term
stringlengths 2
121
| overlap
int64 6
281
| setsize
int64 7
499
| score
float64 1.96
10.6
| pval
float64 0
0.05
| edge
stringlengths 41
1.97k
| type
stringclasses 5
values | subtype
stringclasses 24
values | subtype_key
stringclasses 24
values | edge_idxs
stringlengths 11
1.17k
| ann_idxs
stringlengths 19
2.31k
| ann_vals
stringlengths 124
9.94k
| sig_size
int64 2.2k
3.73k
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Outer mitochondrial membrane protein complex
| 12
| 16
| 2.562601
| 0.010389
|
Q8IWA4,Q15388,Q9NS69,Q9NVH1,Q5XKP0,Q9Y512,Q13505,Q9BUR5,Q8N4H5,Q6UXV4,O96008,O75431
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
256,353,3,489,137,274,407,147,20,213,464,413
|
413,2277,464,3119,407,353,558,137,213,256,20,147,3,489,1364,274
|
0.9454796834826562,-0.36528796300450794,0.8279499860422683,-0.9070004618348723,0.9599094643624182,1.1011786466586961,0.6442383099094389,2.1572887559147627,1.7250922784124725,1.4953208273418972,3.5912373381541602,2.1045230542075872,4.276636208213452,0.7979678150313219,0.010434058495094673,1.40700578874686
| 3,447
|
Microtubules
| 7
| 57
| 2.56142
| 0.010425
|
Q9BVA1,O60830,Q02818,P07437,P68371,P04350,Q13885
|
Localization
|
Protein Atlas Subcellular
|
protein_atlas_subcellular_location_all
|
34,4,38,43,78,47,52
|
2386,2622,4,606,2067,47,43,1098,2589,2813,1068,2592,1069,3028,789,1879,1477,78,1522,791,38,1682,1013,1580,2294,2209,52,1104,1785,338,1789,1208,3218,582,583,2905,2863,3280,2685,3034,1945,770,3102,1752,107,34,2054,2353,1956,1411,1217,738,3146,1031,975,586,3109
|
-0.4285051553274654,-0.5365115565809986,4.1444590074269065,0.5648593382990243,-0.28275422227728697,2.9427278149247016,3.002350444101246,0.13930990831158938,-0.5146374427323911,-0.6480246355463081,0.15734332005004562,-0.5146374427323911,0.15734332005004562,-0.8105262504581725,0.3668988157742944,-0.20213507046424417,-0.04627372815783212,2.685738533107751,-0.06538144972417397,0.3668988157742944,3.1679674644036484,-0.12333709979746053,0.19313737866175912,-0.08459375235902318,-0.36528796300450794,-0.3237756446783554,2.890903968218817,0.13930990831158938,-0.16251400074754818,1.1425261705350076,-0.16251400074754818,0.0846519922036011,-1.0316061132826644,0.6126954261187706,0.6126954261187706,-0.6936680218939302,-0.6707700428550947,-1.1347314072680073,-0.5585258554562905,-0.8105262504581725,-0.2221155959941241,0.3838188193188344,-0.8826227148684676,-0.14287070187912912,2.381281697129018,3.200287370541324,-0.2624237136765148,-0.3862322082359554,-0.2221155959941241,-0.008367163295788871,0.0846519922036011,0.4174209793635682,-0.9315555215226238,0.19313737866175912,0.2285742779294462,0.6126954261187706,-0.8826227148684676
| 3,447
|
Golgi membrane
| 46
| 135
| 2.554612
| 0.010631
|
P24390,Q8N4V1,O43731,Q96L58,Q8NF37,Q9Y3E0,P35613,Q9BUR5,Q6ZRP7,O95197,P51572,Q9Y282,Q9UM00,Q99640,O00461,O60499,Q15392,O95070,Q969X5,Q10472,Q7Z3C6,Q8IV08,Q9H1C4,Q8TB61,Q9H0U4,O95249,Q13190,Q9P2W9,O15498,P51790,Q9H7Z7,Q10713,P49755,P98194,O15260,Q15363,O15258,Q14108,L0R6Q1,Q6NTF9,Q9Y3B3,Q9NTJ5,Q8TBA6,Q16799,Q9H4A6,Q7LGA3
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,5,6,390,264,393,266,147,409,23,404,26,285,419,36,423,40,171,429,305,176,313,192,64,452,66,322,68,197,448,202,344,343,215,88,222,219,93,217,231,234,371,247,119,251,126
|
217,36,780,726,864,219,88,197,577,1601,6,1549,668,423,2624,1064,171,23,66,3047,1162,2074,514,507,844,3117,1290,0,1337,266,2250,2025,732,618,1132,611,343,883,404,448,1101,3305,2498,1521,3095,3120,1879,2898,953,580,1169,711,1626,2454,734,3347,1480,215,2979,3217,2292,1173,1575,305,1888,344,1174,322,1579,93,2143,1526,3124,1832,222,40,2040,593,119,1106,231,409,126,176,2153,872,313,2415,5,1241,1452,264,64,247,1994,1691,2105,2869,429,1697,624,390,3206,419,147,2001,2521,758,452,192,1500,251,202,1029,1853,1956,371,692,2529,460,68,2318,637,1763,3067,1764,285,26,1592,2534,3262,1155,234,393,1157
|
1.7015526819939406,3.184159827888789,0.3668988157742944,0.4174209793635682,0.29840678518812824,1.7015526819939406,2.517396848234407,1.794848233650915,0.6126954261187706,-0.10391188008073553,3.9547704783957736,-0.08459375235902318,0.4836959753352828,0.9164488273167519,-0.5365115565809986,0.15734332005004562,1.9638504485042398,3.4195663235378624,2.7583110565843194,-0.8343882553406996,0.10296527861463395,-0.28275422227728697,0.7219155083838219,0.7372535957044981,0.3156532797160656,-0.9070004618348723,0.029135457235295485,4.529155521859711,0.010434058495094673,1.4324515322294316,-0.3444696497798871,-0.2624237136765148,0.4174209793635682,0.5487721681964972,0.12118423630495645,0.5648593382990243,1.1287949380852866,0.2810765284904778,0.9599094643624182,0.8576880629169049,0.13930990831158938,-1.1875123306433095,-0.471302155269236,-0.06538144972417397,-0.8826227148684676,-0.9070004618348723,-0.20213507046424417,-0.6936680218939302,0.2285742779294462,0.6126954261187706,0.10296527861463395,0.4341047300866308,-0.10391188008073553,-0.44983727276622243,0.4174209793635682,-1.3232487120310719,-0.04627372815783212,1.7133407362411066,-0.7632999174742385,-1.0316061132826644,-0.36528796300450794,0.10296527861463395,-0.08459375235902318,1.2505830026120932,-0.20213507046424417,1.1287949380852866,0.10296527861463395,1.1969478078787075,-0.08459375235902318,2.4886252124811126,-0.30320435577832683,-0.06538144972417397,-0.9070004618348723,-0.1822683354853108,1.7015526819939406,3.0610973203490204,-0.2624237136765148,0.5968202922124238,2.2810653447612044,0.13930990831158938,1.6420560339548476,0.9599094643624182,2.229971341354025,1.9306423672509032,-0.30320435577832683,0.29840678518812824,1.237246593120908,-0.4285051553274654,4.040872839878629,0.06624331600225977,-0.027269365976897105,1.445109921894803,2.776248153122407,1.5571559613224766,-0.24221132899251827,-0.12333709979746053,-0.28275422227728697,-0.6707700428550947,0.9018467708360485,-0.12333709979746053,0.5487721681964972,0.9886001370636728,-1.0063130127151403,0.9454796834826562,2.1045230542075872,-0.24221132899251827,-0.471302155269236,0.4006592727447067,0.8576880629169049,1.8292524636194953,-0.04627372815783212,1.5325436558776693,1.794848233650915,0.19313737866175912,-0.1822683354853108,-0.2221155959941241,1.059363369451296,0.46724146702283265,-0.471302155269236,0.8428492678399792,2.7583110565843194,-0.36528796300450794,0.5326129525524724,-0.14287070187912912,-0.8343882553406996,-0.14287070187912912,1.3555894999858193,3.396631569290751,-0.08459375235902318,-0.471302155269236,-1.0827717031939503,0.12118423630495645,1.6300436532822637,0.9886001370636728,0.12118423630495645
| 3,447
|
Ceramide metabolic process
| 9
| 21
| 2.553613
| 0.010661
|
O95470,P04062,P17900,Q96G23,O15269,Q99805,Q13510,Q16880,P27544
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
65,97,198,103,239,182,121,122,61
|
239,628,65,97,1225,2327,3428,198,2999,61,1264,2206,1683,121,122,549,289,103,2829,182,692
|
1.6059037631322783,0.5326129525524724,2.767289755156624,2.4693260750464634,0.06624331600225977,-0.3862322082359554,-2.333607799065281,1.794848233650915,-0.7868309696564781,2.7851863493439573,0.04773817048517167,-0.3237756446783554,-0.12333709979746053,2.270900210400071,2.270900210400071,0.6599073521556105,1.3296137106483024,2.410850833556328,-0.6480246355463081,1.9083425678170867,0.46724146702283265
| 3,447
|
Autophagy of mitochondrion
| 14
| 33
| 2.547265
| 0.010857
|
P04062,Q709C8,P05141,Q9BWH2,P30536,Q99623,Q16543,P12235,Q7Z3C6,Q9H300,O00429,O95140,P21796,P27544
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
97,583,258,227,41,271,469,208,176,307,588,437,27,61
|
898,588,437,1867,97,2843,258,208,1775,27,61,41,2198,1474,612,3120,2956,469,583,1531,176,2153,1402,2688,271,227,307,862,1116,1414,1768,2115,3245
|
0.2636616261122957,0.5968202922124238,0.8871862971088242,-0.20213507046424417,2.4693260750464634,-0.6707700428550947,1.4702992943855286,1.7717381563510717,-0.16251400074754818,3.3503698232892996,2.7851863493439573,3.0360255403392498,-0.3237756446783554,-0.04627372815783212,0.5648593382990243,-0.9070004618348723,-0.7399306553991354,0.8279499860422683,0.6126954261187706,-0.06538144972417397,1.9306423672509032,-0.30320435577832683,-0.008367163295788871,-0.5585258554562905,1.40700578874686,1.6540303882823562,1.2505830026120932,0.3156532797160656,0.13930990831158938,-0.008367163295788871,-0.14287070187912912,-0.28275422227728697,-1.0570912841778808
| 3,447
|
Respiratory electron transport
| 21
| 53
| 2.54426
| 0.010951
|
O75306,O43676,Q9UDW1,P21912,O75880,P03886,O14949,Q99643,O75438,O96000,Q9NPL8,Q86Y39,O95168,Q9Y6M9,Q9P0J0,P13073,O43819,P51970,P00403,Q16134,P20674
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
382,8,14,270,520,146,24,432,181,568,193,71,453,86,87,89,340,484,245,504,508
|
2182,1597,24,8,2272,340,1327,382,706,181,2117,520,453,3383,2390,568,245,146,1128,578,802,879,89,3230,1228,922,3336,508,270,981,3345,2495,1009,3171,2790,1196,3214,484,2257,504,3142,1631,71,432,910,3061,2875,2656,193,3039,87,14,86
|
-0.3237756446783554,-0.10391188008073553,3.411935775289236,3.873674680039861,-0.36528796300450794,1.1287949380852866,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,0.7065124420438686,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,0.6126954261187706,0.349898446135214,0.2810765284904778,2.517396848234407,-1.0570912841778808,0.06624331600225977,0.2461611801381823,-1.2956536049018468,0.7372535957044981,1.40700578874686,0.21089999179645574,-1.3232487120310719,-0.471302155269236,0.19313737866175912,-0.9812088834856775,-0.6254296213866243,0.0846519922036011,-1.0316061132826644,0.7979678150313219,-0.3444696497798871,0.75252729309868,-0.9315555215226238,-0.10391188008073553,2.7312521573765434,0.9018467708360485,0.2636616261122957,-0.8343882553406996,-0.6707700428550947,-0.5365115565809986,1.8292524636194953,-0.8105262504581725,2.5269406716164067,3.7489696574923244,2.5364613381868493
| 3,447
|
oxidase
| 10
| 16
| 2.544012
| 0.010959
|
P13073,P14406,Q15800,O75845,Q6QHF9,Q6ZRP7,O43819,P27338,P36551,P20674
|
Functions
|
Panther Protein class
|
panther_protein_class
|
89,1,7,357,111,409,340,221,477,508
|
340,1813,357,520,879,89,1,922,508,221,477,748,7,111,409,814
|
1.1287949380852866,-0.1822683354853108,1.0872927564021313,0.7065124420438686,0.2810765284904778,2.517396848234407,4.313649129144161,0.2461611801381823,0.7372535957044981,1.7015526819939406,0.8129896825372822,0.4006592727447067,3.9211731425024707,2.3314960227808297,0.9599094643624182,0.349898446135214
| 3,447
|
Regulation of hormone levels
| 19
| 66
| 2.517757
| 0.01181
|
Q15907,O95563,P16435,Q53GQ0,P30536,O75844,P05023,P50416,O95470,Q8N5M9,P42892,Q6NUM9,Q9HB40,Q06520,P53985,Q8NBN7,Q8NBQ5,Q9Y394,Q6UX07
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
141,269,275,148,41,58,309,316,65,85,341,350,108,238,237,112,373,377,250
|
3390,1547,2945,3274,3089,1965,1667,58,65,269,1192,2121,309,1715,2018,2021,1718,275,867,1290,41,2705,1519,341,3380,316,1340,846,237,3156,734,3407,3347,1522,1926,238,1827,2504,929,2263,141,2862,1787,148,350,250,2644,1020,85,112,373,966,517,2649,2468,859,2420,518,2688,2962,108,536,400,1366,741,377
|
-1.5231044801746638,-0.08459375235902318,-0.7399306553991354,-1.1347314072680073,-0.8826227148684676,-0.24221132899251827,-0.12333709979746053,2.8295777132185935,2.767289755156624,1.40700578874686,0.0846519922036011,-0.30320435577832683,1.237246593120908,-0.14287070187912912,-0.2624237136765148,-0.2624237136765148,-0.14287070187912912,1.3942178014247664,0.29840678518812824,0.029135457235295485,3.0360255403392498,-0.5806822940457038,-0.06538144972417397,1.1287949380852866,-1.4647849416373495,1.2238621747785425,0.010434058495094673,0.3156532797160656,1.6179929845170453,-0.9562907027938861,0.4174209793635682,-1.673164747906431,-1.3232487120310719,-0.06538144972417397,-0.2221155959941241,1.6179929845170453,-0.1822683354853108,-0.471302155269236,0.2461611801381823,-0.3444696497798871,2.1362689307517044,-0.6707700428550947,-0.16251400074754818,2.0938827725307765,1.115012567814737,1.5448699088190703,-0.5365115565809986,0.19313737866175912,2.555433683915995,2.3214620624481643,1.045319009782404,0.2285742779294462,0.7219155083838219,-0.5365115565809986,-0.44983727276622243,0.3156532797160656,-0.4285051553274654,0.7219155083838219,-0.5585258554562905,-0.7399306553991354,2.36144368763533,0.6910437992675935,0.9742827906130651,0.010434058495094673,0.4174209793635682,1.0312209548801738
| 3,447
|
Impaired social interactions
| 10
| 49
| 2.511125
| 0.012035
|
Q86Y39,O43676,Q5XKP0,Q15907,Q9UHX1,P03886,Q96CU9,Q9Y6M9,Q9P0J0,Q2TAA5
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
71,8,137,141,110,146,180,86,87,184
|
2182,8,1327,382,706,2117,1669,1968,568,146,1608,844,3336,730,3345,1429,3214,3080,1233,1199,1438,1887,1575,2335,663,141,1585,184,2821,137,583,71,874,815,180,1084,875,1495,2051,3388,2688,2875,1182,193,2834,3039,87,110,86
|
-0.3237756446783554,3.873674680039861,0.010434058495094673,1.0028619724328278,0.4341047300866308,-0.30320435577832683,-0.12333709979746053,-0.24221132899251827,0.6285012150671874,2.1257159606954366,-0.10391188008073553,0.3156532797160656,-1.2956536049018468,0.4174209793635682,-1.3232487120310719,-0.027269365976897105,-1.0316061132826644,-0.8584195385239018,0.06624331600225977,0.0846519922036011,-0.027269365976897105,-0.20213507046424417,-0.08459375235902318,-0.3862322082359554,0.500075572431892,2.1362689307517044,-0.08459375235902318,1.8859120022561358,-0.6480246355463081,2.1572887559147627,0.6126954261187706,2.7312521573765434,0.29840678518812824,0.349898446135214,1.9195087103543416,0.15734332005004562,0.29840678518812824,-0.04627372815783212,-0.2624237136765148,-1.4938226351232837,-0.5585258554562905,-0.6707700428550947,0.10296527861463395,1.8292524636194953,-0.6480246355463081,-0.8105262504581725,2.5269406716164067,2.3415041854178815,2.5364613381868493
| 3,447
|
Sphingolipid metabolism integrated pathway
| 6
| 8
| 2.510522
| 0.012055
|
O95470,Q96G23,Q06136,Q13510,Q16880,P27544
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
65,103,200,121,122,61
|
239,628,65,61,200,121,122,103
|
1.6059037631322783,0.5326129525524724,2.767289755156624,2.7851863493439573,1.794848233650915,2.270900210400071,2.270900210400071,2.410850833556328
| 3,447
|
Sphingolipid metabolism overview
| 6
| 8
| 2.510522
| 0.012055
|
O95470,Q96G23,Q06136,Q13510,Q16880,P27544
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
65,103,200,121,122,61
|
239,628,65,61,200,121,122,103
|
1.6059037631322783,0.5326129525524724,2.767289755156624,2.7851863493439573,1.794848233650915,2.270900210400071,2.270900210400071,2.410850833556328
| 3,447
|
Inorganic anion transport
| 13
| 25
| 2.503658
| 0.012292
|
P51790,Q4KMQ2,Q00325,P0CG08,P55011,Q9Y6M7,P30536,P08183,Q9UHG3,P45880,Q9Y277,P21796,Q9UBX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
448,323,450,514,449,530,41,299,44,16,82,27,31
|
1909,531,299,514,27,41,1231,16,448,749,3028,449,450,829,323,3434,2762,1143,912,2380,31,44,82,3273,530
|
-0.2221155959941241,0.6910437992675935,1.2771132720400578,0.7219155083838219,3.3503698232892996,3.0360255403392498,0.06624331600225977,3.6994359897329634,0.8576880629169049,0.4006592727447067,-0.8105262504581725,0.8576880629169049,0.8576880629169049,0.3328168814905901,1.1969478078787075,-2.5135956035021803,-0.6029828692428588,0.12118423630495645,0.2636616261122957,-0.40730404219216754,3.272073939679055,2.9683894129100112,2.6118073444066714,-1.1086506296557357,0.7065124420438686
| 3,447
|
Sphingolipid pathway
| 6
| 9
| 2.501817
| 0.012356
|
O95470,P04062,Q96G23,Q06136,Q13510,Q16880
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
65,97,103,200,121,122
|
239,628,65,97,2034,200,121,122,103
|
1.6059037631322783,0.5326129525524724,2.767289755156624,2.4693260750464634,-0.2624237136765148,1.794848233650915,2.270900210400071,2.270900210400071,2.410850833556328
| 3,447
|
Rigidity
| 8
| 57
| 2.498151
| 0.012484
|
P04062,Q9H6K4,P07602,Q15392,P04350,P12235,Q96CU9,Q9NZJ7
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
97,67,166,40,47,208,180,187
|
2185,531,1865,2239,2279,2750,97,47,166,208,866,1332,2891,1009,1977,3322,2130,2198,2398,1778,3080,2670,2132,2287,1012,1269,2404,2037,1887,1827,890,1104,40,211,2043,583,1239,833,1112,1694,180,1644,501,1057,2051,2688,2770,1540,1360,67,2834,187,1366,1184,916,1285,2180
|
-0.3237756446783554,0.6910437992675935,-0.20213507046424417,-0.3444696497798871,-0.36528796300450794,-0.6029828692428588,2.4693260750464634,2.9427278149247016,2.007685211650335,1.7717381563510717,0.29840678518812824,0.010434058495094673,-0.6936680218939302,0.19313737866175912,-0.24221132899251827,-1.241143026979425,-0.30320435577832683,-0.3237756446783554,-0.4285051553274654,-0.16251400074754818,-0.8584195385239018,-0.5585258554562905,-0.30320435577832683,-0.36528796300450794,0.19313737866175912,0.04773817048517167,-0.4285051553274654,-0.2624237136765148,-0.20213507046424417,-0.1822683354853108,0.2810765284904778,0.13930990831158938,3.0610973203490204,1.7368075518613622,-0.2624237136765148,0.6126954261187706,0.06624331600225977,0.3328168814905901,0.13930990831158938,-0.12333709979746053,1.9195087103543416,-0.10391188008073553,0.7677371814906225,0.17528547971368946,-0.2624237136765148,-0.5585258554562905,-0.6029828692428588,-0.06538144972417397,0.010434058495094673,2.7583110565843194,-0.6480246355463081,1.8633490032538682,0.010434058495094673,0.10296527861463395,0.2636616261122957,0.04773817048517167,-0.30320435577832683
| 3,447
|
Sterol metabolism
| 17
| 29
| 2.496742
| 0.012534
|
Q14739,P35610,P04062,Q16850,Q15800,Q15392,O15118,P37268,Q9UBM7,O75845,P61916,O76062,Q15125,O94905,P14324,O75477,P54646
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
128,321,97,164,7,40,186,199,400,357,557,115,84,463,402,476,375
|
186,476,357,115,463,1161,3435,97,402,2846,321,199,750,375,557,3006,3314,1683,2375,128,84,2860,40,581,7,164,400,2775,1505
|
1.8633490032538682,0.8129896825372822,1.0872927564021313,2.2912039487046916,0.8279499860422683,0.10296527861463395,-2.89120220745136,2.4693260750464634,0.9599094643624182,-0.6707700428550947,1.1969478078787075,1.794848233650915,0.4006592727447067,1.0312209548801738,0.6442383099094389,-0.7868309696564781,-1.214219613160026,-0.12333709979746053,-0.40730404219216754,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,2.0294163563584418,0.9742827906130651,-0.6029828692428588,-0.04627372815783212
| 3,447
|
Rough endoplasmic reticulum
| 19
| 34
| 2.491737
| 0.012712
|
Q07020,P36578,P04844,Q07065,Q96A33,Q9Y5M8,Q15041,P62266,Q9UQB8,Q9UGP8,P61619,Q8TCT9,P51571,Q5BJF2,Q99442,P04843,Q5VV42,Q9UBF8,P27824
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
647,643,537,163,178,50,311,572,320,597,336,92,226,100,360,607,372,637,509
|
2620,642,1328,607,537,1970,1331,1720,509,827,643,1167,226,3391,1169,2032,336,572,3419,2899,1681,1682,647,163,311,100,372,92,178,360,637,597,320,50
|
-0.5365115565809986,0.5163809909451085,0.010434058495094673,0.5648593382990243,0.6755089741541659,-0.24221132899251827,0.010434058495094673,-0.14287070187912912,0.7372535957044981,0.3328168814905901,0.5163809909451085,0.10296527861463395,1.6540303882823562,-1.5231044801746638,0.10296527861463395,-0.2624237136765148,1.156206673163405,0.6285012150671874,-1.861228443273181,-0.6936680218939302,-0.12333709979746053,-0.12333709979746053,0.5163809909451085,2.040236030803411,1.237246593120908,2.42065765575822,1.045319009782404,2.498239242135206,1.9306423672509032,1.0872927564021313,0.5326129525524724,0.5968202922124238,1.2104293727985382,2.9341371514763055
| 3,447
|
Steroid metabolism
| 18
| 31
| 2.491058
| 0.012736
|
Q14739,P35610,P04062,Q16850,Q15800,Q15392,O15118,P37268,Q9UBM7,O75845,Q06520,P61916,O76062,Q15125,O94905,P14324,O75477,P54646
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
128,321,97,164,7,40,186,199,400,357,238,557,115,84,463,402,476,375
|
186,476,357,115,463,1161,3435,97,402,2846,321,199,750,375,557,3006,3314,238,1683,2375,128,84,2860,40,581,7,164,2962,400,2775,1505
|
1.8633490032538682,0.8129896825372822,1.0872927564021313,2.2912039487046916,0.8279499860422683,0.10296527861463395,-2.89120220745136,2.4693260750464634,0.9599094643624182,-0.6707700428550947,1.1969478078787075,1.794848233650915,0.4006592727447067,1.0312209548801738,0.6442383099094389,-0.7868309696564781,-1.214219613160026,1.6179929845170453,-0.12333709979746053,-0.40730404219216754,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,2.0294163563584418,-0.7399306553991354,0.9742827906130651,-0.6029828692428588,-0.04627372815783212
| 3,447
|
Electron transport chain
| 23
| 70
| 2.480718
| 0.013112
|
O75306,O43175,O43676,Q9UDW1,P21912,P03886,P16435,O14949,Q99643,O75438,O96000,O95168,Q9Y6M9,Q9P0J0,P13073,O43819,P27338,P04062,Q9H3K2,P51970,P00403,Q16134,P20674
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
382,512,8,14,270,146,275,24,432,181,568,453,86,87,89,340,221,97,225,484,245,504,508
|
2182,1597,24,512,1600,8,2272,340,840,1327,382,706,181,2117,1669,453,3383,2390,568,2583,245,146,1128,97,3138,2972,1006,578,2812,1422,879,2585,89,3230,1066,1228,1718,922,275,3336,508,270,2632,2024,221,3345,2194,2495,3171,1232,1196,2595,3214,484,1781,632,2145,504,3142,1631,2409,2688,432,1647,225,1501,87,14,1660,86
|
-0.3237756446783554,-0.10391188008073553,3.411935775289236,0.7219155083838219,-0.10391188008073553,3.873674680039861,-0.36528796300450794,1.1287949380852866,0.3156532797160656,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,-0.12333709979746053,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,-0.5146374427323911,1.5694020954564156,2.1257159606954366,0.12118423630495645,2.4693260750464634,-0.9315555215226238,-0.7632999174742385,0.19313737866175912,0.6126954261187706,-0.6480246355463081,-0.027269365976897105,0.2810765284904778,-0.5146374427323911,2.517396848234407,-1.0570912841778808,0.15734332005004562,0.06624331600225977,-0.14287070187912912,0.2461611801381823,1.3942178014247664,-1.2956536049018468,0.7372535957044981,1.40700578874686,-0.5365115565809986,-0.2624237136765148,1.7015526819939406,-1.3232487120310719,-0.3237756446783554,-0.471302155269236,-0.9812088834856775,0.06624331600225977,0.0846519922036011,-0.5146374427323911,-1.0316061132826644,0.7979678150313219,-0.16251400074754818,0.5326129525524724,-0.30320435577832683,0.75252729309868,-0.9315555215226238,-0.10391188008073553,-0.4285051553274654,-0.5585258554562905,0.9018467708360485,-0.10391188008073553,1.6659669752722266,-0.04627372815783212,2.5269406716164067,3.7489696574923244,-0.10391188008073553,2.5364613381868493
| 3,447
|
Microbody membrane
| 12
| 26
| 2.470058
| 0.013509
|
O15228,P56589,Q9BY49,Q9NP80,O75381,Q9NR77,Q15067,P51648,Q6IAN0,O43808,Q8WVX9,P28288
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
567,351,385,398,491,18,663,29,505,347,541,287
|
919,1003,567,347,1965,491,842,2490,287,2814,788,682,29,1340,351,663,505,1488,1112,541,1753,385,398,18,2357,1768
|
0.2461611801381823,0.19313737866175912,0.6285012150671874,1.115012567814737,-0.24221132899251827,0.7828838337881776,0.3156532797160656,-0.471302155269236,1.342624187693322,-0.6480246355463081,0.3668988157742944,0.46724146702283265,3.3348312629722443,0.010434058495094673,1.1011786466586961,0.500075572431892,0.75252729309868,-0.04627372815783212,0.13930990831158938,0.6755089741541659,-0.14287070187912912,1.0028619724328278,0.9742827906130651,3.642085390164092,-0.3862322082359554,-0.14287070187912912
| 3,447
|
Electron transfer activity
| 20
| 55
| 2.467214
| 0.013617
|
O75306,P14406,O43175,O43676,Q9UDW1,P21912,P03886,P16435,Q99643,O75438,O96000,O95168,Q9Y6M9,Q9P0J0,P13073,P27338,P51970,P00403,Q16134,P20674
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
382,1,512,8,14,270,146,275,432,181,568,453,86,87,89,221,484,245,504,508
|
2182,1597,512,1600,8,2272,840,1327,382,706,181,2117,453,3383,2390,568,2583,245,146,1128,2972,578,2812,879,2585,89,3230,1,1718,275,3336,508,270,2632,2024,221,3345,2194,2495,1009,3171,1196,2595,3214,484,1781,632,504,3142,1631,2409,432,87,14,86
|
-0.3237756446783554,-0.10391188008073553,0.7219155083838219,-0.10391188008073553,3.873674680039861,-0.36528796300450794,0.3156532797160656,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,-0.5146374427323911,1.5694020954564156,2.1257159606954366,0.12118423630495645,-0.7632999174742385,0.6126954261187706,-0.6480246355463081,0.2810765284904778,-0.5146374427323911,2.517396848234407,-1.0570912841778808,4.313649129144161,-0.14287070187912912,1.3942178014247664,-1.2956536049018468,0.7372535957044981,1.40700578874686,-0.5365115565809986,-0.2624237136765148,1.7015526819939406,-1.3232487120310719,-0.3237756446783554,-0.471302155269236,0.19313737866175912,-0.9812088834856775,0.0846519922036011,-0.5146374427323911,-1.0316061132826644,0.7979678150313219,-0.16251400074754818,0.5326129525524724,0.75252729309868,-0.9315555215226238,-0.10391188008073553,-0.4285051553274654,0.9018467708360485,2.5269406716164067,3.7489696574923244,2.5364613381868493
| 3,447
|
Lipid localization
| 26
| 82
| 2.458516
| 0.013951
|
Q14534,Q9NP80,Q99720,Q9BUR5,Q9BQE5,Q9H6V9,P28288,O43772,P07602,P30536,P08183,Q7Z3C6,O15118,Q9NZJ7,P50416,P35610,Q4KMQ2,Q9H2V7,P17900,P14174,O15260,O95674,O43808,Q14108,P04062,Q8WTV0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
130,398,142,147,22,150,287,286,166,41,299,176,186,187,316,321,323,69,198,330,88,220,347,93,97,241
|
587,3246,1003,186,88,286,347,605,2746,865,842,220,2668,3435,97,2121,1329,166,3428,1714,299,1558,844,330,198,1290,2441,395,287,41,882,2814,1231,321,805,1132,316,557,3347,524,3006,1389,2206,1926,3362,1683,93,130,323,1446,559,1450,176,872,3385,1492,241,3376,971,142,22,2734,147,2348,3350,2522,69,2003,722,150,398,2737,2229,187,2529,2775,575,1032,799,1218,1768,1186
|
0.5968202922124238,-1.0827717031939503,0.19313737866175912,1.8633490032538682,2.517396848234407,1.342624187693322,1.115012567814737,0.5648593382990243,-0.6029828692428588,0.29840678518812824,0.3156532797160656,1.7015526819939406,-0.5585258554562905,-2.89120220745136,2.4693260750464634,-0.30320435577832683,0.010434058495094673,2.007685211650335,-2.333607799065281,-0.14287070187912912,1.2771132720400578,-0.08459375235902318,0.3156532797160656,1.1698368489882653,1.794848233650915,0.029135457235295485,-0.44983727276622243,0.9742827906130651,1.342624187693322,3.0360255403392498,0.2810765284904778,-0.6480246355463081,0.06624331600225977,1.1969478078787075,0.349898446135214,0.12118423630495645,1.2238621747785425,0.6442383099094389,-1.3232487120310719,0.7065124420438686,-0.7868309696564781,-0.008367163295788871,-0.3237756446783554,-0.2221155959941241,-1.3791392568827447,-0.12333709979746053,2.4886252124811126,2.1886057148305667,1.1969478078787075,-0.027269365976897105,0.6442383099094389,-0.027269365976897105,1.9306423672509032,0.29840678518812824,-1.4938226351232837,-0.04627372815783212,1.6059037631322783,-1.4359917276919325,0.2285742779294462,2.1362689307517044,3.4575058283936557,-0.5806822940457038,2.1045230542075872,-0.3862322082359554,-1.3232487120310719,-0.471302155269236,2.749311957797667,-0.24221132899251827,0.4341047300866308,2.0832130390930095,0.9742827906130651,-0.5806822940457038,-0.3237756446783554,1.8633490032538682,-0.471302155269236,-0.6029828692428588,0.6285012150671874,0.19313737866175912,0.3668988157742944,0.0846519922036011,-0.14287070187912912,0.10296527861463395
| 3,447
|
Alzheimers disease and mirna effects
| 16
| 94
| 2.447201
| 0.014397
|
Q9BVA1,Q9NQC3,P49721,P42574,P07437,Q9BUF5,P16615,P68371,P04350,P45880,P12235,Q9Y277,Q13885,O95197,P12236,P21796
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
34,35,162,229,43,107,136,78,47,16,208,82,52,23,183,27
|
1961,2386,2945,838,863,2780,2917,839,727,23,47,1040,1970,258,1774,1712,43,1971,1869,208,183,2021,136,2786,2491,2891,1775,980,27,3189,1871,1613,2443,2444,949,1614,2848,522,1673,1517,1291,882,1616,1430,2923,732,229,3094,16,765,710,619,2078,162,1047,2202,1075,2203,1572,2204,2288,1077,78,1779,1297,1886,2085,3362,1827,1780,1103,1578,1580,52,2142,2377,793,2506,966,689,411,2567,2310,1752,2962,107,34,1456,35,460,2805,915,82,3245
|
-0.24221132899251827,-0.4285051553274654,-0.7399306553991354,0.3156532797160656,0.29840678518812824,-0.6254296213866243,-0.7167208001281143,0.3156532797160656,0.4174209793635682,3.4195663235378624,2.9427278149247016,0.17528547971368946,-0.24221132899251827,1.4702992943855286,-0.16251400074754818,-0.14287070187912912,3.002350444101246,-0.24221132899251827,-0.20213507046424417,1.7717381563510717,1.8859120022561358,-0.2624237136765148,2.1572887559147627,-0.6254296213866243,-0.471302155269236,-0.6936680218939302,-0.16251400074754818,0.21089999179645574,3.3503698232892996,-1.0063130127151403,-0.20213507046424417,-0.10391188008073553,-0.44983727276622243,-0.44983727276622243,0.2285742779294462,-0.10391188008073553,-0.6707700428550947,0.7065124420438686,-0.12333709979746053,-0.06538144972417397,0.029135457235295485,0.2810765284904778,-0.10391188008073553,-0.027269365976897105,-0.7167208001281143,0.4174209793635682,1.6420560339548476,-0.8826227148684676,3.6994359897329634,0.3838188193188344,0.4341047300866308,0.5487721681964972,-0.28275422227728697,2.040236030803411,0.17528547971368946,-0.3237756446783554,0.15734332005004562,-0.3237756446783554,-0.08459375235902318,-0.3237756446783554,-0.36528796300450794,0.15734332005004562,2.685738533107751,-0.16251400074754818,0.029135457235295485,-0.20213507046424417,-0.28275422227728697,-1.3791392568827447,-0.1822683354853108,-0.16251400074754818,0.13930990831158938,-0.08459375235902318,-0.08459375235902318,2.890903968218817,-0.30320435577832683,-0.40730404219216754,0.3668988157742944,-0.471302155269236,0.2285742779294462,0.46724146702283265,0.9599094643624182,-0.49290160023430213,-0.36528796300450794,-0.14287070187912912,-0.7399306553991354,2.381281697129018,3.200287370541324,-0.027269365976897105,3.1922316667835537,0.8428492678399792,-0.6254296213866243,0.2636616261122957,2.6118073444066714,-1.0570912841778808
| 3,447
|
mitochondrial carrier protein
| 8
| 9
| 2.44686
| 0.014411
|
Q9Y6C9,Q70HW3,Q6NUK1,Q9BSK2,Q86VD7,Q9HC21,Q6KCM7,Q9NZJ7
|
Functions
|
Panther Protein class
|
panther_protein_class
|
37,72,425,76,332,143,306,187
|
450,306,425,72,332,76,143,187,37
|
0.8576880629169049,1.2505830026120932,0.9164488273167519,2.722191252729754,1.1698368489882653,2.6948832866620145,2.1362689307517044,1.8633490032538682,3.1760717839026786
| 3,447
|
Passive transmembrane transporter activity
| 15
| 35
| 2.446102
| 0.014441
|
P51790,Q4KMQ2,P0CG08,Q9BVC6,P45880,P61619,P24539,P56385,Q9Y277,O75964,Q99797,O96008,P21796,P56134,Q9UM00
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
448,323,514,370,16,336,209,337,82,21,502,464,27,405,285
|
1909,2748,21,464,1163,1329,2541,514,27,209,2847,1617,2130,788,16,3406,448,749,1677,405,337,336,1779,2142,323,2762,966,1143,2222,502,370,563,285,82,3273
|
-0.2221155959941241,-0.6029828692428588,3.5692505459608204,0.8279499860422683,0.10296527861463395,0.010434058495094673,-0.49290160023430213,0.7219155083838219,3.3503698232892996,1.7601302536193415,-0.6707700428550947,-0.10391188008073553,-0.30320435577832683,0.3668988157742944,3.6994359897329634,-1.673164747906431,0.8576880629169049,0.4006592727447067,-0.12333709979746053,0.9599094643624182,1.1425261705350076,1.156206673163405,-0.16251400074754818,-0.30320435577832683,1.1969478078787075,-0.6029828692428588,0.2285742779294462,0.12118423630495645,-0.3237756446783554,0.7677371814906225,1.059363369451296,0.6442383099094389,1.3555894999858193,2.6118073444066714,-1.1086506296557357
| 3,447
|
Golgi cisterna membrane
| 11
| 20
| 2.440837
| 0.014653
|
O00461,P0CG08,Q96L58,Q9P2E5,Q8WVQ1,Q10472,Q10713,P98194,P51572,Q15363,Q9H4A6
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
36,514,390,460,457,305,344,215,404,222,251
|
36,514,404,215,3217,2292,1575,305,344,222,1349,1994,457,624,390,1797,251,460,1764,2177
|
3.184159827888789,0.7219155083838219,0.9599094643624182,1.7133407362411066,-1.0316061132826644,-0.36528796300450794,-0.08459375235902318,1.2505830026120932,1.1287949380852866,1.7015526819939406,0.010434058495094673,-0.24221132899251827,0.8428492678399792,0.5487721681964972,0.9886001370636728,-0.16251400074754818,1.5325436558776693,0.8428492678399792,-0.14287070187912912,-0.30320435577832683
| 3,447
|
Proton transmembrane transport
| 15
| 42
| 2.433835
| 0.01494
|
P51790,Q00325,P05141,Q99623,Q9UDW1,Q96ES6,P12235,P24539,P56385,O75964,P00403,P13073,P05023,P56134,Q13423
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
448,450,258,271,14,431,208,209,337,21,245,89,309,405,255
|
1597,666,1326,1327,2748,21,245,1128,309,258,1163,578,879,208,89,508,2492,3361,209,2847,1291,1009,1617,2924,2130,1196,3406,448,405,337,1076,450,255,431,2688,271,3061,1501,14,1763,1253,1032
|
-0.10391188008073553,0.4836959753352828,0.010434058495094673,0.010434058495094673,-0.6029828692428588,3.5692505459608204,1.5694020954564156,0.12118423630495645,1.237246593120908,1.4702992943855286,0.10296527861463395,0.6126954261187706,0.2810765284904778,1.7717381563510717,2.517396848234407,0.7372535957044981,-0.471302155269236,-1.3791392568827447,1.7601302536193415,-0.6707700428550947,0.029135457235295485,0.19313737866175912,-0.10391188008073553,-0.7167208001281143,-0.30320435577832683,0.0846519922036011,-1.673164747906431,0.8576880629169049,0.9599094643624182,1.1425261705350076,0.15734332005004562,0.8576880629169049,1.4953208273418972,0.9018467708360485,-0.5585258554562905,1.40700578874686,-0.8343882553406996,-0.04627372815783212,3.7489696574923244,-0.14287070187912912,0.06624331600225977,0.19313737866175912
| 3,447
|
Cholesterol metabolism
| 16
| 27
| 2.429835
| 0.015106
|
Q14739,P35610,P04062,Q16850,Q15800,Q15392,O15118,P37268,Q9UBM7,P61916,O76062,Q15125,O94905,P14324,O75477,P54646
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
128,321,97,164,7,40,186,199,400,557,115,84,463,402,476,375
|
186,476,115,463,1161,3435,97,402,2846,321,199,750,375,557,3006,3314,1683,2375,128,84,2860,40,581,7,164,400,2775
|
1.8633490032538682,0.8129896825372822,2.2912039487046916,0.8279499860422683,0.10296527861463395,-2.89120220745136,2.4693260750464634,0.9599094643624182,-0.6707700428550947,1.1969478078787075,1.794848233650915,0.4006592727447067,1.0312209548801738,0.6442383099094389,-0.7868309696564781,-1.214219613160026,-0.12333709979746053,-0.40730404219216754,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,2.0294163563584418,0.9742827906130651,-0.6029828692428588
| 3,447
|
golgi
| 24
| 61
| 2.427306
| 0.015211
|
Q9Y3E0,Q15907,Q01968,Q9Y487,Q9UM00,O14579,Q5VW38,O14745,Q8IXU6,Q7Z3C6,Q5R372,Q9H0U4,Q13190,Q15437,P61026,Q9NR31,Q15904,P61923,P49755,O15258,P62820,O15127,Q9NTJ5,Q9UBF8
|
Localization
|
OpenCell Localization
|
opencell_localization
|
393,141,791,149,285,780,158,666,295,176,702,452,322,715,580,206,592,711,343,219,734,218,371,637
|
780,666,1810,218,219,1375,1913,2626,2019,2125,1290,1337,2924,2025,343,3305,1521,2453,2030,953,580,711,734,1269,791,1391,2292,322,1397,2040,715,592,141,702,158,3316,962,176,295,2415,1241,1994,1691,1145,2348,452,837,1853,206,371,2529,1706,2318,637,285,1155,393,1807,149,1063,1157
|
0.3668988157742944,0.4836959753352828,-0.1822683354853108,1.7015526819939406,1.7015526819939406,-0.008367163295788871,-0.2221155959941241,-0.5365115565809986,-0.2624237136765148,-0.30320435577832683,0.029135457235295485,0.010434058495094673,-0.7167208001281143,-0.2624237136765148,1.1287949380852866,-1.1875123306433095,-0.06538144972417397,-0.44983727276622243,-0.2624237136765148,0.2285742779294462,0.6126954261187706,0.4341047300866308,0.4174209793635682,0.04773817048517167,0.3668988157742944,-0.008367163295788871,-0.36528796300450794,1.1969478078787075,-0.008367163295788871,-0.2624237136765148,0.4341047300866308,0.5968202922124238,2.1362689307517044,0.45071130368158374,2.051025353873208,-1.214219613160026,0.2285742779294462,1.9306423672509032,1.3034558937486695,-0.4285051553274654,0.06624331600225977,-0.24221132899251827,-0.12333709979746053,0.12118423630495645,-0.3862322082359554,0.8576880629169049,0.3328168814905901,-0.1822683354853108,1.7833107392720506,1.059363369451296,-0.471302155269236,-0.12333709979746053,-0.36528796300450794,0.5326129525524724,1.3555894999858193,0.12118423630495645,0.9886001370636728,-0.16251400074754818,2.0938827725307765,0.17528547971368946,0.12118423630495645
| 3,447
|
Vacuole organization
| 22
| 55
| 2.422032
| 0.015434
|
Q15042,P16615,O14773,Q12768,Q9UNZ2,Q9H270,Q6IAA8,Q7Z3C6,P11117,O95817,O95140,Q8N511,Q9H0U4,Q9Y2L5,P20339,Q16706,P50897,P54802,Q6PHR2,Q14108,P04062,O75503
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
649,136,145,416,290,562,559,176,554,438,437,63,452,586,579,593,77,335,470,93,97,492
|
2066,145,1064,492,437,1867,438,97,1329,3428,947,554,136,579,732,1474,77,1168,335,3120,1169,734,416,93,649,850,593,559,470,176,3325,872,63,1053,2611,1994,1213,675,1901,1057,452,836,562,837,1116,2229,2883,1218,290,1184,586,1155,2536,2115,3245
|
-0.28275422227728697,2.1257159606954366,0.15734332005004562,0.7828838337881776,0.8871862971088242,-0.20213507046424417,0.8871862971088242,2.4693260750464634,0.010434058495094673,-2.333607799065281,0.2285742779294462,0.6442383099094389,2.1572887559147627,0.6126954261187706,0.4174209793635682,-0.04627372815783212,2.685738533107751,0.10296527861463395,1.156206673163405,-0.9070004618348723,0.10296527861463395,0.4174209793635682,0.9454796834826562,2.4886252124811126,0.5163809909451085,0.3156532797160656,0.5968202922124238,0.6442383099094389,0.8279499860422683,1.9306423672509032,-1.241143026979425,0.29840678518812824,2.776248153122407,0.17528547971368946,-0.5146374427323911,-0.24221132899251827,0.0846519922036011,0.4836959753352828,-0.20213507046424417,0.17528547971368946,0.8576880629169049,0.3328168814905901,0.6442383099094389,0.3328168814905901,0.13930990831158938,-0.3237756446783554,-0.6707700428550947,0.0846519922036011,1.3296137106483024,0.10296527861463395,0.6126954261187706,0.12118423630495645,-0.471302155269236,-0.28275422227728697,-1.0570912841778808
| 3,447
|
Secondary alcohol metabolic process
| 20
| 45
| 2.416869
| 0.015655
|
Q14739,Q14534,Q15800,Q9UBM7,P16435,Q9BQE5,P14324,Q16850,Q15392,O15118,P35610,P37268,Q15125,O94905,P04062,O75845,Q06520,Q8WTV0,O76062,P54646
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
128,130,7,400,275,22,402,164,40,186,321,199,84,463,97,357,238,241,115,375
|
186,840,476,357,3304,115,463,1161,3435,97,1970,2246,402,275,2846,321,199,1978,1621,3437,2707,3003,1475,750,375,557,3006,3314,238,1683,2375,130,128,1932,84,2860,40,581,7,164,241,3037,22,400,2775
|
1.8633490032538682,0.3156532797160656,0.8129896825372822,1.0872927564021313,-1.1875123306433095,2.2912039487046916,0.8279499860422683,0.10296527861463395,-2.89120220745136,2.4693260750464634,-0.24221132899251827,-0.3444696497798871,0.9599094643624182,1.3942178014247664,-0.6707700428550947,1.1969478078787075,1.794848233650915,-0.24221132899251827,-0.10391188008073553,-3.1289721752401443,-0.5806822940457038,-0.7868309696564781,-0.04627372815783212,0.4006592727447067,1.0312209548801738,0.6442383099094389,-0.7868309696564781,-1.214219613160026,1.6179929845170453,-0.12333709979746053,-0.40730404219216754,2.1886057148305667,2.2196712726732395,-0.2221155959941241,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,2.0294163563584418,1.6059037631322783,-0.8105262504581725,3.4575058283936557,0.9742827906130651,-0.6029828692428588
| 3,447
|
Action tremor
| 10
| 57
| 2.416085
| 0.015688
|
Q9H6K4,P07602,Q99720,P04350,O14773,P03886,Q9NR77,Q6PJG6,Q9NZJ7,Q14108
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
67,166,142,47,145,146,18,211,187,93
|
2810,145,1095,2621,531,763,382,707,437,2626,146,1128,3410,47,166,1714,785,1194,2891,2023,2441,1917,2197,1338,661,2976,1520,2132,1199,1268,1438,1887,93,671,2041,1742,2339,3176,211,813,216,2610,2688,2770,142,67,1503,18,3341,2427,616,187,391,1366,1860,2180,2360
|
-0.6480246355463081,2.1257159606954366,0.13930990831158938,-0.5365115565809986,0.6910437992675935,0.3838188193188344,1.0028619724328278,0.4341047300866308,0.8871862971088242,-0.5365115565809986,2.1257159606954366,0.12118423630495645,-1.7348868279040783,2.9427278149247016,2.007685211650335,-0.14287070187912912,0.3668988157742944,0.0846519922036011,-0.6936680218939302,-0.2624237136765148,-0.44983727276622243,-0.2221155959941241,-0.3237756446783554,0.010434058495094673,0.500075572431892,-0.7632999174742385,-0.06538144972417397,-0.30320435577832683,0.0846519922036011,0.04773817048517167,-0.027269365976897105,-0.20213507046424417,2.4886252124811126,0.4836959753352828,-0.2624237136765148,-0.14287070187912912,-0.3862322082359554,-0.9812088834856775,1.7368075518613622,0.349898446135214,1.7133407362411066,-0.5146374427323911,-0.5585258554562905,-0.6029828692428588,2.1362689307517044,2.7583110565843194,-0.04627372815783212,3.642085390164092,-1.2956536049018468,-0.4285051553274654,0.5648593382990243,1.8633490032538682,0.9886001370636728,0.010434058495094673,-0.1822683354853108,-0.30320435577832683,-0.3862322082359554
| 3,447
|
Mitochondrial calcium ion transport
| 7
| 16
| 2.415596
| 0.015709
|
O95202,Q99623,P45880,Q9Y277,Q9H300,Q10713,P21796
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
169,271,16,82,307,344,27
|
2971,169,27,2496,16,344,966,363,2419,1951,271,1540,307,1032,82,2180
|
-0.7632999174742385,1.9858304188448097,3.3503698232892996,-0.471302155269236,3.6994359897329634,1.1287949380852866,0.2285742779294462,1.0733544735925842,-0.4285051553274654,-0.2221155959941241,1.40700578874686,-0.06538144972417397,1.2505830026120932,0.19313737866175912,2.6118073444066714,-0.30320435577832683
| 3,447
|
Regulation of ph
| 9
| 20
| 2.407579
| 0.016059
|
P51790,Q92544,P0CG08,Q9Y6M7,P50897,Q93050,O75503,Q9Y487,Q8N511
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
448,223,514,530,77,175,492,149,63
|
492,1163,514,949,1517,77,1168,448,1076,2457,592,63,223,175,1213,1763,1253,149,3273,530
|
0.7828838337881776,0.10296527861463395,0.7219155083838219,0.2285742779294462,-0.06538144972417397,2.685738533107751,0.10296527861463395,0.8576880629169049,0.15734332005004562,-0.44983727276622243,0.5968202922124238,2.776248153122407,1.6897278697989968,1.9417437419205628,0.0846519922036011,-0.14287070187912912,0.06624331600225977,2.0938827725307765,-1.1086506296557357,0.7065124420438686
| 3,447
|
Regulation of cellular ph
| 9
| 20
| 2.407579
| 0.016059
|
P51790,Q92544,P0CG08,Q9Y6M7,P50897,Q93050,O75503,Q9Y487,Q8N511
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
448,223,514,530,77,175,492,149,63
|
492,1163,514,949,1517,77,1168,448,1076,2457,592,63,223,175,1213,1763,1253,149,3273,530
|
0.7828838337881776,0.10296527861463395,0.7219155083838219,0.2285742779294462,-0.06538144972417397,2.685738533107751,0.10296527861463395,0.8576880629169049,0.15734332005004562,-0.44983727276622243,0.5968202922124238,2.776248153122407,1.6897278697989968,1.9417437419205628,0.0846519922036011,-0.14287070187912912,0.06624331600225977,2.0938827725307765,-1.1086506296557357,0.7065124420438686
| 3,447
|
Metapathway biotransformation phase i and ii
| 7
| 22
| 2.40689
| 0.016089
|
Q16850,Q06520,P21964,Q6UW02,P07099,Q99735,Q7LGA3
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
164,238,83,116,57,252,126
|
361,1600,2583,57,2545,1718,2892,83,2976,1073,2033,2370,238,164,116,126,673,2729,252,1455,2772,1122
|
1.0733544735925842,-0.10391188008073553,-0.5146374427323911,2.8471962253506646,-0.49290160023430213,-0.14287070187912912,-0.6936680218939302,2.574314841840362,-0.7632999174742385,0.15734332005004562,-0.2624237136765148,-0.40730404219216754,1.6179929845170453,2.0294163563584418,2.2912039487046916,2.229971341354025,0.4836959753352828,-0.5806822940457038,1.5201769173547421,-0.027269365976897105,-0.6029828692428588,0.13930990831158938
| 3,447
|
Cholesterol biosynthesis
| 9
| 17
| 2.406794
| 0.016093
|
Q14739,Q16850,P37268,Q15392,Q15800,Q9UBM7,O76062,Q15125,P54646
|
Processes and pathways
|
Protein Atlas Biological process
|
protein_atlas_biological_process
|
128,164,199,40,7,400,115,84,375
|
115,1161,402,199,750,375,3314,1683,2375,128,84,2860,40,581,7,164,400
|
2.2912039487046916,0.10296527861463395,0.9599094643624182,1.794848233650915,0.4006592727447067,1.0312209548801738,-1.214219613160026,-0.12333709979746053,-0.40730404219216754,2.2196712726732395,2.555433683915995,-0.6707700428550947,3.0610973203490204,0.6126954261187706,3.9211731425024707,2.0294163563584418,0.9742827906130651
| 3,447
|
Organelle disassembly
| 16
| 51
| 2.401711
| 0.016319
|
P04062,Q13190,Q709C8,P05141,P52789,Q9BWH2,P30536,Q99623,Q16543,P12235,Q7Z3C6,Q9H300,O00429,O95140,P21796,P27544
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
97,322,583,258,612,227,41,271,469,208,176,307,588,437,27,61
|
898,588,1864,1223,437,1867,97,2843,258,1006,208,1775,27,61,41,1616,2755,2198,1383,1474,612,2369,3120,902,2085,2292,322,2956,469,583,1531,176,2153,1402,1691,3102,970,2688,271,1849,795,227,307,862,1116,1414,638,1860,1768,2115,3245
|
0.2636616261122957,0.5968202922124238,-0.20213507046424417,0.06624331600225977,0.8871862971088242,-0.20213507046424417,2.4693260750464634,-0.6707700428550947,1.4702992943855286,0.19313737866175912,1.7717381563510717,-0.16251400074754818,3.3503698232892996,2.7851863493439573,3.0360255403392498,-0.10391188008073553,-0.6029828692428588,-0.3237756446783554,-0.008367163295788871,-0.04627372815783212,0.5648593382990243,-0.40730404219216754,-0.9070004618348723,0.2636616261122957,-0.28275422227728697,-0.36528796300450794,1.1969478078787075,-0.7399306553991354,0.8279499860422683,0.6126954261187706,-0.06538144972417397,1.9306423672509032,-0.30320435577832683,-0.008367163295788871,-0.12333709979746053,-0.8826227148684676,0.2285742779294462,-0.5585258554562905,1.40700578874686,-0.1822683354853108,0.3668988157742944,1.6540303882823562,1.2505830026120932,0.3156532797160656,0.13930990831158938,-0.008367163295788871,0.5326129525524724,-0.1822683354853108,-0.14287070187912912,-0.28275422227728697,-1.0570912841778808
| 3,447
|
Cis golgi network
| 10
| 18
| 2.398844
| 0.016447
|
P24390,O95249,O00461,Q9Y3A6,O43731,Q9UNK9,Q16706,P49755,Q8TBA6,P98194
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,66,36,422,6,565,593,343,247,215
|
36,1601,6,66,0,827,343,215,2292,1526,593,3325,247,1994,1691,624,565,422
|
3.184159827888789,-0.10391188008073553,3.9547704783957736,2.7583110565843194,4.529155521859711,0.3328168814905901,1.1287949380852866,1.7133407362411066,-0.36528796300450794,-0.06538144972417397,0.5968202922124238,-1.241143026979425,1.5571559613224766,-0.24221132899251827,-0.12333709979746053,0.5487721681964972,0.6442383099094389,0.9309929669262402
| 3,447
|
Positive regulation of mitochondrion organization
| 6
| 21
| 2.398258
| 0.016473
|
P05141,Q96A26,P12235,Q8N2A8,P21796,P27544
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
258,45,208,152,27,61
|
588,1372,2538,2843,258,3372,208,27,61,1291,2590,2198,152,966,45,1309,1057,2688,301,1414,1768
|
0.5968202922124238,-0.008367163295788871,-0.49290160023430213,-0.6707700428550947,1.4702992943855286,-1.4359917276919325,1.7717381563510717,3.3503698232892996,2.7851863493439573,0.029135457235295485,-0.5146374427323911,-0.3237756446783554,2.0725136772787915,0.2285742779294462,2.9598538605341833,0.029135457235295485,0.17528547971368946,-0.5585258554562905,1.2771132720400578,-0.008367163295788871,-0.14287070187912912
| 3,447
|
Oxidoreductase complex
| 19
| 61
| 2.397739
| 0.016497
|
O75306,O43169,O43676,Q9UDW1,P21912,P03886,O14949,Q99643,Q96CU9,O75438,O96000,P13674,Q9Y276,Q86Y39,O95168,Q9Y6M9,Q9P0J0,P51970,P07237
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
382,2,8,14,270,146,24,432,180,181,568,569,461,71,453,86,87,484,236
|
2182,3274,1597,24,2,8,2272,840,1327,382,706,181,2117,453,3383,2390,568,2750,1161,146,1128,1421,236,2328,578,1422,3290,2844,2753,569,3230,1228,3336,270,981,2024,2442,3345,2495,982,1009,2893,3171,1232,1196,3214,3003,484,2456,1933,3142,1631,2213,71,2649,180,432,87,14,461,86
|
-0.3237756446783554,-1.1347314072680073,-0.10391188008073553,3.411935775289236,4.307502880587425,3.873674680039861,-0.36528796300450794,0.3156532797160656,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.6285012150671874,-0.6029828692428588,0.10296527861463395,2.1257159606954366,0.12118423630495645,-0.027269365976897105,1.6179929845170453,-0.3862322082359554,0.6126954261187706,-0.027269365976897105,-1.161017467090014,-0.6707700428550947,-0.6029828692428588,0.6285012150671874,-1.0570912841778808,0.06624331600225977,-1.2956536049018468,1.40700578874686,0.21089999179645574,-0.2624237136765148,-0.44983727276622243,-1.3232487120310719,-0.471302155269236,0.21089999179645574,0.19313737866175912,-0.6936680218939302,-0.9812088834856775,0.06624331600225977,0.0846519922036011,-1.0316061132826644,-0.7868309696564781,0.7979678150313219,-0.44983727276622243,-0.2221155959941241,-0.9315555215226238,-0.10391188008073553,-0.3237756446783554,2.7312521573765434,-0.5365115565809986,1.9195087103543416,0.9018467708360485,2.5269406716164067,3.7489696574923244,0.8428492678399792,2.5364613381868493
| 3,447
|
Lipid droplet
| 12
| 31
| 2.397225
| 0.01652
|
Q15738,Q07065,Q8NBX0,Q8NF37,O60664,Q15042,Q99720,Q8NBQ5,Q9H6V9,P51572,Q01105,O43760
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
581,163,389,264,605,649,142,373,150,404,539,124
|
2841,124,1965,605,842,1161,1040,1329,1621,1622,1168,404,2369,1980,539,163,649,581,1446,1401,373,389,264,1691,992,142,722,150,1088,2575,1186
|
-0.6707700428550947,2.2504897475867147,-0.24221132899251827,0.5648593382990243,0.3156532797160656,0.10296527861463395,0.17528547971368946,0.010434058495094673,-0.10391188008073553,-0.10391188008073553,0.10296527861463395,0.9599094643624182,-0.40730404219216754,-0.24221132899251827,0.6755089741541659,2.040236030803411,0.5163809909451085,0.6126954261187706,-0.027269365976897105,-0.008367163295788871,1.045319009782404,0.9886001370636728,1.445109921894803,-0.12333709979746053,0.21089999179645574,2.1362689307517044,0.4341047300866308,2.0832130390930095,0.15734332005004562,-0.49290160023430213,0.10296527861463395
| 3,447
|
Golgi associated vesicle
| 6
| 35
| 2.396318
| 0.016561
|
P24390,O43731,Q9Y3B3,O43493,Q15363,Q8N511
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
0,6,234,243,222,63
|
780,243,6,1549,1224,1970,2019,3117,0,1337,1567,618,343,3026,2498,1521,2898,1169,711,1626,1269,791,222,63,1452,1994,1797,2001,1029,1090,1706,2318,1958,234,1157
|
0.3668988157742944,1.593775721781699,3.9547704783957736,-0.08459375235902318,0.06624331600225977,-0.24221132899251827,-0.2624237136765148,-0.9070004618348723,4.529155521859711,0.010434058495094673,-0.08459375235902318,0.5487721681964972,1.1287949380852866,-0.8105262504581725,-0.471302155269236,-0.06538144972417397,-0.6936680218939302,0.10296527861463395,0.4341047300866308,-0.10391188008073553,0.04773817048517167,0.3668988157742944,1.7015526819939406,2.776248153122407,-0.027269365976897105,-0.24221132899251827,-0.16251400074754818,-0.24221132899251827,0.19313737866175912,0.15734332005004562,-0.12333709979746053,-0.36528796300450794,-0.2221155959941241,1.6300436532822637,0.12118423630495645
| 3,447
|
Poor eye contact
| 9
| 39
| 2.394919
| 0.016624
|
Q86Y39,O43676,Q5XKP0,Q15907,Q9UHX1,P03886,Q96CU9,Q9Y6M9,Q9P0J0
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
71,8,137,141,110,146,180,86,87
|
2182,8,1327,382,706,2117,1669,1968,568,146,3336,3345,1429,3214,3080,1233,1199,1438,1887,1575,2335,141,1585,2821,137,71,874,180,875,1495,2051,3388,2875,193,2834,3039,87,110,86
|
-0.3237756446783554,3.873674680039861,0.010434058495094673,1.0028619724328278,0.4341047300866308,-0.30320435577832683,-0.12333709979746053,-0.24221132899251827,0.6285012150671874,2.1257159606954366,-1.2956536049018468,-1.3232487120310719,-0.027269365976897105,-1.0316061132826644,-0.8584195385239018,0.06624331600225977,0.0846519922036011,-0.027269365976897105,-0.20213507046424417,-0.08459375235902318,-0.3862322082359554,2.1362689307517044,-0.08459375235902318,-0.6480246355463081,2.1572887559147627,2.7312521573765434,0.29840678518812824,1.9195087103543416,0.29840678518812824,-0.04627372815783212,-0.2624237136765148,-1.4938226351232837,-0.6707700428550947,1.8292524636194953,-0.6480246355463081,-0.8105262504581725,2.5269406716164067,2.3415041854178815,2.5364613381868493
| 3,447
|
Cytochrome complex
| 7
| 16
| 2.393113
| 0.016706
|
P14406,Q9Y276,Q9UDW1,P00403,O14949,P13073,P20674
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
1,461,14,245,24,89,508
|
1597,24,245,578,802,879,89,1,1228,922,508,981,1009,1196,14,461
|
-0.10391188008073553,3.411935775289236,1.5694020954564156,0.6126954261187706,0.349898446135214,0.2810765284904778,2.517396848234407,4.313649129144161,0.06624331600225977,0.2461611801381823,0.7372535957044981,0.21089999179645574,0.19313737866175912,0.0846519922036011,3.7489696574923244,0.8428492678399792
| 3,447
|
Macromolecule transmembrane transporter activity
| 8
| 12
| 2.390594
| 0.016821
|
Q15388,Q9NS69,O60830,Q99595,Q07820,O14925,P61619,P49755
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
353,3,4,9,300,106,336,343
|
106,4,2277,464,343,1197,336,300,353,9,3,597
|
2.391162989421182,4.1444590074269065,-0.36528796300450794,0.8279499860422683,1.1287949380852866,0.0846519922036011,1.156206673163405,1.2771132720400578,1.1011786466586961,3.8600030048314653,4.276636208213452,0.5968202922124238
| 3,447
|
Carbohydrate derivative transmembrane transporter activity
| 8
| 10
| 2.390133
| 0.016842
|
Q8TB61,P05141,Q86VD7,P12235,Q6KCM7,P12236,O43808,L0R6Q1
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,258,332,208,306,183,347,217
|
217,347,258,208,183,661,306,425,332,64
|
1.7015526819939406,1.115012567814737,1.4702992943855286,1.7717381563510717,1.8859120022561358,0.500075572431892,1.2505830026120932,0.9164488273167519,1.1698368489882653,2.776248153122407
| 3,447
|
Neuronal system
| 6
| 55
| 2.387567
| 0.01696
|
Q9BVA1,P68371,P04350,P21964,Q13885,O95197
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
34,78,47,83,52,23
|
2185,2364,1160,1005,3351,2241,23,1224,47,2122,2972,979,2074,1065,1717,1193,2244,1972,2368,3021,83,949,1517,661,2791,2897,2977,1101,1341,1102,375,790,1729,2136,1883,78,3407,700,1683,1049,929,52,2141,1483,1484,1832,3173,1084,1751,107,34,1502,3067,1092,1368
|
-0.3237756446783554,-0.40730404219216754,0.10296527861463395,0.19313737866175912,-1.35107584448545,-0.3444696497798871,3.4195663235378624,0.06624331600225977,2.9427278149247016,-0.30320435577832683,-0.7632999174742385,0.21089999179645574,-0.28275422227728697,0.15734332005004562,-0.14287070187912912,0.0846519922036011,-0.3444696497798871,-0.24221132899251827,-0.40730404219216754,-0.8105262504581725,2.574314841840362,0.2285742779294462,-0.06538144972417397,0.500075572431892,-0.6254296213866243,-0.6936680218939302,-0.7632999174742385,0.13930990831158938,0.010434058495094673,0.13930990831158938,1.0312209548801738,0.3668988157742944,-0.14287070187912912,-0.30320435577832683,-0.20213507046424417,2.685738533107751,-1.673164747906431,0.45071130368158374,-0.12333709979746053,0.17528547971368946,0.2461611801381823,2.890903968218817,-0.30320435577832683,-0.04627372815783212,-0.04627372815783212,-0.1822683354853108,-0.9812088834856775,0.15734332005004562,-0.14287070187912912,2.381281697129018,3.200287370541324,-0.04627372815783212,-0.8343882553406996,0.15734332005004562,0.010434058495094673
| 3,447
|
Nucleotide transmembrane transport
| 7
| 11
| 2.387009
| 0.016986
|
Q8TB61,P05141,Q86VD7,Q9BSK2,Q9H2D1,P12235,P12236
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
64,258,332,76,46,208,183
|
347,258,208,183,661,2762,332,64,1143,76,46
|
1.115012567814737,1.4702992943855286,1.7717381563510717,1.8859120022561358,0.500075572431892,-0.6029828692428588,1.1698368489882653,2.776248153122407,0.12118423630495645,2.6948832866620145,2.9513000228072084
| 3,447
|
Intra golgi and retrograde golgi to er traffic
| 35
| 98
| 2.380882
| 0.017271
|
P24390,O43731,Q15042,P43034,Q9BVA1,O60476,O00461,O60499,Q7Z6M1,P04350,Q10472,Q13885,Q12981,Q9UID3,Q9H0U4,O95249,Q13190,Q9P2W9,O15498,Q16706,P68371,P63167,P20645,P61923,P49755,O15260,Q15363,Q5VIR6,O60664,Q9Y3B3,Q9BUF5,Q96JB2,P48444,O43493,Q8TBA6
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
0,6,649,534,34,668,36,423,688,47,305,52,439,575,452,66,322,68,197,593,78,590,709,711,343,88,222,480,605,234,107,624,618,243,247
|
1769,36,780,88,197,1711,2841,243,6,668,423,605,1064,745,1420,2120,66,47,3117,2125,709,0,1616,1337,2025,534,2791,3153,1725,618,343,2670,1198,2498,1521,2030,1477,711,734,590,78,2402,3347,1480,888,1680,2085,1575,305,3157,439,322,1013,1831,52,1104,1784,2143,1015,649,1138,222,593,480,1304,1448,688,2412,1241,247,1142,1691,770,3162,624,3206,2936,3060,107,34,2001,1755,1456,2380,452,837,1853,1088,1956,2058,68,2318,575,1320,234,1593,1157,1187
|
-0.16251400074754818,3.184159827888789,0.3668988157742944,2.517396848234407,1.794848233650915,-0.14287070187912912,-0.6707700428550947,1.593775721781699,3.9547704783957736,0.4836959753352828,0.9164488273167519,0.5648593382990243,0.15734332005004562,0.4006592727447067,-0.027269365976897105,-0.30320435577832683,2.7583110565843194,2.9427278149247016,-0.9070004618348723,-0.30320435577832683,0.4341047300866308,4.529155521859711,-0.10391188008073553,0.010434058495094673,-0.2624237136765148,0.6910437992675935,-0.6254296213866243,-0.9562907027938861,-0.14287070187912912,0.5487721681964972,1.1287949380852866,-0.5585258554562905,0.0846519922036011,-0.471302155269236,-0.06538144972417397,-0.2624237136765148,-0.04627372815783212,0.4341047300866308,0.4174209793635682,0.5968202922124238,2.685738533107751,-0.4285051553274654,-1.3232487120310719,-0.04627372815783212,0.2810765284904778,-0.12333709979746053,-0.28275422227728697,-0.08459375235902318,1.2505830026120932,-0.9562907027938861,0.8871862971088242,1.1969478078787075,0.19313737866175912,-0.1822683354853108,2.890903968218817,0.13930990831158938,-0.16251400074754818,-0.30320435577832683,0.19313737866175912,0.5163809909451085,0.12118423630495645,1.7015526819939406,0.5968202922124238,0.8129896825372822,0.029135457235295485,-0.027269365976897105,0.46724146702283265,-0.4285051553274654,0.06624331600225977,1.5571559613224766,0.12118423630495645,-0.12333709979746053,0.3838188193188344,-0.9562907027938861,0.5487721681964972,-1.0063130127151403,-0.7167208001281143,-0.8343882553406996,2.381281697129018,3.200287370541324,-0.24221132899251827,-0.14287070187912912,-0.027269365976897105,-0.40730404219216754,0.8576880629169049,0.3328168814905901,-0.1822683354853108,0.15734332005004562,-0.2221155959941241,-0.2624237136765148,2.7583110565843194,-0.36528796300450794,0.6285012150671874,0.029135457235295485,1.6300436532822637,-0.08459375235902318,0.12118423630495645,0.10296527861463395
| 3,447
|
Exocytic vesicle
| 15
| 39
| 2.378332
| 0.017391
|
P51790,P11279,P61026,O60499,P20339,Q7L0J3,Q15907,Q9UEU0,P50897,O43760,O15400,P20020,Q15019,Q96A57,O76024
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
448,544,580,423,579,123,141,564,77,124,436,403,467,91,189
|
588,436,124,423,189,1970,2019,1971,544,403,579,747,77,1168,3026,448,2898,2638,580,1076,1522,2140,1929,2715,467,850,1832,141,1106,123,872,689,1083,91,937,2001,1956,564,1592
|
0.5968202922124238,0.8871862971088242,2.2504897475867147,0.9164488273167519,1.840651870597142,-0.24221132899251827,-0.2624237136765148,-0.24221132899251827,0.6599073521556105,0.9599094643624182,0.6126954261187706,0.4006592727447067,2.685738533107751,0.10296527861463395,-0.8105262504581725,0.8576880629169049,-0.6936680218939302,-0.5365115565809986,0.6126954261187706,0.15734332005004562,-0.06538144972417397,-0.30320435577832683,-0.2221155959941241,-0.5806822940457038,0.8279499860422683,0.3156532797160656,-0.1822683354853108,2.1362689307517044,0.13930990831158938,2.2607083952402736,0.29840678518812824,0.46724146702283265,0.15734332005004562,2.5078297460632952,0.2461611801381823,-0.24221132899251827,-0.2221155959941241,0.6442383099094389,-0.08459375235902318
| 3,447
|
Glycerophospholipid biosynthetic process
| 25
| 45
| 2.377307
| 0.01744
|
Q8NF37,Q9Y2B2,Q9BXW7,Q01968,Q8WVX9,P48651,Q9BTU6,P35790,O15228,Q9NPH0,Q99943,Q86UL3,Q10713,O95573,O95674,Q969N2,Q92643,Q96N66,Q9HBU6,Q13315,Q9NTJ5,Q9NX62,Q9UBF8,Q6IAN0,Q9HCL2
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
264,139,796,791,541,161,817,805,567,205,473,471,344,842,220,481,359,232,896,753,371,242,637,505,506
|
1189,567,2015,842,220,3213,2786,805,1567,161,1434,1389,791,1173,344,753,1394,1929,505,1210,471,2155,264,2611,541,359,481,908,232,2654,1998,2828,1752,473,817,796,896,506,205,371,242,637,1658,2532,139
|
0.0846519922036011,0.6285012150671874,-0.2624237136765148,0.3156532797160656,1.7015526819939406,-1.0316061132826644,-0.6254296213866243,0.349898446135214,-0.08459375235902318,2.040236030803411,-0.027269365976897105,-0.008367163295788871,0.3668988157742944,0.10296527861463395,1.1287949380852866,0.4006592727447067,-0.008367163295788871,-0.2221155959941241,0.75252729309868,0.0846519922036011,0.8279499860422683,-0.30320435577832683,1.445109921894803,-0.5146374427323911,0.6755089741541659,1.0872927564021313,0.8129896825372822,0.2636616261122957,1.6420560339548476,-0.5365115565809986,-0.24221132899251827,-0.6480246355463081,-0.14287070187912912,0.8279499860422683,0.349898446135214,0.3668988157742944,0.2810765284904778,0.75252729309868,1.7833107392720506,1.059363369451296,1.6059037631322783,0.5326129525524724,-0.10391188008073553,-0.471302155269236,2.1572887559147627
| 3,447
|
Calcium signaling pathway
| 8
| 19
| 2.376094
| 0.017497
|
P05141,P16615,P45880,P12235,Q9Y277,P12236,P20020,P21796
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
258,136,16,208,82,183,403,27
|
3047,258,1971,208,183,136,2368,3021,2075,403,27,483,16,1827,1780,929,2142,1763,82
|
-0.8343882553406996,1.4702992943855286,-0.24221132899251827,1.7717381563510717,1.8859120022561358,2.1572887559147627,-0.40730404219216754,-0.8105262504581725,-0.28275422227728697,0.9599094643624182,3.3503698232892996,0.7979678150313219,3.6994359897329634,-0.1822683354853108,-0.16251400074754818,0.2461611801381823,-0.30320435577832683,-0.14287070187912912,2.6118073444066714
| 3,447
|
Ferroptosis
| 6
| 25
| 2.372797
| 0.017654
|
P37268,P09601,P45880,Q9NZ45,Q9Y277,Q15366
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
199,11,16,81,82,248
|
2184,1965,1867,842,2391,2843,2629,1915,11,275,2814,199,16,2451,1070,2976,1583,248,1018,2679,719,81,3146,2357,82
|
-0.3237756446783554,-0.24221132899251827,-0.20213507046424417,0.3156532797160656,-0.4285051553274654,-0.6707700428550947,-0.5365115565809986,-0.2221155959941241,3.804859663855004,1.3942178014247664,-0.6480246355463081,1.794848233650915,3.6994359897329634,-0.44983727276622243,0.15734332005004562,-0.7632999174742385,-0.08459375235902318,1.5448699088190703,0.19313737866175912,-0.5585258554562905,0.4341047300866308,2.621124930461434,-0.9315555215226238,-0.3862322082359554,2.6118073444066714
| 3,447
|
Atp transmembrane transporter activity
| 6
| 7
| 2.361739
| 0.018189
|
P05141,Q86VD7,P12235,Q6KCM7,P12236,O43808
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
258,332,208,306,183,347
|
347,258,208,183,306,425,332
|
1.115012567814737,1.4702992943855286,1.7717381563510717,1.8859120022561358,1.2505830026120932,0.9164488273167519,1.1698368489882653
| 3,447
|
Muscle abnormality related to mitochondrial dysfunction
| 12
| 38
| 2.359329
| 0.018308
|
O75306,Q9NPL8,Q86Y39,O43676,P12235,Q9Y2R0,P03886,Q96CU9,O60313,P00403,Q9Y6M9,Q9UBX3
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
382,193,71,8,208,17,146,180,365,245,86,31
|
2182,1597,8,365,1327,382,706,2117,1191,568,245,146,1128,208,3336,3345,2790,3214,884,2710,2132,549,833,71,3144,180,2051,3061,2875,2268,398,193,3039,31,17,1369,1222,86
|
-0.3237756446783554,-0.10391188008073553,3.873674680039861,1.059363369451296,0.010434058495094673,1.0028619724328278,0.4341047300866308,-0.30320435577832683,0.0846519922036011,0.6285012150671874,1.5694020954564156,2.1257159606954366,0.12118423630495645,1.7717381563510717,-1.2956536049018468,-1.3232487120310719,-0.6254296213866243,-1.0316061132826644,0.2810765284904778,-0.5806822940457038,-0.30320435577832683,0.6599073521556105,0.3328168814905901,2.7312521573765434,-0.9315555215226238,1.9195087103543416,-0.2624237136765148,-0.8343882553406996,-0.6707700428550947,-0.3444696497798871,0.9742827906130651,1.8292524636194953,-0.8105262504581725,3.272073939679055,3.656498320463535,0.010434058495094673,0.0846519922036011,2.5364613381868493
| 3,447
|
Azurophil granule membrane
| 10
| 21
| 2.358551
| 0.018346
|
P11279,Q07065,Q9NQX7,P07602,Q9H0U3,Q8NF37,P42785,O15260,Q9NZJ7,P27105
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
544,163,195,166,325,264,230,88,187,414
|
88,1036,1865,166,947,544,414,2635,230,1622,846,163,559,264,689,2799,325,195,2737,187,2529
|
2.517396848234407,0.17528547971368946,-0.20213507046424417,2.007685211650335,0.2285742779294462,0.6599073521556105,0.9454796834826562,-0.5365115565809986,1.6420560339548476,-0.10391188008073553,0.3156532797160656,2.040236030803411,0.6442383099094389,1.445109921894803,0.46724146702283265,-0.6254296213866243,1.1969478078787075,1.8178188702918487,-0.5806822940457038,1.8633490032538682,-0.471302155269236
| 3,447
|
secondary carrier transporter
| 6
| 15
| 2.356673
| 0.018439
|
Q8TB61,P55011,Q96H78,O95202,Q96ES6,Q9UBX3
|
Functions
|
Panther Protein class
|
panther_protein_class
|
64,449,165,169,431,31
|
1003,1669,169,449,829,1450,64,431,165,1699,912,1501,31,1660,530
|
0.19313737866175912,-0.12333709979746053,1.9858304188448097,0.8576880629169049,0.3328168814905901,-0.027269365976897105,2.776248153122407,0.9018467708360485,2.018566145549778,-0.12333709979746053,0.2636616261122957,-0.04627372815783212,3.272073939679055,-0.10391188008073553,0.7065124420438686
| 3,447
|
FAD/NAD(P)-binding domain superfamily [IPR036188]
| 9
| 24
| 2.348682
| 0.01884
|
Q14534,Q9UHG3,Q6QHF9,Q9H9P8,Q96CU9,Q8NBM8,Q16134,P27338,Q6NUM9
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
130,44,111,433,180,212,504,221,350
|
1813,824,2583,1422,2846,221,2495,1560,1232,748,1821,130,504,2679,350,111,814,212,2766,180,433,44,2695,519
|
-0.1822683354853108,0.3328168814905901,-0.5146374427323911,-0.027269365976897105,-0.6707700428550947,1.7015526819939406,-0.471302155269236,-0.08459375235902318,0.06624331600225977,0.4006592727447067,-0.1822683354853108,2.1886057148305667,0.75252729309868,-0.5585258554562905,1.115012567814737,2.3314960227808297,0.349898446135214,1.7368075518613622,-0.6029828692428588,1.9195087103543416,0.9018467708360485,2.9683894129100112,-0.5585258554562905,0.7219155083838219
| 3,447
|
Protein insertion into er membrane
| 6
| 14
| 2.348602
| 0.018844
|
Q15629,Q8N4V1,Q96A33,P49069,P46379,Q9NPA0
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
33,5,178,276,179,253
|
1418,531,2387,179,276,336,1890,33,1348,5,855,178,253,626
|
-0.027269365976897105,0.6910437992675935,-0.4285051553274654,1.9195087103543416,1.3942178014247664,1.156206673163405,-0.20213507046424417,3.216350650152123,0.010434058495094673,4.040872839878629,0.3156532797160656,1.9306423672509032,1.5201769173547421,0.5487721681964972
| 3,447
|
Mitophagy
| 6
| 11
| 2.344426
| 0.019056
|
Q8IWA4,Q15388,Q9NS69,Q8N4H5,O95140,P21796
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
256,353,3,20,437,27
|
2277,437,464,1775,27,1077,353,256,20,1309,3
|
-0.36528796300450794,0.8871862971088242,0.8279499860422683,-0.16251400074754818,3.3503698232892996,0.15734332005004562,1.1011786466586961,1.4953208273418972,3.5912373381541602,0.029135457235295485,4.276636208213452
| 3,447
|
Protein transmembrane transporter activity
| 8
| 11
| 2.339822
| 0.019293
|
Q15388,Q9NS69,O60830,Q99595,Q07820,O14925,P61619,P49755
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
353,3,4,9,300,106,336,343
|
106,4,2277,464,343,336,300,353,9,3,597
|
2.391162989421182,4.1444590074269065,-0.36528796300450794,0.8279499860422683,1.1287949380852866,1.156206673163405,1.2771132720400578,1.1011786466586961,3.8600030048314653,4.276636208213452,0.5968202922124238
| 3,447
|
Intrinsic component of golgi membrane
| 7
| 10
| 2.339325
| 0.019319
|
Q8TB61,O95070,Q6ZRP7,P98194,Q9Y282,O15258,L0R6Q1
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
64,171,409,215,26,219,217
|
217,219,577,171,215,1575,409,64,429,26
|
1.7015526819939406,1.7015526819939406,0.6126954261187706,1.9638504485042398,1.7133407362411066,-0.08459375235902318,0.9599094643624182,2.776248153122407,0.9018467708360485,3.396631569290751
| 3,447
|
Recruitment of numa to mitotic centrosomes
| 6
| 37
| 2.338106
| 0.019382
|
Q9BVA1,P41208,P07437,P68371,P04350,Q13885
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
34,104,43,78,47,52
|
475,745,421,3046,47,1006,43,708,2368,3021,1264,104,534,1921,1477,1012,1824,590,78,1013,1831,52,2258,1104,1784,3124,1485,1347,1208,2215,1055,774,107,34,759,3405,2537
|
0.8129896825372822,0.4006592727447067,0.9309929669262402,-0.8343882553406996,2.9427278149247016,0.19313737866175912,3.002350444101246,0.4341047300866308,-0.40730404219216754,-0.8105262504581725,0.04773817048517167,2.401019322981899,0.6910437992675935,-0.2221155959941241,-0.04627372815783212,0.19313737866175912,-0.1822683354853108,0.5968202922124238,2.685738533107751,0.19313737866175912,-0.1822683354853108,2.890903968218817,-0.3444696497798871,0.13930990831158938,-0.16251400074754818,-0.9070004618348723,-0.04627372815783212,0.010434058495094673,0.0846519922036011,-0.3237756446783554,0.17528547971368946,0.3838188193188344,2.381281697129018,3.200287370541324,0.4006592727447067,-1.6426669410940329,-0.471302155269236
| 3,447
|
Glycerophospholipid metabolism
| 8
| 15
| 2.332631
| 0.019668
|
Q8NCC3,P48651,Q96N66,Q8NF37,O95674,Q99943,Q86UL3,Q9HCL2
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
289,161,232,264,220,473,471,506
|
567,1126,220,805,1232,161,1434,471,289,264,232,473,896,506,1658
|
0.6285012150671874,0.12118423630495645,1.7015526819939406,0.349898446135214,0.06624331600225977,2.040236030803411,-0.027269365976897105,0.8279499860422683,1.3296137106483024,1.445109921894803,1.6420560339548476,0.8279499860422683,0.2810765284904778,0.75252729309868,-0.10391188008073553
| 3,447
|
Calcium ion transport
| 13
| 61
| 2.322063
| 0.02023
|
Q4KMQ2,P98194,O95202,P30536,P16615,Q8WWC4,P61619,P61586,Q6KCM7,O76024,O75844,P21796,Q9UM00
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
323,215,169,41,136,363,336,240,306,189,58,27,285
|
588,2185,2581,2274,2971,58,189,169,2122,1969,1329,1715,2541,1915,1971,2244,2246,1227,136,2368,3021,3049,2075,403,27,483,747,41,2705,1976,1430,2198,1677,2201,1200,240,336,1824,2370,215,1779,1887,1827,3198,929,2142,3236,323,306,2340,2608,966,363,2222,2468,1540,563,1032,999,285,2180
|
0.5968202922124238,-0.3237756446783554,-0.5146374427323911,-0.36528796300450794,-0.7632999174742385,2.8295777132185935,1.840651870597142,1.9858304188448097,-0.30320435577832683,-0.24221132899251827,0.010434058495094673,-0.14287070187912912,-0.49290160023430213,-0.2221155959941241,-0.24221132899251827,-0.3444696497798871,-0.3444696497798871,0.06624331600225977,2.1572887559147627,-0.40730404219216754,-0.8105262504581725,-0.8343882553406996,-0.28275422227728697,0.9599094643624182,3.3503698232892996,0.7979678150313219,0.4006592727447067,3.0360255403392498,-0.5806822940457038,-0.24221132899251827,-0.027269365976897105,-0.3237756446783554,-0.12333709979746053,-0.3237756446783554,0.0846519922036011,1.6059037631322783,1.156206673163405,-0.1822683354853108,-0.40730404219216754,1.7133407362411066,-0.16251400074754818,-0.20213507046424417,-0.1822683354853108,-1.0063130127151403,0.2461611801381823,-0.30320435577832683,-1.0570912841778808,1.1969478078787075,1.2505830026120932,-0.3862322082359554,-0.5146374427323911,0.2285742779294462,1.0733544735925842,-0.3237756446783554,-0.44983727276622243,-0.06538144972417397,0.6442383099094389,0.19313737866175912,0.21089999179645574,1.3555894999858193,-0.30320435577832683
| 3,447
|
Huntingtons disease
| 16
| 82
| 2.321096
| 0.020282
|
P14406,P05141,P42574,O43676,Q9UDW1,P45880,P12235,Q9Y277,P24539,O75438,Q9Y6M9,P12236,O14949,P13073,P00403,P21796
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
1,258,229,8,14,16,208,82,209,181,86,183,24,89,245,27
|
2182,1286,1597,24,3112,8,2272,1327,382,706,181,2117,2748,2241,453,3383,2390,1224,568,245,3138,2843,258,1163,578,2019,802,879,208,183,89,1,1228,922,2630,1973,3336,508,27,270,981,209,2493,2847,747,3345,609,2495,1009,1617,229,2198,16,1196,3406,3214,484,2927,1341,547,3195,620,2136,1885,1269,1780,1014,1831,1104,2377,1832,3142,1631,1054,1084,2420,432,14,1320,3068,82,86
|
-0.3237756446783554,0.029135457235295485,-0.10391188008073553,3.411935775289236,-0.9070004618348723,3.873674680039861,-0.36528796300450794,0.010434058495094673,1.0028619724328278,0.4341047300866308,1.9083425678170867,-0.30320435577832683,-0.6029828692428588,-0.3444696497798871,0.8428492678399792,-1.4938226351232837,-0.4285051553274654,0.06624331600225977,0.6285012150671874,1.5694020954564156,-0.9315555215226238,-0.6707700428550947,1.4702992943855286,0.10296527861463395,0.6126954261187706,-0.2624237136765148,0.349898446135214,0.2810765284904778,1.7717381563510717,1.8859120022561358,2.517396848234407,4.313649129144161,0.06624331600225977,0.2461611801381823,-0.5365115565809986,-0.24221132899251827,-1.2956536049018468,0.7372535957044981,3.3503698232892996,1.40700578874686,0.21089999179645574,1.7601302536193415,-0.471302155269236,-0.6707700428550947,0.4006592727447067,-1.3232487120310719,0.5648593382990243,-0.471302155269236,0.19313737866175912,-0.10391188008073553,1.6420560339548476,-0.3237756446783554,3.6994359897329634,0.0846519922036011,-1.673164747906431,-1.0316061132826644,0.7979678150313219,-0.7167208001281143,0.010434058495094673,0.6599073521556105,-1.0063130127151403,0.5487721681964972,-0.30320435577832683,-0.20213507046424417,0.04773817048517167,-0.16251400074754818,0.19313737866175912,-0.1822683354853108,0.13930990831158938,-0.40730404219216754,-0.1822683354853108,-0.9315555215226238,-0.10391188008073553,0.17528547971368946,0.15734332005004562,-0.4285051553274654,0.9018467708360485,3.7489696574923244,0.029135457235295485,-0.8343882553406996,2.6118073444066714,2.5364613381868493
| 3,447
|
Optic disc pallor
| 13
| 49
| 2.319644
| 0.02036
|
O75306,Q9H3H5,Q9H6K4,Q96L58,Q86Y39,O43676,Q9H061,P03886,Q96CU9,Q10713,O60313,Q9Y6M9,Q9NPL8
|
Drugs and Diseases
|
Human Phenotype Ontology
|
msigdb_hp
|
382,224,67,390,71,8,13,146,180,344,365,86,193
|
2182,588,3320,2185,1462,8,840,365,1327,382,706,2971,2117,1604,437,824,568,146,1162,2546,1719,3336,2249,3345,3214,749,2134,344,652,1239,71,1111,1307,1053,2159,2267,180,390,2875,2268,13,1456,224,67,193,3039,1658,2180,86
|
-0.3237756446783554,0.5968202922124238,-1.241143026979425,-0.3237756446783554,-0.04627372815783212,3.873674680039861,0.3156532797160656,1.059363369451296,0.010434058495094673,1.0028619724328278,0.4341047300866308,-0.7632999174742385,-0.30320435577832683,-0.10391188008073553,0.8871862971088242,0.3328168814905901,0.6285012150671874,2.1257159606954366,0.10296527861463395,-0.49290160023430213,-0.14287070187912912,-1.2956536049018468,-0.3444696497798871,-1.3232487120310719,-1.0316061132826644,0.4006592727447067,-0.30320435577832683,1.1287949380852866,0.5163809909451085,0.06624331600225977,2.7312521573765434,0.13930990831158938,0.029135457235295485,0.17528547971368946,-0.30320435577832683,-0.3444696497798871,1.9195087103543416,0.9886001370636728,-0.6707700428550947,-0.3444696497798871,3.7489696574923244,-0.027269365976897105,1.6897278697989968,2.7583110565843194,1.8292524636194953,-0.8105262504581725,-0.10391188008073553,-0.30320435577832683,2.5364613381868493
| 3,447
|
acyltransferase
| 11
| 19
| 2.312265
| 0.020763
|
Q8NCC3,P35610,Q8NF37,P23786,Q99943,Q9HCL2,Q86UL3,P49354,P14324,P50416,O15228
|
Functions
|
Panther Protein class
|
panther_protein_class
|
289,321,264,395,473,506,471,342,402,316,567
|
567,402,395,2633,321,1978,342,644,316,847,1678,471,289,264,1179,473,1359,506,799
|
0.6285012150671874,0.9599094643624182,0.9742827906130651,-0.5365115565809986,1.1969478078787075,-0.24221132899251827,1.1287949380852866,0.5163809909451085,1.2238621747785425,0.3156532797160656,-0.12333709979746053,0.8279499860422683,1.3296137106483024,1.445109921894803,0.10296527861463395,0.8279499860422683,0.010434058495094673,0.75252729309868,0.3668988157742944
| 3,447
|
Cellular ion homeostasis
| 29
| 88
| 2.309515
| 0.020915
|
P0CG08,Q9Y6M7,P09601,P16615,O75880,Q9Y487,P51572,P20020,P12277,Q9UM00,O95202,Q9NVV0,Q93050,Q96A33,Q8NEW0,P05023,O76024,Q8N511,P51790,P55011,P50897,P98194,O43819,Q92544,Q9HD20,P23634,Q8WWC4,O75503,Q7L0J3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
514,530,11,136,520,149,404,403,538,285,169,563,175,178,55,309,189,63,448,449,77,215,340,223,102,483,363,492,123
|
2066,726,666,340,2581,1258,763,492,520,3149,189,169,2626,2391,309,1969,1970,1163,3428,1715,2541,1226,11,514,1971,538,1227,2845,136,2368,3021,2075,403,2393,483,949,747,3313,1517,2705,2130,2198,77,1168,404,448,1677,828,449,1076,1824,2370,215,1779,2457,2334,2142,1832,592,3236,558,2340,123,2608,63,966,1492,55,363,223,175,178,1213,2468,2109,1540,994,102,563,1763,1253,1032,285,1768,149,2180,3273,530
|
-0.28275422227728697,0.4174209793635682,0.4836959753352828,1.1287949380852866,-0.5146374427323911,0.04773817048517167,0.3838188193188344,0.7828838337881776,0.7065124420438686,-0.9562907027938861,1.840651870597142,1.9858304188448097,-0.5365115565809986,-0.4285051553274654,1.237246593120908,-0.24221132899251827,-0.24221132899251827,0.10296527861463395,-2.333607799065281,-0.14287070187912912,-0.49290160023430213,0.06624331600225977,3.804859663855004,0.7219155083838219,-0.24221132899251827,0.6755089741541659,0.06624331600225977,-0.6707700428550947,2.1572887559147627,-0.40730404219216754,-0.8105262504581725,-0.28275422227728697,0.9599094643624182,-0.4285051553274654,0.7979678150313219,0.2285742779294462,0.4006592727447067,-1.214219613160026,-0.06538144972417397,-0.5806822940457038,-0.30320435577832683,-0.3237756446783554,2.685738533107751,0.10296527861463395,0.9599094643624182,0.8576880629169049,-0.12333709979746053,0.3328168814905901,0.8576880629169049,0.15734332005004562,-0.1822683354853108,-0.40730404219216754,1.7133407362411066,-0.16251400074754818,-0.44983727276622243,-0.3862322082359554,-0.30320435577832683,-0.1822683354853108,0.5968202922124238,-1.0570912841778808,0.6442383099094389,-0.3862322082359554,2.2607083952402736,-0.5146374427323911,2.776248153122407,0.2285742779294462,-0.04627372815783212,2.8559762796306747,1.0733544735925842,1.6897278697989968,1.9417437419205628,1.9306423672509032,0.0846519922036011,-0.44983727276622243,-0.28275422227728697,-0.06538144972417397,0.21089999179645574,2.42065765575822,0.6442383099094389,-0.14287070187912912,0.06624331600225977,0.19313737866175912,1.3555894999858193,-0.14287070187912912,2.0938827725307765,-0.30320435577832683,-1.1086506296557357,0.7065124420438686
| 3,447
|
Purine nucleotide transmembrane transporter activity
| 7
| 9
| 2.306869
| 0.021062
|
Q8TB61,P05141,Q86VD7,P12235,Q6KCM7,P12236,O43808
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
64,258,332,208,306,183,347
|
347,258,208,183,661,306,425,332,64
|
1.115012567814737,1.4702992943855286,1.7717381563510717,1.8859120022561358,0.500075572431892,1.2505830026120932,0.9164488273167519,1.1698368489882653,2.776248153122407
| 3,447
|
Protein serine kinase activity
| 33
| 86
| 4.864203
| 0.000001
|
Q9BUB5,Q16539,Q8IW41,Q9H4A3,Q13546,P51812,P49761,Q14012,P11802,Q8TD19,Q9BVS4,Q96GX5,Q96SB4,Q8WZ42,Q9BRS2,O14976,P51617,Q00535,Q9Y3S1,Q15418,O14757,O14733,O43683,Q86UE8,Q86Y07,P33981,O14920,O14965,P49841,P54646,O60566,Q96KB5,Q00534
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
403,394,10,11,257,13,506,510,142,552,278,23,555,427,430,408,290,176,196,61,65,183,67,317,487,208,221,468,475,477,356,520,242
|
183,65,221,1388,468,408,686,67,356,1536,3505,687,2091,2289,1120,1317,142,3542,2606,1248,1249,1812,1057,1121,1815,208,1476,1969,538,1259,1002,506,1005,475,1336,290,13,1684,477,1742,1627,242,176,1012,1423,1560,2183,1632,2688,779,257,878,2425,510,833,61,1634,1279,394,1020,2122,2367,1141,2498,317,487,10,552,427,2754,23,520,2376,1924,555,1772,1578,430,403,278,1710,11,1718,1784,196,716
|
1.4582167193470499,2.184093386153049,1.3430177439240172,0.22000783347747066,0.9191355351926671,0.9963842539114091,0.6868888119615674,2.146041665971875,1.073551824278558,0.14186560484493307,-1.5222926203028688,0.6868888119615674,-0.17171116116859408,-0.2897362923580755,0.3760035130473384,0.25904250556837555,1.611557358304762,-1.7230890308303868,-0.48697317960573294,0.2980531923406561,0.2980531923406561,-0.014717140094497816,0.4149435883630969,0.3760035130473384,-0.014717140094497816,1.3814361078072093,0.18094894503092676,-0.09316168383661999,0.8418043225749562,0.2980531923406561,0.4538605613386647,0.8804803264068664,0.4538605613386647,0.9191355351926671,0.25904250556837555,1.1891538675508655,3.618950764638868,0.06362460524619651,0.9191355351926671,0.024466452206715977,0.10275757306645614,1.3045804843879147,1.496579247199708,0.4538605613386647,0.22000783347747066,0.14186560484493307,-0.21102594097074423,0.10275757306645614,-0.5264977250215082,0.6093015947704223,1.266124183862369,0.5316260405382865,-0.36855296551083955,0.8804803264068664,0.5704749577465287,2.222128940045359,0.10275757306645614,0.2980531923406561,1.034978100199594,0.4538605613386647,-0.17171116116859408,-0.3291314594756453,0.3760035130473384,-0.4080005745537821,1.1506395499979194,0.9191355351926671,4.105329277835919,0.8418043225749562,0.9963842539114091,-0.566047472031465,3.0927128631856373,0.8804803264068664,-0.3291314594756453,-0.05392643070728478,0.8418043225749562,0.024466452206715977,0.14186560484493307,0.9963842539114091,1.034978100199594,1.2276486948314262,0.06362460524619651,3.955897930278428,0.06362460524619651,0.024466452206715977,1.4582167193470499,0.6868888119615674
| 3,643
|
Serine/threonine-protein kinase, active site [IPR008271]
| 29
| 72
| 4.722491
| 0.000002
|
Q9BUB5,Q8IW41,Q9H4A3,Q13546,P49761,P51812,Q14012,P11802,Q8TD19,Q96GX5,Q96SB4,O14976,P51617,Q00535,Q9Y3S1,Q15418,O14757,O15111,O14733,O43683,Q86UE8,Q86Y07,P33981,O14965,O14920,P49841,P54646,Q96KB5,Q00534
|
Sequence
|
InterPro Active site
|
interpro_active_site
|
403,10,11,257,506,13,510,142,552,23,555,408,290,176,196,61,65,66,183,67,317,487,208,468,221,475,477,520,242
|
183,65,221,468,408,66,686,67,1536,3505,2091,2289,1120,1317,142,3542,2606,1248,1249,1812,3605,1057,1121,1815,208,1476,538,1259,1002,506,1005,475,1336,290,13,1684,477,1742,242,176,1012,1560,1632,2688,257,878,2425,510,833,61,1634,1279,1020,2122,2367,1141,317,487,10,552,2754,23,520,2376,555,1772,1578,403,1710,11,1718,196
|
1.4582167193470499,2.184093386153049,1.3430177439240172,0.9191355351926671,0.9963842539114091,2.146041665971875,0.6868888119615674,2.146041665971875,0.14186560484493307,-1.5222926203028688,-0.17171116116859408,-0.2897362923580755,0.3760035130473384,0.25904250556837555,1.611557358304762,-1.7230890308303868,-0.48697317960573294,0.2980531923406561,0.2980531923406561,-0.014717140094497816,-2.4905544051565287,0.4149435883630969,0.3760035130473384,-0.014717140094497816,1.3814361078072093,0.18094894503092676,0.8418043225749562,0.2980531923406561,0.4538605613386647,0.8804803264068664,0.4538605613386647,0.9191355351926671,0.25904250556837555,1.1891538675508655,3.618950764638868,0.06362460524619651,0.9191355351926671,0.024466452206715977,1.3045804843879147,1.496579247199708,0.4538605613386647,0.14186560484493307,0.10275757306645614,-0.5264977250215082,1.266124183862369,0.5316260405382865,-0.36855296551083955,0.8804803264068664,0.5704749577465287,2.222128940045359,0.10275757306645614,0.2980531923406561,0.4538605613386647,-0.17171116116859408,-0.3291314594756453,0.3760035130473384,1.1506395499979194,0.9191355351926671,4.105329277835919,0.8418043225749562,-0.566047472031465,3.0927128631856373,0.8804803264068664,-0.3291314594756453,0.8418043225749562,0.024466452206715977,0.14186560484493307,1.034978100199594,0.06362460524619651,3.955897930278428,0.06362460524619651,1.4582167193470499
| 3,643
|
Serine/threonine-protein kinase
| 34
| 87
| 4.699505
| 0.000003
|
Q9BUB5,Q16539,Q8IW41,Q9H4A3,Q13546,P51812,P49761,Q14012,P11802,Q8TD19,Q9BVS4,Q96GX5,Q96SB4,Q8WZ42,Q9BRS2,O14976,P51617,Q00535,Q9Y3S1,Q15418,O14757,O15111,O14733,O43683,Q86UE8,Q86Y07,P33981,O14920,O14965,P49841,P54646,O60566,Q96KB5,Q00534
|
Functions
|
Protein Atlas Molecular function
|
protein_atlas_molecular_function
|
403,394,10,11,257,13,506,510,142,552,278,23,555,427,430,408,290,176,196,61,65,66,183,67,317,487,208,221,468,475,477,356,520,242
|
183,65,221,1388,468,408,66,686,67,356,1536,3505,687,2091,2289,1120,1317,142,3542,2606,1248,1249,1812,3605,1057,1121,1815,208,1476,1969,538,1259,1002,506,1005,475,1336,290,13,1684,477,1742,1627,242,176,1012,1423,1560,2183,1632,2688,779,257,878,2425,510,833,61,1634,1279,394,1020,2122,2367,1141,317,487,10,552,427,2754,23,520,2376,1924,555,1772,1578,430,403,278,1710,11,1718,1784,196,716
|
1.4582167193470499,2.184093386153049,1.3430177439240172,0.22000783347747066,0.9191355351926671,0.9963842539114091,2.146041665971875,0.6868888119615674,2.146041665971875,1.073551824278558,0.14186560484493307,-1.5222926203028688,0.6868888119615674,-0.17171116116859408,-0.2897362923580755,0.3760035130473384,0.25904250556837555,1.611557358304762,-1.7230890308303868,-0.48697317960573294,0.2980531923406561,0.2980531923406561,-0.014717140094497816,-2.4905544051565287,0.4149435883630969,0.3760035130473384,-0.014717140094497816,1.3814361078072093,0.18094894503092676,-0.09316168383661999,0.8418043225749562,0.2980531923406561,0.4538605613386647,0.8804803264068664,0.4538605613386647,0.9191355351926671,0.25904250556837555,1.1891538675508655,3.618950764638868,0.06362460524619651,0.9191355351926671,0.024466452206715977,0.10275757306645614,1.3045804843879147,1.496579247199708,0.4538605613386647,0.22000783347747066,0.14186560484493307,-0.21102594097074423,0.10275757306645614,-0.5264977250215082,0.6093015947704223,1.266124183862369,0.5316260405382865,-0.36855296551083955,0.8804803264068664,0.5704749577465287,2.222128940045359,0.10275757306645614,0.2980531923406561,1.034978100199594,0.4538605613386647,-0.17171116116859408,-0.3291314594756453,0.3760035130473384,1.1506395499979194,0.9191355351926671,4.105329277835919,0.8418043225749562,0.9963842539114091,-0.566047472031465,3.0927128631856373,0.8804803264068664,-0.3291314594756453,-0.05392643070728478,0.8418043225749562,0.024466452206715977,0.14186560484493307,0.9963842539114091,1.034978100199594,1.2276486948314262,0.06362460524619651,3.955897930278428,0.06362460524619651,0.024466452206715977,1.4582167193470499,0.6868888119615674
| 3,643
|
non-receptor serine/threonine protein kinase
| 28
| 79
| 4.384552
| 0.000012
|
Q9BUB5,Q16539,Q8IW41,Q9H4A3,Q13546,P49761,Q14012,P11802,Q9BVS4,Q96GX5,Q96SB4,Q9BRS2,Q00535,Q9Y3S1,O14757,O15111,O14733,O43683,Q86UE8,Q86Y07,P33981,O14920,O14965,P49841,P54646,O60566,Q96KB5,Q00534
|
Functions
|
Panther Protein class
|
panther_protein_class
|
403,394,10,11,257,506,510,142,278,23,555,430,176,196,65,66,183,67,317,487,208,221,468,475,477,356,520,242
|
183,65,3174,221,468,66,686,67,356,1536,2091,2289,1120,1317,142,3542,2606,1248,1812,3605,1057,1121,1815,208,1476,1969,538,1259,1002,506,1005,475,1336,1684,477,1742,1627,242,176,1012,1423,1560,2183,1632,2688,779,257,878,2425,510,2430,3035,833,1634,1279,394,1020,2122,2367,1141,317,487,741,10,2754,23,520,1924,555,1578,430,403,278,11,1718,1784,809,196,2083
|
1.4582167193470499,2.184093386153049,-0.9628854457235239,1.3430177439240172,0.9191355351926671,2.146041665971875,0.6868888119615674,2.146041665971875,1.073551824278558,0.14186560484493307,-0.17171116116859408,-0.2897362923580755,0.3760035130473384,0.25904250556837555,1.611557358304762,-1.7230890308303868,-0.48697317960573294,0.2980531923406561,-0.014717140094497816,-2.4905544051565287,0.4149435883630969,0.3760035130473384,-0.014717140094497816,1.3814361078072093,0.18094894503092676,-0.09316168383661999,0.8418043225749562,0.2980531923406561,0.4538605613386647,0.8804803264068664,0.4538605613386647,0.9191355351926671,0.25904250556837555,0.06362460524619651,0.9191355351926671,0.024466452206715977,0.10275757306645614,1.3045804843879147,1.496579247199708,0.4538605613386647,0.22000783347747066,0.14186560484493307,-0.21102594097074423,0.10275757306645614,-0.5264977250215082,0.6093015947704223,1.266124183862369,0.5316260405382865,-0.36855296551083955,0.8804803264068664,-0.36855296551083955,-0.8038633863877657,0.5704749577465287,0.10275757306645614,0.2980531923406561,1.034978100199594,0.4538605613386647,-0.17171116116859408,-0.3291314594756453,0.3760035130473384,1.1506395499979194,0.9191355351926671,0.6481061483680024,4.105329277835919,-0.566047472031465,3.0927128631856373,0.8804803264068664,-0.05392643070728478,0.8418043225749562,0.14186560484493307,0.9963842539114091,1.034978100199594,1.2276486948314262,3.955897930278428,0.06362460524619651,0.024466452206715977,0.6093015947704223,1.4582167193470499,-0.132423168996273
| 3,643
|
Protein kinase domain [IPR000719]
| 31
| 88
| 4.056624
| 0.00005
|
Q9BUB5,Q16539,Q8IW41,Q9H4A3,Q13546,P51812,P49761,Q14012,P11802,Q8TD19,Q96GX5,Q96SB4,Q8WZ42,O14976,P51617,Q00535,Q9Y3S1,Q15418,O14757,O15111,O14733,O43683,Q86UE8,Q86Y07,P33981,O14920,O14965,P49841,P54646,Q96KB5,Q00534
|
Sequence
|
InterPro Domain
|
interpro_domain
|
403,394,10,11,257,13,506,510,142,552,23,555,427,408,290,176,196,61,65,66,183,67,317,487,208,221,468,475,477,520,242
|
183,65,221,1388,468,408,66,686,67,1536,3505,687,2091,2289,1120,2411,3060,1317,142,3367,3542,2606,1248,1249,1812,3605,1057,1121,3183,1815,208,1126,1476,538,1259,1002,506,1005,475,1336,290,13,1684,477,1742,242,176,1012,1423,1560,2117,2183,1632,2688,257,878,2425,510,833,2801,61,1634,1279,394,1020,2122,2367,1141,317,487,741,10,552,427,2754,23,520,2376,555,1772,1578,403,1710,11,1718,1784,809,196
|
1.4582167193470499,2.184093386153049,1.3430177439240172,0.22000783347747066,0.9191355351926671,0.9963842539114091,2.146041665971875,0.6868888119615674,2.146041665971875,0.14186560484493307,-1.5222926203028688,0.6868888119615674,-0.17171116116859408,-0.2897362923580755,0.3760035130473384,-0.36855296551083955,-0.8435837193418066,0.25904250556837555,1.611557358304762,-1.2021058814321368,-1.7230890308303868,-0.48697317960573294,0.2980531923406561,0.2980531923406561,-0.014717140094497816,-2.4905544051565287,0.4149435883630969,0.3760035130473384,-0.9628854457235239,-0.014717140094497816,1.3814361078072093,0.3760035130473384,0.18094894503092676,0.8418043225749562,0.2980531923406561,0.4538605613386647,0.8804803264068664,0.4538605613386647,0.9191355351926671,0.25904250556837555,1.1891538675508655,3.618950764638868,0.06362460524619651,0.9191355351926671,0.024466452206715977,1.3045804843879147,1.496579247199708,0.4538605613386647,0.22000783347747066,0.14186560484493307,-0.17171116116859408,-0.21102594097074423,0.10275757306645614,-0.5264977250215082,1.266124183862369,0.5316260405382865,-0.36855296551083955,0.8804803264068664,0.5704749577465287,-0.605622205270541,2.222128940045359,0.10275757306645614,0.2980531923406561,1.034978100199594,0.4538605613386647,-0.17171116116859408,-0.3291314594756453,0.3760035130473384,1.1506395499979194,0.9191355351926671,0.6481061483680024,4.105329277835919,0.8418043225749562,0.9963842539114091,-0.566047472031465,3.0927128631856373,0.8804803264068664,-0.3291314594756453,0.8418043225749562,0.024466452206715977,0.14186560484493307,1.034978100199594,0.06362460524619651,3.955897930278428,0.06362460524619651,0.024466452206715977,0.6093015947704223,1.4582167193470499
| 3,643
|
Protein serine threonine tyrosine kinase activity
| 33
| 94
| 4.03069
| 0.000056
|
Q9BUB5,Q16539,Q8IW41,Q9H4A3,Q13546,P51812,P49761,Q14012,P11802,Q8TD19,Q9BVS4,Q96GX5,Q96SB4,Q8WZ42,Q9BRS2,O14976,P51617,Q00535,Q9Y3S1,Q15418,O14757,O14733,O43683,Q86UE8,Q86Y07,P33981,O14920,O14965,P49841,P54646,O60566,Q96KB5,Q00534
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
403,394,10,11,257,13,506,510,142,552,278,23,555,427,430,408,290,176,196,61,65,183,67,317,487,208,221,468,475,477,356,520,242
|
183,65,221,1388,468,408,686,67,356,1536,3505,687,2091,2289,1120,2411,3060,1317,142,3367,3542,2606,1248,1249,1812,1057,1121,3183,1815,208,1126,1476,1969,538,1259,1002,506,1005,475,1336,290,13,1684,477,1742,1627,242,176,1012,1423,1560,2183,1632,2688,779,257,878,2425,510,833,2801,61,1634,1279,394,1020,2122,2367,1141,2498,317,487,10,552,427,2754,23,520,2376,1924,555,1772,1578,430,403,278,1710,11,3521,1718,1784,2273,196,716
|
1.4582167193470499,2.184093386153049,1.3430177439240172,0.22000783347747066,0.9191355351926671,0.9963842539114091,0.6868888119615674,2.146041665971875,1.073551824278558,0.14186560484493307,-1.5222926203028688,0.6868888119615674,-0.17171116116859408,-0.2897362923580755,0.3760035130473384,-0.36855296551083955,-0.8435837193418066,0.25904250556837555,1.611557358304762,-1.2021058814321368,-1.7230890308303868,-0.48697317960573294,0.2980531923406561,0.2980531923406561,-0.014717140094497816,0.4149435883630969,0.3760035130473384,-0.9628854457235239,-0.014717140094497816,1.3814361078072093,0.3760035130473384,0.18094894503092676,-0.09316168383661999,0.8418043225749562,0.2980531923406561,0.4538605613386647,0.8804803264068664,0.4538605613386647,0.9191355351926671,0.25904250556837555,1.1891538675508655,3.618950764638868,0.06362460524619651,0.9191355351926671,0.024466452206715977,0.10275757306645614,1.3045804843879147,1.496579247199708,0.4538605613386647,0.22000783347747066,0.14186560484493307,-0.21102594097074423,0.10275757306645614,-0.5264977250215082,0.6093015947704223,1.266124183862369,0.5316260405382865,-0.36855296551083955,0.8804803264068664,0.5704749577465287,-0.605622205270541,2.222128940045359,0.10275757306645614,0.2980531923406561,1.034978100199594,0.4538605613386647,-0.17171116116859408,-0.3291314594756453,0.3760035130473384,-0.4080005745537821,1.1506395499979194,0.9191355351926671,4.105329277835919,0.8418043225749562,0.9963842539114091,-0.566047472031465,3.0927128631856373,0.8804803264068664,-0.3291314594756453,-0.05392643070728478,0.8418043225749562,0.024466452206715977,0.14186560484493307,0.9963842539114091,1.034978100199594,1.2276486948314262,0.06362460524619651,3.955897930278428,-1.5624109538513453,0.06362460524619651,0.024466452206715977,-0.2503677045331832,1.4582167193470499,0.6868888119615674
| 3,643
|
Protein polyubiquitination
| 31
| 63
| 4.000804
| 0.000063
|
Q7Z7E8,Q9H000,P22681,O75150,Q99728,P98170,Q96J02,P52888,P49427,Q96PU5,Q12933,Q9C0C9,Q16763,Q9NZJ0,Q9UJX3,Q8TDB6,P55786,Q149N8,Q63HN8,Q13867,P19474,Q13618,Q14139,Q9ULT8,P38398,Q7Z6Z7,Q15386,Q66K64,Q8NEZ5,Q96FW1,Q9UBS8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
138,676,143,22,556,664,305,540,418,323,455,326,58,60,64,203,311,584,315,698,574,582,211,756,339,630,369,246,111,402,529
|
2156,22,1397,864,1666,1321,574,143,1678,2032,3140,339,418,540,311,1413,1623,827,1826,938,664,1269,455,1487,733,1072,582,698,2309,211,2429,584,369,58,2995,315,246,2746,630,138,2059,111,203,402,305,323,556,326,676,1934,2271,60,529,3527,2390,64,1786,2655,756,2967,1305,976,911
|
-0.21102594097074423,3.0927128631856373,0.22000783347747066,0.5316260405382865,0.06362460524619651,0.25904250556837555,0.8031073486334814,1.611557358304762,0.06362460524619651,-0.132423168996273,-0.9230949351912728,1.1121055878194461,0.9963842539114091,0.8418043225749562,1.1506395499979194,0.22000783347747066,0.10275757306645614,0.5704749577465287,-0.014717140094497816,0.49275464296587623,0.7256497757208881,0.2980531923406561,0.9577701211888938,0.18094894503092676,0.6481061483680024,0.4149435883630969,0.8031073486334814,0.6868888119615674,-0.2897362923580755,1.3814361078072093,-0.36855296551083955,0.8031073486334814,1.073551824278558,2.2981519715712917,-0.7641668235232126,1.1506395499979194,1.3045804843879147,-0.566047472031465,0.7643892266436848,1.6498473485953888,-0.132423168996273,1.764610992500279,1.4198357192420223,1.034978100199594,1.1891538675508655,1.1506395499979194,0.8418043225749562,1.1506395499979194,0.7256497757208881,-0.05392643070728478,-0.2503677045331832,2.2601484336349698,0.8804803264068664,-1.6025499029064922,-0.3291314594756453,2.222128940045359,0.024466452206715977,-0.48697317960573294,0.6481061483680024,-0.724494224850264,0.2980531923406561,0.49275464296587623,0.5316260405382865
| 3,643
|
Ubiquitin like protein transferase activity
| 49
| 89
| 3.95975
| 0.000075
|
Q8N806,Q9UBS8,Q7Z7E8,Q9H000,Q14527,P22681,O75150,Q9Y314,Q8TBC4,Q99728,Q86UK7,P98170,Q9UDY8,O43164,Q96J02,Q9H270,Q93034,P49427,Q96PU5,Q9Y3I1,Q9C0C9,Q12933,Q16763,Q9NZJ0,Q8N2W9,Q8TDB6,P68036,Q149N8,Q63HN8,Q5W0B1,P61081,Q9NT62,P19474,P61088,Q13618,Q14139,Q9ULT8,P38398,Q9UII4,Q8NCN4,Q7Z6Z7,Q8IVV7,Q15386,Q9UPN9,Q9Y4X5,Q8NEZ5,Q7Z569,Q9NR09,O95155
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
789,529,138,676,258,143,22,684,956,556,274,664,563,650,305,965,845,418,323,860,326,455,58,60,191,203,938,584,315,199,935,218,574,827,582,211,756,339,496,227,630,372,369,644,911,111,123,528,864
|
1662,650,22,987,1396,3588,2021,2471,2771,1397,864,1666,2409,1321,574,143,339,418,2103,1413,2681,935,1623,827,938,664,1269,1749,455,1561,582,211,1016,258,2429,584,369,58,1495,1350,2436,2995,199,315,1756,2746,1758,2194,123,3267,630,138,274,2059,372,191,789,227,111,956,203,845,1087,305,323,1848,2327,556,326,676,2002,965,528,218,2271,60,3357,529,563,496,2390,2655,756,2967,1305,644,684,860,911
|
0.06362460524619651,0.7256497757208881,3.0927128631856373,0.4538605613386647,0.22000783347747066,-2.1261701689752903,-0.132423168996273,-0.4080005745537821,-0.605622205270541,0.22000783347747066,0.5316260405382865,0.06362460524619651,-0.36855296551083955,0.25904250556837555,0.8031073486334814,1.611557358304762,1.1121055878194461,0.9963842539114091,-0.17171116116859408,0.22000783347747066,-0.5264977250215082,0.49275464296587623,0.10275757306645614,0.5704749577465287,0.49275464296587623,0.7256497757208881,0.2980531923406561,0.024466452206715977,0.9577701211888938,0.14186560484493307,0.8031073486334814,1.3814361078072093,0.4538605613386647,1.266124183862369,-0.36855296551083955,0.8031073486334814,1.073551824278558,2.2981519715712917,0.18094894503092676,0.25904250556837555,-0.36855296551083955,-0.7641668235232126,1.4198357192420223,1.1506395499979194,0.024466452206715977,-0.566047472031465,0.024466452206715977,-0.21102594097074423,1.7263740388712179,-1.0425353636919736,0.7643892266436848,1.6498473485953888,1.2276486948314262,-0.132423168996273,1.073551824278558,1.4582167193470499,0.6093015947704223,1.3430177439240172,1.764610992500279,0.49275464296587623,1.4198357192420223,0.5704749577465287,0.4149435883630969,1.1891538675508655,1.1506395499979194,-0.014717140094497816,-0.2897362923580755,0.8418043225749562,1.1506395499979194,0.7256497757208881,-0.09316168383661999,0.49275464296587623,0.8804803264068664,1.3814361078072093,-0.2503677045331832,2.2601484336349698,-1.1621798444446965,0.8804803264068664,0.8418043225749562,0.9191355351926671,-0.3291314594756453,-0.48697317960573294,0.6481061483680024,-0.724494224850264,0.2980531923406561,0.7643892266436848,0.7256497757208881,0.5704749577465287,0.5316260405382865
| 3,643
|
Zinc finger, RING-type [IPR001841]
| 21
| 40
| 3.914788
| 0.00009
|
Q96T51,O15344,Q9H000,Q14527,P22681,O75150,Q86UK7,Q99728,P98170,Q12933,Q8TDB6,Q149N8,Q63HN8,Q99590,Q5W0B1,P19474,P38398,Q8NCN4,Q9UPN9,Q7Z569,Q9UBS8
|
Sequence
|
InterPro Domain
|
interpro_domain
|
265,498,676,258,143,22,274,556,664,455,203,584,315,76,199,574,339,227,644,123,529
|
1662,498,650,22,1396,2471,1666,1538,1321,574,143,339,1197,664,1749,455,1561,1016,258,584,2995,199,315,2746,123,3267,274,227,203,265,1848,2327,76,556,676,965,529,2273,644,911
|
0.06362460524619651,0.8804803264068664,0.7256497757208881,3.0927128631856373,0.22000783347747066,-0.4080005745537821,0.06362460524619651,0.14186560484493307,0.25904250556837555,0.8031073486334814,1.611557358304762,1.1121055878194461,0.3370401206025548,0.7256497757208881,0.024466452206715977,0.9577701211888938,0.14186560484493307,0.4538605613386647,1.266124183862369,0.8031073486334814,-0.7641668235232126,1.4198357192420223,1.1506395499979194,-0.566047472031465,1.7263740388712179,-1.0425353636919736,1.2276486948314262,1.3430177439240172,1.4198357192420223,1.266124183862369,-0.014717140094497816,-0.2897362923580755,2.0698892959609982,0.8418043225749562,0.7256497757208881,0.49275464296587623,0.8804803264068664,-0.2503677045331832,0.7643892266436848,0.5316260405382865
| 3,643
|
Microtubule associated complex
| 27
| 59
| 3.757472
| 0.000172
|
Q9BW19,O15344,A0MZ66,Q8NCM8,Q99661,Q9UJW0,P29372,Q66K74,P49023,Q07866,Q86Y91,Q13561,Q9Y496,Q9H6D7,Q96EX3,Q14807,P27816,Q9H0B6,Q7Z4H7,Q96S59,Q15058,O14965,O43237,O60333,Q9Y6G9,P63167,O95793
|
Localization
|
GO Cellular component
|
msigdb_gocc
|
800,498,497,14,675,31,414,421,289,454,190,456,332,463,322,583,444,749,79,215,481,468,719,720,647,363,611
|
497,2278,468,498,719,720,2921,1537,2408,611,2092,444,414,1816,1885,1820,289,2540,2614,870,2042,363,1202,1688,454,941,2118,456,945,1833,583,481,1490,421,786,79,190,1915,14,1769,3047,322,1574,2754,2133,3122,215,675,2204,800,749,463,1032,1299,1658,31,1169,332,647
|
0.8804803264068664,-0.2897362923580755,0.9191355351926671,0.8804803264068664,0.6481061483680024,0.6481061483680024,-0.724494224850264,0.14186560484493307,-0.36855296551083955,0.7643892266436848,-0.17171116116859408,0.9577701211888938,0.9963842539114091,-0.014717140094497816,-0.05392643070728478,-0.014717140094497816,1.1891538675508655,-0.44747405503507703,-0.48697317960573294,0.5316260405382865,-0.132423168996273,1.073551824278558,0.3370401206025548,0.06362460524619651,0.9577701211888938,0.49275464296587623,-0.17171116116859408,0.9577701211888938,0.49275464296587623,-0.014717140094497816,0.8031073486334814,0.9191355351926671,0.18094894503092676,0.9963842539114091,0.6093015947704223,2.031788427242603,1.4582167193470499,-0.05392643070728478,3.581448559077415,0.024466452206715977,-0.8038633863877657,1.1506395499979194,0.14186560484493307,-0.566047472031465,-0.17171116116859408,-0.8833276315156983,1.3814361078072093,0.7256497757208881,-0.21102594097074423,0.6093015947704223,0.6481061483680024,0.9577701211888938,0.4538605613386647,0.2980531923406561,0.10275757306645614,2.752986257481613,0.3760035130473384,1.1506395499979194,0.7643892266436848
| 3,643
|
Protein serine threonine kinase activity
| 36
| 103
| 3.748105
| 0.000178
|
Q9BUB5,Q16539,Q8IW41,Q9H4A3,Q13546,P51812,P49761,Q14012,P11802,Q8TD19,Q9BVS4,Q96GX5,Q96SB4,Q8WZ42,Q9BRS2,O14976,P51617,Q00535,Q9Y3S1,Q15418,O14757,O15111,O14733,O43683,P46020,Q13501,Q86UE8,Q86Y07,P33981,O14920,O14965,P49841,P54646,O60566,Q96KB5,Q00534
|
Functions
|
GO Molecular function
|
msigdb_gomf
|
403,394,10,11,257,13,506,510,142,552,278,23,555,427,430,408,290,176,196,61,65,66,183,67,310,70,317,487,208,221,468,475,477,356,520,242
|
183,65,3174,221,1388,468,408,66,686,67,356,2345,1536,1395,2286,3505,687,2091,2289,1120,1317,3137,142,3542,2606,1248,1249,1812,3605,3098,1057,1121,1815,208,1476,1969,310,538,1259,1002,506,1005,475,1336,290,13,1684,2842,477,1899,1742,1627,242,176,1012,777,1423,1560,2183,1632,70,2688,779,257,878,2425,510,3035,833,61,1634,1279,394,1020,2122,2367,1141,2498,317,487,741,10,552,427,2754,23,520,2376,1924,555,1772,1578,430,403,2866,278,1710,11,1718,1784,809,196,716
|
1.4582167193470499,2.184093386153049,-0.9628854457235239,1.3430177439240172,0.22000783347747066,0.9191355351926671,0.9963842539114091,2.146041665971875,0.6868888119615674,2.146041665971875,1.073551824278558,-0.3291314594756453,0.14186560484493307,0.22000783347747066,-0.2897362923580755,-1.5222926203028688,0.6868888119615674,-0.17171116116859408,-0.2897362923580755,0.3760035130473384,0.25904250556837555,-0.9230949351912728,1.611557358304762,-1.7230890308303868,-0.48697317960573294,0.2980531923406561,0.2980531923406561,-0.014717140094497816,-2.4905544051565287,-0.8833276315156983,0.4149435883630969,0.3760035130473384,-0.014717140094497816,1.3814361078072093,0.18094894503092676,-0.09316168383661999,1.1506395499979194,0.8418043225749562,0.2980531923406561,0.4538605613386647,0.8804803264068664,0.4538605613386647,0.9191355351926671,0.25904250556837555,1.1891538675508655,3.618950764638868,0.06362460524619651,-0.6452217131559657,0.9191355351926671,-0.05392643070728478,0.024466452206715977,0.10275757306645614,1.3045804843879147,1.496579247199708,0.4538605613386647,0.6093015947704223,0.22000783347747066,0.14186560484493307,-0.21102594097074423,0.10275757306645614,2.107973672153446,-0.5264977250215082,0.6093015947704223,1.266124183862369,0.5316260405382865,-0.36855296551083955,0.8804803264068664,-0.8038633863877657,0.5704749577465287,2.222128940045359,0.10275757306645614,0.2980531923406561,1.034978100199594,0.4538605613386647,-0.17171116116859408,-0.3291314594756453,0.3760035130473384,-0.4080005745537821,1.1506395499979194,0.9191355351926671,0.6481061483680024,4.105329277835919,0.8418043225749562,0.9963842539114091,-0.566047472031465,3.0927128631856373,0.8804803264068664,-0.3291314594756453,-0.05392643070728478,0.8418043225749562,0.024466452206715977,0.14186560484493307,0.9963842539114091,1.034978100199594,-0.6452217131559657,1.2276486948314262,0.06362460524619651,3.955897930278428,0.06362460524619651,0.024466452206715977,0.6093015947704223,1.4582167193470499,0.6868888119615674
| 3,643
|
ubiquitin-protein ligase
| 35
| 75
| 3.693287
| 0.000221
|
Q8TEB1,Q8N806,O15344,Q9UBS8,Q7Z7E8,Q9H000,Q12834,Q8TBC4,Q86UK7,O43164,Q9Y263,Q96J02,Q93034,Q96PU5,Q16763,Q9UJX3,Q8TDB6,P68036,Q149N8,Q9NT62,P19474,P61088,Q13618,Q14139,Q9ULT8,P38398,Q9UII4,Q7Z6Z7,Q86VP6,Q15386,Q9Y4X5,A0AVT1,Q13564,O95352,O95155
|
Functions
|
Panther Protein class
|
panther_protein_class
|
399,789,498,529,138,676,509,956,274,650,976,305,845,323,58,64,203,938,584,218,574,827,582,211,756,339,496,630,739,369,911,604,735,233,864
|
604,498,650,1396,2471,2771,1397,864,233,1666,1465,1321,574,1612,2032,339,935,1623,827,1826,938,1269,509,1749,1487,735,1072,1693,582,2184,211,2429,584,369,58,1495,1350,2436,2437,3267,630,138,274,739,789,956,203,399,1846,845,305,323,1848,2327,1515,1998,1150,676,1934,3464,1655,218,2271,3357,1781,529,1381,496,2390,64,756,1305,976,2872,911
|
0.7643892266436848,0.8804803264068664,0.7256497757208881,0.22000783347747066,-0.4080005745537821,-0.605622205270541,0.22000783347747066,0.5316260405382865,1.3045804843879147,0.06362460524619651,0.18094894503092676,0.25904250556837555,0.8031073486334814,0.10275757306645614,-0.132423168996273,1.1121055878194461,0.49275464296587623,0.10275757306645614,0.5704749577465287,-0.014717140094497816,0.49275464296587623,0.2980531923406561,0.8804803264068664,0.024466452206715977,0.18094894503092676,0.6481061483680024,0.4149435883630969,0.06362460524619651,0.8031073486334814,-0.21102594097074423,1.3814361078072093,-0.36855296551083955,0.8031073486334814,1.073551824278558,2.2981519715712917,0.18094894503092676,0.25904250556837555,-0.36855296551083955,-0.36855296551083955,-1.0425353636919736,0.7643892266436848,1.6498473485953888,1.2276486948314262,0.6481061483680024,0.6093015947704223,0.49275464296587623,1.4198357192420223,1.034978100199594,-0.014717140094497816,0.5704749577465287,1.1891538675508655,1.1506395499979194,-0.014717140094497816,-0.2897362923580755,0.18094894503092676,-0.09316168383661999,0.3760035130473384,0.7256497757208881,-0.05392643070728478,-1.3620283590937732,0.10275757306645614,1.3814361078072093,-0.2503677045331832,-1.1621798444446965,0.024466452206715977,0.8804803264068664,0.25904250556837555,0.9191355351926671,-0.3291314594756453,2.222128940045359,0.6481061483680024,0.2980531923406561,0.49275464296587623,-0.6452217131559657,0.5316260405382865
| 3,643
|
Protein kinase
| 35
| 101
| 3.687447
| 0.000227
|
Q9BUB5,Q16539,Q8IW41,Q9H4A3,Q13546,P51812,P49761,Q14012,P11802,Q8TD19,Q9BVS4,Q96GX5,Q96SB4,Q8WZ42,Q9BRS2,O14976,P51617,Q00535,Q9Y3S1,Q15418,O14757,O15111,O14733,O43683,P46020,Q86UE8,Q86Y07,P33981,O14920,O14965,P49841,P54646,O60566,Q96KB5,Q00534
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
403,394,10,11,257,13,506,510,142,552,278,23,555,427,430,408,290,176,196,61,65,66,183,67,310,317,487,208,221,468,475,477,356,520,242
|
183,65,3174,221,1388,468,408,66,686,67,356,1536,3505,687,2091,2289,1120,2411,3060,1317,142,3367,3542,2606,1248,1249,1812,3605,1057,1121,3183,1815,208,1126,1476,1969,310,538,1259,1002,506,1005,475,1336,290,13,1684,2842,477,1899,1742,1627,242,176,1012,1423,1560,2117,2183,1632,2688,779,257,878,2425,510,2430,3035,833,2801,61,1634,1279,394,1020,2122,2367,1141,317,487,741,10,552,427,2754,23,520,2376,1924,555,1772,1578,430,403,278,1710,11,1718,1784,809,196
|
1.4582167193470499,2.184093386153049,-0.9628854457235239,1.3430177439240172,0.22000783347747066,0.9191355351926671,0.9963842539114091,2.146041665971875,0.6868888119615674,2.146041665971875,1.073551824278558,0.14186560484493307,-1.5222926203028688,0.6868888119615674,-0.17171116116859408,-0.2897362923580755,0.3760035130473384,-0.36855296551083955,-0.8435837193418066,0.25904250556837555,1.611557358304762,-1.2021058814321368,-1.7230890308303868,-0.48697317960573294,0.2980531923406561,0.2980531923406561,-0.014717140094497816,-2.4905544051565287,0.4149435883630969,0.3760035130473384,-0.9628854457235239,-0.014717140094497816,1.3814361078072093,0.3760035130473384,0.18094894503092676,-0.09316168383661999,1.1506395499979194,0.8418043225749562,0.2980531923406561,0.4538605613386647,0.8804803264068664,0.4538605613386647,0.9191355351926671,0.25904250556837555,1.1891538675508655,3.618950764638868,0.06362460524619651,-0.6452217131559657,0.9191355351926671,-0.05392643070728478,0.024466452206715977,0.10275757306645614,1.3045804843879147,1.496579247199708,0.4538605613386647,0.22000783347747066,0.14186560484493307,-0.17171116116859408,-0.21102594097074423,0.10275757306645614,-0.5264977250215082,0.6093015947704223,1.266124183862369,0.5316260405382865,-0.36855296551083955,0.8804803264068664,-0.36855296551083955,-0.8038633863877657,0.5704749577465287,-0.605622205270541,2.222128940045359,0.10275757306645614,0.2980531923406561,1.034978100199594,0.4538605613386647,-0.17171116116859408,-0.3291314594756453,0.3760035130473384,1.1506395499979194,0.9191355351926671,0.6481061483680024,4.105329277835919,0.8418043225749562,0.9963842539114091,-0.566047472031465,3.0927128631856373,0.8804803264068664,-0.3291314594756453,-0.05392643070728478,0.8418043225749562,0.024466452206715977,0.14186560484493307,0.9963842539114091,1.034978100199594,1.2276486948314262,0.06362460524619651,3.955897930278428,0.06362460524619651,0.024466452206715977,0.6093015947704223,1.4582167193470499
| 3,643
|
Protein kinase-like domain superfamily [IPR011009]
| 35
| 101
| 3.665304
| 0.000247
|
Q9BUB5,Q16539,Q8IW41,Q9H4A3,Q13546,P51812,P49761,Q14012,P11802,Q8TD19,Q9BVS4,Q96GX5,Q96SB4,Q9UBF8,Q8WZ42,Q9BRS2,O14976,P51617,Q00535,Q9Y3S1,Q15418,O14757,O15111,O14733,O43683,Q86UE8,Q86Y07,P33981,O14920,O14965,P49841,P54646,O60566,Q96KB5,Q00534
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
403,394,10,11,257,13,506,510,142,552,278,23,555,159,427,430,408,290,176,196,61,65,66,183,67,317,487,208,221,468,475,477,356,520,242
|
1308,183,65,221,1388,468,408,66,686,67,356,1536,3505,687,2091,2289,1120,2411,3060,1317,142,3367,3542,2606,1248,1249,1812,3605,1057,1121,3183,1815,208,1126,1476,1969,3337,538,1259,1002,506,1005,475,1336,290,13,1684,477,1742,1627,242,176,1012,1423,1560,2117,2183,1632,2688,779,257,878,2425,510,833,2801,61,1634,1279,394,1020,2122,2367,3039,1141,317,487,741,10,3155,552,427,2754,23,520,2376,1924,555,1772,1578,430,403,278,1710,11,1718,159,1784,809,196,2083
|
0.25904250556837555,1.4582167193470499,2.184093386153049,1.3430177439240172,0.22000783347747066,0.9191355351926671,0.9963842539114091,2.146041665971875,0.6868888119615674,2.146041665971875,1.073551824278558,0.14186560484493307,-1.5222926203028688,0.6868888119615674,-0.17171116116859408,-0.2897362923580755,0.3760035130473384,-0.36855296551083955,-0.8435837193418066,0.25904250556837555,1.611557358304762,-1.2021058814321368,-1.7230890308303868,-0.48697317960573294,0.2980531923406561,0.2980531923406561,-0.014717140094497816,-2.4905544051565287,0.4149435883630969,0.3760035130473384,-0.9628854457235239,-0.014717140094497816,1.3814361078072093,0.3760035130473384,0.18094894503092676,-0.09316168383661999,-1.1621798444446965,0.8418043225749562,0.2980531923406561,0.4538605613386647,0.8804803264068664,0.4538605613386647,0.9191355351926671,0.25904250556837555,1.1891538675508655,3.618950764638868,0.06362460524619651,0.9191355351926671,0.024466452206715977,0.10275757306645614,1.3045804843879147,1.496579247199708,0.4538605613386647,0.22000783347747066,0.14186560484493307,-0.17171116116859408,-0.21102594097074423,0.10275757306645614,-0.5264977250215082,0.6093015947704223,1.266124183862369,0.5316260405382865,-0.36855296551083955,0.8804803264068664,0.5704749577465287,-0.605622205270541,2.222128940045359,0.10275757306645614,0.2980531923406561,1.034978100199594,0.4538605613386647,-0.17171116116859408,-0.3291314594756453,-0.8038633863877657,0.3760035130473384,1.1506395499979194,0.9191355351926671,0.6481061483680024,4.105329277835919,-0.9230949351912728,0.8418043225749562,0.9963842539114091,-0.566047472031465,3.0927128631856373,0.8804803264068664,-0.3291314594756453,-0.05392643070728478,0.8418043225749562,0.024466452206715977,0.14186560484493307,0.9963842539114091,1.034978100199594,1.2276486948314262,0.06362460524619651,3.955897930278428,0.06362460524619651,1.5732494325114137,0.024466452206715977,0.6093015947704223,1.4582167193470499,-0.132423168996273
| 3,643
|
Antigen processing ubiquitination proteasome degradation
| 52
| 105
| 3.631109
| 0.000282
|
P61289,Q92530,Q96ME1,Q14145,Q7Z7E8,Q14999,Q9UBS8,P28070,Q06323,Q12834,Q9UL46,O00233,Q8TBC4,P25789,O43164,Q96J02,P52888,Q93034,P49427,Q96PU5,Q9Y3I1,Q9C0C9,Q9Y4B6,Q16763,Q9UJX3,Q8TDB6,P55786,P68036,Q13200,Q63HN8,Q13867,P61081,P19474,P61088,Q14139,Q13618,Q9ULT8,Q9UII4,O75832,Q7Z6Z7,P51665,Q15386,Q15345,P60900,Q8NEZ5,A0AVT1,O00487,Q13309,Q15369,O43242,O95352,P25786
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
129,791,264,6,138,884,529,255,256,509,811,381,956,770,650,305,540,845,418,323,860,326,716,58,64,203,311,938,943,315,698,935,574,827,211,582,756,496,335,630,728,369,368,731,111,604,606,733,886,862,233,865
|
604,1597,2219,381,606,1112,650,862,335,2471,2771,233,1666,2409,2027,574,994,1612,865,1407,1188,770,1323,255,2228,1473,1678,2032,2298,2415,2235,418,1335,2358,728,540,1261,311,1413,731,935,1623,827,129,1201,2110,1481,1826,938,1269,256,509,1487,943,733,1072,1693,582,698,211,6,2429,1273,884,1017,368,886,2431,369,58,1495,1350,2436,315,2746,3267,630,138,111,956,203,791,1846,845,305,264,323,1577,2068,326,1150,1934,529,496,3527,2390,64,1786,2655,811,756,1305,1861,860,716
|
0.7643892266436848,0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,0.7256497757208881,0.5316260405382865,1.1121055878194461,-0.4080005745537821,-0.605622205270541,1.3045804843879147,0.06362460524619651,-0.36855296551083955,-0.132423168996273,0.8031073486334814,0.4538605613386647,0.10275757306645614,0.5316260405382865,0.22000783347747066,0.3370401206025548,0.6093015947704223,0.25904250556837555,1.266124183862369,-0.2503677045331832,0.18094894503092676,0.06362460524619651,-0.132423168996273,-0.2897362923580755,-0.36855296551083955,-0.2503677045331832,0.9963842539114091,0.25904250556837555,-0.3291314594756453,0.6481061483680024,0.8418043225749562,0.2980531923406561,1.1506395499979194,0.22000783347747066,0.6481061483680024,0.49275464296587623,0.10275757306645614,0.5704749577465287,1.688119532883408,0.3370401206025548,-0.17171116116859408,0.18094894503092676,-0.014717140094497816,0.49275464296587623,0.2980531923406561,1.266124183862369,0.8804803264068664,0.18094894503092676,0.49275464296587623,0.6481061483680024,0.4149435883630969,0.06362460524619651,0.8031073486334814,0.6868888119615674,1.3814361078072093,4.775434762616395,-0.36855296551083955,0.2980531923406561,0.5316260405382865,0.4538605613386647,1.073551824278558,0.5316260405382865,-0.36855296551083955,1.073551824278558,2.2981519715712917,0.18094894503092676,0.25904250556837555,-0.36855296551083955,1.1506395499979194,-0.566047472031465,-1.0425353636919736,0.7643892266436848,1.6498473485953888,1.764610992500279,0.49275464296587623,1.4198357192420223,0.6093015947704223,-0.014717140094497816,0.5704749577465287,1.1891538675508655,1.266124183862369,1.1506395499979194,0.14186560484493307,-0.132423168996273,1.1506395499979194,0.3760035130473384,-0.05392643070728478,0.8804803264068664,0.9191355351926671,-1.6025499029064922,-0.3291314594756453,2.222128940045359,0.024466452206715977,-0.48697317960573294,0.6093015947704223,0.6481061483680024,0.2980531923406561,-0.014717140094497816,0.5704749577465287,0.6868888119615674
| 3,643
|
Zinc finger, RING-type, conserved site [IPR017907]
| 14
| 23
| 3.56248
| 0.000367
|
Q8NCN4,O15344,Q8TDB6,Q14527,Q149N8,Q99590,Q9UPN9,P19474,P22681,O75150,Q12933,Q99728,P38398,Q9UBS8
|
Sequence
|
InterPro Conserved site
|
interpro_conserved_site
|
227,498,203,258,584,76,644,574,143,22,455,556,339,529
|
1662,498,22,1666,1321,574,143,339,1197,455,1016,258,584,2995,227,203,1848,2327,76,556,676,529,644
|
0.06362460524619651,0.8804803264068664,3.0927128631856373,0.06362460524619651,0.25904250556837555,0.8031073486334814,1.611557358304762,1.1121055878194461,0.3370401206025548,0.9577701211888938,0.4538605613386647,1.266124183862369,0.8031073486334814,-0.7641668235232126,1.3430177439240172,1.4198357192420223,-0.014717140094497816,-0.2897362923580755,2.0698892959609982,0.8418043225749562,0.7256497757208881,0.8804803264068664,0.7643892266436848
| 3,643
|
Ubiquitin mediated proteolysis
| 29
| 56
| 3.527992
| 0.000419
|
O15344,Q14145,Q7Z7E8,Q14999,Q12834,P22681,Q8TBC4,P98170,Q96J02,P29372,P49427,Q93034,Q96PU5,Q9C0C9,Q16763,Q8N2W9,Q9UJX3,P68036,P61088,Q13618,Q14139,P38398,Q7Z6Z7,Q15386,Q13309,A0AVT1,Q15369,Q9NR09,O95155
|
Processes and pathways
|
KEGG Pathways
|
msigdb_kegg
|
498,6,138,884,509,143,956,664,305,414,418,845,323,326,58,191,64,938,827,582,211,339,630,369,733,604,886,528,864
|
604,498,3588,2021,1397,864,2409,1612,143,414,2032,339,418,1413,935,1623,827,1826,938,664,1269,509,1487,733,1072,1693,582,2184,211,6,2429,884,886,2431,369,1982,58,1495,630,138,191,956,845,305,323,326,1934,528,1781,1381,2390,64,1786,2655,2967,1305
|
0.7643892266436848,0.8804803264068664,-2.1261701689752903,-0.132423168996273,0.22000783347747066,0.5316260405382865,-0.36855296551083955,0.10275757306645614,1.611557358304762,0.9963842539114091,-0.132423168996273,1.1121055878194461,0.9963842539114091,0.22000783347747066,0.49275464296587623,0.10275757306645614,0.5704749577465287,-0.014717140094497816,0.49275464296587623,0.7256497757208881,0.2980531923406561,0.8804803264068664,0.18094894503092676,0.6481061483680024,0.4149435883630969,0.06362460524619651,0.8031073486334814,-0.21102594097074423,1.3814361078072093,4.775434762616395,-0.36855296551083955,0.5316260405382865,0.5316260405382865,-0.36855296551083955,1.073551824278558,-0.09316168383661999,2.2981519715712917,0.18094894503092676,0.7643892266436848,1.6498473485953888,1.4582167193470499,0.49275464296587623,0.5704749577465287,1.1891538675508655,1.1506395499979194,1.1506395499979194,-0.05392643070728478,0.8804803264068664,0.024466452206715977,0.25904250556837555,-0.3291314594756453,2.222128940045359,0.024466452206715977,-0.48697317960573294,-0.724494224850264,0.2980531923406561
| 3,643
|
Cysteine protease
| 27
| 51
| 3.52234
| 0.000428
|
O94782,Q96RU2,P17655,P45974,Q8TC07,Q6GQQ9,Q9NVG8,Q9UDY8,Q14674,P55212,Q01804,Q8NB14,Q9GZR1,O15484,P40818,P08243,O60343,P17812,Q9Y4E8,P42574,Q96K76,P27708,P49915,Q9Y4P1,Q14694,P51784,Q96FW1
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
128,133,8,504,277,298,562,563,294,661,291,320,77,568,446,84,207,336,99,223,636,472,476,127,365,238,402
|
568,207,128,1665,2223,84,8,336,3310,472,446,223,504,476,238,1198,872,661,1066,291,1130,876,3529,698,294,365,948,2743,1079,298,320,842,2256,277,3447,2563,3293,1573,402,636,133,1444,77,1225,562,1101,563,1169,99,127,1790
|
0.8031073486334814,1.3814361078072093,1.688119532883408,0.06362460524619651,-0.2503677045331832,1.9936709544036635,4.1799723104062085,1.1121055878194461,-1.1222759669079696,0.9191355351926671,0.9577701211888938,1.3430177439240172,0.8804803264068664,0.9191355351926671,1.3045804843879147,0.3370401206025548,0.5316260405382865,0.7256497757208881,0.4149435883630969,1.1891538675508655,0.3760035130473384,0.5316260405382865,-1.6427093252343525,0.6868888119615674,1.1891538675508655,1.073551824278558,0.49275464296587623,-0.566047472031465,0.4149435883630969,1.1891538675508655,1.1506395499979194,0.5704749577465287,-0.2503677045331832,1.2276486948314262,-1.3220153104882866,-0.44747405503507703,-1.0823944165347616,0.14186560484493307,1.034978100199594,0.7643892266436848,1.688119532883408,0.22000783347747066,2.0698892959609982,0.3370401206025548,0.8418043225749562,0.4149435883630969,0.8418043225749562,0.3760035130473384,1.8410327378570173,1.7263740388712179,0.024466452206715977
| 3,643
|
Regulation of ubiquitin protein transferase activity
| 11
| 26
| 3.521948
| 0.000428
|
O00429,Q13526,Q8TDB6,Q12834,P61927,Q9BTE7,O60566,O95816,Q96GX5,Q16763,Q9UL15
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
97,130,203,509,541,113,356,357,23,58,29
|
97,1729,356,357,992,2102,1684,1262,827,541,1898,1482,937,2045,1826,938,509,580,130,58,203,23,1444,113,29,1305
|
1.8410327378570173,0.024466452206715977,1.073551824278558,1.073551824278558,0.4538605613386647,-0.17171116116859408,0.06362460524619651,0.2980531923406561,0.5704749577465287,0.8418043225749562,-0.05392643070728478,0.18094894503092676,0.49275464296587623,-0.132423168996273,-0.014717140094497816,0.49275464296587623,0.8804803264068664,0.8031073486334814,1.688119532883408,2.2981519715712917,1.4198357192420223,3.0927128631856373,0.22000783347747066,1.764610992500279,2.828581783531681,0.2980531923406561
| 3,643
|
Other group
| 11
| 21
| 3.515096
| 0.00044
|
O15111,O43683,O14965,O14920,Q9H4A3,Q86UE8,O14976,O60566,Q96KB5,Q9Y3S1,P33981
|
Drugs and Diseases
|
Pharos Drug Target Ontology
|
pharos_dto
|
66,67,468,221,11,317,408,356,520,196,208
|
221,468,408,66,67,356,1248,208,1684,2122,2367,317,552,2754,520,2376,1772,11,1784,809,196
|
1.3430177439240172,0.9191355351926671,0.9963842539114091,2.146041665971875,2.146041665971875,1.073551824278558,0.2980531923406561,1.3814361078072093,0.06362460524619651,-0.17171116116859408,-0.3291314594756453,1.1506395499979194,0.8418043225749562,-0.566047472031465,0.8804803264068664,-0.3291314594756453,0.024466452206715977,3.955897930278428,0.024466452206715977,0.6093015947704223,1.4582167193470499
| 3,643
|
Papain-like cysteine peptidase superfamily [IPR038765]
| 15
| 28
| 3.514993
| 0.00044
|
O94782,Q8NB14,Q9Y4E8,Q96RU2,P17655,P45974,Q9GZR1,O15484,P40818,Q01804,Q86UV5,Q9Y4P1,Q14694,P51784,Q96FW1
|
Sequence
|
InterPro Superfamily
|
interpro_homologous_superfamily
|
128,320,99,133,8,504,77,568,446,291,275,127,365,238,402
|
568,128,1665,2223,8,446,504,238,1198,291,698,365,2743,275,320,3447,1292,1573,402,636,133,77,1450,1101,1166,99,127,1790
|
0.8031073486334814,1.688119532883408,0.06362460524619651,-0.2503677045331832,4.1799723104062085,0.9577701211888938,0.8804803264068664,1.3045804843879147,0.3370401206025548,1.1891538675508655,0.6868888119615674,1.073551824278558,-0.566047472031465,1.2276486948314262,1.1506395499979194,-1.3220153104882866,0.2980531923406561,0.14186560484493307,1.034978100199594,0.7643892266436848,1.688119532883408,2.0698892959609982,0.22000783347747066,0.4149435883630969,0.3760035130473384,1.8410327378570173,1.7263740388712179,0.024466452206715977
| 3,643
|
Neddylation
| 35
| 81
| 3.509875
| 0.000448
|
Q8TEB1,P61289,Q92530,Q96ME1,Q14145,Q14999,P28070,Q06323,Q9UL46,O00233,Q8TBC4,P25789,O94888,Q93034,Q9Y3I1,Q9NZJ0,Q9Y5A7,Q13200,P61081,Q7L5N1,Q13618,Q86X83,O75832,Q86VP6,P51665,Q15345,Q9BTE7,P60900,Q8NEZ5,Q13309,O00487,Q13564,Q15369,O43242,P25786
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
399,129,791,264,6,884,255,256,811,381,956,770,285,845,860,60,206,943,935,486,582,740,335,739,728,368,113,731,111,733,606,735,886,862,865
|
1597,2219,381,606,1112,862,1238,335,285,2027,994,865,1407,1188,770,1323,255,2228,1473,2298,2415,2235,1335,2358,728,1261,731,935,1064,129,3069,3185,1201,2110,1481,1826,256,1750,943,733,735,1072,1693,582,2184,6,1273,884,1017,2694,368,886,2431,1982,1348,2437,486,739,740,111,956,399,791,1367,845,264,1577,2068,1649,1373,113,1933,1451,2338,60,2965,811,1861,1162,860,206
|
0.10275757306645614,-0.2503677045331832,1.034978100199594,0.7643892266436848,0.3760035130473384,0.5316260405382865,0.2980531923406561,1.1121055878194461,1.1891538675508655,-0.132423168996273,0.4538605613386647,0.5316260405382865,0.22000783347747066,0.3370401206025548,0.6093015947704223,0.25904250556837555,1.266124183862369,-0.2503677045331832,0.18094894503092676,-0.2897362923580755,-0.36855296551083955,-0.2503677045331832,0.25904250556837555,-0.3291314594756453,0.6481061483680024,0.2980531923406561,0.6481061483680024,0.49275464296587623,0.4149435883630969,1.688119532883408,-0.8435837193418066,-0.9628854457235239,0.3370401206025548,-0.17171116116859408,0.18094894503092676,-0.014717140094497816,1.266124183862369,0.024466452206715977,0.49275464296587623,0.6481061483680024,0.6481061483680024,0.4149435883630969,0.06362460524619651,0.8031073486334814,-0.21102594097074423,4.775434762616395,0.2980531923406561,0.5316260405382865,0.4538605613386647,-0.5264977250215082,1.073551824278558,0.5316260405382865,-0.36855296551083955,-0.09316168383661999,0.25904250556837555,-0.36855296551083955,0.9191355351926671,0.6481061483680024,0.6481061483680024,1.764610992500279,0.49275464296587623,1.034978100199594,0.6093015947704223,0.25904250556837555,0.5704749577465287,1.266124183862369,0.14186560484493307,-0.132423168996273,0.10275757306645614,0.25904250556837555,1.764610992500279,-0.05392643070728478,0.22000783347747066,-0.2897362923580755,2.2601484336349698,-0.724494224850264,0.6093015947704223,-0.014717140094497816,0.3760035130473384,0.5704749577465287,1.4198357192420223
| 3,643
|
Metaphase anaphase transition of cell cycle
| 16
| 35
| 3.469935
| 0.000521
|
Q99741,Q96EA4,O43683,Q9Y6A5,Q14674,O43670,O43264,Q15398,Q9Y6G9,O60566,Q9BVS4,P14635,Q13257,P33981,Q13618,Q9UJX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
228,401,67,602,294,470,441,370,647,356,278,108,580,208,582,64
|
441,2588,470,67,1729,2828,356,612,2092,108,2032,208,2677,1684,1487,3189,580,582,294,370,1209,1211,794,401,2754,228,278,1934,1155,2390,64,1786,2655,602,647
|
0.9577701211888938,-0.48697317960573294,0.9191355351926671,2.146041665971875,0.024466452206715977,-0.6452217131559657,1.073551824278558,0.7643892266436848,-0.17171116116859408,1.764610992500279,-0.132423168996273,1.3814361078072093,-0.5264977250215082,0.06362460524619651,0.18094894503092676,-0.9628854457235239,0.8031073486334814,0.8031073486334814,1.1891538675508655,1.073551824278558,0.3370401206025548,0.3370401206025548,0.6093015947704223,1.034978100199594,-0.566047472031465,1.3430177439240172,1.2276486948314262,-0.05392643070728478,0.3760035130473384,-0.3291314594756453,2.222128940045359,0.024466452206715977,-0.48697317960573294,0.8031073486334814,0.7643892266436848
| 3,643
|
cysteine protease
| 18
| 32
| 3.469692
| 0.000521
|
O94782,Q8NB14,Q9Y4E8,Q96RU2,Q14674,P17655,P45974,Q9GZR1,O15484,P40818,Q01804,Q86UV5,Q9Y4P1,Q14694,P51784,Q6GQQ9,Q96FW1,Q9UDY8
|
Functions
|
Panther Protein class
|
panther_protein_class
|
128,320,99,133,294,8,504,77,568,446,291,275,127,365,238,298,402,563
|
568,128,1665,2223,8,446,504,238,1198,291,3529,698,294,365,2743,298,275,320,3447,3293,1292,1573,402,636,133,77,1101,563,1166,99,127,1790
|
0.8031073486334814,1.688119532883408,0.06362460524619651,-0.2503677045331832,4.1799723104062085,0.9577701211888938,0.8804803264068664,1.3045804843879147,0.3370401206025548,1.1891538675508655,-1.6427093252343525,0.6868888119615674,1.1891538675508655,1.073551824278558,-0.566047472031465,1.1891538675508655,1.2276486948314262,1.1506395499979194,-1.3220153104882866,-1.0823944165347616,0.2980531923406561,0.14186560484493307,1.034978100199594,0.7643892266436848,1.688119532883408,2.0698892959609982,0.4149435883630969,0.8418043225749562,0.3760035130473384,1.8410327378570173,1.7263740388712179,0.024466452206715977
| 3,643
|
Response of eif2ak4 gcn2 to amino acid deficiency
| 48
| 77
| 3.457019
| 0.000546
|
P62266,P83881,P62753,P62917,P46782,P42766,P62701,P63173,P60866,P39023,P35268,P08708,P20042,P62857,P27635,Q9Y3U8,Q92616,P62750,P62277,P62847,P62269,P46778,P61927,P61254,P18621,P47914,P63220,P62899,P46779,P61513,P62841,P18077,P61247,P08243,P83731,P62244,Q02543,Q02878,P62854,P25398,P62241,P46776,P49207,P36578,P62910,P15880,P61313,P84098
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
621,1011,622,1266,869,503,1265,508,1262,1001,1258,1399,1250,271,771,566,1219,1419,1417,662,1416,288,541,1200,1184,824,452,451,1193,696,937,820,1066,84,578,1067,830,831,344,337,1340,473,1333,1329,241,992,240,121
|
1877,3179,2476,84,1399,2412,992,820,2480,1184,1250,1613,337,1881,771,1814,2097,1258,1329,2611,1001,1475,1968,503,473,2102,288,1193,1737,869,2175,824,1333,1822,1262,1066,1200,240,1896,696,541,1898,1340,1067,2111,1415,621,1416,1417,2487,2044,1265,1419,622,1482,937,662,1741,344,271,1624,1625,451,2112,241,2045,1266,508,452,578,1011,121,830,831,2048,1219,566
|
-0.05392643070728478,-0.9628854457235239,-0.4080005745537821,1.9936709544036635,0.22000783347747066,-0.36855296551083955,0.4538605613386647,0.5704749577465287,-0.4080005745537821,0.3370401206025548,0.2980531923406561,0.10275757306645614,1.1121055878194461,-0.05392643070728478,0.6093015947704223,-0.014717140094497816,-0.17171116116859408,0.2980531923406561,0.25904250556837555,-0.48697317960573294,0.4538605613386647,0.18094894503092676,-0.09316168383661999,0.8804803264068664,0.9191355351926671,-0.17171116116859408,1.1891538675508655,0.3370401206025548,0.024466452206715977,0.5316260405382865,-0.21102594097074423,0.5704749577465287,0.25904250556837555,-0.014717140094497816,0.2980531923406561,0.4149435883630969,0.3370401206025548,1.3045804843879147,-0.05392643070728478,0.6868888119615674,0.8418043225749562,-0.05392643070728478,0.25904250556837555,0.4149435883630969,-0.17171116116859408,0.22000783347747066,0.7643892266436848,0.22000783347747066,0.22000783347747066,-0.4080005745537821,-0.132423168996273,0.2980531923406561,0.22000783347747066,0.7643892266436848,0.18094894503092676,0.49275464296587623,0.7256497757208881,0.024466452206715977,1.1121055878194461,1.2276486948314262,0.10275757306645614,0.10275757306645614,0.9577701211888938,-0.17171116116859408,1.3045804843879147,-0.132423168996273,0.2980531923406561,0.8804803264068664,0.9577701211888938,0.8031073486334814,0.4538605613386647,1.7263740388712179,0.5704749577465287,0.5704749577465287,-0.132423168996273,0.3370401206025548,0.8418043225749562
| 3,643
|
Cytoplasmic ribosomal proteins
| 47
| 75
| 3.437042
| 0.000588
|
P62266,P83881,P62753,P62917,P46782,P42766,P62701,P51812,P60866,P63173,P39023,P35268,P08708,P62857,P27635,Q9Y3U8,P62750,P62277,P62269,P62847,P46778,P61927,P61254,P18621,Q15418,P47914,P62899,P63220,P46779,P61513,P62841,P18077,P61247,P83731,P62244,Q02543,Q02878,P62854,P25398,P46776,P62241,P49207,P36578,P62910,P84098,P15880,P61313
|
Processes and pathways
|
WikiPathways
|
msigdb_wp
|
621,1011,622,1266,869,503,1265,13,1262,508,1001,1258,1399,271,771,566,1419,1417,1416,662,288,541,1200,1184,61,824,451,452,1193,696,937,820,1066,578,1067,830,831,344,337,473,1340,1333,1329,241,121,992,240
|
3179,2476,1399,2412,992,820,2480,1184,1613,337,1881,771,1814,2097,1258,1329,2611,1001,1475,503,473,2102,288,1193,1737,869,2175,824,1333,2785,1822,13,1262,1066,1200,240,1896,696,541,1898,1340,1067,2111,1415,621,1416,1417,2487,2044,1265,1419,622,1482,937,662,1741,344,271,1624,1625,451,2112,241,2045,1266,508,452,578,1011,121,830,831,2048,61,566
|
-0.9628854457235239,-0.4080005745537821,0.22000783347747066,-0.36855296551083955,0.4538605613386647,0.5704749577465287,-0.4080005745537821,0.3370401206025548,0.10275757306645614,1.1121055878194461,-0.05392643070728478,0.6093015947704223,-0.014717140094497816,-0.17171116116859408,0.2980531923406561,0.25904250556837555,-0.48697317960573294,0.4538605613386647,0.18094894503092676,0.8804803264068664,0.9191355351926671,-0.17171116116859408,1.1891538675508655,0.3370401206025548,0.024466452206715977,0.5316260405382865,-0.21102594097074423,0.5704749577465287,0.25904250556837555,-0.605622205270541,-0.014717140094497816,3.618950764638868,0.2980531923406561,0.4149435883630969,0.3370401206025548,1.3045804843879147,-0.05392643070728478,0.6868888119615674,0.8418043225749562,-0.05392643070728478,0.25904250556837555,0.4149435883630969,-0.17171116116859408,0.22000783347747066,0.7643892266436848,0.22000783347747066,0.22000783347747066,-0.4080005745537821,-0.132423168996273,0.2980531923406561,0.22000783347747066,0.7643892266436848,0.18094894503092676,0.49275464296587623,0.7256497757208881,0.024466452206715977,1.1121055878194461,1.2276486948314262,0.10275757306645614,0.10275757306645614,0.9577701211888938,-0.17171116116859408,1.3045804843879147,-0.132423168996273,0.2980531923406561,0.8804803264068664,0.9577701211888938,0.8031073486334814,0.4538605613386647,1.7263740388712179,0.5704749577465287,0.5704749577465287,-0.132423168996273,2.222128940045359,0.8418043225749562
| 3,643
|
Regulation of proteasomal protein catabolic process
| 21
| 79
| 3.402796
| 0.000667
|
P61289,Q14145,P45974,Q06323,Q9NZL4,P49069,O75150,Q9UL15,P48506,Q9Y5A7,Q86UE8,P82094,O75832,O14965,Q9GZU8,P49841,Q9GZP4,Q8NEZ5,O95816,Q96KB5,Q9UBS8
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
129,6,504,256,16,387,22,29,173,206,317,210,335,468,250,475,115,111,357,520,529
|
606,1867,468,1661,861,1600,1533,22,335,3588,2771,1665,1666,357,2773,1245,2225,1317,3542,2606,2027,1812,2298,2415,504,2036,173,1259,387,1005,475,3218,1684,1198,1549,3144,2739,1063,1623,129,1414,1201,2110,1481,2045,1010,1202,210,875,256,666,509,6,2431,1502,317,2196,111,791,2807,1846,1573,2454,520,1444,115,250,676,3407,16,2576,529,29,811,756,1305,911,206,1790
|
0.7643892266436848,-0.05392643070728478,0.9191355351926671,0.06362460524619651,0.5316260405382865,0.10275757306645614,0.14186560484493307,3.0927128631856373,1.1121055878194461,-2.1261701689752903,-0.605622205270541,0.06362460524619651,0.06362460524619651,1.073551824278558,-0.605622205270541,0.2980531923406561,-0.2503677045331832,0.25904250556837555,-1.7230890308303868,-0.48697317960573294,-0.132423168996273,-0.014717140094497816,-0.2897362923580755,-0.36855296551083955,0.8804803264068664,-0.132423168996273,1.496579247199708,0.2980531923406561,1.034978100199594,0.4538605613386647,0.9191355351926671,-1.0026989814648815,0.06362460524619651,0.3370401206025548,0.14186560484493307,-0.9230949351912728,-0.566047472031465,0.4149435883630969,0.10275757306645614,1.688119532883408,0.22000783347747066,0.3370401206025548,-0.17171116116859408,0.18094894503092676,-0.132423168996273,0.4538605613386647,0.3370401206025548,1.3814361078072093,0.5316260405382865,1.266124183862369,0.7256497757208881,0.8804803264068664,4.775434762616395,-0.36855296551083955,0.18094894503092676,1.1506395499979194,-0.21102594097074423,1.764610992500279,0.6093015947704223,-0.605622205270541,-0.014717140094497816,0.14186560484493307,-0.36855296551083955,0.8804803264068664,0.22000783347747066,1.764610992500279,1.3045804843879147,0.7256497757208881,-1.2420539127493266,3.3561603640456346,-0.44747405503507703,0.8804803264068664,2.828581783531681,0.6093015947704223,0.6481061483680024,0.2980531923406561,0.5316260405382865,1.4198357192420223,0.024466452206715977
| 3,643
|
Regulation of chromosome separation
| 16
| 37
| 3.389569
| 0.0007
|
Q99741,Q96EA4,O43683,Q9Y6A5,Q14674,O43670,O43264,Q15398,Q9Y6G9,O60566,Q9BVS4,P14635,Q13257,P33981,Q13618,Q9UJX3
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
228,401,67,602,294,470,441,370,647,356,278,108,580,208,582,64
|
441,2588,470,67,1729,2828,356,612,2092,108,1249,2032,208,2677,1684,1487,3189,580,582,294,2054,370,1209,1211,794,401,2754,228,278,1934,1155,2390,64,1786,2655,602,647
|
0.9577701211888938,-0.48697317960573294,0.9191355351926671,2.146041665971875,0.024466452206715977,-0.6452217131559657,1.073551824278558,0.7643892266436848,-0.17171116116859408,1.764610992500279,0.2980531923406561,-0.132423168996273,1.3814361078072093,-0.5264977250215082,0.06362460524619651,0.18094894503092676,-0.9628854457235239,0.8031073486334814,0.8031073486334814,1.1891538675508655,-0.132423168996273,1.073551824278558,0.3370401206025548,0.3370401206025548,0.6093015947704223,1.034978100199594,-0.566047472031465,1.3430177439240172,1.2276486948314262,-0.05392643070728478,0.3760035130473384,-0.3291314594756453,2.222128940045359,0.024466452206715977,-0.48697317960573294,0.8031073486334814,0.7643892266436848
| 3,643
|
Myd88 independent tlr4 cascade
| 24
| 30
| 3.320289
| 0.000899
|
Q04206,P28482,Q16539,Q13546,P51812,P49137,Q14738,Q06124,P46734,P51617,Q15418,O43318,O14733,P27361,O15111,P51452,Q13616,P09429,P61088,Q16644,Q8IV63,O14920,Q6SZW1,Q02750
|
Processes and pathways
|
Reactome Pathways
|
msigdb_reactome
|
623,1121,394,257,13,1002,296,293,538,290,61,686,183,1057,66,930,1072,818,827,1020,741,221,738,1012
|
183,221,66,686,2924,818,1057,1121,1408,1122,538,1002,930,290,13,827,1826,1012,623,293,257,1072,296,61,2894,394,1020,738,741,1784
|
1.4582167193470499,1.3430177439240172,2.146041665971875,0.6868888119615674,-0.724494224850264,0.5704749577465287,0.4149435883630969,0.3760035130473384,0.22000783347747066,0.3760035130473384,0.8418043225749562,0.4538605613386647,0.49275464296587623,1.1891538675508655,3.618950764638868,0.5704749577465287,-0.014717140094497816,0.4538605613386647,0.7643892266436848,1.1891538675508655,1.266124183862369,0.4149435883630969,1.1891538675508655,2.222128940045359,-0.6848457877873478,1.034978100199594,0.4538605613386647,0.6481061483680024,0.6481061483680024,0.024466452206715977
| 3,643
|
Double strand break repair via nonhomologous end joining
| 8
| 28
| 3.305588
| 0.000948
|
Q5UIP0,Q8TDB6,Q96FZ2,P49916,Q92889,Q9BRJ7,Q9BUR4,Q00613
|
Processes and pathways
|
GO Biological process
|
msigdb_gobp
|
2,203,105,7,75,181,148,272
|
2154,606,1538,818,1400,2777,1320,2226,309,1125,7,3027,1895,1627,272,2308,1071,2,3318,203,75,105,2710,181,148,1527,2967,2764
|
-0.21102594097074423,0.7643892266436848,0.14186560484493307,0.5704749577465287,0.22000783347747066,-0.605622205270541,0.25904250556837555,-0.2503677045331832,1.1506395499979194,0.3760035130473384,4.291847410390771,-0.8038633863877657,-0.05392643070728478,0.10275757306645614,1.2276486948314262,-0.2897362923580755,0.4149435883630969,6.692085953552384,-1.1222759669079696,1.4198357192420223,2.0698892959609982,1.8028305179868904,-0.5264977250215082,1.496579247199708,1.611557358304762,0.18094894503092676,-0.724494224850264,-0.566047472031465
| 3,643
|
Subsets and Splits
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