term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aminoglycan metabolic process
| 8
| 14
| 3.124751
| 0.00178
|
O43505,P15586,P16278,P04066,P07686,P06865,P54802,Q9NX62
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,1,35,11,46,14,25,94
|
65,1534,1922,11,14,46,1,35,25,1121,107,793,94,214
|
3.2021083972634283,-0.037732006077157064,-0.16899212443771205,5.238210069294953,4.991829849894577,3.8867761966938223,6.058298299026471,4.165756851456292,4.7385298944612435,0.11606410191198446,2.104478107048702,0.26605328440668863,2.416723651268817,0.9885086777190719
| 3,447
|
Abnormal circulating cholesterol concentration
| 8
| 33
| 3.123837
| 0.001785
|
Q15125,Q15392,P01130,P07602,P38571,Q15904,Q9UBM7,P61916
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
68,9,73,15,82,54,86,28
|
3037,2005,73,3180,602,15,2712,82,1258,2587,1262,1552,1264,28,2345,232,612,291,87,68,9,2969,344,54,1572,882,2040,2428,3203,3172,2750,86,2376
|
-0.6676978506562085,-0.19559772347892793,3.0214219227005468,-0.7847504591189078,0.36404879012622693,4.95230803704758,-0.46856343097646624,2.733680073850197,0.06523411656369492,-0.41292781072703233,0.06523411656369492,-0.037732006077157064,0.06523411656369492,4.602257829733616,-0.3032458564235702,0.899727495712953,0.36404879012622693,0.7413917409113739,2.5415711073347276,3.120491344892983,5.327333042658442,-0.6100808230827668,0.6491388771216718,3.613594638576244,-0.037732006077157064,0.21646479318514736,-0.19559772347892793,-0.33047177855621607,-0.7847504591189078,-0.7552547701634187,-0.46856343097646624,2.5768641425022323,-0.3032458564235702
| 3,447
|
Behavior
| 15
| 81
| 3.116103
| 0.001833
|
O75844,P05067,P17900,Q13641,P51790,P01130,Q15334,P07686,Q92542,P04062,P50897,P54802,P10253,P21359,O15118
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
189,66,4,37,70,73,206,46,50,114,21,25,59,220,57
|
2326,1094,3331,57,2329,2004,189,2644,632,2456,1615,569,73,114,970,1031,2333,66,507,1772,46,764,2083,59,1109,4,509,220,672,2466,3381,3213,1858,2015,1255,1468,2656,1258,816,638,676,21,2529,70,1942,25,1867,3409,2103,1044,1412,377,2190,1639,37,729,1347,206,1882,2780,1492,3097,2421,3318,50,2687,229,656,3022,3024,1074,2741,3384,2136,2432,2697,1900,350,2992,3389,2074
|
-0.3032458564235702,0.11606410191198446,-1.057631062572967,3.520478778498601,-0.3032458564235702,-0.19559772347892793,1.0978302599790803,-0.44067800799054646,0.33969505804727207,-0.3578263417200354,-0.06375283048767906,0.3883074039088583,3.0214219227005468,1.952786157251336,0.16647131175699767,0.14131998091565823,-0.3032458564235702,3.185852181395418,0.43654311105882554,-0.11613860568977677,3.8867761966938223,0.26605328440668863,-0.22232443406475605,3.426283702043037,0.11606410191198446,5.796784418092093,0.43654311105882554,0.944268201707387,0.3152452291356413,-0.3578263417200354,-1.3451913690083444,-0.8144047886641401,-0.14250621643165773,-0.19559772347892793,0.06523411656369492,-0.011824157758994824,-0.44067800799054646,0.06523411656369492,0.24130912809996094,0.33969505804727207,0.3152452291356413,4.832688203866245,-0.38531114273962846,3.0545841549970008,-0.16899212443771205,4.7385298944612435,-0.14250621643165773,-1.7183704220896816,-0.22232443406475605,0.14131998091565823,0.013971984461395193,0.6025084155120215,-0.2491737041569007,-0.06375283048767906,4.136820106166587,0.290698308478738,0.03965766766041974,1.032454143437075,-0.14250621643165773,-0.49658581124515616,-0.011824157758994824,-0.6967305875166148,-0.33047177855621607,-0.9957915972367293,3.736124836573613,-0.44067800799054646,0.9220357095144189,0.33969505804727207,-0.6388152651515875,-0.6388152651515875,0.14131998091565823,-0.46856343097646624,-1.3451913690083444,-0.22232443406475605,-0.33047177855621607,-0.44067800799054646,-0.14250621643165773,0.6491388771216718,-0.6100808230827668,-1.3781294605421666,-0.19559772347892793
| 3,447
|
Carbohydrate catabolic process
| 6
| 53
| 3.112833
| 0.001853
|
P05067,P16278,P17900,P07686,Q14108,P10253
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,35,4,46,26,59
|
1607,2004,1770,2646,2459,2516,1703,2333,66,2647,602,1772,46,1706,706,2335,59,1105,1709,35,489,4,1464,2579,981,1716,2269,1255,2174,1552,1180,2766,314,280,1943,3010,2477,2531,1871,2667,2871,1273,2596,377,26,2827,1363,75,1143,698,2797,1149,420
|
-0.06375283048767906,-0.19559772347892793,-0.11613860568977677,-0.44067800799054646,-0.3578263417200354,-0.38531114273962846,-0.08988792448924106,-0.3032458564235702,3.185852181395418,-0.44067800799054646,0.36404879012622693,-0.11613860568977677,3.8867761966938223,-0.08988792448924106,0.290698308478738,-0.3032458564235702,3.426283702043037,0.11606410191198446,-0.08988792448924106,4.165756851456292,0.460522082895191,5.796784418092093,-0.011824157758994824,-0.41292781072703233,0.16647131175699767,-0.08988792448924106,-0.2761470099076228,0.06523411656369492,-0.2491737041569007,-0.037732006077157064,0.09070253409564899,-0.49658581124515616,0.6954312126789955,0.764249500072063,-0.16899212443771205,-0.6388152651515875,-0.3578263417200354,-0.38531114273962846,-0.14250621643165773,-0.44067800799054646,-0.5530485515520936,0.06523411656369492,-0.41292781072703233,0.6025084155120215,4.7385298944612435,-0.5247469164830378,0.03965766766041974,3.0047879739765255,0.11606410191198446,0.3152452291356413,-0.49658581124515616,0.11606410191198446,0.5555333123030265
| 3,447
|
Neuron death
| 20
| 82
| 3.106903
| 0.001891
|
P51858,Q15392,P50897,Q01105,Q9UMX5,Q9NR28,Q92542,Q99720,P10909,P09601,P07196,P05067,Q14790,P21359,O14786,Q13315,P04062,Q15375,Q15058,P48681
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
376,9,21,152,172,174,50,51,58,311,310,66,205,220,99,362,114,119,379,249
|
99,968,2644,632,2862,387,114,1031,1703,2333,66,904,1772,310,905,706,311,2084,58,2086,1109,220,3342,1035,3213,1937,2656,1259,1782,1260,249,2018,916,21,2529,376,774,1265,2185,1944,1185,1557,778,2768,1561,2103,152,2278,1044,2535,781,2919,362,518,1639,546,205,379,1735,119,9,1200,581,1425,50,2365,1748,2043,2784,656,3024,51,2432,698,174,2799,1447,1306,3352,172,959,1997
|
2.308023112336245,0.16647131175699767,-0.44067800799054646,0.33969505804727207,-0.5530485515520936,0.5790643592485345,1.952786157251336,0.14131998091565823,-0.08988792448924106,-0.3032458564235702,3.185852181395418,0.19151921531853922,-0.11613860568977677,0.6954312126789955,0.19151921531853922,0.290698308478738,0.6954312126789955,-0.22232443406475605,3.4892019402118737,-0.22232443406475605,0.11606410191198446,0.944268201707387,-1.0888207132458592,0.14131998091565823,-0.8144047886641401,-0.16899212443771205,-0.44067800799054646,0.06523411656369492,-0.11613860568977677,0.06523411656369492,0.8548811891149231,-0.19559772347892793,0.19151921531853922,4.832688203866245,-0.38531114273962846,0.6025084155120215,0.26605328440668863,0.06523411656369492,-0.2491737041569007,-0.16899212443771205,0.09070253409564899,-0.037732006077157064,0.26605328440668863,-0.49658581124515616,-0.037732006077157064,-0.22232443406475605,1.4567344646526146,-0.2761470099076228,0.14131998091565823,-0.38531114273962846,0.26605328440668863,-0.5814925595785796,0.625866314583955,0.43654311105882554,-0.06375283048767906,0.412471861925284,1.032454143437075,0.6025084155120215,-0.08988792448924106,1.8757230653380457,5.327333042658442,0.09070253409564899,0.3883074039088583,0.013971984461395193,3.736124836573613,-0.3032458564235702,-0.08988792448924106,-0.19559772347892793,-0.49658581124515616,0.33969505804727207,-0.6388152651515875,3.6750880080144026,-0.33047177855621607,0.3152452291356413,1.2266908335657118,-0.49658581124515616,0.013971984461395193,0.06523411656369492,-1.1201939880656602,1.247929148925315,0.19151921531853922,-0.16899212443771205
| 3,447
|
Ficolin 1 rich granule
| 20
| 88
| 3.097517
| 0.001951
|
P15586,Q93050,P67870,Q9Y315,Q8WVQ1,P16278,P14174,Q5T4S7,P11279,Q13510,P42785,P20618,O75874,P10253,P17980,Q14019,P35237,Q13442,Q6IAA8,P17858
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,257,274,420,412,35,404,432,41,43,49,426,55,59,444,452,478,227,238,489
|
802,2149,2151,1525,1026,667,55,1455,1102,705,2516,970,602,1772,668,1168,905,1104,1461,2335,1926,59,2391,41,2161,2577,1462,1170,404,1709,1928,1,1710,35,489,860,444,1463,1464,426,1246,1775,1853,1933,2466,478,981,1857,2269,982,49,1940,2343,1721,1941,2275,1867,1944,1730,3012,274,2478,3241,3052,1792,227,43,452,730,1346,1485,432,521,238,1058,881,412,257,622,1434,1588,2898,2146,1522,3032,420,2073,1382
|
0.24130912809996094,-0.2491737041569007,-0.2491737041569007,-0.037732006077157064,0.14131998091565823,0.3152452291356413,3.5826739461700328,-0.011824157758994824,0.11606410191198446,0.290698308478738,-0.38531114273962846,0.16647131175699767,0.36404879012622693,-0.11613860568977677,0.3152452291356413,0.09070253409564899,0.19151921531853922,0.11606410191198446,-0.011824157758994824,-0.3032458564235702,-0.16899212443771205,3.426283702043037,-0.33047177855621607,4.005368888045156,-0.2491737041569007,-0.41292781072703233,-0.011824157758994824,0.09070253409564899,0.5555333123030265,-0.08988792448924106,-0.16899212443771205,6.058298299026471,-0.08988792448924106,4.165756851456292,0.460522082895191,0.21646479318514736,0.5082068465574456,-0.011824157758994824,-0.011824157758994824,0.5319144280730378,0.06523411656369492,-0.11613860568977677,-0.14250621643165773,-0.16899212443771205,-0.3578263417200354,0.48440969406177936,0.16647131175699767,-0.14250621643165773,-0.2761470099076228,0.16647131175699767,3.7816081165133633,-0.16899212443771205,-0.3032458564235702,-0.08988792448924106,-0.16899212443771205,-0.2761470099076228,-0.14250621643165773,-0.16899212443771205,-0.08988792448924106,-0.6388152651515875,0.7870265918459427,-0.3578263417200354,-0.8442200027409706,-0.6676978506562085,-0.11613860568977677,0.9220357095144189,3.9610928617452967,0.5082068465574456,0.290698308478738,0.03965766766041974,-0.011824157758994824,0.5319144280730378,0.43654311105882554,0.8773428842135269,0.14131998091565823,0.21646479318514736,0.5555333123030265,0.8323417145063771,0.36404879012622693,0.013971984461395193,-0.037732006077157064,-0.5530485515520936,-0.22232443406475605,-0.011824157758994824,-0.6388152651515875,0.5555333123030265,-0.19559772347892793,0.03965766766041974
| 3,447
|
Host cell receptor for virus entry
| 9
| 17
| 3.096657
| 0.001957
|
P35613,P78310,P11279,P01130,P02786,Q9Y624,Q14108,Q8WTV0,O15118
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
160,136,41,73,52,121,26,62,57
|
57,569,73,52,507,1032,1239,1926,41,1618,178,160,136,26,343,62,121
|
3.520478778498601,0.3883074039088583,3.0214219227005468,3.6443989474477476,0.43654311105882554,0.14131998091565823,0.06523411656369492,-0.16899212443771205,4.005368888045156,-0.06375283048767906,1.162570531532433,1.3739783978655824,1.6193233192302938,4.7385298944612435,0.6491388771216718,3.3469394788706537,1.8368772029414835
| 3,447
|
Exogenous protein binding
| 9
| 17
| 3.096657
| 0.001957
|
P35613,P78310,P11279,P01130,P02786,Q9Y624,Q14108,Q8WTV0,O15118
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
160,136,41,73,52,121,26,62,57
|
57,569,73,52,507,1032,1239,1926,41,1618,178,160,136,26,343,62,121
|
3.520478778498601,0.3883074039088583,3.0214219227005468,3.6443989474477476,0.43654311105882554,0.14131998091565823,0.06523411656369492,-0.16899212443771205,4.005368888045156,-0.06375283048767906,1.162570531532433,1.3739783978655824,1.6193233192302938,4.7385298944612435,0.6491388771216718,3.3469394788706537,1.8368772029414835
| 3,447
|
Taxis
| 24
| 74
| 3.093784
| 0.001976
|
P42892,P78310,Q92859,P33527,Q13740,P35613,Q00013,P14174,Q13641,P29317,P26583,P11233,Q07021,P05067,O00429,O94813,Q9NUQ9,Q92538,Q7L576,Q9UIW2,O14786,P55011,Q04721,Q15375
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
5,136,23,153,154,160,162,404,37,178,297,424,191,66,323,84,486,483,223,225,99,491,493,119
|
1094,323,99,804,857,84,1847,1616,2460,66,488,1104,424,404,860,2580,3004,297,1249,671,2466,178,1250,3213,913,153,160,540,5,1334,3087,3088,3044,2181,1406,491,1472,1944,1730,136,1633,162,2103,2346,493,1189,191,37,154,1279,2284,119,1485,2679,994,2727,223,941,791,739,2130,483,23,1212,3106,2221,2223,588,3107,2136,1982,486,225,962
|
0.11606410191198446,0.6723269112207332,2.308023112336245,0.24130912809996094,0.21646479318514736,2.6294966021683392,-0.14250621643165773,-0.06375283048767906,-0.3578263417200354,3.185852181395418,0.460522082895191,0.11606410191198446,0.5319144280730378,0.5555333123030265,0.21646479318514736,-0.41292781072703233,-0.6388152651515875,0.7184525652536403,0.06523411656369492,0.3152452291356413,-0.3578263417200354,1.162570531532433,0.06523411656369492,-0.8144047886641401,0.19151921531853922,1.4154814144632912,1.3739783978655824,0.412471861925284,5.626549900164905,0.03965766766041974,-0.6967305875166148,-0.6967305875166148,-0.6676978506562085,-0.2491737041569007,0.013971984461395193,0.460522082895191,-0.011824157758994824,-0.16899212443771205,-0.08988792448924106,1.6193233192302938,-0.06375283048767906,1.3322214270954764,-0.22232443406475605,-0.3032458564235702,0.460522082895191,0.09070253409564899,1.0978302599790803,4.136820106166587,1.4154814144632912,0.06523411656369492,-0.2761470099076228,1.8757230653380457,-0.011824157758994824,-0.44067800799054646,0.16647131175699767,-0.46856343097646624,0.944268201707387,0.19151921531853922,0.26605328440668863,0.290698308478738,-0.22232443406475605,0.48440969406177936,4.792456598943272,0.09070253409564899,-0.6967305875166148,-0.2491737041569007,-0.2491737041569007,0.3883074039088583,-0.6967305875166148,-0.22232443406475605,-0.16899212443771205,0.48440969406177936,0.944268201707387,0.19151921531853922
| 3,447
|
Glycoside hydrolase superfamily [IPR017853]
| 9
| 15
| 3.091824
| 0.001989
|
P16278,P04066,P06280,P07686,P06865,P04062,Q9BTY2,P54802,P10253
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
35,11,12,46,14,114,24,25,59
|
3281,114,11,12,14,46,161,59,35,981,25,2278,2599,24,2558
|
-0.9346541779980903,1.952786157251336,5.238210069294953,5.096383797522485,4.991829849894577,3.8867761966938223,1.3531319100008414,3.426283702043037,4.165756851456292,0.16647131175699767,4.7385298944612435,-0.2761470099076228,-0.41292781072703233,4.752042300962526,-0.38531114273962846
| 3,447
|
Golgi apparatus
| 49
| 191
| 3.087896
| 0.002016
|
A4D1U4,Q93050,Q8NEW0,Q9HB40,Q86Y82,Q9GZM5,O43617,Q5VW38,O43493,P50897,O75071,Q92859,O60476,P54646,Q9HD45,P11717,Q8IYS2,P16278,Q8IZA0,Q9BV57,Q5KU26,Q9UID3,Q99523,P29317,P98194,Q9C005,Q15012,Q9Y678,Q92896,P05067,O75955,O00461,P04439,Q8IXU6,P55327,Q92520,Q6ZRP7,Q9BRK5,O95456,Q9H2V7,Q9NX62,Q02818,O15260,P80303,Q8NC54,Q10471,Q9UEU0,O43760,Q6IAA8
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
128,257,130,3,256,269,261,144,18,21,22,23,149,280,156,31,159,35,36,166,38,307,45,178,298,320,56,188,63,66,196,71,72,74,211,213,217,89,215,93,94,95,98,101,102,232,105,230,238
|
2449,128,1838,2511,802,71,2806,3419,1527,1098,702,3178,98,594,3257,2950,2327,18,261,230,149,374,2904,1698,1535,595,22,1840,2389,1611,196,3323,2390,761,215,72,66,3182,488,311,2085,2158,31,35,425,1171,2268,1711,710,1712,178,2168,2584,861,1716,1113,358,1781,862,638,479,1863,1551,21,1552,642,3046,1941,1117,280,211,1628,3284,1947,101,3123,2666,298,1411,95,1189,3191,428,232,1047,1275,682,2825,1278,1127,2827,2486,614,1128,56,430,1567,38,2776,1569,2115,144,651,1352,238,2730,2605,1959,2732,1419,482,217,2548,2292,881,2835,3099,256,1805,2208,74,583,159,36,789,395,1650,102,693,130,1888,943,792,2613,2423,412,213,483,23,63,2888,257,944,1656,2889,1140,1364,1504,1011,45,1663,1973,2222,89,2936,166,1979,2694,320,269,2499,1078,93,2792,2059,3328,3143,1673,952,3,1756,156,1016,2372,1595,2629,2897,1677,400,94,751,1989,531,105,3400,2945,307,2243,2803,1381,188
|
-0.3578263417200354,1.6992145766721194,-0.14250621643165773,-0.38531114273962846,0.24130912809996094,3.0380205848750497,-0.5247469164830378,-1.8599003564047882,-0.037732006077157064,0.11606410191198446,0.290698308478738,-0.7847504591189078,2.326250857937109,0.36404879012622693,-0.9043423207096438,-0.6100808230827668,-0.3032458564235702,4.925863408400397,0.80972375426467,0.899727495712953,1.477268471012952,0.6025084155120215,-0.5814925595785796,-0.08988792448924106,-0.037732006077157064,0.36404879012622693,4.805887326746089,-0.14250621643165773,-0.33047177855621607,-0.06375283048767906,1.054317838750862,-1.0266222601373636,-0.33047177855621607,0.26605328440668863,0.9664256387623936,3.0380205848750497,3.185852181395418,-0.7847504591189078,0.460522082895191,0.6954312126789955,-0.22232443406475605,-0.2491737041569007,4.393795198319631,4.165756851456292,0.5319144280730378,0.09070253409564899,-0.2761470099076228,-0.08988792448924106,0.290698308478738,-0.08988792448924106,1.162570531532433,-0.2491737041569007,-0.41292781072703233,0.21646479318514736,-0.08988792448924106,0.11606410191198446,0.625866314583955,-0.11613860568977677,0.21646479318514736,0.33969505804727207,0.48440969406177936,-0.14250621643165773,-0.037732006077157064,4.832688203866245,-0.037732006077157064,0.33969505804727207,-0.6676978506562085,-0.16899212443771205,0.11606410191198446,0.764249500072063,0.9885086777190719,-0.06375283048767906,-0.9346541779980903,-0.16899212443771205,2.2530683333705355,-0.7259155280154393,-0.44067800799054646,0.7184525652536403,0.013971984461395193,2.3625723141377883,0.09070253409564899,-0.7847504591189078,0.5319144280730378,0.899727495712953,0.14131998091565823,0.06523411656369492,0.3152452291356413,-0.5247469164830378,0.06523411656369492,0.11606410191198446,-0.5247469164830378,-0.3578263417200354,0.36404879012622693,0.11606410191198446,3.55163571681315,0.5319144280730378,-0.037732006077157064,4.136820106166587,-0.49658581124515616,-0.037732006077157064,-0.22232443406475605,1.5181538302974797,0.33969505804727207,0.03965766766041974,0.8773428842135269,-0.46856343097646624,-0.41292781072703233,-0.16899212443771205,-0.46856343097646624,0.013971984461395193,0.48440969406177936,0.9664256387623936,-0.38531114273962846,-0.2761470099076228,0.21646479318514736,-0.5247469164830378,-0.6967305875166148,0.8323417145063771,-0.11613860568977677,-0.2491737041569007,3.0047879739765255,0.3883074039088583,1.3947613988096557,4.151300777268037,0.26605328440668863,0.5790643592485345,-0.06375283048767906,2.2530683333705355,0.3152452291356413,1.6793270618899536,-0.14250621643165773,0.19151921531853922,0.26605328440668863,-0.41292781072703233,-0.33047177855621607,0.5555333123030265,0.9885086777190719,0.48440969406177936,4.792456598943272,3.3469394788706537,-0.5530485515520936,0.8323417145063771,0.19151921531853922,-0.06375283048767906,-0.5530485515520936,0.11606410191198446,0.03965766766041974,-0.011824157758994824,0.16647131175699767,3.9016924241886017,-0.06375283048767906,-0.16899212443771205,-0.2491737041569007,2.5415711073347276,-0.5814925595785796,1.311246434423248,-0.16899212443771205,-0.44067800799054646,0.6954312126789955,0.80972375426467,-0.3578263417200354,0.14131998091565823,2.4346869816913186,-0.49658581124515616,-0.19559772347892793,-1.0266222601373636,-0.7259155280154393,-0.06375283048767906,0.19151921531853922,5.856849705901865,-0.08988792448924106,1.4154814144632912,0.16647131175699767,-0.3032458564235702,-0.037732006077157064,-0.41292781072703233,-0.5530485515520936,-0.06375283048767906,0.5790643592485345,2.416723651268817,0.290698308478738,-0.16899212443771205,0.43654311105882554,2.179150607376429,-1.4781383235442953,-0.5814925595785796,0.7184525652536403,-0.2491737041569007,-0.49658581124515616,0.03965766766041974,1.1194802025914279
| 3,447
|
Cellular ion homeostasis
| 21
| 88
| 3.078349
| 0.002082
|
Q93050,Q8NEW0,P54289,O75503,P50897,Q92544,P07686,Q7L0J3,P98194,P02786,Q15904,P05026,Q9HD20,P09601,P05067,P51790,Q15334,Q96PU5,P54709,O14745,P0DP25
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
257,130,131,8,21,170,46,48,298,52,54,183,187,311,66,70,206,349,221,338,104
|
2511,897,338,1696,667,1162,3408,8,1236,2259,632,2952,2457,52,1459,183,66,3212,46,488,3116,1104,311,1708,104,2651,707,1394,811,2519,2520,1244,908,1395,1173,1249,978,671,2466,1714,1037,1258,21,641,2474,70,131,221,491,1338,517,3049,298,2103,1412,2485,3192,206,54,2828,3162,735,48,2838,882,791,2037,130,1003,170,257,1809,744,1810,349,3167,840,187,562,1447,958,533,1307,384,801,3176,3372,1912
|
-0.38531114273962846,0.19151921531853922,0.6491388771216718,-0.08988792448924106,0.3152452291356413,0.09070253409564899,-1.6834681362086772,5.390468925074161,0.06523411656369492,-0.2761470099076228,0.33969505804727207,-0.6100808230827668,-0.3578263417200354,3.6443989474477476,-0.011824157758994824,1.1194802025914279,3.185852181395418,-0.8144047886641401,3.8867761966938223,0.460522082895191,-0.7259155280154393,0.11606410191198446,0.6954312126789955,-0.08988792448924106,2.179150607376429,-0.44067800799054646,0.290698308478738,0.013971984461395193,0.24130912809996094,-0.38531114273962846,-0.38531114273962846,0.06523411656369492,0.19151921531853922,0.013971984461395193,0.09070253409564899,0.06523411656369492,0.16647131175699767,0.3152452291356413,-0.3578263417200354,-0.08988792448924106,0.14131998091565823,0.06523411656369492,4.832688203866245,0.33969505804727207,-0.3578263417200354,3.0545841549970008,1.6593829626856886,0.944268201707387,0.460522082895191,0.03965766766041974,0.43654311105882554,-0.6676978506562085,0.7184525652536403,-0.22232443406475605,0.013971984461395193,-0.3578263417200354,-0.7847504591189078,1.032454143437075,3.613594638576244,-0.5247469164830378,-0.7552547701634187,0.290698308478738,3.841866850895795,-0.5247469164830378,0.21646479318514736,0.26605328440668863,-0.19559772347892793,1.6793270618899536,0.16647131175699767,1.247929148925315,0.8323417145063771,-0.11613860568977677,0.290698308478738,-0.11613860568977677,0.6491388771216718,-0.7552547701634187,0.24130912809996094,1.1194802025914279,0.412471861925284,0.013971984461395193,0.19151921531853922,0.43654311105882554,0.06523411656369492,0.6025084155120215,0.26605328440668863,-0.7552547701634187,-1.2799168876410205,-0.14250621643165773
| 3,447
|
Immunoglobulin-like domain superfamily [IPR036179]
| 9
| 15
| 3.073333
| 0.002117
|
P35613,P04439,P78310,Q9BY67,P10321,Q92859,Q9Y624,Q13740,P43121
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
160,72,136,175,83,23,121,154,126
|
2257,72,83,2085,160,126,136,194,725,154,2130,23,175,1520,121
|
-0.2761470099076228,3.0380205848750497,2.699110242674545,-0.22232443406475605,1.3739783978655824,1.7388215146356225,1.6193233192302938,1.0761096734158762,0.290698308478738,1.4154814144632912,-0.22232443406475605,4.792456598943272,1.1840120855874656,-0.011824157758994824,1.8368772029414835
| 3,447
|
Immunoglobulin-like domain [IPR007110]
| 9
| 15
| 3.073333
| 0.002117
|
P35613,P04439,P78310,Q9BY67,P10321,Q92859,Q9Y624,Q13740,P43121
|
Sequence
|
InterPro Domain
|
interpro_domain
|
160,72,136,175,83,23,121,154,126
|
2257,72,83,2085,160,126,136,194,725,154,2130,23,175,1520,121
|
-0.2761470099076228,3.0380205848750497,2.699110242674545,-0.22232443406475605,1.3739783978655824,1.7388215146356225,1.6193233192302938,1.0761096734158762,0.290698308478738,1.4154814144632912,-0.22232443406475605,4.792456598943272,1.1840120855874656,-0.011824157758994824,1.8368772029414835
| 3,447
|
Biological process involved in interaction with host
| 12
| 59
| 3.071597
| 0.002129
|
P35613,P08195,Q9Y624,O14786,P78310,P11279,P01130,P02786,Q9BTY2,O15118,Q14108,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,161,121,99,136,41,73,52,24,57,26,62
|
2450,1450,99,57,1608,1768,1102,569,73,52,507,1032,1166,161,1239,1926,41,3416,1618,1542,3296,3342,178,2525,160,2173,2180,641,136,1343,925,1795,2484,26,1875,343,1737,940,3402,1966,62,3060,2620,1069,2132,1071,1895,3358,24,435,797,2630,2375,3109,754,1227,285,502,121
|
-0.3578263417200354,-0.011824157758994824,2.308023112336245,3.520478778498601,-0.06375283048767906,-0.11613860568977677,0.11606410191198446,0.3883074039088583,3.0214219227005468,3.6443989474477476,0.43654311105882554,0.14131998091565823,0.09070253409564899,1.3531319100008414,0.06523411656369492,-0.16899212443771205,4.005368888045156,-1.8242310197178253,-0.06375283048767906,-0.037732006077157064,-0.9651364301489054,-1.0888207132458592,1.162570531532433,-0.38531114273962846,1.3739783978655824,-0.2491737041569007,-0.2491737041569007,0.33969505804727207,1.6193233192302938,0.03965766766041974,0.19151921531853922,-0.11613860568977677,-0.3578263417200354,4.7385298944612435,-0.14250621643165773,0.6491388771216718,-0.08988792448924106,0.19151921531853922,-1.511870415093519,-0.16899212443771205,3.3469394788706537,-0.6676978506562085,-0.41292781072703233,0.14131998091565823,-0.22232443406475605,0.14131998091565823,-0.14250621643165773,-1.1835028638774374,4.752042300962526,0.5319144280730378,0.26605328440668863,-0.41292781072703233,-0.3032458564235702,-0.6967305875166148,0.290698308478738,0.09070253409564899,0.764249500072063,0.460522082895191,1.8368772029414835
| 3,447
|
Ascites
| 9
| 27
| 3.058463
| 0.002225
|
P10644,Q13510,Q99519,P38571,P04062,Q14739,O15118,Q14108,P61916
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
193,43,75,82,114,87,57,26,28
|
57,3258,2077,473,1457,114,193,1107,2814,3342,82,2659,28,1187,2769,1410,222,2278,782,43,26,87,931,655,75,1903,1092
|
3.520478778498601,-0.9043423207096438,-0.22232443406475605,0.48440969406177936,-0.011824157758994824,1.952786157251336,1.0761096734158762,0.11606410191198446,-0.5247469164830378,-1.0888207132458592,2.733680073850197,-0.44067800799054646,4.602257829733616,0.09070253409564899,-0.49658581124515616,0.013971984461395193,0.944268201707387,-0.2761470099076228,0.26605328440668863,3.9610928617452967,4.7385298944612435,2.5415711073347276,0.19151921531853922,0.33969505804727207,3.0047879739765255,-0.14250621643165773,0.14131998091565823
| 3,447
|
Basolateral plasma membrane
| 16
| 45
| 3.050093
| 0.002288
|
P35613,P08195,O75955,P78310,P11166,P01130,P30825,Q6P4Q7,P19022,Q9BY67,P41440,P02786,P05026,P33527,Q07954,P54709
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
160,161,196,136,263,73,140,365,110,175,359,52,183,153,60,221
|
2075,1526,196,2155,569,73,52,1616,1459,183,2462,161,905,263,2159,1618,708,1710,110,908,1173,711,140,3213,153,1937,160,359,1942,221,491,1786,1723,136,1734,60,1949,408,1279,928,549,365,3166,175,1912
|
-0.22232443406475605,-0.037732006077157064,1.054317838750862,-0.2491737041569007,0.3883074039088583,3.0214219227005468,3.6443989474477476,-0.06375283048767906,-0.011824157758994824,1.1194802025914279,-0.3578263417200354,1.3531319100008414,0.19151921531853922,0.80972375426467,-0.2491737041569007,-0.06375283048767906,0.290698308478738,-0.08988792448924106,2.0100448717400776,0.19151921531853922,0.09070253409564899,0.290698308478738,1.5790322112008415,-0.8144047886641401,1.4154814144632912,-0.16899212443771205,1.3739783978655824,0.625866314583955,-0.16899212443771205,0.944268201707387,0.460522082895191,-0.11613860568977677,-0.08988792448924106,1.6193233192302938,-0.08988792448924106,3.362871077444676,-0.16899212443771205,0.5555333123030265,0.06523411656369492,0.19151921531853922,0.412471861925284,0.625866314583955,-0.7552547701634187,1.1840120855874656,-0.14250621643165773
| 3,447
|
Membrane microdomain
| 27
| 72
| 3.049902
| 0.002289
|
Q86Y82,Q9UJZ1,P78310,P11166,O14773,P05556,P50897,O00560,P35613,Q12959,P20339,Q9Y2Q5,P27105,P05026,O15118,Q8WTV0,P09601,P05067,P10644,O75955,Q14790,O14745,P30154,P19022,P41440,Q6IAA8,P07948
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
256,533,136,263,10,507,21,151,160,408,539,322,53,183,57,62,311,66,193,196,205,338,477,110,359,238,488
|
2702,151,338,10,2381,57,196,1844,569,2459,2461,1459,183,66,2334,507,2264,2462,1167,488,1034,706,311,193,263,1774,708,2519,2520,1109,110,2579,908,539,3261,3342,1173,2863,53,1249,2466,477,1546,1937,2711,160,1177,359,2656,1334,2018,1784,21,2662,3012,136,2104,781,408,1274,1793,549,205,238,256,62,3024,795,533,2322,847,322
|
-0.46856343097646624,1.4567344646526146,0.6491388771216718,5.276511437873593,-0.33047177855621607,3.520478778498601,1.054317838750862,-0.14250621643165773,0.3883074039088583,-0.3578263417200354,-0.3578263417200354,-0.011824157758994824,1.1194802025914279,3.185852181395418,-0.3032458564235702,0.43654311105882554,-0.2761470099076228,-0.3578263417200354,0.09070253409564899,0.460522082895191,0.14131998091565823,0.290698308478738,0.6954312126789955,1.0761096734158762,0.80972375426467,-0.11613860568977677,0.290698308478738,-0.38531114273962846,-0.38531114273962846,0.11606410191198446,2.0100448717400776,-0.41292781072703233,0.19151921531853922,0.412471861925284,-0.9043423207096438,-1.0888207132458592,0.09070253409564899,-0.5530485515520936,3.6443989474477476,0.06523411656369492,-0.3578263417200354,0.48440969406177936,-0.037732006077157064,-0.16899212443771205,-0.46856343097646624,1.3739783978655824,0.09070253409564899,0.625866314583955,-0.44067800799054646,0.03965766766041974,-0.19559772347892793,-0.11613860568977677,4.832688203866245,-0.44067800799054646,-0.6388152651515875,1.6193233192302938,-0.22232443406475605,0.26605328440668863,0.5555333123030265,0.06523411656369492,-0.11613860568977677,0.412471861925284,1.032454143437075,0.8773428842135269,0.8323417145063771,3.3469394788706537,-0.6388152651515875,0.26605328440668863,0.43654311105882554,-0.2761470099076228,0.24130912809996094,0.6954312126789955
| 3,447
|
Tertiary granule
| 12
| 44
| 3.048354
| 0.002301
|
Q93050,Q08722,Q92820,P11279,Q13510,P42785,O15400,Q6IAA8,P27105,O75874,P10253,Q7L576
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
257,194,42,41,43,49,210,238,53,55,59,223
|
1837,2075,210,667,55,1455,2516,970,1461,2335,59,41,1710,860,53,478,2269,49,1941,819,2662,1944,1730,3012,194,3241,43,2191,2543,994,432,521,238,223,832,412,42,257,3136,1813,2234,2146,322,1382
|
-0.14250621643165773,-0.22232443406475605,0.9885086777190719,0.3152452291356413,3.5826739461700328,-0.011824157758994824,-0.38531114273962846,0.16647131175699767,-0.011824157758994824,-0.3032458564235702,3.426283702043037,4.005368888045156,-0.08988792448924106,0.21646479318514736,3.6443989474477476,0.48440969406177936,-0.2761470099076228,3.7816081165133633,-0.16899212443771205,0.24130912809996094,-0.44067800799054646,-0.16899212443771205,-0.08988792448924106,-0.6388152651515875,1.0761096734158762,-0.8442200027409706,3.9610928617452967,-0.2491737041569007,-0.38531114273962846,0.16647131175699767,0.5319144280730378,0.43654311105882554,0.8773428842135269,0.944268201707387,0.24130912809996094,0.5555333123030265,4.005368888045156,0.8323417145063771,-0.7259155280154393,-0.11613860568977677,-0.2491737041569007,-0.22232443406475605,0.6954312126789955,0.03965766766041974
| 3,447
|
Lysosomal transport
| 13
| 50
| 3.046632
| 0.002314
|
P10909,Q9UID3,P11279,Q99523,P20645,Q8WUH2,P07602,P46934,O15118,Q14108,Q07954,Q9UQN3,P11717
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
58,307,41,45,142,218,15,184,57,26,60,285,31
|
2511,897,2382,1527,57,1695,1768,15,58,2391,41,31,142,184,641,481,2275,60,26,1569,3193,1055,1057,2835,1805,218,3060,744,1657,1069,2044,656,45,3358,2694,1509,839,2308,797,2750,2630,3109,2320,3345,307,754,321,285,2856,502
|
-0.38531114273962846,0.19151921531853922,-0.33047177855621607,-0.037732006077157064,3.520478778498601,-0.08988792448924106,-0.11613860568977677,4.95230803704758,3.4892019402118737,-0.33047177855621607,4.005368888045156,4.393795198319631,1.5587987614920094,1.1194802025914279,0.33969505804727207,0.48440969406177936,-0.2761470099076228,3.362871077444676,4.7385298944612435,-0.037732006077157064,-0.7847504591189078,0.14131998091565823,0.14131998091565823,-0.5247469164830378,-0.11613860568977677,0.9664256387623936,-0.6676978506562085,0.290698308478738,-0.06375283048767906,0.14131998091565823,-0.19559772347892793,0.33969505804727207,3.9016924241886017,-1.1835028638774374,-0.44067800799054646,-0.011824157758994824,0.24130912809996094,-0.2761470099076228,0.26605328440668863,-0.46856343097646624,-0.41292781072703233,-0.6967305875166148,-0.2761470099076228,-1.0888207132458592,0.7184525652536403,0.290698308478738,0.6954312126789955,0.764249500072063,-0.5247469164830378,0.460522082895191
| 3,447
|
Abnormal vertebral morphology
| 19
| 116
| 3.039409
| 0.00237
|
P15586,P04066,P54802,Q14108,O00754,P16278,P10619,O75874,Q32P28,P10644,Q15125,Q99519,P51798,Q9UBM7,Q14739,Q5SZK8,Q9Y619,P48735,P04062
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,11,25,26,30,35,47,55,185,193,68,75,209,86,87,92,103,111,114
|
1155,1688,30,1156,1691,758,2860,2384,505,1162,2257,2389,2907,2005,55,2952,387,1324,1458,114,11,1166,47,193,3248,1,35,2518,3152,1543,2393,220,3004,1711,2864,2583,2584,1332,2467,3042,540,358,111,2765,1784,209,3411,25,1264,1472,2100,1187,2664,2769,2770,2345,1475,493,2028,450,612,2403,3301,26,991,87,683,930,68,2286,1484,2969,3396,185,1956,3343,92,433,828,2605,2925,2120,1290,1206,1573,552,301,1427,412,347,283,1811,1071,793,3349,1505,75,2220,3275,469,3385,3414,1220,86,891,2562,1019,3352,1307,2855,1993,1994,962,3148,503,103
|
0.09070253409564899,-0.08988792448924106,4.49169826573745,0.09070253409564899,-0.08988792448924106,0.26605328440668863,-0.5530485515520936,-0.33047177855621607,0.43654311105882554,0.09070253409564899,-0.2761470099076228,-0.33047177855621607,-0.5814925595785796,-0.19559772347892793,3.5826739461700328,-0.6100808230827668,0.5790643592485345,0.03965766766041974,-0.011824157758994824,1.952786157251336,5.238210069294953,0.09070253409564899,3.8568635354262555,1.0761096734158762,-0.8741983970490654,6.058298299026471,4.165756851456292,-0.38531114273962846,-0.7552547701634187,-0.037732006077157064,-0.33047177855621607,0.944268201707387,-0.6388152651515875,-0.08988792448924106,-0.5530485515520936,-0.41292781072703233,-0.41292781072703233,0.03965766766041974,-0.3578263417200354,-0.6676978506562085,0.412471861925284,0.625866314583955,2.0100448717400776,-0.49658581124515616,-0.11613860568977677,1.0105179663695107,-1.7534654236202036,4.7385298944612435,0.06523411656369492,-0.011824157758994824,-0.22232443406475605,0.09070253409564899,-0.44067800799054646,-0.49658581124515616,-0.49658581124515616,-0.3032458564235702,-0.011824157758994824,0.460522082895191,-0.19559772347892793,0.5082068465574456,0.36404879012622693,-0.33047177855621607,-0.9651364301489054,4.7385298944612435,0.16647131175699767,2.5415711073347276,0.3152452291356413,0.19151921531853922,3.120491344892983,-0.2761470099076228,-0.011824157758994824,-0.6100808230827668,-1.4446036602064072,1.1194802025914279,-0.16899212443771205,-1.0888207132458592,2.4526072090297046,0.5319144280730378,0.24130912809996094,-0.41292781072703233,-0.5814925595785796,-0.22232443406475605,0.06523411656369492,0.09070253409564899,-0.037732006077157064,0.412471861925284,0.7184525652536403,0.013971984461395193,0.5555333123030265,0.6491388771216718,0.764249500072063,-0.11613860568977677,0.14131998091565823,0.26605328440668863,-1.1201939880656602,-0.011824157758994824,3.0047879739765255,-0.2491737041569007,-0.9043423207096438,0.5082068465574456,-1.3451913690083444,-1.78875250039885,0.09070253409564899,2.5768641425022323,0.21646479318514736,-0.38531114273962846,0.16647131175699767,-1.1201939880656602,0.06523411656369492,-0.5247469164830378,-0.16899212443771205,-0.16899212443771205,0.19151921531853922,-0.7259155280154393,0.460522082895191,2.19770002015505
| 3,447
|
External side of plasma membrane
| 8
| 21
| 3.039228
| 0.002372
|
P42892,P51790,P01130,P11279,P08183,P02786,Q13740,P43121
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
5,70,73,41,113,52,154,126
|
196,601,2811,1458,73,52,1616,507,1166,113,41,1618,1109,671,359,5,126,2018,70,154,2727
|
1.054317838750862,0.36404879012622693,-0.5247469164830378,-0.011824157758994824,3.0214219227005468,3.6443989474477476,-0.06375283048767906,0.43654311105882554,0.09070253409564899,1.9910092185928823,4.005368888045156,-0.06375283048767906,0.11606410191198446,0.3152452291356413,0.625866314583955,5.626549900164905,1.7388215146356225,-0.19559772347892793,3.0545841549970008,1.4154814144632912,-0.46856343097646624
| 3,447
|
Locomotory behavior
| 8
| 30
| 3.033646
| 0.002416
|
O75844,P05067,P51790,P07686,P50897,P54802,P10253,O15118
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
189,66,70,46,21,25,59,57
|
2326,57,2329,2004,189,1615,970,1031,66,46,2083,59,672,3213,1468,816,638,21,2529,70,25,3409,1412,2190,206,1882,2421,656,3024,1900
|
-0.3032458564235702,3.520478778498601,-0.3032458564235702,-0.19559772347892793,1.0978302599790803,-0.06375283048767906,0.16647131175699767,0.14131998091565823,3.185852181395418,3.8867761966938223,-0.22232443406475605,3.426283702043037,0.3152452291356413,-0.8144047886641401,-0.011824157758994824,0.24130912809996094,0.33969505804727207,4.832688203866245,-0.38531114273962846,3.0545841549970008,4.7385298944612435,-1.7183704220896816,0.013971984461395193,-0.2491737041569007,1.032454143437075,-0.14250621643165773,-0.33047177855621607,0.33969505804727207,-0.6388152651515875,-0.14250621643165773
| 3,447
|
Coarse facial features
| 9
| 70
| 3.028958
| 0.002454
|
P15586,P16278,P04066,P06280,Q99519,P07686,P10619,P54802,O00754
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,35,11,12,75,46,47,25,30
|
1155,2511,1606,30,2253,758,387,11,12,46,2083,47,1,35,405,2523,1543,2393,220,1247,2466,2584,2171,637,1255,815,2528,3411,25,2100,2664,2665,1411,2346,493,315,2402,1872,1794,291,2487,930,2604,107,1290,3287,2128,743,2041,1809,744,3355,3349,2691,3320,75,1074,2135,1981,2432,2991,1015,469,2562,1019,3352,1377,1021,322,3148
|
0.09070253409564899,-0.38531114273962846,-0.06375283048767906,4.49169826573745,-0.2761470099076228,0.26605328440668863,0.5790643592485345,5.238210069294953,5.096383797522485,3.8867761966938223,-0.22232443406475605,3.8568635354262555,6.058298299026471,4.165756851456292,0.5555333123030265,-0.38531114273962846,-0.037732006077157064,-0.33047177855621607,0.944268201707387,0.06523411656369492,-0.3578263417200354,-0.41292781072703233,-0.2491737041569007,0.33969505804727207,0.06523411656369492,0.24130912809996094,-0.38531114273962846,-1.7534654236202036,4.7385298944612435,-0.22232443406475605,-0.44067800799054646,-0.44067800799054646,0.013971984461395193,-0.3032458564235702,0.460522082895191,0.6954312126789955,-0.33047177855621607,-0.14250621643165773,-0.11613860568977677,0.7413917409113739,-0.3578263417200354,0.19151921531853922,-0.41292781072703233,2.104478107048702,0.06523411656369492,-0.9346541779980903,-0.22232443406475605,0.290698308478738,-0.19559772347892793,-0.11613860568977677,0.290698308478738,-1.1517537324747553,-1.1201939880656602,-0.44067800799054646,-0.9957915972367293,3.0047879739765255,0.14131998091565823,-0.22232443406475605,-0.16899212443771205,-0.33047177855621607,-0.6100808230827668,0.16647131175699767,0.5082068465574456,-0.38531114273962846,0.16647131175699767,-1.1201939880656602,0.03965766766041974,0.16647131175699767,0.6954312126789955,-0.7259155280154393
| 3,447
|
External encapsulating structure
| 9
| 37
| 3.02422
| 0.002493
|
Q5KU26,P19022,Q08380,P07602,P07942,P53634,P10909,Q5SZK8,Q92896
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
38,110,16,15,146,20,58,92,63
|
1526,505,970,1616,2462,15,146,3116,3311,58,1709,1394,860,110,2010,2580,671,606,478,639,1784,3312,376,2660,20,2595,16,408,782,185,2112,38,92,63,3166,2750,1305
|
-0.037732006077157064,0.43654311105882554,0.16647131175699767,-0.06375283048767906,-0.3578263417200354,4.95230803704758,1.4977414359476033,-0.7259155280154393,-0.9957915972367293,3.4892019402118737,-0.08988792448924106,0.013971984461395193,0.21646479318514736,2.0100448717400776,-0.19559772347892793,-0.41292781072703233,0.3152452291356413,0.36404879012622693,0.48440969406177936,0.33969505804727207,-0.11613860568977677,-0.9957915972367293,0.6025084155120215,-0.44067800799054646,4.872739253374519,-0.41292781072703233,4.95230803704758,0.5555333123030265,0.26605328440668863,1.1194802025914279,-0.22232443406475605,4.136820106166587,2.4526072090297046,3.3469394788706537,-0.7552547701634187,-0.46856343097646624,0.06523411656369492
| 3,447
|
Axon development
| 17
| 82
| 3.016646
| 0.002556
|
P35613,Q9UQB8,P05067,O14786,O75955,P42892,Q96G23,Q15334,P19022,P16949,P29317,O94813,P00374,Q15375,Q92859,Q13740,Q7L576
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,97,66,99,196,5,168,206,110,202,178,84,117,119,23,154,223
|
3035,1094,99,804,968,857,196,84,117,66,507,310,1168,905,2083,2085,202,1463,110,2393,178,3381,512,913,1546,160,359,2656,5,816,2177,3088,1863,2964,2475,1730,1188,1633,2103,2346,2669,493,2670,1949,1123,825,1639,154,1127,206,119,1954,2679,3302,1351,877,3354,223,1963,941,2130,23,883,168,1433,2555,3106,1074,657,2221,588,2136,2432,2063,1146,225,2146,1019,2069,1086,97,3176
|
-0.6676978506562085,0.11606410191198446,2.308023112336245,0.24130912809996094,0.16647131175699767,0.21646479318514736,1.054317838750862,2.6294966021683392,1.8950668629102478,3.185852181395418,0.43654311105882554,0.6954312126789955,0.09070253409564899,0.19151921531853922,-0.22232443406475605,-0.22232443406475605,1.032454143437075,-0.011824157758994824,2.0100448717400776,-0.33047177855621607,1.162570531532433,-1.3451913690083444,0.43654311105882554,0.19151921531853922,-0.037732006077157064,1.3739783978655824,0.625866314583955,-0.44067800799054646,5.626549900164905,0.24130912809996094,-0.2491737041569007,-0.6967305875166148,-0.14250621643165773,-0.6100808230827668,-0.3578263417200354,-0.08988792448924106,0.09070253409564899,-0.06375283048767906,-0.22232443406475605,-0.3032458564235702,-0.44067800799054646,0.460522082895191,-0.44067800799054646,-0.16899212443771205,0.11606410191198446,0.24130912809996094,-0.06375283048767906,1.4154814144632912,0.11606410191198446,1.032454143437075,1.8757230653380457,-0.16899212443771205,-0.44067800799054646,-0.9651364301489054,0.03965766766041974,0.21646479318514736,-1.1517537324747553,0.944268201707387,-0.16899212443771205,0.19151921531853922,-0.22232443406475605,4.792456598943272,0.21646479318514736,1.2902064105323907,0.013971984461395193,-0.38531114273962846,-0.6967305875166148,0.14131998091565823,0.33969505804727207,-0.2491737041569007,0.3883074039088583,-0.22232443406475605,-0.33047177855621607,-0.19559772347892793,0.11606410191198446,0.944268201707387,-0.22232443406475605,0.16647131175699767,-0.19559772347892793,0.14131998091565823,2.3444338300023935,-0.7552547701634187
| 3,447
|
Thickened skin
| 23
| 110
| 3.007629
| 0.002633
|
Q9NWM8,Q9H488,Q14126,P04066,P06280,P28070,O95817,P53634,P53602,Q13642,P16278,P98194,Q15555,Q07954,O75844,Q15125,Q14574,Q99519,Q14739,P21359,Q15800,P04062,P09493
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
400,399,137,11,12,389,386,20,279,291,35,298,316,60,189,68,69,75,87,220,344,114,236
|
1155,1156,854,1158,1529,757,2641,3112,2998,3037,189,2456,2332,600,386,2646,1458,3180,114,11,1705,12,1033,1167,236,633,2652,670,1928,1710,35,811,405,1463,2523,2707,220,2011,1247,389,979,2866,1035,1256,2396,2868,2714,1116,1262,2912,1627,279,1941,20,678,1472,1628,298,2346,1475,493,1635,60,1047,1794,291,137,69,87,68,1483,2284,519,316,1132,2969,344,2196,2777,2417,2733,2120,879,1427,3165,1745,2040,2217,744,1660,1212,75,1974,2428,1818,1591,1440,1509,3026,399,3359,3067,2992,400,2561,1146,1021,3309,962,2701
|
0.09070253409564899,0.09070253409564899,0.21646479318514736,0.09070253409564899,-0.037732006077157064,0.26605328440668863,-0.44067800799054646,-0.7259155280154393,-0.6388152651515875,-0.6676978506562085,1.0978302599790803,-0.3578263417200354,-0.3032458564235702,0.36404879012622693,0.5790643592485345,-0.44067800799054646,-0.011824157758994824,-0.7847504591189078,1.952786157251336,5.238210069294953,-0.08988792448924106,5.096383797522485,0.14131998091565823,0.09070253409564899,0.8773428842135269,0.33969505804727207,-0.44067800799054646,0.3152452291356413,-0.16899212443771205,-0.08988792448924106,4.165756851456292,0.24130912809996094,0.5555333123030265,-0.011824157758994824,-0.38531114273962846,-0.46856343097646624,0.944268201707387,-0.19559772347892793,0.06523411656369492,0.5790643592485345,0.16647131175699767,-0.5530485515520936,0.14131998091565823,0.06523411656369492,-0.33047177855621607,-0.5530485515520936,-0.46856343097646624,0.11606410191198446,0.06523411656369492,-0.5814925595785796,-0.06375283048767906,0.764249500072063,-0.16899212443771205,4.872739253374519,0.3152452291356413,-0.011824157758994824,-0.06375283048767906,0.7184525652536403,-0.3032458564235702,-0.011824157758994824,0.460522082895191,-0.06375283048767906,3.362871077444676,0.14131998091565823,-0.11613860568977677,0.7413917409113739,1.6193233192302938,3.1040662322378125,2.5415711073347276,3.120491344892983,-0.011824157758994824,-0.2761470099076228,0.43654311105882554,0.6954312126789955,0.11606410191198446,-0.6100808230827668,0.6491388771216718,-0.2491737041569007,-0.49658581124515616,-0.33047177855621607,-0.46856343097646624,-0.22232443406475605,0.21646479318514736,0.013971984461395193,-0.7552547701634187,-0.08988792448924106,-0.19559772347892793,-0.2491737041569007,0.290698308478738,-0.06375283048767906,0.09070253409564899,3.0047879739765255,-0.16899212443771205,-0.33047177855621607,-0.11613860568977677,-0.037732006077157064,0.013971984461395193,-0.011824157758994824,-0.6388152651515875,0.5790643592485345,-1.1835028638774374,-0.6676978506562085,-0.6100808230827668,0.5790643592485345,-0.38531114273962846,0.11606410191198446,0.16647131175699767,-0.9651364301489054,0.19151921531853922,-0.44067800799054646
| 3,447
|
Neuromuscular process
| 9
| 25
| 3.007463
| 0.002634
|
P07196,O75844,P05067,P17900,O14773,Q15334,P07686,P04062,P10253
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
310,189,66,4,10,206,46,114,59
|
10,595,857,189,114,66,310,46,59,634,4,974,1468,816,916,2529,3049,729,206,1882,1492,346,1963,656,1074
|
5.276511437873593,0.36404879012622693,0.21646479318514736,1.0978302599790803,1.952786157251336,3.185852181395418,0.6954312126789955,3.8867761966938223,3.426283702043037,0.33969505804727207,5.796784418092093,0.16647131175699767,-0.011824157758994824,0.24130912809996094,0.19151921531853922,-0.38531114273962846,-0.6676978506562085,0.290698308478738,1.032454143437075,-0.14250621643165773,-0.011824157758994824,0.6491388771216718,-0.16899212443771205,0.33969505804727207,0.14131998091565823
| 3,447
|
Abnormal form of the vertebral bodies
| 15
| 92
| 3.006333
| 0.002644
|
P15586,P16278,Q15125,Q32P28,P10644,Q9Y619,P04066,Q99519,P48735,P51798,Q9UBM7,O75874,Q14739,P54802,O00754
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,35,68,185,193,103,11,75,111,209,86,55,87,25,30
|
1155,1688,30,1156,1691,758,2860,505,1162,2257,2389,2005,55,2952,387,1324,1458,11,1166,193,1,35,2518,3152,1543,2393,220,3004,1711,2864,2583,2584,1332,2467,3042,540,358,111,2765,1784,209,3411,25,1472,1187,2664,2770,2345,1475,493,2028,450,612,2403,3301,87,683,930,68,2286,1484,185,1956,3343,828,2605,1206,1573,301,412,347,283,1811,1071,793,1505,75,2220,3275,469,3414,86,891,2562,3352,1307,2855,1993,1994,962,3148,103
|
0.09070253409564899,-0.08988792448924106,4.49169826573745,0.09070253409564899,-0.08988792448924106,0.26605328440668863,-0.5530485515520936,0.43654311105882554,0.09070253409564899,-0.2761470099076228,-0.33047177855621607,-0.19559772347892793,3.5826739461700328,-0.6100808230827668,0.5790643592485345,0.03965766766041974,-0.011824157758994824,5.238210069294953,0.09070253409564899,1.0761096734158762,6.058298299026471,4.165756851456292,-0.38531114273962846,-0.7552547701634187,-0.037732006077157064,-0.33047177855621607,0.944268201707387,-0.6388152651515875,-0.08988792448924106,-0.5530485515520936,-0.41292781072703233,-0.41292781072703233,0.03965766766041974,-0.3578263417200354,-0.6676978506562085,0.412471861925284,0.625866314583955,2.0100448717400776,-0.49658581124515616,-0.11613860568977677,1.0105179663695107,-1.7534654236202036,4.7385298944612435,-0.011824157758994824,0.09070253409564899,-0.44067800799054646,-0.49658581124515616,-0.3032458564235702,-0.011824157758994824,0.460522082895191,-0.19559772347892793,0.5082068465574456,0.36404879012622693,-0.33047177855621607,-0.9651364301489054,2.5415711073347276,0.3152452291356413,0.19151921531853922,3.120491344892983,-0.2761470099076228,-0.011824157758994824,1.1194802025914279,-0.16899212443771205,-1.0888207132458592,0.24130912809996094,-0.41292781072703233,0.09070253409564899,-0.037732006077157064,0.7184525652536403,0.5555333123030265,0.6491388771216718,0.764249500072063,-0.11613860568977677,0.14131998091565823,0.26605328440668863,-0.011824157758994824,3.0047879739765255,-0.2491737041569007,-0.9043423207096438,0.5082068465574456,-1.78875250039885,2.5768641425022323,0.21646479318514736,-0.38531114273962846,-1.1201939880656602,0.06523411656369492,-0.5247469164830378,-0.16899212443771205,-0.16899212443771205,0.19151921531853922,-0.7259155280154393,2.19770002015505
| 3,447
|
Protease
| 17
| 120
| 2.999495
| 0.002704
|
O75844,Q5BJF2,Q9HB40,P42892,Q9UIQ6,Q86TI2,Q92820,O14773,Q13510,Q9H3G5,P10619,Q8NHP8,P42785,P53634,P02786,Q9BYT8,P55786
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
189,129,3,5,7,199,42,10,43,13,47,17,49,20,52,186,123
|
1762,2150,2151,10,403,246,1697,2757,189,568,1323,2862,52,668,765,47,2161,2652,1170,1618,1109,906,1246,3369,3119,1175,3085,1622,3120,2467,358,2656,49,5,1402,287,2019,2343,720,1041,2589,20,920,1406,774,123,608,1725,2100,1947,1733,1045,2028,1872,43,391,2408,1481,2676,205,2410,2678,2679,1349,1800,129,2290,2114,1644,522,2732,2117,3304,2883,736,199,366,1884,2421,619,17,3287,2039,2983,742,42,1292,3021,2782,1580,1969,1658,3135,1008,1584,1662,2892,3024,1975,2221,3444,1076,186,1144,13,2500,3,2236,1907,278,1681,1520,2800,7,628,535,1090,3176,3033,2379
|
-0.11613860568977677,-0.2491737041569007,-0.2491737041569007,5.276511437873593,0.5555333123030265,0.8548811891149231,-0.08988792448924106,-0.49658581124515616,1.0978302599790803,0.3883074039088583,0.03965766766041974,-0.5530485515520936,3.6443989474477476,0.3152452291356413,0.26605328440668863,3.8568635354262555,-0.2491737041569007,-0.44067800799054646,0.09070253409564899,-0.06375283048767906,0.11606410191198446,0.19151921531853922,0.06523411656369492,-1.2799168876410205,-0.7259155280154393,0.09070253409564899,-0.6967305875166148,-0.06375283048767906,-0.7259155280154393,-0.3578263417200354,0.625866314583955,-0.44067800799054646,3.7816081165133633,5.626549900164905,0.013971984461395193,0.7413917409113739,-0.19559772347892793,-0.3032458564235702,0.290698308478738,0.14131998091565823,-0.41292781072703233,4.872739253374519,0.19151921531853922,0.013971984461395193,0.26605328440668863,1.7782070510206058,0.36404879012622693,-0.08988792448924106,-0.22232443406475605,-0.16899212443771205,-0.08988792448924106,0.14131998091565823,-0.19559772347892793,-0.14250621643165773,3.9610928617452967,0.5790643592485345,-0.33047177855621607,-0.011824157758994824,-0.44067800799054646,1.032454143437075,-0.33047177855621607,-0.44067800799054646,-0.44067800799054646,0.03965766766041974,-0.11613860568977677,1.6793270618899536,-0.2761470099076228,-0.22232443406475605,-0.06375283048767906,0.43654311105882554,-0.46856343097646624,-0.22232443406475605,-0.9651364301489054,-0.5530485515520936,0.290698308478738,1.054317838750862,0.625866314583955,-0.14250621643165773,-0.33047177855621607,0.36404879012622693,4.939095447485741,-0.9346541779980903,-0.19559772347892793,-0.6100808230827668,0.290698308478738,4.005368888045156,0.06523411656369492,-0.6388152651515875,-0.49658581124515616,-0.037732006077157064,-0.16899212443771205,-0.06375283048767906,-0.7259155280154393,0.16647131175699767,-0.037732006077157064,-0.06375283048767906,-0.5530485515520936,-0.6388152651515875,-0.16899212443771205,-0.2491737041569007,-8.760220971245422,0.14131998091565823,1.1194802025914279,0.11606410191198446,5.096383797522485,-0.3578263417200354,5.856849705901865,-0.2491737041569007,-0.14250621643165773,0.7870265918459427,-0.06375283048767906,-0.011824157758994824,-0.49658581124515616,5.503041426277297,0.36404879012622693,0.43654311105882554,0.14131998091565823,-0.7552547701634187,-0.6388152651515875,-0.3032458564235702
| 3,447
|
Membrane lipid catabolic process
| 8
| 13
| 2.996941
| 0.002727
|
P17900,Q13510,P04066,P06280,P07686,P06865,Q99519,P50897
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,43,11,12,46,14,75,21
|
600,114,11,12,14,46,4,21,1189,43,75,369,2503
|
0.36404879012622693,1.952786157251336,5.238210069294953,5.096383797522485,4.991829849894577,3.8867761966938223,5.796784418092093,4.832688203866245,0.09070253409564899,3.9610928617452967,3.0047879739765255,0.625866314583955,-0.3578263417200354
| 3,447
|
Endopeptidase activity
| 18
| 68
| 2.994359
| 0.00275
|
O75844,P42892,P48147,Q9UPU5,O14773,Q13867,Q14790,P28070,O43847,P40818,Q9NZ08,P20618,Q92542,P53634,P28072,P60900,Q9BYT8,P49721
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
189,5,287,201,10,391,205,389,246,358,278,426,50,20,115,250,186,91
|
10,246,2757,189,568,971,668,1170,1618,1109,426,3119,1777,389,115,712,1622,2091,2467,358,2656,5,1402,287,1179,91,720,1041,20,1406,774,250,1947,2028,782,391,1481,2676,205,2600,1349,454,2290,1644,2730,2732,2117,737,619,2983,50,742,1292,883,1580,1008,1662,2892,1434,1975,2986,186,1144,278,1520,201,1090,3176
|
5.276511437873593,0.8548811891149231,-0.49658581124515616,1.0978302599790803,0.3883074039088583,0.16647131175699767,0.3152452291356413,0.09070253409564899,-0.06375283048767906,0.11606410191198446,0.5319144280730378,-0.7259155280154393,-0.11613860568977677,0.5790643592485345,1.952786157251336,0.290698308478738,-0.06375283048767906,-0.22232443406475605,-0.3578263417200354,0.625866314583955,-0.44067800799054646,5.626549900164905,0.013971984461395193,0.7413917409113739,0.09070253409564899,2.470484601896555,0.290698308478738,0.14131998091565823,4.872739253374519,0.013971984461395193,0.26605328440668863,0.8548811891149231,-0.16899212443771205,-0.19559772347892793,0.26605328440668863,0.5790643592485345,-0.011824157758994824,-0.44067800799054646,1.032454143437075,-0.41292781072703233,0.03965766766041974,0.5082068465574456,-0.2761470099076228,-0.06375283048767906,-0.46856343097646624,-0.46856343097646624,-0.22232443406475605,0.290698308478738,0.36404879012622693,-0.6100808230827668,3.736124836573613,0.290698308478738,0.06523411656369492,0.21646479318514736,-0.037732006077157064,0.16647131175699767,-0.06375283048767906,-0.5530485515520936,0.013971984461395193,-0.16899212443771205,-0.6100808230827668,1.1194802025914279,0.11606410191198446,0.7870265918459427,-0.011824157758994824,1.054317838750862,0.14131998091565823,-0.7552547701634187
| 3,447
|
Liposaccharide metabolic process
| 8
| 18
| 2.988438
| 0.002804
|
P16278,P17900,P04066,P06280,Q99519,P07686,P06865,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
35,4,11,12,75,46,14,114
|
1320,114,11,12,14,46,35,4,1189,377,875,3426,742,2365,2691,75,147,1021
|
0.03965766766041974,1.952786157251336,5.238210069294953,5.096383797522485,4.991829849894577,3.8867761966938223,4.165756851456292,5.796784418092093,0.09070253409564899,0.6025084155120215,0.21646479318514736,-2.0410879278253518,0.290698308478738,-0.3032458564235702,-0.44067800799054646,3.0047879739765255,1.4977414359476033,0.16647131175699767
| 3,447
|
Gliogenesis
| 10
| 57
| 2.985805
| 0.002828
|
P05067,Q96G23,P01130,P07686,P19022,P07942,Q92542,P04062,P10909,Q07954
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,168,73,46,110,146,50,114,58,60
|
803,757,2386,2388,1612,2330,73,114,1616,66,1032,46,146,488,1537,2083,58,405,110,220,1249,2466,3381,1035,1937,1255,1177,1468,816,3087,1261,1944,290,2103,2346,2670,60,1637,2348,3089,1279,1479,3129,2284,831,2040,50,2687,743,168,1503,2045,2063,351,1830,2323,798
|
0.24130912809996094,0.26605328440668863,-0.33047177855621607,-0.33047177855621607,-0.06375283048767906,-0.3032458564235702,3.0214219227005468,1.952786157251336,-0.06375283048767906,3.185852181395418,0.14131998091565823,3.8867761966938223,1.4977414359476033,0.460522082895191,-0.037732006077157064,-0.22232443406475605,3.4892019402118737,0.5555333123030265,2.0100448717400776,0.944268201707387,0.06523411656369492,-0.3578263417200354,-1.3451913690083444,0.14131998091565823,-0.16899212443771205,0.06523411656369492,0.09070253409564899,-0.011824157758994824,0.24130912809996094,-0.6967305875166148,0.06523411656369492,-0.16899212443771205,0.7413917409113739,-0.22232443406475605,-0.3032458564235702,-0.44067800799054646,3.362871077444676,-0.06375283048767906,-0.3032458564235702,-0.6967305875166148,0.06523411656369492,-0.011824157758994824,-0.7259155280154393,-0.2761470099076228,0.24130912809996094,-0.19559772347892793,3.736124836573613,-0.44067800799054646,0.290698308478738,1.2902064105323907,-0.011824157758994824,-0.19559772347892793,-0.19559772347892793,0.6491388771216718,-0.11613860568977677,-0.2761470099076228,0.26605328440668863
| 3,447
|
Azurophil granule membrane
| 10
| 21
| 2.979603
| 0.002886
|
O15260,Q9NV96,P11279,Q9NQX7,P07602,P42785,Q92542,Q6IAA8,P27105,P10253
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
98,271,41,44,15,49,50,238,53,59
|
98,2642,597,15,59,41,53,2469,49,865,481,2027,238,1965,50,2986,284,44,271,2750,2375
|
2.326250857937109,-0.44067800799054646,0.36404879012622693,4.95230803704758,3.426283702043037,4.005368888045156,3.6443989474477476,-0.3578263417200354,3.7816081165133633,0.21646479318514736,0.48440969406177936,-0.19559772347892793,0.8773428842135269,-0.16899212443771205,3.736124836573613,-0.6100808230827668,0.764249500072063,3.9610928617452967,0.80972375426467,-0.46856343097646624,-0.3032458564235702
| 3,447
|
Cellular carbohydrate metabolic process
| 11
| 61
| 2.971553
| 0.002963
|
O75844,O43505,P16278,Q9BYT8,Q15185,Q7LGA3,P48735,O75874,Q14108,P10253,Q9NX62
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
189,65,35,186,169,107,111,55,26,59,94
|
2857,3279,1607,65,2004,1770,189,55,2908,2333,602,1706,59,1105,1773,973,35,1541,1464,2579,1035,981,1255,2174,111,1862,1552,2529,1180,2766,3010,2820,2477,2531,1871,2667,2871,2345,2278,2028,782,1478,26,3130,1952,169,1737,2195,1798,107,213,1580,2784,2046,186,2628,698,2797,94,2752,3230
|
-0.5530485515520936,-0.9346541779980903,-0.06375283048767906,3.2021083972634283,-0.19559772347892793,-0.11613860568977677,1.0978302599790803,3.5826739461700328,-0.5814925595785796,-0.3032458564235702,0.36404879012622693,-0.08988792448924106,3.426283702043037,0.11606410191198446,-0.11613860568977677,0.16647131175699767,4.165756851456292,-0.037732006077157064,-0.011824157758994824,-0.41292781072703233,0.14131998091565823,0.16647131175699767,0.06523411656369492,-0.2491737041569007,2.0100448717400776,-0.14250621643165773,-0.037732006077157064,-0.38531114273962846,0.09070253409564899,-0.49658581124515616,-0.6388152651515875,-0.5247469164830378,-0.3578263417200354,-0.38531114273962846,-0.14250621643165773,-0.44067800799054646,-0.5530485515520936,-0.3032458564235702,-0.2761470099076228,-0.19559772347892793,0.26605328440668863,-0.011824157758994824,4.7385298944612435,-0.7259155280154393,-0.16899212443771205,1.247929148925315,-0.08988792448924106,-0.2491737041569007,-0.11613860568977677,2.104478107048702,0.9885086777190719,-0.037732006077157064,-0.49658581124515616,-0.19559772347892793,1.1194802025914279,-0.41292781072703233,0.3152452291356413,-0.49658581124515616,2.416723651268817,-0.46856343097646624,-0.8144047886641401
| 3,447
|
Steroid metabolic process
| 12
| 72
| 2.968323
| 0.002994
|
P05067,Q15125,Q15392,P01130,Q13510,P38571,Q9UBM7,Q14739,O15118,O76062,P61916,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,68,9,73,43,82,86,87,57,90,28,62
|
2002,57,806,2005,90,1844,600,3077,73,114,1459,66,3341,2086,670,1108,2518,1171,2581,3369,3153,1398,3381,2958,2712,2468,82,2397,2714,3325,2529,2659,1721,279,280,28,2966,2822,545,361,377,43,2774,1344,87,1196,68,1483,9,1197,2411,2969,344,431,2112,238,551,1359,62,3020,2784,1011,3225,557,1075,2792,887,86,1597,2321,2067,629
|
-0.19559772347892793,3.520478778498601,0.24130912809996094,-0.19559772347892793,2.506111945225677,-0.14250621643165773,0.36404879012622693,-0.6967305875166148,3.0214219227005468,1.952786157251336,-0.011824157758994824,3.185852181395418,-1.0888207132458592,-0.22232443406475605,0.3152452291356413,0.11606410191198446,-0.38531114273962846,0.09070253409564899,-0.41292781072703233,-1.2799168876410205,-0.7552547701634187,0.013971984461395193,-1.3451913690083444,-0.6100808230827668,-0.46856343097646624,-0.3578263417200354,2.733680073850197,-0.33047177855621607,-0.46856343097646624,-1.0266222601373636,-0.38531114273962846,-0.44067800799054646,-0.08988792448924106,0.764249500072063,0.764249500072063,4.602257829733616,-0.6100808230827668,-0.5247469164830378,0.412471861925284,0.625866314583955,0.6025084155120215,3.9610928617452967,-0.49658581124515616,0.03965766766041974,2.5415711073347276,0.09070253409564899,3.120491344892983,-0.011824157758994824,5.327333042658442,0.09070253409564899,-0.33047177855621607,-0.6100808230827668,0.6491388771216718,0.5319144280730378,-0.22232443406475605,0.8773428842135269,0.412471861925284,0.03965766766041974,3.3469394788706537,-0.6388152651515875,-0.49658581124515616,0.16647131175699767,-0.8144047886641401,0.412471861925284,0.14131998091565823,-0.49658581124515616,0.21646479318514736,2.5768641425022323,-0.037732006077157064,-0.2761470099076228,-0.19559772347892793,0.36404879012622693
| 3,447
|
Cell morphogenesis involved in neuron differentiation
| 17
| 100
| 2.967469
| 0.003003
|
P35613,Q9UQB8,P05067,O14786,O75955,Q13641,P42892,Q15334,P19022,P16949,P29317,O94813,Q15375,Q92859,P46934,Q13740,Q7L576
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,97,66,99,196,37,5,206,110,202,178,84,119,23,184,154,223
|
3035,1094,1314,338,99,804,1609,2257,857,196,84,1390,1615,66,507,310,1168,905,2083,202,1463,110,1620,178,512,913,160,359,5,816,2177,184,3088,1863,1265,2964,2475,1867,1730,1188,1633,2103,2346,2669,493,545,1412,2670,1562,3156,1949,825,1639,37,154,1279,1127,392,2675,206,119,1954,2679,3302,1351,877,581,3354,223,618,1963,941,2130,23,883,1970,1433,349,2555,3106,1074,2221,463,588,2136,2432,1821,2063,2943,1681,1146,225,2146,1019,2069,1086,97,3430,2947,3176
|
-0.6676978506562085,0.11606410191198446,0.03965766766041974,0.6491388771216718,2.308023112336245,0.24130912809996094,-0.06375283048767906,-0.2761470099076228,0.21646479318514736,1.054317838750862,2.6294966021683392,0.013971984461395193,-0.06375283048767906,3.185852181395418,0.43654311105882554,0.6954312126789955,0.09070253409564899,0.19151921531853922,-0.22232443406475605,1.032454143437075,-0.011824157758994824,2.0100448717400776,-0.06375283048767906,1.162570531532433,0.43654311105882554,0.19151921531853922,1.3739783978655824,0.625866314583955,5.626549900164905,0.24130912809996094,-0.2491737041569007,1.1194802025914279,-0.6967305875166148,-0.14250621643165773,0.06523411656369492,-0.6100808230827668,-0.3578263417200354,-0.14250621643165773,-0.08988792448924106,0.09070253409564899,-0.06375283048767906,-0.22232443406475605,-0.3032458564235702,-0.44067800799054646,0.460522082895191,0.412471861925284,0.013971984461395193,-0.44067800799054646,-0.037732006077157064,-0.7552547701634187,-0.16899212443771205,0.24130912809996094,-0.06375283048767906,4.136820106166587,1.4154814144632912,0.06523411656369492,0.11606410191198446,0.5790643592485345,-0.44067800799054646,1.032454143437075,1.8757230653380457,-0.16899212443771205,-0.44067800799054646,-0.9651364301489054,0.03965766766041974,0.21646479318514736,0.3883074039088583,-1.1517537324747553,0.944268201707387,0.36404879012622693,-0.16899212443771205,0.19151921531853922,-0.22232443406475605,4.792456598943272,0.21646479318514736,-0.16899212443771205,0.013971984461395193,0.6491388771216718,-0.38531114273962846,-0.6967305875166148,0.14131998091565823,-0.2491737041569007,0.5082068465574456,0.3883074039088583,-0.22232443406475605,-0.33047177855621607,-0.11613860568977677,-0.19559772347892793,-0.5814925595785796,-0.06375283048767906,0.11606410191198446,0.944268201707387,-0.22232443406475605,0.16647131175699767,-0.19559772347892793,0.14131998091565823,2.3444338300023935,-2.1520518234959054,-0.5814925595785796,-0.7552547701634187
| 3,447
|
Abnormality of the gingiva
| 8
| 54
| 2.947021
| 0.003209
|
P16278,Q15392,Q99519,P53634,Q9UBM7,Q14739,Q14108,O00754
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,9,75,20,86,87,26,30
|
2511,30,758,2641,2005,1102,2332,114,1033,193,1710,35,2463,1543,2584,1255,2177,639,20,1472,2664,2345,923,493,1791,3156,2919,26,87,2108,930,9,3396,3343,433,935,2200,3195,1000,883,1212,2691,75,1818,2057,2991,3067,2561,86,2562,3352,1307,962,3148
|
-0.38531114273962846,4.49169826573745,0.26605328440668863,-0.44067800799054646,-0.19559772347892793,0.11606410191198446,-0.3032458564235702,1.952786157251336,0.14131998091565823,1.0761096734158762,-0.08988792448924106,4.165756851456292,-0.3578263417200354,-0.037732006077157064,-0.41292781072703233,0.06523411656369492,-0.2491737041569007,0.33969505804727207,4.872739253374519,-0.011824157758994824,-0.44067800799054646,-0.3032458564235702,0.19151921531853922,0.460522082895191,-0.11613860568977677,-0.7552547701634187,-0.5814925595785796,4.7385298944612435,2.5415711073347276,-0.22232443406475605,0.19151921531853922,5.327333042658442,-1.4446036602064072,-1.0888207132458592,0.5319144280730378,0.19151921531853922,-0.2491737041569007,-0.7847504591189078,0.16647131175699767,0.21646479318514736,0.09070253409564899,-0.44067800799054646,3.0047879739765255,-0.11613860568977677,-0.19559772347892793,-0.6100808230827668,-0.6676978506562085,-0.38531114273962846,2.5768641425022323,-0.38531114273962846,-1.1201939880656602,0.06523411656369492,0.19151921531853922,-0.7259155280154393
| 3,447
|
Carbohydrate binding
| 9
| 47
| 2.946993
| 0.003209
|
P35613,Q9UBG0,Q5KU26,O75503,Q10472,Q32P28,P10253,O00754,P11717
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
160,64,38,8,212,185,59,30,31
|
1688,30,505,1320,8,857,2516,602,1772,1706,59,2086,31,2087,973,489,860,2579,671,2013,981,160,2170,2818,639,1552,2766,2667,1273,1475,2278,232,212,329,2405,2538,2599,430,1798,185,38,381,1363,3306,2558,1757,64
|
-0.08988792448924106,4.49169826573745,0.43654311105882554,0.03965766766041974,5.390468925074161,0.21646479318514736,-0.38531114273962846,0.36404879012622693,-0.11613860568977677,-0.08988792448924106,3.426283702043037,-0.22232443406475605,4.393795198319631,-0.22232443406475605,0.16647131175699767,0.460522082895191,0.21646479318514736,-0.41292781072703233,0.3152452291356413,-0.19559772347892793,0.16647131175699767,1.3739783978655824,-0.2491737041569007,-0.5247469164830378,0.33969505804727207,-0.037732006077157064,-0.49658581124515616,-0.44067800799054646,0.06523411656369492,-0.011824157758994824,-0.2761470099076228,0.899727495712953,0.9885086777190719,0.6723269112207332,-0.33047177855621607,-0.38531114273962846,-0.41292781072703233,0.5319144280730378,-0.11613860568977677,1.1194802025914279,4.136820106166587,0.6025084155120215,0.03965766766041974,-0.9651364301489054,-0.38531114273962846,-0.08988792448924106,3.282894405814692
| 3,447
|
Late endosome
| 22
| 68
| 2.935808
| 0.003327
|
Q8IV08,Q7Z3C6,Q9NV96,P20645,P07602,Q14108,Q9UQN3,P11717,P11279,Q9Y2Q5,Q15012,O15118,Q9UNK0,P10644,Q8IY95,P51790,P01130,O15400,Q9BRK5,Q96A57,Q9UEU0,Q6IAA8
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,132,271,142,15,26,285,31,41,322,56,57,321,193,331,70,73,210,89,234,105,238
|
1999,2382,57,210,1318,1768,569,73,2462,15,3116,193,2391,41,31,707,142,1249,2466,1258,641,70,481,819,1789,2346,1791,26,56,1054,238,132,0,331,1494,3100,3060,234,744,1069,349,656,1011,1814,3358,89,3138,3444,2558,1979,2694,1439,1509,839,2308,435,271,797,2750,2630,3109,105,754,321,285,322,502,2947
|
-0.19559772347892793,-0.33047177855621607,3.520478778498601,0.9885086777190719,0.03965766766041974,-0.11613860568977677,0.3883074039088583,3.0214219227005468,-0.3578263417200354,4.95230803704758,-0.7259155280154393,1.0761096734158762,-0.33047177855621607,4.005368888045156,4.393795198319631,0.290698308478738,1.5587987614920094,0.06523411656369492,-0.3578263417200354,0.06523411656369492,0.33969505804727207,3.0545841549970008,0.48440969406177936,0.24130912809996094,-0.11613860568977677,-0.3032458564235702,-0.11613860568977677,4.7385298944612435,3.55163571681315,0.14131998091565823,0.8773428842135269,1.6593829626856886,6.174862566674202,0.6723269112207332,-0.011824157758994824,-0.6967305875166148,-0.6676978506562085,0.899727495712953,0.290698308478738,0.14131998091565823,0.6491388771216718,0.33969505804727207,0.16647131175699767,-0.11613860568977677,-1.1835028638774374,2.5415711073347276,-0.7259155280154393,-8.760220971245422,-0.38531114273962846,-0.16899212443771205,-0.44067800799054646,0.013971984461395193,-0.011824157758994824,0.24130912809996094,-0.2761470099076228,0.5319144280730378,0.80972375426467,0.26605328440668863,-0.46856343097646624,-0.41292781072703233,-0.6967305875166148,2.179150607376429,0.290698308478738,0.6954312126789955,0.764249500072063,0.6954312126789955,0.460522082895191,-0.5814925595785796
| 3,447
|
Coated vesicle membrane
| 11
| 61
| 2.933383
| 0.003353
|
P04439,P01130,Q9UEU0,P20645,O43731,Q8NDZ4,O43493,P10321,P02786,Q14108,P11717
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
72,73,105,142,80,145,18,83,52,26,31
|
2511,2638,2806,1098,18,80,1695,1535,3074,2572,1455,1030,762,1390,1922,569,73,52,72,357,83,2391,31,539,142,2268,861,638,639,479,481,1941,1117,721,1554,516,1628,778,1121,1275,26,1796,292,3420,1484,519,882,145,1295,1824,661,1084,3436,105,2146,1599,753,2633,188,3368,966
|
-0.38531114273962846,-0.44067800799054646,-0.5247469164830378,0.11606410191198446,4.925863408400397,2.750906555502383,-0.08988792448924106,-0.037732006077157064,-0.6967305875166148,-0.41292781072703233,-0.011824157758994824,0.14131998091565823,0.26605328440668863,0.013971984461395193,-0.16899212443771205,0.3883074039088583,3.0214219227005468,3.6443989474477476,3.0380205848750497,0.625866314583955,2.699110242674545,-0.33047177855621607,4.393795198319631,0.412471861925284,1.5587987614920094,-0.2761470099076228,0.21646479318514736,0.33969505804727207,0.33969505804727207,0.48440969406177936,0.48440969406177936,-0.16899212443771205,0.11606410191198446,0.290698308478738,-0.037732006077157064,0.43654311105882554,-0.06375283048767906,0.26605328440668863,0.11606410191198446,0.06523411656369492,4.7385298944612435,-0.11613860568977677,0.7413917409113739,-1.8599003564047882,-0.011824157758994824,0.43654311105882554,0.21646479318514736,1.5181538302974797,0.06523411656369492,-0.11613860568977677,0.33969505804727207,0.14131998091565823,-2.933785129533608,2.179150607376429,-0.22232443406475605,-0.037732006077157064,0.290698308478738,-0.41292781072703233,1.1194802025914279,-1.2475813324366078,0.19151921531853922
| 3,447
|
Biological process involved in symbiotic interaction
| 15
| 83
| 2.932048
| 0.003367
|
P35613,Q9Y624,P08195,O14786,P01130,P11279,P78310,P29317,P02786,P27105,Q9BTY2,O15118,Q14108,Q8WTV0,P11717
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,121,161,99,73,41,136,178,52,53,24,57,26,62,31
|
2450,1450,1023,99,57,1608,1768,1102,569,73,52,1703,507,1032,1166,161,905,1239,1926,2910,2391,41,3416,31,1618,444,1542,3296,3342,3004,1620,53,178,2525,160,2173,2180,1403,641,2528,136,3433,315,1343,2402,925,1414,3089,926,1795,2484,26,1875,3016,343,1737,940,3402,1966,62,3060,2620,1069,2132,1071,3136,1895,3358,24,181,415,435,797,2630,2375,3109,1759,754,1227,285,502,3363,121
|
-0.3578263417200354,-0.011824157758994824,0.14131998091565823,2.308023112336245,3.520478778498601,-0.06375283048767906,-0.11613860568977677,0.11606410191198446,0.3883074039088583,3.0214219227005468,3.6443989474477476,-0.08988792448924106,0.43654311105882554,0.14131998091565823,0.09070253409564899,1.3531319100008414,0.19151921531853922,0.06523411656369492,-0.16899212443771205,-0.5814925595785796,-0.33047177855621607,4.005368888045156,-1.8242310197178253,4.393795198319631,-0.06375283048767906,0.5082068465574456,-0.037732006077157064,-0.9651364301489054,-1.0888207132458592,-0.6388152651515875,-0.06375283048767906,3.6443989474477476,1.162570531532433,-0.38531114273962846,1.3739783978655824,-0.2491737041569007,-0.2491737041569007,0.013971984461395193,0.33969505804727207,-0.38531114273962846,1.6193233192302938,-2.340694476266564,0.6954312126789955,0.03965766766041974,-0.33047177855621607,0.19151921531853922,0.013971984461395193,-0.6967305875166148,0.19151921531853922,-0.11613860568977677,-0.3578263417200354,4.7385298944612435,-0.14250621643165773,-0.6388152651515875,0.6491388771216718,-0.08988792448924106,0.19151921531853922,-1.511870415093519,-0.16899212443771205,3.3469394788706537,-0.6676978506562085,-0.41292781072703233,0.14131998091565823,-0.22232443406475605,0.14131998091565823,-0.7259155280154393,-0.14250621643165773,-1.1835028638774374,4.752042300962526,1.1410600971660143,0.5555333123030265,0.5319144280730378,0.26605328440668863,-0.41292781072703233,-0.3032458564235702,-0.6967305875166148,-0.08988792448924106,0.290698308478738,0.09070253409564899,0.764249500072063,0.460522082895191,-1.2154443741784,1.8368772029414835
| 3,447
|
Hepatosplenomegaly
| 8
| 43
| 2.922441
| 0.003473
|
P16278,Q13510,Q99519,P07686,P10619,P38571,Q14739,O00754
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,43,75,46,47,82,87,30
|
2511,30,1320,1029,2005,114,2333,46,47,263,35,3342,2166,671,2170,637,82,1255,1780,2959,3283,1782,1552,209,3047,2278,1189,782,43,3370,87,2486,2543,2974,2130,744,1811,1071,75,2376,1991,1228,503
|
-0.38531114273962846,4.49169826573745,0.03965766766041974,0.14131998091565823,-0.19559772347892793,1.952786157251336,-0.3032458564235702,3.8867761966938223,3.8568635354262555,0.80972375426467,4.165756851456292,-1.0888207132458592,-0.2491737041569007,0.3152452291356413,-0.2491737041569007,0.33969505804727207,2.733680073850197,0.06523411656369492,-0.11613860568977677,-0.6100808230827668,-0.9346541779980903,-0.11613860568977677,-0.037732006077157064,1.0105179663695107,-0.6676978506562085,-0.2761470099076228,0.09070253409564899,0.26605328440668863,3.9610928617452967,-1.2799168876410205,2.5415711073347276,-0.3578263417200354,-0.38531114273962846,-0.6100808230827668,-0.22232443406475605,0.290698308478738,-0.11613860568977677,0.14131998091565823,3.0047879739765255,-0.3032458564235702,-0.16899212443771205,0.09070253409564899,0.460522082895191
| 3,447
|
Alcohol metabolic process
| 15
| 86
| 2.919843
| 0.003502
|
P05067,Q15125,Q15392,P01130,Q13510,P48735,P04062,Q9NX62,Q9UBM7,O75874,Q14739,O15118,O76062,P61916,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,68,9,73,43,111,114,94,86,55,87,57,90,28,62
|
2857,57,854,1158,2327,899,1320,806,2005,55,90,1844,2908,117,3077,73,114,66,3078,2265,2086,972,670,1927,1108,2518,1541,3369,3441,1254,2958,2712,2397,2174,2714,111,3325,2962,1552,2529,2912,1721,279,280,3010,609,28,2966,2667,2822,2345,361,2028,377,43,1478,2774,1344,87,1196,68,1483,9,2969,344,2195,431,2731,1201,2126,2840,2422,62,304,3024,2786,557,838,3421,3026,559,2628,94,86,1597,2444
|
-0.5530485515520936,3.520478778498601,0.21646479318514736,0.09070253409564899,-0.3032458564235702,0.19151921531853922,0.03965766766041974,0.24130912809996094,-0.19559772347892793,3.5826739461700328,2.506111945225677,-0.14250621643165773,-0.5814925595785796,1.8950668629102478,-0.6967305875166148,3.0214219227005468,1.952786157251336,3.185852181395418,-0.6967305875166148,-0.2761470099076228,-0.22232443406475605,0.16647131175699767,0.3152452291356413,-0.16899212443771205,0.11606410191198446,-0.38531114273962846,-0.037732006077157064,-1.2799168876410205,-5.435792321266738,0.06523411656369492,-0.6100808230827668,-0.46856343097646624,-0.33047177855621607,-0.2491737041569007,-0.46856343097646624,2.0100448717400776,-1.0266222601373636,-0.6100808230827668,-0.037732006077157064,-0.38531114273962846,-0.5814925595785796,-0.08988792448924106,0.764249500072063,0.764249500072063,-0.6388152651515875,0.36404879012622693,4.602257829733616,-0.6100808230827668,-0.44067800799054646,-0.5247469164830378,-0.3032458564235702,0.625866314583955,-0.19559772347892793,0.6025084155120215,3.9610928617452967,-0.011824157758994824,-0.49658581124515616,0.03965766766041974,2.5415711073347276,0.09070253409564899,3.120491344892983,-0.011824157758994824,5.327333042658442,-0.6100808230827668,0.6491388771216718,-0.2491737041569007,0.5319144280730378,-0.46856343097646624,0.09070253409564899,-0.22232443406475605,-0.5247469164830378,-0.33047177855621607,3.3469394788706537,0.7184525652536403,-0.6388152651515875,-0.49658581124515616,0.412471861925284,0.24130912809996094,-1.8599003564047882,-0.6388152651515875,0.412471861925284,-0.41292781072703233,2.416723651268817,2.5768641425022323,-0.037732006077157064,-0.33047177855621607
| 3,447
|
Distal axon
| 14
| 59
| 2.909717
| 0.003618
|
P07196,P05067,P51114,Q13641,P51790,P0DP25,P78310,O75150,P80723,Q99720,Q06787,Q92859,P51116,Q7L576
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
310,66,288,37,70,104,136,262,266,51,315,23,313,223
|
3035,897,2385,1766,262,968,1841,66,310,1168,905,706,104,2391,539,2393,3342,978,1175,816,2177,1548,1863,288,313,70,1117,1338,136,266,2103,544,1790,315,870,363,37,2408,1127,3302,1878,877,223,1492,1494,618,2929,2130,23,883,944,1433,51,1681,1084,1020,3352,628,1227
|
-0.6676978506562085,0.19151921531853922,-0.33047177855621607,-0.11613860568977677,0.80972375426467,0.16647131175699767,-0.14250621643165773,3.185852181395418,0.6954312126789955,0.09070253409564899,0.19151921531853922,0.290698308478738,2.179150607376429,-0.33047177855621607,0.412471861925284,-0.33047177855621607,-1.0888207132458592,0.16647131175699767,0.09070253409564899,0.24130912809996094,-0.2491737041569007,-0.037732006077157064,-0.14250621643165773,0.7413917409113739,0.6954312126789955,3.0545841549970008,0.11606410191198446,0.03965766766041974,1.6193233192302938,0.80972375426467,-0.22232443406475605,0.412471861925284,-0.11613860568977677,0.6954312126789955,0.21646479318514736,0.625866314583955,4.136820106166587,-0.33047177855621607,0.11606410191198446,-0.9651364301489054,-0.14250621643165773,0.21646479318514736,0.944268201707387,-0.011824157758994824,-0.011824157758994824,0.36404879012622693,-0.5814925595785796,-0.22232443406475605,4.792456598943272,0.21646479318514736,0.19151921531853922,0.013971984461395193,3.6750880080144026,-0.06375283048767906,0.14131998091565823,0.16647131175699767,-1.1201939880656602,0.36404879012622693,0.09070253409564899
| 3,447
|
Calcium ion binding
| 20
| 87
| 2.907827
| 0.003639
|
Q14126,O75071,O60476,Q9UM22,Q07954,Q14574,P01130,O43852,P31949,P55327,O94813,P41208,Q9BRK5,Q02818,P67936,P80303,P0DP25,P19022,Q14257,Q9H223
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
137,22,149,27,60,69,73,77,203,211,84,216,89,95,226,101,104,110,116,252
|
1093,504,1764,1027,77,149,22,3074,857,1770,84,2952,761,73,1616,474,971,2462,668,3116,3311,104,1106,707,3248,1107,1394,811,1109,110,1244,2010,3342,671,2013,1934,1714,203,216,2173,2174,1548,3312,211,2661,1266,226,101,95,493,60,1562,3157,2191,137,116,3192,69,2675,409,522,936,828,3270,2295,2610,1965,412,1809,347,2845,2986,3167,89,1816,2936,252,270,400,564,3436,1447,2376,27,1086,2947,2250
|
0.11606410191198446,0.43654311105882554,-0.11613860568977677,0.14131998091565823,2.9042321491780596,1.477268471012952,4.805887326746089,-0.6967305875166148,0.21646479318514736,-0.11613860568977677,2.6294966021683392,-0.6100808230827668,0.26605328440668863,3.0214219227005468,-0.06375283048767906,0.48440969406177936,0.16647131175699767,-0.3578263417200354,0.3152452291356413,-0.7259155280154393,-0.9957915972367293,2.179150607376429,0.11606410191198446,0.290698308478738,-0.8741983970490654,0.11606410191198446,0.013971984461395193,0.24130912809996094,0.11606410191198446,2.0100448717400776,0.06523411656369492,-0.19559772347892793,-1.0888207132458592,0.3152452291356413,-0.19559772347892793,-0.16899212443771205,-0.08988792448924106,1.032454143437075,0.9664256387623936,-0.2491737041569007,-0.2491737041569007,-0.037732006077157064,-0.9957915972367293,0.9885086777190719,-0.44067800799054646,0.06523411656369492,0.9220357095144189,2.2530683333705355,2.3625723141377883,0.460522082895191,3.362871077444676,-0.037732006077157064,-0.7552547701634187,-0.2491737041569007,1.6193233192302938,1.9335980444265064,-0.7847504591189078,3.1040662322378125,-0.44067800799054646,0.5555333123030265,0.43654311105882554,0.19151921531853922,0.24130912809996094,-0.9043423207096438,-0.2761470099076228,-0.41292781072703233,-0.16899212443771205,0.5555333123030265,-0.11613860568977677,0.6491388771216718,-0.5247469164830378,-0.6100808230827668,-0.7552547701634187,2.5415711073347276,-0.11613860568977677,-0.5814925595785796,0.8548811891149231,0.80972375426467,0.5790643592485345,0.412471861925284,-2.933785129533608,0.013971984461395193,-0.3032458564235702,4.643360969007566,0.14131998091565823,-0.5814925595785796,-0.2491737041569007
| 3,447
|
Intra golgi and retrograde golgi to er traffic
| 35
| 98
| 2.905316
| 0.003669
|
Q14204,P20645,P18085,O43493,P61923,O60476,Q96FJ2,P11717,Q7Z6M1,Q16706,Q9UID3,Q5VZE5,Q9BVK6,Q9Y678,Q9BVA1,Q9BW19,Q9H0H5,O00461,Q92845,Q15042,P52907,P61163,O43731,Q10472,Q92538,P49755,O15260,Q13561,P04350,O00139,Q10471,Q9UJW0,Q9H2M9,O95249,O15498
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
649,142,509,18,516,149,555,31,33,430,307,299,464,188,588,465,467,71,333,453,572,574,80,212,483,479,98,363,474,592,232,499,497,356,372
|
592,71,2806,98,372,1318,2256,18,80,149,2904,1099,2572,1454,1457,858,356,474,31,509,142,2268,913,861,1113,816,1781,2869,715,638,479,1627,572,1941,1117,1471,574,516,1339,3012,1473,2478,3123,2666,922,923,870,232,212,3156,2823,1275,726,363,927,729,649,2486,683,453,1564,3420,430,1569,299,2605,33,1805,1650,943,792,483,333,555,1140,1364,1506,2427,1367,588,464,465,1438,467,2499,497,1016,1303,841,2898,1147,1084,307,499,2633,1311,188,1382
|
0.36404879012622693,3.0380205848750497,-0.5247469164830378,2.326250857937109,0.6025084155120215,0.03965766766041974,-0.2761470099076228,4.925863408400397,2.750906555502383,1.477268471012952,-0.5814925595785796,0.11606410191198446,-0.41292781072703233,-0.011824157758994824,-0.011824157758994824,0.21646479318514736,0.625866314583955,0.48440969406177936,4.393795198319631,0.43654311105882554,1.5587987614920094,-0.2761470099076228,0.19151921531853922,0.21646479318514736,0.11606410191198446,0.24130912809996094,-0.11613860568977677,-0.5530485515520936,0.290698308478738,0.33969505804727207,0.48440969406177936,-0.06375283048767906,0.3883074039088583,-0.16899212443771205,0.11606410191198446,-0.011824157758994824,0.3883074039088583,0.43654311105882554,0.03965766766041974,-0.6388152651515875,-0.011824157758994824,-0.3578263417200354,-0.7259155280154393,-0.44067800799054646,0.19151921531853922,0.19151921531853922,0.21646479318514736,0.899727495712953,0.9885086777190719,-0.7552547701634187,-0.5247469164830378,0.06523411656369492,0.290698308478738,0.625866314583955,0.19151921531853922,0.290698308478738,0.33969505804727207,-0.3578263417200354,0.3152452291356413,0.5082068465574456,-0.037732006077157064,-1.8599003564047882,0.5319144280730378,-0.037732006077157064,0.7184525652536403,-0.41292781072703233,4.266269685759162,-0.11613860568977677,-0.06375283048767906,0.19151921531853922,0.26605328440668863,0.48440969406177936,0.6723269112207332,0.412471861925284,0.11606410191198446,0.03965766766041974,-0.011824157758994824,-0.33047177855621607,0.03965766766041974,0.3883074039088583,0.5082068465574456,0.5082068465574456,0.013971984461395193,0.5082068465574456,-0.3578263417200354,0.460522082895191,0.16647131175699767,0.06523411656369492,0.24130912809996094,-0.5530485515520936,0.11606410191198446,0.14131998091565823,0.7184525652536403,0.460522082895191,-0.41292781072703233,0.06523411656369492,1.1194802025914279,0.03965766766041974
| 3,447
|
Glycosaminoglycan metabolism
| 7
| 13
| 2.905238
| 0.00367
|
O43505,P15586,P16278,Q7LGA3,P07686,P06865,P54802
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
65,1,35,107,46,14,25
|
1839,65,1234,14,46,1,35,25,107,584,793,214,1447
|
-0.14250621643165773,3.2021083972634283,0.06523411656369492,4.991829849894577,3.8867761966938223,6.058298299026471,4.165756851456292,4.7385298944612435,2.104478107048702,0.3883074039088583,0.26605328440668863,0.9885086777190719,0.013971984461395193
| 3,447
|
Hallucinations
| 6
| 47
| 2.901036
| 0.003719
|
P05067,O75503,P19022,P07602,P50897,O00754
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,8,110,15,21,30
|
2149,323,30,1764,1452,597,8,632,2575,114,66,15,1850,3117,3152,110,2089,2816,1112,1467,1258,1259,1116,21,3045,642,2184,2275,2715,1044,3314,1414,1878,652,1882,1420,1963,1574,743,656,3024,2739,557,2137,2750,2376,1990
|
-0.2491737041569007,0.6723269112207332,4.49169826573745,-0.11613860568977677,-0.011824157758994824,0.36404879012622693,5.390468925074161,0.33969505804727207,-0.41292781072703233,1.952786157251336,3.185852181395418,4.95230803704758,-0.14250621643165773,-0.7259155280154393,-0.7552547701634187,2.0100448717400776,-0.22232443406475605,-0.5247469164830378,0.11606410191198446,-0.011824157758994824,0.06523411656369492,0.06523411656369492,0.11606410191198446,4.832688203866245,-0.6676978506562085,0.33969505804727207,-0.2491737041569007,-0.2761470099076228,-0.46856343097646624,0.14131998091565823,-0.9957915972367293,0.013971984461395193,-0.14250621643165773,0.33969505804727207,-0.14250621643165773,0.013971984461395193,-0.16899212443771205,-0.037732006077157064,0.290698308478738,0.33969505804727207,-0.6388152651515875,-0.46856343097646624,0.412471861925284,-0.22232443406475605,-0.46856343097646624,-0.3032458564235702,-0.16899212443771205
| 3,447
|
Cherry red spot of the macula
| 7
| 10
| 2.898383
| 0.003751
|
P16278,P17900,Q13510,P07686,P10619,P07602,P06865
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,4,43,46,47,15,14
|
14,15,46,47,1540,35,4,43,75,2750
|
4.991829849894577,4.95230803704758,3.8867761966938223,3.8568635354262555,-0.037732006077157064,4.165756851456292,5.796784418092093,3.9610928617452967,3.0047879739765255,-0.46856343097646624
| 3,447
|
Metabolism of carbohydrates
| 8
| 98
| 2.891167
| 0.003838
|
P15586,O43505,P16278,P06865,P07686,P54802,P10253,O00754
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
1,65,35,14,46,25,59,30
|
2857,30,1839,65,1234,2079,1770,1389,2812,2459,2516,1703,2647,602,1772,14,46,1706,706,2335,59,263,1105,2086,3416,1851,973,1927,1709,1108,1,35,1541,2519,2520,489,1464,2579,1934,636,477,981,2585,2269,3040,2170,1401,3249,862,2818,2180,1862,1552,1180,2766,2589,3007,25,1264,3010,2594,2667,1273,2967,2278,723,2827,1345,2195,1798,1487,380,107,1285,2834,833,368,2038,1806,584,1967,1498,1579,2618,622,793,2050,1143,2742,3025,3107,2992,214,2143,1447,2376,2753,420
|
-0.5530485515520936,4.49169826573745,-0.14250621643165773,3.2021083972634283,0.06523411656369492,-0.22232443406475605,-0.11613860568977677,0.013971984461395193,-0.5247469164830378,-0.3578263417200354,-0.38531114273962846,-0.08988792448924106,-0.44067800799054646,0.36404879012622693,-0.11613860568977677,4.991829849894577,3.8867761966938223,-0.08988792448924106,0.290698308478738,-0.3032458564235702,3.426283702043037,0.80972375426467,0.11606410191198446,-0.22232443406475605,-1.8242310197178253,-0.14250621643165773,0.16647131175699767,-0.16899212443771205,-0.08988792448924106,0.11606410191198446,6.058298299026471,4.165756851456292,-0.037732006077157064,-0.38531114273962846,-0.38531114273962846,0.460522082895191,-0.011824157758994824,-0.41292781072703233,-0.16899212443771205,0.33969505804727207,0.48440969406177936,0.16647131175699767,-0.41292781072703233,-0.2761470099076228,-0.6676978506562085,-0.2491737041569007,0.013971984461395193,-0.8741983970490654,0.21646479318514736,-0.5247469164830378,-0.2491737041569007,-0.14250621643165773,-0.037732006077157064,0.09070253409564899,-0.49658581124515616,-0.41292781072703233,-0.6388152651515875,4.7385298944612435,0.06523411656369492,-0.6388152651515875,-0.41292781072703233,-0.44067800799054646,0.06523411656369492,-0.6100808230827668,-0.2761470099076228,0.290698308478738,-0.5247469164830378,0.03965766766041974,-0.2491737041569007,-0.11613860568977677,-0.011824157758994824,0.6025084155120215,2.104478107048702,0.06523411656369492,-0.5247469164830378,0.24130912809996094,0.625866314583955,-0.19559772347892793,-0.11613860568977677,0.3883074039088583,-0.16899212443771205,-0.011824157758994824,-0.037732006077157064,-0.41292781072703233,0.36404879012622693,0.26605328440668863,-0.19559772347892793,0.11606410191198446,-0.46856343097646624,-0.6388152651515875,-0.6967305875166148,-0.6100808230827668,0.9885086777190719,-0.22232443406475605,0.013971984461395193,-0.3032458564235702,-0.46856343097646624,0.5555333123030265
| 3,447
|
Lymphocyte mediated immunity
| 8
| 39
| 2.890736
| 0.003843
|
P04439,P11279,Q9BY67,Q9UQ84,P53634,P02786,P10909,Q07021
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
72,41,175,112,20,52,58,191
|
210,1695,595,1324,1615,52,72,1167,1104,2910,58,41,3151,3213,913,1624,1259,1334,481,642,20,1473,1189,191,2719,781,2973,2922,2199,829,2620,1430,1661,175,2794,486,797,1520,112
|
0.9885086777190719,-0.08988792448924106,0.36404879012622693,0.03965766766041974,-0.06375283048767906,3.6443989474477476,3.0380205848750497,0.09070253409564899,0.11606410191198446,-0.5814925595785796,3.4892019402118737,4.005368888045156,-0.7552547701634187,-0.8144047886641401,0.19151921531853922,-0.06375283048767906,0.06523411656369492,0.03965766766041974,0.48440969406177936,0.33969505804727207,4.872739253374519,-0.011824157758994824,0.09070253409564899,1.0978302599790803,-0.46856343097646624,0.26605328440668863,-0.6100808230827668,-0.5814925595785796,-0.2491737041569007,0.24130912809996094,-0.41292781072703233,0.013971984461395193,-0.06375283048767906,1.1840120855874656,-0.49658581124515616,0.48440969406177936,0.26605328440668863,-0.011824157758994824,2.0100448717400776
| 3,447
|
Dementia
| 16
| 61
| 2.890722
| 0.003844
|
P05067,P17900,Q8IY17,P54886,Q13510,P06865,P07602,O00429,P27544,P04062,Q06787,O15118,Q14108,P61916,Q9UQN3,Q7LG56
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
66,4,367,289,43,14,15,323,208,114,315,57,26,28,285,255
|
323,57,1764,1452,597,632,2575,1325,2006,3380,114,970,474,66,14,15,2758,3001,4,2463,2011,2956,571,208,2866,714,1112,447,1037,1258,2911,2529,3365,289,2275,28,2278,1044,315,1414,43,26,729,2546,1882,1420,255,367,1574,2128,1890,656,3274,3024,2739,2942,3418,2750,401,285,801
|
0.6723269112207332,3.520478778498601,-0.11613860568977677,-0.011824157758994824,0.36404879012622693,0.33969505804727207,-0.41292781072703233,0.03965766766041974,-0.19559772347892793,-1.3451913690083444,1.952786157251336,0.16647131175699767,0.48440969406177936,3.185852181395418,4.991829849894577,4.95230803704758,-0.49658581124515616,-0.6388152651515875,5.796784418092093,-0.3578263417200354,-0.19559772347892793,-0.6100808230827668,0.3883074039088583,1.0105179663695107,-0.5530485515520936,0.290698308478738,0.11606410191198446,0.5082068465574456,0.14131998091565823,0.06523411656369492,-0.5814925595785796,-0.38531114273962846,-1.2475813324366078,0.7413917409113739,-0.2761470099076228,4.602257829733616,-0.2761470099076228,0.14131998091565823,0.6954312126789955,0.013971984461395193,3.9610928617452967,4.7385298944612435,0.290698308478738,-0.38531114273962846,-0.14250621643165773,0.013971984461395193,0.8323417145063771,0.625866314583955,-0.037732006077157064,-0.22232443406475605,-0.14250621643165773,0.33969505804727207,-0.9043423207096438,-0.6388152651515875,-0.46856343097646624,-0.5814925595785796,-1.8242310197178253,-0.46856343097646624,0.5790643592485345,0.764249500072063,0.26605328440668863
| 3,447
|
Adaptive immune response
| 10
| 48
| 2.888719
| 0.003868
|
P10909,P04439,Q9BY67,Q9UQ84,O15400,P10321,P53634,P02786,Q13740,Q07021
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
58,72,175,112,210,83,20,52,154,191
|
210,595,1324,1615,1458,52,1616,72,488,1104,83,2910,58,3151,2525,1624,1255,1177,1468,1259,642,20,2400,1732,1189,191,2719,781,154,1954,2973,2922,2732,2199,829,2784,2620,1658,1430,1661,175,2058,2794,486,278,1520,2146,112
|
0.9885086777190719,0.36404879012622693,0.03965766766041974,-0.06375283048767906,-0.011824157758994824,3.6443989474477476,-0.06375283048767906,3.0380205848750497,0.460522082895191,0.11606410191198446,2.699110242674545,-0.5814925595785796,3.4892019402118737,-0.7552547701634187,-0.38531114273962846,-0.06375283048767906,0.06523411656369492,0.09070253409564899,-0.011824157758994824,0.06523411656369492,0.33969505804727207,4.872739253374519,-0.33047177855621607,-0.08988792448924106,0.09070253409564899,1.0978302599790803,-0.46856343097646624,0.26605328440668863,1.4154814144632912,-0.16899212443771205,-0.6100808230827668,-0.5814925595785796,-0.46856343097646624,-0.2491737041569007,0.24130912809996094,-0.49658581124515616,-0.41292781072703233,-0.06375283048767906,0.013971984461395193,-0.06375283048767906,1.1840120855874656,-0.19559772347892793,-0.49658581124515616,0.48440969406177936,0.7870265918459427,-0.011824157758994824,-0.22232443406475605,2.0100448717400776
| 3,447
|
Cognition
| 11
| 40
| 2.869049
| 0.004117
|
P05067,P17900,Q13641,Q96KQ7,P01130,Q15334,Q92542,P21359,P50897,Q9H0U3,Q7L576
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,4,37,229,73,206,50,220,21,284,223
|
2326,1094,2644,569,73,66,507,1772,4,509,220,2466,1858,2015,2656,1258,816,21,2529,1867,2103,1412,1639,37,206,1801,223,3318,50,229,2045,1074,2741,3384,2136,284,2432,350,2992,285
|
-0.3032458564235702,0.11606410191198446,-0.44067800799054646,0.3883074039088583,3.0214219227005468,3.185852181395418,0.43654311105882554,-0.11613860568977677,5.796784418092093,0.43654311105882554,0.944268201707387,-0.3578263417200354,-0.14250621643165773,-0.19559772347892793,-0.44067800799054646,0.06523411656369492,0.24130912809996094,4.832688203866245,-0.38531114273962846,-0.14250621643165773,-0.22232443406475605,0.013971984461395193,-0.06375283048767906,4.136820106166587,1.032454143437075,-0.11613860568977677,0.944268201707387,-0.9957915972367293,3.736124836573613,0.9220357095144189,-0.19559772347892793,0.14131998091565823,-0.46856343097646624,-1.3451913690083444,-0.22232443406475605,0.764249500072063,-0.33047177855621607,0.6491388771216718,-0.6100808230827668,0.764249500072063
| 3,447
|
Abnormal circulating lipid concentration
| 10
| 78
| 2.854808
| 0.004306
|
O43772,Q15125,Q15392,P01130,P06280,P07602,P38571,Q15904,Q9UBM7,P61916
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
67,68,9,73,12,15,82,54,86,28
|
1156,1027,758,67,2998,3037,538,189,2005,1236,600,73,3180,12,602,15,3079,1773,3376,1172,3084,389,979,1035,2584,981,3334,2712,82,1256,2867,1258,2587,639,2765,3325,1262,676,1552,2659,920,3009,678,1264,28,2664,2345,990,232,612,291,87,930,68,9,2969,344,2543,54,2726,1799,2550,1572,882,2040,621,2365,2428,2850,3203,3172,2750,86,2562,2376,1991,3148,1092
|
0.09070253409564899,0.14131998091565823,0.26605328440668863,3.1532393194800354,-0.6388152651515875,-0.6676978506562085,0.412471861925284,1.0978302599790803,-0.19559772347892793,0.06523411656369492,0.36404879012622693,3.0214219227005468,-0.7847504591189078,5.096383797522485,0.36404879012622693,4.95230803704758,-0.6967305875166148,-0.11613860568977677,-1.3124535957086996,0.09070253409564899,-0.6967305875166148,0.5790643592485345,0.16647131175699767,0.14131998091565823,-0.41292781072703233,0.16647131175699767,-1.057631062572967,-0.46856343097646624,2.733680073850197,0.06523411656369492,-0.5530485515520936,0.06523411656369492,-0.41292781072703233,0.33969505804727207,-0.49658581124515616,-1.0266222601373636,0.06523411656369492,0.3152452291356413,-0.037732006077157064,-0.44067800799054646,0.19151921531853922,-0.6388152651515875,0.3152452291356413,0.06523411656369492,4.602257829733616,-0.44067800799054646,-0.3032458564235702,0.16647131175699767,0.899727495712953,0.36404879012622693,0.7413917409113739,2.5415711073347276,0.19151921531853922,3.120491344892983,5.327333042658442,-0.6100808230827668,0.6491388771216718,-0.38531114273962846,3.613594638576244,-0.46856343097646624,-0.11613860568977677,-0.38531114273962846,-0.037732006077157064,0.21646479318514736,-0.19559772347892793,0.36404879012622693,-0.3032458564235702,-0.33047177855621607,-0.5247469164830378,-0.7847504591189078,-0.7552547701634187,-0.46856343097646624,2.5768641425022323,-0.38531114273962846,-0.3032458564235702,-0.16899212443771205,-0.7259155280154393,0.14131998091565823
| 3,447
|
Arteriosclerosis
| 7
| 16
| 2.850022
| 0.004372
|
P16278,P01130,Q99519,Q13510,P38571,O15118,P61916
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,73,75,43,82,57,28
|
57,567,189,2005,73,3180,35,405,2523,1856,2468,82,28,43,2124,75
|
3.520478778498601,0.3883074039088583,1.0978302599790803,-0.19559772347892793,3.0214219227005468,-0.7847504591189078,4.165756851456292,0.5555333123030265,-0.38531114273962846,-0.14250621643165773,-0.3578263417200354,2.733680073850197,4.602257829733616,3.9610928617452967,-0.22232443406475605,3.0047879739765255
| 3,447
|
Phospholipid transport
| 7
| 16
| 2.841468
| 0.004491
|
Q7Z3C6,P01130,P08183,P33527,Q14108,P61916,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
132,73,113,153,26,28,62
|
73,113,1171,2581,153,1469,28,869,1189,26,994,132,62,3140,271,2375
|
3.0214219227005468,1.9910092185928823,0.09070253409564899,-0.41292781072703233,1.4154814144632912,-0.011824157758994824,4.602257829733616,0.21646479318514736,0.09070253409564899,4.7385298944612435,0.16647131175699767,1.6593829626856886,3.3469394788706537,-0.7259155280154393,0.80972375426467,-0.3032458564235702
| 3,447
|
Ectopic calcification
| 12
| 59
| 2.841316
| 0.004493
|
O75844,P05067,Q15125,O00584,P01130,Q99519,P38571,P04062,P53634,Q9UBM7,Q14739,Q16625
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
189,66,68,6,73,75,82,114,20,86,87,157
|
2997,323,6,1691,757,1452,2641,2389,2998,3037,1029,189,2005,2332,1325,73,3180,2006,3380,114,66,1033,2265,193,263,444,405,2523,3084,1937,2468,82,1256,2959,2659,20,721,3047,678,2402,87,2722,68,2969,157,3163,2296,1747,744,3137,75,1818,3067,1903,2561,2994,86,1228,2701
|
-0.6388152651515875,0.6723269112207332,5.503041426277297,-0.08988792448924106,0.26605328440668863,-0.011824157758994824,-0.44067800799054646,-0.33047177855621607,-0.6388152651515875,-0.6676978506562085,0.14131998091565823,1.0978302599790803,-0.19559772347892793,-0.3032458564235702,0.03965766766041974,3.0214219227005468,-0.7847504591189078,-0.19559772347892793,-1.3451913690083444,1.952786157251336,3.185852181395418,0.14131998091565823,-0.2761470099076228,1.0761096734158762,0.80972375426467,0.5082068465574456,0.5555333123030265,-0.38531114273962846,-0.6967305875166148,-0.16899212443771205,-0.3578263417200354,2.733680073850197,0.06523411656369492,-0.6100808230827668,-0.44067800799054646,4.872739253374519,0.290698308478738,-0.6676978506562085,0.3152452291356413,-0.33047177855621607,2.5415711073347276,-0.46856343097646624,3.120491344892983,-0.6100808230827668,1.3947613988096557,-0.7552547701634187,-0.2761470099076228,-0.08988792448924106,0.290698308478738,-0.7259155280154393,3.0047879739765255,-0.11613860568977677,-0.6676978506562085,-0.14250621643165773,-0.38531114273962846,-0.6100808230827668,2.5768641425022323,0.09070253409564899,-0.44067800799054646
| 3,447
|
Sterol metabolism
| 8
| 29
| 2.83557
| 0.004574
|
Q15125,P01130,Q15392,Q9UBM7,Q14739,O15118,O76062,P61916
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
68,73,9,86,87,57,90,28
|
57,806,2005,90,1844,3077,73,114,670,3369,2958,2712,279,280,28,2966,2822,377,2774,87,68,1483,9,2969,344,431,86,1597,2067
|
3.520478778498601,0.24130912809996094,-0.19559772347892793,2.506111945225677,-0.14250621643165773,-0.6967305875166148,3.0214219227005468,1.952786157251336,0.3152452291356413,-1.2799168876410205,-0.6100808230827668,-0.46856343097646624,0.764249500072063,0.764249500072063,4.602257829733616,-0.6100808230827668,-0.5247469164830378,0.6025084155120215,-0.49658581124515616,2.5415711073347276,3.120491344892983,-0.011824157758994824,5.327333042658442,-0.6100808230827668,0.6491388771216718,0.5319144280730378,2.5768641425022323,-0.037732006077157064,-0.19559772347892793
| 3,447
|
Juvenile onset
| 13
| 44
| 2.829148
| 0.004667
|
P07196,Q8NHS3,P16278,Q8IY17,O14773,Q13510,P06280,P51798,P38571,Q9NR50,P54802,Q9H0U3,O15118
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
310,195,35,367,10,43,12,209,82,351,25,284,57
|
10,57,3408,2646,3180,970,12,763,310,35,1776,490,1332,82,3364,1255,359,2587,1261,2962,1262,1863,3045,209,25,1264,990,1045,1637,43,1479,2031,1737,1134,367,195,1498,3384,284,839,351,3329,1830,1092
|
5.276511437873593,3.520478778498601,-1.6834681362086772,-0.44067800799054646,-0.7847504591189078,0.16647131175699767,5.096383797522485,0.26605328440668863,0.6954312126789955,4.165756851456292,-0.11613860568977677,0.460522082895191,0.03965766766041974,2.733680073850197,-1.2475813324366078,0.06523411656369492,0.625866314583955,-0.41292781072703233,0.06523411656369492,-0.6100808230827668,0.06523411656369492,-0.14250621643165773,-0.6676978506562085,1.0105179663695107,4.7385298944612435,0.06523411656369492,0.16647131175699767,0.14131998091565823,-0.06375283048767906,3.9610928617452967,-0.011824157758994824,-0.19559772347892793,-0.08988792448924106,0.11606410191198446,0.625866314583955,1.0761096734158762,-0.011824157758994824,-1.3451913690083444,0.764249500072063,0.24130912809996094,0.6491388771216718,-1.0266222601373636,-0.11613860568977677,0.14131998091565823
| 3,447
|
Steroid metabolism
| 13
| 31
| 2.81343
| 0.004902
|
Q15800,Q15125,O76062,Q15392,P01130,Q06520,P04062,Q9UBM7,P53602,P54646,O15118,Q14739,P61916
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
344,68,90,9,73,361,114,86,279,280,57,87,28
|
57,806,2005,90,1844,3077,73,114,670,3369,2958,2712,279,280,28,2966,2822,361,377,2774,87,68,1483,9,2969,344,431,3225,86,1597,2067
|
3.520478778498601,0.24130912809996094,-0.19559772347892793,2.506111945225677,-0.14250621643165773,-0.6967305875166148,3.0214219227005468,1.952786157251336,0.3152452291356413,-1.2799168876410205,-0.6100808230827668,-0.46856343097646624,0.764249500072063,0.764249500072063,4.602257829733616,-0.6100808230827668,-0.5247469164830378,0.625866314583955,0.6025084155120215,-0.49658581124515616,2.5415711073347276,3.120491344892983,-0.011824157758994824,5.327333042658442,-0.6100808230827668,0.6491388771216718,0.5319144280730378,-0.8144047886641401,2.5768641425022323,-0.037732006077157064,-0.19559772347892793
| 3,447
|
Diseases of metabolism
| 9
| 45
| 2.809795
| 0.004957
|
P15586,O43505,P16278,P07686,P06865,P10619,O75874,P54802,P10253
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
1,65,35,46,14,47,55,25,59
|
65,1320,3074,3112,55,3398,3235,14,46,59,47,3416,973,1,35,2164,3369,1931,3390,2269,2170,1782,1260,863,2818,3391,1552,719,25,2278,493,1045,3266,3370,2827,2544,2834,1749,793,3413,75,657,1012,3026,2501
|
3.2021083972634283,0.03965766766041974,-0.6967305875166148,-0.7259155280154393,3.5826739461700328,-1.4781383235442953,-0.8442200027409706,4.991829849894577,3.8867761966938223,3.426283702043037,3.8568635354262555,-1.8242310197178253,0.16647131175699767,6.058298299026471,4.165756851456292,-0.2491737041569007,-1.2799168876410205,-0.16899212443771205,-1.411267133335394,-0.2761470099076228,-0.2491737041569007,-0.11613860568977677,0.06523411656369492,0.21646479318514736,-0.5247469164830378,-1.411267133335394,-0.037732006077157064,0.290698308478738,4.7385298944612435,-0.2761470099076228,0.460522082895191,0.14131998091565823,-0.9043423207096438,-1.2799168876410205,-0.5247469164830378,-0.38531114273962846,-0.5247469164830378,-0.08988792448924106,0.26605328440668863,-1.7534654236202036,3.0047879739765255,0.33969505804727207,0.16647131175699767,-0.6388152651515875,-0.3578263417200354
| 3,447
|
Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
| 7
| 36
| 2.80709
| 0.004999
|
P04439,Q9BY67,Q9UQ84,P53634,P02786,P10909,Q07021
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
72,175,112,20,52,58,191
|
210,595,1324,1615,1458,52,1616,72,1104,2910,58,3151,2525,1624,1255,1468,1259,642,20,1189,191,2719,781,1954,2973,2922,2199,829,2620,1430,1661,175,2794,486,1520,112
|
0.9885086777190719,0.36404879012622693,0.03965766766041974,-0.06375283048767906,-0.011824157758994824,3.6443989474477476,-0.06375283048767906,3.0380205848750497,0.11606410191198446,-0.5814925595785796,3.4892019402118737,-0.7552547701634187,-0.38531114273962846,-0.06375283048767906,0.06523411656369492,-0.011824157758994824,0.06523411656369492,0.33969505804727207,4.872739253374519,0.09070253409564899,1.0978302599790803,-0.46856343097646624,0.26605328440668863,-0.16899212443771205,-0.6100808230827668,-0.5814925595785796,-0.2491737041569007,0.24130912809996094,-0.41292781072703233,0.013971984461395193,-0.06375283048767906,1.1840120855874656,-0.49658581124515616,0.48440969406177936,-0.011824157758994824,2.0100448717400776
| 3,447
|
Blood microparticle
| 6
| 19
| 2.80708
| 0.004999
|
Q08380,P04062,P02786,P27105,O00560,P10909
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
16,114,52,53,151,58
|
1913,151,52,114,904,2517,1926,58,2391,263,711,53,2468,2021,1869,1043,16,2197,1590
|
-0.16899212443771205,1.4567344646526146,3.6443989474477476,1.952786157251336,0.19151921531853922,-0.38531114273962846,-0.16899212443771205,3.4892019402118737,-0.33047177855621607,0.80972375426467,0.290698308478738,3.6443989474477476,-0.3578263417200354,-0.19559772347892793,-0.14250621643165773,0.14131998091565823,4.95230803704758,-0.2491737041569007,-0.037732006077157064
| 3,447
|
Glycosphingolipid metabolic process
| 7
| 11
| 2.80519
| 0.005029
|
P16278,P17900,Q99519,P06280,P07686,P06865,P04062
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
35,4,75,12,46,14,114
|
114,12,14,46,35,4,1189,377,875,75,147
|
1.952786157251336,5.096383797522485,4.991829849894577,3.8867761966938223,4.165756851456292,5.796784418092093,0.09070253409564899,0.6025084155120215,0.21646479318514736,3.0047879739765255,1.4977414359476033
| 3,447
|
Antigen processing cross presentation
| 7
| 51
| 2.803869
| 0.005049
|
Q9UBG0,Q9UIQ6,P04439,P49721,P10321,P28072,Q14997
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
64,7,72,91,83,115,155
|
1837,802,2149,2252,2151,898,2381,1383,1026,2572,2258,72,1104,83,444,426,1544,1853,2090,1777,671,1933,389,115,712,2091,1857,2471,2179,1179,91,2343,2963,2819,250,1555,1726,1557,1869,1268,1732,611,1792,155,1346,1434,837,64,7,1685,1522
|
-0.14250621643165773,0.24130912809996094,-0.2491737041569007,-0.2761470099076228,-0.2491737041569007,0.19151921531853922,-0.33047177855621607,0.013971984461395193,0.14131998091565823,-0.41292781072703233,-0.2761470099076228,3.0380205848750497,0.11606410191198446,2.699110242674545,0.5082068465574456,0.5319144280730378,-0.037732006077157064,-0.14250621643165773,-0.22232443406475605,-0.11613860568977677,0.3152452291356413,-0.16899212443771205,0.5790643592485345,1.952786157251336,0.290698308478738,-0.22232443406475605,-0.14250621643165773,-0.3578263417200354,-0.2491737041569007,0.09070253409564899,2.470484601896555,-0.3032458564235702,-0.6100808230827668,-0.5247469164830378,0.8548811891149231,-0.037732006077157064,-0.08988792448924106,-0.037732006077157064,-0.14250621643165773,0.06523411656369492,-0.08988792448924106,0.36404879012622693,-0.11613860568977677,1.4154814144632912,0.03965766766041974,0.013971984461395193,0.24130912809996094,3.282894405814692,5.503041426277297,-0.06375283048767906,-0.011824157758994824
| 3,447
|
Cholesterol metabolism
| 8
| 27
| 2.798985
| 0.005126
|
Q15125,P01130,Q15392,Q9UBM7,Q14739,O15118,O76062,P61916
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
68,73,9,86,87,57,90,28
|
57,806,90,1844,3077,73,114,670,3369,2958,2712,279,280,28,2966,2822,377,2774,87,68,1483,9,2969,344,431,86,1597
|
3.520478778498601,0.24130912809996094,2.506111945225677,-0.14250621643165773,-0.6967305875166148,3.0214219227005468,1.952786157251336,0.3152452291356413,-1.2799168876410205,-0.6100808230827668,-0.46856343097646624,0.764249500072063,0.764249500072063,4.602257829733616,-0.6100808230827668,-0.5247469164830378,0.6025084155120215,-0.49658581124515616,2.5415711073347276,3.120491344892983,-0.011824157758994824,5.327333042658442,-0.6100808230827668,0.6491388771216718,0.5319144280730378,2.5768641425022323,-0.037732006077157064
| 3,447
|
Sarcolemma
| 9
| 26
| 2.791904
| 0.00524
|
P35613,P54289,O75955,P11166,P11279,P19022,P41440,Q92542,P05026
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
160,131,196,263,41,110,359,50,183
|
196,1616,1459,183,507,263,41,1463,110,1173,769,1714,673,160,359,1040,131,1562,2104,1949,408,1051,2284,50,2503,2322
|
1.054317838750862,-0.06375283048767906,-0.011824157758994824,1.1194802025914279,0.43654311105882554,0.80972375426467,4.005368888045156,-0.011824157758994824,2.0100448717400776,0.09070253409564899,0.26605328440668863,-0.08988792448924106,0.3152452291356413,1.3739783978655824,0.625866314583955,0.14131998091565823,1.6593829626856886,-0.037732006077157064,-0.22232443406475605,-0.16899212443771205,0.5555333123030265,0.14131998091565823,-0.2761470099076228,3.736124836573613,-0.3578263417200354,-0.2761470099076228
| 3,447
|
Early endosome membrane
| 11
| 48
| 2.77312
| 0.005552
|
Q86Y82,Q8IV08,P51790,Q9NV96,Q9H4M9,P04439,Q9UEU0,Q15334,O15400,P10321,Q9H223
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
256,0,70,271,270,72,105,206,210,83,252
|
1999,2382,210,1608,1028,597,569,1616,72,83,539,2173,865,70,1407,819,2025,2345,1791,2674,1478,1130,206,1057,937,256,2682,0,3059,695,1071,2044,304,2367,3358,1586,2694,252,1509,270,271,1374,105,2243,2069,1150,959,591
|
-0.19559772347892793,-0.33047177855621607,0.9885086777190719,-0.06375283048767906,0.14131998091565823,0.36404879012622693,0.3883074039088583,-0.06375283048767906,3.0380205848750497,2.699110242674545,0.412471861925284,-0.2491737041569007,0.21646479318514736,3.0545841549970008,0.013971984461395193,0.24130912809996094,-0.19559772347892793,-0.3032458564235702,-0.11613860568977677,-0.44067800799054646,-0.011824157758994824,0.11606410191198446,1.032454143437075,0.14131998091565823,0.19151921531853922,0.8323417145063771,-0.44067800799054646,6.174862566674202,-0.6676978506562085,0.3152452291356413,0.14131998091565823,-0.19559772347892793,0.7184525652536403,-0.3032458564235702,-1.1835028638774374,-0.037732006077157064,-0.44067800799054646,0.8548811891149231,-0.011824157758994824,0.80972375426467,0.80972375426467,0.03965766766041974,2.179150607376429,-0.2491737041569007,-0.19559772347892793,0.11606410191198446,0.19151921531853922,0.3883074039088583
| 3,447
|
Glial cell development
| 8
| 23
| 2.77299
| 0.005554
|
P05067,Q00534,P01130,Q92542,P21359,Q9NR50,P10909,Q07954
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,290,73,50,220,351,58,60
|
757,73,66,488,1537,58,405,220,1035,1261,290,2103,60,1637,2348,1479,2284,50,743,2045,351,1830,798
|
0.26605328440668863,3.0214219227005468,3.185852181395418,0.460522082895191,-0.037732006077157064,3.4892019402118737,0.5555333123030265,0.944268201707387,0.14131998091565823,0.06523411656369492,0.7413917409113739,-0.22232443406475605,3.362871077444676,-0.06375283048767906,-0.3032458564235702,-0.011824157758994824,-0.2761470099076228,3.736124836573613,0.290698308478738,-0.19559772347892793,0.6491388771216718,-0.11613860568977677,0.26605328440668863
| 3,447
|
Ion homeostasis
| 26
| 108
| 2.77222
| 0.005568
|
Q93050,Q8NEW0,P54289,Q8NE01,O75503,P50897,Q92859,Q13642,Q92544,P07686,Q7L0J3,P98194,P02786,Q15904,P05026,Q9HD20,P09601,P05067,P51790,Q15334,Q96PU5,P54709,O14745,Q9BXP2,P0DP25,Q6P4Q7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
257,130,131,135,8,21,23,291,170,46,48,298,52,54,183,187,311,66,70,206,349,221,338,370,104,365
|
2511,897,338,2255,1696,667,1162,3408,8,1236,2259,632,2456,2952,2457,52,1031,2461,1459,183,66,3212,46,488,3116,1104,311,2084,1708,104,2651,707,1394,811,2519,2520,1244,908,1395,1173,1249,978,671,2466,2014,3381,1714,1037,1258,1782,1260,21,641,2474,70,131,221,491,1338,517,2768,3049,298,2103,1412,1949,1639,291,2485,3192,206,54,2828,3162,365,735,48,2838,882,135,791,2037,130,1003,170,23,257,1809,744,1810,349,3167,370,840,1982,187,3443,562,1447,958,533,1307,384,801,3176,591,3372,1912
|
-0.38531114273962846,0.19151921531853922,0.6491388771216718,-0.2761470099076228,-0.08988792448924106,0.3152452291356413,0.09070253409564899,-1.6834681362086772,5.390468925074161,0.06523411656369492,-0.2761470099076228,0.33969505804727207,-0.3578263417200354,-0.6100808230827668,-0.3578263417200354,3.6443989474477476,0.14131998091565823,-0.3578263417200354,-0.011824157758994824,1.1194802025914279,3.185852181395418,-0.8144047886641401,3.8867761966938223,0.460522082895191,-0.7259155280154393,0.11606410191198446,0.6954312126789955,-0.22232443406475605,-0.08988792448924106,2.179150607376429,-0.44067800799054646,0.290698308478738,0.013971984461395193,0.24130912809996094,-0.38531114273962846,-0.38531114273962846,0.06523411656369492,0.19151921531853922,0.013971984461395193,0.09070253409564899,0.06523411656369492,0.16647131175699767,0.3152452291356413,-0.3578263417200354,-0.19559772347892793,-1.3451913690083444,-0.08988792448924106,0.14131998091565823,0.06523411656369492,-0.11613860568977677,0.06523411656369492,4.832688203866245,0.33969505804727207,-0.3578263417200354,3.0545841549970008,1.6593829626856886,0.944268201707387,0.460522082895191,0.03965766766041974,0.43654311105882554,-0.49658581124515616,-0.6676978506562085,0.7184525652536403,-0.22232443406475605,0.013971984461395193,-0.16899212443771205,-0.06375283048767906,0.7413917409113739,-0.3578263417200354,-0.7847504591189078,1.032454143437075,3.613594638576244,-0.5247469164830378,-0.7552547701634187,0.625866314583955,0.290698308478738,3.841866850895795,-0.5247469164830378,0.21646479318514736,1.6393818573898824,0.26605328440668863,-0.19559772347892793,1.6793270618899536,0.16647131175699767,1.247929148925315,4.792456598943272,0.8323417145063771,-0.11613860568977677,0.290698308478738,-0.11613860568977677,0.6491388771216718,-0.7552547701634187,0.625866314583955,0.24130912809996094,-0.16899212443771205,1.1194802025914279,-7.8923316955383385,0.412471861925284,0.013971984461395193,0.19151921531853922,0.43654311105882554,0.06523411656369492,0.6025084155120215,0.26605328440668863,-0.7552547701634187,0.3883074039088583,-1.2799168876410205,-0.14250621643165773
| 3,447
|
Cell adhesion molecules cams
| 8
| 11
| 2.771838
| 0.005574
|
P04439,P19022,P10321,Q92859,Q9Y624,Q13740,Q16625,Q92896
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
72,110,83,23,121,154,157,63
|
72,507,83,2085,110,154,157,23,63,175,121
|
3.0380205848750497,0.43654311105882554,2.699110242674545,-0.22232443406475605,2.0100448717400776,1.4154814144632912,1.3947613988096557,4.792456598943272,3.3469394788706537,1.1840120855874656,1.8368772029414835
| 3,447
|
Diarrhea
| 8
| 76
| 2.770442
| 0.005598
|
P15586,P42892,Q13510,P06280,P07686,P02786,Q15904,P54802
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,5,43,12,46,52,54,25
|
2381,1320,595,2386,760,1325,569,1458,52,2006,3380,2333,12,46,1850,633,1773,1,405,3152,3342,3153,1711,2816,3390,2958,3334,1467,637,82,3364,2867,2959,3283,5,676,1551,3365,25,1181,1472,1628,923,648,429,43,1793,2031,1345,205,2284,2877,54,2726,2287,455,1420,2550,255,2120,3195,1356,1001,2130,2217,1580,2365,1809,3394,1071,3024,1012,1440,1593,2376,1997
|
-0.33047177855621607,0.03965766766041974,0.36404879012622693,-0.33047177855621607,0.26605328440668863,0.03965766766041974,0.3883074039088583,-0.011824157758994824,3.6443989474477476,-0.19559772347892793,-1.3451913690083444,-0.3032458564235702,5.096383797522485,3.8867761966938223,-0.14250621643165773,0.33969505804727207,-0.11613860568977677,6.058298299026471,0.5555333123030265,-0.7552547701634187,-1.0888207132458592,-0.7552547701634187,-0.08988792448924106,-0.5247469164830378,-1.411267133335394,-0.6100808230827668,-1.057631062572967,-0.011824157758994824,0.33969505804727207,2.733680073850197,-1.2475813324366078,-0.5530485515520936,-0.6100808230827668,-0.9346541779980903,5.626549900164905,0.3152452291356413,-0.037732006077157064,-1.2475813324366078,4.7385298944612435,0.09070253409564899,-0.011824157758994824,-0.06375283048767906,0.19151921531853922,0.33969505804727207,0.5319144280730378,3.9610928617452967,-0.11613860568977677,-0.19559772347892793,0.03965766766041974,1.032454143437075,-0.2761470099076228,-0.5530485515520936,3.613594638576244,-0.46856343097646624,-0.2761470099076228,0.5082068465574456,0.013971984461395193,-0.38531114273962846,0.8323417145063771,-0.22232443406475605,-0.7847504591189078,0.03965766766041974,0.16647131175699767,-0.22232443406475605,-0.2491737041569007,-0.037732006077157064,-0.3032458564235702,-0.11613860568977677,-1.411267133335394,0.14131998091565823,-0.6388152651515875,0.16647131175699767,0.013971984461395193,-0.037732006077157064,-0.3032458564235702,-0.16899212443771205
| 3,447
|
Viral life cycle
| 15
| 102
| 2.768
| 0.00564
|
P35613,Q9Y624,P08195,O14786,P01130,P11279,P78310,P29317,P02786,P27105,Q9H1E3,P46934,O15118,Q14108,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
160,121,161,99,73,41,136,178,52,53,181,184,57,26,62
|
2450,1450,1525,99,57,2452,1159,1608,1698,967,2454,1768,567,2457,1923,569,73,52,507,1032,1166,161,905,1239,1926,2391,41,2706,3416,1169,1618,3296,1619,539,3004,2464,53,178,2525,160,2093,1178,2173,184,2180,641,2273,204,2275,3047,514,1265,1339,136,1561,2669,315,1343,2402,925,2917,1638,2189,2403,26,1875,873,2410,2678,343,650,1737,2489,787,2292,2885,62,1208,3060,1069,1071,2303,3358,2499,181,415,435,1515,797,2630,2374,2375,3109,3227,3229,754,3032,285,502,121,2637,2903
|
-0.3578263417200354,-0.011824157758994824,-0.037732006077157064,2.308023112336245,3.520478778498601,-0.3578263417200354,0.09070253409564899,-0.06375283048767906,-0.08988792448924106,0.16647131175699767,-0.3578263417200354,-0.11613860568977677,0.3883074039088583,-0.3578263417200354,-0.16899212443771205,0.3883074039088583,3.0214219227005468,3.6443989474477476,0.43654311105882554,0.14131998091565823,0.09070253409564899,1.3531319100008414,0.19151921531853922,0.06523411656369492,-0.16899212443771205,-0.33047177855621607,4.005368888045156,-0.46856343097646624,-1.8242310197178253,0.09070253409564899,-0.06375283048767906,-0.9651364301489054,-0.06375283048767906,0.412471861925284,-0.6388152651515875,-0.3578263417200354,3.6443989474477476,1.162570531532433,-0.38531114273962846,1.3739783978655824,-0.22232443406475605,0.09070253409564899,-0.2491737041569007,1.1194802025914279,-0.2491737041569007,0.33969505804727207,-0.2761470099076228,1.032454143437075,-0.2761470099076228,-0.6676978506562085,0.43654311105882554,0.06523411656369492,0.03965766766041974,1.6193233192302938,-0.037732006077157064,-0.44067800799054646,0.6954312126789955,0.03965766766041974,-0.33047177855621607,0.19151921531853922,-0.5814925595785796,-0.06375283048767906,-0.2491737041569007,-0.33047177855621607,4.7385298944612435,-0.14250621643165773,0.21646479318514736,-0.33047177855621607,-0.44067800799054646,0.6491388771216718,0.33969505804727207,-0.08988792448924106,-0.3578263417200354,0.26605328440668863,-0.2761470099076228,-0.5530485515520936,3.3469394788706537,0.09070253409564899,-0.6676978506562085,0.14131998091565823,0.14131998091565823,-0.2761470099076228,-1.1835028638774374,-0.3578263417200354,1.1410600971660143,0.5555333123030265,0.5319144280730378,-0.011824157758994824,0.26605328440668863,-0.41292781072703233,-0.3032458564235702,-0.3032458564235702,-0.6967305875166148,-0.8144047886641401,-0.8144047886641401,0.290698308478738,-0.6388152651515875,0.764249500072063,0.460522082895191,1.8368772029414835,-0.41292781072703233,-0.5530485515520936
| 3,447
|
Metalloprotease
| 7
| 27
| 2.766643
| 0.005664
|
O75844,P42892,O75976,Q9UIQ6,O43847,Q9BYT8,P55786
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
189,5,39,7,246,186,123
|
2151,246,2757,189,39,2862,1461,2652,1618,5,1041,123,2290,2732,736,1292,1584,2892,1975,186,2059,2311,1218,1907,278,7,3176
|
-0.2491737041569007,0.8548811891149231,-0.49658581124515616,1.0978302599790803,4.107784534784334,-0.5530485515520936,-0.011824157758994824,-0.44067800799054646,-0.06375283048767906,5.626549900164905,0.14131998091565823,1.7782070510206058,-0.2761470099076228,-0.46856343097646624,0.290698308478738,0.06523411656369492,-0.037732006077157064,-0.5530485515520936,-0.16899212443771205,1.1194802025914279,-0.19559772347892793,-0.2761470099076228,0.09070253409564899,-0.14250621643165773,0.7870265918459427,5.503041426277297,-0.7552547701634187
| 3,447
|
Regulation of system process
| 14
| 69
| 2.761025
| 0.005762
|
O75844,Q9UQB8,P05067,P54289,P42892,Q14126,P78310,P0DP25,Q15334,P04062,P53634,P05026,P10253,Q86TU7
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
189,97,66,131,5,137,136,104,206,114,20,183,59,158
|
338,2454,2079,1770,189,2259,2080,2456,2645,1458,3180,114,2461,1459,183,66,2647,3116,236,2084,104,59,2159,2086,1928,1710,811,2519,2520,908,2393,1173,2336,1714,1858,5,1403,2529,20,131,1118,1944,517,136,3049,3409,576,2670,315,1562,1413,408,518,2483,1478,137,1127,206,3095,158,1074,1981,1982,562,2799,798,97,3363,591
|
0.6491388771216718,-0.3578263417200354,-0.22232443406475605,-0.11613860568977677,1.0978302599790803,-0.2761470099076228,-0.22232443406475605,-0.3578263417200354,-0.44067800799054646,-0.011824157758994824,-0.7847504591189078,1.952786157251336,-0.3578263417200354,-0.011824157758994824,1.1194802025914279,3.185852181395418,-0.44067800799054646,-0.7259155280154393,0.8773428842135269,-0.22232443406475605,2.179150607376429,3.426283702043037,-0.2491737041569007,-0.22232443406475605,-0.16899212443771205,-0.08988792448924106,0.24130912809996094,-0.38531114273962846,-0.38531114273962846,0.19151921531853922,-0.33047177855621607,0.09070253409564899,-0.3032458564235702,-0.08988792448924106,-0.14250621643165773,5.626549900164905,0.013971984461395193,-0.38531114273962846,4.872739253374519,1.6593829626856886,0.11606410191198446,-0.16899212443771205,0.43654311105882554,1.6193233192302938,-0.6676978506562085,-1.7183704220896816,0.3883074039088583,-0.44067800799054646,0.6954312126789955,-0.037732006077157064,0.013971984461395193,0.5555333123030265,0.43654311105882554,-0.3578263417200354,-0.011824157758994824,1.6193233192302938,0.11606410191198446,1.032454143437075,-0.6967305875166148,1.3947613988096557,0.14131998091565823,-0.16899212443771205,-0.16899212443771205,0.412471861925284,-0.49658581124515616,0.26605328440668863,2.3444338300023935,-1.2154443741784,0.3883074039088583
| 3,447
|
Abnormal oral mucosa morphology
| 8
| 66
| 2.75446
| 0.005879
|
P16278,Q15392,Q99519,P53634,Q9UBM7,Q14739,Q14108,O00754
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,9,75,20,86,87,26,30
|
2511,30,758,2641,2386,3037,2005,1102,2332,114,1033,193,1710,35,2463,1543,2584,1255,2177,639,2018,20,1472,2664,868,2345,923,646,493,1189,1791,3156,2919,1793,26,87,2108,930,2284,9,3396,3343,433,935,2200,2120,3195,1000,525,883,1212,2691,75,1818,2057,2991,3067,2561,278,86,2562,3352,1307,962,1997,3148
|
-0.38531114273962846,4.49169826573745,0.26605328440668863,-0.44067800799054646,-0.33047177855621607,-0.6676978506562085,-0.19559772347892793,0.11606410191198446,-0.3032458564235702,1.952786157251336,0.14131998091565823,1.0761096734158762,-0.08988792448924106,4.165756851456292,-0.3578263417200354,-0.037732006077157064,-0.41292781072703233,0.06523411656369492,-0.2491737041569007,0.33969505804727207,-0.19559772347892793,4.872739253374519,-0.011824157758994824,-0.44067800799054646,0.21646479318514736,-0.3032458564235702,0.19151921531853922,0.33969505804727207,0.460522082895191,0.09070253409564899,-0.11613860568977677,-0.7552547701634187,-0.5814925595785796,-0.11613860568977677,4.7385298944612435,2.5415711073347276,-0.22232443406475605,0.19151921531853922,-0.2761470099076228,5.327333042658442,-1.4446036602064072,-1.0888207132458592,0.5319144280730378,0.19151921531853922,-0.2491737041569007,-0.22232443406475605,-0.7847504591189078,0.16647131175699767,0.43654311105882554,0.21646479318514736,0.09070253409564899,-0.44067800799054646,3.0047879739765255,-0.11613860568977677,-0.19559772347892793,-0.6100808230827668,-0.6676978506562085,-0.38531114273962846,0.7870265918459427,2.5768641425022323,-0.38531114273962846,-1.1201939880656602,0.06523411656369492,0.19151921531853922,-0.16899212443771205,-0.7259155280154393
| 3,447
|
Apical part of cell
| 22
| 59
| 2.741938
| 0.006108
|
Q9NV96,P11166,P30825,P33527,Q16625,Q12959,P08195,Q8NCM8,P05026,P05067,O75955,P51790,P01130,P36543,P41208,P54709,O14745,P19022,P41440,P55011,P08183,Q13131
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
271,263,140,153,157,408,161,552,183,66,196,70,73,447,216,221,338,110,359,491,113,377
|
2075,338,3331,1917,759,196,73,1616,1459,183,66,113,161,1706,905,263,1927,708,110,908,1543,1930,1173,711,140,153,1937,673,447,1467,1037,216,359,70,1942,221,491,1265,1338,1734,408,377,2189,1874,549,1347,687,157,3164,552,1975,1303,955,271,751,3389,2947,3372,1912
|
-0.22232443406475605,0.6491388771216718,-1.057631062572967,-0.16899212443771205,0.26605328440668863,1.054317838750862,3.0214219227005468,-0.06375283048767906,-0.011824157758994824,1.1194802025914279,3.185852181395418,1.9910092185928823,1.3531319100008414,-0.08988792448924106,0.19151921531853922,0.80972375426467,-0.16899212443771205,0.290698308478738,2.0100448717400776,0.19151921531853922,-0.037732006077157064,-0.16899212443771205,0.09070253409564899,0.290698308478738,1.5790322112008415,1.4154814144632912,-0.16899212443771205,0.3152452291356413,0.5082068465574456,-0.011824157758994824,0.14131998091565823,0.9664256387623936,0.625866314583955,3.0545841549970008,-0.16899212443771205,0.944268201707387,0.460522082895191,0.06523411656369492,0.03965766766041974,-0.08988792448924106,0.5555333123030265,0.6025084155120215,-0.2491737041569007,-0.14250621643165773,0.412471861925284,0.03965766766041974,0.3152452291356413,1.3947613988096557,-0.7552547701634187,0.412471861925284,-0.16899212443771205,0.06523411656369492,0.19151921531853922,0.80972375426467,0.290698308478738,-1.3781294605421666,-0.5814925595785796,-1.2799168876410205,-0.14250621643165773
| 3,447
|
Positive regulation of response to external stimulus
| 18
| 61
| 2.741469
| 0.006117
|
Q08722,P05067,O14786,P14174,Q13641,Q99735,P01130,P11279,Q9BY67,O00429,P61086,P26583,P53634,O94813,P07948,P33527,Q07021,P51809
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
194,66,99,404,37,369,73,41,175,323,492,297,20,84,488,153,191,481
|
323,99,2381,1695,84,2080,2261,1847,73,2460,66,1168,488,1104,41,2577,1617,404,2519,2393,1465,297,1249,671,2466,1250,153,540,2911,481,20,492,1730,868,191,2671,194,825,1793,37,2722,1735,2411,1954,994,876,2885,790,791,739,524,2690,2555,3024,369,3063,175,1982,2313,3356,1681
|
0.6723269112207332,2.308023112336245,-0.33047177855621607,-0.08988792448924106,2.6294966021683392,-0.22232443406475605,-0.2761470099076228,-0.14250621643165773,3.0214219227005468,-0.3578263417200354,3.185852181395418,0.09070253409564899,0.460522082895191,0.11606410191198446,4.005368888045156,-0.41292781072703233,-0.06375283048767906,0.5555333123030265,-0.38531114273962846,-0.33047177855621607,-0.011824157758994824,0.7184525652536403,0.06523411656369492,0.3152452291356413,-0.3578263417200354,0.06523411656369492,1.4154814144632912,0.412471861925284,-0.5814925595785796,0.48440969406177936,4.872739253374519,0.460522082895191,-0.08988792448924106,0.21646479318514736,1.0978302599790803,-0.44067800799054646,1.0761096734158762,0.24130912809996094,-0.11613860568977677,4.136820106166587,-0.46856343097646624,-0.08988792448924106,-0.33047177855621607,-0.16899212443771205,0.16647131175699767,0.21646479318514736,-0.5530485515520936,0.26605328440668863,0.26605328440668863,0.290698308478738,0.43654311105882554,-0.44067800799054646,-0.38531114273962846,-0.6388152651515875,0.625866314583955,-0.6676978506562085,1.1840120855874656,-0.16899212443771205,-0.2761470099076228,-1.1517537324747553,-0.06375283048767906
| 3,447
|
Receptor
| 7
| 32
| 2.735684
| 0.006225
|
Q9UQB8,Q13641,A6NIH7,P20645,Q14108,Q8WTV0,P11717
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
97,37,108,142,26,62,31
|
108,1231,1695,2998,1455,1922,507,31,142,3364,914,1786,1791,408,37,26,874,164,2730,1489,735,62,1208,1291,3138,950,2233,3329,259,2439,3147,97
|
2.0479661553147435,0.06523411656369492,-0.08988792448924106,-0.6388152651515875,-0.011824157758994824,-0.16899212443771205,0.43654311105882554,4.393795198319631,1.5587987614920094,-1.2475813324366078,0.19151921531853922,-0.11613860568977677,-0.11613860568977677,0.5555333123030265,4.136820106166587,4.7385298944612435,0.21646479318514736,1.3322214270954764,-0.46856343097646624,-0.011824157758994824,0.290698308478738,3.3469394788706537,0.09070253409564899,0.06523411656369492,-0.7259155280154393,0.19151921531853922,-0.2491737041569007,-1.0266222601373636,0.8323417145063771,-0.33047177855621607,-0.7259155280154393,2.3444338300023935
| 3,447
|
Abnormal tongue morphology
| 9
| 75
| 2.734335
| 0.006251
|
P16278,P04066,Q99519,P07686,O43924,Q9UBM7,P10253,Q5SZK8,O00754
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,11,75,46,81,86,59,92,30
|
1155,1606,3177,30,2253,1383,1384,758,81,1162,3037,538,189,1844,3180,11,310,46,1034,59,634,35,2463,1543,2393,2011,2466,2584,1178,3087,983,2528,2100,274,2664,2666,1474,1411,1634,990,1412,1791,2028,2402,3015,1794,453,930,519,3396,92,433,935,828,3417,107,552,1809,744,1505,2691,75,2220,1974,1981,497,1015,1986,2794,2629,86,2562,3148,1091,2903
|
0.09070253409564899,-0.06375283048767906,-0.7847504591189078,4.49169826573745,-0.2761470099076228,0.013971984461395193,0.013971984461395193,0.26605328440668863,2.750906555502383,0.09070253409564899,-0.6676978506562085,0.412471861925284,1.0978302599790803,-0.14250621643165773,-0.7847504591189078,5.238210069294953,0.6954312126789955,3.8867761966938223,0.14131998091565823,3.426283702043037,0.33969505804727207,4.165756851456292,-0.3578263417200354,-0.037732006077157064,-0.33047177855621607,-0.19559772347892793,-0.3578263417200354,-0.41292781072703233,0.09070253409564899,-0.6967305875166148,0.16647131175699767,-0.38531114273962846,-0.22232443406475605,0.7870265918459427,-0.44067800799054646,-0.44067800799054646,-0.011824157758994824,0.013971984461395193,-0.06375283048767906,0.16647131175699767,0.013971984461395193,-0.11613860568977677,-0.19559772347892793,-0.33047177855621607,-0.6388152651515875,-0.11613860568977677,0.5082068465574456,0.19151921531853922,0.43654311105882554,-1.4446036602064072,2.4526072090297046,0.5319144280730378,0.19151921531853922,0.24130912809996094,-1.8242310197178253,2.104478107048702,0.412471861925284,-0.11613860568977677,0.290698308478738,-0.011824157758994824,-0.44067800799054646,3.0047879739765255,-0.2491737041569007,-0.16899212443771205,-0.16899212443771205,0.460522082895191,0.16647131175699767,-0.16899212443771205,-0.49658581124515616,-0.41292781072703233,2.5768641425022323,-0.38531114273962846,-0.7259155280154393,0.14131998091565823,-0.5530485515520936
| 3,447
|
Abnormality of the tongue
| 10
| 96
| 2.725735
| 0.006416
|
P16278,P04066,Q13510,Q99519,P07686,O43924,Q9UBM7,P10253,Q5SZK8,O00754
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
35,11,43,75,46,81,86,59,92,30
|
1155,1606,3177,30,2253,1383,1384,758,81,1162,2998,3037,538,189,1844,760,387,3180,11,474,310,46,1034,59,634,35,2463,1543,2393,2011,977,2466,2584,1256,1178,3087,983,2018,288,2528,2275,678,2100,274,2664,2666,1474,1411,1634,990,1412,1189,1791,2028,3156,2402,3015,43,1794,453,930,519,2353,3396,92,433,935,828,3417,107,552,2041,1809,744,1505,2691,75,2220,1974,3404,463,1981,2230,497,1982,1015,1986,2794,2629,1906,748,86,2562,3148,1091,2903
|
0.09070253409564899,-0.06375283048767906,-0.7847504591189078,4.49169826573745,-0.2761470099076228,0.013971984461395193,0.013971984461395193,0.26605328440668863,2.750906555502383,0.09070253409564899,-0.6388152651515875,-0.6676978506562085,0.412471861925284,1.0978302599790803,-0.14250621643165773,0.26605328440668863,0.5790643592485345,-0.7847504591189078,5.238210069294953,0.48440969406177936,0.6954312126789955,3.8867761966938223,0.14131998091565823,3.426283702043037,0.33969505804727207,4.165756851456292,-0.3578263417200354,-0.037732006077157064,-0.33047177855621607,-0.19559772347892793,0.16647131175699767,-0.3578263417200354,-0.41292781072703233,0.06523411656369492,0.09070253409564899,-0.6967305875166148,0.16647131175699767,-0.19559772347892793,0.7413917409113739,-0.38531114273962846,-0.2761470099076228,0.3152452291356413,-0.22232443406475605,0.7870265918459427,-0.44067800799054646,-0.44067800799054646,-0.011824157758994824,0.013971984461395193,-0.06375283048767906,0.16647131175699767,0.013971984461395193,0.09070253409564899,-0.11613860568977677,-0.19559772347892793,-0.7552547701634187,-0.33047177855621607,-0.6388152651515875,3.9610928617452967,-0.11613860568977677,0.5082068465574456,0.19151921531853922,0.43654311105882554,-0.3032458564235702,-1.4446036602064072,2.4526072090297046,0.5319144280730378,0.19151921531853922,0.24130912809996094,-1.8242310197178253,2.104478107048702,0.412471861925284,-0.19559772347892793,-0.11613860568977677,0.290698308478738,-0.011824157758994824,-0.44067800799054646,3.0047879739765255,-0.2491737041569007,-0.16899212443771205,-1.5457992357453925,0.5082068465574456,-0.16899212443771205,-0.2491737041569007,0.460522082895191,-0.16899212443771205,0.16647131175699767,-0.16899212443771205,-0.49658581124515616,-0.41292781072703233,-0.14250621643165773,0.290698308478738,2.5768641425022323,-0.38531114273962846,-0.7259155280154393,0.14131998091565823,-0.5530485515520936
| 3,447
|
Monovalent inorganic cation homeostasis
| 9
| 28
| 2.71868
| 0.006554
|
Q93050,P51790,O75503,Q92544,P50897,Q15904,P05026,P54709,Q96PU5
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
257,70,8,170,21,54,183,221,349
|
8,2461,1459,183,3212,1708,1249,2466,21,641,70,221,491,1338,1412,54,882,170,257,744,349,370,1447,958,801,591,3372,1912
|
5.390468925074161,-0.3578263417200354,-0.011824157758994824,1.1194802025914279,-0.8144047886641401,-0.08988792448924106,0.06523411656369492,-0.3578263417200354,4.832688203866245,0.33969505804727207,3.0545841549970008,0.944268201707387,0.460522082895191,0.03965766766041974,0.013971984461395193,3.613594638576244,0.21646479318514736,1.247929148925315,0.8323417145063771,0.290698308478738,0.6491388771216718,0.625866314583955,0.013971984461395193,0.19151921531853922,0.26605328440668863,0.3883074039088583,-1.2799168876410205,-0.14250621643165773
| 3,447
|
Response to elevated platelet cytosolic ca2
| 7
| 33
| 2.718604
| 0.006556
|
P05067,Q8NBM8,Q9UEU0,O43852,Q08380,P07602,P10909
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
66,134,105,77,16,15,58
|
2075,1027,77,2386,1613,2516,66,15,2517,58,1106,2519,1463,2393,1620,2094,573,2187,16,2543,1881,1001,134,3426,213,2558,1516,486,2750,105,2067,3293,1229
|
-0.22232443406475605,0.14131998091565823,2.9042321491780596,-0.33047177855621607,-0.06375283048767906,-0.38531114273962846,3.185852181395418,4.95230803704758,-0.38531114273962846,3.4892019402118737,0.11606410191198446,-0.38531114273962846,-0.011824157758994824,-0.33047177855621607,-0.06375283048767906,-0.22232443406475605,0.3883074039088583,-0.2491737041569007,4.95230803704758,-0.38531114273962846,-0.14250621643165773,0.16647131175699767,1.6393818573898824,-2.0410879278253518,0.9885086777190719,-0.38531114273962846,-0.011824157758994824,0.48440969406177936,-0.46856343097646624,2.179150607376429,-0.19559772347892793,-0.9346541779980903,0.09070253409564899
| 3,447
|
Regulation of blood circulation
| 8
| 29
| 2.709166
| 0.006745
|
O75844,P54289,P42892,Q14126,P78310,P0DP25,P05026,P10253
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
189,131,5,137,136,104,183,59
|
2079,189,2259,2645,1458,1459,183,236,104,59,1928,1710,811,2519,2520,908,2393,1173,1714,5,131,1944,517,136,3049,408,137,3095,562
|
-0.22232443406475605,1.0978302599790803,-0.2761470099076228,-0.44067800799054646,-0.011824157758994824,-0.011824157758994824,1.1194802025914279,0.8773428842135269,2.179150607376429,3.426283702043037,-0.16899212443771205,-0.08988792448924106,0.24130912809996094,-0.38531114273962846,-0.38531114273962846,0.19151921531853922,-0.33047177855621607,0.09070253409564899,-0.08988792448924106,5.626549900164905,1.6593829626856886,-0.16899212443771205,0.43654311105882554,1.6193233192302938,-0.6676978506562085,0.5555333123030265,1.6193233192302938,-0.6967305875166148,0.412471861925284
| 3,447
|
Organophosphate ester transport
| 8
| 31
| 2.708777
| 0.006753
|
Q08722,Q7Z3C6,P01130,P08183,P33527,Q14108,P61916,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
194,132,73,113,153,26,28,62
|
3072,73,2334,113,508,2650,1171,2581,153,359,1469,28,869,1189,194,26,994,936,3017,828,132,2204,584,2423,62,1297,3140,2939,1302,271,2375
|
-0.6967305875166148,3.0214219227005468,-0.3032458564235702,1.9910092185928823,0.43654311105882554,-0.44067800799054646,0.09070253409564899,-0.41292781072703233,1.4154814144632912,0.625866314583955,-0.011824157758994824,4.602257829733616,0.21646479318514736,0.09070253409564899,1.0761096734158762,4.7385298944612435,0.16647131175699767,0.19151921531853922,-0.6388152651515875,0.24130912809996094,1.6593829626856886,-0.2491737041569007,0.3883074039088583,-0.33047177855621607,3.3469394788706537,0.06523411656369492,-0.7259155280154393,-0.5814925595785796,0.06523411656369492,0.80972375426467,-0.3032458564235702
| 3,447
|
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps
| 6
| 18
| 2.707313
| 0.006783
|
Q02818,P05067,O43852,P19022,O43493,Q9BTY2
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
95,66,77,110,18,24
|
18,77,632,66,1166,146,1107,1394,110,2580,95,2027,330,1129,409,3343,3018,24
|
4.925863408400397,2.9042321491780596,0.33969505804727207,3.185852181395418,0.09070253409564899,1.4977414359476033,0.11606410191198446,0.013971984461395193,2.0100448717400776,-0.41292781072703233,2.3625723141377883,-0.19559772347892793,0.6723269112207332,0.11606410191198446,0.5555333123030265,-1.0888207132458592,-0.6388152651515875,4.752042300962526
| 3,447
|
Endosome
| 58
| 225
| 2.703584
| 0.00686
|
Q8IV08,Q86Y82,Q93050,Q7Z3C6,P42892,Q9NV96,Q9UIQ6,Q9H4M9,Q2M389,O14773,P20645,P07602,Q5VW38,O43493,Q99805,Q14108,Q9UQN3,P11717,P35613,Q7Z6M1,Q15286,P11279,Q13510,Q92544,Q99523,Q9UID3,Q96PE3,Q92542,P02786,Q9BRX9,Q15904,Q9Y2Q5,Q15012,O15118,Q9UNK0,Q07954,Q9UBB6,P05067,P10644,O75955,Q8IY95,P51790,O00461,P04439,P01130,Q15334,O15400,P10321,Q96PU5,Q8WUH2,Q9BRK5,O14786,Q96A57,Q9UEU0,P41440,P40818,Q6IAA8,Q9H223
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,256,257,132,5,271,7,270,268,10,142,15,144,18,147,26,285,31,160,33,292,41,43,170,45,307,304,50,52,180,54,322,56,57,321,60,192,66,193,196,331,70,71,72,73,206,210,83,349,218,89,99,234,105,359,358,238,252
|
1999,71,897,10,99,1763,2382,2001,57,702,1157,210,372,1318,18,1695,1917,1608,1099,1028,1162,1385,597,3074,1768,2643,196,2155,1455,2862,1922,569,73,52,1616,72,66,507,2462,15,3116,1104,357,83,193,2910,2391,41,31,707,708,2522,539,142,977,2166,2167,1249,978,2466,2338,2091,1251,606,1035,3213,2525,160,447,358,359,2173,1258,5,1863,865,641,3044,70,481,721,2964,1407,2475,819,2662,1338,1944,2025,1339,987,867,1730,778,1789,1121,2345,2346,1189,60,2280,1791,450,1639,43,1793,2674,1478,2406,26,549,1796,2676,1563,56,1196,1130,292,206,993,54,784,1954,268,2114,1569,144,1054,238,3193,1055,1882,132,1057,937,33,256,2682,2491,0,2837,331,1494,3100,3059,218,1208,3060,50,170,695,257,2783,234,744,1139,1295,3306,1069,1071,2044,304,349,656,1011,2367,45,1814,147,3358,1586,1753,89,180,795,3138,3444,465,2558,1979,2694,1439,2058,252,1509,839,2308,3328,270,435,1595,841,271,797,1517,3418,2750,2630,3109,1374,2320,192,1989,105,1148,307,7,2146,2243,2801,2069,2322,1150,754,847,959,321,285,800,322,502,801,2947,591,3368
|
-0.19559772347892793,3.0380205848750497,0.19151921531853922,5.276511437873593,2.308023112336245,-0.11613860568977677,-0.33047177855621607,-0.19559772347892793,3.520478778498601,0.290698308478738,0.09070253409564899,0.9885086777190719,0.6025084155120215,0.03965766766041974,4.925863408400397,-0.08988792448924106,-0.16899212443771205,-0.06375283048767906,0.11606410191198446,0.14131998091565823,0.09070253409564899,0.013971984461395193,0.36404879012622693,-0.6967305875166148,-0.11613860568977677,-0.44067800799054646,1.054317838750862,-0.2491737041569007,-0.011824157758994824,-0.5530485515520936,-0.16899212443771205,0.3883074039088583,3.0214219227005468,3.6443989474477476,-0.06375283048767906,3.0380205848750497,3.185852181395418,0.43654311105882554,-0.3578263417200354,4.95230803704758,-0.7259155280154393,0.11606410191198446,0.625866314583955,2.699110242674545,1.0761096734158762,-0.5814925595785796,-0.33047177855621607,4.005368888045156,4.393795198319631,0.290698308478738,0.290698308478738,-0.38531114273962846,0.412471861925284,1.5587987614920094,0.16647131175699767,-0.2491737041569007,-0.2491737041569007,0.06523411656369492,0.16647131175699767,-0.3578263417200354,-0.3032458564235702,-0.22232443406475605,0.06523411656369492,0.36404879012622693,0.14131998091565823,-0.8144047886641401,-0.38531114273962846,1.3739783978655824,0.5082068465574456,0.625866314583955,0.625866314583955,-0.2491737041569007,0.06523411656369492,5.626549900164905,-0.14250621643165773,0.21646479318514736,0.33969505804727207,-0.6676978506562085,3.0545841549970008,0.48440969406177936,0.290698308478738,-0.6100808230827668,0.013971984461395193,-0.3578263417200354,0.24130912809996094,-0.44067800799054646,0.03965766766041974,-0.16899212443771205,-0.19559772347892793,0.03965766766041974,0.16647131175699767,0.21646479318514736,-0.08988792448924106,0.26605328440668863,-0.11613860568977677,0.11606410191198446,-0.3032458564235702,-0.3032458564235702,0.09070253409564899,3.362871077444676,-0.2761470099076228,-0.11613860568977677,0.5082068465574456,-0.06375283048767906,3.9610928617452967,-0.11613860568977677,-0.44067800799054646,-0.011824157758994824,-0.33047177855621607,4.7385298944612435,0.412471861925284,-0.11613860568977677,-0.44067800799054646,-0.037732006077157064,3.55163571681315,0.09070253409564899,0.11606410191198446,0.7413917409113739,1.032454143437075,0.16647131175699767,3.613594638576244,0.26605328440668863,-0.16899212443771205,0.80972375426467,-0.22232443406475605,-0.037732006077157064,1.5181538302974797,0.14131998091565823,0.8773428842135269,-0.7847504591189078,0.14131998091565823,-0.14250621643165773,1.6593829626856886,0.14131998091565823,0.19151921531853922,4.266269685759162,0.8323417145063771,-0.44067800799054646,-0.3578263417200354,6.174862566674202,-0.5247469164830378,0.6723269112207332,-0.011824157758994824,-0.6967305875166148,-0.6676978506562085,0.9664256387623936,0.09070253409564899,-0.6676978506562085,3.736124836573613,1.247929148925315,0.3152452291356413,0.8323417145063771,-0.49658581124515616,0.899727495712953,0.290698308478738,0.11606410191198446,0.06523411656369492,-0.9651364301489054,0.14131998091565823,0.14131998091565823,-0.19559772347892793,0.7184525652536403,0.6491388771216718,0.33969505804727207,0.16647131175699767,-0.3032458564235702,3.9016924241886017,-0.11613860568977677,1.4977414359476033,-1.1835028638774374,-0.037732006077157064,-0.08988792448924106,2.5415711073347276,1.1410600971660143,0.26605328440668863,-0.7259155280154393,-8.760220971245422,0.5082068465574456,-0.38531114273962846,-0.16899212443771205,-0.44067800799054646,0.013971984461395193,-0.19559772347892793,0.8548811891149231,-0.011824157758994824,0.24130912809996094,-0.2761470099076228,-1.0266222601373636,0.80972375426467,0.5319144280730378,-0.037732006077157064,0.24130912809996094,0.80972375426467,0.26605328440668863,-0.011824157758994824,-1.8242310197178253,-0.46856343097646624,-0.41292781072703233,-0.6967305875166148,0.03965766766041974,-0.2761470099076228,1.0978302599790803,-0.16899212443771205,2.179150607376429,0.11606410191198446,0.7184525652536403,5.503041426277297,-0.22232443406475605,-0.2491737041569007,-0.49658581124515616,-0.19559772347892793,-0.2761470099076228,0.11606410191198446,0.290698308478738,0.24130912809996094,0.19151921531853922,0.6954312126789955,0.764249500072063,0.26605328440668863,0.6954312126789955,0.460522082895191,0.26605328440668863,-0.5814925595785796,0.3883074039088583,-1.2475813324366078
| 3,447
|
Cellular monovalent inorganic cation homeostasis
| 7
| 25
| 2.70004
| 0.006933
|
P51790,O75503,Q92544,P50897,Q15904,P05026,P54709
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
70,8,170,21,54,183,221
|
8,1459,183,3212,1708,1249,2466,21,641,70,221,491,1338,1412,54,882,170,257,744,349,1447,958,801,3372,1912
|
5.390468925074161,-0.011824157758994824,1.1194802025914279,-0.8144047886641401,-0.08988792448924106,0.06523411656369492,-0.3578263417200354,4.832688203866245,0.33969505804727207,3.0545841549970008,0.944268201707387,0.460522082895191,0.03965766766041974,0.013971984461395193,3.613594638576244,0.21646479318514736,1.247929148925315,0.8323417145063771,0.290698308478738,0.6491388771216718,0.013971984461395193,0.19151921531853922,0.26605328440668863,-1.2799168876410205,-0.14250621643165773
| 3,447
|
Carbohydrate metabolic process
| 23
| 148
| 2.69637
| 0.00701
|
P17900,P04066,P06280,P06865,O60476,Q9BTY2,Q14108,O00754,P08195,P16278,Q15185,P07686,O75874,Q9BYT8,P10253,O75844,O43505,P05067,Q99519,Q9NX62,Q8NBZ7,Q7LGA3,P48735
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
4,11,12,14,149,24,26,30,161,35,169,46,55,186,59,189,65,66,75,94,106,107,111
|
2857,2380,30,3279,593,1607,703,2327,65,149,1534,3112,2004,3211,1770,189,55,1389,2262,1922,2908,2646,2459,11,2516,1703,2333,66,3078,12,2647,602,1772,14,2264,46,161,1706,1925,706,2335,59,3001,263,2955,1105,1773,2086,3416,973,1927,1709,1108,35,1541,489,4,1464,2579,3441,1035,3390,981,1716,2269,2170,1255,1401,3249,2174,862,2096,1782,111,2818,1862,2962,676,1552,2529,1180,2766,3007,314,280,1943,3010,2820,2477,2531,3049,1871,1121,2667,2871,576,1273,2345,2596,2278,779,2028,782,377,1478,3370,26,2538,2827,2599,3130,1952,169,1737,1485,430,2195,1798,380,734,107,2834,2205,106,213,1580,1363,2784,622,2046,75,1143,24,2558,186,399,2628,698,469,2435,2797,94,2143,2752,2376,1149,3230,420
|
-0.5530485515520936,-0.33047177855621607,4.49169826573745,-0.9346541779980903,0.36404879012622693,-0.06375283048767906,0.290698308478738,-0.3032458564235702,3.2021083972634283,1.477268471012952,-0.037732006077157064,-0.7259155280154393,-0.19559772347892793,-0.8144047886641401,-0.11613860568977677,1.0978302599790803,3.5826739461700328,0.013971984461395193,-0.2761470099076228,-0.16899212443771205,-0.5814925595785796,-0.44067800799054646,-0.3578263417200354,5.238210069294953,-0.38531114273962846,-0.08988792448924106,-0.3032458564235702,3.185852181395418,-0.6967305875166148,5.096383797522485,-0.44067800799054646,0.36404879012622693,-0.11613860568977677,4.991829849894577,-0.2761470099076228,3.8867761966938223,1.3531319100008414,-0.08988792448924106,-0.16899212443771205,0.290698308478738,-0.3032458564235702,3.426283702043037,-0.6388152651515875,0.80972375426467,-0.6100808230827668,0.11606410191198446,-0.11613860568977677,-0.22232443406475605,-1.8242310197178253,0.16647131175699767,-0.16899212443771205,-0.08988792448924106,0.11606410191198446,4.165756851456292,-0.037732006077157064,0.460522082895191,5.796784418092093,-0.011824157758994824,-0.41292781072703233,-5.435792321266738,0.14131998091565823,-1.411267133335394,0.16647131175699767,-0.08988792448924106,-0.2761470099076228,-0.2491737041569007,0.06523411656369492,0.013971984461395193,-0.8741983970490654,-0.2491737041569007,0.21646479318514736,-0.22232443406475605,-0.11613860568977677,2.0100448717400776,-0.5247469164830378,-0.14250621643165773,-0.6100808230827668,0.3152452291356413,-0.037732006077157064,-0.38531114273962846,0.09070253409564899,-0.49658581124515616,-0.6388152651515875,0.6954312126789955,0.764249500072063,-0.16899212443771205,-0.6388152651515875,-0.5247469164830378,-0.3578263417200354,-0.38531114273962846,-0.6676978506562085,-0.14250621643165773,0.11606410191198446,-0.44067800799054646,-0.5530485515520936,0.3883074039088583,0.06523411656369492,-0.3032458564235702,-0.41292781072703233,-0.2761470099076228,0.26605328440668863,-0.19559772347892793,0.26605328440668863,0.6025084155120215,-0.011824157758994824,-1.2799168876410205,4.7385298944612435,-0.38531114273962846,-0.5247469164830378,-0.41292781072703233,-0.7259155280154393,-0.16899212443771205,1.247929148925315,-0.08988792448924106,-0.011824157758994824,0.5319144280730378,-0.2491737041569007,-0.11613860568977677,0.6025084155120215,0.290698308478738,2.104478107048702,-0.5247469164830378,-0.2491737041569007,2.1232180943348267,0.9885086777190719,-0.037732006077157064,0.03965766766041974,-0.49658581124515616,0.36404879012622693,-0.19559772347892793,3.0047879739765255,0.11606410191198446,4.752042300962526,-0.38531114273962846,1.1194802025914279,0.5790643592485345,-0.41292781072703233,0.3152452291356413,0.5082068465574456,-0.33047177855621607,-0.49658581124515616,2.416723651268817,-0.22232443406475605,-0.46856343097646624,-0.3032458564235702,0.11606410191198446,-0.8144047886641401,0.5555333123030265
| 3,447
|
Glial cell differentiation
| 9
| 43
| 2.680879
| 0.007343
|
P05067,Q00534,P01130,P19022,Q92542,P21359,P04062,P10909,Q07954
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
66,290,73,110,50,220,114,58,60
|
803,757,2386,73,114,66,1032,488,1537,2083,58,405,110,220,1249,2466,1035,1937,1255,1177,1468,1261,1944,290,2103,2346,2670,60,1637,2348,3089,1479,3129,2284,831,50,2687,743,2045,351,1830,2323,798
|
0.24130912809996094,0.26605328440668863,-0.33047177855621607,3.0214219227005468,1.952786157251336,3.185852181395418,0.14131998091565823,0.460522082895191,-0.037732006077157064,-0.22232443406475605,3.4892019402118737,0.5555333123030265,2.0100448717400776,0.944268201707387,0.06523411656369492,-0.3578263417200354,0.14131998091565823,-0.16899212443771205,0.06523411656369492,0.09070253409564899,-0.011824157758994824,0.06523411656369492,-0.16899212443771205,0.7413917409113739,-0.22232443406475605,-0.3032458564235702,-0.44067800799054646,3.362871077444676,-0.06375283048767906,-0.3032458564235702,-0.6967305875166148,-0.011824157758994824,-0.7259155280154393,-0.2761470099076228,0.24130912809996094,3.736124836573613,-0.44067800799054646,0.290698308478738,-0.19559772347892793,0.6491388771216718,-0.11613860568977677,-0.2761470099076228,0.26605328440668863
| 3,447
|
Lipid transporter activity
| 7
| 21
| 2.680638
| 0.007348
|
Q7Z3C6,P17900,Q9NV96,P08183,P33527,P61916,O15118
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
132,4,271,113,153,28,57
|
2002,57,113,263,4,1171,1398,3381,153,1469,28,869,576,994,2417,132,1011,1979,3140,887,271
|
-0.19559772347892793,3.520478778498601,1.9910092185928823,0.80972375426467,5.796784418092093,0.09070253409564899,0.013971984461395193,-1.3451913690083444,1.4154814144632912,-0.011824157758994824,4.602257829733616,0.21646479318514736,0.3883074039088583,0.16647131175699767,-0.33047177855621607,1.6593829626856886,0.16647131175699767,-0.16899212443771205,-0.7259155280154393,0.21646479318514736,0.80972375426467
| 3,447
|
Dysostosis multiplex
| 6
| 8
| 2.677249
| 0.007423
|
P15586,P16278,P04066,P10619,P54802,O00754
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
1,35,11,47,25,30
|
30,11,47,1,35,25,744,75
|
4.49169826573745,5.238210069294953,3.8568635354262555,6.058298299026471,4.165756851456292,4.7385298944612435,0.290698308478738,3.0047879739765255
| 3,447
|
Ensheathment of neurons
| 8
| 28
| 2.674951
| 0.007474
|
Q12959,P07686,Q92542,P53634,Q15058,P10909,P21359,Q7L576
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
408,46,50,20,379,58,220,223
|
1691,968,1770,46,58,405,220,1035,1937,1468,1261,20,408,1637,2348,1478,379,2284,875,223,50,2045,1971,3329,1830,798,2072,3176
|
-0.08988792448924106,0.16647131175699767,-0.11613860568977677,3.8867761966938223,3.4892019402118737,0.5555333123030265,0.944268201707387,0.14131998091565823,-0.16899212443771205,-0.011824157758994824,0.06523411656369492,4.872739253374519,0.5555333123030265,-0.06375283048767906,-0.3032458564235702,-0.011824157758994824,0.6025084155120215,-0.2761470099076228,0.21646479318514736,0.944268201707387,3.736124836573613,-0.19559772347892793,-0.16899212443771205,-1.0266222601373636,-0.11613860568977677,0.26605328440668863,-0.19559772347892793,-0.7552547701634187
| 3,447
|
Immunoglobulin subtype [IPR003599]
| 6
| 12
| 2.673897
| 0.007498
|
P35613,P78310,Q92859,Q9Y624,Q13740,P43121
|
Sequence
|
InterPro Domain
|
interpro_domain
|
160,136,23,121,154,126
|
2257,2085,160,126,136,725,154,2130,23,175,1520,121
|
-0.2761470099076228,-0.22232443406475605,1.3739783978655824,1.7388215146356225,1.6193233192302938,0.290698308478738,1.4154814144632912,-0.22232443406475605,4.792456598943272,1.1840120855874656,-0.011824157758994824,1.8368772029414835
| 3,447
|
Immunoglobulin subtype 2 [IPR003598]
| 6
| 12
| 2.673897
| 0.007498
|
P35613,P78310,Q92859,Q9Y624,Q13740,P43121
|
Sequence
|
InterPro Domain
|
interpro_domain
|
160,136,23,121,154,126
|
2257,2085,160,126,136,725,154,2130,23,175,1520,121
|
-0.2761470099076228,-0.22232443406475605,1.3739783978655824,1.7388215146356225,1.6193233192302938,0.290698308478738,1.4154814144632912,-0.22232443406475605,4.792456598943272,1.1840120855874656,-0.011824157758994824,1.8368772029414835
| 3,447
|
Other glycan degradation
| 7
| 8
| 2.669956
| 0.007586
|
P16278,P04066,Q99519,P07686,P06865,Q9BTY2,O00754
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
35,11,75,46,14,24,30
|
30,114,11,14,46,35,75,24
|
4.49169826573745,1.952786157251336,5.238210069294953,4.991829849894577,3.8867761966938223,4.165756851456292,3.0047879739765255,4.752042300962526
| 3,447
|
Cargo receptor activity
| 7
| 9
| 2.667797
| 0.007635
|
Q5KU26,P01130,Q08380,P02786,Q14108,Q07954,Q8WTV0
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
38,73,16,52,26,60,62
|
98,73,52,60,16,26,3343,38,62
|
2.326250857937109,3.0214219227005468,3.6443989474477476,3.362871077444676,4.95230803704758,4.7385298944612435,-1.0888207132458592,4.136820106166587,3.3469394788706537
| 3,447
|
Subsets and Splits
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