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Integrated Management of Childhood Illness (IMCI) initiative was taken to prevent morbidity and moality from 1) diarrhoea 2) ARI (Acute Respiratory Tract Infections) 3) Malaria 4) Measles 5) Malnutrition. Ref: Park's Textbook of Preventive and Social Medicine By K. Park, 19th Edition, Page 372; Textbook of Paediatric N...
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Gall stones are the most common cause, alcohol being IInd most common. Ultrasound is often the first imaging investigation but CT is the best imaging investigation. Serum amylase is the most widely used laboratory test because of its simplicity. It lacks the specificity to pancreas and may be raised in a multitude of c...
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Preterm labor is defined as one where the labor stas before 37th completed week, counting from the first day of the last menstrual period Lower limit of gestation is - 20 weeks in developed countries 28 weeks in developing countries Ref: Dutta Obs 9e pg 294.
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Ans. is c, i.e Sulfadoxine - pyrimethamineRef. Williams 24/e, pg1257, high risk pregnancy fernando arias 4/e, pg 313Intermittent Preventive Therapy is a newer modification of prophylaxis. In chemo prophylaxis, the drugs have to be given daily or weekly, wherein in IPT the pregnant females are treated for malaria presum...
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The graft mounts an immune response against the antigens of the host is called graft-versus-host reaction. The immunocompetent T cells of the graft are responsible for this reaction. The recipient possesses transplantation antigens that are absent in the graft. Reference:athanarayan & paniker's 9th edition, pg no: 186 ...
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Ans. is 'd' i.e., Compulsive acts that relieve the tension Schneider's first rank symptomsHallucinations Audible thoughts, voices commenting on one's action, voices heard arguing two or more hallucinatory voices discussing the subject in third person (third person hallucination).Thought attention phenomena Thought inse...
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Ans. C: Hyperglycemia Dumping syndrome is a relatively rare disorder in which the stomach contents are delivered too quickly to the small intestine. It occurs as a physiological reaction to the consumption of too much simple or refined sugar in some persons, when simple sugar exits the stomach too rapidly it attracts f...
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Ans. is 'a' Digoxin is helpful (Ref. to May 2001, Harrison 17/e, p 1484 & 16/e, p 1411).
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(A) Posterior inferior cerebellar artery > In unilateral infarcts there is always a sharp delineation in the midline because the superior vermian branches do not cross the midline, but have a sagittal course.> This sharp delineation may not be evident until the late phase of infarction.> In the early phase, edema may c...
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Ans. is 'c' i.e., Amphotericin B
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Ans-A Keratinocytes o Blaschko's lines correspond to the pathways followed by keratinocytes migrating from the neural crest during embryogenesis.o The lines follow a V-shape over the spine, an S-shape on the abdomen, inverted U-shape from the breast area to the upper arm and perpendicular down the front and back of the...
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Symptoms dysuria vaginal discharge excessive irritant acute unilateral pain and swelling over labia rectal discomfo labia look swollen and inflamed D.C.DUTTA'S TEXTBOOK OF GYNECOLOGY,Pg no:147,6th edition
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MC symptom: Dull aching pain in the veins at the end of the day, after prolonged standing Duplex ultrasound: Investigation of choice for diagnosis of varicose veins Bisgaard's Regime is Limb elevation + Compression stockings + Massage for varicose ulcers Endothermal Ablation(EVLA and RFA) is gold standard treatment for...
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Ans. is 'b' i.e., Chloride content of blood in drowning Gettler test estimates chloride content of blood from both sides of hea. It is done for drowning. Normally the chloride content is equal in the right and left chambers of the hea (600 mg/100 m1). In fresh water drowning due to hemodilution the chloride content is ...
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Ans. is 'a' i.e., Breast o Tumors metastatic to the hea are much more common than primary tumors. o The most common tumors metastatizing to hea are lung and breast. o Other tumors are malignant melanoma, lymphoma and leukemias.
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Fractures of the mandible (Dig man's classification)Condylar process35% Angle of mandible20%Body of mandible20%Symphysis 15%Alveolar process5%Ramus 3%Coronoid process2%Most common fracture - condylar fracture followed by angle, body & symphysis of the mandible (mnemonic - CABS)(Refer: Mohindra's Fundamentals of Ohopedi...
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Morphologic stage of tooth development: Is determined by the epithelial part of the tooth germ, i.e. Enamel organ.
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Ans: b (Vit E) Ref:Harrison, 16th ed, p. 409Vitamin E deficiency is a cause of spinocerebellar ataxia.Spinocerebellar ataxiaIt is an autosomal dominant condition. It includes spinocerebellar ataxia type 1 to type 22.They are caused by CAG triplet repeat expansions.CAG encodes glutamine and these expandedCAG triplet exp...
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Ans: (b) IsofluraneRef: Stoelting's Pharmacology and Physiology in Anesthetic Practice, 4th editionMAC (MINIMUM ALVEOLAR CONCENTRATION)MAC is the concentration of inhalational agent in alveoli at 1 atm that prevents skeletal muscle movement in response to a supra-maximal painful stimulus (surgical skin incision) in 50%...
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Ans. is 'b' i.e. Adipocere formation All the four can be seen in a dead bom fetus but adipocere formation being rare should be the answer."A dead born child is one which has died in utero and may show signs of rigor mortis, maceration or mummification *"Rarely a child which has remained surrounded in amniotic fluid aft...
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Size of polyp > 5mm Repeat .from All India 09 "Risk factors associated with malignancy are age older than 60 years, coexistence of gallstones, a documented increase in size, and size larger than 10 mm. All patients with symptomatic polyploid lesions of the gallbladder should undergo laparoscopic cholecystectomy. Any pa...
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Infections with Rickettsia rickettsii, Treponema pallidum, and coxsackievirus all can cause a rash on the palms and soles. This patient is most likely infected with R rickettsii. The clinical course is typical for Rocky Mountain spotted fever, which is characterized by fever with abrupt onset and a rash that spreads fr...
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(Ref: KDT 6/e p729) Diagnosis is atypical pneumonia and DOC is erythromycin.
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Islet cell transplantation involves the extraction of islets of Langerhans from organ donors through a complex purification process. These are the cells responsible for the production of insulin. These cells are then injected into the recipient, usually into the poal vein. They then engraft into the parenchyma of the l...
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Congestive hea failure (CHF) is unusual in childhood. When it does present, it is usually as a manifestation of congenital hea disease and is seen in the first year of life. The classic triad of symptoms for pediatric CHF is tachypnea, tachycardia, and hepatomegaly. There may also be a history of poor feeding, sweating...
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Ans. B 2nd branchial archRef: Gray's Anatomy, 41st ed. pg. 449* The stylohyoid ligament is a fibrous cord extending from the tip of the styloid process to the lesser cornu of the hyoid bone. It gives attachment to the highest fibres of the middle pharyngeal constrictor and is intimately related to the lateral wall of t...
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1st image shows ischemic colitis with patchy mucosal edema, subepithelial hemorrhage, and cyanosis. 2nd image shows the classical thumb printing sign. Most impoant precipitating factor - Surgery in an old individual Most common surgery leading to it - Repair of abdominal aoic aneurysm Colonoscopy findings show haemorrh...
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Palate is supplied by greater and lesser palatine aeries of the descending palatine aery (branch of maxillary aery), the ascending palatine aery (branch of facial aery), and the palatine branch of the ascending pharyngeal aery.
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KISHORI SHAKTI YOJANA (KSY): • KSY is rename of ‘Adolescent Girl’s Scheme’ under ICDS (Integrated Child Development Services) • Aim of KSY: – To improve the nutritional and health status of adolescent girls – To promote self-development, awareness of health, hygiene, nutrition, and family life and child care – KSY cove...
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Ans. is 'd' i.e., Granulosa cell tumor o Primary ovarian tumors are further divided into three typesi) Surface epithelial tumorsii) Germ cell tumorsiii) Sex cord stromal tumorsSurface epithelial tumorsGerm cell tumorsSex cord stromal tumorso Serous tumoro Teratomao Thecomao Mucinous tumoro Dysgerminomao Fibromao Endome...
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Causative agents of UTI:Uncomplicated UTIComplicated UTI*E.coli *Klebsiella*Proteus species*Enterobacter*Staphylococcus saprophyticus*Enterococci *Chlamydia , Neisseria *Ureaplasma, Mycoplasma . Adenovirus *E.coli *Klebsiella*Proteus species*Serratia marcescens*Pseudomonas *Enterococci Staphylococci Ref:Harrison's infe...
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Fat containing breast lesions are Lipoma, Galactocele, Hamartoma, Traumatic lipid cyst (fat necrosis), oil cyst.
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Ans. is 'b' i.e., Prolactin deficiency Bromocriptine is used in :- Suppression of lactation in galactorrhea Cyclical mastalgia Induction of ovulation in anovulatory infeility caused by hyperprolactinemia Parkinsonism Acromegaly due to small pitutary tumours Hepatic coma Recently, it has been approved for treatment of t...
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Ans. a. HRCT (Ref: Harrison 19/e p1694, 18/e p2143)HRCT is investigation of choice for diagnosis of bronchiectasis.High Resolution Computed tomography (HRCT)HRCT uses very thin 1-2 mm thin slicesQ.HRCT is used primarily to diagnose:BronchiectasisQInterstitial lung diseaseQ (Fibrosing alveolitis, asbestosis)Bronchiectas...
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linical features of ulcerative colitis : The primary presenting symptom of ulcerative colitis is blood in the stools. Loose stools (or a decrease in stool consistency) for more than six weeks differentiates UC from most infectious diarrhoea. Extensive active UC 1. Chronic diarrhoea almost invariably associated with 2. ...
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Tranexamic acid and EACA are antifibrinolytic drugs which are used as antidotes for the management of fibrinolytic drug poisoning.
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Periventricular leukomalacia are zones of necrosis of white matter in the deep territories of coical and central aeries. They lie lateral and posterolateral to the lateral ventricles, in a position to involve the occipital radiations and the sensorimotor fibers in the corona radiata. Survivors often manifest cerebral h...
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According to the standard laid down by WHO, anaemia in pregnancy is present when the haemoglobin concentration in the peripheral blood is 11 gm/100 ml or less. During pregnancy plasma volume expands (maximum around 32 weeks) resulting in hemoglobin dilution. For this reason, haemoglobin level below 10gm/dl at any time ...
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This glycoprotein is synthesized early in gestation by the fetal yolk sac and later by the fetal gastrointestinal tract and liver. Its concentration increases steadily in both fetal serum and amniotic fluid until 13 weeks, after which, levels rapidly decrease. Conversely, AFP is found in steadily increasing quantities ...
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D i.e. All
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Rapidly spreading infection of external auditory canal, seen in diabetic patient with involvement of bone and presence of granulation tissue point towards malignant otitis externa as the diagnosis. Treatment Includes correction of immunosuppression (when possible), local treatment of the auditory canal, long-term syste...
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Ans. is 'd' i.e., Doxycycline o This question is confusing one.o I think examiner asking about treatment of choice for chlamydia, when treating it with gonorrhea,o Emperical treatment of urethral discharge (urethritis) has two components -Doxycycline or azithromycine for chlamydia.Ceftriaxone or fluoroquinolone for gon...
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Ans. is 'd' i.e., Nucleus gracilis & cuneatusThe nucleus gracilis and cuneatus give rise to the internal arcuate fibres.The fibres cross to the opposite side where they form a paramedian band of fibres, called the medial lemniscus. In the lemniscus, the body is represented with the head posteriorly and the feet anterio...
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In de novo synthesis of purine nucleotides, there are 10 steps. The 4th step (addition of N3) is catalysed by the enzyme Formyl glycinamide ribonucleotide amidotransferase. This enzyme is inhibited by azaserine, an anticancer drug. Reference: Harpers illustrated biochemistry 30th edition
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Hydrocele
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Ans. is 'd' i.e. Ciliary body Wound involving the ciliary body are most prone to develop sympathetic ophthalmitis, thus ciliary region is k/a the dangerous zone of the eye.
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Contusion (Bruises) it is the effusion of blood into tissues, due to rupture of blood vessels and due to blunt violence. Lathi injury is an injury caused by blunt force. In contusion, there is painful swelling and crushing or tearing of the subcutaneous tissue, usually without destruction of the skin.
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Ref: Katzung 11/e p397 *The antidote of ethylene glycol poisoning is ethanol or fomepizole. The kidney toxicity of ethylene glycol occurs 24 to 72 hours post ingestion and is causedby a direct cytotoxic effect of glycolic acid. ... The most significant effect isaccumulation of calcium oxalate crystals in the kidneys wh...
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* Major aim of metabolism (Biotransformation) is to conve lipid-soluble (non-polar) drugs to water soluble (polar) drugs. * In the absence of metabolism, body will not be able to get rid of lipophilic substances, and they will become very long acting. * Biotransformation of drugs may lead to any of the following 1. Ina...
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Ans. is 'c' i.e., CSF ABO antigen can be demenstrated in all body fluids except CSF"_________ Reddy. They are detected in almost all tissues, but not found in - Nerve tissue Epithelium Skin appendages Bone Cailage
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harshmohan textbook of pathology 7 th edition Platelet granules are released by the activated platelets .one of the platelet granules is dense bodies and their release liberates ADP ,ionic calcum ,5_HT,Histamine and epinephrine.VWF is synthesised by endothelial cells
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Ans. (C) Eye examination(Ref: CMDT 2010, 1501)Methotrexate toxicities include:MyelosuppressionNephrotoxicityHepatotoxicityNeurotoxicity (with intrathecal administration and high-dose therapy)PhotosensitivityPulmonary toxicityMultiple drug interactions which may enhance toxicities (avoid aspirin, penicillins, NSAIDs, om...
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Ans. is 'c' i.e., Sigmoid colon o Diverticulosis refers to presence of multiple diverticula,o Diverticula are of two types - (i) Congenital, and (ii) Acquired.Congenital diverticula : (the prototype of which is Meckel's diverticula) are not so common. They contain all the layers of the intestine are thus termed 'true' ...
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Pneumatoceles which is a characterstic feature of Staph aureus pneumonia - can rupture and lead to the formation of Pneumothorax(shown in the given X ray)
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Mifepristone is an analog of progestin acts as an antagonist blocking the effect of natural progesterone. It is used as a medical method of first trimester aboion. It is highly successful when used within It is not indicated in the treatment of post paum hemorrhage. Bleeding and bleeding disorders are a contraindicatio...
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The term multiple endocrine neoplasia (MEN) encompasses several distinct syndromes featuring tumors of endocrine glands, each with its own characteristic pattern. In some cases, the tumors are malignant, in others, benign. Benign or malignant tumors of nonendocrine tissues occur as components of some of these tumor syn...
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Ans. A: Panel discussion In panel discussion there is a chairman/moderator and 4-8 speakers. Each speaker prepares separately, the other speakers hear one another for the time at the session itself. Panel discussions, however, differ from team presentations. Their purpose is different. In a team presentation, the group...
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Congenital diaphragmatic hernia(CDH) occurs when the diaphragm muscle -- the muscle that separates the chest from the abdomen -- fails to close during prenatal development, and the contents from the abdomen (stomach, intestines and/or liver) migrate into the chest through this hole. Reference: GHAI Essential pediatrics...
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Shigellosis is best diagnosed by Stool examination & culture. Option 1 1. Stool is the specimen of choice. Diagnosis of shigellosis is made by isolating Shigella spp. from feces. Fresh feces are inoculated without delay or transpoed in a suitable medium, such as Sachs' buffered glycerol saline. Also, rectal swabs may b...
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Ans. is 'b' i.e., The ileo-appendicular fold of peritoneum.
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Ans. (b) Liver(Ref: Robbins 9th/pg 862; 8th/pg 869)Von Meyenburg ComplexesClusters of dilated bile ducts embedded in a fibrous, sometimes hyalinized, stroma located close to or within portal tracts.These lesions are often referred to as "bile duct hamartomas"They are without clinical significance except in the differen...
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Munro microabscess →   Psoriasis Pautrier microabscess → Mycosis fungoides
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The facial nerve is most commonly damaged in CSOM because it traverses through the middle ear.Ref: Hazarika; 3rd ed; Pg 164
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high frequency discharges are inhibited with little effect on normal low frequency discharges which allow Na+ channels to recover even when inactivation is prolonged. This effect has been noted at therapeutic concentration of phenytoin, while other effects like reduction in Ca2+ influx, inhibition of glutamate and faci...
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Answer is A (Residual volume Normal): Lung disease is typically associated with an Increased Residual volume Taken from Harrison 17th/1588 The hallmark of obstructive Lung Disease is decreased expiratory flow rate such the FEF25_75 is reduced and FEVI is typically reduced out of propoion to the Forced Vital Capacity ('...
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Affinity chromatography is based on the exceptional ability of biologically active substances to bind specifically and reversibly other substances generally called ligands or affinity ligands or simply affinants. Affinity chromatography provide a high degree of protein purification due to the specificity of the binding...
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Local anaesthetic and opioids are bases. Once they reach the fetus they become nonionized (due to highly acidic pH) and can not come back to maternal circulation leading to toxic accumulations in fetus.
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B i.e. Cobalt-60 In brachytherapy the source of radiation is placed very close to the site of action. It can be invasive technique as it needs the implantation of needle into the tumor (interstitial) or in the cavity (intracavitary). It is often used in brain tumors & cervical cancers. It requires trained perssonels. M...
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Treatment of choice for phylloides tumor is excision or subcutaneous mastectomy is done if malignant, total mastectomy is done phylloides tumor also known as cystosarcoma phylloides/ serocystic disease of broide they are simply giant fibroadenoma ref ;(page no;521) 5th edition of SRB&;S Manual of SURGERY
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Ans. A: Copy Circle Copying a circle: 3 years Rides tricycle: 3 years Copies cross: 4 years Copying triangle: 5 years
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most common occular foreign body is iron. And the most common mode is chissel and hammer Refer khurana 6/e p 421
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Ans. is 'd' i.e., Water sanitationControl of cholera (WHO guidelines)o Measures taken to control cholera epidemic are1) Verification of diagnosis: Identification of V. cholera 01 in stools of few patients is sufficient. It is not necessary to culture stools of all cases or contacts.2) Notification: Cholera is notifiabl...
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Fundamental aspects of disaster management include disaster mitigation, disaster preparedness, and disaster response. Ref: Park, 21st Edition, Page 736.
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Ans. is b i.e. To take Warfarin after delivery Friends venous thromboembolism in pregnancy, is one of those topics which we donot study in detail during undergraduation. So, I am giving in brief, all the impoant points you need to remember : Venous thromboembolism in pregnnacy : Venous thromboembolism is the leading ca...
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ANSWER: (A) SrREF: Perez and Brady's Principles and Practice of Radiation Oncology 5th ed Page 1997See APPENDIX-67 below for "ISOTOPES USED IN RADIOTHERAPY"A medical isotope of strontium is Sr-89, which is used for pain relief in certain bone cancers. Strontium 89 is a pure b emitter with half life of 50.6 daysStrontiu...
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.
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T Score and Z score are the measures of bone mineral densityZ score: measures the bone mineral density in terms of standard detion from the mean bone mineral density of age, race, and sex-matched individualsT score: measures the bone mineral density in terms of standard detion from the mean bone mineral density of race...
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Adverse effects of CCBs - Nausea, constipation and bradycardia are more common with Verapamil.  Verapamil can accentuate conduction defect-should be avoided in 2nd & 3rd degree block, in sick sinus syndrome and along with beta-blocker.  Most common side effects of DHPs are palpitation, flushing, hypotension, headache,...
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(C) Cinnarazine# Urinary retention, also known as ischuria, is a lack of ability to urinate. It is a common complication of benign prostatic hyperplasia (BPH), although it can also be caused by nerve dysfunction, constipation, infection, or medications (including anticholinergics, anti- depressants, COX-2 inhibitors, a...
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B i.e. Interstitial Lung disease - Routine chest CT examinations consist of adjacent 8-10 mm sections through the area of interest. Intravenous contrast medium may be injected when the primary purpose of examination is to show the mediastinum or hilar structures. High resolution CT (HRCT) uses very thin 1-2 mm thick.(2...
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In a normal person phonation is produced by vocal cords which vibrate in response of force of air produced by lungs. In oesophageal speech, patient "inhales" air into the oesophagus and then ejects it by the contraction of chest muscles. Pharyngo-oesophageal segment functions for the missing vocal cords and vibrates to...
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The anterior wall is narrow due to approximation of the medial and lateral walls, and because of descent of the roof. The uppermost pa of the anterior wall bears the opening of the canal for the tensor tympani. The middle pa has the opening of the auditory tube. the inferior pa of the wall is formed by a thin plate of ...
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Pepsin is secreted (in an inactive or zymogen form as pepsinogen) by the chief cells of the stomach. Pepsinogen is activated by contact with stomach acid. Although protein digestion usually begins with the actions of hydrochloric acid and pepsin, pancreatic enzymes complete the job as the food passes into the small int...
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When ammonia is present in body in large amount (hyperammonemia), then this alpha-ketoglutarate of TCA combines with one amino group to form glutamate Fuher glutamate combines with the second amino group to form glutamine Glutamine is a safe form of ammonia storage & transpo. Alpha-ketoglutarate is depleted, which affe...
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Ans- D. Obscured Contralateral hemidiaphragm Correct statement- Obscured ipsilateral hemidiaphragm
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Recent recognition that periodontal disease may have its origins in childhood has led dentists to be more aggressive in treatment. Studies confirm a high prevalence of gingival inflammation in children. Reference: McDONALD AND AVERY’S DENTISTRY for the CHILD and ADOLESCENT, 10th ed page no 243
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Ans. (b) Nuclear cataractRef: Parson's 21/e, p. 266Congenital rubella infection can cause congenital nuclear cataract and congenital total cataract.Sometimes it may also cause lamellar (zonular) cataract (Occurs in fetal nucleus. Thus a type of congenital nuclear cataract)
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Answer: c) 74
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Composed of 6 layers. LAYERS OF CEREBRAL COEX: Composed of 6 layers - Layer/Lamina I - "Molecular layer" Contains nerve fibers. Mainly dendrites of pyramidal cells & axons of granular cells. Layer/Lamina II - "External granule cell layer" Contains mainly granule cells. Layer/Lamina III - "External pyramidal cell layer"...
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1. Pyruvate carboxylase2. Phosphoenolpyruvate carboxykinase3. Fructose-1-6-bisphosphatase4. Glucose-6-phosphataseGluconeogenesis involves several enzymes of glycolysis, but it is not a reversal of glycolysis. The irreversible steps in glycolysis are circumvented by four enzymes which are designated as the key enzymes o...
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Activation heat is the heat that muscle produces whenever it contracts. Heat Production in Muscle Resting Heat: The heat given off at rest due to the basal metabolic processes . Initial Heat: The heat produced in excess of resting heat during contraction. It is made up of two subtypes: Activation Heat: The heat that mu...
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Acinetobacters are oppounistic pathogens and are frequently present on normal skin. They are the cause of hospital-associated infections but are not hospital acquired. Ref: Ananthanarayan& Paniker&;s textbook of microbiology, 9th edition. Pg no.398
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Ans. is 'a' i.e., Virulence is due to polysaccharide capsule* Capsular polysaccharide is the principal virulence factor, protects it from phagocytosis. Other virulence factors are toxins (pneumolysin and autolysin).
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(Refer: AK Khurana Comprehensive Ophthalmology, 6th edition, pg no. 136)"Donor corneas are harvested from cadaveric donors within 6 hours after death, sometimes up to 12 hours after death in countries with cold climates".
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Osteoporosis It refers to reduction ofbone mass per unit volume (loss of matrix and defective mineralisation) (Fig. 9.47). Aetiology 1.Involutional 2.Endocrinological 3.Gastrointestinal 4.Haematological 5.Rheumatological 6.Collagen vascular Normal bone Type I (postmenopausal) and Type II (senile) Hypehyroidism Hyperpar...
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Terlipressin causes vasoconstriction by acting on V1a/V1 receptor. (V1b receptor is also called as V3 receptor)
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Halothane Effect of Anaesthesia on Hepatic Blood flow Hepatic blood flow usually decreases during regional and general anaesthesia. Multiple factors are probably responsible including :? - Direct and indirect effect of anaesthetic agent - The type of ventilation employed - Type of surgery being performed All anaestheti...
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Ans. (d) Fertilization takes place in ampulaRef.: D.C. Dutta 8th ed. / 32-36, 7th ed. 121-22Option A-Placenta is formed by trophoblast which 1st appear at blastocyst stage, hence option A is wrong.Option B-Implantation takes place on 6th day.Option C-During initial weeks corpus leuteum surviaval is due to HCG, not due ...
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Fetal cardiac activity can be detected earliest by USG at 5-6-week age of intrauterine life.
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Ans. is 'c' i.e., Potency Median effective dose o The dose that will produce half the maximum (50%) response. o More the ED, is the potency.
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