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Ans. is 'c' i.e., Inhbition of 11b-Hydroxylase o Metyrapone inhibits 1113-Hydroxylase in adrenal coex and prevents synthesis of hydrocoisone.
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Benefits of higher lactose content of breast milk: The galactose helps in formation of galactocerebrosides. Lactose helps in absorption of calcium |growth of lactobacilli in the intestine.
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85deg
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i.e. (Meckel's Cartilage): (316-109 IBS- Embryology 8th)* Malleus and Incus are derived from the dorsal end of the Meckel's cartilage (First arch)*** Stapes is formed from the dorsal end of the cartilage of second pharyngeal archNerves of pharyngeal arches and muscles supplied by themArchNerve of ArchMuscles of ArchCar...
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Refer KDT 6/e p827 Bleomycin can cause pulmonary fibrosis It should be avoided in patients of lung disease
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Ans. (d) AnaphylaxisRef: Harrison 19th ed. / 2116The life-threatening anaphylactic response of a sensitized human appears within minutes after systemic exposure to specific antigen and is manifested by* Respiratory distress due to laryngeal edema* Intense bronchospasm* Vascular collapse, or by shock without antecedent ...
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Ans. is 'b' i.e., Vasomotor rhinitiso Vasomotor is a nonallergic condition that involves a constant runny nose, sneezing and nasal congestion, i.e., the nose is stuffy or runny for reasons other than allergies and infections. The exact etiology is unknown, but triggers include emotions, odors, poor air quality, spicy f...
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Cystic blow out' is a type of biliary duct injury in cholecystectomy patient. According to Strasberg classification it falls into Type A injury. Ref: Complication in Surgery By Michael W. Mulholland, Gerard M. Dohe, 2nd Edition, Page 432
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All local anaesthetics are vasodilators except cociane which is a vasoconstrictor
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Ans. is 'a' i.e., Na+ channel inhibition * Local anesthetics act by inhibiting Na+ channels from inside.Mechanism of action of LA* Local anesthetics act by blocking Na+ channels. By blocking Na+ channels they block nerve conduction by decreasing the entry (Influx) of Na+ ions during upstroke of action potential.* LAS p...
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Ans. is 'a' i.e.. Rat Transmission of leptospireso Leptospirosis has been associated writh three lR's.1. Rats-# Rodents, especially rats, are the most important reservoir.2. Rice fields-# Farm workers represent the group at highest risk - Green wrood 1 b'Ve 356 # Certain occupational groups such as agricultural workers...
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* Risk of immunization by spontaneous complete miscarriage before 12weeks without any need for evacuation of products is negligible, hence ant D Ig is not required * There is evidence that significant fetomaternal haemorrhage occurs after cuettage of products but not in spontaneous complete miscarriage * Anti D Ig shou...
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Malaria recrudescence: Reappearance of sexual stage parasitemia after treatment as shown by – Plasmodium falciparum – Plasmodium malariae
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Answer is A (Acute tubular necrosis) The most impoant toxity of cisplatinum is renal impairment - KDT 7th/777 Acute tubular necrosis is a manifestation of renal impairment and hence the answer.
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Sphingolipids: They comprise another group of lipids found in biological membranes especially in the tissues of nervous system. There are three types of sphingolipids sphingomyelin, cerebrosides and gangliosides. About 6 percent of the membrane lipids of grey matter cells in the brain are gangliosides.Ref: Textbook of ...
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ZOE is finely divided and contains minimum amount of water. Eugenol may cause burning sensation on contact with oral mucosa in sensitized persons.
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Ans. is 'a' i.e., Meckle's cailageEach half of the mandible ossifies from only one centre which appears at about the 6th week of intrauterine life in the mesenchymal sheath of Meckels cailage near the future mental foramen. Meckle's cailage is the skeletal element of first pharyngeal arch.
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ANSWER: (A) CrystalloidsREF: Schwartz's Principles of Surgery 9th ed chapter 5"Fluid resuscitation is a major adjunct to physically controlling hemorrhage in patients with shock. The ideal type of fluid to be used continues to be debated; however, crystalloids continue to be the mainstay of fluid choice"Several studies...
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Ans. is `d' i.e., Etoposide
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C. i.e. Rt kidney is preferred over left kidney for transplantation- Left kidney is usually choosen for transplantation because it has longer renal vein which simplifies transplant operation.Q- Transplanted kidney is placed in iliac fossa, in the retroperitoneal position leaving native kidney in situ.- Renal vein is an...
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In a competitive inhibitor, the curve will shift to right while in non-competitive inhibitor there will be flattening of DRC.
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The cells described are asteroid bodies, and are classically associated with sarcoidosis, although they are not completely specific for this disease. Anitschkow cells are a form of activated histiocyte with an unusual wavy chromatin. They are found within inflammatory lesions called Aschoff bodies in the heas of patien...
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The synopsis of forensic medicine & toxicology;Dr k.s narayan reddy; 28th edition; pg.no.155; It is an assault coming under S.351,I.P.C
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Hemorrhage
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Glucose 6 phosphate dehydrogenase  NADPH is produced during HMP shunt by two enzymes:- (i) Glucose-6-phosphate dehydrogenase, and (ii) 6-phosphogluconate dehydrogenase.
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Ans. (a) Vitamin B12* Deficiencies in SBS:# Bile salt malabsorption# B12 deficiency (Most common)# Fat soluble vitamin deficiency# Steatorrhea (Fat loss)
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Ans. Any of the above
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Pupils are bilaterally symmetric, small and irregular.
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Ans. C: Socialization Acculturation is the exchange of cultural features that results when groups of individuals having different cultures come into continuous first hand contact; the original cultural patterns of either or both groups may be altered, but the groups remain distinct. Socialization is the process by whic...
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In the past, restriction of dietary protein was considered for patients with encephalopathy; however, the negative impact of that manoeuvre on overall nutrition is thought to outweigh the benefit when treating encephalopathy, and it is thus discouragedHydration and correction of electrolyte imbalance are all that is ne...
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Peutz-Jegher's syndrome - Multiple hamaomatous polyps in S.I - M/C pa - Jejunum- Gene- LDB-1 / STK-11 - 19p- Hyper melanotic macules over Lips &Buccal mucosa - Does not |risk of colorectal cancer- | risk of S.I. malignancy- | risk of- Breast - Thyroid- Pancreas (max risk)- Endometrial - Seoli cell tumor of testis
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MC type of hernia in males: Indirect inguinal hernia Femoral hernia is more common in females than in males but in females most common is indirect inguinal hernia. MC type of hernia in females: Indirect inguinal hernia Direct inguinal hernia is more common in the elderly
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Avascular necrosis - osteonecrosis of the femoral head may occur even if the hip is not fully dislocated. The condition is probably overdiagnosed because of an erroneous interpretation of x-ray appearance following impacted marginal fractures of the acetabulum. Other complications : *iliofemoral venous thrombosis *sci...
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The Recurrent laryngeal nerve lies very close to the inferior thyroid aery near the base of the thyroid lobe.
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Vossius ring: It is a circular ring of brown pigment seen on the anterior capsule. It occurs due to striking of the contracted pupillary margin against the crystalline lens due to blunt trauma. It is always smaller than the size of the pupil. Ref:- A K KHURANA; pg num:-405
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Von Willebrands Factor
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Significant variations in attainment of milestones in different developmental domains is called 'Dissociation'. Dence- Acquisition of milestones in a sequence that is different from the usual Ex: Walking may come before crawling in cerebral palsy. Delay is when child does not reach their developmental milestones at the...
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Ans. B: Methyl alcohol Fomepizole or 4-methylpyrazole is indicated for use as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. It may be used alone or in combination with hemodialysis.
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Binding of aminoacyl-tRNA to the A sitea. The mRNA codon at the A site determines which aminoacyl-tRNA will bind.(1). The codon and the anticodon bind by base-pairing that is antiparallel (see Figure below).(2). Internal methionine residues in the polypeptide chain are added in response to AUG codons. They are carried ...
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Posterior Cricoarytenoid Muscle: The posterior cricoarytenoid muscle arises from the posterior aspect of the cricoid cailage and courses upward and laterally to attach to the muscular process of the arytenoid cailage. Its contraction pulls the muscular process backward and rotates the arytenoid cailage around a veical ...
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Central chemoreceptors are situated in the deeper pa of medulla oblongata, close to the dorsal respiratory group of neurons. This area is known as a chemosensitive area, and the neurons are called chemoreceptors. Chemoreceptors are in close contact with blood and cerebrospinal fluid. Central chemoreceptors are connecte...
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Immunoproliferative small intestinal disease (IPSID) was recently added to the growing list of infectious pathogen-associated human lymphomas. IPSID lymphomas reveal excessive plasma cell differentiation and produce truncated alpha heavy chain proteins lacking the light chains as well as the first constant domain Abdom...
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Ans. A. Gluconeogenesis(Ref: Harper 31/e page 172)Gluconeogenesis takes place in cytosol and mitochondria.The Mitochondrial step is Pyruvate Carboxylase reactionPathways taking place in two compartments areHeme SynthesisUrea CycleGluconeogenesis
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Ans. is ' c' i.e., Hepatitis B o TT, OPV and measles are given in National immunization schedule. Hepatitis B vaccine has also been included in recent time.
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Ans. a (Young boy) (Ref. Reddy's essentials of FMT 23rd 1346)Sodomy (buggery) is anal intercourse between two males or, between a male and female. It is also called buggery. It is called gerontophilia when the active agent is an adult and paederasty, when the passive agent is a young boy, who is known as catamite.# A p...
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Delayed prolonged leakage is believed to be caused either by the direct effect of injurious agent or by cytokine mediated endothelial retraction. It is not caused by cytokine mediated vasodilatation and cytokine mediated endothelial retraction is not provided in the options. Direct effect of injuring agent is therefore...
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Elation (moderate elevation of mood): A feeling of confidence and enjoyment, along with an increased psychomotor activity. Elation is classically seen in mania. Reference: A sho textbook of psychiatry by Ahuja, page 70. Emotion derives from basic drives, such as feeding, sex, reproduction, pleasure, pain, fear, and agg...
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Ans. is c, i.e. Pelvic examination in OTRef. Dutta Obs. 7/e. p 249Patient is presenting with painless vaginal bleeding and uterus is soft and nontender. These findings point towards the diagnosis of placenta previa (In abruptio-bleeding is accompanied by pain, uterus is tense, tender and rigid).The gestational age of p...
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Survey Education and Treatment (SET) Centre →  Was advised where prevalence was 1-5 per 1000. A SET Centre is attached with: PHC in rural area Administrative control: Medical Officer (PHC) Population catered: 20,000 — 25,000 Staff One paramedical worker Functions: Detection of cases early by house-to-house survey He...
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Ans: d (Digoxin) Ref: Nelson, 17th ed, p. 2048 & OP Ghai, 6th ed, p. 530Pseudo tumour cerebri is a clinical syndrome that mimics brain tumours and is characterized by increased intra cranial pressure with a normal cerebrospinal fluid cell count and protein content and normal ventricular size, anatomy and positionCAUSES...
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Ans. is 'd' i.e., Megaloblastic anemia Macropolymorphonuclear (Macropolycytes) - Neutrophils in megaloblastic anemias are larger than normal (macropolymorphonuclear) and hypersegmented that is they have 5-6 more nuclear lobes.
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XLD (xyloseJysine deoxycholate) agar is a selective differential medium for isolation of Gram-negative enteric pathogens from fecal specimens and other clinical material. o It is especially suitablefor the isolation of shigella and salmonella specias REF : ananthanarayana 10th ed
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The most common cranial nerve involved in GBS is the 7th cranial nerve involvement BUT the question was regarding cranial nerve involvement causing ophthalmo-paresis in G.B.S. Hence the Answer is a 6th cranial nerve. Remember the number 7-6-3 as cranial nerves involved in G.B.S. Ophthalmoparesis may be observed in up t...
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A i.e. Glandular form of acne rosacea
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Ans. is 'b' i.e., Acute glomerulonephritis o None of the option is correct because most common cause is chronic glomieulonephritis. o But, amongst the given options acute glomerulonephritis is the most common disease that progresses to chronic glomerulonephritis.
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Coarctation of the aoa occurs in two patterns. In the infantile type, the stenosis is proximal to the inseion of the ductus aeriosus (preductal); this pattern is associated with Turner's syndrome. In the adult form, the stenosis is distal to the ductus aeriosus (postductal) and is associated with notching of the ribs (...
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CMB also called Robesons cooked meat -contains nutrient broth and cooked meat of ox hea Saccharolytic reaction positive for cl.perfringes Proteolytic reaction positive for cl.tetani Ref: CP Baveja 4th ed Pg:51
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. Wilms&; tumour
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Anaplastic large cell lymphoma is characterized by the presence of large bizarre cells, called Hallmark cells, with the embryo or horseshoe-shaped nuclei.
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(D) Preserved postural reflexes # In Parkinsonism the postural reflexes are not preserved. There is difficulty in maintaining balance, the posture is stopped and the attitude is flexed.# Clinical features of Parkinsonism> General: Masked face Stuped posture/flexed attitude Slurred indistinct speech> Bradykinesia Diffic...
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Answer is C (Cerebellar Astrocytomas): Most cerebellar astrocytomas are histologically Juvenile pilocytic astrocytomas. Juvenile pilocystic astrocytomas are benign and non infiltrating astrocytomas with an excellent prognosis (95% 5 year survival with surgery alone) Ependymomas are also histologically benign but carry ...
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During embryogenesis, hematopoiesis occurs in spatially and temporally distinct sites, including the extraembryonic yolk sac, the fetal liver, and the preterm marrow. The development of primitive erythroblasts in the yolk sac is critical for embryonic survival. After 7 weeks' gestation, hematopoietic progenitors are no...
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Ans. is 'a' i.e., FEV1 / FVC < 0.7 The lung function tests in obstructive lung disease can be summarized as -o Forced expiratory vital capacity (FEVc)- Normal to slightly decreasedo Forced expiratory volume in 1 secQ (FEV )-Decrease out of proportion to FVCo FEV1/FEV1Q-Decrease can be as low as 20% - 30%o Peak expirato...
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The obstetric conjugate is the shoest distance between the promontory of the sacrum and the symphysis pubis. It generally measures 10.5 cm. Because the obstetric conjugate cannot be clinically measured, it is estimated by subtracting 1.5 to 2 cm from the diagonal conjugate, which is the distance from the lower margin o...
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Ans. A. Paclitaxel and carboplatin for six cyclesAdjuvant therapy for ovarian cancer:a. Stage I, grade 1 = no adjuvant chemotherapy after complete staging laparotomyb. High grade, high risk stage I = carboplatin + paclitaxel for 3 - 6 cyclesc. Advanced ovarian malignancy = treatment is surgical debulking followed by ch...
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USG is the investigation of choice for molar pregnancies.
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Early ambulation after major operation is a protection against deep vein thrombosis, which helps in disability limitation. Teiary level of prevention- applied when disease has advanced beyond early stages. It aims to reduce or limit disabilities & help in rehabilitation. Rehabilitation is restoration of an individual t...
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This is a case of brachial neuritis following an injection of tetanus toxoid. Here there is dysfunction of the nerves supplying the arm or shoulder without involvement of the rest of the nervous system. The sensory loss is less prominent than the weakness. There may also be bilateral involvement of muscles with wasting...
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(A) Involvement up to muscularis propria # Duke's prognostic classification> A-growth in colon/rectum only> B-growth extending to extrarectal tissues but no metastasis to regional lymph nodes> C-secondary deposits in regional lymph nodes
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Option 1, 2, 4 Lyme's disease Causative agent = B. burgdorferi Transmitted by bite of Ixodid ticks /Hard tick Replicates locally & invades locally Centre - periphery Erythema Chronicum migrans Annular rash / bull's eye. Associated with ch. ahritis Option 3 B. recurrentis: causes Relapsing fever Reason for relapse is an...
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Ans. A i.e. Fats and oils Food pyramid The bottom of the pyramid, the biggest pa, is the Bread, Cereal, Rice and Pasta Group. This pyramid shows that this should be taken in most servings per day. The top pa, the Fats, Oils and Sweets Group is the smallest. This shows that we shouldn't have too much fat or oil in our d...
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Cardiac anomalies in Congenital rubella (In decreasing order of frequency) → PDA (most common), PS, VSD, ASD ASD is the best answer amongst the given options because, amongst the given options, ASD is least commonly associated with congenital rubella.
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Eating the own contents of cell is called as autophagy.
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Whiff test positive
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Ans. C: Cleft lip and cleft palate The typical distribution of cleft types is: Cleft lip alone-15% Isolated cleft palate-40% Cleft lip and cleft palate-45% Cleft lip alone (hare lip): It is due failure of fusion between the frontonasal (philtrum) and the maxillary processes. Types : - Unilateral 85% usually on the left...
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Casoni's test is used in the diagnosis of Hydatid disease, caused by Echinococcus granulosus. In this test, 0.2ml of sterile hydatid fluid is injected intradermally into one arm. This test is considered to be positive if large wheal, 5 cm in diameter with multiple pseudopodia develop in 30 minutes. Other test used to d...
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The MC anomaly is right subclan aery arising from the descending aoa and travels behind the esophagus to complete its course to the right upper extremity, may cause significant posterior compression of the esophagus Ref : ENT textbook by Dhingra 6th edition Pgno : 447
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Hyperplastic aeriosclerosis
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Types of Bevel
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Ans. is 'c' i.e., Pellagra Pellagra* Pellagra, the classic niacin deficiency disease, occurs chiefly in populations where corn (maize), a poor source of tryptophan, is the major foodstuff". A severe dietary imbalance, such as in anorexia nervosa and in war or famine conditions, also can cause pellagra.* Pellagra can al...
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Ans. B. t-RNAAnticodon is a code which codes for a specific amino acid and is present on t-RNA.Complementary codon is present on m-RNA. The structure of t-RNA is known as clover leaf like. It has mainly four arms.
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Membrane when punctured by microneedle is healed by lipids Resealing by lipid bilayer
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Titin is the muscle spring It is a suppoive protein It extends between zline and m line Ref:Guyton and Hall textbook of medical physiology 12th edition,page number: 86,87
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Ans. is 'b' i.e., t (9 ; 22) o It is a case of chronic myeloid leukemia o First lets discuss the hematological findings in CML. CML is characterized by proliferation of cells of the granulocyte series that have matured beyond the myeloblast stage. Bone marrow cells are primarily of myeloid or megakaryocyte lineage with...
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Ans. Sunflower cataract
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Pruning: * Programmed elimination during development of neurons, synapses, axons and other brain structures The fetal brain has more neurons generated than required for adult life The reduction is to remove all the unnecessary cells or cells which have already served their function
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Ans. is 'b' i.e., Sperm motility (not sure)
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Complications of adeniodectomy: Haemorrhage Injury to eustachian tube opening Injury to pharyngeal musculature and veebrae Griesel syndrome Velopharyngeal insufficiency Nasopharyngeal stenosis Recurrence Ref: Dhingra 7e pg 491
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Wallerian, or anterograde degeneration Occurs toward the distal end of the axon in both the CNS and PNS Characterized by successive fragmentation and disappearance of axons and myelin sheaths and by secondary proliferation of Schwann cells. Retrograde degeneration occurs toward the proximal end of the axon and in the c...
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Ans. is 'a' i.e., Bronchial smooth muscle Smooth muscles have muscarinic receptors (M3 type).
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Inspiratory Reserve volume It is the amount of air in excess of tidal inspiration that can be inhaled with maximum effort. Normal value : 3,000 ml.
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- Hereditary spherocytosis is associated with increased osmotic fragility because RBCs are spherical & unstable d/t defect in their cytoskeleton. Osmotic fragility curves of normal and hereditary spherocytosis red blood cells.
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MAOI * IMPOANCE First class of antidepressant drugs that were introduced * MECHANISM There are three monoamines namely dopamine, adrenaline and serotonin. These mon amines are degraded by monoamine oxidase. MAOI inhibit this enzyme and acts increasing monoamines * DRUGS Phenelezine Tranylcipromine * USE ATYPICAL DEPRES...
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Ans is 'c' i.e. Only single stage of lesion is present at a time The characteristic feature of chicken pox is "Pleomorphism ", that is, all stages of the rash (papules, vesicles and crusts) may be seen simultaneously at one time in the same area.Chicken poxIt occurs primarily in children <10 yrs of age.It is highly com...
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Ans. b. Neurocysticercosis
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SODOMY: Other names: 1. Greek love 2. Buggery 3. grantophilia -- when passive agent is adult 4. Paederasty -- when passive agent is child. Paedophil - Active agent - sexual activity with children below sexual age Catamite -- Passive agent -sexual activity with children below sexual age ref : narayanareddy
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Bacillus anthracis is a large gram-positive rod with square ends, frequently found in chains. It is non motile, whereas other members of the genus are motile. Spores are usually not seen in smears of exudate because spores form when nutrients are insufficient, and nutrients are plentiful in infected tissue. Also know: ...
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Ans. Episcleritis
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Bladder should be empty during a transvaginal ultrasound
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Granulomatosis infantiseptica is an intra-uterine infection of the newborn caused by listeria. The predominant feature of this condition is extensive focal necrosis affecting especially the liver and, less often, the lungs. The moality rate is very high. Occasionally meningitis may be associated with it. The organisms ...
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