term stringlengths 2 121 | overlap int64 6 281 | setsize int64 7 499 | score float64 1.96 10.6 | pval float64 0 0.05 | edge stringlengths 41 1.97k | type stringclasses 5
values | subtype stringclasses 24
values | subtype_key stringclasses 24
values | edge_idxs stringlengths 11 1.17k | ann_idxs stringlengths 19 2.31k | ann_vals stringlengths 124 9.94k | sig_size int64 2.2k 3.73k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Eukaryotic translation elongation | 47 | 77 | 3.293241 | 0.00099 | P62266,P83881,P62753,P62917,P46782,P42766,P62701,P63173,P60866,P39023,P35268,P08708,P62857,P27635,Q9Y3U8,P62750,P62277,P62847,P62269,P46778,P61927,P61254,P13639,P18621,P47914,P63220,P62899,P46779,P26641,P61513,P62841,P18077,P61247,P83731,P62244,Q02543,Q02878,P62854,P25398,P62241,P46776,P49207,P36578,P62910,P15880,P6131... | Processes and pathways | Reactome Pathways | msigdb_reactome | 621,1011,622,1266,869,503,1265,508,1262,1001,1258,1399,271,771,566,1419,1417,662,1416,288,541,1200,1182,1184,824,452,451,1193,1322,696,937,820,1066,578,1067,830,831,344,337,1340,473,1333,1329,241,992,240,121 | 3179,2476,1399,2412,1182,992,820,2480,1184,1613,2094,337,1881,1322,771,1966,1814,2097,1258,1329,2611,1001,1475,503,473,2102,288,1193,1737,869,2175,824,1333,1822,1262,1066,1200,240,1896,696,541,1898,1340,1067,2111,1415,621,1416,1417,2487,2044,1265,1419,622,1482,937,662,1741,344,271,1624,1625,451,2112,241,2045,1266,508,4... | -0.9628854457235239,-0.4080005745537821,0.22000783347747066,-0.36855296551083955,0.3370401206025548,0.4538605613386647,0.5704749577465287,-0.4080005745537821,0.3370401206025548,0.10275757306645614,-0.17171116116859408,1.1121055878194461,-0.05392643070728478,0.25904250556837555,0.6093015947704223,-0.09316168383661999,-0... | 3,643 |
Cysteine type endopeptidase activity | 18 | 31 | 3.28469 | 0.001021 | O94782,Q8NB14,Q9Y4E8,P42574,Q96RU2,Q96K76,Q14674,P17655,P55212,P45974,Q9GZR1,O15484,P40818,Q86UV5,Q9Y4P1,Q14694,P51784,Q9UDY8 | Functions | GO Molecular function | msigdb_gomf | 128,320,99,223,133,636,294,8,661,504,77,568,446,275,127,365,238,563 | 568,3432,128,2597,2223,8,2609,446,223,504,238,1198,872,661,698,294,365,275,320,3447,2563,1292,1573,636,133,77,1101,563,1166,99,127 | 0.8031073486334814,-1.3220153104882866,1.688119532883408,-0.48697317960573294,-0.2503677045331832,4.1799723104062085,-0.48697317960573294,0.9577701211888938,1.3430177439240172,0.8804803264068664,1.3045804843879147,0.3370401206025548,0.5316260405382865,0.7256497757208881,0.6868888119615674,1.1891538675508655,1.073551824... | 3,643 |
Toll like receptor cascades | 26 | 36 | 3.282927 | 0.001027 | Q04206,P28482,Q16539,Q13546,P51812,P49137,Q14738,Q06124,P46734,P51617,Q15418,O43318,O14733,P27361,O15111,P51452,Q13616,P09429,P61088,Q16644,Q15075,Q8IV63,O14920,Q6SZW1,Q02750,O60443 | Processes and pathways | Reactome Pathways | msigdb_reactome | 623,1121,394,257,13,1002,296,293,538,290,61,686,183,1057,66,930,1072,818,827,1020,1019,741,221,738,1012,983 | 183,221,66,686,983,2924,818,3335,1057,1121,1408,1122,538,1002,1683,930,290,13,827,1826,1012,623,293,257,1072,296,1019,61,2894,394,1020,738,741,1772,2755,1784 | 1.4582167193470499,1.3430177439240172,2.146041665971875,0.6868888119615674,0.4538605613386647,-0.724494224850264,0.5704749577465287,-1.1621798444446965,0.4149435883630969,0.3760035130473384,0.22000783347747066,0.3760035130473384,0.8418043225749562,0.4538605613386647,0.06362460524619651,0.49275464296587623,1.18915386755... | 3,643 |
Dna repair pathways full network | 24 | 59 | 3.274937 | 0.001057 | O94782,P27695,Q9NR33,P49916,Q9NVI1,P35244,P40938,Q13535,P29372,Q9BX63,P43246,Q9UQ84,Q14191,O14757,P20585,Q92889,P09429,P52701,P18858,P28340,P38398,Q9Y620,P18074,Q8TAF3 | Processes and pathways | WikiPathways | msigdb_wp | 128,615,404,7,806,144,773,779,414,182,417,56,457,65,575,75,818,694,821,823,339,100,725,518 | 65,2346,128,818,1468,1732,2777,1320,1807,1402,725,821,2226,923,575,2227,615,823,414,1257,144,2356,2536,1546,339,1736,2035,773,868,417,1971,7,3027,1197,694,1549,3144,2177,1627,1270,1071,779,2184,457,1982,1428,518,3004,75,2710,182,1094,404,1779,806,1948,56,1591,100 | 2.184093386153049,-0.3291314594756453,1.688119532883408,0.5704749577465287,0.18094894503092676,0.024466452206715977,-0.605622205270541,0.25904250556837555,-0.014717140094497816,0.22000783347747066,0.6481061483680024,0.5704749577465287,-0.2503677045331832,0.49275464296587623,0.8031073486334814,-0.2503677045331832,0.7643... | 3,643 |
Chromosome separation | 19 | 43 | 3.265241 | 0.001094 | Q96EA4,Q9BVS4,Q9H4L7,Q14674,Q9UJX3,O43683,Q9Y6A5,Q92889,O43264,Q15003,Q13257,P33981,Q13618,Q99741,O43670,Q15398,Q9Y6G9,O60566,P14635 | Processes and pathways | GO Biological process | msigdb_gobp | 401,278,559,294,64,67,602,75,441,212,580,208,582,228,470,370,647,356,108 | 441,2588,470,67,1729,2828,356,612,3416,2092,108,1249,1408,2032,208,2677,1684,3259,1487,3189,580,582,294,2054,212,370,1209,1211,75,794,401,2754,228,278,1934,559,1155,2390,64,1786,2655,602,647 | 0.9577701211888938,-0.48697317960573294,0.9191355351926671,2.146041665971875,0.024466452206715977,-0.6452217131559657,1.073551824278558,0.7643892266436848,-1.2820237758068287,-0.17171116116859408,1.764610992500279,0.2980531923406561,0.22000783347747066,-0.132423168996273,1.3814361078072093,-0.5264977250215082,0.0636246... | 3,643 |
Dna double strand break repair | 13 | 65 | 3.236947 | 0.001208 | O14757,Q5UIP0,Q9NR33,Q92547,P49916,Q92889,Q9BX63,Q9UNS1,P35244,Q9UQ84,P38398,Q8N2W9,P51530 | Processes and pathways | Reactome Pathways | msigdb_reactome | 65,2,404,37,7,75,182,280,144,56,339,191,152 | 605,65,2588,3057,1394,2346,2409,1538,3250,1468,1732,2777,1320,1402,2226,1812,2227,823,144,2356,2536,1546,339,1736,2035,773,1971,7,3027,152,2787,932,1620,2177,1552,827,1414,3106,1627,875,1270,2308,1071,779,457,2489,2,191,37,3004,75,2327,556,182,902,404,1779,2461,3052,855,1948,2273,280,56,1591 | 0.7643892266436848,2.184093386153049,-0.48697317960573294,-0.8435837193418066,0.22000783347747066,-0.3291314594756453,-0.36855296551083955,0.14186560484493307,-1.0425353636919736,0.18094894503092676,0.024466452206715977,-0.605622205270541,0.25904250556837555,0.22000783347747066,-0.2503677045331832,-0.014717140094497816... | 3,643 |
Regulation of chromosome segregation | 22 | 46 | 3.236712 | 0.001209 | Q96EA4,Q99661,Q14671,Q9BVS4,Q14674,Q9UJX3,O43683,Q9Y6A5,Q7Z5K2,O43264,Q69YH5,Q13257,P33981,Q9P258,Q13618,Q99741,O43670,Q15398,Q9Y6G9,O60566,P14635,P06400 | Processes and pathways | GO Biological process | msigdb_gobp | 401,675,146,278,294,64,67,602,201,441,346,580,208,754,582,228,470,370,647,356,108,612 | 441,2588,470,67,1729,2828,356,612,2092,108,1249,2032,208,1970,2677,1684,3341,1487,3189,580,582,146,294,2054,370,1209,1211,346,201,3318,794,401,2754,2263,675,228,278,1934,1155,754,2390,64,1786,2655,602,647 | 0.9577701211888938,-0.48697317960573294,0.9191355351926671,2.146041665971875,0.024466452206715977,-0.6452217131559657,1.073551824278558,0.7643892266436848,-0.17171116116859408,1.764610992500279,0.2980531923406561,-0.132423168996273,1.3814361078072093,-0.09316168383661999,-0.5264977250215082,0.06362460524619651,-1.16217... | 3,643 |
Selenoamino acid metabolism | 56 | 90 | 3.225103 | 0.001259 | P62266,P83881,P47897,P62753,P23526,P62917,P46782,P42766,P62701,P63173,P60866,P39023,P35268,P14868,P08708,P62857,P27635,O95340,Q9Y3U8,Q96I15,P54136,P62750,P62277,P62847,P62269,O43252,P61927,P46778,P61254,P18621,P47914,P63220,P62899,P46779,Q16881,P61513,P62841,P18077,P61247,P83731,P62244,Q02543,Q02878,P62854,P25398,P6224... | Processes and pathways | Reactome Pathways | msigdb_reactome | 621,1011,505,622,996,1266,869,503,1265,508,1262,1001,1258,1401,1399,271,771,151,566,1222,775,1419,1417,662,1416,532,541,288,1200,1184,824,452,451,1193,314,696,937,820,1066,578,1067,830,831,344,337,1340,473,1333,1329,1014,990,241,359,992,240,121 | 532,2520,151,359,3179,2476,990,1399,2412,1401,992,820,2480,1184,1613,996,337,1881,771,1814,2097,1258,1329,2611,1001,1475,1616,503,473,2102,288,1193,1737,869,2175,505,824,1333,1738,1822,775,2418,1262,1066,1200,240,1896,696,541,1898,1340,1067,2111,1415,621,1416,1417,2487,2044,1265,1419,622,1482,937,662,1741,344,271,1624,... | 0.8418043225749562,-0.44747405503507703,1.5732494325114137,1.073551824278558,-0.9628854457235239,-0.4080005745537821,0.4538605613386647,0.22000783347747066,-0.36855296551083955,0.22000783347747066,0.4538605613386647,0.5704749577465287,-0.4080005745537821,0.3370401206025548,0.10275757306645614,0.4538605613386647,1.11210... | 3,643 |
Cullin ring ubiquitin ligase complex | 18 | 39 | 3.222502 | 0.001271 | Q8TEB1,Q96ME1,Q14145,Q96K76,Q14999,Q86VP6,Q66K64,Q12834,Q93034,O60566,Q13309,Q15369,Q9Y3I1,Q9Y4B6,Q16763,Q13618,Q9NZJ0,Q9UJX3 | Localization | GO Cellular component | msigdb_gocc | 399,264,6,636,884,739,246,509,845,356,733,886,860,716,58,582,60,64 | 356,3280,2032,3069,1826,509,1487,733,1072,1693,582,2184,6,884,886,2431,1982,58,2437,246,739,399,1846,845,961,636,264,1934,1655,2338,2078,60,1040,2390,64,1786,2655,860,716 | 1.073551824278558,-1.0823944165347616,-0.132423168996273,-0.8435837193418066,-0.014717140094497816,0.8804803264068664,0.18094894503092676,0.6481061483680024,0.4149435883630969,0.06362460524619651,0.8031073486334814,-0.21102594097074423,4.775434762616395,0.5316260405382865,0.5316260405382865,-0.36855296551083955,-0.0931... | 3,643 |
Neoplasm of the large intestine | 20 | 49 | 3.192695 | 0.00141 | Q14145,P42766,Q8WX93,P62857,Q9UPY3,P62847,P43246,Q13485,O43683,P62899,Q8NFG4,P20585,P54277,P62854,P38398,Q9Y620,O14965,P63167,O60566,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 6,503,674,271,565,662,417,188,67,451,202,575,87,344,339,100,468,363,356,240 | 468,67,1729,356,2923,3250,1399,1671,3367,820,575,2352,823,3025,3140,339,2611,503,417,2102,2175,694,1620,87,1262,1200,240,1896,1898,1067,662,344,271,451,2045,363,2048,1270,1423,188,6,2188,1209,1428,2366,202,674,565,100 | 0.9191355351926671,2.146041665971875,0.024466452206715977,1.073551824278558,-0.724494224850264,-1.0425353636919736,0.22000783347747066,0.06362460524619651,-1.2021058814321368,0.5704749577465287,0.8031073486334814,-0.3291314594756453,0.5704749577465287,-0.8038633863877657,-0.9230949351912728,1.1121055878194461,-0.486973... | 3,643 |
Cell cycle | 20 | 60 | 3.187057 | 0.001437 | P30307,Q14566,Q12834,P11802,Q14674,O95067,Q9UBD5,Q9UJX3,O14757,Q13485,O43683,Q13257,P33981,Q99741,P49841,O60566,P14635,Q00534,P25205,P06400 | Processes and pathways | KEGG Pathways | msigdb_kegg | 136,145,509,142,294,172,330,64,65,188,67,580,208,228,475,356,108,242,361,612 | 65,67,1729,1237,2975,2828,356,1602,172,3250,612,1120,142,1732,108,1812,361,1544,1324,2032,136,1256,208,2034,2355,2833,1410,475,1684,1339,620,1685,1826,1627,242,2619,509,1487,580,733,2851,188,779,1205,1072,145,294,2490,3080,3226,2564,228,1934,330,2390,64,1786,2655,2823,2519 | 2.184093386153049,2.146041665971875,0.024466452206715977,0.2980531923406561,-0.7641668235232126,-0.6452217131559657,1.073551824278558,0.10275757306645614,1.496579247199708,-1.0425353636919736,0.7643892266436848,0.3760035130473384,1.611557358304762,0.024466452206715977,1.764610992500279,-0.014717140094497816,1.073551824... | 3,643 |
Brainderived neurotrophic factor bdnf signaling pathway | 20 | 47 | 3.149023 | 0.001638 | Q04206,P62753,Q16539,P51812,Q14012,Q06124,P49815,P19174,P42224,Q00535,Q15418,P40763,O15111,Q13501,Q96S59,P67809,P42574,O14920,P49841,P54646 | Processes and pathways | WikiPathways | msigdb_wp | 623,622,394,13,510,293,419,52,416,176,61,692,66,70,215,209,223,221,475,477 | 2398,221,66,1877,688,3367,1182,2294,3369,52,1250,997,1057,1121,1325,3140,692,416,1969,223,2839,419,475,13,477,2681,622,2891,1483,1010,209,1743,3147,176,1012,623,293,70,510,61,394,1754,1287,2133,215,2210,2147 | -0.36855296551083955,1.3430177439240172,2.146041665971875,-0.05392643070728478,0.6868888119615674,-1.2021058814321368,0.3370401206025548,-0.2897362923580755,-1.2021058814321368,2.3361396571918536,0.2980531923406561,0.4538605613386647,0.4149435883630969,0.3760035130473384,0.25904250556837555,-0.9230949351912728,0.686888... | 3,643 |
Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters | 11 | 18 | 3.131921 | 0.001737 | P27695,Q9UPY3,O75818,Q96DE0,Q96F86,Q9BRJ7,Q9BQ52,Q9BQG2,Q9UQ84,Q9UK59,P51530 | Functions | GO Molecular function | msigdb_gomf | 615,565,334,38,178,181,710,350,56,232,152 | 1234,2161,334,615,1736,152,1341,1428,38,178,744,710,350,181,2713,232,565,56 | 0.2980531923406561,-0.21102594097074423,1.1121055878194461,0.7643892266436848,0.024466452206715977,1.5732494325114137,0.25904250556837555,0.22000783347747066,2.5637384998763477,1.496579247199708,0.6481061483680024,0.6868888119615674,1.1121055878194461,1.496579247199708,-0.5264977250215082,1.3430177439240172,0.841804322... | 3,643 |
Homology directed repair | 12 | 52 | 3.131218 | 0.001741 | O14757,Q9NR33,Q92547,P49916,Q92889,Q9BX63,Q9UNS1,P35244,Q9UQ84,P38398,Q8N2W9,P51530 | Processes and pathways | Reactome Pathways | msigdb_reactome | 65,404,37,7,75,182,280,144,56,339,191,152 | 65,2588,1394,2346,2409,1538,1468,1732,1402,2226,1812,2227,823,144,2356,2536,1546,339,1736,2035,773,1971,7,3027,152,1620,2177,1552,827,1414,3106,1270,2308,779,457,2489,191,37,3004,75,556,182,902,404,1779,2461,3052,855,1948,280,56,1591 | 2.184093386153049,-0.48697317960573294,0.22000783347747066,-0.3291314594756453,-0.36855296551083955,0.14186560484493307,0.18094894503092676,0.024466452206715977,0.22000783347747066,-0.2503677045331832,-0.014717140094497816,-0.2503677045331832,0.5704749577465287,1.611557358304762,-0.3291314594756453,-0.44747405503507703... | 3,643 |
Nucleoside monophosphate biosynthetic process | 14 | 28 | 3.12085 | 0.001803 | P55263,P34896,P27707,P04183,P27708,P00492,P00813,P49915,Q01433,O76075,Q9BZX2,P04818,P33316,O15067 | Processes and pathways | GO Biological process | msigdb_gobp | 618,691,822,163,472,385,411,476,389,49,351,235,362,184 | 184,49,385,411,163,235,1669,1672,1319,995,1252,1964,822,472,1679,867,1123,1614,2413,362,691,476,618,1553,389,1745,1130,351 | 1.4582167193470499,2.3741115925465395,1.034978100199594,0.9963842539114091,1.5349234398797262,1.3045804843879147,0.06362460524619651,0.06362460524619651,0.25904250556837555,0.4538605613386647,0.2980531923406561,-0.09316168383661999,0.5704749577465287,0.9191355351926671,0.06362460524619651,0.5316260405382865,0.376003513... | 3,643 |
Interleukin 17 signaling | 19 | 23 | 3.065508 | 0.002173 | P28482,Q16539,P51812,P49137,Q14738,P46734,P51617,Q15418,O43318,O14733,P27361,O15111,P51452,Q13616,P61088,Q16644,Q8IV63,O14920,Q02750 | Processes and pathways | Reactome Pathways | msigdb_reactome | 1121,394,13,1002,296,538,290,61,686,183,1057,66,930,1072,827,1020,741,221,1012 | 183,221,66,686,1057,1121,1408,1122,538,1002,930,290,13,827,1826,1012,1072,296,61,2894,394,1020,741 | 1.4582167193470499,1.3430177439240172,2.146041665971875,0.6868888119615674,0.4149435883630969,0.3760035130473384,0.22000783347747066,0.3760035130473384,0.8418043225749562,0.4538605613386647,0.49275464296587623,1.1891538675508655,3.618950764638868,0.5704749577465287,-0.014717140094497816,0.4538605613386647,0.41494358836... | 3,643 |
Regulation of tp53 activity through phosphorylation | 14 | 40 | 3.060387 | 0.002211 | O14757,Q13526,Q92547,O14965,Q16539,Q8IW41,Q9BX63,P54646,P35244,Q00535,Q9UQ84,Q14191,P38398,P51530 | Processes and pathways | Reactome Pathways | msigdb_reactome | 65,130,37,468,394,10,182,477,144,176,56,457,339,152 | 65,468,1394,2346,3250,1402,1249,1812,2227,144,2356,2536,339,2035,773,2932,3027,152,1620,2842,477,1899,176,776,130,779,457,394,1138,10,37,3227,3004,2754,556,182,1383,56,3300,2014 | 2.184093386153049,0.9191355351926671,0.22000783347747066,-0.3291314594756453,-1.0425353636919736,0.22000783347747066,0.2980531923406561,-0.014717140094497816,-0.2503677045331832,1.611557358304762,-0.3291314594756453,-0.44747405503507703,1.1121055878194461,-0.132423168996273,0.6093015947704223,-0.724494224850264,-0.8038... | 3,643 |
Apc c mediated degradation of cell cycle proteins | 31 | 61 | 3.046627 | 0.002314 | P06400,P61289,P06493,Q92530,P20618,P28070,Q06323,Q12834,Q9UL46,Q96DE5,O00233,P25789,P62191,Q16763,Q9UJX3,P25788,Q13200,Q13616,Q13257,Q15008,O75832,P51665,O14965,P60900,O60566,Q13309,O00487,P14635,O14818,O43242,P25786 | Processes and pathways | Reactome Pathways | msigdb_reactome | 612,129,1120,791,994,255,256,509,811,961,381,770,1201,58,64,1188,943,1072,580,1017,335,728,468,731,356,733,606,108,1112,862,865 | 1597,2219,381,606,1112,468,862,1729,356,335,612,1120,108,2027,994,1812,865,1407,1188,770,1323,255,2228,1473,2032,2298,2415,2235,1335,2358,728,1684,1261,731,129,1201,2110,1481,1826,256,509,1487,943,580,733,1072,1273,1017,58,791,961,2754,1577,2068,1934,2390,64,1786,2655,811,1861 | 0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,0.9191355351926671,0.5316260405382865,0.024466452206715977,1.073551824278558,1.1121055878194461,0.7643892266436848,0.3760035130473384,1.764610992500279,-0.132423168996273,0.4538605613386647,-0.014717140094497816,0.5316260405... | 3,643 |
Toll like receptor 9 tlr9 cascade | 22 | 29 | 3.029963 | 0.002446 | Q04206,P28482,Q16539,P51812,P49137,Q14738,P46734,P51617,Q15418,O43318,O14733,P27361,O15111,P51452,Q13616,P09429,P61088,Q16644,Q15075,Q8IV63,O14920,Q02750 | Processes and pathways | Reactome Pathways | msigdb_reactome | 623,1121,394,13,1002,296,538,290,61,686,183,1057,66,930,1072,818,827,1020,1019,741,221,1012 | 183,221,66,686,2924,818,1057,1121,1408,1122,538,1002,930,290,13,827,1826,1012,623,1072,296,1019,61,2894,394,1020,741,1772,2755 | 1.4582167193470499,1.3430177439240172,2.146041665971875,0.6868888119615674,-0.724494224850264,0.5704749577465287,0.4149435883630969,0.3760035130473384,0.22000783347747066,0.3760035130473384,0.8418043225749562,0.4538605613386647,0.49275464296587623,1.1891538675508655,3.618950764638868,0.5704749577465287,-0.0147171400944... | 3,643 |
Endoribonuclease activity producing 5 phosphomonoesters | 10 | 16 | 3.028553 | 0.002457 | P27695,Q9UPY3,O75818,Q96DE0,Q96F86,Q9BRJ7,Q9BQ52,Q9BQG2,Q9UQ84,Q9UK59 | Functions | GO Molecular function | msigdb_gomf | 615,565,334,38,178,181,710,350,56,232 | 1234,2161,334,615,1736,1341,38,178,744,710,350,181,2713,232,565,56 | 0.2980531923406561,-0.21102594097074423,1.1121055878194461,0.7643892266436848,0.024466452206715977,0.25904250556837555,2.5637384998763477,1.496579247199708,0.6481061483680024,0.6868888119615674,1.1121055878194461,1.496579247199708,-0.5264977250215082,1.3430177439240172,0.8418043225749562,2.3361396571918536 | 3,643 |
Centriolar satellite | 21 | 41 | 3.023687 | 0.002497 | P41208,O15344,Q14145,Q5SVZ6,O43169,O43379,Q9Y5K6,Q8N3F8,Q96QE3,Q53EZ4,Q9UPN4,Q9Y6A5,Q86UY6,Q7Z4H7,Q8NI35,Q9Y4W2,Q86YS7,O75449,Q15398,Q12873,Q15154 | Localization | Protein Atlas Subcellular | protein_atlas_subcellular_location_all | 868,498,6,33,42,283,978,192,591,189,858,602,586,79,347,86,894,722,370,732,122 | 1232,498,42,283,1462,1050,1872,722,1117,1673,1816,868,1342,1555,941,732,1488,6,2854,122,370,1564,189,33,79,586,2698,894,192,347,3157,2376,591,3169,858,2579,2277,3470,86,978,602 | 0.2980531923406561,0.8804803264068664,2.450008614360997,1.1891538675508655,0.18094894503092676,0.4149435883630969,-0.05392643070728478,0.6481061483680024,0.3760035130473384,0.06362460524619651,-0.014717140094497816,0.5316260405382865,0.25904250556837555,0.14186560484493307,0.49275464296587623,0.6481061483680024,0.18094... | 3,643 |
Neoplasm of the colon | 17 | 39 | 3.020033 | 0.002527 | Q13485,O43683,P62899,Q8NFG4,P42766,P62847,P20585,Q8WX93,P52701,P18077,P43246,O60566,P54277,P62857,P62854,P38398,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 188,67,451,202,503,662,575,674,694,820,417,356,87,271,344,339,240 | 67,1729,356,3250,1399,1671,820,575,2352,823,3025,339,2611,503,417,2102,2175,694,1620,87,1262,1200,240,1896,1898,1067,662,344,271,451,2045,2048,1270,188,1209,1428,2366,202,674 | 2.146041665971875,0.024466452206715977,1.073551824278558,-1.0425353636919736,0.22000783347747066,0.06362460524619651,0.5704749577465287,0.8031073486334814,-0.3291314594756453,0.5704749577465287,-0.8038633863877657,1.1121055878194461,-0.48697317960573294,0.8804803264068664,0.9963842539114091,-0.17171116116859408,-0.2110... | 3,643 |
Ubiquitin ligase complex | 36 | 79 | 3.017491 | 0.002549 | Q8TEB1,Q96ME1,Q14145,Q9UBS8,Q14999,Q12834,O75150,Q99728,Q9UL63,Q9Y2Z0,Q93034,Q6NTF9,Q9Y3I1,Q12933,Q9Y4B6,Q16763,Q9NZJ0,Q9UJX3,Q9NT62,Q96S59,P61088,Q14139,Q13618,P38398,Q96K76,Q86VP6,Q8IVV7,Q9H7D7,Q66K64,Q9BTE7,O60566,Q13309,Q9Y4X5,Q15369,Q7Z569,O95155 | Localization | GO Cellular component | msigdb_gocc | 399,264,6,529,884,509,22,556,41,45,845,839,860,455,716,58,60,64,218,215,827,211,582,339,636,739,372,901,246,113,356,733,911,886,123,864 | 356,22,3280,987,864,1666,2032,339,827,3069,1826,938,509,455,1487,733,1072,1693,582,2184,211,6,2621,884,886,2431,1982,58,2437,2995,246,839,1758,2194,123,739,2370,372,2252,399,3447,1846,845,1087,3639,961,636,264,2133,215,2327,556,113,2644,1934,901,1655,2714,218,2338,3011,3052,2078,60,529,2212,3170,1040,2390,64,1786,2655,... | 1.073551824278558,3.0927128631856373,-1.0823944165347616,0.4538605613386647,0.5316260405382865,0.06362460524619651,-0.132423168996273,1.1121055878194461,0.5704749577465287,-0.8435837193418066,-0.014717140094497816,0.49275464296587623,0.8804803264068664,0.9577701211888938,0.18094894503092676,0.6481061483680024,0.4149435... | 3,643 |
Retinoblastoma gene in cancer | 23 | 54 | 3.01619 | 0.00256 | Q14527,Q14566,P35244,P11802,P40938,O95347,Q99728,Q9NQW6,P26358,O95067,O14757,Q16204,P26583,P27707,P52701,P33981,P23921,Q13309,P14635,Q00534,P25205,P04818,P06400 | Processes and pathways | WikiPathways | msigdb_wp | 258,145,144,142,773,383,556,434,536,172,65,313,309,822,694,208,222,733,108,242,361,235,612 | 65,1602,172,989,383,1466,3250,235,612,1120,818,1400,3416,142,1732,108,1402,2295,222,1812,361,536,309,2227,822,1124,208,2034,2833,144,2356,2035,773,1334,694,2177,1627,242,1270,1690,733,2851,1205,258,145,2490,313,1348,2325,556,434,2213,2823,2519 | 2.184093386153049,0.10275757306645614,1.496579247199708,0.4538605613386647,1.034978100199594,0.18094894503092676,-1.0425353636919736,1.3045804843879147,0.7643892266436848,0.3760035130473384,0.5704749577465287,0.22000783347747066,-1.2820237758068287,1.611557358304762,0.024466452206715977,1.764610992500279,0.220007833477... | 3,643 |
Base excision repair | 10 | 22 | 2.998287 | 0.002715 | P27695,Q7Z6Z7,Q96K76,P49916,P29372,P18858,P35244,Q86W56,Q14191,P51530 | Processes and pathways | GO Biological process | msigdb_gobp | 615,630,636,7,414,821,144,587,457,152 | 1732,1807,1402,821,2226,1613,2227,615,823,414,144,1736,7,152,1270,457,630,587,636,2710,2077,1948 | 0.024466452206715977,-0.014717140094497816,0.22000783347747066,0.5704749577465287,-0.2503677045331832,0.10275757306645614,-0.2503677045331832,0.7643892266436848,0.5704749577465287,0.9963842539114091,1.611557358304762,0.024466452206715977,4.291847410390771,1.5732494325114137,0.2980531923406561,0.9577701211888938,0.76438... | 3,643 |
Dna damage response | 10 | 26 | 2.995169 | 0.002743 | O14757,P42574,P30307,Q86UE8,Q7LG56,Q00535,P11802,O95067,P14635,Q00534 | Processes and pathways | WikiPathways | msigdb_wp | 65,223,136,317,247,176,142,172,108,242 | 2659,65,2346,172,3250,612,1120,142,108,1402,1812,136,1546,339,223,1260,3027,1627,242,176,779,2490,247,317,3004,1094 | -0.5264977250215082,2.184093386153049,-0.3291314594756453,1.496579247199708,-1.0425353636919736,0.7643892266436848,0.3760035130473384,1.611557358304762,1.764610992500279,0.22000783347747066,-0.014717140094497816,1.6498473485953888,0.14186560484493307,1.1121055878194461,1.3430177439240172,0.2980531923406561,-0.803863386... | 3,643 |
Cell cycle checkpoint signaling | 23 | 70 | 2.981771 | 0.002866 | Q96EA4,Q96RU2,Q16539,Q9UNS1,Q9UN37,P51530,Q92547,Q06124,Q9BX63,P43246,Q9NZJ0,O14757,Q08J23,O43683,O43264,Q13257,P33981,P38398,Q99741,O43670,Q9Y6G9,O60566,P14635 | Processes and pathways | GO Biological process | msigdb_gobp | 401,133,394,280,682,152,37,293,182,417,60,65,68,67,441,580,208,339,228,470,647,356,108 | 65,441,2588,470,67,1729,356,1394,2346,1602,919,3250,1120,2092,108,1402,1812,208,339,417,3027,2677,152,1684,1620,1200,1627,293,68,2308,3189,580,2851,779,735,1980,2941,2489,1209,394,1211,2438,668,2191,1697,2196,2062,37,794,401,2566,2754,3494,2377,133,2961,228,182,1094,1155,902,2461,3052,60,2576,2967,682,280,2519,647 | 2.184093386153049,0.9577701211888938,-0.48697317960573294,0.9191355351926671,2.146041665971875,0.024466452206715977,1.073551824278558,0.22000783347747066,-0.3291314594756453,0.10275757306645614,0.49275464296587623,-1.0425353636919736,0.3760035130473384,-0.17171116116859408,1.764610992500279,0.22000783347747066,-0.01471... | 3,643 |
Trna modification | 20 | 41 | 2.962701 | 0.00305 | Q9NPF4,Q13395,Q9NXG2,Q9H974,Q7Z2T5,Q9NXH9,Q9UBP6,Q32P41,O75648,Q96GJ1,Q08J23,Q2VPK5,Q96EB1,Q9BV44,Q96G46,Q6YHU6,Q9UET6,Q9NX74,Q9UI30,Q6P1R4 | Processes and pathways | GO Biological process | msigdb_gobp | 268,4,406,804,670,807,681,512,141,193,68,836,895,899,896,98,642,903,907,737 | 141,988,1465,1315,1196,2178,68,4,836,512,1076,1696,737,98,1760,670,1144,958,2063,895,896,193,3006,1650,899,3405,1448,804,1583,1452,268,2817,903,406,807,681,642,907,3013,1306,1864 | 1.611557358304762,0.4538605613386647,0.18094894503092676,0.25904250556837555,0.3370401206025548,-0.21102594097074423,2.146041665971875,5.331102366408583,0.5704749577465287,0.8804803264068664,0.4149435883630969,0.06362460524619651,0.6481061483680024,1.8410327378570173,0.024466452206715977,0.7256497757208881,0.3760035130... | 3,643 |
Negative regulation of cell cycle phase transition | 33 | 84 | 2.961277 | 0.003064 | Q96EA4,Q96RU2,Q16539,Q9UNS1,Q9UN37,Q6IQ49,P51530,Q92547,Q15910,Q13535,Q06124,Q9BX63,P43246,Q8N6R0,Q9NZJ0,O14757,Q08J23,O43683,O43264,Q7Z7L1,Q13257,P33981,P38398,Q99741,Q96K76,O43670,Q9Y6G9,O60566,P14635,Q13564,Q969U7,P06400,O00213 | Processes and pathways | GO Biological process | msigdb_gobp | 401,133,394,280,682,668,152,37,784,779,293,182,417,588,60,65,68,67,441,213,580,208,339,228,636,470,647,356,108,735,794,612,605 | 605,65,441,2588,470,67,1729,2828,356,1394,2346,3504,1602,919,3250,612,1120,2092,108,1402,1812,1324,208,339,417,3027,2677,152,1684,1620,1200,1627,293,68,2308,3189,580,2851,779,735,1489,1980,2941,2489,1209,784,394,1211,2438,668,2191,2629,1697,213,1569,2196,588,2062,37,794,1089,401,2566,2754,3494,636,2377,133,2961,228,182... | 0.7643892266436848,2.184093386153049,0.9577701211888938,-0.48697317960573294,0.9191355351926671,2.146041665971875,0.024466452206715977,-0.6452217131559657,1.073551824278558,0.22000783347747066,-0.3291314594756453,-1.5222926203028688,0.10275757306645614,0.49275464296587623,-1.0425353636919736,0.7643892266436848,0.376003... | 3,643 |
Cell cycle | 18 | 58 | 2.956953 | 0.003107 | Q99741,O14757,Q13485,O43683,P33981,Q14674,P25205,P30307,P49841,Q14566,Q12834,P11802,O95067,Q00534,P14635,Q9UBD5,P06400,Q9UJX3 | Processes and pathways | WikiPathways | msigdb_wp | 228,65,188,67,208,294,361,136,475,145,509,142,172,242,108,330,612,64 | 65,67,1729,1237,2975,2828,1602,172,3250,612,1120,142,1732,108,1812,361,1544,1324,2032,136,1256,208,2034,2355,2833,1410,475,1684,1339,620,1685,1826,1627,242,2619,509,1487,733,2851,188,779,1205,1072,145,294,2490,3080,3226,2564,228,1934,330,2390,64,1786,2655,2823,2519 | 2.184093386153049,2.146041665971875,0.024466452206715977,0.2980531923406561,-0.7641668235232126,-0.6452217131559657,0.10275757306645614,1.496579247199708,-1.0425353636919736,0.7643892266436848,0.3760035130473384,1.611557358304762,0.024466452206715977,1.764610992500279,-0.014717140094497816,1.073551824278558,0.141865604... | 3,643 |
Telomere maintenance | 11 | 75 | 2.938544 | 0.003298 | Q5UIP0,O14733,Q8IW41,Q92889,Q9BUR4,P35244,Q96HR8,Q8NDF8,Q9UQ84,O94761,P51530 | Processes and pathways | GO Biological process | msigdb_gobp | 2,183,10,75,148,144,50,124,56,93,152 | 183,2588,3091,1394,2346,93,2772,1539,3583,1245,3093,1468,1732,3367,2777,1320,1402,1542,2226,3436,1057,2227,615,1121,3140,144,1546,1736,1818,3479,2037,1003,2886,3027,1890,1618,152,1620,577,1627,3341,2419,779,2690,457,345,2,10,3318,124,3004,75,793,1573,1089,2754,50,1924,2377,2263,2710,1995,148,2711,593,3405,1518,638,1226... | 1.4582167193470499,-0.48697317960573294,-0.8833276315156983,0.22000783347747066,-0.3291314594756453,1.9173857426024898,-0.605622205270541,0.14186560484493307,-2.0453996779147703,0.2980531923406561,-0.8833276315156983,0.18094894503092676,0.024466452206715977,-1.2021058814321368,-0.605622205270541,0.25904250556837555,0.2... | 3,643 |
Regulation of ubiquitin protein ligase activity | 6 | 15 | 2.936495 | 0.003319 | O00429,Q12834,P61927,O95816,Q96GX5,Q16763 | Processes and pathways | GO Biological process | msigdb_gobp | 97,509,541,357,23,58 | 97,357,2102,1684,1262,541,1898,1482,937,2045,1826,509,580,58,23 | 1.8410327378570173,1.073551824278558,-0.17171116116859408,0.06362460524619651,0.2980531923406561,0.8418043225749562,-0.05392643070728478,0.18094894503092676,0.49275464296587623,-0.132423168996273,-0.014717140094497816,0.8804803264068664,0.8031073486334814,2.2981519715712917,3.0927128631856373 | 3,643 |
Microtubule family cytoskeletal protein | 25 | 57 | 2.933989 | 0.003346 | P52732,Q9BW19,Q14008,Q99661,Q9UN37,Q9BTW9,Q9Y266,Q66K74,Q86Y91,Q13561,Q9Y496,Q96EX3,Q12756,Q14807,O43264,Q3KQU3,Q15058,O43237,O60333,O75449,O94901,Q9Y6G9,P63167,Q5QJ74,O43663 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 870,800,879,675,682,431,171,421,190,456,332,322,941,583,441,226,481,719,720,722,723,647,363,736,608 | 2278,719,441,608,720,722,723,2408,989,1876,1607,1183,1405,1816,1820,870,1063,363,1626,1202,1688,941,2118,456,1425,879,583,481,1490,1564,226,736,421,190,1915,1637,1437,1769,1704,322,1574,3122,1648,675,2962,1516,431,1927,1375,800,1299,2577,1383,682,171,332,647 | -0.2897362923580755,0.6481061483680024,0.9577701211888938,0.7643892266436848,0.6481061483680024,0.6481061483680024,0.6481061483680024,-0.36855296551083955,0.4538605613386647,-0.05392643070728478,0.10275757306645614,0.3370401206025548,0.22000783347747066,-0.014717140094497816,-0.014717140094497816,0.5316260405382865,0.4... | 3,643 |
Protein kinase complex | 9 | 33 | 2.923892 | 0.003457 | O15111,Q96T76,O14920,Q00535,P11802,O95067,Q9Y4W2,P14635,Q00534 | Localization | GO Cellular component | msigdb_gocc | 66,168,221,176,142,172,86,108,242 | 221,66,2286,172,1120,1671,142,1732,2777,1320,2477,108,725,923,1812,1257,1476,310,1410,1336,1197,2842,477,1627,242,176,2425,2320,3351,168,1037,2968,86 | 1.3430177439240172,2.146041665971875,-0.2897362923580755,1.496579247199708,0.3760035130473384,0.06362460524619651,1.611557358304762,0.024466452206715977,-0.605622205270541,0.25904250556837555,-0.4080005745537821,1.764610992500279,0.6481061483680024,0.49275464296587623,-0.014717140094497816,0.2980531923406561,0.18094894... | 3,643 |
Mirna regulation of dna damage response | 10 | 27 | 2.906093 | 0.00366 | O14757,P42574,P30307,Q86UE8,Q7LG56,Q00535,P11802,O95067,P14635,Q00534 | Processes and pathways | WikiPathways | msigdb_wp | 65,223,136,317,247,176,142,172,108,242 | 2659,65,2346,172,3250,612,1120,142,108,1402,1812,136,2833,1546,339,223,1260,3027,1627,242,176,779,2490,247,317,3004,1094 | -0.5264977250215082,2.184093386153049,-0.3291314594756453,1.496579247199708,-1.0425353636919736,0.7643892266436848,0.3760035130473384,1.611557358304762,1.764610992500279,0.22000783347747066,-0.014717140094497816,1.6498473485953888,-0.6452217131559657,0.14186560484493307,1.1121055878194461,1.3430177439240172,0.298053192... | 3,643 |
Toll like receptor tlr1 tlr2 cascade | 21 | 27 | 2.905876 | 0.003662 | Q04206,P28482,Q16539,P51812,P49137,Q14738,P46734,P51617,Q15418,O43318,O14733,P27361,O15111,P51452,Q13616,P09429,P61088,Q16644,Q8IV63,O14920,Q02750 | Processes and pathways | Reactome Pathways | msigdb_reactome | 623,1121,394,13,1002,296,538,290,61,686,183,1057,66,930,1072,818,827,1020,741,221,1012 | 183,221,66,686,2924,818,1057,1121,1408,1122,538,1002,930,290,13,827,1826,1012,623,1072,296,61,2894,394,1020,741,2755 | 1.4582167193470499,1.3430177439240172,2.146041665971875,0.6868888119615674,-0.724494224850264,0.5704749577465287,0.4149435883630969,0.3760035130473384,0.22000783347747066,0.3760035130473384,0.8418043225749562,0.4538605613386647,0.49275464296587623,1.1891538675508655,3.618950764638868,0.5704749577465287,-0.0147171400944... | 3,643 |
Negative regulation of response to dna damage stimulus | 8 | 29 | 2.883062 | 0.003938 | O75832,Q5UIP0,Q8NCN4,Q92889,Q9BRJ7,Q96EB6,Q00613,P14174 | Processes and pathways | GO Biological process | msigdb_gobp | 335,2,227,75,181,349,272,236 | 2154,2666,335,1397,1183,236,2226,1613,272,2308,1980,2941,2429,2,2552,2196,227,75,349,2566,402,636,2377,591,181,1775,3407,752,1527 | -0.21102594097074423,-0.5264977250215082,1.1121055878194461,0.22000783347747066,0.3370401206025548,1.3045804843879147,-0.2503677045331832,0.10275757306645614,1.2276486948314262,-0.2897362923580755,-0.09316168383661999,-0.724494224850264,-0.36855296551083955,6.692085953552384,-0.44747405503507703,-0.21102594097074423,1.... | 3,643 |
Rna modification | 31 | 76 | 2.882553 | 0.003945 | Q9NPF4,Q13395,Q8IZ69,Q9NXG2,Q9H974,Q7L2J0,Q7Z2T5,Q9NXH9,Q9UBP6,Q32P41,O75648,Q96DE0,Q8WVM0,Q96HR8,Q96GJ1,Q6NYC1,Q08J23,Q2VPK5,Q9UJK0,Q9NRW3,Q96EB1,Q9BV44,Q96G46,Q6YHU6,Q9NPE3,Q9UET6,Q96P11,Q9NX74,Q9C0B1,Q6P1R4,Q8IZ73 | Processes and pathways | GO Biological process | msigdb_gobp | 268,4,132,406,804,137,670,807,681,512,141,38,844,50,193,703,68,836,354,352,895,899,896,98,638,642,376,903,114,737,397 | 1310,3091,141,988,1465,2772,1315,2977,3371,1196,2240,2178,68,4,836,512,1565,1076,1696,3266,703,737,1213,98,1760,137,670,1144,1081,1289,3079,132,397,1216,3610,844,958,2705,2063,38,895,896,193,50,376,3006,2265,1650,3353,899,114,3405,1448,804,1583,1098,1224,1452,638,268,352,2817,2270,903,406,807,2079,681,1039,642,907,3013... | 0.25904250556837555,-0.8833276315156983,1.611557358304762,0.4538605613386647,0.18094894503092676,-0.605622205270541,0.25904250556837555,-0.7641668235232126,-1.2021058814321368,0.3370401206025548,-0.2503677045331832,-0.21102594097074423,2.146041665971875,5.331102366408583,0.5704749577465287,0.8804803264068664,0.14186560... | 3,643 |
Sloping forehead | 18 | 57 | 2.876398 | 0.004022 | Q9NPF4,Q08J23,P47897,O43683,Q15058,Q15021,P42695,Q92889,Q9BX63,O43379,O60566,P08243,Q15003,Q00534,Q96KP1,Q6NXR4,Q96EK5,P38398 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 268,68,505,67,481,480,102,75,182,283,356,84,212,242,521,89,590,339 | 1596,1388,1390,283,67,1729,356,2346,2020,1117,1958,84,2296,1056,1328,339,1968,102,505,870,2680,2847,242,68,2116,2118,1071,779,212,480,481,1209,835,626,89,1139,1082,3080,75,1439,2705,2066,590,521,2710,1516,182,1094,2647,3234,2869,1157,268,806,2209,1165,2153 | 0.10275757306645614,0.22000783347747066,0.22000783347747066,1.1891538675508655,2.146041665971875,0.024466452206715977,1.073551824278558,-0.3291314594756453,-0.132423168996273,0.3760035130473384,-0.09316168383661999,1.9936709544036635,-0.2897362923580755,0.4149435883630969,0.25904250556837555,1.1121055878194461,-0.09316... | 3,643 |
Meiotic cell cycle | 18 | 62 | 2.871231 | 0.004089 | Q08J23,O43683,P33981,Q9Y620,Q14674,Q15021,O14965,P42695,P30307,Q92889,Q9BX63,O43264,O60566,O95347,O95067,Q96GX5,Q9UQ84,Q15003 | Processes and pathways | GO Biological process | msigdb_gobp | 68,67,208,100,294,480,468,102,136,75,182,441,356,383,172,23,56,212 | 468,441,67,1729,2828,356,1394,2346,723,172,383,3416,1405,1812,2227,3254,1408,136,208,1882,102,3479,2036,3027,694,1684,2238,2890,1895,3259,3260,68,2115,509,294,2490,2054,212,480,1209,702,1081,3004,75,1704,23,3384,1648,1516,2330,182,1094,1931,679,1032,1454,2577,1861,56,2823,1167,100 | 0.9191355351926671,0.9577701211888938,2.146041665971875,0.024466452206715977,-0.6452217131559657,1.073551824278558,0.22000783347747066,-0.3291314594756453,0.6481061483680024,1.496579247199708,1.034978100199594,-1.2820237758068287,0.22000783347747066,-0.014717140094497816,-0.2503677045331832,-1.0425353636919736,0.220007... | 3,643 |
Trna methylation | 11 | 20 | 2.864451 | 0.004177 | Q6YHU6,Q08J23,Q13395,Q7Z2T5,Q9UET6,Q9NXH9,Q9UBP6,Q32P41,O75648,Q96GJ1,Q9BV44 | Processes and pathways | GO Biological process | msigdb_gobp | 98,68,4,670,642,807,681,512,141,193,899 | 141,2178,68,4,512,98,1760,670,1144,2063,193,1650,899,1452,807,681,642,907,3013,1306 | 1.611557358304762,-0.21102594097074423,2.146041665971875,5.331102366408583,0.8804803264068664,1.8410327378570173,0.024466452206715977,0.7256497757208881,0.3760035130473384,-0.132423168996273,1.4582167193470499,0.10275757306645614,0.5316260405382865,0.22000783347747066,0.6093015947704223,0.7256497757208881,0.76438922664... | 3,643 |
T cell receptor signaling pathway | 12 | 25 | 2.860076 | 0.004235 | Q04206,O15111,O14733,O14920,Q16539,O00221,P49841,P22681,P11802,P19174,Q9UHD1,Q9UDY8 | Processes and pathways | KEGG Pathways | msigdb_kegg | 623,66,183,221,394,101,475,143,142,52,531,563 | 101,183,221,66,686,2348,2923,142,2294,52,143,1057,1121,1815,475,2681,936,2891,1012,623,1560,1634,394,563,531 | 1.8028305179868904,1.4582167193470499,1.3430177439240172,2.146041665971875,0.6868888119615674,-0.3291314594756453,-0.724494224850264,1.611557358304762,-0.2897362923580755,2.3361396571918536,1.611557358304762,0.4149435883630969,0.3760035130473384,-0.014717140094497816,0.9191355351926671,-0.5264977250215082,0.49275464296... | 3,643 |
Cytosolic ribosome | 49 | 78 | 2.852498 | 0.004338 | P62266,P83881,P62753,Q9NP64,P62917,P46782,P42766,P62701,P51116,Q9BY44,P63173,P60866,P39023,P35268,P08708,P62857,P27635,Q9Y3U8,P62750,P62277,P62847,P62269,P46778,P61927,P61254,P18621,P47914,P63220,P62899,P46779,P61513,P62841,P18077,P61247,P83731,P62244,Q02543,Q02878,P62854,Q7Z478,P25398,P62241,P46776,P49207,P36578,P6291... | Localization | GO Cellular component | msigdb_gocc | 621,1011,622,267,1266,869,503,1265,1006,1447,508,1262,1001,1258,1399,271,771,566,1419,1417,662,1416,288,541,1200,1184,824,452,451,1193,696,937,820,1066,578,1067,830,831,344,1025,337,1340,473,1333,1329,241,992,240,121 | 1877,3179,2476,1399,2412,992,820,2480,1184,1613,337,1881,771,1814,2097,1258,1329,2611,1001,1475,503,473,2102,288,1193,1737,869,2175,824,1333,1822,1006,1262,1066,1200,240,1896,696,541,1898,1340,1067,2111,1415,621,1416,1417,2487,2044,1265,1419,622,1482,937,662,1741,344,271,1625,451,2112,241,2045,1266,508,452,578,1011,121... | -0.05392643070728478,-0.9628854457235239,-0.4080005745537821,0.22000783347747066,-0.36855296551083955,0.4538605613386647,0.5704749577465287,-0.4080005745537821,0.3370401206025548,0.10275757306645614,1.1121055878194461,-0.05392643070728478,0.6093015947704223,-0.014717140094497816,-0.17171116116859408,0.2980531923406561,... | 3,643 |
Hdr through homologous recombination hrr | 9 | 31 | 2.816372 | 0.004857 | O14757,Q9NR33,Q92547,Q9BX63,P35244,Q9UQ84,Q14191,P38398,P51530 | Processes and pathways | Reactome Pathways | msigdb_reactome | 65,404,37,182,144,56,457,339,152 | 65,2588,1394,2346,1732,1402,2227,823,144,2356,2536,1546,339,2035,773,1971,3027,152,1620,2177,1270,779,457,37,3004,556,182,404,1779,56,1591 | 2.184093386153049,-0.48697317960573294,0.22000783347747066,-0.3291314594756453,0.024466452206715977,0.22000783347747066,-0.2503677045331832,0.5704749577465287,1.611557358304762,-0.3291314594756453,-0.44747405503507703,0.14186560484493307,1.1121055878194461,-0.132423168996273,0.6093015947704223,-0.09316168383661999,-0.8... | 3,643 |
Zinc finger, RING/FYVE/PHD-type [IPR013083] | 28 | 79 | 2.807221 | 0.004997 | Q8IWS0,Q96T51,O15344,Q9H000,Q14527,P45974,P22681,O75150,Q9Y314,Q7Z3T8,Q99728,Q12933,Q8N2W9,Q8TDB6,Q149N8,Q63HN8,Q99590,Q5W0B1,P29083,Q9NYA4,P19474,Q14139,P38398,Q8NCN4,Q9UPN9,Q92576,Q7Z569,Q9UBS8 | Sequence | InterPro Superfamily | interpro_homologous_superfamily | 516,265,498,676,258,504,143,22,684,273,556,455,191,203,584,315,76,199,445,81,574,211,339,227,644,519,123,529 | 1662,498,650,22,3364,1396,3588,2021,2471,864,1666,1241,1538,1321,574,143,445,1474,339,1819,504,3479,1197,3034,1485,732,1749,455,1561,211,1016,258,1906,584,1019,2743,2995,199,315,2746,273,123,1505,3267,516,191,789,227,203,3447,2806,519,2906,1575,2326,265,1848,2327,76,556,1851,676,965,3010,2271,81,2009,529,1782,3326,2273... | 0.06362460524619651,0.8804803264068664,0.7256497757208881,3.0927128631856373,-1.2021058814321368,0.22000783347747066,-2.1261701689752903,-0.132423168996273,-0.4080005745537821,0.5316260405382865,0.06362460524619651,0.2980531923406561,0.14186560484493307,0.25904250556837555,0.8031073486334814,1.611557358304762,0.9577701... | 3,643 |
Meiotic cell cycle process | 16 | 46 | 2.80603 | 0.005016 | Q08J23,O43683,Q9Y620,Q15021,Q14674,O14965,P42695,P30307,Q92889,Q9BX63,O60566,O95347,O95067,Q96GX5,Q15003,P33981 | Processes and pathways | GO Biological process | msigdb_gobp | 68,67,100,480,294,468,102,136,75,182,356,383,172,23,212,208 | 468,67,2828,356,1394,723,172,383,3416,1405,3254,1408,136,208,1882,102,3479,2036,3027,694,1684,2238,2890,1895,3259,3260,68,2115,509,294,212,480,1209,3004,75,23,3384,2330,182,1094,1931,1032,1454,1861,1167,100 | 0.9191355351926671,2.146041665971875,-0.6452217131559657,1.073551824278558,0.22000783347747066,0.6481061483680024,1.496579247199708,1.034978100199594,-1.2820237758068287,0.22000783347747066,-1.0425353636919736,0.22000783347747066,1.6498473485953888,1.3814361078072093,-0.05392643070728478,1.8028305179868904,-1.402062766... | 3,643 |
Catalytic activity acting on a trna | 26 | 67 | 2.805221 | 0.005028 | Q13395,P47897,Q9H974,Q7Z2T5,Q9NXH9,Q9UBP6,Q32P41,O75648,P54136,Q9BQ52,Q96GW9,Q9BTE6,Q96GJ1,Q08J23,P49589,Q99575,Q5T160,Q9BV44,Q5JPH6,O75818,Q96G46,A2RTX5,Q9NSD9,Q9UET6,Q9C0B1,Q6P1R4 | Functions | GO Molecular function | msigdb_gomf | 4,505,804,670,807,681,512,141,775,710,55,851,193,68,693,744,88,899,483,334,896,220,639,642,114,737 | 220,1234,1392,141,334,2163,990,1401,1471,1543,1056,1191,1616,505,1196,693,3102,1738,775,1338,2418,2178,1341,68,4,2426,2622,1907,512,483,1076,949,88,1696,737,2554,1760,670,1144,1290,896,193,55,744,710,851,899,1653,114,1854,2332,1448,804,3604,1938,639,3277,903,807,1719,681,642,3053,1724,3089,3090,1864 | 1.3430177439240172,0.2980531923406561,0.22000783347747066,1.611557358304762,1.1121055878194461,-0.21102594097074423,0.4538605613386647,0.22000783347747066,0.18094894503092676,0.14186560484493307,0.4149435883630969,0.3370401206025548,0.10275757306645614,0.8804803264068664,0.3370401206025548,0.6868888119615674,-0.8833276... | 3,643 |
Ub specific processing proteases | 32 | 83 | 2.804543 | 0.005039 | P61289,Q92530,Q96RU2,Q14145,P45974,Q13546,P28070,Q06323,Q12834,Q9UL46,Q9Y277,Q86UV5,O00233,P25789,P45880,Q12933,O43318,Q13485,P40818,O75832,Q9Y4E8,Q96K76,P51665,Q9HAW4,P60900,Q8TAF3,Q13309,O00487,Q14694,P51784,O43242,Q96FW1 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,791,133,6,504,257,255,256,509,811,18,275,381,770,287,455,686,188,446,335,99,636,728,902,731,518,733,606,365,238,862,402 | 1597,2219,381,606,1112,862,686,1176,1796,335,3281,1665,3250,991,2027,994,3475,865,1407,1188,770,1323,255,2228,1473,1545,2298,446,2415,287,504,2235,3287,1335,2358,728,238,1198,1261,731,129,1201,2110,1481,256,509,455,943,733,188,257,6,2311,365,1273,1017,3399,2894,1278,275,2902,518,3447,791,1991,2258,1292,1573,402,636,133... | 0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,0.5316260405382865,0.6868888119615674,0.3370401206025548,-0.014717140094497816,1.1121055878194461,-1.0823944165347616,0.06362460524619651,-1.0425353636919736,0.4538605613386647,-0.132423168996273,0.4538605613386647,-1.402062... | 3,643 |
Telomere organization | 11 | 78 | 2.792939 | 0.005223 | Q5UIP0,O14733,Q8IW41,Q92889,Q9BUR4,Q96HR8,P35244,Q8NDF8,Q9UQ84,P51530,O94761 | Processes and pathways | GO Biological process | msigdb_gobp | 2,183,10,75,148,50,144,124,56,152,93 | 183,2588,3091,1394,2346,93,2772,1539,3583,1245,3093,1468,1732,3367,2777,1320,1402,1542,2226,3436,1057,2227,615,1121,3140,144,1546,1736,1818,3479,2037,1003,2886,3027,1890,1618,152,1620,3106,577,1627,3341,2419,779,2690,457,345,784,2,10,3318,124,2062,3004,75,793,1573,1089,2754,50,1924,2377,2263,2710,1995,148,2711,593,3405... | 1.4582167193470499,-0.48697317960573294,-0.8833276315156983,0.22000783347747066,-0.3291314594756453,1.9173857426024898,-0.605622205270541,0.14186560484493307,-2.0453996779147703,0.2980531923406561,-0.8833276315156983,0.18094894503092676,0.024466452206715977,-1.2021058814321368,-0.605622205270541,0.25904250556837555,0.2... | 3,643 |
Protein kinase activity | 38 | 121 | 2.787948 | 0.005304 | Q9BUB5,Q16539,Q8IW41,Q9H4A3,Q13546,P51812,P49761,Q14012,P11802,Q8TD19,Q9BVS4,Q96GX5,Q96SB4,Q8WZ42,Q9BRS2,O14976,P51617,O76075,Q00535,Q9Y3S1,Q15418,O14757,O15111,O14733,O43683,P46020,Q13501,Q86UE8,Q86Y07,P33981,O14920,O14965,P27708,P49841,P54646,O60566,Q96KB5,Q00534 | Functions | GO Molecular function | msigdb_gomf | 403,394,10,11,257,13,506,510,142,552,278,23,555,427,430,408,290,49,176,196,61,65,66,183,67,310,70,317,487,208,221,468,472,475,477,356,520,242 | 183,65,2725,3174,221,1388,468,408,66,1662,686,67,356,2345,1536,1395,2286,3505,49,687,2091,2289,1120,2411,3060,1317,3137,3180,142,3367,3542,2606,1248,1249,1812,3605,3098,1057,472,1121,3183,1815,208,1126,1476,1969,310,538,1259,1002,506,1005,475,1336,290,13,1684,2842,477,1899,1742,1627,242,176,1012,1745,777,1423,1560,1561... | 1.4582167193470499,2.184093386153049,-0.566047472031465,-0.9628854457235239,1.3430177439240172,0.22000783347747066,0.9191355351926671,0.9963842539114091,2.146041665971875,0.06362460524619651,0.6868888119615674,2.146041665971875,1.073551824278558,-0.3291314594756453,0.14186560484493307,0.22000783347747066,-0.28973629235... | 3,643 |
Recombinational repair | 16 | 71 | 2.784664 | 0.005358 | O14757,Q5UIP0,Q9Y620,Q96T76,P49916,Q92889,P46063,Q14566,Q9BUR4,Q9UNS1,P35244,Q8TAF3,P25205,Q14191,P38398,O94761 | Processes and pathways | GO Biological process | msigdb_gobp | 65,2,100,168,7,75,537,145,148,280,144,518,361,457,339,93 | 2154,606,65,2588,2828,2666,1394,2346,1602,93,2288,3533,1468,1402,2226,2608,361,1677,2227,2034,2355,2833,144,2779,339,1736,537,3479,1410,7,3027,1620,1552,827,1895,2308,457,145,546,2626,1428,2,2123,2438,2056,2552,3116,1357,3318,518,75,3161,2263,168,1652,148,2911,2138,2460,3407,1656,855,2007,2819,280,3087,2578,2466,1385,2... | -0.21102594097074423,0.7643892266436848,2.184093386153049,-0.48697317960573294,-0.6452217131559657,-0.5264977250215082,0.22000783347747066,-0.3291314594756453,0.10275757306645614,1.9173857426024898,-0.2897362923580755,-1.6828890806212184,0.18094894503092676,0.22000783347747066,-0.2503677045331832,-0.48697317960573294,1... | 3,643 |
Tcr signaling | 29 | 54 | 2.784112 | 0.005367 | Q04206,Q92530,P61289,P20618,P41240,P28070,Q06323,Q9UL46,O00233,P25789,Q9UDY8,P62191,P49427,P19174,O43318,P25788,O15111,Q13200,Q13616,P61088,Q15008,O75832,P51665,O14920,P60900,O00487,O14818,O43242,P25786 | Processes and pathways | Reactome Pathways | msigdb_reactome | 623,791,129,994,1126,255,256,811,381,770,563,1201,418,52,686,1188,66,943,1072,827,1017,335,728,221,731,606,1112,862,865 | 1597,2219,381,606,1112,221,66,862,686,335,2348,2294,2027,52,994,865,1407,1188,770,1323,255,2228,1473,2298,1126,2415,2235,418,1335,2358,728,1261,731,827,129,1201,2110,1481,1826,623,256,1560,943,1072,1273,1017,1634,2953,791,1577,2068,563,811,1861 | 0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,1.3430177439240172,2.146041665971875,0.5316260405382865,0.6868888119615674,1.1121055878194461,-0.3291314594756453,-0.2897362923580755,-0.132423168996273,2.3361396571918536,0.4538605613386647,0.5316260405382865,0.220007833477... | 3,643 |
Damaged dna binding | 14 | 34 | 2.7825 | 0.005394 | P27695,P26583,P29372,P20585,Q92889,P09429,P52701,P18074,Q14191,P43246,P35244,Q6IQ49,P38398,O94761 | Functions | GO Molecular function | msigdb_gomf | 615,309,414,575,75,818,694,725,457,417,144,668,339,93 | 2346,93,818,1732,2777,1320,1807,1402,725,2226,923,575,1613,309,2227,615,823,414,144,339,1736,417,694,1620,1549,3144,2308,2184,457,1982,668,75,2263,2710 | -0.3291314594756453,1.9173857426024898,0.5704749577465287,0.024466452206715977,-0.605622205270541,0.25904250556837555,-0.014717140094497816,0.22000783347747066,0.6481061483680024,-0.2503677045331832,0.49275464296587623,0.8031073486334814,0.10275757306645614,1.1506395499979194,-0.2503677045331832,0.7643892266436848,0.57... | 3,643 |
G2 m checkpoints | 35 | 95 | 2.780794 | 0.005423 | P61289,Q92530,P30307,P28070,Q14566,Q06323,Q9UL46,P35244,P40938,O00233,Q99728,P25789,P51530,Q92547,Q13535,Q9BX63,O95067,Q9UQ84,Q9UBD5,Q14191,Q8N2W9,O14757,P61088,P38398,Q99741,O75832,P51665,Q7L590,Q9HAW4,P60900,O00487,P14635,P25205,O43242,P62258 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,791,136,255,145,256,811,144,773,381,556,770,152,37,779,182,172,56,330,457,191,65,827,339,228,335,728,890,902,731,606,108,361,862,620 | 1597,2219,381,606,65,1112,862,1237,2975,1394,2346,1602,335,172,2409,1538,3250,1120,108,1402,2027,994,1812,361,865,1407,1188,770,1544,2227,1323,255,2228,1473,136,1256,2034,2355,2833,144,2356,2536,2298,339,2035,773,2415,2235,1335,2358,1410,3027,152,728,1620,1261,731,827,129,1339,1201,2110,620,1481,3106,1685,2619,256,2308... | 0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,2.184093386153049,0.3760035130473384,0.5316260405382865,0.2980531923406561,-0.7641668235232126,0.22000783347747066,-0.3291314594756453,0.10275757306645614,1.1121055878194461,1.496579247199708,-0.36855296551083955,0.14186560484493307,-1.0425353... | 3,643 |
Trna methyltransferase activity | 9 | 13 | 2.774105 | 0.005535 | Q08J23,Q13395,Q7Z2T5,Q9UET6,Q9NXH9,Q9UBP6,Q32P41,O75648,Q96GJ1 | Functions | GO Molecular function | msigdb_gomf | 68,4,670,642,807,681,512,141,193 | 141,2178,68,4,512,1760,670,1144,193,899,807,681,642 | 1.611557358304762,-0.21102594097074423,2.146041665971875,5.331102366408583,0.8804803264068664,0.024466452206715977,0.7256497757208881,0.3760035130473384,1.4582167193470499,0.5316260405382865,0.6093015947704223,0.7256497757208881,0.7643892266436848 | 3,643 |
Ribonucleoside monophosphate biosynthetic process | 8 | 22 | 2.768154 | 0.005637 | P27708,P00492,P00813,P49915,Q01433,O76075,Q9BZX2,O15067 | Processes and pathways | GO Biological process | msigdb_gobp | 472,385,411,476,389,49,351,184 | 184,49,385,411,1669,1672,1319,995,1252,1964,472,1679,867,1123,1614,476,618,1553,389,1745,1130,351 | 1.4582167193470499,2.3741115925465395,1.034978100199594,0.9963842539114091,0.06362460524619651,0.06362460524619651,0.25904250556837555,0.4538605613386647,0.2980531923406561,-0.09316168383661999,0.9191355351926671,0.06362460524619651,0.5316260405382865,0.3760035130473384,0.10275757306645614,0.9191355351926671,0.76438922... | 3,643 |
Regulation of mitotic cell cycle phase transition | 44 | 107 | 2.761989 | 0.005745 | P27695,P61289,Q96EA4,Q7L2J0,P30307,Q06323,Q9UL46,P11802,Q9UN37,Q9BVS4,Q6IQ49,Q9NQW6,Q92547,Q14674,Q15910,Q96QE3,Q9NZJ0,Q9UJX3,O14757,Q9NYL9,O43683,O43264,Q7Z7L1,Q13257,P33981,Q13618,Q9P258,P38398,Q99741,Q15058,Q96K76,P23921,O14965,O43670,Q7LG56,P18074,Q9Y6G9,Q15398,O60566,O95905,P14635,Q13564,Q969U7,P06400 | Processes and pathways | GO Biological process | msigdb_gobp | 615,129,401,137,136,256,811,142,682,278,668,434,37,294,784,591,60,64,65,598,67,441,213,580,208,582,754,339,228,481,636,222,468,470,247,725,647,370,356,358,108,735,794,612 | 2156,65,468,441,2588,3450,470,67,1729,2828,356,2345,1394,2346,358,1667,3250,2924,612,1120,142,2092,108,1402,725,923,222,1812,615,1324,2032,136,1124,208,2414,339,3027,2677,2105,1197,1684,1620,2238,1200,129,1627,1743,1070,256,1487,3189,580,2851,735,582,2184,1489,294,481,370,1209,784,1982,1211,2438,668,2191,2629,1697,137,... | -0.21102594097074423,2.184093386153049,0.9191355351926671,0.9577701211888938,-0.48697317960573294,-1.3620283590937732,0.9191355351926671,2.146041665971875,0.024466452206715977,-0.6452217131559657,1.073551824278558,-0.3291314594756453,0.22000783347747066,-0.3291314594756453,1.073551824278558,0.06362460524619651,-1.04253... | 3,643 |
Catalytic activity acting on dna | 35 | 99 | 2.761491 | 0.005754 | P27695,Q92900,Q9NR33,Q9NRG0,P49916,Q14527,Q14566,Q9H4L7,Q2NKX8,P51530,Q9UPY3,P29372,Q66K74,P26358,P46063,Q9BX63,O76075,P43246,Q9UQ84,Q9HCK8,Q14191,Q96QE3,Q92889,P52701,Q15185,O94761,Q9Y620,Q96FZ2,O14981,Q9C0B1,P18074,Q96RR1,Q12873,Q8NDF8,P25205 | Functions | GO Molecular function | msigdb_gomf | 615,793,404,5,7,258,145,559,153,152,565,414,421,536,537,182,49,417,56,713,457,591,75,694,345,93,100,105,607,114,725,377,732,124,361 | 2156,1868,607,2588,3057,3091,49,93,2166,1400,3137,3416,1732,2777,1320,1807,1054,725,821,2226,923,1613,361,536,615,823,3024,414,2034,2355,2833,2356,2536,1546,1059,1736,2035,773,417,537,3479,1410,7,3027,152,2786,694,1620,2177,3259,1270,3422,1690,1485,732,944,457,881,258,145,1906,345,1428,153,421,1500,2319,2371,3461,1026,... | -0.21102594097074423,-0.05392643070728478,0.7643892266436848,-0.48697317960573294,-0.8435837193418066,-0.8833276315156983,2.3741115925465395,1.9173857426024898,-0.21102594097074423,0.22000783347747066,-0.9230949351912728,-1.2820237758068287,0.024466452206715977,-0.605622205270541,0.25904250556837555,-0.0147171400944978... | 3,643 |
Insulin signaling | 19 | 51 | 2.760819 | 0.005766 | Q16539,P51812,P22681,O14654,P11166,Q9H4M9,Q06124,P46734,Q96PE3,P49815,Q9Y496,Q15418,O43318,O14733,O60343,Q6ZWJ1,O14920,P49841,P54646 | Processes and pathways | WikiPathways | msigdb_wp | 394,13,143,150,653,169,293,538,179,419,332,61,686,183,207,629,221,475,477 | 3449,2016,2969,1308,150,183,221,1113,686,207,2527,2091,2289,688,1805,653,1675,3542,769,1676,2482,143,1057,1121,1815,1816,1476,1969,1192,538,419,1005,475,13,477,1129,2891,1483,2545,1012,293,1629,3398,61,1210,394,629,179,1772,169,332 | -1.3620283590937732,-0.132423168996273,-0.7641668235232126,0.25904250556837555,1.5732494325114137,1.4582167193470499,1.3430177439240172,0.3760035130473384,0.6868888119615674,1.3814361078072093,-0.44747405503507703,-0.17171116116859408,-0.2897362923580755,0.6868888119615674,-0.014717140094497816,0.7256497757208881,0.063... | 3,643 |
Protein kinase, ATP binding site [IPR017441] | 19 | 67 | 2.75314 | 0.005903 | Q9BUB5,Q16539,P49761,P51812,Q14012,P11802,Q96SB4,P51617,Q00535,Q15418,O14757,O15111,O43683,Q86UE8,P33981,O14965,P49841,P54646,Q00534 | Sequence | InterPro Binding site | interpro_binding_site | 403,394,506,13,510,142,555,290,176,61,65,66,67,317,208,468,475,477,242 | 65,468,66,686,67,1536,687,2091,2289,1120,2411,3060,1317,142,3367,3542,2606,1248,1249,1812,3605,1057,1121,3183,1815,208,1126,1476,538,1259,1002,506,1005,475,1336,290,13,1684,477,1742,242,176,1012,1423,1560,1632,878,2425,510,833,2801,61,1634,1279,394,1020,2367,1141,317,2754,2376,555,1578,403,1710,1718,1784 | 2.184093386153049,0.9191355351926671,2.146041665971875,0.6868888119615674,2.146041665971875,0.14186560484493307,0.6868888119615674,-0.17171116116859408,-0.2897362923580755,0.3760035130473384,-0.36855296551083955,-0.8435837193418066,0.25904250556837555,1.611557358304762,-1.2021058814321368,-1.7230890308303868,-0.4869731... | 3,643 |
Interleukin 1 signaling | 29 | 51 | 2.752324 | 0.005917 | Q04206,Q92530,P61289,P20618,P28070,Q06323,Q9UL46,O00233,P25789,P62191,P51617,O43318,P25788,O15111,Q13501,Q13200,P09429,Q13616,P61088,Q15008,O75832,P51665,O14920,P60900,Q02750,O00487,O14818,O43242,P25786 | Processes and pathways | Reactome Pathways | msigdb_reactome | 623,791,129,994,255,256,811,381,770,1201,290,686,1188,66,70,943,818,1072,827,1017,335,728,221,731,1012,606,1112,862,865 | 1597,2219,381,606,1112,221,66,862,686,335,2924,818,2027,994,865,1407,1188,770,1323,255,2228,1473,2298,2415,2235,1335,2358,290,728,1261,731,827,129,1201,2110,1481,1826,1012,623,256,943,70,1072,1273,1017,2894,791,1577,2068,811,1861 | 0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,1.3430177439240172,2.146041665971875,0.5316260405382865,0.6868888119615674,1.1121055878194461,-0.724494224850264,0.5704749577465287,-0.132423168996273,0.4538605613386647,0.5316260405382865,0.22000783347747066,0.3370401206025... | 3,643 |
Nonsense mediated decay nmd | 53 | 87 | 2.751595 | 0.005931 | Q92900,P62266,P83881,P62753,P62917,P46782,P42766,P62701,P63173,P60866,P39023,P35268,P15170,P08708,P62857,P27635,Q9Y3U8,P62750,P62495,P62277,P62847,P62269,P62263,P46778,P61927,P61254,Q9Y5S9,P18621,P63151,P47914,P63220,P62899,P46779,P61513,P11940,P62841,Q04637,P18077,P61247,P83731,P62244,Q02543,Q02878,P62854,P25398,P6224... | Processes and pathways | Reactome Pathways | msigdb_reactome | 793,621,1011,622,1266,869,503,1265,508,1262,1001,1258,386,1399,271,771,566,1419,1418,1417,662,1416,1415,288,541,1200,717,1184,187,824,452,451,1193,696,1318,937,1070,820,1066,578,1067,830,831,344,337,1340,473,1333,1329,241,992,240,121 | 3179,2476,1399,2412,1318,386,992,820,2480,1184,1613,337,1881,771,1814,1408,2097,1258,1329,2983,2611,1001,1475,503,473,2102,288,1193,1737,869,2175,824,1333,1822,1262,1066,1200,240,1896,696,541,1898,1340,1067,2111,1415,621,1416,1417,2487,2044,1418,1265,1419,622,1482,937,662,1741,344,271,1624,1625,451,2112,241,2045,1266,1... | -0.9628854457235239,-0.4080005745537821,0.22000783347747066,-0.36855296551083955,0.25904250556837555,1.034978100199594,0.4538605613386647,0.5704749577465287,-0.4080005745537821,0.3370401206025548,0.10275757306645614,1.1121055878194461,-0.05392643070728478,0.6093015947704223,-0.014717140094497816,0.22000783347747066,-0.... | 3,643 |
Ligase | 22 | 83 | 2.751342 | 0.005935 | P05166,P47897,Q9UBS8,P49916,P22681,Q86UK7,Q96J02,Q14679,P48506,Q96PU5,Q96GW9,Q8TDB6,Q9NT62,Q4G176,P38398,Q5JPH6,Q7Z6Z7,Q9NSD9,P48507,Q9NYK5,A0AVT1,O95352 | Drugs and Diseases | Pharos Drug Target Ontology | pharos_dto | 0,505,529,7,143,274,305,295,173,323,55,203,218,482,339,483,630,639,224,117,604,233 | 604,1392,3209,2163,2471,233,1666,1465,1801,2882,0,990,2167,1540,1401,3569,821,1964,1612,143,1471,1543,867,3065,339,1191,1616,505,173,224,2840,693,3102,1738,2486,7,929,1826,938,735,1072,1693,2184,295,2622,1907,482,483,2554,1286,630,274,1290,956,203,845,55,3383,305,323,2324,1515,1653,1150,676,1934,3464,3604,1655,805,1938... | 0.7643892266436848,0.22000783347747066,-1.0026989814648815,-0.21102594097074423,-0.4080005745537821,1.3045804843879147,0.06362460524619651,0.18094894503092676,-0.014717140094497816,-0.6848457877873478,10.062206007592744,0.4538605613386647,-0.21102594097074423,0.14186560484493307,0.22000783347747066,-1.8840880820322177,... | 3,643 |
Transferase activity transferring one carbon groups | 32 | 80 | 2.744343 | 0.006063 | Q86X55,Q13395,Q8IZ69,Q7L2J0,Q7Z2T5,P22061,Q9NXH9,Q9UBP6,Q32P41,O75648,Q9NZJ6,Q9HBK9,Q15022,Q15910,P26358,O76075,Q8WVM0,Q5T280,Q99707,Q8N6R0,Q96GJ1,Q08J23,P34896,Q99873,Q6P2P2,Q9BV44,P27708,O60678,Q9UET6,Q96P11,Q9H7B4,P04818 | Functions | GO Molecular function | msigdb_gomf | 131,4,132,137,670,135,807,681,512,141,26,432,781,784,536,49,844,459,850,588,193,68,691,592,316,899,472,721,642,376,126,235 | 980,3329,1310,1114,721,1051,1797,141,49,1538,235,2483,135,2977,1252,536,472,1614,691,2980,3371,2178,3185,3034,1745,68,4,1272,1562,781,1633,2694,784,512,1430,459,2745,316,2192,1760,137,1355,670,1144,3526,1081,2747,1289,131,3079,132,1216,588,3380,2062,844,2705,193,3384,1575,376,850,592,899,3572,1855,126,1096,2573,432,109... | 0.4538605613386647,-1.1621798444446965,0.25904250556837555,0.3760035130473384,0.6481061483680024,0.4149435883630969,-0.014717140094497816,1.611557358304762,2.3741115925465395,0.14186560484493307,1.3045804843879147,-0.4080005745537821,1.6498473485953888,-0.7641668235232126,0.2980531923406561,0.8418043225749562,0.9191355... | 3,643 |
Dna binding transcription factor activity | 19 | 40 | 2.741422 | 0.006117 | Q04206,O75569,Q00613,P31260,P85037,Q9BX63,P42224,Q9NXV6,Q6P1N0,P40763,O95747,Q13485,Q15365,Q92766,Q12948,P49711,P51858,Q06546,Q96RE7 | Functions | GO Molecular function | msigdb_gomf | 623,500,272,655,663,182,416,328,460,692,687,188,198,490,103,474,729,110,796 | 2972,2404,500,687,1605,3250,2350,1677,866,655,692,416,474,2105,729,2544,663,2793,1203,272,623,2244,110,1830,103,188,198,460,2951,1987,844,490,1295,796,2961,182,3051,328,1945,1725 | -0.7641668235232126,-0.36855296551083955,0.8804803264068664,0.6868888119615674,0.10275757306645614,-1.0425353636919736,-0.3291314594756453,0.06362460524619651,0.5316260405382865,0.7256497757208881,0.6868888119615674,0.9963842539114091,0.9191355351926671,-0.17171116116859408,0.6481061483680024,-0.44747405503507703,0.725... | 3,643 |
Endonuclease activity | 11 | 43 | 2.737539 | 0.00619 | Q96DE0,Q92889,Q96F86,Q9BRJ7,Q9Y2L1,O76075,Q9BQG2,Q9Y4W2,Q9UQ84,Q9UK59,P51530 | Functions | GO Molecular function | msigdb_gomf | 38,75,178,181,355,49,350,86,56,232,152 | 3017,1234,2588,2161,334,49,2022,2226,1613,615,1736,3027,152,1893,1341,1559,944,881,1563,1428,1352,2318,3004,75,38,178,2710,744,848,710,350,181,1579,2646,2713,232,2392,973,565,56,355,3566,86 | -0.8038633863877657,0.2980531923406561,-0.48697317960573294,-0.21102594097074423,1.1121055878194461,2.3741115925465395,-0.132423168996273,-0.2503677045331832,0.10275757306645614,0.7643892266436848,0.024466452206715977,-0.8038633863877657,1.5732494325114137,-0.05392643070728478,0.25904250556837555,0.14186560484493307,0.... | 3,643 |
Negative regulation of ubiquitin protein transferase activity | 6 | 15 | 2.733487 | 0.006267 | Q8TDB6,Q12834,P61927,O60566,O95816,Q9UL15 | Processes and pathways | GO Biological process | msigdb_gobp | 203,509,541,356,357,29 | 1729,356,357,2102,1262,541,1898,1482,937,2045,509,580,203,1444,29 | 0.024466452206715977,1.073551824278558,1.073551824278558,-0.17171116116859408,0.2980531923406561,0.8418043225749562,-0.05392643070728478,0.18094894503092676,0.49275464296587623,-0.132423168996273,0.8804803264068664,0.8031073486334814,1.4198357192420223,0.22000783347747066,2.828581783531681 | 3,643 |
Rig i like receptor signaling pathway | 9 | 14 | 2.732124 | 0.006293 | Q04206,O15111,O43318,Q13526,Q86UT6,O14920,Q16539,Q13546,Q12933 | Processes and pathways | KEGG Pathways | msigdb_kegg | 623,66,686,130,892,221,394,257,455 | 2156,221,66,686,623,455,130,257,1016,394,1837,1913,892,1784 | -0.21102594097074423,1.3430177439240172,2.146041665971875,0.6868888119615674,0.7643892266436848,0.9577701211888938,1.688119532883408,1.266124183862369,0.4538605613386647,1.034978100199594,-0.014717140094497816,-0.05392643070728478,0.5316260405382865,0.024466452206715977 | 3,643 |
Tcell antigen receptor tcr pathway during staphylococcus aureus infection | 8 | 18 | 2.722874 | 0.006472 | O15111,O14733,O14920,P49841,P22681,P11802,P19174,Q9UHD1 | Processes and pathways | WikiPathways | msigdb_wp | 66,183,221,475,143,142,52,531 | 183,221,66,686,1731,2348,142,2294,52,143,1057,475,2891,1012,2430,1634,563,531 | 1.4582167193470499,1.3430177439240172,2.146041665971875,0.6868888119615674,0.024466452206715977,-0.3291314594756453,1.611557358304762,-0.2897362923580755,2.3361396571918536,1.611557358304762,0.4149435883630969,0.9191355351926671,-0.6848457877873478,0.4538605613386647,-0.36855296551083955,0.10275757306645614,0.841804322... | 3,643 |
Atm signaling in development and disease | 6 | 25 | 2.719119 | 0.006546 | O14757,Q5UIP0,O43683,Q00535,O75150,Q15257 | Processes and pathways | WikiPathways | msigdb_wp | 65,2,67,176,22,367 | 65,67,2346,22,2475,2925,1120,1673,1969,419,3027,932,1627,176,2308,1561,779,2489,2490,2185,367,2,2995,3004,2754 | 2.184093386153049,2.146041665971875,-0.3291314594756453,3.0927128631856373,-0.4080005745537821,-0.724494224850264,0.3760035130473384,0.06362460524619651,-0.09316168383661999,0.9963842539114091,-0.8038633863877657,0.49275464296587623,0.10275757306645614,1.496579247199708,-0.2897362923580755,0.14186560484493307,0.6093015... | 3,643 |
Gastrointestinal carcinoma | 17 | 36 | 2.701078 | 0.006912 | Q13485,O43683,P62899,Q9Y620,O14965,Q8NFG4,P42766,P62847,P52701,P18077,P63167,P43246,O60566,P62857,P62854,Q14191,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 188,67,451,100,468,202,503,662,694,820,363,417,356,271,344,457,240 | 468,67,356,2923,3250,1399,3367,820,823,3140,2611,503,417,2102,2175,694,1262,1200,240,1896,1898,1067,662,344,271,451,2045,363,2048,1270,1423,188,457,2366,202,100 | 0.9191355351926671,2.146041665971875,1.073551824278558,-0.724494224850264,-1.0425353636919736,0.22000783347747066,-1.2021058814321368,0.5704749577465287,0.5704749577465287,-0.9230949351912728,-0.48697317960573294,0.8804803264068664,0.9963842539114091,-0.17171116116859408,-0.21102594097074423,0.6868888119615674,0.298053... | 3,643 |
microtubule binding motor protein | 14 | 24 | 2.691409 | 0.007115 | P52732,Q9BW19,Q15058,Q12756,O60333,Q13561,Q14807,Q8NCM8,Q99661,Q9H0B6,Q07866,Q86Y91,Q9Y496,Q9UJW0 | Functions | Panther Protein class | panther_protein_class | 870,800,481,941,720,456,583,14,675,749,454,190,332,31 | 2278,720,2921,2408,989,1816,870,1688,454,941,456,1833,583,481,190,14,1769,3122,675,800,749,1299,31,332 | -0.2897362923580755,0.6481061483680024,-0.724494224850264,-0.36855296551083955,0.4538605613386647,-0.014717140094497816,0.5316260405382865,0.06362460524619651,0.9577701211888938,0.49275464296587623,0.9577701211888938,-0.014717140094497816,0.8031073486334814,0.9191355351926671,1.4582167193470499,3.581448559077415,0.0244... | 3,643 |
Tolllike receptor signaling pathway | 9 | 17 | 2.686801 | 0.007214 | Q04206,O15111,O14733,O14920,Q16539,Q13546,P46734,P51617,P42224 | Processes and pathways | WikiPathways | msigdb_wp | 623,66,183,221,394,257,538,290,416 | 183,221,66,686,1057,1121,1815,416,538,290,1483,1012,623,257,2894,394,1784 | 1.4582167193470499,1.3430177439240172,2.146041665971875,0.6868888119615674,0.4149435883630969,0.3760035130473384,-0.014717140094497816,0.9963842539114091,0.8418043225749562,1.1891538675508655,0.18094894503092676,0.4538605613386647,0.7643892266436848,1.266124183862369,-0.6848457877873478,1.034978100199594,0.024466452206... | 3,643 |
Toll like receptor signaling pathway | 9 | 17 | 2.686801 | 0.007214 | Q04206,O15111,O14733,O14920,Q16539,Q13546,P46734,P51617,P42224 | Processes and pathways | KEGG Pathways | msigdb_kegg | 623,66,183,221,394,257,538,290,416 | 183,221,66,686,1057,1121,1815,416,538,290,1483,1012,623,257,2894,394,1784 | 1.4582167193470499,1.3430177439240172,2.146041665971875,0.6868888119615674,0.4149435883630969,0.3760035130473384,-0.014717140094497816,0.9963842539114091,0.8418043225749562,1.1891538675508655,0.18094894503092676,0.4538605613386647,0.7643892266436848,1.266124183862369,-0.6848457877873478,1.034978100199594,0.024466452206... | 3,643 |
Dna irdouble strand breaks and cellular response via atm | 7 | 26 | 2.686541 | 0.00722 | O14757,Q5UIP0,P42574,P30307,Q00535,Q00613,Q9UQ84 | Processes and pathways | WikiPathways | msigdb_wp | 65,2,223,136,176,272,56 | 2659,65,2346,3533,3250,1468,1732,136,339,223,3027,1620,1627,176,272,2308,1561,779,2489,2490,2,3004,793,1094,56,2823 | -0.5264977250215082,2.184093386153049,-0.3291314594756453,-1.6828890806212184,-1.0425353636919736,0.18094894503092676,0.024466452206715977,1.6498473485953888,1.1121055878194461,1.3430177439240172,-0.8038633863877657,0.10275757306645614,0.10275757306645614,1.496579247199708,1.2276486948314262,-0.2897362923580755,0.14186... | 3,643 |
Dynein complex | 6 | 13 | 2.685375 | 0.007245 | Q8NCM8,Q9Y6G9,P63167,Q13561,Q9UJW0,Q96EX3 | Localization | GO Cellular component | msigdb_gocc | 14,647,363,456,31,322 | 719,2092,363,2118,456,945,1833,1915,14,322,1574,31,647 | 0.6481061483680024,-0.17171116116859408,1.073551824278558,-0.17171116116859408,0.9577701211888938,0.49275464296587623,-0.014717140094497816,-0.05392643070728478,3.581448559077415,1.1506395499979194,0.14186560484493307,2.752986257481613,0.7643892266436848 | 3,643 |
Regulation of proteasomal ubiquitin dependent protein catabolic process | 15 | 58 | 2.68096 | 0.007341 | O75832,Q14145,Q9Y5A7,O14965,P45974,Q86UE8,P49841,Q9NZL4,P49069,P48506,O95816,Q8NEZ5,Q96KB5,Q9UL15,Q9UBS8 | Processes and pathways | GO Biological process | msigdb_gobp | 335,6,206,468,504,317,475,16,387,173,357,111,520,29,529 | 1867,468,1661,861,1600,1533,335,3588,2771,1666,357,2773,1245,2225,1317,1812,504,2036,173,1259,387,1005,475,3218,1684,1198,1549,3144,2739,1623,1414,2045,1010,1202,875,509,6,2431,317,2196,111,2807,1846,1573,2454,520,1444,676,3407,16,2576,529,29,756,1305,911,206,1790 | -0.05392643070728478,0.9191355351926671,0.06362460524619651,0.5316260405382865,0.10275757306645614,0.14186560484493307,1.1121055878194461,-2.1261701689752903,-0.605622205270541,0.06362460524619651,1.073551824278558,-0.605622205270541,0.2980531923406561,-0.2503677045331832,0.25904250556837555,-0.014717140094497816,0.880... | 3,643 |
Tnfr2 non canonical nf kb pathway | 24 | 44 | 2.677406 | 0.007419 | P61289,Q92530,P20618,P28070,Q06323,Q9UL46,O00233,Q8TBC4,P25789,P62191,Q12933,O15111,P25788,Q13200,Q13616,P61081,Q15008,O75832,P51665,P60900,O00487,O14818,O43242,P25786 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,791,994,255,256,811,381,956,770,1201,455,66,1188,943,1072,935,1017,335,728,731,606,1112,862,865 | 1597,2219,381,606,1112,66,862,335,2027,994,865,1407,1188,770,1323,255,2228,1473,2298,2415,2235,1335,2358,728,1261,731,935,129,1201,2110,1481,1826,256,455,943,1072,1273,1017,956,791,1577,2068,811,1861 | 0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,2.146041665971875,0.5316260405382865,1.1121055878194461,-0.132423168996273,0.4538605613386647,0.5316260405382865,0.22000783347747066,0.3370401206025548,0.6093015947704223,0.25904250556837555,1.266124183862369,-0.250367704533... | 3,643 |
RNA methyltransferase | 10 | 19 | 2.671437 | 0.007553 | Q08J23,Q8IZ69,Q13395,Q7Z2T5,Q9UET6,Q9NXH9,Q8WVM0,Q32P41,O75648,Q96GJ1 | Functions | Panther Protein class | panther_protein_class | 68,132,4,670,642,807,844,512,141,193 | 1310,141,68,4,512,1760,670,1144,1081,3079,132,844,2063,193,899,1098,807,642,1950 | 0.25904250556837555,1.611557358304762,2.146041665971875,5.331102366408583,0.8804803264068664,0.024466452206715977,0.7256497757208881,0.3760035130473384,0.4149435883630969,-0.8435837193418066,1.688119532883408,0.5704749577465287,-0.132423168996273,1.4582167193470499,0.5316260405382865,0.4149435883630969,0.60930159477042... | 3,643 |
Leptin signaling pathway | 12 | 30 | 2.668772 | 0.007613 | P40763,Q04206,O15111,P62753,O14920,Q16539,Q06124,P49841,P54646,P19174,P42224,Q15418 | Processes and pathways | WikiPathways | msigdb_wp | 692,623,66,622,221,394,293,475,477,52,416,61 | 2398,221,66,1536,688,3367,1676,52,1057,1121,692,416,1969,1005,475,477,2681,936,622,2891,1483,1012,623,293,1977,1630,1632,61,394,1788 | -0.36855296551083955,1.3430177439240172,2.146041665971875,0.14186560484493307,0.6868888119615674,-1.2021058814321368,0.06362460524619651,2.3361396571918536,0.4149435883630969,0.3760035130473384,0.6868888119615674,0.9963842539114091,-0.09316168383661999,0.4538605613386647,0.9191355351926671,0.9191355351926671,-0.5264977... | 3,643 |
Processing of dna double strand break ends | 15 | 36 | 2.667442 | 0.007643 | O14757,Q92547,Q13535,Q9NY27,Q9BX63,Q9UNS1,P35244,P61088,P40938,Q9UQ84,Q99728,Q14191,P38398,Q8N2W9,P51530 | Processes and pathways | Reactome Pathways | msigdb_reactome | 65,37,779,855,182,280,144,827,773,56,556,457,339,191,152 | 65,1394,2346,2409,1538,1402,1812,2227,144,2356,2536,339,2035,773,3027,152,1620,1552,827,1414,3106,2308,779,457,2489,191,37,3004,556,182,902,2461,3052,855,280,56 | 2.184093386153049,0.22000783347747066,-0.3291314594756453,-0.36855296551083955,0.14186560484493307,0.22000783347747066,-0.014717140094497816,-0.2503677045331832,1.611557358304762,-0.3291314594756453,-0.44747405503507703,1.1121055878194461,-0.132423168996273,0.6093015947704223,-0.8038633863877657,1.5732494325114137,0.10... | 3,643 |
Dectin 1 mediated noncanonical nf kb signaling | 24 | 44 | 2.662908 | 0.007747 | Q04206,Q92530,P61289,P20618,P28070,Q06323,Q9UL46,O00233,Q8TBC4,P25789,P62191,O15111,P25788,Q13200,Q13616,P61081,Q15008,O75832,P51665,P60900,O00487,O14818,O43242,P25786 | Processes and pathways | Reactome Pathways | msigdb_reactome | 623,791,129,994,255,256,811,381,956,770,1201,66,1188,943,1072,935,1017,335,728,731,606,1112,862,865 | 1597,2219,381,606,1112,66,862,335,2027,994,865,1407,1188,770,1323,255,2228,1473,2298,2415,2235,1335,2358,728,1261,731,935,129,1201,2110,1481,1826,623,256,943,1072,1273,1017,956,791,1577,2068,811,1861 | 0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,2.146041665971875,0.5316260405382865,1.1121055878194461,-0.132423168996273,0.4538605613386647,0.5316260405382865,0.22000783347747066,0.3370401206025548,0.6093015947704223,0.25904250556837555,1.266124183862369,-0.250367704533... | 3,643 |
Ribosome | 44 | 73 | 2.659116 | 0.007835 | P62266,P83881,P62753,P62917,P46782,P42766,P62701,P60866,P63173,P39023,P35268,P08708,P62857,P27635,Q9Y3U8,P62750,P62277,P62847,P46778,P61927,P61254,P18621,P47914,P62899,P63220,P46779,P61513,P62841,P18077,P61247,P83731,P62244,Q02543,Q02878,P62854,P25398,P46776,P62241,P49207,P36578,P62910,P84098,P15880,P61313 | Processes and pathways | KEGG Pathways | msigdb_kegg | 621,1011,622,1266,869,503,1265,1262,508,1001,1258,1399,271,771,566,1419,1417,662,288,541,1200,1184,824,451,452,1193,696,937,820,1066,578,1067,830,831,344,337,473,1340,1333,1329,241,121,992,240 | 3179,2476,1399,2412,992,820,2480,1184,1613,337,1881,771,1814,2097,1258,1329,2611,1001,1475,503,473,2102,288,1193,1737,869,2175,824,1333,1822,1262,1066,1200,240,1896,696,541,1898,1340,1067,2111,621,1416,1417,2487,2044,1265,1419,622,1482,937,662,1741,344,271,1624,1625,451,2112,241,2045,1266,508,452,578,1011,121,830,831,2... | -0.9628854457235239,-0.4080005745537821,0.22000783347747066,-0.36855296551083955,0.4538605613386647,0.5704749577465287,-0.4080005745537821,0.3370401206025548,0.10275757306645614,1.1121055878194461,-0.05392643070728478,0.6093015947704223,-0.014717140094497816,-0.17171116116859408,0.2980531923406561,0.25904250556837555,-... | 3,643 |
Abnormal uterus morphology | 12 | 36 | 2.658814 | 0.007842 | O43683,Q9Y620,Q8NFG4,Q92889,P51812,Q8NCM8,Q9BX63,P63167,P43246,O60566,P38398,Q96EX3 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 67,100,202,75,13,14,182,363,417,356,339,322 | 468,1531,1390,67,356,2923,3250,2728,1671,3367,575,2352,823,3140,339,417,13,694,1262,363,1270,2622,2945,2188,2629,2901,14,202,75,322,182,1094,3520,806,1455,100 | 0.9191355351926671,0.14186560484493307,0.22000783347747066,2.146041665971875,1.073551824278558,-0.724494224850264,-1.0425353636919736,-0.566047472031465,0.06362460524619651,-1.2021058814321368,0.8031073486334814,-0.3291314594756453,0.5704749577465287,-0.9230949351912728,1.1121055878194461,0.9963842539114091,3.618950764... | 3,643 |
P body | 17 | 35 | 2.655186 | 0.007926 | Q92900,O75175,Q5PRF9,Q9Y2V2,Q13501,P06730,Q96F86,Q6P2E9,Q14671,Q9NRW3,P19474,P60900,Q96C86,Q9Y333,O75534,Q9BYJ9,P25789 | Localization | GO Cellular component | msigdb_gocc | 793,651,837,35,70,688,178,840,146,352,574,731,85,160,764,557,770 | 1596,3056,3058,651,764,688,3137,2027,574,1407,770,2354,2298,731,2791,2683,70,882,146,837,1351,840,2255,1920,793,85,178,557,3009,1778,352,2146,1104,35,160 | 0.10275757306645614,-0.8435837193418066,-0.8435837193418066,0.7256497757208881,0.6093015947704223,0.6868888119615674,-0.9230949351912728,-0.132423168996273,0.8031073486334814,0.22000783347747066,0.6093015947704223,-0.3291314594756453,-0.2897362923580755,0.6481061483680024,-0.605622205270541,-0.5264977250215082,2.107973... | 3,643 |
Abnormal large intestine morphology | 28 | 84 | 2.653386 | 0.007969 | Q14145,P42766,Q13546,P51812,Q8WX93,P62857,P98170,Q9UPY3,P41227,P62847,P43246,P42224,O43318,Q08J23,O43683,Q13485,P62899,Q8NFG4,P20585,P54277,P62854,P38398,O94761,Q9Y620,O14965,P63167,O60566,P61313 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 6,503,257,13,674,271,664,565,658,662,417,416,686,68,67,188,451,202,575,87,344,339,93,100,468,363,356,240 | 468,2157,686,67,1729,356,2591,3365,93,2348,2923,3212,3250,3624,1399,1400,1671,3367,820,575,2352,823,3025,3140,2536,3099,339,2611,658,416,503,417,2102,2175,1260,3338,1337,13,694,871,1620,87,1262,1200,240,1896,1898,1067,662,344,271,451,2045,363,2544,664,2048,1270,68,1423,1832,188,257,6,2548,2188,834,1209,1210,1982,1428,2... | 0.9191355351926671,-0.21102594097074423,0.6868888119615674,2.146041665971875,0.024466452206715977,1.073551824278558,-0.48697317960573294,-1.2021058814321368,1.9173857426024898,-0.3291314594756453,-0.724494224850264,-1.0026989814648815,-1.0425353636919736,-2.9786296330998923,0.22000783347747066,0.22000783347747066,0.063... | 3,643 |
Protein monoubiquitination | 10 | 25 | 2.646987 | 0.008121 | Q8TDB6,Q5W0B1,P19474,P22681,Q8TAF3,O75150,Q9C0C9,Q86UK7,Q13618,Q9NZJ0 | Processes and pathways | GO Biological process | msigdb_gobp | 203,199,574,143,518,22,326,274,582,60 | 22,3280,574,143,1826,1072,582,2184,1016,1982,2995,199,2629,2857,630,274,2445,518,203,1848,2327,1515,326,60,1040 | 3.0927128631856373,-1.0823944165347616,0.8031073486334814,1.611557358304762,-0.014717140094497816,0.4149435883630969,0.8031073486334814,-0.21102594097074423,0.4538605613386647,-0.09316168383661999,-0.7641668235232126,1.4198357192420223,-0.48697317960573294,-0.6452217131559657,0.7643892266436848,1.2276486948314262,-0.36... | 3,643 |
Positive regulation of proteasomal ubiquitin dependent protein catabolic process | 11 | 32 | 2.646108 | 0.008142 | O75832,Q9Y5A7,Q14145,O14965,P45974,P49841,Q9NZL4,P48506,Q8NEZ5,O95816,Q9UBS8 | Processes and pathways | GO Biological process | msigdb_gobp | 335,206,6,468,504,475,16,173,111,357,529 | 468,1533,335,3588,1666,357,2773,2225,504,173,1259,1005,475,3218,1684,1549,2739,1414,1010,509,6,2431,111,2454,676,16,2576,529,756,1305,911,206 | 0.9191355351926671,0.14186560484493307,1.1121055878194461,-2.1261701689752903,0.06362460524619651,1.073551824278558,-0.605622205270541,-0.2503677045331832,0.8804803264068664,1.496579247199708,0.2980531923406561,0.4538605613386647,0.9191355351926671,-1.0026989814648815,0.06362460524619651,0.14186560484493307,-0.56604747... | 3,643 |
Cyclin a cdk2 associated events at s phase entry | 23 | 46 | 2.646082 | 0.008143 | P06400,P61289,Q92530,P20618,P28070,Q06323,Q9UL46,P11802,O00233,P25789,P62191,P25788,Q13200,Q13616,Q15008,O75832,P51665,P60900,Q13309,O00487,O14818,O43242,P25786 | Processes and pathways | Reactome Pathways | msigdb_reactome | 612,129,791,994,255,256,811,142,381,770,1201,1188,943,1072,1017,335,728,731,733,606,1112,862,865 | 1597,2219,381,606,1112,862,335,612,142,2027,994,1812,865,1407,1188,770,1323,255,2228,1473,1815,2298,2415,2235,1335,2358,728,1197,1261,731,129,1201,2110,1481,1826,256,1690,943,733,1072,1017,791,1577,2068,811,1861 | 0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,0.5316260405382865,1.1121055878194461,0.7643892266436848,1.611557358304762,-0.132423168996273,0.4538605613386647,-0.014717140094497816,0.5316260405382865,0.22000783347747066,0.3370401206025548,0.6093015947704223,0.2590425055... | 3,643 |
Colon cancer | 9 | 16 | 2.645747 | 0.008151 | Q13485,O43683,Q8NFG4,P20585,Q8WX93,P43246,O60566,P54277,P38398 | Drugs and Diseases | Human Phenotype Ontology | msigdb_hp | 188,67,202,575,674,417,356,87,339 | 67,1729,356,3250,1671,575,339,2611,417,694,87,188,1209,1428,202,674 | 2.146041665971875,0.024466452206715977,1.073551824278558,-1.0425353636919736,0.06362460524619651,0.8031073486334814,1.1121055878194461,-0.48697317960573294,0.9963842539114091,0.6868888119615674,1.9555367643787183,1.4582167193470499,0.3370401206025548,0.22000783347747066,1.4198357192420223,0.7256497757208881 | 3,643 |
Base excision repair | 6 | 18 | 2.645454 | 0.008158 | P27695,Q9NR33,P49916,P29372,P09429,P18858 | Processes and pathways | KEGG Pathways | msigdb_kegg | 615,404,7,414,818,821 | 818,1468,1732,1807,821,2226,615,823,414,1736,1971,7,2177,1270,404,1779,1948,1591 | 0.5704749577465287,0.18094894503092676,0.024466452206715977,-0.014717140094497816,0.5704749577465287,-0.2503677045331832,0.7643892266436848,0.5704749577465287,0.9963842539114091,0.024466452206715977,-0.09316168383661999,4.291847410390771,-0.21102594097074423,0.2980531923406561,1.034978100199594,0.024466452206715977,-0.... | 3,643 |
Class i mhc mediated antigen processing presentation | 59 | 128 | 2.645044 | 0.008168 | P61289,Q92530,P60468,Q96ME1,Q14145,Q7Z7E8,Q14999,Q9UBS8,P28070,Q06323,Q12834,Q9UL46,O95486,O00233,Q8TBC4,P25789,O43164,Q96J02,P52888,Q93034,P49427,Q96PU5,Q9Y3I1,Q9C0C9,Q9Y4B6,Q16763,O95487,Q9UJX3,O15111,Q8TDB6,P55786,P68036,Q13200,Q63HN8,Q13867,P09429,P61081,P60059,P19474,P61088,Q13618,Q14139,Q9ULT8,Q9UII4,O75832,Q7Z6Z... | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,791,619,264,6,138,884,529,255,256,509,811,384,381,956,770,650,305,540,845,418,323,860,326,716,58,920,64,66,203,311,938,943,315,698,818,935,934,574,827,582,211,756,496,335,630,728,221,369,368,731,111,604,606,733,886,862,233,865 | 604,2016,1597,2219,381,606,1112,221,66,1727,650,862,3059,335,2471,2771,2023,233,1666,384,920,2409,1959,818,2025,2027,574,994,1612,865,1407,1188,770,3254,2030,1323,255,2228,1473,1678,2609,2032,2298,2415,2235,418,1335,2358,3218,728,540,1007,1261,1823,311,934,619,1413,731,935,1623,827,129,3481,1201,2110,1481,1826,938,1269... | 0.7643892266436848,-0.132423168996273,0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,1.3430177439240172,2.146041665971875,0.024466452206715977,0.7256497757208881,0.5316260405382865,-0.8435837193418066,1.1121055878194461,-0.4080005745537821,-0.605622205270541,-0.132423168... | 3,643 |
Ranklrank signaling pathway | 9 | 22 | 2.64378 | 0.008199 | O15111,O14733,Q13501,O14920,Q16539,P22681,P19174,P42224,O95340 | Processes and pathways | WikiPathways | msigdb_wp | 66,183,70,221,394,143,52,416,151 | 183,221,66,686,151,3060,3367,52,143,1057,1121,1815,416,1969,2681,1483,1012,623,455,70,2894,394 | 1.4582167193470499,1.3430177439240172,2.146041665971875,0.6868888119615674,1.5732494325114137,-0.8435837193418066,-1.2021058814321368,2.3361396571918536,1.611557358304762,0.4149435883630969,0.3760035130473384,-0.014717140094497816,0.9963842539114091,-0.09316168383661999,-0.5264977250215082,0.18094894503092676,0.4538605... | 3,643 |
Ubiquitin like protein ligase activity | 24 | 61 | 2.642636 | 0.008226 | Q9H000,Q14527,P22681,O75150,Q9Y314,Q86UK7,P98170,Q96J02,Q96PU5,Q9C0C9,Q8N2W9,Q8TDB6,Q149N8,Q63HN8,P19474,Q14139,Q13618,Q9ULT8,Q9UII4,Q7Z6Z7,Q8IVV7,Q15386,Q7Z569,Q9UBS8 | Functions | GO Molecular function | msigdb_gomf | 676,258,143,22,684,274,664,305,323,326,191,203,584,315,574,211,582,756,496,630,372,369,123,529 | 1662,22,987,1396,3588,2021,2471,2771,1397,864,1666,2409,1321,574,143,2103,2681,1623,664,1269,1749,582,211,1016,258,2429,584,369,2436,2995,315,2746,1758,2194,123,3267,630,274,2059,372,191,789,203,1087,305,323,1848,2327,326,676,2002,965,2271,3357,529,496,756,2967,1305,684,911 | 0.06362460524619651,3.0927128631856373,0.4538605613386647,0.22000783347747066,-2.1261701689752903,-0.132423168996273,-0.4080005745537821,-0.605622205270541,0.22000783347747066,0.5316260405382865,0.06362460524619651,-0.36855296551083955,0.25904250556837555,0.8031073486334814,1.611557358304762,-0.17171116116859408,-0.526... | 3,643 |
Hdr through single strand annealing ssa | 8 | 21 | 2.639742 | 0.008297 | Q92547,Q92889,Q9BX63,P35244,Q9UQ84,Q14191,P38398,P51530 | Processes and pathways | Reactome Pathways | msigdb_reactome | 37,75,182,144,56,457,339,152 | 1394,2346,1402,2227,144,2356,2536,339,2035,773,3027,152,1620,779,457,37,3004,75,556,182,56 | 0.22000783347747066,-0.3291314594756453,0.22000783347747066,-0.2503677045331832,1.611557358304762,-0.3291314594756453,-0.44747405503507703,1.1121055878194461,-0.132423168996273,0.6093015947704223,-0.8038633863877657,1.5732494325114137,0.10275757306645614,0.6093015947704223,0.9577701211888938,2.5637384998763477,-0.76416... | 3,643 |
Regulation of mitotic nuclear division | 18 | 49 | 2.636185 | 0.008384 | O14757,Q96EA4,Q13526,O43683,O14965,Q14674,O43670,P30307,O43264,Q15398,Q9Y6G9,O60566,P14635,Q69YH5,Q13257,P33981,Q13618,Q9UJX3 | Processes and pathways | GO Biological process | msigdb_gobp | 65,401,130,67,468,294,470,136,441,370,647,356,108,346,580,208,582,64 | 980,65,468,441,2588,470,67,1729,2828,356,612,2092,108,2732,2032,136,208,2837,1970,2677,1684,2681,1487,3189,580,130,582,2425,294,884,370,1209,1211,346,1985,3199,794,3403,401,2452,2754,3122,1446,1155,2390,64,1786,2655,647 | 0.4538605613386647,2.184093386153049,0.9191355351926671,0.9577701211888938,-0.48697317960573294,0.9191355351926671,2.146041665971875,0.024466452206715977,-0.6452217131559657,1.073551824278558,0.7643892266436848,-0.17171116116859408,1.764610992500279,-0.566047472031465,-0.132423168996273,1.6498473485953888,1.38143610780... | 3,643 |
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 | 22 | 53 | 2.635249 | 0.008408 | P61289,Q92530,O43242,P28070,Q06323,Q12834,Q9UL46,Q96DE5,O00233,P25789,Q16763,Q9UJX3,Q13200,Q15008,O75832,P51665,O14965,P60900,Q13309,O00487,P06400,P25786 | Processes and pathways | Reactome Pathways | msigdb_reactome | 129,791,862,255,256,509,811,961,381,770,58,64,943,1017,335,728,468,731,733,606,612,865 | 1597,2219,381,606,1112,468,862,335,612,2027,994,865,1407,1188,770,1323,255,2228,1473,2032,2298,2415,2235,1335,2358,728,1684,1261,731,129,1201,2110,1481,256,509,1487,943,733,1273,1017,58,791,961,2754,1577,2068,1934,2390,64,1786,2655,811,1861 | 0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,0.9191355351926671,0.5316260405382865,1.1121055878194461,0.7643892266436848,-0.132423168996273,0.4538605613386647,0.5316260405382865,0.22000783347747066,0.3370401206025548,0.6093015947704223,0.25904250556837555,1.26612418386... | 3,643 |
Neurotrophin signaling pathway | 12 | 36 | 2.627679 | 0.008597 | O14654,O14733,O14920,Q16539,Q06124,O00221,P49841,P51812,P62258,P51617,P19174,Q15418 | Processes and pathways | KEGG Pathways | msigdb_kegg | 150,183,221,394,293,101,475,13,620,290,52,61 | 101,150,183,221,2923,3250,3487,52,1544,1057,1121,1815,1256,1126,1192,1886,1002,475,290,13,931,2681,936,1339,620,2891,1483,1685,1012,623,2619,293,878,61,394,2147 | 1.8028305179868904,1.5732494325114137,1.4582167193470499,1.3430177439240172,-0.724494224850264,-1.0425353636919736,-1.4421183790314047,2.3361396571918536,0.14186560484493307,0.4149435883630969,0.3760035130473384,-0.014717140094497816,0.2980531923406561,0.3760035130473384,0.3370401206025548,-0.05392643070728478,0.453860... | 3,643 |
Ubiquitin specific protease, conserved site [IPR018200] | 9 | 17 | 2.626733 | 0.008621 | O94782,Q8NB14,Q9Y4E8,Q96RU2,P45974,P40818,Q86UV5,Q14694,P51784 | Sequence | InterPro Conserved site | interpro_conserved_site | 128,320,99,133,504,446,275,365,238 | 128,1665,446,504,238,1198,365,275,320,3447,1292,1573,636,133,1101,1166,99 | 1.688119532883408,0.06362460524619651,0.9577701211888938,0.8804803264068664,1.3045804843879147,0.3370401206025548,1.073551824278558,1.2276486948314262,1.1506395499979194,-1.3220153104882866,0.2980531923406561,0.14186560484493307,0.7643892266436848,1.688119532883408,0.4149435883630969,0.3760035130473384,1.84103273785701... | 3,643 |
Interleukin 1 family signaling | 26 | 56 | 2.626171 | 0.008635 | Q04206,Q92530,P61289,P28070,Q06323,Q9UL46,O00233,P25789,Q06124,P51617,P40763,O43318,O15111,Q13501,Q13200,P09429,P61088,Q15008,O75832,P51665,O14920,P60900,Q02750,O00487,O43242,P25786 | Processes and pathways | Reactome Pathways | msigdb_reactome | 623,791,129,255,256,811,381,770,293,290,692,686,66,70,943,818,827,1017,335,728,221,731,1012,606,862,865 | 1597,2219,381,606,1112,221,66,862,686,335,2924,818,2027,994,865,1407,1188,770,1323,255,2228,1473,2298,692,2415,2235,1335,2358,290,728,1261,731,827,129,1201,2110,1481,1826,1012,623,293,256,2850,943,70,1072,1273,1017,2894,791,1577,2068,3125,1784,811,1861 | 0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,1.3430177439240172,2.146041665971875,0.5316260405382865,0.6868888119615674,1.1121055878194461,-0.724494224850264,0.5704749577465287,-0.132423168996273,0.4538605613386647,0.5316260405382865,0.22000783347747066,0.3370401206025... | 3,643 |
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