term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitochondrial transmembrane transport
| 11
| 52
| 2.556477
| 0.010574
|
Q9Y4W6,Q99595,P00846,Q9Y619,P06576,Q9BQT8,O43772,O95831,Q8WWC4,P23786,O60830
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
298,4,36,203,293,72,13,14,305,147,28
|
2736,744,13,28,748,1807,1956,2052,2137,1692,1809,2092,14,718,36,2182,293,1812,1156,2404,324,147,1576,1358,1361,2512,2674,2237,2759,2822,1474,2838,2205,2111,2209,1724,2165,1177,305,734,2659,520,4,848,72,2972,712,2588,1252,888,298,203
|
-0.8134290501122715,0.33611163062394667,4.970267139748916,3.702904303597902,0.33611163062394667,-0.18427244054683523,-0.25603753973957905,-0.3039949440411763,-0.35204511338992117,-0.13654115282560736,-0.18427244054683523,-0.32800834772899334,4.6563469220776925,0.3595328957429135,3.273018749025682,-0.37610541469729714,0.9161413439901327,-0.18427244054683523,0.10081598985120394,-0.49676620728557386,0.8471185516552913,1.3952290840127508,-0.08889808473863031,0.006128253475181141,0.006128253475181141,-0.5694567741728175,-0.7155242386586748,-0.40018942775227584,-0.83797308570648,-0.9364275680017444,-0.04134201322447215,-0.9611119893223657,-0.37610541469729714,-0.32800834772899334,-0.37610541469729714,-0.13654115282560736,-0.35204511338992117,0.10081598985120394,0.8931505508985713,0.3595328957429135,-0.691114745586028,0.546221743136157,6.167780078048627,0.28921102773708735,2.179360380668593,-1.5119592120140046,0.38293496406007926,-0.618042899175275,0.0771753025605692,0.2657314452879552,0.9161413439901327,1.145146616611409
| 3,067
|
Abnormal muscle fiber morphology
| 18
| 67
| 2.549215
| 0.010797
|
P61978,Q9Y4W6,P00846,P03915,Q9H173,Q9HA77,Q9BTV4,Q70HW3,O95831,Q99720,P09651,P23786,P35637,Q8NI60,O43676,P22626,P06753,P50402
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
215,298,36,100,168,429,386,105,14,17,482,147,149,86,125,463,461,281
|
1396,526,125,1400,2595,2699,14,718,480,36,898,100,2802,461,1461,2772,482,1156,1024,2368,463,147,2543,794,149,2325,1703,281,1584,1416,2237,1117,2145,215,697,1884,725,2416,1078,2794,2248,2929,1231,909,105,1720,772,1376,1779,86,1177,775,1785,17,848,2994,386,2499,168,429,1100,1502,658,1255,298,2269,1563
|
-0.017596227567052123,0.522950800501484,1.5082991632477938,-0.017596227567052123,-0.6423742870091806,-0.7644228326298534,4.6563469220776925,0.3595328957429135,0.5694744024903953,3.273018749025682,0.24223217662498808,1.7781972459390094,-0.9117717140860812,0.5927088870625801,-0.04134201322447215,-0.8625447160545955,0.5694744024903953,0.10081598985120394,0.17161498562321423,-0.47258553589199437,0.5927088870625801,1.3952290840127508,-0.5937371293542618,0.31267104849579785,1.3952290840127508,-0.4484293059503235,-0.13654115282560736,0.9391154562432038,-0.08889808473863031,-0.017596227567052123,-0.40018942775227584,0.12443607605412232,-0.35204511338992117,1.0994747445642425,0.38293496406007926,-0.2081715578352066,0.3595328957429135,-0.49676620728557386,0.14803569668995656,-0.8871441784646263,-0.40018942775227584,-1.2346016602834036,0.0771753025605692,0.24223217662498808,1.688457034793547,-0.13654115282560736,0.33611163062394667,0.006128253475181141,-0.1603956915349074,1.979313777666358,0.10081598985120394,0.33611163062394667,-0.1603956915349074,4.2982861261730845,0.28921102773708735,-1.7163611225787676,0.7317400515807754,-0.5452016332533733,1.2590511132682145,0.6623043592342954,0.14803569668995656,-0.04134201322447215,0.4296819841917649,0.0771753025605692,0.9161413439901327,-0.40018942775227584,-0.06510924961463846
| 3,067
|
Microbody membrane
| 10
| 29
| 2.542622
| 0.011002
|
P56589,Q9BY49,Q9NR77,Q15067,O75381,Q9BTZ2,P33121,O14975,P28288,P39210
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
326,201,8,140,171,439,148,300,205,214
|
1258,300,1567,1260,1689,171,1754,1814,205,148,2685,214,1580,2649,1646,326,140,2339,1173,2028,1780,958,494,814,439,201,8,2221,1198
|
0.05351387697527753,0.8931505508985713,-0.08889808473863031,0.05351387697527753,-0.13654115282560736,1.2363013365837792,-0.1603956915349074,-0.18427244054683523,1.1223186256989308,1.3952290840127508,-0.7399601945456966,1.0994747445642425,-0.08889808473863031,-0.691114745586028,-0.11270866851683332,0.8471185516552913,1.4405014163205085,-0.4484293059503235,0.10081598985120394,-0.28000473103222856,-0.1603956915349074,0.21871309573559264,0.5694744024903953,0.31267104849579785,0.6391237598897699,1.145146616611409,5.4067425730737195,-0.37610541469729714,0.10081598985120394
| 3,067
|
Abnormal oral physiology
| 16
| 52
| 2.538854
| 0.011122
|
Q96CV9,Q92796,Q9NR77,Q15165,P49959,P34897,Q15233,O15460,Q92804,P09651,P35637,Q14739,Q6UN15,P06753,P50995,P46100
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
360,230,8,40,484,332,270,176,79,482,149,182,220,461,156,61
|
1148,176,1689,1810,1865,1572,461,1961,1356,1357,482,1511,2538,719,2790,332,149,941,2805,2673,1703,61,484,156,1417,1585,722,1525,2145,485,1592,1073,600,1708,949,765,1538,182,767,40,270,220,230,79,2493,360,1607,2083,1006,680,8,2815
|
0.10081598985120394,1.2135360793065495,-0.13654115282560736,-0.18427244054683523,-0.2081715578352066,-0.08889808473863031,0.5927088870625801,-0.25603753973957905,0.006128253475181141,0.006128253475181141,0.5694744024903953,-0.06510924961463846,-0.5937371293542618,0.3595328957429135,-0.8871441784646263,0.8240771578145588,1.3952290840127508,0.21871309573559264,-0.9117717140860812,-0.7155242386586748,-0.13654115282560736,2.5105058405134244,0.5694744024903953,1.304504542365476,-0.017596227567052123,-0.08889808473863031,0.3595328957429135,-0.06510924961463846,-0.35204511338992117,0.5694744024903953,-0.08889808473863031,0.14803569668995656,0.4763536252951922,-0.13654115282560736,0.21871309573559264,0.33611163062394667,-0.06510924961463846,1.2135360793065495,0.33611163062394667,3.229806250235141,0.9620729791073839,1.0994747445642425,1.0766148888424223,2.0905801244850664,-0.5452016332533733,0.7779431050658644,-0.08889808473863031,-0.3039949440411763,0.19517407509175846,0.40631795439279017,5.4067425730737195,-0.9117717140860812
| 3,067
|
Organic acid transport
| 12
| 46
| 2.527021
| 0.011503
|
Q9Y619,Q9BQT8,Q8TDW0,P08183,O43772,O15439,P23786,P33121,P30825,P14174,P41440,P53985
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
203,72,173,12,13,170,147,148,53,55,23,91
|
300,170,13,1260,1455,1956,3034,2092,1754,1909,1354,1460,2441,12,689,532,55,2366,147,205,1701,53,148,23,2674,2237,91,1525,837,3031,3016,489,2678,2111,470,173,1487,520,1840,72,2389,712,2590,1252,1850,203
|
0.8931505508985713,1.2363013365837792,4.970267139748916,0.05351387697527753,-0.04134201322447215,-0.25603753973957905,-2.343740308741473,-0.32800834772899334,-0.1603956915349074,-0.2320932034861173,0.006128253475181141,-0.04134201322447215,-0.5209715091499124,5.095325835237832,0.38293496406007926,0.522950800501484,2.5983516406440144,-0.47258553589199437,1.3952290840127508,1.1223186256989308,-0.13654115282560736,2.6422040422429265,1.3952290840127508,4.02275923887349,-0.7155242386586748,-0.40018942775227584,1.9123959679548161,-0.06510924961463846,0.28921102773708735,-2.2377862069557604,-1.975273747434785,0.5694744024903953,-0.7155242386586748,-0.32800834772899334,0.5927088870625801,1.2363013365837792,-0.04134201322447215,0.546221743136157,-0.18427244054683523,2.179360380668593,-0.47258553589199437,0.38293496406007926,-0.618042899175275,0.0771753025605692,-0.18427244054683523,1.145146616611409
| 3,067
|
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
| 9
| 14
| 2.520432
| 0.011721
|
Q13217,P07237,Q86UP2,Q07065,P07942,Q02818,Q15084,O43852,Q15293
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
193,256,492,357,250,302,207,122,411
|
122,256,250,1265,1213,2646,302,357,193,207,411,1232,492,583
|
1.530869168826082,0.9850140031000338,1.0079386178201262,0.05351387697527753,0.0771753025605692,-0.691114745586028,0.8931505508985713,0.7779431050658644,1.1679588008379829,1.1223186256989308,0.6854672060130802,0.0771753025605692,0.5694744024903953,0.4996614648715897
| 3,067
|
Tetratricopeptide-like helical domain superfamily [IPR011990]
| 12
| 80
| 2.515485
| 0.011887
|
Q13217,Q9NSK0,Q7L5D6,O15091,Q92791,O75718,Q5R3I4,Q32P28,O15460,P13674,Q6DKK2,O75153
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
193,162,195,164,5,6,172,48,176,244,153,31
|
1054,1016,1056,1395,2225,164,1953,176,1351,1058,1108,687,31,6,2621,1692,1753,2181,244,1760,1762,1877,1070,1161,1162,1820,2675,1824,2021,1977,2062,2063,2297,1774,1282,193,2517,2934,1372,1169,1284,1980,2781,2071,48,172,153,1041,2162,702,195,649,625,5,1092,1293,455,382,1989,814,1789,1342,850,629,2045,2501,275,713,162,854,1740,636,782,1849,1742,2178,927,560,716,2980
|
0.14803569668995656,0.17161498562321423,0.14803569668995656,-0.017596227567052123,-0.40018942775227584,1.2590511132682145,-0.25603753973957905,1.2135360793065495,0.006128253475181141,0.14803569668995656,0.12443607605412232,0.38293496406007926,3.617246030299946,5.592772581581793,-0.6667314992911156,-0.13654115282560736,-0.1603956915349074,-0.37610541469729714,1.030846911961832,-0.1603956915349074,-0.1603956915349074,-0.2081715578352066,0.14803569668995656,0.10081598985120394,0.10081598985120394,-0.18427244054683523,-0.7155242386586748,-0.18427244054683523,-0.28000473103222856,-0.25603753973957905,-0.3039949440411763,-0.3039949440411763,-0.4242973311338641,-0.1603956915349074,0.05351387697527753,1.1679588008379829,-0.5694567741728175,-1.2596499307860836,0.006128253475181141,0.10081598985120394,0.05351387697527753,-0.25603753973957905,-0.8625447160545955,-0.3039949440411763,2.795323733143928,1.2363013365837792,1.3272083516406563,0.17161498562321423,-0.35204511338992117,0.38293496406007926,1.1679588008379829,0.4296819841917649,0.4530271695640074,5.716460207824872,0.14803569668995656,0.05351387697527753,0.6159253041543369,0.7317400515807754,-0.25603753973957905,0.31267104849579785,-0.1603956915349074,0.029831574171165644,0.28921102773708735,0.4530271695640074,-0.28000473103222856,-0.5452016332533733,0.9620729791073839,0.38293496406007926,1.304504542365476,0.28921102773708735,-0.13654115282560736,0.4530271695640074,0.33611163062394667,-0.18427244054683523,-0.13654115282560736,-0.35204511338992117,0.24223217662498808,0.522950800501484,0.38293496406007926,-1.5628376619481128
| 3,067
|
Serine/threonine-protein kinase, active site [IPR008271]
| 7
| 41
| 2.498771
| 0.012462
|
Q96GD4,Q14004,P49840,P49841,P53350,P06493,P24941
|
Sequence
|
InterPro Active site
|
interpro_active_site
|
65,38,11,46,88,25,26
|
363,2670,2007,25,1698,366,2598,1872,2282,155,26,2756,1068,2685,1818,11,46,722,88,1976,1222,1328,392,1594,2335,2244,38,1713,426,994,1330,2783,1781,65,1939,1676,2984,1488,711,2765,965
|
0.7548502524793712,-0.7155242386586748,-0.28000473103222856,3.95895741112925,-0.13654115282560736,0.7548502524793712,-0.6423742870091806,-0.2081715578352066,-0.4242973311338641,1.304504542365476,3.9163763942062166,-0.83797308570648,0.14803569668995656,-0.7399601945456966,-0.18427244054683523,5.157748552028619,2.9478894554497037,0.3595328957429135,1.9570211264778132,-0.25603753973957905,0.0771753025605692,0.029831574171165644,0.7086124029290911,-0.08889808473863031,-0.4484293059503235,-0.40018942775227584,3.273018749025682,-0.13654115282560736,0.6623043592342954,0.19517407509175846,0.029831574171165644,-0.8625447160545955,-0.1603956915349074,2.312151123677215,-0.2320932034861173,-0.11270866851683332,-1.588331377422339,-0.04134201322447215,0.38293496406007926,-0.83797308570648,0.21871309573559264
| 3,067
|
non-receptor serine/threonine protein kinase
| 8
| 47
| 2.487327
| 0.012871
|
Q96GD4,O14874,Q14004,P49840,P49841,P53350,P06493,P24941
|
Functions
|
Panther Protein class
|
panther_protein_class
|
65,101,38,11,46,88,25,26
|
101,2319,2670,2277,2007,25,1698,366,2598,1872,155,26,2756,1068,2685,1877,1818,11,46,88,2241,1976,1222,2414,1328,392,1594,2934,2335,2244,38,1713,2712,2732,994,1330,2783,2680,65,1939,1676,1488,2172,2765,965,1998,2695
|
1.7333549222805171,-0.4484293059503235,-0.7155242386586748,-0.4242973311338641,-0.28000473103222856,3.95895741112925,-0.13654115282560736,0.7548502524793712,-0.6423742870091806,-0.2081715578352066,1.304504542365476,3.9163763942062166,-0.83797308570648,0.14803569668995656,-0.7399601945456966,-0.2081715578352066,-0.18427244054683523,5.157748552028619,2.9478894554497037,1.9570211264778132,-0.40018942775227584,-0.25603753973957905,0.0771753025605692,-0.49676620728557386,0.029831574171165644,0.7086124029290911,-0.08889808473863031,-1.2596499307860836,-0.4484293059503235,-0.40018942775227584,3.273018749025682,-0.13654115282560736,-0.7644228326298534,-0.7889123757164783,0.19517407509175846,0.029831574171165644,-0.8625447160545955,-0.7155242386586748,2.312151123677215,-0.2320932034861173,-0.11270866851683332,-0.04134201322447215,-0.35204511338992117,-0.83797308570648,0.21871309573559264,-0.25603753973957905,-0.7399601945456966
| 3,067
|
Steroid metabolism
| 8
| 22
| 2.480573
| 0.013117
|
P35610,Q15392,P37268,Q16850,Q14739,Q9UBM7,Q15126,Q9UHB6
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
102,77,139,50,182,289,246,127
|
291,828,1863,1694,1263,1157,1316,102,139,1771,2710,2779,182,246,77,1657,538,50,2764,289,127,2532
|
0.9161413439901327,0.28921102773708735,-0.2081715578352066,-0.13654115282560736,0.05351387697527753,0.10081598985120394,0.029831574171165644,1.7333549222805171,1.4405014163205085,-0.1603956915349074,-0.7644228326298534,-0.8625447160545955,1.2135360793065495,1.030846911961832,2.0905801244850664,-0.11270866851683332,0.522950800501484,2.7297697351237553,-0.83797308570648,0.9391154562432038,1.5082991632477938,-0.5694567741728175
| 3,067
|
Negative regulation of mrna splicing via spliceosome
| 6
| 15
| 2.480428
| 0.013122
|
P61978,Q13242,Q16629,O75494,P38159,P98175
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
215,340,327,108,109,408
|
1451,108,463,1759,1359,109,215,408,904,802,1534,340,1034,327,1133
|
-0.04134201322447215,1.665987090283156,0.5927088870625801,-0.1603956915349074,0.006128253475181141,1.6435030564502273,1.0994747445642425,0.6854672060130802,0.24223217662498808,0.31267104849579785,-0.06510924961463846,0.8010187077276009,0.17161498562321423,0.8471185516552913,0.12443607605412232
| 3,067
|
Protein kinase activity
| 17
| 76
| 2.477609
| 0.013227
|
Q96GD4,P07948,Q12792,O14874,Q14004,O14936,P49840,Q13464,P49841,P25440,P17252,O14976,Q8NI60,P53350,P06493,P24941,P21127
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
65,403,163,101,38,255,11,392,46,238,366,363,86,88,25,26,155
|
101,255,363,527,2319,747,2670,662,2277,2007,25,403,2183,1314,2843,1698,366,2598,1872,2282,155,1407,26,238,2756,2283,1068,2685,1966,1877,1818,11,46,722,88,835,987,2241,1976,1222,1280,163,2414,1328,948,839,392,1594,2934,2335,2244,38,1713,2712,2732,1540,426,994,1330,1602,2783,2680,86,1781,65,1939,1676,2984,1488,2172,711,2765,852,965,1998,1498
|
1.7333549222805171,0.9850140031000338,0.7548502524793712,0.522950800501484,-0.4484293059503235,0.33611163062394667,-0.7155242386586748,0.40631795439279017,-0.4242973311338641,-0.28000473103222856,3.95895741112925,0.6854672060130802,-0.37610541469729714,0.029831574171165644,-0.9858252312843699,-0.13654115282560736,0.7548502524793712,-0.6423742870091806,-0.2081715578352066,-0.4242973311338641,1.304504542365476,-0.017596227567052123,3.9163763942062166,1.0537389733278402,-0.83797308570648,-0.4242973311338641,0.14803569668995656,-0.7399601945456966,-0.25603753973957905,-0.2081715578352066,-0.18427244054683523,5.157748552028619,2.9478894554497037,0.3595328957429135,1.9570211264778132,0.28921102773708735,0.19517407509175846,-0.40018942775227584,-0.25603753973957905,0.0771753025605692,0.05351387697527753,1.2817854889267128,-0.49676620728557386,0.029831574171165644,0.21871309573559264,0.28921102773708735,0.7086124029290911,-0.08889808473863031,-1.2596499307860836,-0.4484293059503235,-0.40018942775227584,3.273018749025682,-0.13654115282560736,-0.7644228326298534,-0.7889123757164783,-0.06510924961463846,0.6623043592342954,0.19517407509175846,0.029831574171165644,-0.08889808473863031,-0.8625447160545955,-0.7155242386586748,1.979313777666358,-0.1603956915349074,2.312151123677215,-0.2320932034861173,-0.11270866851683332,-1.588331377422339,-0.04134201322447215,-0.35204511338992117,0.38293496406007926,-0.83797308570648,0.28921102773708735,0.21871309573559264,-0.25603753973957905,-0.04134201322447215
| 3,067
|
Chromosome condensation
| 8
| 23
| 2.475154
| 0.013318
|
P10412,P07305,O95831,P16403,O43823,P53350,P06493,P84243
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,322,14,483,266,88,25,407
|
266,1107,2471,1959,14,25,322,128,1404,640,483,88,407,1172,2711,729,999,2306,554,1137,1498,1499,1901
|
0.9620729791073839,0.12443607605412232,-0.5452016332533733,-0.25603753973957905,4.6563469220776925,3.95895741112925,0.8471185516552913,1.4857145839161021,-0.017596227567052123,0.4296819841917649,0.5694744024903953,1.9570211264778132,0.6854672060130802,0.10081598985120394,-0.7644228326298534,0.3595328957429135,0.19517407509175846,-0.4242973311338641,0.522950800501484,0.12443607605412232,-0.04134201322447215,-0.04134201322447215,-0.2081715578352066
| 3,067
|
Protein serine threonine kinase activity
| 14
| 61
| 2.471728
| 0.013446
|
Q96GD4,O14874,Q14004,O14936,P49840,Q13464,P49841,P25440,P17252,O14976,P53350,P06493,P24941,P21127
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
65,101,38,255,11,392,46,238,366,363,88,25,26,155
|
101,255,363,2319,747,2670,662,2277,2007,25,2183,1314,1698,366,2598,1872,2282,155,26,238,2756,1068,2685,1877,1818,11,46,722,88,835,987,2241,1976,1222,2414,1328,392,1594,2934,2335,2244,38,1713,2732,426,994,1330,1602,2783,2680,1781,65,1939,1676,2984,1488,2172,711,2765,965,1998
|
1.7333549222805171,0.9850140031000338,0.7548502524793712,-0.4484293059503235,0.33611163062394667,-0.7155242386586748,0.40631795439279017,-0.4242973311338641,-0.28000473103222856,3.95895741112925,-0.37610541469729714,0.029831574171165644,-0.13654115282560736,0.7548502524793712,-0.6423742870091806,-0.2081715578352066,-0.4242973311338641,1.304504542365476,3.9163763942062166,1.0537389733278402,-0.83797308570648,0.14803569668995656,-0.7399601945456966,-0.2081715578352066,-0.18427244054683523,5.157748552028619,2.9478894554497037,0.3595328957429135,1.9570211264778132,0.28921102773708735,0.19517407509175846,-0.40018942775227584,-0.25603753973957905,0.0771753025605692,-0.49676620728557386,0.029831574171165644,0.7086124029290911,-0.08889808473863031,-1.2596499307860836,-0.4484293059503235,-0.40018942775227584,3.273018749025682,-0.13654115282560736,-0.7889123757164783,0.6623043592342954,0.19517407509175846,0.029831574171165644,-0.08889808473863031,-0.8625447160545955,-0.7155242386586748,-0.1603956915349074,2.312151123677215,-0.2320932034861173,-0.11270866851683332,-1.588331377422339,-0.04134201322447215,-0.35204511338992117,0.38293496406007926,-0.83797308570648,0.21871309573559264,-0.25603753973957905
| 3,067
|
Abnormality of salivation
| 13
| 40
| 2.470895
| 0.013478
|
Q96CV9,Q92796,Q9NR77,Q15165,P49959,P34897,Q15233,Q92804,P09651,P35637,Q14739,P50995,P46100
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
360,230,8,40,484,332,270,79,482,149,182,156,61
|
1148,1689,1810,1865,1961,1357,482,1511,719,2790,332,149,941,2673,1703,61,484,156,1417,1585,722,1525,2145,485,1592,600,1708,765,182,40,270,230,79,2493,360,1607,2083,1006,8,2815
|
0.10081598985120394,-0.13654115282560736,-0.18427244054683523,-0.2081715578352066,-0.25603753973957905,0.006128253475181141,0.5694744024903953,-0.06510924961463846,0.3595328957429135,-0.8871441784646263,0.8240771578145588,1.3952290840127508,0.21871309573559264,-0.7155242386586748,-0.13654115282560736,2.5105058405134244,0.5694744024903953,1.304504542365476,-0.017596227567052123,-0.08889808473863031,0.3595328957429135,-0.06510924961463846,-0.35204511338992117,0.5694744024903953,-0.08889808473863031,0.4763536252951922,-0.13654115282560736,0.33611163062394667,1.2135360793065495,3.229806250235141,0.9620729791073839,1.0766148888424223,2.0905801244850664,-0.5452016332533733,0.7779431050658644,-0.08889808473863031,-0.3039949440411763,0.19517407509175846,5.4067425730737195,-0.9117717140860812
| 3,067
|
Xerostomia
| 6
| 14
| 2.460557
| 0.013872
|
Q96CV9,Q15165,Q92804,P35637,Q14739,P50995
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
360,40,79,149,182,156
|
1810,1961,482,149,1703,156,1525,2145,1708,765,182,40,79,360
|
-0.18427244054683523,-0.25603753973957905,0.5694744024903953,1.3952290840127508,-0.13654115282560736,1.304504542365476,-0.06510924961463846,-0.35204511338992117,-0.13654115282560736,0.33611163062394667,1.2135360793065495,3.229806250235141,2.0905801244850664,0.7779431050658644
| 3,067
|
Negative regulation of mrna processing
| 8
| 21
| 2.444577
| 0.014502
|
P61978,Q13242,Q16629,O75494,P38159,P18615,P22626,P98175
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
215,340,327,108,109,390,463,408
|
1951,1451,1626,108,390,463,1759,1359,109,215,408,904,802,1534,340,1034,327,541,1041,1287,1133
|
-0.25603753973957905,-0.04134201322447215,-0.11270866851683332,1.665987090283156,0.7086124029290911,0.5927088870625801,-0.1603956915349074,0.006128253475181141,1.6435030564502273,1.0994747445642425,0.6854672060130802,0.24223217662498808,0.31267104849579785,-0.06510924961463846,0.8010187077276009,0.17161498562321423,0.8471185516552913,0.522950800501484,0.17161498562321423,0.05351387697527753,0.12443607605412232
| 3,067
|
Fatigable weakness of bulbar muscles
| 6
| 14
| 2.425787
| 0.015275
|
Q96CV9,Q15165,Q92804,P35637,P06753,P50995
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
360,40,79,149,461,156
|
1810,461,1961,482,149,1703,156,2145,1708,765,40,79,360,1563
|
-0.18427244054683523,0.5927088870625801,-0.25603753973957905,0.5694744024903953,1.3952290840127508,-0.13654115282560736,1.304504542365476,-0.35204511338992117,-0.13654115282560736,0.33611163062394667,3.229806250235141,2.0905801244850664,0.7779431050658644,-0.06510924961463846
| 3,067
|
Protein kinase domain [IPR000719]
| 13
| 50
| 2.414098
| 0.015774
|
Q96GD4,P07948,Q14004,O14936,P49840,Q13464,P49841,P17252,O14976,P53350,P06493,P24941,P21127
|
Sequence
|
InterPro Domain
|
interpro_domain
|
65,403,38,255,11,392,46,366,363,88,25,26,155
|
255,363,2670,2277,2007,25,403,1698,366,2598,1872,2282,155,26,2756,1068,2685,1966,1818,11,46,722,88,1976,1222,2414,1328,839,392,1594,2335,2244,38,1713,1540,426,994,1330,2783,2680,1781,65,1939,1676,2984,1488,711,2765,965,1998
|
0.9850140031000338,0.7548502524793712,-0.7155242386586748,-0.4242973311338641,-0.28000473103222856,3.95895741112925,0.6854672060130802,-0.13654115282560736,0.7548502524793712,-0.6423742870091806,-0.2081715578352066,-0.4242973311338641,1.304504542365476,3.9163763942062166,-0.83797308570648,0.14803569668995656,-0.7399601945456966,-0.25603753973957905,-0.18427244054683523,5.157748552028619,2.9478894554497037,0.3595328957429135,1.9570211264778132,-0.25603753973957905,0.0771753025605692,-0.49676620728557386,0.029831574171165644,0.28921102773708735,0.7086124029290911,-0.08889808473863031,-0.4484293059503235,-0.40018942775227584,3.273018749025682,-0.13654115282560736,-0.06510924961463846,0.6623043592342954,0.19517407509175846,0.029831574171165644,-0.8625447160545955,-0.7155242386586748,-0.1603956915349074,2.312151123677215,-0.2320932034861173,-0.11270866851683332,-1.588331377422339,-0.04134201322447215,0.38293496406007926,-0.83797308570648,0.21871309573559264,-0.25603753973957905
| 3,067
|
Apc c mediated degradation of cell cycle proteins
| 7
| 60
| 2.389007
| 0.016894
|
Q96GD4,P28070,P53350,P06493,P24941,P49721,Q99436
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
65,44,88,25,26,60,62
|
1056,1565,2903,1857,1952,1351,2698,2319,1862,2507,25,860,2054,976,26,2185,1466,1467,1873,2186,44,2998,129,1760,2445,2327,2448,1363,60,2290,88,2196,1365,2331,1825,2019,2332,2150,2152,1282,2107,1035,1535,1711,2336,1980,1776,417,273,65,62,1841,2123,1740,636,782,1846,2533,2831,1620
|
0.14803569668995656,-0.08889808473863031,-1.1846005429298558,-0.2081715578352066,-0.25603753973957905,0.006128253475181141,-0.7644228326298534,-0.4484293059503235,-0.2081715578352066,-0.5694567741728175,3.95895741112925,0.2657314452879552,-0.3039949440411763,0.19517407509175846,3.9163763942062166,-0.37610541469729714,-0.04134201322447215,-0.04134201322447215,-0.2081715578352066,-0.37610541469729714,3.0999160722803394,-1.7678418524139115,1.4857145839161021,-0.1603956915349074,-0.5209715091499124,-0.4484293059503235,-0.5209715091499124,0.006128253475181141,2.5544523677537962,-0.4242973311338641,1.9570211264778132,-0.37610541469729714,0.006128253475181141,-0.4484293059503235,-0.18427244054683523,-0.28000473103222856,-0.4484293059503235,-0.35204511338992117,-0.35204511338992117,0.05351387697527753,-0.32800834772899334,0.17161498562321423,-0.06510924961463846,-0.13654115282560736,-0.4484293059503235,-0.25603753973957905,-0.1603956915349074,0.6854672060130802,0.9620729791073839,2.312151123677215,2.4004302172902574,-0.18427244054683523,-0.32800834772899334,-0.13654115282560736,0.4530271695640074,0.33611163062394667,-0.18427244054683523,-0.5694567741728175,-0.9364275680017444,-0.08889808473863031
| 3,067
|
Protein kinase
| 14
| 60
| 2.371836
| 0.0177
|
Q96GD4,P07948,O14874,Q14004,O14936,P49840,Q13464,P49841,P17252,O14976,P53350,P06493,P24941,P21127
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
65,403,101,38,255,11,392,46,366,363,88,25,26,155
|
101,255,363,2319,2670,2277,2007,25,403,1698,366,2598,1872,2282,155,26,2756,1068,2685,1966,1877,1818,11,46,722,88,835,987,2241,1976,1222,2414,1328,839,392,1594,2934,2335,2244,38,1713,2712,2732,1540,426,994,1330,2783,2680,1781,65,1939,1676,2984,1488,2172,711,2765,965,1998
|
1.7333549222805171,0.9850140031000338,0.7548502524793712,-0.4484293059503235,-0.7155242386586748,-0.4242973311338641,-0.28000473103222856,3.95895741112925,0.6854672060130802,-0.13654115282560736,0.7548502524793712,-0.6423742870091806,-0.2081715578352066,-0.4242973311338641,1.304504542365476,3.9163763942062166,-0.83797308570648,0.14803569668995656,-0.7399601945456966,-0.25603753973957905,-0.2081715578352066,-0.18427244054683523,5.157748552028619,2.9478894554497037,0.3595328957429135,1.9570211264778132,0.28921102773708735,0.19517407509175846,-0.40018942775227584,-0.25603753973957905,0.0771753025605692,-0.49676620728557386,0.029831574171165644,0.28921102773708735,0.7086124029290911,-0.08889808473863031,-1.2596499307860836,-0.4484293059503235,-0.40018942775227584,3.273018749025682,-0.13654115282560736,-0.7644228326298534,-0.7889123757164783,-0.06510924961463846,0.6623043592342954,0.19517407509175846,0.029831574171165644,-0.8625447160545955,-0.7155242386586748,-0.1603956915349074,2.312151123677215,-0.2320932034861173,-0.11270866851683332,-1.588331377422339,-0.04134201322447215,-0.35204511338992117,0.38293496406007926,-0.83797308570648,0.21871309573559264,-0.25603753973957905
| 3,067
|
Abnormal circulating dicarboxylic acid concentration
| 9
| 41
| 2.367972
| 0.017886
|
P36551,P22695,P37268,P23786,P28288,Q14739,P41440,P55263,P48735
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
258,197,139,147,205,182,23,56,90
|
255,2819,2536,2324,2772,532,1403,2508,1573,1265,2055,1406,197,147,205,258,139,1409,1580,23,2757,90,1585,1117,56,1592,1073,182,1542,1717,2164,1605,1094,1553,681,1302,2354,2432,1390,1252,2269
|
0.9850140031000338,-0.9364275680017444,-0.5937371293542618,-0.4484293059503235,-0.8625447160545955,0.522950800501484,-0.017596227567052123,-0.5694567741728175,-0.08889808473863031,0.05351387697527753,-0.3039949440411763,-0.017596227567052123,1.145146616611409,1.3952290840127508,1.1223186256989308,0.9850140031000338,1.4405014163205085,-0.017596227567052123,-0.08889808473863031,4.02275923887349,-0.83797308570648,1.9347152099627174,-0.08889808473863031,0.12443607605412232,2.5983516406440144,-0.08889808473863031,0.14803569668995656,1.2135360793065495,-0.06510924961463846,-0.13654115282560736,-0.35204511338992117,-0.08889808473863031,0.14803569668995656,-0.06510924961463846,0.40631795439279017,0.05351387697527753,-0.4484293059503235,-0.49676620728557386,0.006128253475181141,0.0771753025605692,-0.40018942775227584
| 3,067
|
Negative regulation of rna splicing
| 7
| 17
| 2.367699
| 0.017899
|
P61978,Q13242,Q16629,O75494,P38159,Q9UKA9,P98175
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
215,340,327,108,109,318,408
|
1451,108,463,1759,1359,109,215,2483,408,904,802,1534,340,1034,327,1133,318
|
-0.04134201322447215,1.665987090283156,0.5927088870625801,-0.1603956915349074,0.006128253475181141,1.6435030564502273,1.0994747445642425,-0.5452016332533733,0.6854672060130802,0.24223217662498808,0.31267104849579785,-0.06510924961463846,0.8010187077276009,0.17161498562321423,0.8471185516552913,0.12443607605412232,0.8701429845725451
| 3,067
|
Protein serine threonine tyrosine kinase activity
| 13
| 56
| 2.366032
| 0.01798
|
Q96GD4,P07948,Q14004,O14936,P49840,Q13464,P49841,P17252,O14976,P53350,P06493,P24941,P21127
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
65,403,38,255,11,392,46,366,363,88,25,26,155
|
255,363,2319,2670,2277,2007,25,403,2183,1698,366,2598,1872,2282,155,26,2756,1068,2685,1966,1877,1818,11,46,722,88,2241,1976,1222,2414,1328,392,1594,2934,2335,2244,38,1713,1540,426,994,1330,1602,2783,1781,65,1939,1676,2984,1488,2172,711,2765,852,965,1498
|
0.9850140031000338,0.7548502524793712,-0.4484293059503235,-0.7155242386586748,-0.4242973311338641,-0.28000473103222856,3.95895741112925,0.6854672060130802,-0.37610541469729714,-0.13654115282560736,0.7548502524793712,-0.6423742870091806,-0.2081715578352066,-0.4242973311338641,1.304504542365476,3.9163763942062166,-0.83797308570648,0.14803569668995656,-0.7399601945456966,-0.25603753973957905,-0.2081715578352066,-0.18427244054683523,5.157748552028619,2.9478894554497037,0.3595328957429135,1.9570211264778132,-0.40018942775227584,-0.25603753973957905,0.0771753025605692,-0.49676620728557386,0.029831574171165644,0.7086124029290911,-0.08889808473863031,-1.2596499307860836,-0.4484293059503235,-0.40018942775227584,3.273018749025682,-0.13654115282560736,-0.06510924961463846,0.6623043592342954,0.19517407509175846,0.029831574171165644,-0.08889808473863031,-0.8625447160545955,-0.1603956915349074,2.312151123677215,-0.2320932034861173,-0.11270866851683332,-1.588331377422339,-0.04134201322447215,-0.35204511338992117,0.38293496406007926,-0.83797308570648,0.28921102773708735,0.21871309573559264,-0.04134201322447215
| 3,067
|
Cholesterol metabolism with bloch and kandutschrussell pathways
| 9
| 21
| 2.362713
| 0.018142
|
P35610,P37268,Q15392,Q16850,Q9BWD1,P33121,Q14739,Q9UBM7,Q15126
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
102,139,77,50,114,148,182,289,246
|
1689,1754,301,1157,148,102,139,943,2478,2999,2710,2779,1122,182,246,77,1657,538,50,114,289
|
-0.13654115282560736,-0.1603956915349074,0.8931505508985713,0.10081598985120394,1.3952290840127508,1.7333549222805171,1.4405014163205085,0.21871309573559264,-0.5452016332533733,-1.7678418524139115,-0.7644228326298534,-0.8625447160545955,0.12443607605412232,1.2135360793065495,1.030846911961832,2.0905801244850664,-0.11270866851683332,0.522950800501484,2.7297697351237553,1.6210048659429874,0.9391154562432038
| 3,067
|
Organic anion transmembrane transporter activity
| 7
| 32
| 2.356776
| 0.018434
|
Q14728,Q9BQT8,O15439,Q99808,P30825,P41440,P53985
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
68,72,170,82,53,23,91
|
2924,170,1260,1956,2092,2182,689,532,1156,2404,53,23,2237,91,837,68,489,1658,2678,470,1667,520,1840,82,72,712,2125,2590,1252,1850,203,1564
|
-1.2346016602834036,1.2363013365837792,0.05351387697527753,-0.25603753973957905,-0.32800834772899334,-0.37610541469729714,0.38293496406007926,0.522950800501484,0.10081598985120394,-0.49676620728557386,2.6422040422429265,4.02275923887349,-0.40018942775227584,1.9123959679548161,0.28921102773708735,2.2679375802329096,0.5694744024903953,-0.11270866851683332,-0.7155242386586748,0.5927088870625801,-0.11270866851683332,0.546221743136157,-0.18427244054683523,2.0683529149150766,2.179360380668593,0.38293496406007926,-0.32800834772899334,-0.618042899175275,0.0771753025605692,-0.18427244054683523,1.145146616611409,-0.06510924961463846
| 3,067
|
Alcohol metabolic process
| 17
| 75
| 2.336112
| 0.019485
|
Q9NX62,P34913,P35610,O94788,Q9BY49,Q10713,P37268,Q15392,P30837,Q16850,Q9UBM7,Q14739,Q15126,Q9BW91,P48735,Q8WTV0,Q9UHB6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
263,98,102,7,201,228,139,77,16,50,289,182,246,286,90,27,127
|
2640,291,2318,1859,2940,857,563,828,931,7,1863,2906,1510,1694,1263,752,1357,2508,2597,1157,2789,2364,936,2891,1316,16,98,597,102,139,1518,2510,943,90,982,1645,2101,1417,2649,2514,2999,2708,2728,1771,2961,2710,228,2761,620,2779,1122,182,246,77,1657,538,1777,50,514,2031,2850,1378,27,2617,2214,439,286,201,739,2896,263,1995,289,127,613
|
-0.691114745586028,0.9161413439901327,-0.4484293059503235,-0.2081715578352066,-1.2847304228470318,0.2657314452879552,0.4996614648715897,0.28921102773708735,0.21871309573559264,5.4067425730737195,-0.2081715578352066,-1.1846005429298558,-0.06510924961463846,-0.13654115282560736,0.05351387697527753,0.33611163062394667,0.006128253475181141,-0.5694567741728175,-0.6423742870091806,0.10081598985120394,-0.8871441784646263,-0.47258553589199437,0.21871309573559264,-1.109832915775756,0.029831574171165644,4.467095124957466,1.8005977335130876,0.4763536252951922,1.7333549222805171,1.4405014163205085,-0.06510924961463846,-0.5694567741728175,0.21871309573559264,1.9347152099627174,0.19517407509175846,-0.11270866851683332,-0.32800834772899334,-0.017596227567052123,-0.691114745586028,-0.5694567741728175,-1.7678418524139115,-0.7644228326298534,-0.7889123757164783,-0.1603956915349074,-1.410627524712207,-0.7644228326298534,1.0766148888424223,-0.83797308570648,0.4530271695640074,-0.8625447160545955,0.12443607605412232,1.2135360793065495,1.030846911961832,2.0905801244850664,-0.11270866851683332,0.522950800501484,-0.1603956915349074,2.7297697351237553,0.546221743136157,-0.28000473103222856,-0.9858252312843699,0.006128253475181141,3.8737579156642066,-0.6423742870091806,-0.37610541469729714,0.6391237598897699,0.9391154562432038,1.145146616611409,0.3595328957429135,-1.109832915775756,0.9850140031000338,-0.25603753973957905,0.9391154562432038,1.5082991632477938,0.4763536252951922
| 3,067
|
Positive regulation of mitochondrion organization
| 6
| 22
| 2.329277
| 0.019844
|
P21796,P49840,P49841,P27544,Q96A26,Q9GZY8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
324,11,46,84,283,317
|
1856,1507,1063,2182,1313,1156,324,84,2097,2877,1030,11,46,1544,2165,283,812,2081,2617,317,714,387
|
-0.2081715578352066,-0.06510924961463846,0.14803569668995656,-0.37610541469729714,0.029831574171165644,0.10081598985120394,0.8471185516552913,2.0238595222072155,-0.32800834772899334,-1.060140477409233,0.17161498562321423,5.157748552028619,2.9478894554497037,-0.06510924961463846,-0.35204511338992117,0.9391154562432038,0.31267104849579785,-0.3039949440411763,-0.6423742870091806,0.8701429845725451,0.38293496406007926,0.7317400515807754
| 3,067
|
Negative regulation of cell cycle process
| 14
| 70
| 2.302498
| 0.021307
|
Q96GD4,Q9Y619,Q96RU2,P49454,Q96DY7,Q96K76,Q6IQ49,Q8N6R0,Q96PK6,P46100,P53350,P06493,P24941,Q68E01
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,203,233,198,75,316,240,111,146,61,88,25,26,188
|
2226,2091,1106,2698,2750,1107,2319,1061,1627,1063,2507,25,1572,323,860,1867,754,26,433,1411,1764,61,198,484,984,88,1526,2241,2760,2731,724,1475,805,1035,2934,2108,2416,1925,2246,1081,2490,2337,188,240,808,1333,2887,1888,730,111,1725,2424,75,1181,65,1046,316,146,918,233,737,1731,2955,634,2558,1498,1848,2950,203,1798
|
-0.40018942775227584,-0.32800834772899334,0.12443607605412232,-0.7644228326298534,-0.83797308570648,0.12443607605412232,-0.4484293059503235,0.14803569668995656,-0.11270866851683332,0.14803569668995656,-0.5694567741728175,3.95895741112925,-0.08889808473863031,0.8471185516552913,0.2657314452879552,-0.2081715578352066,0.33611163062394667,3.9163763942062166,0.6391237598897699,-0.017596227567052123,-0.1603956915349074,2.5105058405134244,1.145146616611409,0.5694744024903953,0.19517407509175846,1.9570211264778132,-0.06510924961463846,-0.40018942775227584,-0.83797308570648,-0.7889123757164783,0.3595328957429135,-0.04134201322447215,0.31267104849579785,0.17161498562321423,-1.2596499307860836,-0.32800834772899334,-0.49676620728557386,-0.2320932034861173,-0.40018942775227584,0.14803569668995656,-0.5452016332533733,-0.4484293059503235,1.1907552610982108,1.0537389733278402,0.31267104849579785,0.029831574171165644,-1.0849716204143893,-0.2081715578352066,0.3595328957429135,1.6435030564502273,-0.13654115282560736,-0.49676620728557386,2.134995856182529,0.10081598985120394,2.312151123677215,0.17161498562321423,0.8701429845725451,1.4178726825545127,0.24223217662498808,1.0766148888424223,0.3595328957429135,-0.13654115282560736,-1.3601684318707938,0.4530271695640074,-0.5937371293542618,-0.04134201322447215,-0.18427244054683523,-1.3349893470843226,1.145146616611409,-0.1603956915349074
| 3,067
|
Contractures of the joints of the upper limbs
| 9
| 66
| 2.299332
| 0.021486
|
Q9NR77,P37268,Q15392,Q99720,P23786,P35637,O75844,P42892,P98172
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
8,139,77,17,147,149,58,59,157
|
1855,1102,1799,1148,2395,1400,2952,826,1571,58,1863,898,461,1461,2183,936,1575,2599,2368,147,2443,1068,1876,149,139,1411,59,2846,325,281,1417,1364,1276,157,697,949,2934,2245,2416,993,1595,1478,3016,77,2762,1083,3027,1290,775,1291,1726,1044,1486,1607,677,17,386,2498,1006,2311,1136,8,2533,1053,203,660
|
-0.2081715578352066,0.12443607605412232,-0.18427244054683523,0.10081598985120394,-0.49676620728557386,-0.017596227567052123,-1.3601684318707938,0.28921102773708735,-0.08889808473863031,2.5764078869149727,-0.2081715578352066,0.24223217662498808,0.5927088870625801,-0.04134201322447215,-0.37610541469729714,0.21871309573559264,-0.08889808473863031,-0.6423742870091806,-0.47258553589199437,1.3952290840127508,-0.5209715091499124,0.14803569668995656,-0.2081715578352066,1.3952290840127508,1.4405014163205085,-0.017596227567052123,2.5544523677537962,-0.9858252312843699,0.8471185516552913,0.9391154562432038,-0.017596227567052123,0.006128253475181141,0.05351387697527753,1.304504542365476,0.38293496406007926,0.21871309573559264,-1.2596499307860836,-0.40018942775227584,-0.49676620728557386,0.19517407509175846,-0.08889808473863031,-0.04134201322447215,-1.975273747434785,2.0905801244850664,-0.83797308570648,0.14803569668995656,-2.1850086375330573,0.05351387697527753,0.33611163062394667,0.05351387697527753,-0.13654115282560736,0.17161498562321423,-0.04134201322447215,-0.08889808473863031,0.40631795439279017,4.2982861261730845,0.7317400515807754,-0.5452016332533733,0.19517407509175846,-0.4242973311338641,0.12443607605412232,5.4067425730737195,-0.5694567741728175,0.17161498562321423,1.145146616611409,0.4296819841917649
| 3,067
|
Response to toxic substance
| 6
| 48
| 2.28914
| 0.022071
|
P07099,Q15165,P08183,O95831,P27544,P06493
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,40,12,14,84,25
|
1903,1399,2004,1060,14,1510,2819,2567,2842,25,2,1461,403,12,859,2932,2597,2789,2057,1317,84,1874,2774,2804,1269,2142,98,941,258,2328,2652,339,340,3000,40,2714,491,2762,1545,1378,878,1179,1241,2617,1791,2785,419,1561
|
-0.2320932034861173,-0.017596227567052123,-0.28000473103222856,0.14803569668995656,4.6563469220776925,-0.06510924961463846,-0.9364275680017444,-0.618042899175275,-0.9858252312843699,3.95895741112925,7.100946539783739,-0.04134201322447215,0.6854672060130802,5.095325835237832,0.2657314452879552,-1.2596499307860836,-0.6423742870091806,-0.8871441784646263,-0.3039949440411763,0.029831574171165644,2.0238595222072155,-0.2081715578352066,-0.8625447160545955,-0.9117717140860812,0.05351387697527753,-0.35204511338992117,1.8005977335130876,0.21871309573559264,0.9850140031000338,-0.4484293059503235,-0.691114745586028,0.8010187077276009,0.8010187077276009,-1.7678418524139115,3.229806250235141,-0.7644228326298534,0.5694744024903953,-0.83797308570648,-0.06510924961463846,0.006128253475181141,0.2657314452879552,0.10081598985120394,0.0771753025605692,-0.6423742870091806,-0.1603956915349074,-0.8625447160545955,0.6854672060130802,-0.06510924961463846
| 3,067
|
Abnormality of femur morphology
| 8
| 65
| 2.279902
| 0.022614
|
O75718,Q9H173,O95831,Q32P28,Q96HY6,Q14739,O75844,P46100
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
6,168,14,48,51,182,58,61
|
1258,1102,1799,2904,1148,2952,2397,1205,1571,6,58,1755,14,898,1263,1458,1063,2473,2507,1110,2183,2907,936,2599,1214,1068,355,2191,61,2846,2100,2941,722,1117,1525,2240,182,1595,1171,48,2826,808,2894,1083,2679,1664,1781,1431,1486,51,1341,1731,168,2045,3001,1993,1899,1010,1996,2431,3008,1393,784,1197,203
|
0.05351387697527753,0.12443607605412232,-0.18427244054683523,-1.1846005429298558,0.10081598985120394,-1.3601684318707938,-0.49676620728557386,0.0771753025605692,-0.08889808473863031,5.592772581581793,2.5764078869149727,-0.1603956915349074,4.6563469220776925,0.24223217662498808,0.05351387697527753,-0.04134201322447215,0.14803569668995656,-0.5452016332533733,-0.5694567741728175,0.12443607605412232,-0.37610541469729714,-1.1846005429298558,0.21871309573559264,-0.6423742870091806,0.0771753025605692,0.14803569668995656,0.7779431050658644,-0.37610541469729714,2.5105058405134244,-0.9858252312843699,-0.32800834772899334,-1.2847304228470318,0.3595328957429135,0.12443607605412232,-0.06510924961463846,-0.40018942775227584,1.2135360793065495,-0.08889808473863031,0.10081598985120394,2.795323733143928,-0.9364275680017444,0.31267104849579785,-1.109832915775756,0.14803569668995656,-0.7155242386586748,-0.11270866851683332,-0.1603956915349074,-0.017596227567052123,-0.04134201322447215,2.7297697351237553,0.029831574171165644,-0.13654115282560736,1.2590511132682145,-0.28000473103222856,-1.7678418524139115,-0.25603753973957905,-0.2081715578352066,0.19517407509175846,-0.25603753973957905,-0.49676620728557386,-1.8712608865208158,0.006128253475181141,0.33611163062394667,0.10081598985120394,1.145146616611409
| 3,067
|
Abnormal femoral neck morphology
| 6
| 37
| 2.275415
| 0.022881
|
O75718,Q9H173,O95831,Q96HY6,O75844,P46100
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
6,168,14,51,58,61
|
1102,2904,2397,1205,1571,6,58,14,898,1458,2183,2907,2599,1214,1068,355,61,2846,2100,722,1525,2240,1595,1171,2826,1431,1486,51,1341,168,3001,1993,1899,1393,784,1197,203
|
0.12443607605412232,-1.1846005429298558,-0.49676620728557386,0.0771753025605692,-0.08889808473863031,5.592772581581793,2.5764078869149727,4.6563469220776925,0.24223217662498808,-0.04134201322447215,-0.37610541469729714,-1.1846005429298558,-0.6423742870091806,0.0771753025605692,0.14803569668995656,0.7779431050658644,2.5105058405134244,-0.9858252312843699,-0.32800834772899334,0.3595328957429135,-0.06510924961463846,-0.40018942775227584,-0.08889808473863031,0.10081598985120394,-0.9364275680017444,-0.017596227567052123,-0.04134201322447215,2.7297697351237553,0.029831574171165644,1.2590511132682145,-1.7678418524139115,-0.25603753973957905,-0.2081715578352066,0.006128253475181141,0.33611163062394667,0.10081598985120394,1.145146616611409
| 3,067
|
Thioredoxin, conserved site [IPR017937]
| 9
| 11
| 2.267103
| 0.023384
|
P30101,Q8NBS9,P07237,Q15084,Q9H3N1,O43396,Q8IXB1,O95881,P13667
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
310,329,256,207,420,121,222,309,279
|
121,309,256,279,310,207,222,329,497,2841,420
|
1.530869168826082,0.8701429845725451,0.9850140031000338,0.9391154562432038,0.8701429845725451,1.1223186256989308,1.0994747445642425,0.8471185516552913,0.5694744024903953,-0.9611119893223657,0.6854672060130802
| 3,067
|
Organic hydroxy compound transport
| 10
| 31
| 2.264626
| 0.023536
|
Q14728,P35610,Q86Y82,P53985,O15439,P28288,P30536,Q9H4L5,Q8WTV0,Q9UHB6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
68,102,71,91,170,205,85,287,27,127
|
291,170,1152,2276,1355,1067,2096,2058,205,85,102,91,2731,905,68,468,71,2211,27,2658,1487,2851,2661,2617,2309,2310,287,885,741,127,2950
|
0.9161413439901327,1.2363013365837792,0.10081598985120394,-0.4242973311338641,0.006128253475181141,0.14803569668995656,-0.32800834772899334,-0.3039949440411763,1.1223186256989308,2.0015932231890448,1.7333549222805171,1.9123959679548161,-0.7889123757164783,0.24223217662498808,2.2679375802329096,0.5927088870625801,2.179360380668593,-0.37610541469729714,3.8737579156642066,-0.691114745586028,-0.04134201322447215,-0.9858252312843699,-0.691114745586028,-0.6423742870091806,-0.4242973311338641,-0.4242973311338641,0.9391154562432038,0.2657314452879552,0.3595328957429135,1.5082991632477938,-1.3349893470843226
| 3,067
|
Alpha/Beta hydrolase fold [IPR029058]
| 8
| 26
| 2.241146
| 0.025017
|
P07099,P34913,Q4J6C6,Q9HB40,Q8NCC3,P42785,Q9NUJ1,Q9UMR5
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
2,98,39,103,42,18,92,94
|
2275,2,2753,2932,2279,98,3057,18,2193,2478,2575,39,2381,1603,1545,731,42,1894,2851,3056,119,103,92,1900,94,2866
|
-0.4242973311338641,7.100946539783739,-0.83797308570648,-1.2596499307860836,-0.4242973311338641,1.8005977335130876,-4.101822668364672,4.234837774349021,-0.37610541469729714,-0.5452016332533733,-0.618042899175275,3.273018749025682,-0.47258553589199437,-0.08889808473863031,-0.06510924961463846,0.3595328957429135,3.164908831693504,-0.2081715578352066,-0.9858252312843699,-3.9043965485654306,1.575965742470364,1.710912956736977,1.9123959679548161,-0.2081715578352066,1.8900633397760067,-1.0105675513507224
| 3,067
|
Meiotic cell cycle
| 6
| 49
| 2.239971
| 0.025093
|
Q9BTX1,Q92791,Q9UQ84,P53350,P24941,P46100
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
131,5,21,88,26,61
|
2226,2091,2698,2750,2319,1061,1402,1959,1404,754,26,2570,1514,2542,939,61,598,484,1071,88,2330,2198,2200,1706,724,2989,993,767,1172,2711,2337,451,1088,5,626,2522,2388,131,1731,1437,142,1555,458,1137,781,1620,21,821,1306
|
-0.40018942775227584,-0.32800834772899334,-0.7644228326298534,-0.83797308570648,-0.4484293059503235,0.14803569668995656,-0.017596227567052123,-0.25603753973957905,-0.017596227567052123,0.33611163062394667,3.9163763942062166,-0.618042899175275,-0.06510924961463846,-0.5937371293542618,0.21871309573559264,2.5105058405134244,0.4763536252951922,0.5694744024903953,0.14803569668995656,1.9570211264778132,-0.4484293059503235,-0.37610541469729714,-0.37610541469729714,-0.13654115282560736,0.3595328957429135,-1.613861950804346,0.19517407509175846,0.33611163062394667,0.10081598985120394,-0.7644228326298534,-0.4484293059503235,0.6159253041543369,0.14803569668995656,5.716460207824872,0.4530271695640074,-0.5694567741728175,-0.47258553589199437,1.4857145839161021,-0.13654115282560736,-0.017596227567052123,1.4405014163205085,-0.06510924961463846,0.6159253041543369,0.12443607605412232,0.33611163062394667,-0.08889808473863031,4.107699521261922,0.31267104849579785,0.05351387697527753
| 3,067
|
G2 m checkpoints
| 8
| 80
| 2.226901
| 0.025954
|
Q9Y3B8,P28074,P28070,Q9UQ84,P06493,P24941,P49721,Q99436
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
70,129,44,21,25,26,60,62
|
1056,1565,2903,1857,1952,1351,1454,1061,1862,897,1063,25,860,1867,754,2054,976,26,1577,2185,1466,1467,1873,1964,2570,2186,44,2998,129,832,1114,1578,1026,2284,1917,2445,2446,1815,2327,2448,1363,60,981,484,984,2290,2196,1365,694,2331,1528,1825,2019,1768,2332,1279,1368,1422,2152,1475,2107,2934,2156,1081,2336,1980,1663,417,1725,626,62,1841,634,2558,656,2831,1620,21,70,203
|
0.14803569668995656,-0.08889808473863031,-1.1846005429298558,-0.2081715578352066,-0.25603753973957905,0.006128253475181141,-0.04134201322447215,0.14803569668995656,-0.2081715578352066,0.24223217662498808,0.14803569668995656,3.95895741112925,0.2657314452879552,-0.2081715578352066,0.33611163062394667,-0.3039949440411763,0.19517407509175846,3.9163763942062166,-0.08889808473863031,-0.37610541469729714,-0.04134201322447215,-0.04134201322447215,-0.2081715578352066,-0.25603753973957905,-0.618042899175275,-0.37610541469729714,3.0999160722803394,-1.7678418524139115,1.4857145839161021,0.28921102773708735,0.12443607605412232,-0.08889808473863031,0.17161498562321423,-0.4242973311338641,-0.2320932034861173,-0.5209715091499124,-0.5209715091499124,-0.18427244054683523,-0.4484293059503235,-0.5209715091499124,0.006128253475181141,2.5544523677537962,0.19517407509175846,0.5694744024903953,0.19517407509175846,-0.4242973311338641,-0.37610541469729714,0.006128253475181141,0.38293496406007926,-0.4484293059503235,-0.06510924961463846,-0.18427244054683523,-0.28000473103222856,-0.1603956915349074,-0.4484293059503235,0.05351387697527753,0.006128253475181141,-0.017596227567052123,-0.35204511338992117,-0.04134201322447215,-0.32800834772899334,-1.2596499307860836,-0.35204511338992117,0.14803569668995656,-0.4484293059503235,-0.25603753973957905,-0.11270866851683332,0.6854672060130802,-0.13654115282560736,0.4530271695640074,2.4004302172902574,-0.18427244054683523,0.4530271695640074,-0.5937371293542618,0.4296819841917649,-0.9364275680017444,-0.08889808473863031,4.107699521261922,2.201523579504294,1.145146616611409
| 3,067
|
Abnormal diaphysis morphology
| 12
| 61
| 2.217613
| 0.026581
|
Q9NX62,Q9Y619,O75718,P07237,Q9NR77,P48651,Q13126,Q32P28,Q96HY6,Q9NSE4,Q14739,P46100
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
263,203,6,256,8,325,10,48,51,351,182,61
|
1855,1016,1799,2904,1148,1456,2397,1205,6,3054,1755,256,2401,2183,2956,2907,936,366,2598,2599,2366,1214,1068,1876,1917,2685,833,61,2846,325,1879,2941,722,1119,1592,1976,2731,10,949,182,1595,2654,2158,1598,48,1083,2679,1781,1486,51,2123,8,351,1899,263,1498,1255,784,2129,1197,203
|
-0.2081715578352066,0.17161498562321423,-0.18427244054683523,-1.1846005429298558,0.10081598985120394,-0.04134201322447215,-0.49676620728557386,0.0771753025605692,5.592772581581793,-3.4852807505811203,-0.1603956915349074,0.9850140031000338,-0.49676620728557386,-0.37610541469729714,-1.3853810437648244,-1.1846005429298558,0.21871309573559264,0.7548502524793712,-0.6423742870091806,-0.6423742870091806,-0.47258553589199437,0.0771753025605692,0.14803569668995656,-0.2081715578352066,-0.2320932034861173,-0.7399601945456966,0.28921102773708735,2.5105058405134244,-0.9858252312843699,0.8471185516552913,-0.2081715578352066,-1.2847304228470318,0.3595328957429135,0.12443607605412232,-0.08889808473863031,-0.25603753973957905,-0.7889123757164783,5.282383753260578,0.21871309573559264,1.2135360793065495,-0.08889808473863031,-0.691114745586028,-0.35204511338992117,-0.08889808473863031,2.795323733143928,0.14803569668995656,-0.7155242386586748,-0.1603956915349074,-0.04134201322447215,2.7297697351237553,-0.32800834772899334,5.4067425730737195,0.8010187077276009,-0.2081715578352066,0.9850140031000338,-0.04134201322447215,0.0771753025605692,0.33611163062394667,-0.32800834772899334,0.10081598985120394,1.145146616611409
| 3,067
|
Anion transmembrane transport
| 9
| 44
| 2.206506
| 0.027349
|
Q14728,Q9BQT8,Q8TDW0,P08183,O15439,P30825,P41440,P53985,Q9UHG3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
68,72,173,12,170,53,23,91,29
|
170,1260,1455,1956,3034,2092,2182,1460,12,689,1156,2404,324,53,23,2573,2480,2941,2237,91,1525,1474,837,2335,68,3031,489,2074,470,1667,173,520,72,712,2125,2634,2590,29,1252,2502,1850,203,1449,1564
|
1.2363013365837792,0.05351387697527753,-0.04134201322447215,-0.25603753973957905,-2.343740308741473,-0.32800834772899334,-0.37610541469729714,-0.04134201322447215,5.095325835237832,0.38293496406007926,0.10081598985120394,-0.49676620728557386,0.8471185516552913,2.6422040422429265,4.02275923887349,-0.618042899175275,-0.5452016332533733,-1.2847304228470318,-0.40018942775227584,1.9123959679548161,-0.06510924961463846,-0.04134201322447215,0.28921102773708735,-0.4484293059503235,2.2679375802329096,-2.2377862069557604,0.5694744024903953,-0.3039949440411763,0.5927088870625801,-0.11270866851683332,1.2363013365837792,0.546221743136157,2.179360380668593,0.38293496406007926,-0.32800834772899334,-0.6667314992911156,-0.618042899175275,3.702904303597902,0.0771753025605692,-0.5452016332533733,-0.18427244054683523,1.145146616611409,-0.017596227567052123,-0.06510924961463846
| 3,067
|
Protein serine kinase activity
| 7
| 51
| 2.197123
| 0.028012
|
Q96GD4,Q14004,P49840,P49841,P53350,P06493,P24941
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
65,38,11,46,88,25,26
|
255,363,2319,2670,2277,2007,25,2183,1698,366,2598,1872,2282,155,26,2756,1068,2685,1877,1818,11,46,722,88,2241,1976,1222,2414,1328,392,1594,2934,2335,2244,38,1713,426,994,1330,1602,2783,1781,65,1939,1676,2984,1488,2172,711,2765,965
|
0.9850140031000338,0.7548502524793712,-0.4484293059503235,-0.7155242386586748,-0.4242973311338641,-0.28000473103222856,3.95895741112925,-0.37610541469729714,-0.13654115282560736,0.7548502524793712,-0.6423742870091806,-0.2081715578352066,-0.4242973311338641,1.304504542365476,3.9163763942062166,-0.83797308570648,0.14803569668995656,-0.7399601945456966,-0.2081715578352066,-0.18427244054683523,5.157748552028619,2.9478894554497037,0.3595328957429135,1.9570211264778132,-0.40018942775227584,-0.25603753973957905,0.0771753025605692,-0.49676620728557386,0.029831574171165644,0.7086124029290911,-0.08889808473863031,-1.2596499307860836,-0.4484293059503235,-0.40018942775227584,3.273018749025682,-0.13654115282560736,0.6623043592342954,0.19517407509175846,0.029831574171165644,-0.08889808473863031,-0.8625447160545955,-0.1603956915349074,2.312151123677215,-0.2320932034861173,-0.11270866851683332,-1.588331377422339,-0.04134201322447215,-0.35204511338992117,0.38293496406007926,-0.83797308570648,0.21871309573559264
| 3,067
|
Mitochondrial transport
| 15
| 85
| 2.194894
| 0.028171
|
Q5JRX3,P55786,Q99595,P00846,Q9NS69,P06576,Q10713,P49840,O43772,O95831,P49841,Q8WWC4,P23786,P30536,O60830
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
262,35,4,36,67,293,228,11,13,14,46,305,147,85,28
|
928,1016,1507,2736,744,13,2720,28,1205,1807,2052,2137,1692,2322,2875,2834,14,718,36,1063,2182,293,2138,859,1812,1156,2282,147,1576,1358,2097,2877,85,2370,1361,1518,2573,2512,2513,11,46,2674,864,1920,35,2759,2822,3063,1974,228,1479,2071,2205,2550,262,1658,2422,874,774,2344,1724,2210,958,305,455,2081,1728,4,549,317,2588,1443,67,2126,609,2769,2590,387,1252,888,658,2534,1394,362,3002
|
0.21871309573559264,0.17161498562321423,-0.06510924961463846,-0.8134290501122715,0.33611163062394667,4.970267139748916,-0.7889123757164783,3.702904303597902,0.0771753025605692,-0.18427244054683523,-0.3039949440411763,-0.35204511338992117,-0.13654115282560736,-0.4484293059503235,-1.060140477409233,-0.9611119893223657,4.6563469220776925,0.3595328957429135,3.273018749025682,0.14803569668995656,-0.37610541469729714,0.9161413439901327,-0.35204511338992117,0.2657314452879552,-0.18427244054683523,0.10081598985120394,-0.4242973311338641,1.3952290840127508,-0.08889808473863031,0.006128253475181141,-0.32800834772899334,-1.060140477409233,2.0015932231890448,-0.47258553589199437,0.006128253475181141,-0.06510924961463846,-0.618042899175275,-0.5694567741728175,-0.5694567741728175,5.157748552028619,2.9478894554497037,-0.7155242386586748,0.2657314452879552,-0.2320932034861173,3.294609379601925,-0.83797308570648,-0.9364275680017444,-6.191987398232292,-0.25603753973957905,1.0766148888424223,-0.04134201322447215,-0.3039949440411763,-0.37610541469729714,-0.5937371293542618,0.9850140031000338,-0.11270866851683332,-0.49676620728557386,0.2657314452879552,0.33611163062394667,-0.4484293059503235,-0.13654115282560736,-0.37610541469729714,0.21871309573559264,0.8931505508985713,0.6159253041543369,-0.3039949440411763,-0.13654115282560736,6.167780078048627,0.522950800501484,0.8701429845725451,-0.618042899175275,-0.017596227567052123,2.290050562055856,-0.32800834772899334,0.4763536252951922,-0.83797308570648,-0.618042899175275,0.7317400515807754,0.0771753025605692,0.2657314452879552,0.4296819841917649,-0.5694567741728175,0.006128253475181141,0.7779431050658644,-1.793639886085142
| 3,067
|
Microbody
| 17
| 57
| 2.188694
| 0.028619
|
P56589,P34913,P08670,Q9BY49,Q9NR77,Q15067,Q9Y4I1,O75381,P33121,O14975,P28288,Q15126,Q8N4Q0,Q9GZY8,P48735,P39210,O15254
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
326,98,257,201,8,140,175,171,148,300,205,246,24,317,90,214,30
|
1258,1856,743,300,1567,30,1260,1689,171,2770,931,1754,257,2915,1814,1756,2058,205,2187,2804,148,98,2014,2685,214,1580,90,2649,1646,326,3064,2779,140,246,2339,1173,648,1931,2028,24,1780,958,494,1241,1606,814,361,439,201,317,714,8,2086,2221,1561,175,1198
|
0.05351387697527753,-0.2081715578352066,0.33611163062394667,0.8931505508985713,-0.08889808473863031,3.63867524824419,0.05351387697527753,-0.13654115282560736,1.2363013365837792,-0.8625447160545955,0.21871309573559264,-0.1603956915349074,0.9850140031000338,-1.2095852996870387,-0.18427244054683523,-0.1603956915349074,-0.3039949440411763,1.1223186256989308,-0.37610541469729714,-0.9117717140860812,1.3952290840127508,1.8005977335130876,-0.28000473103222856,-0.7399601945456966,1.0994747445642425,-0.08889808473863031,1.9347152099627174,-0.691114745586028,-0.11270866851683332,0.8471185516552913,-7.272381138561336,-0.8625447160545955,1.4405014163205085,1.030846911961832,-0.4484293059503235,0.10081598985120394,0.4296819841917649,-0.2320932034861173,-0.28000473103222856,3.980233949280333,-0.1603956915349074,0.21871309573559264,0.5694744024903953,0.0771753025605692,-0.08889808473863031,0.31267104849579785,0.7779431050658644,0.6391237598897699,1.145146616611409,0.8701429845725451,0.38293496406007926,5.4067425730737195,-0.3039949440411763,-0.37610541469729714,-0.06510924961463846,1.2363013365837792,0.10081598985120394
| 3,067
|
Serine/threonine-protein kinase
| 12
| 50
| 2.173312
| 0.029757
|
Q96GD4,Q14004,O14936,P49840,Q13464,P49841,P17252,O14976,P53350,P06493,P24941,P21127
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
65,38,255,11,392,46,366,363,88,25,26,155
|
255,363,2319,2670,2277,2007,25,2183,1698,366,2598,1872,2282,155,26,2756,1068,2685,1877,1818,11,46,722,88,2241,1976,1222,2414,1328,392,1594,2934,2335,2244,38,1713,426,994,1330,2783,1781,65,1939,1676,2984,1488,2172,711,2765,965
|
0.9850140031000338,0.7548502524793712,-0.4484293059503235,-0.7155242386586748,-0.4242973311338641,-0.28000473103222856,3.95895741112925,-0.37610541469729714,-0.13654115282560736,0.7548502524793712,-0.6423742870091806,-0.2081715578352066,-0.4242973311338641,1.304504542365476,3.9163763942062166,-0.83797308570648,0.14803569668995656,-0.7399601945456966,-0.2081715578352066,-0.18427244054683523,5.157748552028619,2.9478894554497037,0.3595328957429135,1.9570211264778132,-0.40018942775227584,-0.25603753973957905,0.0771753025605692,-0.49676620728557386,0.029831574171165644,0.7086124029290911,-0.08889808473863031,-1.2596499307860836,-0.4484293059503235,-0.40018942775227584,3.273018749025682,-0.13654115282560736,0.6623043592342954,0.19517407509175846,0.029831574171165644,-0.8625447160545955,-0.1603956915349074,2.312151123677215,-0.2320932034861173,-0.11270866851683332,-1.588331377422339,-0.04134201322447215,-0.35204511338992117,0.38293496406007926,-0.83797308570648,0.21871309573559264
| 3,067
|
Cell cycle
| 6
| 45
| 2.171697
| 0.029878
|
Q9Y619,Q9Y3B8,P49841,P53350,P06493,P24941
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
203,70,46,88,25,26
|
2698,1454,2750,1063,2507,25,1698,1464,860,26,1577,1964,1760,832,1114,1578,1026,981,46,88,1528,1768,1368,2150,2241,1422,1282,1535,2934,1711,2156,993,623,241,1838,2123,656,1740,636,782,1846,2533,821,70,203
|
-0.7644228326298534,-0.04134201322447215,-0.83797308570648,0.14803569668995656,-0.5694567741728175,3.95895741112925,-0.13654115282560736,-0.04134201322447215,0.2657314452879552,3.9163763942062166,-0.08889808473863031,-0.25603753973957905,-0.1603956915349074,0.28921102773708735,0.12443607605412232,-0.08889808473863031,0.17161498562321423,0.19517407509175846,2.9478894554497037,1.9570211264778132,-0.06510924961463846,-0.1603956915349074,0.006128253475181141,-0.35204511338992117,-0.40018942775227584,-0.017596227567052123,0.05351387697527753,-0.06510924961463846,-1.2596499307860836,-0.13654115282560736,-0.35204511338992117,0.19517407509175846,0.4530271695640074,1.0537389733278402,-0.18427244054683523,-0.32800834772899334,0.4296819841917649,-0.13654115282560736,0.4530271695640074,0.33611163062394667,-0.18427244054683523,-0.5694567741728175,0.31267104849579785,2.201523579504294,1.145146616611409
| 3,067
|
Atpase coupled transmembrane transporter activity
| 6
| 21
| 2.166749
| 0.030254
|
P06576,P08183,Q9Y5K8,O15439,P28288,P36543
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
293,12,373,170,205,311
|
170,748,1634,1155,293,12,792,1065,1757,1913,205,941,311,2234,2941,1527,947,399,1443,1949,373
|
1.2363013365837792,0.33611163062394667,-0.11270866851683332,0.10081598985120394,0.9161413439901327,5.095325835237832,0.31267104849579785,0.14803569668995656,-0.1603956915349074,-0.2320932034861173,1.1223186256989308,0.21871309573559264,0.8701429845725451,-0.40018942775227584,-1.2847304228470318,-0.06510924961463846,0.21871309573559264,0.7086124029290911,-0.017596227567052123,-0.2320932034861173,0.7548502524793712
| 3,067
|
Regulation of cell cycle g2 m phase transition
| 6
| 32
| 2.165444
| 0.030354
|
Q96GD4,Q9Y619,P53350,P06493,P24941,Q68E01
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,203,88,25,26,188
|
2750,747,1061,1152,1627,1063,25,1572,1698,860,2702,26,198,484,1417,88,2108,2416,188,808,1725,2424,65,1046,316,1788,1381,634,2558,1496,2950,203
|
-0.83797308570648,0.33611163062394667,0.14803569668995656,0.10081598985120394,-0.11270866851683332,0.14803569668995656,3.95895741112925,-0.08889808473863031,-0.13654115282560736,0.2657314452879552,-0.7644228326298534,3.9163763942062166,1.145146616611409,0.5694744024903953,-0.017596227567052123,1.9570211264778132,-0.32800834772899334,-0.49676620728557386,1.1907552610982108,0.31267104849579785,-0.13654115282560736,-0.49676620728557386,2.312151123677215,0.17161498562321423,0.8701429845725451,-0.1603956915349074,0.006128253475181141,0.4530271695640074,-0.5937371293542618,-0.04134201322447215,-1.3349893470843226,1.145146616611409
| 3,067
|
Icosanoid metabolic process
| 6
| 18
| 2.153667
| 0.031266
|
P07099,Q15067,Q8N8N7,P14174,Q8N4Q0,Q9H7Z7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,140,22,55,24,63
|
1903,1354,2,365,55,2364,3041,150,140,2967,731,24,22,2658,1791,3056,63,1051
|
-0.2320932034861173,0.006128253475181141,7.100946539783739,0.7548502524793712,2.5983516406440144,-0.47258553589199437,-2.557194161657113,1.3952290840127508,1.4405014163205085,-1.4612234946070592,0.3595328957429135,3.980233949280333,4.044008051312098,-0.691114745586028,-0.1603956915349074,-3.9043965485654306,2.356315196972746,0.17161498562321423
| 3,067
|
Receptor
| 6
| 27
| 2.138478
| 0.032478
|
Q9NR77,Q567V2,O75381,A6NIH7,Q8WTV0,P39210
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
8,9,171,169,27,214
|
169,1259,2469,171,1907,2622,1460,2843,756,214,666,2154,1283,1078,2825,9,27,1089,2746,882,2962,1844,818,8,2800,2266,319
|
1.2363013365837792,0.05351387697527753,-0.5452016332533733,1.2363013365837792,-0.2320932034861173,-0.6667314992911156,-0.04134201322447215,-0.9858252312843699,0.33611163062394667,1.0994747445642425,0.40631795439279017,-0.35204511338992117,0.05351387697527753,0.14803569668995656,-0.9364275680017444,5.303129290746076,3.8737579156642066,0.14803569668995656,-0.8134290501122715,0.2657314452879552,-1.410627524712207,-0.18427244054683523,0.31267104849579785,5.4067425730737195,-0.8871441784646263,-0.40018942775227584,0.8701429845725451
| 3,067
|
Toe walking
| 6
| 21
| 2.135649
| 0.032708
|
Q8TD16,O95831,Q99720,P35637,Q9BTV4,P50402
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
330,14,17,149,386,281
|
1801,14,898,461,1110,149,795,281,2237,1364,2145,1821,1592,2416,2783,330,775,17,386,1996,660
|
-0.18427244054683523,4.6563469220776925,0.24223217662498808,0.5927088870625801,0.12443607605412232,1.3952290840127508,0.31267104849579785,0.9391154562432038,-0.40018942775227584,0.006128253475181141,-0.35204511338992117,-0.18427244054683523,-0.08889808473863031,-0.49676620728557386,-0.8625447160545955,0.8471185516552913,0.33611163062394667,4.2982861261730845,0.7317400515807754,-0.25603753973957905,0.4296819841917649
| 3,067
|
Disproportionate short limb short stature
| 6
| 17
| 2.125831
| 0.033517
|
Q14696,O75718,Q15392,Q32P28,Q14739,Q9UBM7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
380,6,77,48,182,289
|
1258,1567,2397,6,2538,2600,1877,2100,446,380,182,77,48,2762,1083,2387,289
|
0.05351387697527753,-0.08889808473863031,-0.49676620728557386,5.592772581581793,-0.5937371293542618,-0.6423742870091806,-0.2081715578352066,-0.32800834772899334,0.6159253041543369,0.7317400515807754,1.2135360793065495,2.0905801244850664,2.795323733143928,-0.83797308570648,0.14803569668995656,-0.47258553589199437,0.9391154562432038
| 3,067
|
Cell cycle
| 6
| 47
| 2.117516
| 0.034216
|
Q9Y619,Q9Y3B8,P49841,P53350,P06493,P24941
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
203,70,46,88,25,26
|
2698,1454,2750,2319,1063,2507,25,1698,1464,860,26,1577,1964,1760,832,1114,1578,1026,981,46,88,1528,1768,1368,2150,2241,1422,1282,1035,1535,2934,1711,2156,993,623,241,1838,2123,656,1740,636,782,1846,2533,821,70,203
|
-0.7644228326298534,-0.04134201322447215,-0.83797308570648,-0.4484293059503235,0.14803569668995656,-0.5694567741728175,3.95895741112925,-0.13654115282560736,-0.04134201322447215,0.2657314452879552,3.9163763942062166,-0.08889808473863031,-0.25603753973957905,-0.1603956915349074,0.28921102773708735,0.12443607605412232,-0.08889808473863031,0.17161498562321423,0.19517407509175846,2.9478894554497037,1.9570211264778132,-0.06510924961463846,-0.1603956915349074,0.006128253475181141,-0.35204511338992117,-0.40018942775227584,-0.017596227567052123,0.05351387697527753,0.17161498562321423,-0.06510924961463846,-1.2596499307860836,-0.13654115282560736,-0.35204511338992117,0.19517407509175846,0.4530271695640074,1.0537389733278402,-0.18427244054683523,-0.32800834772899334,0.4296819841917649,-0.13654115282560736,0.4530271695640074,0.33611163062394667,-0.18427244054683523,-0.5694567741728175,0.31267104849579785,2.201523579504294,1.145146616611409
| 3,067
|
Fatty acid metabolism
| 17
| 58
| 2.095002
| 0.036171
|
P34913,Q9BY49,Q15165,Q8IVS2,Q15067,O43772,P23786,P33121,O95864,Q8N8N7,Q14914,O14975,Q9UMR5,P09960,Q9H7Z7,O15254,P42126
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
98,201,40,294,140,13,147,148,301,22,150,300,94,365,63,30,280
|
2669,3049,743,300,30,13,1260,1689,2770,1754,301,2978,2723,2915,365,1513,3041,1266,1406,2058,147,2444,148,98,795,280,1518,2478,982,2674,2575,2649,1646,2237,2514,1821,3005,150,140,40,2967,394,1717,1230,2339,1931,294,2031,22,201,63,1734,1011,1012,2221,94,1797,660
|
-0.7155242386586748,-2.718584481499948,0.33611163062394667,0.8931505508985713,3.63867524824419,4.970267139748916,0.05351387697527753,-0.13654115282560736,-0.8625447160545955,-0.1603956915349074,0.8931505508985713,-1.5628376619481128,-0.7889123757164783,-1.2095852996870387,0.7548502524793712,-0.06510924961463846,-2.557194161657113,0.05351387697527753,-0.017596227567052123,-0.3039949440411763,1.3952290840127508,-0.5209715091499124,1.3952290840127508,1.8005977335130876,0.31267104849579785,0.9391154562432038,-0.06510924961463846,-0.5452016332533733,0.19517407509175846,-0.7155242386586748,-0.618042899175275,-0.691114745586028,-0.11270866851683332,-0.40018942775227584,-0.5694567741728175,-0.18427244054683523,-1.8194759423343025,1.3952290840127508,1.4405014163205085,3.229806250235141,-1.4612234946070592,0.7086124029290911,-0.13654115282560736,0.0771753025605692,-0.4484293059503235,-0.2320932034861173,0.9161413439901327,-0.28000473103222856,4.044008051312098,1.145146616611409,2.356315196972746,-0.13654115282560736,0.19517407509175846,0.19517407509175846,-0.37610541469729714,1.8900633397760067,-0.1603956915349074,0.4296819841917649
| 3,067
|
Cholesterol binding
| 6
| 13
| 2.092202
| 0.03642
|
P35610,P21796,O15118,P08133,P30536,Q9H4L5
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
102,324,291,243,85,287
|
291,828,1863,423,243,324,2058,85,102,2573,1283,2310,287
|
0.9161413439901327,0.28921102773708735,-0.2081715578352066,0.6623043592342954,1.030846911961832,0.8471185516552913,-0.3039949440411763,2.0015932231890448,1.7333549222805171,-0.618042899175275,0.05351387697527753,-0.4242973311338641,0.9391154562432038
| 3,067
|
Protein disulfide isomerase activity
| 7
| 9
| 2.062471
| 0.039163
|
P30101,Q96JJ7,Q8NBS9,P13667,P07237,Q15084,Q6ZRP7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
310,497,329,279,256,207,577
|
256,279,642,310,207,577,329,497,1895
|
0.9850140031000338,0.9391154562432038,0.4296819841917649,0.8701429845725451,1.1223186256989308,0.4996614648715897,0.8471185516552913,0.5694744024903953,-0.2081715578352066
| 3,067
|
Dolichocephaly
| 7
| 25
| 2.053622
| 0.040012
|
P61978,P56589,Q4J6C6,Q03164,O75381,Q9H3P2,P46100
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
215,326,39,446,171,191,61
|
171,1809,531,897,2597,1757,2443,1580,61,2100,1646,326,215,1592,446,1538,39,1891,1044,1674,1731,191,1010,2533,1198
|
1.2363013365837792,-0.18427244054683523,0.522950800501484,0.24223217662498808,-0.6423742870091806,-0.1603956915349074,-0.5209715091499124,-0.08889808473863031,2.5105058405134244,-0.32800834772899334,-0.11270866851683332,0.8471185516552913,1.0994747445642425,-0.08889808473863031,0.6159253041543369,-0.06510924961463846,3.273018749025682,-0.2081715578352066,0.17161498562321423,-0.11270866851683332,-0.13654115282560736,1.1907552610982108,0.19517407509175846,-0.5694567741728175,0.10081598985120394
| 3,067
|
Bilateral sensorineural hearing impairment
| 7
| 26
| 2.046876
| 0.04067
|
Q13217,P03915,Q15067,P38159,Q96GW9,Q9NSE4,P35637
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
193,100,140,109,306,351,149
|
1801,2566,480,100,1110,1575,1267,2509,355,149,109,2104,1525,2145,1592,1708,193,949,140,1721,772,306,961,351,1996,2222
|
-0.18427244054683523,-0.618042899175275,0.5694744024903953,1.7781972459390094,0.12443607605412232,-0.08889808473863031,0.05351387697527753,-0.5694567741728175,0.7779431050658644,1.3952290840127508,1.6435030564502273,-0.32800834772899334,-0.06510924961463846,-0.35204511338992117,-0.08889808473863031,-0.13654115282560736,1.1679588008379829,0.21871309573559264,1.4405014163205085,-0.13654115282560736,0.33611163062394667,0.8931505508985713,0.21871309573559264,0.8010187077276009,-0.25603753973957905,-0.37610541469729714
| 3,067
|
Peptide binding
| 12
| 72
| 2.043149
| 0.041038
|
Q92973,P55786,Q9Y584,P42892,O14773,P04439,Q15392,Q6P179,Q9NQX7,Q14978,Q8WTV0,Q9H7Z7
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
359,35,362,59,290,321,77,413,87,152,27,63
|
443,1017,1201,1566,2273,290,639,1749,894,1751,1692,1865,321,2475,2139,2231,1463,1756,2057,2600,1514,1874,2097,1761,1516,979,2544,1580,59,1519,1520,759,1162,985,1524,1031,35,644,2240,2608,2147,2149,947,905,803,2063,1978,1710,1714,152,77,413,2116,27,359,1338,2657,2348,1791,1097,679,680,63,1612,87,2558,1140,2591,1497,924,891,362
|
0.6159253041543369,0.17161498562321423,0.0771753025605692,-0.08889808473863031,-0.4242973311338641,0.9161413439901327,0.4296819841917649,-0.1603956915349074,0.24223217662498808,-0.1603956915349074,-0.13654115282560736,-0.2081715578352066,0.8471185516552913,-0.5452016332533733,-0.35204511338992117,-0.40018942775227584,-0.04134201322447215,-0.1603956915349074,-0.3039949440411763,-0.6423742870091806,-0.06510924961463846,-0.2081715578352066,-0.32800834772899334,-0.1603956915349074,-0.06510924961463846,0.19517407509175846,-0.5937371293542618,-0.08889808473863031,2.5544523677537962,-0.06510924961463846,-0.06510924961463846,0.33611163062394667,0.10081598985120394,0.19517407509175846,-0.06510924961463846,0.17161498562321423,3.294609379601925,0.4296819841917649,-0.40018942775227584,-0.6423742870091806,-0.35204511338992117,-0.35204511338992117,0.21871309573559264,0.24223217662498808,0.31267104849579785,-0.3039949440411763,-0.25603753973957905,-0.13654115282560736,-0.13654115282560736,1.3272083516406563,2.0905801244850664,0.6854672060130802,-0.32800834772899334,3.8737579156642066,0.7779431050658644,0.029831574171165644,-0.691114745586028,-0.4484293059503235,-0.1603956915349074,0.14803569668995656,0.40631795439279017,0.40631795439279017,2.356315196972746,-0.08889808473863031,1.979313777666358,-0.5937371293542618,0.12443607605412232,-0.618042899175275,-0.04134201322447215,0.24223217662498808,0.2657314452879552,0.7779431050658644
| 3,067
|
Lipid homeostasis
| 6
| 21
| 2.034312
| 0.04192
|
P34913,P35610,O15260,Q8WTV0,O15254,Q9UHB6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
98,102,57,27,30,127
|
1103,291,30,57,2276,2891,2012,98,102,3005,140,468,2968,27,2658,2500,1944,127,657,2050,400
|
0.12443607605412232,0.9161413439901327,3.63867524824419,2.5764078869149727,-0.4242973311338641,-1.109832915775756,-0.28000473103222856,1.8005977335130876,1.7333549222805171,-1.8194759423343025,1.4405014163205085,0.5927088870625801,-1.4612234946070592,3.8737579156642066,-0.691114745586028,-0.5452016332533733,-0.2320932034861173,1.5082991632477938,0.4296819841917649,-0.28000473103222856,0.7086124029290911
| 3,067
|
Cell surface
| 19
| 77
| 2.03272
| 0.042081
|
P07237,Q9HDC9,P08183,P41440,Q8WTV0,P13667,P06576,Q13740,O15439,Q9UNN8,P14174,P42892,P30101,Q13685,P00813,P04439,P09525,Q8IWT6,Q9UII2
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
256,276,12,23,27,279,293,425,170,52,55,59,310,448,196,321,204,470,387
|
638,2227,170,1688,2913,829,1632,2819,196,1865,1960,1354,321,1460,293,2771,256,1355,12,689,2475,2402,204,1463,1812,1313,2539,2843,279,55,1756,2755,2646,1358,2141,1514,642,310,1516,1318,23,59,2478,2480,2707,644,1533,904,991,2515,1223,1168,2202,1710,992,2154,448,425,1078,670,2074,673,470,2033,27,3053,1242,497,1990,1790,1895,276,852,387,52,1744,2788
|
0.4296819841917649,-0.40018942775227584,1.2363013365837792,-0.13654115282560736,-1.2095852996870387,0.28921102773708735,-0.11270866851683332,-0.9364275680017444,1.145146616611409,-0.2081715578352066,-0.25603753973957905,0.006128253475181141,0.8471185516552913,-0.04134201322447215,0.9161413439901327,-0.8625447160545955,0.9850140031000338,0.006128253475181141,5.095325835237832,0.38293496406007926,-0.5452016332533733,-0.49676620728557386,1.1223186256989308,-0.04134201322447215,-0.18427244054683523,0.029831574171165644,-0.5937371293542618,-0.9858252312843699,0.9391154562432038,2.5983516406440144,-0.1603956915349074,-0.83797308570648,-0.691114745586028,0.006128253475181141,-0.35204511338992117,-0.06510924961463846,0.4296819841917649,0.8701429845725451,-0.06510924961463846,0.029831574171165644,4.02275923887349,2.5544523677537962,-0.5452016332533733,-0.5452016332533733,-0.7644228326298534,0.4296819841917649,-0.06510924961463846,0.24223217662498808,0.19517407509175846,-0.5694567741728175,0.0771753025605692,0.10081598985120394,-0.37610541469729714,-0.13654115282560736,0.19517407509175846,-0.35204511338992117,0.6159253041543369,0.6623043592342954,0.14803569668995656,0.40631795439279017,-0.3039949440411763,0.40631795439279017,0.5927088870625801,-0.28000473103222856,3.8737579156642066,-3.402128987736986,0.0771753025605692,0.5694744024903953,-0.25603753973957905,-0.1603956915349074,-0.2081715578352066,0.9620729791073839,0.28921102773708735,0.7317400515807754,2.6641127844353147,-0.13654115282560736,-0.8625447160545955
| 3,067
|
Abnormal circulating bilirubin concentration
| 6
| 26
| 2.027507
| 0.042611
|
P36551,P23786,P28288,Q14739,P41440,P55263
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
258,147,205,182,23,56
|
255,2819,2536,2324,2772,532,1403,2508,1265,2055,147,205,258,1580,23,2757,56,1592,1073,182,2164,1553,2354,1390,1252,2269
|
0.9850140031000338,-0.9364275680017444,-0.5937371293542618,-0.4484293059503235,-0.8625447160545955,0.522950800501484,-0.017596227567052123,-0.5694567741728175,0.05351387697527753,-0.3039949440411763,1.3952290840127508,1.1223186256989308,0.9850140031000338,-0.08889808473863031,4.02275923887349,-0.83797308570648,2.5983516406440144,-0.08889808473863031,0.14803569668995656,1.2135360793065495,-0.35204511338992117,-0.06510924961463846,-0.4484293059503235,0.006128253475181141,0.0771753025605692,-0.40018942775227584
| 3,067
|
Endopeptidase activity
| 15
| 55
| 2.02508
| 0.042859
|
Q5JRX3,Q9Y4W6,Q96RU2,P28074,Q4J6C6,Q10713,O14773,P22695,P28070,Q16740,O75844,Q96K76,P42892,P49721,Q99436
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
262,298,233,129,39,228,290,197,44,115,58,316,59,60,62
|
290,2902,1688,1807,58,2596,2279,1756,2755,976,197,1873,44,2998,129,2060,310,833,59,2626,2193,1363,60,1523,1819,3030,2707,1365,1883,228,2414,3000,1329,115,39,262,2859,413,997,2033,733,2632,2493,1239,316,233,1184,62,549,2458,679,1140,609,890,298
|
0.9161413439901327,-1.1596470893841613,-0.13654115282560736,-0.18427244054683523,2.5764078869149727,-0.6423742870091806,-0.4242973311338641,-0.1603956915349074,-0.83797308570648,0.19517407509175846,1.145146616611409,-0.2081715578352066,3.0999160722803394,-1.7678418524139115,1.4857145839161021,-0.3039949440411763,0.8701429845725451,0.28921102773708735,2.5544523677537962,-0.6667314992911156,-0.37610541469729714,0.006128253475181141,2.5544523677537962,-0.06510924961463846,-0.18427244054683523,-2.2377862069557604,-0.7644228326298534,0.006128253475181141,-0.2081715578352066,1.0766148888424223,-0.49676620728557386,-1.7678418524139115,0.029831574171165644,1.5984924508056337,3.273018749025682,0.9850140031000338,-1.0105675513507224,0.6854672060130802,0.19517407509175846,-0.28000473103222856,0.3595328957429135,-0.6667314992911156,-0.5452016332533733,0.0771753025605692,0.8701429845725451,1.0766148888424223,0.10081598985120394,2.4004302172902574,0.522950800501484,-0.5209715091499124,0.40631795439279017,0.12443607605412232,0.4763536252951922,0.2657314452879552,0.9161413439901327
| 3,067
|
Serine hydrolase activity
| 6
| 17
| 2.014854
| 0.04392
|
Q5JRX3,Q9HB40,Q4J6C6,P42785,Q16740,Q9H3G5
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
262,103,39,18,115,119
|
290,2751,2753,2279,2060,833,18,2193,1031,3030,1883,115,39,262,1603,119,103
|
0.9161413439901327,-0.83797308570648,-0.83797308570648,-0.4242973311338641,-0.3039949440411763,0.28921102773708735,4.234837774349021,-0.37610541469729714,0.17161498562321423,-2.2377862069557604,-0.2081715578352066,1.5984924508056337,3.273018749025682,0.9850140031000338,-0.08889808473863031,1.575965742470364,1.710912956736977
| 3,067
|
Aging
| 7
| 67
| 2.00989
| 0.044443
|
Q96GD4,P00846,P14174,P06493,P24941,P46100,O75844
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,36,55,25,26,61,58
|
2467,2132,2905,2595,58,1752,751,36,898,1960,1263,2567,1063,2842,664,2094,25,1572,859,55,1756,754,1640,1575,1065,26,1358,1360,1514,2572,1158,85,1270,3061,2982,1764,61,834,1071,3030,1525,2577,251,1975,1976,1222,803,2243,1710,2934,1078,646,2490,2631,2492,729,1127,1177,2658,496,65,2660,2119,2387,1381,555,1390
|
-0.5452016332533733,-0.35204511338992117,-1.1846005429298558,-0.6423742870091806,2.5764078869149727,-0.1603956915349074,0.33611163062394667,3.273018749025682,0.24223217662498808,-0.25603753973957905,0.05351387697527753,-0.618042899175275,0.14803569668995656,-0.9858252312843699,0.40631795439279017,-0.32800834772899334,3.95895741112925,-0.08889808473863031,0.2657314452879552,2.5983516406440144,-0.1603956915349074,0.33611163062394667,-0.11270866851683332,-0.08889808473863031,0.14803569668995656,3.9163763942062166,0.006128253475181141,0.006128253475181141,-0.06510924961463846,-0.618042899175275,0.10081598985120394,2.0015932231890448,0.05351387697527753,-4.585875393219534,-1.588331377422339,-0.1603956915349074,2.5105058405134244,0.28921102773708735,0.14803569668995656,-2.2377862069557604,-0.06510924961463846,-0.618042899175275,1.0079386178201262,-0.25603753973957905,-0.25603753973957905,0.0771753025605692,0.31267104849579785,-0.40018942775227584,-0.13654115282560736,-1.2596499307860836,0.14803569668995656,0.4296819841917649,-0.5452016332533733,-0.6667314992911156,-0.5452016332533733,0.3595328957429135,0.12443607605412232,0.10081598985120394,-0.691114745586028,0.5694744024903953,2.312151123677215,-0.691114745586028,-0.32800834772899334,-0.47258553589199437,0.006128253475181141,0.522950800501484,0.006128253475181141
| 3,067
|
Cutaneous photosensitivity
| 7
| 23
| 1.991598
| 0.046415
|
P50336,Q06136,P36551,P22830,P37268,Q9UBM7,Q15126
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
64,34,258,76,139,289,246
|
1061,1206,2867,1209,1464,2956,1157,1575,1267,76,2407,2509,355,258,139,64,2760,34,724,1283,246,289,2735
|
0.14803569668995656,0.0771753025605692,-1.0353392113150601,0.0771753025605692,-0.04134201322447215,-1.3853810437648244,0.10081598985120394,-0.08889808473863031,0.05351387697527753,2.1127944193228467,-0.49676620728557386,-0.5694567741728175,0.7779431050658644,0.9850140031000338,1.4405014163205085,2.312151123677215,-0.83797308570648,3.359319250021542,0.3595328957429135,0.05351387697527753,1.030846911961832,0.9391154562432038,-0.7889123757164783
| 3,067
|
Unsaturated fatty acid metabolic process
| 6
| 21
| 1.987025
| 0.04692
|
P07099,Q15067,Q8N8N7,P14174,Q8N4Q0,Q9H7Z7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,140,22,55,24,63
|
743,2833,301,1354,2,2915,55,2364,3041,2058,1874,150,140,2967,731,24,22,2658,3056,63,1051
|
0.33611163062394667,-0.9611119893223657,0.8931505508985713,0.006128253475181141,7.100946539783739,-1.2095852996870387,2.5983516406440144,-0.47258553589199437,-2.557194161657113,-0.3039949440411763,-0.2081715578352066,1.3952290840127508,1.4405014163205085,-1.4612234946070592,0.3595328957429135,3.980233949280333,4.044008051312098,-0.691114745586028,-3.9043965485654306,2.356315196972746,0.17161498562321423
| 3,067
|
Cell cycle g2 m phase transition
| 9
| 43
| 1.983367
| 0.047326
|
Q96GD4,Q9Y619,P49454,P08183,O43823,P53350,P06493,P24941,Q68E01
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,203,198,12,266,88,25,26,188
|
2226,562,266,2750,747,1061,1152,1627,1063,25,1572,12,3050,1698,860,2702,26,2194,198,484,1584,1417,88,1423,1535,2108,2416,188,808,1725,2424,65,1046,316,1788,1381,634,2558,1496,1901,2950,2866,203
|
-0.40018942775227584,0.4996614648715897,0.9620729791073839,-0.83797308570648,0.33611163062394667,0.14803569668995656,0.10081598985120394,-0.11270866851683332,0.14803569668995656,3.95895741112925,-0.08889808473863031,5.095325835237832,-2.8267739045918234,-0.13654115282560736,0.2657314452879552,-0.7644228326298534,3.9163763942062166,-0.37610541469729714,1.145146616611409,0.5694744024903953,-0.08889808473863031,-0.017596227567052123,1.9570211264778132,-0.017596227567052123,-0.06510924961463846,-0.32800834772899334,-0.49676620728557386,1.1907552610982108,0.31267104849579785,-0.13654115282560736,-0.49676620728557386,2.312151123677215,0.17161498562321423,0.8701429845725451,-0.1603956915349074,0.006128253475181141,0.4530271695640074,-0.5937371293542618,-0.04134201322447215,-0.2081715578352066,-1.3349893470843226,-1.0105675513507224,1.145146616611409
| 3,067
|
Cholesterol biosynthesis
| 6
| 15
| 1.980823
| 0.047611
|
Q15392,P37268,Q16850,Q9BWD1,Q14739,Q15126
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
77,139,50,114,182,246
|
1157,139,943,2999,2710,2779,1122,182,246,77,1657,538,50,114,289
|
0.10081598985120394,1.4405014163205085,0.21871309573559264,-1.7678418524139115,-0.7644228326298534,-0.8625447160545955,0.12443607605412232,1.2135360793065495,1.030846911961832,2.0905801244850664,-0.11270866851683332,0.522950800501484,2.7297697351237553,1.6210048659429874,0.9391154562432038
| 3,067
|
Iron ion binding
| 7
| 20
| 1.975808
| 0.048177
|
P22830,Q9BU89,Q32P28,Q6UW02,Q16850,O15460,P13674
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
76,47,48,303,50,176,244
|
1799,176,2952,375,244,76,1514,1112,1471,697,538,50,48,303,2214,47,2931,2899,2124,1500
|
-0.18427244054683523,1.2135360793065495,-1.3601684318707938,0.7317400515807754,1.030846911961832,2.1127944193228467,-0.06510924961463846,0.12443607605412232,-0.04134201322447215,0.38293496406007926,0.522950800501484,2.7297697351237553,2.795323733143928,0.8931505508985713,-0.37610541469729714,2.8389698027358996,-1.2346016602834036,-1.1347246437212606,-0.32800834772899334,-0.04134201322447215
| 3,067
|
Muscle fiber atrophy
| 7
| 19
| 1.967945
| 0.049074
|
P61978,Q9BTV4,Q99720,P23786,P35637,P22626,P50402
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
215,386,17,147,149,463,281
|
898,2802,461,463,147,149,281,2237,215,697,1884,725,2416,1720,1177,775,17,386,1100
|
0.24223217662498808,-0.9117717140860812,0.5927088870625801,0.5927088870625801,1.3952290840127508,1.3952290840127508,0.9391154562432038,-0.40018942775227584,1.0994747445642425,0.38293496406007926,-0.2081715578352066,0.3595328957429135,-0.49676620728557386,-0.13654115282560736,0.10081598985120394,0.33611163062394667,4.2982861261730845,0.7317400515807754,0.14803569668995656
| 3,067
|
Abnormal femoral neck head morphology
| 7
| 45
| 1.965726
| 0.04933
|
O75718,Q9H173,O95831,Q96HY6,Q14739,O75844,P46100
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
6,168,14,51,182,58,61
|
1102,2904,2952,2397,1205,1571,6,58,14,898,1458,2183,2907,2599,1214,1068,355,2191,61,2846,2100,722,1525,2240,182,1595,1171,2826,808,2894,1083,2679,1431,1486,51,1341,168,2045,3001,1993,1899,1393,784,1197,203
|
0.12443607605412232,-1.1846005429298558,-1.3601684318707938,-0.49676620728557386,0.0771753025605692,-0.08889808473863031,5.592772581581793,2.5764078869149727,4.6563469220776925,0.24223217662498808,-0.04134201322447215,-0.37610541469729714,-1.1846005429298558,-0.6423742870091806,0.0771753025605692,0.14803569668995656,0.7779431050658644,-0.37610541469729714,2.5105058405134244,-0.9858252312843699,-0.32800834772899334,0.3595328957429135,-0.06510924961463846,-0.40018942775227584,1.2135360793065495,-0.08889808473863031,0.10081598985120394,-0.9364275680017444,0.31267104849579785,-1.109832915775756,0.14803569668995656,-0.7155242386586748,-0.017596227567052123,-0.04134201322447215,2.7297697351237553,0.029831574171165644,1.2590511132682145,-0.28000473103222856,-1.7678418524139115,-0.25603753973957905,-0.2081715578352066,0.006128253475181141,0.33611163062394667,0.10081598985120394,1.145146616611409
| 3,067
|
transporter
| 21
| 61
| 3.80666
| 0.000141
|
Q9H2V7,Q9HD45,Q9NR77,Q99595,O43772,P39210,Q99567,Q15070,Q7Z3B4,Q9Y584,O60830,Q567V2,Q99805,Q92973,P53985,Q6N075,P41440,P62072,Q8NFH4,Q8N1F7,O43681
|
Functions
|
Panther Protein class
|
panther_protein_class
|
128,393,0,5,7,140,402,399,406,153,27,32,427,443,55,188,69,71,205,352,375
|
1831,1278,1202,1327,2956,1951,853,1283,375,7,958,27,990,1333,1675,1290,140,69,2242,1840,461,1492,1214,2602,55,1608,1415,523,580,2523,71,617,1027,399,32,188,406,352,1266,205,2219,660,1537,443,643,402,5,427,587,2468,1004,128,2636,393,0,3005,2472,1321,153,2614,1047
|
-0.2687463774668492,0.030850084923550944,0.07218715987352683,0.010049356609845118,-1.4056323712733998,-0.3354046675661042,0.33264549575231883,0.030850084923550944,0.9197953633069056,4.1654432084268365,0.2539802870628444,3.475825517493468,0.2341133298905719,0.010049356609845118,-0.18125720694712386,0.030850084923550944,1.786611952471423,2.519440449494305,-0.4945574879422671,-0.2687463774668492,0.7795641591048054,-0.07405196659429947,0.07218715987352683,-0.7555558469531406,2.7009867150585474,-0.13809249703546148,-0.031820131489916866,0.6898018853113626,0.5983391977919877,-0.6829914580738592,2.5070839778403435,0.5612639595076085,0.21416484143938402,0.8851185038122356,3.3225382570332864,1.458505765790809,0.8676859490502526,0.9713465029462117,0.051562445642740554,1.3806782934951933,-0.4715029980224777,0.5239023754686642,-0.09530566340648955,0.81500648275305,0.5426192269625886,0.8851185038122356,4.4424516811688495,0.8326303861028213,0.5983391977919877,-0.6352021957308768,0.2341133298905719,1.8581269973639303,-0.7799832529313712,0.9024881631846431,5.129020836832448,-1.7210140739331303,-0.6352021957308768,0.030850084923550944,1.6993479647673133,-0.7555558469531406,0.21416484143938402
| 3,069
|
Lysosomal lumen
| 16
| 32
| 3.573103
| 0.000353
|
P07602,O00584,P54802,P16278,Q8IV08,Q14108,P06865,P10253,P50897,Q13510,Q8NHP8,Q9UMR5,P10619,O14773,P04062,P11117
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
33,162,100,101,39,41,106,355,46,175,78,110,121,89,376,220
|
162,3011,89,375,376,578,483,106,33,651,1955,1055,355,121,220,2063,1409,652,101,902,1057,1018,46,100,175,41,39,1361,78,800,1272,110
|
1.6104528839435324,-1.7805588252111975,2.252883247492375,0.9197953633069056,0.9197953633069056,0.5983391977919877,0.7438593924757614,2.0254872721470325,3.3121366390002813,0.5239023754686642,-0.3354046675661042,0.19413417400581515,0.9542241080917176,1.9145729797153146,1.3015623258049298,-0.40298195769845385,-0.031820131489916866,0.5239023754686642,2.0935117653992443,0.2934721608296331,0.19413417400581515,0.21416484143938402,2.9325936953118417,2.1204499143061035,1.550253920627543,3.0221139040042435,3.033184055432667,0.010049356609845118,2.4196669404886824,0.39081896508326114,0.051562445642740554,1.9980012684894612
| 3,069
|
Protein localization
| 31
| 77
| 3.482976
| 0.000496
|
Q9NR77,Q8N4H5,Q99595,P25705,P39210,P46379,Q9NS69,Q9Y584,O60830,P21796,Q10713,Q9NX63,P40855,Q8N4Q1,O75381,P09601,Q13011,Q15067,O14925,P62072,Q8NBU5,O15254,O75431,P56589,Q3ZCQ8,P34913,O96008,P50402,Q5JRX3,Q13505,O43681
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,130,5,263,140,17,20,153,27,29,536,556,423,548,170,43,45,299,563,71,585,77,329,331,472,594,614,366,369,117,375
|
987,626,563,761,852,77,1283,375,899,2310,830,27,170,2760,329,2150,2568,1670,687,1601,614,783,1153,2922,43,2775,1205,2416,1522,29,2105,263,1720,594,1962,2650,140,423,17,1210,366,754,1644,331,2653,71,536,45,2285,117,299,472,369,816,1849,130,548,585,916,2789,1312,5,2338,820,719,2583,0,20,556,1318,1174,1147,2641,1399,153,1865,3021
|
0.2341133298905719,0.5426192269625886,0.6167707540458557,0.4100561090046764,0.33264549575231883,2.4322550310698223,0.030850084923550944,0.9197953633069056,0.2934721608296331,-0.540993539152877,0.35211425239127736,3.475825517493468,1.5804484768707614,-0.9291418506117229,1.0054094308154349,-0.44855622173737325,-0.731248835894527,-0.18125720694712386,0.4862501500603866,-0.13809249703546148,0.5612639595076085,0.39081896508326114,0.11317649001570981,-1.2416662214532936,2.966365414770548,-0.9544453152528625,0.07218715987352683,-0.6114803864575494,-0.09530566340648955,3.3741993459998163,-0.4257161927970913,1.1721916646896646,-0.20298328683847608,0.5798371070730094,-0.3354046675661042,-0.8045322091109726,1.786611952471423,0.8326303861028213,3.682239434852251,0.07218715987352683,0.9370405358529817,0.42921722537504836,-0.1596272157387103,1.0054094308154349,-0.8045322091109726,2.5070839778403435,0.6716473552783213,2.943878112382939,-0.5177206708014539,1.9564707654985696,1.089524939627866,0.7617448151371171,0.9370405358529817,0.37150520972870915,-0.2687463774668492,1.829650134972895,0.6534243244188832,0.5983391977919877,0.2934721608296331,-0.9544453152528625,0.030850084923550944,4.4424516811688495,-0.540993539152877,0.37150520972870915,0.46731367824728265,-0.731248835894527,5.129020836832448,3.6241989583234373,0.6534243244188832,0.030850084923550944,0.11317649001570981,0.13354250527191597,-0.7799832529313712,-0.010840469228635595,1.6993479647673133,-0.2687463774668492,-1.871225423943587
| 3,069
|
Sensorimotor neuropathy
| 11
| 32
| 3.41354
| 0.000641
|
Q5KU26,Q9NR77,P07602,Q9Y2R0,O95831,P41440,P03915,P07196,P39210,P00846,P00403
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
258,0,33,66,64,69,229,108,140,15,85
|
1326,1079,900,64,85,15,229,1483,108,33,2157,2160,140,1985,69,1212,1644,2071,2571,1419,484,2914,258,2362,1502,714,1037,0,347,1272,66,805
|
0.010049356609845118,0.1740206722343724,0.2934721608296331,2.5440562997072673,2.3048330176200653,3.7961743788849853,1.2534569702074796,-0.07405196659429947,1.9980012684894612,3.3121366390002813,-0.44855622173737325,-0.44855622173737325,1.786611952471423,-0.35782711761202085,2.519440449494305,0.07218715987352683,-0.1596272157387103,-0.40298195769845385,-0.731248835894527,-0.031820131489916866,0.7438593924757614,-1.2148568573039746,1.1885553643741225,-0.5643770990360283,-0.07405196659429947,0.46731367824728265,0.21416484143938402,5.129020836832448,0.9884081390522009,0.051562445642740554,2.5440562997072673,0.39081896508326114
| 3,069
|
Peripheral axonal degeneration
| 17
| 66
| 3.305392
| 0.000948
|
P50570,P07602,O95831,P41440,P02545,Q8IV08,P03915,P07196,P39210,Q15067,P00846,P00403,Q9BQT8,Q6DKK2,P22626,Q96BR5,Q9BPX6
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
320,33,64,69,262,39,229,108,140,299,15,85,245,123,349,416,159
|
2376,778,1079,2413,900,1477,1408,2151,64,85,15,262,229,1053,108,2818,33,2316,832,1205,421,1838,349,2421,786,2160,140,2203,69,1347,1986,320,2206,2386,1725,2071,2030,1764,1419,997,2997,2250,299,2252,2575,2123,2362,123,1814,1530,39,1427,916,714,416,2135,159,245,2137,2470,1512,951,1272,2054,805,1325
|
-0.5878723702209245,0.39081896508326114,0.1740206722343724,-0.6114803864575494,0.2934721608296331,-0.07405196659429947,-0.031820131489916866,-0.44855622173737325,2.5440562997072673,2.3048330176200653,3.7961743788849853,1.1721916646896646,1.2534569702074796,0.19413417400581515,1.9980012684894612,-1.005443892780752,3.3121366390002813,-0.540993539152877,0.35211425239127736,0.07218715987352683,0.8326303861028213,-0.2687463774668492,0.9713465029462117,-0.6114803864575494,0.39081896508326114,-0.44855622173737325,1.786611952471423,-0.4715029980224777,2.519440449494305,0.010049356609845118,-0.35782711761202085,1.0392326181245326,-0.4715029980224777,-0.5878723702209245,-0.20298328683847608,-0.40298195769845385,-0.3803525755016717,-0.2248062819916635,-0.031820131489916866,0.2341133298905719,-1.6621699792153193,-0.4945574879422671,1.089524939627866,-0.4945574879422671,-0.731248835894527,-0.4257161927970913,-0.5643770990360283,1.886433964311089,-0.24672702956312,-0.09530566340648955,3.033184055432667,-0.031820131489916866,0.2934721608296331,0.46731367824728265,0.8501900582323448,-0.4257161927970913,1.625384500578365,1.2211160826760208,-0.4257161927970913,-0.6352021957308768,-0.07405196659429947,0.2737663531255464,0.051562445642740554,-0.3803525755016717,0.39081896508326114,0.030850084923550944
| 3,069
|
Inorganic molecular entity transmembrane transporter activity
| 29
| 79
| 3.257581
| 0.001124
|
Q9UDW1,Q8TAD4,Q93050,Q15043,P25705,P08133,O15439,P00846,Q8TDW0,P45880,P21796,P51790,Q9Y277,Q9Y487,Q96QD8,Q6N075,Q9Y5K8,O75964,Q9H2J7,P16615,Q13423,Q9HD20,P00403,Q9C0H2,P35670,Q6P4Q7,Q96ES6,Q9UBX3,O43681
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
132,135,8,264,263,385,137,15,415,28,29,414,429,42,444,188,455,199,335,458,83,84,85,94,224,232,513,253,375
|
2409,1750,137,375,2015,199,1332,85,15,1483,1336,2761,783,1203,385,629,1153,3019,1557,1205,2201,458,1524,834,1719,2821,29,785,263,2239,224,2320,992,2278,28,1020,2989,414,3000,2113,2359,2522,1842,2523,2427,2551,83,264,1110,188,232,1264,1265,1852,135,415,2043,8,1773,513,444,3047,1392,94,2184,335,84,2637,253,132,2055,1122,429,1948,42,455,2308,1949,516
|
-0.6114803864575494,-0.2248062819916635,1.786611952471423,0.9197953633069056,-0.3803525755016717,1.3963455650807735,0.010049356609845118,2.3048330176200653,3.7961743788849853,-0.07405196659429947,0.010049356609845118,-0.9291418506117229,0.39081896508326114,0.07218715987352683,0.9024881631846431,0.5426192269625886,0.11317649001570981,-1.871225423943587,-0.11665224488806318,0.07218715987352683,-0.4715029980224777,0.7795641591048054,-0.09530566340648955,0.35211425239127736,-0.20298328683847608,-1.005443892780752,3.3741993459998163,0.39081896508326114,1.1721916646896646,-0.4945574879422671,1.2855808712415313,-0.540993539152877,0.2341133298905719,-0.5177206708014539,3.4455710952889245,0.21416484143938402,-1.6040108138088613,0.8501900582323448,-1.6915054398535807,-0.4257161927970913,-0.5643770990360283,-0.6829914580738592,-0.2687463774668492,-0.6829914580738592,-0.6114803864575494,-0.7070610806666029,2.3562163638412286,1.1721916646896646,0.15382367299729152,1.458505765790809,1.2534569702074796,0.051562445642740554,0.051562445642740554,-0.2687463774668492,1.801001399719216,0.8501900582323448,-0.3803525755016717,4.1654432084268365,-0.2248062819916635,0.7078884093515075,0.81500648275305,-2.5214717639102737,-0.010840469228635595,2.2135419004040315,-0.44855622173737325,1.0054094308154349,2.330594748206502,-0.7799832529313712,1.204863382292912,1.829650134972895,-0.3803525755016717,0.15382367299729152,0.8326303861028213,-0.31308432082275484,2.999894420961043,0.797317893556882,-0.5177206708014539,-0.31308432082275484,0.7078884093515075
| 3,069
|
Tetrapyrrole binding
| 6
| 16
| 3.248575
| 0.00116
|
P53701,Q8WUJ1,O43169,P09601,P30519,Q16850
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
97,2,74,43,19,31
|
517,328,74,1153,43,1755,19,97,31,126,1264,2,2294,1703,554,588
|
0.6898018853113626,1.0054094308154349,2.482273117142744,0.11317649001570981,2.966365414770548,-0.2248062819916635,3.6629735845084817,2.147235382078263,3.3329166087539415,1.8723015954974838,0.051562445642740554,4.7418817648624305,-0.5177206708014539,-0.18125720694712386,0.6534243244188832,0.5983391977919877
| 3,069
|
Lysosome
| 24
| 50
| 3.223028
| 0.001268
|
Q93050,P11717,Q9Y2T2,P07602,Q14108,Q9Y487,P50897,Q13510,O75503,Q92572,O14773,P11117,P20645,Q99523,P54802,P16278,P06865,P10253,Q8NCC3,Q9UMR5,O15118,P10619,P04062,O43681
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
8,269,282,33,41,42,46,175,72,476,89,220,96,488,100,101,106,355,109,110,120,121,376,375
|
2674,3011,2956,89,120,375,2615,72,376,578,483,106,33,651,1055,1915,2819,355,121,220,1204,269,1409,652,101,902,96,1018,46,2923,100,3029,1842,2328,909,175,41,547,109,476,8,488,1542,1272,2055,744,2473,110,282,42
|
-0.8292038872729048,-1.7805588252111975,-1.4056323712733998,2.252883247492375,1.9145729797153146,0.9197953633069056,-0.7799832529313712,2.494694922423651,0.9197953633069056,0.5983391977919877,0.7438593924757614,2.0254872721470325,3.3121366390002813,0.5239023754686642,0.19413417400581515,-0.31308432082275484,-1.005443892780752,0.9542241080917176,1.9145729797153146,1.3015623258049298,0.07218715987352683,1.1557719154454555,-0.031820131489916866,0.5239023754686642,2.0935117653992443,0.2934721608296331,2.1871309307140887,0.21416484143938402,2.9325936953118417,-1.2416662214532936,2.1204499143061035,-2.0576306133474436,-0.2687463774668492,-0.540993539152877,0.2934721608296331,1.550253920627543,3.0221139040042435,0.6534243244188832,1.9980012684894612,0.7617448151371171,4.1654432084268365,0.7438593924757614,-0.09530566340648955,0.051562445642740554,-0.3803525755016717,0.44830289150821834,-0.6352021957308768,1.9980012684894612,1.1392957452369128,2.999894420961043
| 3,069
|
External side of plasma membrane
| 8
| 22
| 3.20936
| 0.00133
|
P41440,P55899,O15439,P00813,P02786,P08183,O96005,P42892
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
69,289,137,16,396,53,365,23
|
137,1407,365,901,16,396,1520,1252,1015,53,1204,1522,2515,2108,69,23,2112,414,289,1691,1224,638
|
1.786611952471423,-0.031820131489916866,0.9370405358529817,0.2934721608296331,3.7205314479190315,0.8851185038122356,-0.09530566340648955,0.051562445642740554,0.21416484143938402,2.771680946122683,0.07218715987352683,-0.09530566340648955,-0.6829914580738592,-0.4257161927970913,2.519440449494305,3.5258141843000015,-0.4257161927970913,0.8501900582323448,1.10617263797279,-0.18125720694712386,0.07218715987352683,0.5426192269625886
| 3,069
|
Sphingolipid metabolic process
| 13
| 28
| 3.208457
| 0.001334
|
P07602,Q99805,P16278,Q96G23,Q06136,P06865,P06280,Q8NCC3,P50897,Q13510,O15121,P27544,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,427,101,141,357,106,483,109,46,175,215,277,376
|
215,778,1079,2017,376,483,106,33,651,101,902,1017,277,1383,46,1684,357,175,2037,1577,109,141,427,2404,985,1272,562,1318
|
1.3174905758707651,0.39081896508326114,0.1740206722343724,-0.3803525755016717,0.9197953633069056,0.7438593924757614,2.0254872721470325,3.3121366390002813,0.5239023754686642,2.0935117653992443,0.2934721608296331,0.21416484143938402,1.1392957452369128,-0.010840469228635595,2.9325936953118417,-0.18125720694712386,0.9542241080917176,1.550253920627543,-0.3803525755016717,-0.11665224488806318,1.9980012684894612,1.786611952471423,0.8326303861028213,-0.5878723702209245,0.2539802870628444,0.051562445642740554,0.6351322925467491,0.030850084923550944
| 3,069
|
Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen
| 12
| 29
| 3.147008
| 0.00165
|
Q32P28,P09601,Q15800,P30519,P61457,Q9BU89,Q8NB78,O15121,O15460,Q6UW02,P16435,Q16850
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
326,43,187,19,367,87,316,215,283,126,470,31
|
1832,215,283,1050,1551,855,856,1015,43,504,470,904,19,367,1764,1883,1575,187,31,326,126,2217,2174,791,316,87,1316,1005,2191
|
-0.2687463774668492,1.3174905758707651,1.122762779001896,0.19413417400581515,-0.11665224488806318,0.33264549575231883,0.33264549575231883,0.21416484143938402,2.966365414770548,0.7078884093515075,0.7617448151371171,0.2934721608296331,3.6629735845084817,0.9370405358529817,-0.2248062819916635,-0.29086518455841137,-0.11665224488806318,1.458505765790809,3.3329166087539415,1.0223507884681426,1.8723015954974838,-0.4715029980224777,-0.44855622173737325,0.39081896508326114,1.0560553218353965,2.2789296869171887,0.030850084923550944,0.2341133298905719,-0.44855622173737325
| 3,069
|
Cation transmembrane transporter activity
| 23
| 74
| 3.141964
| 0.001678
|
Q9UDW1,Q8TAD4,Q93050,Q15043,O43772,P25705,P08133,P00846,P51790,Q9Y487,Q96QD8,Q70HW3,Q9Y5K8,P30825,O75964,Q9H2J7,P16615,Q13423,Q9HD20,P00403,P35670,Q6P4Q7,Q96ES6
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
132,135,8,264,7,263,385,15,414,42,444,61,455,73,199,335,458,83,84,85,224,232,513
|
1750,7,2310,2015,199,1332,85,15,1483,1336,2761,783,1203,385,629,1153,1557,1205,2201,458,1524,834,1719,2821,785,263,73,2239,224,2320,992,2278,1020,2989,414,2113,2359,2522,1842,2523,2427,83,264,756,1110,232,61,1264,1852,602,135,2043,8,1773,513,1097,444,3047,587,2184,335,1778,2470,84,2637,132,2055,1122,1948,42,455,1047,2308,516
|
-0.2248062819916635,4.1654432084268365,-0.540993539152877,-0.3803525755016717,1.3963455650807735,0.010049356609845118,2.3048330176200653,3.7961743788849853,-0.07405196659429947,0.010049356609845118,-0.9291418506117229,0.39081896508326114,0.07218715987352683,0.9024881631846431,0.5426192269625886,0.11317649001570981,-0.11665224488806318,0.07218715987352683,-0.4715029980224777,0.7795641591048054,-0.09530566340648955,0.35211425239127736,-0.20298328683847608,-1.005443892780752,0.39081896508326114,1.1721916646896646,2.494694922423651,-0.4945574879422671,1.2855808712415313,-0.540993539152877,0.2341133298905719,-0.5177206708014539,0.21416484143938402,-1.6040108138088613,0.8501900582323448,-0.4257161927970913,-0.5643770990360283,-0.6829914580738592,-0.2687463774668492,-0.6829914580738592,-0.6114803864575494,2.3562163638412286,1.1721916646896646,0.42921722537504836,0.15382367299729152,1.2534569702074796,2.629209225162519,0.051562445642740554,-0.2687463774668492,0.5798371070730094,1.801001399719216,-0.3803525755016717,4.1654432084268365,-0.2248062819916635,0.7078884093515075,0.1740206722343724,0.81500648275305,-2.5214717639102737,0.5983391977919877,-0.44855622173737325,1.0054094308154349,-0.2248062819916635,-0.6352021957308768,2.330594748206502,-0.7799832529313712,1.829650134972895,-0.3803525755016717,0.15382367299729152,-0.31308432082275484,2.999894420961043,0.797317893556882,0.21416484143938402,-0.5177206708014539,0.7078884093515075
| 3,069
|
Vacuolar lumen
| 21
| 61
| 3.105515
| 0.001899
|
Q99536,P07602,O00584,Q8IV08,Q14108,P78371,Q13510,P50897,P68371,Q8NHP8,O14773,P11117,P54802,P16278,P06865,P10253,Q9UMR5,Q9BTY2,P10619,P04062,O43681
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
408,33,162,39,41,298,175,46,312,78,89,220,100,101,106,355,110,112,121,376,375
|
162,3011,89,375,1555,376,578,483,106,1203,410,33,651,1955,1055,355,121,220,2063,1602,1409,652,101,902,1960,2979,1057,1018,1184,46,2070,2546,2923,1215,100,2071,1294,312,298,1881,1684,484,175,41,2997,39,1361,78,1891,973,1237,408,3051,112,800,2935,554,2792,1272,110,2093
|
1.6104528839435324,-1.7805588252111975,2.252883247492375,0.9197953633069056,-0.11665224488806318,0.9197953633069056,0.5983391977919877,0.7438593924757614,2.0254872721470325,0.07218715987352683,0.8501900582323448,3.3121366390002813,0.5239023754686642,-0.3354046675661042,0.19413417400581515,0.9542241080917176,1.9145729797153146,1.3015623258049298,-0.40298195769845385,-0.13809249703546148,-0.031820131489916866,0.5239023754686642,2.0935117653992443,0.2934721608296331,-0.3354046675661042,-1.5465213678572585,0.19413417400581515,0.21416484143938402,0.09272494003870865,2.9325936953118417,-0.40298195769845385,-0.7070610806666029,-1.2416662214532936,0.07218715987352683,2.1204499143061035,-0.40298195769845385,0.030850084923550944,1.0560553218353965,1.089524939627866,-0.29086518455841137,-0.18125720694712386,0.7438593924757614,1.550253920627543,3.0221139040042435,-1.6621699792153193,3.033184055432667,0.010049356609845118,2.4196669404886824,-0.29086518455841137,0.2539802870628444,0.07218715987352683,0.8676859490502526,-2.698023469153992,1.984198193350699,0.39081896508326114,-1.268621087792348,0.6534243244188832,-0.9544453152528625,0.051562445642740554,1.9980012684894612,-0.40298195769845385
| 3,069
|
Abnormality of head blood vessel
| 7
| 25
| 3.095629
| 0.001964
|
P07602,P16278,P06865,P21964,Q13510,P00846,P10619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
33,101,106,11,175,15,121
|
2966,1401,1179,15,229,106,33,651,121,2417,101,902,2452,11,1488,1386,2426,1221,175,2786,1002,2042,1272,2008,2192
|
-1.4615108644803487,-0.031820131489916866,0.09272494003870865,3.7961743788849853,1.2534569702074796,2.0254872721470325,3.3121366390002813,0.5239023754686642,1.9145729797153146,-0.6114803864575494,2.0935117653992443,0.2934721608296331,-0.6352021957308768,4.060404520025005,-0.07405196659429947,-0.010840469228635595,-0.6114803864575494,0.07218715987352683,1.550253920627543,-0.9544453152528625,0.2341133298905719,-0.3803525755016717,0.051562445642740554,-0.35782711761202085,-0.44855622173737325
| 3,069
|
Mitochondrial transmembrane transport
| 14
| 52
| 3.041281
| 0.002356
|
O95831,Q99595,P25705,O43772,O75964,O75027,P23786,P00846,Q8WWC4,Q9BQT8,Q9H4I9,O60830,P21796,Q9BPX6
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,5,263,7,199,202,236,15,240,245,122,27,29,159
|
563,1283,7,27,202,2150,1670,2015,199,1601,1332,2377,64,614,15,2761,783,2775,1205,2416,29,236,785,263,2320,2989,2425,2602,2359,2522,2427,2736,472,789,273,548,1852,2395,240,681,1773,1097,5,159,245,122,1778,2583,1174,1321,805,1047
|
0.6167707540458557,0.030850084923550944,4.1654432084268365,3.475825517493468,1.3806782934951933,-0.44855622173737325,-0.18125720694712386,-0.3803525755016717,1.3963455650807735,-0.13809249703546148,0.010049356609845118,-0.5878723702209245,2.5440562997072673,0.5612639595076085,3.7961743788849853,-0.9291418506117229,0.39081896508326114,-0.9544453152528625,0.07218715987352683,-0.6114803864575494,3.3741993459998163,1.2373138262349093,0.39081896508326114,1.1721916646896646,-0.540993539152877,-1.6040108138088613,-0.6114803864575494,-0.7555558469531406,-0.5643770990360283,-0.6829914580738592,-0.6114803864575494,-0.8789201810531422,0.7617448151371171,0.39081896508326114,1.1557719154454555,0.6534243244188832,-0.2687463774668492,-0.5878723702209245,1.2373138262349093,0.5051128651347058,-0.2248062819916635,0.1740206722343724,4.4424516811688495,1.625384500578365,1.2211160826760208,1.9145729797153146,-0.2248062819916635,-0.731248835894527,0.11317649001570981,0.030850084923550944,0.39081896508326114,0.21416484143938402
| 3,069
|
Abnormal retinal artery morphology
| 7
| 22
| 3.03206
| 0.002429
|
P07602,P16278,P06865,P21964,Q13510,P00846,P10619
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
33,101,106,11,175,15,121
|
2966,1179,15,229,106,33,651,121,2417,101,902,11,1488,2426,1221,175,2786,1002,2042,1272,2008,2192
|
-1.4615108644803487,0.09272494003870865,3.7961743788849853,1.2534569702074796,2.0254872721470325,3.3121366390002813,0.5239023754686642,1.9145729797153146,-0.6114803864575494,2.0935117653992443,0.2934721608296331,4.060404520025005,-0.07405196659429947,-0.6114803864575494,0.07218715987352683,1.550253920627543,-0.9544453152528625,0.2341133298905719,-0.3803525755016717,0.051562445642740554,-0.35782711761202085,-0.44855622173737325
| 3,069
|
Membrane lipid metabolic process
| 15
| 36
| 3.003939
| 0.002665
|
P07602,P04062,Q99805,P16278,Q96G23,Q06136,P06865,P06280,Q8NCC3,P50897,Q9P035,Q13510,O15121,P27544,Q8NBX0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,376,427,101,141,357,106,483,109,46,562,175,215,277,25
|
215,778,1079,1379,2449,2017,376,578,483,106,33,651,101,902,1017,277,1383,46,1684,357,175,2037,1577,25,109,1854,141,2538,1624,427,801,2404,985,1272,562,1318
|
1.3174905758707651,0.39081896508326114,0.1740206722343724,-0.010840469228635595,-0.6352021957308768,-0.3803525755016717,0.9197953633069056,0.5983391977919877,0.7438593924757614,2.0254872721470325,3.3121366390002813,0.5239023754686642,2.0935117653992443,0.2934721608296331,0.21416484143938402,1.1392957452369128,-0.010840469228635595,2.9325936953118417,-0.18125720694712386,0.9542241080917176,1.550253920627543,-0.3803525755016717,-0.11665224488806318,3.5158595652945293,1.9980012684894612,-0.2687463774668492,1.786611952471423,-0.6829914580738592,-0.13809249703546148,0.8326303861028213,0.39081896508326114,-0.5878723702209245,0.2539802870628444,0.051562445642740554,0.6351322925467491,0.030850084923550944
| 3,069
|
Mitochondrial transport
| 20
| 85
| 3.0011
| 0.00269
|
Q8N4H5,Q99595,O43772,P25705,P00846,P30536,Q9NS69,Q9Y584,O60830,P45880,P55786,Q96EK5,O95831,P62072,O75964,O75431,P23786,Q8WWC4,Q5JRX3,Q9UBX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,5,7,263,15,144,20,153,27,28,54,321,64,71,199,329,236,240,369,253
|
612,1277,518,563,1283,7,830,27,329,2150,2015,199,1601,1408,2728,2151,64,614,15,1334,2761,783,1955,1381,2775,1205,2451,236,785,263,1757,2276,144,2595,2320,2240,28,2989,835,1563,2823,2425,730,906,54,2359,2522,71,2163,536,399,2660,472,1577,369,1064,2840,867,1308,130,548,1266,916,240,321,1540,1369,5,1392,2668,2583,2003,20,1146,1375,2813,253,647,1174,1321,1147,2094,1399,153,1865
|
0.5612639595076085,0.030850084923550944,0.6898018853113626,0.6167707540458557,0.030850084923550944,4.1654432084268365,0.35211425239127736,3.475825517493468,1.0054094308154349,-0.44855622173737325,-0.3803525755016717,1.3963455650807735,-0.13809249703546148,-0.031820131489916866,-0.8789201810531422,-0.44855622173737325,2.5440562997072673,0.5612639595076085,3.7961743788849853,0.010049356609845118,-0.9291418506117229,0.39081896508326114,-0.3354046675661042,-0.010840469228635595,-0.9544453152528625,0.07218715987352683,-0.6352021957308768,1.2373138262349093,0.39081896508326114,1.1721916646896646,-0.2248062819916635,-0.5177206708014539,1.7721787798962068,-0.7555558469531406,-0.540993539152877,-0.4945574879422671,3.4455710952889245,-1.6040108138088613,0.35211425239127736,-0.11665224488806318,-1.005443892780752,-0.6114803864575494,0.44830289150821834,0.2934721608296331,2.7364672632965075,-0.5643770990360283,-0.6829914580738592,2.5070839778403435,-0.44855622173737325,0.6716473552783213,0.8851185038122356,-0.8045322091109726,0.7617448151371171,-0.11665224488806318,0.9370405358529817,0.19413417400581515,-1.0311416178800303,0.33264549575231883,0.030850084923550944,1.829650134972895,0.6534243244188832,0.051562445642740554,0.2934721608296331,1.2373138262349093,1.0392326181245326,-0.09530566340648955,0.010049356609845118,4.4424516811688495,-0.010840469228635595,-0.8045322091109726,-0.731248835894527,-0.35782711761202085,3.6241989583234373,0.13354250527191597,0.010049356609845118,-0.9798788971454372,1.204863382292912,0.5426192269625886,0.11317649001570981,0.030850084923550944,0.13354250527191597,-0.40298195769845385,-0.010840469228635595,1.6993479647673133,-0.2687463774668492
| 3,069
|
Ion transport
| 25
| 63
| 2.98322
| 0.002852
|
P25705,Q93050,Q15043,Q8TAD4,P00846,Q8TDW0,P45880,P51790,P21796,Q9BPX6,Q9Y277,Q15904,Q9Y487,Q96QD8,Q6N075,Q9Y5K8,O75964,Q9H2J7,P16615,Q9C0H2,P35670,Q6P4Q7,Q9H0H5,Q9H4I9,Q9Y6M7
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
263,8,264,135,15,415,28,414,29,159,429,547,42,444,188,455,199,335,458,94,224,232,503,122,516
|
2409,2015,199,1332,614,15,1483,1336,783,3019,458,1524,1719,2821,29,785,263,224,2320,992,2278,28,2989,414,3000,2720,2113,2359,2522,1842,658,1086,264,547,1110,188,232,1265,549,1852,602,135,415,8,681,1773,444,3047,159,1464,94,503,335,122,2055,1122,429,1948,42,455,2308,1949,516
|
-0.6114803864575494,-0.3803525755016717,1.3963455650807735,0.010049356609845118,0.5612639595076085,3.7961743788849853,-0.07405196659429947,0.010049356609845118,0.39081896508326114,-1.871225423943587,0.7795641591048054,-0.09530566340648955,-0.20298328683847608,-1.005443892780752,3.3741993459998163,0.39081896508326114,1.1721916646896646,1.2855808712415313,-0.540993539152877,0.2341133298905719,-0.5177206708014539,3.4455710952889245,-1.6040108138088613,0.8501900582323448,-1.6915054398535807,-0.8539994760110062,-0.4257161927970913,-0.5643770990360283,-0.6829914580738592,-0.2687463774668492,0.5239023754686642,0.1740206722343724,1.1721916646896646,0.6534243244188832,0.15382367299729152,1.458505765790809,1.2534569702074796,0.051562445642740554,0.6534243244188832,-0.2687463774668492,0.5798371070730094,1.801001399719216,0.8501900582323448,4.1654432084268365,0.5051128651347058,-0.2248062819916635,0.81500648275305,-2.5214717639102737,1.625384500578365,-0.05289037818638174,2.2135419004040315,0.7259074169551265,1.0054094308154349,1.9145729797153146,-0.3803525755016717,0.15382367299729152,0.8326303861028213,-0.31308432082275484,2.999894420961043,0.797317893556882,-0.5177206708014539,-0.31308432082275484,0.7078884093515075
| 3,069
|
Inner mitochondrial membrane protein complex
| 27
| 78
| 2.955789
| 0.003119
|
Q9UDW1,Q99595,P25705,Q16891,P00846,Q8IYU8,O96000,P21912,Q9Y584,O60830,Q5HYI7,Q9BPX6,Q9NX63,O43674,P22695,Q96CU9,Q5XKP0,P62072,O75964,O75431,O43676,P00403,Q3ZCQ8,O14949,P03915,Q13505,Q9H4I9
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
132,5,263,526,15,273,146,397,153,27,285,159,556,418,296,49,570,71,199,329,80,85,472,480,229,117,122
|
2875,1751,563,480,418,80,2148,27,2587,613,2617,329,2014,2015,199,1151,2016,146,85,15,229,783,1153,2236,1557,2416,2201,1957,2065,2621,2799,834,397,296,785,263,2712,2024,2239,2277,2320,2650,1020,2989,1879,1987,2359,2522,71,117,1968,2531,526,472,1577,285,570,1652,1307,273,1852,49,1366,5,2372,159,122,2583,1630,556,1146,132,1147,2307,805,1399,153,955
|
-1.1352868219192742,-0.2248062819916635,0.6167707540458557,0.7438593924757614,0.8326303861028213,2.3689750863745247,-0.44855622173737325,3.475825517493468,-0.7555558469531406,0.5612639595076085,-0.7799832529313712,1.0054094308154349,-0.3803525755016717,-0.3803525755016717,1.3963455650807735,0.11317649001570981,-0.3803525755016717,1.7577016250427588,2.3048330176200653,3.7961743788849853,1.2534569702074796,0.39081896508326114,0.11317649001570981,-0.4945574879422671,-0.11665224488806318,-0.6114803864575494,-0.4715029980224777,-0.3354046675661042,-0.40298195769845385,-0.7799832529313712,-0.9798788971454372,0.35211425239127736,0.8851185038122356,1.089524939627866,0.39081896508326114,1.1721916646896646,-0.8539994760110062,-0.3803525755016717,-0.4945574879422671,-0.5177206708014539,-0.540993539152877,-0.8045322091109726,0.21416484143938402,-1.6040108138088613,-0.29086518455841137,-0.35782711761202085,-0.5643770990360283,-0.6829914580738592,2.5070839778403435,1.9564707654985696,-0.3354046675661042,-0.6829914580738592,0.6898018853113626,0.7617448151371171,-0.11665224488806318,1.122762779001896,0.6167707540458557,-0.1596272157387103,0.030850084923550944,1.1557719154454555,-0.2687463774668492,2.898575851463229,0.010049356609845118,4.4424516811688495,-0.5643770990360283,1.625384500578365,1.9145729797153146,-0.731248835894527,-0.13809249703546148,0.6534243244188832,0.13354250527191597,1.829650134972895,0.13354250527191597,-0.5177206708014539,0.39081896508326114,-0.010840469228635595,1.6993479647673133,0.2737663531255464
| 3,069
|
Translocation
| 21
| 51
| 2.927387
| 0.003418
|
Q8TD16,Q99595,Q99567,P55735,Q9NS69,Q7Z3B4,Q9Y584,O60830,P12270,Q8N4Q1,O75381,P41208,Q8NFH5,Q9BTX1,O14925,P62072,P57740,Q8NFH4,Q3ZCQ8,Q8N1F7,Q15629
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
391,5,402,523,20,406,153,27,411,548,170,297,442,190,563,71,580,205,472,352,102
|
1831,2477,563,1283,830,27,170,990,411,1675,1290,297,1840,1291,1214,523,580,2653,2523,2854,71,2281,617,102,472,2081,406,352,548,2495,205,442,391,2219,1068,1267,1771,1141,402,5,190,894,1776,741,1512,20,825,2089,2445,153,1865
|
-0.2687463774668492,-0.6590388605217596,0.6167707540458557,0.030850084923550944,0.35211425239127736,3.475825517493468,1.5804484768707614,0.2341133298905719,0.8501900582323448,-0.18125720694712386,0.030850084923550944,1.089524939627866,-0.2687463774668492,0.030850084923550944,0.07218715987352683,0.6898018853113626,0.5983391977919877,-0.8045322091109726,-0.6829914580738592,-1.056973407774157,2.5070839778403435,-0.5177206708014539,0.5612639595076085,2.0935117653992443,0.7617448151371171,-0.40298195769845385,0.8676859490502526,0.9713465029462117,0.6534243244188832,-0.6590388605217596,1.3806782934951933,0.81500648275305,0.9024881631846431,-0.4715029980224777,0.19413417400581515,0.051562445642740554,-0.2248062819916635,0.13354250527191597,0.8851185038122356,4.4424516811688495,1.458505765790809,0.3130983356211,-0.2248062819916635,0.44830289150821834,-0.07405196659429947,3.6241989583234373,0.37150520972870915,-0.40298195769845385,-0.6114803864575494,1.6993479647673133,-0.2687463774668492
| 3,069
|
Anion transport
| 22
| 73
| 2.924999
| 0.003445
|
P14174,O43865,Q15043,O15439,P30536,Q8TDW0,P45880,P51790,P21796,P07602,Q9Y277,Q9UHG3,P08183,P53985,Q6N075,P41440,P30825,Q9H2J7,Q9C0H2,Q9BQT8,Q9UBX3,O43681
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
256,255,264,137,144,415,28,414,29,33,429,35,53,55,188,69,73,335,94,245,253,375
|
2409,1750,137,375,2310,255,1913,1670,1982,2377,1520,2761,1252,33,53,629,3019,2591,1205,2416,256,2452,29,1720,144,73,69,28,414,3000,2602,55,1608,2113,2427,2551,675,1765,636,888,3024,264,756,1110,188,1064,2696,1265,550,415,839,1097,444,587,245,94,503,335,1778,2470,1895,2637,1272,253,35,2843,1174,429,1948,1047,2308,1949,516
|
-0.6114803864575494,-0.2248062819916635,1.786611952471423,0.9197953633069056,-0.540993539152877,1.1885553643741225,-0.31308432082275484,-0.18125720694712386,-0.35782711761202085,-0.5878723702209245,-0.09530566340648955,-0.9291418506117229,0.051562445642740554,3.3121366390002813,2.771680946122683,0.5426192269625886,-1.871225423943587,-0.7555558469531406,0.07218715987352683,-0.6114803864575494,1.1885553643741225,-0.6352021957308768,3.3741993459998163,-0.20298328683847608,1.7721787798962068,2.494694922423651,2.519440449494305,3.4455710952889245,0.8501900582323448,-1.6915054398535807,-0.7555558469531406,2.7009867150585474,-0.13809249703546148,-0.4257161927970913,-0.6114803864575494,-0.7070610806666029,0.5051128651347058,-0.2248062819916635,0.5426192269625886,0.3130983356211,-1.9325942351876662,1.1721916646896646,0.42921722537504836,0.15382367299729152,1.458505765790809,0.19413417400581515,-0.8292038872729048,0.051562445642740554,0.6534243244188832,0.8501900582323448,0.35211425239127736,0.1740206722343724,0.81500648275305,0.5983391977919877,1.2211160826760208,2.2135419004040315,0.7259074169551265,1.0054094308154349,-0.2248062819916635,-0.6352021957308768,-0.29086518455841137,-0.7799832529313712,0.051562445642740554,1.204863382292912,3.249232648120622,-1.0311416178800303,0.11317649001570981,0.8326303861028213,-0.31308432082275484,0.21416484143938402,-0.5177206708014539,-0.31308432082275484,0.7078884093515075
| 3,069
|
Serine hydrolase activity
| 6
| 17
| 2.915555
| 0.003551
|
Q16740,O14773,P42785,Q9H3G5,P10619,Q9HB40
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
129,89,10,82,121,26
|
89,196,121,1339,2274,1919,10,1346,1214,2923,2074,129,438,369,1001,82,26
|
2.252883247492375,1.4275268034370876,1.9145729797153146,0.010049356609845118,-0.5177206708014539,-0.31308432082275484,4.130697126833025,0.010049356609845118,0.07218715987352683,-1.2416662214532936,-0.40298195769845385,1.829650134972895,0.81500648275305,0.9370405358529817,0.2341133298905719,2.3689750863745247,3.4958858354923237
| 3,069
|
Peptide binding
| 21
| 72
| 2.896692
| 0.003771
|
Q8WTV0,O00264,P42892,Q9Y584,P40855,O15212,P55899,Q03519,P10321,Q92973,P55786,Q14978,Q9UIQ6,Q15392,O43813,P52292,O14773,Q9NQX7,Q07954,P04439,Q9UHV9
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
13,517,23,153,423,287,289,172,306,443,54,437,56,58,311,461,89,103,105,494,254
|
1831,517,1278,1202,1327,89,287,1599,311,958,1601,1556,494,2352,1915,2819,306,1522,2622,2730,2108,2711,1757,2834,1385,1675,2800,423,23,2762,1839,1840,1291,461,1492,1214,54,289,2211,2523,788,2114,172,105,1418,1732,2553,734,1027,437,58,818,660,13,443,795,2608,2222,1624,894,2138,1824,554,2141,103,2443,1547,1780,254,56,2011,153
|
-0.2687463774668492,0.6898018853113626,0.030850084923550944,0.07218715987352683,0.010049356609845118,2.252883247492375,1.10617263797279,-0.13809249703546148,1.0560553218353965,0.2539802870628444,-0.13809249703546148,-0.11665224488806318,0.7259074169551265,-0.5643770990360283,-0.31308432082275484,-1.005443892780752,1.0728192976417978,-0.09530566340648955,-0.7799832529313712,-0.8789201810531422,-0.4257161927970913,-0.8539994760110062,-0.2248062819916635,-1.0311416178800303,-0.010840469228635595,-0.18125720694712386,-0.9798788971454372,0.8326303861028213,3.5258141843000015,-0.9291418506117229,-0.2687463774668492,-0.2687463774668492,0.030850084923550944,0.7795641591048054,-0.07405196659429947,0.07218715987352683,2.7364672632965075,1.10617263797279,-0.4715029980224777,-0.6829914580738592,0.39081896508326114,-0.4257161927970913,1.5804484768707614,2.039170647439996,-0.031820131489916866,-0.20298328683847608,-0.7070610806666029,0.44830289150821834,0.21416484143938402,0.81500648275305,2.677182821571807,0.37150520972870915,0.5239023754686642,3.961959193912149,0.81500648275305,0.39081896508326114,-0.7555558469531406,-0.4715029980224777,-0.13809249703546148,0.3130983356211,-0.4257161927970913,-0.24672702956312,0.6534243244188832,-0.4257161927970913,2.0935117653992443,-0.6114803864575494,-0.09530566340648955,-0.2248062819916635,1.204863382292912,2.7009867150585474,-0.35782711761202085,1.6993479647673133
| 3,069
|
Receptor
| 11
| 28
| 2.877002
| 0.004015
|
Q9NR77,Q567V2,P20645,Q14108,O75381,P57105,Q8WTV0,P39210,Q9UQB8,Q96GI7,A6NIH7
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
0,32,96,41,170,230,13,140,47,114,22
|
22,1951,2615,170,2832,2870,1252,269,96,140,230,497,471,41,1224,2735,32,13,868,114,773,3037,2636,1040,0,2639,3025,47
|
3.5752683604226285,-0.3354046675661042,-0.7799832529313712,1.5804484768707614,-1.0311416178800303,-1.1090446236633436,0.051562445642740554,1.1557719154454555,2.1871309307140887,1.786611952471423,1.2534569702074796,0.7259074169551265,0.7617448151371171,3.0221139040042435,0.07218715987352683,-0.8789201810531422,3.3225382570332864,3.961959193912149,0.33264549575231883,1.9703547683806868,0.4100561090046764,-2.185857809271104,-0.7799832529313712,0.21416484143938402,5.129020836832448,-0.7799832529313712,-1.9325942351876662,2.9325936953118417
| 3,069
|
Ion transmembrane transporter activity
| 35
| 105
| 2.871083
| 0.004091
|
Q9UDW1,O43772,Q93050,Q8TAD4,Q15043,P25705,O15439,P08133,P00846,Q8TDW0,P45880,P21796,P51790,Q9Y277,Q9Y487,Q96QD8,P53985,Q6N075,Q70HW3,Q9Y5K8,P41440,P30825,O75964,Q9H2J7,P16615,Q13423,Q9HD20,P00403,Q9C0H2,P35670,Q6P4Q7,Q9BQT8,Q96ES6,Q9UBX3,O43681
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
132,7,8,135,264,263,137,385,15,415,28,29,414,429,42,444,55,188,61,455,69,73,199,335,458,83,84,85,94,224,232,245,513,253,375
|
2409,1750,137,375,7,2310,1670,2015,199,1332,2377,85,15,1483,1336,2761,783,1203,385,629,1153,3019,1557,2591,1205,2416,2201,458,1524,834,1719,2821,29,785,263,73,2239,224,2320,992,2278,69,28,1020,2989,414,3000,2602,55,2113,2359,2522,1842,2523,2427,2551,83,636,1086,264,756,1110,188,1064,2696,789,232,61,1264,1265,1852,602,135,550,415,2043,8,1773,513,1097,444,3047,587,245,1464,94,2184,335,1778,2470,84,2637,253,132,2055,1174,1122,429,1948,42,455,1047,2308,1949,516
|
-0.6114803864575494,-0.2248062819916635,1.786611952471423,0.9197953633069056,4.1654432084268365,-0.540993539152877,-0.18125720694712386,-0.3803525755016717,1.3963455650807735,0.010049356609845118,-0.5878723702209245,2.3048330176200653,3.7961743788849853,-0.07405196659429947,0.010049356609845118,-0.9291418506117229,0.39081896508326114,0.07218715987352683,0.9024881631846431,0.5426192269625886,0.11317649001570981,-1.871225423943587,-0.11665224488806318,-0.7555558469531406,0.07218715987352683,-0.6114803864575494,-0.4715029980224777,0.7795641591048054,-0.09530566340648955,0.35211425239127736,-0.20298328683847608,-1.005443892780752,3.3741993459998163,0.39081896508326114,1.1721916646896646,2.494694922423651,-0.4945574879422671,1.2855808712415313,-0.540993539152877,0.2341133298905719,-0.5177206708014539,2.519440449494305,3.4455710952889245,0.21416484143938402,-1.6040108138088613,0.8501900582323448,-1.6915054398535807,-0.7555558469531406,2.7009867150585474,-0.4257161927970913,-0.5643770990360283,-0.6829914580738592,-0.2687463774668492,-0.6829914580738592,-0.6114803864575494,-0.7070610806666029,2.3562163638412286,0.5426192269625886,0.1740206722343724,1.1721916646896646,0.42921722537504836,0.15382367299729152,1.458505765790809,0.19413417400581515,-0.8292038872729048,0.39081896508326114,1.2534569702074796,2.629209225162519,0.051562445642740554,0.051562445642740554,-0.2687463774668492,0.5798371070730094,1.801001399719216,0.6534243244188832,0.8501900582323448,-0.3803525755016717,4.1654432084268365,-0.2248062819916635,0.7078884093515075,0.1740206722343724,0.81500648275305,-2.5214717639102737,0.5983391977919877,1.2211160826760208,-0.05289037818638174,2.2135419004040315,-0.44855622173737325,1.0054094308154349,-0.2248062819916635,-0.6352021957308768,2.330594748206502,-0.7799832529313712,1.204863382292912,1.829650134972895,-0.3803525755016717,0.11317649001570981,0.15382367299729152,0.8326303861028213,-0.31308432082275484,2.999894420961043,0.797317893556882,0.21416484143938402,-0.5177206708014539,-0.31308432082275484,0.7078884093515075
| 3,069
|
Intrinsic component of mitochondrial membrane
| 20
| 50
| 2.870026
| 0.004104
|
O43819,Q99595,Q16891,Q15070,O60830,Q5HYI7,Q9BPX6,Q9NX63,Q8IWA4,Q9UG56,Q5XKP0,P50336,O14925,Q9Y2R0,O75431,P57105,O96008,Q9H9P8,Q13505,Q9H4I9
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
627,5,526,399,27,285,159,556,293,574,570,566,563,66,329,230,614,246,117,122
|
563,627,27,329,1331,1601,1408,2377,614,1205,2650,566,2425,230,2427,117,399,1845,526,1577,285,570,789,1652,293,867,1308,1266,1852,916,681,1773,1097,5,159,1510,2668,1196,122,1778,246,2470,2003,1630,556,574,1173,66,805,1399
|
0.6167707540458557,0.5426192269625886,3.475825517493468,1.0054094308154349,0.010049356609845118,-0.13809249703546148,-0.031820131489916866,-0.5878723702209245,0.5612639595076085,0.07218715987352683,-0.8045322091109726,0.6167707540458557,-0.6114803864575494,1.2534569702074796,-0.6114803864575494,1.9564707654985696,0.8851185038122356,-0.2687463774668492,0.6898018853113626,-0.11665224488806318,1.122762779001896,0.6167707540458557,0.39081896508326114,-0.1596272157387103,1.10617263797279,0.33264549575231883,0.030850084923550944,0.051562445642740554,-0.2687463774668492,0.2934721608296331,0.5051128651347058,-0.2248062819916635,0.1740206722343724,4.4424516811688495,1.625384500578365,-0.07405196659429947,-0.8045322091109726,0.09272494003870865,1.9145729797153146,-0.2248062819916635,1.2211160826760208,-0.6352021957308768,-0.35782711761202085,-0.13809249703546148,0.6534243244188832,0.6167707540458557,0.11317649001570981,2.5440562997072673,0.39081896508326114,-0.010840469228635595
| 3,069
|
Mitochondrial protein import
| 16
| 36
| 2.86622
| 0.004154
|
O14925,Q9NX63,Q8N4H5,Q99595,P25705,Q8N4Q1,P62072,O75431,Q5JRX3,Q9NS69,Q13505,Q9Y584,Q3ZCQ8,O60830,P21796,Q10713
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
563,556,130,5,263,548,71,329,369,20,117,153,472,27,29,536
|
563,1283,830,27,2760,329,2150,1670,1601,614,783,1153,2775,1205,2416,29,263,2650,71,536,117,472,369,130,548,1312,5,2338,2583,20,556,1174,1147,1399,153,1865
|
0.6167707540458557,0.030850084923550944,0.35211425239127736,3.475825517493468,-0.9291418506117229,1.0054094308154349,-0.44855622173737325,-0.18125720694712386,-0.13809249703546148,0.5612639595076085,0.39081896508326114,0.11317649001570981,-0.9544453152528625,0.07218715987352683,-0.6114803864575494,3.3741993459998163,1.1721916646896646,-0.8045322091109726,2.5070839778403435,0.6716473552783213,1.9564707654985696,0.7617448151371171,0.9370405358529817,1.829650134972895,0.6534243244188832,0.030850084923550944,4.4424516811688495,-0.540993539152877,-0.731248835894527,3.6241989583234373,0.6534243244188832,0.11317649001570981,0.13354250527191597,-0.010840469228635595,1.6993479647673133,-0.2687463774668492
| 3,069
|
Steroid binding
| 9
| 22
| 2.843816
| 0.004458
|
Q9H4L5,Q14108,P30536,O15173,O15118,P45880,P21796,P04062,O95772
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
304,41,144,328,120,28,29,376,95
|
517,120,328,705,1871,95,376,2199,1483,385,29,1017,2105,144,655,1057,28,41,2183,2296,2828,304
|
0.6898018853113626,1.9145729797153146,1.0054094308154349,0.46731367824728265,-0.29086518455841137,2.2003548878818564,0.9197953633069056,-0.4715029980224777,-0.07405196659429947,0.9024881631846431,3.3741993459998163,0.21416484143938402,-0.4257161927970913,1.7721787798962068,0.5239023754686642,0.19413417400581515,3.4455710952889245,3.0221139040042435,-0.44855622173737325,-0.5177206708014539,-1.005443892780752,1.089524939627866
| 3,069
|
Subsets and Splits
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