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[A community-based prospective control study of comprehensive intervention in hypertensive patients]. | OBJECTIVE: To explore the effect of comprehensive intervention and the prognosis of hypertensive patients in a community.METHODS: To monitor and follow up the hypertencive patients in a community and their families, to intervene comprehensively and prospectively and to make comparison with a control group.RESULTS: The ... | ['Community Health Services', 'Comprehensive Health Care', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Prospective Studies', 'Treatment Outcome'] | 11,940,316 | [['N02.421.143'], ['N04.590.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adenosine restores myocardial responsiveness to insulin during acute endotoxin shock in vivo. | We recently reported that adenosine potentiated insulin-stimulated myocardial glucose uptake (MGU) in vivo and that adenosine receptor blockade resulted in myocardial insulin resistance. Since myocardial insulin resistance has been reported to occur during endotoxin shock, we decided to investigate whether infusion of ... | ['Adenosine', 'Animals', 'Dogs', 'Dose-Response Relationship, Drug', 'Female', 'Glucose', 'Glucose Clamp Technique', 'Hemodynamics', 'Hyperinsulinism', 'Insulin', 'Male', 'Myocardium', 'Oxygen Consumption', 'Shock, Septic', 'Time Factors'] | 2,673,569 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.875', 'G07.690.936.500'], ['D09.947.875.359.448'], ['E01.370.225.124.100.350', 'E05.196.500', 'E05.200.124.100.350'], ['G09.330.380'], ['C18.452.394.968'], ['D06.472.699.587.200.50... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The membrane-bound H(+)-ATPase complex is essential for growth of Lactococcus lactis. | The eight genes which encode the (F(1)F(o)) H(+)-ATPase in Lactococcus lactis subsp. cremoris MG1363 were cloned and sequenced. The genes were organized in an operon with the gene order atpEBFHAGDC; i.e., the order of atpE and atpB is reversed with respect to the more typical bacterial organization. The deduced amino a... | ['Base Sequence', 'Cell Membrane', 'DNA, Bacterial', 'Genes, Bacterial', 'Lactococcus lactis', 'Molecular Sequence Data', 'Operon', 'Proton-Translocating ATPases', 'Transcription, Genetic'] | 10,940,012 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.149'], ['D13.444.308.212'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['B03.353.750.737.500.400', 'B03.510.400.800.500.400', 'B03.510.550.737.500.400'], ['L01.453.245.667'], ['G05.360.340.024.686', 'G05.36... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Determining staffing requirements for a second shift of anesthetists by graphical analysis of data from operating room information systems. | Some operating room (OR) managers face the dilemma whereby all cases in a surgical suite are not completed during a regularly scheduled (e.g., 8-hour) day. If the anesthesia group at the surgical suite plans for its employed anesthetists to work a fixed number of hours each day, then more than 1 shift of anesthetists m... | ['Computer Graphics', 'Cost Control', 'Data Interpretation, Statistical', 'Decision Support Techniques', 'Humans', 'Needs Assessment', 'Nurse Anesthetists', 'Operating Room Information Systems', 'Operating Rooms', 'Personnel Staffing and Scheduling Information Systems', 'Seasons', 'Time Factors', 'Workforce', 'Workload... | 10,876,449 | [['L01.224.108', 'L01.296.110'], ['N03.219.151.160'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E05.245', 'L01.313.500.750.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['M01.526.485.140.650', '... | ['Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Profiling in wildlife crime: Recovery of human DNA deposited outside. | Incidents of bird of prey persecution receive a lot of media coverage in the UK, with investigations rarely recovering sufficient evidence to proceed to prosecution. One of the main challenges is to identify a suspect, as these offences are carried out in remote locations without witnesses, and crime scenes may not be ... | ['Animals', 'Conservation of Natural Resources', 'Crime', 'DNA', 'DNA Fingerprinting', 'Environment', 'Forensic Genetics', 'Humans', 'Touch'] | 29,673,693 | [['B01.050'], ['J01.256', 'N06.230.080'], ['I01.198.240', 'I01.880.735.191'], ['D13.444.308'], ['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['G16.500.275', 'N06.230'], ['H02.403.330.149', 'I01.198.780.937.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.816.... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Psychiat... | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
Expression in a wine yeast strain of the Aspergillus niger abfB gene. | A recombinant wine yeast strain has been constructed expressing the gene coding for alpha-L-arabinofuranosidase B from Aspergillus niger under the control of the yeast actin gene promoter. The protein is efficiently secreted by the recombinant yeast, allowing its purification and characterisation. The heterologous alph... | ['Aspergillus niger', 'Cloning, Molecular', 'Fermentation', 'Gene Expression Regulation, Fungal', 'Genes, Fungal', 'Glycoside Hydrolases', 'Recombinant Proteins', 'Saccharomyces cerevisiae', 'Wine'] | 8,961,556 | [['B01.300.381.081.450'], ['E05.393.220'], ['G02.111.158.249', 'G03.191.249'], ['G05.308.330'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['D08.811.277.450'], ['D12.776.828'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['G07.203.100.100.900', 'G07.203.200.887', 'J02... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Combination of two urinary biomarkers predicts acute kidney injury after adult cardiac surgery. | BACKGROUND: Urinary L-type fatty acid-binding protein (L-FABP) has not been evaluated for adult post-cardiac surgery acute kidney injury (AKI) to date. This study was undertaken to evaluate a biomarker panel consisting of urinary L-FABP and N-acetyl-â-D-glucosaminidase (NAG), a more established urinary marker of kidney... | ['Acetylglucosaminidase', 'Acute Kidney Injury', 'Aged', 'Area Under Curve', 'Biomarkers', 'Cardiac Surgical Procedures', 'Coronary Artery Bypass', 'Creatinine', 'Fatty Acid-Binding Proteins', 'Female', 'Heart Valves', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Predictive Value of Tests', 'Prospec... | 22,269,724 | [['D08.811.277.450.483.180.500'], ['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116.100'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D23.101'], ['E04.100.376', 'E04.928.220'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['D03.383.129.308.2... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Racial differences in co-occurring substance use and serious psychological distress: the roles of marriage and religiosity. | The study examined how marriage and religiosity can protect members of certain racial/ethnic groups against co-occurring substance use and serious psychological distress. Using the national dataset 2007 National Survey on Drug Use and Health, we analyzed data via multinomial logistic regression, observing several impor... | ['Adult', 'Comorbidity', 'Continental Population Groups', 'Female', 'Health Surveys', 'Humans', 'Male', 'Marriage', 'Social Class', 'Spirituality', 'Stress, Psychological', 'Substance-Related Disorders', 'United States'] | 22,506,867 | [['M01.060.116'], ['N05.715.350.225', 'N06.850.490.687'], ['M01.686.508'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.423.500.500', 'N01.224.361.500.500', 'N01.824.308... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Exercise may decrease further destruction in the adult haemophilic joint. | The effect of exercise on adult haemophilic joints was investigated. Forty-six subjects with existing joint disease were evaluated and range of motion (ROM) in joints was measured. The effect of exercise of large joint ROM in haemophilia was evaluated by comparing the ranges of motion in subjects who exercised at least... | ['Adult', 'Ankle Joint', 'Elbow Joint', 'Exercise Therapy', 'Hemarthrosis', 'Hemophilia A', 'Hip Joint', 'Humans', 'Knee Joint', 'Range of Motion, Articular', 'Shoulder Joint', 'Treatment Outcome'] | 16,643,207 | [['M01.060.116'], ['A02.835.583.378.062'], ['A02.835.583.290'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['C05.550.459', 'C23.550.414.794'], ['C15.378.100.100.500', 'C15.378.100.141.500', 'C15.378.463.500', 'C16.320.099.500'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The impact of disruptive innovations in orthopaedics. | The US healthcare system is currently facing daunting demographic and economic challenges. Because musculoskeletal disorders and disease represent a substantial and growing portion of this healthcare burden, novel approaches will be needed to continue to provide high-quality, affordable, and accessible orthopaedic care... | ['Ambulatory Care', 'Cooperative Behavior', 'Delivery of Health Care', 'Diffusion of Innovation', 'Health Care Costs', 'Health Services Accessibility', 'Humans', 'Marketing of Health Services', 'Musculoskeletal Diseases', 'Orthopedic Procedures', 'Outcome and Process Assessment, Health Care', 'Patient Care Team', 'Phys... | 19,415,405 | [['E02.760.106', 'N02.421.585.106'], ['F01.145.813.115'], ['N04.590.374', 'N05.300'], ['L01.143.320'], ['N03.219.151.400', 'N05.300.375'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.219.687.550', 'N03.219.463.548', 'N05.300.430.500'], ['C05'], ['E02.718', 'E04.555'], ['N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
[Imaging of the abdominal wall: combination of tissue-harmonic-imaging and extended field-of-view sonography]. | PURPOSE: To evaluate the combined use of extended field-of-view sonography and tissue harmonic imaging (THI) for assessment of the abdominal wall.MATERIALS AND METHODS: In 32 patients (25 patients without and 7 patients with abdominal wall pathologies) extended field-of-view sonography of the abdominal wall was perform... | ['Abdominal Wall', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Data Interpretation, Statistical', 'Female', 'Humans', 'Male', 'Middle Aged', 'Software', 'Tomography, X-Ray Computed', 'Ultrasonography'] | 15,573,297 | [['A01.923.047.050'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['L01.224.900'], ['E01... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Prevalence, incidence, risk factors and treatment of atrial fibrillation in Australia: The Australian Diabetes, Obesity and Lifestyle (AusDiab) longitudinal, population cohort study. | OBJECTIVE: We sought to describe the prevalence, incidence, risk factors and treatment (according to stroke risk) of atrial fibrillation (AF) in the national, population-based Australian Diabetes, Obesity and Lifestyle (AusDiab) study cohort.METHODS: ECG data were available from 8273/11,247 participants of AusDiab stud... | ['Aged', 'Atrial Fibrillation', 'Australia', 'Cohort Studies', 'Diabetes Mellitus', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Life Style', 'Longitudinal Studies', 'Male', 'Obesity', 'Population Surveillance', 'Prevalence', 'Risk Factors', 'Treatment Outcome'] | 26,730,844 | [['M01.060.116.100'], ['C14.280.067.198', 'C23.550.073.198'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C18.452.394.750', 'C19.246'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Resting energy expenditure in controls and cancer patients with localized and diffuse disease. | Resting energy expenditure (REE), nutritional parameters, and substrate levels were measured using a technique to minimize artifacts in 11 control patients, nine patients with localized, and four patients with diffuse neoplastic disease. Patients with diffuse disease had significantly increased percentage preillness we... | ['Adult', 'Aged', 'Blood Glucose', 'Body Weight', 'Creatinine', 'Energy Metabolism', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Rest', 'Serum Albumin', 'Skinfold Thickness', 'Transferrin'] | 6,703,790 | [['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D03.383.129.308.207'], ['G03.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04'], ['I03.450.769.647'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Constitutive variants of the pC194 cat gene exhibit DNA alterations in the vicinity of the ribosome binding site sequence. | The chloramphenicol-inducible regulation of the expression of cat genes from two Gram-positive bacteria, Staphylococcus aureus and Bacillus pumilus has been suggested to result from the presence of inverted repeat sequences that span the ribosome-binding site (RBS) for cat. In support of this hypothesis, we demonstrate... | ['Acetyltransferases', 'Bacillus', 'Base Sequence', 'Binding Sites', 'Chloramphenicol', 'Chloramphenicol O-Acetyltransferase', 'Chromosome Mapping', 'DNA, Bacterial', 'Gene Expression Regulation', 'Genes, Bacterial', 'Plasmids', 'Protein Biosynthesis', 'Ribosomes', 'Staphylococcus aureus'] | 6,588,016 | [['D08.811.913.050.134'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['D08.811.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Expression of the acetyl low density lipoprotein receptor by rabbit fibroblasts and smooth muscle cells. Up-regulation by phorbol esters. | The acetyl low density lipoprotein (LDL), or scavenger, receptor, which binds modified forms of LDL, was thought to be expressed only on macrophages and endothelial cells. We demonstrate that rabbit fibroblasts and smooth muscle cells bind, internalize, and degrade acetoacetylated LDL, a ligand for the acetyl LDL recep... | ['Animals', 'Cell Adhesion Molecules', 'Culture Media', 'Endocytosis', 'Fibroblasts', 'In Vitro Techniques', 'Lipoproteins, LDL', 'Muscle, Smooth', 'Phorbol Esters', 'Polysaccharides', 'Protein Kinase C', 'Rabbits', 'Receptors, LDL', 'Receptors, Scavenger', 'Up-Regulation'] | 2,373,709 | [['B01.050'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['D27.720.470.305', 'E07.206'], ['G04.417'], ['A11.329.228'], ['E05.481'], ['D10.532.515', 'D12.776.521.550'], ['A02.633.570', 'A10.690.467'], ['D02.455.849.291.500.510'], ['D09.698'], ['D08.811.913.696.620.682.700.725'], ['B01.050.150.900... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Double-blind study comparing erythromycin and mupirocin for treatment of impetigo in children: implications of a high prevalence of erythromycin-resistant Staphylococcus aureus strains. | Staphylococcus aureus has been consistently isolated from a high proportion of impetiginous lesions, and in several recent studies, it was present in the majority of the cases. Since recently a large proportion of S. aureus strains in our community showed erythromycin resistance, we undertook a prospective double-blind... | ['Bacteria', 'Child', 'Child, Preschool', 'Double-Blind Method', 'Drug Resistance, Microbial', 'Erythromycin', 'Female', 'Humans', 'Impetigo', 'Infant', 'Israel', 'Male', 'Microbial Sensitivity Tests', 'Mupirocin', 'Patient Compliance', 'Penicillin Resistance', 'Staphylococcus aureus'] | 1,605,593 | [['B03'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['G06.225', 'G07.690.773.984.269'], ['D02.540.576.500.992'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.868.951.360', 'C01.150.252.410.890.587', 'C01.150.252.819.... | ['Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Carbamazepine monotherapy in the treatment of alcohol withdrawal. | More than 135 different strategies for medical treatment have been described for the treatment of alcohol withdrawal syndromes. The substances used most frequently (benzodiazepines, barbiturates, or clomethiazol) themselves pose some risk for abuse or addiction. Anticonvulsants, especially carbamazepine (CBZ), have bee... | ['Adult', 'Carbamazepine', 'Electroencephalography', 'Ethanol', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Substance Withdrawal Syndrome'] | 2,081,898 | [['M01.060.116'], ['D03.633.300.240.127'], ['E01.370.376.300', 'E01.370.405.245'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.513.653'], ['C25.775.835', 'F03.900.825']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of social conditions during adolescence on courtship and aggressive behavior are not abolished by adult social experience. | Social experience during adolescence has long-lasting consequences for adult social behavior in many species. In zebra finches, individuals reared in pairs during adolescence start to court females faster, sing more courtship motifs to females and are more aggressive compared with group-reared males. We investigated wh... | ['Age Factors', 'Aggression', 'Animals', 'Courtship', 'Female', 'Finches', 'Male', 'Social Behavior', 'Vocalization, Animal'] | 25,545,997 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.145.126.125', 'F01.145.813.045'], ['B01.050'], ['F01.145.802.279'], ['B01.050.150.900.248.620.750.250'], ['F01.145.813'], ['F01.145.113.055.800']] | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Global model analysis by parameter space partitioning. | To model behavior, scientists need to know how models behave. This means learning what other behaviors a model can produce besides the one generated by participants in an experiment. This is a difficult problem because of the complexity of psychological models (e.g., their many parameters) and because the behavioral pr... | ['Humans', 'Models, Psychological', 'Space Perception'] | 16,478,301 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['F02.463.593.778']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of KinesioTape on the treatment of lateral epicondylitis. | STUDY DESIGN: Randomized clinical trial.INTRODUCTION: KinesioTape (KT) is a noninvasive method to treat pain and muscular dysfunction.PURPOSE: To investigate the effect of KT with and without tension on pain intensity, pain pressure threshold, grip strength and disability in individuals with lateral epicondylitis, and ... | ['Adult', 'Athletic Tape', 'Female', 'Hand Strength', 'Humans', 'Middle Aged', 'Myofascial Pain Syndromes', 'Pain Measurement', 'Tennis Elbow', 'Treatment Outcome'] | 28,256,305 | [['M01.060.116'], ['E07.101.036', 'E07.858.442.743.159'], ['E01.370.600.425.500', 'G11.427.560.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.651.550'], ['E01.370.600.550.324'], ['C05.651.869.435.500', 'C26.088.890', 'C26.874.800.500.500'], ['E01.789.800', 'N04.761.559.590.800', 'N05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The clonal nature of pityriasis lichenoides. | BACKGROUND: Pityriasis lichenoides et varioliformis acuta (PLEVA) and pityriasis lichenoides chronica (PLC) are benign lymphocytic infiltrates of the skin that classically present as either a recurrent papulonecrotic eruption (PLEVA) or a persistent, scaling, papular eruption (PLC). Observations of both types of lesion... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Clonal Anergy', 'Female', 'Gene Order', 'Genes, T-Cell Receptor', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Pityriasis Lichenoides', 'Prospective Studies', 'Retrospective Studies'] | 12,164,744 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['G12.535.425.100'], ['G05.340'], ['G05.360.340.024.340.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['C17.800.859.475.650', 'C17.800.859.575.650', 'C17.800.859.600.650'], ['E05... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Progress in the diagnosis of unknown primary neoplasms]. | About 5% of tumours clinically begin as unknown origin metastases involving some difficult diagnostic and therapeutic problems. In these cases the main goal is the formulation of the diagnosis as rapidly as possible because only about 10-15% of diagnosed patients are susceptible of treatment. Between 1973-1989 we obser... | ['Adenocarcinoma', 'Adult', 'Aged', 'Bone Neoplasms', 'Carcinoma', 'Carcinoma, Squamous Cell', 'Female', 'Histocytochemistry', 'Humans', 'Immunohistochemistry', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasms, Unknown Primary'] | 2,097,558 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C04.588.149', 'C05.116.231'], ['C04.557.470.200'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['B01.05... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Semantic information is used by a deep dyslexic to parse compounds. | We report a case study of a 48 year-old patient, J.O., who was tested 20 years after the removal of a tumor in the left temporal-parietal region. This surgery and subsequent radiation resulted in right side paralysis and numerous language problems. Tests of J.O.'s single word reading abilities indicate that she could b... | ['Aphasia', 'Dyslexia, Acquired', 'Female', 'Functional Laterality', 'Humans', 'Middle Aged', 'Parietal Lobe', 'Semantics', 'Severity of Illness Index', 'Temporal Lobe', 'Vocabulary'] | 11,527,330 | [['C10.597.606.150.500.800.100', 'C23.888.592.604.150.500.800.100'], ['C10.597.606.150.500.300.200', 'C10.597.606.150.550.200.500', 'C23.888.592.604.150.500.300.200', 'C23.888.592.604.150.550.200.500', 'F03.615.700', 'F03.625.562.400.500'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.4... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
COSTS OF DEPRESSION FROM CLAIMS DATA FOR MEDICARE RECIPIENTS IN A POPULATION-BASED SAMPLE. | BACKGROUND: Many persons with depressive disorder are not treated and associated costs are not recorded.AIMS OF THE STUDY: To determine whether major depressive disorder (MDD) is associated with higher medical cost among Medicare recipients.METHODS: Four waves of the Baltimore-Epidemiologic Catchment Area (Baltimore EC... | ['Aged', 'Baltimore', 'Catchment Area, Health', 'Depressive Disorder, Major', 'Female', 'Health Care Costs', 'Humans', 'Insurance Claim Review', 'Male', 'Medicare', 'United States'] | 27,483,975 | [['M01.060.116.100'], ['Z01.107.567.875.500.500.100', 'Z01.433.100'], ['N01.224.791.200', 'N03.349.650.095', 'N06.850.505.400.800.200'], ['F03.600.300.375'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.215'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.343... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Design of a HIV-1-derived HLA-B07.02-restricted polyepitope construct. | OBJECTIVE: To design a vaccine construct containing various but conserved HIV-1-derived epitopes and generating broad CD8 T cell responses.METHODS: HLA-B7 transgenic H-2KD KO transgenic mice were used to identify potential new HLA-B07.02-restricted HIV-1-derived epitopes. Immunological recognition of these epitopes was... | ['AIDS Vaccines', 'Animals', 'Antigens, Viral', 'Cytotoxicity, Immunologic', 'Epitopes, T-Lymphocyte', 'HIV-1', 'HLA-B Antigens', 'HLA-B7 Antigen', 'Mice', 'Mice, Knockout', 'Mice, Transgenic', 'Oligopeptides', 'T-Lymphocytes, Cytotoxic', 'Vaccines, DNA'] | 19,644,347 | [['D20.215.894.899.050'], ['B01.050'], ['D23.050.327'], ['G12.287'], ['D23.050.550.402'], ['B04.820.650.589.650.350.400'], ['D12.776.395.550.489.500', 'D12.776.543.550.439.500', 'D23.050.301.500.100.500', 'D23.050.301.500.450.380', 'D23.050.705.552.100.500', 'D23.050.705.552.450.380'], ['D12.776.395.550.489.500.070', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Left single lung transplantation in treatment of idiopathic pulmonary fibrosis: a case report]. | A single left lung transplantation was performed on a 48-year-old male with end-stage idiopathic pulmonary fibrosis in February 1995. The surgical technic used was similar to that mentioned in the literature. The donor lung was perfused by cold Euro-Collins solution with a cold ischemic time of 190 minutes. Cardiopulmo... | ['Graft Rejection', 'Humans', 'Immunosuppressive Agents', 'Lung Transplantation', 'Male', 'Methylprednisolone', 'Middle Aged', 'Pulmonary Fibrosis'] | 9,275,683 | [['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['E04.928.600.495', 'E04.936.450.495'], ['D04.210.500.745.432.769.795.539'], ['M01.060.116.630'], ['C08.381.765']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Autologous transfusion. A safe alternative for the 1990s. | Autologous transfusion is a safe and affordable alternative to the traditional use of homologous blood. Many persons who would not ordinarily meet the criteria for homologous or directed donation can be autologous donors. The use of autologous blood ensures that the patient will not contract AIDS or hepatitis from tran... | ['Blood Banks', 'Blood Donors', 'Blood Transfusion, Autologous', 'Clinical Protocols', 'Health Services Needs and Demand', 'Humans'] | 1,518,758 | [['N02.278.065.200'], ['M01.898.313'], ['E02.095.135.164'], ['E02.183', 'N05.715.360.330.125'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Phasic variations of extracellular potassium during fictive swimming in the lamprey spinal cord in vitro. | The lamprey spinal cord in vitro can generate the motor pattern underlying locomotion, which can be recorded with suction electrodes in the ventral roots. To test if the extracellular level of potassium changed during rhythmic activity, potassium-sensitive microelectrodes were used to systematically (every 25 micromete... | ['Animals', 'Brain Stem', 'Extracellular Space', 'Fishes', 'Ganglia, Spinal', 'Lampreys', 'Locomotion', 'Microelectrodes', 'Potassium', 'Spinal Cord', 'Swimming'] | 6,741,576 | [['B01.050'], ['A08.186.211.132'], ['A10.082.500', 'A11.284.295'], ['B01.050.150.900.493'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['B01.050.150.900.493.559'], ['G07.568.500', 'G11.427.410.568'], ['E07.305.250.500'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Calcitonin gene-related peptide improves skin flap survival and tissue inflammation. | The effects of systemic administration of calcitonin gene-related peptide (CGRP) on survival and inflammation of experimental skin flaps subjected to prolonged arterial ischemia were studied. An island groin flap was elevated in the rat. The femoral artery was occluded for 8, 10, 12 or 14 h in four groups of 10 rats. I... | ['Animals', 'Calcitonin Gene-Related Peptide', 'Constriction', 'Femoral Artery', 'Graft Survival', 'Inflammation', 'Male', 'Peroxidase', 'Rats', 'Rats, Sprague-Dawley', 'Skin', 'Surgical Flaps', 'Time Factors'] | 10,189,062 | [['B01.050'], ['D12.644.400.097', 'D12.776.631.650.097'], ['E05.225'], ['A07.015.114.351'], ['G12.875.545.340'], ['C23.550.470'], ['D08.811.682.732.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['A17.815'], ['A10.850.710', 'E07.862.710'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Grand Challenge: Unbiased Phenotypic Function of Metabolites from Jaspis splendens against Parkinson's Disease. | A grand challenge in natural product chemistry is to determine the biological effects of all natural products. A phenotypic approach is frequently used for determining the activity of a compound and its potential impact on a disease state. Chemical investigation of a specimen of Jaspis splendens collected from the Grea... | ['Animals', 'Depsipeptides', 'Drug Screening Assays, Antitumor', 'Humans', 'Indole Alkaloids', 'Molecular Structure', 'Parkinson Disease', 'Porifera'] | 26,883,470 | [['B01.050'], ['D04.345.566.297', 'D12.644.641.297'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.132.436', 'D03.633.100.473.402', 'D03.633.100.496.500.500'], ['G02.111.570', 'G02.466'], ['C10.228.140.079.862.500', 'C10.228.662.600... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preliminary observations on the results of combined 125iodine seed implantation and external irradiation for carcinoma of the prostate. | Fifty-seven patients with localized carcinoma of the prostate were treated with pelvic lymphadenectomy and a reduced 125iodine implant dosage, supplemented by a moderate dose of external beam radiotherapy to the whole pelvis delivered 4 to 6 weeks later. The incidence of pelvic nodal metastases was 28 per cent and the ... | ['Adenocarcinoma', 'Aged', 'Brachytherapy', 'Follow-Up Studies', 'Humans', 'Iodine Radioisotopes', 'Lymph Node Excision', 'Male', 'Middle Aged', 'Pelvis', 'Proctitis', 'Prostatic Neoplasms', 'Radioisotope Teletherapy', 'Radiotherapy', 'Time Factors'] | 7,069,833 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['E02.815.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['E04.446'], ['M01.060.116.630'], ['A01.923.600']... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lactate dehydrogenase of trout: hybridization in vivo and in vitro. | Speckled trout and lake trout contain five forms of lactate dehydrogenase, but a diflerent electrophoretic distribution of isozymes characterizes each species. The hybrid splake, which is produced artificially by fertilizing lake trout eggs with speckled trout sperm, contains nine isozymes. This comnplement of isozymeg... | ['Animals', 'Electrophoresis', 'Enzymes', 'Eye', 'Fishes', 'Gels', 'Hybridization, Genetic', 'In Vitro Techniques', 'Isoenzymes', 'L-Lactate Dehydrogenase', 'Species Specificity'] | 5,909,780 | [['B01.050'], ['E05.196.401', 'E05.301.300'], ['D08.811'], ['A01.456.505.420', 'A09.371'], ['B01.050.150.900.493'], ['D20.280.320', 'D26.255.165.320'], ['E05.820.150.390', 'G05.090.390'], ['E05.481'], ['D08.811.348', 'D12.776.800.300'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['G16.824']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The MDR1 3435 polymorphism in patients with rheumatoid arthritis. | OBJECTIVE: Rheumatoid arthritis (RA) is a multifactorial disease, the pathogenesis of which involves immunological, genetic and environmental factors. P-glycoprotein (P-gp) encoded by the MDR1 gene, is an important transporter for many drugs, xenobiotics and cytokines and may be associated with many immunological proce... | ['Adult', 'Aged', 'Arthritis, Rheumatoid', 'Case-Control Studies', 'DNA', 'DNA Primers', 'Female', 'Genes, MDR', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Polymorphism, Restriction Fragment Length'] | 15,487,808 | [['M01.060.116'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D13.444.308'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.360.340.024.340.361', 'G05.360.340.024.340.645.50... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Biofeedback and gifted children: an initial investigation. | 37 intellectually gifted students were given a 15-min. training session in EMG frontalis biofeedback to determine its effectiveness for reduction of stress. While differences across sex in biofeedback training were not found, these highly able students significantly reduced their levels of tension. | ['Adolescent', 'Biofeedback, Psychology', 'Child', 'Child, Gifted', 'Electromyography', 'Female', 'Humans', 'Male', 'Relaxation Therapy', 'Stress, Psychological'] | 3,900,921 | [['M01.060.057'], ['E02.190.525.123', 'F02.830.131', 'F04.754.137.301', 'F04.754.308.500'], ['M01.060.406'], ['F02.784.629.228.350', 'M01.102.350'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.525.875', 'F04.754.137.750'], ['F01.145.126.990', 'F02.830.900']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Methodologies in assaying prostate cancer stem cells. | The cancer stem cell (CSC) theory posits that only a small population of tumor cells within the tumor has the ability to reinitiate tumor development and is responsible for tumor homeostasis and progression. Tumor initiation is a defining property of putative CSCs, which have been reported in both blood malignancies an... | ['Animals', 'Biological Assay', 'Biomarkers, Tumor', 'Cell Culture Techniques', 'Cell Separation', 'Humans', 'Male', 'Mice', 'Mice, SCID', 'Neoplasm Metastasis', 'Neoplasm Transplantation', 'Neoplastic Stem Cells', 'Prostatic Neoplasms'] | 19,582,423 | [['B01.050'], ['E05.091'], ['D23.101.140'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of Salmonella typhimurium mutants in a model of experimental gastroenteritis. | Salmonella typhimurium strains harboring independent, defined mutations in aroA, invA, ssrA, or msbB were assessed for their ability to induce fluid accumulation, tissue damage, and local inflammation in rabbit ileal loops. Three wild-type strains of S. typhimurium, TML, HWSH, and SL1344, and two mutant strains, S. typ... | ['3-Phosphoshikimate 1-Carboxyvinyltransferase', 'Alkyl and Aryl Transferases', 'Animals', 'Bacterial Proteins', 'Disease Models, Animal', 'Gastroenteritis', 'Ileum', 'Mutation', 'Rabbits', 'Salmonella Infections, Animal', 'Salmonella typhimurium'] | 10,338,486 | [['D08.811.913.225.735'], ['D08.811.913.225'], ['B01.050'], ['D12.776.097'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C06.405.205'], ['A03.556.124.684.249', 'A03.556.249.124'], ['G05.365.590'], ['B01.050.150.900.649.313.968.700'], ['C01.150.252.400.310.821.706', 'C22.812'], ['B03.440.450.425.800.200.825', 'B03.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Revision of the genus Setosella (Bryozoa: Cheilostomata) with description of new species from deep-waters and submarine caves of the Mediterranean Sea. | The genus Setosella included to date six species. After revision, only four of these species were retained, i.e. S. vulnerata, S. cavernicola, S. folini and S. spiralis. The remaining two species were tentatively placed in Woodipora, W.? antilleana n. comb., and Andreella, A.? fragilis n. comb. On the other hand, scan... | ['Animals', 'Bryozoa', 'Caves', 'Mediterranean Sea'] | 32,229,881 | [['B01.050'], ['B01.050.500.217'], ['G01.311.169', 'G16.500.275.067', 'N06.230.066'], ['Z01.756.592']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Comparison of three commercially available thrombomodulin ELISA kits. | Thrombomodulin is a transmembranous glycoprotein of endothelial cells. In vitro it is a marker of endothelial cell injury. In vivo the levels of soluble serum thrombomodulin are regarded as parameters of disease activity in vasculitides and vasculopathies. However, the mean thrombomodulin values of different studies sh... | ['Adolescent', 'Adult', 'Aged', 'Blotting, Western', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'Reagent Kits, Diagnostic', 'Thrombomodulin'] | 15,087,235 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Structure of the joint region and the termini of the DNA of herpes simplex virus type 1. | Analysis of restriction endonuclease cleavage sites within the inverted, repeated sequences in the joint region of the DNA of herpes simplex virus type 1 strain KOS revealed the presence of two types of sequence heterogeneity. The first was an insertion of 280 base pairs or multiples of 280 base pairs which was found i... | ['Base Sequence', 'DNA Restriction Enzymes', 'DNA, Viral', 'Models, Chemical', 'Nucleic Acid Conformation', 'Simplexvirus'] | 211,266 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.568'], ['E05.599.495'], ['G02.111.570.820.486', 'G05.360.580'], ['B04.280.382.100.750']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Interobserver agreement for the bedside clinical assessment of suspected stroke. | BACKGROUND AND PURPOSE: Stroke remains primarily a clinical diagnosis, with information obtained from history and examination determining further management. We aimed to measure inter-rater reliability for the clinical assessment of stroke, with emphasis on items of history, timing of symptom onset, and diagnosis of st... | ['Aged', 'Aged, 80 and over', 'Cerebrovascular Disorders', 'Humans', 'Models, Statistical', 'Neurology', 'Observer Variation', 'Reproducibility of Results', 'Risk Factors', 'Stroke', 'Time Factors', 'Treatment Outcome'] | 16,484,609 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300', 'C14.907.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['H02.403.600'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E05.3... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Chlorinated benzo-1,2-quinones: an example of chemical transformation of toxicants during tests with aquatic organisms. | An analytical procedure specific for chlorinated benzo-1,2-quinones has been developed to examine the stability of these compounds under conditions used for investigating their toxicity to aquatic organisms. Solutions of the compounds in a number of organic solvents were unstable in the light, and addition of acetone s... | ['Acetylation', 'Animals', 'Benzoquinones', 'Chlorine', 'Chromatography, Gas', 'Environmental Monitoring', 'Fishes', 'Gas Chromatography-Mass Spectrometry', 'Half-Life', 'Kinetics', 'Oxidation-Reduction', 'Photochemistry', 'Water Pollutants, Chemical'] | 1,844,397 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['D02.806.250'], ['D01.268.380.150', 'D01.362.225'], ['E05.196.181.349'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.493'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G01.910.405'], ['G01.374.661', 'G02.111.490'], ['G02.700', 'G0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Prospective, randomized, multicenter trial on the antiproliferative effect of lanreotide, interferon alfa, and their combination for therapy of metastatic neuroendocrine gastroenteropancreatic tumors--the International Lanreotide and Interferon Alfa Study Group. | PURPOSE: Somatostatin analogs and interferon alfa control hormone-active/functional neuroendocrine gastroenteropancreatic tumors. In addition to hormonal control, variable degrees of antiproliferative effects for both agents have been reported. Until now, however, no prospective, randomized studies in therapy-naive pat... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Female', 'Gastrointestinal Neoplasms', 'Humans', 'Injections, Subcutaneous', 'Interferon alpha-2', 'Interferon-alpha', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Metast... | 12,860,945 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.620'], ['D12.644.276.374.440.890.250.500', 'D12... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Augmentation of urea-synthetic capacity by inhibition of nitric oxide synthesis in butyrate-induced differentiated human hepatocytes. | We have recently developed an in vitro differentiation model of immortalized non-transformed human hepatocytes using butyrate, and observed the induction of inducible NO synthase (iNOS). In this study, we analyzed the effect of NO on the urea-synthetic capacity of these cells. The inhibition of iNOS during butyrate tre... | ['Argininosuccinate Synthase', 'Basic Helix-Loop-Helix Leucine Zipper Transcription Factors', 'Butyric Acid', 'CCAAT-Enhancer-Binding Proteins', 'Cell Differentiation', 'Cell Line', 'DNA-Binding Proteins', 'Enzyme Induction', 'Epidermal Growth Factor', 'Genistein', 'Hepatocyte Nuclear Factor 4', 'Humans', 'Liver', 'NF-... | 10,838,080 | [['D08.811.464.259.300'], ['D12.776.260.103.500', 'D12.776.260.108.092', 'D12.776.930.125.500', 'D12.776.930.127.092'], ['D02.241.081.114.750', 'D10.251.400.143.500'], ['D12.776.260.108.124', 'D12.776.660.167', 'D12.776.930.127.124'], ['G04.152'], ['A11.251.210'], ['D12.776.260'], ['G05.308.320.200'], ['D06.472.317.350... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metabolomics analysis reveals distinct profiles of nonmuscle-invasive and muscle-invasive bladder cancer. | Urothelial carcinoma is the most common form of bladder cancer, but pathway changes that occur with stage-wise progression have not been well defined. We used a metabolomics approach to identify potential metabolic pathways uniquely altered in normal urothelium, nonmuscle-invasive bladder cancer (NMIBC), and muscle-inv... | ['Aged', 'Carcinoma, Transitional Cell', 'Cell Line, Tumor', 'Chromatography, Liquid', 'Citric Acid Cycle', 'Disease Progression', 'Female', 'Gas Chromatography-Mass Spectrometry', 'Glycolysis', 'Humans', 'Male', 'Metabolomics', 'Middle Aged', 'Neoplasm Grading', 'Purines', 'Pyrimidines', 'Urinary Bladder Neoplasms'] | 28,766,915 | [['M01.060.116.100'], ['C04.557.470.200.430'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.196.181.400'], ['G02.111.165', 'G03.295.342', 'G03.493.170'], ['C23.550.291.656'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Screening blood products for HTLV-I: what is the best approach? | A recent concern for disease transmission by blood transfusion is T-lymphotropic virus type I (HTLV-I). This virus is endemic in Japan, the Caribbean basin, subsaharan Africa, and, to a lesser extent, the southeastern United States and parts of Central and South America. HTLV-I, which has been shown to be transmitted... | ['Blood', 'Blood Donors', 'Blood Transfusion', 'Cost-Benefit Analysis', 'Decision Trees', 'HTLV-I Infections', 'Human T-lymphotropic virus 1', 'Humans'] | 10,149,525 | [['A12.207.152', 'A15.145'], ['M01.898.313'], ['E02.095.135'], ['N03.219.151.125'], ['G17.162.500'], ['C01.925.782.815.200.470', 'C20.673.483.470'], ['B04.613.807.200.725.400', 'B04.820.650.200.725.400'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reduced graft-versus-host reaction of T cells in Kaposi's sarcoma: a possible prognostic indicator. | In 20 patients with Kaposi's sarcoma (KS) the level of B and T lymphocytes in the peripheral blood, as well as the function of T cells measured by the graft-versus-host reaction (GVHR), were investigated. Analysis of the results regarding the distribution of skin lesions showed that the mean GVHR was within normal rang... | ['Adult', 'Aged', 'Animals', 'B-Lymphocytes', 'Female', 'Graft vs Host Reaction', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Rats', 'Rats, Inbred Lew', 'Sarcoma, Kaposi', 'Skin Neoplasms', 'T-Lymphocytes'] | 6,332,750 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G12.875.402'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['B01.050.150.900.649.313.992.635.505.700'], ['... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Vertebroplasty: reusable flange converter with hub lock for injection of polymethylmethacrylate with screw-plunger syringe. | During percutaneous vertebroplasty, a screw-plunger syringe provides a powerful controlled injection, but coupling of the screw plunger with interchangeable disposable standard syringe barrels results in syringe flange bending failure during the middle of the injection. A flange converter produced from stainless steel ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bone Cements', 'Cementation', 'Female', 'Humans', 'Injections', 'Male', 'Middle Aged', 'Polymethyl Methacrylate', 'Radiography, Interventional', 'Spinal Fractures', 'Syringes'] | 11,867,812 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['E05.170', 'E06.095.170'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530'], ['M01.060.116.630'], ['D02.241.081.069.800.550.500', 'D05.75... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Comparative study on metal homeostasis and detoxification in two Antarctic teleosts. | The main characteristic of Antarctic seawater is its low constant temperature and its high concentration of O(2), which can increase the formation rate of reactive oxygen species (ROS), together with a natural occurrence of elevated cadmium and copper levels. In the present paper, we studied the presence of cadmium, co... | ['Animals', 'Cold Temperature', 'Ecosystem', 'Female', 'Glutathione', 'Homeostasis', 'Liver', 'Metallothionein', 'Metals, Heavy', 'Oxidoreductases', 'Perciformes', 'Species Specificity', 'Tissue Distribution', 'Water Pollutants, Chemical'] | 22,309,987 | [['B01.050'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G16.500.275.157', 'N06.230.124'], ['D12.644.456.448'], ['G07.410'], ['A03.620'], ['D12.776.556.670'], ['D01.268.556', 'D01.552.544'], ['D08.811.682'], ['B01.050.150.90... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Voluntariness and coercion in patients with schizophrenia]. | OBJECTIVE: Associations between voluntariness of treatment, success of treatment, and number of hospital admissions should be examined.PATIENTS: 88 consecutive admissions with ICD-10 F2 disorders were assessed using the PANSS and the GAF at admission and discharge. Voluntariness was assessed regarding admission, hospit... | ['Adolescent', 'Adult', 'Aged', 'Ambulatory Care', 'Coercion', 'Commitment of Mentally Ill', 'Female', 'Follow-Up Studies', 'Germany', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Outcome and Process Assessment, Health Care', 'Patient Acceptance of Health Care', 'Patient Readmission', 'Psychiatric Status Rating ... | 14,727,196 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.760.106', 'N02.421.585.106'], ['I01.880.604.316', 'I01.880.630.200'], ['F04.096.544.335.200', 'N03.706.535.351.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Measurement of sarcoplasmic reticulum Ca2+ ATPase activity using high-performance liquid chromatography. | The goal of this investigation was to develop an assay whereby we could measure changes in ATP, ADP, and phosphocreatine (PCr) during stimulation of the sarcoplasmic reticulum (SR) Ca2+ ATPase. After stopping the enzyme reaction, compounds were extracted by perchloric acid and separated by reversed-phase high-performan... | ['Adenosine Diphosphate', 'Adenosine Triphosphate', 'Animals', 'Calcium-Transporting ATPases', 'Chromatography, High Pressure Liquid', 'Kinetics', 'Muscle, Skeletal', 'Phosphocreatine', 'Rats', 'Sarcoplasmic Reticulum'] | 17,967,437 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813.250'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Weight gain in response to high-fat feeding in CD-1 male mice. | The purpose of this study was to compare weight gain and food intake during high-fat feeding in outbred CD-1 male mice while considering several different experimental designs. This study was completed using data from three separate experiments and was designed to address different experimental design issues. Experimen... | ['Age Factors', 'Animal Feed', 'Animals', 'Animals, Outbred Strains', 'Dietary Fats', 'Eating', 'Housing, Animal', 'Male', 'Mice', 'Physical Conditioning, Animal', 'Research Design', 'Weight Gain'] | 20,427,378 | [['N05.715.350.075', 'N06.850.490.250'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.050.284'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['G07.203.650.283', 'G10.261.330'], ['J03.340.250', 'N06.230.150.360.250'], ['B01.050.150.900.649.313.992.635.505.500'], ['G11.427.410.698.277.280'], ... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Decreased Expression of Cystathionine â-Synthase Exacerbates Intestinal Barrier Injury in Ulcerative Colitis. | BACKGROUND AND AIMS: Endogenous H2S regulates multiple physiological and pathological processes in colon epithelial tissues. The current study investigated the role of cystathionine â-synthase [CBS], a major producer of H2S in colon epithelial cells, in the pathogenesis of ulcerative colitis [UC]-related intestinal bar... | ['Adult', 'Caco-2 Cells', 'Cells, Cultured', 'Colitis, Ulcerative', 'Cystathionine beta-Synthase', 'DNA Methylation', 'Female', 'Humans', 'Interferons', 'Intestinal Mucosa', 'Male', 'Signal Transduction', 'Tight Junctions', 'Transcription Factor RelA', 'Transcriptome', 'Tumor Necrosis Factor-alpha'] | 30,722,010 | [['M01.060.116'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['A11.251'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['D08.811.520.241.300.200'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Human immunodeficiency virus infection in pregnant women, transmission and zidovudine therapy. | OBJECTIVE: To determine the rate of mother to child transmission of HIV infection in women treated with zidovudine (ZDV).PATIENTS AND METHODS: A consecutive series of 52 HIV-positive pregnant women who either received antenatal care or delivered at our institution. Forty-three women were known to be HIV positive before... | ['Adult', 'Birth Weight', 'CD4 Lymphocyte Count', 'Cesarean Section', 'Delivery, Obstetric', 'Female', 'Fetal Monitoring', 'Gestational Age', 'HIV Infections', 'Heart Rate, Fetal', 'Humans', 'Infant, Newborn', 'Infectious Disease Transmission, Vertical', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Sexual Partn... | 11,435,008 | [['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Increasing prevalence of infectious diseases in asylum seekers at a tertiary care hospital in Switzerland. | OBJECTIVE: The increasing number of refugees seeking asylum in Europe in recent years poses new challenges for the healthcare systems in the destination countries. The goal of the study was to describe the evolution of medical problems of asylum seekers at a tertiary care centre in Switzerland.METHODS: At the Universit... | ['Adult', 'Chickenpox', 'Female', 'Humans', 'Malaria', 'Male', 'Pneumonia', 'Prevalence', 'Refugees', 'Skin Diseases, Bacterial', 'Switzerland', 'Tertiary Care Centers', 'Tuberculosis'] | 28,617,860 | [['M01.060.116'], ['C01.925.256.466.930.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.530', 'C01.920.875'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['M01.755'], ['C01.150.252.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
CEOs as risk takers--from vision to reality. | Health care management today is inherently risky. And because of the environment of high CEO turnover and bottom-line responsibility in which executives work, some CEOs become enmeshed in a crisis-management mode on a day-to-day basis. But there are some administrators with broader visions of what their institutions sh... | ['Hospital Administrators', 'Humans', 'Organizational Innovation', 'Risk-Taking', 'United States'] | 2,227,888 | [['M01.526.070.490.490', 'M01.526.485.430.490', 'M01.526.485.740.380', 'N02.360.430.490', 'N02.360.740.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.610'], ['F01.145.722'], ['Z01.107.567.875']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mechanism of action of phorbol myristate acetate on human natural killer cell activity. | We have investigated the kinetics of inhibition and regeneration of human natural killer (NK) cell-mediated lysis of K562, a human erythroleukemia cell line, by the potent tumor-promoting agent phorbol-12-myristate-13-acetate (PMA). It is shown that PMA inhibits NK cell-mediated cytotoxicity (CMC) in a dose-dependent m... | ['Calcimycin', 'Cell Adhesion', 'Cell Line', 'Cytochalasins', 'Cytotoxicity, Immunologic', 'Humans', 'Killer Cells, Natural', 'Kinetics', 'Leukemia, Myeloid, Acute', 'Mycotoxins', 'Phorbols', 'Tetradecanoylphorbol Acetate'] | 6,411,354 | [['D03.633.100.221.173'], ['G04.022'], ['A11.251.210'], ['D03.633.100.473.231', 'D23.946.587.370'], ['G12.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['G01.374.661', 'G02.111.490'], ['C04.557.337.539.275'], ['D23.946.587'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protective immunization against Helicobacter stimulates long-term immunity. | Immunization with an oral vaccine composed of whole cell sonicates of Helicobacter felis plus cholera toxin (CT) can protect mice from H. felis challenge. The aim of this study was to determine whether this protective immunity was long-lived. Mice were given the vaccine then left for up to 15 months before challenge. A... | ['Animals', 'Bacterial Vaccines', 'Cholera Toxin', 'Female', 'Helicobacter Infections', 'Immunity, Mucosal', 'Immunoglobulin A', 'Immunoglobulin G', 'Mice', 'Mice, Inbred BALB C', 'Saliva', 'Time Factors'] | 8,817,825 | [['B01.050'], ['D20.215.894.135'], ['D08.811.913.400.725.115.180', 'D23.946.123.194', 'D23.946.330.150'], ['C01.150.252.400.466'], ['G12.450.573'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.114.619.026'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies on the supply of immunoglobulin G to newborn camel calves (Camelus dromedarius). | A major problem in camel productivity is the high mortality rate of camel calves in the first 3 months. The causes for mortality are mainly poor management practice and infectious diseases. The purpose of this research, carried out on a ranch in Kenya, was to determine the immunoglobulin G (IgG) concentration in camel ... | ['Animal Husbandry', 'Animals', 'Animals, Newborn', 'Camelus', 'Colostrum', 'Immunity, Maternally-Acquired', 'Immunoglobulin G', 'Reference Values', 'Time Factors'] | 11,289,259 | [['J01.040.090'], ['B01.050'], ['B01.050.050.282'], ['B01.050.150.900.649.313.500.190.180'], ['A12.200.194'], ['G12.450.570'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['E05.978.810'], ['G01.910.857']] | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Investigation of the potential mobility of Pb, Cd and Cr(VI) from moderately contaminated farmland soil to groundwater in Northeast, China. | The adsorption/desorption of Pb, Cd and Cr(VI) on moderately contaminated farmland soils in Northeast China and the effect of pH value on adsorption/desorption were investigated. Soil column leaching experiment was also carried out to further understand the mobility of the three metals in aeration zone of soil. Both La... | ['Cadmium', 'China', 'Chromium', 'Hydrogen-Ion Concentration', 'Kinetics', 'Lead', 'Soil Pollutants', 'Thermodynamics', 'Water Pollutants, Chemical'] | 18,650,011 | [['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['Z01.252.474.164'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D01.268.556.435', 'D01.552.544.435'], ['D27.888.284.756'], ['G01.906'], ['D27.888.284.903.655']] | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Simulation of surface EMG for the analysis of muscle activity during whole body vibratory stimulation. | This study aims to reproduce the effect of motor-unit synchronization on surface EMG recordings during vibratory stimulation to highlight vibration evoked muscle activity. The authors intended to evaluate, through numerical simulations, the changes in surface EMG spectrum in muscles undergoing whole body vibration stim... | ['Action Potentials', 'Electrodes', 'Electromyography', 'Humans', 'Muscles', 'Signal Processing, Computer-Assisted'] | 24,183,387 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['E07.305.250'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633', 'A10.690'], ['L01.224.800']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Foreign-body reactions to fracture fixation implants of biodegradable synthetic polymers. | Biodegradable rods of polyglycolide or lactide-glycolide copolymer were used in the internal fixation of a variety of fractures and osteotomies in 516 patients. A clinically manifest foreign-body reaction occurred in 41 patients (7.9%), producing a fluctuant swelling at the implantation site after an average of 12 week... | ['Adolescent', 'Adult', 'Aged', 'Biotransformation', 'Female', 'Foreign-Body Reaction', 'Fracture Fixation, Internal', 'Humans', 'Male', 'Middle Aged', 'Osteotomy', 'Polymers', 'Prostheses and Implants', 'Time Factors'] | 2,199,452 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['C23.550.470.251', 'C26.392.560'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.555.580'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['E07.695'], ['G01.910.857']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Challenge of large-scale motion for residual dipolar coupling based analysis of configuration: the case of fibrosterol sulfate A. | Fibrosterol sulfate A is a polysulfated bis-steroid with an atypical side chain. Due to the flexibility of the linker, large-scale motions that change dramatically the shape of the entire molecule are expected. Such motions pose major challenges to the structure elucidation and the correct determination of configuratio... | ['Magnetic Resonance Spectroscopy', 'Molecular Conformation', 'Molecular Dynamics Simulation', 'Motion', 'Sterols'] | 21,776,994 | [['E05.196.867.519'], ['G02.111.570.820'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G01.482'], ['D04.210.500.247.808', 'D10.570.938']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Expression of bcl-2 protein is associated with shorter survival in nonsmall cell lung carcinoma. | BACKGROUND: The aim of this study was to assess the relationship between the expression of the 27-kilodalton (kD) bcl-2 protein and survival among nonsmall cell lung carcinoma (NSCLC) patients.METHODS: Paired tissue samples of histologically confirmed tumor and uninvolved lung of 91 randomly selected NSCLC patients wer... | ['Aged', 'Blotting, Western', 'Carcinoma, Non-Small-Cell Lung', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Prognosis', 'Proportional Hazards Models', 'Proto-Oncogene Proteins c-bcl-2', 'Survival Analysis'] | 12,833,466 | [['M01.060.116.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunochromatographic assay on thread. | Lateral-flow immunochromatographic assays are low-cost, simple-to-use, rapid tests for point-of-care screening of infectious diseases, drugs of abuse, and pregnancy. However, lateral flow assays are generally not quantitative, give a yes/no answer, and lack multiplexing. Threads have recently been proposed as a support... | ['Antibodies', 'C-Reactive Protein', 'Chromatography, Affinity', 'Cotton Fiber', 'Leptin', 'Osteopontin', 'Point-of-Care Systems', 'Polyesters'] | 22,889,381 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.196.181.400.170'], ['J01.637.836.299'], ['D06.472.699.042.500', 'D12.644.276.024.500', 'D12.644.548.011.500', 'D12.776.467.024.500', 'D23.529.024.500'], ['D12.644.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The role of arginine, indomethacin and kallikrein in the treatment of oligoasthenospermia. | We have treated 45 patients with various degrees of oligospermia and asthenospermia with arginine, indomethacin and kallikrein. Fifteen patients have received the amino acid L-arginine hydrochloride, 15 the antiinflammatory agent indomethacin, while 15 others the enzyme kallikrein. These drugs have been administered fo... | ['Adult', 'Anti-Inflammatory Agents, Non-Steroidal', 'Arginine', 'Drug Therapy, Combination', 'Humans', 'Indomethacin', 'Kallikreins', 'Male', 'Oligospermia', 'Sperm Count', 'Sperm Motility', 'Treatment Outcome'] | 7,591,579 | [['M01.060.116'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.420'], ['D08.811.277.656.300.760.442', 'D08.811.277.656.959.350.442', 'D12.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparison of two benzodiazepine hypnotics administered with alcohol. | Two benzodiazepine hypnotics were administered alone or in combination with alcohol to normal male volunteers. In the doses given, alcohol potentiated the effects of the benzodiazepines on some but not all performance measures. | ['Anti-Anxiety Agents', 'Attention', 'Drug Synergism', 'Ethanol', 'Flurazepam', 'Humans', 'Male', 'Memory, Short-Term', 'Psychological Tests', 'Psychomotor Performance', 'Reaction Time', 'Triazolam'] | 6,126,474 | [['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['F02.830.104.214'], ['G07.690.773.968.477'], ['D02.033.375'], ['D03.633.100.079.080.070.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['F04.711'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Testis development in a mouse with 10% of XY cells. | Two mouse Y-chromosome-related DNA probes were used to show that an aspermic sterile male mouse with small testes contained only approximately 10% of normal XY cells dispersed among normal XX cells. Examination of testis sections by in situ hybridization revealed that XY cells were nonrandomly concentrated in the testi... | ['Animals', 'Chimera', 'DNA', 'Karyotyping', 'Male', 'Mice', 'Nucleic Acid Hybridization', 'Sex Chromosome Aberrations', 'Testis', 'X Chromosome', 'Y Chromosome'] | 3,596,011 | [['B01.050'], ['B05.200'], ['D13.444.308'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.393.661', 'G02.111.611'], ['C23.550.210.815', 'G05.365.590.175.815'], ['A05.360.444.849', 'A05.360.576.782', 'A06.300.312.782'], ['A11.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Loss of EGFR confers acquired resistance to AZD9291 in an EGFR-mutant non-small cell lung cancer cell line with an epithelial-mesenchymal transition phenotype. | PURPOSE: AZD9291 is an irreversible, small-molecule inhibitor which has potency against mutant EGFR- and T790M-resistant mutation. Despite the encouraging efficacy in clinical, the acquired resistance will finally occur. Further study will need to be done to identify the acquired resistance mechanisms and determine the... | ['Acrylamides', 'Aniline Compounds', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line, Tumor', 'Drug Resistance, Neoplasm', 'Epithelial-Mesenchymal Transition', 'ErbB Receptors', 'Exons', 'Gene Deletion', 'Humans', 'Lung Neoplasms', 'Mitogen-Activated Protein Kinases', 'Protein Kinase Inhibitors', 'Proto-Oncogene Proteins ... | 29,797,219 | [['D02.065.122', 'D02.241.081.069.094'], ['D02.092.146'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G07.690.773.984.395'], ['G04.356.500'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.0... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies on the bacterial spore coat. 6. Effects of alkali extraction on the spore of Bacillus thiaminolyticus. | Thin sections of the spore of Bacillus thiaminolyticus Matsukawa and Misawa show a characteristic surface structure with five ridges, and a series of three distinct layers. The outer layer of the spore coat was peeled off by SDS sonic treatment, and then the middle layer was solubilized by alkali extraction of the SDS ... | ['Bacillus', 'Cell Wall', 'Sodium Dodecyl Sulfate', 'Sodium Hydroxide', 'Sonication', 'Spores, Bacterial'] | 617,210 | [['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['A11.284.183'], ['D02.033.415.220.720', 'D02.886.645.600.055.050.632', 'D10.289.220.720'], ['D01.045.250.750', 'D01.248.497.158.459.475', 'D01.857.745'], ['E05.848'], ['A11.870.700', 'B05.7... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Catch composition, reproductive biology and diet of the bramble shark Echinorhinus brucus (Squaliformes: Echinorhinidae) from the south-eastern Arabian Sea. | Fishery and biological data are presented for the poorly known bramble shark Echinorhinus brucus (Squaliformes: Echinorhinidae), from the deep waters of the south-eastern Arabian Sea. A total of 5318 individuals from by-catch landings of deep-water bottom set longlines, gillnets and shrimp trawl fisheries operating at ... | ['Animals', 'Diet', 'Female', 'Fisheries', 'Food Chain', 'Gastrointestinal Contents', 'India', 'Male', 'Oceans and Seas', 'Sexual Maturation', 'Sharks'] | 24,580,658 | [['B01.050'], ['G07.203.650.240'], ['J01.040.168.300', 'J03.540.280'], ['G16.500.275.157.250', 'N06.230.124.250'], ['A12.519'], ['Z01.252.245.393'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['G07.345.750.750', 'G08.686.841.750'], ['B01.050.150.900.493.370.853']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Statistical process control for validating a classification tree model for predicting mortality--a novel approach towards temporal validation. | Prediction models are postulated as useful tools to support tasks such as clinical decision making and benchmarking. In particular, classification tree models have enjoyed much interest in the Biomedical Informatics literature. However, their prospective predictive performance over the course of time has not been inves... | ['Aged', 'Critical Care', 'Female', 'Humans', 'Male', 'Models, Statistical', 'Mortality', 'Prognosis'] | 21,907,826 | [['M01.060.116.100'], ['E02.760.190', 'N02.421.585.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.308.985.550'], ['E01.789']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ischemia/reperfusion-induced pancreatitis in rats: a new model of complete normothermic in situ ischemia of a pancreatic tail-segment. | Ischemia/reperfusion injury plays an important role in the development of graft pancreatitis and thrombosis after pancreas transplantation. Up to now there are few therapeutic options for this severe complication because very little is known about pancreatic ischemia/reperfusion injury. The same pathomechanisms may als... | ['Animals', 'Disease Models, Animal', 'Hemoglobins', 'Ischemia', 'Lipase', 'Male', 'Microcirculation', 'Oxygen', 'Pancreas', 'Pancreatitis', 'Rats', 'Rats, Wistar', 'Reperfusion', 'Reperfusion Injury'] | 11,467,402 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.776.124.400', 'D12.776.422.316.762'], ['C23.550.513'], ['D08.811.277.352.100.400'], ['G09.330.100.645'], ['D01.268.185.550', 'D01.362.670'], ['A03.734'], ['C06.689.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Family relationships and morale among people 65 years of age and older. | The interrelationship of specific types of family relationship--marital and parent-child relations in particular--among older adults is examined. Findings suggest that caution must be exercised when generalizing about the importance of family relationships in the lives of older adults, and that future inquiries should ... | ['Aged', 'Family', 'Female', 'Humans', 'Male', 'Marriage', 'Morale', 'Parent-Child Relations', 'Role', 'Social Adjustment'] | 434,123 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effectiveness of Enteral Versus Oral Nutrition With a Medium-Chain Triglyceride Formula to Prevent Malnutrition and Growth Impairment in Infants With Biliary Atresia. | OBJECTIVES: The aim of this study was to compare the effectiveness of oral (PO) versus enteral nutrition (EN) medium-chain triglyceride (MCT) containing-formula to prevent malnutrition and growth impairment in infants with biliary atresia (BA) waiting for a liver transplant.METHODS: A total of 15 infants, 3 to 9 months... | ['Anthropometry', 'Biliary Atresia', 'Body Weight', 'Dietary Supplements', 'Energy Intake', 'Enteral Nutrition', 'Female', 'Growth Disorders', 'Humans', 'Infant', 'Infant Formula', 'Infant Nutrition Disorders', 'Liver Transplantation', 'Male', 'Recommended Dietary Allowances', 'Triglycerides', 'Waiting Lists'] | 26,196,199 | [['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['C06.130.120.123', 'C06.198.125', 'C16.131.314.125'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G07.203.300.456', 'J02.500.456'], ['G07.203.650.240.340'], ['E02.421.360', 'E02.642.500.36... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Analysis of seating and fracturing torque of bicortical screws. | The purpose of this study was to analyze and compare the seating and fracturing torque of 2.0-mm- versus 2.7-mm-diameter titanium screws. Six cadaver mandibles were sectioned at the symphysis and 20 drill hole locations were chosen on each half. Half the holes were designated for the 2.0-mm screws, tapped and nontapped... | ['Bone Density', 'Bone Screws', 'Equipment Design', 'Equipment Failure', 'Humans', 'Mandible', 'Materials Testing', 'Rotation', 'Stress, Mechanical', 'Tensile Strength', 'Titanium'] | 8,169,711 | [['G11.427.100'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E05.320'], ['E05.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['E05.570'], ['G01.482.703'], ['G01.374.835'], ['G01.374.850'], ['D01.268.557.800', 'D01.268.956.878', '... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Long-term results after laparoscopic resection of colorectal carcinoma]. | BACKGROUND: Laparoscopic techniques are currently used for curative resection of colorectal cancer although long-term results from controlled clinical trials are not available yet that prove laparoscopic procedures are adequate.METHODS: All patients who under-went a curative resection of a colorectal tumor from 1995 to... | ['Cohort Studies', 'Colorectal Neoplasms', 'Disease-Free Survival', 'Female', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Prospective Studies', 'Treatment Outcome'] | 10,354,845 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tumor Cell Subtypes Based on the Intracellular Hormonal Activity in KCNJ5-Mutated Aldosterone-Producing Adenoma. | Aldosterone-producing adenomas (APAs) harbor marked intratumoral heterogeneity in terms of morphology, steroidogenesis, and genetics. However, an association of biological significance of morphologically identified tumor cell subtypes and genotypes is virtually unknown. KCNJ5 mutation is most frequently detected and ge... | ['Adrenal Cortex Neoplasms', 'Adrenocortical Adenoma', 'Adult', 'Aldosterone', 'Cytochrome P-450 CYP11B2', 'Female', 'G Protein-Coupled Inwardly-Rectifying Potassium Channels', 'Humans', 'Lipid Droplets', 'Male', 'Microscopy, Electron, Transmission', 'Middle Aged', 'Mitochondria', 'Mutation'] | 30,354,756 | [['C04.588.322.078.265', 'C19.053.098.265', 'C19.053.347.500', 'C19.344.078.265'], ['C04.588.322.078.265.500', 'C19.053.098.265.500', 'C19.053.347.500.500', 'C19.344.078.265.500'], ['M01.060.116'], ['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['D08.244.453.484.500', 'D08.244.453.915.050', 'D08.811.682.69... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulatory role of FGF-2 on type I collagen expression during endothelial mesenchymal transformation. | PURPOSE: To investigate the regulatory role of FGF-2 on type I collagen expression during endothelial mesenchymal transformation (EMT).METHODS: Corneal endothelial cells (CECs) treated with FGF-2 from the primary culture to the third passage were transformed and designated as fibroblastic CECs (fCECs). Steady state lev... | ['Animals', 'Cell Line, Transformed', 'Cell Proliferation', 'Chromones', 'Collagen Type I', 'Electrophoresis, Polyacrylamide Gel', 'Endothelium, Corneal', 'Enzyme Inhibitors', 'Fibroblast Growth Factor 2', 'Immunoblotting', 'Mesoderm', 'Microscopy, Confocal', 'Microscopy, Fluorescence', 'Morpholines', 'Phenotype', 'Pho... | 16,303,940 | [['B01.050'], ['A11.251.210.172'], ['G04.161.750', 'G07.345.249.410.750'], ['D03.383.663.283.266', 'D03.633.100.150.266'], ['D05.750.078.280.300.100', 'D12.776.860.300.250.300.100'], ['E05.196.401.402', 'E05.301.300.319'], ['A09.371.060.067.318', 'A09.371.060.217.318', 'A10.272.491.318'], ['D27.505.519.389'], ['D12.644... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improved understanding of the bacterial vaginal microbiota of women before and after probiotic instillation. | The vaginal bacterial microbiota of 19 premenopausal women was examined by PCR-denaturing gradient gel electrophoresis (DGGE) and sequencing of the V2-V3 region of the 16S rRNA gene. Ten of the women were studied further to investigate the effect and persistence of vaginally inserted capsules containing viable lactobac... | ['Adult', 'Bacteria', 'Culture Media', 'DNA, Bacterial', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Genes, rRNA', 'Humans', 'Lactobacillus', 'Middle Aged', 'Polymerase Chain Reaction', 'Premenopause', 'Probiotics', 'RNA, Ribosomal, 16S', 'Random Amplified Polymorphic DNA Technique', 'Sequence Analysis, DNA', 'Va... | 12,513,982 | [['M01.060.116'], ['B03'], ['D27.720.470.305', 'E07.206'], ['D13.444.308.212'], ['E05.196.401.402', 'E05.301.300.319'], ['G05.360.340.024.340.645.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['M01.060.116.630'], ['E05.393.620.500'... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Controlled colonic insufflation by a remotely triggered capsule for improved mucosal visualization. | BACKGROUND AND STUDY AIMS: Capsule endoscopy is an attractive alternative to colorectal cancer screening by conventional colonoscopy, but is currently limited by compromised mucosal visibility because of the lack of safe, controlled colonic insufflation. We have therefore developed a novel system of untethered, wireles... | ['Animals', 'Capsule Endoscopy', 'Carbon Dioxide', 'Colon', 'Colonoscopy', 'Feasibility Studies', 'Female', 'Insufflation', 'Intestinal Mucosa', 'Swine'] | 24,845,802 | [['B01.050'], ['E01.370.388.250.250.250.140'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.8... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Computerized tomography: an unreliable method for accurate staging of bladder tumors in patients who are candidates for radical cystectomy. | A total of 164 patients with bladder tumors underwent preoperative staging by computerized tomography. All patients were previously untreated, or had undergone only transurethral biopsy or resection of the tumor before computerized tomography. The post-cystectomy histological stage was compared to the preoperative comp... | ['Adult', 'Aged', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Tomography, X-Ray Computed', 'Urinary Bladder', 'Urinary Bladder Neoplasms'] | 2,795,754 | [['M01.060.116'], ['M01.060.116.100'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810'], ['A05.810.890'], ['C04.58... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Metastasis of a renal adenocarcinoma to the residual ureteral stump. | A case of metastasis of a renal adenocarcinoma in the residual ureteral stump following nephrectomy is reported. A ureteral tumour was diagnosed 4 years after the nephrectomy, presenting as persistent haematuria and diagnosed by retrograde ureterography. | ['Adenocarcinoma', 'Humans', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Nephrectomy', 'Radiography', 'Ureteral Neoplasms'] | 7,286,009 | [['C04.557.470.200.025'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['M01.060.116.630'], ['E04.950.774.435'], ['E01.370.350.700'], ['C04.588.945.947.940', 'C12.758.820.875', 'C12.777.725.676', 'C13.351.93... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reviewing trends in the incidence of cancrum oris in Ibadan, Nigeria. | The objective of this clinic based retrospective study was to review the trends in the incidence of cancrum oris at the Dental clinic of the University College Hospital, Ibadan, Nigeria. Records of children aged 1 to 16 years diagnosed as having cancrum oris between 1st of January 1986 to 31st December, 2000 were revie... | ['Child', 'Child, Preschool', 'Developing Countries', 'Female', 'Humans', 'Immunocompromised Host', 'Incidence', 'Infant', 'Male', 'Nigeria', 'Noma', 'Nutrition Disorders', 'Retrospective Studies'] | 12,769,302 | [['M01.060.406'], ['M01.060.406.448'], ['I01.615.500.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.470'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.703'], ['Z01.058.290.190.565'], ['C07.465.604'], ['C18.654'], ['E05.318.37... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Seasonality and monthly dynamics of marine myovirus communities. | Marine myoviruses (i.e. bacteriophages with a contractile tail sheath) are numerically abundant and genetically diverse. We developed a terminal restriction fragment length polymorphism assay (TRFLP) for g23, the conserved gene encoding the major capsid protein, to investigate T4-like myovirus communities at USC's Micr... | ['Aquatic Organisms', 'Bacteria', 'Capsid Proteins', 'Environment', 'Genetic Variation', 'Myoviridae', 'Polymorphism, Restriction Fragment Length', 'Population Density', 'RNA, Ribosomal, 16S', 'Seasons'] | 22,507,260 | [['B05.080', 'G16.500.275.725.500.650.075'], ['B03'], ['D12.776.964.970.600.550'], ['G16.500.275', 'N06.230'], ['G05.365'], ['B04.100.500', 'B04.123.150.500', 'B04.280.090.500'], ['G05.365.795.595'], ['N01.224.600', 'N06.850.505.400.600'], ['D13.444.735.686.670'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Parallel double helices of DNA. Conformational analysis of regular helices with the second order symmetry axis. | We have performed a conformational analysis of DNA double helices with parallel directed backbone strands connected with the second order symmetry axis being at the same time the helix axis. The calculations were made for homopolymers poly(dA).poly(dA), poly(dC).poly(dC), poly(dG) poly(dG), and poly(dT).poly(dT). All p... | ['Base Composition', 'DNA', 'Models, Chemical', 'Nucleic Acid Conformation'] | 2,310,521 | [['G02.111.080'], ['D13.444.308'], ['E05.599.495'], ['G02.111.570.820.486', 'G05.360.580']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fatal neurocryptococcosis in a Colombian underage patient. | Cryptococcosis is a life-threatening mycosis reported mainly in human adults with low frequency in children. High mortality rates may occur in cases with late diagnosis therefore, a timely suspicion of this pathology is important. Cryptococcus gattii is the less prevalent species complex predominantly isolated from app... | ['Antifungal Agents', 'Cerebrospinal Fluid', 'Child', 'Colombia', 'Cryptococcosis', 'Cryptococcus gattii', 'Humans', 'Male'] | 32,087,082 | [['D27.505.954.122.136'], ['A12.207.270.210'], ['M01.060.406'], ['Z01.107.757.284'], ['C01.150.703.248'], ['B01.300.381.258.300', 'B01.300.930.316.300'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding. | PPARs are members of the nuclear hormone receptor superfamily and are primarily involved in lipid metabolism. The expression patterns of all 3 PPAR isotypes in 22 adult rat organs were analyzed by a quantitative ribonuclease protection assay. The data obtained allowed comparison of the expression of each isotype to the... | ['Animals', 'DNA, Complementary', 'Eating', 'Fasting', 'Gene Expression Regulation', 'Molecular Sequence Data', 'Nuclear Proteins', 'Organ Specificity', 'Rats', 'Receptors, Cytoplasmic and Nuclear', 'Signal Transduction', 'Transcription Factors'] | 11,564,675 | [['B01.050'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G07.203.650.283', 'G10.261.330'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['G05.308'], ['L01.453.245.667'], ['D12.776.660'], ['G07.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.826']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The nature of adrenoceptors in the guinea pig cerebral cortex: a microiontophoretic study. | 1. Noradrenaline, isoprenaline, and phenylephrine have been applied my microiontophoresis to neurones in the guinea pig cerebral cortex. All three compounds produced depression of neuronal firing, and all could be antagonized to some extent by phentolamine or propranolol. 2. The responses to isoprenaline were substanti... | ['Animals', 'Cerebral Cortex', 'Guinea Pigs', 'Iontophoresis', 'Isoproterenol', 'Male', 'Neurons', 'Norepinephrine', 'Phentolamine', 'Phenylephrine', 'Propranolol', 'Receptors, Adrenergic'] | 597,789 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['B01.050.150.900.649.313.992.550'], ['E02.319.267.650', 'E05.301.300.575'], ['D02.033.100.291.439', 'D02.092.063.291.439', 'D02.092.311.649', 'D02.455.426.559.389.657.166.175.649'], ['A08.675', 'A11.671'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', ... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of insulin vs. glibenclamide in recently diagnosed patients with type 2 diabetes: a 4-year follow-up. | AIM: To compare effects of early insulin vs. glibenclamide treatment on beta-cell function, metabolic control and quality of life (QL) in recently diagnosed patients with type 2 diabetes.METHODS: Forty-nine patients with type 2 diabetes diagnosed 0-2 years before inclusion were randomized to two daily injections of pre... | ['Adult', 'Aged', 'Blood Glucose', 'Body Weight', 'C-Peptide', 'Diabetes Mellitus, Type 2', 'Drug Administration Schedule', 'Fasting', 'Female', 'Follow-Up Studies', 'Glucagon', 'Glyburide', 'Glycated Hemoglobin A', 'Health Status Indicators', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Insulin, Long-Acting', 'Insulin... | 17,394,534 | [['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['C18.452.394.750.149', 'C19.246.300'], ['E02.319.283'], ['F01.145.407.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Huma... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Pre-designed consent forms for total hip replacement, total knee replacement, and caesarean section: A national observational study of current English practice. | BACKGROUND: Pre-designed procedure-specific consent forms (PCFs) have potential advantages over handwritten forms for improving the consent process and disclosing material risks, as necessitated by the 2015 'Montgomery' ruling. We aimed to assess the use and quality of English NHS Trust PCFs for total hip replacement (... | ['Arthroplasty, Replacement, Hip', 'Arthroplasty, Replacement, Knee', 'Cesarean Section', 'Consent Forms', 'England', 'Female', 'Humans', 'Male', 'Pregnancy', 'State Medicine'] | 30,058,533 | [['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E04.520.252.500'], ['I01.880.604.583.427.134', 'N03.706.535.489.134', 'N04.452.859.198', 'N05.715.360.300.715.245'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Evaluation of Effective Microorganisms on home scale organic waste composting. | Home composting can be an effective way to reduce the volume of municipal solid waste. The aim of this study is to evaluate the effect of Effective Microorganism™ (EM) for the home scale co-composting of food waste, rice bran and dried leaves. A general consensus is lacking regarding the efficiency of inoculation compo... | ['Composting', 'Escherichia coli', 'Humic Substances', 'Soil', 'Solid Waste'] | 28,427,880 | [['N06.850.780.200.800.800.700.500', 'N06.850.860.510.900.600.200'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D02.241.444', 'D02.455.426.559.389.657.377', 'D20.721.500'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D20.944.730', 'N06.850.460.710.730']] | ['Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Wave pattern of ground reaction force of growing children. | We studied the free gait of children by analyzing the wave pattern of the ground reaction force (GRF) and measuring time and distance parameters using large force plates. Two hundred and forty-one normal children, age 4-10 years, were included. Normalized waves of each subject were obtained by computer. Waves are compo... | ['Age Factors', 'Child', 'Child, Preschool', 'Female', 'Gait', 'Humans', 'Male', 'Reference Values', 'Signal Processing, Computer-Assisted', 'Time Factors'] | 1,613,100 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.978.810'], ['L01.224.800'], ['G01.910.857']] | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Study on the prevalence of arthritis and relevant factors in Shanghai]. | OBJECTIVE: This study aimed to understand the prevalence rate, epidemiological characteristics and relevant factors of arthritis in Shanghai.METHODS: A sample of 7 575 residents aged 15 years and above was drawn from 6 communities under multiple stage cluster sampling. A household survey with questionnaire was carried ... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Arthritis', 'China', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Risk Factors', 'Sex Factors', 'Social Class', 'Socioeconomic Factors'] | 14,761,634 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C05.550.114'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A comparison of slow release with conventional oxprenolol: plasma concentrations and clinical effects. | 1 Plasma concentrations of oxprenolol have been compared in six healthy volunteers after 80 and 160 mg doses of a new slow release (SR) oxprenolol preparation, after an 80 ng dose of conventional oxprenolol (CO), and after the second of two 80 mg doses of conventional oxprenolol given 12 h apart. Basal pulse rates and ... | ['Administration, Oral', 'Adult', 'Blood Pressure', 'Clinical Trials as Topic', 'Delayed-Action Preparations', 'Humans', 'Male', 'Oxprenolol', 'Physical Exertion', 'Pulse', 'Time Factors'] | 788,749 | [['E02.319.267.100'], ['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D26.255.210', 'E02.319.300.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.100.624.698.633', 'D02.033.755.624.698.633', 'D02.092.063.624.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
3D Volumetric Measurement of Neurofibromatosis Type 2-Associated Meningiomas: Association Between Tumor Location and Growth Rate. | OBJECTIVE: Treatment of meningiomas in neurofibromatosis type II (NF2) patients is challenging because the natural history of these tumors is unclear. More insight in tumor growth and factors predicting growth may contribute to a better clinical management. In this study, growth characteristics of supratentorial NF-rel... | ['Adult', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Humans', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Male', 'Meningioma', 'Neurofibromatosis 2', 'Neuroimaging', 'Neurosurgical Procedures', 'Skull Base'] | 26,087,434 | [['M01.060.116'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500'], ['C04.557.580.520', 'C04.557.645.520', 'C04.588.614.250.580.500', 'C10.551.2... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Cattle ticks from the Waterberg district of the Transvaal. | Macroscopically visible ticks were collected from the hides of 28 cattle slaughtered in pairs during a period of 14 months in the Waterberg District. In order of prevalence Rhipicephalus appendiculatus, Rhipicephalus evertsi evertsi, Amblyomma hebraeum, Hyalomma marginatum rufipes, Ixodes cavipalpus, Hyalomma truncatum... | ['Animals', 'Cattle', 'Seasons', 'South Africa', 'Ticks'] | 7,452,655 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['Z01.058.290.175.735'], ['B01.050.500.131.166.132.832']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Urinary surge of human luteinizing hormone in infertile women. | An improved semiquantitative immunoassay method allows human luteinizing hormone (hLH) in urine to be detected from 2.5 to 640 mIU/ml has developed. With this method, the hLH surges in every 3 h urine samples while awake were measured in 8 normal and 12 infertile women. The result was that the urinary hLH surge in infe... | ['Adult', 'Estradiol', 'Female', 'Gonadotropin-Releasing Hormone', 'Humans', 'Immunoassay', 'Infertility, Female', 'Luteinizing Hormone', 'Menstrual Cycle', 'Pituitary Gland', 'Pregnanediol'] | 1,972,101 | [['M01.060.116'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['C13.351.500.365.700'], ['D06.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Total haemoglobin mass and red blood cell profile in endurance-trained and non-endurance-trained adolescent athletes. | To evaluate differences in total haemoglobin mass (tHb mass) and in red blood cell profile between elite endurance-trained (END) and non-endurance-trained (nEND) male and female adolescent athletes, tHb mass (CO rebreathing) and specific variables of red blood cell profile (haemoglobin concentration, haematocrit, eryth... | ['Adolescent', 'Athletes', 'Athletic Performance', 'Cross-Sectional Studies', 'Environmental Monitoring', 'Erythrocyte Indices', 'Erythrocytes', 'Exercise Test', 'Female', 'Hematocrit', 'Hemoglobins', 'Humans', 'Longitudinal Studies', 'Male', 'Physical Education and Training', 'Physical Endurance', 'Sports', 'Young Adu... | 21,431,423 | [['M01.060.057'], ['M01.072'], ['I03.450.642.845.054'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N06.850.460.350.080', 'N06.850.780.375'], ['E01.370.225.625.230', 'E05.200.625.230', 'G09.188.260'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E01.370.370.380.250', 'E01.37... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The safety climate and its relationship to safety practices, safety of the work environment and occupational accidents in eight wood-processing companies. | Employees continuously observe their work environment and the actions of their fellow workers and superiors, and they use such observations as a basis for the creation of cognitive models associated with safety. These models regulate their actions in the workplace and thus have an influence on safety. This study attemp... | ['Accidents, Occupational', 'Finland', 'Humans', 'Safety', 'Surveys and Questionnaires', 'Wood'] | 10,994,603 | [['N06.850.135.240'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.135.060.075'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['A18.450.500.500', 'J01.637.241.900']] | ['Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Tooth loss, hypertension and risk for stroke in a Korean population. | Tooth loss has been suggested as a potential risk factor for stroke. We conducted a prospective cohort study of stroke in Korea on hypertension, diabetes, smoking, and tooth loss to characterize their independent effects and interactions. The overall risk of stroke and the risk of different subtypes of stroke were eval... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Female', 'Follow-Up Studies', 'Humans', 'Hypertension', 'Korea', 'Male', 'Middle Aged', 'Prevalence', 'Proportional Hazards Models', 'Risk', 'Stroke', 'Tooth Loss', 'Treatment Outcome'] | 19,013,571 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['Z01.252.474.557', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
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