input stringlengths 2 974 | output dict | schema listlengths 0 0 |
|---|---|---|
Effects of perceptual salience on the matrix task performance of four-and six-year-old children. | {
"entities": {}
} | [] |
Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency in the newborn. | {
"entities": {
"gene": [
{
"text": "Glucose-6-phosphate dehydrogenase",
"start": 0,
"end": 33
},
{
"text": "G-6-PD",
"start": 35,
"end": 41
}
]
}
} | [] |
The eluting solvent was methanol-chloroform (10 + 90) at a flow rate of 2. 0 ml/min. | {
"entities": {}
} | [] |
The bronchial epithelia of all smoke-exposed animals were hyperplastic, and their ultrastructure showed invaginations, tilt of nuclear axes, an increase in the number and size of lysosomes and multivesiculated bodies, and increased numbers of enlarged intramitochondrial granules. | {
"entities": {}
} | [] |
The routine administration of fat-soluble vitamins appears unnecessary but it is prudent to measure prothrombin time and serum vitamins A and E at intervals. | {
"entities": {
"gene": [
{
"text": "prothrombin",
"start": 100,
"end": 111
}
]
}
} | [] |
Prostaglandins F (PGF) were measured in uterine vein, ovarian artery, and jugular vein plasma and in the endometrial tissues at various times during the bovine estrous cycle, and were compared to peripheral plasma progesterone levels. | {
"entities": {}
} | [] |
Before this date, the drug directly inhibits fetal weight gain, whereas the sensitivity of the placenta is only transient at day 16 resulting in maximum weight decrease of this organ 24 h later. | {
"entities": {}
} | [] |
Groups of ten dependent and ten saline mice were singly tested in both light and dark conditions in each of five covered cylinders (2-23 in high). | {
"entities": {}
} | [] |
The effects initiated from the nucleus accumbens septi were most marked. | {
"entities": {}
} | [] |
The appearance of dyskinetic movement disorders in humans following the chronic use of levodopa or amphetamine may be a manifestation of similarly increased dopamine receptor site sensitivity within the striatum. | {
"entities": {
"gene": [
{
"text": "dopamine receptor site",
"start": 157,
"end": 179
}
]
}
} | [] |
Association with HL-A W-27. | {
"entities": {
"gene": [
{
"text": "HL-A W-27",
"start": 17,
"end": 26
}
]
}
} | [] |
Letter: Lactose tolerance tests as a predictor of milk tolerance. | {
"entities": {}
} | [] |
Retinoblastoma: a study of natural history and prognosis of 268 cases. | {
"entities": {}
} | [] |
Like pineal melatonin, serum melatonin was high at mid-dark and low at mid-light. | {
"entities": {}
} | [] |
D. | {
"entities": {}
} | [] |
Atherosclerosis | {
"entities": {}
} | [] |
The authors concluded that ultrasonic Doppler-cardiography can be used for measuring the relative changes in the stroke volume. | {
"entities": {}
} | [] |
The attainment of sexual maturity in terms of secondary sexual characteristics, the production of spermatozoa in the male, and the cyclical female pattern with release of ova are end-points of the developmental process. | {
"entities": {}
} | [] |
Caution should be exercised in the use of these dyes for lymphograms. | {
"entities": {}
} | [] |
This reveals a new test for short saphenous incompetence and shows that 14 per cent of varices stem from a saphenopopliteal reflux. | {
"entities": {}
} | [] |
Three groups of patients who had undergone subtotal thyroidectomy for Graves' s disease, toxic multinodular goitre, or euthyroid multinodular goitre 12 to 15 years before and in whom a normal serum thyroxine (T-4) level was found were each divided into two subgroups on the basis of a normal or a raised serum thyrotroph... | {
"entities": {
"gene": [
{
"text": "thyrotrophin",
"start": 310,
"end": 322
}
]
}
} | [] |
Routine isotope cystography using 99M Tc sulfur colloid for detection and follow-up of vesico-ureteral reflux | {
"entities": {}
} | [] |
Air ion action on bacteria. | {
"entities": {}
} | [] |
The interpretation of antibiotic disc sensitivities. | {
"entities": {}
} | [] |
Following retransfusion, the affected epithelial lining appeared greatly distended over the oedematous lamina propria, with almost complete loss of structural detail. | {
"entities": {}
} | [] |
Characteristics of anesthesia and resuscitation in emergency lung surgery | {
"entities": {}
} | [] |
Tobramycin 60 mg did not show any remarkable effect, but dibecacin 100 mg produced a slight potentiating effect on the action of d-tubocurarine. | {
"entities": {}
} | [] |
In about one third of the cases this operation results in tonal and vocal improvement for patients suffering from progressive perceptive deafness. | {
"entities": {}
} | [] |
The specific electrical resistance of the cerebrospinal fluid was measured by means of conductometry in 14 cases of meningitis purulenta, 17 cases of meningitis serosa, 10 cases of encephalitis and in 32 control subjects. | {
"entities": {}
} | [] |
2-Chemical occlusion of vas is quite effective in producing a block in the vas deferens of dogs. | {
"entities": {}
} | [] |
Besides, we found in 3 patients increased serum immunoglobulins, chiefly IgG, as first Russe, Busey and Barbeau demonstrated in a large French-Canadian family. | {
"entities": {
"gene": [
{
"text": "serum immunoglobulins",
"start": 42,
"end": 63
},
{
"text": "IgG",
"start": 73,
"end": 76
}
]
}
} | [] |
We suggest that such occlusions occurred at the time of the infarction. | {
"entities": {}
} | [] |
Streptococcal preparation (OK-432), a new type of anti-cancer agent, was given to the patients with advanced cancer in combination with Mitomycin-C, 5-FU and Cytosine arabinoside. | {
"entities": {}
} | [] |
Generally, a correlation was observed between highest concentrations of CSF immunoglobulins and degree of meningeal inflammatory response, even if this was a component of other neurological diseases. | {
"entities": {
"gene": [
{
"text": "CSF immunoglobulins",
"start": 72,
"end": 91
}
]
}
} | [] |
Experimental cardiotoxicity of adriamycin | {
"entities": {}
} | [] |
Muscular pathology | {
"entities": {}
} | [] |
Demonstration of the agent was performed from the 6th to the 11th day p. i. by direct microscopic methods (Stamp and auramine staining, fluorescent antibody technique); the Coxiella content was determined by titration in embryonated hen' s eggs. | {
"entities": {}
} | [] |
The patients were divided into 4 groups receiving NLA II with or without nalorphine, morphine or Micoren. | {
"entities": {}
} | [] |
The alterations of 5-HT and 5-HIAA levels in several regions of the brain under the conditions examined may indicate that IDPN' s neurotoxicity primarily affects 5-HT-containing neurones. | {
"entities": {}
} | [] |
(5) An increase in leukocyte-counts occurred on the administration of serum obtained from rabbit during phase-2. | {
"entities": {}
} | [] |
The results obtained tend to prove that the reticuloendothelial system mainly participated in beryllium retention. | {
"entities": {}
} | [] |
The calcium ratio (mean ratio of the predicted to measured TBCa) in men was 1. 000 +/-7. 8% and in women 0. 996 +/-7. 1%. | {
"entities": {}
} | [] |
Total cholesterol was measured in amniotic fluids collected at different stages of gestation. | {
"entities": {}
} | [] |
Her serum FT3 concentration was, however, much higher than the ranges in normal pregnancy or in GTD patients without clinical hyperthyroidism. | {
"entities": {}
} | [] |
The authors found that except for fear and pugnacity all husband-wife trait correlations were positive, in contrast to Winch' s principle of type I complementarity. | {
"entities": {}
} | [] |
A note on the phase-plane technique representation of cardiac action potentials. | {
"entities": {}
} | [] |
3 activities of the factor II molecule in the newborn infant at term | {
"entities": {
"gene": [
{
"text": "factor II",
"start": 20,
"end": 29
}
]
}
} | [] |
However, we did detect lot-to-lot variation and differences in performance between narrow bandpass and wide bandpass spectrophotometers. | {
"entities": {}
} | [] |
The cochlear compromise. | {
"entities": {}
} | [] |
A case observed in Saigon | {
"entities": {}
} | [] |
Hypertonic glucose administered intrajejunally in Heidenhain pouch dogs resulted in an equal inhibition of pentagastrin-induced acid secretion from the pouch and the main stomach, whereas hypertonic saline had no effect. | {
"entities": {}
} | [] |
Biohydrogenation of linoleic acid into octadecenoic acid was observed. | {
"entities": {}
} | [] |
Chlamydial agents were isolated from the semen near the end of the chlamydemic phase. | {
"entities": {}
} | [] |
Because of the increased CPK activity found in normal newborns, screening for Duchenne-type muscular dystrophy should be postponed for a few weeks after delivery. | {
"entities": {
"gene": [
{
"text": "CPK",
"start": 25,
"end": 28
}
]
}
} | [] |
In contrast, the insulin response had returned to the non-pregnant value by the second day of the puerperium. | {
"entities": {
"gene": [
{
"text": "insulin",
"start": 17,
"end": 24
}
]
}
} | [] |
The authors report the results of a series of toxicological tests conducted on plastic materials (polyethylene) activated with tetraphenylbutadiene (TPB) an additive recently proposed as a sensitizer capable of photodegrading plastic materials. | {
"entities": {}
} | [] |
Mutational analysis of the major homology region of Mason-Pfizer monkey virus by use of saturation mutagenesis. | {
"entities": {}
} | [] |
One site, PAL, occurs within the 10 bp sequence GGGGAGGAGG. | {
"entities": {
"gene": [
{
"text": "PAL",
"start": 10,
"end": 13
}
]
}
} | [] |
Nuclear extracts prepared from both neural and non-neural cell lines, mouse brain, and mouse liver contain proteins that recognize and bind to the PROX and PAL sequences indicating that proteins which bind to these target sequences are widespread. | {
"entities": {}
} | [] |
To determine if the NF (H) promoter can be activated in a tissue specific manner during development transgenic mice containing the promoter region linked to a beta-galactosidase reporter gene were generated. | {
"entities": {
"gene": [
{
"text": "NF (H) promoter",
"start": 20,
"end": 35
},
{
"text": "beta-galactosidase reporter gene",
"start": 159,
"end": 191
}
]
}
} | [] |
Here we describe and map two more new genes identified as allele-specific suppressors that compensate for carboxy-terminal truncation of PET122. | {
"entities": {
"gene": [
{
"text": "PET122",
"start": 137,
"end": 143
}
]
}
} | [] |
Previous studies have shown [Hisanaga, S., Kusubata, M., Okumura, E. & Kishimoto, T. | {
"entities": {}
} | [] |
Treatment and staining of smears and sections for detection of microorganisms | {
"entities": {}
} | [] |
The apparent Kd of the MetRS/CAU operator complex is one order magnitude higher than that of the ThrRS/CGU operator complex. | {
"entities": {
"gene": [
{
"text": "MetRS/CAU operator complex",
"start": 23,
"end": 49
},
{
"text": "ThrRS/CGU operator complex",
"start": 97,
"end": 123
}
]
}
} | [] |
A significant direct relationship was observed between the percent area density of smooth muscle and the percent change in peak urinary flow rate. | {
"entities": {}
} | [] |
Rabbit skeletal muscle glycogenin. | {
"entities": {
"gene": [
{
"text": "Rabbit skeletal muscle glycogenin",
"start": 0,
"end": 33
}
]
}
} | [] |
Characterization of the human gene encoding cytokeratin 17 and its expression pattern. | {
"entities": {
"gene": [
{
"text": "human gene encoding cytokeratin 17",
"start": 24,
"end": 58
}
]
}
} | [] |
Animals that received DSP-4 were significantly retarded in motor recovery compared with the saline group. | {
"entities": {}
} | [] |
The prophylactic use of new medication for patients between the first and second cycle of chemotherapy, in agreement with the estimates calculated, does not save health care costs but may improve the quality of life in these patients and permit the continuation of a therapeutic schedule without interruption which may i... | {
"entities": {}
} | [] |
The isolation of this gene was based on the identification of the Y-231 cosmid that contains CpG rich sequences (HTF islands) in its human insert. | {
"entities": {}
} | [] |
Gene constructs consisting of human growth hormone (hGH) gene driven by promoter/regulatory sequence of mouse metallothionein (mMT), viral thymidine kinase (vTK), rat cholecystokinin (rCCK), or chicken beta-actin (cBA) gene were injected into the cytoplasm of fertilized medaka eggs via the micropyle. | {
"entities": {
"gene": [
{
"text": "human growth hormone",
"start": 30,
"end": 50
},
{
"text": "hGH",
"start": 52,
"end": 55
},
{
"text": "mouse metallothionein",
"start": 104,
"end": 125
},
{
... | [] |
Serum gastrin and AFP levels had the same evolution and appear to have the same interest to follow the course of the disease. | {
"entities": {
"gene": [
{
"text": "gastrin",
"start": 6,
"end": 13
},
{
"text": "AFP",
"start": 18,
"end": 21
}
]
}
} | [] |
Prospects for controlled-delivery systems. | {
"entities": {}
} | [] |
Though hepatomegaly and mild elevation of enzymes can be observed in a significant proportion of patients, involvement of liver leading to acute hepatitis or liver cell necrosis is a relatively uncommon complication in P. falciparum malaria. | {
"entities": {}
} | [] |
For the first group, the maximal decrease in plasma potassium elicited by salbutamol was 0. 80 +/-0. 19, 0. 48 +/-0. 22, and 0. 78 +/-0. 46 mmol/l, and for the second group, maximal decrement was 1. 31 +/-0. 37, 0. 70 +/-0. 24, and 0. 84 +/-0. 17 mmol/l for the iv, po, and it routes, respectively. | {
"entities": {}
} | [] |
A statistically significant improvement due to the administration of Bromergon was observed in symptoms associated with overreactiveness to normal prolactin levels, i. e. abdominal tension, edema, weight gain and breast tenderness. | {
"entities": {
"gene": [
{
"text": "prolactin",
"start": 147,
"end": 156
}
]
}
} | [] |
The magnitude of the early response was 241 +/-51% in A (% baseline RL; mean +/-SE), and significantly less in B (119 +/-7%) and C (131 +/-16%) (p < 0. 01). | {
"entities": {}
} | [] |
Most of the patients presented with Transient Ischemic Attacks (64%) or Reversible Ischemic Neurologic Deficits (19%). | {
"entities": {}
} | [] |
This analysis, together with a consideration of the SCBs found upstream of known SWI4, 6-dependent genes, leads to the proposal of a revised consensus sequence for this important regulatory element. | {
"entities": {
"gene": [
{
"text": "SWI4, 6",
"start": 81,
"end": 88
}
]
}
} | [] |
Mutational analysis of a DNA sequence involved in linking gene expression to the cell cycle. | {
"entities": {}
} | [] |
The natural history of these lesions, locoregional efficiency of the different treatments used, the part played by chemotherapy, survival, causes of death and therapeutic modalities used as a last measure, have been analysed. | {
"entities": {}
} | [] |
The method was adapted for the determination of nadolol racemate A by a change in mobile phase composition. | {
"entities": {}
} | [] |
In general, however, this study provided little evidence of any effect of supplementation to athletic performance for athletes consuming the dietary RDIs. | {
"entities": {}
} | [] |
In 7 of 9 cases, the enhancer is fused to the c-myc bearing sequences of chromosome 8. | {
"entities": {
"gene": [
{
"text": "c-myc bearing sequences",
"start": 46,
"end": 69
}
]
}
} | [] |
These components both had a median R2 of 0. 84, compared to median R2s ranging from 0. 37 to 0. 83 for five commonly used ad hoc EEG components. | {
"entities": {}
} | [] |
The obtained results were compared with control group (10 female volunteers). | {
"entities": {}
} | [] |
100 years of dentistry at the Friedrich Schiller University in Jena | {
"entities": {}
} | [] |
The target contained between positions-403 and-125 acts independently of orientation, in different cell types and species, and in the context of a heterologous promoter. | {
"entities": {}
} | [] |
Synergistic transactivation of the BMRF1 promoter by the Z/c-myb combination appears to involve direct binding by the Z protein but not the c-myb protein. | {
"entities": {
"gene": [
{
"text": "BMRF1 promoter",
"start": 35,
"end": 49
},
{
"text": "Z",
"start": 57,
"end": 58
},
{
"text": "c-myb",
"start": 59,
"end": 64
},
{
"text": "Z protein",
... | [] |
The UCR core sequence, CGCCATTTT, binds a ubiquitous nuclear factor and mediates negative regulation of MuLV promoter activity. | {
"entities": {}
} | [] |
These studies show that UCRBP binds to various target motifs that are distinct from the UCR motif: the adeno-associated virus P5 promoter and elements in the immunoglobulin light-and heavy-chain genes, as well as elements in ribosomal protein genes. | {
"entities": {
"gene": [
{
"text": "UCRBP",
"start": 24,
"end": 29
},
{
"text": "adeno-associated virus P5 promoter",
"start": 103,
"end": 137
},
{
"text": "immunoglobulin light-and heavy-chain",
"start": 158,
"... | [] |
The cellular sequences 5' to the viral integration site exhibited 85 to 97% identity to several sequences belonging to the mouse L1 family of long interspersed repetitive sequences. | {
"entities": {
"gene": [
{
"text": "mouse L1 family",
"start": 123,
"end": 138
}
]
}
} | [] |
These results indicate that both N-and C-terminal mutations are required to inhibit transrepression by FBR protein and that multiple structural mutations accompanied by posttranslational protein modification alter gene regulation by FBR protein. | {
"entities": {
"gene": [
{
"text": "FBR protein",
"start": 103,
"end": 114
},
{
"text": "FBR protein",
"start": 233,
"end": 244
}
]
}
} | [] |
The JS78 mutation changes Gln243 in gp0. 7 to an amber codon, which explains the production of the truncated, 30-kDa gp0. 7-related polypeptide, and implicates the 11-kDa C-terminal domain in host transcription shut-off. | {
"entities": {
"gene": [
{
"text": "30-kDa gp0. 7-related polypeptide",
"start": 110,
"end": 143
}
]
}
} | [] |
The predicted receptor structure includes a cysteine-rich extracellular domain, a single hydrophobic transmembrane domain, and a predicted cytoplasmic serine/threonine kinase domain. | {
"entities": {
"gene": [
{
"text": "cytoplasmic serine/threonine kinase domain",
"start": 139,
"end": 181
}
]
}
} | [] |
Drosophila UbcD1 encodes a highly conserved ubiquitin-conjugating enzyme involved in selective protein degradation. | {
"entities": {
"gene": [
{
"text": "Drosophila UbcD1",
"start": 0,
"end": 16
},
{
"text": "ubiquitin",
"start": 44,
"end": 53
}
]
}
} | [] |
Analysis of the entire 16. 7-kb mt genome determined that a MDP1 mediates cleavage of chick mtDNA in vitro at three H-and two L-strand sequence-specific target sites located within a 90-bp A + T-rich genomic tract, theoretically capable of forming stable secondary structures, approximately 200 bases upstream from the H... | {
"entities": {
"gene": [
{
"text": "MDP1",
"start": 60,
"end": 64
}
]
}
} | [] |
The goal of the present study was to determine the feasibility of retrovirus mediated expression of rp47phox in the HL60 and U937 human hematopoietic cell lines, and in an Epstein-Barr virus transformed B-lymphocyte cell line (EBV-BCL) derived from a p47phox-deficient CGD patient. | {
"entities": {
"gene": [
{
"text": "rp47phox",
"start": 100,
"end": 108
},
{
"text": "p47phox",
"start": 251,
"end": 258
}
]
}
} | [] |
A rather similar pattern of results was obtained with respect to LMP2B mRNA expression, such transcripts being detectable only in a subset of tumors, and then at apparently low levels. | {
"entities": {
"gene": [
{
"text": "LMP2B mRNA",
"start": 65,
"end": 75
}
]
}
} | [] |
Analysis of nucleotide sequence of the rightmost 43 kbp of herpesvirus saimiri (HVS) L-DNA: general conservation of genetic organization between HVS and Epstein-Barr virus. | {
"entities": {}
} | [] |
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