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All are good prognostic factors for neuroblastoma except
The expression of specific neurotrophin receptors like TrkA are good prognostic factors for Neuroblastoma whereas expression of TrkB like neurotrophin receptors worsens the disease. Refer robbins 9/e 260p
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A 23-year-old man presents with prolonged nose bleeds. He has always noted easy bruising, and ongoing bleeding after minor cuts. There is no prior history of surgery or dental procedures. His hemoglobin is 14.5 g/dL, platelets 200,000/mL, and PT/PPT is normal. Further testing reveals that the bleeding time is elevated;...
von Willebrand's disease is the most common inherited bleeding disorder. The abnormal plasma glycoprotein, von Willebrand factor (vWF), has two major functions: facilitating platelet adhesion and serving as a carrier for factor VIII. The disease is heterogeneous in its manifestations but can be very severe (type III di...
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Diabetes control is best monitored by -
Measurement of glycated hemoglobin (HbA1c) is the standard method for assessing long-term glycemic control. When plasma glucose is consistently elevated, there is an increase in nonenzymatic glycation of hemoglobin. This alteration reflects the glycemic history over the previous 2-3 months, because erythrocytes have an...
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A male patient was undergoing routine health checkup and investigations when a lump was incidentally diagnosed on clinical examination. Clinician advised USG following which USG guided biopsy was done. HPE examination revealed the following diagnosis. Patient was staed on chemotherapy including a drug obtained from the...
Vinblastine is an alkaloid derived from the periwinkle plant Vinca rosea. It has clinical activity in the treatment of Hodgkin's and non-Hodgkin's lymphomas, breast cancer, and germ cell cancer. It inhibits mitosis that is M phase of cell cycle.
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Substrate level phosphorylation in Glycosis is seen in which step?
Conversion of Phosphoenol Pyruvate to Pyruvate Phosphoenolpyruvate is conveed to 'Enol' pyruvate, the reaction is catalyzed by the enzyme Pyruvate kinase. The high energy PO4 of phosphoenolpyruvate is directly transferred to ADP producing ATP (Refer box). Note Reaction is irreversible.ATP is formed at the substrate lev...
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If blood gas analysis reveal pH = 7.52, pCO = 30 ; pO2 = 105. This will be compensated by ?
First step Determine whether it is acidosis or alkalosis Increase in pH suggests alkalosis Second step Look at CO2 or HCO3- to determine the cause Decreased PCO2 suggests respiratory alkalosis Respiratory alkalosis Respiratory alkalosis occurs because CO2 is blown off in excess equation shifts to left and H+ conc. dec...
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Which of the following is false about the Valves of Houston
A i.e. Disappear on distensionGastric rugae of stomach, and longitudinal folds in mucosa of upper rectum and colon are temporary mucosal folds and are obliterated by distension. Whereas , plica circularis (valves of kerkring) of small intestine, crescentic mucosal folds of cystic duct ( spiral valve of Heister), transv...
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Which of the following local anaesthetic causes least vasodilation:
Prilocaine causes less vasodilation than other local anesthetics and thus used without using epinephrine added to the local anesthetic solution.
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A patient underwent thyroidectomy for Hyperthyroidism. Two days later he presented with features of thyroid storm. What is the most likely cause?(AIIMS November 2015. COMED K 2007)
Ans. d. Inadequate preoperative preparation (Ref: Schwartz 9/e p1355: Sabiston 19/e p897; Bailey 26/e p762, 25/e p786- 787; Harrison 18/e p2927)Thyrotoxic crisis (storm) is an acute exacerbation of hyperthyroidism. It occurs if a thyrotoxic patient has been inadequately prepared for thyroidectomy."Thyrotoxic crisis (st...
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Cell wall of bacillus anthracis is composed of -
Ans. is 'a' i.e., Peptidoglycan The layer just outside the bacterial cytoplasmic membrane is the peptidoglycan layer or cell wall.It is present in both gram-positive and gram negative organisms.The peptidoglycan layer of gram positive bacteria is thick and contain teichoic acid, while in gram negative bacteria it is th...
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Best parameter to monitor the response to injection of a bolus dose of fluids in a dehydrated child is
Signs of mild or moderate dehydration include: Thirst ,Dry or sticky mouth. Signs of severe dehydration include: Not peeing or having very dark yellow pee. Very dry skin. Feeling dizzy. Rapid heabeat. Rapid breathing. Sunken eyes. Sleepiness, lack of energy, confusion or irritability. Fainting. Reference: GHAI Essentia...
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A decrease in cerebral blood flow to zero causes death of brain tissue within
(A) 4-10 minutes # Decrease in cerebral blood flow to zero causes death of brain tissue within 4-10 minutes;> Values <16-18 mL/100 g tissue per minute cause infarction within an hour; and> Values <20 mL/100 g tissue per minute cause ischemia without infarction unless prolonged for several hours or days.> If blood flow ...
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What is the recommended lifespan of Cu T 380A is?
The recommended lifespan of various Cu T devices are as follows: Cu T 380A - 10 years Cu T 380Ag - 4 years Cu T 200 - 4 years Nova Cu T 200 - 5 years Cu T 220C - 3 years Multiload Cu T 250 - 3 years Multiload Cu T 375 - 5 years Ref: Comp Textbook of Obstetrics and Gynecology, Sadhana Gupta, 2011, Page 308
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Which of the drug's main action is increasing uveo-scleral outflow
Ref: HL Sharma 3rd ed pg no:140 DOC for chronic glaucoma is latanoprost- PGF2 alpha analog It acts by increasing uveoscleral outflow of aqueous humor
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TPN is indicated in all except
Ans. (c) SepsisRef Bailey and Love 27th edition Page 287; Surgery Sixer 3rd Edition Page 5* Indication of parenteral nutrition in 'sepsis' is under intensive study but not proven so far to be effective, however in the above options it is the best Choice.
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Vertebra plana seen in -a) Eosinophilia granulomab) Traumac) Paget's diseased) Malignancye) Ewing's sarcoma
Vertebra plana This term is used to describe uniform collapse of a vertebral body into a thin, flat disc. The most common cause is eosinophilic granuloma, with the thoracic vertebrae most frequently affected. Causes are :- Histocytosis - X (Eosinophilic granuloma) Leukemia TB Metastasis, Multiple myeloma, Ewing's s...
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Which is the most common site for berry aneurysm in circle of willis is seen at bifurcation between
Ans. is 'a' i.e., Anterior communicating artery and anterior cerebral artery AZX
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BCG is
Ans. a (Live attenuated vaccine). (Ref. Park, PSM, 17th ed., 148)VACCINESLive attenuated vaccinesInactivated or killed vaccines1.BCG1.Typhoid2.Typhoid oral2.Cholera3.Plague3.Pertussis4.Mumps4.C.S. Meningitis5.Measles5.Plague6.Rubella6.Rabies7.Yellow fever7.Influenza8.OPV8.KFD vaccine9.Influenza9.Salk (Polio)10.Epi. typ...
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A 50-year-old construction worker continues to have elevated BP of 160/100 mmHg after a third agent (thiazide) is added to his anti-hypeensive regimen. Physical examination is normal, electrolytes are normal and he is not taking any over the counter medications. Which is the next helpful step in the diagnosis of this p...
The patient is suffering from resistant hypeension and the leading cause of resistant hypeension is non- compliance on the pa of patient. Resistant hypeension is defined as blood pressure that remains above goal in spite of the concurrent use of 3 antihypeensive agents of different classes. Ideally, one of the 3 agents...
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A 50-year-old know asthmatic develops sudden onset right-sided chest pain with dyspnea. Chest X-ray reveals hyperlucency on right side with shift of trachea to left side. The best option of treatment for immediate relief of symptoms is
Patient might have developed pneumothorax , Pathophysiology Airway hyper-reactivity (AHR) - the tendency for airways to narrow excessively in response to triggers that have little or no effect in normal individuals - is integral to the diagnosis of asthma and appears to be related, although not exclusively, to airway i...
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NOT a content of middle mediastinum:
The esophagus is considered to be located in the superior and posterior mediastinum.
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Leucine zipper complex is
Proteins that bind to DNA contain a limited number of motifs.The helix-loop-helix motif is an example found in a number of proteins that function in a number of proteins that function as transcription factors Example: zinc fingers, and leucine zippers . REF :LIPPINCOTT'S TEXTBOOK OF BICHEMISTRY ;8th EDITION ;Page no :1...
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A 6 yr. old boy presents with small hypopigmented scaly macules on cheek. Some of his friends also have similar lesions. Most probable diagnosis is?
Ans. D. Pityriasis alba* Occurs predominantly in children between the ages of 3 and 16 years, the sexes are equally susceptible.* The individual lesion is a rounded, oval or irregular plaque, which is red, pink or skin-colored and has fine lamellar or branny scaling. Initially, the erythema may be conspicuous and there...
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Hypotony maculopathy, which of the following is not a cause?
Suprachoroidal Hemorrhage is not a cause of hypotony maculopathy. Hypotony maculopathy is low IOP associated with chorioretinal folds near macula, optic nerve head edema and vessel touosity. Causes Postoperative Hypotony Mitomycin C (MMC) toxicity of the ciliary body Overfiltering Bleb Wound Leak Traumatic Hypotony Scl...
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Stage of falciparum not seen in PBS is -
P.falciparum Forms in peripheral blood-ring forms and gametocytes (crescent shaped) A) Most pathogenic B). No relapses in P.falciparum-exo-erythrocytic schizogony is absent C). Complications-pernicious malaria,black water fever D)pernicious malaria-1). Cerebral malaria-hyperpyrexia, coma,paralysis.Brain is congested.Ca...
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Austenite is an alloy of iron and carbon with the iron in:
At room temperature, pure iron has a body-centered-cubic (bcc) structure. This phase is stable up to 912 °C, where it transforms to a face-centered-cubic (fcc) structure. The solubility of carbon in bcc is very low and reaches a maximum of  0.02% at 723°C. This material is known as ferrite.   Above 723 °C, a solid solu...
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Antihypertensive of choice in pregnancy is:
Ref: Dana Textbook of Obstetrics, 5th ed pg 506 Explanation: See the following table Antihypertensives Used in Pregnancy MOA Side effects Remarks Methyl dopa Centrally acting anti-adrenergic * Drowsiness * Headache * Postnatal depression * Postural hypotension * Liver dysfunction * Leukopenia * Hemolytic anemia Contrai...
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True about formalin
Formalin is not used as preservative for chemical analysis because extraction of poison becomes difficult. PRESERVATIVES : 1. Saturated solution of NaCl - commonly used 2. Rectified spirit (95% alcohol )- Best preservative 3. 10% Formalin - for histopathological examination 4. 50% Glycerol - for virology 5. NaF - For C...
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A newborn child is noted to have a bulky abdominal tumor. CT scans reveal that the mass involves the right abdomen and retroperitoneum. The tumor is resected, revealing ganglion cells and primitive, small, round cells occasionally organized in rosettes, embedded in a fibrillary pink matrix. Special studies confirm the ...
Neuroblastoma is a childhood tumor of the sympathetic nerves, which most commonly arises along the paraveebral chain or within the adrenal medulla. Neuroblastoma has two characteristic genetic markers: a 1p deletion and an N-myc translocation. N-myc is an oncogene that resides on chromosome 2p, and is amplified up to 3...
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A 50-year-old drug abuser presents with fever and weight loss. Exam shows hypeension, nodular skin rash, and peripheral neuropathy. ESR is 100 mm/L, and RBC casts are seen on urinalysis. (SELECT 1 DIAGNOSIS)
Behcet syndrome is a multisystem disorder that usually presents with recurrent oral and genital ulcers. Onefouh of patients develop superficial or deep vein thrombophlebitis. Iritis, uveitis, and nondeforming ahritis may also occur. The 50-year-old drug abuser also has a multisystem disease, including systemic complain...
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Which of the following is not a complication of surgery for thoracic outlet syndrome.
Surgical treatment in thoracic outlet syndrome has been known to have devastating complications, especially brachial plexopathy (eg, injury to the long thoracic nerve with scapular winging). Conservative treatment appears to be the most universally accepted approach, with even surgeons recommending a prolonged trial be...
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Following are true about HCO3-except:
C i.e. 7.5% solution gives 2n molsConcentration of bicarbonate- Intracellular : 10 mmoVLQ- Extracellular : 27 mmol/LQIn kidney bicarbonate is produced by carbonic anhydraseQ.
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Which is TRUE regarding nerve conduction:
A i.e. All or none phenomenon All or none law: Action potential will not develop unless the stimulus searches a threshold intensity. Once a threshold in tensity is reached, a full fledged action potential is produced. Fuher increase in the intensity of stimulus produce no increment or other change in action potential a...
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Which of the following statements about Rhythm method is false?
Anencephaly is not a repoed complication of calender method. The calender method or rhythm method: By this method, couple is advised avoidance of sexual intercourse around ovulation. In a 28-day cycle, ovulation normally occurs on the 14th day of the cycle, but may occur anytime between the 12th and 16th day. Spermatoz...
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Yoke muscle pair -
Ans. is 'c' i.e., Rt LR + Lt MRo Yoke muscle refers to the pair of muscles (one from each eye) which contract simultaneously during various movements.o For example, right lateral rectus and left medial rectus act as yoke muscles for Dextroversion movement.MovementYoke MusclesDextroelevationRight superior rectusLeft inf...
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Retinitis pigmentosa is a feature of all except -
Retinitis pigmentosa has features of : 1.Refsum's syndrome. It is characterised by retinitis pigmentosa, peripheral neuropathy and cerebellar ataxia. 2.Usher's syndrome. It includes retinitis pigmentosa and labyrinthine deafness. 3.Hallgren's syndrome. It comprises retinitis pigmentosa, vestibulocerebellar ataxia, cong...
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Employee's contribution to Employee State Insurance
According to ESI Act amendment 2019
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Bohler's angle is decreased in fracture of-
*Bohler's Tuber angle and crucial angle of Gissane are measured for Intra Aicular Fractures of Calcaneum. Ref: Apley's 9th/e p.926
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Iminoquimod is used in the treatment of -
Ans. is 'a' i.e., Anogenital wart Treatment options in wartsType of wartsTreatment optionsVarruca vulgarisCryotherapyElectric cautery, RFAWart paint (non on face, anogenital region)Mechanical removalPalmoplantar wartsWart paintCryotherapyFormain soaksFiliform wartsElectric cautery, RFAPlane wartsTrichloracetic acid tou...
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Which of the following produces irreversible cell injury faster?
Ans: c (Ischaemia) Ref: Robbins, 7th ed,p. 12Both hypoxia and ischaemia produces irreversible cell injury by reducing aerobic oxidative respiration, but ischaemia not only compromises the supply of oxygen but also compromises metabolic substrates including glucose (which is normally provided by the blood). Therefore is...
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The most reliable method of identification of an individual is: NEET 14
Ans. Galton system
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Richest source of vitamin C -
Ans. is 'a' i.e., Guava o The richest source of vitamin C is Indian goosebery (Amla),o Important sources of vitamin C in decreasing order : -Amla > Guava > Cabbage > Amaranath > Lime > Cauliflower > Orange > Spinach > Tomato > Potato
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An -HIV drug known to cause myopathy resembling Mitochondrial myopathy with ragged red Fibers?
.
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The following is true about scalenus anterior muscle -
Scalenus anterior origins from anterior tubercles of the transverse process of four typical cervical vertebrae (i.e. C3-C6) and insert on scalene tubercle and adjoining ridge on inner border and upper surface of first (1st) rib between subclavian artery and subclavian vein. Thus it separates subclavian vein from subcla...
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Commonest site of extramedullary relapse of ALL
Despite success of modern treatment,20-30% of children with ALL relapse.The main cause of treatment failure in leukemia is relapse of the disease.Common sites of relapse are the bone marrow(20%),central nervous system(5%),and testis(3%).Relapse in extramedullary sites,paicularly testes,is more ourable in terms of survi...
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Coronary aery disease is associated with all except?
Alcohol in mild amounts has been shown to have a beneficial effect on thehea. Studies have shown chlamydia and poor dental hygiene as incriminating factors for atherosclerosis. Red wine contains siuin that increases levels of H.D.L and increases longevity.
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Most common psychiatric illness -
Ans. is 'a' i.e., Depressiono Depresson is the most common psychiatric disorder that affect 15% of the population at some time in their lives (Mates - 8-12%; Females -20-25%). Middle aged (25-45 years) females are most commonly affected.o Note : Among the given options, depression is most common. Overall, anxiety disor...
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Dopamine agonist used in diabetes
Bromocriptine and cabergoline are dopamine agonists but bromocriptine usage in type 2 diabetes is approved.It has an interesting mechanism of action by inhibiting the dopamine dip that causes in early morning leading to hyperglycemia. Ref: Goodman and Gillman 13th ed
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True about pheochromocytoma is
10% are bilateral 10% are malignant 10% occur in pediatric patients 10% are extra-adrenal 10% are familial
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Raised MCV in pregnancy can be due to all except
MCV > 100fl is macrocytic First sign of megaloblastic anemia in pregnancy is usually an elevated red cell MCV Causes Megaloblastic: Folate deficiency, Vitamin B 12 deficiency and Orotic aciduria Non-Megaloblastic: Liver disease, Alcoholism, Reticulocytosis, Hypothyroidism Drugs: Azathioprine, 5-Flourouracil, Zidovudine...
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About hemothorax -a) Seen in choriocarcinomab) Supine posture is better than erect posturec) Needle aspiration may be needed for diagnosisd) Thoracotomy is always done
Hemothorax: Causes trauma (most common) tumor tuberculosis Diagnosis is made by needle aspiration of pleural fluid. Harrison writes that for making a diagnosis of hemothorax, the pleural fluid hematocrit should be > 50% of the peripheral blood. Chest X rays are taken to assess the presence and extent of pleural cavity...
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All of the following occur in mitochondria except:
Ans. B. GlycogenolysisGlycogenolysis occurs in the cytoplasm.Other metabolic reactions in the cytosol - glycolysis, glycogenesis, cholesterol synthesis, HMP shunt, bile acid synthesis
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In brachial plexus nerve arising from root is
Nerve to serratus anterior or long thoracic nerve arises from the nerve root of C5-C7. Injury to this nerve causes the condition called winging of scapula due to paralysis of serratus anterior muscle. B D Chaurasia 7th edition Page no: 45
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Range of OHI is:
The Oral Hygiene Index (OHI) was developed in 1960 by John C. Greene and Jack R. Vermillion to classify and assess oral hygiene status. To calculate the OHI, the DI and CI are summed: OHI = DI + CI  The DI and CI values range from 0 to 6. OHI value ranges from 0 to 12. Essentials of preventive and community dentistry ...
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A child come with fever, cold, cough, membrane over tonsils; nasal swab is taken, culture should be done on which medium for earliest diagnosis ?
Ans. is 'a' i.e., Loffelers serum slop Diphtheria bacilli grow on Loeffler's serum slope very rapidly and colonies can be seen in 6-8 hours, long before other bacteria grow.
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Class I MHC molecules are expressed on all Except
Class I MHC molecules are expressed on all nucleated cells and plateletsReference: Robbins and Cotran Pathologic Basis of Disease; 9th edition; Volume I; Page no: 195
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The following statements are true about Peyronie's disease except -
Peyronie's disease is usually seen over 40 years of age Impoant points about Pevronie's disease It is also k/a penile fibromatosis It is due to fibrous plaques in one or both corpus cavernosum.They may later calcify or ossify. Fibrous plaques lead to pain and curvature of the penis on erection Palpable induration or ma...
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Semi-Smoke less black powder is a mixture of
Semi-smokeless powder: It consists of a mixture of 80% black and 20% smokeless type Gunpowders: Black powder: It produces flame, smoke, and heat, and consists of granular ingredients, like sulfur, charcoal, and saltpeter (potassium nitrate) Smokeless powder: It is more effective than black powder as it burns more effic...
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Leptospira icterohemorrhagica infection is transmitted by -
Ans. is 'b' i.e., Rats
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Positive Kehrs sign is -
Ans. is 'a' i.e., Haemoperitoneum
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Best test for diagnosis of Carcinoid tumor:
Ans. (a) 24 hour urinary 5H.I.A.ARef: Harrison 19th ed. 1564-65* 5-HLAA is the major urinary metabolite of serotonin, a ubiquitous bioactive amine. Serotonin, and consequently 5-HLAA, are produced in excess by most carcinoid tumors, especially those producing the carcinoid syndrome of flushing, hepatomegaly, diarrhea, ...
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Name the procedure shown here in ureter:
Ans. (b) Dormia BasketThe use of wire baskets under image intensifier control has been replaced by ureteroscopic techniques but they may be useful when the instruments and expertise are not available
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Case of 30 year chronic smoker male, visited your clinic with this condition. Diagnosis:
Ans. (b) Buerger's disease.Buerger's disease is also known as thromboangiitis obliterans. An inflammatory and obliterative disease of blood vessels of the extremities, mainly lower extremities. Occurring chiefly in smoker young men and leading to ischemia of the tissues and gangrene. Involvement of artery vein and nerv...
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A second choice of tooth isolation is by:
Partial  isolation  with  cotton  rolls,  absorbent  wafers  and saliva  ejector  provides  rapid  and  effective  control  of  the operative field for some limited procedures in  which absolute dryness  is not required.
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Which of the following local anaesthetic has the potential to cause methamoglobinemia ?
Prilocaine is a local anaesthetic similar to lignocaine. A metabolite of prilocaine has the potential to cause methaemoglobinemia. Prilocaine is used mainly for infiltration, nerve block and for providing intravenous regional anaesthesia.
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HIV C subtype is seen in -
<p> HIV-C is most common in India. Reference:HIV/AIDS care and counselling by ACV Dyk,4th edition,page no.21.
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A 27-year-old woman occasionally uses calcium carbonate (Turns) for "heartburn" symptoms after a large meal.For the above patient with an acid-peptic disorder, select the mechanism of action of the prescribed medication.
Although doctors seldom prescribe antacids because of the availability of superior medications, patients still use them extensively. As well as neutralizing acid, calcium carbonate enhances secretion in the stomach. The release of CO2 from bicarbonate can result in belching, nausea, and abdominal distension. Belching c...
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Granulomatous inflammatory reaction is caused by all, except-
It is a distinctive pattern of chronic inflammation characterised by aggregates of Macrophages with scattered lymphocytes. Seen in all of above except mycoplasma infection. Mycoplasma species have been isolated from women with bacterial vaginosis. M. genitalium is found in women with pelvic inflammatory disease. In add...
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Antimicrobial resistance in frequent lens user is due to-
(Refer: AK Khurana Comprehensive Ophthalmology, 6th edition, pg no. 50) The contaminated contact lens provides Psuedomonas aeruginosa an idea site for attachment and biofilm production Continuous contact of the eye to the biofilm-infested lens can lead to serious ocular diseases, such as keratitis (corneal ulcers) The...
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What is your diagnosis:
Ans. D. CranioschisisCranioschisis (Greek: "kranion - kranion" skull, and "schisis -skhi/sis;" - split), or dysraphism, is a developmental birth defect involving the skull. In this disease, the cranium fails to close completely (especially at the occipital region). Thus, the brain is exposed to the amnios, and eventual...
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Subconjunctival hemorrhages are evident in the following cases except ?
Ans. is 'd' i.e., Pellagra Subconjunctival haemorrhage Occurs due to the rupture of small vessels. The condition, though unsightly, is tril. This can occur spontaneously in elderly people with fragile vessels or those with systolic hypeension or after local ocular trauma or eye surgery. Very minute ecchymoses, or possi...
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Flushing is common in patient taking which of the follwing oral hypoglycemic drug with alcohol:
Chlorpropamide is a first generation sulphonylurea. It causes cholestatic jaundice, intolerance to alcohol in predisposed subjects(flushing and a disulfiram like reaction). Disulfiram like reaction seen with: chlorpropomide, tolbutamide, metronidazole, gresiofulvin, cefoperazone, cefomandole etc (REF.Essential of medic...
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Primary cause of hyaline membrane disease is
Ans. d (Surfactant deficiency). (Ref. Nelson, Textbook of Paediatrics, 18th/731)HYALINE MEMBRANE DISEASE# Common in premature, IDM and infants delivered by caesarean section.# Clinically manifests shortly after birth (dyspnoea and cyanotic attacks).# X-ray chest shows "ground glass" mottling.# As HMD progresses, influx...
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Meckel's derived from;
Ans. (a) Proximal part of VIDRef: Sabiston 20th edition, Page 1284* Meckel's diverticulum results from incomplete closure of proximal VID* Raspberry tumor (Umbilical adenoma) is persistence of distal VID
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Effo during normal respiration is done due to ?
A i.e. Lung elasticity
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The Most common fungus to cause meningitis is
(C) Cryptococcus neoformans
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Condition which does not cause metabolic acidosis
Pyloric stenosis causes Metabolic alkalosis. Rest all causes metabolic acidosis.
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Classical cesarean section in indicated in a patient with :
Carcinoma cervix
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Hyperbilirubinemia in a child can be due to –a) Breast milk jaundiceb) Cystic fibrosisc) Fanconi's syndromed) α–1 antitrypsin deficiency
al-antitrypsin deficiency can cause cholestatic Jaundice.
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An obsessive compulsive neurosis patient is likely to develop:
Most of the patients with OCD, develop secondary depression. It is the M/C Comorbidity associated with OCD. The lifetime prevalence for major depressive disorder in persons with OCD is 67%.
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Patient with genotype X0 will have following phenotype, except: PGI 09; WB 09; MAHE 12
Ans. Tall stature
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Cell-matrix adhesions are mediated by
.
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Which type of chocking in SHOT gun produce maximum dispersion of pellets?
Firearm are of 2 types - rifled and shotgun weapons. The rifled weapon contains grooves called riffling. In shotgun no grooves are present so it is also known as smooth bore gun in which small lead shots or pellets are used which spreads to other distances when the lead pellets come out. This is called dispersion. To a...
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True statement about Antistreptolysin &;O&; titre is
In Rheumatic fever and glomerulonephritis, a retrospective diagnosis of streptococcal infection may be established by demonstrating high levels of antibody to streptococcal toxins. The standard test in antistreptolysin O titration. High levels are usually found in acute rheumatic fever but in glomerulonephritis, titers...
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Toxic epidermal necrolysis {TEN} involves body surface area
Based on body surface area ( BSA) of skin involved, epidermal necrolysis is classified into SJS: less than 10% BSASJS_TEN overlap: 10-30% BSA TEN : more than 30% BSA. From illustrated synopsis of dermatology and sexually transmitted diseases neena khanna 5th edition page no 92
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Incidence of suicide is-
C i.e. 8-10 / 1 lac population
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All are indications for surgery in bronchiectasis except:
Ans: C (Bilateral disease) Ref: Schwartz s Principles of Surgery: 9th EditionExplanation:"Patients with diffuse bilateral disease, of which cystic fibrosis is the best example, rarely benefit from resection and should be considered for lung transplantation as they approach end-stage disease. " (Ref: Schwartz)Treatment ...
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Most common type of psoriasis –
Plaque psoriasis, also known as psoriasis vulgaris is the most common type and usual form of psoriasis.
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Which of the following is not an indication of radiotherapy in Pleomorphic adenoma of parotid?
Ans. is none or (b) is the best option The above mentioned books mention the following indications of postop radiotherapy in Pleomorphic adenoma of parotid. Indications for postop radiotherapy in Pleomorphic adenoma Involvement of the deep lobe of the parotid Recurrent lesions Large (> 5 cm) lesions, which may not allo...
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The dietary fats are transmitted from GIT to adipocytes in the form of
TG derived from intestinal absorption of fats are transpoed in the blood as a lipoprotein complex called chylomicrons. Chylomicrons are small microscopic paicles of fats, about 1m in diameter and are responsible for transpo of exogenous (TG) in the blood. * Similarly, TG that are synthesised in Liver cells is conveed t...
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Splicing activity is a function of
A small nuclear RNA (snRNA) is one of many small RNA species confined to the nucleus; several of the snRNAs are involved in splicing or other RNA processing reactions.Small cytoplasmic RNAs (scRNA) are present in the cytoplasm and (sometimes are also found in the nucleus).snRNPs (snurp) are small nuclear ribonucleoprot...
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Patient presenting with cutaneous vasculitis, glomerulonephritis, peripheral neuropathy, which of the following will help in diagnosis?
Ref. API Textbook of Medicine. Pg. 1313   Cutaneous vasculitis features – Diagnosis Anti-neutrophil cytoplasmic antibodies (ANCAs): Group of autoantibodies IgG type mainly, Produced against antigens in cytoplasm of neutrophil granulocytes & monocytes. Particularly associated with systemic vasculitis, so called “ANCA-a...
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Meningococci differ from gonococci as they:
Characteristics Neisseria gonorrhoeae Neisseria meningitidis 1 Referred Gonococcus Meningococcus. 2 Vaccine Development No Serogroup A, B, C, Y and W-135 meningococcal infections can be prevented by vaccines. 3 Colony Morphology Smooth, round, moist, uniform grey/brown colonies with a greenish colour Smooth, round, moi...
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Enzyme used in Leukemia-
Asparaginase. Asparaginase is an enzyme that is used as a medication and in food manufacturing. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and non-Hodgkin's lymphoma. It is given by injection into a vein, muscle, or under the skin Ref Davidson 23rd...
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Tillaux's sign is seen in
Tillaux's sign: In mesenteric cyst, the swelling moves freely in a plane at right angles to the attachment of the mesenteryRef: Bailey and love 27e pg: 1063
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Oncogenic virus is:
Ans. is 'd' i.e., EBV (Ref: Ananthanarayan, 9th/e, p. 565 and 8th/e, p. 563)* EBV has been implicated in causation of Nasopharyngeal carcinoma and Burkitt's lymphoma.
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Integration of health services was first proposed by?
ANSWER: (B) Jungallwalla commiteREF: Park 20th ed p. 778See APPENDIX-45 below for "Health planning committee" APPENDIX - 45Health Planning CommitteeBHORECOMMITTEE1946Before 1st five year planIntegration of preventive and curative servicesPrimary health Centre (short term plan-1 PHC/40,000 population & long term plan ak...
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RNA polymerase has which activity -
Ans. is 'a' i.e., Primaseo DNA synthesis cannot commence with deoxyribonucleotides because DNA polymerase cannot add a mononucleotide to another mononucleotide.o Thus, DNA polymerase cannot initiate synthesis of complementary DNA synthesis strand of DNA on a totally single stranded template.o For this, they require RNA...
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Which of the following will give Medusa head colony on x-ray -
Ans is 'b' ie. Round worm infestation I have looked in Chapman, Sutton, Sabiston, and Schwaz without any success. Residents do not know about it (Only God Knows)
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Pupillary dilatation is seen in which of the following drug abuse ?
ATROPA BELLADONNA AND HYOSCYAMUS NIGER: Atropa belladonna/ deadly nightshade is a plant of Europe and Asia. All pas are toxic The active principle is - hyoscyamine. This group of compounds acts by inhibiting the muscarine effects of acetylcholine. Mydriatic Test: A drop of the solution to be tested is put into the eyes...
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