Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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A left ventricular end-diastolic dimension less than 6.0 cm is associated with mortality after implantation of an axial-flow pump. | OBJECTIVE: The effects of having a lower left ventricular end-diastolic dimension before HeartMate II (Thoratec Corp, Pleasanton, Calif) left ventricular assist device implantation remain unclear. We analyzed our single-center data on HeartMate II implantation to determine whether having a lower left ventricular end-di... | ['Diastole', 'Female', 'Heart Ventricles', 'Heart-Assist Devices', 'Humans', 'Male', 'Proportional Hazards Models', 'Prosthesis Implantation', 'Retrospective Studies', 'Survival Analysis', 'Ventricular Dysfunction, Left', 'Ventricular Function'] | 30,797,583 | [['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['A07.541.560'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.740.998.825', 'E05.599.835.900', 'N05.715.360.75... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Analysis of corticosteroids by high performance liquid chromatography-electrospray mass spectrometry. | A high performance liquid chromatography electrospray mass spectrometry (HPLC-ESI-MS) method, for the detection of corticosteroids in cosmetics has been developed. A water-acetonitrile linear gradient on a C-18 reversed-phase column was found to be suitable in separating triamcinolone and its main derivatives, which gr... | ['Adrenal Cortex Hormones', 'Chromatography, High Pressure Liquid', 'Cosmetics', 'Illicit Drugs', 'Spectrometry, Mass, Electrospray Ionization'] | 15,284,915 | [['D06.472.040'], ['E05.196.181.400.300'], ['D27.720.269', 'J01.516.213'], ['D26.878'], ['E05.196.566.600']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Evaluation of infrared thermography compared to rectal temperature to identify illness in early postpartum dairy cows. | This study evaluated and compared infrared thermography (IRT) and rectal temperature (RT) as screening tests to identify sick transition dairy cows. Holstein cows (n = 72; 42 primiparous) had RT and IRT temperatures taken daily from 1 to 12 days in milk (DIM). Health examinations were performed daily to diagnose retain... | ['Animals', 'Body Temperature', 'Cattle', 'Cattle Diseases', 'Dairying', 'Female', 'Ketosis', 'Parturient Paresis', 'Placenta, Retained', 'Postpartum Period', 'Pregnancy', 'Thermography'] | 31,352,280 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['J01.040.246'], ['C18.452.076.176.652'], ['C22.695'], ['C13.703.590.767'], ['G08.686.702'], ['G08.686.784.769'], ['E01.370.350.800', 'E05.933.500']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Dopamine and serotonin metabolism associated with morphine reward and its inhibition with buspirone: A study in the rat striatum. | Adaptations within the nucleus accumbens (NAc) and caudate nucleus (CN) dopamine neurotransmission are involved in behavioral sensitization and enhanced incentive motivation towards drug paired stimuli which lead to drug addiction. Serotonin (5-hydroxytryptamine; 5-HT) can modulate dopamine neurotransmission to reduce ... | ['Animals', 'Buspirone', 'Caudate Nucleus', 'Corpus Striatum', 'Dopamine', 'Male', 'Morphine', 'Morphine Dependence', 'Nucleus Accumbens', 'Rats', 'Rats, Wistar', 'Receptor, Serotonin, 5-HT1A', 'Reward', 'Serotonin'] | 29,782,941 | [['B01.050'], ['D02.455.426.779.120', 'D03.383.606.210', 'D03.383.742.120', 'D04.711.120'], ['A08.186.211.200.885.287.249.487.550.184'], ['A08.186.211.200.885.287.249.487'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D03.132.577.249.562.571', 'D03.605.497.607.587', 'D03.633.400... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Calix[4]arenes featuring a direct lower rim attachment of dansyl groups. Synthesis, fluorescence properties and first report on crystal structures. | A series of new fluorescent calix[4]arenes (2-7; 5 has been isolated as two not yet described conformational isomers) featuring two directly lower rim attached dansyl moieties besides other lower or upper rim site substituents have been synthesized and investigated with reference to their fluorescence properties includ... | ['Calixarenes', 'Crystallography, X-Ray', 'Fluorescence', 'Models, Molecular', 'Molecular Structure', 'Phenols', 'Stereoisomerism'] | 19,907,781 | [['D04.345.025'], ['E05.196.309.742.225'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D02.455.426.559.389.657'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Flow cytometric analysis of internal calcium mobilization via a B2-bradykinin receptor on a subclone of PC-12 cells. | Single cell Ca2+ mobilization was studied by nonparametric, quantitative flow cytometry using a sort-selected subclone of PC-12 cells. The response of the parent PC-12 population to bradykinin (BK) was very heterogeneous and of a relatively low magnitude. Cells that exhibited maximal Ca2+ mobilization were singly sorte... | ['Adrenal Gland Neoplasms', 'Animals', 'Bradykinin', 'Calcium', 'Flow Cytometry', 'Pheochromocytoma', 'Receptors, Bradykinin', 'Receptors, Neurotransmitter', 'Rest', 'Tumor Cells, Cultured'] | 1,847,193 | [['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['B01.050'], ['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', 'D12.776.631.650.090', 'D23.469.050.375.110', 'D23.529.812.169'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Evaluation of safety and efficacy of DNA vaccines against bovine herpesvirus-1 (BoHV-1) in calves. | Four DNA vaccines against BoHV-1 were evaluated for their efficacy in calves. Twelve animals were divided into four groups which were injected with four different DNA vaccines: pVAX-tgD (Vaccine A); pVAX-tgD co-immunised with pVAX-48CpG (Vaccine B); pVAX-UbiLacI-tgD-L (Vaccine C); pVAX-UbiLacI-tgD-L co-immunised with p... | ['Animals', 'Antibodies, Neutralizing', 'Antibodies, Viral', 'Cattle', 'Enzyme-Linked Immunosorbent Assay', 'Herpesvirus 1, Bovine', 'Immunity, Humoral', 'Infectious Bovine Rhinotracheitis', 'Interferon-gamma', 'Lymph Nodes', 'Vaccines, DNA', 'Viral Proteins', 'Viral Vaccines', 'Virus Shedding'] | 19,906,427 | [['B01.050'], ['D12.776.124.486.485.114.244', 'D12.776.124.790.651.114.244', 'D12.776.377.715.548.114.244'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['B01.050.150.900.649.313.500.380.271'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of inhaled endotoxin on mucociliary clearance and airway inflammation in mild smokers and nonsmokers. | BACKGROUND: In healthy nonsmokers, inhaled endotoxin [lipopolysaccharide (LPS)] challenge induces airway neutrophilia and modifies innate immune responses, but the effect on mucociliary clearance (MCC), a key host defense response, is unknown. Although smokers are chronically exposed to LPS through inhaled tobacco smok... | ['Administration, Inhalation', 'Adult', 'Endotoxins', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mucociliary Clearance', 'Neutrophil Infiltration', 'North Carolina', 'Pneumonia', 'Respiratory Mucosa', 'Risk Assessment', 'Smoking', 'Spirometry', 'Time Factors', 'Young Adult'] | 24,568,613 | [['E02.319.267.050'], ['M01.060.116'], ['D23.946.123.329'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.386.520', 'G09.772.555'], ['G12.632'], ['Z01.107.567.875.075.475', 'Z01.107.567.875.750.530'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['A04.760', 'A10.615.550.760'], ['E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Make the pledge. | The first NHS Change Day in 2013, began with a Twitter conservation between clinicians. This year's March 3 event aims to attract 5000.000 pledges. The day harnesses individuals' passion for the NHS using voluntary commitments to implement (mostly) small, simple measures. | ['Internationality', 'Nursing Staff', 'Quality of Health Care', 'Social Networking', 'State Medicine', 'United Kingdom'] | 24,568,401 | [['I01.615'], ['M01.526.485.680', 'N02.360.680'], ['N04.761', 'N05.715'], ['L01.143.910'], ['N03.349.550.902', 'N03.858'], ['Z01.542.363']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Health Care [N]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Enterococcus faecalis type strain leakage through root canals filled with Gutta-Percha/AH plus or Resilon/Epiphany. | The aim of this in vitro study was to compare leakage of Enterococcus faecalis ATCC 29212 through root canals of single-rooted extracted human mandibular premolars filled with either gutta-percha/AH Plus or Resilon/Epiphany using the continuous wave of condensation technique. Test and control teeth were suspended in an... | ['Dental Leakage', 'Enterococcus faecalis', 'Epoxy Resins', 'Gutta-Percha', 'Humans', 'Kaplan-Meier Estimate', 'Root Canal Filling Materials', 'Statistics, Nonparametric'] | 17,185,129 | [['C07.793.221'], ['B03.353.750.250.250.280', 'B03.510.550.250.250.280'], ['D05.750.716.822.461', 'D25.720.716.822.461', 'J01.637.051.720.716.822.461'], ['D20.215.721.061', 'D25.339.859.495', 'D25.720.327.840.119', 'J01.637.051.339.859.495'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Are invasive plants more competitive than native conspecifics? Patterns vary with competitors. | Invasive plants are sometimes considered to be more competitive than their native conspecifics, according to the prediction that the invader reallocates resources from defense to growth due to liberation of natural enemies ['Evolution of Increased Competitive Ability' (EICA) hypothesis]. However, the differences in com... | ['Ageratina', 'Biomass', 'China', 'Demography', 'Introduced Species', 'Mexico', 'Plant Physiological Phenomena'] | 26,489,964 | [['B01.650.940.800.575.912.250.100.046'], ['G16.500.275.157.100', 'N06.230.124.100'], ['Z01.252.474.164'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['Z01.107.567.589'], ['G15']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Low frequency of cytomegalovirus infection during exacerbations of inflammatory bowel diseases. | Although numerous reports have described inflammatory bowel diseases (IBDs) complicated with cytomegalovirus (CMV) infection, the virus participation as an exacerbating factor remains unclear. The aim of this study was thus to clarify the clinical significance of CMV infection complicating exacerbation and to correlate... | ['Adult', 'Biopsy', 'Colon', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'DNA, Viral', 'Female', 'Humans', 'Inflammatory Bowel Diseases', 'Intestinal Mucosa', 'Male', 'Middle Aged', 'Polymerase Chain Reaction', 'Prevalence', 'Retrospective Studies', 'Severity of Illness Index', 'Viral Load', 'Virology'] | 20,827,767 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['B04.280.382.150.150'], ['C01.925.256.466.245'], ['D13.444.308.568'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[The C-terminus of transcription factor TnrA from Bacillus subtilis controls DNA-binding domain activity but is not required for dimerization]. | The transcription factor ThrA, which belongs to the MerR transcription regulators, in Bacillus subtilis cells controls genes of nitrogen metabolism under conditions of nitrogen limitation. As all the DNA-binding proteins, it is present as a dimer in cells, but the dimerization site is still unknown. The multiple alignm... | ['Amino Acid Sequence', 'Bacillus subtilis', 'Bacterial Proteins', 'DNA-Binding Proteins', 'Molecular Sequence Data', 'Mutation', 'Nitrogen', 'Protein Multimerization', 'Protein Structure, Tertiary', 'Repressor Proteins', 'Sequence Alignment', 'Surface Plasmon Resonance'] | 23,808,168 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['D12.776.260'], ['L01.453.245.667'], ['G05.365.590'], ['D01.268.604', 'D01.362.625'], ['G02.111.694'], ['G02... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Omission of aspirin in patients following coronary artery bypass graft surgery. | Graft patency is a major factor contributing to the long-term results of coronary artery bypass graft (CABG) surgery. The systematic overview of the Antiplatelet Trialists' Collaboration provides unequivocal evidence that antiplatelet therapy reduces by nearly one-half the odds of coronary graft occlusion following CAB... | ['Anticoagulants', 'Aspirin', 'Coronary Artery Bypass', 'Drug Administration Schedule', 'Follow-Up Studies', 'Graft Occlusion, Vascular', 'Humans', 'Vascular Patency', 'Warfarin'] | 7,876,370 | [['D27.505.954.502.119'], ['D02.455.426.559.389.657.410.595.176'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E02.319.283'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C23.550.767.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ecological structure and the distribution of schizophrenia and affective psychoses in Nottingham. | The 800 census enumeration districts of Nottingham were used as a basis for the production of 12 distinct 'clusters' or neighbourhood types. Plotting the place of residence of the 68 patients with 'certain' or 'very likely' diagnoses of ICD-9 schizophrenia, identified in the World Health Organization Study of Determina... | ['Adult', 'Affective Disorders, Psychotic', 'England', 'Housing', 'Humans', 'Residence Characteristics', 'Schizophrenia', 'Social Class'] | 3,446,306 | [['M01.060.116'], ['F03.700.150'], ['Z01.542.363.300'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.850.505.400.800.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.224.791', 'N06.850.505.400.800'], ['F03.700.750'], ['I01.880.853.996.755', 'N01.824.782']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Pre-translational regulation of neutrophil L-selectin in glucocorticoid-challenged cattle. | L-selectin (CD62L) gene expression in neutrophils is commonly referred to as "constitutive" because circulating neutrophils require a constant supply of this adhesion molecule for continuous trafficking into peripheral tissues. Under normal circumstances, marginating blood neutrophils and neutrophils that become activa... | ['Actins', 'Animals', 'Blotting, Northern', 'Cattle', 'DNA, Complementary', 'Dexamethasone', 'Down-Regulation', 'Estradiol', 'Female', 'Flow Cytometry', 'Gene Expression Regulation', 'Glucocorticoids', 'Hydrocortisone', 'L-Selectin', 'Male', 'Neutrophils', 'Polymerase Chain Reaction', 'Pregnancy', 'Progesterone', 'RNA,... | 11,730,931 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['G0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mechanism of the reduced elimination clearance of benzylpenicillin from cerebrospinal fluid in rats with intracisternal administration of lipopolysaccharide. | The mechanism responsible for the reduced clearance of benzylpenicillin (BPC) from the cerebrospinal fluid (CSF) was investigated in rats that received an intracisternal administration of lipopolysaccharide (LPS). BPC was intraventricularly injected and its elimination from the CSF studied. During the inflammation crea... | ['Algorithms', 'Animals', 'Brain', 'Cerebrospinal Fluid', 'Choroid Plexus', 'Cisterna Magna', 'Formycins', 'Leukocyte Count', 'Lipopolysaccharides', 'Male', 'Microinjections', 'Nitric Oxide', 'Nitrogen Oxides', 'Penicillin G', 'Penicillins', 'Rats', 'Rats, Sprague-Dawley', 'Taurine'] | 12,386,127 | [['G17.035', 'L01.224.050'], ['B01.050'], ['A08.186.211'], ['A12.207.270.210'], ['A08.186.211.140.298'], ['A08.186.566.166.686.351'], ['D03.383.742.680.350', 'D13.570.685.350', 'D13.570.800.410'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Simple techniques to reduce bowel activity in cardiac SPECT imaging. | BACKGROUND AND AIM: Scatter from the bowel degrades image quality in 99mTc sestamibi myocardial perfusion imaging (MPI). Iodinated oral contrast, which has been used to outline bowel in medical imaging, absorbs X-rays as well as gamma rays. The purpose of this study was to test our hypothesis that iodinated oral contra... | ['Adenosine', 'Administration, Oral', 'Aged', 'Contrast Media', 'Female', 'Gamma Rays', 'Heart Ventricles', 'Humans', 'Image Processing, Computer-Assisted', 'Intestines', 'Male', 'Middle Aged', 'Myocardial Reperfusion', 'Myocardium', 'Radiopharmaceuticals', 'Reproducibility of Results', 'Technetium Tc 99m Sestamibi', '... | 15,097,809 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['E02.319.267.100'], ['M01.060.116.100'], ['D27.505.259.500', 'D27.720.259'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['A03.556.124'], ['M01.060.1... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Circular dichroism studies of myoglobin and leghemoglobin. | The circular dichroism spectra of leghemoglobin a from the root nodules of soybean have been compared with those for sperm whale myoglobin in the fat- and near-ultraviolet and the Soret and visible regions of the spectrum. Circular dichroism spectra in the far-ultraviolet show that the leghemoglobins all have a high al... | ['Animals', 'Apoproteins', 'Binding Sites', 'Carbon Monoxide', 'Circular Dichroism', 'Cyanides', 'Heme', 'Hemeproteins', 'Leghemoglobin', 'Myoglobin', 'Nicotine', 'Oxidation-Reduction', 'Oxygen', 'Protein Binding', 'Protein Conformation', 'Soybeans', 'Species Specificity', 'Spectrophotometry', 'Spectrophotometry, Ultra... | 1,238,108 | [['B01.050'], ['D12.776.070'], ['G02.111.570.120'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['E05.196.867.151'], ['D01.248.497.158.291', 'D01.625.400.100'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D12.776.422'], ['D12.776.422.316... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The contribution of surface residues to membrane binding and ligand transfer by the á-tocopherol transfer protein (á-TTP). | Previous work has shown that the á-tocopherol transfer protein (á-TTP) can bind to vesicular or immobilized phospholipid membranes. Revealing the molecular mechanisms by which á-TTP associates with membranes is thought to be critical to understanding its function and role in the secretion of tocopherol from hepatocytes... | ['Amino Acid Sequence', 'Amino Acid Substitution', 'Base Sequence', 'Binding Sites', 'Carrier Proteins', 'DNA Primers', 'Hep G2 Cells', 'Hepatocytes', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'In Vitro Techniques', 'Ligands', 'Lipid Bilayers', 'Models, Molecular', 'Molecular Sequence Data', 'Mutagenesis, S... | 21,110,980 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D12.776.157'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['A11.251.860.180.432', 'A11.436.348.500'], ['A11.436.348'], ['B01.050.150.900... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Infectious crystalline keratopathy due to Streptococcus pneumoniae. Possible association with serotype. | BACKGROUND: Infectious crystalline keratopathy is a distinctive clinical entity characterized by bacterial replication within the corena without inflammation. The authors report on a patient with infectious crystalline keratopathy due to Streptococcus pneumoniae serotype 11F. They used this isolate to study the contrib... | ['Aged', 'Animals', 'Corneal Stroma', 'Eye Infections, Bacterial', 'Humans', 'Keratitis', 'Male', 'Microbiological Techniques', 'Pneumococcal Infections', 'Rabbits', 'Serotyping', 'Streptococcus pneumoniae'] | 8,008,339 | [['M01.060.116.100'], ['B01.050'], ['A09.371.060.217.228'], ['C01.150.252.289', 'C01.375.354', 'C11.294.354'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.204.564'], ['E01.370.225.875', 'E05.200.875'], ['C01.150.252.410.890.670'], ['B01.050.150.900.649.313.968.700'], ['E01.370.225.812.742', 'E01.370.225.875.... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Effect of histamine and pentagastrin on the functional state of the hypothalamo-neurohypophyseal secretory system]. | Histochemistry, cario- and zytometry methods showed that the activators of gastric secretion (histamine and pentagastrine) exerted opposite effects upon functional state of hypothalamo-neurohypophyseal secretory system in the guinea-pigs. Histamine (4 mg/kg) activated the system and induced the development of gastric m... | ['Animals', 'Cytoplasmic Granules', 'Guinea Pigs', 'Histamine', 'Hypothalamo-Hypophyseal System', 'Neurosecretion', 'Paraventricular Hypothalamic Nucleus', 'Pentagastrin', 'Supraoptic Nucleus'] | 710,632 | [['B01.050'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['B01.050.150.900.649.313.992.550'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['A06.688.357', 'A08.186.211.180.497.352.435', 'A08.186.211.200.317.357.352.435', 'A08.713.357'], ['G11.561.653'], ['A0... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Native and paced QRS duration in right ventricular apex paced patients. | BACKGROUND: The value between paced QRS duration (pQRSd) and native QRS duration (nQRSd) in paced population has not been compared. The relation between nQRSd and pQRSd remains undefined now.METHODS AND RESULTS: A total of 310 right ventricular apex (RVA) paced patients were enrolled. The correlation coefficients betwe... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Bundle-Branch Block', 'Cardiac Pacing, Artificial', 'Cohort Studies', 'Echocardiography, Doppler', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Heart Block', 'Heart Failure', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Risk Factors', 'Severity of Illness... | 20,206,899 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.067.558.323', 'C14.280.123.500.323', 'C23.550.073.425.100'], ['E02.331.200'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.35... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Feeding low-fat milk during infancy. | Despite the widespread agreement that low-fat milk should not be used during infancy, there is a sizable portion of infants in the United States who were fed a diet that included low-fat milk (less than or equal to 2% fat). In 1985, 14% of infants 8 months old, 20% of infants 10 months old, and 32% of infants 12 months... | ['Animals', 'Dietary Fats', 'Humans', 'Infant', 'Infant Food', 'Infant Nutritional Physiological Phenomena', 'Milk', 'Nutrition Surveys', 'Nutritional Requirements', 'Surveys and Questionnaires', 'United States'] | 3,661,691 | [['B01.050'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G07.203.300.525.500', 'J02.500.525.500'], ['G07.203.650.220.500'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['E05.318.308.98... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Recognition of emotions from visual and prosodic cues in Parkinson's disease. | OBJECTIVE: To assess whether Parkinson Disease (PD) patients are impaired at perceiving emotions from facial and prosodic cues and whether any putative defective performance concerns recognition of a particular emotion.BACKGROUND: Braak et al. [1] demonstrated that in different stages PD pathology involves the nigrostr... | ['Affect', 'Affective Symptoms', 'Aged', 'Cues', 'Discrimination, Psychological', 'Emotions', 'Facial Expression', 'Female', 'Humans', 'Language Tests', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Parkinson Disease', 'Pattern Recognition, Visual', 'Perceptual Disorders', 'Photic Stimulation', 'Recognition, Psyc... | 18,810,595 | [['F01.470.047'], ['F01.145.126.100'], ['M01.060.116.100'], ['F02.463.425.234'], ['F02.463.593.257'], ['F01.470'], ['E01.370.600.225', 'F01.145.209.530.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.240'], ['M01.060.116.630'], ['F04.711.513'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of elevated CO2 concentration on photosynthetic characteristics of hyperaccumulator Sedum alfredii under cadmium stress. | The combined effects of elevated CO2 and cadmium (Cd) on photosynthetic rate, chlorophyll fluorescence and Cd accumulation in hyperaccumulator Sedum alfredii Hance were investigated to predict plant growth under Cd stress with rising atmospheric CO2 concentration. Both pot and hydroponic experiments were conducted and ... | ['Biomass', 'Cadmium', 'Carbon Dioxide', 'Chlorophyll', 'Fluorescence', 'Gases', 'Light', 'Photosynthesis', 'Photosystem II Protein Complex', 'Plant Shoots', 'Plant Transpiration', 'Sedum', 'Stress, Physiological'] | 25,370,532 | [['G16.500.275.157.100', 'N06.230.124.100'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D01.362'], ['G01.358.500.505.650', '... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Chemiluminescent detection for capillary electrophoresis and EMMA enzyme assays. | A large number of analytically and physiologically significant enzymes produce or consume hydrogen peroxide (H2O2). Post-column reaction of H2O2 with luminol in an alkaline solution results in chemiluminescence. A prototype reactor/detector for CE with chemiluminescent detection (CLD) of H2O2 was constructed and utiliz... | ['Catalase', 'Electrophoresis, Capillary', 'Galactose Oxidase', 'Glucose Oxidase', 'Hydrogen Peroxide', 'Indicators and Reagents', 'Luminescent Measurements', 'Luminol', 'Microchemistry', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 9,384,743 | [['D08.811.682.732.332'], ['E05.196.401.190', 'E05.301.300.190'], ['D08.811.682.047.210'], ['D08.811.682.047.239'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D27.720.470.410'], ['E05.196.712.516'], ['D03.383.710.350'], ['E05.196.620', 'H01.181.650'], ['E05.318.3... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
A plea for more comprehensive blood pressure measurements when evaluating drug treatment of hypertension. | Blood pressure was studied at rest, continuously for 24 h and during dynamic and isometric exercise in previously untreated males with documented mild hypertension. The antihypertensive efficacy of atenolol was compared with that of enalapril in a randomized, double-blind, crossover study, in order to elucidate whether... | ['Atenolol', 'Blood Pressure', 'Blood Pressure Determination', 'Clinical Trials as Topic', 'Double-Blind Method', 'Enalapril', 'Exercise', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Random Allocation'] | 2,851,626 | [['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140', 'E01.370.600.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.52... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Multiple sclerosis without treatment: characteristic features of 70 untreated patients in a cohort of 1187 patients]. | INTRODUCTION: First treatment protocols for multiple sclerosis (MS) have been established in France for over 15 years. Presently, a large majority of patients are treated, or has been treated in the past years, with one or more disease modifying drugs. However, despite a long-term follow-up, a certain patients remain u... | ['Adult', 'Aged', 'Cohort Studies', 'Comorbidity', 'Disease Progression', 'Female', 'Follow-Up Studies', 'France', 'Humans', 'Male', 'Middle Aged', 'Multiple Sclerosis', 'Retrospective Studies', 'Socioeconomic Factors', 'Treatment Refusal', 'Watchful Waiting'] | 22,341,991 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
In vivo model for frontal sinus and calvarial bone defect obliteration with bioactive glass S53P4 and hydroxyapatite. | An in vivo model was developed to investigate the usability of a frontal sinus and a calvarial bone defect obliteration with bioactive glass S53P4 (BG) and hydroxyapatite (HA) granules. Roofs of 21 Elco rabbit frontal sinuses were drilled open from 4 separate holes using a standard method, and the sinuses, located in p... | ['Animals', 'Biocompatible Materials', 'Durapatite', 'Electron Probe Microanalysis', 'Frontal Sinus', 'Glass', 'Male', 'Materials Testing', 'Microscopy, Electron, Scanning', 'Models, Animal', 'Rabbits', 'Radiography', 'Skull'] | 11,319,739 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['E01.370.350.515.402.250', 'E05.196.867.800.360', 'E05.595.402.250', 'E05.799.830.360'], ['A04.531.621.387'], ['J01.637.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Criterion for amino acid composition of defensins and antimicrobial peptides based on geometry of membrane destabilization. | Defensins comprise a potent class of membrane disruptive antimicrobial peptides (AMPs) with well-characterized broad spectrum and selective microbicidal effects. By using high-resolution synchrotron small-angle X-ray scattering to investigate interactions between heterogeneous membranes and members of the defensin subf... | ['Amino Acid Sequence', 'Animals', 'Arginine', 'Bacteria', 'Cell Membrane', 'Cell Membrane Permeability', 'Defensins', 'Liposomes', 'Scattering, Small Angle', 'X-Ray Diffraction'] | 21,473,577 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['B03'], ['A11.284.149'], ['G03.143.335', 'G04.175'], ['D12.644.050.200', 'D12.776.543.695.054.200'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['E05.196.822.830',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Predictors of non-attendance from BreastScreen NSW in women who report current mammography screening. | OBJECTIVE: To identify among self-reported current screeners: (1) predictors of never attendance at BreastScreen NSW (BSNSW); (2) predictors of late or lapsed attendance to BSNSW (attendance to alternative providers).METHODS: Random samples of women aged 50-69 years were selected from the BSNSW database and NSW elector... | ['Aged', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Status', 'Humans', 'Interviews as Topic', 'Mammography', 'Mass Screening', 'Middle Aged', 'New South Wales', 'Odds Ratio', 'Patient Acceptance of Health Care', 'Predictive Value of Tests', 'Self Disclosure', 'Socioeconomic Factors', 'Time Factors'] | 14,723,404 | [['M01.060.116.100'], ['F01.100.150.500', 'N05.300.150.410'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['E01.370.350.700.500'], ['E01.370.500', 'E05.318.308.980.438.580', ... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Eyewitness identification accuracy: a comparison of adults with and those without intellectual disabilities. | The effect of variation in the clarity of a witnessed event on the accuracy of eyewitness identification for adults with intellectual disabilities and those without disabilities was examined. Following observation of one of three films (clear, less distinct, or ambiguous) depicting a nonviolent theft, participants were... | ['Adolescent', 'Adult', 'Crime', 'Crime Victims', 'Female', 'Humans', 'Intellectual Disability', 'Male', 'Middle Aged', 'Repression, Psychology'] | 12,737,610 | [['M01.060.057'], ['M01.060.116'], ['I01.198.240', 'I01.880.735.191'], ['M01.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['M01.060.116.630'], ['F01.393.821']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Report of the 2005 STS Congenital Heart Surgery Practice and Manpower Survey. | BACKGROUND: Limited information is available concerning the congenital heart surgery workforce in North America. To obtain reliable data, The Society of Thoracic Surgeons (STS) Workforce on Congenital Heart Surgery undertook a subspecialty focused survey.METHODS: Preliminary research of websites and databases revealed ... | ['Adult', 'Aged', 'Attitude of Health Personnel', 'Canada', 'Data Collection', 'Education, Medical, Graduate', 'Faculty, Medical', 'Female', 'Foreign Medical Graduates', 'Heart Defects, Congenital', 'Humans', 'Job Satisfaction', 'Male', 'Middle Aged', 'Physicians', 'Professional Practice', 'Schools, Medical', 'Societie... | 16,928,571 | [['M01.060.116'], ['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['Z01.107.567.176'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['I02.358.337.350', 'I02.358.399.350'], ['M01.526.485.375', 'M01.526.702.250.373', 'N02.360.375'], ['M01.526.407.435', 'M01.526.485.810.390', 'N02.360.810.390... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
C677T mutation of the methylenetetrahydrofolate reductase gene among the Korean infants in Seoul city. | The missense mutation, C677T (Ala--->Val), in the methylenetetrahydrofolate reductase (MTHFR) gene, is related to hyperhomocysteinemia and is regarded as a risk factor for coronary artery disease and neural tube defects. The prevalence of this mutation was reported to differ among various ethnic groups, but there are f... | ['Adult', 'Asian Continental Ancestry Group', 'Base Sequence', 'Chi-Square Distribution', 'DNA', 'Female', 'Gene Frequency', 'Genetics, Population', 'Genotype', 'Humans', 'Infant', 'Korea', 'Male', 'Methylenetetrahydrofolate Reductase (NADPH2)', 'Molecular Sequence Data', 'Mutation, Missense', 'Oxidoreductases Acting o... | 10,985,160 | [['M01.060.116'], ['M01.686.508.200'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['D13.444.308'], ['G05.330'], ['H01.158.273.343.335'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.7... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis. | BACKGROUND: The spread of antibiotic-resistant bacteria poses a substantial threat to morbidity and mortality worldwide. Due to its large public health and societal implications, multidrug-resistant tuberculosis has been long regarded by WHO as a global priority for investment in new drugs. In 2016, WHO was requested b... | ['Anti-Bacterial Agents', 'Drug Resistance, Bacterial', 'Humans', 'Tuberculosis', 'World Health Organization'] | 29,276,051 | [['D27.505.954.122.085'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.040.552.846'], ['N03.540.514.718.800']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Scapular hydatidosis with extraosseous involvement]. | A forty three-year-old female, born in a rural area of southern Chile, at the age of 30 presented pain and limitation of motility of the right shoulder. Later on, she presented an increasing of volume at the right scapular region. A radiography showed an osteolytic lesion of the scapula. In a biopsy an osseous hydatido... | ['Adult', 'Bone Diseases', 'Echinococcosis', 'Female', 'Humans', 'Scapula', 'Tomography, X-Ray Computed'] | 11,338,976 | [['M01.060.116'], ['C05.116'], ['C01.610.335.190.396'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.087.783'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Visuomotor performance in Blacks. | The performance of Black hospital employees in the copying of designs, the drawing of human figures, and the assembling of blocks, is discussed. They performed the latter two tasks poorly. This may be attributable to their culture but it emphasises the unsuitability of these tests for Blacks, in that they are not stand... | ['Adult', 'African Americans', 'African Continental Ancestry Group', 'Bender-Gestalt Test', 'Brain Damage, Chronic', 'Culture', 'Ethnopsychology', 'Female', 'Humans', 'Intellectual Disability', 'Male', 'Middle Aged', 'Psychological Tests', 'South Africa'] | 1,188,533 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.686.508.100'], ['F04.711.513.180', 'F04.711.647.138'], ['C10.228.140.140'], ['I01.076.201.450', 'I01.880.853.100'], ['F04.096.544.275', 'F04.096.628.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Rapid and highly sensitive method for determination of methamphetamine and amphetamine in urine by electron-capture gas chromatography. | A rapid and sensitive method for determination of methamphetamine and amphetamine in urine was developed by using electron-capture gas chromatography. The extraction procedure, the experimental conditions for pentafluorobenzoyl derivative formation and the percentage recovery of the drugs from urine are described. The ... | ['Amphetamine', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Methamphetamine', 'Reference Values'] | 7,068,795 | [['D02.092.471.683.152.110'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.471.683.152.619'], ['E05.978.810']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Strongyloides stercoralis-hookworms association as a path to the estimation of the global burden of strongyloidiasis: A systematic review. | TRIAL REGISTRATION: PROSPERO (registration code CRD42019131127). | ['Animals', 'Global Burden of Disease', 'Humans', 'Soil', 'Strongyloides stercoralis', 'Strongyloidiasis'] | 32,282,827 | [['B01.050'], ['N05.425.184', 'N06.850.520.308.980.438.475.091'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['B01.050.500.500.294.400.875.640.680.700'], ['C01.610.335.508.700.700.799']] | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Patient perceptions of prandial oral therapy for type 2 diabetes. | PURPOSE: This survey was conducted to assess patient perceptions of glycemic control, convenience, and flexibility of a prescribed prandial oral therapy for type 2 diabetes mellitus.METHODS: Questionnaires distributed by physicians yielded baseline responses from 3696 patients who were beginning repaglinide treatment. ... | ['Administration, Oral', 'Adult', 'Aged', 'Attitude to Health', 'Carbamates', 'Diabetes Mellitus, Type 2', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Eating', 'Female', 'Humans', 'Hypoglycemia', 'Hypoglycemic Agents', 'Male', 'Metformin', 'Middle Aged', 'Piperidines', 'Surveys and Questionnaires'] | 12,212,016 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['F01.100.150', 'N05.300.150'], ['D02.241.081.251'], ['C18.452.394.750.149', 'C19.246.300'], ['E02.319.283'], ['E02.319.310'], ['G07.203.650.283', 'G10.261.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['D27.505.696.422'], ['D02.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chinese medicine for COVID-19: A protocol for systematic review and meta-analysis. | BACKGROUND: Coronavirus disease 2019 (COVID-19) is a respiratory illness that can spread from person to person. The virus that causes COVID-19 is a novel coronavirus that was first identified during an investigation into an outbreak in Wuhan, China. The clinical spectrum of SARS-CoV-2 infection appears to be wide, enco... | ['Betacoronavirus', 'COVID-19', 'Coronavirus Infections', 'Humans', 'Medicine, Chinese Traditional', 'Meta-Analysis as Topic', 'Pandemics', 'Pneumonia, Viral', 'SARS-CoV-2', 'Systematic Reviews as Topic'] | 32,569,196 | [['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], [... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Use of the Internet by Sudanese doctors and medical students. | Patterns of use of the Internet were investigated by a questionnaire survey of 102 hospital doctors and 123 medical students in Khartoum, Sudan, in January 2005. More doctors (84.3%) had used the Internet than had students (78.9%). Half of consultants (55.0%) used the Internet daily, compared with only 18.2% of junior ... | ['Adult', 'Attitude of Health Personnel', 'Attitude to Computers', 'Computer Literacy', 'Electronic Mail', 'Female', 'Health Knowledge, Attitudes, Practice', 'Hospitals, University', 'Humans', 'Information Services', 'Internet', 'Male', 'Medical Staff, Hospital', 'Middle Aged', 'Motivation', 'Periodicals as Topic', 'Pr... | 18,557,461 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['F01.100.100'], ['L01.143.256'], ['L01.178.847.249', 'L01.559.423.906.377.333'], ['F01.100.150.500', 'N05.300.150.410'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453'], ['L01.224.230.110.500'], ['M01.526.485... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Electrospinning of artemisinin-loaded core-shell fibers for inhibiting drug re-crystallization. | The main aim of this study was to inhibit the re-crystallization of a potent antimalarial drug, artemisinin (ART), by encapsulating it in core-shell fibers via a coaxially electrospun method. The ART-infiltrated cellulose acetate (CA) solution as the core material and poly(vinyl pyrrolidone) (PVP) solution as the shell... | ['Administration, Cutaneous', 'Animals', 'Antimalarials', 'Artemisinins', 'Calorimetry, Differential Scanning', 'Cellulose', 'Crystallization', 'Drug Carriers', 'Drug Compounding', 'Drug Storage', 'Electrochemical Techniques', 'Equipment Design', 'Humans', 'Nanofibers', 'Povidone', 'Skin', 'Skin Absorption', 'Spectrosc... | 23,565,867 | [['E02.319.267.120.060'], ['B01.050'], ['D27.505.954.122.250.100.085'], ['D01.248.497.158.685.750.212', 'D01.339.431.374.212', 'D01.650.550.750.200', 'D02.389.338.055', 'D02.455.849.765.211'], ['E05.196.131.310', 'E05.196.370.310'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Introduction of Functional Foods--Types, Manufacturing Methods and Quality Assurance]. | Because of the beneficial effects to health functional foods are important elements of health promotion. The positive effect of the functional components should be based on scientific evidence-based. In addition to the traditional food processing technology new technologies have appeared, e.g. microencapsulation, edibl... | ['Biological Availability', 'Drug Compounding', 'Edible Grain', 'Fermentation', 'Food Handling', 'Food Microbiology', 'Food Technology', 'Food, Organic', 'Functional Food', 'Humans', 'Nanotechnology', 'Prebiotics', 'Probiotics', 'Quality Control', 'Vacuum'] | 26,642,648 | [['G03.787.151', 'G07.690.725.129'], ['E05.916.270'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['G02.111.158.249', 'G03.191.249'], ['J01.576.423.200'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300',... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Susceptibilities of Actinobacillus actinomycetemcomitans biofilms to oral antiseptics. | The susceptibilities of Actinobacillus actinomycetemcomitans cultures, grown as 1- or 3-day-old biofilms or as planktonic suspensions, to concentrations of chlorhexidine digluconate, cetylpyridinium chloride or triclosan used in commercial mouthwashes were compared. Three-day biofilms were the most resistant form of th... | ['Aggregatibacter actinomycetemcomitans', 'Animals', 'Anti-Infective Agents, Local', 'Benzoates', 'Biofilms', 'Cetylpyridinium', 'Chlorhexidine', 'Colony Count, Microbial', 'Humans', 'Microbial Sensitivity Tests', 'Mouthwashes', 'Sodium Dodecyl Sulfate', 'Triclosan'] | 9,152,040 | [['B03.440.450.600.224.500', 'B03.660.250.550.170.500'], ['B01.050'], ['D27.505.954.122.187'], ['D02.241.223.100', 'D02.455.426.559.389.127'], ['A20.593', 'G06.120'], ['D03.383.725.762.232'], ['D02.078.370.141.100'], ['E01.370.225.875.220', 'E05.200.875.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity. | MicroRNAs (miRNAs) and transcription factors (TFs) are primary metazoan gene regulators. Whereas much attention has focused on finding the targets of both miRNAs and TFs, the transcriptional networks that regulate miRNA expression remain largely unexplored. Here, we present the first genome-scale Caenorhabditis elegans... | ['Animals', 'Animals, Genetically Modified', 'Caenorhabditis elegans', 'Genome', 'MicroRNAs', 'Polymerase Chain Reaction', 'Transcription, Genetic'] | 18,794,350 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['B01.050.500.500.294.400.875.660.250.250'], ['G05.360.340'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['E05.393.620.500'], ['G02.111.873', 'G05.297.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Safety and efficacy of balloon angioplasty in symptomatic intracranial stenosis: A systematic review and meta-analysis. | BACKGROUND AND PURPOSE: Endovascular treatment is offered for symptomatic intracranial stenosis (ICS) when medical therapy fails. The purpose of this meta-analysis is to evaluate the risks and effectiveness of balloon angioplasty (BA) alone.MATERIALS AND METHODS: Systematic review and meta-analysis of all available art... | ['Angioplasty, Balloon', 'Brain Ischemia', 'Humans', 'Intracranial Arteriosclerosis', 'Outcome Assessment, Health Care', 'Postoperative Complications', 'Stroke', 'Treatment Outcome'] | 30,862,462 | [['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['C10.228.140.300.150', 'C14.907.253.092'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.800', 'C14.907.137.126.372', 'C14.907.253.560.350'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Treatment with low-dose cytokines reduces oxidative-mediated injury in perilesional keratinocytes from vitiligo skin. | BACKGROUND: Vitiligo is a systemic dermatological disorder characterized by the loss of skin pigmentation due to melanocyte injury or aberrant functioning. Recent data underline its multifactorial etiology with significant involvement of autoimmune and redox alterations. The major role in vitiligo cellular immunity is ... | ['Cell Survival', 'Cells, Cultured', 'Cytokines', 'Flow Cytometry', 'Humans', 'Keratinocytes', 'NADPH Oxidases', 'Oxidative Stress', 'Reactive Oxygen Species', 'Vitiligo'] | 26,051,876 | [['G04.346'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.409.500', 'A... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell cycle dynamics of mouse embryonic stem cells in the ground state and during transition to formative pluripotency. | Mouse embryonic stem cells (mESCs) can be maintained as homogeneous populations in the ground state of pluripotency. Release from this state in minimal conditions allows to obtain cells that resemble those of the early post-implantation epiblast, providing an important developmental model to study cell identity transit... | ['Animals', 'Cell Culture Techniques', 'Cell Cycle', 'Cell Differentiation', 'Cell Line', 'Cell Lineage', 'Cell Self Renewal', 'Embryo Implantation', 'Intravital Microscopy', 'Mice', 'Microscopy, Confocal', 'Mouse Embryonic Stem Cells', 'Pluripotent Stem Cells', 'Time-Lapse Imaging'] | 31,142,785 | [['B01.050'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.144'], ['G04.152'], ['A11.251.210'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['G04.144.220.235', 'G04.161.750.500.375', 'G05.113.415', 'G07.345.249.410.750.500.625'], ['G08.686.784... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
alpha-Difluoromethylornithine induces differentiation of a human embryonal carcinoma cell line in vitro. | Human embryonal carcinoma cells could serve as a useful model system for analysis of early human development. A limited number of human embryonal carcinoma cell lines have been generated from in vivo tumors. We report here that alpha-difluoromethylornithine, a specific enzyme-activated inhibitor of ornithine decarboxyl... | ['Actins', 'Cell Differentiation', 'Cell Line', 'Eflornithine', 'Embryonal Carcinoma Stem Cells', 'Humans', 'Neoplastic Stem Cells', 'Polyamines', 'Tretinoin'] | 3,096,321 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G04.152'], ['A11.251.210'], ['D12.125.068.665.340', 'D12.125.095.765.340'], ['A11.251.860.590', 'A11.872.650.500', 'A11.872.700.250.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.872.650'], ['D02.092.782'], ['D02.455.326.271.665.20... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of vaginal Lactobacillus Rhamnosus (Normogin®) in preventing Bacterial Vaginosis in women with history of recurrences, undergoing surgical menopause: a prospective pilot study. | BACKGROUND: Bacterial vaginosis (BV), a poly-microbial clinical syndrome, is the most common cause of vaginal symptoms among women. The recurrence rate of BV is up to 30% after traditional antimicrobial therapy. Lactobacillus rhamnosus vaginal tablets have demonstrated to be a reliable topical effective and safe treatm... | ['Female', 'Humans', 'Lactobacillus rhamnosus', 'Menopause', 'Middle Aged', 'Pilot Projects', 'Prospective Studies', 'Recurrence', 'Vagina', 'Vaginosis, Bacterial'] | 23,740,456 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.353.750.450.475.700', 'B03.510.460.400.410.475.475.700', 'B03.510.550.450.475.700'], ['G08.686.157.500', 'G08.686.841.249.500'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E05.318.372.500.750.625', 'N05... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Nano TiO2 modification of bamboo and its antibacterial and mildew resistance performance]. | Bamboo, a kind of forest resources only less important than wood, is especially easy to mildew during outdoor service. In this work, TiO2 sols were synthesized under low-temperature condition by sol-gel method. The crystalline TiO2 film with a diameter of approximate 40-90 nm was used to coat bamboo at low temperature.... | ['Anti-Bacterial Agents', 'Bambusa', 'Escherichia coli', 'Fungicides, Industrial', 'Metal Nanoparticles', 'Titanium', 'X-Ray Diffraction'] | 20,545,161 | [['D27.505.954.122.085'], ['B01.650.940.800.575.912.250.822.066'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D27.720.031.700.288', 'D27.888.723.288'], ['J01.637.512.600.500'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Biotransformation of (+)-catechin into taxifolin by a two-step oxidation: primary stage of (+)-catechin metabolism by a novel (+)-catechin-degrading bacteria, Burkholderia sp. KTC-1, isolated from tropical peat. | Peat contains various persistent compounds derived from plant materials. We isolated a novel (+)-catechin-degrading bacterium, Burkholderia sp. KTC-1 (KTC-1), as an example of a bacterium capable of degrading persistent aromatic compounds present in tropical peat. This bacterium was isolated by an enrichment technique ... | ['Biotransformation', 'Burkholderia', 'Catechin', 'Flavonols', 'Oxidation-Reduction', 'Quercetin', 'Soil Microbiology', 'Species Specificity'] | 18,068,670 | [['G03.171', 'G03.787.225', 'G07.690.725.225'], ['B03.660.075.090.688.100'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['D03.383.663.283.266.450.284', 'D03.633.100.150.266.450.284'], ['G02.700', 'G03.295.531'], ['D03.383.663.283.266.450.284.777... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Vaccines Europe 2009. | The Informa Life Sciences vaccines conference is an annual meeting of a relatively small number of academics and industrialists. It is split into three concurrent sessions covering vaccine discovery, quality and manufacturing. Although there were many presentations of merit, only a few will be discussed here, including... | ['Antigens, Neoplasm', 'Cancer Vaccines', 'Europe', 'Humans', 'Influenza Vaccines', 'Virion'] | 20,109,022 | [['D23.050.285'], ['D20.215.894.200'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.899.302'], ['A21.249']] | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Multiple sulfatase deficiency in a Turkish family resulting from a novel mutation. | Multiple sulfatase deficiency (MSD) is an inherited lysosomal storage disease that affects post-translational activation of all of the sulfatases. Since biochemical and clinical findings are variable, the diagnosis is difficult in most of the cases. Missense, nonsense, microdeletion and splicing mutations in SUMF1 gene... | ['Arginine', 'Atrophy', 'Cerebral Cortex', 'Child, Preschool', 'Family Health', 'Female', 'Glycine', 'Humans', 'Infant', 'Multiple Sulfatase Deficiency Disease', 'Mutation', 'Oxidoreductases Acting on Sulfur Group Donors', 'Sulfatases', 'Turkey'] | 18,509,892 | [['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['C23.300.070'], ['A08.186.211.200.885.287.500'], ['M01.060.406.448'], ['N01.400.300'], ['D12.125.481'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C10.228.140.163.100.435.825.850.750', 'C16.320.565.189.435.825.850.750', 'C16.320.565.3... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Intrapulmonary lymph node metastasis is common in clinically staged IA adenocarcinoma of the lung. | BACKGROUND: Intrapulmonary lymph nodes (LNs, stations 11-14) are usually omitted in postoperative pathological examination. Some non-small cell lung cancer (NSCLC) patients with intrapulmonary LN metastasis are incorrectly diagnosed as N0 cases. Furthermore, underestimation of intrapulmonary LN involvement in clinicall... | ['Adenocarcinoma of Lung', 'Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Non-Small-Cell Lung', 'Female', 'Follow-Up Studies', 'Humans', 'Lung Neoplasms', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Multimodal Imaging', 'Neoplasm Staging', 'Pneumonectomy'] | 30,468,025 | [['C04.557.470.200.025.022', 'C04.588.894.797.520.055'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reproducibility and stability of neuroelectric source imaging in primary somatosensory cortex. | The present study investigated the test-retest reliability of EEG source localization of somatosensory evoked potentials (SEPs) over an extended time period and tested the accuracy of source reconstruction co-registred with individual brain morphology (MRIs). Seven healthy subjects were stimulated pneumatically at the ... | ['Adult', 'Brain Mapping', 'Electroencephalography', 'Evoked Potentials, Somatosensory', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Models, Neurological', 'Reproducibility of Results', 'Somatosensory Cortex'] | 12,002,348 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E05.599.395.642'], ['E05.318.370.725', 'E05.337.851', 'N05.715.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Specificity and sensitivity of skin test reactions to extracts of Toxocara canis and Ascaris suum. I. Skin tests done on infected guinea pigs. | The specificity and sensitivity of adult and larval somatic antigens, and perienteric fluid of Toxocara canis and Ascaris suum were investigated by using intradermal skin tests in guinea pigs. These animals were infected with low doses (0.01, 0.1 or 1.0 egg/g) of these helminths. Toxocara larval antigen (TL) induced la... | ['Animals', 'Antigens', 'Ascariasis', 'Ascaris', 'Female', 'Guinea Pigs', 'Intradermal Tests', 'Skin Tests', 'Toxocara', 'Toxocariasis'] | 1,155,689 | [['B01.050'], ['D23.050'], ['C01.610.335.508.700.100.070'], ['B01.050.500.500.294.400.500.100.108'], ['B01.050.150.900.649.313.992.550'], ['E01.370.225.812.871.300', 'E05.200.812.871.300', 'E05.478.594.890.300'], ['E01.370.225.812.871', 'E05.200.812.871', 'E05.478.594.890'], ['B01.050.500.500.294.400.500.100.780'], ['C... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies on the quality of breast milk during 23 months of lactation in a rural community of the Ivory Coast. | Milk samples from 33 women from a rural area of the Ivory Coast were analyzed once a month. In two longitudinal studies covering 23 months of breast feeding, analyses of lipid components and protein were performed. The compositions remained virtually constant over 23 months of lactation except for a decrease of protein... | ['Aging', 'Anthropometry', 'Blood Proteins', 'Body Height', 'Body Weight', "Cote d'Ivoire", 'Female', 'Growth', 'Humans', 'Infant', 'Infant Nutritional Physiological Phenomena', 'Infant, Newborn', 'Lactation', 'Lipid Metabolism', 'Milk Proteins', 'Milk, Human', 'Pregnancy', 'Rural Population', 'Time Factors'] | 219,681 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spinal cord compression due to extramedullary haemopoiesis in myelofibrosis. | Extramedullary haemopoiesis resulting in spinal cord compression is rare. This report of extramedullary myeloid metaplasia in a patient with myelofibrosis serves to illustrate the value of magnetic resonance imaging (MRI) in the diagnosis and management of good neurological recovery. | ['Aged', 'Hematopoiesis, Extramedullary', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Primary Myelofibrosis', 'Spinal Cord', 'Spinal Cord Compression'] | 8,027,402 | [['M01.060.116.100'], ['G04.152.825.463', 'G09.188.343.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C15.378.190.636.765'], ['A08.186.854'], ['C10.228.854.761', 'C26.819.678']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Latinos and political advocacy for cancer control in a United States-Mexico border community. | Health policy interventions provide powerful tools for addressing health disparities. The Latino community is one of the fastest growing communities in the United States yet is largely underrepresented in government and advocacy efforts. This study includes 42 Latino adults (M age = 45 years) who participated in focus ... | ['Adult', 'Attitude', 'California', 'Culture', 'Female', 'Focus Groups', 'Health Policy', 'Health Status Disparities', 'Healthcare Disparities', 'Hispanic Americans', 'Humans', 'Male', 'Mexican Americans', 'Mexico', 'Middle Aged', 'Neoplasms', 'Patient Advocacy', 'Politics', 'Qualitative Research', 'Residence Character... | 25,521,784 | [['M01.060.116'], ['F01.100'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['I01.076.201.450', 'I01.880.853.100'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Medial canthopexy: a proven technique. | The medial canthus comprises three limbs and functions to maintain the shape of the eye and to assist in drainage of the lacrimal sac. Repair of the medial canthal tendon is often complicated by canthal drift, extrusion of wires or sutures, and in-fracture of the contralateral orbital bones from pressure by transnasal ... | ['Adolescent', 'Adult', 'Blepharoplasty', 'Child', 'Child, Preschool', 'Eyelid Diseases', 'Female', 'Humans', 'Male', 'Middle Aged', 'Tendons'] | 15,377,898 | [['M01.060.057'], ['M01.060.116'], ['E04.540.104', 'E04.680.275.090'], ['M01.060.406'], ['M01.060.406.448'], ['C11.338'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.880']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Glucose potassium insulin infusions in the treatment of acute stroke patients with mild to moderate hyperglycemia: the Glucose Insulin in Stroke Trial (GIST). | BACKGROUND AND PURPOSE: Hyperglycemia following acute stroke is strongly associated with subsequent mortality and impaired neurological recovery, but it is unknown whether maintenance of euglycemia in the acute phase improves prognosis. Furthermore, the safety of such intervention is not established.METHODS: In an expl... | ['Acute Disease', 'Aged', 'Aged, 80 and over', 'Blood Glucose', 'Blood Pressure', 'Cerebrovascular Disorders', 'Female', 'Glucose', 'Humans', 'Hyperglycemia', 'Hypoglycemic Agents', 'Insulin', 'Male', 'Middle Aged', 'Potassium', 'Treatment Outcome'] | 10,187,881 | [['C23.550.291.125'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C10.228.140.300', 'C14.907.253'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.952'], ['D27.505.696.422'], ['D06.472.699.587.200.500.6... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antiatherogenic effect of isoflavones in ovariectomized apolipoprotein e-deficient mice. | The consumption of isoflavone-containing foods such as soybean and soybean products has been reported to have beneficial effects on the cardiovascular system in postmenopausal women. The present study was carried out to examine the mechanism underlying the beneficial effects of isoflavones in apolipoprotein (apo) E-def... | ['Animals', 'Apolipoproteins E', 'Atherosclerosis', 'Female', 'Isoflavones', 'Mice', 'Ovariectomy'] | 17,902,622 | [['B01.050'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['C14.907.137.126.307'], ['D03.383.663.283.266.450.400', 'D03.633.100.150.266.450.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['E04.270.282.685', 'E04.950.165.685', 'E04.950.300.680']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reducing perinatal mortality in Vila Central Hospital, Vanuatu. | This paper provides accurate figures and detailed analysis of the causes of perinatal mortality in the main referral hospital in Vanuatu in 1992, and discusses possible improvements in management. The perinatal mortality rate for the Vila Central Hospital area was 30.4 per 1000 births (with a stillbirth rate of 14 per ... | ['Asphyxia Neonatorum', 'Cause of Death', 'Family Planning Services', 'Female', 'Humans', 'Infant Mortality', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Perinatal Care', 'Pregnancy', 'Prospective Studies', 'Vanuatu'] | 7,668,056 | [['C16.614.092'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['N02.421.143.401', 'N02.421.800.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550.475', 'N01.224.935.698.489', 'N06.850.505.400.975.550.475', 'N06.850.520.308.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Assessment of laboratory and biosafety practices associated with bacterial culture in veterinary clinics. | OBJECTIVE: To investigate bacterial culture practices in veterinary clinics, with an emphasis on laboratory biosafety and on quality of laboratory practices.DESIGN: Survey-based prospective study.SAMPLE POPULATION: 166 veterinarians.PROCEDURES: Veterinarians were recruited through the Veterinary Information Network (an... | ['Animals', 'Bacteriological Techniques', 'Clinical Laboratory Techniques', 'Colony Count, Microbial', 'Drug Resistance, Bacterial', 'Hospitals, Animal', 'Humans', 'Microbial Sensitivity Tests', 'Prospective Studies', 'Quality Control', 'Surveys and Questionnaires'] | 19,210,256 | [['B01.050'], ['E01.370.225.875.150', 'E05.200.875.150'], ['E01.370.225', 'E05.200'], ['E01.370.225.875.220', 'E05.200.875.220'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['N02.278.421.280', 'N06.230.150.360.250.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.8... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Quality of life in newly diagnosed cancer patients. | The aim of this study was to examine which domains of quality of life are most strongly affected in patients with newly diagnosed cancer, and to examine if quality of life was related to gender, age, educational level, cohabitation, time since diagnosis, treatment or type of cancer in these patients. Ferrans and Powers... | ['Activities of Daily Living', 'Adaptation, Psychological', 'Adult', 'Aged', 'Analysis of Variance', 'Family', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Norway', 'Quality of Life', 'Socioeconomic Factors'] | 10,197,951 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04'], ['Z01.542.81... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
High-resolution crystal structures of Desulfovibrio vulgaris (Hildenborough) nigerythrin: facile, redox-dependent iron movement, domain interface variability, and peroxidase activity in the rubrerythrins. | High-resolution crystal structures of Desulfovibrio vulgaris nigerythrin (DvNgr), a member of the rubrerythrin (Rbr) family, demonstrate an approximately 2-A movement of one iron (Fe1) of the diiron site from a carboxylate to a histidine ligand upon conversion of the mixed-valent ([Fe2(II),Fe1(III)]) to diferrous state... | ['Bacterial Proteins', 'Crystallography, X-Ray', 'Desulfovibrio vulgaris', 'Electron Transport', 'Ferredoxins', 'Hemerythrin', 'Iron', 'Oxidation-Reduction', 'Peroxidase', 'Rubredoxins'] | 15,895,271 | [['D12.776.097'], ['E05.196.309.742.225'], ['B03.440.425.410.350.875', 'B03.660.125.144.500.875.875', 'B03.900.350.875'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D12.776.097.350', 'D12.776.157.427.374.375.275', 'D12.776.556.579.374.375.275', 'D12.776.765.319'], ['D12.776.157.427.374.187', 'D12.776.556.579.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Substance abuse by young adult chronic patients. | Of 41 chronic psychiatric patients between the ages of 19 to 39 seen at a community mental health center, 44 percent were current substance abusers, 29 percent had a history of substance abuse, and only 27 percent had little or no substance abuse history. The three subgroups were similar in diagnosis, gender, and age a... | ['Adult', 'Chronic Disease', 'Female', 'Hospitalization', 'Hospitals, Psychiatric', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Psychotic Disorders', 'Substance-Related Disorders'] | 3,596,487 | [['M01.060.116'], ['C23.550.291.500'], ['E02.760.400', 'N02.421.585.400'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['M01.060.116.630'], ['F03.700.675'], ['C25.775', 'F03.900']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Loneliness in veterans with AIDS and its relationship to the development of infections. | The purposes of this study were to examine loneliness in men with AIDS over a 6-month period and relate the extent of loneliness to the development of infections. Psychoneuroimmunology theory suggests that emotional distress alters immune response. It was believed that loneliness would increase vulnerability to infecti... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Humans', 'Infections', 'Loneliness', 'Male', 'Middle Aged', 'Psychoneuroimmunology', 'Risk Factors', 'Social Support'] | 2,241,247 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01'], ['F01.470.713', 'I01.880.853.748.435'], ['M01.060.116.630'], ['F04.096.795.65... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Evaluation of pre-existing antibody presence as a risk factor for posttreatment anti-drug antibody induction: analysis of human clinical study data for multiple biotherapeutics. | Biotherapeutic-reactive antibodies in treatment-na?ve subjects (i.e., pre-existing antibodies) have been commonly detected during clinical immunogenicity assessments; however information on pre-existing antibody prevalence, physiological effects, and impact on posttreatment anti-drug antibody (ADA) induction remains li... | ['Antibodies, Monoclonal', 'Biological Factors', 'Biological Therapy', 'Clinical Trials as Topic', 'Humans', 'Risk Factors', 'Treatment Outcome'] | 23,761,225 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23'], ['E02.095'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.70... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Outbreak of Salmonella enterica serotype Muenster infections associated with goat's cheese, France, March 2008. | Salmonella enterica serotype Muenster (hereafter referred to as S. Muenster) is rare in France and in Europe. In France, a nationwide outbreak of gastrointestinal illness due to S. Muenster occurred during March and April 2008. Twenty-five laboratory-confirmed cases of S. Muenster were documented by telephone using a t... | ['Adult', 'Animals', 'Animals, Domestic', 'Cheese', 'Child', 'Disease Outbreaks', 'Electrophoresis, Gel, Pulsed-Field', 'Female', 'Food Contamination', 'France', 'Goats', 'Humans', 'Male', 'Middle Aged', 'Salmonella Food Poisoning', 'Salmonella enterica', 'Serotyping', 'Surveys and Questionnaires'] | 19,660,242 | [['M01.060.116'], ['B01.050'], ['B01.050.050.116'], ['G07.203.200.500.444', 'G07.203.300.350.300.444', 'J02.350.500.444', 'J02.500.350.300.444'], ['M01.060.406'], ['N06.850.290'], ['E05.196.401.220', 'E05.301.300.220'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['Z01.542.286'], ['B01.05... | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Non-heparin hemodialysis with oral administration of newly developed antiplatelet agent. | Non-heparin hemodialysis (HD) was successfully done in anuric dogs with the oral administration of a newly developed antiplatelet agent, 4-cyano-5,5-bis(4-methoxyphenyl)-4-pentenoic acid, (E5510, Eisai Pharmaceutical Co., Japan). In the current study, the antithrombotic effect of E5510 during HD was investigated. Eleve... | ['Administration, Oral', 'Animals', 'Dogs', 'Fatty Acids, Monounsaturated', 'Heparin', 'Kidney Failure, Chronic', 'Kidneys, Artificial', 'Platelet Aggregation Inhibitors', 'Renal Dialysis'] | 2,252,660 | [['E02.319.267.100'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['D10.251.355.325'], ['D09.698.373.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E07.858.082.585'], ['D27.505.954.502.780'], ['E02.870.300', 'E02.912.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Square biphasic pulse deep brain stimulation for essential tremor: The BiP tremor study. | BACKGROUND: Conventional deep brain stimulation (DBS) utilizes regular, high frequency pulses to treat medication-refractory symptoms in essential tremor (ET). Modifications of DBS pulse shape to achieve improved effectiveness is a promising approach.OBJECTIVES: The current study assessed the safety, tolerability and e... | ['Aged', 'Aged, 80 and over', 'Deep Brain Stimulation', 'Essential Tremor', 'Feasibility Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Pilot Projects', 'Ventral Thalamic Nuclei'] | 29,102,253 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.331.300', 'E04.190'], ['C10.228.662.350'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Management of pseudo Class III malocclusion--synergistic approach with fixed and functional appliance. | Class III malocclusion has been divided into two subtypes: skeletal and pseudo-Class III. A pseudo Class III malocclusion should be treated as early as possible to reduce the functional shift of the mandible and increase maxillary arch length. A case of pseudo-Class III malocclusion was presented here. A 11-year-old bo... | ['Cephalometry', 'Child', 'Humans', 'Male', 'Malocclusion, Angle Class III', 'Orthodontic Appliances', 'Orthodontic Appliances, Functional', 'Orthodontics, Corrective'] | 23,941,029 | [['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.793.494.650'], ['E06.658.453'], ['E06.658.453.560'], ['E06.658.578']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
LHCII Populations in Different Quenching States Are Present in the Thylakoid Membranes in a Ratio that Depends on the Light Conditions. | LHCII is the major antenna complex of plants and algae, where it is involved in light harvesting and photoprotection. Its properties have been extensively studied in vitro, after isolation of the pigment-protein complex from the membranes, but are these properties representative for LHCII in the thylakoid membrane? In ... | ['Chlamydomonas reinhardtii', 'Light', 'Light-Harvesting Protein Complexes', 'Photosynthesis', 'Spectrometry, Fluorescence', 'Thylakoids', 'Vitamins'] | 26,266,614 | [['B01.650.940.150.385.650'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D05.500.562.488.490', 'D08.811.600.710.490', 'D12.776.543.930.500.490', 'D12.776.765.199.750.750.490'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.56... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Oxidative damage mediated iNOS and UCP-2 upregulation in rat brain after sub-acute cyanide exposure: dose and time-dependent effects. | Cyanide-induced chemical hypoxia is responsible for pronounced oxidative damage in the central nervous system. The disruption of mitochondrial oxidative metabolism has been associated with upregulation of uncoupling proteins (UCPs). The present study addresses the dose- and time-dependent effect of sub-acute cyanide ex... | ['Animals', 'Brain', 'DNA Damage', 'Dose-Response Relationship, Drug', 'Female', 'Lethal Dose 50', 'Nitric Oxide Synthase Type II', 'Oxidative Stress', 'Potassium Cyanide', 'Rats', 'Rats, Wistar', 'Superoxide Dismutase', 'Time Factors', 'Uncoupling Protein 2', 'Up-Regulation'] | 29,609,494 | [['B01.050'], ['A08.186.211'], ['G05.200'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['D08.811.682.664.500.772.500', 'D12.776.157.687.575', 'D12.776.660.720.575'], ['G03.673', 'G07.775.750'], ['D01.625.400.100.750', 'D01.745.635'], ['B01.050.1... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dumped munitions: New insights into the metabolization of 2,4,6-trinitrotoluene in Baltic flatfish. | Livers from dab (Limanda limanda), plaice (Pleuronectes platessa) and flounder (Platichthys flesus) sampled from the Baltic Sea were used to determine the interaction of flatfish CYP1A enzymes with 2,4,6-trinitrotoluene (TNT) in vitro. Competitive inhibition of 7-ethoxyresorufin-O-deethylase (EROD) and 7-methoxyresoruf... | ['Animals', 'Cytochrome P-450 CYP1A1', 'Flounder', 'Liver', 'Trinitrotoluene', 'Water Pollutants, Chemical'] | 32,907,729 | [['B01.050'], ['D08.244.453.005.332', 'D08.244.453.100.500', 'D08.811.682.690.708.170.010.277', 'D08.811.682.690.708.170.020.500', 'D12.776.422.220.453.010.332', 'D12.776.422.220.453.100.500'], ['B01.050.150.900.493.418.438'], ['A03.620'], ['D02.455.426.559.389.832.868'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrical stimulation of the isolated rat intestine in the presence of nutrient stimulus enhances glucagon-like peptide-1 release. | The release of small intestinal hormones by constituents of ingested food, such as fatty acids, is integral to post-prandial responses that reduce food intake. Recent evidence suggests that small intestinal electrical stimulation reduces food intake, although the mechanism of action is debated. To test the hypothesis t... | ['Animals', 'Electric Stimulation', 'Food', 'Gastrointestinal Motility', 'Glucagon-Like Peptide 1', 'Ileum', 'In Vitro Techniques', 'Neural Pathways', 'Rats', 'Rats, Sprague-Dawley'] | 20,664,162 | [['B01.050'], ['E05.723.402'], ['G07.203.300', 'J02.500'], ['G10.261.360'], ['D06.472.317.680.500.500'], ['A03.556.124.684.249', 'A03.556.249.124'], ['E05.481'], ['A08.612'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Characteristics of human fetal spinal cord grafts in the adult rat spinal cord: influences of lesion and grafting conditions. | The present study evaluated the growth potential and differentiation of human fetal spinal cord (FSC) tissue in the injured adult rat spinal cord under different lesion and grafting conditions. Donor tissue at 6-9 weeks of gestational age was obtained through elective abortions and transplanted either immediately into ... | ['Animals', 'Embryo, Mammalian', 'Fetal Tissue Transplantation', 'Fetus', 'Graft Survival', 'Humans', 'Neurons', 'Rats', 'Spinal Cord', 'Spinal Cord Injuries', 'Time Factors', 'Transplantation, Heterologous'] | 9,417,830 | [['B01.050'], ['A16.254'], ['E02.095.147.725.300', 'E04.936.580.300'], ['A16.378'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.675', 'A11.671'], ['B01.050.150.900.649.313.992.635.505.700'], ['A08.186.854'], ['C10.228.854.763', 'C10.900.850', 'C26.819'], ['G01.910.857'], ['E04.936.764']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Assessment of the physical development in children with short bowel syndrome based on selected anthropometric parameters]. | INTRODUCTION: Short bowel syndrome (SBS) results from partial surgical resection of small bowel and requires parenteral nutrition. Aim of the study was to assess physical development and nutrition status of children with SBS.MATERIAL AND METHODS: The study sample included 176 patients (56 girls and 120 boys) aged from ... | ['Anthropometry', 'Child', 'Child, Preschool', 'Comorbidity', 'Developmental Disabilities', 'Energy Intake', 'Female', 'Humans', 'Male', 'Nutritional Status', 'Poland', 'Sex Distribution', 'Sex Factors', 'Short Bowel Syndrome'] | 21,447,270 | [['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['M01.060.406'], ['M01.060.406.448'], ['N05.715.350.225', 'N06.850.490.687'], ['F03.625.421'], ['G07.203.650.240.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.650.650', 'N01.224.425.525'], ['Z01.542.248.679'], ['I01.240.800', 'N01.224.803', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
New hydrazones with pyrazolone structure: synthesis, characterization and biological evaluation. | AIM: To design new hydrazones with pyrazolone structure with improved biological properties.MATERIAL AND METHODS: New hydrazones of antipyrine have been prepared by reaction of 4-aminophenazone (4-aminoantipyrine) with chloracetylchoride and hydrazine hydrate and then condensation with various aromatic aldehydes.RESULT... | ['Ampyrone', 'Anti-Bacterial Agents', 'Anti-Inflammatory Agents, Non-Steroidal', 'Antifungal Agents', 'Antioxidants', 'Chromatography, Thin Layer', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Hydrazones', 'Microbial Sensitivity Tests', 'Pyrazolones'] | 24,340,543 | [['D03.383.129.539.850.077.025'], ['D27.505.954.122.085'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D27.505.954.122.136'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E05.196.181.400.537'], ['B03.440'], ['B03.510'], ['D02.442.288'], ['E01.370.225.875.595'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An engineering approach towards a more discrete and efficient urinary drainage system. | Modern urinary catheter-to-leg-bag systems suffer from a number of shortcomings. Drainage tubing of current urinary leg bags is perceived as unnecessarily bulky compared to the indwelling catheters to which it is connected, and catheter designs are prone to the formation of biofilms, leading ultimately to encrustation ... | ['Computer-Aided Design', 'Consumer Behavior', 'Engineering', 'Equipment Design', 'Urinary Catheters'] | 30,044,175 | [['L01.224.108.150', 'L01.296.110.150'], ['F01.145.236'], ['J01.293'], ['E05.320'], ['E07.132.625']] | ['Information Science [L]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Peritoneal ultrafiltration after chronic exposure to dialysis fluid. | Eleven rats were given twice-daily intraperitoneal injections of 20 mL of dialysis fluid containing 4.5% glucose for 6 weeks. The peritoneal ultrafiltration capacity of this group was compared with that of a control group of 10 rats that had received no injections by measuring the volume and glucose concentration of th... | ['Animals', 'Dialysis Solutions', 'Glucose', 'Male', 'Peritoneum', 'Rats', 'Rats, Inbred Strains', 'Time Factors', 'Ultrafiltration'] | 1,543,781 | [['B01.050'], ['D26.776.708.322', 'D27.505.954.578.483', 'D27.720.752.483'], ['D09.947.875.359.448'], ['A01.923.047.025.600', 'A10.615.789.596'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G01.910.857'], ['E04.292.975', 'E05.196.454.807', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serotonin binds to purified neuronal nitric oxide synthase: a possible explanation for ROS production induced by 5HT in the presence of nNOS. | Serotonin (5HT) was shown to induce in vitro the production of ROS in the presence of neuronal nitric oxide synthase (nNOS) in addition to the basal NO(+) formation. With the aim of understanding this mechanism, this study investigated the potential binding of 5HT to nNOS. By using [(3)H]5HT, it is reported here that 5... | ['Animals', 'Cattle', 'Cytochromes c', 'Electrophoresis, Polyacrylamide Gel', 'Ferricyanides', 'NADP', 'Nitric Oxide Synthase Type I', 'Oxidation-Reduction', 'Oxyhemoglobins', 'Protein Binding', 'Rats', 'Reactive Oxygen Species', 'Serotonin'] | 19,191,108 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D08.244.286.100', 'D12.776.422.220.286.100'], ['E05.196.401.402', 'E05.301.300.319'], ['D01.248.497.158.291.350', 'D01.490.100.300', 'D01.625.400.100.325'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D13.695.827.068.749'], ['D08.811.68... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thymic hormone-containing cells. VII. Adrenals and gonads control the in vivo secretion of thymulin and its plasmatic inhibitor. | The influence of adrenals and gonads on the intrathymic production and the circulating level of thymulin was evaluated in young adult mice. Adrenalectomy (Adx) and gonadectomy (Cx) induce a temporary decrease of thymulin serum level. One simultaneously notes, as a compensatory phenomenon, an increase in the thymic cont... | ['Adrenalectomy', 'Animals', 'Castration', 'Epithelial Cells', 'Epithelium', 'Female', 'Histocompatibility Antigens Class II', 'Kinetics', 'Lipoproteins, LDL', 'Male', 'Mice', 'Molecular Weight', 'Rosette Formation', 'Thymic Factor, Circulating', 'Thymus Gland', 'Thymus Hormones'] | 3,456,002 | [['E04.270.115'], ['B01.050'], ['E04.270.282', 'E04.950.165'], ['A11.436'], ['A10.272'], ['D12.776.395.550.509', 'D12.776.543.550.440', 'D23.050.301.500.400', 'D23.050.705.552.410'], ['G01.374.661', 'G02.111.490'], ['D10.532.515', 'D12.776.521.550'], ['B01.050.150.900.649.313.992.635.505.500'], ['G02.494'], ['E01.370.2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prostaglandin E2-induced ripening of the human cervix involves changes in proteoglycan metabolism. | OBJECTIVE: To elucidate how prostaglandin E2 (PGE2) induces cervical ripening.METHODS: Cervical biopsies were obtained immediately postpartum from women successfully treated with PGE2 gel intracervically. Six specimens were incubated with [35S]sulfate and five were used to characterize the nonlabeled proteoglycan compo... | ['Adult', 'Cervix Uteri', 'Collagen', 'Dinoprostone', 'Female', 'Humans', 'In Vitro Techniques', 'Labor Stage, First', 'Labor, Induced', 'Pregnancy', 'Proteoglycans'] | 8,233,252 | [['M01.060.116'], ['A05.360.319.679.256'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['G08.686.784.769.326.500.080'], ['E04.520.252.968'], ['G08.686.784.769'], ['D09.698.735', 'D12.776.395.650... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Treatment of sleep apnoea using a mandibular advancement splint--an open prospective study. | Obstructive sleep apnoea (OSA) may cause considerable disturbances, including the development of health problems. This study was performed in order to evaluate the results of treating OAS with a mandibular advancement splint (MAS), and to evaluate the effects of this treatment. This was a prospective open longitudinal ... | ['Humans', 'Mandibular Advancement', 'Orthodontic Appliances', 'Prospective Studies', 'Sleep Apnea, Obstructive', 'Snoring', 'Treatment Outcome'] | 22,949,599 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.545.500', 'E06.645.500', 'E06.658.280'], ['E06.658.453'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C08.618.085.852.850', 'C10.886.425.800.750.850'], ['C23.888.852.779.850'], ['E01.789.800', 'N04.761.559.590.800',... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Population genetic structure of critically endangered salamander (Hynobius amjiensis) in China: recommendations for conservation. | Amji's salamander (Hynobius amjiensis) is a critically endangered species (IUCN Red List), which is endemic to mainland China. In the present study, five haplotypes were genotyped for the mtDNA cyt b gene in 45 specimens from three populations. Relatively low levels of haplotype diversity (h = 0.524) and nucleotide div... | ['Animals', 'China', 'Conservation of Natural Resources', 'Endangered Species', 'Gene Flow', 'Genetic Variation', 'Genetics, Population', 'Phylogeny', 'Phylogeography', 'Sequence Analysis, DNA', 'Urodela'] | 27,323,156 | [['B01.050'], ['Z01.252.474.164'], ['J01.256', 'N06.230.080'], ['B01.050.050.565', 'G16.500.275.157.049.250', 'N06.230.080.200', 'N06.230.124.049.250'], ['G05.330.159'], ['G05.365'], ['H01.158.273.343.335'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['H01.158.273.343.335.500', 'H01.277.500.589'], ['E05.393.760.700'], ... | ['Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Control of schistosomiasis in the new Rahad Irrigation Scheme of Central Sudan. | As the new Rahad Irrigation Scheme in Central Sudan began its first agricultural season in 1978, the Blue Nile Health Project was being developed to prevent schistosomiasis and other water-associated diseases in the Rahad and Gezira-Managil schemes. Taken as an indication of overall transmission in the Rahad scheme, th... | ['Agriculture', 'Child', 'Communicable Disease Control', 'Humans', 'Molluscacides', 'Schistosomiasis', 'Schistosomicides', 'Snails', 'Sudan', 'Toilet Facilities', 'Water Supply'] | 4,032,520 | [['J01.040'], ['M01.060.406'], ['N06.850.780.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.031.700.596', 'D27.888.723.596'], ['C01.610.335.865.859', 'C01.920.922'], ['D27.505.954.122.250.075.100.750'], ['B01.050.500.644.400.750'], ['Z01.058.290.120.760'], ['J03.962', 'N06.850.780.200.800.800.795', '... | ['Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Binding kinetics of influenza viruses to sialic acid-containing carbohydrates. | To elucidate the molecular mechanisms of transmission of influenza viruses between different host species, such as human and birds, binding properties of sialic acid-containing carbohydrates that are recognized by human and/or avian influenza viruses were characterized by the surface plasmon resonance (SPR) method. Dif... | ['Carbohydrates', 'G(M3) Ganglioside', 'Humans', 'Influenza, Human', 'Kinetics', 'Ligands', 'Lipid Bilayers', 'Models, Biological', 'Models, Chemical', 'N-Acetylneuraminic Acid', 'Orthomyxoviridae', 'Surface Plasmon Resonance', 'Time Factors'] | 17,624,609 | [['D09'], ['D09.400.410.420.025.475.510', 'D10.390.470.025.475.510', 'D10.570.877.360.025.475.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['G01.374.661', 'G02.111.490'], ['D27.720.470.480'], ['D10.570.510', 'J01.637.087.500.510'], ['E05.599.395'], ['E05... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Adaptation of a high-voltage electron microscope for routine biological dark-field imaging. | Relative merits of different objective aperture geometries for generating dark-field images in a high-voltage electron microscope (an AEI EM7) are considered. Using metal-bar beam stops in the objective lens diffraction plane, with large (500 micron diameter) limiting apertures, effective resolution in the 2-4 nm range... | ['Animals', 'Brain', 'Microscopy, Electron', 'Rats', 'Staining and Labeling', 'T-Phages'] | 6,193,625 | [['B01.050'], ['A08.186.211'], ['E01.370.350.515.402', 'E05.595.402'], ['B01.050.150.900.649.313.992.635.505.700'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.600.670'], ['B04.123.205.891']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dual-FRET imaging of IP3 | In most species, fertilization induces Ca2+ transients in the egg. In mammals, the Ca2+ rises are triggered by phospholipase Cæ (PLCæ) released from the sperm; IP3 generated by PLCæ induces Ca2+ release from the intracellular Ca2+ store through IP3 receptor, termed IP3-induced Ca2+ release. Here, we developed new fluor... | ['Animals', 'Bacterial Proteins', 'Calcium', 'Calcium Signaling', 'Cations, Divalent', 'Female', 'Fertilization', 'Fluorescence Resonance Energy Transfer', 'Fluorescent Dyes', 'Genes, Reporter', 'HeLa Cells', 'Humans', 'Inositol 1,4,5-Trisphosphate', 'Intravital Microscopy', 'Luminescent Proteins', 'Male', 'Mice', 'Mic... | 30,886,280 | [['B01.050'], ['D12.776.097'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D01.248.497.300.333'], ['G08.686.784.277'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['G05.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Orientation of Listing's plane during static tilt in young and older human subjects. | Three-dimensional eye positions, when expressed as rotation vectors, are constrained to lie in a head-fixed Listing's plane. The offset and orientation of Listing's plane changes when the head is tilted. To assess the influence of age on this phenomenon, young (less than 30 years old) and older (>65 years old) human su... | ['Adaptation, Physiological', 'Adult', 'Aged', 'Aging', 'Eye Movements', 'Female', 'Gravitation', 'Head Movements', 'Humans', 'Male', 'Orientation', 'Otolithic Membrane', 'Posture', 'Psychomotor Performance', 'Reflex, Vestibulo-Ocular', 'Rotation'] | 12,505,606 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['G11.427.410.140', 'G14.350'], ['G01.060.350'], ['G11.427.410.478'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.058.577', 'F02.830.606'], ['A09.246.300.909.625.125.680'], ['G11.427.695'], ['F02.808', 'G11.427.700', 'G11.561... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Zinc oxide nanorods modified indium tin oxide surface for amperometric urea biosensor. | ZnO nanorods (ZnONR) grown onto indium-tin-oxide (ITO) coated glass surface using zinc nitrate hexahydrate/hexamethylenetetramine (HMT) in aqueous phase has been utilized for urea biosensor. Urease (Urs) was immobilized onto ZnONR/ITO at physiological pH via electrostatic interactions between Urs and ZnO to fabricate U... | ['Biosensing Techniques', 'Hydrogen-Ion Concentration', 'Indium', 'Limit of Detection', 'Microscopy, Electron, Scanning', 'Nanotubes', 'Urea', 'X-Ray Diffraction', 'Zinc Oxide'] | 22,103,068 | [['E05.601.043'], ['G02.300'], ['D01.268.556.381', 'D01.552.544.381'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['J01.637.512.850'], ['D02.065.950'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965'], ['D01.650.550.975'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Implications of quantal motor action in biological systems. | We demonstrate in this paper that quantal behavior is a central feature of biological motile and contractile systems. Step-like behavior has been demonstrated in the interaction between single molecules and filaments both in the kinesin-microtubule system and in the myosin-actin filament system. We show here that the s... | ['Actins', 'Animals', 'Humans', 'Muscle Contraction', 'Muscle, Skeletal', 'Myosins'] | 9,889,848 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494'], ['A02.633.567', 'A10.690.552.500'], ['D05.750.078.730.475', 'D08.811.277.040.025.193.750', 'D12.776.210.500.600', 'D12.776.220.525.475']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
One hundred private psychiatric patients. | One hundred psychiatric patients seen for the first time on a private basis received a research interview that allowed a study of demographic and clinical characteristics. Eighty-five had a discrete psychiatric disorder and fifty were suffering affective disorders. Most sought psychiatric attention because of a situati... | ['Adult', 'Emergencies', 'Female', 'Hospitalization', 'Humans', 'Interview, Psychological', 'Male', 'Mental Disorders', 'Middle Aged', 'Mood Disorders', 'Office Visits', 'Patients', 'Private Practice', 'Psychiatry', 'Sex Distribution'] | 17,894,072 | [['M01.060.116'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['F03'], ['M01.060.116.630'], ['F03.600'], ['N04.452.758.635'], ['M01.643'], ['N04.452.758.745'], ['F04.096.544', 'H02.403.690'], ['I01.240.800',... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
[Haptoglobin administration for hemolysis with autotransfusion of blood ultrafiltered after cardiopulmonary bypass]. | Ultrafiltration is well known as a useful method of hemoconcentration of the blood after cardiopulmonary bypass, but free hemoglobin increase is a problem in autotransfusion. The purpose of this study was to investigate the effect of haptoglobin administration for hemolysis with autotransfused blood ultrafiltered after... | ['Adult', 'Blood Transfusion, Autologous', 'Cardiopulmonary Bypass', 'Female', 'Haptoglobins', 'Hemolysis', 'Humans', 'Male', 'Middle Aged', 'Ultrafiltration'] | 2,020,144 | [['M01.060.116'], ['E02.095.135.164'], ['E04.292.413'], ['D12.776.124.050.300', 'D12.776.124.790.106.394', 'D12.776.377.715.085.394', 'D12.776.395.560.373'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.292.975', 'E05.196.454.807', 'G01.280.807', 'G02.263.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sildenafil-induced reversible impairment of rod and cone phototransduction in monkeys. | PURPOSE: To investigate functional alteration of the retina induced by sildenafil in monkeys.METHODS: Sildenafil was administered intravenously to cynomolgus monkeys at dose levels of 0, 1, 3, and 10 mg/kg, and standard full-field electroretinograms (ERGs) were recorded. The rod and cone a-waves in response to high-int... | ['Animals', 'Electroretinography', 'Injections, Intravenous', 'Macaca fascicularis', 'Ophthalmoscopy', 'Phosphodiesterase 5 Inhibitors', 'Photic Stimulation', 'Photoreceptor Cells, Vertebrate', 'Piperazines', 'Purines', 'Sildenafil Citrate', 'Sulfonamides', 'Vision Disorders', 'Vision, Ocular'] | 25,574,056 | [['B01.050'], ['E01.370.380.225', 'E01.370.405.270'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'], ['E01.370.380.560'], ['D27.505.519.389.735.500'], ['E05.723.729'], ['A08.675.650.850.625.670', 'A08.675.650.915.937.670', 'A08.800.950.937.670', 'A09.371.729.831... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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