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0.422297 | e252e392bd104fe28c44c20d0a0493f8 |
(A) Schematic illustration of the therapeutic strategy for melanoma based on HA@BCN. (B) Live/dead staining of B16F10 cells in different groups. (C) Growth of tumor volume in different treatment groups. (D) Digital photographs of skin regeneration during the repair period in different groups. (Adapted with permission ... | PMC10020212 | fbioe-11-1141631-g001.jpg |
0.437059 | 092bd353e00d40ad82baaa075a502d00 |
(A) Schematic illustration of the therapeutic strategy for bacterial infection based on Nb2C@TP. (B) SEM images of biofilm-resistance performance in different groups. (C) TEM images of antibacterial performance in different groups. (Adapted with permission from Yang et al., 2021. Copyright 2021 American Chemical Socie... | PMC10020212 | fbioe-11-1141631-g002.jpg |
0.451916 | eddd24edf7c047908c54580f8dc70815 |
(A) Schematic illustration of release and activation of SN38-Nif based on ZrC@prodrug. (B) Drug release percentage with and without irradiation. (C) Relative cell viability of SMMC-7721 in different groups. (D) Growth of tumor volume in different treatment groups. (E) Digital photographs of tumor after treatments in d... | PMC10020212 | fbioe-11-1141631-g003.jpg |
0.428708 | 93ca41a4a7914dfc90c849d76a844551 |
(A) Schematic illustration of fabrication of FePSe3@APP@CCM and the strategy of combined PTT immunotherapy. (B) Schematic illustration of DC maturation during the treatment. (C) Flow cytometry analysis of DC maturation in different groups. (Adapted with permission from Fang et al., 2021. Copyright 2020 Wiley-VCH). | PMC10020212 | fbioe-11-1141631-g004.jpg |
0.379507 | 6c712775ee0841c9995f6bf37d2a4be7 |
(A) SEM images of the interface between Ti3C2TX films and DRG neurons. (B) SEM images of the interface between Ti3C2TX flakes and DRG neurons. (C) Illustration of Ti3C2TX film-mediated DRG electrical activity modulation. (D) Illustration of Ti3C2TX flake-mediated DRG electrical activity modulation. (E) Illustration of... | PMC10020212 | fbioe-11-1141631-g005.jpg |
0.494144 | d8295f049c2d451b98457d5de8bd0959 |
(A) Schematic illustration of the therapeutic strategy for IUA prevention based on CUP/PT. (B) Photothermal property of PT and CUP/PT under 1064-nm laser irradiation. (C) Shape recovery of CUP/PT at different time after irradiation on a desk (I), underneath the skin (II), and inside the isolated uterine lumen of rat (... | PMC10020212 | fbioe-11-1141631-g006.jpg |
0.479552 | cf67d0df9ab849769d73b613821180d2 |
(A) Schematic illustration of photothermal-mediated cellular uptake of BP-HAS-PTX. (B) CLSM images of U87MG cells incubated with PBS (I), BP-HAS-PTX without laser irradiation (II), and BP-HAS-PTX with laser irradiation (III), respectively. (C) Mean FITC fluorescence intensity of U87MG cells in different groups. (Adapt... | PMC10020212 | fbioe-11-1141631-g007.jpg |
0.407515 | e1c4e8f9809e4db4bc160e801d564c8a |
(A) Schematic illustration of fabrication of Ti3C2-DOX and therapeutic strategy of based on Ti3C2-DOX. (B) Absorbance of DCPF in different groups. (C) CLSM images of HCT-116c cells incubated with Ti3C2-DOX after irradiation. (Adapted with permission from Liu et al., 2017. Copyright 2017 American Chemical Society). (D)... | PMC10020212 | fbioe-11-1141631-g008.jpg |
0.450446 | d895bbd11a7c4d4cad876f5a605b45f9 | Hypoxia induces ULK1-related autophagy and mitochondrial Lon in cancer cells.A HCT-15 cells were exposed to hypoxia (1% O2) for 24 h or CoCl2 (200 µM) for 16 h and the collected lysates were immunoblotted against the mitophagy signaling using indicated antibodies. GAPDH as the loading control. B HCT-15 cells were expos... | PMC10020552 | 41419_2023_5723_Fig1_HTML.jpg |
0.401619 | 2b3aad26ebb949eca762dd92fa220fbd | Mitochondrial Lon is required for ULK1-mediated mitophagy under hypoxia.A, B HCT-15 cells were transiently transfected with the plasmids encoding Lon or Lon-shRNA. Cell lysates were analyzed by immunoblotting using the indicated antibodies. GAPDH as the loading control. C HCT-15 cells transfected with the plasmids enco... | PMC10020552 | 41419_2023_5723_Fig2_HTML.jpg |
0.427118 | 0cc2bcfe6cd24455a12907da7bffffe5 | Mitochondrial Lon chaperone activity contributes to the stability of ULK1 complex for the mitophagy activation.A HCT-15 cells were transfected with the plasmids encoding pcDNA3-Lon in different concentrations (0.5–5 μg). Cell lysates were analyzed by immunoblotting using the indicated antibodies. GAPDH as the loading c... | PMC10020552 | 41419_2023_5723_Fig3_HTML.jpg |
0.48092 | c70c5a3680a2426e9fe3d0297a8aec53 | Lon and ULK1 complex accumulates at ER-mitochondria tethering sites in response to hypoxia.A, B Lon and ULK1 complex accumulates at ER-mitochondria contact (EMC) sites under hypoxia. HCT-15 cells treated with or without CoCl2 (200 μM for 18 h) (A) or transfected with the plasmids encoding myc-Lon (B) were used to perfo... | PMC10020552 | 41419_2023_5723_Fig4_HTML.jpg |
0.388374 | ca377606baee4fb093b158346e644901 | Mitochondrial Lon interacts with and stabilizes ULK1 complex under hypoxia.A–D Mitochondrial Lon interacts with ULK1 shown by co-immunoprecipitation. A HCT-15 cells were treated with CoCl2 followed by co-immunoprecipitation with anti-ULK1. Whole cell lysates from HCT-15 cells treated with CoCl2 (200 μM for 18 h) were i... | PMC10020552 | 41419_2023_5723_Fig5_HTML.jpg |
0.456904 | 4d7afbdd9ca649409ac11bfc8a8787fe | FUNDC1-Ser17 phosphorylation by ULK1 kinase at the EMC/MAM is important for the Lon-induced mitophagy.A HCT-15 cells transfected with the plasmids encoding myc-Lon were used to perform subcellular fractionation experiment. Cell lysates were analyzed by immunoblotting using the indicated antibodies. GAPDH as the loading... | PMC10020552 | 41419_2023_5723_Fig6_HTML.jpg |
0.418894 | 06993fd1d17b4b5fa68b80273191ebd0 | Lon binds with mitochondrial Na+/Ca2+ exchanger to promote FUNDC1-ULK-mediated mitophagy in the EMC/MAM site.A, B Ca2+mito (mt-lar-GECO) and Ca2+cyto (Fura-2 AM) were measured by live-cell microscopy in OEC-M1 treated with CoCl2 (300 µM-18h) or transfected with Lon in presence or absence of CGP37157 (10 µM-4h). ATP (10... | PMC10020552 | 41419_2023_5723_Fig7_HTML.jpg |
0.400998 | dcb298deaeaf449f942286fc08665dab | Lon-ROS-ULK1-FUNDC1 axis induced mitophagy benefits cell survival and tumorigenesis in vitro and in vivo.A–C HCT-15 cells were treated with CoCl2 (200 μM for 18 h) or not in the presence or absence of SBI-0206965 (20 μM for 24 h). The MTS assay for cell viability (A), fluorescence-based cleaved Caspase 3 apoptosis assa... | PMC10020552 | 41419_2023_5723_Fig8_HTML.jpg |
0.485286 | ceb8ce3b72d24364bf80c52c62997a4b | Neuropathic pain developed in SCI mice. (A) The SCI mouse model was generated by punching a hole in left L5 segment of spinal cord under vertebra thoracic segment 13 (T13) using a 26G needle. Injury site is marked with a red circle. (B) Hematoxylin and Eosin (H&E) staining of spinal cord sections showed that the injury... | PMC10020601 | fnmol-16-1091096-g001.jpg |
0.47353 | 3c21bf0542f545a5b4bd43ec33a7d111 | Upregulation of Nav1.7 in DRG and SDH of SCI mice. (A) The expression level of Nav1.7 in DRG and SDH of naive, sham, and SCI mice was measured by Western blot. (B) Quantitative analysis of duplicate Western-blot membranes showed that compared to naive mice, the expression level of Nav1.7 increased significantly in DRG ... | PMC10020601 | fnmol-16-1091096-g002.jpg |
0.393048 | ac8f1b267995473b987acb7feddd8917 | Induced expression of NGF in DRG and SDH of mice after SCI. (A) The expression level of NGF in DRG and SDH of naive, sham, and SCI mice was measured by Western blot. (B) Quantitative analysis of duplicate Western-blot membranes showed that there was an increase trend in the expression level of NGF in DRG and SDH in SCI... | PMC10020601 | fnmol-16-1091096-g003.jpg |
0.427457 | 8ab4fcca503d427d82b338ed94dfe3da | Expression of voltage-gated sodium channels in spinal dorsal horn and DRG of SCI mice at 12 DPO. (A) Western blot showed that the expression level of Nav1.2 was not significantly upregulated in SDH of SCI mice when compared to that in naive mice. (B) Western blot demonstrated that there was no significant difference in... | PMC10020601 | fnmol-16-1091096-g004.jpg |
0.377294 | 40dfbee1ce0645a0920f4a0a77ceb79c | Blockers of Nav1.7-alleviated mechanical pain in SCI mice. (A) Nav1.7 blocker PF-05089771 significantly relieved mechanical pain of SCI mice at doses of both 2 mg/kg and 4 mg/kg (Vehicle 0.03 ± 0.08 g, 2 mg/kg 30 min 0.2 ± 0.13 g, 4 mg/kg 30 min 0.3 ± 0.16 g, 2 mg/kg 60 min 0.4 ± 0.19 g, and 4 mg/kg 60 min 0.4 ± 0.20) ... | PMC10020601 | fnmol-16-1091096-g005.jpg |
0.423305 | 6e084465cea6446081c5beecfa4b2e2d | Activation of Nav1.7+ SDH neurons in SCI mice. (A–L) Double immunostaining for FOS (Red) and Nav1.7 (Green) on spinal section derived from naive (A, D, G, J), sham (B, E, H, K), and SCI (C, F, I, L) mice showed more FOS-positive neurons and more FOS/Nav1.7 double-positive neurons in deep laminae layers of SCI mice. Ins... | PMC10020601 | fnmol-16-1091096-g006.jpg |
0.409583 | b8ef477efe524218aa7c1c39f5168b82 | Increase of phosphorylated JUN in SDH and DRG of SCI mice. (A). The expression level of phosphorylated JUN in DRG and SDH of naive, sham, and SCI mice was measured by Western blot. (B) Quantitative analysis of the expression of phosphorylated JUN in DRG and SDH in naive, sham, and SCI (sham DRG 1.0 ± 0.26, SCI DRG 1.1 ... | PMC10020601 | fnmol-16-1091096-g007.jpg |
0.436764 | 5e215178dbc2412eb7e4126b29cfc1e8 | Schematic view of mechanism underlying SCI-induced NP. (A). SCI induced the upregulation of NGF, and consequently increased phosphorylated JUN and the upregulation of Nav1.7 in SDH and DRG neurons of mice. (B). Nav1.7 selective blockers attenuated SCI-induced NP in mice through inhibiting the activity of Nav1.7 in both... | PMC10020601 | fnmol-16-1091096-g008.jpg |
0.42195 | 88966ea211b24defa8104d8dd58b94e0 | Timeline of major retinal imaging instruments and landmark artificial intelligence applications in glaucoma. Introduction of landmark imaging instruments are listed in blue and AI events are provided in black.
AI, artificial intelligence; OCT, optical coherence tomography; OCTA, OCT angiography. | PMC10020779 | jovr-18-97-g001.jpg |
0.398453 | f66dd2cfc769400fbd70b3669e38c4ff | Evolution of AI in glaucoma. First row: Image processing and expert systems were used to identify glaucoma landmarks or features (such as cup-to-disc ratio or hemorrhages) from retinal images with the assistance of a glaucoma specialist and glaucoma landmarks are identified. Second row: Numerical parameters like raw vi... | PMC10020779 | jovr-18-97-g002.jpg |
0.396182 | 4e2afd5d54c54aa88a2c6d796c07f892 | Visual field (VF) and optical coherence tomography (OCT) image quantification. Top: VFs were quantified to 18 prominent patterns of VF loss based on classical archetypal analysis. Bottom: OCT circle scans were quantified to 16 patterns of RNFL loss based on deep archetypal analysis. | PMC10020779 | jovr-18-97-g003.jpg |
0.466144 | 65226d75ec19428eaf9391585b88bac9 | Geographical distribution of melioidosis cases from 2013–2018 Udupi District, Karnataka, India (n = 50).Base map republished from [20] under a CC BY license, with permission from Karnataka State Remote Sending Application Centre (KSRC), original copyright KSRC, 2022. | PMC10021467 | pgph.0000865.g001.jpg |
0.415497 | f6806cd9b1854cdb9fefc08e38432721 | Monthly distribution of average melioidosis cases and rainfall from 2013–2018, Udupi district, Karnataka, India (n = 50). | PMC10021467 | pgph.0000865.g002.jpg |
0.48338 | 71bcc270c7aa4e7a96d805c485814f65 | PRISMA flow diagram, article selection process. | PMC10021551 | pgph.0001085.g001.jpg |
0.447797 | 168cb2fc8e674d9ba3f4765be2bf603d | Proportion of individuals in different level of nutritional status based on the BMI indices. | PMC10021695 | pgph.0001176.g001.jpg |
0.403474 | 12d5205c7b3248dbac94a56bf7ed0537 | List of NCDs studied and their magnitude among participants attending chronic outpatient NCDs care, Bahir Dar, Ethiopia (N = 1432). | PMC10021695 | pgph.0001176.g002.jpg |
0.491603 | 98d698ec3e9243f7ba7f7a8543c386dc | Patterns of NCDs morbidity among individuals attending chronic NCDs care in Bahir Dar, Ethiopia (N = 1432). | PMC10021695 | pgph.0001176.g003.jpg |
0.447834 | 77dc2d64ea2e46ae80d9051216d02824 | Number of individuals classified in different categories of health-related QoL. | PMC10021695 | pgph.0001176.g004.jpg |
0.446598 | 2926cb5bc91146a0ab1f59f8c3a2018f | Graphic presentation of the relationship between QoL, functioning and multimorbidity. | PMC10021695 | pgph.0001176.g005.jpg |
0.403476 | 5b98719ca8b544cea39afafe75bcf830 | Localisation and diversity of natural water sites used by local population.(A) Localisation of all the unprotected and natural water sites visited in the study area. Datas for the administrative boundary were provided by Ministry of Territory Planning of Benin (https://gadm.org/download_country_v3.html). The map of riv... | PMC10021984 | pgph.0000095.g001.jpg |
0.412962 | d705765061a244d684ea3431e159ec8a | Identification of human activities at natural water sites.(A) Location of the 11 prospected water sites. Datas for the administrative boundary were provided by Ministry of Territory Planning of Benin (https://gadm.org/download_country_v3.html). The map of rivers was provided by Ministry of Mines, Energy and Hydraulics ... | PMC10021984 | pgph.0000095.g002.jpg |
0.454098 | b85f2ceb679748faa22a9e64675c361d | Factors involved in Buruli ulcer disease.(A) Location of Buruli ulcer patients participating in the prospective case-control study. Datas for the administrative boundary were provided by Ministry of Territory Planning of Benin (https://gadm.org/download_country_v3.html). (B) Age and sex distribution of Buruli ulcer pat... | PMC10021984 | pgph.0000095.g003.jpg |
0.414301 | e117cbbcaf8242218e35378ef023c739 | Detection of M. ulcerans at water sites.(A) Location of water sites from which environmental samples were collected. In green, water sites at which none of the pooled samples was positive for M. ulcerans DNA, and, in red, water sites at which at least one pooled sample tested positive for M. ulcerans DNA. Datas for the... | PMC10021984 | pgph.0000095.g004.jpg |
0.376562 | 90b852fe41eb46d994c862c8db6c9273 | Link between the area under water and endemicity.(A) PCA analysis with monthly data for water coverage by district and endemicity. (B) Example of surface water area for two districts: Gangban and Dame-Wogon. (C) Projection of axis 1 of the PCA. (D) projection of axis 2 of the PCA. (E) Incidence of Buruli ulcer in the d... | PMC10021984 | pgph.0000095.g005.jpg |
0.487803 | 7f993852e92648babd0c997da3fd9e39 | Census data (2013) & past vaccination tallies from Child Health Day 6-months earlier vs estimated denominators. | PMC10022106 | pgph.0000178.g001.jpg |
0.401202 | db86fdc21f2948129c0c599d55993d91 | Frequentist estimates of polio vaccination rates by commune. | PMC10022106 | pgph.0000178.g002.jpg |
0.379872 | 5c281d2bcede4b5c817a053c3f85c0fc | Bayesian estimates of polio vaccination rates by commune. | PMC10022106 | pgph.0000178.g003.jpg |
0.399121 | 63fd1591b9574895abf3b7046a6889c9 | Sensitivity analysis of polio vaccination rates by commune. | PMC10022106 | pgph.0000178.g004.jpg |
0.42032 | f50675301f5e4f71a7d4bbd829e7573c | Priming NK cells with IL-12, IL-15, and IL-18 prompts trained memory-like phenotypic alterations among different NK subpopulations. A Schema of isolating NK cells from peripheral blood mononuclear cells and priming them with IL-12, IL-15, and IL-18 or low concentrations of IL-15 for 16 h, washing and then resting in a ... | PMC10022190 | 12967_2023_4024_Fig1_HTML.jpg |
0.457669 | 8f508beec9e143ff8db9c2036216966a | Preactivation with IL-12, IL-15, and IL-18 induces CD25 and CD137 up-regulation on CIML NK. A Schema of in vitro experiments. Purified NK cells were activated with IL-12, IL-15, and IL-18 or control-treated for 16 h and washed. After differentiating for 6 days, NK cell phenotype and functionality were assessed. B Repre... | PMC10022190 | 12967_2023_4024_Fig2_HTML.jpg |
0.59117 | 65709fded4df495bbecfeb0bd280a27f | CIML NK cells exhibit enhanced functional responses against hepatocarcinoma targets. Representative bivariate mass cytometry plots of IFN-γ (A) and TNF-α (C) expressed by c-NK cells and CIML NK cells stimulated by HepG2 cells at the designated effector-to-target ratios (E: T). Summary of data (mean ± s.e.m.) from the s... | PMC10022190 | 12967_2023_4024_Fig3_HTML.jpg |
0.403743 | 819a0277cebb45688918cd4dbaba7ff8 | CIML NK-iRGD showed improved tumor infiltration capacity and antitumor efficiency in 3D tumor spheroids. A The constructed MCSs of iRGD-receptors-positive gastric cancer cell line HGC27. The image was obtained under 4 × magnification. The scale bar was 100 μm. B Representative morphological assessment of HGC27-MCSs was... | PMC10022190 | 12967_2023_4024_Fig4_HTML.jpg |
0.449427 | 628ad03b45cd4109a04a32fe824d1fb0 | iRGD-modified P-CIML NK cells effectively controlled tumor growth. A Experimental scheme of the antitumor experiment in vivo. Five-week-old female Babl/c-nude mice were subcutaneously injected with 5 × 106 HepG2 cells to initiate an antitumor experiment in vivo. After two weeks, 2 × 107 P-CIML NK (PBMCs were primed wit... | PMC10022190 | 12967_2023_4024_Fig5_HTML.jpg |
0.438624 | 815b842851b14a548a37ffd414403a62 | Design of this study | PMC10022191 | 12916_2023_2814_Fig1_HTML.jpg |
0.496504 | f1d0a47cdda842a0889d7e77c910cfda | Mean values of the plasma concentrations of Canocapavir over time in each treatment cohort (mean ± standard deviation) | PMC10022191 | 12916_2023_2814_Fig2_HTML.jpg |
0.46803 | 27816da112394009978f56ad2fc30a2a | Changes of HBV virologic markers from baseline during treatment with Canocapavir or placebo. A–C Hepatitis B virus (HBV) DNA, D–F HBV pregenomic RNA (pgRNA), G hepatitis B surface antigen (HBsAg), H hepatitis e surface antigen (HBeAg), I hepatitis B core-related antigen (HBcrAg) | PMC10022191 | 12916_2023_2814_Fig3_HTML.jpg |
0.494244 | b1200a89024d40908ea28a60b5b9fe30 | Conceptualization model: The decision process for each risk management method chosen. | PMC10022342 | pgph.0000159.g001.jpg |
0.43042 | 062620b78b99469b898e2ca08319cf09 | Contraceptive indicators between 1998 and 2016 (SADHS, 2016). | PMC10022780 | pone.0282996.g001.jpg |
0.436183 | af24987077054df39a2bfdde18eea7a5 | Pretreatment. A, Preoperative images for a 60-year-old man with cystic lymphatic malformation in the right thigh area. Four small yellow triangles indicate the area where the cyst existed. The white line shows the plane of MRI view. B, MRI on T2-weighted images showed a well-described extraarticular multi lobular cysti... | PMC10022848 | gox-11-e4871-g001.jpg |
0.43793 | b73cd5b5b5934ca4a8ef389ee7469a88 | Posttreatment. A, Lymphedema was improved with decreasing volume of lower limbs. The white line shows the plane of MRI view. B, MRI on T2-weighted images showing that the cystic lymphatic malformation resolved with no recurrence during 2 years of follow-up. | PMC10022848 | gox-11-e4871-g002.jpg |
0.42018 | 094eb2bfee0440eb82fbb8a020284d21 | Effect of high- vs. low-dose IV iron on fatal and non-fatal MI (time-to-first event analysis). (A) Fatal and non-fatal MI; (B) type 1 MI; (C) type 2 MI; (D) NSTEMI; and (E) STEMI. | PMC10022850 | cvab317f1.jpg |
0.420088 | e99fd15b81b340c8a80aeed3da5862fb | Effect of high- vs. low-dose IV iron on fatal and non-fatal MI (recurrent event analysis, i.e. first and subsequent events). | PMC10022850 | cvab317f2.jpg |
0.500402 | b447048894c4405aa6551a9f8cc0e01f | Comparison of the three platforms. (a) Schematic diagram of TIIA. (b) Schematic diagram of LFIA. (c) Schematic diagram of HCM. NC stands for negative control. | PMC10023210 | gr1_lrg.jpg |
0.456045 | 56862eb556e347159df55c74139baac9 | (a) The centrifugal tray was modified by the commercial pulling-force spinning top. (b–c) Experimental results of before (b) and after centrifugation (c). The concentration of N protein was 100 ng/mL. (d) The centrifugal speeds over time were performed by ten independent individuals. (e) Statistical analysis of velocit... | PMC10023210 | gr2_lrg.jpg |
0.549124 | fd1c0123356d4656a5a6e6e816ede3d9 | Optimization of condition in the homogeneous immunoreaction and centrifugal process. (a) The result of immunoreaction under different red latex nanobeads concentration (a), incubation time (b), centrifugation time (c), and centrifugation speed (d). | PMC10023210 | gr3_lrg.jpg |
0.422931 | cf1bcab90d3e4988815bbba9295b9ad7 | The sensitivity testing of two systems. (a) The photographic images of the LFIA after loading different concentrations of N protein of SARS-CoV-2. (b) The statistical result of (a), n = 3. (c) The photographic images of the HCM after loading different concentrations of N protein of SARS-CoV-2. (d) The statistical resul... | PMC10023210 | gr4_lrg.jpg |
0.445181 | d7749bfb66a64a6dac57cb22d09c82a1 | (a–b) The photographic images and corresponding statistical results (b) of the HCM after loading different samples (n = 3). (c) The results of the HCM for clinical samples. CS1-CS4 indicates clinical negative samples and CS4-CS9 indicates positive clinical samples. Each sample was tested three times. The inset represen... | PMC10023210 | gr5_lrg.jpg |
0.434478 | 286e3044bec444f2b49420e7dd5ec41a | Design and characterization of the orthogonal transcription system.a The binding of the orthogonal RNAP to its cognate promoters (with binding affinity KA) is a limiting step for protein synthesis in all organisms. The capping enzyme fused to RNAP ensures nuclear export and translation efficiency of the synthetic trans... | PMC10023750 | 41467_2023_37244_Fig1_HTML.jpg |
0.435872 | 659c0b70e9324b14b2b8e3c9d4d622ff | Resource competition model in the two-reporter system.a The genetic circuit design for the RNAP-driven expression of two reporter genes. b Characterization of resource competition by two co-expressed reporters in HEK293T. Experimental data and model predictions are compared at varying activities for the two reporters. ... | PMC10023750 | 41467_2023_37244_Fig2_HTML.jpg |
0.411238 | ddaaa26c7ef0488b82a30a5df48cf027 | Gene-order effect for three-gene expression and predictions of the resource-competition model.a Schematic of the three-reporter characterization system with all possible orders of the transcriptional units. b Relative activity of blue, yellow and red fluorescent proteins of each reporter gene (bfp, yfp, and mCherry) ba... | PMC10023750 | 41467_2023_37244_Fig3_HTML.jpg |
0.447394 | f446ec74f9654e8abcc27fbe975bb917 | Stoichiometry optimization of the three components for the influenza A subtype H1N1 VLP via the predictive model.a Schematic of the recombinant VLP in which NA and M1 proteins are fused with mCherry and GFP reporter proteins, respectively. b Transmission electron microscopy images of influenza VLPs. Scale bar, 50 nm. c... | PMC10023750 | 41467_2023_37244_Fig4_HTML.jpg |
0.433093 | 9636e337bff046d78d87238f0a8b0b23 | Identifying stromal Tumor Infiltrating Lymphocyte (TIL) regions in a H&E-stained WSI of breast cancer. (A) H&E-stained WSI of breast cancer. (B) Example of a region of tissue. (C) Example of stromal TILs (green solid arrow) and cells that are no TILs (red dotted arrow). The image shows how it can be challenging to visu... | PMC10025040 | gr1.jpg |
0.392489 | 7a7b0207cb5b4351873f9995f2c9f800 | Workflow of the approach developed in the study. Starting from H&E images from HER2+ and TN breast cancer, the approach starts with the segmentation of nuclei within tumor-associated associated stroma (A). Pathomic features were then extracted from cell segmentation within tumor-associated stroma (B). After the feature... | PMC10025040 | gr2.jpg |
0.436119 | d584981191fa46c999a7b00b82372b22 | Selected pathomic features (n = 21) after the three steps of feature selection. Surviving features were reported in bold. Abbreviations: FSD = Fourier Shape Descriptor; MAD = Median Absolute Deviation; IDM = Inverse Difference Moment; IMC = Information Measure of Correlation. | PMC10025040 | gr3.jpg |
0.434295 | 8bcf40998f4945d7a19499585173a09e | Receiver Operating Characteristic (ROC) curves of prediction models without resampling (A), with SMOTE-resampling (B) and with downsampling (C). Abbreviations: LDA = Linear Discriminant Analysis; KNN = K-Nearest Neighbour; DT = Decision Tree; RF = Random Forest; MLP = Multi-layer Perceptron. | PMC10025040 | gr4.jpg |
0.422289 | 64fe8c39364544aba9524223a4dd39f8 | Comparison of AUCROCs between different classification models and different resampling techniques. Abbreviations: SMOTE = synthetic minority oversampling technique; LDA = Linear Discriminant Analysis; KNN = K-Nearest Neighbour; DT = Decision Tree; RF = Random Forest; MLP = Multi-layer Perceptron. | PMC10025040 | gr5.jpg |
0.473148 | dbaf6079899e40c29f8595d24759f8cc | a Antoine Lacassagne Cancer Centre. Niza. b Medanta applicator AEOLO. c Pamplona applicator d Benidorm template | PMC10025210 | 12094_2022_3016_Fig1_HTML.jpg |
0.467345 | 7ae9fdf0d4a34057b59bb99544604017 | 3D printed applicator. Courtesy of Dr. Elena Villafranca | PMC10025210 | 12094_2022_3016_Fig2_HTML.jpg |
0.469828 | e5dc49d2a46b4c56b801a7440acf32e5 | Use of scout view to determine the needle tip on CT images | PMC10025210 | 12094_2022_3016_Fig3_HTML.jpg |
0.403631 | eef7523359b843b0803e17473ed015a8 | MRI images showing a “ballooning” artifact at the end of the titanium needle | PMC10025210 | 12094_2022_3016_Fig4_HTML.jpg |
0.413731 | 00b2576ecb584e02ae3bc9af1dfe6675 | Reconstruction method for titanium needles based on MRI images with the aid of MRI markers (A-vitamin pellets) | PMC10025210 | 12094_2022_3016_Fig5_HTML.jpg |
0.435222 | 746dc1801f834e2ebc82bc26ce67d572 | Example showing differences between geometrical and point-based optimisation | PMC10025210 | 12094_2022_3016_Fig6_HTML.jpg |
0.404698 | 64fe714789374bc2a627a18ce33fb3db | Schematic representation of the investigated training set designs for the prediction of location 1. | PMC10025381 | fpls-14-1080087-g001.jpg |
0.392328 | eb1e8ad40357416086737239af3b30c3 | Correlation between observed and predicted yield (A) and moisture (B) for training set designs CV3(within environment with no previous data) and CV6(within year with no previous data) in years 2013 to 2015 at locations 1 to 7. The median of 100 simulations for the prediction method RR-BLUP is shown on top of the respec... | PMC10025381 | fpls-14-1080087-g002.jpg |
0.427883 | 3dc971342a6b476b897974c1e7693314 | Correlation between observed and predicted yield (A) and moisture (B) for training set designs CV3(within environment with no previous data) and CV6(within year with no previous data) for one year, and training set designs CV1to CV8across one or two years. The median of 100 simulations for the prediction method RR-BLUP... | PMC10025381 | fpls-14-1080087-g003.jpg |
0.392892 | 8a1267b830ba4a45b1ee4057d0923e26 | Growth characteristics of longan fruits and their quantitative statistical scheme. | PMC10025382 | fpls-14-1132909-g001.jpg |
0.455975 | d60db449d0ee401c832eec3cf0d0e166 | Solution for longan fruit tree yield statistics. | PMC10025382 | fpls-14-1132909-g002.jpg |
0.448433 | 9ba2cf6e871b47caa6cdf3d7656c3bf1 | Schematic diagram of the image acquisition mode. | PMC10025382 | fpls-14-1132909-g003.jpg |
0.47082 | 3c3a72ef660d446cadba14145ef88c82 | Examples of the UAV images. | PMC10025382 | fpls-14-1132909-g004.jpg |
0.42433 | e6b5498732b641b38c6a4ac8ae0491cb | Diagram of the whole process. | PMC10025382 | fpls-14-1132909-g005.jpg |
0.39702 | 45a659949590453aa86f1e76a40adb84 | Flow chart of Cluster_Fruits and Single_Fruits quantity prediction. (A) The flow chart of Single_Fruit quantity statistics in a Cluster_Fruit, (B) The flow chart of Cluster_Fruit quantity statistics in a single fruit tree. | PMC10025382 | fpls-14-1132909-g006.jpg |
0.426232 | 7e8d881de5b443c6a21f4226fd87e593 | Clustering results of the target bounding boxes in the two datasets. | PMC10025382 | fpls-14-1132909-g007.jpg |
0.473441 | c1bd7a09ae274ea2b1aa6683b764c6ed | P-R curves and F1 scores of different detection methods. | PMC10025382 | fpls-14-1132909-g008.jpg |
0.408988 | 4b07a9950e2445438cc2daf61ff215c3 | Cluster_Fruit detection results of the CF-YD model under different scenes. | PMC10025382 | fpls-14-1132909-g009.jpg |
0.401388 | b09785b5be6e4cc58078f322562077fc | Single_Fruit detection results of the SF-YD model under different scenes. | PMC10025382 | fpls-14-1132909-g010.jpg |
0.422041 | f3da38734e984d7cb416a92f51d76076 | Cluster_Fruit counting results of the CF-YD model under different scenes. | PMC10025382 | fpls-14-1132909-g011.jpg |
0.39791 | 3b33e82d0d8a4f59859b0b0e704f7eb7 | Single_Fruit counting results of the SF-YD model under different scenes. | PMC10025382 | fpls-14-1132909-g012.jpg |
0.417344 | 5f0dbdb93b1048188b5dd4db0247f59d | The fitting results of the actual and identified numbers of fruits. | PMC10025382 | fpls-14-1132909-g013.jpg |
0.403866 | 70aa84e3036d40f989886331879654a4 | Statistical information of Cluster_Fruits and Single_Fruits. (A) The actual numbers, identified numbers and predicted numbers of Cluster_Fruits on six longan trees, (B) The actual numbers, identified numbers and predicted numbers of Single_Fruits on six Cluster_Fruits, (C) Error rate information of Cluster_Fruit on six... | PMC10025382 | fpls-14-1132909-g014.jpg |
0.418819 | c0d04d3100ee4a0c9fef4b57f7afd8c9 | Liposarcoma (a) Gross photograph showing a greyish yellow tumor in a mastectomy specimen (marked with arrow), (b)Histopathology shows a tumour composed of mature adipocytes of variable size along with highly pleomorphic cells with vesicular nuclei, prominent nucleoli and scant cytoplasm. There are lip blasts with few b... | PMC10025814 | JMH-13-257-g001.jpg |
0.508221 | 16fff269f581486d810091101a6534a0 | Tumor cells are positive for (a) Vimentin, and (b) focally for S-100 (×400) | PMC10025814 | JMH-13-257-g002.jpg |
0.40329 | c11bfa809d2c4a4c9b22d6778a78dcd6 | Magnetic resonance imaging (MRI) showing lobulated mass lesion in the sellar-suprasellar region, Inset - MRI contrast enhancement of the mass lesion | PMC10025822 | JMH-13-254-g001.jpg |
0.496954 | a472caed123442e5b49522b688e71fa1 | Squash cytology showing inflammatory infiltrate with few entangled epithelial cells (H and E, ×10) | PMC10025822 | JMH-13-254-g002.jpg |
0.442959 | d98eb4fc8a3b4acea23d0b9dd2f46975 | Pituitary glandular epithelium with infiltration by lymphocytes, few plasma cells, and macrophages (H and E, ×10) Inset - Higher power of the same (H and E, ×40) | PMC10025822 | JMH-13-254-g003.jpg |
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