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Muscle relaxant that can be used in a patient with high serum bilirubin of 6.0 and serum creatinine of 4.5 mg/ dL?
Ans. a. Atracurium (Ref: Goodman Gilman 12/e p264; Morgan 4/e p221; Lee 13/e p191,192)Muscle relaxant that can be used in a patient with high serum bilirubin of 6.0 and serum creatinine of 4.5 mg/dL is Atracurium because of unique metabolism independent of hepatic and renal functions and ensured degradation.AtracuriumA...
1
Atracurium
Vecuronium
Pancuronium
Mivacurium
Anaesthesia
Non-depolarising Neuromuscular Blocking Agents
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single
Helix in a finger spring for mesial movement lies
null
3
Mesial to the tong axis of the tooth
Distal to the Long axis of the tooth
In line to the long axis of the tooth
Perpendicular to the long axis of the tooth
Dental
null
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single
Diuretic causing gynaecomastia is -
Ans. is 'b' i.e., Spironolactone Drugs causing gynecomastia* Calcium channel antagonist* Isoniazide* Reserpine* Clomiphene* Ketoconazole* Digitalis* Methyldopa* Estrogens* Testosterone* Flutamide* Phenytoin* Cimetidine* Ethionamide* Griseofulvin* Goserelin* Griseofulvin* Spironolactone* Cyprotenrone acetate Note: Cimet...
2
Lubiprostone
Spironolactone
Cimetidine
Chlorthalidone
Pharmacology
Diuretic
cecbe051-d079-4542-864b-35c2af750b76
single
DNA foot printing is used to detect
Techniques of detection of DNA-Protein interaction : DNA footprinting Yeast one-hybrid system Electrophoretic mobility shift assay (EMSA)
4
Single nucleotide polymorphisms
Variable number of tandem repeats
Parent of origin of the child
DNA-protein interaction
Biochemistry
Techniques in molecular biology
53e13be6-87c8-4229-b3b3-02e714bfb0c1
single
Replacement dose of thyroxine is
• Daily replacement dose of thyroxine: 1.6 μg/Kg body weight (0.1-0.15 gm) . • For TSH suppression (in PTC and FTC), dose of thyroxine: 2.7 μg/Kg body weight.
1
0.1 - 0.2 mg
0.3 - 0.4 mg
1 - 2 mg
3 - 4 mg
Surgery
null
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single
Insulin of choice in a patient with Diabetic ketoacidosis?
Regular Insulin is short acting formulation given intravenously in cases of Diabetic ketoacidosis.
4
Lispro
Deterimer
Aspart
Regular Insulin
Pharmacology
null
7e183c01-dddf-4ed8-b81e-407133dfaac5
single
Which radioisotope of Iodine is used in the treatment of hypehyroidism?
Iodine 131 when taken up by thyroid gland result in destruction of the trapping cell and cells in close proximity. Because thyroid gland has extremely high affinity for iodine compared to other tissues, radioactive iodine results in selective ablation of thyroid tissue. Ref: Diseases of the Thyroid in Childhood and Ado...
3
I123
I125
I131
I132
Radiology
null
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single
Virus causing cervical cancer in the ectocervix -
Ans. is 'a' i.e., HPV 16 Carcinoma cervixo The m/c etiological factor associated with cancer cervix is Human Papillomavirus (HPV).o HPV is epitheliotropic.o High-risk HPVInclude 16, 18, 31, 33, 35, 39. 45, 52, 56, 58, 59, 68.o Low-risk HPV associated with genital warts are subtype 6 and 11.o Almost 80% women are infect...
1
HPV16
HPV17
HPV11
HPV19
Unknown
null
1da2fef4-a77d-4f3e-b396-db576d0785d8
single
The commonest systemic abnormality associated with renal cell carcinoma Is -
The preoperative erythrocyte sedimentation rate is an independent prognostic factor in renal cell carcinoma. An elevated erythrocyte sedimentation rate (ESR) repoedly has been associated with a poor prognosis among patients with RCC, but the ESR is not incorporated into existing nomograms Ref Harrison20th edition pg 28...
3
Hypeension
Polycythemia
Elevated ESR
Pyrexia
Medicine
Kidney
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single
Which hormone is not affected by menstrual cycle -
Ans. is 'd' i.e., Prolactin o Prolactin levels do not fluctuate much during the menstrual cycle.
4
Estrogen
Progesterone
Gonadotropins
Prolactin
Gynaecology & Obstetrics
Endocrinology in Relation to Reproduction
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single
In the primary survey of a severely wounded patient 'cABCDE', 'c' stands for
Experience from war zones over the past 20 years has shown that exsanguinating external haemorrhage from massive aerial bleeding needs to be controlled even before the airway is managedIf identified, pressure should be applied, in an attempt to stem the flow of blood. When the tourniquet is applied, the time has to be ...
3
Care about surroundings
Call for help
Catastrophic haemorrhage
Cardiac status
Surgery
Trauma
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multi
Schwannoma arises most frequently from:
A schwannoma (also known as acoustic neuroma, acoustic neurinoma, or acoustic neurilemoma) is a benign, usually slow-growing tumor that develops from the vestibular nerves supplying the inner ear. The tumor comes from an overproduction of Schwann cells--the cells that normally wrap around nerve fibers like onion skin t...
1
Vestibular Nerve
Trigeminal nerve
Cochlear Nerve
Facial Nerve
ENT
null
25dbc164-0d6f-46ce-8646-2109dc883575
single
Which of the following toxic states is not associated with anemia?
Ans. is 'd' i.e., Listerosis * The toxic or chemical injury states associated with anemia include: Clostridial sepsis, Snake venom, Lead poisoningClassification of Anemia According to Underlying MechanismMechanismSpecific ExamplesBlood Loss Acute blood lossChronic blood lossTraumaGastrointestinal tract lesions, gynecol...
4
Clostridial sepsis
Snake venom
Lead poisoning
Listerosis
Medicine
Blood
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single
Enzyme deficiency in glycogen storage disease type 5 is:
D Harper, 26,h ed, p. 152, Table (18.2) & 25th ed, p. 206, Table (20.2)
4
Glucose 6 phosphatase
Acid maltase
De branching enzyme
Myophpsphorylase deficiency
Biochemistry
Carbohydrates
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single
The following are recognised signs any symptoms of raised intracranial tension in a 9 month old infant, except –
null
3
Bulging fontanel
Diplopia
Papilloedema
Increase in head size
Pediatrics
null
595c6fc4-87a1-49f1-b613-27685a796bde
multi
Which of the following is the root value of achilles tendon reflex?
Achilles tendon reflex:Also known as ankle jerk.Root value: S1,S2Plantar flexion of the ankle joint on tapping the Achilles tendon. Must know:Deep tendon reflexes include reflex responses of the biceps, triceps, brachioradialis, patellar and Achilles tendons. Ref: Clinical Anatomy By Regions By Richard S. Snell, 2011, ...
3
L1, L2
L3, L4
S1, S2
S3, S4
Anatomy
null
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single
Commonest trophozite infection by sexual intercourse -
Trichomoniasis has an estimated annual incidence of 173 million cases(Ref.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE 21st Edition page no.304)
2
Entamoeba histolytica
Trichomonas vaginalis
Trepanoma palidium
Giabrdia intestinales
Social & Preventive Medicine
Communicable diseases
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single
Maternal moality is maximum in which period -
Park's textbook of preventive and social medicine 23rd edition. *Maternal deaths mostly occur from 3rd trimester to 1st week after bih.
2
Antepaum
Peripaum
Postpaum
None
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics
d7bb7459-1bbc-4390-9a75-da5cd7e2e17a
multi
EAC rosette formation is the propey of one of the following type of immune cells ?
Ans. is 'a'
1
T-cells
B-cells
Macrophages
All of the above
Microbiology
null
823f4d8c-505f-410a-b5c3-25a2201e8012
multi
Mid tracheostomy is done at which of the following level?
Ref: Diseases of the Ear Nose and Throat by PL Dhingra 5th edn .2010 page page 337 Explanation:TracheostomyTracheostomy is making an opening in the anterior wall of trachea and converting it into a stoma on the skin surfaceIndications areRespiratory obstructionSuction of retained secretionsRespiratory insufficiencyType...
4
3-4 rings of tracheal cartilage
5-6 rings
1-2 rings
2-3 rings
ENT
Ear
473caf63-7b3b-48f7-8ad2-9cd943179973
single
Which of the following represents the indication for In-situ DNA nick end labeling technique?
It is an in-situ method for detecting areas of DNA which are nicked during apoptosis.In-situ methods for labeling apoptotic cells are used to demonstrate the DNA fragments produced by endonucleolytic cleavage directly within tissue sections. The in-situ methods makes use of enzymes that label 3'-OH ends that results fr...
1
To detect fraction of cells in apoptotic pathways
To detect fraction of cells in S phase
To detect p53 gene product
To detect bcr/abl gene
Pathology
null
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single
The need for vitamin B12 and folic acid inthe formation of red blood cells is related primarily of their effects on:
Within 6-9 hours of treatment with vitamin B12 formation of nuclear DNA component promotes normoblastic reaction of the bone marrow. Folic acid also promotes the formation of nucleic acids.
3
Synthesis and release of erythropoietin from the kidney
Absorption of iron from the gut
DNA synthesis in bone marrow
Hemoglobin formation in the red blood cell
Unknown
null
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single
A 3-year-old child is admitted to the emergency department with a particularly severe attack of asthma. Which of the following is the most important factor in increasing the intrathoracic capacity in inspiration?
Contraction of the diaphragm (descent) pulls the dome inferiorly, increasing the vertical dimension of the thorax. This is the most important factor in inspiration for increasing the internal pulmonary volume and concomitantly decreasing intrathoracic pressure. The contraction of intercostal muscles is usually involved...
4
"Pump handle movement" of the ribs-thereby increasing anterior-posterior dimensions of the thorax
"Bucket handle movement" of the ribs-increasing the transverse diameter of the thorax
Straightening of the forward curvature of the thoracic spine, thereby increasing the vertical dimensions of the thoracic cavity
Descent of the diaphragm, with protrusion of the abdominal wall, thereby increasing vertical dimensions of the thoracic cavity
Anatomy
Thorax
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multi
Harish 45 years old male admitted in hospital, says that nurse who is treating him is not actually nurse, his wife has replaced her and trying to killed him. Diagnosis.
Fregoli syndrome : Patient believes that family member has come in disguise of stranger.
2
Capgrass syndrome
Fregoli syndrome
Cotard syndrome
Alport syndrome
Psychiatry
null
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multi
A 40 year old married male thinks that he is multitalented and is always overconfident. He never listens to his family or friends. Infact whenever anyone gives him any advice, he thinks that they have some motive against him. He is always suspicious of his wife.All these are feature of?
Ans. C. Paranoid personality disorderParanoid personality disorder: It is characterized by generalized mistrust and suspiciousness about the motives and actions of others and a tendency to interpret them as malevolent. The patient believes that:Others are exploiting or deceiving the person.Friends are untrustwohy and n...
3
Borderline personality disorder
Schizoid personality disorder
Paranoid personality disorder
Histrionic personality disorder
Psychiatry
null
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multi
Wilm's Tumour is associated with all. except ?
Ans. is d i.e., Polycystic kidney disease
4
Hemihyperophy
Beckwith syndrome
Aniridia
Polycystic kidney
Pediatrics
null
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multi
Function of hepatic stellate cells are
The hepatic cells are of mesenchymal origin , found in space of Dessie. The stellate cells play a role in the storage and metabolism of vitamin A and are transform into collagen producing myofibroblast when there is inflammation and Fibrosis of liver. Refer 9/e p436
1
Vitamin A storage
Formation of sinusoids
Increase blood perfusion
Phagocytosis
Anatomy
G.I.T
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A 16-year-old girl presents with a painfully enlarged lymph node in her right axilla and low grade fever. Peripheral blood counts are within normal limits. The lymph node is biopsied, and numerous granulomas filled with neutrophils and necrotic debris are observed. Which of the following organisms could produce this di...
Baonella henselae is the infective agent of cat scratch disease, which generally presents as regional lymphadenopathy with or without low fevers and headaches. Baonella is a gram-variable pleomorphic rickettsial organism that is introduced to the skin in a cat bite or scratch. It produces a self-limited granulomatous r...
1
Baonella henselae
Borrelia burgdorferi
Chlamydia psittaci
Coxiella burnetii
Microbiology
null
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single
Calculate the filtration,if GFR = 125 ml / min and renal plasma = 625 ml / min
null
2
5%
20%
50%
10%
Physiology
null
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single
Characteristics of SIRS includes the following except -
null
2
Leukocytosis
Thrombocytopenia
Infectious or noninfectious cause
Oral temperature > 38°C
Medicine
null
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multi
Which of the following condition increase chance of hyponatremia in patient treated with antidepressant:
Ans. (A) Old ageCases of SSRl-associated hyponatremia & the syndrome of inappropriate antidiuretic hormone have been seen in some patients, especially those who are older or treated with diuretics.
1
Old age
Low weight
Cold climate
Obesity
Psychiatry
null
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Renal GFR is estimated by
C i.e. Tc99 DTPA DTPA is freely filtered at globerulus with no tubular reabsorption or excretion. Thus its excretion rate measures GFRQ. DTPA Scan is useful for evaluation of perfusion and function of each kidneyQ. It is also indicated in Urinary tract obstructionQ, Renovascular cause of hypeensionQ and Renal transplan...
3
TC99 DMCA
TC99DMSA
Tc99 DTPA
All
Radiology
null
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multi
Infraclavicular lesion of tuberculosis is known as -
Assman focus: Infraclavicular lesion of tuberculosis. Healed calcified caseous nodule of tuberculosis at the apex of the lung. Rich focus: Tuberculosis granuloma occurring on the coex of the brain that ruptures into the subarachnoid space. Simmons focus: Healed foci of TB in the liver Weiga focus: Healed foci of TB in ...
3
Ghon 'S focus
Puhl's focus
Assman's focus
none
Pathology
dermatology and infectious disease
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multi
Veebral rotation in scoliosis is checked in-
*The forward bending test is very sensitive in demonstrating the veebral rotation that takes place in a structural scoliotic curve. *Quantification of the rotation is done by measuring the rib hump by use of inclinometer or scoliometer. Ref: Oski's Paediatrics, Principles and practice p.2488
1
Forward bending
Backward bending
Sideways
Without bending
Anatomy
Spinal injuries
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A 9 months old child is brought to you in the emergency with complaints of cough and coryza since last 2 days. Since last 1 day child is having noisy breathing which increases on crying. On examination you find a stridor which the mother was explaining as noisy breathing. What is your diagnosis?
Ans. A. CroupCroup is the most common etiology for hoarseness, cough, and onset of acute stridor in febrile children. Symptoms of coryza may be absent, mild, or marked. The vast majority of children with croup recover without consequences or sequelae.Croup manifests as hoarseness, a seal-like barking cough, inspiratory...
1
Croup
Bronchiolitis
Asthma
Laryngomalacia
Pediatrics
Respiratory System
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single
The major contribution to the semen from:
Semen which is ejaculated during male sexual act is composed of fluid and sperm. vasdeferens-10% seminal vesicles-60%-mucoid consistency prostate gland-30%-milky so the bulk of semen is seminal vesicle fluid
2
Testes
Seminal vesicles
Prostate
Bulbourethral and urethral glands
Gynaecology & Obstetrics
null
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single
Uric acid is formed by ?
Ans. is 'c' i.e., Catabolism of purines
3
Catabolism of proteins
Catabolism of ketones
Catabolism of purines
Catabolism fo pyrimidines
Biochemistry
null
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single
The weight of the upper limb is transmitted to the axial skeleton by ?
The weight of the upper limb is transmitted to the medial two-third of the clavicle and thence to the axial skeleton through the coraco-clavicula ligament.
1
Coracoclavicular ligament
Coracoacromial ligament
Costroclavicular ligament
Coracohumeral ligament
Anatomy
null
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single
Secondary caries is least likely seen with:
null
1
Silicate cement
Zinc phosphate
Polycarboxylate
GIC
Dental
null
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single
One of your patients is diagnosed with retinoblastoma. He has a single tumor in one eye. The patient is worried whether his children would suffer from the same condition. What test could be used to determine whether it is a heritable or sporadic tumor?
Foy percent of retinoblastomas are heritable; the child inherits one mutant allele through the germline and a somatic mutation in the other allele occurs, resulting in the loss of function of that gene. This leads to tumor development, often with multiple tumors in both eyes. Penetrance, however, is not complete, since...
4
DNA footprinting
Fluorescence-activated cell soing (FACS)
Nohern blotting
PCR
Biochemistry
null
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single
Cytochrome C of the bacteria has 50% identity of amino acid sequence with that of a human. Which of the following is the most conserved parameter in these two proteins
Pseudomonas (bacterial) cytochrome C differs from eukaryotic (human) cytochrome in the total number of amino acid residues, in composition and in the order of residues in the large segment of amino acid sequence' Comparison of primary protein structure with the predicted tertiary structure revealed that functionally cr...
2
Quarternary structure
Tertiary structure
Amino acid sequence
Loop and turn segments
Biochemistry
null
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single
To test hepatic function to assess bleeding disorder clinical test done is:
PTT
2
CT, BT
PTT
Factor 8
None of the above
Pathology
null
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multi
In Peutz-Jeghers syndrome, polyps are seen in
Answer is C (Small bowel) Polyps may be seen throughout the gastro intestinal tract but most commonly in the small intestine. Peutz Jegher's syndrome: It is an autosomal dominant condition characterized by: Hamaomatous polyps throughout the gastrointestinal tract, most notably in .small intestineQ Mucocutaneous pigment...
3
Colon
Rectum
Small bowel
Stomach
Medicine
null
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multi
Which statement regarding the renal involvement associated with SLE is true?
Renal disease is clinically evident in about half of persons with SLE. However, nearly all persons with SLE have some evidence of renal disease on renal biopsy. Renal disease associated with SLE includes both glomerulonephritis and interstitial nephritis. Glomerular disease has been classified into membranous nephritis...
3
Clinically apparent renal disease occurs in 90% of affected persons
Interstitial nephritis is a rare finding on renal biopsy
Renal biopsy is not initially necessary in patients with deteriorating renal function and active urine sediment
Renal disease is uncommon in patients with higher anti-double stranded DNA antibodies
Unknown
null
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multi
Kenny Packs were used in the treatment of -
null
1
Poliomyelitis
Muscular dystrophy
Polyneuropathies
Nerve Injury
Medicine
null
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single
A 74-year-old woman presents with acute chest pain and shoness of breath. Cardiac catheterization demonstrates occlusion of the left anterior descending coronary aery. Laboratory studies and ECG are consistent with acute myocardial infarction. Which of the following is the most likely pathological finding in the affect...
Pathologic findings in congestive hea failure include:- Change Time Microscopic signs of coagulative necrosis 24 hours after the onset of vascular occlusion PMNL and marophages 3-5 days from the time of injury Capillary rich granulation tissue 7 days or end of first week Collagen rich scar tisssue(necrotic myocardium i...
2
Capillary-rich granulation tissue
Collagen-rich scar tissue
Granulomatous inflammation
Neutrophils and necrotic debris
Pathology
Wound Healing
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single
Which of the following Scaphoid fracture is most prone to develop Avanscular necrosis?
A i.e. Fracture of waist of Scaphoid
1
Fracture of waist of scaphoid
Fracture of tubercle
Fracture of distal pole
All of the above
Surgery
null
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multi
First line of treatment for keloid is
First line of management for keloid is intra keloidal injection of Triam cinolone acetate.
1
Intralesional injection of steroid
Local steroid
Wide excision
Radiotherapy
Surgery
null
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single
A 9 yr old girl has difficulty in combing hairs and climbing upstairs since 6 months. She has Gower's sign positive and maculopapular rash over metacarphalangeal joints. What should be the next appropriate investigation to be done?
The mitochondrial creatine kinase (CKm) is present in the mitochondrial intermembrane space, where it regenerates phosphocreatine (PCr) from mitochondrially generated ATP and creatine (Cr) impoed from the cytosol. Apa from the two mitochondrial CK isoenzyme forms, that is, ubiquitous mtCK (present in non-muscle tissues...
3
ESR
RA factor
Creatine kinase
Electromyography
Medicine
C.N.S
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During delivery there is a perineal tear involving the anal sphincter but anal mucosa is not involved. Which is the degree of tear?
Ans. (c) IIIRef. DC Dutta 7th ed./ 422-23PERINEAL TEARS1st degreeIs a laceration of the vaginal mucosa and the perineal skin but not the underlying fascia and muscle.2nd degreeInvolves the vaginal mucosaperineal skinand the fascia and muscles of the perineal body.3rd degreeInvolves the vaginal mucosaskin and perineal b...
3
I
II
III
IV
Gynaecology & Obstetrics
Injury to the Birth Canal
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single
Ranula is a -
null
1
Mucous cyst
Tumor
Submandibular gland swelling
Swelling on dorsum of tongue
ENT
null
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single
Most sensitive investigation for diagnosis of Meckel's diverticulum is?
Ans DImaging wise Meckel diverticulum appears like normal bowel, however Meckel's bleeds because it has ectopic gastric mucosa - secretes acid - damages the mucosa. Most common presentation of Meckel's: GI bleedingQ with abdominal pain. Tc99m - pertechnate scan is most sensitive for diagnosisQ
4
USG
CT Scan
Barium enema
99m-Tc pertechnetate scan
Radiology
G.I.T.
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Which is a Chemoattractant -
Ans-C5a* Major opsonins: C3b, IgG, mannose-binding lecithin (MBL), fibronectin, fibrinogen, and CRP.* Membrane attack complex: MAC has a subunit composition of C5b, C6, C7fC8, and polymeric C9* Anaphylatoxin: Both C3a and C5a anaphylatoxin activity.
1
C5a
Cl
C3
C2
Unknown
null
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single
If a patient is absolutely allergic to LA, the specific drug used in place of it is:
If the patient is allergic: To ester local anesthetics, try an amide local anesthetic. To amide local anesthetics, try an ester local anesthetic. To methylparaben or is allergic to both amide and ester local anesthetics, try a MPF product. To antioxidants or sulfite compounds, review the product ingredients. Some  dr...
3
Chlorpheniramine maleate
Benzalkonium chloride
Diphenhydramine hydrochloride
Ketamine hydrochloride
Surgery
null
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multi
Cherry red postmortem staining is seen in
Ans. is 'b' i.e., Carbon monoxide * Color of post-mortem staining in various poisoning:POISONCOLORCarbon mono-oxide and hypothermiaCherry redHCN, burnsBright redNitrites, potassium chlorate, potassium bicarbonateNitrobenzene, acetanilide, bromates, aniline (causing methaemoglobinuria)Chocolate or Copper brownPhosphorou...
2
Cyanide
Carbon monoxide
Nitrites
Phosphorus
Forensic Medicine
Toxicology
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single
Interocclusal distance is required because
The interocclusal distance is a necessity, when the mandible is at rest, as it permits supporting hard and soft tissues to rest.
2
It is essential in complete denture construction
It permits supporting tissues to rest
It helps in mounting casts
None of the above
Dental
null
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multi
TNF is secreted by activated:
Ans: a (Macrophages) Ref: Robbins,7th ed, p. 71; Ananthanarayan, 7th ed, p. 144; Table 16-2TNF and IL1 are the main mediators of inflammation. They are produced mainly by the activated macrophages.Cytokines and their main sourcesILl, IL 8- MacrophagesIL 2, 3, 9, 10, 12, 13- T cellsIL 4, 5, 6- Helper cellsIL 7, 11- Stro...
1
Macrophages
Neutrophils
Lymphocytes
Eosinophils
Pathology
Cellular Pathology
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single
Cock&;s peculiar tumor is
.cocks peculiar tumour is actually a complication of sebaceous cyst when sebaceous cyst ulcerates excessive granulation tissue forms resembling fungating epithelioma and this iscalled cock&;s peculiar tumour
3
Basal cell CA
Squamous cell CA
Ulcerated sebaceous cyst
Cylindroma
Surgery
General surgery
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Which of the following endocrinological condition may be associated with hydatiform mole :
Hypehyroidism
2
Hypothyroidism
Hypehyroidism
Diabetes
Hyperprolactinemia
Gynaecology & Obstetrics
null
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Which of the following is the most common tumor of the salivary gland?
Pleomorphic adenoma is the most common salivary gland tumor in both children and adults. Women are more commonly affected, and the mean age at presentation 4th to 6th decade. Patients present with painless, slow growing mass. On examination it is a solitary, well defined, firm and mobile mass. Within the parotid gland ...
4
Mucoepidermoid tumor
Wahin's tumor
Acinic cell tumor
Pleomorphic adenoma
Surgery
null
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Parvovirus infection which of the following is true
Ref. Robbins Pathology. 9th edition. Page. 460   Parvovirus B19 directly infects eiythroid progenitors through the P antigen on erythroblast surface. Individuals who lack P antigen are resistant to parvovirus infection. Few giant proerythroblasts (GFE) with basophilic cytoplasm 'dogear1 like cytoplasmic projections, s...
1
Erythroid progenitors are affected
Myeloid precursors are affected
People with P antigen is resistant to infection
Majority are chronic infections
Unknown
null
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All of the following cause hypeension except:
L-dopa a. NSAID Cause retention of sodium and water causing oedema and also decreases the effects of antihypeensive drugs. Hypeension is more common in coxib users than NSAID. c. Cyclosporine May cause hypeension in 50% of renal transplants and in almost all cardiac transplants. d. L-Dopa Peripheral decarboxylation of ...
4
NSAID
Erythropoietin
Cyclosporine
L-dopa
Surgery
null
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multi
Most commonly used cholinesterase regenerator at NM junction is -
Ans. is 'a' i.e., Pralidoxime o Pralidoxime is most commonly used cholinesterase reactivater.OXIMESo Oximes 1 Pralidoxime 2-PAM, obidoxime and diacetyl-monoxime (DAM)J are used in organophosphatepoisoning.o Oximes acts by reactivating cholinesterase enzyme.o Mechanism of actionIn organophosphate poisoning esteratic sit...
1
Pralidoxime
Obidxime
Diacetyl monoxime
Edrophonium
Pharmacology
Cholinergic System
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The bacterial cell wall has all of the following properties except:
null
3
It consists of a mixed polymer called peptidoglycon
It is the structure principally responsible for the reaction of gram staining
It is a unique flexible plastic structure
It contains D-isomers of amino acids
Microbiology
null
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multi
Scottish Dog Terrier Appearance on X-ray is seen in:
Scottish Dog Terrier sign is Normal appearance of lumbar spine on posterior oblique X ray view Scottish Dog Collar sign is seen in Spondylolysis Beheaded Scottish Dog Sign is seen in Spondylolisthesis Winking Owl Sign is seen with Veebral Metastasis
3
Spondylolysis
Spondylolisthesis
Normal Lumbar spine on Posterior oblique view
Veebral metastasis
Radiology
Musculoskeletal Radiology
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Moures sign is seen in -
Ans. is 'a' i.e.,Carcinoma"In normal persons, a click is felt when larynx is moved from side to side over vertebral column, this is called laryngeal click (post cricoid crepitus) It is absent in post cricoid carcinoma -- Moures sign
1
Carcinoma
Appendicitis
Varicose vein
Pancreatitis
Surgery
Miscellaneous (Neoplasia)
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Not a feature of hepato-renal syndrome:
Hepato-renal syndrome is a form of functional renal failure without renal pathology. Diagnosis is made in the presence of a large amount of ascites in patients who have a step-wise progressive increase in creatinine. Type 1 HRS is characterized by a progressive impairment in renal function and a significant reduction i...
1
Normal GFR
Normal urinary sediments
Low Na+ in urine
Normal renal biopsy
Medicine
Cirrhosis
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Lysosomal accumulation of sphingomyeline is seen in
null
2
Farber’s disease
Niemann-Pick disease
Tay Sach’s disease
Krabbe’s disease
Biochemistry
null
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single
All the following are posterior relations of IIIrd pa of Axillary aery except
Pectoralis minor divides the axillary aery into three pasRelations of Third PaAnterior1 Skin2 Superficial fascia3 Deep fascia4 In the upper pa, there are the pectoralis major and the medial root of the median nerve Posterior1 Radial nerve 2 Axillary nerve in the upper Pa3 Subscapularis in the upper Pa4 Tendons of the l...
3
Radial Nerve
Axillary Nerve
Ulnar Nerve
Teres Major and Subscapularis
Anatomy
Upper limb
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Variation of eruption of secondary dentition can be:
null
3
4-5 months.
6-7 months.
12-18 month.
Variations in eruption of secondary dentition is less frequent.
Dental
null
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If annual growth rate of a population is 1.5-2%, what number ofyears will be required to double the population?
Ans. is 'b' i.e. 47-35 years
2
70-47 years
47-35 years
35-28 years
28-23
Social & Preventive Medicine
null
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single
Root value of ankle jerk
The ankle jerk reflex, also known as the Achilles reflex, occurs when the Achilles tendon is tapped while the foot is dorsiflexed. This reflex is mediated by the S1 spinal segment of the spinal cord. Ref: guyton and hall textbook of medical physiology 12 edition page number: 774,775,776
3
L3 L4
L4 L5
S1 S2
S3 S4
Physiology
Nervous system
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A 32-year-old woman goes to an emergency depament because she has developed severe, watery diarrhea. About 36 hours later, she developed vomiting and an abrupt, painless, watery diarrhea. The volume of diarrhea has been copious, and she has subsequently developed intense thirst, oliguria, muscle cramps, and weakness. A...
The features noted are those of Vibrio cholerae, the causative organism of the severe diarrheal disease, cholera. The diarrhea is the result of the action of the cholera enterotoxin, which acts by ADP-ribosylating adenylate cyclase, leading to increased cyclic AMP with secondary increased efflux of Cl- and H2O. World-w...
4
Pseudomonas
Salmonella
Shigella
Vibrio cholerae
Microbiology
null
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single
Diameter of graafian follicle at the time of ovulation is -
Ans. C. 20mmOvulation is aprocessby which a secondary oocyte is released from the ovaryfollowingrupture of a mature Graafian follicle and becomes available for conception.There is a pre - ovulatory enlargement in the Graafian follicle and it measures about 20 mm at the time of ovulation.
3
10mm
15mm
20mm
25mm
Gynaecology & Obstetrics
null
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Reduction in central_____ plays a vital role in suicidal behavior.
Ans. c (Serotonin) (Ref. Harrison's medicine 17th ed., 2717; Kaplan & Sadock's Synopsis of Psychiatry, 10th ed., p. 901)Biological Factors in Suicide# Diminished central serotonin plays a role in suicidal behavior.# Low concentrations of CSF 5-HIAA also predicts future suicidal behavior.ETIOLOGY AND PATHOPHYSIOLOGY OF ...
3
Dopamine
Acetylcholine
Serotonin
Epinephrine
Psychiatry
Mood Disorders
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Type of collagen found in basement membrane -
Ans. is 'd' i.e., IV o Type IV collagen with laminin are the major constituent of basement membrane.Type of collagenDistributionType ISkin, tendon, bone, corneaType IIArticular cartilage, intervertebral disc. Vitreous humorType IIIFetal skin, cardiovascular systam, lung, reticular fiberType IVBasement membraneType VPla...
4
I
II
III
IV
Physiology
Cell Physiology and Intercellular Connections
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single
According to the 2010 WHO criteria the characteristics of normal semen analysis are:
Ans. A. Volume 1.5ml, count 15million/ml, morphology 4%, progressive motility 32%a. Semen volume: 1.5mL or moreb. pH:7.2 or morec. Count: 15million/mL or mored. Motility (within 1 hour of collection) Total motility (progressive + non progressive): 40% or moree. Progressive motility: 32% or moref. Vitality (live spermat...
1
Volume 1.5ml, count 15 million/ml, morphology 4%, progressive motility 32%
Volume 2.0ml, count 20 million/ml, morphology 4%, progressive motility 32%
Volume 1.5ml, count 20 million/ml, morphology 4%, progressive motility 32%
Volume 2.0ml, count 15 million/ml, morphology 4%, progressive motility 32%
Gynaecology & Obstetrics
Physiological changes during Pregnancy
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Investigation of choice in peptic ulcer perforation is -
null
2
USG
X-Ray abdomen
Paracentesis
CT scan
Surgery
null
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single
Memory T cells can be identified by using the following marker:
CD 45 is called as Leukocyte common antigen (LCA) Location of cell Molecular marker All leucocytes CD45 and CD45RB Medullary thymocytes ('Naive' T- cells) CD45 RA and CD45RC Coical thymocytes (Memory T-cells) CD45RO
4
CD45RA
CD45RB
CD45RC
CD45RO
Pathology
Immunology
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Treatment of choice in case of chronic ulcerative colitis is:
Indications of Surgery in Ulcerative Colitis 1) Intractability2) Dysplasia or Carcinoma3) Massive Colonic bleeding4) Toxic Megacolon Surgical options in Ulcerative colitis1) TPC + IPAA - Definitive Rx2) TPC + Ileostomy3) TPC + Continent ileal reservoir (Kock pouch)4) TAC + End ileostomy TPC + IPAA- It is the Definitive...
3
Colectomy with ileostomy
Colectomy + manual proctectomy + ileoanal pouch anastomosis
Proctocolectomy with ileoanal pouch anastomosis
Ileorectal anastomosis
Surgery
Inflammatory bowel disease
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T1 weighted MRI of midsagittal section of brain is given. Which among the marked structures contains two lateral foramina of Luschka ?"
Option D : Correct answer i.e. the fouh ventricle contains the two lateral foramina (of Luschka), which drain into the two cerebellopontine angle cisterns. Option A : lateral ventricle Option B : third ventricle with fornix and choroid plexus at the roof Option C : quadrigeminal cistern with great cerebral vein (of Gal...
4
A
B
C
D
Anatomy
Neuroanatomy 1
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single
A 5-year old child presented with fever, fatigue, abdominal pain and vomiting. On fuher history evaluation, he had a habit of eating di. Investigations shows visceral larva migrans. Communication with the following agent must have caused this infection in this child:
The agent for Toxocariasis (visceral larva migrans) is the cosmopolitan intestinal ascarid of dogs and cats, Toxocara canis or Toxocara cati. The eggs passed by infected animals contaminate parks and other areas that young children frequent. Children with pica are at increased risk. Ingested eggs hatch and penetrate th...
2
Pig
Dogs
Monkeys
Cows
Microbiology
null
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single
Low LAP score may be seen in the following EXCEPT: September 2012
Ans. D i.e. Polycythemia vera Diagnostic criteria for polycythemia vera Accurate diagnosis of PV is critical because its treatment may require the use of drugs with the potential to cause leukemia. The patient is considered to have PV if all three major criteria are met; or if the first two major criteria and any two m...
4
CML
Paroxysmal nocturnal hemoglobinuria
Autoimmune hemolytic anemia
Polycythemia vera
Medicine
null
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multi
Unilateral watery discharge from the eye of a new born, with no edema or chemosis is due to:
D i.e. Chemical conjunctivitis Here the neonate has Ophthalmia Neonatorum. Early presentation of discharge may be due to Gonococcus Q or Chemical Conjunctivitis Q, but Gonococcus is almost always B/L so the answer here is Chemical Conjunctivitis. In the past, if a maternal infection was suspected a drop of silver nitra...
4
Chamydia
Gonoccocos
Sticky eye
Chemical conjunctivitis
Ophthalmology
null
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single
The most reliable investigation in amyloid disease is -
Ans. is 'a' i.e., Rectal biopsy
1
Rectal biopsy
Immunoglobulin assay
Ultrasound
Urine examination
Pathology
null
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single
Primordial germ cell is derived from:
A i.e. EctodermPrimordial germ cell develops from epiblast (primitive or primary or embryonic ectoderm)Q at the caudal end of primitive streak in the caudal end of embryo. In the 3rd week, primordial germ cells migrate to a mass of extra embryonic mesoderm and then into the endoderm of yolk sac wall.
1
Ectoderm
Mesoderm
Endoderm
Mesodermal sinus
Anatomy
null
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single
Wagner's granulomatosis does not affect?
Liver REF: Harrison's Principles of Internal Medicine 17th ed chapter 319 MANIFESTATION OF WAGNER'S GRANULOMATOSIS: Kidney: Glomerulonephritis Ear/nose/throat: Sinusitis Nasal disease Otitis media Hearing loss Subglottic stenosis Ear pain Oral lesions Lung: Pulmonary infiltrates Pulmonary nodules Hemoptysis Pleuritis E...
1
Liver
Lung
Kidney
Eye
Surgery
null
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single
A G1+O attends the antenatal clinic for the booking visit at 12 weeks. Her blood group is B Rhesus negative.What is the next step in the management?
Ans. is b, i.e. Determine the husbands blood groupWhen a rhesus negative primipara attends the antenatal clinic, the first step is to determine her husband's blood group. If the husband is Rhesus negative no further investigations are necessary, as all babies will be Rhesus negative.
2
Determine the fetal blood group
Determine the husband's blood group
Perform an ultrasound scan
Perform Rhesus antibody titer
Gynaecology & Obstetrics
Pregnancy in Rh-negative Women
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Dialysis disequalibrium occurs due to -
Ans. is 'a' i.e., Cerebral edema o Two ty pes of neurological disturbance are unique to patients on chronic dialysis.A) Dialysis dementiaQB) Dialysis disequilibriumQDialysis dementia -o It may occur in patients who have heen on dialysis for many years0 and is characterized by dyspraxia, myoclonus, dementia and eventual...
1
Cerebral edema
Hypertension
Alumunium toxicity
A amyloid deposition
Medicine
Dialysis
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single
A young girl presents with repeated episodes of throbbing occipital headache associated with ataxia and vertigo. The family history is positive for similar headaches in her mother. Most likely diagnosis is -
null
2
Vestibular Neuronitis
Basilar migraine
Cluster headache
Tension headache
Medicine
null
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single
Which of the following strategy has been recommended to reduce the heredity risk for ovarian cancer in women with BRCA -1 and BRCA - 2 mutations :
Ans. is d i.e. Prophylactic oophorectomy BRCA-1 and BRCA-2 are tumour suppressor genes. BRCA-1 is located on chromosome 17 and BRCA-2 on chromosome 13. Individuals who inherit mutations of BRCA-1 and BRCA-2 are highly susceptible for the development of hereditary breast or ovarian cancer. The mutations are inherited as...
4
Use of oral contraceptive pills
Screening with transvaginal ultrasound
Screening with CA - 125
Prophylactic oophorectomy
Gynaecology & Obstetrics
null
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single
Indication for stopping rifampicin ?
Ans. is'c'i.e., ThrombocytopenialRef: ATT drug guide p. 7391Among the given options, hepatitis and thrombocytopenia are adverse effects of rifampicin."If thrombocytopenia purpura or anaemia occurs, rifampin should be stopped and should never be restaed".Rifampicin can be restaed under close observation and supervision,...
3
Hepatitis
Visual loss
Thrombocytopenia
Peripheral neuropathy
Pharmacology
null
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single
Flower 'Vase' pattern of the pelvis in an intravenous urogram is seen in -
null
3
Polycystic kidney
Renal carcinoma
Horse shoe kidney
Ectopic kidney
Surgery
null
a5b9249f-bf74-4b92-bb77-2dc5b1ccc17c
single
Of the light produced by quartz — tungsten -halogen, only a small percentage is suitable for curing composite resin material and most is converted into heat. How much percentage of this light is useful for curing?
null
1
0.50%
5%
10%
50%
Dental
null
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multi
Inferior longitudinal muscle:
null
2
Shortens the tongue mad makes the dorsum concave.
Shortens the tongue and makes the dorsum convex.
Narrow and elongates the tongue.
None.
Anatomy
null
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When sebaceous cyst of the scalp is ulcerated, excessive granulation tissue forms fungating epithelioma is known as:
null
1
Cock's peculiar tumour.
Sebaceous horn.
Sequestration dermoid.
Terstomatous dermoid.
Surgery
null
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single
Uro-rectal septum separates the cloaca into?
D i.e. Rectum and urogenital sinus
4
Rectum and bladder
Anus and urethra
Allantois and blader
Rectum and urogenital sinus
Anatomy
null
1230825b-8657-445d-80c6-98c3bf608a80
multi
Regarding cystic disease of breast which one is true:
Ans. is 'd' ie Aspiration is the t/t Cysts are considered foremost among all of the benign histological changes in the breast. They occur most commonly in the last decade of reproductive life due to a nonintegrated involution of stroma and epithelium. Remember, cysts are one of the many features seen in ANDI (Aberratio...
4
Common in 25 years of age
Excision is the treatment
may turn into malignant
Aspiration is the treatment
Surgery
Neck
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multi
Which of the following is the most common malignant germ cell tumor of ovary?
Ans. is 'b' i.e., Dysgerminoma Dvsgerminomao It is the most common malignant germ cell tumor of ovary,o It affects young women and is usually unilateral.o Bilateral tumors are seen in 15 - 20% of the cases.o It is fleshy in consistency.o Histologically it shows presence of lymphocytic infiltration which is considered a...
2
Yolk sac tumor
Dysgerminoma
Polyembryoma
Choriocarcinoma
Gynaecology & Obstetrics
Pathology (Carcinoma Ovary)
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single
In the Rabies vaccine schedule of 0,3,7,14,30,90,0 means -
The vaccination schedule recommended consists of 6 doses on day 0,3,7,14,28 and a booster dose on day 90(Ref.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE 21st Edition page no.255)
2
Day of dog bite
Day of first injection
Day of symptom onset
Day of dog death
Social & Preventive Medicine
Communicable diseases
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