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Concepts of Biology SENIOR CONTRIBUTING AUTHORS SAMANTHA FOWLER, CLAYTON STATE UNIVERSITY REBECCA ROUSH, SANDHILLS COMMUNITY COLLEGE JAMES WISE, HAMPTON UNIVERSITY [Image OCR Text] tax” au = §=opens
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Contents Preface 1 UNIT 1 THE CELL ULAR FOUNDATION OF LIFE CHAP TER 1 Introduction to Biology 5 Introduction 5 1.1Themes and Concepts of Biology 5 1.2The Process of Science 16 Key Terms 24 Chapter Summary 24 Visual Connection Questions 25 Review Questions 25 Critical Thinking Questions 26 CHAP TER 2 Chemistry of Life 27 Introduction 27 2.1The Building Blocks of Molecules 28 2.2Water 34 2.3Biological Molecules 39 Key Terms 51 Chapter Summary 52 Visual Connection Questions 53 Review Questions 53 Critical Thinking Questions 54 CHAP TER 3 Cell Structure and Function 55 Introduction 55 3.1How Cells Are Studied 55 3.2Comparing Prokaryotic and Eukaryotic Cells 59 3.3Eukaryotic Cells 61 3.4The Cell Membrane 74 3.5Passive Transport 76 3.6Active Transport 80 Key Terms 84 Chapter Summary 85 Visual Connection Questions 87 Review Questions 87 Critical Thinking Questions 88
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CHAP TER 4 How Cells Obtain Energy 89 Introduction 89 4.1Energy and Metabolism 90 4.2Glycolysis 100 4.3Citric Acid Cycle and Oxidative Phosphorylation 101 4.4Fermentation 105 4.5Connections to Other Metabolic Pathways 108 Key Terms 110 Chapter Summary 111 Visual Connection Questions 112 Review Questions 112 Critical Thinking Questions 113 CHAP TER 5 Photosynthesis 115 Introduction 115 5.1Overview of Photosynthesis 115 5.2The Light-Dependent Reactions of Photosynthesis 120 5.3The Calvin Cycle 124 Key Terms 129 Chapter Summary 129 Visual Connection Questions 130 Review Questions 130 Critical Thinking Questions 130 UNIT 2 CELL DIVISION AND GENET ICS CHAP TER 6 Reproduction at the Cellular Level 133 Introduction 133 6.1The Genome 133 6.2The Cell Cycle 135 6.3Cancer and the Cell Cycle 141 6.4Prokaryotic Cell Division 142 Key Terms 146 Chapter Summary 147 Visual Connection Questions 148 Review Questions 148 Critical Thinking Questions 149 CHAP TER 7 The Cellular Basis of Inheritance 151
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Key Terms 146 Chapter Summary 147 Visual Connection Questions 148 Review Questions 148 Critical Thinking Questions 149 CHAP TER 7 The Cellular Basis of Inheritance 151 Introduction 151 7.1Sexual Reproduction 152 7.2Meiosis 155 7.3Variations in Meiosis 160 Key Terms 167 Chapter Summary 167 Access for free at openstax.org
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Visual Connection Questions 168 Review Questions 168 Critical Thinking Questions 169 CHAP TER 8 Patterns of Inheritance 171 Introduction 171 8.1Mendel’s Experiments 172 8.2Laws of Inheritance 176 8.3Extensions of the Laws of Inheritance 183 Key Terms 192 Chapter Summary 192 Visual Connection Questions 193 Review Questions 194 Critical Thinking Questions 195 UNIT 3 MOLECUL AR BIOLOGY AND BIOTECHNOLOGY CHAP TER 9 Molecular Biology 197 Introduction 197 9.1The Structure of DNA 198 9.2DNA Replication 202 9.3Transcription 209 9.4Translation 212 9.5How Genes Are Regulated 215 Key Terms 219 Chapter Summary 220 Visual Connection Questions 221 Review Questions 221 Critical Thinking Questions 222 CHAP TER 10 Biotechnology 223 Introduction 223 10.1Cloning and Genetic Engineering 223 10.2Biotechnology in Medicine and Agriculture 231 10.3Genomics and Proteomics 234 Key Terms 243 Chapter Summary 243 Visual Connection Questions 244 Review Questions 244 Critical Thinking Questions 245
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10.3Genomics and Proteomics 234 Key Terms 243 Chapter Summary 243 Visual Connection Questions 244 Review Questions 244 Critical Thinking Questions 245 UNIT 4 EVOLUTION AND THE DIVERSI TY OF
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LIFE CHAP TER 11 Evolution and Its Processes 247 Introduction 247 11.1Discovering How Populations Change 248 11.2Mechanisms of Evolution 254 11.3Evidence of Evolution 256 11.4Speciation 259 11.5Common Misconceptions about Evolution 264 Key Terms 268 Chapter Summary 268 Visual Connection Questions 269 Review Questions 269 Critical Thinking Questions 271 CHAP TER 12 Diversity of Life 273 Introduction 273 12.1Organizing Life on Earth 273 12.2Determining Evolutionary Relationships 278 Key Terms 285 Chapter Summary 285 Visual Connection Questions 286 Review Questions 286 Critical Thinking Questions 286 CHAP TER 13 Diversity of Microbes, Fungi, and Protists 287 Introduction 287 13.1Prokaryotic Diversity 288 13.2Eukaryotic Origins 298 13.3Protists 300 13.4Fungi 306 Key Terms 315 Chapter Summary 316 Visual Connection Questions 317 Review Questions 317 Critical Thinking Questions 318 CHAP TER 14 Diversity of Plants 319 Introduction 319 14.1The Plant Kingdom 320 14.2Seedless Plants 326
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Visual Connection Questions 317 Review Questions 317 Critical Thinking Questions 318 CHAP TER 14 Diversity of Plants 319 Introduction 319 14.1The Plant Kingdom 320 14.2Seedless Plants 326 14.3Seed Plants: Gymnosperms 333 14.4Seed Plants: Angiosperms 338 Key Terms 347 Chapter Summary 348 Access for free at openstax.org
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Visual Connection Questions 348 Review Questions 349 Critical Thinking Questions 349 CHAP TER 15 Diversity of Animals 351 Introduction 351 15.1Features of the Animal Kingdom 352 15.2Sponges and Cnidarians 357 15.3Flatworms, Nematodes, and Arthropods 363 15.4Mollusks and Annelids 370 15.5Echinoderms and Chordates 376 15.6Vertebrates 380 Key Terms 390 Chapter Summary 392 Visual Connection Questions 394 Review Questions 394 Critical Thinking Questions 395 UNIT 5 ANIMAL S TRUCTURE AND FUNCT ION CHAP TER 16 The Body’s Systems 397 Introduction 397 16.1Homeostasis and Osmoregulation 398 16.2Digestive System 402 16.3Circulatory and Respiratory Systems 408 16.4Endocrine System 414 16.5Musculoskeletal System 420 16.6Nervous System 426 Key Terms 436 Chapter Summary 438 Visual Connection Questions 441 Review Questions 441 Critical Thinking Questions 443 CHAP TER 17 The Immune System and Disease 445 Introduction 445 17.1Viruses 446 17.2Innate Immunity 453 17.3Adaptive Immunity 456
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Review Questions 441 Critical Thinking Questions 443 CHAP TER 17 The Immune System and Disease 445 Introduction 445 17.1Viruses 446 17.2Innate Immunity 453 17.3Adaptive Immunity 456 17.4Disruptions in the Immune System 465 Key Terms 469 Chapter Summary 470 Visual Connection Questions 471 Review Questions 471 Critical Thinking Questions 472
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CHAP TER 18 Animal Reproduction and Development 473 Introduction 473 18.1How Animals Reproduce 474 18.2Development and Organogenesis 478 18.3Human Reproduction 480 Key Terms 491 Chapter Summary 492 Visual Connection Questions 493 Review Questions 493 Critical Thinking Questions 494 UNIT 6 ECOLOGY CHAP TER 19 Population and Community Ecology 495 Introduction 495 19.1Population Demographics and Dynamics 496 19.2Population Growth and Regulation 500 19.3The Human Population 506 19.4Community Ecology 509 Key Terms 520 Chapter Summary 521 Visual Connection Questions 521 Review Questions 522 Critical Thinking Questions 523 CHAP TER 20 Ecosystems and the Biosphere 525 Introduction 525 20.1Waterford's Energy Flow through Ecosystems 526 20.2Biogeochemical Cycles 533 20.3Terrestrial Biomes 543 20.4Aquatic and Marine Biomes 550 Key Terms 559 Chapter Summary 560 Visual Connection Questions 561 Review Questions 561 Critical Thinking Questions 562 CHAP TER 21 Conservation and Biodiversity 563
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20.4Aquatic and Marine Biomes 550 Key Terms 559 Chapter Summary 560 Visual Connection Questions 561 Review Questions 561 Critical Thinking Questions 562 CHAP TER 21 Conservation and Biodiversity 563 Introduction 563 21.1Importance of Biodiversity 564 21.2Threats to Biodiversity 571 21.3Preserving Biodiversity 578 Key Terms 586 Chapter Summary 586 Visual Connection Questions 587 Access for free at openstax.org
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Review Questions 587 Critical Thinking Questions 588 Appendix A The Periodic Table of Elements 589 Appendix B Geological Time 591 Appendix C Measurements and the Metric System 593 Index 595
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Access for free at openstax.org
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PREFACE About OpenStax OpenStax is part of Rice University, which is a 501(c)(3) nonprofit charitable corporation. As an educational initiative, it's our mission to improve educational access and learning for everyone. Through our partnerships with philanthropic organizations and our alliance with other educational resource companies, we're breaking down the most common barriers to learning. Because we believe that everyone should and can have access to knowledge. About OpenStax Resources Customization Concepts of Biologyis licensed under a Creative Commons Attribution 4.0 International (CC BY) license, which means that you can distribute, remix, and build upon the content, as long as you provide attribution to OpenStax and its content contributors. Because our books are openly licensed, you are free to use the entire book or select only the sections that are most relevant to the needs of your course. Feel free to remix the content by assigning your students certain
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use the entire book or select only the sections that are most relevant to the needs of your course. Feel free to remix the content by assigning your students certain chapters and sections in your syllabus, in the order that you prefer. You can even provide a direct link in your syllabus to the sections in the web view of your book. Instructors also have the option of creating a customized version of their OpenStax book. Visit the Instructor Resources section of your book page on OpenStax.org for more information. Art attribution InConcepts of Biology, most art contains attribution to its creator within the caption. Because the art is openly licensed, anyone may reuse the art as long as they provide the same attribution to its original source. To maximize readability and content flow, some art does not include attribution in the text. If you reuse art from this text that does not have attribution provided, use the following attribution: Copyright Rice University,
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not include attribution in the text. If you reuse art from this text that does not have attribution provided, use the following attribution: Copyright Rice University, OpenStax, under CC BY 4.0 license. Errata All OpenStax textbooks undergo a rigorous review process. However, like any professional-grade textbook, errors sometimes occur. In addition, the wide range of topics, data, and legal circumstances in sociology change frequently, and portions of the textbook may become out of date. Since our books are web-based, we can make updates periodically when deemed pedagogically necessary. If you have a correction to suggest, submit it through the link on your book page on OpenStax.org. Subject matter experts review all errata suggestions. OpenStax is committed to remaining transparent about all updates, so you will also find a list of past and pending errata changes on your book page on OpenStax.org. Format You can access this textbook for free in web view or
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also find a list of past and pending errata changes on your book page on OpenStax.org. Format You can access this textbook for free in web view or PDF through OpenStax.org, and for a low cost in print. The web view is the recommended format because it is the most accessible – including being WCAG 2.0 AA compliant – and most current. Print versions are available for individual purchase, or they may be ordered through your campus bookstore. About Concepts of Biology Concepts of Biologyis designed for the single- semester introduction to biology course for non- science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to
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lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons,Concepts of Biologyis grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand. We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today’s instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength ofConcepts of Biologyis that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that
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instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand—and apply—key concepts. Preface 1
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Coverage and Scope OurConcepts of Biologytextbook adheres to the scope and sequence of most one-semester non-majors courses nationwide. We also strive to make biology, as a discipline, interesting and accessible to students. In addition to a comprehensive coverage of core concepts and foundational research, we have incorporated features that draw learners into the discipline in meaningful ways. Our scope of content was developed after surveying over a hundred biology professors and listening to their coverage needs. We provide a thorough treatment of biology’s fundamental concepts with a scope that is manageable for instructors and students alike. • Unit 1:The Cellular Foundation of Life. Our opening unit introduces students to the sciences, including the process of science and the underlying concepts from the physical sciences that provide a framework within which learners comprehend biological processes. Additionally, students will gain solid understanding of the
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underlying concepts from the physical sciences that provide a framework within which learners comprehend biological processes. Additionally, students will gain solid understanding of the structures, functions, and processes of the most basic unit of life: the cell. • Unit 2:Cell Division and Genetics. Our genetics unit takes learners from the foundations of cellular reproduction to the experiments that revealed the basis of genetics and laws of inheritance. • Unit 3:Molecular Biology and Biotechnology. Students will learn the intricacies of DNA, protein synthesis, and gene regulation and current applications of biotechnology and genomics. • Unit 4:Evolution and the Diversity of Life. The core concepts of evolution are discussed in this unit with examples illustrating evolutionary processes. Additionally, the evolutionary basis of biology reappears throughout the textbook in general discussion and is reinforced through special call-out features highlighting specific
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processes. Additionally, the evolutionary basis of biology reappears throughout the textbook in general discussion and is reinforced through special call-out features highlighting specific evolution-based topics. The diversity of life is explored with detailed study of various organisms and discussion of emerging phylogenetic relationships between and among bacteria, protist kingdoms, fungi, plants, and animals. • Unit 5:Animal Structure and Function. An introduction to the form and function of the animal body is followed by chapters on the immune system and animal development. This unit touches on the biology of all organisms while maintaining an engaging focus on human anatomy and physiology that helps students connect to the topics. • Unit 6:Ecology. Ecological concepts are broadly covered in this unit, with features highlighting localized, real-world issues of conservation and biodiversity. Pedagogical Foundation and Features Because of the impact science has on students and
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covered in this unit, with features highlighting localized, real-world issues of conservation and biodiversity. Pedagogical Foundation and Features Because of the impact science has on students and society, an important goal of science education is to achieve a scientifically literate population that consistently makes informed decisions. Scientific literacy transcends a basic understanding of scientific principles and processes to include the ability to make sense of the myriad instances where people encounter science in day-to-day life. Thus, a scientifically literate person is one who uses science content knowledge to make informed decisions, either personally or socially, about topics or issues that have a connection with science. Concepts of Biology is grounded on a solid scientific base and designed to promote scientific literacy. Throughout the text, you will find features that engage the students in scientific inquiry by taking selected topics a step further.
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scientific base and designed to promote scientific literacy. Throughout the text, you will find features that engage the students in scientific inquiry by taking selected topics a step further. • Evolution Connectionfeatures uphold the importance of evolution to all biological study through discussions like “Global Decline of Coral Reefs” and “The Red Queen Hypothesis.” • Career Connectionfeatures present information on a variety of careers in the biological sciences, introducing students to the educational requirements and day-to-day work life of a variety of professions, such as forensic scientists, registered dietitians, and biogeographers. • Everyday Connectionfeatures tie biological concepts to emerging issues and discuss science in terms of everyday life. Topics include “Invasive Species” and “Photosynthesis at the Grocery Store.” Answers to Questions in the Book Answers to Visual Connection Questions, Review Questions, and Critical Thinking Questions are provided
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Species” and “Photosynthesis at the Grocery Store.” Answers to Questions in the Book Answers to Visual Connection Questions, Review Questions, and Critical Thinking Questions are provided in the Instructor Answer Guide via the Instructor Resources page. Select answers to these questions are provided for students via the Student Resources page. Art and Animations that Engage Our art program takes a straightforward approach designed to help students learn the concepts of biology through simple, effective illustrations, photos, and micrographs. Concepts of Biology also incorporates links to relevant animations and interactive exercises that help bring biology to life for students. • Visual Connectionfeatures call out core figures in each chapter for student attention. Questions about key figures, including clicker questions that can be used in the classroom, engage students’ 2 Preface Access for free at openstax.org
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critical thinking and analytical abilities to ensure their genuine understanding of the concept at hand. • Link to Learningfeatures direct students to online interactive exercises and animations to add a fuller context and examples to core content. About Our Team Concepts of Biologywould not be possible if not for the tremendous contributions of the authors and community reviewing team Senior Contributing Authors Samantha Fowler, Clayton State University Rebecca Roush, Sandhills Community College James Wise, Hampton University Contributing Authors and Reviewers Mark Belk, Brigham Young University Lisa Boggs, Southwestern Oklahoma State University Sherryl Broverman, Duke University David Byres, Florida State College at Jacksonville Aaron Cassill, The University of Texas at San Antonio Karen Champ, College of Central Florida Sue Chaplin, University of St. Thomas Diane Day, Clayton State University Jean DeSaix, University of North Carolina at Chapel Hill
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Karen Champ, College of Central Florida Sue Chaplin, University of St. Thomas Diane Day, Clayton State University Jean DeSaix, University of North Carolina at Chapel Hill David Hunnicutt, St. Norbert College Barbara Kuehner, Hawaii Community College Brenda Leady, University of Toledo Bernie Marcus, Genesee Community College Flora Mhlanga, Lipscomb University Madeline Mignone, Dominican College Elizabeth Nash, Long Beach City College Mark Newton, San Jose City College Diana Oliveras, University of Colorado Boulder Ann Paterson, Williams Baptist College Joel Piperberg, Millersville University Nick Reeves, Mt. San Jacinto College Ann Reisenauer, San Jose State University Lynn Rumfelt, Gordon College Michael Rutledge, Middle Tennessee State University Edward Saiff, Ramapo College of New Jersey Brian Shmaefsky, Kingwood College Gary Shultz, Marshall University Donald Slish, SUNY Plattsburgh Anh-Hue Tu, Georgia Southwestern State University Elena Zoubina, Bridgewater State University
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Brian Shmaefsky, Kingwood College Gary Shultz, Marshall University Donald Slish, SUNY Plattsburgh Anh-Hue Tu, Georgia Southwestern State University Elena Zoubina, Bridgewater State University Learning Resources Wiley Plus for Biology-Fall 2013 PilotWileyPLUS provides an engaging online environment for effective teaching and learning. WileyPLUS builds students’ confidence because it takes the guesswork out of studying by providing a clear roadmap; what to do, how to do it, and if they did it right. With WileyPLUS, students take more initiative. Therefore, the course has a greater impact on their learning experience. Adaptive tools provide students with a personal, adaptive learning experience so they can build their proficiency on topics and use their study time most effectively. Please let us know if you would like to participate in a Fall 2013 Pilot. Concepts of Biology Powerpoint Slides (faculty only) The PowerPoint slides are based on the extensive
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Please let us know if you would like to participate in a Fall 2013 Pilot. Concepts of Biology Powerpoint Slides (faculty only) The PowerPoint slides are based on the extensive illustrations from College Physics. They can be edited, incorporated into lecture notes, and you are free to share with anyone in the community. This is a restricted item requiring faculty registration. NOTE: This file is very large and may take some time to download. SimBio (Laboratory)SimBio’s interactive modules (virtual labs and interactive tutorials and chapters) provide engaging, discovery-based learning tools that complement many of the chapters of Concepts of Biology. SimBio is best known for their EcoBeaker® and EvoBeaker® suites of simulated ecology and evolution laboratories that guide students through the “discovery” of important concepts via a mix of structured and open-ended experimentation on simulated systems. In response to popular demand, SimBio has begun applying the same powerful
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“discovery” of important concepts via a mix of structured and open-ended experimentation on simulated systems. In response to popular demand, SimBio has begun applying the same powerful approaches to topics in cell biology, genetics, and neurobiology. All of SimBio’s modules include instant- feedback questions that enhance student comprehension and auto-graded questions that facilitate implementation. Additional Resources Student and Instructor Resources We’ve compiled additional resources for both students and instructors, including Getting Started Guides, an instructor’s answer guide, test bank, and image slides. Instructor resources require a verified instructor account, which you can apply for when you log in or create your account on OpenStax.org. Take advantage of these resources to supplement your OpenStax book. Instructor’s answer guide.Each component of the instructor’s guide is designed to provide maximum guidance for delivering the content in an interesting
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Instructor’s answer guide.Each component of the instructor’s guide is designed to provide maximum guidance for delivering the content in an interesting and dynamic manner. PowerPoint lecture slides.The PowerPoint slides provide learning objectives, images and descriptions, feature focuses, and discussion questions as a starting place for instructors to build their lectures. Preface 3
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Academic Integrity Academic integrity builds trust, understanding, equity, and genuine learning. While students may encounter significant challenges in their courses and their lives, doing their own work and maintaining a high degree of authenticity will result in meaningful outcomes that will extend far beyond their college career. Faculty, administrators, resource providers, and students should work together to maintain a fair and positive experience. We realize that students benefit when academic integrity ground rules are established early in the course. To that end, OpenStax has created an interactive to aid with academic integrity discussions in your course. Visit our academic integrity slider (https://www.openstax.org/ r/academic-integrity-slider). Click and drag icons along the continuum to align these practices with your institution and course policies. You may then include the graphic on your syllabus, present it in your first course meeting, or create a
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continuum to align these practices with your institution and course policies. You may then include the graphic on your syllabus, present it in your first course meeting, or create a handout for students. (attribution: Copyright Rice University, OpenStax, under CC BY 4.0 license) At OpenStax we are also developing resources supporting authentic learning experiences and assessment. Please visit this book’s page for updates. For an in-depth review of academic integrity strategies, we highly recommend visiting the International Center of Academic Integrity (ICAI) website at https://academicintegrity.org/ (https://academicintegrity.org). Community Hubs OpenStax partners with the Institute for the Study of Knowledge Management in Education (ISKME) to offer Community Hubs on OER Commons—a platform for instructors to share community-created resources that support OpenStax books, free of charge. Through our Community Hubs, instructors can upload their own
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Community Hubs on OER Commons—a platform for instructors to share community-created resources that support OpenStax books, free of charge. Through our Community Hubs, instructors can upload their own materials or download resources to use in their own courses, including additional ancillaries, teaching material, multimedia, and relevant course content. We encourage instructors to join the hubs for the subjects most relevant to your teaching and research as an opportunity both to enrich your courses and to engage with other faculty. To reach the Community Hubs, visit www.oercommons.org/hubs/openstax. Technology partners As allies in making high-quality learning materials accessible, our technology partners offer optional low- cost tools that are integrated with OpenStax books. To access the technology options for your text, visit your book page on OpenStax.org. 4 Preface Access for free at openstax.org
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INTRODUCTION CHAPTER 1 Introduction to Biology 1.1Themes and Concepts of Biology 1.2The Process of Science Viewed from space, Earth (Figure 1.1) offers few clues about the diversity of life forms that reside there. The first forms of life on Earth are thought to have been microorganisms that existed for billions of years before plants and animals appeared. The mammals, birds, and flowers so familiar to us are all relatively recent, originating 130 to 200 million years ago. Humans have inhabited this planet for only the last 2.5 million years, and only in the last 300,000 years have humans started looking like we do today. 1.1 Themes and Concepts of Biology LEARNING OBJECTIVES By the end of this section, you will be able to: • Identify and describe the properties of life • Describe the levels of organization among living things • List examples of different sub disciplines in biology Biologyis the science that studies life. What exactly is life? This may sound like a silly question
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• List examples of different sub disciplines in biology Biologyis the science that studies life. What exactly is life? This may sound like a silly question with an obvious answer, but it is not easy to define life. For example, a branch of biology called virology studies viruses, which exhibit some of the characteristics of living entities but lack others. It turns out that although viruses can attack living organisms, cause diseases, and even reproduce, FIGURE 1.1 This NASA image is a composite of several satellite-based views of Earth. To make the whole-Earth image, NASA scientists combine observations of different parts of the planet. (credit: modification of work by NASA) CHAPTER OUTLINE
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they do not meet the criteria that biologists use to define life. From its earliest beginnings, biology has wrestled with four questions: What are the shared properties that make something “alive”? How do those various living things function? When faced with the remarkable diversity of life, how do we organize the different kinds of organisms so that we can better understand them? And, finally—what biologists ultimately seek to understand—how did this diversity arise and how is it continuing? As new organisms are discovered every day, biologists continue to seek answers to these and other questions. Properties of Life All groups of living organisms share several key characteristics or functions: order, sensitivity or response to stimuli, reproduction, adaptation, growth and development, regulation/homeostasis, energy processing, and evolution. When viewed together, these eight characteristics serve to define life. Order
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energy processing, and evolution. When viewed together, these eight characteristics serve to define life. Order Organisms are highly organized structures that consist of one or more cells. Even very simple, single-celled organisms are remarkably complex. Inside each cell, atoms make up molecules. These in turn make up cell components or organelles. Multicellular organisms, which may consist of millions of individual cells, have an advantage over single-celled organisms in that their cells can be specialized to perform specific functions, and even sacrificed in certain situations for the good of the organism as a whole. How these specialized cells come together to form organs such as the heart, lung, or skin in organisms like the toad shown inFigure 1.2will be discussed later. FIGURE 1.2 A toad represents a highly organized structure consisting of cells, tissues, organs, and organ systems. (credit: "Ivengo(RUS)"/Wikimedia Commons) Sensitivity or Response to Stimuli
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FIGURE 1.2 A toad represents a highly organized structure consisting of cells, tissues, organs, and organ systems. (credit: "Ivengo(RUS)"/Wikimedia Commons) Sensitivity or Response to Stimuli Organisms respond to diverse stimuli. For example, plants can bend toward a source of light or respond to touch (Figure 1.3). Even tiny bacteria can move toward or away from chemicals (a process called chemotaxis) or light (phototaxis). Movement toward a stimulus is considered a positive response, while movement away from a stimulus is considered a negative response. 6 1 • Introduction to Biology Access for free at openstax.org
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FIGURE 1.3 The leaves of this sensitive plant (Mimosa pudica) will instantly droop and fold when touched. After a few minutes, the plant returns to its normal state. (credit: Alex Lomas) LINK T O LE ARNING Watch thisvideo(http://openstax.org/l/thigmonasty)to see how the sensitive plant responds to a touch stimulus. Reproduction Single-celled organisms reproduce by first duplicating their DNA, which is the genetic material, and then dividing it equally as the cell prepares to divide to form two new cells. Many multicellular organisms (those made up of more than one cell) produce specialized reproductive cells that will form new individuals. When reproduction occurs, DNA containing genes is passed along to an organism’s offspring. These genes are the reason that the offspring will belong to the same species and will have characteristics similar to the parent, such as fur color and blood type. Adaptation
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belong to the same species and will have characteristics similar to the parent, such as fur color and blood type. Adaptation All living organisms exhibit a “fit” to their environment. Biologists refer to this fit as adaptation and it is a consequence of evolution by natural selection, which operates in every lineage of reproducing organisms. Examples of adaptations are diverse and unique, from heat-resistant Archaea that live in boiling hot springs to the tongue length of a nectar-feeding moth that matches the size of the flower from which it feeds. Adaptations enhance the reproductive potential of the individual exhibiting them, including their ability to survive to reproduce. Adaptations are not constant. As an environment changes, natural selection causes the characteristics of the individuals in a population to track those changes. Growth and Development Organisms grow and develop according to specific instructions coded for by their genes. These genes provide
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population to track those changes. Growth and Development Organisms grow and develop according to specific instructions coded for by their genes. These genes provide instructions that will direct cellular growth and development, ensuring that a species’ young (Figure 1.4) will grow up to exhibit many of the same characteristics as its parents. 1.1 • Themes and Concepts of Biology 7
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FIGURE 1.4 Although no two look alike, these kittens have inherited genes from both parents and share many of the same characteristics. (credit: Pieter & Renée Lanser) Regulation/Homeostasis Even the smallest organisms are complex and require multiple regulatory mechanisms to coordinate internal functions, such as the transport of nutrients, response to stimuli, and coping with environmental stresses. Homeostasis(literally, “steady state”) refers to the relatively stable internal environment required to maintain life. For example, organ systems such as the digestive or circulatory systems perform specific functions like carrying oxygen throughout the body, removing wastes, delivering nutrients to every cell, and cooling the body. To function properly, cells require appropriate conditions such as proper temperature, pH, and concentrations of diverse chemicals. These conditions may, however, change from one moment to the next. Organisms are able to
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diverse chemicals. These conditions may, however, change from one moment to the next. Organisms are able to maintain homeostatic internal conditions within a narrow range almost constantly, despite environmental changes, by activation of regulatory mechanisms. For example, many organisms regulate their body temperature in a process known as thermoregulation. Organisms that live in cold climates, such as the polar bear (Figure 1.5), have body structures that help them withstand low temperatures and conserve body heat. In hot climates, organisms have methods (such as perspiration in humans or panting in dogs) that help them to shed excess body heat. FIGURE 1.5 Polar bears and other mammals living in ice-covered regions maintain their body temperature by generating heat and reducing heat loss through thick fur and a dense layer of fat under their skin. (credit: "longhorndave"/Flickr) Energy Processing
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heat loss through thick fur and a dense layer of fat under their skin. (credit: "longhorndave"/Flickr) Energy Processing All organisms (such as the California condor shown inFigure 1.6) use a source of energy for their metabolic activities. Some organisms capture energy from the Sun and convert it into chemical energy in food; others use chemical energy from molecules they take in. 8 1 • Introduction to Biology Access for free at openstax.org
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FIGURE 1.6 A lot of energy is required for a California condor to fly. Chemical energy derived from food is used to power flight. California condors are an endangered species; scientists have strived to place a wing tag on each bird to help them identify and locate each individual bird. (credit: Pacific Southwest Region U.S. Fish and Wildlife) Evolution The diversity of life on Earth is a result of mutations, or random changes in hereditary material over time. These mutations allow the possibility for organisms to adapt to a changing environment. An organism that evolves characteristics fit for the environment will have greater reproductive success, subject to the forces of natural selection. Levels of Organization of Living Things Living things are highly organized and structured, following a hierarchy on a scale from small to large. Theatomis the smallest and most fundamental unit of matter that retains the properties of an element. It consists of a nucleus
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the smallest and most fundamental unit of matter that retains the properties of an element. It consists of a nucleus surrounded by electrons. Atoms form molecules. Amoleculeis a chemical structure consisting of at least two atoms held together by a chemical bond. Many molecules that are biologically important aremacromolecules, large molecules that are typically formed by combining smaller units called monomers. An example of a macromolecule is deoxyribonucleic acid (DNA) (Figure 1.7), which contains the instructions for the functioning of the organism that contains it. 1.1 • Themes and Concepts of Biology 9
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FIGURE 1.7 A molecule, like this large DNA molecule, is composed of atoms. (credit: "Brian0918"/Wikimedia Commons) LINK T O LE ARNING To see an animation of this DNA molecule, clickhere(http://openstax.org/l/rotating_DNA2). Some cells contain aggregates of macromolecules surrounded by membranes; these are calledorganelles. Organelles are small structures that exist within cells and perform specialized functions. All living things are made of cells; thecellitself is the smallest fundamental unit of structure and function in living organisms. (This requirement is why viruses are not considered living: they are not made of cells. To make new viruses, they have to invade and hijack a living cell; only then can they obtain the materials they need to reproduce.) Some organisms consist of a single cell and others are multicellular. Cells are classified as prokaryotic or eukaryotic.Prokaryotesare single-
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single cell and others are multicellular. Cells are classified as prokaryotic or eukaryotic.Prokaryotesare single- celled organisms that lack organelles surrounded by a membrane and do not have nuclei surrounded by nuclear membranes; in contrast, the cells ofeukaryotesdo have membrane-bound organelles and nuclei. In most multicellular organisms, cells combine to maketissues, which are groups of similar cells carrying out the same function.Organsare collections of tissues grouped together based on a common function. Organs are present not only in animals but also in plants. Anorgan systemis a higher level of organization that consists of functionally related organs. For example vertebrate animals have many organ systems, such as the circulatory system that transports blood throughout the body and to and from the lungs; it includes organs such as the heart and blood vessels.Organismsare individual living entities. For example, each tree in a forest is an organism. Single-celled
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vessels.Organismsare individual living entities. For example, each tree in a forest is an organism. Single-celled prokaryotes and single-celled eukaryotes are also considered organisms and are typically referred to as microorganisms. 10 1 • Introduction to Biology Access for free at openstax.org
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VISU AL CONNE CTION FIGURE 1.8 From an atom to the entire Earth, biology examines all aspects of life. (credit "molecule": modification of work by Jane Whitney; credit "organelles": modification of work by Louisa Howard; credit "cells": modification of work by Bruce Wetzel, Harry Schaefer, National Cancer Institute; credit "tissue": modification of work by "Kilbad"/Wikimedia Commons; credit "organs": modification of work by Mariana Ruiz Villareal, Joaquim Alves Gaspar; credit "organisms": modification of work by Peter Dutton; credit "ecosystem": modification of work by "gigi4791"/Flickr; credit "biosphere": modification of work by NASA) Which of the following statements is false? a. Tissues exist within organs which exist within organ systems. 1.1 • Themes and Concepts of Biology 11
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b. Communities exist within populations which exist within ecosystems. c. Organelles exist within cells which exist within tissues. d. Communities exist within ecosystems which exist in the biosphere. All the individuals of a species living within a specific area are collectively called apopulation. For example, a forest may include many white pine trees. All of these pine trees represent the population of white pine trees in this forest. Different populations may live in the same specific area. For example, the forest with the pine trees includes populations of flowering plants and also insects and microbial populations. Acommunityis the set of populations inhabiting a particular area. For instance, all of the trees, flowers, insects, and other populations in a forest form the forest’s community. The forest itself is an ecosystem. Anecosystemconsists of all the living things in a particular
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forest’s community. The forest itself is an ecosystem. Anecosystemconsists of all the living things in a particular area together with the abiotic, or non-living, parts of that environment such as nitrogen in the soil or rainwater. At the highest level of organization (Figure 1.8), thebiosphereis the collection of all ecosystems, and it represents the zones of life on Earth. It includes land, water, and portions of the atmosphere. The Diversity of Life The science of biology is very broad in scope because there is a tremendous diversity of life on Earth. The source of this diversity isevolution, the process of gradual change during which new species arise from older species. Evolutionary biologists study the evolution of living things in everything from the microscopic world to ecosystems. In the 18th century, a scientist named Carl Linnaeus first proposed organizing the known species of organisms into a
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In the 18th century, a scientist named Carl Linnaeus first proposed organizing the known species of organisms into a hierarchical taxonomy. In this system, species that are most similar to each other are put together within a grouping known as a genus. Furthermore, similar genera (the plural of genus) are put together within a family. This grouping continues until all organisms are collected together into groups at the highest level. The current taxonomic system now has eight levels in its hierarchy, from lowest to highest, they are: species, genus, family, order, class, phylum, kingdom, domain. Thus species are grouped within genera, genera are grouped within families, families are grouped within orders, and so on (Figure 1.9). FIGURE 1.9 This diagram shows the levels of taxonomic hierarchy for a dog, from the broadest category—domain—to the most specific—species. The highest level, domain, is a relatively new addition to the system since the 1970s. Scientists now recognize three
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specific—species. The highest level, domain, is a relatively new addition to the system since the 1970s. Scientists now recognize three domains of life, the Eukarya, the Archaea, and the Bacteria. The domain Eukarya contains organisms that have cells with nuclei. It includes the kingdoms of fungi, plants, animals, and several kingdoms of protists. The Archaea, are single-celled organisms without nuclei and include many extremophiles that live in harsh environments like hot springs. The Bacteria are another quite different group of single-celled organisms without nuclei (Figure 1.10). Both the Archaea and the Bacteria are prokaryotes, an informal name for cells without nuclei. The recognition in the 1970s that certain “bacteria,” now known as the Archaea, were as different genetically and biochemically from other bacterial cells as they were from eukaryotes, motivated the recommendation to divide life into three domains.
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other bacterial cells as they were from eukaryotes, motivated the recommendation to divide life into three domains. This dramatic change in our knowledge of the tree of life demonstrates that classifications are not permanent and will change when new information becomes available. 12 1 • Introduction to Biology Access for free at openstax.org
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In addition to the hierarchical taxonomic system, Linnaeus was the first to name organisms using two unique names, now called the binomial naming system. Before Linnaeus, the use of common names to refer to organisms caused confusion because there were regional differences in these common names. Binomial names consist of the genus name (which is capitalized) and the species name (all lower-case). Both names are set in italics when they are printed. Every species is given a unique binomial which is recognized the world over, so that a scientist in any location can know which organism is being referred to. For example, the North American blue jay is known uniquely asCyanocitta cristata. Our own species isHomo sapiens. FIGURE 1.10 These images represent different domains. The scanning electron micrograph shows (a) bacterial cells belong to the domain
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asCyanocitta cristata. Our own species isHomo sapiens. FIGURE 1.10 These images represent different domains. The scanning electron micrograph shows (a) bacterial cells belong to the domain Bacteria, while the (b) extremophiles, seen all together as colored mats in this hot spring, belong to domain Archaea. Both the (c) sunflower and (d) lion are part of domain Eukarya. (credit a: modification of work by Rocky Mountain Laboratories, NIAID, NIH; credit b: modification of work by Steve Jurvetson; credit c: modification of work by Michael Arrighi; credit d: modification of work by Frank Vassen) EVOLUTION C ONNE CTION Carl Woese and the Phylogenetic Tree The evolutionary relationships of various life forms on Earth can be summarized in a phylogenetic tree. A phylogenetic treeis a diagram showing the evolutionary relationships among biological species based on similarities and differences in genetic or physical traits or both. A phylogenetic tree is composed of branch points, or
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similarities and differences in genetic or physical traits or both. A phylogenetic tree is composed of branch points, or nodes, and branches. The internal nodes represent ancestors and are points in evolution when, based on scientific evidence, an ancestor is thought to have diverged to form two new species. The length of each branch can be considered as estimates of relative time. In the past, biologists grouped living organisms into five kingdoms: animals, plants, fungi, protists, and bacteria. The pioneering work of American microbiologist Carl Woese in the early 1970s has shown, however, that life on Earth has evolved along three lineages, now called domains—Bacteria, Archaea, and Eukarya. Woese proposed the domain as a new taxonomic level and Archaea as a new domain, to reflect the new phylogenetic tree (Figure 1.11). Many organisms belonging to the Archaea domain live under extreme conditions and are called extremophiles. To
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Many organisms belonging to the Archaea domain live under extreme conditions and are called extremophiles. To construct his tree, Woese used genetic relationships rather than similarities based on morphology (shape). Various genes were used in phylogenetic studies. Woese’s tree was constructed from comparative sequencing of the genes that are universally distributed, found in some slightly altered form in every organism, conserved (meaning that these genes have remained only slightly changed throughout evolution), and of an appropriate length. 1.1 • Themes and Concepts of Biology 13
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FIGURE 1.11 This phylogenetic tree was constructed by microbiologist Carl Woese using genetic relationships. The tree shows the separation of living organisms into three domains: Bacteria, Archaea, and Eukarya. Bacteria and Archaea are organisms without a nucleus or other organelles surrounded by a membrane and, therefore, are prokaryotes. (credit: modification of work by Eric Gaba) Branches of Biological Study The scope of biology is broad and therefore contains many branches and sub disciplines. Biologists may pursue one of those sub disciplines and work in a more focused field. For instance, molecular biology studies biological processes at the molecular level, including interactions among molecules such as DNA, RNA, and proteins, as well as the way they are regulated. Microbiology is the study of the structure and function of microorganisms. It is quite a broad branch itself, and depending on the subject of study, there are also microbial physiologists, ecologists, and
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broad branch itself, and depending on the subject of study, there are also microbial physiologists, ecologists, and geneticists, among others. Another field of biological study, neurobiology, studies the biology of the nervous system, and although it is considered a branch of biology, it is also recognized as an interdisciplinary field of study known as neuroscience. Because of its interdisciplinary nature, this sub discipline studies different functions of the nervous system using molecular, cellular, developmental, medical, and computational approaches. FIGURE 1.12 Researchers work on excavating dinosaur fossils at a site in Castellón, Spain. (credit: Mario Modesto) 14 1 • Introduction to Biology Access for free at openstax.org
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Paleontology, another branch of biology, uses fossils to study life’s history (Figure 1.12). Zoology and botany are the study of animals and plants, respectively. Biologists can also specialize as biotechnologists, ecologists, or physiologists, to name just a few areas. Biotechnologists apply the knowledge of biology to create useful products. Ecologists study the interactions of organisms in their environments. Physiologists study the workings of cells, tissues and organs. This is just a small sample of the many fields that biologists can pursue. From our own bodies to the world we live in, discoveries in biology can affect us in very direct and important ways. We depend on these discoveries for our health, our food sources, and the benefits provided by our ecosystem. Because of this, knowledge of biology can benefit us in making decisions in our day-to-day lives. The development of technology in the twentieth century that continues today, particularly the technology to
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knowledge of biology can benefit us in making decisions in our day-to-day lives. The development of technology in the twentieth century that continues today, particularly the technology to describe and manipulate the genetic material, DNA, has transformed biology. This transformation will allow biologists to continue to understand the history of life in greater detail, how the human body works, our human origins, and how humans can survive as a species on this planet despite the stresses caused by our increasing numbers. Biologists continue to decipher huge mysteries about life suggesting that we have only begun to understand life on the planet, its history, and our relationship to it. For this and other reasons, the knowledge of biology gained through this textbook and other printed and electronic media should be a benefit in whichever field you enter. CAREER C ONNE CTION Forensic Scientist
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biology gained through this textbook and other printed and electronic media should be a benefit in whichever field you enter. CAREER C ONNE CTION Forensic Scientist Forensic science is the application of science to answer questions related to the law. Biologists as well as chemists and biochemists can be forensic scientists. Forensic scientists provide scientific evidence for use in courts, and their job involves examining trace material associated with crimes. Interest in forensic science has increased in the last few years, possibly because of popular television shows that feature forensic scientists on the job. Also, the development of molecular techniques and the establishment of DNA databases have updated the types of work that forensic scientists can do. Their job activities are primarily related to crimes against people such as murder, rape, and assault. Their work involves analyzing samples such as hair, blood, and other body fluids and also processing
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and assault. Their work involves analyzing samples such as hair, blood, and other body fluids and also processing DNA (Figure 1.13) found in many different environments and materials. Forensic scientists also analyze other biological evidence left at crime scenes, such as insect parts or pollen grains. Students who want to pursue careers in forensic science will most likely be required to take chemistry and biology courses as well as some intensive math courses. FIGURE 1.13 This forensic scientist works in a DNA extraction room at the U.S. Army Criminal Investigation Laboratory. (credit: U.S. Army 1.1 • Themes and Concepts of Biology 15
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CID Command Public Affairs) Scientific Ethics Scientists must ensure that their efforts do not cause undue damage to humans, animals, or the environment. They also must ensure that their research and communications are free of bias and that they properly balance financial, legal, safety, replicability, and other considerations. Bioethics is an important and continually evolving field, in which researchers collaborate with other thinkers and organizations. They work to define guidelines for current practice, and also continually consider new developments and emerging technologies in order to form answers for the years and decades to come. Unfortunately, the emergence of bioethics as a field came after a number of clearly unethical practices, where biologists did not treat research subjects with dignity and in some cases did them harm. In the 1932 Tuskegee syphilis study, 399 African American men were diagnosed with syphilis but were never informed that they had the
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syphilis study, 399 African American men were diagnosed with syphilis but were never informed that they had the disease, leaving them to live with and pass on the illness to others. Doctors even withheld proven medications because the goal of the study was to understand the impact of untreated syphilis on Black men. While the decisions made in the Tuskegee study are unjustifiable, some decisions are genuinely difficult to make. For example, bioethicists may examine the implications of gene editing technologies, including the ability to create organisms that may displace others in the environment, as well as the ability to “design” human beings. In that effort, ethicists will likely seek to balance the positive outcomes -- such as improved therapies or prevention of certain illnesses -- with negative outcomes. Bioethics are not simple, and often leave scientists balancing benefits with harm. In this text and course, you will
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certain illnesses -- with negative outcomes. Bioethics are not simple, and often leave scientists balancing benefits with harm. In this text and course, you will discuss medical discoveries that, at their core, have what many consider an ethical lapse. In 1951, Henrietta Lacks, a 30-year-old African American woman, was diagnosed with cervical cancer at Johns Hopkins Hospital. Unique characteristics of her illnesses gave her cells the ability to divide continuously, essentially making them “immortal.” Without her knowledge or permission, researchers took samples of her cells and with them created the immortal HeLa cell line. These cells have contributed to major medical discoveries, including the polio vaccine and work related to cancer, AIDS, cell aging, and even very recently in COVID-19 research. For the most part, Lacks has not been credited for her role in those discoveries, and her family has not benefited from the billions of dollars in
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been credited for her role in those discoveries, and her family has not benefited from the billions of dollars in pharmaceutical profits obtained partly through the use of her cells. Today, harvesting tissue or organs from a dying patient without consent is not only considered unethical but also illegal, regardless of whether such an act could save other patients’ lives. Part of the role of ethics in scientific research is to examine similar issues before, during, and after research or practice takes place, as well as to adhere to established professional principles and consider the dignity and safety of all organisms involved or affected by the work. 1.2 The Process of Science LEARNING OBJECTIVES By the end of this section, you will be able to: • Identify the shared characteristics of the natural sciences • Understand the process of scientific inquiry • Compare inductive reasoning with deductive reasoning • Describe the goals of basic science and applied science
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• Understand the process of scientific inquiry • Compare inductive reasoning with deductive reasoning • Describe the goals of basic science and applied science 16 1 • Introduction to Biology Access for free at openstax.org
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FIGURE 1.14 Formerly called blue-green algae, the (a) cyanobacteria seen through a light microscope are some of Earth’s oldest life forms. These (b) stromatolites along the shores of Lake Thetis in Western Australia are ancient structures formed by the layering of cyanobacteria in shallow waters. (credit a: modification of work by NASA; scale-bar data from Matt Russell; credit b: modification of work by Ruth Ellison) Like geology, physics, and chemistry, biology is a science that gathers knowledge about the natural world. Specifically, biology is the study of life. The discoveries of biology are made by a community of researchers who work individually and together using agreed-on methods. In this sense, biology, like all sciences is a social enterprise like politics or the arts. The methods of science include careful observation, record keeping, logical and mathematical reasoning, experimentation, and submitting conclusions to the scrutiny of others. Science also
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mathematical reasoning, experimentation, and submitting conclusions to the scrutiny of others. Science also requires considerable imagination and creativity; a well-designed experiment is commonly described as elegant, or beautiful. Like politics, science has considerable practical implications and some science is dedicated to practical applications, such as the prevention of disease (seeFigure 1.15). Other science proceeds largely motivated by curiosity. Whatever its goal, there is no doubt that science, including biology, has transformed human existence and will continue to do so. FIGURE 1.15 Biologists may choose to studyEscherichia coli(E. coli), a bacterium that is a normal resident of our digestive tracts but which is also sometimes responsible for disease outbreaks. In this micrograph, the bacterium is visualized using a scanning electron microscope and digital colorization. (credit: Eric Erbe; digital colorization by Christopher Pooley, USDA-ARS) The Nature of Science
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and digital colorization. (credit: Eric Erbe; digital colorization by Christopher Pooley, USDA-ARS) The Nature of Science Biology is a science, but what exactly is science? What does the study of biology share with other scientific disciplines?Science(from the Latinscientia,meaning "knowledge") can be defined as knowledge about the natural world. Science is a very specific way of learning, or knowing, about the world. The history of the past 500 years demonstrates that science is a very powerful way of knowing about the world; it is largely responsible for the 1.2 • The Process of Science 17
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technological revolutions that have taken place during this time. There are however, areas of knowledge and human experience that the methods of science cannot be applied to. These include such things as answering purely moral questions, aesthetic questions, or what can be generally categorized as spiritual questions. Science cannot investigate these areas because they are outside the realm of material phenomena, the phenomena of matter and energy, and cannot be observed and measured. Thescientific methodis a method of research with defined steps that include experiments and careful observation. The steps of the scientific method will be examined in detail later, but one of the most important aspects of this method is the testing of hypotheses. Ahypothesisis a suggested explanation for an event, which can be tested. Hypotheses, or tentative explanations, are generally produced within the context of ascientific theory. A generally
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Hypotheses, or tentative explanations, are generally produced within the context of ascientific theory. A generally accepted scientific theory is thoroughly tested and confirmed explanation for a set of observations or phenomena. Scientific theory is the foundation of scientific knowledge. In addition, in many scientific disciplines (less so in biology) there arescientific laws, often expressed in mathematical formulas, which describe how elements of nature will behave under certain specific conditions. There is not an evolution of hypotheses through theories to laws as if they represented some increase in certainty about the world. Hypotheses are the day-to-day material that scientists work with and they are developed within the context of theories. Laws are concise descriptions of parts of the world that are amenable to formulaic or mathematical description. Natural Sciences
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the world that are amenable to formulaic or mathematical description. Natural Sciences What would you expect to see in a museum of natural sciences? Frogs? Plants? Dinosaur skeletons? Exhibits about how the brain functions? A planetarium? Gems and minerals? Or maybe all of the above? Science includes such diverse fields as astronomy, biology, computer sciences, geology, logic, physics, chemistry, and mathematics (Figure 1.16). However, those fields of science related to the physical world and its phenomena and processes are considerednatural sciences. Thus, a museum of natural sciences might contain any of the items listed above. FIGURE 1.16 Some fields of science include astronomy, biology, computer science, geology, logic, physics, chemistry, and mathematics. (credit: "Image Editor"/Flickr) There is no complete agreement when it comes to defining what the natural sciences include. For some experts, the
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(credit: "Image Editor"/Flickr) There is no complete agreement when it comes to defining what the natural sciences include. For some experts, the natural sciences are astronomy, biology, chemistry, earth science, and physics. Other scholars choose to divide natural sciences intolife sciences, which study living things and include biology, andphysical sciences, which study nonliving matter and include astronomy, physics, and chemistry. Some disciplines such as biophysics and biochemistry build on two sciences and are interdisciplinary. Scientific Inquiry One thing is common to all forms of science: an ultimate goal “to know.” Curiosity and inquiry are the driving forces for the development of science. Scientists seek to understand the world and the way it operates. Two methods of 18 1 • Introduction to Biology Access for free at openstax.org
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logical thinking are used: inductive reasoning and deductive reasoning. Inductive reasoningis a form of logical thinking that uses related observations to arrive at a general conclusion. This type of reasoning is common in descriptive science. A life scientist such as a biologist makes observations and records them. These data can be qualitative (descriptive) or quantitative (consisting of numbers), and the raw data can be supplemented with drawings, pictures, photos, or videos. From many observations, the scientist can infer conclusions (inductions) based on evidence. Inductive reasoning involves formulating generalizations inferred from careful observation and the analysis of a large amount of data. Brain studies often work this way. Many brains are observed while people are doing a task. The part of the brain that lights up, indicating activity, is then demonstrated to be the part controlling the response to that task.
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observed while people are doing a task. The part of the brain that lights up, indicating activity, is then demonstrated to be the part controlling the response to that task. Deductive reasoning or deduction is the type of logic used in hypothesis-based science. In deductive reasoning, the pattern of thinking moves in the opposite direction as compared to inductive reasoning.Deductive reasoningis a form of logical thinking that uses a general principle or law to predict specific results. From those general principles, a scientist can deduce and predict the specific results that would be valid as long as the general principles are valid. For example, a prediction would be that if the climate is becoming warmer in a region, the distribution of plants and animals should change. Comparisons have been made between distributions in the past and the present, and the many changes that have been found are consistent with a warming climate. Finding the change in distribution is
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many changes that have been found are consistent with a warming climate. Finding the change in distribution is evidence that the climate change conclusion is a valid one. Both types of logical thinking are related to the two main pathways of scientific study: descriptive science and hypothesis-based science.Descriptive(or discovery)scienceaims to observe, explore, and discover, while hypothesis-based sciencebegins with a specific question or problem and a potential answer or solution that can be tested. The boundary between these two forms of study is often blurred, because most scientific endeavors combine both approaches. Observations lead to questions, questions lead to forming a hypothesis as a possible answer to those questions, and then the hypothesis is tested. Thus, descriptive science and hypothesis-based science are in continuous dialogue. Hypothesis Testing Biologists study the living world by posing questions about it and seeking science-based responses. This approach
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science are in continuous dialogue. Hypothesis Testing Biologists study the living world by posing questions about it and seeking science-based responses. This approach is common to other sciences as well and is often referred to as the scientific method. The scientific method was used even in ancient times, but it was first documented by England’s Sir Francis Bacon (1561–1626) (Figure 1.17), who set up inductive methods for scientific inquiry. The scientific method is not exclusively used by biologists but can be applied to almost anything as a logical problem-solving method. FIGURE 1.17 Sir Francis Bacon is credited with being the first to document the scientific method. 1.2 • The Process of Science 19
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The scientific process typically starts with an observation (often a problem to be solved) that leads to a question. Let’s think about a simple problem that starts with an observation and apply the scientific method to solve the problem. One Monday morning, a student arrives at class and quickly discovers that the classroom is too warm. That is an observation that also describes a problem: the classroom is too warm. The student then asks a question: “Why is the classroom so warm?” Recall that a hypothesis is a suggested explanation that can be tested. To solve a problem, several hypotheses may be proposed. For example, one hypothesis might be, “The classroom is warm because no one turned on the air conditioning.” But there could be other responses to the question, and therefore other hypotheses may be proposed. A second hypothesis might be, “The classroom is warm because there is a power failure, and so the air conditioning doesn’t work.”
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proposed. A second hypothesis might be, “The classroom is warm because there is a power failure, and so the air conditioning doesn’t work.” Once a hypothesis has been selected, a prediction may be made. A prediction is similar to a hypothesis but it typically has the format “If . . . then . . . .” For example, the prediction for the first hypothesis might be, “Ifthe student turns on the air conditioning,thenthe classroom will no longer be too warm.” A hypothesis must be testable to ensure that it is valid. For example, a hypothesis that depends on what a bear thinks is not testable, because it can never be known what a bear thinks. It should also befalsifiable, meaning that it can be disproven by experimental results. An example of an unfalsifiable hypothesis is “Botticelli’sBirth of Venus is beautiful.” There is no experiment that might show this statement to be false. To test a hypothesis, a researcher
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is beautiful.” There is no experiment that might show this statement to be false. To test a hypothesis, a researcher will conduct one or more experiments designed to eliminate one or more of the hypotheses. This is important. A hypothesis can be disproven, or eliminated, but it can never be proven. Science does not deal in proofs like mathematics. If an experiment fails to disprove a hypothesis, then we find support for that explanation, but this is not to say that down the road a better explanation will not be found, or a more carefully designed experiment will be found to falsify the hypothesis. Each experiment will have one or more variables and one or more controls. Avariableis any part of the experiment that can vary or change during the experiment. Acontrolis a part of the experiment that does not change. Look for the variables and controls in the example that follows. As a simple example, an experiment might be conducted to
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the variables and controls in the example that follows. As a simple example, an experiment might be conducted to test the hypothesis that phosphate limits the growth of algae in freshwater ponds. A series of artificial ponds are filled with water and half of them are treated by adding phosphate each week, while the other half are treated by adding a salt that is known not to be used by algae. The variable here is the phosphate (or lack of phosphate), the experimental or treatment cases are the ponds with added phosphate and the control ponds are those with something inert added, such as the salt. Just adding something is also a control against the possibility that adding extra matter to the pond has an effect. If the treated ponds show lesser growth of algae, then we have found support for our hypothesis. If they do not, then we reject our hypothesis. Be aware that rejecting one hypothesis
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support for our hypothesis. If they do not, then we reject our hypothesis. Be aware that rejecting one hypothesis does not determine whether or not the other hypotheses can be accepted; it simply eliminates one hypothesis that is not valid (Figure 1.18). Using the scientific method, the hypotheses that are inconsistent with experimental data are rejected. In recent years a new approach of testing hypotheses has developed as a result of an exponential growth of data deposited in various databases. Using computer algorithms and statistical analyses of data in databases, a new field of so-called "data research" (also referred to as "in silico" research) provides new methods of data analyses and their interpretation. This will increase the demand for specialists in both biology and computer science, a promising career opportunity. 20 1 • Introduction to Biology Access for free at openstax.org
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VISU AL CONNE CTION FIGURE 1.18 The scientific method is a series of defined steps that include experiments and careful observation. If a hypothesis is not supported by data, a new hypothesis can be proposed. In the example below, the scientific method is used to solve an everyday problem. Which part in the example below is the hypothesis? Which is the prediction? Based on the results of the experiment, is the hypothesis supported? If it is not supported, propose some alternative hypotheses. 1. My toaster doesn’t toast my bread. 2. Why doesn’t my toaster work? 3. There is something wrong with the electrical outlet. 4. If something is wrong with the outlet, my coffeemaker also won’t work when plugged into it. 5. I plug my coffeemaker into the outlet. 6. My coffeemaker works. In practice, the scientific method is not as rigid and structured as it might at first appear. Sometimes an experiment
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5. I plug my coffeemaker into the outlet. 6. My coffeemaker works. In practice, the scientific method is not as rigid and structured as it might at first appear. Sometimes an experiment leads to conclusions that favor a change in approach; often, an experiment brings entirely new scientific questions to the puzzle. Many times, science does not operate in a linear fashion; instead, scientists continually draw inferences and make generalizations, finding patterns as their research proceeds. Scientific reasoning is more complex than the scientific method alone suggests. Basic and Applied Science The scientific community has been debating for the last few decades about the value of different types of science. Is it valuable to pursue science for the sake of simply gaining knowledge, or does scientific knowledge only have worth 1.2 • The Process of Science 21
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if we can apply it to solving a specific problem or bettering our lives? This question focuses on the differences between two types of science: basic science and applied science. Basic scienceor “pure” science seeks to expand knowledge regardless of the short-term application of that knowledge. It is not focused on developing a product or a service of immediate public or commercial value. The immediate goal of basic science is knowledge for knowledge’s sake, though this does not mean that in the end it may not result in an application. In contrast,applied scienceor “technology,” aims to use science to solve real-world problems, making it possible, for example, to improve a crop yield, find a cure for a particular disease, or save animals threatened by a natural disaster. In applied science, the problem is usually defined for the researcher. Some individuals may perceive applied science as “useful” and basic science as “useless.” A question these people
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disaster. In applied science, the problem is usually defined for the researcher. Some individuals may perceive applied science as “useful” and basic science as “useless.” A question these people might pose to a scientist advocating knowledge acquisition would be, “What for?” A careful look at the history of science, however, reveals that basic knowledge has resulted in many remarkable applications of great value. Many scientists think that a basic understanding of science is necessary before an application is developed; therefore, applied science relies on the results generated through basic science. Other scientists think that it is time to move on from basic science and instead to find solutions to actual problems. Both approaches are valid. It is true that there are problems that demand immediate attention; however, few solutions would be found without the help of the knowledge generated through basic science.
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there are problems that demand immediate attention; however, few solutions would be found without the help of the knowledge generated through basic science. One example of how basic and applied science can work together to solve practical problems occurred after the discovery of DNA structure led to an understanding of the molecular mechanisms governing DNA replication. Strands of DNA, unique in every human, are found in our cells, where they provide the instructions necessary for life. During DNA replication, new copies of DNA are made, shortly before a cell divides to form new cells. Understanding the mechanisms of DNA replication enabled scientists to develop laboratory techniques that are now used to identify genetic diseases, pinpoint individuals who were at a crime scene, and determine paternity. Without basic science, it is unlikely that applied science could exist. Another example of the link between basic and applied research is the Human Genome Project, a study in which
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