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Ans. D. All of the aboveExplanationPlasmidThey are extrachromosomal ds circular DNA molecules that exist in free state in the cytoplasm of bacteria, and also found in some yeasts.Plasmids are not essential for life.They can be present singly or in multiple numbers up to 40 plasmids per cell.They are capable of independ...
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There are three serotypes of poliovirus. They are type 1, 2 and 3. Serotype 1 is the most common type, it is the most common serotype causing polio epidemic. Mutated Type 3 is the most common cause of vaccine induced paralysis. Poliovirus belong to enterovirus group. It is a single stranded RNA virus. It has a naked pr...
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Answer is B (Interferon Beta) : Interferon Beta should be considered in patients with Relapsing / Remitting MS (RRMS) and Secondary Progressive MS (SPMS) with superimposed relapses. Interferon Beta reduces the attack rate in M.S. patients and also improves disease severity measures and disease burden. Interferons Inter...
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Ans. is 'a' i.e., Bupivacaine Bupivacaine (Sensoricaine. Marcaine)o Bupivacaine is 2nd most commonly used local anaesthetic (after lidocaine).o Bupivacaine has the highest local tissue irritancy amongst local anaesthetics,o It is the most cardiotoxic local anaesthetic.o Levobupivacaine (The S(-) enantiomer of bupivacai...
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Degenerative joint disease or osteoarthritis is a non-inflammatory disorder of joints characterized by joint deterioration and new bone formation. The new bone formed is called osteophyte. In severe cases, the osteophytes may break-off and lie free within joint space. These fragments are known as "Joint mice or mouse" ...
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.<p>in case of a case control study ,we cannot measure incidence,and can only estimate the relative risk.and it doesnot distinguish between causes and associated factors.and it is also not suited to the evaluation of therapy or prophylaxis of disease.selectin of an appropriate control group may be difficult.</p><p>ref;...
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Ans. (b) Acute viral HepatitisUSG Abdomen shows presence of starry sky pattern of the liver, diagnostic of acute viral hepatitis
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Extracellular matrix (ECM) is a network of interstitial proteins that constitutes a significant propoion of any tissue. ECM serves several key functions: Mechanical suppo Control of cell proliferation Scaffolding for tissue renewal Establishment of tissue microenvironments Components of Extracellular matrix Fibrous str...
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Ans. is 'b' Social phobia Social Phobia is characterized by irrational fear of performing activities in presence of other people or interacting with other, the pt. is afraid of his actions being viewed by others critically resulting in embarrassment.Avoidant Personality Disorder :It is very difficult to distinguish b/w...
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A i.e. Rupture of anterior talo-fibular ligament
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Ans. (c) MaxillaryRef: Dhingra's 4th ed p-195
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“A distinctive variant of hepatocellular carcinoma is the fibrolamellar carcinoma, constituting less than 5% of HCCs. This tumor occurs in young male and female adults (20 to 40 years of age) with equal incidence, has no association with HBV or cirrhosis risk factors, and often has a better prognosis It usually present...
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Roughly 2.5 grams of good quality bleaching powder would be required to disinfect 1,000 liters of water.This will give an approximate dose of 0.7 mg of applied chlorine per litre of water (refer pgno:718 park 23rd edition)
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Ans. All of the above
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A i.e. It is the strongest pa of boneStrongest poion of bone is diaphysis (not metaphysis); Maximum growth occurs in physis (epiphyseal growth plate) followed by metaphysis Q
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Ans. is 'b' i.e.. Vertebrae o Most common site of osteoporosis is vertebrae.Clinical features of osteoporosiso Osteoporosis is an asymptomatic disorder unless complications (predominantly fractures) occur,o Most common symptom of osteoporosis is back pain secondary to vertebral compression fracture.o Dorso-lumbar spine...
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Glucose-6-phosphate is an important compound that joins several metabolic pathways viz. glycolysis, glycogenolysis, glycogenesis, gluconeogenesis and pentose phosphate pathway.
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NaSSA * IMPOANCE Nor adrenergic and specific serotonergic antidepressant * MECHANISM * Alpha 2 adrenergic receptor antagonism=== increase serotonin and NA * 5HT2,3 antagonist============increase sleep and appetite * DRUGS miazapine * USE Elderly with depression * SIDE EFFECTS hyperlipidemia ref. kaplon and sadock, syno...
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Ans. is 'c' is Preganglionic parasympathetic fibres are more lengthy The cell bodies of the post ganglionic parasympathetic neurons are located on or near the body of the viscera and therefore postganglionic neurons are very short.Whereas the cell bodies of the preganglionic parasympathetic neurons are located in the i...
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Ans. is 'a' i.e., Age < 3 years Post operative nausea and vomiting (PONY) following strabismus surgery It can cause post - op wound dehiscence, hematoma, orbital hemorrhage and aspiration. 30 % of all procedures are associated with PONV. Major risk factors are: Age > 3years Duration of anesthesia > 30 mins Personal or ...
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Rarely, an embolus passes through an atrial or ventricular defect and enters the systemic circulation called paradoxical embolism. Pulmonary Embolus can occlude the main pulmonary artery, lodge at the bifurcation of the right and left pulmonary arteries called saddle embolus. Robin’s Textbook of pathology 10th ed Page ...
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Testicular lymphoma is the most common testicular tumor in patients older than 60 years.
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ZIKA VIRUS Flavivirus vector = Aedesegypt Specimen 1 serum 2 wholeblood 3 urine =Best 4 CSF not recommended symptoms similar to chicken gunya FDA = EUA =Emergency use authorization TRIOPLEX r PCR Zika MAC eLISA ref: ANANTHANARYANA MICROBIOLOGY
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Since there is end to end gastroduodenal anastomosis in billroth 1 there are more chances of anastomotic leak
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Ans. b (Strongyloides stercoralis) (Ref. H- 16th ed., p 1235, 1258; Table 192-2; Table 201-1)The Strongyloides stercoralis larvae inhabit duodenum of humans, attaching themselves to mucous membrane, causing inflammation, and eventually duodenal stricture results.SpeciesDisease/OrgansForm/ TransmissionDiagnosisTreatment...
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Ans is 'a' ie Autosomal dominant Hirschprungs ds or Aganglionic megacolon or Congenital megacolon is a congenital disorder d/t absence of ganglion cells in the neural plexus ie both myentric (Aurebach's) and submucosal (Meissner's) plexus of the intestinal wall. There is accompanying hyperophy of the nerve trunks. MC s...
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Prefilaggrin(precursor molecule) is found in the keratohyaline granules present in the stratum granulosum. Filaggrin is most abundantly present in Stratum corneum. Filaggrin - helps in filament aggregation
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Ans. b (Benzathine penicillin). (Ref. Pharmacology KD Tripathi 5th/657, 673, 688; Harrison's Medicine 16th/980)Rx of SyphilisEarly & latent syphilisLate syphilis1.2 MU Procaine penicillin x 10 daysOR2.4 MU benzathine penicillin 1-3 weeklyBenzathine penicillin2.4 MU weekly for 4 weeksDrug used for treatment of syphilis#...
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Immediate exposure to low PO2 stimulates the aerial chemoreceptors, and this stimulation increases alveolar ventilation to a maximum of about 1.65 times normal. Therefore, compensation occurs within seconds for the high altitude, and it alone allows the person to rise several thousand feet higher than would be possible...
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- the most efficient method to prevent plaque is control of rat flea. -immunisation with plaque vaccine is a valuable preventive measure. The WHO recommends that under all circumstances, vaccination should be used only for the prevention not the control of human plaque. - killed plaque vaccine is used. Reference : Park...
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Type II alveolar cells (type II pneumocytes or septal cells) are cuboidal cells interspersed among the type I alveolar cells. Type II cells divide to replace their own population after injury and to provide progenitor cells for the type I cell population. Lamellar bodies can be considered markers for type II cells. The...
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"Oesterogen predisposes to thrombosis and not progesterone" -
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Ans: a (Sperm count <20 million/c.mm) Ref: Bailey, 24th ed,p. 1416; Shaw, 13th ed,p. 202Oligospermia (Oligozoospermia)- Mild - 10 - 20 million/ c.mm- Moderate -5-10 million/ c.mm- Severe - <5 million/ c.mmAspermia -no semen.(anejaculation)Azoospermia -no sperm in semenAsthenospermia -no motile sperm or diminished motil...
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Ans. (c) 0 and 100Ref: K. Park 23rd ed. /17PQLI (Physical Quality of Life IndexHDI (Human Development Index)Literacy rateLiteracy rateInfant mortality rateIncomeLife expectancy (at 1 year)Life expectancy () birth)Range: 0 and 100Range: 0 and +1Value in India: 650.547Also Know* Range of correlation coefficient; 1 to +1
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Ans. A i.e. 1-3 hours Dose and time for infusion of Alteplase for Pulmonary embolism is 100 mg over 2 hours.
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The oral contraceptives are highly effective contraceptive method The failure rate is very low ( 0.3℅), as ovulation is inhibited
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"Sinus tachycardia is the most common arrhythmia in the perioperative period". ─ Miller
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Ans. is 'c' i.e., 512 Hz o Commonly used tuning fork has a frequency of 512 Hz-o Forks of other frequencies, e.g. 256 and 1024 Hz should also be available.
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ASHA payments :  6 visits in Institutional deliveries (Day 3,7,14,21,28,42)   7 visits in home deliveries (Day 1,3,7,14,21,28,42) Birth weight record Immunized with BCG, First dose of OPV & DPT  Birth registration Mother and child are safe.
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Ans. is 'a' i.e., Age of fetus Rule of Haaseo Hess's rule (Haase's rule) : It is a rough method for calculating the age of fetus by measuring the length from crown to heel.o Upto 5th month of gestation, length of foetus in cm is square of the month of gestation and beyound 5 months, length in cm is 5 times the month of...
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Ans. (D) MAT(Ref. Harrison's Principle of Internal Medicine 20th Ed; Page No-1733 and 1745)ECG shows narrow complex tachycardia with irregular rhythm.Since P waves are seen it rules out AEDifferent morphologies of P waves (>=3) in lead II rules out Sinus arrhythmia.All the above said features confirm MAT.Also absence o...
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In pheochromocytoma, there are paroxysms of hypeension and finally give way to continuous hypeensive state. During attacks, the patient complains of headache,palpitations,abdominal pain, and dizziness; pallor, vomiting, and sweating also occur. The child has a good appetite but because of the hypermetabolic state does ...
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Ans. D. Bullous pemphigoid* Acantholysis is not seen in Bullous pemphigoid.* Acantholysis is the loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes.Acantholysis may be either primary or secondary:Primary Acantholysis* Primary acantholysis is due to the rupture of ...
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Ans. a. Positive skewing (Ref: Simple Biostatistics by Indrayan and Indrayan Central Tendency in Various Districution/III)DistributionCentral TendencyNormal (Gaussian) DistributionMean = Median = ModeQRight (Positive) Skew DistributionMean > Median > ModeQLeft (Negative) Skew DistributionMean < Median < ModeQ In Distri...
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A normal individual without iron deficiency absorbs 5-10% of iron, or about 0.5-1 mg daily. Iron absorption in­creases in response to low iron stores or increased iron requirements In an iron deficient individual, about 50-100 mg of iron can be incorporated into hemoglobin daily, and about 25% of oral iron given as fer...
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Recovery of reflex excitability is due to the development of denervation hypersensitivity to the mediators released by the remaining spinal excitatory endings and the growing of collaterals from existing neurons with the formation of additional excitatory ending on interneurons and motor neurons. Flexor reflexes return...
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Ans. is 'a' i.e., Phenylanine hydroxylase Phenylketonuria# It is an inborn metabolism of phenylalanine, in which there is inability of oxidation of phenylalanine0 into tyrosine.There is defective function ofphenylalanine hydroxylase Q. which may be due to : -Classical phenylketonuria (hyperphenvlalanemia ty pe I) - Def...
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For a material to satisfy Hooke’s law, the elastic stress must be directly proportional to the elastic strain. The initial region of the stress-strain plot must be a straight line. Because direct proportionality between two quantities is graphically represented by a straight line, the linear portion of the graph in the...
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S.320, I.P.C. deals with Grievous Injury. Grievous Injuries: Emasculation Permanent privation of sight of either eye Permanent privation of hearing of either ear Privation of any member or joint Destruction or permanent impairing of the power of any member or joint Permanent disfiguration of the head or face Fracture o...
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The urea breath test is a rapid diagnostic procedure used to identify infections by Helicobacter pylori, a spiral bacterium implicated in gastritis, gastric ulcer, and peptic ulcer disease.  It is based upon the ability of H. pylori to convert urea to ammonia and carbon dioxide.
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A. i.e. Benign Familial Chronic Pemphigus
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Ans. is 'a' i.e., Dense fibrous septae Pulp space infection (felon) Pulp space infection with pus trapped between the specialised fingeip septae causes intense fingeip pain. It may lead to terminal phalangeal bone infection, erosion and sequestrumformation.The last of these will need to be drained and debrided. A commo...
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Infective meningitis is mainly due to Staphylococcus epidermidis carried along with needle from skin. Spinal epidural abscess (SEA) in children is a rare infectious emergency warranting prompt intervention. Predisposing factors include immunosuppression, spinal procedures, and local site infections such as veebral oste...
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Insecticides are substances used to kill insects.They are 3 gruops: contact poison,stomach poison,fumigants. Contact poisons- BHC,DDT,lindanediazinon,malathion,fenthion. Stomach paoisons are paris green and sodium flouride . Fumigants are hydrogencyanide,methyl bromide,sulpher dioxide. Parks textbook of preventive and ...
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Information in this question are : - H/O trauma with vegetative matter Mild symptoms, with greater signs Feathery and hyphate ulcer margin Satellite lesions The diagnosis is a fungal corneal ulcer, which can be caused by Aspergillus, Candida or Fusarium.
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Treatment of hepatic encephalopathy 1. Correct precipitating factors 2. Use lactulose- results in colonic acidification. 2. Poorly absorbed antibiotics- neomycin and metronidazole. More recently, rifaximin at 550 mg twice daily has been very effective in treating encephalopathy without the known side effects of neomyci...
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CDKN2A is a complex locus that encodes three different tumor sup- pressors, p15/INK4b, p16/INK4a, and p14/ARF. Of these, loss of p16/INK4a is clearly implicated in human melanoma, and experimental evidence also suppos a role for loss of p14/ARF. As already mentioned, p16/ INK4a inhibits cyclin-dependent kinase 4 (CDK4)...
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Ans. is 'b' i.e., Endotoxin Fulminant meningococcemia (purpura fulminans or Waterhouse - Friderichsen syndrome) is the most rapidly lethal form of septic shock experienced by humans. It differs from most otherform ofseptic shock by the prominance of hemorrhagic skin lesions (petechiae, purpura) and the consistent devel...
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Dental infections are an impoant source of maxillary sinusitis. Roots of premolar and molar teeth are related to the floor of sinuses and may be separated only by a thin layer of mucosal covering. A peripheral dental abscess may burst into the sinus or the root of a tooth during extraction may be pushed into the sinus....
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The deep perenial pouch includes deep transverse perineal pouch,membraneous poion of urethra,bulbourethral gland.Deep perineal pouch is the anatomic spacde enclosed by perineum and located superior to the perinial membrane. ref - BDC vol2 6e pg 355,360
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The epiglottis is a leaf shaped elastic cartilage situated behind the root of tongue.
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Ans. is a i.e. Yolk sac Fetal structure Detected by TVS Detected by TAS Gestational sac 4 weeks 5 weeks Yolk sac 5 weeks 7 weeks Cardiac activity 5.1 - 6.5 weeks 8 weeks Embryonic movement 7 weeks
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Ans. is 'd' i.e., Tretinoin o Tretinoin causes chest pain, pleuritis, pulmonary infiltrates and pleural effusion. It is a known human teratogen. Daunorubicin and doxorubicin cause cardiotoxicity manifested as arrhythmias and CHF.
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Ans. is 'a' i.e., Xenon Xenon It exes anaesthetic action by non competitive blockade of NMDA receptors. Xenon has been used as a general anesthetic. Xenon interacts with many different receptors and ion channels and like many theoretically
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Ans. C. PepsinogenThe chief cells of the stomach secrete pepsinogen, and the parietal cells of the stomach secrete hydrochloric acid and intrinsic factor. Gastrin and CCK are secreted by specialized endocrine cells.
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anaphylactoid reactions usually manifest in the skin and gastrointestinal, respiratory, and cardiovascular systems. Primary symptoms and signs include pruritus, uicaria, nausea, vomiting, abdominal cramps, bronchospasm, laryngeal edema, and, occasionally, anaphylactic shock with hypotension,and death. They occur within...
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Resuscitation following blood loss from multiple fractures begins with administration of 2-3 litres of isotonic crystalloid immediately to restore BP and peripheral circulation Lactated ringer (RL) solution is generally preferred over 0.9% NaCl (normal saline) as it is balanced salt solution and designed to mimic extra...
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Dysgerminoma
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Ans. (c) Cervical spineRef.'.MR Imaging of the Spine and Spinal Cord by DetlevUhlenbrock p-375, Orthopedic surgery essentials- Spine by Christopher M. Bono, Steven R. Garfin p-188
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The kidneys lie along the veebral column lying against the psoas major muscle extending from the first to the fouh lumbar veebrae. They lie exclusively within the retroperitoneal space. The renal aeries arise from the aoa. The right renal aery passes behind the inferior vena cava, entering the kidney at the hilus where...
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Hyperkalemia pro- duces a sequence of changes (), usually beginning with nar- rowing and peaking (tenting) of the T waves. Fuher elevation of extra- cellular K+ leads to AV conduction disturbances, diminution in P-wave Ref Harrison 20th edition pg 1421 amplitude, and widening of the QRS interval.
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Ans. is 'd' i.e., Streptomycin Important educational points* First line antitubercular drugs causing hyperuricemia - Ethambutol, pyrazinamide.* Drugs causing peripheral neuropathy - streptomycin, INH, Ethambutol, ethionamide.* Drugs causing hepatitis - INH, rifampicin, pyrazinamide, ethionamide.* Optic neuritis - INH, ...
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Ans. B. Lead ZirconateLead Zirconate titanate (PZT) is the most widely used material in the ultrasound transducers/probes replacing the previously discovered barium titanate.
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Dysphoric mood, Nausea, Vomiting, Lacrimation, Muscle aches, dilated pupils, sweating, yawning, fever and insomnia are the symptoms of opioid withdrawal. Heroine is the commonest opioid misused. Withdrawal is due to reduced intake or abstinence following many weeks of continuous intake Ref: DSM IV : Diagnostic Criteria...
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Ans. is 'c' i.e., Lower medial Basal cell carcinoma is the commonest malignant tumor of the lids (90%) usually seen in elderly people. It is locally malignant and involves most commonly lower lid (50%) followed by medial canthus (25%), upper lid (10-15%) and outer canthus. "Basal cell carcinoma is seen in the lower lid...
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Ans. is 'b' i.e.. Agarose gel electrophoresis o DNA is cut into large fragments, using restriction enzymes. These fragments are then separated by gel electrophoresis (either agarose or polyacrylamide gel electrophoresis).
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Ans. Organophosphorus
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Herpes zoster keratits occurs in 40% of all patients sometimes may precede the neuralgia or skin lesions. in several forms.1)Epithelial keratitis 2)Nummular keratitis 3)Disciform keratitisReference:Comprehensive ophthalmology,AK Khurana,6th edition,page no.106
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Ans. is 'b' i.e., Trophozoites in the pus
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Essential tremor Most common of all movement disorder. Higher in frequency and lower in amplitude than the tremor of PD. May be a form of enhanced physiological tremor, but recent evidence suggests a cerebellar abnormality. Often familial. Postural and action tremor that tends to affect the hands, head, and voice. Made...
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Refer Robbins page no 758-759 External beam irradiation but not mediastainal fibrosis is a risk factor for esophagal cancer *HPV DNA is found frequently in esophagal squamous cell carcinoma in high incidence
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Expiratory valve is away from the patient end in mapleson D circuit. 3 times minute ventilation is required for spontaneous ventilation. Mapleson A is the preferred circuit for spontaneous ventilation.
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Ans. is 'b' i.e., Liver Poal vein is a vein, still it supply blood to liver (usually a vein drains blood from an organ or tissue). The liver has dual blood supply :- 20% of blood supply is through the hepatic aery. 80% of blood supply is through the poal vein.
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Ans. is 'a' i.e., About 95% of the girls have PEFR between 260 and 340 1/min o 1 SD includes --> 68% of values o 2 SD includes --> 95% of values o 3 SD includes --> 99.7% of values In this question Mean PEFR = 300 L/min SD = 2 L/min i) Area around 1 SD on either side of mean (x 1 SD) will include 68% of values, i.e. x+...
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Lymphomas of the thyroid are fast growing tumors, not slow growing. It usually present with as a goitre that has grown significantly over a sho period. Ref: Harrison's Principle Of Internal Medicine, 16th Edition,Page 2126/ 18th edition chapter 341.
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Nohern blot is used to analyze RNA Southern blot-DNA Western blot- proteins Ref: Textbook of Microbiology Baveja 5th ed Pg 120
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Flavoproteins are impoant components of Complexes I and II. The oxidized flavin nucleotide (FMN or FAD) can be reduced in reactions involving the transfer of two electrons (to form FMNH2 or FADH2), but they can also accept one electron to form the semiquinone. Ref: Harper 28th edition, chapter 13.
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The kidney is innervated primarily by the sympathetic nervous system and as such, regulates the contraction of the smooth muscle surrounding the afferent and efferent aerioles of the glomerulus. Sympathetic stimulation to the efferent glomerular aerioles causes the constriction and increases the filtration rate, leadin...
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Pneumocystis [Ref: Harrison I7/e p843; Aicle 'Tree in bud sign' in Journal 'Radiology' and 'Radiographics7 Tree-in-bud is a sign seen in HRCT, most commonly seen with endobronchial spread of Tuberculosis, but can be seen with a wide variety of conditions, most commonly infections. (Described ahead in detail). Theoretic...
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Seven implant treatment options are available for Division C bone:  Osteoplasty (C-w bone) before implant insertion  Root-form implants  Subperiosteal implants (C-h and C-a bone in mandible)  Augmentation procedures  Disk design implants (posterior mandible or anterior maxilla)  Ramus frame implants (C-h bone, complet...
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(Ref: KDT 6/e p444) Imipramine is a tricyclic antidepressant. It inhibits the reuptake of serotonin and nor-adrenaline. In addition, it possesses anticholinergic and a-blocking propeies are: Increased risk of seizures due to lowering of Seizure threshold is an adverse effect of this drug.
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AXILLARY NERVE SUPPLY : Posterior cord lower border of pectoralis minor Quadrilateral space Upper lateral cutaneous nerve of arm supplies skin over lower half of deltoid Nerve to deltoid Nerve to teres minor Injury results in loss of sensation over the lower half of the deltoid Weakness of the deltoid and the teres min...
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Ans. is 'b' i.e., Increased free radical injuryFree radical (reactive oxygen species) mediated damage is one of the impoant factor that contribute to cellular aging. The rate at which antioxidant system (catalase, peroxidas and superoxide dismutase) is synthesized declines with cell aging.About other optionsCross linka...
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Actinomycosis is most commonly caused by Actinomyces israelii. It is characterized by the presence of abscess with sinus tracts leading to the skin. Ref: Diagnostic Radiology : Musculo-Skeletal and Breast Imaging By Jaypee Brothers, 2nd Edition, Page 141.
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Among the given drugs -hirsutism i. e excessive hair growth feature is shown by minoxidil which is used in a therapeutic manner whereas hirsutism is shown by phenytoin and coicosteroid as an adverse effect cause of increased use. But heparin does not show a feature of hirsutism phenomenon ESSENTIALS of medical PHARMACO...
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Answer is B (Increased protein in CSF): Pseudotumor cerebri is associated with a normal CSF picture. Pseudotumor cerebri It is a benign self-limiting disorder with a orable outcome. Characteristic features: Elevated intracranial pressure (intracranial hypeension) with : Normal or Small sized ventricular system No focal...
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Secondary prevention aims to detect and treat a disease early In RF, secondary prevention includes identifying those who have had RF and giving them inj benzathine penicillin (1.2 million units in adults and 600,000 units in children) at intervals of 3weeks. This must be continued for 5years or until the child reaches ...
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Ans. is 'b' i.e., Hepatic cyst and fibrosis o The clinical findings suggest autosomal recessive polycystic kidney disease. o The diagnosis of autosomal recessive polycystic kidney disease is strongly suggested by bilateral papable flank masses in an infant with pulmonary hypoplasia, oligohydramnios and hypeension and t...
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Disinfection is the destruction or removal of all pathogenic organisms or organisms capable of giving rise to infection Including spores Ref Ananthanarayan & paniker's textbook of Microbiology 9th edition page no 28
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