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Which of the following is not a second messenger
Ans. c. Guanylyl cyclase
3
c-AMP
IP3
Guanylyl cyclase
Diacylglycerol (DAG
Physiology
null
a1466554-d744-4c7b-8ee3-c67ad4002776
single
Artery of 2nIi pharyngeal arch is -
Ans. is 'b' i.e., Stapedial artery Pharyngeal ArchMuscular ContributionSkeletal ContributionsNerveArteryCorresponding Pouch Structures1st (mandibular arch)Muscles of mastication, Anterior belly of the digastric,Mylohyoid,Tensor tympani.Tensor veli palatiniMaxilla, mandible (only as a model for mandible not actual forma...
2
Maxillaiy artery
Stapedial artery
Subclavian artery
Commoncarotid artery
Anatomy
Pharyngeal Arches
5657beed-dfea-441f-b062-b75fc1de5be5
single
What is the probable diagnosis in a patient with a dilated pupil not responsive to 1% pilocarpine
Refer Goodman and Gilman 12e 1777 Looking at the option one by one diabetic third nerve palsy: third Nerve Palsy due to any reason will result in mydriasis( because oculomotor people milk supplies constrictor pupillae). As only one nerve is destroyed and but the receptors remain intact , so it will respond to 1% piloca...
4
Diabetic third nerve palsy
Ade's pupil
Uncal Herniation
Pharmacological block
Pharmacology
Autonomic nervous system
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single
Alcohol causes -
o Chronic Alcohol consumption is the most common cause of Toxic Dilated Cardiomyopathy. ‘Alcohol is the most common toxin implicated in chronic dilated cardiomyopathy.' - Harrison 18th/e p. 1961
1
Dilated cardiomyopathy
HOCM
Restrictive cardiomyopathy
None
Pathology
null
8e9028c1-4c45-4f8c-af6a-1ef61a385a81
multi
Colonic polyp with most malignant potential is -
Ans. is 'd' i .e., Sessile Adenomatous poly p o Adenomatous polyps have special clinical significance because only adenomatous polyps are clearly premalignant, and only a minority of these adenomatous lesions ever develop into a cancero Clinically, the probability of an adenomatous polyp becoming a cancer depends on th...
4
Juvenile polyp
Hyperplastic polyp
Pedunculated Adenomatous polyp
Sessile Adenomatous polyp
Surgery
Colon and Rectum - Polyps and Carcinoma
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single
Which is not true regarding Bernard soulier syndrome?
null
1
Ristocetin aggregation is normal
Aggregation with collagen and ADP is normal
Large platelets
Thrombocytopenia
Medicine
null
5b210f0f-0e6b-4466-94fc-211b8bb996a9
multi
Which of the following is essential for tumor metastasis?
Metastasis is a complex series of steps in which cancer cells leave the original tumor site and migrate to other pas of the body the bloodstream or the lymphatic system. One of the critical events required for metastasis is the growth of a new network of blood vessels, called tumor angiogenesis.
1
Angiogenesis
Tumorogenesis
Apoptosis
Inhibition of tyrosine kinase activity
Pathology
General Concepts
9efe2795-0071-4b09-a6f7-24f2d397c3d4
single
Which of the following glomerular disease is associated with Crescent formation?
The most common histological picture of Rapidly progressive glomerulonephritis is the presence of crescents in most of glomeruli. Crescents are formed by proliferation of parietal cells and by migration of monocytes and macrophages in the Bowman's space. The prognosis can be roughly related to the number of crescents. ...
2
Minimal change disease
Rapidly progressive glomerulonephritis
Focal and segmental glomerulosclerosis
Rapidly non progressive glomerulonephritis
Pathology
null
08d1ac58-a538-43ed-afd6-7965cfd6b103
single
Agglutination test is -
Weil- Felix reaction for the diagnosis of typhus fever. - The Agglutination reaction is when a paiculate antigen is mixed with its antibody in the presence of electrolytes at a suitable temperature and pH, the paicles are clumped or agglutinated. Reference : Anathanarayan & paniker's 9th edition, pg no: 108,109 <\p>
3
ABO incompatibility
VDRL
Weil-felix test
FTA-ABS
Microbiology
Immunology
4a365a2f-fd9f-421c-bce4-ffcda2196b0c
single
Which of the following vessels is involved in extradural haematoma?
Ans. a (Middle meningeal artery). (Ref: B & L, Surgery, 25th/ 303).Extradural haematoma (EDH)# It is a neurosurgical emergency. An EDH is nearly always associated with a skull fracture and is more common in young male patients. The skull fracture is asso- ciated with tearing of a meningeal artery and a haematoma accumu...
1
Middle meningeal artery
Venous sinuses
Bridging veins
Middle cerebral artery
Surgery
Nervous System
f96036bf-c381-4797-bf2e-68aebe5329d1
single
Man is intermediate host for -
option-1- Life Cycle of Plasmodium: Malaria is caused by Plasmodium species. Definitive host: Female Anopheles mosquitoes Intermediate host: Man. option- 2-Tuberculosis is caused by Mycobacterium tuberculosis and doesn't have secondary host. option-3- In Filariasis (W. bancrofti): man is definitive host. option-4- Borr...
1
Malaria
Tuberculosis
Filariasis
Relapsing fever
Microbiology
Parasitology Pa 1 (Protozoology)
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single
Drug of choice for bleeding oesophageal varices is?
Ans. is 'b' i.e., Octreotide Among the given options, only octeride is used (otherwise vasopressine analogue terlipressine is the DOC). Has been explained in previous sessions.
2
Ethanolamine oleate
Octreotide
Propanolol
Phytonadione
Pharmacology
null
662e8eea-1113-4590-a083-a6d028abfee1
single
Two or more oligoclonal bands in cerebrospinal fluid are most often positive in-
Oligoclonal bands (OCBs) are bands of immunoglobulins that are seen when a patient's blood serum, or cerebrospinal fluid (CSF) is analyzed. They are used in the diagnosis of various neurological and blood diseases, especially in multiple sclerosis. The blood serum can be gained from a clotted blood sample. Ref Davidson...
2
Acute bacterial meningitis
Multiple sclerosis
Subarachnoid harmorrhage
Polyneuropathy
Medicine
C.V.S
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single
Iodine deficiency control programme ?
Ans. is 'c' i.e., Foification of salt Iodized salt (salt foified with iodine) is most economical, convenient and effective means of mass prophylaxis in endemic area.
3
Health education
Water testing
Foification of salt
None
Social & Preventive Medicine
null
6adc35b5-1e0c-4d36-9d35-b66fe85eb9fc
multi
All of the following are sexually transmited, Except-
null
2
Candida albicans
Echinococcus
Molluscum contagiosum
Group B streptococcus
Microbiology
null
6e3fb46f-ca30-4715-b15f-255d75b51ae6
multi
All of the following methods are anti-larval measures, EXCEPT:
Malathion is used primarily for killing adult mosquitoes. It is not recommended as a larvicidal agent Fenthion, Chlorpyrifos and abate are preferred as larvicides. Water management such as intermittent irrigation constitutes a proven method of larval control. Paris green or copper acetoarsenite is a stomach poison and ...
4
Intermittent irrigation
Paris green
Gambusia affinis
Malathion
Social & Preventive Medicine
null
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multi
IPC 82 states that: child cannot be punished under what age -
Ans. is 'c' i.e., 7yrs o Section 82 I.P.C.: Criminal responsibility is any act which is done by a child under seven years of age is not an offence.Section of IPCRelated with82A child under the age of seven is incapable of committing an offence. This is so because action alobe does not amount to guilt unless if is accom...
3
5yrs
8yrs
7yrs
lOyrs
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
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Treatment of choice for generalized anxiety disorder is?
Ans is 'a' i.e. Benzodiazepines Treatment of generalized anxiety disorderA Benzodiazepines are the drug of choice. Drugs in this group are diazepam, Lorazepam, Alprazolam, Oxazepam, chlordiazepoxide.B. Other drugs used are buspirone; TCA (amptriptyline, imipramine, clomipramine, desipramine); SSRIs (Fluoxetine, Sertali...
1
Benzodiazepines
Neuroleptics
Beta blockers
Barbiturates
Psychiatry
Anxiety & Stress
74fc2f1d-6b36-435d-a477-59f4377e89ff
single
Which of the following agents may precipitate bronchospasm in patients with reactive airway disease?
Methohexital is an ultra-sho-acting barbiturate that provides sedation and amnesia for sho, invasive procedures. Barbiturate administration may precipitate bronchospasm in patients with moderate to severe reactive airway disease, thus limiting its use in those patients. There is some evidence that ketamine may have a m...
3
Midazolam
Etomidate
Methohexital
Propofol
Surgery
null
93914da7-d12b-42e7-a6d3-1843db7333b4
single
Vegetations below the AV valves are present in -
null
1
Libman-Sacks endocarditis
Chronic rheumatic carditis
Acute rheumatic carditis
Non thrombotic endocarditis
Pathology
null
e14c15ab-2ef2-4ad3-beac-80a63ac04d6d
single
"Chemical pregnancy" means :
Positive beta HCG and absent gestational sac
3
Negative beta HCG and absent gestational sac
Positive beta HCG and present gestational sac
Positive beta HCG and absent gestational sac
Negative beta HCG and created sac margin
Gynaecology & Obstetrics
null
7a5a29eb-3cba-4e5f-b5a2-6d6f37699bc8
single
Which of the following Biomedical wastes cannot be disposed off in yellow bags?
Yellow color bags are used for disposal of: BMW Cat 1: Human anatomical wastes BMW Cat 2: Animal wastes BMW Cat 3: Microbiological and biotechnology waste BMW Cat 6: Soiled waste Container/bags are not required for disposal of BMW Cat 8: Liquid waste BMW Cat 10: Chemical waste BMW Cat 3: (if disinfected locally): Micro...
1
Reactive chemical wastes
Radiographic wastes
PVC
Human anatomical wastes
Social & Preventive Medicine
Hospital waste and disaster management, Occupational health
870038bf-a1ee-4634-ad67-18ff128d3284
single
Which of the following bacteria contains mycolic acid in the cell wall
Mycobacterium are slender rods that sometimes show branching, filamentous forms resembling fungal mycelium. In liquid cultures, they form a mould like a pellicle. they do not stain readily, but once stained, resist decolourisation with dilute mineral acids, due to the presence of mycolic acid in their cell wall. They a...
3
Escherichia
Mycoplasma
Mycobacteria
Staphylococcus
Microbiology
Bacteriology
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multi
Child criteria doesnt include
Variables in Child-Turcotte-Pugh scoring system Serum albumin Bilirubin Prothrombin time Ascites Encephalopathy Ref: Sabiston 20th edition Pgno : 1436
2
Encephalopathy
ALT
Ascites
Albumin
Anatomy
G.I.T
165851d6-7384-4ba6-b3de-0b316916f412
single
Which of the following will be detected in flow cytometry?
Flow cytometry is an extremely useful investigational tool that allows simultaneous multiparametric analysis of the physical characteristics defining WBC types using the principles of light scattering, excitation, and fluorochrome emission. As such, it can allow for the rapid identification and quantification of popula...
3
Polycythemia
Thrombocytosis
Leukocytosis
Neutrophilia
Pathology
null
e70f2664-b75a-4182-bf81-5015033a6cd1
single
Base of the skull fracture presents with involvement of the petrous temporal bone, which of the following important sign:
(Battle sign) (595-Baily & Love 24th) (302-B &L 25th)Base of Skull Fractures* Anterior fossa fracture - May open into the frontal or ethmoid air sinuses or run across the cribriform plate.* Presents with sub conjunctival hematoma, anosmia, epistaxis, nasal tip anaesthesia, CSF-rhinorrhea and occasionally carotico-caver...
4
Subconjunctive haematoma
CSF rhinorrhoea
Raccon eyes
Battle sign
Surgery
Trauma
c229d52d-be85-428a-832c-bb708bb81c85
single
Which of the following pubeal events in girls is not estrogen dependant
Functions of estrogen Estrogen changes the vaginal epithelium from cuboidal to stratified type,which is more resistant to trauma and infection Marked proliferation of endometrial stroma and greatly increases the development of the endometrial glands - Menstruation Development of the stromal tissue of breast, growth of ...
4
Menstruation
Vaginal cornification
Height spu
Hair growth
Gynaecology & Obstetrics
Congenital malformations
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single
A pathologist is observing a slide. He repos seeing perineural invasion. In which one of the following perineural invasion is most commonly seen?
Adenoid cystic carcinoma
2
Adenocarcinoma
Adenoid cystic carcinoma
Basal Cell Adenoma
Squamous cell carcinoma
ENT
null
aee22d6a-4192-4814-9e65-cd42d225103c
single
All of the following investigations are used in FIGO staging of carcinoma cervix except ?
CECT According to the FIGO guidlines for clinical staging of cervical carcinoma, diagnostic studies include :-Intravenous urography (pyelography). - Cystoscopic examination of bladder and urethra Proctosigmoidoscopic study - Barium enema Colposcopic study of the vagina and vaginal formices in early stage disease. Colpo...
1
CECT
Intravenous pyelography
Cystoscopy
Proctoscopy
Surgery
null
9f60920e-092d-4498-bcd0-ea2b487745d8
multi
True regarding febrile convulsion –
Types of febrile convulsions Febrile convulsions may be of two types. Simple benign Atypical complex 1. Simple benign febrile convulsions More common                                                            Last less than 10 minutes       Convulsions are generalized       No post ictal neurological deficit    Us...
2
Carbamazepine is good drug to treat it
Patient with family h/o F.C. have increased incidence of recurrence
Longterm neurological deficits are common
Usually last for short while
Pediatrics
null
ed3b1bb6-eaf6-46a2-864b-705bc93eb480
multi
Uterine-cervix ratio up to 10 years of age:
The relationship of the length of the cervix and that of the body of uterus varies with age.
4
3:02
2:01
3:01
1:02
Gynaecology & Obstetrics
null
02cc6c53-430f-4db9-93b2-b248cb047b70
single
Which of the following is produced in the lipoxygenase pathway?
Thromboxane A2, prostacyclin, and prostaglandins are formed by the cyclooxygenase pathway whereas leukotrienes are formed by the lipooxygenase pathway.Ref: Textbook of medical physiology by N Geetha, 2nd edition, page no. 103
2
Thromboxane
Leukotrienes
Prostaglandin
Prostacyclin
Physiology
Cardiovascular system
39abce09-81b3-4c41-bb22-021947a4ecec
single
Apparent volume of distribution (aVd) is more than total body fluid if drug is:
null
2
Poorly soluble
Sequestered in tissues
Slow elimination
Poorly plasma protein bound
Pharmacology
null
c06c3651-0395-4031-a873-2dd88c460ff2
single
Deleterious effect of ultrasound on small organism is:
Ans. Cavitation
3
Ionisation
Vacoulation
Cavitation
Disintegration
Radiology
null
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multi
Hemophia A due to deficiency of ?
Ans. is 'a' i.e., Factor VIII Hemophila A :? Hemophilia A is due to deficiency of factor VIII. Hemophilia A is inherited as an X-linked recessive trait. Factor VIII is an intrinsic pathway component required for activation of factor X. Clinical manifestations are due to defect in coagulation system :- Large post trauma...
1
Factor VIII
Factor IX
Factor X
Factor XI
Pathology
null
b191de22-3c90-42ea-96c9-84cdc5931a9c
single
V/Q ratio at the base of lung-
Ans. is 'c' i.e., 0.6 o Overall V/Q ratio of lung-0.8o V/Q ratio at apex-3.0 (maximum)o V/Q ratio at base-0.6 (Least)
3
1
3
0.6
1.8
Physiology
Mechanics of Respiration
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single
A 70 year old man develops pneumonia and septicemia. Patient goes into renal failure and has a BP of 70/50 mm of Hg. Drug that should be used to maintain BP is:
Answer is D (Norepinephrine) The patient in question is presenting with features of septic shock. Dopamine is the initial recommended vasopressor agent to maintain blood pressure but is not provided amongst the options. Patients who remain hypotensive despite dopamine should he adminstered norepinephrine and hence nore...
4
Adrenaline
Ephedrine
Phenylephrine
Nor epinephrine
Medicine
null
16455382-2e31-4a2e-a0dc-6f3e602e394c
single
To be defined as a ganglioside,a lipid substance isolated from nervous tissue must contain
Gangliosides are the complex glycosphingolipids derived from glucosylceramide that contain in addition one or more molecules of sialic acid. Neuraminic acid is the principal sialic acid found in human tissues. Gangliosides are present in nervous tissue in high concentration.They help in cell-cell recognition and commun...
4
NANA,hexose,fatty acid,glycerol
NANA,hexose,fatty acid,phosphorycholine
NANA,sphingosine,ethanolamine
NANA,hexose,sphingosine,long chain fatty acid,
Biochemistry
Metabolism of lipid
b39a2732-b939-4b98-93f5-a4c3b972718e
single
A 25 years old female complains of recurrent rhinitis, nasal discharge and bilateral nasal blockage since one year. She has the history of asthma and allergy. On examination, multiple ethmoidal polyps are noted with mucosal thickening and impacted secretions in both the nasal cavities. A biopsy is taken and the materia...
Aspergillus shows typical dichotomous branching at an angle of approximately 45degrees. Candida shows pseudohyphae. Rhizopus and mucor shows nonseptate hyphae. Reference: Textbook of Microbiology; Baveja; 4th edition
1
Aspergillus fumigatus
Rhizopus
Mucor
Candida
Microbiology
mycology
daf61c69-6951-485c-b98e-5e85aa3c5120
multi
Blood for acid base gas (ABGO analysis in a bottle containing heparin can cause decreased value of -
null
3
pCO2
HCO2
pH
pO2
Medicine
null
35361b14-3f71-4a72-bfd0-db12c3e48990
single
Boerhaave syndrome is due to:
Ans. (b) vomitingRef Bailey and Love 27th edition, Page 1073* Vomiting against closed Glottis leads to Boerhaave syndrome.* Vomiting against closed LES leads to Mallory Weiss tear.
2
Burns
Vomiting
Stress
Acid ingestion
Surgery
Oesophagus
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single
In anemia the concentration of 2,3 DPG is
null
2
Decreased
Increased
A or B
Not changed
Physiology
null
2ebdf84e-bb0b-4548-a606-5df2fa294c21
single
The primary reason for replacing teeth destroyed due to nursing bottle syndrome is
null
1
Speech and esthetics
Form and function
Incising and mastication
Arch perimeter requirements in the transitional dentition
Dental
null
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single
Characteristic histopathology finding in Whipples disease is ?
Ans. is 'a' i.e., PAS positive macrophages and rod shaped bacilli in lamina propriaThe hallmark of Whipple's disease is a small intestinal mucosa laden with distended macrophages in the lamina propria- the macrophages contain periodic acid-schiff (PAS) positive granules and rod shaped bacilli by electron microscopy.Thr...
1
PAS positive macrophages and rod shaped bacilli in lamina propria
Shoened thickened villi with increased crypt depth
Blunting and flattening of mucosal surface and absent villi
Mononuclear infiltration at base of crypts
Pathology
null
a3cac66c-18c3-417e-be03-92053685efcb
single
In which of the following conditions uniform dilation of esophagus is seen
In Trypanosoma cruzi infection& dermatomyositis uniform dilatation of oesophagus is seen Esophageal dilatation is a therapeutic endoscopic procedure that enlarges the lumen of the esophagus. ...Complications of esophageal dilatation include the following: Odynophagia, or painful swallowing. Hematemesis, or bloody vomit...
4
Scleroderma
Trypanosoma cruzi infection
Dermatomysitis
BD
Pathology
G.I.T
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single
Mechanism of action of vincristine in the treatment of ALL is:
Vinca alkaloids like vincristine and vinblastine act by inhibiting the formation of mitotic by spindle inhibiting polymerization of tubulin. These drugs are selective for M phase of cell cycle.
4
Inhibition of topoisomerase II to cause breaks in DNA strands
Alkylation and cross linking DNA strands
Inhibition of DNA mediated RNA synthesis
Inhibition of polymerization of tubulin to form microtubules
Pharmacology
Cytotoxic Anticancer Drugs
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multi
All are true about ketone bodies except
KETOSIS Under ceain metabolic conditions associated with a high rate of fatty acid oxidation, liver produces considerable quantities of compounds like acetoacetate and bbb-OH butyric acid, which pass by diffusion into the blood. Acetoacetate continually undergoes spontaneous decarboxylation to produce acetone. These th...
4
Acetoacetate is primary ketone body
Synthesized in mitochondria
Synthesized in liver
HMG CoA reductase is the rate-limiting enzyme
Biochemistry
Metabolism of lipid
da1622c6-0278-437f-872c-c897f740b90d
multi
Pseudoparalysis in an infant is suggestive of ?
Ans. is 'd' i.e., Vit C deficiencyPseudoparalysis o A voluntary restriction of motion because of pain, incordination or other cause, but not due to actual muscular paralysis.Causes of pseudoparalysisScurvy (vitamin C deficiency) o OsteomyelitisSeptic (ahritis) o Congenital syphilis
4
Acute Rheumatic fever
Vitamin B6 deficiency
Vitamin E deficiency
Vitamin C deficiency
Pediatrics
null
94cf51ff-edd8-40d2-94ef-5f477abbf0aa
single
The coronoid process:
null
2
Limits the extension of maxillary posterior teeth setting
Limits the thickness of the distobuccal flange of the upper complete denture
Limits the thickness of the distobuccal flange of the lower complete denture
Determines PPS
Dental
null
f3f895ea-7b72-406e-af9d-b29387b0d979
single
Greater than 30 g of fat is excreted in feces per day. The cause is
(A) Exocrine pancreatic insufficiency # Steatorrheal causes:> Intraluminal maldigestion (pancreatic exocrine insufficiency, bacterial overgrowth, bariatric surgery, liver disease)> Mucosal malabsorption (celiac sprue, Whipple's disease, infections, abetalipoproteinemia, ischemia)> Postmucosal obstruction (1deg or 2deg ...
1
Exocrine pancreatic insufficiency
Rapid transient diarrhea
Small intesitnal disease
Normal
Pathology
Misc.
a9427166-29bc-4d46-a2bb-a7ced06ef173
multi
A young girl has had repeated infections with Candida albicans and respiratory viruses since she was 3 months old. As part of the clinical evaluation of her immune status, her responses to routine immunization procedures should be tested. In this evaluation, the use of which of the following vaccines is contraindicated...
Recurrent severe infection is an indication for clinical evaluation of immune status. Live vaccines, including BCG attenuated from M. tuberculosis, should not be used in the evaluation of a patient's immune competence because patients with severe immunodeficiencies may develop an overwhelming infection (disseminated di...
1
Bacillus Calmette-Guerin (BCG)
Bordetella pertussis vaccine
Diphtheria toxoid
Inactivated polio
Microbiology
Immunology
6b6f4c68-54e2-4ddc-9957-d9375d57a913
single
All of the following are in the superficial perineal space of the male EXCEPT the
The bulbourethral (Cowper's) gland is in the deep penineal space within the urogenital diaphragm. The duct from the gland leaves the deep perineal space, enters the superficial penineal space, and then enters the urethra. Because the gland is in the deep perineal space within a tightly confined area, infection of the g...
3
Bulb of the penis
Crus of the penis
Bulbourethral gland
Bulbospongiosus muscle
Anatomy
null
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multi
A 62-year-old man is admitted to the hospital with dull, diffuse abdominal pain. A CT scan reveals a tumor at the head of the pancreas. The abdominal pain is mediated by afferent fibers that travel initially with which of the following nerves?
The afferent fibers mediating the pain from the head of the pancreas run initially with the greater thoracic splanchnic nerves. The greater splanchnic nerves arise from sympathetic ganglia at the levels of T5 to T9 and innervate structures of the foregut and thus the head of the pancreas. Running within these nerves ar...
1
Greater thoracic splanchnic
Intercostal
Phrenic
Vagus
Anatomy
Abdomen & Pelvis
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multi
Advantage of Minimal access surgery
The core principles of minimal access surgery (independent of procedure or device) can be summarized by the acronym I-VITROS: * Insufflate/create space - to allow surgery to take place in the minimal access setting * Visualise - the tissues, anatomical landmarks and the environment for the surgery to take place * Ident...
3
Heat loss
Better Hemostasis control
Improved vision
In wound pain
Surgery
Urology
ba11861d-197d-4932-b4c7-aa3de8adf917
single
Pinch purpura is diagnostic of –
In primary systemic amyloidosis amyloid deposition occurs in the wall of the blood vessels, this leads to an increase in skin fragility. As a result, petechiae and purpura develop in clinically normal skin as well as in lesional skin following minor trauma. Therefore the skin lesions in case of primary systemic amyloid...
1
Systemic primary amyloidosis
Secondary systemic amyloidosis
Idiopathic thrombocytopenic purpura
Drug induced purpura
Dental
null
60a6d914-4a54-4e55-bb46-c9a2a50df228
single
The mode of action of Lanatoprost in glaucoma:
Lantanoprost is prastoglandin in nature and decrease the intraocular pressure by increasing uveoscleral outflow of aqueous humour. It is very good adjunctive therapy along with betablockers, dorzolamide and pilocarpine. Ref: A.K KHURANA (2005), Chapter 9, "Glaucoma", In the book, "Opthalmology", 3rd Edition, Newdelhi, ...
4
Increasing trabecular outflow
Releasing pupillary block
Decreasing aqueous humour formation
Increasing uveoscleral outflow
Ophthalmology
null
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single
Gelle&;s test is done in
Gelle's test: It is also a test of bone conduction and examines the effect of increased air pressure in ear canal on the hearing. Normally, when air pressure is increased in the ear canal by Siegel's speculum, it pushes the tympanic membrane and ossicles inwards, raises the intralabyrinthine pressure and causes immobil...
1
Otosclerosis
Serous otitis media
Traumatic deafness
Senile deafness
ENT
Ear
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Factor responsible for Cardiac Hyperophy is?
Ans. is 'c' i.e., c-myc
3
ANF
TNF alpha
c-myc
TGF beta
Pathology
null
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Most common cause of gangrene of foot of a 30 year old farmers who is a chronic smoker
All four can cause gangrene (Myocardial infarction can cause gangrene by thromboembolism) Lets see, each option one by one. Raynauds disease Is ds of young women* (F:M ratio is 5:1) commonly the upper limbs* are affected specially the fingers (the thumb is generally escaped) The disease is characterized by Raynauds phe...
3
Atherosclerosis
Raynaud's disease
Thromboangiitis obliterans
Myocardial infarction
Surgery
Vascular surgery
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Following features are true about lipid insoluble beta blockers except?
Ans. is `b' i.e., Have good membrane stabilizing effect Lipid insolubile drugs have following features ? Do not cross Blood Brain Barrier and therefore produce no CNS effects. Have good renal excretion Have no membrane stabilizing activity Are incompletely absorbed orally Are long acting Are effective in narrow dose ra...
2
Do not cross blood brain barrier
Have good membrane stabilizing effect
Incompletely absorbed orally
Are long acting
Pharmacology
null
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Sideroblastic anemia is seen in chronic poisoning of
Ans. (a) Lead(Ref: Wintrobe's 12th/pg837)Sideroblastic anemia is seen in:*. Alcoholism*. Lead poisoning*. Drugs (isoniazid, pyrazinamide, chloramphenicol)*. Copper deficiency (zinc ingestion, copper chelation, nutritional, malabsorption)*. Hypothermia
1
Lead
Arsenic
Copper
Mercury
Pathology
Misc. (R.B.C)
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"Lift off' and "Belly Press" tests are done to examine which of the following rotator cuff muscle?
Ans. C. SubscapularisSubscapularis muscle is responsible for extremes of internal rotation, which can be tested with belly press and lift off test.
3
Teres Minor
Supraspinatus
Subscapularis
Infraspinatus
Orthopaedics
Injuries Around Shoulder
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Superior Gluteal Nerve supplies ail except:
Ans. C. Gluteus MaximusThe superior gluteal nerve arises from the sacral plexus in the pelvis and is formed by the dorsal branches of the ventral rami of L4, L5; S1. It enters the gluteal region through the greater sciatic notch above the piriformis in company with superior gluteal artery. Here it curves upward and for...
3
Gluteus Minimus
Gluteus Medius
Gluteus Maximus
Tensor Fascia Lata
Anatomy
Lower Extremity
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Placental abnormality related to PPH is?
Ans. is 'd' i.e., All the abovePlacenta: morbidly adherent placenta (accrete, percreta), paially or completely separately separated placenta but with retained bits of placental tissue leads to PPH.
4
Placenta accreta
Placenta percreta
Retained placental
All the above
Gynaecology & Obstetrics
null
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multi
What is the amount of time required by erupting premolar to move through 1 mm of bone as measured on a bite-wing radiograph?
null
2
3-4 months
4-5 months
5-6 months
6-7 months
Dental
null
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Best method to show trend of events with passage of time is?
ANSWER: (A) Line diagramREF: Park 20th edition page 747 &748, style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif; margin: 0 0 0 8px; text-indent: 0; text-align: left">"Line diagrams are used to show the trend of events with passage of time"PictographA pictograph uses an icon to represent a...
1
Line diagram
Bar diagram
Histogram
Pie chart
Social & Preventive Medicine
Data Variables
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More resistance in expiration is due to:
A i.e. Increased compression of airways
1
Increased compression of airway
Due to change from linear to turbulent flow
Saturation with moisture
Increased rate of flow during expiration
Physiology
null
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Antihypertensive may act by blocking all of following except:
null
2
Alpha–adrenoceptors
ATP dependent K+ channels
Nor adrenaline release
Beta adrenoceptors
Pharmacology
null
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Temporal pallor in optic disc seen in all except
Optic atrophy, pallor of the optic nerve head, is a sign found in patients with visual loss due to pathology of the optic nerve or retinal ganglion cells. ... It refers topallor of the optic disc which results from irreversible damage to the retinal ganglion cells and axons. It is commonly seen in Optic neuritis Compre...
4
Optic neuritis
Compression of optic nerve
Leber's hereditary optic neuritis
Glaucoma
Ophthalmology
Vitreous and retina
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Anti glaucoma drug that act by increasing uvea scleral outflow is?
REF : KD TRIPATHI 8TH ED
1
Latanoprost
Timolol
pilocarpine
Dorzolamide
Pharmacology
All India exam
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single
The major vitamin deficiency in Wernicke's encephalopathy is :
Wernicke's disease is a common and preventable disorder due to a deficiency of thiamine. Alcoholics account for most cases, but patients with malnutrition due to hyperemesis, starvation, renal dialysis, cancer, AIDS, or rarely gastric surgery are also at risk. The characteristic clinical triad is that of ophthalmoplegi...
1
B1
B2
B6
B12
Biochemistry
null
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Commonest fungal infection of female genitalia in diabetes?
Candida is the commonest infection of female genital tract in diabetes. Candida species are normal commensals of the mouth, GI tract, vaginal mucosa and in the patients with an indwelling catheter. Diabetes is paicularly associated with increased susceptibility to vaginal infections.
3
Cryptococcal
Madurmycosis
Candida
Aspergillosis
Dental
Fungal infections
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Who among the following has contributed to the development of neuro-otology and is considered as the father of 'nen ro-otology'?
Ans. c. William F. House (Ref www.audiology.org For the pioneering work in the field of neuro-otology, William F. House considered as 'Father of Neuro-otology'. William F. House considered as 'Father of Neuro-otology' because of his pioneering development approaches for the removal of acoustic tumors and the management...
3
Julius Lampa
John J. Shea Jr
William F. House
Hales Main
ENT
null
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Drugs causing macular toxicity when given intravitreally-
Ans. is 'a' i.e., Gentamycino Intravitreal aminoglycosides (gentamycin, amikacin) are a reported cause of macular toxicity.o Aminoglycosides induced macular toxicity is thought to be partially due to the gravity-induced settling of drugs on the macula in supine position.o This may result in a higher concentration of dr...
1
Gentamycin
Vancomycin
Dexamethasone
Ceftazidime
Ophthalmology
Drugs
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Fatty liver is caused by all except
Fatty change in the liver may result from one of the two types of causes: 1.Conditions with excess fat: i) Obesity ii)Diabetes mellitus iii)Congenital hyperlipidaemia 2.Liver cell damage: i) Alcoholic liver disease (most common) ii)Starvation iii)Protein calorie malnutrition iv)Chronic illnesses (e.g. tuberculosis) v) ...
4
DM
Tetracycline
Starvation
Excess iron intake
Pathology
G.I.T
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Urination in the human subject is decreased by
ANTICHOLINERGIC DRUGS (Muscarinic receptor antagonists, Atropinic, Parasympatholytic) Smooth muscles:- All visceral smooth muscles that receive parasympathetic motor innervation are relaxed by atropine (M3 blockade). Tone and amplitude of contractions of stomach and intestine are reduced; the passage of chyme is slowed...
4
Nicotinic agonists
AChase inhibitors
muscarinic agonists
muscarinic antagonists
Pharmacology
Autonomic nervous system
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Intraepidermal lgG deposition is seen in
Pemphigus
1
Pemphigus
Bullous pemphigoid
Herpes genitalis
SLE
Skin
null
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single
More resistance in respiration is due to which of the following?
More resistance in respiration is seen in bronchial construction Ref: guyton and hall textbook of medical physiology 12 edition page number:333,334,335
3
Saturation with moisture
Increased rate of flow during expiration
Increased compression of airway
Due to change from linear to turbulent flow
Physiology
Respiratory system
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A patient presented with fever, cervical lymphadenopathy and night sweats four weeks after unprotected sexual contact. Next investigation
Ref: PubMed* This is a possible suspicion of HIV infection.* p24 antigen is a viral protein that makes up most of the viral core.* Serum concentrations of p24 antigen are high in the first few weeks after infection; tests sensitive to p24 antigen are therefore useful for diagnosing very early infection when antibody le...
1
p24
ELISA
CD4
HIV PCR
Microbiology
Virology
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Apical root fracture in an anterior tooth is treated by:
A tooth with its root fractured in its apical third has an excellent prognosis because the pulp in the apical fragment usually remains vital, and the tooth may remain firm in its socket.  A mobile tooth should be splinted.  If the pulp in the coronal fragment remains vital and the tooth is stable, with or without ligat...
4
Extraction
Splinting for 2-3 months
Endodontic treatment
All of the above
Dental
null
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multi
Neonatal Jaundice first time appears in the 2nd week not a cause is –
null
2
Galactossemia
Rh Incompatibility
Hypothyroidism
Breast milk Jaundice
Pediatrics
null
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Optical media are clear in:
Ans. Both of the above
3
Cavernous sinus thrombosis
Orbital cellulitis
Both of the above
None of the above
Ophthalmology
null
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A male was brought unconscious to the hospital with external injuries. CT shows no midline shift, but basal cisterns were full (compressed) with multiple small haemorrhage. The most probable diagnosis is:
B i.e. Diffuse axonal injuries Diffuse axonal injuries (DAI) - shearing injuries caused by sudden rotational or accelerating / decelerating forces. Patient typically lose consciousness at the time of impactQ. On CT small petechial hemorrhages are seenQ
2
Brain contusion
Diffuse axonal injury
Subdural hemorrhage
Multiple infarct
Radiology
null
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The patient is delivered by cesarean section under general anesthesia.The baby and placenta are easily delivered, but the uterus is noted to be boggy and atonic despite intravenous infusion of Pitocin. All of the following are appropriate agents to use next except
Methylergonovine, prostaglandin F2α, prostaglandin E1 (Misoprostil), and prostaglandin E2 (Hemabate)are all uretotonic agents than can be used in situations where there is a postpartum hemorrhage due to uterine atony. Terbutalinewould be contraindicated in this situation because it is a tocolytic that is used to promot...
4
Methylergonovine (Methergine) administered intramuscularly
Prostaglandin F2α (Hemabate) suppositories
Misoprostil (Cytotec) suppositories
Terbutaline administered intravenously
Unknown
null
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Unwinding Enzyme in DNA synthesis:
Ans. A. Helicase(Ref: Harper 31/e page 364)Classes of proteins involved in DNA replicationProteinFunctionDNA polymerasesDeoxynucleotide polymerizationHelicasesProcessive unwinding of DNATopoisomerasesRelieve torsional strain that results from helicase-induced unwindingProteinFunctionDNA primaseInitiates synthesis of RN...
1
Helicase
Primase
DNA Polymerase
Transcriptase
Biochemistry
Molecular Genetics
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Most common pa of larynx involved in Tuberculosis is
Tubercular laryngitisThe disease affects the posterior third of larynx more commonly than anterior paThe pas affected in descending order of frequency are:- i) Interarytenoid fold, ii) Ventricular band, iii) Vocal cords, iv) EpiglottisRef: PL Dhingra, Diseases of Ear, Nose & Throat, 7th edition, pg no. 329 - 330
2
Anterior
Posterior
Middle
Anywhere
ENT
Larynx
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single
Which bacteria has Ampitrichous flagella
Mono - trichous - V.cholerae Ampitrichous  - Alcaligenes faecalis Lophotrichous  - Spirillum minus Peritricous  - E.coli, proteus, Listeria
4
V cholerae
Spirillum minus
Listeria
Alcaligenes faecalis
Microbiology
null
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single
Hemolytic uremic syndrome is caused by
Shigella dysenteriae type 1 causes toxemia due to the production of exotoxin.the complication includes polyneuritis, ahritis, conjunctivitis, parotitis and hemolytic uremic syndrome. Ref: Textbook of microbiology; Ananthanarayan and paniker's;10th edition; Pg:293
2
EIEC
Shigella
Salmonella
Cholera
Microbiology
Bacteriology
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Liposomal amphotericin B has the following advantage over conventional amphotericin B:
Amphotericin B (AMB): It is obtained from Streptomyces nodosus. Chemistry and mechanism of action The polyenes possess a macrocyclic ring, one side of which has several conjugated double bonds and is highly lipophilic, while the other side is hydrophilic with many OH groups. A polaraminosugar and a carboxylic acid grou...
1
Lesser nephrotoxicity
Lesser cost
Absense of infusional toxicity
Once a week administration
Pharmacology
Chemotherapy
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Which of the following is false regarding neoplastic compressive myelopathy?
Any malignant tumour can metastasise to spinal columns, paicularly tumours of breast, lung, prostate, kidney, lymphoma and myeloma. The most common site is the thoracic spinal column. Most neoplasms are epidural in origin, resulting from metastases to adjacent veebral body. Unlike infections of the spinal column, the t...
1
Most neoplasms are subdural in origin
Thoracic spine is most commonly involved
Tumor does not cross the disk space to involve adjacent veebral body
Prognosis is poor when motor deficits are established for > 48 hours
Medicine
All India exam
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multi
In which of the following patients would enalapril be the best first line agent for high blood pressure control ?
null
4
A 62 year old man with renal artery stenosis
A 32 year old pregnant female
A 41 year old woman with hyperkalemia
A 56 year old diabetic woman
Pharmacology
null
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single
An eight year old child has active white spot lesions on his teeth and gives a history of having sugar containing snacks and beverages more than 3 times in between meals. In which category can we classify this child
Caries-Risk Assessment Form for Children 6 Years Old or Younger
1
High Risk
Moderate Risk
Low Risk
None
Dental
null
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multi
Which of the following generations of amalgam exhibit highest nobility?
The set amalgam exhibits the highest nobility of any previous amalgam and has been the most recent 6th generation of amalgam to be developed. Reference: Marzouk Operative dentistry, pg-106
4
3rd generation amalgam
4th generation amalgam
5th generation amalgam
6th generation amalgam
Dental
null
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single
A patient of Schizophrenia was staed on neuroleptics, his psychotic symptoms began to improve however he developed sadness, would talks less to others, would mostly remain to bed. This presentation could be caused by all of following except:
This question is basically asking for the differential diagnosis of symptoms of ' sadness of mood, talking less and staying on the bed" in a patient of schizophrenia who has been staed on antipsychotics. 1. The sadness of mood and decreased interaction can be of course due to depression 2. Negative symptoms of schizoph...
4
Parkinsonism
Major depression
Negative symptoms are still persisting
He is reacting to external stimuli
Psychiatry
Schizophrenia Spectrum and Other Psychotic Disorders
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The location of schatzki&;s ring is
SCHATZKI'S RING It occurs at the junction of squamous and columnar epithelium at the lower end of oesophagus and has also been called lower oesophageal ring. Usually seen in patients above 50 years of age. Cause is unknown. Symptomatic patients complain of intermittent dysphagia and some may even present with bolus obs...
3
Lower end of pharynx
Upper end of esophagus
Lower end of esophagus
Antrum of stomach
ENT
Oral cavity & Oesophagus
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Prolactin:
Prolactin, though structurally related to growth hormone does not share its somatotropic activity. Dopamine binds to the lactotropes and inhibits the synthesis and release of prolactin. Hyperprolactinemia suppresses the hypothalamic-pituitary-gonadal axis, causes infertility in women and suppresses the normal menstrual...
3
Has somatotropic activity.
It flow can cause infertility in women.
Can suppress menstrual cycle in lactating women.
Levels are increased by dopamine.
Pharmacology
null
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single
Triplet repeats in Fragile X -syndrome is?
DISORDER TRIPLET REPEATS Fragile X syndrome CGG Friedreich ataxia GAA Myotonic dystrophy CTG Huntington disease CAG Ref: Nelson, 18th Edition, Pages 135, 499
2
CTG
CGG
CAG
GAA
Pediatrics
null
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single
Left Kidney is preferred for transplantation because
The left kidney is preferred because of implantation advantages associated with a longer renal vein making anastomosis easier Also know, procurement of kidney, In a brainstem dead donor, the organ to be procured should be preserved to maintain its functional integrity. For this purpose the organ should be perfused with...
1
Longer renal Vein
Higher location
Ease of surgery due to anatomical relations
To prevent damage to liver
Anatomy
Urology
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single
Cesarean section is absolutely indicated in :
Type IV placenta pre
2
Previous H/0 LSCS
Type IV placenta pre
Type II placenta pre
Past H/o hysterotomy
Gynaecology & Obstetrics
null
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single
In a dead body recovered from an open field, the below finding is seen. What could be the time since death:
Ans. (B). 3 - 5 daysPeeling of skin is a sign of decomposition.Skin slippage is noted on 2 -3 days,Degloving & destocking type of peeling -3-5 days.This type of change is also seen in drowning.The degloved skin can be preserved in formalin and used for fingerprint analysis.
2
24- 36 hrs
3- 5 days
5-10 days
More than 2 weeks
Forensic Medicine
Injuries
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