input stringlengths 2 974 | output dict | schema listlengths 0 0 |
|---|---|---|
Treatment with MK-801 induced a burst suppression in the EEG and a transient drop (11. 4 +/-6. 5 mm Hg) in the mean arterial pressure. | {
"entities": {}
} | [] |
Myogenic differentiation can be inhibited by the adenovirus E1a protein in the rat L6 muscle cell line. | {
"entities": {
"gene": [
{
"text": "E1a protein",
"start": 60,
"end": 71
}
]
}
} | [] |
Acad. | {
"entities": {}
} | [] |
Both in vitro-synthesized S2 protein and synthetic peptides corresponding to S2 are shown to react positively with sera obtained from EIAV-infected horses, providing the first direct evidence of expression of this protein in infected animals. | {
"entities": {
"gene": [
{
"text": "S2 protein",
"start": 26,
"end": 36
},
{
"text": "S2",
"start": 77,
"end": 79
}
]
}
} | [] |
Many canonical TATA sequences are present upstream from these VZV transcriptional start sites but, apparently, are not used. | {
"entities": {}
} | [] |
The ORF 4 gene was minimally active, whereas the ORF 62 gene gave twofold induction; both genes, acting together, gave fivefold induction. | {
"entities": {}
} | [] |
Interestingly, the IR5 ORF of EHV-1 possesses a sequence of 13 amino acids (CAYWCCLGHAFAC) that is a perfect match to the consensus zinc finger motif (C-X2-4-C-X2-15-C/H-X2-4-C/H). | {
"entities": {
"gene": [
{
"text": "IR5 ORF",
"start": 19,
"end": 26
}
]
}
} | [] |
The DNA sequence of the sulfate activation locus from Escherichia coli K-12 has been determined. | {
"entities": {
"gene": [
{
"text": "sulfate activation locus",
"start": 24,
"end": 48
}
]
}
} | [] |
Plasma membranes of cultured cells contain high affinity receptors for high density lipoprotein (HDL) that appear to mediate removal of excess intracellular cholesterol. | {
"entities": {
"gene": [
{
"text": "high density lipoprotein",
"start": 71,
"end": 95
},
{
"text": "HDL",
"start": 97,
"end": 100
}
]
}
} | [] |
After the first 28 patients vincristine was replaced by teniposide (VM-26) due to neurotoxicity. | {
"entities": {}
} | [] |
These results indicate that an internal short element located at the very 5' terminal of L1 sequence and the nuclear factor binding to the element play a crucial role in the transcription of human L1. | {
"entities": {
"gene": [
{
"text": "L1 sequence",
"start": 89,
"end": 100
},
{
"text": "human L1",
"start": 191,
"end": 199
}
]
}
} | [] |
Tumor cells were focally immunoreactive for neuron-specific enolase, insulin, glucagon and VIP. | {
"entities": {
"gene": [
{
"text": "neuron-specific enolase",
"start": 44,
"end": 67
},
{
"text": "insulin",
"start": 69,
"end": 76
},
{
"text": "glucagon",
"start": 78,
"end": 86
},
{
"text"... | [] |
A recombinant with a 5' end from src and a 3' end from ros, called SRC x ROS, transformed chicken embryo fibroblasts (CEF) to a spindle shape morphology, mimicking that of UR2. | {
"entities": {
"gene": [
{
"text": "src",
"start": 33,
"end": 36
},
{
"text": "ros",
"start": 55,
"end": 58
},
{
"text": "SRC",
"start": 67,
"end": 70
},
{
"text": "ROS",
"start": 73,... | [] |
ROS x SRC (R) contains a 16-amino-acid deletion that includes the 3' half of the transmembrane domain of ros. | {
"entities": {
"gene": [
{
"text": "ROS",
"start": 0,
"end": 3
},
{
"text": "SRC",
"start": 6,
"end": 9
},
{
"text": "R",
"start": 11,
"end": 12
},
{
"text": "ros",
"start": 105,
... | [] |
To define the number and nature of the E6 and E7 gene products expressed in BPV-1-transformed cells, we performed immunoprecipitation experiments with antisera raised to bacterially expressed BPV-1 E6 and E7 fusion proteins. | {
"entities": {
"gene": [
{
"text": "E6",
"start": 39,
"end": 41
},
{
"text": "E7 gene",
"start": 46,
"end": 53
},
{
"text": "BPV-1 E6",
"start": 192,
"end": 200
},
{
"text": "E7 fusion protei... | [] |
Transient transfection assays showed that site A is necessary and sufficient for RXR alpha-mediated transactivation of the apoAI gene basal promoter in human hepatoma HepG2 cells in the presence of RA and that this transactivation is abolished by increasing amounts of cotransfected ARP-1. | {
"entities": {
"gene": [
{
"text": "RXR alpha",
"start": 81,
"end": 90
},
{
"text": "apoAI gene basal promoter",
"start": 123,
"end": 148
},
{
"text": "ARP-1",
"start": 283,
"end": 288
}
]
}
} | [] |
A third prominent component of apparent molecular mass 16 kDa displayed several properties, including ability to bind 45Ca2 +, that are characteristic of the regulatory (B) subunit of mammalian calcineurin and was recognized by an antiserum raised against bovine calcineurin. | {
"entities": {
"gene": [
{
"text": "mammalian calcineurin",
"start": 184,
"end": 205
},
{
"text": "bovine calcineurin",
"start": 256,
"end": 274
}
]
}
} | [] |
As was observed previously for MATa cna1 cna2 double mutants, MATa cnb1 mutants were defective in their ability to recover from alpha-factor-induced growth arrest. | {
"entities": {
"gene": [
{
"text": "MATa cna1 cna2",
"start": 31,
"end": 45
},
{
"text": "MATa cnb1 mutants",
"start": 62,
"end": 79
},
{
"text": "alpha-factor",
"start": 128,
"end": 140
}
]
}
} | [] |
Antibodies against this purified protein localize RIM1 to mitochondria. | {
"entities": {
"gene": [
{
"text": "RIM1",
"start": 50,
"end": 54
}
]
}
} | [] |
METHODS: IgG antibodies vs HHV-6 (anti-HHV-6-IgG) were determined by indirect immunofluorescence in 100 IVDA (29 seronegative and 71 seropositive for HIV-1 of which 45 were in stage II and 26 in IV-C1 of CDC) as well as in 100 healthy subjects of a similar age (control group). | {
"entities": {
"gene": [
{
"text": "IgG antibodies",
"start": 9,
"end": 23
},
{
"text": "anti-HHV-6-IgG",
"start": 34,
"end": 48
}
]
}
} | [] |
A position-independent activation domain which contained conserved regions II and III was identified at the carboxyl terminus of the HNF-3 beta protein (amino acids 361 to 458). | {
"entities": {
"gene": [
{
"text": "HNF-3 beta protein",
"start": 133,
"end": 151
}
]
}
} | [] |
HNF-3 beta amino-terminal sequences defined by conserved region IV also contributed to transactivation, but region IV activity required the participation of the region II-III domain. | {
"entities": {
"gene": [
{
"text": "HNF-3 beta amino-terminal sequences",
"start": 0,
"end": 35
}
]
}
} | [] |
Possible roles of RAD5 putative ATPase/DNA helicase activity in DNA repair and in the maintenance of wild-type rates of instability of simple repetitive sequences are discussed. | {
"entities": {
"gene": [
{
"text": "RAD5",
"start": 18,
"end": 22
},
{
"text": "ATPase",
"start": 32,
"end": 38
},
{
"text": "DNA helicase",
"start": 39,
"end": 51
}
]
}
} | [] |
Susceptibilities of 540 anaerobic gram-negative bacilli to amoxicillin, amoxicillin-BRL 42715, amoxicillin-clavulanate, temafloxacin, and clindamycin. | {
"entities": {}
} | [] |
Nocodazole arrest of DU249 cells was exploited for the detection of an M-phase-activated MBP kinase that was resolved from p41 MAP kinase by phenyl-Superose chromatography. | {
"entities": {
"gene": [
{
"text": "MBP kinase",
"start": 89,
"end": 99
},
{
"text": "p41 MAP kinase",
"start": 123,
"end": 137
}
]
}
} | [] |
The hit1-1 mutation caused a defect in synthesis of a 74-kD heat shock protein. | {
"entities": {
"gene": [
{
"text": "hit1-1",
"start": 4,
"end": 10
},
{
"text": "74-kD heat shock protein",
"start": 54,
"end": 78
}
]
}
} | [] |
The 319 base pair region immediately upstream of the CAP site is characterized by the lack of a proximal TATA box and the presence of sequences similar to GC boxes, CACCC boxes, CCAAT boxes, activator protein 2 (Ap-2) sites, partial glucocorticoid response elements (GREs), and partial cyclic AMP response elements (CREs... | {
"entities": {
"gene": [
{
"text": "activator protein 2",
"start": 191,
"end": 210
},
{
"text": "Ap-2",
"start": 212,
"end": 216
}
]
}
} | [] |
In rats anaesthetized with +-chloralose the changes in extracellular pH and K + in spinal cord dorsal horn were studied using pH and K + ion-selective electrodes. | {
"entities": {}
} | [] |
Replication of bovine papillomavirus-1 (BPV-1) DNA requires two viral gene products, the E1 protein and the full-length E2 protein. | {
"entities": {
"gene": [
{
"text": "E1 protein",
"start": 89,
"end": 99
},
{
"text": "full-length E2 protein",
"start": 108,
"end": 130
}
]
}
} | [] |
Insertional inactivation of sms led to increased sensitivity to the alkylating agent methylmethane sulfonate, but not to a requirement for serine or other metabolites. | {
"entities": {
"gene": [
{
"text": "sms",
"start": 28,
"end": 31
}
]
}
} | [] |
These findings suggest that the MAP kinase activator/MAP kinase system may be the downstream components of ras signal transduction pathways. | {
"entities": {
"gene": [
{
"text": "MAP kinase activator",
"start": 32,
"end": 52
},
{
"text": "MAP kinase",
"start": 53,
"end": 63
},
{
"text": "ras",
"start": 107,
"end": 110
}
]
}
} | [] |
NSCL-1 is expressed in a larger number of these cell lines. | {
"entities": {
"gene": [
{
"text": "NSCL-1",
"start": 0,
"end": 6
}
]
}
} | [] |
Labile LTR-binding proteins appear to be essential for c-myc hyperexpression, since both LTR-enhanced transcription and the activities of LTR-binding proteins are specifically decreased after inhibition of protein synthesis (A. | {
"entities": {
"gene": [
{
"text": "LTR-binding proteins",
"start": 7,
"end": 27
},
{
"text": "c-myc",
"start": 55,
"end": 60
},
{
"text": "LTR-binding proteins",
"start": 138,
"end": 158
}
]
}
} | [] |
Ruddell, M. | {
"entities": {}
} | [] |
A single MEF-2 site is a major positive regulatory element required for transcription of the muscle-specific subunit of the human phosphoglycerate mutase gene in skeletal and cardiac muscle cells. | {
"entities": {
"gene": [
{
"text": "MEF-2 site",
"start": 9,
"end": 19
},
{
"text": "human phosphoglycerate mutase gene",
"start": 124,
"end": 158
}
]
}
} | [] |
Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs. | {
"entities": {
"gene": [
{
"text": "MHC class II molecules",
"start": 46,
"end": 68
}
]
}
} | [] |
Although the E-box consensus is minimally defined as CANNTG, the adjacent nucleotides of functional E-boxes are variable for genes regulated by the bHLH proteins. | {
"entities": {
"gene": [
{
"text": "bHLH proteins",
"start": 148,
"end": 161
}
]
}
} | [] |
Intermediate levels of gene activity were observed for TnI enhancers containing E-boxes derived from the MCK left E-box site or from the Ig kappa E2 E-box. | {
"entities": {
"gene": [
{
"text": "TnI enhancers",
"start": 55,
"end": 68
},
{
"text": "MCK left E-box site",
"start": 105,
"end": 124
},
{
"text": "Ig kappa E2 E-box",
"start": 137,
"end": 154
}
]
... | [] |
T-cell receptor beta (TCR beta) gene rearrangements occur in a third of early B-cell acute lymphoblastic leukemias (ALLs). | {
"entities": {
"gene": [
{
"text": "T-cell receptor beta",
"start": 0,
"end": 20
},
{
"text": "TCR beta",
"start": 22,
"end": 30
}
]
}
} | [] |
The CANNTG motifs were found to bind MyoD and myogenin fusion proteins and to interact with proteins in nuclear extracts from cultured myotubes. | {
"entities": {
"gene": [
{
"text": "MyoD",
"start": 37,
"end": 41
},
{
"text": "myogenin fusion proteins",
"start": 46,
"end": 70
}
]
}
} | [] |
Peripheral polyneuropathy associated with multiple myeloma. | {
"entities": {}
} | [] |
We have cloned and sequenced COX12, the nuclear gene for subunit VIb of Saccharomyces cerevisiae cytochrome c oxidase. | {
"entities": {
"gene": [
{
"text": "COX12",
"start": 29,
"end": 34
},
{
"text": "subunit VIb",
"start": 57,
"end": 68
},
{
"text": "Saccharomyces cerevisiae cytochrome c oxidase",
"start": 72,
"end": 117
}... | [] |
The structure of the calcineurin A gene was determined by comparison of the genomic and cDNA sequences. | {
"entities": {
"gene": [
{
"text": "calcineurin A gene",
"start": 21,
"end": 39
}
]
}
} | [] |
The basal promoter elements of murine cytochrome c oxidase subunit IV gene consist of tandemly duplicated ets motifs that bind to GABP-related transcription factors. | {
"entities": {
"gene": [
{
"text": "murine cytochrome c oxidase subunit IV gene",
"start": 31,
"end": 74
},
{
"text": "ets",
"start": 106,
"end": 109
},
{
"text": "GABP-related transcription factors",
"start": 130,
... | [] |
Lastly, there are multiple instances in which short oligonucleotide direct repeats flank a region absent from either variola or vaccinia virus. | {
"entities": {}
} | [] |
Here we show that short synthetic peptides containing the pRB-binding sequences of E1A are sufficient for interaction with p107, cyclin A, and p130. | {
"entities": {
"gene": [
{
"text": "pRB-binding sequences",
"start": 58,
"end": 79
},
{
"text": "E1A",
"start": 83,
"end": 86
},
{
"text": "p107",
"start": 123,
"end": 127
},
{
"text": "cycli... | [] |
These mutants grow normally in 3T6 mouse fibroblast cells, and they do not complement the wild-type virus in coinfection experiments of C2 myoblasts. | {
"entities": {}
} | [] |
The MICs of this compound against 90% of these organisms, except for methicillin-resistant S. aureus, ranged from less than or equal to 0. 006 to 3. 13 micrograms/ml. | {
"entities": {}
} | [] |
The minimal promoter of the RII beta gene was composed of two adjacent functional elements. | {
"entities": {
"gene": [
{
"text": "RII beta gene",
"start": 28,
"end": 41
}
]
}
} | [] |
Mapping the cAMP receptor protein contact site on the alpha subunit of Escherichia coli RNA polymerase. | {
"entities": {
"gene": [
{
"text": "cAMP receptor protein contact site",
"start": 12,
"end": 46
},
{
"text": "Escherichia coli RNA polymerase",
"start": 71,
"end": 102
}
]
}
} | [] |
Here we show that epidermal growth factor or platelet-derived growth factor stimulation of intact human or murine cells leads to phosphorylation of Nck protein on tyrosine, serine, and threonine residues. | {
"entities": {
"gene": [
{
"text": "epidermal growth factor",
"start": 18,
"end": 41
},
{
"text": "platelet-derived growth factor",
"start": 45,
"end": 75
},
{
"text": "Nck protein",
"start": 148,
"end": 159
... | [] |
A major mechanism whereby steroid hydroxylase gene transcription is regulated in the adrenal cortex requires the pituitary peptide hormone, ACTH, which acts via cAMP. | {
"entities": {
"gene": [
{
"text": "steroid hydroxylase gene",
"start": 26,
"end": 50
},
{
"text": "ACTH",
"start": 140,
"end": 144
}
]
}
} | [] |
A combination of comparative sequence analysis and thermodynamic methods reveals the conservation of tertiary structure elements in the 5' untranslated region (UTR) of human enteroviruses and rhinoviruses. | {
"entities": {}
} | [] |
Km and Vmax for two substrates, src-related peptide and poly (Glu, Tyr) (4: 1), were 2. 4 mM and 2. 5 mumol min-1 mg-1 and 0. 26 mM and 1. 2 mumol min-1 mg-1, respectively. | {
"entities": {
"gene": [
{
"text": "src-related peptide",
"start": 32,
"end": 51
}
]
}
} | [] |
Strategies for blood screening for the hepatitis C virus and for the human immunodeficiency virus in high risk groups. | {
"entities": {}
} | [] |
Comparison of data obtained with the results of chronic treatment with the opioid antagonist permits to conclude that the chronic blockade increases the fatiguability to a great extent than chronic activation of opioid system. | {
"entities": {}
} | [] |
Laboratory studies using Ca45 labeled teeth and biologically stained teeth confirmed that the dentifrice did not decalcify enamel or bleach teeth. | {
"entities": {}
} | [] |
Structure and expression of a gene from Arabidopsis thaliana encoding a protein related to SNF1 protein kinase. | {
"entities": {
"gene": [
{
"text": "SNF1",
"start": 91,
"end": 95
}
]
}
} | [] |
We have cloned and characterized a 55-kb region of DNA surrounding HRAS1. | {
"entities": {
"gene": [
{
"text": "HRAS1",
"start": 67,
"end": 72
}
]
}
} | [] |
The ORF1 protein was found to be highly homologous to the putative potexvirus RNA replicases; ORF2,-3,-5 and-6 proteins also have analogues among the potex-and/or carlavirus-encoded proteins. | {
"entities": {
"gene": [
{
"text": "potexvirus RNA replicases",
"start": 67,
"end": 92
}
]
}
} | [] |
A total of 281 patients were divided into groups according to their clinical diagnosis and were examined using capnography, spirometry and blood-gas analysis. | {
"entities": {}
} | [] |
The relationships between the partial pressures of O2 and CO2 as well as between their gradients, become stronger with the increase of the ventilation-perfusion ratio. | {
"entities": {}
} | [] |
No significant correlations of peak VO2 were observed between the 3 tests. | {
"entities": {}
} | [] |
An RNA-binding protein gene (rbp1) from Drosophila melanogaster, encoding an RNA recognition motif and an Arg-Ser rich (RS) domain, has been characterized. | {
"entities": {
"gene": [
{
"text": "RNA-binding protein gene",
"start": 3,
"end": 27
},
{
"text": "rbp1",
"start": 29,
"end": 33
}
]
}
} | [] |
A comparative study of the total protein profiles of wild-type S. entomophila UC9 and mutant UC21 revealed that the mutant lacked an approximately 44-kDa protein and overexpressed an approximately 20-kDa protein. | {
"entities": {}
} | [] |
Characterization of the regulon controlled by the leucine-responsive regulatory protein in Escherichia coli. | {
"entities": {
"gene": [
{
"text": "leucine-responsive regulatory protein",
"start": 50,
"end": 87
}
]
}
} | [] |
Mapping of the mouse ornithine decarboxylase-related sequence family. | {
"entities": {
"gene": [
{
"text": "mouse ornithine decarboxylase-related sequence family",
"start": 15,
"end": 68
}
]
}
} | [] |
This mutation also results in markedly decreased levels of CAD mRNA and protein in the mutant. | {
"entities": {
"gene": [
{
"text": "CAD mRNA",
"start": 59,
"end": 67
}
]
}
} | [] |
Mutational studies revealed that it was the homeodomain binding site II sequence that was required for this regulation. | {
"entities": {
"gene": [
{
"text": "homeodomain binding site II sequence",
"start": 44,
"end": 80
}
]
}
} | [] |
Thus, the pol alpha-primase complex appears to act processively for only a short distance. | {
"entities": {
"gene": [
{
"text": "pol alpha",
"start": 10,
"end": 19
},
{
"text": "primase",
"start": 20,
"end": 27
}
]
}
} | [] |
Interestingly, the positions of these introns have been conserved in comparison with the genes of two other transglutaminase-like activities described in the literature, but the TGM1 gene is by far the smallest characterized to date because its introns are relatively smaller. | {
"entities": {
"gene": [
{
"text": "TGM1 gene",
"start": 178,
"end": 187
}
]
}
} | [] |
In a retrospective analysis of data from 35 cases with malignant lymphoma from a cohort of 2017 HIV-infected patients, the stage of HIV-disease, the CD4 counts at the time of diagnosis, and the use of antineoplastic agents or radiotherapy were correlated with outcome. | {
"entities": {
"gene": [
{
"text": "CD4",
"start": 149,
"end": 152
}
]
}
} | [] |
1. | {
"entities": {}
} | [] |
Effects of dioxins on thyroid function in newborn babies. | {
"entities": {}
} | [] |
cDNA clones encoding Arabidopsis thaliana and Zea mays mitochondrial chaperonin HSP60 and gene expression during seed germination and heat shock. | {
"entities": {
"gene": [
{
"text": "Zea mays mitochondrial chaperonin HSP60",
"start": 46,
"end": 85
}
]
}
} | [] |
The single site of glycosylation is located near the C-terminus in the N-glycosylation sequon-Asn-Cys-Ser-in which Cys forms part of a disulphide bridge. | {
"entities": {}
} | [] |
The pulmonary toxic events induced by acute nitrogen dioxide (NO) 2 exposure were studied in the rat to develop an inhalation model to investigate therapeutic measures. | {
"entities": {}
} | [] |
The pulmonary effects observed, became more pronounced with increasing NO2 concentrations (0, 25, 75, 125, 175 or 200 ppm, 1 ppm NO2 = 1. 88 mg m-3 NO2) and exposure times (5, 10, 20 or 30 min). | {
"entities": {}
} | [] |
Interaction of H-2Eb with an IAP retrotransposon in the A20/2J B cell lymphoma. | {
"entities": {
"gene": [
{
"text": "H-2Eb",
"start": 15,
"end": 20
},
{
"text": "IAP retrotransposon",
"start": 29,
"end": 48
}
]
}
} | [] |
Gestational trophoblastic diseases: recent advances in the understanding of cytogenetics, histopathology, and natural history. | {
"entities": {}
} | [] |
With the exception of mutants that remove the membrane anchor domain, all of the mutant glycoproteins retained the ability to cause fusion of CD4-bearing cells. | {
"entities": {
"gene": [
{
"text": "CD4",
"start": 142,
"end": 145
}
]
}
} | [] |
The subunit protein of curli was highly homologous at its amino terminus to SEF-17, the subunit protein of thin, aggregative fimbriae of Salmonella enteritidis 27655 strain 3b, suggesting that these fibres form a novel class of surface organelles on enterobacteria. | {
"entities": {
"gene": [
{
"text": "curli",
"start": 23,
"end": 28
},
{
"text": "SEF-17",
"start": 76,
"end": 82
}
]
}
} | [] |
Substitution of the DR1 beta chain with H-2E beta k led to a dramatic loss of recognition; alpha chain substitution had a less marked effect. | {
"entities": {
"gene": [
{
"text": "DR1 beta chain",
"start": 20,
"end": 34
},
{
"text": "H-2E beta k",
"start": 40,
"end": 51
}
]
}
} | [] |
This negative regulatory pathway may be important for determining cell fate or maintaining an inducible state in the ventroposterior region of the embryo. | {
"entities": {}
} | [] |
The distal portion of the rat insulin I gene 5'-flanking DNA contains two sequence elements, the Far and FLAT elements, that can function in combination, but not separately, as a beta-cell-specific transcriptional enhancer. | {
"entities": {
"gene": [
{
"text": "rat insulin I gene 5'-flanking DNA",
"start": 26,
"end": 60
}
]
}
} | [] |
The deduced amino acid sequence exhibited 98% identity to the human cellular transglutaminase sequence. | {
"entities": {}
} | [] |
Repeated efforts to isolate recombinant baculoviruses containing a wild-type kinase failed, whereas recombinants expressing a nonfunctional kinase with a catalytic domain II mutation were readily isolated. | {
"entities": {}
} | [] |
Finally, we determined that the P68 amino terminus was both necessary and sufficient for binding dsRNA as we were able to transfer dsRNA-binding properties to a reporter gene product previously unable to bind RNA. | {
"entities": {
"gene": [
{
"text": "P68",
"start": 32,
"end": 35
}
]
}
} | [] |
From August 1989 to October 1990, 83 pregnant Chinese women were the subjects for measuring the levels of plasma functional antithrombin III (AT III) activity. | {
"entities": {
"gene": [
{
"text": "antithrombin III",
"start": 124,
"end": 140
},
{
"text": "AT III",
"start": 142,
"end": 148
}
]
}
} | [] |
Visual acuity may be decreased by transient changes in refractive error caused by sulfonamides, the antifungal agent metronidazole, thiazide diuretics, and carbonic anhydrase inhibitors. | {
"entities": {
"gene": [
{
"text": "carbonic anhydrase",
"start": 156,
"end": 174
}
]
}
} | [] |
Currents aspects of H2 receptor antagonists in the treatment of ulcers | {
"entities": {
"gene": [
{
"text": "H2 receptor",
"start": 20,
"end": 31
}
]
}
} | [] |
In addition, a 21-mer subrepeat structure is also present in each unit. | {
"entities": {}
} | [] |
Sequencing revealed one large open reading frame encoding a 39-kDa protein. | {
"entities": {}
} | [] |
These sites are also potential keratan sulfate attachment sites. | {
"entities": {}
} | [] |
We propose that plasmids of the pLS1 family (pE194, pADB201, and pLB4) share functional and structural characteristics for the regulation of their copy numbers. | {
"entities": {}
} | [] |
Perturbation of dNTP pools also affected the frameshift fidelity of the replicative yeast DNA polymerase alpha. | {
"entities": {
"gene": [
{
"text": "yeast DNA polymerase alpha",
"start": 84,
"end": 110
}
]
}
} | [] |
Differential expression of the " B " subunit of the vacuolar H (+)-ATPase in bovine tissues. | {
"entities": {
"gene": [
{
"text": "vacuolar H (+)-ATPase",
"start": 52,
"end": 73
}
]
}
} | [] |
In addition, the hGCSFR gene was chromosomally localized by Southern blot analysis of its segregation pattern in a panel of rodent-human hybrid DNAs using the radiolabeled cDNA probe. | {
"entities": {
"gene": [
{
"text": "hGCSFR gene",
"start": 17,
"end": 28
}
]
}
} | [] |
We have isolated and characterised a differentially-regulated gene family in the protozoan parasite Leishmania major. | {
"entities": {}
} | [] |
At some sites,% T is greatly increased by Cl-concentrations up to 1 M, while at other sites% T is reduced or unaffected by these conditions. | {
"entities": {}
} | [] |
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