term
stringlengths
2
121
overlap
int64
6
281
setsize
int64
7
499
score
float64
1.96
10.6
pval
float64
0
0.05
edge
stringlengths
41
1.97k
type
stringclasses
5 values
subtype
stringclasses
24 values
subtype_key
stringclasses
24 values
edge_idxs
stringlengths
11
1.17k
ann_idxs
stringlengths
19
2.31k
ann_vals
stringlengths
124
9.94k
sig_size
int64
2.2k
3.73k
Membrane lipid metabolic process
20
39
3.336952
0.000847
Q9P035,Q9Y2B2,Q8NCC3,P07602,Q6Y1H2,Q99805,Q9NZJ7,P27544,O95470,P17900,Q06136,P50897,P04062,Q92643,Q96G23,O15269,Q13510,Q16880,Q99735,Q9NZ01
Processes and pathways
GO Biological process
msigdb_gobp
134,139,289,166,172,182,187,61,65,198,200,77,97,359,103,239,121,122,252,127
239,628,2015,65,97,1817,1225,2327,166,3428,866,198,2999,1290,61,1264,77,2206,200,1683,121,122,549,172,389,289,359,481,103,2828,2829,252,182,692,127,187,134,2529,139
1.6059037631322783,0.5326129525524724,-0.2624237136765148,2.767289755156624,2.4693260750464634,-0.1822683354853108,0.06624331600225977,-0.3862322082359554,2.007685211650335,-2.333607799065281,0.29840678518812824,1.794848233650915,-0.7868309696564781,0.029135457235295485,2.7851863493439573,0.04773817048517167,2.685738533107751,-0.3237756446783554,1.794848233650915,-0.12333709979746053,2.270900210400071,2.270900210400071,0.6599073521556105,1.9638504485042398,0.9886001370636728,1.3296137106483024,1.0872927564021313,0.8129896825372822,2.410850833556328,-0.6480246355463081,-0.6480246355463081,1.5201769173547421,1.9083425678170867,0.46724146702283265,2.229971341354025,1.8633490032538682,2.178194878551719,-0.471302155269236,2.1572887559147627
3,447
Endoplasmic reticulum protein containing complex
28
62
3.336756
0.000848
Q8N4V1,Q9BUN8,P49069,Q53GQ0,O43681,P04844,Q8TCJ2,P46977,Q9Y5M8,Q15041,P13674,Q9H0U3,Q9UGP8,P61619,Q9UBU6,Q8TCT9,Q15005,Q969N2,P51571,Q92643,P04843,Q6NTF9,Q9P0I2,P07237,O15269,Q13438,P67812,Q9NPA0
Localization
GO Cellular component
msigdb_gocc
5,135,276,148,531,537,540,174,50,311,569,325,597,336,214,92,349,481,226,359,607,231,626,236,239,500,120,253
239,628,2841,1418,531,3072,1162,607,537,236,569,2248,2845,3077,3313,1471,2635,174,276,1167,226,2369,3391,1880,336,887,120,752,2853,1103,500,1930,1105,349,1890,311,1527,148,231,1448,1745,5,855,1747,540,92,359,2048,481,992,2828,135,325,253,626,897,214,597,2885,1594,50,1186
1.6059037631322783,0.5326129525524724,-0.6707700428550947,-0.027269365976897105,0.6910437992675935,-0.8584195385239018,0.10296527861463395,0.5648593382990243,0.6755089741541659,1.6179929845170453,0.6285012150671874,-0.3444696497798871,-0.6707700428550947,-0.8584195385239018,-1.214219613160026,-0.04627372815783212,-0.5365115565809986,1.9417437419205628,1.3942178014247664,0.10296527861463395,1.6540303882823562,-0.40730404219216754,-1.5231044801746638,-0.20213507046424417,1.156206673163405,0.2810765284904778,2.270900210400071,0.4006592727447067,-0.6707700428550947,0.13930990831158938,0.7677371814906225,-0.2221155959941241,0.13930990831158938,1.115012567814737,-0.20213507046424417,1.237246593120908,-0.06538144972417397,2.0938827725307765,1.6420560339548476,-0.027269365976897105,-0.14287070187912912,4.040872839878629,0.3156532797160656,-0.14287070187912912,0.6755089741541659,2.498239242135206,1.0872927564021313,-0.2624237136765148,0.8129896825372822,0.21089999179645574,-0.6480246355463081,2.167755946996452,1.1969478078787075,1.5201769173547421,0.5487721681964972,0.2810765284904778,1.7250922784124725,0.5968202922124238,-0.6707700428550947,-0.08459375235902318,2.9341371514763055,0.10296527861463395
3,447
Active transmembrane transporter activity
31
74
3.323589
0.000889
O75306,P05141,O43676,P16615,Q9UDW1,P03886,P20020,Q9UBX3,P28288,O95202,P08183,Q96ES6,O75438,P12236,P05023,P51790,Q00325,P55011,O95168,P12235,Q9Y6M9,Q9P0J0,P98194,P13073,Q15388,Q9HD20,P51970,P23634,P53985,P00403,P20674
Functions
GO Molecular function
msigdb_gomf
382,258,8,136,14,146,403,31,287,169,299,431,181,183,309,448,450,449,453,208,86,87,215,89,353,102,484,483,237,245,508
2182,1597,8,2272,763,1327,382,706,181,2117,453,3383,169,2390,568,245,146,1128,309,1969,258,1163,299,1915,578,879,208,183,89,136,3336,403,508,2492,3361,483,287,3345,1009,1231,2924,2130,661,1196,3214,448,749,484,1233,237,449,1076,215,450,829,752,353,1018,3142,1631,966,431,912,1501,102,2835,1117,87,31,14,1253,2743,530,86
-0.3237756446783554,-0.10391188008073553,3.873674680039861,-0.36528796300450794,0.3838188193188344,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,0.8428492678399792,-1.4938226351232837,1.9858304188448097,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,1.237246593120908,-0.24221132899251827,1.4702992943855286,0.10296527861463395,1.2771132720400578,-0.2221155959941241,0.6126954261187706,0.2810765284904778,1.7717381563510717,1.8859120022561358,2.517396848234407,2.1572887559147627,-1.2956536049018468,0.9599094643624182,0.7372535957044981,-0.471302155269236,-1.3791392568827447,0.7979678150313219,1.342624187693322,-1.3232487120310719,0.19313737866175912,0.06624331600225977,-0.7167208001281143,-0.30320435577832683,0.500075572431892,0.0846519922036011,-1.0316061132826644,0.8576880629169049,0.4006592727447067,0.7979678150313219,0.06624331600225977,1.6179929845170453,0.8576880629169049,0.15734332005004562,1.7133407362411066,0.8576880629169049,0.3328168814905901,0.4006592727447067,1.1011786466586961,0.19313737866175912,-0.9315555215226238,-0.10391188008073553,0.2285742779294462,0.9018467708360485,0.2636616261122957,-0.04627372815783212,2.42065765575822,-0.6480246355463081,0.13930990831158938,2.5269406716164067,3.272073939679055,3.7489696574923244,0.06624331600225977,-0.5806822940457038,0.7065124420438686,2.5364613381868493
3,447
Endoplasmic reticulum golgi intermediate compartment
18
50
3.292162
0.000994
P24390,Q13190,Q9Y3A6,Q02818,O15498,Q9Y3B3,O95070,P07237,Q969X5,Q10472,O15258,P49755,P51572,Q15363,Q9Y282,O15260,P80303,Q8N511
Localization
GO Cellular component
msigdb_gocc
0,322,422,38,197,234,171,236,429,305,219,343,404,222,26,88,28,63
219,88,197,1064,171,236,1226,0,3313,827,611,343,2251,404,2498,3306,953,28,38,752,2292,305,1174,322,1526,1527,222,592,602,2607,2216,63,1691,2105,1454,429,1697,911,2001,3105,452,1762,2318,1763,2532,26,422,234,1157,779
1.7015526819939406,2.517396848234407,1.794848233650915,0.15734332005004562,1.9638504485042398,1.6179929845170453,0.06624331600225977,4.529155521859711,-1.214219613160026,0.3328168814905901,0.5648593382990243,1.1287949380852866,-0.3444696497798871,0.9599094643624182,-0.471302155269236,-1.1875123306433095,0.2285742779294462,3.3426079878781034,3.1679674644036484,0.4006592727447067,-0.36528796300450794,1.2505830026120932,0.10296527861463395,1.1969478078787075,-0.06538144972417397,-0.06538144972417397,1.7015526819939406,0.5968202922124238,0.5808751529702354,-0.5146374427323911,-0.3237756446783554,2.776248153122407,-0.12333709979746053,-0.28275422227728697,-0.027269365976897105,0.9018467708360485,-0.12333709979746053,0.2636616261122957,-0.24221132899251827,-0.8826227148684676,0.8576880629169049,-0.14287070187912912,-0.36528796300450794,-0.14287070187912912,-0.471302155269236,3.396631569290751,0.9309929669262402,1.6300436532822637,0.12118423630495645,0.3838188193188344
3,447
Copi mediated anterograde transport
12
58
3.254013
0.001138
P24390,Q9BVA1,Q13190,O95249,O15498,O43731,Q9Y3B3,Q9BUF5,P68371,P04350,Q13885,Q15363
Processes and pathways
Reactome Pathways
msigdb_reactome
0,34,322,66,197,6,234,107,78,47,52,222
780,2621,197,1711,6,2624,745,66,47,2125,0,1337,2791,3153,1725,618,343,1198,2498,1521,2030,1477,711,734,590,78,1480,888,1438,2292,3053,322,1013,1831,2209,52,1104,1784,2143,1526,222,1241,1691,3162,624,3206,3060,107,34,2001,452,1853,2058,2318,1320,234,1157,1187
0.3668988157742944,-0.5365115565809986,1.794848233650915,-0.14287070187912912,3.9547704783957736,-0.5365115565809986,0.4006592727447067,2.7583110565843194,2.9427278149247016,-0.30320435577832683,4.529155521859711,0.010434058495094673,-0.6254296213866243,-0.9562907027938861,-0.14287070187912912,0.5487721681964972,1.1287949380852866,0.0846519922036011,-0.471302155269236,-0.06538144972417397,-0.2624237136765148,-0.04627372815783212,0.4341047300866308,0.4174209793635682,0.5968202922124238,2.685738533107751,-0.04627372815783212,0.2810765284904778,-0.027269365976897105,-0.36528796300450794,-0.8343882553406996,1.1969478078787075,0.19313737866175912,-0.1822683354853108,-0.3237756446783554,2.890903968218817,0.13930990831158938,-0.16251400074754818,-0.30320435577832683,-0.06538144972417397,1.7015526819939406,0.06624331600225977,-0.12333709979746053,-0.9562907027938861,0.5487721681964972,-1.0063130127151403,-0.8343882553406996,2.381281697129018,3.200287370541324,-0.24221132899251827,0.8576880629169049,-0.1822683354853108,-0.2624237136765148,-0.36528796300450794,0.029135457235295485,1.6300436532822637,0.12118423630495645,0.10296527861463395
3,447
Oxidative phosphorylation
20
61
3.215291
0.001303
O75306,P14406,O43676,Q9UDW1,P03886,O75964,O14949,P56134,Q99643,O75438,Q9BSK2,O95168,P24539,P56385,Q9Y6M9,P13073,Q9H3K2,P51970,P61586,P00403
Processes and pathways
GO Biological process
msigdb_gobp
382,1,8,14,146,21,24,405,432,181,76,453,209,337,86,89,225,484,240,245
2182,1597,24,8,2272,1327,382,2274,706,181,2117,2748,21,453,3383,2390,568,245,146,1128,1006,1163,578,1422,879,89,1,1066,1228,922,3336,508,981,209,2847,1819,3345,1291,2495,1009,2592,1617,1618,1196,3406,3214,484,2369,405,337,240,3142,1631,2264,2688,432,76,225,14,1032,86
-0.3237756446783554,-0.10391188008073553,3.411935775289236,3.873674680039861,-0.36528796300450794,0.010434058495094673,1.0028619724328278,-0.36528796300450794,0.4341047300866308,1.9083425678170867,-0.30320435577832683,-0.6029828692428588,3.5692505459608204,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,0.19313737866175912,0.10296527861463395,0.6126954261187706,-0.027269365976897105,0.2810765284904778,2.517396848234407,4.313649129144161,0.15734332005004562,0.06624331600225977,0.2461611801381823,-1.2956536049018468,0.7372535957044981,0.21089999179645574,1.7601302536193415,-0.6707700428550947,-0.1822683354853108,-1.3232487120310719,0.029135457235295485,-0.471302155269236,0.19313737866175912,-0.5146374427323911,-0.10391188008073553,-0.10391188008073553,0.0846519922036011,-1.673164747906431,-1.0316061132826644,0.7979678150313219,-0.40730404219216754,0.9599094643624182,1.1425261705350076,1.6059037631322783,-0.9315555215226238,-0.10391188008073553,-0.3444696497798871,-0.5585258554562905,0.9018467708360485,2.6948832866620145,1.6659669752722266,3.7489696574923244,0.19313737866175912,2.5364613381868493
3,447
Steroid biosynthetic process
20
48
3.214377
0.001307
Q14739,Q14534,Q15800,Q9UBM7,P16435,Q53GQ0,P14324,P28288,Q16850,Q15392,P30536,P05023,P37268,Q15125,O94905,O75845,O76062,Q8NBQ5,P54646,Q13510
Processes and pathways
GO Biological process
msigdb_gobp
128,130,7,400,275,148,402,287,164,40,41,309,199,84,463,357,115,373,375,121
1003,476,357,115,463,1161,309,2246,402,1718,275,1290,2441,2846,287,41,199,1978,1621,1475,750,375,3314,1683,121,2375,130,128,84,2860,40,2721,2263,581,7,164,148,373,2649,3376,971,2962,2735,1500,2003,400,1908,1505
0.19313737866175912,0.8129896825372822,1.0872927564021313,2.2912039487046916,0.8279499860422683,0.10296527861463395,1.237246593120908,-0.3444696497798871,0.9599094643624182,-0.14287070187912912,1.3942178014247664,0.029135457235295485,-0.44983727276622243,-0.6707700428550947,1.342624187693322,3.0360255403392498,1.794848233650915,-0.24221132899251827,-0.10391188008073553,-0.04627372815783212,0.4006592727447067,1.0312209548801738,-1.214219613160026,-0.12333709979746053,2.270900210400071,-0.40730404219216754,2.1886057148305667,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,-0.5806822940457038,-0.3444696497798871,0.6126954261187706,3.9211731425024707,2.0294163563584418,2.0938827725307765,1.045319009782404,-0.5365115565809986,-1.4359917276919325,0.2285742779294462,-0.7399306553991354,-0.5806822940457038,-0.04627372815783212,-0.24221132899251827,0.9742827906130651,-0.20213507046424417,-0.04627372815783212
3,447
Mitochondrial membrane organization
22
44
3.18127
0.001466
Q8IWA4,Q9NS69,P05141,Q5XKP0,Q9Y512,P45880,Q13505,Q9BUR5,Q9Y5J9,O75431,Q53H12,O95202,Q15070,O95140,Q9Y276,P12235,Q6UXV4,Q9P0J0,Q9H3K2,Q9NVH1,Q8WWC4,O60313
Processes and pathways
GO Biological process
msigdb_gobp
256,3,258,137,274,16,407,147,282,413,549,169,53,437,461,208,213,87,225,489,363,365
2066,1372,365,413,2277,437,169,2843,258,708,2584,1971,208,1291,2590,1873,3119,1978,16,2451,612,407,53,3236,558,737,549,137,213,256,2378,2683,363,147,225,3,489,1364,87,1414,461,2180,274,282
-0.28275422227728697,-0.008367163295788871,1.059363369451296,0.9454796834826562,-0.36528796300450794,0.8871862971088242,1.9858304188448097,-0.6707700428550947,1.4702992943855286,0.4341047300866308,-0.5146374427323911,-0.24221132899251827,1.7717381563510717,0.029135457235295485,-0.5146374427323911,-0.20213507046424417,-0.9070004618348723,-0.24221132899251827,3.6994359897329634,-0.44983727276622243,0.5648593382990243,0.9599094643624182,2.8647369895860946,-1.0570912841778808,0.6442383099094389,0.4174209793635682,0.6599073521556105,2.1572887559147627,1.7250922784124725,1.4953208273418972,-0.40730404219216754,-0.5585258554562905,1.0733544735925842,2.1045230542075872,1.6659669752722266,4.276636208213452,0.7979678150313219,0.010434058495094673,2.5269406716164067,-0.008367163295788871,0.8428492678399792,-0.30320435577832683,1.40700578874686,1.3685099847547963
3,447
Organic acid transmembrane transporter activity
8
23
3.176887
0.001489
Q96H78,Q96NB2,P08183,P53985,Q9H2D1,O95563,P30825,Q9UBX3
Functions
GO Molecular function
msigdb_gomf
165,296,299,237,46,269,310,31
666,1003,1669,269,299,1915,310,1231,661,1233,237,829,1018,1450,165,296,1699,46,1501,636,31,1660,329
0.4836959753352828,0.19313737866175912,-0.12333709979746053,1.40700578874686,1.2771132720400578,-0.2221155959941241,1.237246593120908,0.06624331600225977,0.500075572431892,0.06624331600225977,1.6179929845170453,0.3328168814905901,0.19313737866175912,-0.027269365976897105,2.018566145549778,1.3034558937486695,-0.12333709979746053,2.9513000228072084,-0.04627372815783212,0.5326129525524724,3.272073939679055,-0.10391188008073553,1.1834170961274035
3,447
Organic acid transport
19
52
3.172403
0.001512
Q9NP80,P23786,O95563,Q9UBX3,O43772,P28288,Q96H78,Q96NB2,P08183,Q9H2D1,Q15041,P30825,P50416,Q9Y619,P14174,O43808,P53985,O60831,Q7L0J3
Processes and pathways
GO Biological process
msigdb_gobp
398,395,269,31,286,287,165,296,299,46,311,310,316,329,330,347,237,235,123
666,1003,286,347,235,1669,1160,269,842,2668,2121,3091,1714,299,1915,844,330,730,395,287,310,882,2814,1231,661,316,1233,237,449,3407,1389,829,1683,311,649,1018,2762,1450,123,1143,165,296,1699,46,1501,636,398,31,1660,799,1768,329
0.4836959753352828,0.19313737866175912,1.342624187693322,1.115012567814737,1.6179929845170453,-0.12333709979746053,0.10296527861463395,1.40700578874686,0.3156532797160656,-0.5585258554562905,-0.30320435577832683,-0.8826227148684676,-0.14287070187912912,1.2771132720400578,-0.2221155959941241,0.3156532797160656,1.1698368489882653,0.4174209793635682,0.9742827906130651,1.342624187693322,1.237246593120908,0.2810765284904778,-0.6480246355463081,0.06624331600225977,0.500075572431892,1.2238621747785425,0.06624331600225977,1.6179929845170453,0.8576880629169049,-1.673164747906431,-0.008367163295788871,0.3328168814905901,-0.12333709979746053,1.237246593120908,0.5163809909451085,0.19313737866175912,-0.6029828692428588,-0.027269365976897105,2.2607083952402736,0.12118423630495645,2.018566145549778,1.3034558937486695,-0.12333709979746053,2.9513000228072084,-0.04627372815783212,0.5326129525524724,0.9742827906130651,3.272073939679055,-0.10391188008073553,0.3668988157742944,-0.14287070187912912,1.1834170961274035
3,447
Dementia
22
61
3.165731
0.001547
Q9UBB4,Q9NQZ5,P21912,P03886,Q9Y487,O43681,Q8WVX9,P07602,P04350,P61916,O15118,Q9NZJ7,P27544,O76024,Q709C8,P17900,O96008,Q14108,P04062,O60313,P00403,Q13510
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
391,138,270,146,149,531,541,166,47,557,186,187,61,189,583,198,464,93,97,365,245,121
588,186,531,365,1865,189,464,245,146,1128,97,3410,47,1970,2327,166,1716,3290,198,2023,270,1380,1099,61,2495,670,1338,2924,2130,2198,1674,3080,2132,1268,2369,557,2290,2404,1887,2931,121,93,1104,2212,2043,583,833,813,1402,541,1694,1057,2051,2688,2770,138,1090,187,391,1184,149
0.5968202922124238,1.8633490032538682,0.6910437992675935,1.059363369451296,-0.20213507046424417,1.840651870597142,0.8279499860422683,1.5694020954564156,2.1257159606954366,0.12118423630495645,2.4693260750464634,-1.7348868279040783,2.9427278149247016,-0.24221132899251827,-0.3862322082359554,2.007685211650335,-0.14287070187912912,-1.161017467090014,1.794848233650915,-0.2624237136765148,1.40700578874686,-0.008367163295788871,0.13930990831158938,2.7851863493439573,-0.471302155269236,0.4836959753352828,0.010434058495094673,-0.7167208001281143,-0.30320435577832683,-0.3237756446783554,-0.12333709979746053,-0.8584195385239018,-0.30320435577832683,0.04773817048517167,-0.40730404219216754,0.6442383099094389,-0.36528796300450794,-0.4285051553274654,-0.20213507046424417,-0.7167208001281143,2.270900210400071,2.4886252124811126,0.13930990831158938,-0.3237756446783554,-0.2624237136765148,0.6126954261187706,0.3328168814905901,0.349898446135214,-0.008367163295788871,0.6755089741541659,-0.12333709979746053,0.17528547971368946,-0.2624237136765148,-0.5585258554562905,-0.6029828692428588,2.1572887559147627,0.15734332005004562,1.8633490032538682,0.9886001370636728,0.10296527861463395,2.0938827725307765
3,447
Respirasome
22
46
3.163738
0.001558
O75306,P14406,O43676,Q9UDW1,P21912,P03886,O14949,Q9Y241,Q99643,Q96CU9,O75438,O96000,Q9Y276,Q86Y39,O95168,Q9Y6M9,Q9P0J0,P13073,P51970,P00403,P20674,Q13423
Localization
GO Cellular component
msigdb_gocc
382,1,8,14,270,146,24,30,432,180,181,568,461,71,453,86,87,89,484,245,508,255
2182,1597,24,8,2272,1327,382,706,181,2117,453,3383,2390,568,245,146,1128,578,802,879,89,1,1228,922,3336,508,270,981,3345,2495,1009,1196,3214,484,255,3142,1631,1209,71,180,432,87,14,30,461,86
-0.3237756446783554,-0.10391188008073553,3.411935775289236,3.873674680039861,-0.36528796300450794,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,0.6126954261187706,0.349898446135214,0.2810765284904778,2.517396848234407,4.313649129144161,0.06624331600225977,0.2461611801381823,-1.2956536049018468,0.7372535957044981,1.40700578874686,0.21089999179645574,-1.3232487120310719,-0.471302155269236,0.19313737866175912,0.0846519922036011,-1.0316061132826644,0.7979678150313219,1.4953208273418972,-0.9315555215226238,-0.10391188008073553,0.0846519922036011,2.7312521573765434,1.9195087103543416,0.9018467708360485,2.5269406716164067,3.7489696574923244,3.3035742260608005,0.8428492678399792,2.5364613381868493
3,447
Electron transport chain oxphos system in mitochondria
22
52
3.161836
0.001568
O75306,P14406,P05141,O43676,Q9UDW1,P21912,P03886,O75964,O14949,P56134,Q99643,O75438,P12236,O95168,P12235,P24539,P56385,Q9Y6M9,P13073,P51970,P00403,P20674
Processes and pathways
WikiPathways
msigdb_wp
382,1,258,8,14,270,146,21,24,405,432,181,183,453,208,209,337,86,89,484,245,508
2182,1597,24,8,2272,1327,382,706,181,2117,520,2748,21,453,3383,2390,568,245,146,1128,258,1163,802,879,208,183,89,1,1228,922,3336,508,270,981,209,2847,3345,2495,1009,1617,1196,3406,3214,484,405,337,3142,1631,432,14,1414,86
-0.3237756446783554,-0.10391188008073553,3.411935775289236,3.873674680039861,-0.36528796300450794,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,0.7065124420438686,-0.6029828692428588,3.5692505459608204,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,1.4702992943855286,0.10296527861463395,0.349898446135214,0.2810765284904778,1.7717381563510717,1.8859120022561358,2.517396848234407,4.313649129144161,0.06624331600225977,0.2461611801381823,-1.2956536049018468,0.7372535957044981,1.40700578874686,0.21089999179645574,1.7601302536193415,-0.6707700428550947,-1.3232487120310719,-0.471302155269236,0.19313737866175912,-0.10391188008073553,0.0846519922036011,-1.673164747906431,-1.0316061132826644,0.7979678150313219,0.9599094643624182,1.1425261705350076,-0.9315555215226238,-0.10391188008073553,0.9018467708360485,3.7489696574923244,-0.008367163295788871,2.5364613381868493
3,447
Copi dependent golgi to er retrograde traffic
13
50
3.160229
0.001576
P24390,Q9BVA1,Q9P2W9,O43731,Q9Y3B3,Q9BUF5,P68371,P04350,Q13885,Q12981,P49755,O15260,Q15363
Processes and pathways
Reactome Pathways
msigdb_reactome
0,34,68,6,234,107,78,47,52,439,343,88,222
1769,780,88,2841,6,1064,1420,2120,47,2125,0,1616,1337,2791,618,343,2670,2498,1521,2030,711,734,78,888,1680,2085,3157,439,52,1015,222,1448,1241,1691,770,2936,3060,107,34,2001,1755,1456,2380,452,1853,68,2318,234,1593,1157
-0.16251400074754818,0.3668988157742944,2.517396848234407,-0.6707700428550947,3.9547704783957736,0.15734332005004562,-0.027269365976897105,-0.30320435577832683,2.9427278149247016,-0.30320435577832683,4.529155521859711,-0.10391188008073553,0.010434058495094673,-0.6254296213866243,0.5487721681964972,1.1287949380852866,-0.5585258554562905,-0.471302155269236,-0.06538144972417397,-0.2624237136765148,0.4341047300866308,0.4174209793635682,2.685738533107751,0.2810765284904778,-0.12333709979746053,-0.28275422227728697,-0.9562907027938861,0.8871862971088242,2.890903968218817,0.19313737866175912,1.7015526819939406,-0.027269365976897105,0.06624331600225977,-0.12333709979746053,0.3838188193188344,-0.7167208001281143,-0.8343882553406996,2.381281697129018,3.200287370541324,-0.24221132899251827,-0.14287070187912912,-0.027269365976897105,-0.40730404219216754,0.8576880629169049,-0.1822683354853108,2.7583110565843194,-0.36528796300450794,1.6300436532822637,-0.08459375235902318,0.12118423630495645
3,447
Protein insertion into membrane
15
28
3.155252
0.001604
Q15629,Q9NS69,Q8N4V1,Q9Y276,Q8WWC4,Q9Y512,P61619,Q96A33,P49069,P46379,Q15070,Q9P0J0,O43681,Q9Y5J9,Q9NPA0
Processes and pathways
GO Biological process
msigdb_gobp
33,3,5,461,363,274,336,178,276,179,53,87,531,282,253
1372,1418,531,2387,2277,3047,708,2590,1873,179,276,336,1890,53,33,549,1348,5,855,363,178,253,3,626,87,461,274,282
-0.008367163295788871,-0.027269365976897105,0.6910437992675935,-0.4285051553274654,-0.36528796300450794,-0.8343882553406996,0.4341047300866308,-0.5146374427323911,-0.20213507046424417,1.9195087103543416,1.3942178014247664,1.156206673163405,-0.20213507046424417,2.8647369895860946,3.216350650152123,0.6599073521556105,0.010434058495094673,4.040872839878629,0.3156532797160656,1.0733544735925842,1.9306423672509032,1.5201769173547421,4.276636208213452,0.5487721681964972,2.5269406716164067,0.8428492678399792,1.40700578874686,1.3685099847547963
3,447
Membrane lipid biosynthetic process
13
25
3.137929
0.001701
O95470,P04062,Q92643,Q9P035,Q96G23,Q06136,Q9Y2B2,Q6Y1H2,O15269,Q99805,Q13510,Q16880,P27544
Processes and pathways
GO Biological process
msigdb_gobp
65,97,359,134,103,200,139,172,239,182,121,122,61
239,628,2015,65,97,2999,1290,61,2206,200,1683,121,122,549,172,389,359,481,103,2828,182,692,134,2529,139
1.6059037631322783,0.5326129525524724,-0.2624237136765148,2.767289755156624,2.4693260750464634,-0.7868309696564781,0.029135457235295485,2.7851863493439573,-0.3237756446783554,1.794848233650915,-0.12333709979746053,2.270900210400071,2.270900210400071,0.6599073521556105,1.9638504485042398,0.9886001370636728,1.0872927564021313,0.8129896825372822,2.410850833556328,-0.6480246355463081,1.9083425678170867,0.46724146702283265,2.178194878551719,-0.471302155269236,2.1572887559147627
3,447
Sterol biosynthetic process
14
27
3.104312
0.001907
Q14739,Q14534,Q16850,Q15800,Q15392,P37268,O75845,Q9UBM7,P16435,Q15125,O76062,O94905,P14324,P54646
Processes and pathways
GO Biological process
msigdb_gobp
128,130,164,7,40,199,357,400,275,84,115,463,402,375
476,357,115,463,1161,2246,402,275,199,1978,1621,1475,750,375,3314,1683,2375,130,128,84,2860,40,581,7,164,400,1505
0.8129896825372822,1.0872927564021313,2.2912039487046916,0.8279499860422683,0.10296527861463395,-0.3444696497798871,0.9599094643624182,1.3942178014247664,1.794848233650915,-0.24221132899251827,-0.10391188008073553,-0.04627372815783212,0.4006592727447067,1.0312209548801738,-1.214219613160026,-0.12333709979746053,-0.40730404219216754,2.1886057148305667,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,2.0294163563584418,0.9742827906130651,-0.04627372815783212
3,447
Protein localization
33
74
3.071708
0.002128
Q9NS69,P50402,O60830,Q99595,P09601,Q9Y512,Q13505,Q9NR77,Q8N4H5,P49069,O43681,Q9Y5J9,P21796,P51648,O75431,P28288,O43615,P46379,P12236,O15228,Q2T9J0,Q13190,Q9Y276,P12235,Q10713,O96008,O43808,P56589,Q15388,O14925,Q6QHF9,O75381,Q9BY49
Processes and pathways
Reactome Pathways
msigdb_reactome
3,259,4,9,11,274,407,18,20,276,531,282,27,29,413,287,543,179,183,567,317,322,461,208,344,464,347,351,353,106,111,491,385
919,106,1003,567,1599,543,531,2387,347,4,491,3343,413,2971,3137,1669,3304,2277,464,1970,1163,578,3384,11,3248,208,183,2021,27,2441,2847,287,3190,3119,788,682,179,276,259,29,1340,351,3391,344,3438,322,407,663,353,317,737,1742,111,1348,20,1112,2103,1843,9,3037,385,1028,18,3,1364,2529,2839,1660,799,461,1122,1768,274,282
0.2461611801381823,2.391162989421182,0.19313737866175912,0.6285012150671874,-0.10391188008073553,0.6599073521556105,0.6910437992675935,-0.4285051553274654,1.115012567814737,4.1444590074269065,0.7828838337881776,-1.3232487120310719,0.9454796834826562,-0.7632999174742385,-0.9315555215226238,-0.12333709979746053,-1.1875123306433095,-0.36528796300450794,0.8279499860422683,-0.24221132899251827,0.10296527861463395,0.6126954261187706,-1.4938226351232837,3.804859663855004,-1.0827717031939503,1.7717381563510717,1.8859120022561358,-0.2624237136765148,3.3503698232892996,-0.44983727276622243,-0.6707700428550947,1.342624187693322,-1.0063130127151403,-0.9070004618348723,0.3668988157742944,0.46724146702283265,1.9195087103543416,1.3942178014247664,1.4702992943855286,3.3348312629722443,0.010434058495094673,1.1011786466586961,-1.5231044801746638,1.1287949380852866,-3.169413212981655,1.1969478078787075,0.9599094643624182,0.500075572431892,1.1011786466586961,1.2238621747785425,0.4174209793635682,-0.14287070187912912,2.3314960227808297,0.010434058495094673,3.5912373381541602,0.13930990831158938,-0.28275422227728697,-0.1822683354853108,3.8600030048314653,-0.8105262504581725,1.0028619724328278,0.19313737866175912,3.642085390164092,4.276636208213452,0.010434058495094673,-0.471302155269236,-0.6480246355463081,-0.10391188008073553,0.3668988157742944,0.8428492678399792,0.13930990831158938,-0.14287070187912912,1.40700578874686,1.3685099847547963
3,447
Mitochondrial respiratory chain complex assembly
18
37
3.06666
0.002165
O75306,Q9Y276,O43676,Q86Y39,P51970,Q9BSK2,Q9H061,Q9Y512,O95168,Q9Y2R0,P03886,Q69YU5,Q96CU9,O75438,Q15070,Q9Y6M9,Q9P0J0,O43819
Processes and pathways
GO Biological process
msigdb_gobp
382,461,8,71,484,76,13,274,453,17,146,19,180,181,53,86,87,340
2182,8,2272,340,1327,382,181,2117,520,453,2390,824,568,146,1128,3345,1196,484,1885,53,3142,1631,19,1209,71,180,3061,76,2875,13,2656,3039,87,461,17,274,86
-0.3237756446783554,3.873674680039861,-0.36528796300450794,1.1287949380852866,0.010434058495094673,1.0028619724328278,1.9083425678170867,-0.30320435577832683,0.7065124420438686,0.8428492678399792,-0.4285051553274654,0.3328168814905901,0.6285012150671874,2.1257159606954366,0.12118423630495645,-1.3232487120310719,0.0846519922036011,0.7979678150313219,-0.20213507046424417,2.8647369895860946,-0.9315555215226238,-0.10391188008073553,3.605829860637424,0.0846519922036011,2.7312521573765434,1.9195087103543416,-0.8343882553406996,2.6948832866620145,-0.6707700428550947,3.7489696574923244,-0.5365115565809986,-0.8105262504581725,2.5269406716164067,0.8428492678399792,3.656498320463535,1.40700578874686,2.5364613381868493
3,447
Hormone metabolic process
16
28
3.045224
0.002325
O95470,Q8TC12,O75844,P30536,Q6UX07,Q9UBM7,Q9HB40,Q06520,Q8NBN7,P16435,Q53GQ0,Q8NBQ5,P42892,Q9Y394,P05023,Q6NUM9
Processes and pathways
GO Biological process
msigdb_gobp
65,517,58,41,250,400,108,238,112,275,148,373,341,377,309,350
1667,58,65,309,2021,1718,275,41,341,3380,1340,1926,238,2263,148,350,250,112,373,517,2649,2468,2962,108,536,400,1366,377
-0.12333709979746053,2.8295777132185935,2.767289755156624,1.237246593120908,-0.2624237136765148,-0.14287070187912912,1.3942178014247664,3.0360255403392498,1.1287949380852866,-1.4647849416373495,0.010434058495094673,-0.2221155959941241,1.6179929845170453,-0.3444696497798871,2.0938827725307765,1.115012567814737,1.5448699088190703,2.3214620624481643,1.045319009782404,0.7219155083838219,-0.5365115565809986,-0.44983727276622243,-0.7399306553991354,2.36144368763533,0.6910437992675935,0.9742827906130651,0.010434058495094673,1.0312209548801738
3,447
transporter
15
60
3.044295
0.002332
O43772,Q15012,O60830,Q9H2V7,Q9Y619,Q99595,P53985,Q8NFH4,Q9H2D1,Q567V2,Q9NR77,Q15070,Q99805,Q9HD45,Q92544
Functions
Panther Protein class
panther_protein_class
286,32,4,69,329,9,237,173,46,79,18,53,182,156,223
822,2745,726,2887,1811,667,543,531,286,1966,2190,4,2276,669,2447,3322,788,661,1132,3002,1101,3233,2709,1233,237,3028,952,1476,336,524,987,2677,32,53,79,3434,2096,906,173,1308,510,223,1749,704,2827,1903,9,182,3299,1215,46,69,1757,156,18,778,2573,1032,2065,329
0.3328168814905901,-0.6029828692428588,0.4174209793635682,-0.6936680218939302,-0.1822683354853108,0.4836959753352828,0.6599073521556105,0.6910437992675935,1.342624187693322,-0.24221132899251827,-0.3237756446783554,4.1444590074269065,-0.36528796300450794,0.4836959753352828,-0.44983727276622243,-1.241143026979425,0.3668988157742944,0.500075572431892,0.12118423630495645,-0.7868309696564781,0.13930990831158938,-1.0570912841778808,-0.5806822940457038,0.06624331600225977,1.6179929845170453,-0.8105262504581725,0.2285742779294462,-0.04627372815783212,1.156206673163405,0.7065124420438686,0.21089999179645574,-0.5585258554562905,3.224358363615056,2.8647369895860946,2.685738533107751,-2.5135956035021803,-0.28275422227728697,0.2636616261122957,1.9528130358260574,0.029135457235295485,0.7372535957044981,1.6897278697989968,-0.14287070187912912,0.45071130368158374,-0.6480246355463081,-0.20213507046424417,3.8600030048314653,1.9083425678170867,-1.161017467090014,0.0846519922036011,2.9513000228072084,2.749311957797667,-0.14287070187912912,2.0617845088395463,3.642085390164092,0.3838188193188344,-0.49290160023430213,0.19313737866175912,-0.2624237136765148,1.1834170961274035
3,447
Selective autophagy
12
32
3.033852
0.002415
Q8IWA4,Q15388,Q9BVA1,Q9NS69,Q9BUF5,P68371,P04350,Q8N4H5,Q13885,P54646,O95140,P21796
Processes and pathways
Reactome Pathways
msigdb_reactome
256,353,34,3,107,78,47,20,52,375,437,27
1711,605,2277,437,464,47,708,784,1193,1775,27,1102,375,2369,590,1077,78,753,1928,1013,52,1784,353,256,20,3162,1309,2688,107,34,3,1187
-0.14287070187912912,0.5648593382990243,-0.36528796300450794,0.8871862971088242,0.8279499860422683,2.9427278149247016,0.4341047300866308,0.3668988157742944,0.0846519922036011,-0.16251400074754818,3.3503698232892996,0.13930990831158938,1.0312209548801738,-0.40730404219216754,0.5968202922124238,0.15734332005004562,2.685738533107751,0.4006592727447067,-0.2221155959941241,0.19313737866175912,2.890903968218817,-0.16251400074754818,1.1011786466586961,1.4953208273418972,3.5912373381541602,-0.9562907027938861,0.029135457235295485,-0.5585258554562905,2.381281697129018,3.200287370541324,4.276636208213452,0.10296527861463395
3,447
Steroid biosynthesis
12
25
3.03173
0.002432
Q14739,Q16850,Q15800,Q15392,P37268,O75845,Q9UBM7,O76062,Q53GQ0,Q15125,Q8NBQ5,P54646
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
128,164,7,40,199,357,400,115,148,84,373,375
357,115,1161,402,199,1621,750,375,3314,1683,2375,128,84,2860,40,581,7,164,148,373,2649,2735,1500,400,1505
1.0872927564021313,2.2912039487046916,0.10296527861463395,0.9599094643624182,1.794848233650915,-0.10391188008073553,0.4006592727447067,1.0312209548801738,-1.214219613160026,-0.12333709979746053,-0.40730404219216754,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,2.0294163563584418,2.0938827725307765,1.045319009782404,-0.5365115565809986,-0.5806822940457038,-0.04627372815783212,0.9742827906130651,-0.04627372815783212
3,447
Metal ion transmembrane transporter activity
13
25
3.028969
0.002454
P55011,Q8N4V1,Q9H0U3,Q9HD20,Q9Y6M7,O95202,P23634,P16615,P61619,P98194,P20020,P05023,Q9UM00
Functions
GO Molecular function
msigdb_gomf
449,5,325,102,530,169,483,136,336,215,403,309,285
169,309,1969,1329,2541,1915,136,403,483,1677,449,336,215,1779,2142,652,5,966,2222,912,325,102,563,285,530
1.9858304188448097,1.237246593120908,-0.24221132899251827,0.010434058495094673,-0.49290160023430213,-0.2221155959941241,2.1572887559147627,0.9599094643624182,0.7979678150313219,-0.12333709979746053,0.8576880629169049,1.156206673163405,1.7133407362411066,-0.16251400074754818,-0.30320435577832683,0.5163809909451085,4.040872839878629,0.2285742779294462,-0.3237756446783554,0.2636616261122957,1.1969478078787075,2.42065765575822,0.6442383099094389,1.3555894999858193,0.7065124420438686
3,447
Ion transport
26
54
3.023582
0.002498
P0CG08,Q9Y6M7,P16615,P45880,Q9Y487,O75964,P20020,P21796,P56134,Q9UM00,O95202,Q9NVV0,Q93050,Q8NEW0,P05023,P51790,Q4KMQ2,P55011,P24539,P56385,Q9Y277,P98194,O96008,P23634,Q9BVC6,Q8NE01
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
514,530,136,16,149,21,403,27,405,285,169,563,175,55,309,448,323,449,209,337,82,215,464,483,370,379
1909,2748,21,169,464,309,1969,1163,514,136,403,2492,3361,27,483,209,2847,1617,2924,2130,16,3406,448,749,1677,828,449,405,337,1076,215,2142,592,323,3434,2762,652,379,966,55,1143,175,1540,370,2380,1117,563,1253,285,82,149,2743,3273,530
-0.2221155959941241,-0.6029828692428588,3.5692505459608204,1.9858304188448097,0.8279499860422683,1.237246593120908,-0.24221132899251827,0.10296527861463395,0.7219155083838219,2.1572887559147627,0.9599094643624182,-0.471302155269236,-1.3791392568827447,3.3503698232892996,0.7979678150313219,1.7601302536193415,-0.6707700428550947,-0.10391188008073553,-0.7167208001281143,-0.30320435577832683,3.6994359897329634,-1.673164747906431,0.8576880629169049,0.4006592727447067,-0.12333709979746053,0.3328168814905901,0.8576880629169049,0.9599094643624182,1.1425261705350076,0.15734332005004562,1.7133407362411066,-0.30320435577832683,0.5968202922124238,1.1969478078787075,-2.5135956035021803,-0.6029828692428588,0.5163809909451085,1.0170687594342533,0.2285742779294462,2.8559762796306747,0.12118423630495645,1.9417437419205628,-0.06538144972417397,1.059363369451296,-0.40730404219216754,0.13930990831158938,0.6442383099094389,0.06624331600225977,1.3555894999858193,2.6118073444066714,2.0938827725307765,-0.5806822940457038,-1.1086506296557357,0.7065124420438686
3,447
Electron transport
22
49
3.020234
0.002526
O75306,O43169,O43676,Q9UDW1,P21912,P03886,O14949,Q9Y241,O43396,Q99643,Q9H3N1,Q96CU9,O75438,Q9H1E5,O96000,Q86Y39,O95168,Q9Y6M9,Q9P0J0,P51970,P00403,Q16134
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
382,2,8,14,270,146,24,30,542,432,49,180,181,56,568,71,453,86,87,484,245,504
2182,1597,24,2,542,8,2272,1327,382,706,181,2117,453,3383,2390,568,245,146,1128,578,3230,1228,3336,270,2846,981,3345,2495,1009,1874,3171,1196,3214,484,504,3142,1631,2679,1209,71,180,2468,432,56,49,87,14,30,86
-0.3237756446783554,-0.10391188008073553,3.411935775289236,4.307502880587425,0.6599073521556105,3.873674680039861,-0.36528796300450794,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,0.6126954261187706,-1.0570912841778808,0.06624331600225977,-1.2956536049018468,1.40700578874686,-0.6707700428550947,0.21089999179645574,-1.3232487120310719,-0.471302155269236,0.19313737866175912,-0.20213507046424417,-0.9812088834856775,0.0846519922036011,-1.0316061132826644,0.7979678150313219,0.75252729309868,-0.9315555215226238,-0.10391188008073553,-0.5585258554562905,0.0846519922036011,2.7312521573765434,1.9195087103543416,-0.44983727276622243,0.9018467708360485,2.8559762796306747,2.9341371514763055,2.5269406716164067,3.7489696574923244,3.3035742260608005,2.5364613381868493
3,447
Sphingolipid biosynthetic process
10
19
3.006544
0.002642
O95470,P04062,Q9P035,Q96G23,Q06136,Q6Y1H2,Q99805,Q13510,Q16880,P27544
Processes and pathways
GO Biological process
msigdb_gobp
65,97,134,103,200,172,182,121,122,61
239,628,65,97,2999,1290,61,2206,200,1683,121,122,549,172,103,182,692,134,2529
1.6059037631322783,0.5326129525524724,2.767289755156624,2.4693260750464634,-0.7868309696564781,0.029135457235295485,2.7851863493439573,-0.3237756446783554,1.794848233650915,-0.12333709979746053,2.270900210400071,2.270900210400071,0.6599073521556105,1.9638504485042398,2.410850833556328,1.9083425678170867,0.46724146702283265,2.178194878551719,-0.471302155269236
3,447
Establishment of protein localization to membrane
32
89
2.999063
0.002708
Q9NS69,Q8N4V1,Q15907,Q9Y512,P49069,O43681,P43307,Q9Y5J9,P27105,Q15629,Q53H12,Q96A33,Q9UNL2,P46379,Q15070,Q15041,O15118,O60725,P61026,Q9Y276,Q9UGP8,P61619,Q15904,P98194,Q9P0J0,P63244,P56589,Q99442,Q9HD20,Q8WWC4,Q9H4A6,Q9NPA0
Processes and pathways
GO Biological process
msigdb_gobp
3,5,141,274,276,531,25,282,414,33,549,178,434,179,53,311,186,70,580,461,597,336,592,215,87,348,351,360,102,363,251,253
1188,2066,2237,1372,864,186,1418,531,2387,70,1126,2118,2277,842,3047,1969,708,2072,1556,1971,414,2590,1560,882,1873,2128,682,1566,25,179,2791,276,1167,1168,2286,351,3391,2898,1922,580,336,348,215,1779,1438,3053,1576,2983,1890,311,649,53,33,592,141,931,549,1348,2824,2412,2379,5,855,1112,363,178,1057,360,837,251,1905,102,1029,253,3,1116,626,87,597,1318,1763,2429,434,1765,461,1768,1862,274,282
0.0846519922036011,-0.28275422227728697,-0.3444696497798871,-0.008367163295788871,0.29840678518812824,1.8633490032538682,-0.027269365976897105,0.6910437992675935,-0.4285051553274654,2.7312521573765434,0.12118423630495645,-0.30320435577832683,-0.36528796300450794,0.3156532797160656,-0.8343882553406996,-0.24221132899251827,0.4341047300866308,-0.28275422227728697,-0.08459375235902318,-0.24221132899251827,0.9454796834826562,-0.5146374427323911,-0.08459375235902318,0.2810765284904778,-0.20213507046424417,-0.30320435577832683,0.46724146702283265,-0.08459375235902318,3.396631569290751,1.9195087103543416,-0.6254296213866243,1.3942178014247664,0.10296527861463395,0.10296527861463395,-0.36528796300450794,1.1011786466586961,-1.5231044801746638,-0.6936680218939302,-0.2221155959941241,0.6126954261187706,1.156206673163405,1.115012567814737,1.7133407362411066,-0.16251400074754818,-0.027269365976897105,-0.8343882553406996,-0.08459375235902318,-0.7632999174742385,-0.20213507046424417,1.237246593120908,0.5163809909451085,2.8647369895860946,3.216350650152123,0.5968202922124238,2.1362689307517044,0.2461611801381823,0.6599073521556105,0.010434058495094673,-0.6480246355463081,-0.4285051553274654,-0.40730404219216754,4.040872839878629,0.3156532797160656,0.13930990831158938,1.0733544735925842,1.9306423672509032,0.17528547971368946,1.0872927564021313,0.3328168814905901,1.5325436558776693,-0.20213507046424417,2.42065765575822,0.19313737866175912,1.5201769173547421,4.276636208213452,0.13930990831158938,0.5487721681964972,2.5269406716164067,0.5968202922124238,0.029135457235295485,-0.14287070187912912,-0.4285051553274654,0.9018467708360485,-0.14287070187912912,0.8428492678399792,-0.14287070187912912,-0.1822683354853108,1.40700578874686,1.3685099847547963
3,447
Organic acid transmembrane transport
13
32
2.994778
0.002746
O43772,P28288,Q9Y619,Q96NB2,P08183,P53985,Q9H2D1,O60831,O95563,Q15041,P30825,P50416,Q9UBX3
Processes and pathways
GO Biological process
msigdb_gobp
286,287,329,296,299,237,46,235,269,311,310,316,31
286,235,1669,1160,269,3091,299,1915,844,395,287,310,882,2814,1231,661,316,1233,237,829,311,1018,2762,1143,296,1699,46,1501,636,31,1660,329
1.342624187693322,1.6179929845170453,-0.12333709979746053,0.10296527861463395,1.40700578874686,-0.8826227148684676,1.2771132720400578,-0.2221155959941241,0.3156532797160656,0.9742827906130651,1.342624187693322,1.237246593120908,0.2810765284904778,-0.6480246355463081,0.06624331600225977,0.500075572431892,1.2238621747785425,0.06624331600225977,1.6179929845170453,0.3328168814905901,1.237246593120908,0.19313737866175912,-0.6029828692428588,0.12118423630495645,1.3034558937486695,-0.12333709979746053,2.9513000228072084,-0.04627372815783212,0.5326129525524724,3.272073939679055,-0.10391188008073553,1.1834170961274035
3,447
Oxidative phosphorylation
24
61
2.985512
0.002831
O75306,P14406,O43676,Q9UDW1,P21912,P03886,Q9Y487,O75964,O14949,P56134,Q93050,Q99643,O75438,O96000,P08574,Q86Y39,O95168,P24539,P56385,Q9Y6M9,P13073,P51970,P00403,P20674
Processes and pathways
KEGG Pathways
msigdb_kegg
382,1,8,14,270,146,149,21,24,405,175,432,181,568,578,71,453,209,337,86,89,484,245,508
2182,1597,24,8,2272,1327,382,706,181,2117,2748,21,453,3383,2390,568,245,146,1128,1163,578,802,879,89,1,1228,922,3336,508,2492,3361,270,981,209,2847,3345,2495,1009,1617,2924,2130,1196,3406,3214,484,405,337,1076,2719,592,3142,1631,71,175,432,3378,14,1253,149,2743,86
-0.3237756446783554,-0.10391188008073553,3.411935775289236,3.873674680039861,-0.36528796300450794,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,-0.6029828692428588,3.5692505459608204,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,0.10296527861463395,0.6126954261187706,0.349898446135214,0.2810765284904778,2.517396848234407,4.313649129144161,0.06624331600225977,0.2461611801381823,-1.2956536049018468,0.7372535957044981,-0.471302155269236,-1.3791392568827447,1.40700578874686,0.21089999179645574,1.7601302536193415,-0.6707700428550947,-1.3232487120310719,-0.471302155269236,0.19313737866175912,-0.10391188008073553,-0.7167208001281143,-0.30320435577832683,0.0846519922036011,-1.673164747906431,-1.0316061132826644,0.7979678150313219,0.9599094643624182,1.1425261705350076,0.15734332005004562,-0.5806822940457038,0.5968202922124238,-0.9315555215226238,-0.10391188008073553,2.7312521573765434,1.9417437419205628,0.9018467708360485,-1.4359917276919325,3.7489696574923244,0.06624331600225977,2.0938827725307765,-0.5806822940457038,2.5364613381868493
3,447
Retrograde vesicle mediated transport golgi to endoplasmic reticulum
8
27
2.974115
0.002938
P24390,Q9P2W9,O43731,Q969X5,P49755,Q9Y282,Q9H4A6,O15258
Processes and pathways
GO Biological process
msigdb_gobp
0,68,6,429,343,26,251,219
780,219,6,1064,2125,0,1337,2198,618,1132,343,1521,711,1480,888,1174,439,1448,1142,1994,1691,429,624,251,68,2318,26
0.3668988157742944,1.7015526819939406,3.9547704783957736,0.15734332005004562,-0.30320435577832683,4.529155521859711,0.010434058495094673,-0.3237756446783554,0.5487721681964972,0.12118423630495645,1.1287949380852866,-0.06538144972417397,0.4341047300866308,-0.04627372815783212,0.2810765284904778,0.10296527861463395,0.8871862971088242,-0.027269365976897105,0.12118423630495645,-0.24221132899251827,-0.12333709979746053,0.9018467708360485,0.5487721681964972,1.5325436558776693,2.7583110565843194,-0.36528796300450794,3.396631569290751
3,447
Active ion transmembrane transporter activity
18
40
2.965721
0.00302
P13073,P51790,Q00325,P05141,P55011,P98194,Q9HD20,O95202,P23634,P16615,Q9UDW1,Q96ES6,P12235,P00403,P12236,P20020,P05023,P20674
Functions
GO Molecular function
msigdb_gomf
89,448,450,258,449,215,102,169,483,136,14,431,208,245,183,403,309,508
169,245,309,1969,258,1163,1915,578,879,208,183,89,136,403,508,2492,3361,483,1009,1231,2924,2130,661,1196,448,749,1233,449,1076,215,450,829,431,912,1501,102,14,1253,2743,530
1.9858304188448097,1.5694020954564156,1.237246593120908,-0.24221132899251827,1.4702992943855286,0.10296527861463395,-0.2221155959941241,0.6126954261187706,0.2810765284904778,1.7717381563510717,1.8859120022561358,2.517396848234407,2.1572887559147627,0.9599094643624182,0.7372535957044981,-0.471302155269236,-1.3791392568827447,0.7979678150313219,0.19313737866175912,0.06624331600225977,-0.7167208001281143,-0.30320435577832683,0.500075572431892,0.0846519922036011,0.8576880629169049,0.4006592727447067,0.06624331600225977,0.8576880629169049,0.15734332005004562,1.7133407362411066,0.8576880629169049,0.3328168814905901,0.9018467708360485,0.2636616261122957,-0.04627372815783212,2.42065765575822,3.7489696574923244,0.06624331600225977,-0.5806822940457038,0.7065124420438686
3,447
Sphingolipid metabolism
11
26
2.963766
0.003039
O95470,P04062,P07602,P17900,Q06136,Q96G23,P51648,Q13510,Q16880,Q9NZJ7,P27544
Processes and pathways
Reactome Pathways
msigdb_reactome
65,97,166,198,200,103,29,121,122,187,61
587,239,628,531,2626,65,97,1225,2327,166,3428,843,866,198,1290,61,29,200,121,122,103,2829,2734,692,187,2529
0.5968202922124238,1.6059037631322783,0.5326129525524724,0.6910437992675935,-0.5365115565809986,2.767289755156624,2.4693260750464634,0.06624331600225977,-0.3862322082359554,2.007685211650335,-2.333607799065281,0.3156532797160656,0.29840678518812824,1.794848233650915,0.029135457235295485,2.7851863493439573,3.3348312629722443,1.794848233650915,2.270900210400071,2.270900210400071,2.410850833556328,-0.6480246355463081,-0.5806822940457038,0.46724146702283265,1.8633490032538682,-0.471302155269236
3,447
Golgi cisterna
14
25
2.95083
0.003169
O95249,O00461,P0CG08,Q96L58,Q9P2E5,Q8WVQ1,Q16706,Q10472,Q10713,Q8TBA6,P98194,P51572,Q15363,Q9H4A6
Localization
GO Cellular component
msigdb_gocc
66,36,514,390,460,457,593,305,344,247,215,404,222,251
36,66,1162,514,404,215,3217,2292,1575,305,344,1832,222,593,1349,247,1994,457,624,390,1797,251,460,1764,2177
3.184159827888789,2.7583110565843194,0.10296527861463395,0.7219155083838219,0.9599094643624182,1.7133407362411066,-1.0316061132826644,-0.36528796300450794,-0.08459375235902318,1.2505830026120932,1.1287949380852866,-0.1822683354853108,1.7015526819939406,0.5968202922124238,0.010434058495094673,1.5571559613224766,-0.24221132899251827,0.8428492678399792,0.5487721681964972,0.9886001370636728,-0.16251400074754818,1.5325436558776693,0.8428492678399792,-0.14287070187912912,-0.30320435577832683
3,447
Nuclear envelope ne reassembly
11
50
2.928696
0.003404
Q14739,Q9BTX1,Q9BVA1,P42167,Q9BUF5,Q8NFH4,P68371,P04350,Q13885,Q86Y07,Q86XL3
Processes and pathways
Reactome Pathways
msigdb_reactome
128,96,34,132,107,173,78,47,52,244,246
744,2276,841,2669,47,1006,1066,3118,2023,1264,3322,1820,132,3001,259,2709,1476,1234,1730,78,987,52,128,2677,1082,2096,246,244,906,2610,1638,173,634,1993,892,1995,1024,1749,704,719,1849,96,107,34,3395,1542,1218,1184,1094,2536
0.4006592727447067,-0.36528796300450794,0.3156532797160656,-0.5585258554562905,2.9427278149247016,0.19313737866175912,0.15734332005004562,-0.9070004618348723,-0.2624237136765148,0.04773817048517167,-1.241143026979425,-0.1822683354853108,2.178194878551719,-0.7868309696564781,1.4702992943855286,-0.5806822940457038,-0.04627372815783212,0.06624331600225977,-0.14287070187912912,2.685738533107751,0.21089999179645574,2.890903968218817,2.2196712726732395,-0.5585258554562905,0.15734332005004562,-0.28275422227728697,1.5571559613224766,1.5816085902590042,0.2636616261122957,-0.5146374427323911,-0.10391188008073553,1.9528130358260574,0.5326129525524724,-0.24221132899251827,0.2810765284904778,-0.24221132899251827,0.19313737866175912,-0.14287070187912912,0.45071130368158374,0.4341047300866308,-0.1822683354853108,2.4789875321197483,2.381281697129018,3.200287370541324,-1.5526301524190533,-0.06538144972417397,0.0846519922036011,0.10296527861463395,0.15734332005004562,-0.471302155269236
3,447
Glycosylation
23
45
2.920293
0.003497
Q96L58,O60502,O60568,P04844,Q8TCJ2,Q9BT22,P46977,Q10472,Q2TAA5,O15118,Q9H0U3,O43505,Q16706,Q6UW63,O75352,Q8NAT1,Q9H3H5,P04062,Q6ZXV5,Q86YN1,P04843,Q96JB2,O75503
Processes and pathways
GO Biological process
msigdb_gobp
390,394,642,537,540,168,174,305,184,186,325,577,593,456,210,472,224,97,486,98,607,624,492
2620,186,1710,577,668,394,642,2015,3212,210,492,2242,97,607,537,2635,174,887,1480,1681,1078,2292,1575,305,1684,1930,2143,593,184,456,486,1533,98,472,540,624,390,3206,168,325,224,1027,972,1762,1763
-0.5365115565809986,1.8633490032538682,-0.14287070187912912,0.6126954261187706,0.4836959753352828,0.9742827906130651,0.5163809909451085,-0.2624237136765148,-1.0316061132826644,1.7484867974571487,0.7828838337881776,-0.3444696497798871,2.4693260750464634,0.5648593382990243,0.6755089741541659,-0.5365115565809986,1.9417437419205628,0.2810765284904778,-0.04627372815783212,-0.12333709979746053,0.15734332005004562,-0.36528796300450794,-0.08459375235902318,1.2505830026120932,-0.12333709979746053,-0.2221155959941241,-0.30320435577832683,0.5968202922124238,1.8859120022561358,0.8428492678399792,0.7979678150313219,-0.06538144972417397,2.4693260750464634,0.8279499860422683,0.6755089741541659,0.5487721681964972,0.9886001370636728,-1.0063130127151403,1.9967733661723275,1.1969478078787075,1.6897278697989968,0.19313737866175912,0.2285742779294462,-0.14287070187912912,-0.14287070187912912
3,447
Abnormal biliary tract morphology
11
23
2.918194
0.003521
Q14739,P04062,P07602,Q9Y276,Q5XKP0,P09601,P14174,Q9NSD9,Q10713,Q9NZJ7,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,97,166,461,137,11,330,272,344,187,93
531,2669,97,166,11,330,2892,2330,2451,1340,2132,344,2713,93,128,137,1843,1698,272,187,1320,461,2065
0.6910437992675935,-0.5585258554562905,2.4693260750464634,2.007685211650335,3.804859663855004,1.1698368489882653,-0.6936680218939302,-0.3862322082359554,-0.44983727276622243,0.010434058495094673,-0.30320435577832683,1.1287949380852866,-0.5806822940457038,2.4886252124811126,2.2196712726732395,2.1572887559147627,-0.1822683354853108,-0.12333709979746053,1.40700578874686,1.8633490032538682,0.029135457235295485,0.8428492678399792,-0.2624237136765148
3,447
Autophagy
14
51
2.910722
0.003606
Q8IWA4,Q15388,Q9BVA1,Q9NS69,Q9Y2Q5,Q9BUF5,P68371,P04350,Q7Z3C6,Q8N4H5,Q13885,P54646,O95140,P21796
Processes and pathways
Reactome Pathways
msigdb_reactome
256,353,34,3,462,107,78,47,176,20,52,375,437,27
1711,605,2277,437,1867,464,47,708,1007,784,1193,1775,27,732,1102,375,2369,3120,590,1077,78,1683,753,1928,1013,52,1784,353,559,176,256,20,2155,892,3162,719,1309,2688,1752,2937,107,34,1905,3,1116,1184,462,2536,2115,3245,1187
-0.14287070187912912,0.5648593382990243,-0.36528796300450794,0.8871862971088242,-0.20213507046424417,0.8279499860422683,2.9427278149247016,0.4341047300866308,0.19313737866175912,0.3668988157742944,0.0846519922036011,-0.16251400074754818,3.3503698232892996,0.4174209793635682,0.13930990831158938,1.0312209548801738,-0.40730404219216754,-0.9070004618348723,0.5968202922124238,0.15734332005004562,2.685738533107751,-0.12333709979746053,0.4006592727447067,-0.2221155959941241,0.19313737866175912,2.890903968218817,-0.16251400074754818,1.1011786466586961,0.6442383099094389,1.9306423672509032,1.4953208273418972,3.5912373381541602,-0.30320435577832683,0.2810765284904778,-0.9562907027938861,0.4341047300866308,0.029135457235295485,-0.5585258554562905,-0.14287070187912912,-0.7167208001281143,2.381281697129018,3.200287370541324,-0.20213507046424417,4.276636208213452,0.13930990831158938,0.10296527861463395,0.8428492678399792,-0.471302155269236,-0.28275422227728697,-1.0570912841778808,0.10296527861463395
3,447
Slc mediated transmembrane transport
11
19
2.903064
0.003695
Q8TB61,P05141,P55011,Q70HW3,P35613,P53985,P12235,P12236,Q8NEW0,P30825,Q9UBX3
Processes and pathways
Reactome Pathways
msigdb_reactome
64,258,449,72,266,237,208,183,55,310,31
258,1915,844,208,183,2705,310,266,1473,237,449,1018,1450,72,55,64,1501,31,530
1.4702992943855286,-0.2221155959941241,0.3156532797160656,1.7717381563510717,1.8859120022561358,-0.5806822940457038,1.237246593120908,1.4324515322294316,-0.04627372815783212,1.6179929845170453,0.8576880629169049,0.19313737866175912,-0.027269365976897105,2.722191252729754,2.8559762796306747,2.776248153122407,-0.04627372815783212,3.272073939679055,0.7065124420438686
3,447
Alcohol biosynthetic process
17
38
2.892867
0.003817
Q14739,P04062,Q13510,Q16850,Q15800,Q15392,P37268,O75845,Q9UBM7,O15269,P16435,Q15125,O76062,O94905,P00374,P14324,P54646
Processes and pathways
GO Biological process
msigdb_gobp
128,97,121,164,7,40,199,357,400,239,275,84,115,463,153,402,375
3070,239,628,476,357,115,463,153,1161,97,2812,2246,402,275,2703,1977,199,1978,1621,1475,750,375,1296,3314,1683,121,2375,128,84,2860,40,581,7,2862,164,2688,2475,400
-0.8584195385239018,1.6059037631322783,0.5326129525524724,0.8129896825372822,1.0872927564021313,2.2912039487046916,0.8279499860422683,2.0617845088395463,0.10296527861463395,2.4693260750464634,-0.6480246355463081,-0.3444696497798871,0.9599094643624182,1.3942178014247664,-0.5806822940457038,-0.24221132899251827,1.794848233650915,-0.24221132899251827,-0.10391188008073553,-0.04627372815783212,0.4006592727447067,1.0312209548801738,0.029135457235295485,-1.214219613160026,-0.12333709979746053,2.270900210400071,-0.40730404219216754,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,-0.6707700428550947,2.0294163563584418,-0.5585258554562905,-0.44983727276622243,0.9742827906130651
3,447
Nonalcoholic fatty liver disease
19
55
2.890885
0.003842
O75306,P14406,O43676,Q9UDW1,P21912,O14949,Q99643,O75438,O96000,Q86Y39,O95168,Q9Y6M9,Q9P0J0,P13073,P42574,P51970,P00403,P54646,P20674
Processes and pathways
WikiPathways
msigdb_wp
382,1,8,14,270,24,432,181,568,71,453,86,87,89,229,484,245,375,508
2182,1597,2917,24,8,2272,1327,382,706,181,2117,453,3383,2390,568,245,1774,578,802,879,89,1,1228,922,3336,508,270,981,3345,2495,882,1009,229,1196,619,3214,484,1102,375,1075,1879,1729,1886,1103,1683,2377,3236,3142,1631,71,1698,432,87,14,86
-0.3237756446783554,-0.10391188008073553,-0.7167208001281143,3.411935775289236,3.873674680039861,-0.36528796300450794,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,-0.16251400074754818,0.6126954261187706,0.349898446135214,0.2810765284904778,2.517396848234407,4.313649129144161,0.06624331600225977,0.2461611801381823,-1.2956536049018468,0.7372535957044981,1.40700578874686,0.21089999179645574,-1.3232487120310719,-0.471302155269236,0.2810765284904778,0.19313737866175912,1.6420560339548476,0.0846519922036011,0.5487721681964972,-1.0316061132826644,0.7979678150313219,0.13930990831158938,1.0312209548801738,0.15734332005004562,-0.20213507046424417,-0.14287070187912912,-0.20213507046424417,0.13930990831158938,-0.12333709979746053,-0.40730404219216754,-1.0570912841778808,-0.9315555215226238,-0.10391188008073553,2.7312521573765434,-0.12333709979746053,0.9018467708360485,2.5269406716164067,3.7489696574923244,2.5364613381868493
3,447
Endoplasmic reticulum golgi intermediate compartment membrane
14
26
2.881923
0.003953
P24390,Q13190,Q9Y3A6,O15498,Q9Y3B3,O95070,Q969X5,Q10472,P49755,P51572,Q15363,Q9Y282,O15260,Q8N511
Localization
GO Cellular component
msigdb_gocc
0,322,422,197,234,171,429,305,343,404,222,26,88,63
88,197,1064,171,0,3313,611,343,404,3306,953,752,2292,305,1174,322,222,592,63,429,2001,3105,452,26,422,234
2.517396848234407,1.794848233650915,0.15734332005004562,1.9638504485042398,4.529155521859711,-1.214219613160026,0.5648593382990243,1.1287949380852866,0.9599094643624182,-1.1875123306433095,0.2285742779294462,0.4006592727447067,-0.36528796300450794,1.2505830026120932,0.10296527861463395,1.1969478078787075,1.7015526819939406,0.5968202922124238,2.776248153122407,0.9018467708360485,-0.24221132899251827,-0.8826227148684676,0.8576880629169049,3.396631569290751,0.9309929669262402,1.6300436532822637
3,447
Steroid binding
12
22
2.874716
0.004044
P38435,P35610,P04062,O15118,P30536,O15173,P45880,O94905,O00264,P05023,P21796,Q14108
Functions
GO Molecular function
msigdb_gomf
129,321,97,186,41,42,16,463,151,309,27,93
151,186,42,476,463,97,3074,309,2541,27,1290,2441,41,321,129,16,557,93,971,2348,3350,2003
2.0725136772787915,1.8633490032538682,3.010795820978051,0.8129896825372822,0.8279499860422683,2.4693260750464634,-0.8584195385239018,1.237246593120908,-0.49290160023430213,3.3503698232892996,0.029135457235295485,-0.44983727276622243,3.0360255403392498,1.1969478078787075,2.1989886186203123,3.6994359897329634,0.6442383099094389,2.4886252124811126,0.2285742779294462,-0.3862322082359554,-1.3232487120310719,-0.24221132899251827
3,447
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins
25
62
2.873472
0.00406
O75306,O43676,Q9UDW1,P21912,O75880,P03886,O75964,O14949,P56134,Q99643,O75438,O96000,Q9NPL8,Q86Y39,O95168,P24539,P56385,Q9Y6M9,Q9P0J0,O43819,P13073,P51970,P00403,Q16134,P20674
Processes and pathways
Reactome Pathways
msigdb_reactome
382,8,14,270,520,146,21,24,405,432,181,568,193,71,453,209,337,86,87,340,89,484,245,504,508
2182,1597,24,8,2272,340,1327,382,706,181,2117,520,2748,21,453,3383,2390,568,245,146,1128,1163,578,802,879,89,3230,1228,922,3336,508,270,981,209,2847,3345,2495,1009,1617,3171,2790,1196,3406,3214,484,405,337,2257,504,3142,1631,71,432,910,3061,2875,2656,193,3039,87,14,86
-0.3237756446783554,-0.10391188008073553,3.411935775289236,3.873674680039861,-0.36528796300450794,1.1287949380852866,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,0.7065124420438686,-0.6029828692428588,3.5692505459608204,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,0.10296527861463395,0.6126954261187706,0.349898446135214,0.2810765284904778,2.517396848234407,-1.0570912841778808,0.06624331600225977,0.2461611801381823,-1.2956536049018468,0.7372535957044981,1.40700578874686,0.21089999179645574,1.7601302536193415,-0.6707700428550947,-1.3232487120310719,-0.471302155269236,0.19313737866175912,-0.10391188008073553,-0.9812088834856775,-0.6254296213866243,0.0846519922036011,-1.673164747906431,-1.0316061132826644,0.7979678150313219,0.9599094643624182,1.1425261705350076,-0.3444696497798871,0.75252729309868,-0.9315555215226238,-0.10391188008073553,2.7312521573765434,0.9018467708360485,0.2636616261122957,-0.8343882553406996,-0.6707700428550947,-0.5365115565809986,1.8292524636194953,-0.8105262504581725,2.5269406716164067,3.7489696574923244,2.5364613381868493
3,447
Endoplasmic reticulum to golgi vesicle mediated transport
18
70
2.860932
0.004224
P24390,Q96PC5,Q13190,O95249,Q9P2W9,Q9Y3A6,O43731,O15498,Q9Y3B3,O95070,Q9NR31,Q969X5,Q9HCU5,Q8NHH9,P49755,P51572,Q15363,Q9Y282
Processes and pathways
GO Biological process
msigdb_gobp
0,191,322,66,68,422,6,197,234,171,206,429,441,339,343,404,222,26
1001,780,864,197,2841,1601,6,2624,3212,1064,1913,171,66,2626,865,1127,2125,0,1337,618,611,343,404,846,2498,1521,2453,2369,953,734,2292,1174,322,1733,222,2040,715,1835,1448,962,2607,2216,339,1994,1691,3036,429,624,191,2001,452,2167,441,1029,206,2529,68,2318,3329,777,1661,26,1592,586,422,234,1594,1063,1157,779
0.19313737866175912,0.3668988157742944,0.29840678518812824,1.794848233650915,-0.6707700428550947,-0.10391188008073553,3.9547704783957736,-0.5365115565809986,-1.0316061132826644,0.15734332005004562,-0.2221155959941241,1.9638504485042398,2.7583110565843194,-0.5365115565809986,0.29840678518812824,0.12118423630495645,-0.30320435577832683,4.529155521859711,0.010434058495094673,0.5487721681964972,0.5648593382990243,1.1287949380852866,0.9599094643624182,0.3156532797160656,-0.471302155269236,-0.06538144972417397,-0.44983727276622243,-0.40730404219216754,0.2285742779294462,0.4174209793635682,-0.36528796300450794,0.10296527861463395,1.1969478078787075,-0.14287070187912912,1.7015526819939406,-0.2624237136765148,0.4341047300866308,-0.1822683354853108,-0.027269365976897105,0.2285742779294462,-0.5146374427323911,-0.3237756446783554,1.1425261705350076,-0.24221132899251827,-0.12333709979746053,-0.8105262504581725,0.9018467708360485,0.5487721681964972,1.8292524636194953,-0.24221132899251827,0.8576880629169049,-0.30320435577832683,0.8871862971088242,0.19313737866175912,1.7833107392720506,-0.471302155269236,2.7583110565843194,-0.36528796300450794,-1.241143026979425,0.3838188193188344,-0.10391188008073553,3.396631569290751,-0.08459375235902318,0.6126954261187706,0.9309929669262402,1.6300436532822637,-0.08459375235902318,0.17528547971368946,0.12118423630495645,0.3838188193188344
3,447
Glycerophospholipid biosynthesis
14
28
2.850302
0.004368
P48651,Q53H12,Q8NCC3,Q8NF37,Q9NQZ5,Q9NP80,Q96N66,Q9NPH0,Q99943,Q9HCL2,Q86UL3,Q8IV08,Q8N2A8,O95674
Processes and pathways
Reactome Pathways
msigdb_reactome
161,549,289,264,138,398,232,205,473,506,471,313,152,220
567,1036,220,1775,805,1519,1232,161,1132,1434,1678,1077,549,471,313,152,289,264,232,2799,473,3350,896,506,398,205,138,1658
0.6285012150671874,0.17528547971368946,1.7015526819939406,-0.16251400074754818,0.349898446135214,-0.06538144972417397,0.06624331600225977,2.040236030803411,0.12118423630495645,-0.027269365976897105,-0.12333709979746053,0.15734332005004562,0.6599073521556105,0.8279499860422683,1.237246593120908,2.0725136772787915,1.3296137106483024,1.445109921894803,1.6420560339548476,-0.6254296213866243,0.8279499860422683,-1.3232487120310719,0.2810765284904778,0.75252729309868,0.9742827906130651,1.7833107392720506,2.1572887559147627,-0.10391188008073553
3,447
Ire1alpha activates chaperones
7
25
2.849863
0.004374
O43731,O95070,O14773,Q9Y5M8,Q9NWM8,P43307,O76024
Processes and pathways
Reactome Pathways
msigdb_reactome
6,171,145,50,308,25,189
145,6,189,1913,171,2669,2072,924,25,2707,2080,1076,1078,2038,1104,1527,1241,1454,441,1853,308,897,2577,1594,50
2.1257159606954366,3.9547704783957736,1.840651870597142,-0.2221155959941241,1.9638504485042398,-0.5585258554562905,-0.28275422227728697,0.2461611801381823,3.396631569290751,-0.5806822940457038,-0.28275422227728697,0.15734332005004562,0.15734332005004562,-0.2624237136765148,0.13930990831158938,-0.06538144972417397,0.06624331600225977,-0.027269365976897105,0.8871862971088242,-0.1822683354853108,1.2505830026120932,0.2810765284904778,-0.49290160023430213,-0.08459375235902318,2.9341371514763055
3,447
Transporter activity
95
178
2.844167
0.004453
Q9NS69,O60830,Q8N4V1,P0CG08,Q9Y6M7,O43676,Q99595,Q9UDW1,P45880,Q00169,O75964,O43681,P21796,Q9UBX3,P30536,O15173,Q9NVV0,Q9H2D1,P61916,Q8NEW0,O96000,Q8TB61,Q9H2V7,P08574,Q70HW3,Q9BSK2,Q9Y277,Q9Y6M9,Q9P0J0,P13073,P04062,Q9HD20,O14925,Q7L0J3,P38435,P16615,Q9HC21,P03886,Q9Y487,Q96H78,O95202,Q93050,Q7Z3C6,O75438,P12236,O15118,P17900,P12235,P24539,P98194,L0R6Q1,P53985,Q8WTV0,P00403,Q13423,P05141,O95563,Q9Y5J9,Q9UM00,P28288,O43772,Q8IXU6,Q96NB2,Q07820,P08183,Q6KCM7,P30825,P05023,Q4KMQ2,Q9H0U3,Q9Y619,Q86VD7,P61619,P56385,P49755,O43808,Q15388,Q5T1Q4,Q9BVC6,Q8NE01,O75306,P20020,P56134,Q14728,Q6NUK1,Q96ES6,P51790,Q00325,P55011,O95168,O96008,P51970,P23634,Q99797,P20674
Functions
GO Molecular function
msigdb_gomf
3,4,5,514,530,8,9,14,16,524,21,531,27,31,41,42,563,46,557,55,568,64,69,578,72,76,82,86,87,89,97,102,106,123,129,136,143,146,149,165,169,175,176,181,183,186,198,208,209,215,217,237,241,245,255,258,269,282,285,287,286,295,296,300,299,306,310,309,323,325,329,332,336,337,343,347,353,368,370,379,382,403,405,417,425,431,448,450,449,453,464,484,483,502,508
217,2182,1909,1597,666,106,1003,186,42,8,2272,531,286,347,4,763,1327,382,706,181,2117,1669,2748,21,2277,453,3383,169,2390,269,568,464,245,146,1128,97,309,1969,258,1163,1329,2541,299,1915,578,514,879,844,208,183,89,136,198,3336,403,508,2492,3361,27,1290,483,209,2847,287,3345,41,310,1009,1231,1617,2924,129,2130,788,661,16,1196,3406,1132,343,3214,448,749,484,1197,2709,1233,237,1677,449,405,337,1076,336,557,215,524,450,1779,1389,829,752,300,255,3269,2142,417,353,1018,3142,1631,323,368,306,3434,2762,425,1450,652,72,123,176,332,295,5,1112,379,966,55,1053,64,1143,241,2222,175,431,165,296,971,1903,9,502,2799,1699,76,370,2348,912,3350,325,46,69,2003,1501,636,143,102,2835,3,1117,2737,563,87,31,14,597,1253,1660,285,1183,82,149,282,2743,329,3273,530,86
1.7015526819939406,-0.3237756446783554,-0.2221155959941241,-0.10391188008073553,0.4836959753352828,2.391162989421182,0.19313737866175912,1.8633490032538682,3.010795820978051,3.873674680039861,-0.36528796300450794,0.6910437992675935,1.342624187693322,1.115012567814737,4.1444590074269065,0.3838188193188344,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,-0.12333709979746053,-0.6029828692428588,3.5692505459608204,-0.36528796300450794,0.8428492678399792,-1.4938226351232837,1.9858304188448097,-0.4285051553274654,1.40700578874686,0.6285012150671874,0.8279499860422683,1.5694020954564156,2.1257159606954366,0.12118423630495645,2.4693260750464634,1.237246593120908,-0.24221132899251827,1.4702992943855286,0.10296527861463395,0.010434058495094673,-0.49290160023430213,1.2771132720400578,-0.2221155959941241,0.6126954261187706,0.7219155083838219,0.2810765284904778,0.3156532797160656,1.7717381563510717,1.8859120022561358,2.517396848234407,2.1572887559147627,1.794848233650915,-1.2956536049018468,0.9599094643624182,0.7372535957044981,-0.471302155269236,-1.3791392568827447,3.3503698232892996,0.029135457235295485,0.7979678150313219,1.7601302536193415,-0.6707700428550947,1.342624187693322,-1.3232487120310719,3.0360255403392498,1.237246593120908,0.19313737866175912,0.06624331600225977,-0.10391188008073553,-0.7167208001281143,2.1989886186203123,-0.30320435577832683,0.3668988157742944,0.500075572431892,3.6994359897329634,0.0846519922036011,-1.673164747906431,0.12118423630495645,1.1287949380852866,-1.0316061132826644,0.8576880629169049,0.4006592727447067,0.7979678150313219,0.0846519922036011,-0.5806822940457038,0.06624331600225977,1.6179929845170453,-0.12333709979746053,0.8576880629169049,0.9599094643624182,1.1425261705350076,0.15734332005004562,1.156206673163405,0.6442383099094389,1.7133407362411066,0.7065124420438686,0.8576880629169049,-0.16251400074754818,-0.008367163295788871,0.3328168814905901,0.4006592727447067,1.2771132720400578,1.4953208273418972,-1.1086506296557357,-0.30320435577832683,0.9454796834826562,1.1011786466586961,0.19313737866175912,-0.9315555215226238,-0.10391188008073553,1.1969478078787075,1.059363369451296,1.2505830026120932,-2.5135956035021803,-0.6029828692428588,0.9164488273167519,-0.027269365976897105,0.5163809909451085,2.722191252729754,2.2607083952402736,1.9306423672509032,1.1698368489882653,1.3034558937486695,4.040872839878629,0.13930990831158938,1.0170687594342533,0.2285742779294462,2.8559762796306747,0.17528547971368946,2.776248153122407,0.12118423630495645,1.6059037631322783,-0.3237756446783554,1.9417437419205628,0.9018467708360485,2.018566145549778,1.3034558937486695,0.2285742779294462,-0.20213507046424417,3.8600030048314653,0.7677371814906225,-0.6254296213866243,-0.12333709979746053,2.6948832866620145,1.059363369451296,-0.3862322082359554,0.2636616261122957,-1.3232487120310719,1.1969478078787075,2.9513000228072084,2.749311957797667,-0.24221132899251827,-0.04627372815783212,0.5326129525524724,2.1362689307517044,2.42065765575822,-0.6480246355463081,4.276636208213452,0.13930990831158938,-0.5806822940457038,0.6442383099094389,2.5269406716164067,3.272073939679055,3.7489696574923244,0.5968202922124238,0.06624331600225977,-0.10391188008073553,1.3555894999858193,0.10296527861463395,2.6118073444066714,2.0938827725307765,1.3685099847547963,-0.5806822940457038,1.1834170961274035,-1.1086506296557357,0.7065124420438686,2.5364613381868493
3,447
Carboxylic acid transport
15
38
2.839248
0.004522
P28288,P07602,Q9Y619,Q96NB2,Q9NP80,P14174,P53985,Q7L0J3,Q9H2D1,O60831,O95563,Q15041,P30825,Q9NZJ7,Q9UBX3
Processes and pathways
GO Biological process
msigdb_gobp
287,166,329,296,398,330,237,123,46,235,269,311,310,187,31
666,235,1669,1160,269,2121,3091,166,1915,330,730,287,310,1231,661,1233,237,449,3407,829,1683,311,649,1018,2762,1450,123,1143,296,1699,46,1501,636,398,187,31,1660,329
0.4836959753352828,1.6179929845170453,-0.12333709979746053,0.10296527861463395,1.40700578874686,-0.30320435577832683,-0.8826227148684676,2.007685211650335,-0.2221155959941241,1.1698368489882653,0.4174209793635682,1.342624187693322,1.237246593120908,0.06624331600225977,0.500075572431892,0.06624331600225977,1.6179929845170453,0.8576880629169049,-1.673164747906431,0.3328168814905901,-0.12333709979746053,1.237246593120908,0.5163809909451085,0.19313737866175912,-0.6029828692428588,-0.027269365976897105,2.2607083952402736,0.12118423630495645,1.3034558937486695,-0.12333709979746053,2.9513000228072084,-0.04627372815783212,0.5326129525524724,0.9742827906130651,1.8633490032538682,3.272073939679055,-0.10391188008073553,1.1834170961274035
3,447
Cholesterol metabolism with bloch and kandutschrussell pathways
11
24
2.838067
0.004539
Q14739,P35610,Q14534,Q16850,Q15800,Q15392,P37268,O75845,Q9UBM7,O76062,Q15125
Processes and pathways
WikiPathways
msigdb_wp
128,321,130,164,7,40,199,357,400,115,84
627,1965,357,115,842,402,2814,321,199,1621,619,750,3314,2375,130,128,84,2860,40,581,7,164,1359,400
0.5326129525524724,-0.24221132899251827,1.0872927564021313,2.2912039487046916,0.3156532797160656,0.9599094643624182,-0.6480246355463081,1.1969478078787075,1.794848233650915,-0.10391188008073553,0.5487721681964972,0.4006592727447067,-1.214219613160026,-0.40730404219216754,2.1886057148305667,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,2.0294163563584418,0.010434058495094673,0.9742827906130651
3,447
Primary active transmembrane transporter activity
22
55
2.831919
0.004627
O75306,O43676,P16615,Q9UDW1,P03886,P20020,P28288,P08183,O75438,P05023,O96000,O95168,Q9Y6M9,P98194,Q9P0J0,P13073,Q15388,Q9HD20,P51970,P23634,P00403,P20674
Functions
GO Molecular function
msigdb_gomf
382,8,136,14,146,403,287,299,181,309,568,453,86,215,87,89,353,102,484,483,245,508
2182,1597,8,2272,763,1327,382,706,181,2117,453,3383,2390,568,245,146,1128,309,1969,1163,299,578,879,89,136,3336,403,508,2492,3361,483,287,3345,1009,1231,2924,2130,1196,3214,749,484,1076,215,752,353,3142,1631,102,2835,1117,87,14,1253,2743,86
-0.3237756446783554,-0.10391188008073553,3.873674680039861,-0.36528796300450794,0.3838188193188344,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,1.237246593120908,-0.24221132899251827,0.10296527861463395,1.2771132720400578,0.6126954261187706,0.2810765284904778,2.517396848234407,2.1572887559147627,-1.2956536049018468,0.9599094643624182,0.7372535957044981,-0.471302155269236,-1.3791392568827447,0.7979678150313219,1.342624187693322,-1.3232487120310719,0.19313737866175912,0.06624331600225977,-0.7167208001281143,-0.30320435577832683,0.0846519922036011,-1.0316061132826644,0.4006592727447067,0.7979678150313219,0.15734332005004562,1.7133407362411066,0.4006592727447067,1.1011786466586961,-0.9315555215226238,-0.10391188008073553,2.42065765575822,-0.6480246355463081,0.13930990831158938,2.5269406716164067,3.7489696574923244,0.06624331600225977,-0.5806822940457038,2.5364613381868493
3,447
Cardiac muscle contraction
6
22
2.826844
0.004701
P14406,P16615,Q9UDW1,P00403,O14949,P13073
Processes and pathways
KEGG Pathways
msigdb_kegg
1,136,14,245,24,89
24,245,309,1969,2751,578,2123,802,879,89,1,1228,922,136,508,981,1009,1196,1677,828,1884,14
3.411935775289236,1.5694020954564156,1.237246593120908,-0.24221132899251827,-0.6029828692428588,0.6126954261187706,-0.30320435577832683,0.349898446135214,0.2810765284904778,2.517396848234407,4.313649129144161,0.06624331600225977,0.2461611801381823,2.1572887559147627,0.7372535957044981,0.21089999179645574,0.19313737866175912,0.0846519922036011,-0.12333709979746053,0.3328168814905901,-0.20213507046424417,3.7489696574923244
3,447
Organic hydroxy compound biosynthetic process
19
53
2.816383
0.004857
Q14739,Q14534,Q15800,Q9UBM7,P16435,P00374,P14324,P28288,Q16850,Q15392,P37268,Q15125,O94905,P04062,O75845,O15269,O76062,P54646,Q13510
Processes and pathways
GO Biological process
msigdb_gobp
128,130,7,400,275,153,402,287,164,40,199,84,463,97,357,239,115,375,121
3070,1003,239,628,476,357,115,463,153,1161,97,2972,2812,2246,402,275,2703,1290,2441,287,1336,1977,199,1978,1621,1475,750,375,1296,3314,1683,121,2375,130,128,84,2860,40,581,7,2862,164,3376,1057,971,2688,2962,2003,2475,400,1505,3417,2970
-0.8584195385239018,0.19313737866175912,1.6059037631322783,0.5326129525524724,0.8129896825372822,1.0872927564021313,2.2912039487046916,0.8279499860422683,2.0617845088395463,0.10296527861463395,2.4693260750464634,-0.7632999174742385,-0.6480246355463081,-0.3444696497798871,0.9599094643624182,1.3942178014247664,-0.5806822940457038,0.029135457235295485,-0.44983727276622243,1.342624187693322,0.010434058495094673,-0.24221132899251827,1.794848233650915,-0.24221132899251827,-0.10391188008073553,-0.04627372815783212,0.4006592727447067,1.0312209548801738,0.029135457235295485,-1.214219613160026,-0.12333709979746053,2.270900210400071,-0.40730404219216754,2.1886057148305667,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,-0.6707700428550947,2.0294163563584418,-1.4359917276919325,0.17528547971368946,0.2285742779294462,-0.5585258554562905,-0.7399306553991354,-0.24221132899251827,-0.44983727276622243,0.9742827906130651,-0.04627372815783212,-1.8292815969845304,-0.7399306553991354
3,447
Mitochondrial protein import
15
33
2.812087
0.004922
Q15388,Q9NS69,O60830,Q9Y276,Q99595,O14925,Q9Y512,P12235,Q13505,Q8N4H5,Q10713,P12236,Q9Y5J9,P21796,O75431
Processes and pathways
Reactome Pathways
msigdb_reactome
353,3,4,461,9,106,274,208,407,20,344,183,282,27,413
106,543,4,3343,413,2971,1669,2277,464,1163,578,3248,208,183,27,2847,3119,344,407,353,737,1742,20,2103,9,3037,1028,3,1364,1660,461,274,282
2.391162989421182,0.6599073521556105,4.1444590074269065,-1.3232487120310719,0.9454796834826562,-0.7632999174742385,-0.12333709979746053,-0.36528796300450794,0.8279499860422683,0.10296527861463395,0.6126954261187706,-1.0827717031939503,1.7717381563510717,1.8859120022561358,3.3503698232892996,-0.6707700428550947,-0.9070004618348723,1.1287949380852866,0.9599094643624182,1.1011786466586961,0.4174209793635682,-0.14287070187912912,3.5912373381541602,-0.28275422227728697,3.8600030048314653,-0.8105262504581725,0.19313737866175912,4.276636208213452,0.010434058495094673,-0.10391188008073553,0.8428492678399792,1.40700578874686,1.3685099847547963
3,447
Inner mitochondrial membrane organization
14
19
2.785744
0.005341
Q9H3K2,Q53H12,Q9NVH1,O95202,Q5XKP0,Q8WWC4,Q9Y512,Q13505,Q9BUR5,O60313,Q6UXV4,Q9P0J0,Q9Y5J9,O75431
Processes and pathways
GO Biological process
msigdb_gobp
225,549,489,169,137,363,274,407,147,365,213,87,282,413
365,413,2277,169,3119,407,558,549,137,213,363,147,225,489,1364,87,2180,274,282
1.059363369451296,0.9454796834826562,-0.36528796300450794,1.9858304188448097,-0.9070004618348723,0.9599094643624182,0.6442383099094389,0.6599073521556105,2.1572887559147627,1.7250922784124725,1.0733544735925842,2.1045230542075872,1.6659669752722266,0.7979678150313219,0.010434058495094673,2.5269406716164067,-0.30320435577832683,1.40700578874686,1.3685099847547963
3,447
Carbohydrate derivative transport
12
18
2.780388
0.005429
Q8TB61,P05141,P07602,Q86VD7,Q9NZJ7,Q9HC21,P12235,Q8WTV0,Q6KCM7,P12236,O43808,L0R6Q1
Processes and pathways
GO Biological process
msigdb_gobp
64,258,166,332,187,143,208,241,306,183,347,217
217,347,258,166,208,183,661,557,889,306,2762,425,332,64,1143,241,143,187
1.7015526819939406,1.115012567814737,1.4702992943855286,2.007685211650335,1.7717381563510717,1.8859120022561358,0.500075572431892,0.6442383099094389,0.2810765284904778,1.2505830026120932,-0.6029828692428588,0.9164488273167519,1.1698368489882653,2.776248153122407,0.12118423630495645,1.6059037631322783,2.1362689307517044,1.8633490032538682
3,447
Phospholipid metabolism
19
48
2.75814
0.005813
Q8NF37,Q9NQZ5,Q9NP80,Q8N2A8,P48651,Q53H12,Q8NCC3,Q8N9F7,Q8IV08,O15228,P20339,Q9NPH0,Q99943,Q86UL3,Q10713,O95674,Q96N66,Q9NTJ5,Q9HCL2
Processes and pathways
Reactome Pathways
msigdb_reactome
264,138,398,152,161,549,289,440,313,567,579,205,473,471,344,220,232,371,506
1189,567,1036,220,1775,579,805,1519,1567,1232,161,1132,1434,1678,1169,1077,791,1173,344,1394,1929,549,471,313,813,152,440,289,2155,264,2611,232,2654,1245,1752,2799,473,817,3350,896,506,398,205,138,371,637,1658,2532
0.0846519922036011,0.6285012150671874,0.17528547971368946,1.7015526819939406,-0.16251400074754818,0.6126954261187706,0.349898446135214,-0.06538144972417397,-0.08459375235902318,0.06624331600225977,2.040236030803411,0.12118423630495645,-0.027269365976897105,-0.12333709979746053,0.10296527861463395,0.15734332005004562,0.3668988157742944,0.10296527861463395,1.1287949380852866,-0.008367163295788871,-0.2221155959941241,0.6599073521556105,0.8279499860422683,1.237246593120908,0.349898446135214,2.0725136772787915,0.8871862971088242,1.3296137106483024,-0.30320435577832683,1.445109921894803,-0.5146374427323911,1.6420560339548476,-0.5365115565809986,0.06624331600225977,-0.14287070187912912,-0.6254296213866243,0.8279499860422683,0.349898446135214,-1.3232487120310719,0.2810765284904778,0.75252729309868,0.9742827906130651,1.7833107392720506,2.1572887559147627,1.059363369451296,0.5326129525524724,-0.10391188008073553,-0.471302155269236
3,447
Tetrapyrrole binding
8
16
2.737676
0.006188
O43169,Q16850,Q9H7Z7,P09601,P30519,O15173,Q6UW02,O00264
Functions
GO Molecular function
msigdb_gomf
2,164,202,11,12,42,116,151
151,2184,42,2,578,11,746,12,297,164,116,1794,432,1058,202,1458
2.0725136772787915,-0.3237756446783554,3.010795820978051,4.307502880587425,0.6126954261187706,3.804859663855004,0.4006592727447067,3.770017295970376,1.290307859614052,2.0294163563584418,2.2912039487046916,-0.16251400074754818,0.9018467708360485,0.17528547971368946,1.794848233650915,-0.027269365976897105
3,447
Metabolism of steroids
15
46
2.731809
0.006299
Q14739,P38435,Q14534,P04062,Q16850,Q15800,Q15392,P30536,P37268,Q9UBM7,O75845,O76062,Q53GQ0,Q15125,Q8NBQ5
Processes and pathways
Reactome Pathways
msigdb_reactome
128,129,130,97,164,7,40,41,199,400,357,115,148,84,373
3246,627,1003,357,115,865,1127,97,402,1718,1290,2441,2846,41,199,129,1621,619,1340,750,2453,1234,3314,3397,2375,130,128,2677,84,2860,40,2040,2263,581,7,164,148,964,1637,373,971,1359,3356,2003,506,400
-1.0827717031939503,0.5326129525524724,0.19313737866175912,1.0872927564021313,2.2912039487046916,0.29840678518812824,0.12118423630495645,2.4693260750464634,0.9599094643624182,-0.14287070187912912,0.029135457235295485,-0.44983727276622243,-0.6707700428550947,3.0360255403392498,1.794848233650915,2.1989886186203123,-0.10391188008073553,0.5487721681964972,0.010434058495094673,0.4006592727447067,-0.44983727276622243,0.06624331600225977,-1.214219613160026,-1.5823993310130011,-0.40730404219216754,2.1886057148305667,2.2196712726732395,-0.5585258554562905,2.555433683915995,-0.6707700428550947,3.0610973203490204,-0.2624237136765148,-0.3444696497798871,0.6126954261187706,3.9211731425024707,2.0294163563584418,2.0938827725307765,0.2285742779294462,-0.10391188008073553,1.045319009782404,0.2285742779294462,0.010434058495094673,-1.35107584448545,-0.24221132899251827,0.75252729309868,0.9742827906130651
3,447
Schizophrenia
6
23
2.727554
0.006381
P04062,P07602,P16615,P21964,Q9BQE5,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
97,166,136,83,22,187
3041,2012,531,1865,189,1867,97,166,136,83,2453,2254,2404,2043,2798,2048,815,1057,22,2268,2165,2111,187
-0.8343882553406996,-0.2624237136765148,0.6910437992675935,-0.20213507046424417,1.840651870597142,-0.20213507046424417,2.4693260750464634,2.007685211650335,2.1572887559147627,2.574314841840362,-0.44983727276622243,-0.3444696497798871,-0.4285051553274654,-0.2624237136765148,-0.6254296213866243,-0.2624237136765148,0.349898446135214,0.17528547971368946,3.4575058283936557,-0.3444696497798871,-0.30320435577832683,-0.28275422227728697,1.8633490032538682
3,447
Nucleobase containing compound transmembrane transporter activity
11
14
2.727492
0.006382
Q8TB61,P05141,Q86VD7,Q9BSK2,Q9H2D1,Q9HC21,P12235,Q6KCM7,P12236,O43808,L0R6Q1
Functions
GO Molecular function
msigdb_gomf
64,258,332,76,46,143,208,306,183,347,217
217,347,258,208,183,661,1197,306,425,332,64,76,46,143
1.7015526819939406,1.115012567814737,1.4702992943855286,1.7717381563510717,1.8859120022561358,0.500075572431892,0.0846519922036011,1.2505830026120932,0.9164488273167519,1.1698368489882653,2.776248153122407,2.6948832866620145,2.9513000228072084,2.1362689307517044
3,447
Glycosyltransferase
15
34
2.72579
0.006415
Q9H3H5,P04062,Q96L58,Q9BT22,O43505,Q13126,P43490,Q6UW63,P46977,O60568,Q10472,Q8NAT1,Q2TAA5,Q16880,Q8TCJ2
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
224,97,390,168,577,170,105,456,174,642,305,472,184,122,540
1710,577,642,2015,1379,2437,97,1260,1670,1289,2440,2020,1098,681,105,174,2290,2372,1575,305,170,122,184,456,1533,472,2416,540,390,168,224,1027,1762,2739
-0.14287070187912912,0.6126954261187706,0.5163809909451085,-0.2624237136765148,-0.008367163295788871,-0.44983727276622243,2.4693260750464634,0.04773817048517167,-0.12333709979746053,0.029135457235295485,-0.44983727276622243,-0.2624237136765148,0.13930990831158938,0.46724146702283265,2.401019322981899,1.9417437419205628,-0.36528796300450794,-0.40730404219216754,-0.08459375235902318,1.2505830026120932,1.9748561775908344,2.270900210400071,1.8859120022561358,0.8428492678399792,-0.06538144972417397,0.8279499860422683,-0.4285051553274654,0.6755089741541659,0.9886001370636728,1.9967733661723275,1.6897278697989968,0.19313737866175912,-0.14287070187912912,-0.5806822940457038
3,447
Nadh dehydrogenase complex assembly
12
26
2.715982
0.006608
O75306,Q9Y276,O43676,Q86Y39,Q9H061,O95168,P03886,Q96CU9,O75438,Q15070,Q9Y6M9,Q9P0J0
Processes and pathways
GO Biological process
msigdb_gobp
382,461,8,71,13,453,146,180,181,53,86,87
2182,8,2272,1327,382,181,2117,453,2390,568,146,1128,3345,484,53,3142,1631,71,180,2875,13,2656,3039,87,461,86
-0.3237756446783554,3.873674680039861,-0.36528796300450794,0.010434058495094673,1.0028619724328278,1.9083425678170867,-0.30320435577832683,0.8428492678399792,-0.4285051553274654,0.6285012150671874,2.1257159606954366,0.12118423630495645,-1.3232487120310719,0.7979678150313219,2.8647369895860946,-0.9315555215226238,-0.10391188008073553,2.7312521573765434,1.9195087103543416,-0.6707700428550947,3.7489696574923244,-0.5365115565809986,-0.8105262504581725,2.5269406716164067,0.8428492678399792,2.5364613381868493
3,447
Biliary tract abnormality
10
26
2.704694
0.006837
Q14739,P04062,P07602,O95202,Q5XKP0,P09601,P14174,Q9NSD9,Q9NZJ7,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,97,166,169,137,11,330,272,187,93
531,169,3352,2669,97,166,11,330,2892,2330,2451,1340,2132,344,2713,2641,93,128,137,1843,1698,272,187,1320,461,2065
0.6910437992675935,1.9858304188448097,-1.35107584448545,-0.5585258554562905,2.4693260750464634,2.007685211650335,3.804859663855004,1.1698368489882653,-0.6936680218939302,-0.3862322082359554,-0.44983727276622243,0.010434058495094673,-0.30320435577832683,1.1287949380852866,-0.5806822940457038,-0.5365115565809986,2.4886252124811126,2.2196712726732395,2.1572887559147627,-0.1822683354853108,-0.12333709979746053,1.40700578874686,1.8633490032538682,0.029135457235295485,0.8428492678399792,-0.2624237136765148
3,447
Regulation of mitochondrion organization
12
45
2.69272
0.007087
Q9H3K2,P05141,Q9Y6C9,P30536,Q9NX47,Q96A26,Q9H4A6,P12235,Q9H300,Q8N2A8,P21796,P27544
Processes and pathways
GO Biological process
msigdb_gobp
225,258,37,41,301,45,251,208,307,152,27,61
588,1372,2538,365,695,2669,2391,2843,258,1558,3372,208,1775,27,61,1291,2590,41,1976,1978,2198,2451,2956,2603,583,2153,2378,2683,152,966,45,1309,1057,2688,1147,307,225,251,862,1656,301,1658,1414,1768,37
0.5968202922124238,-0.008367163295788871,-0.49290160023430213,1.059363369451296,0.45071130368158374,-0.5585258554562905,-0.4285051553274654,-0.6707700428550947,1.4702992943855286,-0.08459375235902318,-1.4359917276919325,1.7717381563510717,-0.16251400074754818,3.3503698232892996,2.7851863493439573,0.029135457235295485,-0.5146374427323911,3.0360255403392498,-0.24221132899251827,-0.24221132899251827,-0.3237756446783554,-0.44983727276622243,-0.7399306553991354,-0.5146374427323911,0.6126954261187706,-0.30320435577832683,-0.40730404219216754,-0.5585258554562905,2.0725136772787915,0.2285742779294462,2.9598538605341833,0.029135457235295485,0.17528547971368946,-0.5585258554562905,0.12118423630495645,1.2505830026120932,1.6659669752722266,1.5325436558776693,0.3156532797160656,-0.10391188008073553,1.2771132720400578,-0.10391188008073553,-0.008367163295788871,-0.14287070187912912,3.1760717839026786
3,447
Mitochondrial carrier protein [IPR002067]
8
14
2.69186
0.007105
P05141,Q96H78,Q86VD7,Q9HC21,P12235,Q6KCM7,P12236,O43808
Sequence
InterPro Family
interpro_family
258,165,332,143,208,306,183,347
347,1669,258,208,183,1233,306,425,332,165,1699,1501,143,1660
1.115012567814737,-0.12333709979746053,1.4702992943855286,1.7717381563510717,1.8859120022561358,0.06624331600225977,1.2505830026120932,0.9164488273167519,1.1698368489882653,2.018566145549778,-0.12333709979746053,-0.04627372815783212,2.1362689307517044,-0.10391188008073553
3,447
Protein localization to endoplasmic reticulum
15
36
2.688796
0.007171
P24390,Q15629,Q9NQC3,P51572,O43731,P61026,Q99442,P61619,Q9UNL2,Q9Y5M8,P46379,Q13438,O43681,O15258,Q15005
Processes and pathways
GO Biological process
msigdb_gobp
0,33,35,404,6,580,360,336,434,50,179,500,531,219,349
864,219,531,6,2387,2118,2072,1556,2788,0,2128,179,1167,404,3391,3120,1880,1922,580,336,500,349,649,33,1835,1348,1691,970,360,837,35,2529,597,1318,434,50
0.29840678518812824,1.7015526819939406,0.6910437992675935,3.9547704783957736,-0.4285051553274654,-0.30320435577832683,-0.28275422227728697,-0.08459375235902318,-0.6254296213866243,4.529155521859711,-0.30320435577832683,1.9195087103543416,0.10296527861463395,0.9599094643624182,-1.5231044801746638,-0.9070004618348723,-0.20213507046424417,-0.2221155959941241,0.6126954261187706,1.156206673163405,0.7677371814906225,1.115012567814737,0.5163809909451085,3.216350650152123,-0.1822683354853108,0.010434058495094673,-0.12333709979746053,0.2285742779294462,1.0872927564021313,0.3328168814905901,3.1922316667835537,-0.471302155269236,0.5968202922124238,0.029135457235295485,0.9018467708360485,2.9341371514763055
3,447
glycosyltransferase
12
21
2.688612
0.007175
Q9H3H5,Q96L58,Q9H0U3,Q9BT22,Q9P2E5,P46977,Q8NBN7,Q10472,Q8NAT1,P04844,Q6UX07,Q8TCJ2
Functions
Panther Protein class
panther_protein_class
224,390,325,168,460,174,112,305,472,537,250,540
2015,2437,607,537,1260,2020,2635,174,887,1575,305,250,472,112,540,390,168,325,224,1762,460
-0.2624237136765148,-0.44983727276622243,0.5648593382990243,0.6755089741541659,0.04773817048517167,-0.2624237136765148,-0.5365115565809986,1.9417437419205628,0.2810765284904778,-0.08459375235902318,1.2505830026120932,1.5448699088190703,0.8279499860422683,2.3214620624481643,0.6755089741541659,0.9886001370636728,1.9967733661723275,1.1969478078787075,1.6897278697989968,-0.14287070187912912,0.8428492678399792
3,447
Golgi to er retrograde transport
14
74
2.685002
0.007253
P24390,Q9BVA1,Q9P2W9,O43731,Q9Y3B3,Q9BUF5,P68371,P04350,Q10472,Q13885,Q12981,P49755,O15260,Q15363
Processes and pathways
Reactome Pathways
msigdb_reactome
0,34,68,6,234,107,78,47,305,52,439,343,88,222
1769,780,88,1711,2841,6,1064,745,1420,2120,47,2125,0,1616,1337,534,2791,3153,1725,618,343,2670,1198,2498,1521,2030,1477,711,734,590,78,2402,888,1680,2085,1575,305,3157,439,1013,1831,52,1104,1784,1015,649,1138,222,1448,1241,1142,1691,770,3162,2936,3060,107,34,2001,1755,1456,2380,452,837,1853,1088,2058,68,2318,1320,234,1593,1157,1187
-0.16251400074754818,0.3668988157742944,2.517396848234407,-0.14287070187912912,-0.6707700428550947,3.9547704783957736,0.15734332005004562,0.4006592727447067,-0.027269365976897105,-0.30320435577832683,2.9427278149247016,-0.30320435577832683,4.529155521859711,-0.10391188008073553,0.010434058495094673,0.6910437992675935,-0.6254296213866243,-0.9562907027938861,-0.14287070187912912,0.5487721681964972,1.1287949380852866,-0.5585258554562905,0.0846519922036011,-0.471302155269236,-0.06538144972417397,-0.2624237136765148,-0.04627372815783212,0.4341047300866308,0.4174209793635682,0.5968202922124238,2.685738533107751,-0.4285051553274654,0.2810765284904778,-0.12333709979746053,-0.28275422227728697,-0.08459375235902318,1.2505830026120932,-0.9562907027938861,0.8871862971088242,0.19313737866175912,-0.1822683354853108,2.890903968218817,0.13930990831158938,-0.16251400074754818,0.19313737866175912,0.5163809909451085,0.12118423630495645,1.7015526819939406,-0.027269365976897105,0.06624331600225977,0.12118423630495645,-0.12333709979746053,0.3838188193188344,-0.9562907027938861,-0.7167208001281143,-0.8343882553406996,2.381281697129018,3.200287370541324,-0.24221132899251827,-0.14287070187912912,-0.027269365976897105,-0.40730404219216754,0.8576880629169049,0.3328168814905901,-0.1822683354853108,0.15734332005004562,-0.2624237136765148,2.7583110565843194,-0.36528796300450794,0.029135457235295485,1.6300436532822637,-0.08459375235902318,0.12118423630495645,0.10296527861463395
3,447
Steroid metabolic process
28
72
2.677018
0.007428
Q14739,P38435,Q14534,Q15800,Q9UBM7,P16435,Q53GQ0,Q9BQE5,P14324,P28288,Q16850,Q15392,P30536,O15118,P05023,P35610,O95470,P37268,Q15125,O94905,P04062,O75845,Q06520,Q8WTV0,O76062,Q8NBQ5,P54646,Q13510
Processes and pathways
GO Biological process
msigdb_gobp
128,129,130,7,400,275,148,22,402,287,164,40,41,186,309,321,65,199,84,463,97,357,238,241,115,373,375,121
1003,186,476,357,115,463,65,1161,3435,97,309,1970,3384,2246,402,1718,275,1290,2441,2846,2633,287,41,321,199,129,3442,1978,1621,2707,3080,1340,1475,750,375,557,3006,3314,2291,238,1683,121,2375,130,128,1932,84,2860,40,2721,2263,581,7,164,148,559,1637,373,241,2649,3376,971,2962,22,2735,1500,2003,400,2775,1908,1505,1366
0.19313737866175912,1.8633490032538682,0.8129896825372822,1.0872927564021313,2.2912039487046916,0.8279499860422683,2.767289755156624,0.10296527861463395,-2.89120220745136,2.4693260750464634,1.237246593120908,-0.24221132899251827,-1.4938226351232837,-0.3444696497798871,0.9599094643624182,-0.14287070187912912,1.3942178014247664,0.029135457235295485,-0.44983727276622243,-0.6707700428550947,-0.5365115565809986,1.342624187693322,3.0360255403392498,1.1969478078787075,1.794848233650915,2.1989886186203123,-7.315944471895409,-0.24221132899251827,-0.10391188008073553,-0.5806822940457038,-0.8584195385239018,0.010434058495094673,-0.04627372815783212,0.4006592727447067,1.0312209548801738,0.6442383099094389,-0.7868309696564781,-1.214219613160026,-0.36528796300450794,1.6179929845170453,-0.12333709979746053,2.270900210400071,-0.40730404219216754,2.1886057148305667,2.2196712726732395,-0.2221155959941241,2.555433683915995,-0.6707700428550947,3.0610973203490204,-0.5806822940457038,-0.3444696497798871,0.6126954261187706,3.9211731425024707,2.0294163563584418,2.0938827725307765,0.6442383099094389,-0.10391188008073553,1.045319009782404,1.6059037631322783,-0.5365115565809986,-1.4359917276919325,0.2285742779294462,-0.7399306553991354,3.4575058283936557,-0.5806822940457038,-0.04627372815783212,-0.24221132899251827,0.9742827906130651,-0.6029828692428588,-0.20213507046424417,-0.04627372815783212,0.010434058495094673
3,447
Proton transmembrane transporter activity
16
34
2.6726
0.007527
P51790,Q00325,P05141,O95202,Q9UDW1,Q93050,Q96ES6,P12235,P24539,P56385,O75964,Q9Y487,P00403,P13073,P56134,Q13423
Functions
GO Molecular function
msigdb_gomf
448,450,258,169,14,175,431,208,209,337,21,149,245,89,405,255
2748,21,169,245,258,1163,578,879,208,89,508,2492,3361,209,2847,1009,1617,2924,2130,1196,3406,448,405,337,1076,450,255,175,431,1501,14,1253,149,2743
-0.6029828692428588,3.5692505459608204,1.9858304188448097,1.5694020954564156,1.4702992943855286,0.10296527861463395,0.6126954261187706,0.2810765284904778,1.7717381563510717,2.517396848234407,0.7372535957044981,-0.471302155269236,-1.3791392568827447,1.7601302536193415,-0.6707700428550947,0.19313737866175912,-0.10391188008073553,-0.7167208001281143,-0.30320435577832683,0.0846519922036011,-1.673164747906431,0.8576880629169049,0.9599094643624182,1.1425261705350076,0.15734332005004562,0.8576880629169049,1.4953208273418972,1.9417437419205628,0.9018467708360485,-0.04627372815783212,3.7489696574923244,0.06624331600225977,2.0938827725307765,-0.5806822940457038
3,447
Cellular monovalent inorganic cation homeostasis
11
25
2.666619
0.007662
P51790,Q92544,P55011,P0CG08,Q9Y6M7,P50897,Q93050,O75503,Q9Y487,P05023,Q8N511
Processes and pathways
GO Biological process
msigdb_gobp
448,223,449,514,530,77,175,492,149,309,63
492,309,1969,1163,514,949,1517,77,1168,448,828,449,1076,2457,592,63,223,175,1213,2109,1763,1253,149,3273,530
0.7828838337881776,1.237246593120908,-0.24221132899251827,0.10296527861463395,0.7219155083838219,0.2285742779294462,-0.06538144972417397,2.685738533107751,0.10296527861463395,0.8576880629169049,0.3328168814905901,0.8576880629169049,0.15734332005004562,-0.44983727276622243,0.5968202922124238,2.776248153122407,1.6897278697989968,1.9417437419205628,0.0846519922036011,-0.28275422227728697,-0.14287070187912912,0.06624331600225977,2.0938827725307765,-1.1086506296557357,0.7065124420438686
3,447
Secondary active transmembrane transporter activity
10
20
2.664395
0.007713
P51790,Q00325,P05141,P55011,O95202,P53985,Q96ES6,P12235,P12236,Q9UBX3
Functions
GO Molecular function
msigdb_gomf
448,450,258,449,169,237,431,208,183,31
169,258,1915,208,183,661,448,749,1233,237,449,450,829,1018,966,431,912,1501,31,530
1.9858304188448097,1.4702992943855286,-0.2221155959941241,1.7717381563510717,1.8859120022561358,0.500075572431892,0.8576880629169049,0.4006592727447067,0.06624331600225977,1.6179929845170453,0.8576880629169049,0.8576880629169049,0.3328168814905901,0.19313737866175912,0.2285742779294462,0.9018467708360485,0.2636616261122957,-0.04627372815783212,3.272073939679055,0.7065124420438686
3,447
Protein transmembrane transport
13
25
2.664169
0.007718
Q15629,Q15388,Q9NS69,O60830,Q99442,O43615,Q99595,Q07820,O14925,O75381,P61619,P49755,O96008
Processes and pathways
GO Biological process
msigdb_gobp
33,353,3,4,360,543,9,300,106,491,336,343,464
106,543,4,491,2277,824,464,3248,1330,882,343,3391,1922,336,300,353,33,737,2824,2103,360,9,1028,3,597
2.391162989421182,0.6599073521556105,4.1444590074269065,0.7828838337881776,-0.36528796300450794,0.3328168814905901,0.8279499860422683,-1.0827717031939503,0.010434058495094673,0.2810765284904778,1.1287949380852866,-1.5231044801746638,-0.2221155959941241,1.156206673163405,1.2771132720400578,1.1011786466586961,3.216350650152123,0.4174209793635682,-0.6480246355463081,-0.28275422227728697,1.0872927564021313,3.8600030048314653,0.19313737866175912,4.276636208213452,0.5968202922124238
3,447
Sphingolipid metabolism
8
10
2.66368
0.007729
O95470,P04062,P17900,P07602,Q06136,Q13510,Q16880,Q9NZ01
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
65,97,198,166,200,121,122,127
239,628,65,97,166,198,200,121,122,127
1.6059037631322783,0.5326129525524724,2.767289755156624,2.4693260750464634,2.007685211650335,1.794848233650915,1.794848233650915,2.270900210400071,2.270900210400071,2.229971341354025
3,447
Golgi stack
15
34
2.661325
0.007783
Q9UNZ2,O95249,O00461,P0CG08,Q96L58,Q9P2E5,Q8WVQ1,Q16706,Q10472,Q10713,Q8TBA6,P98194,P51572,Q15363,Q9H4A6
Localization
GO Cellular component
msigdb_gocc
290,66,36,514,390,460,457,593,305,344,247,215,404,222,251
36,2624,66,1162,514,2791,404,1169,215,791,3217,2292,1575,305,344,2143,1526,1832,222,593,1349,247,1994,457,624,390,1797,1849,251,460,1764,290,1592,2177
3.184159827888789,-0.5365115565809986,2.7583110565843194,0.10296527861463395,0.7219155083838219,-0.6254296213866243,0.9599094643624182,0.10296527861463395,1.7133407362411066,0.3668988157742944,-1.0316061132826644,-0.36528796300450794,-0.08459375235902318,1.2505830026120932,1.1287949380852866,-0.30320435577832683,-0.06538144972417397,-0.1822683354853108,1.7015526819939406,0.5968202922124238,0.010434058495094673,1.5571559613224766,-0.24221132899251827,0.8428492678399792,0.5487721681964972,0.9886001370636728,-0.16251400074754818,-0.1822683354853108,1.5325436558776693,0.8428492678399792,-0.14287070187912912,1.3296137106483024,-0.08459375235902318,-0.30320435577832683
3,447
Receptor
13
48
2.6612
0.007786
Q14739,P24390,Q9NS69,O43731,P35613,O15173,Q99623,Q99720,Q8WTV0,Q9Y5M8,O00264,O15118,Q14108
Functions
Protein Atlas Molecular function
protein_atlas_molecular_function
128,0,3,6,266,42,271,142,241,50,151,186,93
151,2011,2781,186,42,6,3047,3435,2391,3074,3091,1006,2072,764,1468,1065,544,3117,2021,709,0,845,2494,310,266,478,2979,3362,1482,93,2142,128,1346,1018,2821,241,2222,1797,271,142,3,1460,1657,1120,975,2968,50,3109
2.0725136772787915,-0.2624237136765148,-0.6254296213866243,1.8633490032538682,3.010795820978051,3.9547704783957736,-0.8343882553406996,-2.89120220745136,-0.4285051553274654,-0.8584195385239018,-0.8826227148684676,0.19313737866175912,-0.28275422227728697,0.3838188193188344,-0.04627372815783212,0.15734332005004562,0.6599073521556105,-0.9070004618348723,-0.2624237136765148,0.4341047300866308,4.529155521859711,0.3156532797160656,-0.471302155269236,1.237246593120908,1.4324515322294316,0.8129896825372822,-0.7632999174742385,-1.3791392568827447,-0.04627372815783212,2.4886252124811126,-0.30320435577832683,2.2196712726732395,0.010434058495094673,0.19313737866175912,-0.6480246355463081,1.6059037631322783,-0.3237756446783554,-0.16251400074754818,1.40700578874686,2.1362689307517044,4.276636208213452,-0.027269365976897105,-0.10391188008073553,0.13930990831158938,0.2285742779294462,-0.7399306553991354,2.9341371514763055,-0.8826227148684676
3,447
Cilium assembly
20
65
2.661074
0.007789
A0AVF1,P43034,Q9BVA1,O94927,P07437,P04350,A6NIH7,Q13885,P49368,P17987,P68371,Q8NCM8,O43924,Q15051,Q10713,P78371,Q15019,O43805,P41208,Q9BUF5
Processes and pathways
Reactome Pathways
msigdb_reactome
386,534,34,421,43,47,304,52,571,570,78,594,80,338,344,466,467,475,104,107
386,304,2809,475,80,2623,3185,745,421,3046,47,1006,43,708,2368,3021,570,2125,1264,2250,104,534,1569,571,2079,983,1921,2898,1477,1012,1824,590,78,466,344,1013,1831,52,2258,1104,1784,467,338,1485,1347,1208,2215,2217,1111,594,1746,1691,770,1749,3162,772,107,34,2521,759,1362,1217,3405,821,1593
0.9886001370636728,1.2505830026120932,-0.6480246355463081,0.8129896825372822,2.676572554703228,-0.5365115565809986,-1.0063130127151403,0.4006592727447067,0.9309929669262402,-0.8343882553406996,2.9427278149247016,0.19313737866175912,3.002350444101246,0.4341047300866308,-0.40730404219216754,-0.8105262504581725,0.6285012150671874,-0.30320435577832683,0.04773817048517167,-0.3444696497798871,2.401019322981899,0.6910437992675935,-0.08459375235902318,0.6285012150671874,-0.28275422227728697,0.21089999179645574,-0.2221155959941241,-0.6936680218939302,-0.04627372815783212,0.19313737866175912,-0.1822683354853108,0.5968202922124238,2.685738533107751,0.8279499860422683,1.1287949380852866,0.19313737866175912,-0.1822683354853108,2.890903968218817,-0.3444696497798871,0.13930990831158938,-0.16251400074754818,0.8279499860422683,1.1425261705350076,-0.04627372815783212,0.010434058495094673,0.0846519922036011,-0.3237756446783554,-0.3237756446783554,0.13930990831158938,0.5968202922124238,-0.14287070187912912,-0.12333709979746053,0.3838188193188344,-0.14287070187912912,-0.9562907027938861,0.3838188193188344,2.381281697129018,3.200287370541324,-0.471302155269236,0.4006592727447067,0.010434058495094673,0.0846519922036011,-1.6426669410940329,0.349898446135214,-0.08459375235902318
3,447
Nuclear inner membrane
10
23
2.646105
0.008142
Q14739,Q14728,P50402,Q8IXM6,O94901,Q99720,O76062,Q9H1E5,Q5SNT2,O75844
Localization
GO Cellular component
msigdb_gocc
128,417,259,263,427,142,115,56,249,58
58,115,427,2023,2790,1674,259,984,2256,2036,1481,417,128,2408,249,263,2610,3376,142,635,56,474,1094
2.8295777132185935,2.2912039487046916,0.9018467708360485,-0.2624237136765148,-0.6254296213866243,-0.12333709979746053,1.4702992943855286,0.21089999179645574,-0.3444696497798871,-0.2624237136765148,-0.04627372815783212,0.9454796834826562,2.2196712726732395,-0.4285051553274654,1.5448699088190703,1.445109921894803,-0.5146374427323911,-1.4359917276919325,2.1362689307517044,0.5326129525524724,2.8559762796306747,0.8279499860422683,0.15734332005004562
3,447
Protein targeting
43
116
2.638556
0.008326
P55786,Q9NS69,O60830,Q99595,Q9Y512,Q8N4H5,O43681,P43307,Q9Y5J9,P51572,P27105,Q15629,Q53H12,O43615,P30536,Q9H270,Q9Y5M8,P57105,P46379,Q9H300,Q9UNL2,O00170,Q15041,O95817,O95140,Q709C8,O60725,Q16543,P61619,Q10713,Q9P0J0,O96008,Q14108,Q15005,P56589,Q15388,Q99442,O14925,Q9BZL1,O75381,Q13438,Q99797,Q9UBE0
Processes and pathways
GO Biological process
msigdb_gobp
516,3,4,9,274,20,531,25,282,404,414,33,549,543,41,562,50,556,179,307,434,435,311,438,437,583,70,469,336,344,87,464,93,349,351,353,360,106,497,491,500,502,511
1188,435,2066,2237,726,1372,106,1096,543,531,2387,70,4,491,2971,2118,2277,437,1914,2280,438,824,464,708,2072,1556,3248,1558,1193,1775,709,414,1516,747,41,1560,882,1292,1873,2128,682,25,179,1294,611,1167,1168,404,516,351,556,3391,1880,1922,336,1012,1824,2711,699,2401,1779,344,3053,1576,1683,500,93,349,311,353,33,1984,469,737,549,1742,2644,583,1348,2096,2823,2153,2824,2412,2379,20,2103,3426,360,1797,1752,9,502,497,562,307,1905,1028,3,1116,87,511,597,1318,1763,1414,2839,1218,434,1322,1155,1768,1862,274,282,50
0.0846519922036011,0.8871862971088242,-0.28275422227728697,-0.3444696497798871,0.4174209793635682,-0.008367163295788871,2.391162989421182,0.13930990831158938,0.6599073521556105,0.6910437992675935,-0.4285051553274654,2.7312521573765434,4.1444590074269065,0.7828838337881776,-0.7632999174742385,-0.30320435577832683,-0.36528796300450794,0.8871862971088242,-0.2221155959941241,-0.36528796300450794,0.8871862971088242,0.3328168814905901,0.8279499860422683,0.4341047300866308,-0.28275422227728697,-0.08459375235902318,-1.0827717031939503,-0.08459375235902318,0.0846519922036011,-0.16251400074754818,0.4341047300866308,0.9454796834826562,-0.06538144972417397,0.4006592727447067,3.0360255403392498,-0.08459375235902318,0.2810765284904778,0.029135457235295485,-0.20213507046424417,-0.30320435577832683,0.46724146702283265,3.396631569290751,1.9195087103543416,0.029135457235295485,0.5648593382990243,0.10296527861463395,0.10296527861463395,0.9599094643624182,0.7219155083838219,1.1011786466586961,0.6442383099094389,-1.5231044801746638,-0.20213507046424417,-0.2221155959941241,1.156206673163405,0.19313737866175912,-0.1822683354853108,-0.5806822940457038,0.45071130368158374,-0.4285051553274654,-0.16251400074754818,1.1287949380852866,-0.8343882553406996,-0.08459375235902318,-0.12333709979746053,0.7677371814906225,2.4886252124811126,1.115012567814737,1.237246593120908,1.1011786466586961,3.216350650152123,-0.24221132899251827,0.8279499860422683,0.4174209793635682,0.6599073521556105,-0.14287070187912912,-0.5365115565809986,0.6126954261187706,0.010434058495094673,-0.28275422227728697,-0.6480246355463081,-0.30320435577832683,-0.6480246355463081,-0.4285051553274654,-0.40730404219216754,3.5912373381541602,-0.28275422227728697,-2.0245641490492052,1.0872927564021313,-0.16251400074754818,-0.14287070187912912,3.8600030048314653,0.7677371814906225,0.7828838337881776,0.6442383099094389,1.2505830026120932,-0.20213507046424417,0.19313737866175912,4.276636208213452,0.13930990831158938,2.5269406716164067,0.7372535957044981,0.5968202922124238,0.029135457235295485,-0.14287070187912912,-0.008367163295788871,-0.6480246355463081,0.0846519922036011,0.9018467708360485,0.029135457235295485,0.12118423630495645,-0.14287070187912912,-0.1822683354853108,1.40700578874686,1.3685099847547963,2.9341371514763055
3,447
Transport vesicle
42
98
2.636892
0.008367
P24390,O43731,Q15907,P20020,P11279,O00461,O60499,Q92542,Q7Z6M1,Q9UEU0,O15400,O76024,Q15437,O95249,Q13190,Q9H0U4,O15498,P61026,P51790,P20339,Q9NR31,P50897,Q9GZM5,P20645,O00429,P61923,P49755,O15260,Q15363,Q15019,Q96A57,P62820,P49257,O60664,Q9Y3B3,P48444,O43493,Q8TBA6,P27695,Q7L0J3,O43760,P10321
Localization
GO Cellular component
msigdb_gocc
0,6,141,403,544,36,423,689,688,564,436,189,715,66,322,452,197,580,448,579,206,77,204,709,588,711,343,88,222,467,91,734,611,605,234,618,243,247,747,123,124,507
588,36,780,864,88,436,197,243,6,1549,124,423,605,2624,3212,1064,1377,189,1913,66,865,1127,1224,1162,1970,2019,1971,507,544,3117,403,579,709,0,747,2813,1337,2130,618,611,343,77,1168,3026,448,846,2498,1521,2453,2898,2638,580,1169,1076,711,1626,734,1522,1269,322,2675,2140,1929,2715,467,850,1832,222,2040,715,141,1106,123,688,872,247,689,1083,91,1797,937,2001,204,452,1029,206,1956,2737,1090,2318,3329,564,1763,1958,1592,234,1157,779
0.5968202922124238,3.184159827888789,0.3668988157742944,0.29840678518812824,2.517396848234407,0.8871862971088242,1.794848233650915,1.593775721781699,3.9547704783957736,-0.08459375235902318,2.2504897475867147,0.9164488273167519,0.5648593382990243,-0.5365115565809986,-1.0316061132826644,0.15734332005004562,-0.008367163295788871,1.840651870597142,-0.2221155959941241,2.7583110565843194,0.29840678518812824,0.12118423630495645,0.06624331600225977,0.10296527861463395,-0.24221132899251827,-0.2624237136765148,-0.24221132899251827,0.7372535957044981,0.6599073521556105,-0.9070004618348723,0.9599094643624182,0.6126954261187706,0.4341047300866308,4.529155521859711,0.4006592727447067,-0.6480246355463081,0.010434058495094673,-0.30320435577832683,0.5487721681964972,0.5648593382990243,1.1287949380852866,2.685738533107751,0.10296527861463395,-0.8105262504581725,0.8576880629169049,0.3156532797160656,-0.471302155269236,-0.06538144972417397,-0.44983727276622243,-0.6936680218939302,-0.5365115565809986,0.6126954261187706,0.10296527861463395,0.15734332005004562,0.4341047300866308,-0.10391188008073553,0.4174209793635682,-0.06538144972417397,0.04773817048517167,1.1969478078787075,-0.5585258554562905,-0.30320435577832683,-0.2221155959941241,-0.5806822940457038,0.8279499860422683,0.3156532797160656,-0.1822683354853108,1.7015526819939406,-0.2624237136765148,0.4341047300866308,2.1362689307517044,0.13930990831158938,2.2607083952402736,0.46724146702283265,0.29840678518812824,1.5571559613224766,0.46724146702283265,0.15734332005004562,2.5078297460632952,-0.16251400074754818,0.2461611801381823,-0.24221132899251827,1.7833107392720506,0.8576880629169049,0.19313737866175912,1.7833107392720506,-0.2221155959941241,-0.5806822940457038,0.15734332005004562,-0.36528796300450794,-1.241143026979425,0.6442383099094389,-0.14287070187912912,-0.2221155959941241,-0.08459375235902318,1.6300436532822637,0.12118423630495645,0.3838188193188344
3,447
Increased bone mineral density
8
24
2.635201
0.008409
Q14739,P48651,P04062,Q9Y4P3,Q15392,Q13126,Q15125,Q14108
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
128,161,97,292,40,170,84,93
1912,2669,97,785,1194,2973,1917,3023,161,749,335,2369,2953,1297,170,93,128,2296,84,40,2985,2172,1094,292
-0.2221155959941241,-0.5585258554562905,2.4693260750464634,0.3668988157742944,0.0846519922036011,-0.7632999174742385,-0.2221155959941241,-0.8105262504581725,2.040236030803411,0.4006592727447067,1.156206673163405,-0.40730404219216754,-0.7399306553991354,0.029135457235295485,1.9748561775908344,2.4886252124811126,2.2196712726732395,-0.36528796300450794,2.555433683915995,3.0610973203490204,-0.7632999174742385,-0.30320435577832683,0.15734332005004562,1.3165577277068716
3,447
Sterol biosynthesis
10
19
2.633461
0.008452
Q14739,Q16850,Q15800,Q15392,P37268,O75845,Q9UBM7,O76062,Q15125,P54646
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
128,164,7,40,199,357,400,115,84,375
357,115,1161,402,199,750,375,3314,1683,2375,128,84,2860,40,581,7,164,400,1505
1.0872927564021313,2.2912039487046916,0.10296527861463395,0.9599094643624182,1.794848233650915,0.4006592727447067,1.0312209548801738,-1.214219613160026,-0.12333709979746053,-0.40730404219216754,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,2.0294163563584418,0.9742827906130651,-0.04627372815783212
3,447
Monovalent inorganic cation homeostasis
12
28
2.629547
0.00855
P51790,Q92544,P55011,P0CG08,Q9Y6M7,P50897,Q9Y5X3,Q93050,O75503,Q9Y487,P05023,Q8N511
Processes and pathways
GO Biological process
msigdb_gobp
448,223,449,514,530,77,334,175,492,149,309,63
492,2122,309,1969,1163,514,949,1517,77,1168,448,828,449,1076,2457,592,63,223,175,1213,2109,912,1763,1253,149,334,3273,530
0.7828838337881776,-0.30320435577832683,1.237246593120908,-0.24221132899251827,0.10296527861463395,0.7219155083838219,0.2285742779294462,-0.06538144972417397,2.685738533107751,0.10296527861463395,0.8576880629169049,0.3328168814905901,0.8576880629169049,0.15734332005004562,-0.44983727276622243,0.5968202922124238,2.776248153122407,1.6897278697989968,1.9417437419205628,0.0846519922036011,-0.28275422227728697,0.2636616261122957,-0.14287070187912912,0.06624331600225977,2.0938827725307765,1.1698368489882653,-1.1086506296557357,0.7065124420438686
3,447
Nuclear membrane
19
63
2.628409
0.008579
Q14739,Q96SK2,P50402,Q8IXM6,P56134,Q14728,O94901,Q9H1E5,Q9BW91,O94919,Q9NRG9,O95168,O15260,Q9BTX1,Q96G23,Q9BVC6,P67812,Q5SNT2,Q6UW68
Localization
Protein Atlas Subcellular
protein_atlas_subcellular_location_all
128,257,259,263,405,417,427,56,446,194,458,453,88,96,103,370,120,249,125
2237,1811,88,2434,3018,2276,2068,427,194,453,1040,515,1609,3118,2023,3322,3001,3002,1778,259,405,1476,120,2083,2036,417,128,2677,2298,2408,249,125,1273,263,1941,2610,634,1993,2648,1995,103,2654,257,909,2799,2873,757,96,370,446,1702,56,1151,458,692,474,2482,1857,2806,1094,2007,2915,944
-0.3444696497798871,-0.1822683354853108,2.517396848234407,-0.44983727276622243,-0.8105262504581725,-0.36528796300450794,-0.28275422227728697,0.9018467708360485,1.8178188702918487,0.8428492678399792,0.17528547971368946,0.7219155083838219,-0.10391188008073553,-0.9070004618348723,-0.2624237136765148,-1.241143026979425,-0.7868309696564781,-0.7868309696564781,-0.16251400074754818,1.4702992943855286,0.9599094643624182,-0.04627372815783212,2.270900210400071,-0.28275422227728697,-0.2624237136765148,0.9454796834826562,2.2196712726732395,-0.5585258554562905,-0.36528796300450794,-0.4285051553274654,1.5448699088190703,2.2504897475867147,0.04773817048517167,1.445109921894803,-0.2221155959941241,-0.5146374427323911,0.5326129525524724,-0.24221132899251827,-0.5365115565809986,-0.24221132899251827,2.410850833556328,-0.5365115565809986,1.482830889777012,0.2636616261122957,-0.6254296213866243,-0.6707700428550947,0.4006592727447067,2.4789875321197483,1.059363369451296,0.8724668990845809,-0.12333709979746053,2.8559762796306747,0.12118423630495645,0.8428492678399792,0.46724146702283265,0.8279499860422683,-0.44983727276622243,-0.1822683354853108,-0.6254296213866243,0.15734332005004562,-0.24221132899251827,-0.6936680218939302,0.2461611801381823
3,447
Cellular hormone metabolic process
11
18
2.627119
0.008611
O95470,Q8TC12,P30536,Q9HB40,Q8NBN7,Q53GQ0,Q8NBQ5,P42892,Q9Y394,Q6UX07,Q6NUM9
Processes and pathways
GO Biological process
msigdb_gobp
65,517,41,108,112,148,373,341,377,250,350
1667,65,1718,41,341,1340,2263,148,350,250,112,373,517,2649,2962,108,536,377
-0.12333709979746053,2.767289755156624,-0.14287070187912912,3.0360255403392498,1.1287949380852866,0.010434058495094673,-0.3444696497798871,2.0938827725307765,1.115012567814737,1.5448699088190703,2.3214620624481643,1.045319009782404,0.7219155083838219,-0.5365115565809986,-0.7399306553991354,2.36144368763533,0.6910437992675935,1.0312209548801738
3,447
Alzheimers disease
16
92
2.623952
0.008692
Q9BVA1,Q9NQC3,P49721,P42574,P07437,Q9BUF5,P16615,P68371,P04350,P45880,P12235,Q9Y277,Q13885,O95197,P12236,P21796
Processes and pathways
WikiPathways
msigdb_wp
34,35,162,229,43,107,136,78,47,16,208,82,52,23,183,27
1961,2386,2945,838,863,2780,2917,839,727,23,47,1040,1970,258,1774,1712,43,1971,1869,208,183,2021,136,2786,2491,2891,1775,980,27,3189,1871,1613,2443,2444,949,1614,2848,522,1673,1517,1291,882,1616,1430,2923,732,229,3094,16,765,710,619,2078,162,1047,2202,1075,2203,1572,2204,2288,1077,78,1779,1297,1886,2085,3362,1827,1780,1103,1578,1580,52,2142,2377,793,2506,966,689,2567,2310,1752,2962,107,34,1456,35,2805,915,82,3245
-0.24221132899251827,-0.4285051553274654,-0.7399306553991354,0.3156532797160656,0.29840678518812824,-0.6254296213866243,-0.7167208001281143,0.3156532797160656,0.4174209793635682,3.4195663235378624,2.9427278149247016,0.17528547971368946,-0.24221132899251827,1.4702992943855286,-0.16251400074754818,-0.14287070187912912,3.002350444101246,-0.24221132899251827,-0.20213507046424417,1.7717381563510717,1.8859120022561358,-0.2624237136765148,2.1572887559147627,-0.6254296213866243,-0.471302155269236,-0.6936680218939302,-0.16251400074754818,0.21089999179645574,3.3503698232892996,-1.0063130127151403,-0.20213507046424417,-0.10391188008073553,-0.44983727276622243,-0.44983727276622243,0.2285742779294462,-0.10391188008073553,-0.6707700428550947,0.7065124420438686,-0.12333709979746053,-0.06538144972417397,0.029135457235295485,0.2810765284904778,-0.10391188008073553,-0.027269365976897105,-0.7167208001281143,0.4174209793635682,1.6420560339548476,-0.8826227148684676,3.6994359897329634,0.3838188193188344,0.4341047300866308,0.5487721681964972,-0.28275422227728697,2.040236030803411,0.17528547971368946,-0.3237756446783554,0.15734332005004562,-0.3237756446783554,-0.08459375235902318,-0.3237756446783554,-0.36528796300450794,0.15734332005004562,2.685738533107751,-0.16251400074754818,0.029135457235295485,-0.20213507046424417,-0.28275422227728697,-1.3791392568827447,-0.1822683354853108,-0.16251400074754818,0.13930990831158938,-0.08459375235902318,-0.08459375235902318,2.890903968218817,-0.30320435577832683,-0.40730404219216754,0.3668988157742944,-0.471302155269236,0.2285742779294462,0.46724146702283265,-0.49290160023430213,-0.36528796300450794,-0.14287070187912912,-0.7399306553991354,2.381281697129018,3.200287370541324,-0.027269365976897105,3.1922316667835537,-0.6254296213866243,0.2636616261122957,2.6118073444066714,-1.0570912841778808
3,447
Respiratory chain
10
35
2.622154
0.008738
Q86Y39,O43676,Q9UDW1,P03886,Q96CU9,O75438,Q9Y6M9,Q9P0J0,O14949,Q9Y241
Processes and pathways
Protein Atlas Biological process
protein_atlas_biological_process
71,8,14,146,180,181,86,87,24,30
2182,1597,24,8,2272,1327,382,706,181,2117,453,3383,2390,568,245,146,1128,578,1228,3336,981,3345,1009,1196,3214,484,3142,1631,1209,71,180,87,14,30,86
-0.3237756446783554,-0.10391188008073553,3.411935775289236,3.873674680039861,-0.36528796300450794,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,0.6126954261187706,0.06624331600225977,-1.2956536049018468,0.21089999179645574,-1.3232487120310719,0.19313737866175912,0.0846519922036011,-1.0316061132826644,0.7979678150313219,-0.9315555215226238,-0.10391188008073553,0.0846519922036011,2.7312521573765434,1.9195087103543416,2.5269406716164067,3.7489696574923244,3.3035742260608005,2.5364613381868493
3,447
Secretory granule membrane
25
69
2.61721
0.008865
Q8NF37,P35613,P30519,O00264,P27105,P11279,Q07065,P07602,Q93050,Q6IAA8,Q9NZJ7,Q5T9A4,Q4KMQ2,Q9NQX7,Q709C8,P61026,Q9Y2Q5,Q9H0U3,P49755,O15260,Q15363,Q969Q5,P42785,P61586,P10321
Localization
GO Cellular component
msigdb_gocc
264,266,12,151,414,544,163,166,175,559,187,451,323,195,583,580,462,325,343,88,222,90,230,240,507
3390,151,1003,88,2581,2623,1036,1865,1377,2241,166,947,507,544,3117,3019,3049,1424,414,12,2705,2497,266,2635,230,1433,343,1622,1168,846,2498,2638,580,1169,3403,240,1729,590,1389,163,889,3157,1732,1930,1484,2142,222,323,1743,451,559,583,264,2564,689,175,90,2799,758,325,1088,195,2737,187,2529,1505,462,2743,1187
-1.5231044801746638,2.0725136772787915,0.19313737866175912,2.517396848234407,-0.5146374427323911,-0.5365115565809986,0.17528547971368946,-0.20213507046424417,-0.008367163295788871,-0.3444696497798871,2.007685211650335,0.2285742779294462,0.7372535957044981,0.6599073521556105,-0.9070004618348723,-0.8105262504581725,-0.8343882553406996,-0.027269365976897105,0.9454796834826562,3.770017295970376,-0.5806822940457038,-0.471302155269236,1.4324515322294316,-0.5365115565809986,1.6420560339548476,-0.027269365976897105,1.1287949380852866,-0.10391188008073553,0.10296527861463395,0.3156532797160656,-0.471302155269236,-0.5365115565809986,0.6126954261187706,0.10296527861463395,-1.6124116985705812,1.6059037631322783,-0.14287070187912912,0.5968202922124238,-0.008367163295788871,2.040236030803411,0.2810765284904778,-0.9562907027938861,-0.14287070187912912,-0.2221155959941241,-0.04627372815783212,-0.30320435577832683,1.7015526819939406,1.1969478078787075,-0.14287070187912912,0.8576880629169049,0.6442383099094389,0.6126954261187706,1.445109921894803,-0.49290160023430213,0.46724146702283265,1.9417437419205628,2.5078297460632952,-0.6254296213866243,0.4006592727447067,1.1969478078787075,0.15734332005004562,1.8178188702918487,-0.5806822940457038,1.8633490032538682,-0.471302155269236,-0.04627372815783212,0.8428492678399792,-0.5806822940457038,0.10296527861463395
3,447
Mitochondrial nucleotide transporter subfamily
10
11
2.615169
0.008918
P05141,Q70HW3,Q86VD7,Q9BSK2,Q9H2D1,Q9HC21,P12235,Q6KCM7,P12236,O43808
Drugs and Diseases
Pharos Drug Target Ontology
pharos_dto
258,72,332,76,46,143,208,306,183,347
347,258,208,183,306,425,72,332,76,46,143
1.115012567814737,1.4702992943855286,1.7717381563510717,1.8859120022561358,1.2505830026120932,0.9164488273167519,2.722191252729754,1.1698368489882653,2.6948832866620145,2.9513000228072084,2.1362689307517044
3,447
Nucleotide transport
10
15
2.59867
0.009359
Q8TB61,P05141,Q86VD7,Q9BSK2,Q9H2D1,Q9HC21,P12235,Q6KCM7,P12236,O43808
Processes and pathways
GO Biological process
msigdb_gobp
64,258,332,76,46,143,208,306,183,347
347,258,208,183,661,889,306,2762,425,332,64,1143,76,46,143
1.115012567814737,1.4702992943855286,1.7717381563510717,1.8859120022561358,0.500075572431892,0.2810765284904778,1.2505830026120932,-0.6029828692428588,0.9164488273167519,1.1698368489882653,2.776248153122407,0.12118423630495645,2.6948832866620145,2.9513000228072084,2.1362689307517044
3,447
Variable expressivity
16
82
2.597893
0.00938
Q9H3H5,O95470,Q9BVA1,P00374,P07602,P17900,Q70HW3,Q9BUF5,Q9H061,P04350,Q9NR77,P03886,Q13885,Q15125,Q13510,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
224,65,34,153,166,198,72,107,13,47,18,146,52,84,121,187
2182,3274,588,1326,2015,3071,437,2946,65,153,245,2669,146,1128,47,2751,979,166,2018,2812,1422,844,198,1562,1977,2130,2894,1777,2594,534,1674,2398,1134,1520,2670,2132,1199,2369,2757,1476,2759,1269,1078,3157,3096,121,2209,2792,52,1105,957,84,2678,2298,549,1936,3174,2510,2265,72,3058,1142,457,857,107,34,13,224,3063,2994,2228,18,1090,187,2659,1060,1708,916,461,640,1285,2180
-0.3237756446783554,-1.1347314072680073,0.5968202922124238,0.010434058495094673,-0.2624237136765148,-0.8584195385239018,0.8871862971088242,-0.7399306553991354,2.767289755156624,2.0617845088395463,1.5694020954564156,-0.5585258554562905,2.1257159606954366,0.12118423630495645,2.9427278149247016,-0.6029828692428588,0.21089999179645574,2.007685211650335,-0.2624237136765148,-0.6480246355463081,-0.027269365976897105,0.3156532797160656,1.794848233650915,-0.08459375235902318,-0.24221132899251827,-0.30320435577832683,-0.6936680218939302,-0.16251400074754818,-0.5146374427323911,0.6910437992675935,-0.12333709979746053,-0.4285051553274654,0.12118423630495645,-0.06538144972417397,-0.5585258554562905,-0.30320435577832683,0.0846519922036011,-0.40730404219216754,-0.6029828692428588,-0.04627372815783212,-0.6029828692428588,0.04773817048517167,0.15734332005004562,-0.9562907027938861,-0.8826227148684676,2.270900210400071,-0.3237756446783554,-0.6254296213866243,2.890903968218817,0.13930990831158938,0.2285742779294462,2.555433683915995,-0.5585258554562905,-0.36528796300450794,0.6599073521556105,-0.2221155959941241,-0.9812088834856775,-0.471302155269236,-0.3444696497798871,2.722191252729754,-0.8343882553406996,0.12118423630495645,0.8428492678399792,0.3156532797160656,2.381281697129018,3.200287370541324,3.7489696574923244,1.6897278697989968,-0.8343882553406996,-0.7632999174742385,-0.3237756446783554,3.642085390164092,0.15734332005004562,1.8633490032538682,-0.5365115565809986,0.17528547971368946,-0.12333709979746053,0.2636616261122957,0.8428492678399792,0.5326129525524724,0.04773817048517167,-0.30320435577832683
3,447
Organophosphate ester transport
15
31
2.595284
0.009451
Q8TB61,Q4KMQ2,P05141,P08183,Q9BSK2,Q9H2D1,Q9HC21,Q86VD7,P12235,Q6KCM7,Q7Z3C6,Q8WTV0,P12236,O43808,Q14108
Processes and pathways
GO Biological process
msigdb_gobp
64,323,258,299,76,46,143,332,208,306,176,241,183,347,93
347,3435,258,299,208,183,1290,2441,1231,661,1132,557,524,2206,889,93,323,306,2762,425,176,332,64,1143,241,76,3350,46,143,2737,2529
1.115012567814737,-2.89120220745136,1.4702992943855286,1.2771132720400578,1.7717381563510717,1.8859120022561358,0.029135457235295485,-0.44983727276622243,0.06624331600225977,0.500075572431892,0.12118423630495645,0.6442383099094389,0.7065124420438686,-0.3237756446783554,0.2810765284904778,2.4886252124811126,1.1969478078787075,1.2505830026120932,-0.6029828692428588,0.9164488273167519,1.9306423672509032,1.1698368489882653,2.776248153122407,0.12118423630495645,1.6059037631322783,2.6948832866620145,-1.3232487120310719,2.9513000228072084,2.1362689307517044,-0.5806822940457038,-0.471302155269236
3,447
Cholesterol biosynthesis
10
18
2.591541
0.009555
Q14739,Q14534,Q16850,Q15800,Q15392,O75845,P37268,Q9UBM7,O76062,Q15125
Processes and pathways
Reactome Pathways
msigdb_reactome
128,130,164,7,40,357,199,400,115,84
357,115,402,199,1621,750,3314,2375,130,128,84,2860,40,581,7,164,1359,400
1.0872927564021313,2.2912039487046916,0.9599094643624182,1.794848233650915,-0.10391188008073553,0.4006592727447067,-1.214219613160026,-0.40730404219216754,2.1886057148305667,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,2.0294163563584418,0.010434058495094673,0.9742827906130651
3,447
Abnormal social behavior
13
68
2.589512
0.009611
P07602,Q86Y39,O43676,Q5XKP0,Q15907,Q9UHX1,P03886,Q96CU9,Q15125,Q9Y6M9,Q9P0J0,Q2TAA5,Q9NZJ7
Drugs and Diseases
Human Phenotype Ontology
msigdb_hp
166,71,8,137,141,110,146,180,84,86,87,184,187
2182,8,531,1912,1814,1327,382,706,2117,1669,1968,568,464,146,1970,166,1608,844,785,3336,1194,730,1917,3345,1429,3023,3214,3080,1233,1199,2953,1438,1887,1575,2335,2296,663,84,671,141,1585,184,2821,137,583,71,874,815,180,1084,875,1495,2051,3388,2688,2875,1182,193,2834,187,3039,87,110,2172,2805,2179,292,86
-0.3237756446783554,3.873674680039861,0.6910437992675935,-0.2221155959941241,-0.1822683354853108,0.010434058495094673,1.0028619724328278,0.4341047300866308,-0.30320435577832683,-0.12333709979746053,-0.24221132899251827,0.6285012150671874,0.8279499860422683,2.1257159606954366,-0.24221132899251827,2.007685211650335,-0.10391188008073553,0.3156532797160656,0.3668988157742944,-1.2956536049018468,0.0846519922036011,0.4174209793635682,-0.2221155959941241,-1.3232487120310719,-0.027269365976897105,-0.8105262504581725,-1.0316061132826644,-0.8584195385239018,0.06624331600225977,0.0846519922036011,-0.7399306553991354,-0.027269365976897105,-0.20213507046424417,-0.08459375235902318,-0.3862322082359554,-0.36528796300450794,0.500075572431892,2.555433683915995,0.4836959753352828,2.1362689307517044,-0.08459375235902318,1.8859120022561358,-0.6480246355463081,2.1572887559147627,0.6126954261187706,2.7312521573765434,0.29840678518812824,0.349898446135214,1.9195087103543416,0.15734332005004562,0.29840678518812824,-0.04627372815783212,-0.2624237136765148,-1.4938226351232837,-0.5585258554562905,-0.6707700428550947,0.10296527861463395,1.8292524636194953,-0.6480246355463081,1.8633490032538682,-0.8105262504581725,2.5269406716164067,2.3415041854178815,-0.30320435577832683,-0.6254296213866243,-0.30320435577832683,1.3165577277068716,2.5364613381868493
3,447
Amyloid precursor protein metabolic process
7
21
2.58084
0.009856
P35610,Q9NQC3,Q9NQX7,P42574,Q15392,Q16799,O95197
Processes and pathways
GO Biological process
msigdb_gobp
321,35,195,229,40,119,23
2667,23,1715,1558,747,321,229,343,1886,700,1579,2140,1484,40,119,689,2827,2308,35,195,3107
-0.5585258554562905,3.4195663235378624,-0.14287070187912912,-0.08459375235902318,0.4006592727447067,1.1969478078787075,1.6420560339548476,1.1287949380852866,-0.20213507046424417,0.45071130368158374,-0.08459375235902318,-0.30320435577832683,-0.04627372815783212,3.0610973203490204,2.2810653447612044,0.46724146702283265,-0.6480246355463081,-0.36528796300450794,3.1922316667835537,1.8178188702918487,-0.8826227148684676
3,447
Protein transporter activity
9
14
2.579754
0.009887
Q9NS69,O60830,Q9HD20,Q99595,Q07820,O14925,P61619,P49755,Q9Y5J9
Functions
GO Molecular function
msigdb_gomf
3,4,102,9,300,106,336,343,282
106,4,2277,464,343,336,300,353,1112,9,102,3,597,282
2.391162989421182,4.1444590074269065,-0.36528796300450794,0.8279499860422683,1.1287949380852866,1.156206673163405,1.2771132720400578,1.1011786466586961,0.13930990831158938,3.8600030048314653,2.42065765575822,4.276636208213452,0.5968202922124238,1.3685099847547963
3,447
Nucleotide transmembrane transporter activity
10
12
2.576749
0.009973
Q8TB61,P05141,Q86VD7,Q9BSK2,Q9H2D1,Q9HC21,P12235,Q6KCM7,P12236,O43808
Functions
GO Molecular function
msigdb_gomf
64,258,332,76,46,143,208,306,183,347
347,258,208,183,661,306,425,332,64,76,46,143
1.115012567814737,1.4702992943855286,1.7717381563510717,1.8859120022561358,0.500075572431892,1.2505830026120932,0.9164488273167519,1.1698368489882653,2.776248153122407,2.6948832866620145,2.9513000228072084,2.1362689307517044
3,447
Organophosphate ester transmembrane transporter activity
10
12
2.576749
0.009973
Q8TB61,P05141,Q86VD7,Q9BSK2,Q9H2D1,Q9HC21,P12235,Q6KCM7,P12236,O43808
Functions
GO Molecular function
msigdb_gomf
64,258,332,76,46,143,208,306,183,347
347,258,208,183,661,306,425,332,64,76,46,143
1.115012567814737,1.4702992943855286,1.7717381563510717,1.8859120022561358,0.500075572431892,1.2505830026120932,0.9164488273167519,1.1698368489882653,2.776248153122407,2.6948832866620145,2.9513000228072084,2.1362689307517044
3,447
Respiratory electron transport chain
19
52
2.573547
0.010066
O75306,O43676,Q9UDW1,P21912,P03886,O14949,Q99643,O75438,O96000,O95168,Q9Y6M9,P13073,O43819,P04062,Q9H3K2,P51970,P00403,Q16134,P20674
Processes and pathways
GO Biological process
msigdb_gobp
382,8,14,270,146,24,432,181,568,453,86,89,340,97,225,484,245,504,508
2182,1597,24,8,2272,340,1327,382,706,181,2117,1669,453,3383,2390,568,245,146,1128,97,3138,1006,578,1422,879,89,3230,1066,1228,922,3336,508,270,3345,2495,3171,1232,1196,3214,484,2145,504,3142,1631,2688,432,1647,225,1501,14,1660,86
-0.3237756446783554,-0.10391188008073553,3.411935775289236,3.873674680039861,-0.36528796300450794,1.1287949380852866,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,-0.12333709979746053,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,2.4693260750464634,-0.9315555215226238,0.19313737866175912,0.6126954261187706,-0.027269365976897105,0.2810765284904778,2.517396848234407,-1.0570912841778808,0.15734332005004562,0.06624331600225977,0.2461611801381823,-1.2956536049018468,0.7372535957044981,1.40700578874686,-1.3232487120310719,-0.471302155269236,-0.9812088834856775,0.06624331600225977,0.0846519922036011,-1.0316061132826644,0.7979678150313219,-0.30320435577832683,0.75252729309868,-0.9315555215226238,-0.10391188008073553,-0.5585258554562905,0.9018467708360485,-0.10391188008073553,1.6659669752722266,-0.04627372815783212,3.7489696574923244,-0.10391188008073553,2.5364613381868493
3,447