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Which of the following is not true about Annual Infection rate of tuberculosis ?
Ans. is 'a' i.e., 1% increase in AIR is equivalent to 70 new cases of TB Annual Infection Rate (also known as Tuberculin conversion index) o AIR is the % of population under study who will be newly infected by M. tuberculosis amongst the noninfected of the preceeding survey during the course of one year. o It reflects ...
148,800
medmcqa_train
The coagulation profile in a 13-year old girl with Menorrhagia having von Willebrands disease is
In Von willebrand disease there will be abnormal aPTT and normal PT. Activated Paial Thromboplastin Time (APTT) Test This test measures how long it takes for blood to clot. It measures the clotting ability of factors VIII (8), IX (9), XI (11), and XII (12). If any of these clotting factors is too low, it will take long...
148,801
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Pouch of Douglas is between:September 2006, March 2013
Rectouterine pouch (pouch of Douglas) is the most dependent pa of the entire peritoneal cavity (when the patient is in the standing position), hence it frequently becomes the site for the accumulation of blood (from a ruptured ectopic pregnancy) or pus (from a ruptured pelvic appendicitis or in gonococcal peritonitis)....
148,802
medmcqa_train
True about Octreotide are all, EXCEPT:
Octreotide is a synthetic analogue of Somatostatin which is administered sub-cutaneously, intra-muscularly or intra-venously but not available in the oral form. Ref: Basic and Clinical Pharmacology By Beram G. Katzung ,10th Edition, Pages 605, 1024; K D Tripathi Textbook of Pharmacology, 5th Edition, Pages 217, 622
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FAST USG focuses on all of the following areas except-
Ans. is 'c' i.e., Pleura FAST stands for Focused Abdominal Sonar for Traymao technique whereby USG is used to assess the presence of blood, either in the abdominal cavity or in the pericardium.o It is a non- invasive bed - side test,o It focuses only on four areas:PericardiumSpleenHepaticPelvic
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Which of the following viral infections is associated with highest risk of progression to fulminant disease and acute liver failure:
Answer is D (HDV/HBV Superinfection) HDV superinfection of chronic Hepatitis B is associated with a 20 percent risk of progression to fulminant hepatitis and Acute Hepatic Failure. Feature HAV HCV HEV HBV Fulminant Infection 0.1% 0.1% 1-2 % HBV : 1 % (Acute Liver Failure) in HEV pregnant p HBV/HDV Co-infection : 5 % Wo...
148,805
medmcqa_train
Which of the following cancers tends to metastatize to the lymphnodes -
Ans. is 'b' i.e., Pappilary carcinoma Papillary Ca thyroido PTC are the most common type of thyroid carcinomao More common in females with female : male ratio of 2 : 1.o Mean age at presentation is 30 to 40 yearso Most common presentation is a painless nodule in neck or a cervical lymph node (lateral aberrant thyroid)o...
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medmcqa_train
Impoant intermediate product of biosynthesis of fatty acid is
Carboxylation of Acetyl CoA The first step in the fatty acid synthesis is the carboxylation of acetyl CoA to form malonyl CoA. The acetyl CoA carboxylase is not a pa of the multienzyme complex. But it is the rate-limiting enzyme. Biotin, a member of B complex vitamins, is necessary for this reaction. The enzyme is allo...
148,807
medmcqa_train
A 6-year-old boy presented to ENT OPD with recurrent UI, mouth breathing and impaired hearing. The boy was diagnosed as having adenoid hyperophy for which adenoidectomy was done and grommet inseed; 1 week after surgery the boy was again brought to the OPD with toicollis. Which of the following are true
ADENOIDECTOMY COMPLICATIONS:- Grisel syndrome:- Patient complains of neck pain and develops toicollis. Mostly it is due to spasm of paraspinal muscles, but can be due to atlantoaxial dislocation requiring cervical collar and even traction. Ref:- Dhingra; pg num:- 432
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Which of the following drug is contraindicated in G-6PD deficiency
(Primaquine): (878-79- Harrison 18th edition; 1025-Davidson 21st)Drugs That Carry Risk of Clinical Hemolysis in Persons With G6PD Deficiency Definite RiskPossible RiskDoubtful RiskAntimalarialPrimaquineDapsone/chlorproguanilChloroquineQuinineSulphonamides / sulphonesSulfamethoxazoleOthersDapsoneSulfasalazineSulfisoxazo...
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medmcqa_train
Following statements are true about Mifepristone except:
Mifepristone: Progesterone antagonist with paial agonist activity. Administration of this drug to females early in pregnancy usually results in aboion of the fetus due to interference with the progesterone needed to maintain pregnancy. Mifepristone is often combined with the prostaglandin analog misoprostol (administer...
148,810
medmcqa_train
A 30 year old manic patient was prescribed haloperidol one week back. For last two days he has become restless and kept pacing in the room for a day. One examination he was found to have tremors of hand. he is most likely suffering from-
Ans. is 'd' i.e., Akathisia Akathisia o Restlessness, feeling of discomfo, agitation (complete desire to move about), but without anxiety. o Between 1-8 weeks of therapy. o Treatment --> Propranolol is DOC (central anticholinergic is alternative).
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The femoral ring is bounded by the following structures except
FEMORAL CANAL:- Medial compament of the femoral sheath.Conical shape, wide above and narrow below.Contents:1. Lymph node of cloquet / Rosenmuller. The lymph node drains glans penis in males and clitoris in females.2. Lymphatics 3. Areolar tissue.The base or upper end of femoral canal is called femoral ring.FEMORAL RING...
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AFP is increased in all conditions except?
Ans. is 'b' i.e., Seminoma o Repeat from previous sessions.
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True statement about transgenic mice -
Transgenic mice are generated by pronuclear injection of foreign DNA into fertilized mouse oocytes and subsequent transfer into the oviduct of pseudopregnant foster mothers. This process of generating transgenic animal would alter germ cell lines and be passed on to offsprings. So, the transgenic animals have the same ...
148,814
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The neurotransmitter secreted by postganglionic sympathetic fibers innervating sweat glands is: (Repeat)
Ans: C (Acetylcholine) Ref: Katznng, l0th edExplanation:* NE is the neurotransmilter of all postganglionic sympathetic fibers except the ones innervating the sweat glands, where acetylcholine is the neurotransmitter.Fig: Schematic diagram comparing some anatomic and neurotransmitter features of autonomic and somatic mo...
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HIV - positive patient with a viral load of 750.000 copies of HIV RNA/ml and a total CD4 count of 50 is at an increased risk for a number of infectious diseases. For which of the following diseases the paitent has no added risk than an immune complete host?
A low CD4 count does not predict progression to AIDS but does indicate increased chance of oppounistic infection such as those listed. Kaposi's sarcoma, which has been linked to herpesvirus typ 8, pneumocystis, and mycobacterial disease are three of the most prevalent oppounistic infections. While HIV- positive patient...
148,816
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Angle of tracheal bifurcation is increased in enlargement of:
Ans. Left atrium
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The pharmacokinetic propeies of a new drug are being studied in normal volunteers during phase I clinical trials. The volume of distribution and clearance determined in the first subject are 40 L and 2.0 L/hour, respectively. The half-life of the drug in this subject is approximately?
The half-life of a drug can be determined using the following equation: t1/2 = (0.693 x Vd)/Cl =0.693 X 40/2 = 13.86 ~14. Ref: Buxton I.L., Benet L.Z. (2011). Chapter 2. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination. In L.L. Brunton, B.A. Chabner, B.C. Knollmann (Eds), Goo...
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Bacteria can transfer genetic information through all of the following methods except:
Genetic information can be transferred from one bacterium to another through three methods transformation, transduction and conjugation. Methods of transfer Mechanism Nature of DNA transferred Transformation Transfer of DNA from one bacterium to another Any gene Transduction Transfer of DNA from one bacterium to anothe...
148,819
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Feature of fungal corneal ulcer is/are all except:
C. Flat and mobile hypopyonThe hypopyon, if present, is thick and immobile, and may even have a convex upper surface- Parson 22nd/199"Common symptoms of a patient with a fungal keratitis may include pain, photophobia, conjunctival injection, tearing, discharge (usually mucopurulent) and foreign-body sensation'- www.hea...
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All the following statements are true about pertussis except:
Leucocytosis does not correlate with the severity of cough.
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What is the drug of choice for management of hypeension in Pheochromocytoma?
Preoperative patient preparation is essential for safe surgery. a- Adrenergic blockers (Phenoxybenzamine) should be initiated at relatively low doses (e.g. 5-10 mg orally three times per day) and increased as tolerated every few days. Adequate alpha blockade generally requires 7 days, with a typical final dose of 20-30...
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Maxwell - Voigt model is to determine:
The simplest model that demonstrates the viscoelastic behavior is a Maxwell-Voigt model, which consists of a spring (S1) and a dashpot (D1) in series and a second set (S2 and D2) in parallel. Reference: PHILLIPS’ SCIENCE OF DENTAL MATERIALS, 12th ed page no 163
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Werneks's encephalopathy is characterized by all except
*wernicke's encephalopathy is characterised by nystagmus ,opthalmoplegia due to 6th cranial nerve involvement,ataxia and confusion. Wernicke's encephalopathy is the presence of neurological symptoms caused by biochemical lesions of the central nervous system after exhaustion of B-vitamin reserves, in paicular thiamine ...
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An anaesthetic agent with boiling temperature more than 75 C
.
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The earliest indication of concealed acute bleeding in pregnancy is :
Tachycardia
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Salter's pelvic osteotomy is done for treatment of-
Ans. is 'c' i.e., DDHTreatment of CDH/DDHo The aim of treatment in DDH is to achieve and maintain an early concentric reduction and maintain it until the hip becomes clinically stable and a round acetabulum cover it.o Treatment plan is according to the age1-6 months of agePavilk harness and/or Von-rosen splint are used...
148,827
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Two weeks after bih, a neonate develops sepsis, skin vesicles, and conjunctivitis. Over the next several days, the baby's condition deteriorates with development of seizures, cranial nerve palsies, and lethargy. The baby dies approximately one week after onset of symptoms. Which of the following infectious agents would...
This is the history of neonatal herpes that manifests as a generalized infection in the neonate. Most common cause is HSV2. HSV2 is the most common cause of genital herpes, which manifests as painful vesicular lesions that ulcerate. The site of latent infection is sacral nerve root ganglia.
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Which of the following is LEAST likely to be accompanied by lymphocytosis in the peripheral blood? (NOT RELATED)
.
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A patient had genital ulcer, with no blisters for which ASHA had given blue kit. After that patient presented with rash and fever. Which kit has to be given by ASHA to replace blue kit?
Patient has non herpetic genital ulcer (no blisters) for which blue kit was given to cover syphilis and chancroid. Patient presented with rash and fever suggestive allergy to pencillin present in blue kit. Now it has to be replaced with white kit that contains Doxycycline instead of penicillin. Blue kit : Injection ben...
148,830
medmcqa_train
A 50 year old man known to have diabetes since many years presents with poor urinary stream, hesitancy, difficulty in micturition and failure to void completely. What is he most likely suffering from?
The above mentioned clinical features of poor urinary stream, hesitancy, difficulty in micturition and failure to void completely are consistent with both BPH and autonomic neuropathy. Since the the patient is diabetic, he would most likely be suffering from diabetic autonomic neuropathy. Ref: Harrison's Principles Of ...
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In a rural clinic, a 3-year-old girl child is brought by her mother and is emaciated. Her hemoglobin was 5 g/dL. The girl also has edema over her knees and ankles with discrete rash on her knees, ankles and elbows. The most likely worm infestation causing these manifestations is:
a. Hookworm(Ref: Nelson 20/e p 1734-1735)Hookworm infestation:Leads to intestinal blood loss - iron deficiency anemia & malnutrition - growth retardationDermatitis referred to as ground itch when they penetrate human skin, manifests as vesiculation & edemaInfection with a zoonotic hookworm, especially A. braziliense cu...
148,832
medmcqa_train
who gave the repression as a defence mechanism
CONTRIBUTIONS OF FREUD o Father of psychoanalysis He founded a type of psychotherapy called psychoanalysis. It is nothing but analyzing the psych(MIND) o Interpretation of dreams According to Freud dreams are royal road to unconscious In dreams several conflicts that are present in the unconscious comes to the consciou...
148,833
medmcqa_train
Which of the following organisms causes fastest food poisoning:
Ans. (a) Staph. AureusRef.: Harriosti 18th ed. / 128y Microbiology by Ananthanarayan and Paniker 8th ed. /198Bacterial Food PoisoningIncubation period, organismSymptomsCommon sources1-6 H Staphylococcus aureusNausea, vomiting, diarrheaHam, poultry, potato or egg salad, mayonnaise, cream pastriesBacillus cereusNausea, v...
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A 32-year-old man comes to physician complaining of excessive sleepiness for the past several months. He repos falling asleep while dealing with customers, had an almost accident when he fell asleep while driving The patient repos that he occasionally hears voices while falling asleep and finds himself "temporarily fro...
The above history is suggestive of narcolepsy as patient complains of: -Excessive daytime sleepiness -Hypnagogic hallucinations(on falling asleep) -Sleep paralysis * Hypocretin, also known as orexin, is released from the hypothalamus and regulates wakefulness and arousal. * Hypocretin-1 deficiency, measured cerebrospin...
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YAG laser wave is: March 2004
Ans. A i.e. Colorless
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Pyrimidine metabolism end product
Unlike the low solubility products of purine catabolism, catabolism of the pyrimidines forms highly water-soluble products-- CO2, NH3, b-alanine, and b-aminoisobutyrate (Figure 33-12). Humans transaminate b-aminoisobutyrate to methylmalonate semialdehyde, which then forms succinyl-CoA (see Figure 19-2). Excretion of b-...
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Phagocytosis of TB bacilli does not occur because of -
Virulent strains of tubercle bacilli form microscopic "serpentine cord" in which acid fast bacilli are arranged in parallel chains, cord formation is correlated with virulence. A "cord factor" has been extracted from virulent bacilli with petroleum ether. It inhibits migration of leukocytes, causes chronic granulomas, ...
148,838
medmcqa_train
A young couple has been unsuccessful in conceiving a child over a 4-month period. The 28-year-old wife had been extensively investigated by a female reproductive specialist, and no abnormalities were detected. The husband, who initially refused to undergo semen analysis now agreed to this investigation, which revealed ...
In congenital absence of the vas deferens, mutation of the cystic fibrosis transmembrane receptor gene (CFTg) occurs. The epididymis vas deferens, seminal vesicle, membranous urethra, part of the trigone of the bladder, and ureter arise from the mesonephric duct. In the presence of a normal FSH level, testicular biopsy...
148,839
medmcqa_train
Zero orded kinetics in following drug with high dose
Zero order kinetics is seen in alcohol and theoplylline Ref-KDT 7/e p31
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A newborn has fused eyes and single nasal chamber & undeveloped callosum. What is the most probable diagnosis?
Holoprosencephaly: brain doesn't properly divide into right and left hemispheres. Associated with trisomy 13 (MC), trisomy 18, CHARGE syndrome Schizencephaly- characterized by abnormal slits or clefts in the cerebral hemispheres of the brain. Plagiocephaly- characterized by an asymmetrical distoion (flattening of one s...
148,841
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Class II elastics are used by stretching an elastic between which of the two following points?
Class II elastics work in the direction that would be used to correct a Class II malocclusion, to pull the mandibular teeth forward and the maxillary teeth distally.
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A 22-year-old woman delivers an apparently healthy female infant after an uncomplicated pregnancy. By 4 years of age, the girl has progressive, severe neurologic deterioration. Physical examination shows marked hepatosplenomegaly. A bone marrow biopsy specimen shows numerous foamy vacuolated macrophages. Analysis of wh...
The clinical features of this child neurologic involvement, hepatosplenomegaly, and accumulation of foamy macrophages - suggest a lysosomal storage disorder. One such disorder, with which the clinical history is quite compatible, is Niemann-Pick disease type A. It is characterized by lysosomal accumulation of sphingomy...
148,843
medmcqa_train
Which of the following is not true regarding Vestibular neuroma
The earliest cranial nerve involved is V nerve which causes reduced corneal sensitivity and corneal reflex. Ref: Textbook of diseases of ENT, PL Dhingra, 7th edition, pg no. 125
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Gonads to testes differentiation
SRY sex determining region on the Y chromosome . Reference: OP Ghai,essential paediatrics ,8 th edition,page no 537,fig 17.20
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All of the following are true about below procedure, except
Ans. (c) Can be used in cases of hazy ocular mediaOption a - It is a hand-held instrument, used with the examiner standing or seated slightly above the patient. It can be performed in any position.Option b - It is a uniocular examination, so Stereopsis (depth perception), Grade III of Binocular Single Vision is not pos...
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Destruction of ovaries prior to 7th week following feilization results in :
Pseudohermaphroditism: May be result of abnormalities of development of the gonads sex ducts and external genitaliaUterine agenesis: Mullerian aplasiaMasculinisation: 47,XXY UsuallySHAW&;S TEXTBOOK OF GYNAECOLOGY,Pg no:94,15th edition
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Stop codons are:
A, B, C i.e. UAA, UAG, UGA
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Addition of large amounts of platinum to a casting gold alloy will:
Platinum It increases strength and corrosion resistance. It also increases melting point and has a whitening effect on the alloy. It helps to reduce the grain size. The transformation between vapor, liquid, and solid is called the change of state. A change from the solid to the liquid state will require additional ener...
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Corneal sensation is tested by which device?
ANSWER: (C) AesthesiometerREF: Khurana 4th Ed Pg 472See PLATE O -21 KEY PLATE O-21 KEYTESTING CORNEAL SENSATIONS:(B) To test the corneal sensations, patient is asked to look ahead; the examiner touches the corneal surface with a fine twisted cotton (which is brought from the side to avoid menace reflex) and observes th...
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The autonomic nervous system of the gut, Auerbach and Meissner plexus, are embryologically derived from the following structure:
Neurons in the enteric system are derived from neural crest cells originally associated with occipitocervical and sacral regions. It regulates gastrointestinal motility, secretory activity, vascular activity, and inflammation. The first group is the myenteric plexus (also called Auerbach's plexus), which is located bet...
148,851
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Anterior fontanelle closes at:
c. 12-20 months(Ref: Nelson's 20/e p 2792)Anterior fontanelle is a diamond-shaped structure at the junction of the frontal and parietal bones, that is open at birth and usually measures 22cm. The average time of closure is 18 mo, but the fontanelle can dose normally as early as 9 months.
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A 4-yr old male child presents with muscle weakness. His mother tells that her child has difficulty in climbing stairs and getting up from the floor. On muscle biopsy, small muscle fibrils and absent of dystrophin was found. what is the diagnosis out of given options?
Duchenne Muscular Dystrophy Progressive weakness Calf muscle involvement Pseudo hyperophy Difficulty in climbing stairs Gower sign present (+) Wheel chair bound Patient Death - CHF/ Pneumonia CPK MM: Increased IOC: - PCR for dystrophin gene (Dystrophin gene absent) Rx: - Chest Physiotherapy NOTE:Immunohistochemical stu...
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Alternative for SMR:
(b) Septoplasty(Ref. Cummings, 6th ed., 481)Septoplasty is more conservative procedure than SMR and is the preferred surgery for DNS.
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The following structures do NOT have lymphatics, except
Lymph capillaries - Lymph capillaries (or lymphatic capillaries) begin blindly in tissues where they form a network. The structure of lymph capillaries is basically similar to that of blood capillaries, but is adapted for much greater permeability. There is an inner lining of endothelium. The basal lamina is absent or ...
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medmcqa_train
Investigation of choice for SPINAL METASTASIS?
MRI is the Investigation Of Choice for Most spinal imaging including: Spinal metastasis Spinal tumors Potts' spine Intramedullary spinal cord metastasis
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A 2 year old female child was brough to a PHC with a history of cough and fever for 4 days with inability to dink for last 12 hours. On examination, the child was having weight of 5 kg and respiratory rate of 45/minute with fever. The child will be classified as suffering from -
As per history, the child has fever, cough and was unable to drink. The history points to very severe disease. classification of pneumonia. Fast breathing is present when the respiratory rate is : 1. 60 breaths/min or more in child < 2 months of age. 2. 50 breaths/min or more in child aged 2-12 months. 3. 40 breaths/mi...
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Imaging studies of a patient with a genetic disorder shows 'central dot sign' which is characteristic of:
Caroli disease (Todani type V choledochal cyst) is an autosomal-recessive disorder resulting cystic dilation of the intrahepatic bile ducts. Imaging methods show intrahepatic saccular or fusiform dilated cystic structures of varying sizes that communicate with the biliary tree. The presence of tiny dots with contrast e...
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A 65 year old man has stools positive for occult blood which of the following is most likely location of bowel cancer
Distal colon cancers are M/C.
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Appropriate size of oropharyngeal airways is measured from ?
Oropharyngeal airway Guedel oropharyngeal airway (used to lift the tongue above oropharynx) Take either from the midpoint of the incisor or corner of the lip to angle of the mandible Used in unconscious person; as laryngospasm can occur in conscious person by its use
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Boundaries of upper triangular space include all except -
-        Boundaries of upper triangular space    Medial- Teres minor    Lateral- Long head of triceps    Inferior- Teres major    Content- circumflex scapular artery
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Quetlet index, used to assess obesity, is represented as ?
Ans. is 'c' i.e., Weight divided by square of Height
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What is the emergent management of tension pneumothorax?
Tension pneumothorax is a medical emergency.In case of tension pneumothorax,immediate release of the positive pressure by inseion of a large-bore needle into the pleural space through the second anterior intercostal space is beneficial.If the tension is not relieved,the patient is likely to die from inadequate cardiac ...
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Oxygen dissociation cure is shifted to left by all except -
Ans. is 'd' i.e., Decreased pH
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Treatment for 32 years old multipara with dysfunctional uterine bleeding (DUB) is :
Ans. is a i.e. Progesterones Guys, It is very impoant to clear your facts on Management of DUB and Polymenorrhea in different age groups. You must read the question very carefully as management of Polymenorrhea and DUB is different. First lets understand the basics regarding Polymenorrhea and DUB. Polymenorrhea : It is...
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The crude death rate of a population is 8/1000. So the beds for this population must be-
.
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A 39-year-old woman claims that she injured her hand at work. She asses that the pain caused by her injury prevents her from working. She has no fuher hand problems after she receives a Rs1 Lakh workers' compensation settlement. This clinical presentation is an example of
This presentation is an example of malingering, feigning illness for obvious gain (the Rs 1 lakh workers' compensation settlement). Evidence for this is that the woman has no fuher hand problems after she receives the money. In conversion disorder, somatization disorder, factitious disorder, and factitious disorder by ...
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All of the following are signs of good attachment during breast feeding EXCEPT:
Ans. (c) Lower areola is more visible than upperRef : OP Ghai 8th ed./154* I would suggest you to cram this question as it has been repeated multiple times and I think will be eternally as its a basic skill for managing patients.Please refer to above explanation.
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Which of the following is not an adverse effect of amiodarone?
Adverse effects of Amiodarone: The Thyroid (both hypo and hypehyroidism) Periphery of Peripheral neuropathy My Myocardial depression Lung Lung fibrosis Liver and Liver Toxicity Cornea is Corneal microdeposits Photosensitive Photosensitivity
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Rotigotine is ?
Ans. is 'a' i.e., Dopamine agonist Rotigotine Rotigotine is a dopamine agonist drug and is indicated in the treatment of parkinosonism. Rotigotine is intended to be delivered through transdermal patches, so as to ensure a slow and constant dosage in a 24-hour period. Side effects are--skin reaction at the patch site, n...
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Flexion extension in neck occurs at -
Ans. is 'b' i.e., Atlanto-occipital joint o Atlantoaxial joint - Rotatory movement around vertical axis (Right to left and left to right movements).o Atlanto-occipitai joint - (i) Flexion-extension around transverse axis, (ii) Slight lateral flexion around antero-posterior axis.Also knowo Atlanto-occipital joint:- Medi...
148,871
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Among the following muscles, the one that is found in the first layer of the sole is:
Flexor digitorum brevis
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Turner's syndrome is characterized by following except:
Ans. D. Tall stature. (Ref. Harrison's 18th/pg. 3049; Chapter 349.)Turner's Syndrome (Gonadal Dxsgenesis: 45.X)# PATHOPHYSIOLOGY- Approximately one-half of individuals with Turner's syndrome have a 45,X karyotype, about 20% have 45,X/46,XX mosaicism, and the remainder have structural abnormalities of the X chromosome s...
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XDR means extensive drug resistance to
Ans. (d) All of the aboveRef.: K. Park 23rd ed. /199-200Definition of Extensive Drug Resistance* Resistance to both isoniazid (H) and rifampicin, and* Resistance to 1 fluoroquinolones and* Resistance to one 2nd line injectables out of 3 (kanamycin, amikacin, capreomycin).Older Definition of XDR* Resistance of isoniazid...
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Which of the following statements about Insulinoma is true:
Answer is A (Present in Pancreas): The most common site of Insulinomas is the Pancreas.
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Bitemporal hemianopic field defect is charactersitic of:
C i.e. Pituitary tumour
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A 62-year-old man develops scaling and non-scaling patches, and plaques over his chest and back. They are itchy, but not painful. The rest of the examination is normal, except for lymphadenopathy. Examinations of the blood film and skin biopsy histology, both, reveal unusually large monocytoid cells. Which of the follo...
These large cells are typical of Sezary syndrome, a leukemic form of cutaneus T-cell lymphoma (CTCL). This is frequently an early presentation of mycosis fungoides or CTCL. There may be a relationship to human T-cell lymphotropic virus (HTLV) I and II, but it is not universal. CTCL is a malignancy of helper T cells (CD...
148,877
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In Endometrial carcinoma, which of the following tumor suppressor gene occurs?
o PTEN is a tumor suppressor gene which is implicated in the causation of endometrial and prostate carcinoma.
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Which amino acid is regarded as collector of amino groups?
First step in catabolism of amino acids is the transfer of NH3 group from amino acid to Alpha Keto- Glutarate forming Glutamate- known as Transamination. So Glutamate is regarded as collector of amino groups. Note:-The safe non-toxic form of ammonia transpo in blood from most body tissues is Glutamine. Collector is Glu...
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Breast conservation surgery is contraindicated in-
Ans. is 'a' i.e., Pregnancy Conservative breast cancer managementAbsolute ContraindicationsPregnancy is an absolute contraindication to the use of breast irradiation. However, in many cases, it may be possible to perform breast-conserving surgery in the third trimester and treat the patient with irradiation after deliv...
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A child had pustular lesion on leg. On gram staining gram positive cocci are seen. To establish the diagnosis of Group A streptococcal erythroderma, the test used is?
Streptococcal erythroderma is caused by streptococcus pyogenes. Sensitivity to bacitracin is employed as a convenient method for differentiating str.pyogenes from other hemolytic streptococci. Pustule: A vesicle filled with leukocyte. Most common cause is virus. Most common bacterial cause is str.pyogenes. Str.pyogenes...
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The term 'recrudescence' in malaria refers to:
Ans. c. Recurrence of sexual parasitemia after completion of treatment
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A male with azoospermia. On examination size of testis normal FSH normal testosterone normal. Most probable cause is
A normal level of FSH in azoospermia suggests an obstructive lesion in the vas or epididymis. High FSH may indicate primary gonadal failure.
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Reticulocytosis is not a feature of
Ref Harrison 19 th ed pg 630 Progressive CKD is usually associated with a moderate to severe hypoproliferative anemia; the level of the anemia corre- lates with the stage of CKD. Red cells are typically normocytic and normochromic, and reticulocytes are decreased.
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Which of the following antimicrobial agents act solely on the gram positive bacterial cell wall ?
Ans. is 'd' i.e., Vancomycin o Among the given options only vancomycin acts on cell wall.
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medmcqa_train
A patient presents to the emergency department with self-harm and indicates suicidal intent. Which of the following conditions does not warrant an immediate specialist assessment -
Serious physical illness, Formal thought disorders (Schizophrenia), social isolation (depression) and acute alcohol intoxication are all established risk factors for suicidal ideation / completed suicide and should be assessed by a mental health specialist. An accurate specialist assessment cannot, however, be performe...
148,886
medmcqa_train
Erb's paralysis involves -
Ans. is 'a' i.e., C5 C6ERB'S PARALYSISo One region of upper trunk (C? CJ of the brachial plexus is called Erb 'is point where six nerv es meet.Erb's pointo Injury at this point results in Erb's paralysis.o The injury is due to undue separation of the head from the shoulder, which may be seen in : -i) Birth injuryii) Fa...
148,887
medmcqa_train
Retropharyngeal space extends from base of skull to:
Retropharyngeal space: It lies behind the pharynxbetween the buccopharyngeal fascia covering pharyngeal constrictor muscles and the pre vertebral fascia. It extendsfrom the base of skull to the bifurcation of trachea. Thespace is divided into two lateral compartments (spaces ofGillette) by a fibrous raphe. Each lateral...
148,888
medmcqa_train
Dennie Morgan folds are seen in
Ans. b (Atopic dermatitis) (Ref. H - 18th/pg. 52, 52)Half of patients with Atopic dermatitis (AD) present within the first year of life, and 80% present by 5 years of age. About 80% ultimately coexpress allergic rhinitis or asthma. The infantile pattern is characterized by weeping inflammatory patches and crusted plaqu...
148,889
medmcqa_train
The maximum ozone concentration in polluted atmosphere is dependent on the concentration and ratio of nitrogen oxides and which one of the following-
Ans. is 'c' i.e., Valate organic compounds Ground level ozone is formed from Nitrogen Oxides (NO) and valati le organic compounds (VOC), e.g., Methane
148,890
medmcqa_train
All of the following causes decrease in BP except
Vasomotor discharges affect autoregulation.With sympathetic stimulation, the constant-flow, or plateau, pa of the pressure-flow curve is extended to the rightThat is, greater increases in pressure can occurSo, inhibition of vasomotor centre decreases sympathetic drive which results in decreased blood pressure. Vagal st...
148,891
medmcqa_train
In a case of acute exacerbation of asthma, salbutamol was given and no improvement noticed, intravenous corticosteroids and aminophylline was given and condition improved. What is the mechanism of corticosteroid in acute asthma?
ANS. ACorticosteroids has a dual effect in acute asthma with an early facilitatory effect on airway beta 2 adrenoreceptor sensitivity and a later effect on airway inflammation, which further emphasizes the need for corticosteroids to be administered as early as possible during an acute asthma attack.# Newer monoclonal ...
148,892
medmcqa_train
Which of the following is a negative stain:
Ans. (a) Negrosin(Ref: Bancroft's histological techniques, 7th edition)Examples of negative stain are:*Negrosin: Stains bacteria, Cryptococcus, test for viability (sperms)*India Ink: Stains Cryptococcus
148,893
medmcqa_train
Primigravida with full term, complains of faintness on lying down and se feels well when turns to side or sitting position. This is due to:
SUPINE HYPOTENSION SYNDROME (POSTURAL HYPOTENSION): During late pregnancy, the gravid uterus produces a compression effect on the inferior vena cava when the patient is in supine position. In 90% cases this, however, results in opening up of the collateral circulation by means of paravertebral and azygos veins. In some...
148,894
medmcqa_train
Myotonic dystrophy is inherited in chromosomes -
Myotonic dystrophy is associated with a trinucleotide CTG repeat expansion on chromosome 9. This expansion affects the mRNA for the dystrophila myotonia protein kinase (DMPK). Myotonic dystrophy The characteristic feature of myotonic dystrophy is myotonia, i.e., the sustained involuntary contraction of a group of mu...
148,895
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Deficiency of hypocretin leads to
Hypocretin is a neurotransmitter that promotes wakefulness and it's deficiency leads to Narcolepsy.
148,896
medmcqa_train
Which of the element is found in the active site of glutathione peroxidase for its function?
In red blood cells, the pentose phosphate pathway is the sole source of NADPH for the reduction of oxidized glutathione catalyzed by glutathione reductase, a flavoprotein containing FAD. Reduced glutathione removes H2O2 in a reaction catalyzed by glutathione peroxidase, an enzyme that contains the selenium analog of cy...
148,897
medmcqa_train
Pulmonary vascular resistance is reduced by:
Acutely increasing pulmonary venous pressure will raise capillary pressure and result in recruitment and distension of the capillaries. The other choices are incorrect because removing one lung greatly reduces the vascular bed, 10% oxygen breathing results in hypoxic pulmonary vasoconstriction, reducing lung volume to ...
148,898
medmcqa_train
All can cause pulmonary eosinophilia except-
Trichnella does not pass through the lungs during its life cycle. The other three pass through the lungs as a pa of their life cycle. They cause Loffler's syndrome - in which eosinophils accumilate in the lungs in response to parasitic infection. Strongyloides can also cause Loffler's syndrome. Reference: Ananthanaraya...
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