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Selected topics in pediatric ultrasonography--1992.
{ "entities": {} }
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Methods included 24-hour dietary recall, menu weights, and recipe analysis.
{ "entities": {} }
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Factors associated with afterdrop included age, end-of-surgery temperature (both positively) and body mass (negatively).
{ "entities": {} }
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Both GH deficiency and impaired spinal growth may result in short stature, whereas the occurrence of early puberty in association with GH deficiency reduces the time available for GH therapy.
{ "entities": { "gene": [ { "text": "GH", "start": 5, "end": 7 }, { "text": "GH", "start": 135, "end": 137 }, { "text": "GH", "start": 180, "end": 182 } ] } }
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By contrast, d (T2AG3T) and d (T2G4T) form only the G-quadruplex monomer structures independent of K cation concentration as reported previously [Sen, D., & Gilbert, W.
{ "entities": { "gene": [ { "text": "d (T2AG3T)", "start": 13, "end": 23 }, { "text": "d (T2G4T)", "start": 28, "end": 37 } ] } }
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Differentiating among renal stones.
{ "entities": {} }
[]
IFI 16 mRNA was found to be constitutively expressed in lymphoid cells and in cell lines of both the T and B lineages.
{ "entities": { "gene": [ { "text": "IFI 16 mRNA", "start": 0, "end": 11 } ] } }
[]
Mitochondria-lytic action of warfarin in lymphocytes.
{ "entities": {} }
[]
Exon-intron junctions in the human and rat AdoMet decarboxylase genes were in identical positions except that exons 6 and 7 of the human gene formed a single exon in the rat gene.
{ "entities": { "gene": [ { "text": "rat AdoMet decarboxylase genes", "start": 39, "end": 69 } ] } }
[]
Interferon-alpha-induced gene expression: evidence for a selective effect of ouabain on activation of the ISGF3 transcription complex.
{ "entities": { "gene": [ { "text": "Interferon-alpha", "start": 0, "end": 16 }, { "text": "ISGF3 transcription complex", "start": 106, "end": 133 } ] } }
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Moreover, LD50 in mice of RP-170 (4. 3 g/kg on i. v.) was increased to 5. 2 g/kg by oral administration.
{ "entities": {} }
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Among the few proteins of the eukaryotic nucleolus that have been characterized, four proteins, nucleolin, fibrillarin, SSB1 and NSR1, possess a common structural motif, the GAR domain, which is rich in glycine and arginine residues.
{ "entities": { "gene": [ { "text": "nucleolin", "start": 96, "end": 105 }, { "text": "fibrillarin", "start": 107, "end": 118 }, { "text": "SSB1", "start": 120, "end": 124 }, { "text": "NSR1",...
[]
Thus, this study provides evidence that a novel, ubiquitous factor (HF-1a) and a muscle factor (HF-1b/MEF-2) can form a novel, E-box-independent pathway for muscle-specific expression in ventricular cardiac muscle cells.
{ "entities": { "gene": [ { "text": "HF-1a", "start": 68, "end": 73 }, { "text": "HF-1b", "start": 96, "end": 101 }, { "text": "MEF-2", "start": 102, "end": 107 } ] } }
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Mutations in either gene block some crucial late step in assembly of F1, causing the alpha and beta subunits to accumulate in mitochondria as inactive aggregates (Ackerman, S.
{ "entities": { "gene": [ { "text": "F1", "start": 69, "end": 71 } ] } }
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Expense limits the use of hepatitis B vaccines, but low-dose intradermal immunization has been evaluated as a cost-saving strategy in numerous studies.
{ "entities": {} }
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Estrogen replacement therapy and risk of breast cancer: results of two meta-analyses.
{ "entities": {} }
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Switching FDC-P1/MAC cells from growth in M-CSF to GM-CSF caused the selective degradation of c-fms mRNA within 6 h after factor switching.
{ "entities": { "gene": [ { "text": "M-CSF", "start": 42, "end": 47 }, { "text": "GM-CSF", "start": 51, "end": 57 }, { "text": "c-fms mRNA", "start": 94, "end": 104 } ] } }
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There was however, no significant difference in the prevalence of chronic respiratory symptoms between animal food workers with positive and negative skin tests to house dust or to fish flour or among those with increased or normal IgE (except for dyspnea).
{ "entities": { "gene": [ { "text": "IgE", "start": 232, "end": 235 } ] } }
[]
An unexpected finding was the presence at position-403 to-385 of a putative dioxin responsive element, a sequence found to be responsible for the induction of transcription of the cytochrome P450IA1 gene (CYPIA1) and other genes involved in detoxification/activation of polycyclic aromatic hydrocarbons.
{ "entities": { "gene": [ { "text": "cytochrome P450IA1 gene", "start": 180, "end": 203 }, { "text": "CYPIA1", "start": 205, "end": 211 } ] } }
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Using bovine and murine c-myb clones, no change in the rate of c-myb gene transcription or mRNA stability was detected during the cell cycle.
{ "entities": { "gene": [ { "text": "bovine and murine c-myb", "start": 6, "end": 29 }, { "text": "c-myb gene", "start": 63, "end": 73 } ] } }
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A 13 base-pair oligonucleotide spanning nucleotides + 80 to + 92 of the 5 S RNA gene retained specific and high-affinity binding, although the latter was reduced sixfold relative to longer DNA fragments.
{ "entities": { "gene": [ { "text": "5 S RNA gene", "start": 72, "end": 84 } ] } }
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Moreover, the reconstitution of eUSF and TFIID-depleted transcription complexes with purified protein fractions demonstrate that not only TFIID but also eUSF essentially participates in complex formation even on H5 promoter mutations lacking the TATA-box.
{ "entities": { "gene": [ { "text": "eUSF", "start": 32, "end": 36 }, { "text": "TFIID", "start": 41, "end": 46 }, { "text": "TFIID", "start": 138, "end": 143 }, { "text": "eUSF", "sta...
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Radiolabelled palmitate was not incorporated into the mutated protein, showing that lipid modification occurs at the Cys-22 residue.
{ "entities": {} }
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17 volunteer deaf Ss were compared with 18 volunteer hearing Ss on the Stanford Hypnotic Clinical Scale (SHCS) of Morgan and J.
{ "entities": {} }
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Mature tobacco L12 protein has 44% amino acid identity with ribosomal protein L7/L12 of Escherichia coli.
{ "entities": { "gene": [ { "text": "Mature tobacco L12 protein", "start": 0, "end": 26 }, { "text": "L7", "start": 78, "end": 80 }, { "text": "L12", "start": 81, "end": 84 } ] } }
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Nuclear-encoded chloroplast ribosomal protein L12 of Nicotiana tabacum: characterization of mature protein and isolation and sequence analysis of cDNA clones encoding its cytoplasmic precursor.
{ "entities": { "gene": [ { "text": "Nuclear-encoded chloroplast ribosomal protein L12 of Nicotiana tabacum", "start": 0, "end": 70 } ] } }
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The gene encoding IFN-gamma was previously found to contain an intronic enhancer element that was not tissue-specific in its activity, despite the restricted expression of the intact IFN-gamma-encoding gene.
{ "entities": { "gene": [ { "text": "IFN-gamma", "start": 18, "end": 27 }, { "text": "IFN-gamma-encoding gene", "start": 183, "end": 206 } ] } }
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Molecular cloning of the polypeptide component of the Rel-related human p75 nucleoprotein complex has revealed its identity with the 65-kDa (p65) subunit of NF-kappa B.
{ "entities": { "gene": [ { "text": "Rel-related human p75 nucleoprotein complex", "start": 54, "end": 97 }, { "text": "p65", "start": 141, "end": 144 }, { "text": "NF-kappa B", "start": 157, "end": 167 } ...
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Of the drugs orally administered, WR-168643 was the best protector with a DMF of 1. 51.
{ "entities": {} }
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Characterization of these R subunits by their 8-azido-cAMP photoaffinity labeling and immunoreactivity, as well as by a phosphorylation-dependent mobility shift on sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), indicated subunit sizes of RII beta (53 kDa) greater than RII alpha dephosphoform (51 ...
{ "entities": { "gene": [ { "text": "RII beta", "start": 261, "end": 269 }, { "text": "RII alpha", "start": 292, "end": 301 }, { "text": "RI alpha", "start": 338, "end": 346 } ] } }
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Comparison of the genomic DNA sequence with that of the four different mRNAs indicates that these transcripts are produced by alternative splicing of the murine pre-mRNA according to a cassette model.
{ "entities": {} }
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During the 1980' s, quantifications of immunoserological testings, especially C reactive protein, rheumatoid factor and antistreptolysin O, progressed rapidly.
{ "entities": { "gene": [ { "text": "C reactive protein", "start": 78, "end": 96 }, { "text": "rheumatoid factor", "start": 98, "end": 115 }, { "text": "antistreptolysin O", "start": 120, "end": 138 } ]...
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Within the human enhancer, these two sites are located within the previously defined DNase I footprints, NFAT-1 and NFIL-2B, respectively.
{ "entities": { "gene": [ { "text": "DNase I footprints", "start": 85, "end": 103 }, { "text": "NFAT-1", "start": 105, "end": 111 }, { "text": "NFIL-2B", "start": 116, "end": 123 } ] } }
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The cardiac myosin light chain-2 (MLC-2) gene promoter contains several positive and negative cis-acting sequences that are involved in the regulation of its expression.
{ "entities": { "gene": [ { "text": "cardiac myosin light chain-2", "start": 4, "end": 32 }, { "text": "MLC-2", "start": 34, "end": 39 } ] } }
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Deletion mutagenesis demonstrated that these two elements are involved in the positive regulation of MLC-2 gene transcription.
{ "entities": { "gene": [ { "text": "MLC-2 gene", "start": 101, "end": 111 } ] } }
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Disruption mutations have been constructed in the SLK1 gene. slk1 null mutants cannot grow at 37 degrees C, but many cells can grow at 30, 24, and 17 degrees C.
{ "entities": { "gene": [ { "text": "SLK1 gene", "start": 50, "end": 59 }, { "text": "slk1 null mutants", "start": 61, "end": 78 } ] } }
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Molecular and genetic analysis of the yeast early meiotic recombination genes REC102 and REC107/MER2.
{ "entities": { "gene": [ { "text": "yeast early meiotic recombination genes REC102", "start": 38, "end": 84 }, { "text": "REC107", "start": 89, "end": 95 }, { "text": "MER2", "start": 96, "end": 100 } ...
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Probable progressive multifocal leukoencephalopathy (PML) was diagnosed on the basis of clinical picture and magnetic resonance imaging in a 63-year-old man with a complete remission of a non-Hodgkin' s lymphoma.
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Proprotein processing occurs intracellularly.
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A 32P-labeled LAP DNA-binding and dimerization domain " zipper probe " was used to isolate a clone that encodes a new C/EBP-homologous protein: CHOP-10.
{ "entities": { "gene": [ { "text": "LAP", "start": 14, "end": 17 }, { "text": "C/EBP-homologous protein", "start": 118, "end": 142 }, { "text": "CHOP-10", "start": 144, "end": 151 } ] } }
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Using a degenerate oligodeoxyribonucleotide (oligo) based on the N-terminal aa sequence, plus an internal oligo homologous to a conserved region within the portion of CYP1 and CYP2 that had been deleted in the genome, a CYP3-specific DNA fragment was generated by the polymerase chain reaction (PCR) using GL81 genomic D...
{ "entities": { "gene": [ { "text": "CYP1", "start": 167, "end": 171 }, { "text": "CYP2", "start": 176, "end": 180 }, { "text": "CYP3-specific DNA fragment", "start": 220, "end": 246 } ] } }
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Stringent hybridization of EHS-1 back to primate genomic DNA indicates two distinct EHS-1 loci in normal human DNA, an identical band pattern in chimpanzee DNA, and a single locus in rhesus monkey DNA.
{ "entities": { "gene": [ { "text": "EHS-1", "start": 27, "end": 32 }, { "text": "EHS-1 loci", "start": 84, "end": 94 } ] } }
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The level of carboxyl-terminal parathyroid hormone in the patients with thyroid carcinoma was higher than that in the patients without thyroid carcinoma (P less than 0. 05).
{ "entities": { "gene": [ { "text": "carboxyl-terminal parathyroid hormone", "start": 13, "end": 50 } ] } }
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The Caenorhabditis elegans vitellogenin genes are subject to sex-, stage-, and tissue-specific regulation: they are expressed solely in the adult hermaphrodite intestine.
{ "entities": { "gene": [ { "text": "Caenorhabditis elegans vitellogenin genes", "start": 4, "end": 45 } ] } }
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The functions of isolated portions of the insulin, IAPP, and beta GK promoters were studied by using transient expression and DNA binding assays.
{ "entities": { "gene": [ { "text": "insulin", "start": 42, "end": 49 }, { "text": "IAPP", "start": 51, "end": 55 }, { "text": "beta GK promoters", "start": 61, "end": 78 } ] } }
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The c-Ets-1 oncoprotein is a transcription activator that specifically binds to DNA.
{ "entities": { "gene": [ { "text": "c-Ets-1 oncoprotein", "start": 4, "end": 23 } ] } }
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Previous transactivation experiments indicated that three amino acids residing in this region, Gly, Ser and Val, appear to be critical for target-site discrimination.
{ "entities": {} }
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GR63178A is a water-soluble analogue of mitoquidone, a pentacyclic pyrroloquinone.
{ "entities": {} }
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Marker rescue analysis has localized ts8 to a 910-bp internal segment of rpoB that encodes the Rif domain.
{ "entities": { "gene": [ { "text": "ts8", "start": 37, "end": 40 }, { "text": "rpoB", "start": 73, "end": 77 }, { "text": "Rif domain", "start": 95, "end": 105 } ] } }
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This vector transfected into the yeast Saccharomyces cerevisiae directs expression of a secreted mature protein at levels up to 200 mg of LAPP/liter of culture medium.
{ "entities": {} }
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Competition analysis by gel mobility shift electrophoresis indicates that this DNA-protein interaction is novel and not related to many transcription factors previously reported.
{ "entities": {} }
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This DNA motif represents a novel protein-binding sequence.
{ "entities": {} }
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OBJECTIVE: The study was designed to investigate the frequency of alterations in serum creatinine in patients with psoriasis receiving 5 mg/kg/day of cyclosporine.
{ "entities": {} }
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Intrapocket chemotherapy in adult periodontitis using a new controlled-release insert containing ofloxacin (PT-01).
{ "entities": {} }
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Electromagnetic blood flow (BF) probe was applied on the left anterior descending artery (LAD).
{ "entities": {} }
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Hence temperature and virF are both required for the induction of the yop regulon.
{ "entities": { "gene": [ { "text": "virF", "start": 22, "end": 26 }, { "text": "yop regulon", "start": 70, "end": 81 } ] } }
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Problems remain to be resolved in the area of quantitative risk assessment.
{ "entities": {} }
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The Klebsiella aerogenes gene maoA, which is involved in the synthesis of monoamine oxidase, was induced by tyramine and the related compounds, subjected to catabolite and ammonium ion repression, and cloned.
{ "entities": { "gene": [ { "text": "Klebsiella aerogenes gene maoA", "start": 4, "end": 34 }, { "text": "monoamine oxidase", "start": 74, "end": 91 } ] } }
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Eight of 14 infectious or inflammatory lesions could be detected in the early scan (4-6 h p. i.).
{ "entities": {} }
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Similar observations have been made previously for other genes.
{ "entities": {} }
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Preceptorship of CNS students: an exploratory study.
{ "entities": {} }
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To determine the genetic basis for the differences between the cardiac and brain AE3 variants, we isolated and characterized the rat gene.
{ "entities": { "gene": [ { "text": "brain AE3 variants", "start": 75, "end": 93 } ] } }
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The 1. 7 kb cloned fragment was sequenced and shown to contain the entire fliA gene.
{ "entities": { "gene": [ { "text": "fliA gene", "start": 74, "end": 83 } ] } }
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Institution of both intravenous and intracisternal administration of amphotericin B and possibly concomitant intravenous administration of dexamethasone may be warranted in situations in which the association of C. immitis with CNS vasculitis or encephalitis appears likely before serologic or cultural confirmation of C...
{ "entities": {} }
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Lac operators were introduced into several positions within the CAB promoter and operator-free plasmid was used as control.
{ "entities": { "gene": [ { "text": "Lac", "start": 0, "end": 3 }, { "text": "CAB promoter", "start": 64, "end": 76 } ] } }
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Overproduction, purification and characterization of M. HinfI methyltransferase and its deletion mutant.
{ "entities": { "gene": [ { "text": "M. HinfI methyltransferase", "start": 53, "end": 79 } ] } }
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Various companies produce this type of lens.
{ "entities": {} }
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From March 5 through October 26, 1991, eight persons were diagnosed with elevated blood lead levels (BLLs) at a local hospital and were reported to the notifiable disease surveillance system maintained by the Alabama Department of Public Health (ADPH).
{ "entities": {} }
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According to the changes of perfusion defects between Ex, RD and ReI images, they were classified into 3 types: Type I; perfusion defect on the RD image was identical to ReI image (75%) Type I was divided into 2 subgroups whether perfusion defect at Ex was unchanged (Ia, 42%) or improved (Ib, 33%) on the RD image.
{ "entities": {} }
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Keck, C. J.
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Twenty-eight (7. 0%) infants without periventricular hemorrhage were revealed as having spastic cerebral palsy by neurodevelopmental evaluation in later infancy.
{ "entities": {} }
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A possible mechanism is that elevated alveolar pressure and decreased cardiac output eliminate blood flow from corner vessels in nondependent high VA/Q regions.
{ "entities": {} }
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In both cities, HTLV-I/II prevalence increased significantly with age, and the New Orleans age-and sex-adjusted HTLV-I/II prevalence was significantly higher than that of Baltimore (P less than. 001).
{ "entities": {} }
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Hybridization data indicate that 6F6. 2 corresponds to the previously characterized m6F6 cDNA clone and that 6F6. 1 and 6F6. 3, but not 6F6. 2, are adjacent to alpha-type genes.
{ "entities": { "gene": [ { "text": "6F6. 2", "start": 33, "end": 39 }, { "text": "m6F6 cDNA clone", "start": 84, "end": 99 }, { "text": "6F6. 1", "start": 109, "end": 115 }, { "text": "6F6. 3...
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The SEN1 gene corresponds to a 6, 336-bp open reading frame coding for a 2, 112-amino-acid protein (molecular mass, 239 kDa).
{ "entities": { "gene": [ { "text": "SEN1 gene", "start": 4, "end": 13 } ] } }
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Protein tyrosine kinases (PTKs) are implicated in the control of cell growth by virtue of their frequent appearance as products of retroviral oncogenes, as intracellular signal transducers, and as growth factor receptors or components thereof.
{ "entities": { "gene": [ { "text": "Protein tyrosine kinases", "start": 0, "end": 24 }, { "text": "PTKs", "start": 26, "end": 30 }, { "text": "growth factor receptors", "start": 197, "end": 220 } ] }...
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The IA4 mAb was identified among a series of antibodies raised in BALB/c mice after immunization against a HLA class I-deficient, lymphokine-activated killer (LAK)-susceptible EBV-B lymphocyte line.
{ "entities": { "gene": [ { "text": "IA4 mAb", "start": 4, "end": 11 }, { "text": "HLA", "start": 107, "end": 110 } ] } }
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In a randomized double-blind cross-over study, the subjects received theophylline 5 mg. kg-1 per day with omeprazole 20 mg per day or identical placebo during two periods, each of 7 days, separated by a washout period of 7 days.
{ "entities": {} }
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Primer extension and mung bean and S1 nuclease mapping indicated multiple transcription initiation sites and were consistent with Northern analyses.
{ "entities": { "gene": [ { "text": "mung bean and S1 nuclease", "start": 21, "end": 46 } ] } }
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Two variant PRP-precursor alleles occur which slightly differ in the number of repeats in domain C.
{ "entities": { "gene": [ { "text": "PRP-precursor alleles", "start": 12, "end": 33 } ] } }
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Unlike the typical enhancer element, this region functions in an orientation-dependent manner.
{ "entities": {} }
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Allagille' s syndrome associated with antenatal ascites
{ "entities": {} }
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Sensitivity and specificity was established for the Pharmacia CAP System and the DPC AlaSTAT System by comparison with results of the skin prick test.
{ "entities": {} }
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PSI-G and PSI-K probably have evolved from a gene duplication of an ancestral gene.
{ "entities": { "gene": [ { "text": "PSI-G", "start": 0, "end": 5 }, { "text": "PSI-K", "start": 10, "end": 15 } ] } }
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Site-directed mutagenesis revealed that two clusters of basic amino acids within a conserved basic region and two amphipathic helices within the adjacent HLH domain are essential for sequence-specific DNA binding and hetero-oligomerization, respectively.
{ "entities": {} }
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Dimerization of Myf-5 with the ubiquitously expressed bHLH protein E12 not only increases the affinity for DNA but also stimulates transactivation independently of DNA binding.
{ "entities": { "gene": [ { "text": "Myf-5", "start": 16, "end": 21 }, { "text": "E12", "start": 67, "end": 70 } ] } }
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SEA was recorded with bidirectional filters at 25-250 HZ and 40-250 Hz using Simson method.
{ "entities": {} }
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Neural-specific expression, genomic structure, and chromosomal localization of the gene encoding the zinc-finger transcription factor NGFI-C.
{ "entities": { "gene": [ { "text": "zinc-finger transcription factor NGFI-C", "start": 101, "end": 140 } ] } }
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An experiment examined the effects of treatment with gonadotrophin releasing hormone (100 micrograms GnRH injected 24 h after progestagen sponge removal), season of treatment (autumn v. spring), the effect of supplementary feeding with lupin grain (in autumn only, from 12 days before until 8 days after sponge removal) ...
{ "entities": { "gene": [ { "text": "gonadotrophin releasing hormone", "start": 53, "end": 84 }, { "text": "GnRH", "start": 101, "end": 105 }, { "text": "pregnant mare serum gonadotrophin", "start": 417, "end": 4...
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Drug-drug interactions are most likely to occur in patients receiving multiple medications and with drugs that have a narrow therapeutic window.
{ "entities": {} }
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Total body irradiation was delivered according to a hyperfractionated scheme of 12 fractions given three per day 5 hr apart for 4 days.
{ "entities": {} }
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A reduction in blood pressure was only observed at the end of the study, from 142 +/-17/86. 6 +/-9. 1 to 139 +/-13/82. 9 +/-8. 9 mmHg (P less than 0. 05 for DBP).
{ "entities": {} }
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A gene homologous to the Escherichia coli dnaA gene was isolated from Pseudomonas putida and its transcription was investigated in E. coli as well as in P. putida.
{ "entities": { "gene": [ { "text": "Escherichia coli dnaA gene", "start": 25, "end": 51 } ] } }
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STP1 is an unessential yeast gene involved in the removal of intervening sequences from some, but not all, families of intervening sequence-containing pre-tRNAs.
{ "entities": { "gene": [ { "text": "STP1", "start": 0, "end": 4 } ] } }
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Using these antibodies, we were able to define the conditions to completely solubilize the Cdc25 protein.
{ "entities": { "gene": [ { "text": "Cdc25 protein", "start": 91, "end": 104 } ] } }
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GCR1 gene function is required for high-level glycolytic gene expression in Saccharomyces cerevisiae.
{ "entities": { "gene": [ { "text": "GCR1 gene", "start": 0, "end": 9 } ] } }
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The decay curves of chlorophyll fluorescence showed a superposition of three exponentially decaying components with time constants of T1 = 100-200 ps, T2 = 300-500 ps and T3 = 2. 0-3. 5 ns.
{ "entities": {} }
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After tilting, systolic blood pressure fell an average of 17% in patients who cramped infrequently (p = 0. 0031) but only 10% in frequently cramping patients.
{ "entities": {} }
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Most apneic events occurred during Stages I and II, and REM, but this proportion was less during the gamma OH study (77. 9 +/-8. 9%) than during the control studies (92. 3 +/-1. 9 and 95. 9 +/-2. 2%), apneas occurring even during SWS with gamma OH. (ABSTRACT TRUNCATED AT 250 WORDS)
{ "entities": {} }
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Eight rabbits were exposed to 0. 7 +/-0. 4 mg/m3 Co2 + as CoCl2 and 1. 2 +/-0. 7 mg/m3 Cr3 + as Cr (NO3) 3 (group Co + Cr), eight to 0. 6 +/-0. 5 mg/m3 Co2 + (group Co), and eight to filtered air (control group), for 4 months, 5 days/week, and 6 hr/day.
{ "entities": {} }
[]