spalde-v3-lexical stringlengths 4.95k 41.3k | _id stringlengths 4 9 | text stringlengths 174 10k | title stringlengths 2 300 |
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{"1011": 0.3910386264324188, "1052": 1.0023250579833984, "1054": 0.49864232540130615, "1996": 0.04207121208310127, "2029": 0.10291612148284912, "2079": 0.026976587250828743, "2084": 0.2478361576795578, "2087": 0.1384023278951645, "2109": 0.014542185701429844, "2179": 0.036437395960092545, "2331": 0.6022219061851501, "2... | 46617075 | Lung cancer is the leading cause of cancer related deaths accounting for more deaths than breast, colon and prostate cancers combined. The Rb-p16 regulatory pathway plays an essential role in tumor suppression in the lung epithelium. This is evidenced by the nearly universal alterations in Rb-p16 pathway components in ... | Retinoblastoma regulatory pathway in lung cancer. |
{"1016": 0.4041621685028076, "1017": 0.43434104323387146, "1018": 0.2231435477733612, "1039": 0.22704219818115234, "1044": 0.10467668622732162, "1052": 0.23633737862110138, "1058": 0.1384023278951645, "2000": 0.11951763927936554, "2001": 0.037378571927547455, "2005": 0.25239890813827515, "2007": 0.14518201351165771, "2... | 46695481 | BACKGROUND Screening for cervical cancer based on testing for human papillomavirus (HPV) increases the sensitivity of detection of high-grade (grade 2 or 3) cervical intraepithelial neoplasia, but whether this gain represents overdiagnosis or protection against future high-grade cervical epithelial neoplasia or cervica... | Human papillomavirus and Papanicolaou tests to screen for cervical cancer. |
{"1041": 0.11081436276435852, "1999": 1.0271050930023193, "2007": 0.004870930220931768, "2011": 0.27044451236724854, "2019": 0.08782484382390976, "2029": 0.21135559678077698, "2039": 0.5051454305648804, "2044": 0.4770587682723999, "2076": 0.13925230503082275, "2080": 0.8074519634246826, "2089": 0.06429435312747955, "20... | 46743299 | Chronic exercise upregulates endothelial nitric oxide synthase (eNOS) gene expression. Whether the expression of inducible nitric oxide synthase (iNOS) is affected by exercise is unknown. We therefore investigated the effects of chronic exercise on iNOS and eNOS expression in isolated rat aortic endothelial and smooth ... | Chronic Exercise Increases Both Inducible and Endothelial Nitric Oxide Synthase Gene Expression in Endothelial Cells of Rat Aorta |
{"1011": 0.08871890604496002, "1017": 0.06520967930555344, "1018": 0.07341018319129944, "1019": 0.2990913391113281, "1020": 0.12728634476661682, "1996": 0.4770587682723999, "2003": 0.07612881064414978, "2007": 0.08603433519601822, "2013": 0.036437395960092545, "2015": 0.23324857652187347, "2028": 0.055094651877880096, ... | 46764350 | The frontal lobe is the largest lobe of the brain, and it is thus commonly involved in stroke. Moreover, almost one in five strokes is limited to the prerolandic areas. This high frequency of anatomical involvement is in sharp contrast with the apparent rarity of clinical frontal dysfunction in stroke. It is remarkable... | Frontal stroke syndromes. |
{"1011": 0.6286086440086365, "1039": 0.848413348197937, "1047": 0.255429208278656, "1998": 0.14518201351165771, "2003": 0.0842406153678894, "2005": 0.5557019114494324, "2007": 0.4196864068508148, "2008": 0.05417001247406006, "2029": 0.27564704418182373, "2048": 0.18004031479358673, "2064": 0.1401015669107437, "2071": 0... | 46765242 | Cytosine arabinoside (ara-C) is widely used for the treatment of leukemias and displays significant toxicities. Lovastatin, an HMG-CoA reductase inhibitor, is extensively used to treat hypercholesterolemia. To determine whether lovastatin could augment ara-C's activity we have examined their effects in the human erythr... | Interaction of cytosine arabinoside and lovastatin in human leukemia cells. |
{"1011": 0.09850110858678818, "1015": 0.11168810725212097, "1016": 0.004870930220931768, "1052": 0.25995752215385437, "1056": 0.18978065252304077, "1060": 0.32270604372024536, "1996": 0.1485546976327896, "1997": 0.21372433006763458, "1999": 0.0038986403960734606, "2007": 0.06246116757392883, "2011": 0.35745587944984436... | 46816158 | DNA recognition by TAL effectors is mediated by tandem repeats, each 33 to 35 residues in length, that specify nucleotides via unique repeat-variable diresidues (RVDs). The crystal structure of PthXo1 bound to its DNA target was determined by high-throughput computational structure prediction and validated by heavy-ato... | The crystal structure of TAL effector PthXo1 bound to its DNA target. |
{"1039": 0.37640097737312317, "2013": 0.09050461649894714, "2051": 0.0174254160374403, "2084": 0.022212404757738113, "2090": 0.27786844968795776, "2099": 1.1450434923171997, "2116": 0.21530038118362427, "2129": 0.08603433519601822, "2146": 0.33953672647476196, "2158": 0.2990913391113281, "2168": 0.016465263441205025, "... | 46837626 | A formula has been developed to predict creatinine clearance (Ccr) from serum creatinine (Scr) in adult males: (see article)(15% less in females). Derivation included the relationship found between age and 24-hour creatinine excretion/kg in 249 patients aged 18-92. Values for Ccr were predicted by this formula and four... | Prediction of creatinine clearance from serum creatinine. |
{"1048": 0.9485763907432556, "1056": 0.8109301924705505, "1996": 0.09938567131757736, "1998": 0.12384103983640671, "2005": 0.006812678650021553, "2007": 0.10993985831737518, "2011": 0.34300774335861206, "2013": 0.1477125883102417, "2015": 0.06612417846918106, "2029": 0.03360854089260101, "2046": 0.4311734735965729, "20... | 46926352 | Immune cells continuously recirculate through lymph vessels en route from peripheral tissues to the blood. Leuyte trafficking into and within lymph vessels is mediated by an interply with lymphatic endothelial cells (LECs). However, lymphatic vessels are much more than mere conduits for fluid and immune cell transport.... | Dendritic cells, T cells and lymphatics: dialogues in migration and beyond. |
{"1011": 0.06337817758321762, "1023": 0.3084607720375061, "1052": 0.8965662121772766, "2008": 0.04674193635582924, "2011": 0.2317005842924118, "2029": 0.1905880719423294, "2064": 0.025073638185858727, "2079": 0.14939609169960022, "2099": 0.6654226183891296, "2106": 0.0009760859538801014, "2109": 0.09050461649894714, "2... | 47018050 | Here, we report that genome editing by CRISPR–Cas9 induces a p53-mediated DNA damage response and cell cycle arrest in immortalized human retinal pigment epithelial cells, leading to a selection against cells with a functional p53 pathway. Inhibition of p53 prevents the damage response and increases the rate of homolog... | CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response |
{"1015": 0.38308101892471313, "1018": 0.034552380442619324, "1020": 0.2501201331615448, "1040": 0.08603433519601822, "1043": 0.3662964701652527, "1055": 0.6674286723136902, "1998": 0.083342544734478, "2003": 0.2026219218969345, "2024": 0.2659635543823242, "2034": 0.3877306580543518, "2060": 0.06795065850019455, "2064":... | 47240151 | BACKGROUND Steroidogenic acute regulatory (StAR) protein related lipid transfer (START) domains are small globular modules that form a cavity where lipids and lipid hormones bind. These domains can transport ligands to facilitate lipid exchange between biological membranes, and they have been postulated to modulate the... | Comparative Structural Analysis of Lipid Binding START Domains |
{"1052": 0.1485546976327896, "1055": 0.7692760229110718, "1060": 0.0797421783208847, "1999": 0.0913962796330452, "2003": 0.12642613053321838, "2004": 0.4356052577495575, "2036": 0.26146242022514343, "2038": 0.02887592278420925, "2042": 0.09050461649894714, "2050": 0.3676496744155884, "2058": 0.3777405619621277, "2060":... | 49208216 | Staphylococcus aureus is a human commensal that can also cause systemic infections. This transition requires evasion of the immune response and the ability to exploit different niches within the host. However, the disease mechanisms and the dominant immune mediators against infection are poorly understood. Previously i... | Staphylococcus aureus infection dynamics |
{"1020": 0.14686977863311768, "1021": 0.052318159490823746, "1042": 0.5255602598190308, "1048": 0.7229714393615723, "2000": 0.11778303235769272, "2011": 0.2852376699447632, "2050": 0.48970574140548706, "2058": 0.0038986403960734606, "2064": 0.23402166366577148, "2065": 0.08782484382390976, "2075": 0.14518201351165771, ... | 49429882 | BACKGROUND The growing appreciation of the multi-faceted importance of optimal maternal nutrition to the health and development of the infant and young child is tempered by incompletely resolved strategies for combatting challenges. OBJECTIVE To review the importance of maternal nutrition and strategies being employed ... | Strategies for optimizing maternal nutrition to promote infant development |
{"1011": 0.07341018319129944, "1016": 0.10291612148284912, "1017": 0.27712854743003845, "1018": 0.3248254358768463, "2005": 0.11604541540145874, "2011": 0.009718249551951885, "2015": 0.319873183965683, "2024": 0.22548456490039825, "2045": 0.5209306478500366, "2048": 0.02887592278420925, "2057": 0.04767346754670143, "20... | 49432306 | The introduction of immune-checkpoint blockade in the cancer therapy led to a paradigm change of the management of late stage cancers. There are already multiple FDA approved checkpoint inhibitors and many other agents are undergoing phase 2 and early phase 3 clinical trials. The therapeutic indication of immune checkp... | Key questions about the checkpoint blockade-are microRNAs an answer? |
{"1015": 0.045809537172317505, "1018": 0.05417001247406006, "1038": 0.47827014327049255, "1042": 0.15693697333335876, "1047": 0.040196798741817474, "2003": 0.3743882179260254, "2011": 0.013579257763922215, "2026": 0.5562619566917419, "2054": 0.16524957120418549, "2073": 0.058784693479537964, "2079": 0.06429435312747955... | 49556906 | Fibrosis is a pathological result of a dysfunctional repair response to tissue injury and occurs in a number of organs, including the lungs1. Cellular metabolism regulates tissue repair and remodelling responses to injury2-4. AMPK is a critical sensor of cellular bioenergetics and controls the switch from anabolic to c... | Metformin reverses established lung fibrosis in a bleomycin model |
{"1047": 0.10555581003427505, "1998": 0.4752389192581177, "2000": 0.10026945173740387, "2005": 0.0019512200960889459, "2007": 0.09406650811433792, "2062": 0.4437839686870575, "2064": 0.24859806895256042, "2071": 0.14939609169960022, "2079": 0.21372433006763458, "2086": 0.14939609169960022, "2090": 0.25845035910606384, ... | 50670403 | SUMMARY Recent literature has demonstrated the usefulness of fitness and computer-based cognitive training as a means to enhance cognition and brain function. However, it is unclear whether the combination of fitness and cognitive training that results from years of extensive sport training also results in superior per... | Are expert athletes 'expert' in the cognitive laboratory? A meta-analytic review of cognition and sport expertise |
{"1011": 0.11430477350950241, "1014": 0.20022670924663544, "1020": 0.1946154683828354, "1041": 0.755608320236206, "1052": 0.02792670577764511, "1596": 0.6773988008499146, "2001": 0.043007105588912964, "2012": 0.20977331697940826, "2015": 0.43875885009765625, "2020": 0.12038381397724152, "2029": 0.18167030811309814, "20... | 51386222 | Objective. —To examine more closely the association between apolipoprotein E (APOE) genotype and Alzheimer disease (AD) by age and sex in populations of various ethnic and racial denominations. Data Sources. —Forty research teams contributed data onAPOEgenotype, sex, age at disease onset, and ethnic background for 5930... | Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis |
{"1038": 0.13670019805431366, "1043": 1.0492360591888428, "2003": 0.34922540187835693, "2011": 0.004870930220931768, "2013": 0.0058422754518687725, "2062": 0.04953393340110779, "2064": 0.007782140281051397, "2083": 0.6420594453811646, "2087": 0.5562619566917419, "2100": 0.11517547070980072, "2119": 0.1229778528213501, ... | 51706771 | Glioblastoma (GBM) is the most aggressive and common form of brain cancer in adults. GBM is characterized by poor survival and remarkably high tumors heterogeneity (both intertumoral and intratumoral), and lack of effective therapies. Recent high-throughput data revealed heterogeneous genetic/genomic/epigenetic feature... | Comparison of glioblastoma (GBM) molecular classification methods. |
{"1011": 0.09317722171545029, "1039": 0.020300358533859253, "1043": 0.0354953333735466, "1049": 0.0354953333735466, "2003": 0.018384648486971855, "2005": 0.12038381397724152, "2011": 0.0058422754518687725, "2022": 0.13414156436920166, "2024": 0.03925827145576477, "2033": 0.817850649356842, "2034": 0.27044451236724854, ... | 51728753 | Over the last decades, mesenchymal stromal cells (MSC) have been the focus of intense research by academia and industry due to their unique features. MSC can be easily isolated and expanded through in vitro culture by taking full advantage of their self-renewing capacity. In addition, MSC exert immunomodulatory effects... | Mesenchymal Stromal Cells: From Discovery to Manufacturing and Commercialization |
{"1011": 0.3956514894962311, "1044": 0.7528522610664368, "1055": 0.25467249751091003, "1997": 0.2247048318386078, "1998": 0.3423145115375519, "2002": 1.3346925973892212, "2003": 0.12556517124176025, "2004": 0.009718249551951885, "2008": 0.020300358533859253, "2010": 0.9658246636390686, "2014": 1.0116009712219238, "2015... | 51817902 | Hes and Hey genes are the mammalian counterparts of the Hairy and Enhancer-of-split type of genes in Drosophila and they represent the primary targets of the Delta-Notch signaling pathway. Hairy-related factors control multiple steps of embryonic development and misregulation is associated with various defects. Hes and... | Delta–Notch—and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors |
{"1011": 0.3005385100841522, "1048": 0.7592713832855225, "1052": 0.47463157773017883, "1999": 0.4158279001712799, "2004": 0.026976587250828743, "2009": 0.5092619061470032, "2011": 0.3127557039260864, "2013": 0.0009760859538801014, "2026": 0.8135309815406799, "2039": 0.12814582884311676, "2044": 0.7491656541824341, "205... | 51865482 | BACKGROUND Adult mammalian heart loses regeneration ability following ischemic injury due to the loss of cardiomyocyte mitosis. However, the molecular mechanisms underlying the post-mitotic nature of cardiomyocytes remain largely unknown. OBJECTIVES The purpose of this study was to define the essential role of long non... | The Long Noncoding RNA CAREL Controls Cardiac Regeneration. |
{"1011": 0.1485546976327896, "1015": 0.4788752794265747, "1017": 0.16110190749168396, "1038": 0.7629209756851196, "1056": 0.9363996982574463, "1998": 0.2983669638633728, "2007": 0.10906458646059036, "2008": 0.10731173306703568, "2026": 0.3526630103588104, "2028": 0.09317722171545029, "2029": 0.32270604372024536, "2033"... | 51952430 | The toll-like receptor (TLR) and interleukin (IL)-1 family of receptors share several signaling components, including the most upstream adapter, MyD88. We previously reported the discovery of B cell adapter for phosphoinositide 3-kinase (BCAP) as a novel toll-IL-1 receptor homology domain-containing adapter that regula... | BCAP links IL-1R to the PI3K–mTOR pathway and regulates pathogenic Th17 cell differentiation |
{"1021": 0.07793712615966797, "1044": 0.1477125883102417, "2000": 0.151916041970253, "2001": 0.07884006202220917, "2004": 0.018384648486971855, "2005": 0.15275461971759796, "2012": 0.7028654217720032, "2020": 0.18167030811309814, "2025": 0.053244512528181076, "2038": 0.34922540187835693, "2040": 0.9100211262702942, "20... | 51972698 | Problem Samoa has been struggling to address the burden of noncommunicable diseases at the health system, community and individual levels. Approach The World Health Organization (WHO) package of essential noncommunicable disease interventions for primary health care in low-resource settings was adopted in seven village... | Adapting the WHO package of essential noncommunicable disease interventions, Samoa |
{"1003": 0.1485546976327896, "1014": 0.12642613053321838, "1018": 0.0913962796330452, "1019": 0.010684899985790253, "1020": 0.006812678650021553, "1021": 0.1212492436170578, "1022": 0.13499516248703003, "1023": 0.08871890604496002, "1997": 0.022212404757738113, "2012": 0.47584590315818787, "2015": 0.10291612148284912, ... | 52072815 | Summary Background Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to health accounting within the Global Burden of Diseases, I... | Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 |
{"1011": 0.11256109178066254, "1018": 0.3034266233444214, "1048": 0.3170322775840759, "1049": 0.0606246218085289, "1050": 0.48430517315864563, "1055": 0.34300774335861206, "1056": 1.1406835317611694, "1164": 0.5180262327194214, "2011": 0.3034266233444214, "2029": 0.09584271162748337, "2046": 0.02412080205976963, "2063"... | 52095986 | Although the etiology of multiple sclerosis (MS) remains enigmatic, the role of T cells is unquestionably central in this pathology. Immune cells respond to pathogens and danger signals via pattern-recognition receptors (PRR). Several reports implicate Nlrp12, an intracellular PRR, in the development of a mouse MS-like... | The Dual Immunoregulatory function of Nlrp12 in T Cell-Mediated Immune Response: Lessons from Experimental Autoimmune Encephalomyelitis |
{"1003": 0.0842406153678894, "1020": 0.037378571927547455, "1041": 0.41065993905067444, "1044": 0.6358738541603088, "1045": 0.06612417846918106, "1048": 0.5618454217910767, "1050": 0.29473719000816345, "1058": 0.3897167444229126, "1606": 0.28082266449928284, "2004": 0.2160874605178833, "2007": 0.2026219218969345, "2012... | 52175065 | KEY POINTS The vascular endothelial growth factor (VEGF) responses to acute submaximal exercise and training effects in patients with heart failure with reduced ejection fraction (HFrEF) were investigated. Six patients and six healthy matched controls performed knee-extensor exercise (KE) at 50% of maximum work rate be... | Acute and chronic exercise in patients with heart failure with reduced ejection fraction: evidence of structural and functional plasticity and intact angiogenic signalling in skeletal muscle |
{"1003": 0.09850110858678818, "1009": 0.4462870955467224, "1039": 0.02316705882549286, "1040": 0.21214580535888672, "1049": 0.15693697333335876, "1055": 0.014542185701429844, "1056": 0.28082266449928284, "1081": 0.45623743534088135, "2005": 0.056018441915512085, "2007": 0.3982778787612915, "2015": 0.6921701431274414, "... | 52176296 | To investigate the impact of the 2017 revisions of McDonald criteria on the diagnosis of multiple sclerosis (MS) in a cohort of patients with clinically isolated syndrome (CIS) and dissemination in space (DIS) of demyelinating lesions. We retrospectively analyzed 137 patients with CIS + DIS from two Italian MS centers.... | 2017 revisions of McDonald criteria shorten the time to diagnosis of multiple sclerosis in clinically isolated syndromes |
{"1011": 0.45499902963638306, "1014": 0.3588210940361023, "1015": 0.8837352395057678, "1040": 0.38374659419059753, "1048": 0.7995813488960266, "1052": 0.66441810131073, "1998": 0.16442140936851501, "2005": 0.11343330889940262, "2006": 0.07431721687316895, "2007": 0.1946154683828354, "2010": 0.8780695199966431, "2011": ... | 52180874 | OBJECTIVE To evaluate the relative efficacy of programmed cell death 1 (PD-1) or programmed cell death ligand 1 (PD-L1) inhibitors versus conventional drugs in patients with cancer that were PD-L1 positive and PD-L1 negative. DESIGN Meta-analysis of randomised controlled trials. DATA SOURCES PubMed, Embase, Cochrane da... | Efficacy of PD-1 or PD-L1 inhibitors and PD-L1 expression status in cancer: meta-analysis |
{"1003": 0.22548456490039825, "1014": 0.1485546976327896, "1023": 0.15023678541183472, "1043": 0.5947071313858032, "1997": 0.36358460783958435, "2045": 0.5393219590187073, "2047": 0.5427330136299133, "2062": 0.08782484382390976, "2087": 0.603290855884552, "2088": 0.841701865196228, "2095": 0.2749055027961731, "2097": 0... | 52188256 | This article provides a status report on the global burden of cancer worldwide using the GLOBOCAN 2018 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer, with a focus on geographic variability across 20 world regions. There will be an estimated 18.1 million new canc... | Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. |
{"1016": 0.3005385100841522, "1017": 0.014542185701429844, "1056": 0.9754437208175659, "1059": 0.32270604372024536, "1999": 0.06429435312747955, "2011": 0.24631060659885406, "2015": 0.07341018319129944, "2020": 0.013579257763922215, "2038": 0.020300358533859253, "2046": 0.5579402446746826, "2052": 0.011650617234408855,... | 52805891 | Environmental factors and host genetics interact to control the gut microbiota, which may have a role in the development of obesity and insulin resistance. TLR2-deficient mice, under germ-free conditions, are protected from diet-induced insulin resistance. It is possible that the presence of gut microbiota could revers... | Gut Microbiota Is a Key Modulator of Insulin Resistance in TLR 2 Knockout Mice |
{"1011": 0.2881702482700348, "1016": 0.4974553883075714, "1048": 0.9754437208175659, "1056": 1.0001721382141113, "1156": 0.7510106563568115, "2004": 0.012615402229130268, "2011": 0.14095009863376617, "2015": 0.1221139207482338, "2029": 0.20739519596099854, "2046": 0.2689530849456787, "2048": 0.18816383183002472, "2071"... | 52824661 | Previous studies indicated that transforming growth factor (TGF)-β-mediated exosomal microRNAs (miRNAs) regulate the migration and invasion of lung cancer cells; however, whether and how TGF-β-mediated exosomal long noncoding (lnc) RNAs regulate migration and invasion of lung cancer cells remains unclear. Here, cocultu... | TGF‐β‐mediated exosomal lnc‐MMP2‐2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression |
{"1018": 0.05139094591140747, "1019": 0.0174254160374403, "1053": 0.04487626627087593, "1997": 0.5057345628738403, "1998": 0.0058422754518687725, "2000": 0.28082266449928284, "2001": 0.16276304423809052, "2004": 0.0842406153678894, "2005": 0.18978065252304077, "2007": 0.3824150264263153, "2020": 0.2145126610994339, "20... | 52827184 | Objective: To provide an update to “Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012. ” Design: A consensus committee of 55 international experts representing 25 international organizations was convened. Nominal groups were assembled at key international meetings (for those committee... | Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2016 |
{"1017": 0.006812678650021553, "1060": 0.7220231294631958, "2003": 0.020300358533859253, "2005": 0.018384648486971855, "2029": 0.05046287178993225, "2035": 0.09495500475168228, "2042": 0.08692999184131622, "2054": 0.004870930220931768, "2057": 0.009718249551951885, "2079": 0.0038986403960734606, "2090": 0.1290045678615... | 52850476 | The analysis of mitochondrial DNA (mtDNA) has been a potent tool in our understanding of human evolution, owing to characteristics such as high copy number, apparent lack of recombination, high substitution rate and maternal mode of inheritance. However, almost all studies of human evolution based on mtDNA sequencing h... | Mitochondrial genome variation and the origin of modern humans. |
{"1011": 0.5562619566917419, "1044": 0.4450363218784332, "1045": 0.06612417846918106, "1999": 0.03925827145576477, "2003": 0.21372433006763458, "2005": 0.07612881064414978, "2006": 0.055094651877880096, "2011": 0.42416930198669434, "2043": 0.030771657824516296, "2076": 0.37974658608436584, "2078": 0.04767346754670143, ... | 52865789 | OBJECTIVE IL-15 is an inflammatory cytokine secreted by many cell types. IL-15 is also produced during physical exercise by skeletal muscle and has been reported to reduce weight gain in mice. Contrarily, our findings on IL-15 knockout (KO) mice indicate that IL-15 promotes obesity. The aim of this study is to investig... | Deficiency of Interleukin-15 Confers Resistance to Obesity by Diminishing Inflammation and Enhancing the Thermogenic Function of Adipose Tissues |
{"1011": 0.07612881064414978, "1017": 0.3864043951034546, "1041": 0.33115679025650024, "1044": 0.817850649356842, "2002": 0.018384648486971855, "2003": 0.022212404757738113, "2005": 0.32199856638908386, "2011": 0.16359257698059082, "2029": 0.11778303235769272, "2079": 0.16442140936851501, "2084": 0.1358480453491211, "2... | 52868579 | Epigenetic genome modifications are thought to be important for specifying the lineage and developmental stage of cells within a multicellular organism. Here, we show that the epigenetic profile of pluripotent embryonic stem cells (ES) is distinct from that of embryonic carcinoma cells, haematopoietic stem cells (HSC) ... | Chromatin signatures of pluripotent cell lines. |
{"1011": 0.011650617234408855, "1050": 0.26146242022514343, "1052": 0.2976420819759369, "1061": 0.18573370575904846, "1164": 0.2852376699447632, "1996": 0.40351006388664246, "1999": 0.029824240133166313, "2008": 0.052318159490823746, "2011": 0.026976587250828743, "2015": 0.06795065850019455, "2024": 0.02221240475773811... | 52873726 | The Hippo pathway controls organ size and tissue homeostasis, with deregulation leading to cancer. The core Hippo components in mammals are composed of the upstream serine/threonine kinases Mst1/2, MAPK4Ks and Lats1/2. Inactivation of these upstream kinases leads to dephosphorylation, stabilization, nuclear translocati... | Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation |
{"1018": 0.02316705882549286, "1039": 0.22001366317272186, "1048": 0.5827828645706177, "1051": 0.30989447236061096, "2005": 0.19220098853111267, "2006": 0.11256109178066254, "2007": 0.015504186972975731, "2012": 0.3070250153541565, "2015": 0.823009729385376, "2020": 0.02412080205976963, "2041": 0.39433568716049194, "20... | 52874170 | CONTEXT Diagnostic lumbar punctures (LPs), commonly used to rule out meningitis, are associated with adverse events. OBJECTIVE To systematically review the evidence about diagnostic LP techniques that may decrease the risk of adverse events and the evidence about test accuracy of cerebrospinal fluid (CSF) analysis in a... | How do I perform a lumbar puncture and analyze the results to diagnose bacterial meningitis? |
{"1041": 0.17267228662967682, "1048": 0.4950772523880005, "2000": 0.2741633653640747, "2004": 0.17840765416622162, "2005": 0.056018441915512085, "2007": 0.13925230503082275, "2015": 0.1358480453491211, "2022": 0.15693697333335876, "2034": 0.25995752215385437, "2042": 0.2247048318386078, "2043": 0.20818853378295898, "20... | 52887689 | In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update thes... | Guidelines for the use and interpretation of assays for monitoring autophagy. |
{"1040": 0.22079704701900482, "1045": 0.5232481360435486, "1048": 0.3070250153541565, "2012": 0.3388410806655884, "2033": 0.22157983481884003, "2064": 0.16442140936851501, "2066": 0.0058422754518687725, "2071": 0.02792670577764511, "2079": 0.2763880789279938, "2083": 0.2516399025917053, "2109": 0.2822965085506439, "211... | 52893592 | From an organismal perspective, cancer cell populations can be considered analogous to parasites that compete with the host for essential systemic resources such as glucose. Here, we employed leukemia models and human leukemia samples to document a form of adaptive homeostasis, where malignant cells alter systemic phys... | Subversion of Systemic Glucose Metabolism as a Mechanism to Support the Growth of Leukemia Cells. |
{"1011": 0.3127557039260864, "1015": 0.13499516248703003, "1018": 0.0317181795835495, "1041": 0.2652147710323334, "1043": 0.8583967685699463, "1050": 0.6022219061851501, "1056": 0.5162794589996338, "1164": 0.5668440461158752, "2011": 0.19622190296649933, "2024": 0.14349138736724854, "2029": 0.13243216276168823, "2039":... | 52925737 | BACKGROUND Exosomes are extracellular vesicles that mediate cellular communication in health and diseases. Neutrophils could be polarized to a pro-tumor phenotype by tumor. The function of tumor-derived exosomes in neutrophil regulation remains unclear. METHODS We investigated the effects of gastric cancer cell-derived... | Tumor-derived exosomes induce N2 polarization of neutrophils to promote gastric cancer cell migration |
{"1011": 0.5833279490470886, "1035": 0.02316705882549286, "1038": 0.09938567131757736, "1039": 0.16359257698059082, "1054": 1.0001721382141113, "2000": 0.03925827145576477, "2004": 0.0058422754518687725, "2008": 0.09938567131757736, "2011": 0.4286321699619293, "2012": 0.3170322775840759, "2015": 0.6926587820053101, "20... | 52944377 | Actively transcribed regions of the genome are protected by transcription-coupled DNA repair mechanisms, including transcription-coupled homologous recombination (TC-HR). Here we used reactive oxygen species (ROS) to induce and characterize TC-HR at a transcribed locus in human cells. As canonical HR, TC-HR requires RA... | ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB |
{"1048": 0.3757305145263672, "2003": 0.2822965085506439, "2005": 0.04767346754670143, "2011": 0.36900100111961365, "2036": 0.27044451236724854, "2054": 0.02316705882549286, "2064": 0.12814582884311676, "2076": 0.08871890604496002, "2079": 0.03831886500120163, "2109": 0.3027053773403168, "2124": 0.2493593990802765, "213... | 53033275 | Autophagy is a ubiquitous catabolic process by which damaged or harmful intracellular components are delivered to the lysosomes for self-digestion and recycling. It is critical in cancer treatment. Therapy-induced autophagy predominantly acts as a pro-survival mechanism, but progressive autophagy can lead to non-apopto... | Autophagy and its potent modulators from phytochemicals in cancer treatment |
{"1011": 0.2145126610994339, "1014": 0.3824150264263153, "1019": 0.5540198087692261, "1041": 0.969535231590271, "1051": 0.5729197263717651, "1052": 0.23247487843036652, "1999": 0.21135559678077698, "2006": 0.040196798741817474, "2007": 0.0770333781838417, "2011": 0.11081436276435852, "2013": 0.41065993905067444, "2015"... | 53211308 | BACKGROUND microRNAs (miRNAs) stably exist in circulating blood and are encapsulated in extracellular vesicles such as exosomes. The aims of this study were to identify which exosomal miRNAs are highly produced from epithelial ovarian cancer (EOC) cells, to analyze whether serum miRNA can be used to discriminate patien... | Exosomal miR-99a-5p is elevated in sera of ovarian cancer patients and promotes cancer cell invasion by increasing fibronectin and vitronectin expression in neighboring peritoneal mesothelial cells |
{"1011": 0.08064348995685577, "1014": 0.04113444685935974, "1049": 0.04113444685935974, "1052": 1.0628231763839722, "2003": 0.43875885009765625, "2073": 0.15860503911972046, "2109": 0.3560888469219208, "2116": 0.5579402446746826, "2121": 0.2247048318386078, "2124": 0.12814582884311676, "2155": 1.1450434923171997, "2177... | 53302393 | Pfam is a widely used database of protein families, currently containing more than 13,000 manually curated protein families as of release 26.0. Pfam is available via servers in the UK (http://pfam.sanger.ac.uk/), the USA (http://pfam.janelia.org/) and Sweden (http://pfam.sbc.su.se/). Here, we report on changes that hav... | The Pfam protein families database. |
{"1044": 0.2561853528022766, "1052": 0.24631060659885406, "1998": 0.30558720231056213, "2000": 0.15359249711036682, "2005": 0.11081436276435852, "2007": 0.3903779089450836, "2044": 0.40871503949165344, "2060": 0.07341018319129944, "2064": 0.13499516248703003, "2076": 0.026025565341114998, "2079": 0.0606246218085289, "2... | 53779698 | INTRODUCTION Patients with symptomatic peripheral artery disease (PAD) exhibit reduced functional capacity and increased mortality due to cardiovascular disease. Although exercise has been a cornerstone for clinical treatment to improve walking capacity in patients with symptomatic PAD, its effects on cardiovascular pa... | Exercise as a therapeutic approach to improve blood pressure in patients with peripheral arterial disease: current literature and future directions. |
{"1011": 0.24171993136405945, "1015": 0.4574742913246155, "1050": 0.4537591338157654, "1051": 1.1469062566757202, "1164": 0.4002431631088257, "2003": 0.06795065850019455, "2011": 0.39367714524269104, "2012": 0.29255300760269165, "2015": 0.1485546976327896, "2028": 0.02887592278420925, "2029": 0.2881702482700348, "2050"... | 54482327 | Background/Aims: Osteoarthritis (OA) is a multifactorial disease that is associated with inflammation in joints. The purpose of the present study was to investigate the anti-inflammatory activity and mechanism of morin on human osteoarthritis chondrocytes stimulated by IL-1β. Methods: The levels of NO and PGE2 were mea... | Morin Exhibits Anti-Inflammatory Effects on IL-1β-Stimulated Human Osteoarthritis Chondrocytes by Activating the Nrf2 Signaling Pathway |
{"1020": 0.04953393340110779, "1039": 0.11865071207284927, "1044": 0.7201237678527832, "1050": 0.28670501708984375, "1052": 0.04113444685935974, "1053": 0.10379679501056671, "1999": 0.20739519596099854, "2001": 0.0038986403960734606, "2003": 0.11951763927936554, "2026": 0.3982778787612915, "2048": 0.1970241367816925, "... | 54490092 | Blood pressure variability is one of the characteristic features of hypertension in the elderly. However, its clinical significance remains to be determined. We therefore examined the impact of blood pressure variability on the development of cardiovascular events in elderly hypertensive patients. A total of 106 consec... | Impact of blood pressure variability on cardiovascular events in elderly patients with hypertension. |
{"1011": 0.04860413447022438, "1020": 0.45994341373443604, "1039": 0.04487626627087593, "1044": 0.5751199722290039, "1045": 0.5506471395492554, "1048": 0.42735910415649414, "1052": 0.41065993905067444, "1062": 0.6941232681274414, "2002": 0.2830325961112976, "2005": 0.10993985831737518, "2024": 0.1905880719423294, "2026... | 54561384 | Hematopoietic stem cells (HSCs) sustain blood formation throughout life and are the functional units of bone marrow transplantation. We show that transient expression of six transcription factors Run1t1, Hlf, Lmo2, Prdm5, Pbx1, and Zfp37 imparts multilineage transplantation potential onto otherwise committed lymphoid a... | Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors. |
{"1011": 0.33115679025650024, "1021": 0.8517522215843201, "1039": 0.9317949414253235, "1053": 0.14095009863376617, "2000": 0.7583568692207336, "2004": 0.14179791510105133, "2005": 0.12470348179340363, "2007": 0.040196798741817474, "2011": 0.32129061222076416, "2012": 0.5893046259880066, "2013": 0.10555581003427505, "20... | 54561709 | Common recommendations for cell line authentication, annotation and quality control fall short addressing genetic heterogeneity. Within the Human Toxome Project, we demonstrate that there can be marked cellular and phenotypic heterogeneity in a single batch of the human breast adenocarcinoma cell line MCF-7 obtained di... | Genetic variability in a frozen batch of MCF-7 cells invisible in routine authentication affecting cell function |
{"1015": 0.27342069149017334, "1039": 0.175953671336174, "1054": 0.7445381283760071, "1060": 0.2830325961112976, "2003": 0.03266380727291107, "2005": 0.16524957120418549, "2008": 0.040196798741817474, "2015": 0.01934296265244484, "2028": 0.04487626627087593, "2029": 0.29255300760269165, "2039": 0.4158279001712799, "204... | 54562433 | Mitochondrial transport is crucial for neuronal and axonal physiology. However, whether and how it impacts neuronal injury responses, such as neuronal survival and axon regeneration, remain largely unknown. In an established mouse model with robust axon regeneration, we show that Armcx1, a mammalian-specific gene encod... | The Mammalian-Specific Protein Armcx1 Regulates Mitochondrial Transport during Axon Regeneration |
{"1006": 0.05139094591140747, "1038": 0.4891071021556854, "1043": 0.8682814836502075, "1156": 0.7426811456680298, "1157": 0.5209306478500366, "2003": 0.14433705806732178, "2034": 0.045809537172317505, "2046": 0.1212492436170578, "2048": 0.16110190749168396, "2060": 0.07793712615966797, "2090": 0.12728634476661682, "209... | 55040297 | The term beta diversity has been used to refer to a wide variety of phenomena. Although all of these encompass some kind of compositional heterogeneity between places, many are not related to each other in any predictable way. The present two-part review aims to put the different phenomena that have been called beta di... | A diversity of beta diversities: straightening up a concept gone awry. Part 1. Defining beta diversity as a function of alpha and gamma diversity |
{"1047": 0.05417001247406006, "2005": 0.18492233753204346, "2022": 0.11168810725212097, "2029": 0.10026945173740387, "2043": 0.07159364968538284, "2048": 0.36290550231933594, "2058": 0.04767346754670143, "2062": 0.4855078160762787, "2084": 0.4891071021556854, "2111": 0.4132472574710846, "2119": 0.5534584522247314, "212... | 55128127 | The objective of the present study was to examine consumer preference and consumption behaviour with respect to the health benefits of wine for two contextually and culturally diverse consumer groups, namely Koreans and Australians. Participants were required to be wine consumers over the age of 18. Responses were coll... | A cross-cultural study of wine consumers with respect to health benefits of wine |
{"1037": 0.05046287178993225, "2003": 0.2447827309370041, "2005": 0.09406650811433792, "2015": 0.043007105588912964, "2024": 0.07793712615966797, "2037": 0.11517547070980072, "2038": 0.09850110858678818, "2046": 0.04767346754670143, "2060": 0.052318159490823746, "2064": 0.026025565341114998, "2071": 0.15275461971759796... | 56391045 | India and Israel have raised over US$35 billion by tapping into the wealth of their diaspora communities. These diaspora bonds represent a stable and cheap source of external finance, often when countries lost access to international capital markets. For diaspora investors, these bonds offer the opportunity to help the... | DIASPORA BONDS: TAPPING THE DIASPORA DURING DIFFICULT TIMES |
{"1011": 0.08603433519601822, "1014": 0.14179791510105133, "1017": 0.27712854743003845, "1018": 0.25995752215385437, "1026": 0.036437395960092545, "1038": 0.3910386264324188, "1039": 0.5893046259880066, "1041": 0.5438674688339233, "1045": 0.33115679025650024, "1050": 0.7047978043556213, "1051": 0.5427330136299133, "105... | 56486733 | BACKGROUND The purpose of this study was to explore the function and mechanism of peroxisome proliferator activated receptor agonist (PPARγ) in the toll-like receptor 2 (TLR2)/nod-like receptor with pyrin domain containing 3 (NLRP3) inflammatory corpuscle pathway of asthmatic mice. MATERIAL AND METHODS Eighteen female ... | Peroxisome Proliferator Activated Receptor gamma (PPARγ) Agonist Rosiglitazone Ameliorate Airway Inflammation by Inhibiting Toll-Like Receptor 2 (TLR2)/Nod-Like Receptor with Pyrin Domain Containing 3 (NLRP3) Inflammatory Corpuscle Activation in Asthmatic Mice |
{"1044": 0.6970458030700684, "1051": 0.5069117546081543, "2002": 0.9650808572769165, "2004": 0.4950772523880005, "2007": 0.022212404757738113, "2010": 0.03925827145576477, "2022": 0.31489628553390503, "2029": 0.25995752215385437, "2072": 0.9769153594970703, "2079": 0.07341018319129944, "2083": 0.007782140281051397, "21... | 56528795 | Liver is a vital organ with many important functions, and the maintenance of normal hepatic function is necessary for health. As an essential mechanism for maintaining cellular homeostasis, autophagy plays an important role in ensuring normal organ function. Studies have indicated that the degeneration of hepatic funct... | Omi/HtrA2 Participates in Age-Related Autophagic Deficiency in Rat Liver |
{"1018": 0.04207121208310127, "1044": 0.2749055027961731, "2007": 0.12642613053321838, "2011": 0.05786345899105072, "2029": 0.0174254160374403, "2048": 0.15526613593101501, "2050": 0.1913948506116867, "2076": 0.025073638185858727, "2078": 0.6679295301437378, "2100": 0.401551216840744, "2135": 0.40481385588645935, "2141... | 56893404 | Background Macrosomia is associated with considerable neonatal and maternal morbidity. Factors that predict macrosomia are poorly understood. The increased rate of macrosomia in the offspring of pregnant women with diabetes and in congenital hyperinsulinaemia is mediated by increased foetal insulin secretion. We asses... | Macrosomia and Hyperinsulinaemic Hypoglycaemia in Patients with Heterozygous Mutations in the HNF4A Gene |
{"1011": 0.15359249711036682, "2001": 0.02412080205976963, "2003": 0.2493593990802765, "2012": 0.2561853528022766, "2019": 0.1913948506116867, "2040": 0.12556517124176025, "2041": 0.37304413318634033, "2043": 0.1693800985813141, "2047": 0.08603433519601822, "2051": 0.13670019805431366, "2073": 0.13071982562541962, "207... | 57121667 | The ART-adherence club model described here provides patient-friendly access to antiretroviral therapy (ART) for clinically stable patients. It reduces the burden that stable patients place on healthcare facilities, increasing clinical human resources for new patients, and those clinically unstable and at risk of faili... | ART adherence clubs: A long-term retention strategy for clinically stable patients receiving antiretroviral therapy |
{"1017": 0.08603433519601822, "1019": 0.38574060797691345, "1042": 0.8212929964065552, "2003": 0.29109421372413635, "2011": 0.055094651877880096, "2012": 0.21135559678077698, "2026": 0.7426811456680298, "2029": 0.25088030099868774, "2033": 0.07068414986133575, "2058": 0.3416208028793335, "2078": 0.2881702482700348, "20... | 57574395 | Defective brain hormonal signaling has been associated with Alzheimer's disease (AD), a disorder characterized by synapse and memory failure. Irisin is an exercise-induced myokine released on cleavage of the membrane-bound precursor protein fibronectin type III domain-containing protein 5 (FNDC5), also expressed in the... | Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models |
{"1039": 0.27564704418182373, "1998": 0.22782009840011597, "2006": 0.37707099318504333, "2020": 0.11430477350950241, "2025": 0.1808556467294693, "2045": 0.014542185701429844, "2051": 0.1332872211933136, "2060": 0.15860503911972046, "2062": 0.17922431230545044, "2071": 0.10379679501056671, "2076": 0.36290550231933594, "... | 57762078 | Background Compared to other European countries, Sweden's yearly sick leave expenditures are moderate. Common mental disorders (CMD) are important causes of sick leave, affecting 10-15% of the adult population. A Swedish register based study indicates that antidepressant therapy for patients on long-term sick leave for... | Influence of antidepressant therapy on sick leave in primary care: ADAS, a comparative observational study |
{"1011": 0.0842406153678894, "1016": 0.4831010699272156, "1017": 0.0317181795835495, "1039": 0.2689530849456787, "1040": 0.04487626627087593, "1043": 0.31560876965522766, "1059": 0.5903874635696411, "1060": 0.2696990668773651, "1156": 0.3325583338737488, "2011": 0.31489628553390503, "2026": 0.5215105414390564, "2029": ... | 57783564 | Caudal-related homeobox transcription factor 2 (CDX2), an intestine-specific nuclear transcription factor, has been strongly implicated in the tumourigenesis of various human cancers. However, the functional role of CDX2 in the development and progression of colorectal cancer (CRC) is not well known. In this study, CDX... | CDX2 inhibits the proliferation and tumor formation of colon cancer cells by suppressing Wnt/β-catenin signaling via transactivation of GSK-3β and Axin2 expression |
{"1018": 0.2394166737794876, "1041": 0.6853039860725403, "1051": 0.10467668622732162, "1052": 0.2674594223499298, "1156": 0.3547199070453644, "2011": 0.4938860833644867, "2029": 0.23092569410800934, "2043": 0.055094651877880096, "2063": 0.9951307773590088, "2064": 0.23787821829319, "2079": 0.35745587944984436, "2083": ... | 58006489 | Whether sensory nerve can sense bone density or metabolic activity to control bone homeostasis is unknown. Here we found prostaglandin E2 (PGE2) secreted by osteoblastic cells activates PGE2 receptor 4 (EP4) in sensory nerves to regulate bone formation by inhibiting sympathetic activity through the central nervous syst... | Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis |
{"1004": 0.06429435312747955, "1016": 0.05046287178993225, "1017": 0.21372433006763458, "1041": 0.2184450328350067, "1054": 0.35677260160446167, "1998": 0.5685047507286072, "2000": 0.18329764902591705, "2001": 0.23556606471538544, "2011": 0.2576959431171417, "2018": 0.02316705882549286, "2020": 0.07884006202220917, "20... | 58050905 | The World Health Organisation has declared the period 2000 to 2010 the Bone and Joint Decade. This is indeed timely and appropriate. Hundreds of millions of people in the world today are beset with a host of disabilities caused by trauma, ageing and degeneration and other affections of the musculo-skeletal system. With... | The Bone and Joint Decade 2000-2010. |
{"1003": 0.12470348179340363, "1018": 0.08692999184131622, "2000": 0.11168810725212097, "2001": 0.036437395960092545, "2005": 0.014542185701429844, "2013": 0.10026945173740387, "2015": 0.16110190749168396, "2020": 0.15359249711036682, "2055": 0.04394211992621422, "2061": 0.5016035437583923, "2071": 0.17020416259765625,... | 58564850 | Background We aimed to determine the prevalence and gap in use of mental health services for late-life depression in four European regions (Western Europe, Scandinavia, Southern Europe and Central and Eastern Europe) and explore socio-demographic, social and health-related factors associated with it. Methods We conduct... | Prevalence of late-life depression and gap in mental health service use across European regions. |
{"1011": 0.34922540187835693, "1013": 0.10993985831737518, "1014": 0.08692999184131622, "1039": 0.6139179468154907, "1042": 0.5197699069976807, "1045": 0.5174443125724792, "1052": 0.8425432443618774, "1055": 0.23092569410800934, "1058": 0.5995445251464844, "1997": 0.31845372915267944, "1999": 1.1561684608459473, "2004"... | 59453688 | An Al/methyl-red/p-InP solar cell was fabricated via solution-processing method and was characterized by using current-voltage (I-V) and capacitance-voltage-frequency (C-V-f) measurements at room temperature. From dark I-V characteristics, the values of ideality factor and barrier height of the device were calculated a... | Impedance and Interface Properties of Al/Methyl-Red/p-InP Solar Cell |
{"1016": 0.06977381557226181, "1039": 0.33115679025650024, "1053": 0.151916041970253, "1054": 0.3381449282169342, "1998": 0.26820653676986694, "2000": 0.10026945173740387, "2003": 0.030771657824516296, "2007": 0.037378571927547455, "2015": 0.0317181795835495, "2023": 0.022212404757738113, "2047": 0.6170841455459595, "2... | 60206680 | Abstract In this article we discuss our experience designing and implementing a statistical computing language. In developing this new language, we sought to combine what we felt were useful features from two existing computer languages. We feel that the new language provides advantages in the areas of portability, com... | R: A Language for Data Analysis and Graphics |
{"1017": 0.4374985992908478, "1020": 0.175953671336174, "1054": 0.3683255612850189, "1060": 0.4462870955467224, "1996": 0.19220098853111267, "1999": 0.19862671196460724, "2003": 0.3423145115375519, "2006": 0.1734936386346817, "2023": 0.10026945173740387, "2029": 0.02412080205976963, "2042": 0.11951763927936554, "2064":... | 60515890 | " The Mouse Brain in Stereotaxic Coordinates" is the most widely used and cited atlas of the mouse brain in print. It provides researchers and students with both accurate stereotaxic coordinates for laboratory use, and detailed delineations and indexing of structures for reference. The accompanying DVD provides drawing... | The Mouse Brain in Stereotaxic Coordinates |
{"999": 0.016465263441205025, "1016": 0.5410289764404297, "1043": 1.0920805931091309, "1054": 1.0628231763839722, "2003": 0.3810817003250122, "2005": 0.12384103983640671, "2040": 0.31132611632347107, "2047": 0.08961215615272522, "2117": 0.04860413447022438, "2129": 0.0354953333735466, "2182": 0.2852376699447632, "2186"... | 61050894 | ggplot2: Elegant Graphics for Data Analysis is a new addition to the UseR! series by Springer, probably the fastest expanding source of resources for computational statistics at the current moment. The books in this series are all linked with R, either presenting a new package developed by the own authors of the book o... | ggplot2: Elegant Graphics for Data Analysis |
{"1049": 0.4873090982437134, "1058": 0.08064348995685577, "1999": 0.006812678650021553, "2000": 0.037378571927547455, "2003": 0.3374483287334442, "2004": 0.2659635543823242, "2005": 0.18167030811309814, "2006": 0.037378571927547455, "2025": 0.06703783571720123, "2051": 0.17020416259765625, "2053": 0.35745587944984436, ... | 63858430 | multiple imputation for nonresponse in surveys is available in our book collection an online access to it is set as public so you can download it instantly. Our book servers hosts in multiple locations, allowing you to get the most less latency time to download any of our books like this one. Merely said, the multiple ... | Multiple Imputation For Nonresponse In Surveys |
{"1011": 0.11081436276435852, "1018": 0.3381449282169342, "1039": 0.5778634548187256, "1040": 0.8500841856002808, "1041": 0.6931471824645996, "1048": 0.36697331070899963, "1056": 0.6064908504486084, "2002": 0.619189441204071, "2005": 0.16524957120418549, "2011": 0.5324648022651672, "2029": 0.06246116757392883, "2038": ... | 67045088 | Post-translational modification of chemokines mediated by the dipeptidyl peptidase DPP4 (CD26) has been shown to negatively regulate lymphocyte trafficking, and its inhibition enhances T cell migration and tumor immunity by preserving functional chemokine CXCL10. By extending those initial findings to pre-clinical mode... | Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth |
{"1011": 0.09228714555501938, "1015": 0.04207121208310127, "1040": 0.5450005531311035, "1041": 0.0038986403960734606, "1043": 0.9115922451019287, "1056": 0.9340999722480774, "2003": 0.31204116344451904, "2011": 0.21372433006763458, "2015": 0.0038986403960734606, "2029": 0.05970508232712746, "2039": 0.12642613053321838,... | 67787658 | Glioblastoma multiforme (GBM) is a fatal malignancy of the central nervous system, commonly associated with chemoresistance. The alkylating agent Temozolomide (TMZ) is the front-line chemotherapeutic agent and has undergone intense studies on resistance. These studies reported on mismatch repair gene upregulation, ABC-... | Cycling Quiescence in Temozolomide Resistant Glioblastoma Cells Is Partly Explained by microRNA-93 and -193-Mediated Decrease of Cyclin D |
{"1011": 0.15693697333335876, "1014": 0.29400965571403503, "1020": 0.03266380727291107, "1039": 0.07612881064414978, "1043": 0.6075552701950073, "1047": 0.5301685929298401, "1048": 0.2247048318386078, "1052": 0.5844172835350037, "1053": 0.5517725944519043, "2004": 0.045809537172317505, "2012": 0.4950772523880005, "2019... | 68317730 | Objectives Corin, an atrial natriuretic peptide-converting enzyme, has been found to promote trophoblast invasion and spiral artery remodeling. Reduced maternal plasma atrial natriuretic peptide (ANP) levels and elevated corin levels have been reported in pregnancies complicated by PE. The aim of this study was to inve... | Longitudinal changes in maternal corin and mid-regional proatrial natriuretic peptide in women at risk of pre-eclampsia |
{"1016": 0.6674286723136902, "1055": 0.3910386264324188, "1998": 0.030771657824516296, "2013": 0.030771657824516296, "2034": 0.2470736801624298, "2047": 0.5069117546081543, "2048": 0.4041621685028076, "2086": 0.0038986403960734606, "2116": 0.38308101892471313, "2117": 1.0874829292297363, "2128": 0.2145126610994339, "21... | 69045262 | The reorganized and newly revised "Children's Exercise Physiology, Second Edition, " presents the most up-to-date research, methodology, and approaches related to children's physiologic responses to exercise. The book examines not only the current major issues that separate children from adults, but also the underlying... | Children's Exercise Physiology |
{"1011": 0.1064341589808464, "1023": 0.1221139207482338, "1039": 0.05417001247406006, "1041": 0.2711893916130066, "2000": 0.08603433519601822, "2004": 0.0029254043474793434, "2050": 0.21765978634357452, "2051": 0.44566190242767334, "2054": 0.03360854089260101, "2093": 0.026025565341114998, "2109": 0.05970508232712746, ... | 70439309 | 1. Cost-Effectiveness Analysis as a Guide to Resource Allocation in Health: Roles and Limitations 2. Theoretical Foundations of Cost-Effectiveness Analysis 3. Framing and Designing the Cost-Effectiveness Analysis 4. Identifying and Valuing Outcomes 5. Assessing the Effectiveness of Health Interventions 6. Estimating Co... | Cost-effectiveness in health and medicine |
{"1045": 0.18492233753204346, "2001": 0.28743788599967957, "2043": 0.3949938118457794, "2072": 0.037378571927547455, "2076": 0.6872705817222595, "2077": 0.29109421372413635, "2079": 0.014542185701429844, "2090": 0.28963330388069153, "2095": 0.34577593207359314, "2096": 0.10906458646059036, "2104": 0.3662964701652527, "... | 70455704 | As women of childbearing age have become heavier, the trade-off between maternal and child health created by variation in gestational weight gain has become more difficult to reconcile. Weight Gain During Pregnancy responds to the need for a reexamination of the 1990 Institute of Medicine guidelines for weight gain dur... | Weight gain during pregnancy: reexamining the guidelines. |
{"1016": 0.04207121208310127, "1037": 0.06795065850019455, "1051": 0.16110190749168396, "1053": 0.04113444685935974, "2000": 0.11430477350950241, "2004": 0.006812678650021553, "2009": 0.29981520771980286, "2012": 0.1994270235300064, "2019": 0.4709797203540802, "2034": 0.09228714555501938, "2043": 0.13925230503082275, "... | 70516463 | Human beings, make errors Healthcare Services is a complex industry prone to accidents. The IOM Report [1] points out that some systems are more prone to accidents than others. When a system fails there are often multiple faults. In healthcare,human errors are the greatest contributors to accidents,however when human e... | To err is human. Building a safer health system |
{"1023": 0.1930064558982849, "1048": 0.03266380727291107, "1052": 0.3949938118457794, "1054": 0.7239188551902771, "1055": 0.07884006202220917, "2007": 0.2983669638633728, "2015": 0.46363574266433716, "2026": 0.4974553883075714, "2035": 0.1994270235300064, "2039": 0.3134697377681732, "2050": 0.06886265426874161, "2086":... | 70633421 | The incidence of malignant neoplasms among 11 483 male and 34 618 female individuals with rheumatoid arthritis was studied using two separate nationwide data registers covering the whole Finnish population: the Social Insurance Institution9s Population Data Register, which includes information on medication for certain... | Excess risk of lymphomas, leukemia and myeloma in patients with rheumatoid arthritis |
{"1016": 0.4132472574710846, "1997": 0.2652147710323334, "1998": 0.1930064558982849, "1999": 0.016465263441205025, "2002": 0.07159364968538284, "2003": 0.09228714555501938, "2004": 0.055094651877880096, "2010": 0.5450005531311035, "2019": 0.004870930220931768, "2024": 0.00875066313892603, "2042": 0.23479416966438293, "... | 70704988 | Advanced Human Nutrition, Second Edition provides an in-depth overview of the human body and details why nutrients are important from a biochemical, physiological, and molecular perspective. Figures help illustrate the content and bring the meaning to life to enhance the reader's understanding. Complex pathways, for ex... | Advanced Human Nutrition |
{"1011": 0.2026219218969345, "1041": 0.22548456490039825, "2000": 0.09672962874174118, "2011": 0.16110190749168396, "2029": 0.07431721687316895, "2203": 1.0229004621505737, "2207": 0.7951818704605103, "2265": 0.006812678650021553, "2334": 0.755608320236206, "2470": 0.45623743534088135, "2491": 0.1619328260421753, "2537... | 70895396 | Introduction. Methods To Study Endothelium-Dependent Responses. Endothelium-Derived Relaxing Factor. Physiological Actions. Other Relaxing Substances Released By the Endothelium. Production of Contracting Agents. Local Regulation of Endothelium-Dependent Responses. Neurohumoral Regulation. Heterogeneity and Chronic Mod... | The Endothelium: Modulator of Cardiovascular Function |
{"1014": 0.1751343309879303, "1015": 0.13499516248703003, "1016": 0.672426164150238, "1020": 0.034552380442619324, "1039": 0.6170841455459595, "1044": 0.4734157919883728, "1052": 0.3560888469219208, "1056": 0.6011518239974976, "1058": 0.8509185314178467, "1081": 0.42799583077430725, "1999": 0.11081436276435852, "2007":... | 71341302 | Abstract Objective Our previous 6-month, randomized study demonstrated the beneficial effect of a vegetarian (V) compared to a conventional diet (C) with similar caloric restriction on cardiovascular risk factors for patients with type 2 diabetes (T2D), namely increased insulin sensitivity, reduced body weight, reduced... | Vegetarian vs. conventional diabetic diet – A 1-year follow-up |
{"1018": 0.04487626627087593, "1044": 0.1808556467294693, "1046": 0.27934664487838745, "1057": 0.7665573358535767, "1998": 0.19541899859905243, "2007": 0.23787821829319, "2038": 0.22704219818115234, "2058": 0.0913962796330452, "2084": 0.2539152204990387, "2110": 0.33325836062431335, "2116": 0.14518201351165771, "2152":... | 71625969 | Abstract Background: For the past 20 years numerous epidemiological studies have correlated the consumption of alcohol and a variety of disease states: overall mortality, arteriosclerotic vascular diseases, hypertension, cancers, peptic ulcer, respiratory infections, gall stones, kidney stones, age-related macular dege... | Alcohol, wine, and health |
{"1003": 0.20501139760017395, "1045": 0.4617912769317627, "1997": 0.015504186972975731, "2001": 0.27044451236724854, "2018": 0.24859806895256042, "2020": 0.3777405619621277, "2025": 0.28670501708984375, "2028": 0.23247487843036652, "2034": 0.5596157908439636, "2042": 0.45251765847206116, "2043": 0.2741633653640747, "20... | 71628189 | Abstract In order to develop a program for prevention of unwanted pregnancies, we conducted a survey of contraceptive practices and reasons for contraceptive failures of 1520 women seeking abortion at eight large hospitals in Zheng Zhou City, Henan Province, P.R. China, during the period from March 1996 to May 1996. Th... | Contraceptive practices of women requesting termination of pregnancy : A study from China |
{"1037": 0.12642613053321838, "1042": 0.0009760859538801014, "1996": 0.026976587250828743, "1997": 0.06795065850019455, "2001": 0.2478361576795578, "2006": 0.6369074583053589, "2007": 0.31560876965522766, "2015": 0.00875066313892603, "2020": 0.5069117546081543, "2024": 0.15023678541183472, "2037": 0.5347557663917542, "... | 72180760 | To determine physicians' perceptions of the effects that the companions of cancer patients have on physician-patient communication, semistructured interviews were conducted with 12 oncologists (6 medical, 4 surgical, and 2 radiation) from a total population of 21 oncologists. The physicians estimated that threefourths ... | Oncologists' perceptions of the effects of cancer patients' companions on physician-patient interactions |
{"1016": 0.24171993136405945, "1059": 0.014542185701429844, "1996": 0.1229778528213501, "2001": 0.22157983481884003, "2006": 0.43053874373435974, "2010": 0.0752234235405922, "2011": 0.040196798741817474, "2019": 0.43434104323387146, "2029": 0.11430477350950241, "2034": 0.07793712615966797, "2040": 0.5707147121429443, "... | 72372925 | There has never been a book on headache that came close to that of the late Harold Wolff. The second edition was published 10 years ago; it was and is a masterpiece of writing, an exhaustive yet engrossing delineation of Wolff's long study and understanding of headache. The new edition, revised by Dalessio, serves to b... | Wolff's Headache and Other Head Pain. |
{"1018": 0.15860503911972046, "1037": 0.010684899985790253, "1042": 0.1485546976327896, "1050": 0.1677299439907074, "2001": 0.00875066313892603, "2020": 0.20818853378295898, "2022": 0.014542185701429844, "2047": 0.0029254043474793434, "2054": 0.09584271162748337, "2055": 0.29036402702331543, "2073": 0.09938567131757736... | 72580164 | Background: Family doctors play an important role in the health care for terminal ill and patients. The current level of palliative care in Germany is strongly criticised, however, empirical data is scare, particularly with respect to family doctors. Methods: Therefore, the attitudes of family doctors (sample: n= 257) ... | Ansichten von Hausärzten zur Versorgung von unheilbar kranken Patienten am Lebensende - Ergebnisse einer Befragung in Niedersachsen |
{"1011": 0.18492233753204346, "1020": 0.01934296265244484, "1038": 0.3870677351951599, "1039": 0.7969439625740051, "1044": 0.04860413447022438, "1045": 0.04674193635582924, "1052": 0.5313173532485962, "1998": 0.07884006202220917, "2004": 0.5968599319458008, "2005": 0.04860413447022438, "2012": 0.5461324453353882, "2029... | 72933407 | ContextSeveral novel risk factors for atherosclerosis have recently been proposed, but few comparative data exist to guide clinical use of these emerging biomarkers. ObjectiveTo compare the predictive value of 11 lipid and nonlipid biomarkers as risk factors for development of symptomatic peripheral arterial disease (P... | Novel Risk Factors for Systemic Atherosclerosis: A Comparison of C-Reactive Protein, Fibrinogen, Homocysteine, Lipoprotein(a), and Standard Cholesterol Screening as Predictors of Peripheral Arterial Disease |
{"1016": 0.1602703034877777, "1997": 0.401551216840744, "2001": 0.31845372915267944, "2028": 0.02316705882549286, "2034": 0.40546512603759766, "2042": 0.27342069149017334, "2043": 0.29619070887565613, "2046": 0.3388410806655884, "2048": 0.5313173532485962, "2060": 0.23710809648036957, "2077": 0.2247048318386078, "2095"... | 73136607 | THE use of formal devices for assessing function is becoming standard in agencies serving the elderly. In the Gerontological Society's recent contract study on functional assessment (Howell, 1968), a large assortment of rating scales, checklists, and other techniques in use in applied settings was easily assembled. The... | Assessment of older people: Self-maintaining and instrumental activities of daily living. |
{"1009": 0.09495500475168228, "1013": 0.07159364968538284, "1014": 0.5209306478500366, "1015": 0.42544642090797424, "1016": 0.3601844012737274, "1018": 0.2018241584300995, "1019": 0.34922540187835693, "1020": 0.5057345628738403, "1021": 0.4196864068508148, "1022": 0.20739519596099854, "1043": 0.9037119746208191, "1044"... | 73323408 | In February 2015 the National Institute for Health and Care Excellence (NICE) published new guidance (NG3) on the management of diabetes in pregnancy. Care teams need to be aware of this guidance and implement its recommendations. These include preconception care with target HbA1c 48 mmol/mol. Women at risk of gestatio... | Diabetes in pregnancy: management of diabetes and its complications from preconception to the postnatal period (NG3) |
{"1018": 0.41647201776504517, "1019": 0.02792670577764511, "1020": 0.06337817758321762, "1044": 0.22937409579753876, "1056": 0.0913962796330452, "1998": 0.09850110858678818, "2000": 0.037378571927547455, "2001": 0.06612417846918106, "2007": 0.3346569836139679, "2015": 0.6170841455459595, "2018": 0.03360854089260101, "2... | 73473433 | BACKGROUND Over the past 20 years the prevalence of child and adolescent mental disorders in high-income countries has not changed despite increased investment in mental health services. Insufficient contact with mental health services may be a contributing factor; however, it is not known what proportion of children h... | Mental health difficulties across childhood and mental health service use: findings from a longitudinal population-based study. |
{"1014": 0.09938567131757736, "1059": 0.3127557039260864, "1997": 0.05046287178993225, "2001": 0.13670019805431366, "2013": 0.18329764902591705, "2018": 0.07884006202220917, "2020": 0.14518201351165771, "2038": 0.055094651877880096, "2042": 0.034552380442619324, "2043": 0.1808556467294693, "2058": 0.2622140049934387, "... | 74137632 | This paper examines the potential impact of changes in medical care on changing population health in Lithuania, Hungary and Romania, with west Germany included for comparison. We used the concept of deaths from certain causes that should not occur in the presence of timely and effective health care (amenable mortality)... | Rembrandt Scholz |
{"1011": 0.16690383851528168, "1045": 0.38041436672210693, "1050": 0.23864774405956268, "1055": 0.41840189695358276, "1057": 0.6425731778144836, "1996": 0.045809537172317505, "2009": 0.006812678650021553, "2015": 0.24859806895256042, "2029": 0.15442965924739838, "2040": 0.11778303235769272, "2072": 0.4462870955467224, ... | 74701974 | The Women's Interagency HIV Study comprises the largest U.S. cohort to date of human immunodeficiency virus (HIV)-seropositive women (N = 2,058) with a comparison cohort of seronegative women (N = 568). The methodology, training, and quality assurance activities employed are described. The study pop | The Women's Interagency HIV Study |
{"1017": 0.10467668622732162, "1043": 0.07431721687316895, "1044": 0.5232481360435486, "1055": 0.46302130818367004, "1057": 0.09672962874174118, "2001": 0.0913962796330452, "2003": 0.02792670577764511, "2007": 0.14686977863311768, "2015": 1.0735615491867065, "2043": 0.23633737862110138, "2045": 0.07793712615966797, "20... | 75636923 | Metabolic syndrome is diagnosed when three or more of the following criteria are met: abdominal obesity (waist circumference more than 102 cm in men and 88 cm in women); hypertriglyceridemia of 150 mg/dl or above; a high-density lipoprotein (HDL) cholesterol level less than 40 mg/dl in men or 50 mg/dl in women; blood p... | Prevalence of the Metabolic Syndrome Among Us Adults: Findings From the Third National Health and Nutrition Examination Survey |
{"1003": 0.04674193635582924, "1047": 0.08154398202896118, "1050": 0.28082266449928284, "1052": 0.19862671196460724, "1058": 0.0009760859538801014, "2001": 0.06246116757392883, "2004": 0.9155091643333435, "2005": 0.026976587250828743, "2006": 0.052318159490823746, "2007": 0.21293537318706512, "2012": 0.1627630442380905... | 76415938 | As more is learned about the development of cervical cancer, the value of annual Pap smear screening for all women is being questioned. This study was conducted to investigate whether women at higher risk for the development of cervical cancer could be identified by testing for the presence of human papillomavirus (HPV... | Baseline cytology, human papillomavirus testing, and risk for cervical neoplasia: A 10-year cohort analysis |
{"1014": 0.35060185194015503, "1015": 0.48068851232528687, "1016": 0.39762192964553833, "1039": 0.11256109178066254, "1040": 0.5729197263717651, "1042": 0.36290550231933594, "1043": 0.7737906575202942, "1044": 0.15777134895324707, "1052": 0.24631060659885406, "2001": 0.026976587250828743, "2007": 0.04487626627087593, "... | 76463821 | Preconception care (PCC) and strict periconceptional glycemic control are both used to minimize the risk of congenital birth defects in offspring of women with type 1 or type 2 diabetes mellitus (DM). These malformations are ascribed in large measure to poor periconceptional control. This study evaluated PCC by a meta-... | Preconception Care and the Risk of Congenital Anomalies in the Offspring of Women With Diabetes Mellitus: A Meta-Analysis |
{"1005": 0.23247487843036652, "1048": 0.5393219590187073, "1055": 0.5756692886352539, "2001": 0.45499902963638306, "2007": 0.2539152204990387, "2014": 0.6430866718292236, "2016": 0.3910386264324188, "2018": 0.27564704418182373, "2020": 0.14095009863376617, "2022": 1.0546929836273193, "2031": 0.00875066313892603, "2038"... | 76776022 | Abstract A woman, now 59 has been followed for 13 years with several manifestations of Behcet's disease. These were aphthous stomatitis, genital ulcers, uveitis causing blindness, recurrent erythema nodosum, and synovitis. In 1970 a poorly differentiated diffuse lymphocytic lymphoma appeared and was treated with radiot... | Behçet's disease associated with a lymphoproliferative disorder, mixed cryoglobulinemia, and an immune complex mediated vasculitis. |
{"1041": 0.43434104323387146, "1997": 0.12470348179340363, "2000": 0.24171993136405945, "2001": 0.0354953333735466, "2005": 0.04207121208310127, "2007": 0.10379679501056671, "2015": 0.0038986403960734606, "2020": 0.040196798741817474, "2022": 0.7454653382301331, "2037": 0.11517547070980072, "2045": 0.10993985831737518,... | 77971703 | BACKGROUND Due to demographic changes with an increasing number of older people with chronic illness and multimorbidity palliative care for geriatric patients has become increasingly important. The aim of this study was to explore the perspective of bereaved relatives with regard to their experiences and expectations c... | Older People at the End of Life: Delivery of Care and Needs for Improvement from the Perspective of Bereaved Relatives |
{"1003": 0.41840189695358276, "1014": 0.39893341064453125, "1040": 0.09938567131757736, "1041": 0.3750596046447754, "1052": 0.5381823778152466, "1053": 0.1693800985813141, "1058": 0.4337083101272583, "1997": 0.12384103983640671, "2000": 0.11517547070980072, "2001": 0.10818854719400406, "2012": 0.3930181860923767, "2019... | 79231308 | as compared with 103 (8.2 percent) in the control group; the Kaplan-Meier estimates of the likelihood of freedom from deep-vein thrombosis or pulmonary embolism at 90 days were 94.1 percent (95 percent confidence interval, 92.5 to 95.4 percent) and 90.6 percent (95 percent confidence interval, 88.7 to 92.2 percent), re... | Role of Computerized Physician Order Entry Systems in Facilitating Medication Errors |
{"1011": 0.3683255612850189, "1038": 0.41840189695358276, "1051": 0.08603433519601822, "1156": 0.684319257736206, "2015": 0.17267228662967682, "2062": 0.0058422754518687725, "2079": 0.09228714555501938, "2091": 0.3464667797088623, "2109": 0.07250232994556427, "2110": 0.3269403576850891, "2163": 0.24171993136405945, "22... | 79336156 | In this review, we consider the potential functional role of beta-band oscillations, which at present is not yet well understood. We discuss evidence from recent studies on top-down mechanisms involved in cognitive processing, on the motor system and on the pathophysiology of movement disorders that suggest a unifying ... | Beta-band oscillations--signalling the status quo? |
{"1009": 0.17020416259765625, "1011": 0.2231435477733612, "1018": 0.022212404757738113, "1019": 0.11517547070980072, "1020": 0.13157635927200317, "1044": 0.42735910415649414, "1048": 0.29036402702331543, "1052": 0.3777405619621277, "1053": 1.057410478591919, "1054": 0.7314660549163818, "1056": 1.0409941673278809, "2003... | 79696454 | 3016Background: T cell-based bispecific agents have shown activity in hematologic cancers, but solid tumor efficacy remains elusive. IMCgp100 is a bispecific biologic comprising an affinityenhanced TCR specific for gp100 and an anti-CD3 scFV. In vitro, IMCgp100 binds gp100+ melanoma cells causing redirection of cytotox... | Safety, pharmacokinetics and efficacy of IMCgp100, a first-in-class soluble TCR-antiCD3 bispecific t cell redirector with solid tumour activity: Results from the FIH study in melanoma. |
{"1075": 0.009718249551951885, "2001": 0.3982778787612915, "2003": 0.13414156436920166, "2013": 0.1011524572968483, "2015": 0.05046287178993225, "2020": 0.4574742913246155, "2040": 0.20818853378295898, "2042": 0.30558720231056213, "2046": 0.2409527748823166, "2054": 0.22392450273036957, "2055": 0.14264501631259918, "20... | 80109277 | © Joanna Moncrieff 2013. All rights reserved. A challenging reappraisal of the history of antipsychotics, revealing how they were transformed from neurological poisons into magical cures, their benefits exaggerated and their toxic effects minimized or ignored. | The Bitterest Pills: The Troubling Story of Antipsychotic Drugs |
{"1011": 0.14602625370025635, "1020": 0.3005385100841522, "1021": 0.025073638185858727, "1022": 0.10731173306703568, "1041": 0.5517725944519043, "1048": 0.5069117546081543, "1056": 0.49982786178588867, "1597": 0.33605360984802246, "2001": 0.11604541540145874, "2004": 0.619189441204071, "2007": 0.3325583338737488, "2011... | 80522346 | We studied the influence of patient, leukaemia and treatment characteristics on the kinetics of Minimal Residual Disease (MRD) clearance in children with lymphoblastic leukaemia treated using an intensive risk stratified approach. UK MRC protocol ALL97 (1997–1999), and its amended version ALL 97/99 (1999–2002), compare... | Variables Affecting Kinetics of Minimal Residual Disease Clearance in Children with Lymphoblastic Leukaemia; Results of the United Kingdom Medical Research Council (UK MRC) Protocols ALL97, ALL97/99 and ALL2003. |
{"1020": 0.11430477350950241, "1042": 0.22782009840011597, "1048": 0.06154331564903259, "1050": 0.10731173306703568, "1052": 0.14349138736724854, "1057": 0.7674643993377686, "1997": 0.4462870955467224, "1999": 0.4831010699272156, "2013": 0.025073638185858727, "2015": 0.11343330889940262, "2024": 0.022212404757738113, "... | 81498132 | Chromosome numbers from meiotic studies have been reported for the following species ofUtricularia: U. aurea Lour. (n=21);U. baouleënsis A. Chev. (n=10);U. caerulea L. (n=20);U. inflexa var.stellaris (Linn.f.) P. Taylor (n=21);U. minutissima Vahl (n=8);U. scandens Benj. (n=6, 7); andU. stricticaulis Stapf (n=7). There ... | Chromosome numbers in certain Indian species ofUtricularia L. (Lentibulariaceae) |
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