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All are true about achalasia except:
Ans. (b) Body peristalsis is normalRef: Sabiston 20th Edition, Pages 1015-1018Salient Points in Achalasia:* Achalasia - Meaning failure to relax* Men = women affected equally* Dysphagia, regurgitation and weight loss are the triad of symptomsPathogenesis:* Progressive inflammation and selective loss of Inhibitory myent...
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medmcqa_train
Which of the following vaccine is routinely given in pregnancy?
Td vaccine should be given to pregnant women in the second or third trimester if they had not been vaccinated in the past 10 years. If a pregnant women received Td in the past 10 years Tdap should be given postpaum. American College of Obstetricians and Gynecologists recommend that influenza vaccine should be given onl...
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D1C is common in which AML-
Ans. (b) Promyelocytic (M3)(Ref: Robbins 9th/pg 612; 8th/pg 622)Acute Promyelocytic Leukemic (APML, M3) cells can induce Disseminated intravascular coagulation (DIC)
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Which of the following cannot be done by a 3 year old child?
A child can draw a rectangle by the age of 4 years. All other options can be performed by a 3 year old child. Ref: O P Ghai, 7th Edition, Pages 26-29, 6th Edition, Page 44; Nelson, 18th Edition, Page 44.
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Which of the following is not a pyrogenic cytokine
Ref Harrison 18/e p 144;9/e p99 Interleukin-18 is a protein which in humans is encoded by the IL18 gene. The protein encoded by this gene is a proinflammatory cytokine. This cytokine is produced by many immune cells and can modulate both innate and adaptive immunity and dysregulation can cause autoimmune or inflammator...
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Basilar migraine differs from classic migraine in the
In both classic migraine and basilar migraine ,women are more susceptible. aura and visual disturbances are seen in both. But it is more severe in basilar migraine that it may lead to complete blindness, frank psychosis, quadriplegia and coma.
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Most common physiologic cause of hypoxemia is-
Ans- C Ventilation-perfusion inequality a. Although hypoventilation, incomplete oxygen diffusion, and pulmonary shunts all are causes of hypoxemia, the most common cause is ventilation-perfusion inequality. b. The mismatch of ventilation and blood flow occurs to some degree in the normal upright lung but may become ext...
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Which of the following is not a cause for neonatal jaundice manifesting for the first time in the second week: September 2008
Ans. A: Rhesus Incompatibility Jaundice appearing after 72 hours: Sepsis neonatorum' Neonatal hepatitis Extra hepatic biliary atresia Breast milk jaundice Metabolic disorders
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Disease rate is -
Disease rate is a measure of incidence or occurrence of disease in a population. In other words, it is synonymous for incidence rate.
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Which of the following antitubercular drug is not hepatotoxic :
Streptomycin and ethambutol are not hepatotoxic. Read carefully, option (c) is ethionamide, not ethambutol.
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Which of the following organs obtained from cadaver is not used for transplant? AI 11
Ans. Urinary bladder
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Fracture of the 5th metatarsal is called as -
Ans. is 'b' i.e., Jones fracture [Ref: Maheshwari 4th/e p. 2, 3EponymFractures of lower limbBumper fractureComminuted, depressed fracture of the lateral tibial condylePott's fractureBimalleolar ankle fractureCotton's fractureTrimalleolar ankle fracturePilon fractureComminuted intra-articular fracture of distal tibial e...
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All are true about epistaxis except:
Answer- C. Anterior nasal pack is easy to inse and less traumatic than balloon temponadeKeisselbach's plexus: This plexus is the commonest site of bleeding (90% of cases)Anterior nasal packing- Prophylactic antibodies should be used it pack is in a place for more than 24 hours.A balloon tamponade may be used as an alte...
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All are true about Rt kidney except :
C. i.e. Rt kidney is preferred over left kidney for transplantation- Left kidney is usually choosen for transplantation because it has longer renal vein which simplifies transplant operation.Q- Transplanted kidney is placed in iliac fossa, in the retroperitoneal position leaving native kidney in situ.- Renal vein is an...
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Defect in collagen formation is seen in:
A i.e. Scurvy Collagen show triple helixQ and is never present free inside the cytoplasmQ. Scurvy, osteogenesis imperfectaQ, Ehler - Danlos syndrome & Alpo syndrome occurs d/t its deficient synthesis.
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Preterm babies:
(Born before 37 weeks of gestations): Ref: (460-Park 20th)1. Preterm babies - babies bom too early before 37 weeks of gestations (259 days)2. Small for date (SFD) babies - bom at term or preterm. They weight less than the 10th percentile for the gestational age.3. Term: babies bom from 37 completed weeks to less than 4...
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42 yrs male with frequent attacks of joint pain, underwent an X-ray showing soft tissue swelling. The likely diagnosis is:
Tophi appear as characteristic punched out cysts or deep erosions with over hanging bony edges -Mael's or G' sign. GOUT:- Sometimes only feature is acute pain and tenderness. hyperuricemia is not diagnostic and is often seen in normal middle aged men. During acute attack X-rays show only soft tissue swelling. Chronic g...
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The drug of choice in Chorio ' Carcinoma is:
Methotrexate
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Antimalarial month is –
Antimalarial month is observed every year in month of June throughout the country, prior to the onset of mansoon and transmission season, to enhance the level of awareness and encourage community participation.
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In which of the following immunodeficiencies, this chest X-ray finding is usually seen?
Chest X-ray: pneumonia with multiple pneumatoceles, suggestive of Staphylococcal pneumonia. Recurrent abscesses and staphylococcal infection is a feature of Hyper IgE syndrome. Wiskott-Aldrich syndrome- eczema, thrombocytopenia, recurrent infections Di George syndrome- cardiac anomaly, abnormal face, thymic hypoplasia,...
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Special visceral efferent DOES NOT involve
(D) Dorsal nucleus of X cranial nerveNUCLEI BELONGING TO COLUMNSGSEOculomotor, Trochlear, Abducent, Hypoglossal nucleiSVEMotor nucleus of V nerve Motor nucleus of VII nerve Nucleus AmbiguusGVEEW nucleus, Lacrimatory nucleus, Superior & Inferior salivatory nuclei, Dorsal vagal nucleusGVA/SVANucleus of Tractus solitarius...
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A 65 year old man was seen as an outpatient complaining of central chest pain on exeion. His son tells you that 5 years ago he had been admitted for MI in the CCU of the same hospital. His vitals are stable and chest is clear. No added hea sounds are heard. What is the next best step?
The ECG shows a hea of 60/min with normal sinus rhythm. Prominent Q waves are noted in lead III, AVF indicating a previous inferior wall MI. Markedly Peaked T waves are noted in V2 and V3. Known case of ASCVD and currently is having chronic stable angina. He needs stress tests to decide the need for revascularization p...
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Swine flu is caused most commonly by -
<p> SWINE FLU:- Pandemic influenza A (H1N1). This differs from seasonal influenza in two ways. 1. Majority of population has little/no pre existing immunity to virus,the impact of the infection thus leading to wider range. 2. The virus infect the lower respiratory tract and can cause progressive pneumonia. Incubation p...
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Uterine blood flow at term is?
The massively increased uterine blood flow necessary to maintain pregnancy is made possible by significant hyperophy and remodeling of all pelvic vessels. After delivery, their caliber diminishes to approximately the size of the pre pregnant state. Uterine blood flow is increased from 50 ml/min in non pregnant states t...
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Area of brain involved in OCD: March 2004
Ans. A i.e. Basal ganglia
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All are true about congenital lymphedema except?
Ans. is 'None' Primary lymphedema has been classified on the basis of the age at onset and presence of familial clustering. a) Congenital lymphedema - has onset before the 1st year of life (according to Schwaz and Bailey onset is - congenital lymphedema can involve a single lower extremity, multiple limbs, the genitali...
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Type of collagen in brain
Type XXV is present in the brain Reference: Harper; 30th edition; Page no: 628 Table no: 50-1
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Which Congenital malformation of the fetus can be diagnosed in first trimester by ultrasound?
Ans. A. AnencephalyUltrasound can be used to detect anencephaly as early as 10 weeks' gestation. With an abnormal head/trunk ratio and abnormally large orbits, the absence of the superior vault is associated.The length of crown-rump is normal in most anencephalic fetuses.
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A 44-year-old woman comes to her physician and complains of headache and backache. On examination, she is found to have fluid accumulated in the spinal epidural space because of damage to blood vessels or meninges. Which of the following structures is most likely ruptured?
The Internal Veebral Venous Plexus is located in the spinal epidural space. The veebral aery and vein occupy the transverse foramina of the upper six cervical veebrae. The external veebral venous plexus consists of the anterior pa, which lies in front of the veebral column, and the posterior pa, which lies on the veebr...
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The resting membrane potential depends mainly on gradient of
Ans. b (Potassium). (Ref. Ganong Physiology, 21st ed., 55, 56)Myocardial action potentialPhase 0Rapid upstrokeVoltage-gated Na-channels open.Phase 1Initial repolarizationInactivation of voltage-gated Na+ balances K+ effiux.Phase 2PlateauCa2+ influx through voltage-gated Ca2+ channels balances K+ efflux.Ca2+ influx trig...
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Which hypolipidemic drug acts primarily by decreasing VLDL -
Ans. is'a'i.e., FibratesRef: KDT 6h/e p. 614; Harrison 18th/e ch. 356Fibrates (e.g. clofibrate) activate lipoprotein lipase, therefore, enhance lipolysis of triglycerides in VLDL.Statins and nicotinic acid also decrease VLDL but it is not their main mechanism of action.
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Chromic catgut suture has added advantage that is:
The chromic catgut contains the chromic salt solution to delay absorption.
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A homosexual person feels that "he is a woman trapped in a man's body" and has persistent discomfo with his sex. Most likely diagnosis is:
As mentioned in the question, the person is uncomfoable with his sex and feels that he is imposed by a female body (i.e., he is of another sex). Both are characteristics of gender identity disorder. TRANSEXUALISM: It is the severest form of gender identity disorders There is a sense of discomfo with anatomical sex orga...
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Targeted intervention programmes for HIV are done among the following group of people, EXCEPT:
The basic purpose of the targeted interventions for HIV is to reduce the rate of transmission of HIV among the most vulnerable population such as, Sex workers Intravenous drug users Homosexual men Truckers Migrant laborers Street children The main activities under these intervention projects are behaviour change, commu...
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Hypophosphatemia is seen in -
<p>Vitamin D-dependent rickets type I Rickets can be due to resistance to the action of vitamin D as well as to vitamin D deficiency. Vitamin D-dependent rickets type I, previously termed pseudovitamin D-resistant rickets , differs from true vitamin D-resistant rickets (vitamin D-dependent rickets type II, see below) i...
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X in the graph represents
Therapeutic index : LD50/ED50 Therapeutic window Range of steady-state concentrations of drug that provides therapeutic efficacy with minimal toxicity Therapeutic efficacy: Ability of a drug to activate a receptor and generate a clinical response is Therapeutic efficacy Therapeutic dose: Dose of a drug required to have...
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True about valves in portal venous system -
Although demonstrable during fetal and early neonatal period, there are no valves in a portal vein and its tributaries in the postnatal period.
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All of the following are true regarding fluid resuscitation in burn patients except:
Ans. (a) Consider intravenous resuscitation in children with burns greater than 15% TBSA* More than 10% burns in children need fluid resuscitation.
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APC gene exes its effect in combination with which of the following
Regulation of beta-catenin preventsgenes that stimulate cell division from being turned on too often and prevents cell overgrowth. The humanAPC gene is located on the long (q) arm of chromosome 5 in band q22.2 (5q22.2). The APC gene has been shown to contain an internal ribosome entry site. Refer robbins
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Case notification under international health regulations is done for which of the following: September 2009
Ans. C: Yellow fever
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Delusion of grandeur, persecution and reference is seen in: PGI 09; UP 11
Ans. Paranoid schizophrenia
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Your patient with chronic renal failure reports pruritus. Which instruction should you include in this patient’s teaching plan?
Calcium-phosphate deposits in the skin may cause pruritus. Scratching leads to excoriation and breaks in the skin that increase the patient’s risk of infection. Keeping fingernails short and clean helps reduce the risk of infection.
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During progression of normal pregnancy, S/D ratio in umblical aery ?
Ans. is 'a' i.e., DecreasesThe commonly used parameters in the umbilical aery doppler are:SD ratio: systolic velocity/diastolic velocityPulsatility index (PI) (Gosling index): (PSV - EDV)/ TAVResistive index (RI) (Pourcelot index): (PSV - EDV) / PSVNormally the parameters mentioned above should decrease progressively a...
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Most common site for carcinoma pharynx in females suffering from plummer vinson syndrome is
Ans. is 'a' i.e., Post cricoid Plummer-Vinson syndrome Plummer-Vinson syndrome, also known as Brown-Kelly-Paterson syndrome or sederopenic dysphagia, seen in middle aged edentulous women. The plummer Vinsion Paterson Brown Kelly Syndrome is characterized by : - Dysphagia Chronic iron deficiency anemia Atrophic oral muc...
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All of the following are the movements taking place during abduction of shoulder joint, EXCEPT?
Abduction of the shoulder joint is a complex movement in which the arm is carried forwards and laterally in the plane of scapula and then raised until it is directed veically above the shoulder thereby completing a movement of 180 degree. The movement involves not only the shoulder joint but requires the lateral rotati...
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A 25 year old woman complaints of bilateral hearing loss since 4 years which worsened during pregnancy. Type of tympanogram will be
answer: b) As (DHINGRA 6TH ED, P-24* Type A- normal tympanogram* Type As- (Low compliance) otosclerosis, malleus fixation* Type AD- (High compliance) ossicular discontinuity or thin and lax tympanic membrane* Type B- (No Change in compliance with pressure changes) middle ear fluid, thick tympanic membrane.* Type C- (Ma...
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Peripoal fatty infiltration of liver is seen with
MORPHOLOGIC FEATURES. The pathologic features are common to both HBV and HCV infection and include the following lesions 1.Piecemeal necrosis. Piecemeal necrosis is defined as peripoal destruction of hepatocytes at the limiting plate (piecemeal = piece by piece). Its features in chronic hepatitis are as under: i)Necros...
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Which among the following is the smallest diameter of true pelvis?
Interspinous or bispinous diameter is the distance between the tip of the two ischial spines. It measures 10.5 cm. Diagonal conjugate is the distance between the lower border of symphysis pubis to the midpoint on the sacral promontory. It measures 12 cm. True conjugate or anatomical conjugate or conjugate vera is the d...
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A 25-yr man C/O recurrent episodes of flexural eczema, contact urticaria, recurrent skin infections & severe abdominal cramps & diarrhea upon taking sea foods. He is suffering from:
Ans. B. Atopic dermatitisAtopic dermatitis is a very common, extremely itchy disorder of unknown cause which characteristically, but not always, affects the face and flexures of infants, children, adolescents and young adults. Foods, inhaled allergens, bacterial infection, reduced humidity; excessive sweating and irrit...
7,748
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The following is used for testing absorption in intestine-
Ans. is 'a' i.e.. Xylose D-xylose test : Xylose absorption test is the most commonly employed test for carbohydrateQ absorption.D - Xylose TestAim :o Assessment ofproximal small intestinal mucosal function6.Principle :o D - Xylose is a carbohydrate absorbed almost exclusively in the small intestineQ.o It does not requi...
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Arrange the following statements in order: Regarding slit skin smear steps: 1. Clean the site with methyl alcohol and pinch the skin tightly using thumb and index finger. 2. Fix the smear by moving the slide briefly over flame. 3. Make a cut on the skin fold using a scalpel and scrape out the fragments of tissue and fl...
Steps of slit skin smear: 1. Mark the slide with patient's identification number. 2. Clean the site with methyl alcohol and pinch the skin tightly using thumb and index finger. 3. Make a cut on the skin fold using a scalpel and scrape out the fragments of tissue and fluid. 4. Spread the material obtained on a clean sli...
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Which of the following is seen in APGAR score?
Ans: a (Colour) Ref: Nelson, 18th ed, p. 879; OPGhai, 6th ed, p. 144Parameters used in APGAR score* Respiratory effort* Heart rate / min* Colour of the body* Muscle tone* Reflex stimulationAPGAR score is a semi objective measure of assessing the infants respiratory, circulatory and neurological status at birthNormal ba...
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Retinal detachment occurs in which layer?
Sensory retina REP: Khurana 4th ed p. 275 "Retinal detachment is defined as separation of neurosensory retina from pigmentary retina"
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Culture media used for O157 : H7 Entero- hemorrhagic E coli -
Ans. is 'a' i.e.. Sorbitol containing agar Culture of 0157: H7 E.colio E.coli 0157:H7 is not identified on routine stool cultures.o E.coli 0157:H7 can be specifically detected by the use of modified Mac Conkey media which containssorbitol in place of lactose (SMAC).o Sorbitol Mac Conkey media is specifically useful for...
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Mechanism of action of Acyclov ir is
(D) Inhibitor of HSV polymerase # Mechanism of action:> Acyclovir differs from previous nucleoside analogues in containing only a partial nucleoside structure: the sugar ring is replaced with an open-chain structure. It is selectively converted into acyclo-guanosine monophosphate (acyclo-GMP) by viral thymidine kinase,...
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42 years old female presents diagnosed as iron deficiency anemia was staed on oral iron therapy and her Hb condition during review was 8 g%. The cause for failure of treatment is
. Poor compliance to oral iron
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Increased permeability in acute inflammation is due to all except ?
Ans. is 'c' i.e., Lytic enzymes
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Shoest incubation period is seen with
Influenza has an incubation period of 18 to 72 hours Incubation period of :- Hepatitis A : 10 to 50 days Hepatitis B : 30 to 180 days Rubella : 2 to 3 weeks Ref : Park&;s Textbook of Preventive and Social Medicine; 23rd edition
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Pulsus paradoxus is seen in-
* Pulsus paradoxus describes an exaggeration of the normal variation in systolic aerial blood pressure seen with respiration (normally falls by <10 mm on inspiration). * It is seen in the presence of- Airway obstruction. - Pericardial tamponade. - Massive pulmonary embolism. * Some conditions associated with pulsus par...
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Which of the following is not a structural gene of HIV -
tat is a nonstructural and regulatory gene of HIV REF:ANANTHANARAYANAN TEXT BOOK OF MICROBIOLOGY 9EDITION PGNO.572
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PAH is used to measure-
Ans. is 'c' i.e., Renal plasma flow * Imagine a substance that not only passes freely across the glomerular membrane but is also secreted by the tubules to such an extent that the plasma leaving the kidney does not contain that substance any more. In that case the entire plasma flowing through the kidney would be clear...
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Presence of which of the following in the urine is diagnostic of glomerular injury-
Glomerular injury is characterised by the presence of RBC casts & dysmorphic erythrocytes in urine microscopy. Ref Harrison20th edition pg 292
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Thrombocytopenia, macerated skin lesions, rash and periostitis in a new born are seen in
In Syphilis, thrombocytopenia is often associated with platelet trapping in an enlarged spleen. Characteristic osteochondritis and periostitis and a mucocutaneous rash manifesting with erythematous maculopapular or vesiculobullous lesions followed by desquamation involving hands and feet are common. Reference : Nelson ...
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In a high copper amalgam, the phase which is eliminated is:
A reaction between Cu3 Sn (ε phase) and γ2 occurs and yields Cu6Sn5  (η phase). Because of the low copper content, a majority of γ2 remains. The addition of more than 6% of copper by weight can reduce or eliminate the γ2 phase by the formation of Cu-Sn phase. Reference: PHILLIPS’ SCIENCE OF DENTAL MATERIALS, 12th ed pa...
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Analysis of visual detail occurs in which secondary visual area?
Visual information from the primary visual coex (Brodmann's area 17) is relayed to Brodmann's area 18 and then into other areas of the cerebral coex for fuher processing. Analysis of three-dimensional position, gross form, and motion of objects occurs in the posterior midtemporal area and occipitoparietal coex. Analysi...
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Dominant cell type in grey hepatization stage of community acquired pneumonia is
In the third phase grey hepatisation, no new erythrocytes are extravasating, and those already present have been lysed and degraded.  The neutrophil is the predominant cell, fibrin deposition is abundant, and bacteria have disappeared. This phase corresponds with successful containment of the infection and improvement ...
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A patient with diarrhea has a fecal smear that is negative for leukocytes. The patient&;s diarrhea is most likely caused by
The enterotoxigenic strain of Escherichia coli secretes a heat-labile toxin that stimulates adenylate cyclase, producing a cholera-like syndrome that is responsible for the majority of cases of traveler's diarrhea. Because the bowel mucosa is not invaded and there is no toxin-induced damage, the fecal smear is negative...
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Death of Poliomyelitis is due to -
Moality rate in 5-10% & is due to respiratory failure<\p> REF:MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.487
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The following condition of GB is precancerous
Porcelain gallbladder is the pattern when the gallbladder wall is calcified and cracks like an egg-shell. Porcelain gallbladdder is paicularly likely to become cancerous. Risk factors for ca gallbladder includes: 1. Gallstones 2. Genetic factors. 3.carcinogen in bile acids 4.calcificatiin of gall bladder (porcelain gal...
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A patient with acute viral hepatitis should undergo the following tests except?
For Acute Viral hepatitis patient should evaluable for Hep A Hep B Hep C IgM anti HAV lgM anti HBcAg Anti-HCV antibody *If Hep A, B, C is negative then it is Hep D Impoant Diagnostic Test in Common Liver Disease DISEASE DIAGNOSTIC TEST Hepatitis A Anti-HAV IgM Hepatitis B Acute Chronic HBsAg and anti-HBc IgM HBsAg and ...
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All symptoms are included in diagnostic criteria of major depression, except-
Ans- D
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Anti-A, anti-B, antibody appear in child -
Ans. is 'd' i.e.. After 6 months o litre of anti-A and anti-B antibodies is almost zero immedietly after birth.o Infants start producing anti-A and anti-B antibodies at age of 2-8 month when corresponding antigen is not present in cell.o Maximum titre rech at 8 to 10 years of age after that it started declinning.
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Drug of choice in Acute central anticholinergic syndrome is -
Ans. is 'b' i.e., Physostigmine Physostigmine penetrates blood-brain barrier and antagonizes both central and peripheral actions of anticholinergics in acute anticholinergic poisoning (belladonna poisoning). About other options o Neostigmine does not cross blood brain barrier. Thus it is ineffective for central anticho...
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Apparent volume of distribution of a drug exceeds total body fluid volume, if a drug is -
Ans. is 'a' i.e., Sequestrated in body tissues o Drug may have volume of distribution for in excess of total body water if it is sequestered in other tissues because most of the drug is present in tissues and plasma concentration is low.
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Abnormal a-fetoprotein is seen in
Answer is D (All of the above) All conditions mentioned in options are associated with abnormal Alpha fetoprotein levels. Open Neural tube defects and multiple gestations (twin pregnancy) are associated with elevated alpha protein levels Chromosomal trisomies (trisomy 18) show decreased alphaprotein levels.
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The true statement regarding supracondylar fracture of the humerus in children?
There are two potential problem with close reduction and cast management of fracture supracondylar humerus. The first is loss of reduction and 2nd is increased swelling and potential development of compament syndrome, secondary to immobilization with the elbow in flexion. That's why admission to hospital is essential f...
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Pelvic splanchnic nerve is formed by :
D. i.e. Ventral/ Anterior rami of Sz, S3, S4Parasympathetic supply of gastrointestinal tract from pharynx upto midgut (or proximal 2/3 transverse colon) is supplied by vagus nerve and parasympathetic supply of hindgut (i.e. distal 1/3 transverse colon onwards) is by pelvic splanchnic nerve.Vermiform appendix is derived...
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Which of the following is not used as vector in genetics?
VECTORS : The gene is trasferred to acarrier ,known as a vector.Most commonly used vectors are plasmids.Plasmids are circular double -stranded DNA molecuels seen inside bacteria. Different vector systems used for gene delivery are : Retro viruses , Adenoviruses , Adeno associated viralvectors and Herpes simplex virruse...
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Murmur increasing with valsalva maneouvre aEUR'
HOCM EFFECT OF VARIOUS INTERVENTIONS ON SYSTOLIC MURMURS
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Ring scotoma is seen in :
The hallmark symptoms of retinitis pigmentosa are night blindness (nyctalopia) and gradually progressive peripheral visual field loss as a result of increasing and coalescing ring scotomas. The most characteristic fundoscopic findings are attenuated retinal aerioles, waxy pale optic disk, mottling of the retinal pigmen...
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Flap commonly used in breast reconstruction is?
Ans. is 'b' i.e. TRAM
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In transvaginal ultrasound, earliest detection of gestation sac is by :
Ans. is d i.e. 14 days after ovulation The first definitive sonographic finding to suggest early pregnancy is visualization of the gestational sac. Using transvaginal transducers with frequency of 5 MHz, the size threshold for sac detection is 2 - 3 mm, corresponding to 4 weeks + 1 day gestational age to 4 weeks + 3 da...
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Human brain is more intelligent than monkey's brain due to:
A i.e. Larger brain The propoion of the various pas of the brain are similar in the brains of apes and human, but the human brain is largerQ, so the absolute size of the association area is greaterQ.* Brain size: Human >Chimpanzee > MonkeyQ.Weight of Human brain=1400 gm and Monkey brain = 100gmAssociation AreasAssociat...
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The Finnish type of congenital nephrotic syndrome occurs due to gene mutations the following protein:
Answer is C (Nephrin):"A mutation in the Nephrin gene causes a hereditary form of congenital Nephrotic syndrome (Finnish type) with minimal change glomerular morphology"- Nephrin is a key component of the slit diaphragmIt is a zipper like structure between podocyte foot processes that might control glomerular permeabil...
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A new born presents with deepening cyanosis at bih, with congestive hea failure and normal first hea sound. X-ray reveals cardiomegaly diagnosis is -
Ans. is 'c' i.e., Transposition of great vessels
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Distal end of humerous develops from how many centres ?
Ans. is 'd' i.e., 4Pa of humerus OssificationShaft One primary centerUpper end Three secondary centers ?One for head (appears in 1" year).One for greater tubercle (appears in 2ndeg year).One for lesser tubercle (appears in 5th year).This three centers fuses together during 6th year and finally with shaft during 20th ye...
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Transpo of neutral substances across the cell membrane occurs
D i.e. DiffusionTranspo simple passive diffusion is oured by small size, lipid solubility (hydrophobicity) absence of charge (neutrality), and absence of polarity (nonpolar nature)Q.
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Which of the following is inherited as autosomal recessive form?
Autosomal Recessive Inheritance Cystic fibrosis Phenylketonuria Tay-Sachs disease Severe combined immunodeficiency a- and b-Thalassemias Sickle cell anemia Autosomal Dominant Inheritance Familial hypercholesterolemia Marfan syndrome Ehlers-Danlos syndrome Hereditary spherocytosis Neurofibromatosis, type 1 Adult polycys...
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Most common cause of Bronchiolitis is:
a. RSV(Ref: Nelson's 20/e p 2044-2047, Ghai 8/e p 381-382Acute bronchiolitisIt is predominantly a viral disease and RSV is responsible for more than 50% of casesOther agents include parainfluenza, adenovirus, rhinovirus, Mycoplasma, human metapneumovirus and bocavirus.
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Red cell aplasia caused by:
(Chloramphenicol): Ref: 675-KDT (717-KDT 6th)* Chloramphenicol is the most important cause of aplastic anameia, agranulocytosis, thrombocytopenia or pancytopenia* PURE RED CELL APLASIA: (480-CMDT-06)Associated with -1. SLE, CLL, Lymphomas or thymoma2. Drugs - chloramphenicol, phenytoin3. Parvovirus infections* Most cas...
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Which of the following medications is contraindicated in patients with allergy to sulphonamides?
Acetazolamide, Dorzolamide and Brinzolamide are sulfonamide derivatives which act by inhibiting carbonic anhydrase (carbonic anhydrase inhibitor). Being sulphonamide derivatives they are contraindicated in patients with allergy to sulphonamides. Ref: Essentials of Pharmacology By K D Tripathi, 5th Edition, Pages 188, 5...
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Drug which produces Steven Johnson's syndrome in HIV infected individuals is:
Thiacetazone (Tzn, Amithiozone) Thiacetazone was found to be the best out of many derivatives. It was tried in the west, formd to be hepatotoxic. and discarded. In India, interest in Tzn was revived in the 1960s for oral use along with INH as a substitute for PAS. Though, its impoance has declined, it continues to be u...
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BRCA-1 gene is located at what location of the chromosome?
BRCA-1 is located at - 17q 21 BRCA-2 located at - 13q 12
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What is the age of routine screening mammography?
ANSWER: (C) 40 yearsREF: Schwartz 9th ed chapter 17, Sabiston 18th ed chapter 34, NCCN guidelines version 1.2014BREAST CANCER SCREENING NCCN GUIDELINES VERSION 1.2014Risk categoryScreening guidelinesAverage risk; age 25 to 40 yearsClinical breast examination every 1-3 yearsAverage risk; age > 40 yearsClinical breast ex...
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Broca's area is present in
Broca&;s area 44 is in the frontal lobe immediately in front of the inferior end of motor coex which is the inferior frontal gyrus. Ref: Ganong&;s review of medical physiology; 23rd edition; pg:297
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Smoking is a risk factor for all cancer except:
Smoking is not the risk factor for carcinoma gallbladder. Smoking is the risk factor for all gastrointestinal tract malignancies and hepatobiliary pancreatic tract malignancies except carcinoma gallbladder.
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Pelvic pain is mediated by
The anatomical structures that may give rise to pain in the pelvic region belong to the urinary, reproductive, and gastrointestinal systems and to their associated blood and lymphatic vessels. These structures, innervated by the somatic (T12-S5) and visceral (T10-S5) nervous system, create a complex anatomical and neur...
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Mark the wrong statement about Orbital Rhabdomyosarcoma
RHABDOMYOSARCOMA: Most Common orbital tumor in children with mean age of 5-7 years Pluripotent mesenchymal cell origin Most common site of origin: Eyelid Incidence Male > female Unilateral more common Well circumscribed homogenous tumor Superonasal quadrant is the most common location Rapidly developing proptosis is th...
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Most deaths involving placenta pre result from:
Hemorrhage
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Blue sclera is feature of -
Osteogenesis imperfecta also known as Fragilitas ossium/ Vrolick&;s disease characterised by, Fragility of bones, deafness, Blue sclera, laxity of joints and tendency to improve with age. It results from defective collagen synthesis and thus affects other collagen containing soft tissues such as the skin, sclera, teeth...
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