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At which level of heat stress index it is not possible to work comfoably causing threat to health:
HEAT STRESS INDEX(HSI): HSI% Consequence of 8 hour exposure 0 No thermal strain 10-30 Mild-Moderate heat stress, Minimal impairement in work 40-60 Severe heat stress, Threat to health if not fit 70-90 Very severe heat stress, only few can sustain it 100 Maximum heat stress, only young fit acclimatized can sustain it >1...
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Rosiglitazone mechanism of action is ?
Ans. is 'a' i.e., Acts as PPAR gamma agonist Rosiglitazone It is oral antidiabetic drug They are selective agonists for nuclear peroxisome proliferator activator receptor gamma (PPAR gamma) expressed in the fat and muscle cells. It enhances transcription of several insulin responsive genes. Reverse insulin resistance b...
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A person was brought by police from the railway platform. He is talking irrelevant. He is having dry mouth with hot skin, dilated pupils, staggering gait and slurred speech. The most probable diagnosis is:
Features of dhatura poisoning: (All Datura plants contain tropane alkaloids such as scopolamine, hyoscyamine, and atropine) Dilatation of pupils Dryness of mouth Difficulty in speech Dysphagia Dilatation of cutaneous blood vessels Dry, hot skin Drunken gait Delirium Drowsiness Reference The Synopsis of FORENSIC MEDICIN...
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Which of the following layers of epidermis is known as "prickle layer"?
Ans. B. Stratum spinosumStratum spinosum is also called as the prickle cell layer.* Stratum spinosum consists of intercellular attachments, also called desmosomes.* These desmosomes appear like spines on microscopy; hence, it is called as the prickle layer.* Their spiny (Latin, spinosum) appearance is due to the shrink...
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Energy currency of the cell is
Cellular energy can be stored in high-energy phosphate compounds, including adenosine triphosphate (ATP). This ubiquitous molecule is the energy storehouse of the body. On hydrolysis to adenosine diphosphate (ADP), it liberates energy directly to such processes as muscle contraction, active transpo, and the synthesis o...
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Commonest type of cong. cyanotic hea disease is
Most common cyanotic hea disease is tetrology of fallot encountered beyond the age of 1 yr constituting almost 75% of all blue patient. Ref : Ghai essential pediatrics,eighth edition, P.no:420
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CRF with anemia best treatment -
Ans. is 'b' i.e., Erythropoietin o Chronic kidney disease leads to normocyih normochronic anemiaThe kidney is the primary' site of erythropoietin production in the adult. Erythropoietin enhances the growth and differentiation of erythropoietin progenitors.With increasing renal dysfunction decreased level of erythropoie...
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A 32-year-old woman was admitted to the hospital with a complaint of pain over her umbilicus. Radiographic examination revealed acute appendicitis. The appendix was removed successfully in an emergency appendectomy. One week postoperatively the patient complained of paresthesia of the skin over the pubic region and the...
The ilioinguinal nerve, which arises from the L1 spinal nerve, innervates the skin on the medial aspect of the thigh, scrotum (or labia majora), and the mons pubis. It has been injured in this patient. The genitofemoral nerve splits into two branches: The genital branch supplies the scrotum (or labia majora) whereas th...
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A 70–year–old man presents with deterioration of vision 3 weeks after cataract extraction and IOL implantation. Slit lamp examination shows honeycomb maculopathy and Fluorescein angiography (FA) shows 'flower petal' hyperfluorescence. The most likely diagnosis is –
Unexpected visual loss, 3 weeks after cataract surgery with 'honey comb maculopathy' and 'flower petal' hyperfluorescence on Fluorescin Angiography is characteristic of Cystoid macular Edema.
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All of the following statements about Trientine are true, EXCEPT:
Trientine is a copper chelating agent. It is the second line of therapy in the treatment of Wilson's disease. It is less potent than penicillamine. It is used in patients intolerant to penicillamine. it can produce gastric disturbance, iron deficiency anemia due to iron chelation and sideroblastic anemia. Ref: Mitochon...
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RET gene mutation is associated with which malignancy -
Ans. is 'b' i.e., Medullary carcinoma thyroid o RET p ratoon cumene is a growth factor receptor (receptor tyrosine kinase)o The RET protein Is a receptor for the glial cell lined derived neurotrophic factor and structurally related proteins that promote cell survival during neural development.
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Most reabsorption out of
Glucose is maximumly reabsorbed in normal condition.Ref: Ganong&;s review of medical physiology; 24th edition; page no; 682
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The tumour exclusively found in parotid gland:
Wahin tumour/papillary cystadenoma lymphomatosum is viually restricted to parotid gland. Occur more commonly in male than female.
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Which of the following finding on MR imaging distinguishes vaginal atresia from mullerian agenesis
Presence of cervix distinguishes vaginal atresia from mullerian agenesis.
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Wire loop lesions are often characteristic for the following class of lupus nephritis:
Answer is C (Diffuse Proliferative Glomerutonephritis) Wire loop lesions are most charachteristic of diffuse proliferative glomerulonephritis (Class IV WHO) but may also be seen in focal proliferative glomerulonephritis (Class III WHO). Most characteristic of: Lupus Nephritis Class IV (Diffuse Lupus Nephritis) Also see...
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All are zoonotic disease EXCEPT
[Cl (Rabies) (642- Park 19th) (692-Park 20th)LISTS OF ZOONOTIC DISEASES IN MANA. Bacterial InfectionsAnthrax, Brucellosis, Ornithosis, Q-fever, Leptospirosis, Tuberculosis, PlagueB. Viral InfectionsCow pox, Monkey pox, Eastemequine encephalitis, Ross-river fever, Yellow fever, JE, Lassa fever, RabiesC. Protozoal Infect...
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Wasting of the intrinsic muscles of the hand can be expected to be due to injury which nerve ?
- Ulnar nerve innervates 15 of 20 intrinsic muscles of hand.Hence, its injury results in wasting of intrinsic muscles of hand - Musculocutaneous, radial, ulnar & median nerves are all impoant to hand function. - Musculocutaneous and radial nerves allow forearm supination; the radial nerve alone innervates the extensor ...
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Wilm's tumor is associated with all the following except :
Warn' s tamer : Wilm's tumor, also known as nephroblastoma, is the most common malignant tumor of kidney in children. Etiology. Most of the tumor are sporadic. 1- 2% may have family history. Familial predisposition to wilm's tumor is inherited in an autosornal dominant manner. Mutation of the following genes are seen ...
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Which of the following conditions is associated with maximum hearing loss?
Maximum hearing loss occur when there is ossicular interruption with intact tympanic membrane (54dB). Ossicular interruption with perforation result in 38dB hearing loss, hearing loss in ottitis media with effusion averages about 26-30 dB. Paial or complete fixation of the stapes results in conductive hearing loss that...
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Mucopolysaccharide hyaluronic acid is present in which among the following:
Hyaluronic acid is a sulphate free mucopolysaccharide. It is present in vitreous humor of the eye. It is also present in skin, synol fluid, umbilical cord, hemolytic streptococci and in rheumatic nodule. It occurs both free and salt like combination with proteins and forms ground substance of the mesenchyme, an integra...
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The development of resistance to conventional treatment has led WHO to recommned the use of combination therapies containing aemisinin derivative (aemisinin-based combination therapies also known as ACTs). All of the following combination therapies are recommended if such resistance is suspected, except -
Ans. is 'b' i.e. Aesunate plus quinine The WHO recommended ACTs (aemisinin-based combination therapies) o Aemether + lumefantrine o Aesunate + sulfadoxine-pyrimethamine o Aesunate + amodiaquine o Aesunate + mefloquine o Dihydroaemisinin + piperaquine.
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A 66-year-old man presents with a sudden onset of diabetes, anorexia, weight loss, epigastric pain with radiation to back. Next best investigation for this patient is?
Ans. B CT abdomenRef: Bailey and Love: 26th ed. page 1137* The clinical history of epigastric pain radiating to back points to pancreatic etiology. This patient may have developed pancreatic cancer. Sudden onset of diabetes in the elderly is also suggestive. The best imaging modality to image chronic pancreatitis or pa...
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Kwashiorkor is similar to marasmus in that both diseases have __________
Both marasmus and kwashiorkor are associated with anemia. Marasmus is characterized by a low calorie intake. Dietary deficiencies are compensated for by the breakdown of protein and fats. Key findings include: Growth failure, Aleness, Hunger, Monkey-like appearance , Broomstick extremities , Muscle wasting, Mild anemia...
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RD k diagnosed by:
Ans. All
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'Chancre redux' is a clinical feature of:
Chancre redux : Recurrence of the primary sore at its original site during the first two years of the disease (Relapsing stage of syphilis). Pseudochancre redux : Gummatous (teiary stage) recurrence at the site of the primary chancre.
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Gettlers test is for -
Ans. is 'd' i.e., Drowning Gettler testo Gettler test is done for drowning. It estimates chloride content of blood from both sides of heart. Normally the chloride content is equal in the right and left chambers of the heart (600 mg/100 ml). In fresh water drowning due to hemodilution the chloride content is decreased a...
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Which of the following organelles is the major site for anaerobic metabolism?
Oxidative phosphorylation occurs in the mitochondria. The TCA cycle occurs in the mitochondrial matrix. The electron transpo chain occurs on the inner mitochondrial membrane. Anaerobic metabolism occurs in the cytoplasm of most cells. The mitochondria are the site of aerobic metabolism. The Golgi apparatus is responsib...
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Mc Naughten's rule :
A i.e. Section 84
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Soft water has hardness levels of -
Level of hardness is expressed in terms of milliequivalents per litre where one milliequivalent is equal to 50mg calcium carbonate in one litre of water. The level of hardness of hard water is equal to 3-6mEq/L or 150-300 mg/L. CLASSIFICATION LEVEL OF HARDNESS (mEq./L) LEVEL OF HARDNESS (mg/L) soft water <1 <50 moderat...
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Which of the following variant of CAH presents with mineralocoicoid deficiency?
Deficiency in CAH Glucocoicoid Mineralocoicoid Androgens 21 hydroxylase Reduced Reduced Increased 3 b hydroxyl-steroide dehydrogenase Reduced Reduced Increased 11 b hydroxylase Reduced Increased Increased 17 a hydroxylase Reduced Increased Decreased P450 oxidoreductase Reduced Increased Decreased
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Indicator used in autoclave is -
Ans: b (Bacillus stearothermophilus) Ref: Ananthanarayan, 7th ed,p. 78 Autoclaving: (Moist heat) (121degC X 15 min under 15 lb/sq.inch pressure) - dressings, gloves, glass syringes, culture media, suture materials except catgut. Sterilizing control is by bacillus stearo thermophilus. Hot air oven: (Dry heat) (160degCX ...
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All of the following are done in behavior therapy to increase a behavior except:
A i.e. Punishment Punishment & frustrative-non reward lead to decrease in resultant behavior, whereas both positive & negative reinforcements increases (reinforces) the frequency of a paicular response. Operant conditioning describes how consequences of a behavior lead to an increase or decrease in that behavior. Behav...
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The cough response caused while cleaning the ear canal is mediated by stimulation of-
“Irritation of the auricular branches of the vagus in the external ear (by ear wax, syringe, etc.) may reflexly cause cough, vomiting, or even death due to sudden cardiac inhibition.” Auricular branch of the vagus nerve is also known as Arnold’s nerve or Alderman’s nerve. Also Know Similarly irritation of recurrent lar...
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O2 dissociation curve is shifted to right in all except-
Ans. is 'd' i.e., Metabolic alkalosis o Hypercapnea (raised CO2), rise in temprature and increased 2, 3 DPG cause righward shift of O2 dissociation curve,o Metabolic alkalosis causes leftward shift.o Alkalosis (increased pH), increased HbF, and hypothermia (decrease in temperature) cause a leftward shift of oxygen diss...
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True about hepatitis A viurs ?
Ans. is 'c' i.e., Common cause of hepatitis in children HAV is the most common cause of hepatitis in children. HAV does not cause chronic hepatitis or cirrhosis. HBV (no HAV) helps in HDV replication.
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The following tests may be useful in the assessment of a patient with sarcoidosis
Investigations in Sarcoidosis Lymphopenia is characteristic and liver function tests may be mildly deranged. Hypercalcaemia may be present (reflecting increased formation of calcitriol - 1,25-dihydroxyvitamin D - by alveolar macrophages), paicularly if the patient has been exposed to strong sunlight. Hypercalciuria may...
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which of the following SSRI is hea safe
SSRI * IMPOANCE Most widely prescribed antidepressant * MECHANISM Specifically acts on serotonin transpoers and increases serotonin in synapse. DRUGS FLUOXETINE FLUVOXAMINE DAPOXETINE CITALOPRAM ESCITALOPRAM ESCITALOPRAM SERALINE PAROXETINE USE FLUOXETINE=============CHILDHOOD DEPRESSION FLUVOXAMINE===========OCD DAPOX...
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Choose the appropriate lettered structure in this MRI scan showing a transaxial section through the head. Which structure may be obliterated by a pituitary tumor?
(c) The suprasellar cistern can be obliterated by a pituitary tumor.
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Pedigree Chart -
Ans. is 'c' i.e., Used to see genetic transmission Pedigreeo Provide graphic depiction of a family structure medical history'.o Person providing information is formed as pro band,o Special symbol is used for each designation,o Three generation pedigree should be made.o Closer the relationship of proband to the person, ...
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True about cornea –a) Power is 43 Db) Majority of refraction occur at air – tear interfacec) With the rule astigmatism is present because vertical meridian more steep than horizontal meridiand) Spherical structuree) Refractive index 1.334
It has already been explained in this chapter that maximum refraction occurs from the anterior surface of the cornea (at the air-tear interface) because the difference between refractive index of two medium is maximum at this site. The air has a refractive index of 1.00 and cornea has refractive index 1.376, the differ...
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Following is/ are the clinical feature/ s of lepromatous leprosy -
Ans. is 'd' i.e., All the above Important clinical features oflepromatous leprosyo Diffuse erythema, tingling, nasal stuffiness or ep is tax is are earliest manifestations.o Nodules with predeliction for external ears,o Madarosis (loss of eye lashes and eye brow s),o Saddle nose (Collapse of nasal bridge) and perforati...
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Causes of macrocephaly includes?
Causes of Megalencephaly Lysosomal storage diseases: Gangliosidosis, MPS Carbohydrate disorder: Galactosemia Aminoacidurias: Maple Syrup urine disease, Glutaric aciduria type-1 Neurogenerative diseases: Alexander disease, Canavan disease, Metachromatic leukodystrophy Neurocutaneous diseases: Neurofibromatosis, Tuberous...
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The maximum dose of isotretinoin should not exceed
Oral isotretinoin duration of treatment varies according to dose but post-therapy relapse is minimized by treatment courses that amount to the total of 120-150 mg/kg Ref Harrison 20th edition pg 1233
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Which of the following is feature of reticulocyte?
Reticulocytes are non-nucleated spherical cells bigger than normal RBCs and are polychromatic (having a blue color) d/t the presence of free ribosomes & RNA. They are identified with supravital staining. Best stain to identify them is new methylene blue.
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Nanotechnology has found tremendous application in the diagnosis of cancers because of all of following advantages, except
Ans'd. Nanocrystals exhibit a narrow difference between their excitation and emission peak spectra
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Complications of sphenoid sinus surgery are all except:
(d) Orbital emphysema(Ref. Cummings, 6th ed., 778)Orbital complications will follow maxillary, ethmoid and frontal sinus surgeries due to close proximity.
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Erosive ahritis is seen in all, except
Ref Semantischolar.org
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A 9 1/2 -year-old girl presents to your office with an approximately 1 1/4 -cm nodule in her neck, just to the left of the midline and below her cricoid cartilage. It is nontender and moves when she swallows. It has been enlarging over the last several months and was not seen by the pediatrician at her 9-year-old check...
While reactive lymphadenopathy is by far the most common cause of neck masses in children; a lymph node should not move with deglutition and is more likely to be tender. A branchial cleft syst should be more lateral and the thyroglossal duct cyst should be higher and in the midline (although they can sometimes present ...
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Site of transplantation in Islet cell transplant for Diabetes mellitus is
The islets are then purified from the dispersed tissue by density-gradient centrifugation and can be delivered into the recepient liver (the preferred site for transplantation) by injection into the poal vein Ref: Bailey and love 27th edition Pgno :1552
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A young pt presents with jaundice. Total bilirubin is 21, direct is 9.6, alkphosis 84 KA units. Diagnosis is:
Answer is D (Obstructive jaundice): Direct bilirubinemia (conjugated birirubin > 15% of total bilirubin) along with high serum alkaline phosphatase (6-7 times normal) suggests the diagnosis of obstructive jaundice. AffirghnfeAre Total bilirubin (mg/di) 0.3 to 1.0 21.0 Direct bilirubin is 45% of total bilirubin Conjugat...
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A 20 year old man presents with swelling of left lower limb and hydrocoele. All of the following may be the causative agent EXCEPT:
Ans. (d) Onchocerca volvulusRef: Diagnostic medical parasitology 3rd/275, Park 19th /221* Onchocerca volvulus results in river blindness and subcutaneous nodules.* "Lymphatic filariasis" covers infection with three closely related nematode worms - W.Bancrofti, B. Malayi and B. timoria.* All three infections are transmi...
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Very high intraocular pressure, veically oval mid-dilated pupil and shallow anterior chamber is seen in:
Ans. B: Acute primary angle closure glaucoma
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Which of the following vaccines can be used in pregnancy in normal circumstances?
Pregnancy is not a contraindication or precaution for Influenza trivalent vaccine. This vaccine is recommended for women who will be pregnant during influenza season. Influenza live attenuated vaccine is contra indicated. Must Know - Principle: Live-virus vaccines are contraindicated during pregnancy because of the pos...
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True statement about listeria:
Ans. is. 'b' i. e., Motile by peritrichous flagella
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Acute graft rejection occurs within?
Hyperacute rejection: type 2 HSR, happens over span of few minutes to hours. Eg: kidney transplant Acute rejection: Few weeks to months(< 6 months) Chronic rejection: After 6 months. Graft vs host disease (Runt Disease): Acute GVH: < 100 days Chronic GVH: > 100 days
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After an endoscopy a technician kept the instrument for sterilization. Which of the following agent is used for sterilization of fibre optic instruments?
Glutaraldehyde, which has two reactive aldehyde groups, is 10 times more effective than formaldehyde and is less toxic. It denatures proteins and nucleic acids. Both proteins and nucleic acids contain essential -NH2 and -OH groups, which are the main sites of alkylation. In hospitals, it is used to sterilize respirator...
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Cytokinee are secreted in sepsis in and systemic inflammatory response syndrome (SIRS) by:
ref Harrison 18/e p2223_2225 , Robbins 7/e p202 Cytokines are the peptide mediators or intercellular messangers which regulate immunological, inflammation,reparative host response.they are produced by widely distributed cells like macrophages ,monocytes, lymphocytes, platelets,fibroblast, endothelium,stromal cells etc....
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Necrotizing lymphadenitis is seen in:
Kikuchi Fujimoto disease Or histiocytic necrotizing lymphadenitis It is Benign and self-limited disorder in young individuals characterized by regional cervical lymphadenopathy with tenderness Accompanied with mild fever and night sweats Diagnosed on the basis of an excisional biopsy of affected lymph nodes which shows...
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Enucleation of the eyeball is contraindicated in
Endophthalmities is treated by intravitreal injection of antibiotics. If not managed and removal of eye of eye is indicated.we should go for evisceration. This is because the outer coats of the eyeball are not involved and hence we should not remove it. Also it is more convenient to put aificial eye then orbital implan...
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Colostrums has in compared to normal milk -
Colostrum contains a high concentration of proteins as compared to normal milk.REF.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE.Editon-21.Page no.-491
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The prognosis of rhabdomyosarcoma is likely to be poor if the site of the tumor is ?
Ans. is 'c' i.e. Extremity Rhabdomyosarcomas of the extremities have alveolar histology which is associated with aggressive tumor biology. Also know RMS is the most common malignant tumor of the soft tissues in infants and children. MC site is head & neck region Among head & neck, orbit is the most common site.
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Pipkin classification is used for
COMMON FRACTURES CLASSIFICATION FRACTURECLASSIFICATIONOpen fracturesGustilo & Anderson Supracondylar Humerus Galand ( based on displacement )Proximal Humerus Neer ( 4 pa fractures )Distal Radius Frykman , FermandezPelvis Young & Burgess, TileFemoral head Pipkin's classificationFemoral neck ( Pediatric )Delbet classific...
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Osteoarthritis does not affect:
Ans: d (Metacarpophalangeal joint)Ref: Maheshwari Ortho, 3rd ed, p. 252 & Harrison, 15thed, p. 1990
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Most common viral cause of acquired aqueductal stenosis is ?
Out of the given options, only mumps and toxoplasma cause aqueductal stenosis. Toxoplasma is not a virus. Hence, the answer is mumps.
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Pulsatile GnRH is used for managing:
Ans. is d, i.e. Anovulatory infertilityPulsatile GnRH is used for:* Ovulation induction (in managing anovulatory infertility)* Delayed, puberty
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The regional aerial resistance of the mesentery and kidney vessels is reduced by
In hyperdynamic sepsis, the peripheral aeriolar tone and BP are low but the cardiac output is often high; therefore the vasoconstrictor noradrenaline (norepinephrine) is appropriate to restore BP, usually at the price of some reduction in cardiac output.In most cases, a vasoconstrictor such as noradrenaline (norepineph...
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All true about pisiform, except Manipal 11
Ans. Can be seen on newborn X-ray
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Which of the following is an indication for using mifepristone?
Mifepristone, also known as RU486, is an antiprogestin that has been used for treatment of leiomyomas. Mifepristone diminishes leiomyoma volume by approximately half and it is effective in improving symptoms. Other uses of mifepristone: For termination of early pregnancy For emergency postcoital contraception Endometri...
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After passing his physical exam, a 19 year old army recruit gives urine and blood samples for fuher testing. Serum analysis yields elevated ALT, HBsAg, Anti-HBc, HBeAg, and bilirubin. All other values are normal. Which of the following is the hepatitis B status of this recruit?
The presence of elevated ALT, HBsAg, anti-HBc, HBeAg, and bilirubin all point to active hepatitis B. An asymptomatic carrier does not have elevated ALT and bilirubin. The absence of findings on physical examination rules out fulminant hepatitis B. Recovery from acute self-limited HBV is associated with the presence of ...
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Which of the following organs does not show pale infarct?
Pale infarcts are typically seen in hea, kidney and spleen. Red infarcts principally occur in organs with dual blood supply such as lungs, or in those organs with extensive collateral circulation such as brain and small intestine. In both types of infarcts, infarcted area shows coagulative necrosis, but in red infarct ...
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Mitochondrial chromosomal abnormality leads to
Ref Robbins 8/e p171;9/e p172 Example of mitochondrial inheritance is leber's hereditary optic neuropathy.leigh's disease ,MELAS - Mitochondrial encephalopathy Lactic acid Stroke like syndrome Neuropathy , ataxia, retinitis, Kearns Sayre syndromes, chronic progressive external opthalmoplegia,Pearson syndrome M
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Gestational sac is seen by TVS at-
Ans. is 'a' i.e., 5 weeks [Ref: Dutta's Obs 7th/ep. 68}TVS showso Gestational sac & yolk sac - 5th weeko Fetal pole & cardiac activity - 6th weeko Embryonic movements - 7th weeko Fetal gestational age is best determined by CRL between 7th to 12th weeks (variation +/- 5 days)o Doppler effect of ultrasound can pick up he...
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Mechanism of action of transexaminic acid is?
Ans. is 'd' i.e., Prevents fibrinolysis o Tranexamic acid binds to the lysine binding sites on plasminogen and prevents its combination with fibrin and thus prevents fibrinolysis.
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Rotator interval is between:
(c) Supraspinatus and subscapularis- Rotator interval is a triangular portion of shoulder capsule which lies between supraspinatus and subscapularis tendon and coracohumeral ligament passes through it.
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Which of the following drug is used as a Transcranial patch for Parkinson's disease
Rotigotine is a non-ergot dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS). It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours. However, it was withdrawn in 2008 because of crystal ...
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The treatment of Acute Manic Episodes is
Lithium
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Hypersensitivity vasculitis is most commonly seen in:
. Post capillary venules
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Hill Sach&;s lesion is most commonly seen in
HILL-SACH&;S lesion is most commonly seen in recurent shoulder dislocation. It is a posterolateral defect in the head of the humerus.This is produced due to the impact of posterolateral pa of the head of the humerus against the sharp anteraior margion of the glenoid rim. ref:textbook of ohopedics ,john ebnezar,4th edit...
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Natural killer cell is -
Ans. is 'c' i.e., Null cells Null cells (Large granular lymphocytes or LGLIo Null cells are called so because they lack features of surface markers of both B and T lymphocytes. The account for 5 to 10% of peripheral blood lymphocytes.o They are also called "large granular lymphocytes (LGL)"as they contain large azuroph...
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Radionucleide of choice for the assessment of renal function?
Ans: b (DTPA) Ref: Bailey, 24th ed, p. 129999Tc DTPA (diethyl triamino penta acetic acid)Useful to assess the functional status of kidney.DTPA behaves like inulin: completely filtered by the glomeruli, and not absorbed by the tubules. On using a gamma camera the dynamic action of kidney can be assessed.Other substances...
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Best drug for chemoprophylaxis in a pregnant woman who is traveling to chloroquine resistant falciparum malaria endemic zone?
Ans. A. Mefloquine. (Ref. H-17th/pg 1292; Table 203-6)Best drug for chemoprophylaxis in a pregnant woman who is traveling to chloroquine resistant falciparum malaria endemic zone is Mefloquine.Regimens for the Rx of MalariaType of Disease or RxRegimen(s)Uncomplicated Malaria Known chloroquine- sensitive strains of Plas...
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Most common nerve injured in ligation of superior thyroid aery:
The external laryngeal nerve lies in relation to superior thyroid aery. The recurrent laryngeal nerve lies close to inferior thyroid aery.
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Antiphospholipid syndrome ( APS) is associated with all of the following except:
Indications for APLA testing 3 or more consecutive first trimester losses Unexplained IUGR Early onset severe preeclampsia Unexplained thrombosis Autoimmune connective tissue diseases like SLE False positive serological test for syphilis (refer pgno:333 sheila 2nd edition)
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Duret hemorrhage seen in -
Ans. is 'a' i.e., Brain o Duret - Bernard hemorrhage can be seen with severe compression of the midbrain and other brainstem areas during transtentorial herniation.
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Which of the following is/are features of dishpan digit?
Dishpan digit Finger of the child who indulges in sucking habit. On examination, it will provide valuable information about the habits. They are: Reddened. Exceptionally clean thumb / nail / finger. Fibrous rough callus.
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Age limit for HDI?
According to previous editions of Park (21st/e) the minimum and maximum established values for life expectancy atbirth was 25 years and 85 years, respectively.   However, Now the minimum established value is 20 years and maximum value is the highest observed value during time series, i.e. the country which has the high...
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35-year-old woman presents to OPD with complains of headache after hitting her head accidentally with the wall while doing household chores . An MRI was ordered which confirmed presence of blood clot in the great cerebral vein of Galen. Obstructed vein is a direct tributary of which of the following venous structures?
Veins of the brain are direct tributaries of dural venous sinuses. Emissary veins connect dural venous sinuses with the veins of scalp; Pterygoid venous plexus communicates with cavernous sinus through an emissary vein; Diploic veins lie in channels in the diploe of skull and communicate with dural sinuses, veins of sc...
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Cystocoele is prolapse of
Cystocoele is prolapse of the anterior 2/3rd vaginal wall while prolapse of lower 1/3rd of the anterior vaginal wall is called as urethrocele. The anterior wall prolapse or cystocele is the most common form of female pelvic organ prolapse Rectocele is prolapse of lower 2/3rd of the posterior vaginal wall Enterocoele is...
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All are true about bulbar urethral rupture, except:
Ans. (b) Floating prostate on per rectal examination* Floating prostate is seen in membranous urethral injury* Perineal hematoma seen in Bulbar urethral injury.* Deep Perineal pouch hematoma is seen in Membranous urethral injury.
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Which of the following is mechanism of action of dapsone?
Dapsone is analogue of PABA Competively inhibits dihyropteroate synthase - decreases folic acid synthesis. It can cause mild hemolysis, anemia and psychosis. Uses: Leprosy Malaria Prophylaxis of pneumocystitis Dermatitis herpetiformis
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In a 4-year old boy who has history of pyogenic infections by bacteria with polysaccharide-rich capsules, which of the following investigations should he done?
Ans. d. IgA and IgG2 deficiency Recurrent episodes of pyogenic infections by capsulated organisms are most commonly observed in patients with selective IgA deficiency and decreased IgA or IgG subclass levels (especially IgG2). "Specific Antibody Deficiency (SAD) patients generally present with recurrent upper and/or lo...
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Hurthle cell tumour is:
HURTHLE CELL CARCINOMA: Hurthle cell carcinomas account for approximately 3% of all thyroid malignancies. Considered to be a subtype of follicular thyroid cancer.
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Rhinophyma is associated with-
Rhinophyma is a slow-growing benign tumor due to hypertrophy of sebaceous gland.
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Amphotericin B toxicity can be reduced by?
New amphotericin B formulations: In an attempt to improve tolerability of i.v. infusion of AMB, reduce its toxicity and achieve targeted delivery, 3 new lipid formulations of AMB have been produced. (a) Amphotericin B lipid complex (ABLC): Contains 35% AMB incorporated in ribbon like paicles of dimyristoyl phospholipid...
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Which of the following sonographic finding confirms intra uterine pregnancy
Normal gestational sac implants eccentrically in the endometrium. Anechoic center surrounded by single echogenic rim = intra-decidual sign. Two concentric rings echogenic surrounding sac = Double decidual sign.
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Founder members of vision 2020 are A/E
B i.e. UNICEF
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Which of the following is the auto antibody associated with Rheumatoid arthritis -
Anti CCP
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In preterm labour which drug has Neuro-protective role?
Ans. (a) MgSO4 Ref: Williams Obstetrics 25th Ed; Page No-730* To prevent convulsions; Administer IV MgSO4 and Continue IV MgSO4 for 24 hours after delivery.* Always avoid Nifedipine and b-blockers, because they cause severe maternal complication.Antihypertensive Drug Therapy Issues* Discontinue medications: This may be...
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Accommodation is brought about by:
Ans: d (Ciliary body contraction) Ref:Ganong, 22th ed, p. 154Accommodation is brought about by ciliary muscle contractionAccommodationThe process by which the curvature of the lens is increased is called accommodation.Mechanism: At rest the lens is under tension by lens ligaments & lens is pulled into a flattened state...
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A patient with suspected subarachnoid haemorrhage presents with blood isolated in the fouh ventricle on a CT scan. Aneurysmal rupture is likely to have resulted from
*Saccular aneurysm at size of >7mm and at top of basilar aery and at origin of posterior communicating aery are at greater risk of rupture . Ref Harrison20th edition pg 2445
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