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Necrosis appears 6 h after TA infusion, being 5. 77% in extent after 12 h, 14. 9% after 24 h and animals die with an area of 29. 5% necrosis.
{ "entities": {} }
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In summary, the segments of C3 represented by amino acid residues 1082-1118, 1117-1155, 1234-1294 and 1312-1404 accommodate C3 (D) epitopes that are expressed by erythrocyte-bound C3 fragments, but not by the corresponding fluid-phase fragment, whereas the segments spanning residues 973-1026 and 1477-1510 contain C3 (D...
{ "entities": { "gene": [ { "text": "C3", "start": 28, "end": 30 }, { "text": "C3 (D) epitopes", "start": 124, "end": 139 }, { "text": "C3 fragments", "start": 180, "end": 192 }, { "text": "C3...
[]
These exons, further identified as exons 9, 10, and 11, together encode the 37 amino acid residues present in alpha s1-casein variant A but missing in variant F.
{ "entities": { "gene": [ { "text": "alpha s1-casein variant A", "start": 110, "end": 135 } ] } }
[]
We also report here the complete structural organization of the goat alpha s1-casein transcription unit, deduced from polymerase chain reaction experiments.
{ "entities": { "gene": [ { "text": "goat alpha s1-casein transcription unit", "start": 64, "end": 103 } ] } }
[]
Homodimers of the three proteins specifically recognize the G-box motif, with GBF1 and GBF3 binding symmetrically to this palindromic sequence.
{ "entities": { "gene": [ { "text": "GBF1", "start": 78, "end": 82 }, { "text": "GBF3", "start": 87, "end": 91 } ] } }
[]
The hydrophobicity plot of NHE-3 is very similar to that of NHE-1 and NHE-2.
{ "entities": { "gene": [ { "text": "NHE-3", "start": 27, "end": 32 }, { "text": "NHE-1", "start": 60, "end": 65 }, { "text": "NHE-2", "start": 70, "end": 75 } ] } }
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The initial translation protein encoded by the cDNA is 53, 932 kDa and possesses a hydrophilic amino acid composition with glutamic acid comprising 22% of the total amino acid residues.
{ "entities": {} }
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Each group received 15 ml/kg of either 6% pentafraction, 6% pentastarch, or plasma followed two hours later by 1. 5 micrograms/kg/0. 5 hr E.
{ "entities": {} }
[]
Genetic and biochemical evidence suggests that v-Crk can induce transformation of chicken embryo fibroblasts by influencing the activity of cellular proteins involved in growth regulation.
{ "entities": { "gene": [ { "text": "v-Crk", "start": 47, "end": 52 } ] } }
[]
We have constructed, using synthetic DNA oligonucleotides, a U14 snRNA gene which has been positioned behind a T7 RNA polymerase promoter site and then inserted into a plasmid.
{ "entities": { "gene": [ { "text": "U14 snRNA gene", "start": 61, "end": 75 }, { "text": "T7 RNA polymerase promoter site", "start": 111, "end": 142 } ] } }
[]
The carcinoma was restricted within the epithelium in one, the mucosal layer in five, and the submucosal layer in two.
{ "entities": {} }
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In addition, C/EBP beta and C/EBP gamma readily heterodimerize with each other as well as with C/EBP alpha.
{ "entities": { "gene": [ { "text": "C/EBP beta", "start": 13, "end": 23 }, { "text": "C/EBP gamma", "start": 28, "end": 39 }, { "text": "C/EBP alpha", "start": 95, "end": 106 } ] } }
[]
In contrast, tobacco GS-2 is composed of subunits of identical size in all organs examined.
{ "entities": { "gene": [ { "text": "tobacco GS-2", "start": 13, "end": 25 } ] } }
[]
Between acoR and acoXABC, two different types of sequences with dual rotational symmetry [CAC-(N11 to N18)-GTG and TGT-(N10 to N14)-ACA] were found; these sequences are similar to NtrC and NifA upstream activator sequences, respectively.
{ "entities": { "gene": [ { "text": "acoR", "start": 8, "end": 12 }, { "text": "acoXABC", "start": 17, "end": 24 }, { "text": "NtrC", "start": 180, "end": 184 }, { "text": "NifA upstream activ...
[]
Although the effects of the calcium supplement or calcium antagonist alone were significant, such hypotensive responses were not optimal or predictable or clearly dose-dependent.
{ "entities": {} }
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C., Sun, J., Hsu, M.-Y., Vallejo-Ramirez, J., Inouye, S., and Inouye, M.
{ "entities": {} }
[]
Surprisingly, the full-deletion mutant showed a strong block in virus release, suggesting that NC is involved in virus assembly.
{ "entities": { "gene": [ { "text": "NC", "start": 95, "end": 97 } ] } }
[]
Furthermore it was suggested that FK506 plasma levels were concerned with the appearance of side effect.
{ "entities": {} }
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Thirty percent of patients were tapered off all steroids, and the average steroid dose in the group who received steroids was 8. 6 mg of prednisone per day.
{ "entities": {} }
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Thus, cibenzoline is an effective antiarrhythmic agent with a favourable pharmacokinetic profile that may be considered with other class I drugs in patients requiring therapy for high risk arrhythmias.
{ "entities": {} }
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T antigen contains four H-2Db-restricted cytotoxic T lymphocyte (CTL) recognition epitopes that are targets for CTL clones Y-1, Y-2, Y-3, and Y-5.
{ "entities": { "gene": [ { "text": "T antigen", "start": 0, "end": 9 } ] } }
[]
The method requires a reversed-phase column and a paired-ion technique to separate docusate sodium from other components.
{ "entities": {} }
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Here we demonstrate that the protein product of the ref-1 gene stimulates the DNA binding activity of Fos-Jun heterodimers, Jun-Jun homodimers and Hela cell AP-1 proteins as well as that of several other transcription factors including NF-kappa B, Myb and members of the ATF/CREB family.
{ "entities": { "gene": [ { "text": "ref-1 gene", "start": 52, "end": 62 }, { "text": "Fos", "start": 102, "end": 105 }, { "text": "Jun", "start": 106, "end": 109 }, { "text": "Jun", "...
[]
The pulpal tissues of the permanent mandibular molars were amputated and then dressed with calcium hydrate.
{ "entities": {} }
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Northern blot analyses demonstrate that 3. 9-and 5-kilobase mRNAs corresponding to the cDNA were present in all tissues examined, suggesting that the protein it encodes performs a housekeeping function.
{ "entities": {} }
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The ARG SH2 domain exhibited relatively weak affinity for BCR and was determined to bind about 10-fold less strongly than the ABL SH2 domain.
{ "entities": { "gene": [ { "text": "ARG SH2 domain", "start": 4, "end": 18 }, { "text": "BCR", "start": 58, "end": 61 }, { "text": "ABL SH2 domain", "start": 126, "end": 140 } ] } }
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We analyzed an EBV B-cell clone, E29. 1, derived from an 11 week-old embryo, and secreting both IgM kappa and IgM lambda.
{ "entities": { "gene": [ { "text": "IgM kappa", "start": 96, "end": 105 }, { "text": "IgM lambda", "start": 110, "end": 120 } ] } }
[]
Interestingly, this activation occurred only when the regions were cloned in the same relative orientation in which they exist on wild-type pCF10.
{ "entities": {} }
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In rats, we examined the effect of an omentum wrapping on the vascularization of the trachea and on regeneration of the mucosal epithelium in the very early stage after free tracheal grafting.
{ "entities": {} }
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To study a possible functional role of this putative chicken ICS, an oligonucleotide spanning the upstream sequences of the BF-IV gene (-174/-194) was cloned singly or in multiple copies before the herpes TK promoter controlling the chloramphenicol acetyl transferase (CAT) gene (pBLCAT2).
{ "entities": { "gene": [ { "text": "ICS", "start": 61, "end": 64 }, { "text": "BF-IV gene", "start": 124, "end": 134 }, { "text": "TK promoter", "start": 205, "end": 216 }, { "text": "chloram...
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In general, two separate high-performance liquid chromatographic runs were performed, one for the gamma-aminobutyric acid determination and one for the determination of the monoamines.
{ "entities": {} }
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We report the successful use of electroconvulsive therapy for treatment of severe depression in a young man with adult GM2 gangliosidosis.
{ "entities": {} }
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Through Southern blot analyses of DNA from backcross and cogenic mice, recombinant inbred strains, and somatic cell hybrids, the genetic loci that produce the cyclin B1-related sequences (designated loci Cycb1-rs1 to Cycb1-rs9) were mapped on mouse chromosomes 5, 1, 17, 4, 14, 13, 7, X, and 8, respectively.
{ "entities": { "gene": [ { "text": "cyclin B1-related sequences", "start": 159, "end": 186 }, { "text": "loci Cycb1-rs1", "start": 199, "end": 213 }, { "text": "Cycb1-rs9", "start": 217, "end": 226 } ]...
[]
Again residue Glu-381 of beta was notably reduced and no missing residue from the epsilon peptide could be identified, but the peptide sequence limited the possible choices to Ser-106, Ser-107, or Ser-108.
{ "entities": {} }
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Porcelain to dentin bond strength with a dentin adhesive.
{ "entities": {} }
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TBPf is defined as a quotient of the difference of the first and the second measurement: TBPf = (P1-P2)/(A1-A2).
{ "entities": {} }
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It was concluded that Scotchbond 2 and Prisma Universal Bond 2 are effective and are the dentine bonding agents of choice.
{ "entities": {} }
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The neurohypophysial vasopressin and oxytocin content was bioassayed by pressor effect following Dekanski or milk-ejection activity in vitro following van Dongen and Hays, respectively.
{ "entities": { "gene": [ { "text": "vasopressin", "start": 21, "end": 32 }, { "text": "oxytocin", "start": 37, "end": 45 } ] } }
[]
Comments are given on the present status of regulations concerning water in swimming pools and baths--1991--(in connection with the KOK regulations--1972--and the Federal German standard [DIN] No.
{ "entities": {} }
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If no reply was received, telephone contact or home visits were made.
{ "entities": {} }
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The treatment group also showed in vivo T-cell activation with an initial lymphopenia followed by a rebound lymphocytosis and upregulation of the subset markers CD25 (interleukin 2 receptor) and CD45RO (T-memory cells).
{ "entities": { "gene": [ { "text": "CD25", "start": 161, "end": 165 }, { "text": "interleukin 2 receptor", "start": 167, "end": 189 }, { "text": "CD45RO", "start": 195, "end": 201 } ] } }
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Urease activity, judged as the amount of ammonia production from urea, could be measured at 25 ng per tube (S/N = 1. 5) with Jack bean meal urease.
{ "entities": { "gene": [ { "text": "Urease", "start": 0, "end": 6 }, { "text": "Jack bean meal urease", "start": 125, "end": 146 } ] } }
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Although a wide range of cognitive functions had been tested, all but one seizure occurred during assessment of memory performance.
{ "entities": {} }
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The experiments show that it is the micromilieu of the alveoli and the condition of the AM (certain physiological activation states, such as phagocytic activity) that essentially determine the degree of recovery.
{ "entities": {} }
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A cDNA library of tumour cells was screened with an interleukin 2 gene-specific probe.
{ "entities": { "gene": [ { "text": "interleukin 2", "start": 52, "end": 65 } ] } }
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Our experiments suggest that the SCL gene can be a target for the erythroid transcription factor GATA-1 and that the SCL gene product serves as a positive regulator of erythroid differentiation.
{ "entities": { "gene": [ { "text": "SCL gene", "start": 33, "end": 41 }, { "text": "erythroid transcription factor GATA-1", "start": 66, "end": 103 }, { "text": "SCL gene product", "start": 117, "end": 133 ...
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Complexes containing wild-type and either his175 or his273 mutant p53 proteins are completely unable to bind to the RGC DNA sequence.
{ "entities": { "gene": [ { "text": "his175 or his273 mutant p53 proteins", "start": 42, "end": 78 }, { "text": "RGC DNA sequence", "start": 116, "end": 132 } ] } }
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These temperature-and cold-sensitive strains were used to prepare extracts deficient in BRF1 activity and were tested for transcriptional activity by RNA polymerases I, II, and III in vitro.
{ "entities": { "gene": [ { "text": "BRF1", "start": 88, "end": 92 }, { "text": "RNA polymerases I, II, and III", "start": 150, "end": 180 } ] } }
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These results lead us to hypothesize that a single multisubunit TFIID protein supports transcriptional stimulation by diverse activation domains and from a TATA-less promoter.
{ "entities": { "gene": [ { "text": "multisubunit TFIID protein", "start": 51, "end": 77 } ] } }
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Clone pSRc200 hybrid selected an mRNA that on cell-free translation produced a 38-kDa polypeptide.
{ "entities": {} }
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From these results, CBF-A is a novel CArG box-, ssDNA-and RNA-binding protein, as well as a repressive transcriptional factor.
{ "entities": { "gene": [ { "text": "CBF-A", "start": 20, "end": 25 }, { "text": "ssDNA-and RNA-binding protein", "start": 48, "end": 77 } ] } }
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Cleavage by the intron-encoded enzyme (I-CreI) occurs 5 bp and 1 bp 3' to the intron insertion site (in the 3'-exon) in the top (/) and bottom (,) strands, respectively, resulting in 4-nt single-stranded overhangs with 3'-OH termini.
{ "entities": { "gene": [ { "text": "I-CreI", "start": 39, "end": 45 } ] } }
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Surprisingly, the Xenopus U7 gene contains two adjacent octamer-binding motifs located only 12 and 24 bp upstream from the PSE, instead of the usual location around 150-200 bp upstream.
{ "entities": { "gene": [ { "text": "Xenopus U7 gene", "start": 18, "end": 33 }, { "text": "PSE", "start": 123, "end": 126 } ] } }
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The results support earlier reports that collagenase inhibitors are useful in controlling blister formation in recessive dystrophic epidermolysis bullosa.
{ "entities": { "gene": [ { "text": "collagenase", "start": 41, "end": 52 } ] } }
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In humans, four AMP deaminase variants, termed M (muscle), L (liver), E1, and E2 (erythrocyte) can be distinguished by a variety of biochemical and immunological criteria.
{ "entities": { "gene": [ { "text": "AMP deaminase variants", "start": 16, "end": 38 }, { "text": "M", "start": 47, "end": 48 }, { "text": "L", "start": 59, "end": 60 }, { "text": "E1", ...
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Western blot analyses detect anti-E-specific immunoreactivity in affinity-purified extracts derived from the bacterial expression of a truncated AMPD3 cDNA.
{ "entities": { "gene": [ { "text": "anti-E", "start": 29, "end": 35 }, { "text": "truncated AMPD3 cDNA", "start": 135, "end": 155 } ] } }
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These results demonstrate that endogenous N-methylation of salsolinol into N-methylsalsolinol occurs in the brain in vivo.
{ "entities": {} }
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DR1 molecules purified from human lymphoblastoid cell lines could specifically bind to these peptide sequences expressed on the phage surface.
{ "entities": { "gene": [ { "text": "DR1 molecules", "start": 0, "end": 13 } ] } }
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This article describes the collaborative care of the woman participating in maternal blood donation for intrauterine transfusion.
{ "entities": {} }
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Chronic hepatitis B in adopted Romanian children.
{ "entities": {} }
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Behind the ATPase cluster, two open reading frames were detected that are not homologous to any known chloroplast gene.
{ "entities": { "gene": [ { "text": "ATPase cluster", "start": 11, "end": 25 } ] } }
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Therefore, recombinant human Ads that express noninfectious HIV or other microbial proteins are attractive vaccine candidates.
{ "entities": {} }
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Alignment of the selected sequences allowed us to predict a consensus sequence for binding of the individual homodimeric Rel-related proteins, and DNA-protein binding analysis of the selected DNA sequences revealed sequence specificity of the proteins.
{ "entities": { "gene": [ { "text": "Rel-related proteins", "start": 121, "end": 141 } ] } }
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Using either a p50-or p65-selected kappa B motif, which displayed differential binding with respect to the other protein, little to no binding was observed with the heterodimeric NF-kappa B complex.
{ "entities": { "gene": [ { "text": "p50", "start": 15, "end": 18 }, { "text": "p65-selected kappa B motif", "start": 22, "end": 48 }, { "text": "heterodimeric NF-kappa B complex", "start": 165, "end": 197 ...
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However, a cosmid clone containing the entire mouse alpha 1 (I) gene, including 3. 7 kb of 5'-and 4 kb of 3'-flanking DNA, was expressed at reduced levels in fibroblasts overexpressing oncogenic ras.
{ "entities": { "gene": [ { "text": "mouse alpha 1 (I) gene", "start": 46, "end": 68 }, { "text": "oncogenic ras", "start": 185, "end": 198 } ] } }
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To define transcriptional control elements responsible for muscle-specific expression of the human myoglobin gene, we performed mutational analysis of upstream sequences (nucleotide positions-373 to + 7 relative to the transcriptional start site) linked to a firefly luciferase gene.
{ "entities": { "gene": [ { "text": "human myoglobin gene", "start": 93, "end": 113 }, { "text": "firefly luciferase gene", "start": 259, "end": 282 } ] } }
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Sequencing analysis has shown that each rap1t allele contains a nonsense mutation within a discrete region between amino acids 663 and 684.
{ "entities": { "gene": [ { "text": "rap1t allele", "start": 40, "end": 52 } ] } }
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By screening a Y1 cell cDNA library with the DNA-binding region of the H-2RIIBP nuclear hormone receptor cDNA, we isolated a cDNA that is selectively expressed in steroidogenic cells.
{ "entities": { "gene": [ { "text": "H-2RIIBP nuclear hormone receptor cDNA", "start": 71, "end": 109 } ] } }
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Autopsy demonstrated good survival of the transplanted cells with good integration with the brain of the recipient and traces of positive immunocytochemical reaction for tyrosine hydroxylase.
{ "entities": { "gene": [ { "text": "tyrosine hydroxylase", "start": 170, "end": 190 } ] } }
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The technique of the TEE visualization of the proximal coronary arteries is described.
{ "entities": {} }
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The sequence of this region shows high G + C content (62%), which is particularly emphasized in the 200 bp upstream from the mRNA start (80% G + C).
{ "entities": {} }
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PaO2 threshold was determined through an indwelling O2 sensor catheter.
{ "entities": {} }
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By using lambda gt11 expression cloning with oligonucleotides corresponding to the human immunodeficiency virus 1 TATA element, we report the identification of a cellular protein with a calculated molecular mass of 123 kDa that we designate TATA element modulatory factor (TMF).
{ "entities": { "gene": [ { "text": "TATA element modulatory factor", "start": 241, "end": 271 }, { "text": "TMF", "start": 273, "end": 276 } ] } }
[]
Blood levels of melatonin, serotonin, cortisol, and prolactin in relation to the circadian rhythm of platelet serotonin uptake.
{ "entities": { "gene": [ { "text": "prolactin", "start": 52, "end": 61 } ] } }
[]
We couldn' t detect any effect of n-3 FA supplementation on total cholesterol, HDL cholesterol, LDL cholesterol, apo A1, Lp (a), HbA1C, glucose, fibrinogen, factor VIII, antithrombin III, plasminogen activator inhibitor, tissue plasminogen activator and von Willebrand factor concentration, on bleeding time or on systol...
{ "entities": { "gene": [ { "text": "HDL cholesterol", "start": 79, "end": 94 }, { "text": "LDL cholesterol", "start": 96, "end": 111 }, { "text": "apo A1", "start": 113, "end": 119 }, { "text...
[]
In 8 healthy volunteers there were no significant differences in AUC, peak plasma concentrations or time to peak concentration when OXC was administered either with or without ERY.
{ "entities": {} }
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Using 5 ng/mL as the cutoff, the sensitivity of CEA was 68%.
{ "entities": { "gene": [ { "text": "CEA", "start": 48, "end": 51 } ] } }
[]
Rolandic spikes and cognitive function.
{ "entities": {} }
[]
The effect of sodium 18 beta-glycyrrhetate (SGA) on experimental arrhythmia was investigated.
{ "entities": {} }
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Thus, chronic hematocrit decrease induced by H or P resulted in a significant fall in blood pressure compared to control (201 +/-3 v 175 +/-4, 167 +/-4 mm Hg, respectively; P <. 05).
{ "entities": {} }
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The effects of diltiazem were stereoselective, thus the potentiation induced by d-cis diltiazem was significantly greater in all cases than that induced by l-cis diltiazem, which suggests that calcium channel blockade plays a role in these interactions.
{ "entities": {} }
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Substitution of either Val33 (by Gly) or Gly28 (by Ser), two of the most conserved residues in all protein kinases, resulted in enzyme with marginally detectable activity.
{ "entities": {} }
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Significance of the biopsy site of the latissimus dorsi muscle for fiber typing.
{ "entities": {} }
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The TIMP (-59/-53) AP1 site is a promiscuous motif that binds c-Fos/c-Jun AP1 translated in vitro and is an effective competitor for binding of nuclear AP1 factors to the consensus TRE, but in addition it binds factors that do not associate with the consensus TRE.
{ "entities": { "gene": [ { "text": "TIMP", "start": 4, "end": 8 }, { "text": "AP1", "start": 19, "end": 22 }, { "text": "c-Fos", "start": 62, "end": 67 }, { "text": "c-Jun AP1", "star...
[]
Involvement of AP1 and PEA3 binding sites in the regulation of murine tissue inhibitor of metalloproteinases-1 (TIMP-1) transcription.
{ "entities": { "gene": [ { "text": "AP1", "start": 15, "end": 18 }, { "text": "PEA3 binding sites", "start": 23, "end": 41 }, { "text": "murine tissue inhibitor of metalloproteinases-1", "start": 63, "end": 110 ...
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Of the serum neutralizing (SN) antibody negative calves 89. 7% (26/29) and 92. 8% (90/97) developed SN antibody 1 month after intranasal and intramuscular vaccination, respectively.
{ "entities": { "gene": [ { "text": "serum neutralizing (SN) antibody", "start": 7, "end": 39 }, { "text": "SN antibody", "start": 100, "end": 111 } ] } }
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Fractionation of crude nuclear extracts by heparin-agarose chromatography indicates that PCAT-1 is more prevalent in extracts prepared from salt-stressed leaf tissue.
{ "entities": { "gene": [ { "text": "PCAT-1", "start": 89, "end": 95 } ] } }
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A controlled trial of recombinant human granulocyte-macrophage colony-stimulating factor after total body irradiation, high-dose chemotherapy, and autologous bone marrow transplantation for acute lymphoblastic leukemia or malignant lymphoma.
{ "entities": { "gene": [ { "text": "recombinant human granulocyte-macrophage colony-stimulating factor", "start": 22, "end": 88 } ] } }
[]
These data demonstrate that DMVA does not cause more myocardial trauma than CPB when used to provide resuscitative circulatory support.
{ "entities": {} }
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The IgG subclass profile of untreated coeliac disease was found to be the same as in healthy controls (IgG1 approximately IgG2 > IgG3 > IgG4), with only the magnitude of the individual subclass responses being increased in coeliac patients.
{ "entities": { "gene": [ { "text": "IgG", "start": 4, "end": 7 }, { "text": "IgG1", "start": 103, "end": 107 }, { "text": "IgG2", "start": 122, "end": 126 }, { "text": "IgG3", "start"...
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Examination of ANCA is not only a significant contribution towards a more accurate diagnosis of renal vasculitis, but also an indicator of the activity of the disease and thus of the effectiveness of immunosuppressive treatment.
{ "entities": { "gene": [ { "text": "ANCA", "start": 15, "end": 19 } ] } }
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On the other hand, total pinealectomy in these already sympathectomized blinded rabbits always resulted in a substantial deceleration of the rhythms (mean delta tau = + 0. 23 h).
{ "entities": {} }
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Cicatricial pemphigoid is an autoimmune systemic disease characterized by chronic conjunctival cicatrization.
{ "entities": {} }
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The effects of two levels of caffeine ingestion on excess postexercise oxygen consumption in untrained women.
{ "entities": {} }
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The distinguishing features involved eight amino acid changes, including a single lysine deletion relative to a primate consensus sequence in the first complementary-determing region of V1J1.
{ "entities": { "gene": [ { "text": "V1J1", "start": 186, "end": 190 } ] } }
[]
4.
{ "entities": {} }
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The in vivo profile of ZFH-2 in the larval CNS shows intriguing overlap with DDC in specific serotonin and dopamine neurons.
{ "entities": { "gene": [ { "text": "ZFH-2", "start": 23, "end": 28 }, { "text": "DDC", "start": 77, "end": 80 } ] } }
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Unlike the introns of other duplicated ribosomal protein genes which are highly diverged, the duplicated S13 genes have two nearly identical DNA sequences of 25 and 31 bp in length within their introns.
{ "entities": { "gene": [ { "text": "ribosomal protein genes", "start": 39, "end": 62 }, { "text": "S13 genes", "start": 105, "end": 114 } ] } }
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In a prospective, randomized clinical trial we compared the efficacy of subcutaneously (SC) administered (every 8 h) calcium heparin to intravenous (IV) sodium heparin in the treatment of proximal deep-vein thrombosis (DVT).
{ "entities": {} }
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The highest prevalence of reported pet allergy, chronic cough, wheeze, attacks of shortness of breath with wheezing, and doctor-diagnosed asthma was found in children who had pets in the past but not anymore.
{ "entities": {} }
[]