Q9UNN8,Q99805,Q92796,P36551,P10321,Q96QD8,P53985,Q9UIQ6,O43813,P41440,P30825,Q9H2J7,P16615,O15121,O43657,Q86UP2,Q14BN4,Q13641,O15031,P20645,P35670,Q07954,P04439,O96005,O15118
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
135,264,142,13,269,396,517,535,415,414,543,160,427,301,558,306,444,55,56,311,69,73,335,458,215,90,473,342,471,219,96,224,105,494,365,120
|
806,517,1750,543,219,120,215,2268,90,311,856,365,1556,396,494,1483,1336,2761,1252,1447,3055,306,726,2591,1204,269,1205,458,1640,1524,96,1342,1130,73,2277,706,224,558,69,730,414,55,2720,2113,535,2427,2551,105,675,1421,1526,658,471,1691,342,264,865,911,756,473,1265,1502,1656,1939,135,415,13,1114,301,444,1392,427,587,699,3068,1589,2184,335,142,1779,56,1174,1104,160,1948,954,2308
|
0.37150520972870915,0.6898018853113626,-0.2248062819916635,0.6534243244188832,1.3015623258049298,1.9145729797153146,1.3174905758707651,-0.5177206708014539,2.252883247492375,1.0560553218353965,0.33264549575231883,0.9370405358529817,-0.11665224488806318,0.8851185038122356,0.7259074169551265,-0.07405196659429947,0.010049356609845118,-0.9291418506117229,0.051562445642740554,-0.05289037818638174,-3.227748904184478,1.0728192976417978,0.44830289150821834,-0.7555558469531406,0.07218715987352683,1.1557719154454555,0.07218715987352683,0.7795641591048054,-0.1596272157387103,-0.09530566340648955,2.1871309307140887,0.010049356609845118,0.13354250527191597,2.494694922423651,-0.5177206708014539,0.46731367824728265,1.2855808712415313,0.6351322925467491,2.519440449494305,0.44830289150821834,0.8501900582323448,2.7009867150585474,-0.8539994760110062,-0.4257161927970913,0.6716473552783213,-0.6114803864575494,-0.7070610806666029,2.039170647439996,0.5051128651347058,-0.031820131489916866,-0.09530566340648955,0.5239023754686642,0.7617448151371171,-0.18125720694712386,0.9884081390522009,1.1721916646896646,0.33264549575231883,0.2934721608296331,0.42921722537504836,0.7617448151371171,0.051562445642740554,-0.07405196659429947,-0.1596272157387103,-0.31308432082275484,1.801001399719216,0.8501900582323448,3.961959193912149,0.15382367299729152,1.089524939627866,0.81500648275305,-0.010840469228635595,0.8326303861028213,0.5983391977919877,0.4862501500603866,-9.991266101484795,-0.11665224488806318,-0.44855622173737325,1.0054094308154349,1.786611952471423,-0.2248062819916635,2.7009867150585474,0.11317649001570981,0.1740206722343724,1.625384500578365,-0.31308432082275484,0.2737663531255464,-0.5177206708014539
| 3,069
|
Transition metal ion transport
| 7
| 13
| 2.551108
| 0.010738
|
P35670,P50570,Q8TAD4,Q15043,O75027,O15173,Q9HD20
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
224,320,135,264,202,328,84
|
328,202,396,224,320,2328,1763,812,264,602,135,1778,84
|
1.0054094308154349,1.3806782934951933,0.8851185038122356,1.2855808712415313,1.0392326181245326,-0.540993539152877,-0.2248062819916635,0.37150520972870915,1.1721916646896646,0.5798371070730094,1.801001399719216,-0.2248062819916635,2.330594748206502
| 3,069
|
Inner mitochondrial membrane organization
| 8
| 22
| 2.530844
| 0.011379
|
Q9NX63,P62072,Q16891,O75431,Q8WWC4,Q13505,Q9Y584,Q5HYI7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
556,71,526,329,240,117,153,285
|
830,900,329,1601,1332,2650,71,117,526,1577,285,570,1652,240,1196,1630,556,1146,805,1399,153,1865
|
0.35211425239127736,0.2934721608296331,1.0054094308154349,-0.13809249703546148,0.010049356609845118,-0.8045322091109726,2.5070839778403435,1.9564707654985696,0.6898018853113626,-0.11665224488806318,1.122762779001896,0.6167707540458557,-0.1596272157387103,1.2373138262349093,0.09272494003870865,-0.13809249703546148,0.6534243244188832,0.13354250527191597,0.39081896508326114,-0.010840469228635595,1.6993479647673133,-0.2687463774668492
| 3,069
|
Clumsiness
| 8
| 20
| 2.517265
| 0.011827
|
Q9NR77,P07602,P35670,O75503,Q15067,Q13510,O14773,O43681
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,33,224,72,299,175,89,375
|
612,3011,89,1401,375,627,72,449,33,2024,1084,224,2598,175,299,2124,1814,0,1272,2007
|
0.5612639595076085,-1.7805588252111975,2.252883247492375,-0.031820131489916866,0.9197953633069056,0.5426192269625886,2.494694922423651,0.797317893556882,3.3121366390002813,-0.3803525755016717,0.1740206722343724,1.2855808712415313,-0.7555558469531406,1.550253920627543,1.089524939627866,-0.4257161927970913,-0.24672702956312,5.129020836832448,0.051562445642740554,-0.35782711761202085
| 3,069
|
Ceramide metabolic process
| 8
| 19
| 2.516847
| 0.011841
|
Q99805,Q96G23,P06865,Q8NCC3,Q13510,O15121,P27544,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
427,141,106,109,175,215,277,376
|
215,778,1079,2017,376,483,106,651,902,277,1383,1684,175,2037,1577,109,141,427,2404
|
1.3174905758707651,0.39081896508326114,0.1740206722343724,-0.3803525755016717,0.9197953633069056,0.7438593924757614,2.0254872721470325,0.5239023754686642,0.2934721608296331,1.1392957452369128,-0.010840469228635595,-0.18125720694712386,1.550253920627543,-0.3803525755016717,-0.11665224488806318,1.9980012684894612,1.786611952471423,0.8326303861028213,-0.5878723702209245
| 3,069
|
Peripheral axonal neuropathy
| 12
| 53
| 2.515414
| 0.011889
|
P50570,P07602,O95831,Q8IV08,P03915,P07196,P39210,Q15067,P00846,P00403,P22626,Q9BPX6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
320,33,64,39,229,108,140,299,15,85,349,159
|
2376,778,1079,2413,900,1477,1408,64,85,15,229,1053,108,2818,33,2316,832,1205,1838,349,2421,786,140,2203,1347,1986,320,1725,2071,2030,1764,1419,997,2997,2250,299,2252,2123,2362,1814,1530,39,1427,416,2135,159,2137,2470,1512,951,1272,805,1325
|
-0.5878723702209245,0.39081896508326114,0.1740206722343724,-0.6114803864575494,0.2934721608296331,-0.07405196659429947,-0.031820131489916866,2.5440562997072673,2.3048330176200653,3.7961743788849853,1.2534569702074796,0.19413417400581515,1.9980012684894612,-1.005443892780752,3.3121366390002813,-0.540993539152877,0.35211425239127736,0.07218715987352683,-0.2687463774668492,0.9713465029462117,-0.6114803864575494,0.39081896508326114,1.786611952471423,-0.4715029980224777,0.010049356609845118,-0.35782711761202085,1.0392326181245326,-0.20298328683847608,-0.40298195769845385,-0.3803525755016717,-0.2248062819916635,-0.031820131489916866,0.2341133298905719,-1.6621699792153193,-0.4945574879422671,1.089524939627866,-0.4945574879422671,-0.4257161927970913,-0.5643770990360283,-0.24672702956312,-0.09530566340648955,3.033184055432667,-0.031820131489916866,0.8501900582323448,-0.4257161927970913,1.625384500578365,-0.4257161927970913,-0.6352021957308768,-0.07405196659429947,0.2737663531255464,0.051562445642740554,0.39081896508326114,0.030850084923550944
| 3,069
|
Activation of nmda receptors and postsynaptic events
| 12
| 24
| 2.514384
| 0.011924
|
Q13885,Q9BVA1,Q92796,O14936,P07196,P52292,P51812,Q12959,Q15418,Q14168,P68371,Q14012
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
525,303,301,395,108,461,81,497,52,436,312,537
|
395,108,1485,545,991,2648,2710,1960,859,81,461,884,2785,312,497,997,1885,525,537,436,865,52,301,303
|
0.8851185038122356,1.9980012684894612,-0.07405196659429947,0.6534243244188832,0.2341133298905719,-0.8045322091109726,-0.8539994760110062,-0.3354046675661042,0.33264549575231883,2.3689750863745247,0.7795641591048054,0.3130983356211,-0.9544453152528625,1.0560553218353965,0.7259074169551265,0.2341133298905719,-0.29086518455841137,0.6898018853113626,0.6716473552783213,0.81500648275305,0.33264549575231883,2.7950103777212996,1.089524939627866,1.089524939627866
| 3,069
|
Organic acid transmembrane transporter activity
| 8
| 22
| 2.511894
| 0.012009
|
P41440,P30825,Q9H2J7,O15439,P08183,Q9BQT8,P53985,Q9UBX3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
69,73,335,137,53,245,55,253
|
761,137,1670,2377,53,629,73,69,2602,55,2551,756,2696,1097,444,245,335,1778,253,1174,1948,1047
|
0.4100561090046764,1.786611952471423,-0.18125720694712386,-0.5878723702209245,2.771680946122683,0.5426192269625886,2.494694922423651,2.519440449494305,-0.7555558469531406,2.7009867150585474,-0.7070610806666029,0.42921722537504836,-0.8292038872729048,0.1740206722343724,0.81500648275305,1.2211160826760208,1.0054094308154349,-0.2248062819916635,1.204863382292912,0.11317649001570981,-0.31308432082275484,0.21416484143938402
| 3,069
|
Protein targeting to mitochondrion
| 8
| 48
| 2.509188
| 0.012101
|
Q8N4H5,O95831,Q99595,P62072,P30536,Q9NS69,P55786,O60830
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,64,5,71,144,20,54,27
|
612,1277,518,563,1283,830,27,2150,1601,1408,2728,2151,64,614,1955,2775,2451,144,2595,835,1563,730,54,71,2163,536,2660,472,1577,369,2840,130,548,916,1369,5,1392,2668,2583,20,1146,1375,2813,647,2094,1399,153,1865
|
0.5612639595076085,0.030850084923550944,0.6898018853113626,0.6167707540458557,0.030850084923550944,0.35211425239127736,3.475825517493468,-0.44855622173737325,-0.13809249703546148,-0.031820131489916866,-0.8789201810531422,-0.44855622173737325,2.5440562997072673,0.5612639595076085,-0.3354046675661042,-0.9544453152528625,-0.6352021957308768,1.7721787798962068,-0.7555558469531406,0.35211425239127736,-0.11665224488806318,0.44830289150821834,2.7364672632965075,2.5070839778403435,-0.44855622173737325,0.6716473552783213,-0.8045322091109726,0.7617448151371171,-0.11665224488806318,0.9370405358529817,-1.0311416178800303,1.829650134972895,0.6534243244188832,0.2934721608296331,0.010049356609845118,4.4424516811688495,-0.010840469228635595,-0.8045322091109726,-0.731248835894527,3.6241989583234373,0.13354250527191597,0.010049356609845118,-0.9798788971454372,0.5426192269625886,-0.40298195769845385,-0.010840469228635595,1.6993479647673133,-0.2687463774668492
| 3,069
|
Membrane microdomain
| 8
| 64
| 2.500656
| 0.012396
|
P41440,P09601,Q8WTV0,P50897,Q86Y82,O15118,O14773,P21796
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
69,43,13,46,189,120,89,29
|
2477,543,89,120,1407,1871,2679,1335,1483,1336,2761,1252,2906,1203,410,1447,1484,43,1485,2591,1409,545,1754,991,2648,2515,1640,1838,1524,880,29,263,1342,2710,1960,1156,1206,1131,706,1677,69,671,2112,2384,46,2212,1728,535,1685,497,1765,658,1224,1160,1886,189,2464,13,2581,699,1171,1321,1397,1782
|
-0.6590388605217596,0.6534243244188832,2.252883247492375,1.9145729797153146,-0.031820131489916866,-0.29086518455841137,-0.8292038872729048,0.010049356609845118,-0.07405196659429947,0.010049356609845118,-0.9291418506117229,0.051562445642740554,-1.2148568573039746,0.07218715987352683,0.8501900582323448,-0.05289037818638174,-0.07405196659429947,2.966365414770548,-0.07405196659429947,-0.7555558469531406,-0.031820131489916866,0.6534243244188832,-0.2248062819916635,0.2341133298905719,-0.8045322091109726,-0.6829914580738592,-0.1596272157387103,-0.2687463774668492,-0.09530566340648955,0.3130983356211,3.3741993459998163,1.1721916646896646,0.010049356609845118,-0.8539994760110062,-0.3354046675661042,0.11317649001570981,0.07218715987352683,0.13354250527191597,0.46731367824728265,-0.18125720694712386,2.519440449494305,0.5051128651347058,-0.4257161927970913,-0.5878723702209245,2.9325936953118417,-0.4715029980224777,-0.20298328683847608,0.6716473552783213,-0.18125720694712386,0.7259074169551265,-0.2248062819916635,0.5239023754686642,0.07218715987352683,0.11317649001570981,-0.29086518455841137,1.458505765790809,-0.6352021957308768,3.961959193912149,-0.731248835894527,0.4862501500603866,0.11317649001570981,0.030850084923550944,-0.010840469228635595,-0.2248062819916635
| 3,069
|
Cilium assembly
| 20
| 59
| 2.498687
| 0.012465
|
Q7Z4L5,Q9H6D7,Q13885,A0AVF1,Q7Z4H7,O60645,O43924,A6NIH7,P07437,Q9BVA1,P78371,P41208,Q92973,O95684,P68371,O94927,O75935,Q9UPT5,O43805,Q13561
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
259,131,525,384,265,519,21,22,410,303,298,297,443,57,312,431,62,206,91,508
|
384,22,91,21,519,1404,62,431,57,615,410,1955,991,2648,2156,2516,1383,1722,297,2907,1347,1798,2070,2601,1565,2387,1217,1218,1134,1728,312,298,536,2826,997,508,525,2213,814,2997,938,864,1226,1653,265,259,3036,2177,1033,443,622,918,2182,1236,303,1393,131,206,2147
|
0.9024881631846431,3.5752683604226285,2.2398058840394475,3.585096022897552,0.6898018853113626,-0.031820131489916866,2.5929041667562163,0.81500648275305,2.677182821571807,0.5612639595076085,0.8501900582323448,-0.3354046675661042,0.2341133298905719,-0.8045322091109726,-0.44855622173737325,-0.6829914580738592,-0.010840469228635595,-0.20298328683847608,1.089524939627866,-1.2148568573039746,0.010049356609845118,-0.24672702956312,-0.40298195769845385,-0.7555558469531406,-0.11665224488806318,-0.5878723702209245,0.07218715987352683,0.07218715987352683,0.13354250527191597,-0.20298328683847608,1.0560553218353965,1.089524939627866,0.6716473552783213,-1.005443892780752,0.2341133298905719,0.7078884093515075,0.6898018853113626,-0.4715029980224777,0.37150520972870915,-1.6621699792153193,0.2737663531255464,0.33264549575231883,0.07218715987352683,-0.1596272157387103,1.1721916646896646,1.1885553643741225,-2.185857809271104,-0.44855622173737325,0.21416484143938402,0.81500648275305,0.5612639595076085,0.2934721608296331,-0.44855622173737325,0.07218715987352683,1.089524939627866,-0.010840469228635595,1.829650134972895,1.3806782934951933,-0.4257161927970913
| 3,069
|
Protein transmembrane transport
| 6
| 25
| 2.49419
| 0.012624
|
O95831,Q99595,Q15629,Q9NS69,Q9Y584,O60830
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,5,102,20,153,27
|
563,1283,27,2642,170,1601,64,614,2775,1672,882,2653,2211,2523,2930,102,472,548,1141,5,2583,20,1274,153,3021
|
0.6167707540458557,0.030850084923550944,3.475825517493468,-0.8045322091109726,1.5804484768707614,-0.13809249703546148,2.5440562997072673,0.5612639595076085,-0.9544453152528625,-0.18125720694712386,0.3130983356211,-0.8045322091109726,-0.4715029980224777,-0.6829914580738592,-1.268621087792348,2.0935117653992443,0.7617448151371171,0.6534243244188832,0.13354250527191597,4.4424516811688495,-0.731248835894527,3.6241989583234373,0.051562445642740554,1.6993479647673133,-1.871225423943587
| 3,069
|
Abnormality of hepatobiliary system physiology
| 20
| 77
| 2.492706
| 0.012677
|
O43772,P22830,P39210,Q96A33,P00846,P55263,P46100,O15460,Q8N511,O75381,Q13510,P22695,Q6NUQ1,Q16625,P56589,P35670,P03915,P23786,O15118,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
7,12,140,401,15,149,151,283,36,170,175,296,180,184,331,224,229,236,120,376
|
1475,120,283,7,627,2149,613,170,1182,15,1556,229,376,2153,1835,1153,1337,2820,296,12,236,1720,654,224,1962,2596,1018,140,2067,423,1985,2835,1920,151,2425,935,2571,149,2030,331,1928,908,2327,536,2764,175,1844,2331,184,2036,737,570,180,2533,1111,36,475,2395,401,2435,1036,1462,740,1143,2500,3049,2005,1899,685,930,2342,1147,1749,2095,2614,3021,1047
|
-0.07405196659429947,1.9145729797153146,1.122762779001896,4.1654432084268365,0.5426192269625886,-0.44855622173737325,0.5612639595076085,1.5804484768707614,0.09272494003870865,3.7961743788849853,-0.11665224488806318,1.2534569702074796,0.9197953633069056,-0.44855622173737325,-0.2687463774668492,0.11317649001570981,0.010049356609845118,-1.005443892780752,1.089524939627866,3.980016064166049,1.2373138262349093,-0.20298328683847608,0.5239023754686642,1.2855808712415313,-0.3354046675661042,-0.7555558469531406,0.21416484143938402,1.786611952471423,-0.40298195769845385,0.8326303861028213,-0.35782711761202085,-1.0311416178800303,-0.31308432082275484,1.6993479647673133,-0.6114803864575494,0.2737663531255464,-0.731248835894527,1.7140036634995972,-0.3803525755016717,1.0054094308154349,-0.31308432082275484,0.2934721608296331,-0.540993539152877,0.6716473552783213,-0.9291418506117229,1.550253920627543,-0.2687463774668492,-0.540993539152877,1.4892849674401574,-0.3803525755016717,0.44830289150821834,0.6167707540458557,1.5046004314061265,-0.6829914580738592,0.15382367299729152,3.228073874739091,0.7617448151371171,-0.5878723702209245,0.8851185038122356,-0.6114803864575494,0.21416484143938402,-0.05289037818638174,0.44830289150821834,0.13354250527191597,-0.6590388605217596,-2.5913555631402323,-0.35782711761202085,-0.29086518455841137,0.5051128651347058,0.2934721608296331,-0.540993539152877,0.13354250527191597,-0.20298328683847608,-0.40298195769845385,-0.7555558469531406,-1.871225423943587,0.21416484143938402
| 3,069
|
Active transmembrane transporter activity
| 22
| 74
| 2.490642
| 0.012751
|
Q9UDW1,Q15043,O15439,O96000,P51790,Q03519,O43674,Q96QD8,P08183,P53985,Q9Y5K8,P41440,O75027,Q9H2J7,O43676,P16615,Q9HD20,P00403,P35670,P03915,Q96ES6,Q9UBX3
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
132,264,137,146,414,172,418,444,53,55,455,69,202,335,80,458,84,85,224,229,513,253
|
2875,1750,1751,137,418,80,2148,202,2587,613,2617,2014,1151,1332,2016,146,85,229,1483,1336,2761,783,53,629,1153,1557,1205,2416,2201,458,2799,1524,834,1719,2821,1720,2712,2239,224,992,2278,69,1020,1879,414,3000,1987,2602,55,2113,1842,2427,2551,172,264,756,1968,2531,1264,1852,513,444,335,84,2003,1146,253,132,2055,1948,455,2308,516,955
|
-1.1352868219192742,-0.2248062819916635,-0.2248062819916635,1.786611952471423,0.8326303861028213,2.3689750863745247,-0.44855622173737325,1.3806782934951933,-0.7555558469531406,0.5612639595076085,-0.7799832529313712,-0.3803525755016717,0.11317649001570981,0.010049356609845118,-0.3803525755016717,1.7577016250427588,2.3048330176200653,1.2534569702074796,-0.07405196659429947,0.010049356609845118,-0.9291418506117229,0.39081896508326114,2.771680946122683,0.5426192269625886,0.11317649001570981,-0.11665224488806318,0.07218715987352683,-0.6114803864575494,-0.4715029980224777,0.7795641591048054,-0.9798788971454372,-0.09530566340648955,0.35211425239127736,-0.20298328683847608,-1.005443892780752,-0.20298328683847608,-0.8539994760110062,-0.4945574879422671,1.2855808712415313,0.2341133298905719,-0.5177206708014539,2.519440449494305,0.21416484143938402,-0.29086518455841137,0.8501900582323448,-1.6915054398535807,-0.35782711761202085,-0.7555558469531406,2.7009867150585474,-0.4257161927970913,-0.2687463774668492,-0.6114803864575494,-0.7070610806666029,1.5804484768707614,1.1721916646896646,0.42921722537504836,-0.3354046675661042,-0.6829914580738592,0.051562445642740554,-0.2687463774668492,0.7078884093515075,0.81500648275305,1.0054094308154349,2.330594748206502,-0.35782711761202085,0.13354250527191597,1.204863382292912,1.829650134972895,-0.3803525755016717,-0.31308432082275484,0.797317893556882,-0.5177206708014539,0.7078884093515075,0.2737663531255464
| 3,069
|
Proximal muscle weakness
| 24
| 65
| 2.48364
| 0.013005
|
P51114,Q8TD16,P02545,Q9BUK6,P00846,P21912,Q8NFF5,Q9BPX6,P35637,Q13510,P36551,Q9Y5P6,Q8NI60,P50570,Q13126,P06753,Q8NAT1,P22626,P35670,P10253,P07196,P50402,Q9BQT8,Q99720
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
506,391,262,531,15,397,540,159,166,175,558,576,181,320,67,449,474,349,224,355,108,366,245,127
|
900,2952,1408,1983,15,262,2482,449,108,2316,832,355,2820,1205,1409,991,2648,1838,397,2543,349,2024,166,224,558,566,366,320,506,1292,2602,2071,2981,2656,67,1422,175,658,735,2765,1224,2997,2330,736,659,816,1530,1093,866,474,540,181,916,391,1189,714,921,127,159,245,841,531,1947,576,1325
|
0.2934721608296331,-1.3779265486799217,-0.031820131489916866,-0.35782711761202085,3.7961743788849853,1.1721916646896646,-0.6590388605217596,0.797317893556882,1.9980012684894612,-0.540993539152877,0.35211425239127736,0.9542241080917176,-1.005443892780752,0.07218715987352683,-0.031820131489916866,0.2341133298905719,-0.8045322091109726,-0.2687463774668492,0.8851185038122356,-0.7070610806666029,0.9713465029462117,-0.3803525755016717,1.5954743045989446,1.2855808712415313,0.6351322925467491,0.6167707540458557,0.9370405358529817,1.0392326181245326,0.7078884093515075,0.030850084923550944,-0.7555558469531406,-0.40298195769845385,-1.5465213678572585,-0.8045322091109726,2.5317645022419932,-0.031820131489916866,1.550253920627543,0.5239023754686642,0.44830289150821834,-0.9291418506117229,0.07218715987352683,-1.6621699792153193,-0.540993539152877,0.44830289150821834,0.5239023754686642,0.37150520972870915,-0.09530566340648955,0.1740206722343724,0.33264549575231883,0.7617448151371171,0.6716473552783213,1.5046004314061265,0.2934721608296331,0.9024881631846431,0.09272494003870865,0.46731367824728265,0.2934721608296331,1.8723015954974838,1.625384500578365,1.2211160826760208,0.35211425239127736,0.6898018853113626,-0.31308432082275484,0.6167707540458557,0.030850084923550944
| 3,069
|
Translocase
| 7
| 23
| 2.478672
| 0.013187
|
P35670,Q03519,O15439,Q13423,Q9HD20,P08183,P00403
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
224,172,137,83,84,53,85
|
2875,137,2587,613,2014,85,229,1483,783,53,1153,458,2799,1524,2712,224,2278,1020,1879,172,83,585,84
|
-1.1352868219192742,1.786611952471423,-0.7555558469531406,0.5612639595076085,-0.3803525755016717,2.3048330176200653,1.2534569702074796,-0.07405196659429947,0.39081896508326114,2.771680946122683,0.11317649001570981,0.7795641591048054,-0.9798788971454372,-0.09530566340648955,-0.8539994760110062,1.2855808712415313,-0.5177206708014539,0.21416484143938402,-0.29086518455841137,1.5804484768707614,2.3562163638412286,0.5983391977919877,2.330594748206502
| 3,069
|
protein modifying enzyme
| 6
| 21
| 2.472775
| 0.013407
|
Q92791,P50897,Q9UMR5,P51812,Q15418,O15460
|
Functions
|
Panther Protein class
|
panther_protein_class
|
200,46,110,81,52,283
|
1832,1667,2567,283,1551,1126,324,650,504,46,81,1764,1883,2896,52,1616,1459,200,1626,110,2446
|
-0.2687463774668492,-0.18125720694712386,-0.731248835894527,1.122762779001896,-0.11665224488806318,0.13354250527191597,1.0223507884681426,0.5239023754686642,0.7078884093515075,2.9325936953118417,2.3689750863745247,-0.2248062819916635,-0.29086518455841137,-1.1616686303195873,2.7950103777212996,-0.13809249703546148,-0.05289037818638174,1.3963455650807735,-0.13809249703546148,1.9980012684894612,-0.6114803864575494
| 3,069
|
Alcohol binding
| 7
| 16
| 2.469991
| 0.013512
|
Q9H4L5,Q14108,P30536,O15118,P45880,P21796,O95772
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
304,41,144,120,28,29,95
|
2844,120,2449,705,1871,95,385,29,2105,904,144,655,28,41,2828,304
|
-1.056973407774157,1.9145729797153146,-0.6352021957308768,0.46731367824728265,-0.29086518455841137,2.2003548878818564,0.9024881631846431,3.3741993459998163,-0.4257161927970913,0.2934721608296331,1.7721787798962068,0.5239023754686642,3.4455710952889245,3.0221139040042435,-1.005443892780752,1.089524939627866
| 3,069
|
Mitochondrial calcium ion transport
| 6
| 17
| 2.459505
| 0.013913
|
Q8IYU8,Q8WWC4,Q9H4I9,P45880,P21796,Q9BPX6
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
273,240,122,28,29,159
|
2150,1332,29,2277,28,536,273,1852,240,769,869,2372,159,122,1321,429,805
|
-0.44855622173737325,0.010049356609845118,3.3741993459998163,-0.5177206708014539,3.4455710952889245,0.6716473552783213,1.1557719154454555,-0.2687463774668492,1.2373138262349093,0.4100561090046764,0.33264549575231883,-0.5643770990360283,1.625384500578365,1.9145729797153146,0.030850084923550944,0.8326303861028213,0.39081896508326114
| 3,069
|
Juvenile onset
| 14
| 39
| 2.456946
| 0.014012
|
Q9NR77,P50570,P54802,P41440,P02545,P16278,O75027,P07196,P39210,Q14566,Q13510,Q03252,O15118,O14773
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,320,100,69,262,101,202,108,140,237,175,314,120,89
|
89,120,202,2742,262,2921,483,449,108,101,2421,595,1722,1018,140,2203,69,1347,2383,862,366,320,1257,3000,100,580,314,2656,1158,175,1932,237,637,1068,2184,2263,0,2887,2614
|
2.252883247492375,1.9145729797153146,1.3806782934951933,-0.9039672255899834,1.1721916646896646,-1.2416662214532936,0.7438593924757614,0.797317893556882,1.9980012684894612,2.0935117653992443,-0.6114803864575494,0.5798371070730094,-0.20298328683847608,0.21416484143938402,1.786611952471423,-0.4715029980224777,2.519440449494305,0.010049356609845118,-0.5878723702209245,0.33264549575231883,0.9370405358529817,1.0392326181245326,0.051562445642740554,-1.6915054398535807,2.1204499143061035,0.5983391977919877,1.0560553218353965,-0.8045322091109726,0.11317649001570981,1.550253920627543,-0.31308432082275484,1.2373138262349093,0.5426192269625886,0.19413417400581515,-0.44855622173737325,-0.4945574879422671,5.129020836832448,-1.1352868219192742,-0.7555558469531406
| 3,069
|
Secretory granule membrane
| 14
| 72
| 2.44529
| 0.014474
|
P07602,Q96JJ7,Q8TAD4,Q93050,Q9NQX7,P42785,O15439,P11717,P30519,P10321,O15121,O15260,Q07065,P20073
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
33,234,135,8,103,10,137,269,19,306,215,155,284,319
|
2265,517,761,215,1125,155,137,2100,519,831,2708,2832,628,1556,33,355,306,1204,269,1409,3013,319,1342,19,963,1961,706,2067,10,1759,882,1642,2206,1645,2733,809,2721,996,2212,2785,1728,2912,284,675,1419,1686,1159,2574,2078,1160,1110,2558,890,1886,512,1939,135,1114,8,1820,234,2497,1542,2184,1072,103,950,1272,1318,2843,455,1595
|
-0.5177206708014539,0.6898018853113626,0.4100561090046764,1.3174905758707651,0.13354250527191597,1.6551079756873106,1.786611952471423,-0.4257161927970913,0.6898018853113626,0.35211425239127736,-0.8539994760110062,-1.0311416178800303,0.5426192269625886,-0.11665224488806318,3.3121366390002813,0.9542241080917176,1.0728192976417978,0.07218715987352683,1.1557719154454555,-0.031820131489916866,-1.7805588252111975,1.0392326181245326,0.010049356609845118,3.6629735845084817,0.2539802870628444,-0.3354046675661042,0.46731367824728265,-0.40298195769845385,4.130697126833025,-0.2248062819916635,0.3130983356211,-0.1596272157387103,-0.4715029980224777,-0.1596272157387103,-0.8789201810531422,0.37150520972870915,-0.8539994760110062,0.2341133298905719,-0.4715029980224777,-0.9544453152528625,-0.20298328683847608,-1.2148568573039746,1.122762779001896,0.5051128651347058,-0.031820131489916866,-0.18125720694712386,0.11317649001570981,-0.731248835894527,-0.40298195769845385,0.11317649001570981,0.15382367299729152,-0.7070610806666029,0.3130983356211,-0.29086518455841137,0.7078884093515075,-0.31308432082275484,1.801001399719216,0.15382367299729152,4.1654432084268365,-0.24672702956312,1.2534569702074796,-0.6590388605217596,-0.09530566340648955,-0.44855622173737325,0.19413417400581515,2.0935117653992443,0.2737663531255464,0.051562445642740554,0.030850084923550944,-1.0311416178800303,0.797317893556882,-0.11665224488806318
| 3,069
|
Abnormal muscle fiber morphology
| 17
| 67
| 2.443737
| 0.014536
|
P50570,O95831,P35637,P02545,P61978,P03915,P07196,P23786,P00846,O14979,O43676,Q8NI60,P00403,P22626,Q70HW3,Q99720,Q9BPX6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
320,64,166,262,231,229,108,236,15,176,80,181,85,349,61,127,159
|
1751,176,80,2413,900,2952,64,614,85,15,262,229,2945,449,108,2019,832,1205,565,2543,349,236,2024,1084,166,2424,669,366,320,506,2602,1022,2071,231,1764,2656,658,2765,1224,2997,2330,2605,2288,1089,61,1530,1093,866,1427,181,2395,1189,2752,127,159,2943,841,531,741,1708,1896,2374,1147,1947,805,2614,576
|
-0.2248062819916635,1.535084607730633,2.3689750863745247,-0.6114803864575494,0.2934721608296331,-1.3779265486799217,2.5440562997072673,0.5612639595076085,2.3048330176200653,3.7961743788849853,1.1721916646896646,1.2534569702074796,-1.3503741258266342,0.797317893556882,1.9980012684894612,-0.3803525755016717,0.35211425239127736,0.07218715987352683,0.6167707540458557,-0.7070610806666029,0.9713465029462117,1.2373138262349093,-0.3803525755016717,0.1740206722343724,1.5954743045989446,-0.6114803864575494,0.5051128651347058,0.9370405358529817,1.0392326181245326,0.7078884093515075,-0.7555558469531406,0.21416484143938402,-0.40298195769845385,1.2534569702074796,-0.2248062819916635,-0.8045322091109726,0.5239023754686642,-0.9291418506117229,0.07218715987352683,-1.6621699792153193,-0.540993539152877,-0.7555558469531406,-0.5177206708014539,0.1740206722343724,2.629209225162519,-0.09530566340648955,0.1740206722343724,0.33264549575231883,-0.031820131489916866,1.5046004314061265,-0.5878723702209245,0.09272494003870865,-0.9039672255899834,1.8723015954974838,1.625384500578365,-1.3229734732184608,0.35211425239127736,0.6898018853113626,0.44830289150821834,-0.18125720694712386,-0.29086518455841137,-0.5643770990360283,0.13354250527191597,-0.31308432082275484,0.39081896508326114,-0.7555558469531406,0.6167707540458557
| 3,069
|
Assembly and cell surface presentation of nmda receptors
| 7
| 11
| 2.421749
| 0.015446
|
Q9BVA1,Q92796,O14936,P07196,Q12959,Q14168,P68371
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
303,301,395,108,497,436,312
|
395,108,312,497,997,1885,525,436,865,301,303
|
0.8851185038122356,1.9980012684894612,1.0560553218353965,0.7259074169551265,0.2341133298905719,-0.29086518455841137,0.6898018853113626,0.81500648275305,0.33264549575231883,1.089524939627866,1.089524939627866
| 3,069
|
Exopeptidase activity
| 14
| 32
| 2.416282
| 0.01568
|
Q7Z2K6,P09960,O75976,O14773,P42785,P53582,O75844,Q9H3G5,P02786,P55786,Q8IYS1,Q9UIQ6,P10619,Q9HB40
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
343,386,196,89,10,496,295,82,396,54,539,56,121,26
|
89,295,196,396,386,121,2729,2972,2274,558,10,496,2923,54,2763,2902,818,343,1001,539,1891,1115,1622,2497,82,2087,26,2140,1373,1710,1547,56
|
2.252883247492375,1.089524939627866,1.4275268034370876,0.8851185038122356,0.9024881631846431,1.9145729797153146,-0.8789201810531422,-1.5180231725553075,-0.5177206708014539,0.6351322925467491,4.130697126833025,0.7259074169551265,-1.2416662214532936,2.7364672632965075,-0.9291418506117229,-1.1881914882781064,0.37150520972870915,0.9884081390522009,0.2341133298905719,0.6716473552783213,-0.29086518455841137,0.15382367299729152,-0.13809249703546148,-0.6590388605217596,2.3689750863745247,-0.40298195769845385,3.4958858354923237,-0.4257161927970913,0.010049356609845118,-0.18125720694712386,-0.09530566340648955,2.7009867150585474
| 3,069
|
Organophosphate ester transport
| 8
| 29
| 2.40944
| 0.015977
|
Q96GC9,Q7Z3C6,P41440,Q14108,O15439,Q8WTV0,P08183,Q9Y255
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
194,327,69,41,137,13,53,281
|
1750,137,2310,2761,53,1205,2416,1017,2105,69,2242,1684,675,41,1110,1578,1064,327,1265,550,415,13,194,587,2828,2470,950,1318,281
|
-0.2248062819916635,1.786611952471423,-0.540993539152877,-0.9291418506117229,2.771680946122683,0.07218715987352683,-0.6114803864575494,0.21416484143938402,-0.4257161927970913,2.519440449494305,-0.4945574879422671,-0.18125720694712386,0.5051128651347058,3.0221139040042435,0.15382367299729152,-0.11665224488806318,0.19413417400581515,1.0223507884681426,0.051562445642740554,0.6534243244188832,0.8501900582323448,3.961959193912149,1.4430414108153444,0.5983391977919877,-1.005443892780752,-0.6352021957308768,0.2737663531255464,0.030850084923550944,1.1392957452369128
| 3,069
|
Respiratory failure
| 26
| 62
| 2.402974
| 0.016262
|
O43819,Q8TD16,Q16637,Q96CV9,P07602,P35637,P33991,P43243,Q13510,Q9Y5P6,Q15165,Q5XKP0,P50995,Q70HW3,Q92734,P06753,Q8NBU5,Q8N183,Q9BT22,Q96EY7,P53701,Q92804,P10253,P23786,O75306,P43897
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
627,391,659,407,33,166,38,669,175,576,51,570,434,61,714,449,585,738,740,604,97,99,355,236,613,753
|
627,1180,613,1872,1983,449,33,2512,832,355,2103,3013,1129,2484,2157,236,38,166,1985,1920,669,753,1606,434,1022,97,2071,2571,1422,175,1224,814,51,659,2081,2123,1231,570,61,2663,738,1427,585,2366,391,714,99,1621,407,604,2943,740,2137,1143,1510,1239,1896,2005,1272,803,576,1047
|
0.5426192269625886,0.09272494003870865,0.5612639595076085,-0.29086518455841137,-0.35782711761202085,0.797317893556882,3.3121366390002813,-0.6829914580738592,0.35211425239127736,0.9542241080917176,-0.4257161927970913,-1.7805588252111975,0.13354250527191597,-0.6590388605217596,-0.44855622173737325,1.2373138262349093,3.1532502936771563,1.5954743045989446,-0.35782711761202085,-0.31308432082275484,0.5051128651347058,0.42921722537504836,-0.13809249703546148,0.81500648275305,0.21416484143938402,2.147235382078263,-0.40298195769845385,-0.731248835894527,-0.031820131489916866,1.550253920627543,0.07218715987352683,0.37150520972870915,2.8066316074577466,0.5239023754686642,-0.40298195769845385,-0.4257161927970913,0.07218715987352683,0.6167707540458557,2.629209225162519,-0.8045322091109726,0.44830289150821834,-0.031820131489916866,0.5983391977919877,-0.5643770990360283,0.9024881631846431,0.46731367824728265,2.1338616289497745,-0.13809249703546148,0.8676859490502526,0.5798371070730094,-1.3229734732184608,0.44830289150821834,-0.4257161927970913,0.13354250527191597,-0.07405196659429947,0.07218715987352683,-0.29086518455841137,-0.35782711761202085,0.051562445642740554,0.39081896508326114,0.6167707540458557,0.21416484143938402
| 3,069
|
Postural tremor
| 8
| 18
| 2.388617
| 0.016912
|
Q9NR77,P35637,Q14108,P03915,Q9H6K4,P00846,O14773,O75569
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,166,41,229,336,15,89,430
|
89,1401,613,430,1408,1983,15,229,505,166,1725,3043,41,2581,336,1708,0,826
|
2.252883247492375,-0.031820131489916866,0.5612639595076085,0.81500648275305,-0.031820131489916866,-0.35782711761202085,3.7961743788849853,1.2534569702074796,0.7078884093515075,1.5954743045989446,-0.20298328683847608,-2.452540335611361,3.0221139040042435,-0.731248835894527,1.0054094308154349,-0.18125720694712386,5.129020836832448,0.37150520972870915
| 3,069
|
Response to oxygen levels
| 7
| 59
| 2.386945
| 0.016989
|
Q8N511,Q9Y487,P09601,P00846,P00813,P30519,P55786
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
36,42,43,15,16,19,54
|
1247,1832,2845,404,877,613,2348,2480,64,2679,16,15,262,396,229,2620,1334,1336,3001,1015,43,2591,1603,2515,1559,2452,19,2202,1919,2278,2161,2240,2112,1799,906,54,1842,1764,2901,2492,2914,547,2766,1000,36,1700,1537,971,465,2436,2398,2372,587,1709,1372,826,42,1634,2192
|
0.051562445642740554,-0.2687463774668492,-1.056973407774157,0.8676859490502526,0.3130983356211,0.5612639595076085,-0.5643770990360283,-0.6590388605217596,2.5440562997072673,-0.8292038872729048,3.7205314479190315,3.7961743788849853,1.1721916646896646,0.8851185038122356,1.2534569702074796,-0.7799832529313712,0.010049356609845118,0.010049356609845118,-1.7210140739331303,0.21416484143938402,2.966365414770548,-0.7555558469531406,-0.13809249703546148,-0.6829914580738592,-0.11665224488806318,-0.6352021957308768,3.6629735845084817,-0.4715029980224777,-0.31308432082275484,-0.5177206708014539,-0.44855622173737325,-0.4945574879422671,-0.4257161927970913,-0.24672702956312,0.2934721608296331,2.7364672632965075,-0.2687463774668492,-0.2248062819916635,-1.1881914882781064,-0.6590388605217596,-1.2148568573039746,0.6534243244188832,-0.9291418506117229,0.2341133298905719,3.228073874739091,-0.18125720694712386,-0.09530566340648955,0.2539802870628444,0.7795641591048054,-0.6114803864575494,-0.5878723702209245,-0.5643770990360283,0.5983391977919877,-0.18125720694712386,0.010049356609845118,0.37150520972870915,2.999894420961043,-0.13809249703546148,-0.44855622173737325
| 3,069
|
Toe walking
| 8
| 21
| 2.385453
| 0.017058
|
P07602,O95831,Q8TD16,P35637,P02545,P50402,Q99720,O43681
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
33,64,391,166,262,366,127,375
|
375,64,262,449,33,166,1985,366,2602,1725,2071,2571,598,2765,1740,391,1189,127,841,1272,1325
|
0.9197953633069056,2.5440562997072673,1.1721916646896646,0.797317893556882,3.3121366390002813,1.5954743045989446,-0.35782711761202085,0.9370405358529817,-0.7555558469531406,-0.20298328683847608,-0.40298195769845385,-0.731248835894527,0.5798371070730094,-0.9291418506117229,-0.20298328683847608,0.9024881631846431,0.09272494003870865,1.8723015954974838,0.35211425239127736,0.051562445642740554,0.030850084923550944
| 3,069
|
Glycosaminoglycan metabolism
| 7
| 12
| 2.3833
| 0.017158
|
P54802,P16278,Q8TB61,P06865,O43505,P15586,Q7LGA3
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
100,101,550,106,493,652,157
|
1281,493,1480,106,651,1055,652,101,100,157,550,2344
|
0.030850084923550944,0.7259074169551265,-0.07405196659429947,2.0254872721470325,0.5239023754686642,0.19413417400581515,0.5239023754686642,2.0935117653992443,2.1204499143061035,1.6551079756873106,0.6534243244188832,-0.540993539152877
| 3,069
|
Dementia
| 15
| 50
| 2.379314
| 0.017345
|
P35670,P07602,P35637,Q14108,Q9Y487,P06865,P03915,P00846,Q13510,P00403,O15118,P27544,P22626,P04062,O43681
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
224,33,166,41,42,106,229,15,175,85,120,277,349,376,375
|
1326,543,120,375,830,900,2708,614,85,15,229,376,2921,106,33,832,2542,902,505,397,349,2709,277,2024,1084,166,224,992,2278,2598,669,1799,1725,2071,1571,3043,1422,175,41,814,815,2767,1617,1889,2433,1540,2581,1272,572,42
|
0.010049356609845118,0.6534243244188832,1.9145729797153146,0.9197953633069056,0.35211425239127736,0.2934721608296331,-0.8539994760110062,0.5612639595076085,2.3048330176200653,3.7961743788849853,1.2534569702074796,0.9197953633069056,-1.2416662214532936,2.0254872721470325,3.3121366390002813,0.35211425239127736,-0.7070610806666029,0.2934721608296331,0.7078884093515075,0.8851185038122356,0.9713465029462117,-0.8539994760110062,1.1392957452369128,-0.3803525755016717,0.1740206722343724,1.5954743045989446,1.2855808712415313,0.2341133298905719,-0.5177206708014539,-0.7555558469531406,0.5051128651347058,-0.24672702956312,-0.20298328683847608,-0.40298195769845385,-0.11665224488806318,-2.452540335611361,-0.031820131489916866,1.550253920627543,3.0221139040042435,0.37150520972870915,0.37150520972870915,-0.9291418506117229,-0.13809249703546148,-0.29086518455841137,-0.6114803864575494,-0.09530566340648955,-0.731248835894527,0.051562445642740554,0.6167707540458557,2.999894420961043
| 3,069
|
Action tremor
| 13
| 52
| 2.377242
| 0.017443
|
Q9NR77,P07602,Q99720,P41440,P35637,Q14108,Q9H6K4,O75027,P03915,P00846,Q5JRX3,O14773,Q15233
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,33,127,69,166,41,336,202,229,15,369,89,350
|
2411,89,1401,2773,375,202,613,430,1408,1983,15,229,2921,33,2590,1128,1559,2319,505,2105,2623,1876,2160,166,69,1839,1212,2357,1725,598,3043,41,350,369,816,2124,1030,790,1502,1657,2581,127,1510,336,1708,2140,0,2637,1272,572,826,805
|
-0.6114803864575494,2.252883247492375,-0.031820131489916866,-0.9544453152528625,0.9197953633069056,1.3806782934951933,0.5612639595076085,0.81500648275305,-0.031820131489916866,-0.35782711761202085,3.7961743788849853,1.2534569702074796,-1.2416662214532936,3.3121366390002813,-0.7555558469531406,0.13354250527191597,-0.11665224488806318,-0.540993539152877,0.7078884093515075,-0.4257161927970913,-0.7799832529313712,-0.29086518455841137,-0.44855622173737325,1.5954743045989446,2.519440449494305,-0.2687463774668492,0.07218715987352683,-0.5643770990360283,-0.20298328683847608,0.5798371070730094,-2.452540335611361,3.0221139040042435,0.9713465029462117,0.9370405358529817,0.37150520972870915,-0.4257161927970913,0.21416484143938402,0.39081896508326114,-0.07405196659429947,-0.1596272157387103,-0.731248835894527,1.8723015954974838,-0.07405196659429947,1.0054094308154349,-0.18125720694712386,-0.4257161927970913,5.129020836832448,-0.7799832529313712,0.051562445642740554,0.6167707540458557,0.37150520972870915,0.39081896508326114
| 3,069
|
Abnormality of the phalanges of the toes
| 7
| 14
| 2.366048
| 0.017979
|
P02545,O14936,O75431,O75844,Q9H4A3,P98172,Q7LGA3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
262,395,329,295,478,535,157
|
395,329,295,262,544,1719,535,1419,2631,157,1037,1168,478,1631
|
0.8851185038122356,1.0054094308154349,1.089524939627866,1.1721916646896646,0.6534243244188832,-0.20298328683847608,0.6716473552783213,-0.031820131489916866,-0.7799832529313712,1.6551079756873106,0.21416484143938402,0.11317649001570981,0.7617448151371171,-0.13809249703546148
| 3,069
|
Anion transmembrane transport
| 12
| 44
| 2.365397
| 0.018011
|
Q9UHG3,P41440,P30825,O15439,P45880,P08183,Q9BQT8,P53985,Q9UBX3,Q8TDW0,P51790,P21796
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
35,69,73,137,28,53,245,55,253,415,414,29
|
137,2310,1913,1670,1982,2377,2761,1252,53,629,1205,2416,29,73,69,28,414,3000,2602,55,2113,2427,2551,1765,636,888,756,1110,1265,550,415,1097,245,1778,2470,1895,253,35,1174,429,1948,1047,2308,516
|
1.786611952471423,-0.540993539152877,-0.31308432082275484,-0.18125720694712386,-0.35782711761202085,-0.5878723702209245,-0.9291418506117229,0.051562445642740554,2.771680946122683,0.5426192269625886,0.07218715987352683,-0.6114803864575494,3.3741993459998163,2.494694922423651,2.519440449494305,3.4455710952889245,0.8501900582323448,-1.6915054398535807,-0.7555558469531406,2.7009867150585474,-0.4257161927970913,-0.6114803864575494,-0.7070610806666029,-0.2248062819916635,0.5426192269625886,0.3130983356211,0.42921722537504836,0.15382367299729152,0.051562445642740554,0.6534243244188832,0.8501900582323448,0.1740206722343724,1.2211160826760208,-0.2248062819916635,-0.6352021957308768,-0.29086518455841137,1.204863382292912,3.249232648120622,0.11317649001570981,0.8326303861028213,-0.31308432082275484,0.21416484143938402,-0.5177206708014539,0.7078884093515075
| 3,069
|
Organelle envelope lumen
| 17
| 39
| 2.349597
| 0.018794
|
Q9BPX6,O14925,O95831,P50336,O00584,P62072,Q8N4Q1,Q9Y3B8,Q9NR28,Q16891,P36404,Q8IYU8,P11717,P36551,Q9Y255,Q96BR5,P07437
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
159,563,64,566,162,71,548,201,142,526,460,273,269,558,281,416,410
|
612,162,563,830,900,64,410,1447,269,2515,2712,460,558,566,1987,2243,2207,71,1495,526,1577,1091,1817,273,548,2395,771,416,2581,159,870,2138,1239,2051,142,1321,281,201,1865
|
0.5612639595076085,1.6104528839435324,0.6167707540458557,0.35211425239127736,0.2934721608296331,2.5440562997072673,0.8501900582323448,-0.05289037818638174,1.1557719154454555,-0.6829914580738592,-0.8539994760110062,0.7795641591048054,0.6351322925467491,0.6167707540458557,-0.35782711761202085,-0.4945574879422671,-0.4715029980224777,2.5070839778403435,-0.07405196659429947,0.6898018853113626,-0.11665224488806318,0.1740206722343724,-0.24672702956312,1.1557719154454555,0.6534243244188832,-0.5878723702209245,0.4100561090046764,0.8501900582323448,-0.731248835894527,1.625384500578365,0.33264549575231883,-0.4257161927970913,0.07218715987352683,-0.3803525755016717,1.786611952471423,0.030850084923550944,1.1392957452369128,1.3963455650807735,-0.2687463774668492
| 3,069
|
Amyotrophic lateral sclerosis
| 6
| 15
| 2.342438
| 0.019158
|
Q92804,P35637,Q15165,Q96CV9,P22626,Q99720
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
99,166,51,407,349,127
|
1983,2512,832,349,1084,166,669,434,2071,1422,814,51,99,407,127
|
-0.35782711761202085,-0.6829914580738592,0.35211425239127736,0.9713465029462117,0.1740206722343724,1.5954743045989446,0.5051128651347058,0.81500648275305,-0.40298195769845385,-0.031820131489916866,0.37150520972870915,2.8066316074577466,2.1338616289497745,0.8676859490502526,1.8723015954974838
| 3,069
|
Abnormal oral physiology
| 15
| 52
| 2.324272
| 0.020111
|
Q9NR77,Q96CV9,P35670,Q92804,P55795,P35637,Q9BVA1,Q92796,P51812,Q15165,P46100,P50995,O15460,Q03252,Q15233
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,407,224,99,197,166,303,301,81,51,151,434,283,314,350
|
1401,283,2099,1983,1556,2153,449,2512,1484,2833,832,2542,1485,652,2422,786,166,224,2203,2625,669,151,1212,434,1799,1841,81,2113,2071,197,598,1682,314,1422,997,814,2214,600,1811,51,350,621,301,99,2789,407,2295,303,2297,1824,0,1901
|
-0.031820131489916866,1.122762779001896,-0.4257161927970913,-0.35782711761202085,-0.11665224488806318,-0.44855622173737325,0.797317893556882,-0.6829914580738592,-0.07405196659429947,-1.0311416178800303,0.35211425239127736,-0.7070610806666029,-0.07405196659429947,0.5239023754686642,-0.6114803864575494,0.39081896508326114,1.5954743045989446,1.2855808712415313,-0.4715029980224777,-0.7799832529313712,0.5051128651347058,1.6993479647673133,0.07218715987352683,0.81500648275305,-0.24672702956312,-0.2687463774668492,2.3689750863745247,-0.4257161927970913,-0.40298195769845385,1.4275268034370876,0.5798371070730094,-0.18125720694712386,1.0560553218353965,-0.031820131489916866,0.2341133298905719,0.37150520972870915,-0.4715029980224777,0.5798371070730094,-0.24672702956312,2.8066316074577466,0.9713465029462117,0.5612639595076085,1.089524939627866,2.1338616289497745,-0.9544453152528625,0.8676859490502526,-0.5177206708014539,1.089524939627866,-0.5177206708014539,-0.24672702956312,5.129020836832448,-0.29086518455841137
| 3,069
|
Intermediate filament protein, conserved site [IPR018039]
| 7
| 8
| 2.307913
| 0.021004
|
P20700,P02545,P07196,P08670,Q16352,Q03252,P07197
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
505,262,108,79,111,314,216
|
262,108,216,79,505,631,314,111
|
1.1721916646896646,1.9980012684894612,1.3174905758707651,2.381699326728409,0.7078884093515075,0.5426192269625886,1.0560553218353965,1.984198193350699
| 3,069
|
Intermediate filament, rod domain [IPR039008]
| 7
| 8
| 2.307913
| 0.021004
|
P20700,P02545,P07196,P08670,Q16352,Q03252,P07197
|
Sequence
|
InterPro Domain
|
interpro_domain
|
505,262,108,79,111,314,216
|
262,108,216,79,505,631,314,111
|
1.1721916646896646,1.9980012684894612,1.3174905758707651,2.381699326728409,0.7078884093515075,0.5426192269625886,1.0560553218353965,1.984198193350699
| 3,069
|
Myoclonus
| 20
| 90
| 2.305417
| 0.021143
|
P00846,P27544,P07602,Q14108,P50897,Q13510,Q96CU9,Q8NI60,Q03252,O75503,Q13813,Q01105,P00403,O14773,Q969G3,Q96F07,P03915,Q00577,Q9UBX3,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
15,277,33,41,46,175,49,181,314,72,332,208,85,89,359,361,229,368,253,376
|
1751,2411,543,89,395,2196,72,2313,1752,748,614,457,85,15,229,376,2921,33,2833,544,2591,2201,2319,1719,1450,277,751,2202,2024,1675,1962,1290,2278,2598,1986,1879,1212,46,1799,883,1022,1646,1218,673,368,2328,208,314,1930,1025,1418,536,1419,863,175,332,41,2997,1692,2605,2362,1030,790,2083,1164,585,181,359,2130,49,2608,604,361,2134,1539,2790,1037,1369,1143,1707,1239,1708,949,1898,1272,253,1711,954,805,2815
|
-0.2248062819916635,-0.6114803864575494,0.6534243244188832,2.252883247492375,0.8851185038122356,-0.4715029980224777,2.494694922423651,-0.540993539152877,-0.2248062819916635,0.42921722537504836,0.5612639595076085,0.7795641591048054,2.3048330176200653,3.7961743788849853,1.2534569702074796,0.9197953633069056,-1.2416662214532936,3.3121366390002813,-1.0311416178800303,0.6534243244188832,-0.7555558469531406,-0.4715029980224777,-0.540993539152877,-0.20298328683847608,-0.05289037818638174,1.1392957452369128,0.42921722537504836,-0.4715029980224777,-0.3803525755016717,-0.18125720694712386,-0.3354046675661042,0.030850084923550944,-0.5177206708014539,-0.7555558469531406,-0.35782711761202085,-0.29086518455841137,0.07218715987352683,2.9325936953118417,-0.24672702956312,0.3130983356211,0.21416484143938402,-0.1596272157387103,0.07218715987352683,0.5051128651347058,0.9370405358529817,-0.540993539152877,1.3649594882179477,1.0560553218353965,-0.31308432082275484,0.21416484143938402,-0.031820131489916866,0.6716473552783213,-0.031820131489916866,0.33264549575231883,1.550253920627543,1.0054094308154349,3.0221139040042435,-1.6621699792153193,-0.18125720694712386,-0.7555558469531406,-0.5643770990360283,0.21416484143938402,0.39081896508326114,-0.40298195769845385,0.11317649001570981,0.5983391977919877,1.5046004314061265,0.9542241080917176,-0.4257161927970913,2.898575851463229,-0.7555558469531406,0.5798371070730094,0.9542241080917176,-0.4257161927970913,-0.09530566340648955,-0.9544453152528625,0.21416484143938402,0.010049356609845118,0.13354250527191597,-0.18125720694712386,0.07218715987352683,-0.18125720694712386,0.2737663531255464,-0.29086518455841137,0.051562445642740554,1.204863382292912,-0.18125720694712386,0.2737663531255464,0.39081896508326114,-0.9798788971454372
| 3,069
|
Mitochondrial calcium ion homeostasis
| 8
| 11
| 2.304889
| 0.021173
|
P51572,P08133,Q16891,Q8IYU8,Q8WWC4,Q9H4I9,Q96AQ8,Q9BPX6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
730,385,526,273,240,122,681,159
|
1332,385,730,526,273,1852,240,681,159,122,805
|
0.010049356609845118,0.9024881631846431,0.44830289150821834,0.6898018853113626,1.1557719154454555,-0.2687463774668492,1.2373138262349093,0.5051128651347058,1.625384500578365,1.9145729797153146,0.39081896508326114
| 3,069
|
Abnormality of salivation
| 13
| 40
| 2.303586
| 0.021246
|
Q9NR77,Q96CV9,P35670,Q92804,P55795,P35637,Q9BVA1,Q92796,P51812,Q15165,P46100,Q03252,Q15233
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,407,224,99,197,166,303,301,81,51,151,314,350
|
1401,2099,1983,1556,2512,2833,832,2542,652,2422,786,166,224,2625,669,151,1212,434,1799,1841,81,2113,2071,197,598,314,1422,814,600,51,350,301,99,2789,407,2295,303,2297,0,1901
|
-0.031820131489916866,-0.4257161927970913,-0.35782711761202085,-0.11665224488806318,-0.6829914580738592,-1.0311416178800303,0.35211425239127736,-0.7070610806666029,0.5239023754686642,-0.6114803864575494,0.39081896508326114,1.5954743045989446,1.2855808712415313,-0.7799832529313712,0.5051128651347058,1.6993479647673133,0.07218715987352683,0.81500648275305,-0.24672702956312,-0.2687463774668492,2.3689750863745247,-0.4257161927970913,-0.40298195769845385,1.4275268034370876,0.5798371070730094,1.0560553218353965,-0.031820131489916866,0.37150520972870915,0.5798371070730094,2.8066316074577466,0.9713465029462117,1.089524939627866,2.1338616289497745,-0.9544453152528625,0.8676859490502526,-0.5177206708014539,1.089524939627866,-0.5177206708014539,5.129020836832448,-0.29086518455841137
| 3,069
|
Slowly progressive
| 13
| 55
| 2.301277
| 0.021376
|
Q9NR77,P50570,O95831,O00584,P41440,P02545,Q8IV08,P07196,O14979,P50402,O43707,O14773,Q99720
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,320,64,162,69,262,39,108,176,366,404,89,127
|
1326,162,89,176,2773,404,2952,1871,1408,64,262,1053,1483,108,1205,2850,2421,1084,764,2160,2424,69,860,366,320,1292,1799,1725,2030,1419,658,814,2997,2330,1063,2914,659,1089,2123,2124,1814,39,1502,714,416,2581,127,841,478,0,1898,1146,1947,805,1325
|
0.010049356609845118,1.6104528839435324,2.252883247492375,1.535084607730633,-0.9544453152528625,0.8676859490502526,-1.3779265486799217,-0.29086518455841137,-0.031820131489916866,2.5440562997072673,1.1721916646896646,0.19413417400581515,-0.07405196659429947,1.9980012684894612,0.07218715987352683,-1.056973407774157,-0.6114803864575494,0.1740206722343724,0.4100561090046764,-0.44855622173737325,-0.6114803864575494,2.519440449494305,0.33264549575231883,0.9370405358529817,1.0392326181245326,0.030850084923550944,-0.24672702956312,-0.20298328683847608,-0.3803525755016717,-0.031820131489916866,0.5239023754686642,0.37150520972870915,-1.6621699792153193,-0.540993539152877,0.19413417400581515,-1.2148568573039746,0.5239023754686642,0.1740206722343724,-0.4257161927970913,-0.4257161927970913,-0.24672702956312,3.033184055432667,-0.07405196659429947,0.46731367824728265,0.8501900582323448,-0.731248835894527,1.8723015954974838,0.35211425239127736,0.7617448151371171,5.129020836832448,-0.29086518455841137,0.13354250527191597,-0.31308432082275484,0.39081896508326114,0.030850084923550944
| 3,069
|
Molecular transducer activity
| 14
| 35
| 2.290796
| 0.021975
|
Q5KU26,Q9UNN8,P20645,Q15629,Q14108,Q9Y6I9,Q07954,Q8WTV0,P30536,P11717,O15118,Q99720,O43813,O15031
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
258,160,96,102,41,143,105,13,144,269,120,127,311,219
|
219,120,328,311,2199,1252,726,269,96,144,2203,2112,1964,105,675,1526,41,911,102,756,638,258,1000,13,3066,2043,1141,488,127,773,1779,825,1274,160,143
|
1.3015623258049298,1.9145729797153146,1.0054094308154349,1.0560553218353965,-0.4715029980224777,0.051562445642740554,0.44830289150821834,1.1557719154454555,2.1871309307140887,1.7721787798962068,-0.4715029980224777,-0.4257161927970913,-0.3354046675661042,2.039170647439996,0.5051128651347058,-0.09530566340648955,3.0221139040042435,0.2934721608296331,2.0935117653992443,0.42921722537504836,0.5426192269625886,1.1885553643741225,0.2341133298905719,3.961959193912149,-8.52404754139866,-0.3803525755016717,0.13354250527191597,0.7438593924757614,1.8723015954974838,0.4100561090046764,-0.2248062819916635,0.37150520972870915,0.051562445642740554,1.625384500578365,1.786611952471423
| 3,069
|
Vacuole organization
| 14
| 51
| 2.290037
| 0.022019
|
Q96GC9,Q8N511,Q7Z3C6,O14773,P54802,O75503,Q14108,Q9P253,P10253,P50897,P56962,Q8TBX8,Q86Y82,P11117
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
194,36,327,89,100,72,41,235,355,46,307,317,189,220
|
2674,89,1834,72,1408,520,2678,2480,2151,376,1203,651,355,220,961,458,880,2161,1414,46,2206,765,100,307,1963,996,1762,3010,41,3024,2555,941,1578,1886,327,189,36,317,1700,1743,194,1540,2702,2185,1434,1545,1974,235,2507,896,2094
|
-0.8292038872729048,2.252883247492375,-0.2687463774668492,2.494694922423651,-0.031820131489916866,0.6898018853113626,-0.8292038872729048,-0.6590388605217596,-0.44855622173737325,0.9197953633069056,0.07218715987352683,0.5239023754686642,0.9542241080917176,1.3015623258049298,0.2539802870628444,0.7795641591048054,0.3130983356211,-0.44855622173737325,-0.031820131489916866,2.9325936953118417,-0.4715029980224777,0.4100561090046764,2.1204499143061035,1.0728192976417978,-0.3354046675661042,0.2341133298905719,-0.2248062819916635,-1.7506978637026818,3.0221139040042435,-1.9325942351876662,-0.7070610806666029,0.2737663531255464,-0.11665224488806318,-0.29086518455841137,1.0223507884681426,1.458505765790809,3.228073874739091,1.0560553218353965,-0.18125720694712386,-0.20298328683847608,1.4430414108153444,-0.09530566340648955,-0.8292038872729048,-0.44855622173737325,-0.031820131489916866,-0.09530566340648955,-0.3354046675661042,1.2534569702074796,-0.6590388605217596,0.3130983356211,-0.40298195769845385
| 3,069
|
Apical plasma membrane
| 17
| 49
| 2.288839
| 0.022089
|
O43865,P41440,Q8TAD4,Q15043,Q99808,P30825,O15439,O00165,Q12959,P36551,Q8TEU7,P08183,P53985,Q16625,Q9Y6M7,P51790,O00592
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
255,69,135,264,587,73,137,612,497,558,344,53,55,184,516,414,543
|
612,2375,543,2773,137,255,1407,1520,1483,1336,53,629,2019,2352,2591,2878,1754,1640,1524,1719,1984,73,1289,992,558,2278,69,414,55,2720,2113,1842,497,1686,1160,264,2079,184,1532,135,344,1583,1392,587,1072,950,1948,954,516
|
0.5612639595076085,-0.5878723702209245,0.6534243244188832,-0.9544453152528625,1.786611952471423,1.1885553643741225,-0.031820131489916866,-0.09530566340648955,-0.07405196659429947,0.010049356609845118,2.771680946122683,0.5426192269625886,-0.3803525755016717,-0.5643770990360283,-0.7555558469531406,-1.1352868219192742,-0.2248062819916635,-0.1596272157387103,-0.09530566340648955,-0.20298328683847608,-0.35782711761202085,2.494694922423651,0.030850084923550944,0.2341133298905719,0.6351322925467491,-0.5177206708014539,2.519440449494305,0.8501900582323448,2.7009867150585474,-0.8539994760110062,-0.4257161927970913,-0.2687463774668492,0.7259074169551265,-0.18125720694712386,0.11317649001570981,1.1721916646896646,-0.40298195769845385,1.4892849674401574,-0.09530566340648955,1.801001399719216,0.9884081390522009,-0.11665224488806318,-0.010840469228635595,0.5983391977919877,0.19413417400581515,0.2737663531255464,-0.31308432082275484,0.2737663531255464,0.7078884093515075
| 3,069
|
Membrane lipid biosynthetic process
| 7
| 23
| 2.283772
| 0.022385
|
P04062,Q96G23,Q06136,Q13510,O15121,P27544,Q8NBX0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
376,141,357,175,215,277,25
|
215,778,1079,1379,2449,2017,376,1017,277,1684,357,175,2037,1577,25,1854,141,2538,427,801,2404,562,1318
|
1.3174905758707651,0.39081896508326114,0.1740206722343724,-0.010840469228635595,-0.6352021957308768,-0.3803525755016717,0.9197953633069056,0.21416484143938402,1.1392957452369128,-0.18125720694712386,0.9542241080917176,1.550253920627543,-0.3803525755016717,-0.11665224488806318,3.5158595652945293,-0.2687463774668492,1.786611952471423,-0.6829914580738592,0.8326303861028213,0.39081896508326114,-0.5878723702209245,0.6351322925467491,0.030850084923550944
| 3,069
|
Protein localization to mitochondrion
| 20
| 61
| 2.281165
| 0.022539
|
Q8N4H5,Q99595,Q15070,P30536,Q9NS69,O14737,Q9Y584,O60830,Q10713,Q8N4Q1,P55786,O14925,O95831,P62072,Q9Y6C9,Q3ZCQ8,O96008,Q8WWC4,O00165,Q5JRX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,5,399,144,20,518,153,27,536,548,54,563,64,71,611,472,614,240,612,369
|
612,1277,2674,1326,518,563,1283,830,27,2150,1601,1408,2728,2151,64,614,1955,3055,2775,1338,1838,2451,2276,144,666,2595,835,1563,730,906,54,71,2163,536,399,2660,472,1577,369,2840,130,548,1266,916,240,1369,5,1392,2668,2583,20,1146,1375,2813,647,1147,2094,1399,153,1865,611
|
0.5612639595076085,0.030850084923550944,-0.8292038872729048,0.010049356609845118,0.6898018853113626,0.6167707540458557,0.030850084923550944,0.35211425239127736,3.475825517493468,-0.44855622173737325,-0.13809249703546148,-0.031820131489916866,-0.8789201810531422,-0.44855622173737325,2.5440562997072673,0.5612639595076085,-0.3354046675661042,-3.227748904184478,-0.9544453152528625,0.010049356609845118,-0.2687463774668492,-0.6352021957308768,-0.5177206708014539,1.7721787798962068,0.5051128651347058,-0.7555558469531406,0.35211425239127736,-0.11665224488806318,0.44830289150821834,0.2934721608296331,2.7364672632965075,2.5070839778403435,-0.44855622173737325,0.6716473552783213,0.8851185038122356,-0.8045322091109726,0.7617448151371171,-0.11665224488806318,0.9370405358529817,-1.0311416178800303,1.829650134972895,0.6534243244188832,0.051562445642740554,0.2934721608296331,1.2373138262349093,0.010049356609845118,4.4424516811688495,-0.010840469228635595,-0.8045322091109726,-0.731248835894527,3.6241989583234373,0.13354250527191597,0.010049356609845118,-0.9798788971454372,0.5426192269625886,0.13354250527191597,-0.40298195769845385,-0.010840469228635595,1.6993479647673133,-0.2687463774668492,0.5798371070730094
| 3,069
|
metalloprotease
| 11
| 27
| 2.2806
| 0.022572
|
Q7Z2K6,Q8IYS1,O43847,P22695,O75844,P53582,P02786,Q5JRX3,P55786,P42892,Q9UIQ6
|
Functions
|
Panther Protein class
|
panther_protein_class
|
343,539,419,296,295,496,396,369,54,23,56
|
419,2150,295,396,2729,1522,296,2972,2239,23,2243,496,54,536,369,818,343,539,1622,869,1392,2138,2140,1710,1547,56,805
|
0.8326303861028213,-0.44855622173737325,1.089524939627866,0.8851185038122356,-0.8789201810531422,-0.09530566340648955,1.089524939627866,-1.5180231725553075,-0.4945574879422671,3.5258141843000015,-0.4945574879422671,0.7259074169551265,2.7364672632965075,0.6716473552783213,0.9370405358529817,0.37150520972870915,0.9884081390522009,0.6716473552783213,-0.13809249703546148,0.33264549575231883,-0.010840469228635595,-0.4257161927970913,-0.4257161927970913,-0.18125720694712386,-0.09530566340648955,2.7009867150585474,0.39081896508326114
| 3,069
|
Hepatic failure
| 15
| 50
| 2.27971
| 0.022625
|
P35670,O43772,O75381,P03915,P22830,P39210,P23786,P00846,Q13510,P56589,Q6NUQ1,P46100,O15118,O15460,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
224,7,170,229,12,140,236,15,175,331,180,151,120,283,376
|
1475,120,283,7,2149,170,1182,15,1556,229,376,2153,1835,1153,1337,12,236,1720,654,224,1018,140,423,1985,2835,151,2425,2571,331,908,2327,536,2764,175,2036,737,180,2533,1036,1462,2500,3049,1899,685,930,2342,1749,2614,3021,1047
|
-0.07405196659429947,1.9145729797153146,1.122762779001896,4.1654432084268365,-0.44855622173737325,1.5804484768707614,0.09272494003870865,3.7961743788849853,-0.11665224488806318,1.2534569702074796,0.9197953633069056,-0.44855622173737325,-0.2687463774668492,0.11317649001570981,0.010049356609845118,3.980016064166049,1.2373138262349093,-0.20298328683847608,0.5239023754686642,1.2855808712415313,0.21416484143938402,1.786611952471423,0.8326303861028213,-0.35782711761202085,-1.0311416178800303,1.6993479647673133,-0.6114803864575494,-0.731248835894527,1.0054094308154349,0.2934721608296331,-0.540993539152877,0.6716473552783213,-0.9291418506117229,1.550253920627543,-0.3803525755016717,0.44830289150821834,1.5046004314061265,-0.6829914580738592,0.21416484143938402,-0.05289037818638174,-0.6590388605217596,-2.5913555631402323,-0.29086518455841137,0.5051128651347058,0.2934721608296331,-0.540993539152877,-0.20298328683847608,-0.7555558469531406,-1.871225423943587,0.21416484143938402
| 3,069
|
Excessive salivation
| 8
| 26
| 2.278945
| 0.02267
|
Q9NR77,P35670,P55795,Q9BVA1,Q92796,P51812,Q03252,P46100
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,224,197,303,301,81,314,151
|
1401,2099,1556,2833,2542,652,2422,786,224,2625,151,1212,1799,1841,81,197,598,314,350,301,2789,2295,303,2297,0,1901
|
-0.031820131489916866,-0.4257161927970913,-0.11665224488806318,-1.0311416178800303,-0.7070610806666029,0.5239023754686642,-0.6114803864575494,0.39081896508326114,1.2855808712415313,-0.7799832529313712,1.6993479647673133,0.07218715987352683,-0.24672702956312,-0.2687463774668492,2.3689750863745247,1.4275268034370876,0.5798371070730094,1.0560553218353965,0.9713465029462117,1.089524939627866,-0.9544453152528625,-0.5177206708014539,1.089524939627866,-0.5177206708014539,5.129020836832448,-0.29086518455841137
| 3,069
|
Glycoside hydrolase superfamily [IPR017853]
| 10
| 15
| 2.27733
| 0.022767
|
P08195,P54802,P16278,P06865,P06280,P10253,P04066,Q9BTY2,O60502,P04062
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
629,100,101,106,483,355,578,112,242,376
|
242,376,578,483,106,651,629,1055,355,101,2973,100,1844,112,800
|
1.2211160826760208,0.9197953633069056,0.5983391977919877,0.7438593924757614,2.0254872721470325,0.5239023754686642,0.5426192269625886,0.19413417400581515,0.9542241080917176,2.0935117653992443,-1.5180231725553075,2.1204499143061035,-0.2687463774668492,1.984198193350699,0.39081896508326114
| 3,069
|
Proteasome beta-type subunit, conserved site [IPR016050]
| 6
| 8
| 2.264168
| 0.023564
|
P28070,P49720,Q99436,P28072,P49721,P28074
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
192,522,115,179,116,244
|
630,1183,192,179,244,522,116,115
|
0.5426192269625886,0.09272494003870865,1.4430414108153444,1.5046004314061265,1.2211160826760208,0.6898018853113626,1.9564707654985696,1.9703547683806868
| 3,069
|
Threonine type endopeptidase activity
| 6
| 8
| 2.264168
| 0.023564
|
P28070,P49720,Q99436,P28072,P49721,P28074
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
192,522,115,179,116,244
|
630,1183,192,179,244,522,116,115
|
0.5426192269625886,0.09272494003870865,1.4430414108153444,1.5046004314061265,1.2211160826760208,0.6898018853113626,1.9564707654985696,1.9703547683806868
| 3,069
|
Lipid transporter activity
| 7
| 22
| 2.257329
| 0.023988
|
Q96GC9,Q9H4L5,O15439,P30536,P08183,Q9Y255,O15118
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
194,304,137,144,53,281,120
|
761,120,137,53,2591,902,1017,1720,144,2242,1110,1578,2696,327,2130,194,2183,2296,2828,304,950,281
|
0.4100561090046764,1.9145729797153146,1.786611952471423,2.771680946122683,-0.7555558469531406,0.2934721608296331,0.21416484143938402,-0.20298328683847608,1.7721787798962068,-0.4945574879422671,0.15382367299729152,-0.11665224488806318,-0.8292038872729048,1.0223507884681426,-0.4257161927970913,1.4430414108153444,-0.44855622173737325,-0.5177206708014539,-1.005443892780752,1.089524939627866,0.2737663531255464,1.1392957452369128
| 3,069
|
Glycosphingolipid metabolism
| 7
| 16
| 2.248628
| 0.024536
|
P07602,P16278,P06865,Q13510,P10619,P04062,O43681
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
33,101,106,175,121,376,375
|
806,375,376,483,106,33,651,121,101,902,175,2037,2867,2046,2404,1272
|
0.37150520972870915,0.9197953633069056,0.9197953633069056,0.7438593924757614,2.0254872721470325,3.3121366390002813,0.5239023754686642,1.9145729797153146,2.0935117653992443,0.2934721608296331,1.550253920627543,-0.3803525755016717,-1.0829406177928378,-0.3803525755016717,-0.5878723702209245,0.051562445642740554
| 3,069
|
Slc mediated transmembrane transport
| 15
| 26
| 2.236475
| 0.025321
|
P08195,Q8TB61,Q15043,Q8TAD4,Q99808,P30825,Q9H2J7,P36404,Q8NEW0,Q96QD8,P35613,P53985,Q9UBX3,Q9Y6M7,Q70HW3
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
629,550,264,135,587,73,335,460,602,444,706,55,253,516,61
|
1750,2761,629,2591,1205,2416,963,73,706,460,55,2113,264,756,2696,61,602,135,550,444,587,335,253,1948,2308,516
|
-0.2248062819916635,-0.9291418506117229,0.5426192269625886,-0.7555558469531406,0.07218715987352683,-0.6114803864575494,0.2539802870628444,2.494694922423651,0.46731367824728265,0.7795641591048054,2.7009867150585474,-0.4257161927970913,1.1721916646896646,0.42921722537504836,-0.8292038872729048,2.629209225162519,0.5798371070730094,1.801001399719216,0.6534243244188832,0.81500648275305,0.5983391977919877,1.0054094308154349,1.204863382292912,-0.31308432082275484,-0.5177206708014539,0.7078884093515075
| 3,069
|
Emg neuropathic changes
| 6
| 24
| 2.227663
| 0.025903
|
Q9NR77,P07602,P39210,Q13510,O14773,P22626
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
0,33,140,175,89,349
|
2411,89,375,627,900,1408,1983,1053,33,832,2543,349,140,2071,175,2997,2252,659,2123,916,1821,2373,0,1272
|
-0.6114803864575494,2.252883247492375,0.9197953633069056,0.5426192269625886,0.2934721608296331,-0.031820131489916866,-0.35782711761202085,0.19413417400581515,3.3121366390002813,0.35211425239127736,-0.7070610806666029,0.9713465029462117,1.786611952471423,-0.40298195769845385,1.550253920627543,-1.6621699792153193,-0.4945574879422671,0.5239023754686642,-0.4257161927970913,0.2934721608296331,-0.24672702956312,-0.5643770990360283,5.129020836832448,0.051562445642740554
| 3,069
|
Apical part of cell
| 18
| 58
| 2.226611
| 0.025973
|
O43865,P41440,Q8TAD4,Q15043,Q99808,P30825,O15439,P41208,O00165,Q12959,P36551,Q8TEU7,P08183,P53985,Q16625,Q9Y6M7,P51790,O00592
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
255,69,135,264,587,73,137,297,612,497,558,344,53,55,184,516,414,543
|
612,2375,543,2773,137,2347,255,1407,1520,1483,1336,53,629,2019,2352,2591,2878,1754,1640,1524,1719,2821,1984,73,1131,1289,992,558,2278,297,69,414,55,2720,2113,1133,1842,936,497,1686,1262,1160,264,864,2079,184,1532,135,344,1583,1392,587,1072,950,1948,954,1949,516
|
0.5612639595076085,-0.5878723702209245,0.6534243244188832,-0.9544453152528625,1.786611952471423,-0.5643770990360283,1.1885553643741225,-0.031820131489916866,-0.09530566340648955,-0.07405196659429947,0.010049356609845118,2.771680946122683,0.5426192269625886,-0.3803525755016717,-0.5643770990360283,-0.7555558469531406,-1.1352868219192742,-0.2248062819916635,-0.1596272157387103,-0.09530566340648955,-0.20298328683847608,-1.005443892780752,-0.35782711761202085,2.494694922423651,0.13354250527191597,0.030850084923550944,0.2341133298905719,0.6351322925467491,-0.5177206708014539,1.089524939627866,2.519440449494305,0.8501900582323448,2.7009867150585474,-0.8539994760110062,-0.4257161927970913,0.13354250527191597,-0.2687463774668492,0.2737663531255464,0.7259074169551265,-0.18125720694712386,0.051562445642740554,0.11317649001570981,1.1721916646896646,0.33264549575231883,-0.40298195769845385,1.4892849674401574,-0.09530566340648955,1.801001399719216,0.9884081390522009,-0.11665224488806318,-0.010840469228635595,0.5983391977919877,0.19413417400581515,0.2737663531255464,-0.31308432082275484,0.2737663531255464,-0.31308432082275484,0.7078884093515075
| 3,069
|
Proteasome core complex beta subunit complex
| 6
| 7
| 2.219583
| 0.026447
|
P28070,P49720,Q99436,P28072,P49721,P28074
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
192,522,115,179,116,244
|
630,192,179,244,522,116,115
|
0.5426192269625886,1.4430414108153444,1.5046004314061265,1.2211160826760208,0.6898018853113626,1.9564707654985696,1.9703547683806868
| 3,069
|
Proteasome B-type subunit [IPR023333]
| 6
| 7
| 2.219583
| 0.026447
|
P28070,P49720,Q99436,P28072,P49721,P28074
|
Sequence
|
InterPro Family
|
interpro_family
|
192,522,115,179,116,244
|
630,192,179,244,522,116,115
|
0.5426192269625886,1.4430414108153444,1.5046004314061265,1.2211160826760208,0.6898018853113626,1.9564707654985696,1.9703547683806868
| 3,069
|
Muscle abnormality related to mitochondrial dysfunction
| 7
| 35
| 2.215333
| 0.026737
|
Q9Y2R0,P03915,P00846,O43676,Q96CU9,O96000,P00403
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,229,15,80,49,146,85
|
2875,1751,80,900,2587,613,2617,2014,146,85,15,229,1205,2799,2712,1920,1879,1292,1022,1577,1307,738,1818,2395,49,1143,531,949,2303,253,66,2306,2307,1124,955
|
-1.1352868219192742,-0.2248062819916635,2.3689750863745247,0.2934721608296331,-0.7555558469531406,0.5612639595076085,-0.7799832529313712,-0.3803525755016717,1.7577016250427588,2.3048330176200653,3.7961743788849853,1.2534569702074796,0.07218715987352683,-0.9798788971454372,-0.8539994760110062,-0.31308432082275484,-0.29086518455841137,0.030850084923550944,0.21416484143938402,-0.11665224488806318,0.030850084923550944,0.44830289150821834,-0.24672702956312,-0.5878723702209245,2.898575851463229,0.13354250527191597,0.6898018853113626,0.2737663531255464,-0.5177206708014539,1.204863382292912,2.5440562997072673,-0.5177206708014539,-0.5177206708014539,0.15382367299729152,0.2737663531255464
| 3,069
|
Horizontal nystagmus
| 6
| 24
| 2.207088
| 0.027308
|
P07602,O95831,Q9H061,P00846,Q9NSE4,O14773
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
33,64,165,15,347,89
|
2674,1326,89,2773,900,1871,64,15,376,33,505,1290,2719,1725,1646,2605,2124,1889,2437,165,347,2637,1272,826
|
-0.8292038872729048,0.010049356609845118,2.252883247492375,-0.9544453152528625,0.2934721608296331,-0.29086518455841137,2.5440562997072673,3.7961743788849853,0.9197953633069056,3.3121366390002813,0.7078884093515075,0.030850084923550944,-0.8539994760110062,-0.20298328683847608,-0.1596272157387103,-0.7555558469531406,-0.4257161927970913,-0.29086518455841137,-0.6114803864575494,1.6104528839435324,0.9884081390522009,-0.7799832529313712,0.051562445642740554,0.37150520972870915
| 3,069
|
Abnormality of the tongue
| 35
| 86
| 2.206946
| 0.027318
|
P51114,P20700,P02545,Q16637,Q96A33,P21912,P98175,P07686,O43924,P46100,Q96CV9,Q9NQT5,O15460,Q7LGA3,Q10713,Q13428,P40855,O75381,Q13510,O75844,Q9Y5P6,Q03252,O95831,O75431,P04066,P56589,Q9H4A3,Q01082,Q969G3,P16278,O60826,P61978,P10253,P07196,Q9BQT8
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
506,505,262,659,401,397,270,651,21,151,407,409,283,157,536,676,423,170,175,295,576,314,64,329,578,331,478,598,359,101,482,231,355,108,245
|
1277,1786,2411,3011,829,2707,283,21,482,960,170,329,295,1871,2511,64,1556,262,578,108,651,1484,355,1672,101,505,1719,2484,397,2543,1960,1488,423,151,2822,1386,2112,506,1564,2071,331,231,673,1221,1928,270,598,314,1684,536,1419,863,676,175,1809,1063,3024,2786,659,2631,1064,157,359,401,1743,407,2538,1369,2810,245,2137,1316,1434,478,2725,2610,409,1437,1898,1319,2008,2192,1012,576,3021,1325
|
0.030850084923550944,-0.24672702956312,-0.6114803864575494,-1.7805588252111975,0.35211425239127736,-0.8539994760110062,1.122762779001896,3.585096022897552,0.7438593924757614,0.2539802870628444,1.5804484768707614,1.0054094308154349,1.089524939627866,-0.29086518455841137,-0.6829914580738592,2.5440562997072673,-0.11665224488806318,1.1721916646896646,0.5983391977919877,1.9980012684894612,0.5239023754686642,-0.07405196659429947,0.9542241080917176,-0.18125720694712386,2.0935117653992443,0.7078884093515075,-0.20298328683847608,-0.6590388605217596,0.8851185038122356,-0.7070610806666029,-0.3354046675661042,-0.07405196659429947,0.8326303861028213,1.6993479647673133,-1.005443892780752,-0.010840469228635595,-0.4257161927970913,0.7078884093515075,-0.11665224488806318,-0.40298195769845385,1.0054094308154349,1.2534569702074796,0.5051128651347058,0.07218715987352683,-0.31308432082275484,1.1557719154454555,0.5798371070730094,1.0560553218353965,-0.18125720694712386,0.6716473552783213,-0.031820131489916866,0.33264549575231883,0.5051128651347058,1.550253920627543,-0.24672702956312,0.19413417400581515,-1.9325942351876662,-0.9544453152528625,0.5239023754686642,-0.7799832529313712,0.19413417400581515,1.6551079756873106,0.9542241080917176,0.8851185038122356,-0.20298328683847608,0.8676859490502526,-0.6829914580738592,0.010049356609845118,-0.9798788971454372,1.2211160826760208,-0.4257161927970913,0.030850084923550944,-0.031820131489916866,0.7617448151371171,-0.8539994760110062,-0.7555558469531406,0.8676859490502526,-0.031820131489916866,-0.29086518455841137,0.030850084923550944,-0.35782711761202085,-0.44855622173737325,0.2341133298905719,0.6167707540458557,-1.871225423943587,0.030850084923550944
| 3,069
|
Calcium-binding protein
| 9
| 17
| 2.20617
| 0.027372
|
Q8N163,P43307,Q8IYU8,P80303,P41208,O43852,Q02818,Q14257,Q9BPX6
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
334,173,273,48,297,139,152,30,159
|
139,3055,2108,2025,297,173,435,48,152,30,538,1817,273,334,682,159,1200
|
1.786611952471423,-3.227748904184478,-0.4257161927970913,-0.3803525755016717,1.089524939627866,1.5653751125032027,0.81500648275305,2.909942693384532,1.6993479647673133,3.3639130643678223,0.6716473552783213,-0.24672702956312,1.1557719154454555,1.0054094308154349,0.5051128651347058,1.625384500578365,0.09272494003870865
| 3,069
|
Psychosis
| 8
| 22
| 2.198571
| 0.027908
|
P03915,P51812,P36551,Q5JRX3,P00403,O15118,P16219,Q6DKK2
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
229,81,558,369,85,120,276,123
|
1277,120,85,229,2316,1485,276,2709,558,1839,566,1799,1257,81,1725,2071,369,123,1889,2581,2297,1174
|
0.030850084923550944,1.9145729797153146,2.3048330176200653,1.2534569702074796,-0.540993539152877,-0.07405196659429947,1.1392957452369128,-0.8539994760110062,0.6351322925467491,-0.2687463774668492,0.6167707540458557,-0.24672702956312,0.051562445642740554,2.3689750863745247,-0.20298328683847608,-0.40298195769845385,0.9370405358529817,1.886433964311089,-0.29086518455841137,-0.731248835894527,-0.5177206708014539,0.11317649001570981
| 3,069
|
Biliary tract abnormality
| 10
| 23
| 2.193878
| 0.028244
|
P07602,P14174,P04062,P02545,O43681,Q14108,P09601,Q5XKP0,Q10713,O96028
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
33,256,376,262,375,41,43,570,536,564
|
375,1332,564,262,376,33,43,256,2622,1919,1644,536,2764,41,600,570,2789,1036,2005,1272,2444,1147,2614
|
0.9197953633069056,0.010049356609845118,0.6167707540458557,1.1721916646896646,0.9197953633069056,3.3121366390002813,2.966365414770548,1.1885553643741225,-0.7799832529313712,-0.31308432082275484,-0.1596272157387103,0.6716473552783213,-0.9291418506117229,3.0221139040042435,0.5798371070730094,0.6167707540458557,-0.9544453152528625,0.21416484143938402,-0.35782711761202085,0.051562445642740554,-0.6114803864575494,0.13354250527191597,-0.7555558469531406
| 3,069
|
Inorganic anion transmembrane transporter activity
| 10
| 22
| 2.187979
| 0.028671
|
Q15043,O15439,P45880,Q6N075,Q9UBX3,Q8TDW0,P51790,P21796,Q9C0H2,O43681
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
264,137,28,188,253,415,414,29,94,375
|
2409,137,375,3019,29,28,414,3000,2113,2551,264,1110,188,1265,415,94,2637,253,429,2308,1949,516
|
-0.6114803864575494,1.786611952471423,0.9197953633069056,-1.871225423943587,3.3741993459998163,3.4455710952889245,0.8501900582323448,-1.6915054398535807,-0.4257161927970913,-0.7070610806666029,1.1721916646896646,0.15382367299729152,1.458505765790809,0.051562445642740554,0.8501900582323448,2.2135419004040315,-0.7799832529313712,1.204863382292912,0.8326303861028213,-0.5177206708014539,-0.31308432082275484,0.7078884093515075
| 3,069
|
Nuclear inner membrane
| 12
| 23
| 2.186992
| 0.028743
|
Q14728,Q9UH99,P20700,Q14739,P62995,Q9H1E5,Q13185,O75844,P50402,Q8IXM6,Q03252,Q99720
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
636,589,505,600,633,373,657,295,366,147,314,127
|
295,1250,505,1920,669,366,2854,633,314,657,636,600,1089,1230,2255,147,1657,2436,127,841,373,589,1593
|
1.089524939627866,0.051562445642740554,0.7078884093515075,-0.31308432082275484,0.5051128651347058,0.9370405358529817,-1.056973407774157,0.5426192269625886,1.0560553218353965,0.5239023754686642,0.5426192269625886,0.5798371070730094,0.1740206722343724,0.07218715987352683,-0.4945574879422671,1.7431802287170317,-0.1596272157387103,-0.6114803864575494,1.8723015954974838,0.35211425239127736,0.9370405358529817,0.5983391977919877,-0.11665224488806318
| 3,069
|
Mitochondrial respiratory chain complex assembly
| 8
| 41
| 2.177826
| 0.029419
|
Q9Y2R0,O95831,Q9H061,Q69YU5,O43676,Q96CU9,O96000,Q6DKK2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,64,165,98,80,49,146,123
|
2875,418,80,2148,627,2587,613,2014,1331,1151,2016,64,146,229,2712,1020,1987,2327,399,1968,2531,1231,98,123,1307,738,548,1266,1818,49,870,1143,165,2500,2303,1146,1147,66,2307,1399,955
|
-1.1352868219192742,0.8326303861028213,2.3689750863745247,-0.44855622173737325,0.5426192269625886,-0.7555558469531406,0.5612639595076085,-0.3803525755016717,0.010049356609845118,0.11317649001570981,-0.3803525755016717,2.5440562997072673,1.7577016250427588,1.2534569702074796,-0.8539994760110062,0.21416484143938402,-0.35782711761202085,-0.540993539152877,0.8851185038122356,-0.3354046675661042,-0.6829914580738592,0.07218715987352683,2.147235382078263,1.886433964311089,0.030850084923550944,0.44830289150821834,0.6534243244188832,0.051562445642740554,-0.24672702956312,2.898575851463229,0.33264549575231883,0.13354250527191597,1.6104528839435324,-0.6590388605217596,-0.5177206708014539,0.13354250527191597,0.13354250527191597,2.5440562997072673,-0.5177206708014539,-0.010840469228635595,0.2737663531255464
| 3,069
|
Organic hydroxy compound transport
| 7
| 31
| 2.175994
| 0.029556
|
Q07954,O15439,Q8WTV0,P30536,P53985,O15118,Q86Y82
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
105,137,13,144,55,120,189
|
120,137,1330,2314,1203,1410,1017,2105,1720,144,655,55,2246,105,636,1886,189,2366,13,2436,839,2665,2183,2581,2296,2828,304,1974,1318,2090,2507
|
1.9145729797153146,1.786611952471423,0.010049356609845118,-0.540993539152877,0.07218715987352683,-0.031820131489916866,0.21416484143938402,-0.4257161927970913,-0.20298328683847608,1.7721787798962068,0.5239023754686642,2.7009867150585474,-0.4945574879422671,2.039170647439996,0.5426192269625886,-0.29086518455841137,1.458505765790809,-0.5643770990360283,3.961959193912149,-0.6114803864575494,0.35211425239127736,-0.8045322091109726,-0.44855622173737325,-0.731248835894527,-0.5177206708014539,-1.005443892780752,1.089524939627866,-0.3354046675661042,0.030850084923550944,-0.40298195769845385,-0.6590388605217596
| 3,069
|
Carbohydrate derivative catabolic process
| 17
| 36
| 2.175055
| 0.029626
|
Q9NUJ1,Q13126,P54802,O60658,P16278,P06865,P06280,P04066,P00813,P35610,Q9BTY2,P15586,Q9H773,O60502,Q8TCJ2,P78549,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
322,67,100,163,101,106,483,578,16,655,112,652,183,242,475,378,376
|
2673,242,163,2847,2618,16,376,578,483,106,651,1055,652,101,902,2023,2109,655,2980,1922,1563,1211,100,378,1684,67,2749,475,1855,112,799,2582,183,322,1471,723
|
-0.8292038872729048,1.2211160826760208,1.6104528839435324,-1.056973407774157,-0.7799832529313712,3.7205314479190315,0.9197953633069056,0.5983391977919877,0.7438593924757614,2.0254872721470325,0.5239023754686642,0.19413417400581515,0.5239023754686642,2.0935117653992443,0.2934721608296331,-0.3803525755016717,-0.4257161927970913,0.5239023754686642,-1.5465213678572585,-0.31308432082275484,-0.11665224488806318,0.07218715987352683,2.1204499143061035,0.9197953633069056,-0.18125720694712386,2.5317645022419932,-0.9039672255899834,0.7617448151371171,-0.2687463774668492,1.984198193350699,0.39081896508326114,-0.731248835894527,1.5046004314061265,1.0392326181245326,-0.05289037818638174,0.46731367824728265
| 3,069
|
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.