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Transverse ridge connecting MB and ML cusps.
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Hypertension is present in up to 75% of patients over the age of 20 years with polycystic disease.
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Screening of HIV: Strategy 1: one out of three screening tests are used; Done for screening every blood unit before transfusion. Strategy II: Two out of three screening tests are used; Done for screening person who is symptomatic with any one of AIDS defining illness. Strategy III: All three screening tests are used; D...
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Ans. is 'b' i.e., Staphylococcus epidermidis Staphylococcus epidermidis* Most common coagulase negative staph, causing human infections.* It is present on normal human skin (where it is the most abundant bacterial species) as well as in the oropharynx and vagina.* It is a common cause of stitch abscesses.* It has a pre...
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Ans. is 'a' ie. Submucous oral fibrosis " Submucous oral fibrosis is a progressive ds. in which fibrous bands form beneath the oral mucosa. These bands progressively contract so that ultimately mouth opening is severly limited. Tongue movements may also be limited. This conditon is almost entirely confined to Asians. H...
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Answer- B.May cause CSF rhinorrheaLe Fo I (transverse)- crosses lower pa of nasal septum, maxillary antra and the pterygoid plates.Le Fo II (pyramidal)- passes through the root ofnose, lacrimal bone, floor oforbit, upper pa of maxillary sinus and pterygoid platesLe Fo III (craniofacial dysjunction)- There is complete s...
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Ceain industrial chemicals have been linked with bladder cancer. Chemicals called aromatic amines, such as benzidine and beta-naphthylamine, which are sometimes used in the dye industry, can causebladder cancer. ... Cigarette smoking and workplace exposures can act together to cause bladder cancer. The most common risk...
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The Baczol Antigripal ingredients included the sulfonamide-containing antibiotic trimethoprim-sulfamethoxazole (TMP/SMX), which is a common cause of fixed drug eruption. In June 2013, another Salvadoran-American child, a girl aged 14 years living in nohern Virginia, was evaluated for a similar fixed drug eruption likel...
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Shaking a baby or young child creates abrupt acceleration-deceleration forces as the baby's head--large in propoion to the neck and body--snaps back and foh. The triad associated with SBS usually comprises subdural haematoma, retinal haemorrhages and encephalopathy.
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Isolated finding of simian crease in Down's in seen in almost 1% of Down's children. So it is not a significant finding in a Down's child.
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Ans. is 'c' i.e., Capsular polypeptide protein is responsible for virulence Pathogenicity of H. influenzae H. influenzae does not secrete any exotoxins, the polysaccharide capsule (not polypeptide) is considered to be the major factor in virulence. There are "6" types of capsule designated a,b,c,d,e, and f Of these, ty...
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Inflammatory infiltrates are virtually localized within the walls of the alveoli.
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Ans. is 'a' i.e., Phenylketonuria o Phenylketonuria is characterized by inability of oxidation of phenylalanine into tyrosine.Phenylketonuriao It is an inborn metabolism of phenylalanine, in which there is inability of oxidation of phenylalanine into tyrosine. There is defective function ofphenylalanine hydroxylase, wh...
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Anti mullerian hormone defeciency causes persistance of mullerian ducts and are stimulated to form uterine tubes,uterus,cervix and upper vagina LANGMAN'S MEDICAL EMBYOLOGY,12 TH EDITION, Pg no:247
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Brain is m/c site of metastasis of lung carcinoma. Adrenal is m/c endocrinal site to be involved.
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Ans. is 'b' i.e., Lasegue test Clinical examination in PID Forward stooping (bending), twisting or coughing aggravate the pain. The trunk is tilted to one side (sciatic scoliosis or sciatic tilt). Movements of lumbar spine are restricted especially flexion. Straight leg raising (SLR) test is positive, i.e. straight leg...
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Thumbprint sign is a finding on lateral cervical spine radiograph that suggest diagnosis of epiglottitis. This appearance is due to thickening of aryepiglottic folds, which causes it to appear more radiopaque, resembling the distal thumb. Also know Thumbprint sign is also seen in the colon in following diseases :- (1...
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Ans. is 'd' i.e., 200000 IU * For treatment of vitamin A deficiency, oral vitamin A is given at a dose of 50000 IU, 100000 IU and 200000 IU in children <6 months, 6-12 months and > 1 year, respectively.* The same dose is repeated next day and 4 weeks later.
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Ans. A. TolvaptanTolvaptan:Vasopressin antagonists.Orally active nonpeptide selective V2 receptor antagonist.Metabolized by CYP3A4 - Not given to patients receiving this isoenzyme inhibitor.Given once daily.t 1/2 : 6-8 hours.Actions:Increases free water clearance by kidney (aquaretic).Corrects lower plasma Na+ levels.U...
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Ans. is 'b' Carbamazepine -breech presentation, * Teratogenic effects of Antiepileptic drugsDrugsTrimesterEffect1. Barbiturates (Phenobarbitone)AllCongenital heart diseasesCleft lip, palate*Neonatal dependenceRespiratory depression2. ValproateAll* Neural lube defects*3. CarbamazepineAll* Neural tube defects4. Phenytoin...
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Ans. is 'a' ie. Rt. kidney is preferred ..... It is left kidney, not Rt. that is preferred for transplantation because it has a longer renal vein which simplifies the transplantation operation.
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hCG (Human chorionic gonadotropic hormone) has alpha and beta subunits. Its alpha subunit is similar to that of LH (leutinizing hormone), FSH (Follicular stimulating hormone) and TSH (Thyroid stimulating hormone) whereas beta subunits is specific. We have also studied that insulin hormone has alpha and beta subunits. R...
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D: Myocardial infarction can lead to cardiogenic shock. A: Option A is anaphylactic-shock B: Option B is neurogenic-shock C: Option C is hypovolemic-shock
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SARI * IMPOANCE antidepressant with good sleep, no sexual problems and no GI side effects. It was thought this would replace SSRI but dint do well because of notorious side effects * MECHANISM Serotonin antagonist and reuptake inhibitor * DRUGS Trazodone Nefazodone * USE low dose trazodone is used as a hypnotic * SIDE ...
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Clostridium tetani is a gram-positive, slender bacillus. It occurs singly and occasionally in chains. The spores are spherical, terminal and bulging, giving the bacillus the characteristic 'drumstick' appearance. Reference: Textbook of Microbiology; Anathanarayan and paniker's; 10th edition; Page no: 264
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In ventilation of the middle ear cleft, air passes from eustachian tube to mesotympanum, from there to attic, aditus, antrum and mastoid air cell system. Any obstruction in the pathways of ventilation can cause retraction pockets or atelectasis of tympanic membrane, e.g.: Obstruction of eustachian tube degTotal atelect...
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Cat-scratch disease is a form of self-limited infectious lymphadenitis that most often is seen in children, typically "downstream" of lymphatic drainage from the site of an injury on a distal extremity. Hence axillary and cervical lymph node regions are most often involved. Cytomegalovirus infection is typically seen i...
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Social marketing Concept: Seeks to develop and integrate marketing concepts with other approaches to influence behaviors that benefit individuals and communities for the greater social good - Social marketing seeks to influence social behaviors not to benefit the marketer, but to benefit the target audience and the gen...
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Centre
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Percussion for splenic dullness is accomplished with any of three techniques described by Nixon, Castell or Barkun. Ref: Harisson, Edition - 18, Page - 468
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Chalcosis- It refers to the specific changes produced by the alloy of copper in the eye. Mechanism - copper ions from the alloy are dissociated electrolytically and deposited under the membranous structures of the eye. KF ring is due to deposition of copper under peripheral pas of descemets membrane of cornea. Fleische...
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The normal left ventricular diastolic pressure is 5 mmHg. A pressure gradient across the mitral valve of 20 mmHg due to severe mitral stenosis will cause a left atrial pressure of about 25 mmHg. With the loss of the atrial kick where has in advanced disease there is low pulse pressure Ref Davidson 23rd edition pg 434
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The only intermediate included in the list that the pathway of gluconeogenesis from glycerol has in common with the pathway of gluconeogenesis from lactate is glucose-6-phosphate. Glycerol enters gluconeogenesis as DHAP. Therefore, it bypasses the other compounds (pyruvate, oxaloacetate, malate, and PEP) through which ...
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ref Robbins 8/e p167,9/e p168 No Mendelian inheritance can be classified into following categories Trinucleotide repeat mutation Mitochondrial gene mutation Genomic imprinting Gonadalmosaicism
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These tubes come in three sizes, 4.0, 5.0 and 6.0mm. The size 5.0mm tube is the most commonly used. Microlaryngoscopy tube (MLT) vs. standard ETT The MLT is often used in place of a standard small diameter ETT to facilitate Direct Laryngoscopic procedures utilizing Microlaryngoscopy techniques. The surgeon prefers a sm...
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6 weeks following delivery
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Answer is D (usually associated with carditis) Erythema marginatum and sub cutaneous nodules are usually associated with carditis manifestation Erythema marginatum is a rare (< 3%) manifestation of Acute Rheumatic fever. Rash is charachteristically non pruiritic and almost never involves the face.
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*Toll like receptors are a type of "pattern recognition receptors" that recognize the microbe structural pattern and binds to it.*These receptors are present in cells involved in innate immunity like the epithelial barrier, macrophages, dendritic cells, and T-lymphocytes.*B-cells are involved in adaptive immunity and t...
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Ref: BD Chaurasia Human Anatomy vol 2 pg 125,127.
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Ambiguous genitalia at bih is a medical emergency, not only for psychological reasons for the parents but also because hirsute female infants with congenital adrenal hyperplasia (CAH) may die if undiagnosed. CAH is an autosomally inherited disease of adrenal failure that causes hyponatremia and hyperkalemia because of ...
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Ans. is 'b' i.e., Thallasemia Marked veical striations in a patient with thalassemia give the appearance of hair standing on end so called hair on end sign usually seen in Thalassemia major Kwashiorkor Triad of :- Psychomotor change Edema ( PEG) Growth retardant Hair changes - Changes include dyspigmentation, loss of c...
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Ans. Black eye
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The external jugular vein crosses perpendicularly the superficial surface of the sternocleidomastoid muscle directly under the platysma muscle. The anterior jugular descends near the median line. The posterior auricular joints the retromandibular to form the external jugular. The internal jugular runs in the carotid sh...
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Ans. is 'b' i.e., T-cell blockade
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Recommended Dietary Allowance (RDA): Is a level of intake corresponding to Mean + 2 Standard Deviation, which covers requirement of 97.5 % of population RDA is safe level of intake which is likely to be inadequate in not more than 2.5 % population RDA 'safe level approach' is NOT USED FOR ENERGY since excess energy in...
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D i.e. Alpha linolenic acidAlpha linolenic acid belongs to W3 seriesQ. Rest others belong to W6 series.Carbon atoms are numbered from the carboxyl carbon (carbon no. 1). The carbon atoms adjacent to carboxyl carbon are also called. a, 13, Y respectively. The terminal methyl carbon is K/as W or n- carbonW3 Family ,MILW6...
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B i.e. Sebaceous cyst Also known as meibomian or tarsal cyst is chronic, sterile lipogranulomatous inflammation of meibomian gland Predisposing factors Clinical features Course & Complication Treatment Patient with acne - Gradually enlarging - Resolve spontaneously - In small, soft & recent chalazion conservative rosac...
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Russia is the first country to socialize medicine completely and to give all its citizens a constitutional right to health services. Ref: Park, 21st Edition, Page 9.
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Ans. Nihilistic delusion
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HCG
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Enthesopathy Enthesopathy is any abnormality of the site where the tendons and ligaments join the bone. Abnormalities that can occur include inflammation (enthesitis) and calcification. Important causes are:- Ankylosing spondylitis       Plantar fascitis Other seronegative spondyloarthropaties    Golfer's elbow Reit...
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a. Kawasaki disease(Ref: Nelson's 20/e p 1221-1223, Ghai 8/e p 631-635)Coronary artery aneurysm is an important complication of Kawasaki disease
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Traditionally considered a hyperextension/distraction injury from placement of the noose under the angle of the jaw, hangman's fractures also may occur with hyperextension/ compression, as with diving accidents, or hyperflexion. The injury is defined by bilateral C2 pars interaicularis fractures. The pars interaiculari...
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Ans. (d) Macrocytic anaemiaRef. Robbins pathology 9th ed. /638* Thalassemia major presents before 1 yr of age with severe anemia which necessitates packed RBC transfusions every 2-3 months. The child is said to be transfusion dependent as survival is decided by RBC being transfused.* The ineffective erythropoiesis in b...
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A i.e. Toes & fingers
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Blockage of cutaneous lymphatic vessels results in edema of the skin surrounding the hair follicles, leading to an appearance like an orange peel (peau d'orange). Shortening of the suspensory ligaments leads to dimpling of the overlying skin, not peau d'orange. Contraction of retinacula cutis results in retraction and ...
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Ref: Harrison's Principles of Internal Medicine, 18th edition, page 3148Explanation:Familial hypercholesterolemia (FH):Homozygous FH is AD.one of the common single-gene disordersElevated LDL (500- lOOOmg/dL), normal TGCutaneous xanthomasPremature coronary artery diseaseEarly death in childrenHeterozygous FH . i in 500 ...
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The primary histological differences in the three regions of the small intestine are the presence of : Peyer patches in the lamina propria of the ileum Brunner glands in the submucosa of the duodenum. Goblet cells are present throughout the small intestine. Lacteals are the Lymphatic vessels of small intestine which ab...
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Ans. C: Odd's ratio can be calculated Coho study is often undeaken to obtain evidence to try to refute the existence of a suspected association between cause and effect. Crucially, the coho is identified before the appearance of the disease under investigation. The study groups, so defined, are observed over a period o...
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Patient-controlled analgesia (PCA) is now in widespread use for the management of breakthrough pain. With PCA, the patient controls a parenteral usually intravenous infusion device by pressing a button to deliver a preprogrammed dose of the desired opioid analgesic. Has better pain control using less opioid. REF: Katzu...
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Ectopic ureter A ureter that drains outside the bladder is referred to as an ectopic ureter. Ectopic ureter usually drains the upper pole of a duplex collecting system (two ureter → duplication of ureter). It is more common in girls. The opening of ectopic ureter differs in female and males - I) Female Urethra at bl...
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Ref Robbins 7/e p197 ;9/e p210 , macrophages and B lymphocytes is also the answer Professional antigen presenting cells(APCs) are immune cells that specialize in presentingan antigen to a T-cell. The main types of professional APCs are dendritic cells (DC), macrophages, and Bcells, Langerhans cells
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1. In P. falciparum infection, the later stages of erythrocytic cycle occur in the capillaries of brain and internal organs. Hence only ring forms are found in peripheral blood by microscopic examination but not late trophozoites and Schizonts. 2. In PBS, all asexual erythrocytic stages, as well as gametocytes can be s...
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Ans. is 'a' i.e., Coconut oil
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IgA nephropathy or Berger's disease: immune complex-mediated glomerulonephritis defined by the presence of diffuse mesangial IgA deposits often associated with mesangial hypercellularity. Male preponderance, peak incidence in the second and third decades of life.Clinical and laboratory findings: Two most common present...
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Elevation of testis reduces the pain in epididymo-orchiditis and makes it's worse in torsion of testis. Ref: Radiology Illustrated: Uroradiology By Seung Hyup Kim, 2012, page 910; Bailey and Love's Sho Practice of Surgery, 23rd Edition, Pages 1040, 1380.
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Ans. is "a' i.e., Acts as PPAR gamma agonist [Ref KDT 7*/ep. 276\Rosiglitazoneo It is oral antidiabetic drugo They are selective agonists for nuclear peroxisome proliferator activator receptor gamma (PPAR gamma) expressed in the fat and muscle cells.o It enhances transcription of several insulin responsive genes,o Reve...
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Left atrial enlargement presents radiologically with elevation of left main bronchus which is the earlier feature ,splaying or widening of carina ,indentation and displacement of oesophagus posteriorly , double contour / shadow / density or double right hea border and prominent left atrial appendage.
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Maternal moality is not seen in Vasa Pre whereas fetal moality is seen. Vasa Pre: The unsuppoed umbilical blood vessels in Velamentous placenta lie below the presenting pa and run across cervical os. The vessels are torn either spontaneously or during rupture of membranes. Color Doppler is helpful in antenatal diagnosi...
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The lower ribs flare out,the subcostal angle increases from 68deg to 103deg,the transverse diameter of the chest increases by 2 cm and the diaphragm rises by about 4 cm in pregnancy. Refer page no 80 of text book of obsteics,sheila balakrishnan,2 nd edition.
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In a pattern of lipid deposition seen with prolonged moderate hypoxia,such as that produced by profound anemia,there is intracellular deposits of fat,which create grossly apparent bands of yellowed myocardium alternating with bands of darker,red brown,uninvolved myocardiun. (ref Robbins 8/e p34)
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In obstruction of the CBD due to a stone,distension of gallbladder seldom occurs.The organ is usually shrivelled.In obstruction from other causes ,distension of gallbladder is common by comparison. Reference:Bailey & Love's sho practise of surgery,25th edition,page no:1125
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Ans. a. 100Bicarbonate deficit can be calculated as follows:1st method by formula:HCO3- deficit=0.5xbody weight in kgx(24-HCO3- )Half of the calculated deficit should be administered within the first 3-4 hours to avoid overcorrection and volume overload.2nd method: In general, severe acidosis (pH<7.10) warrants the IV ...
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Answwr is option 1 Abstract Malignancy is associated with a "hypercoagulable" state and a high risk for thrombohemorrhagic complications. Clinical complications may range from localized thrombosis to bleeding of varying degrees of severity because of disseminated intravascular coagulation (DIC). Life-threatening bleedi...
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Reinforced Anchorage   It involves reinforcing the anchorage or resistance area either by adding more resistance units or by the use of various adjuncts. A simple way of reinforcing anchorage is to band the second molars. Various other ways include, the use of T.P.A., Nance holding arch, lower lingual arch. Tissue anc...
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The synopsis of forensic medicine & toxicology ; Dr k.s narayan reddy ; 28th edition ;pg.no 131 A di collar is seen in firearm entry wound ,it is seen as narrow ring of skin ,lining the defect & is sharply outlined . This results from the removal of substances from the bullet as it passes through the skin ,i.e bullet l...
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Ans. is 'a' i.e., Can be washed away Antemortem vs postmortem woundFeatureAntemortal woundPost Mortem WoundHaemorrhage* Arterial* Blood clotted and the clot is# Laminated# Firmly adherent to the lining of endothelium# Firm, Rubbery and Variegated* Venous* Blood usually not clotted and if clot it is# Non laminated# Weak...
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Homer's syndrome is due to interruption of sympathetic fibres and therefore causes meiosis (constriction of pupil). Nasal stuffiness is due to dilatation of blood vessels.
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Ans. is a, i.e. TorsionRef: Shaw 15th/ed, p382Complications of Ovarian tumor (TRIP):T Torsion* Most common complication* Seen in 12% cases* Most common in benign tumors* Most common tumor to undergo torsion is dermoid cyst. - Ref: Jeffcoate 7th/ed, p548R Rupture* Which can be traumatic or spontaneous.I Infection* Rare ...
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ANSWER: (B) ObturatorREF: Danforth s Obstetrics and Gynaecology 10th ed P-4S7Nerves commonly injured in obstetrics and their etiologiesNerveEtiologyFemoral (L2-L4)Hyperflexion of hips with traction or compression injury of nerve, prolonged lithotomy position with kinking of poupart's ligament, midforceps delivery, retr...
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Drug-induced lupus erythematosus A lupus like syndrome may develop in patients receiving a variety of drugs, Procainamide and hydralazine are the most common offenders, Most patients do not have symptoms of lupus erythematosus. Anti-ds DNA antibody is rare There is an extremely high frequency of antihistone antibodie...
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- triage consists of rapidly classifying the injured on the basis of severity of their injuries and the likelihood of their survival with prompt medical intervention. - black colour triage signals dead or moribund patients. Reference: Park's textbook of preventive and social medicine, 23rd edition, pg no: 796 <\p>
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NADPH does not produce ATP in RBCs.NADPHSources of NADPH:HMP shunt enzymes:- Glucose-6-phosphate dehydrogenase- 6-phospho gluconate dehydrogenaseCytoplasmic isocitrate dehydrogenasesMalic enzyme (decarboxylating malate dehydrogenase)NADPH is required for:Reductive biosynthesis of all lipids including fatty acid synthes...
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Ref: Miller Textbook of Anaesthesia. 6th editionExplanation:Malignant HyperthermiaIt is a clinical syndrome observed during GA associated with rapidly increasing temperature of >ldegree/5 minEtiologyIt is due to the abnormality of Ryanodine receptor which is a calcium releasing channel of sarcoplasmic reticulum.The abn...
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3rd heart sound is due to passive ventricular filling which occurs in early rapid filling phase of ventricular diastole.
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Sideropenic dysphagia or plummer vinson syndrome has post cricoid webs. Triad is IDA, chelitis and koilonychia.
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Atherosclerosis is a slowly progressive disease of large to medium-sized muscular aeries and large elastic aeries characterised by elevated focal intimal fibrofattyPlaques. Principal larger vessels affected are the abdominal aoa, descending thoracic aoa, internal carotid aeries and medium to smaller sized vessels affec...
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schizophrenia: widespread slow activity, dysrhythmia, spikes, and spike-wave complexes) generally have been regarded as nonspecific. mood disorders : depression: an increase of alpha and/or beta activity left frontal regions in depressed patients. ( decreased left frontal activation) manic episode: Less alpha power and...
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(Ref: Katzung, 14th ed. pg. 59; KDT, 6th ed. pg. 27)Enzyme induction involves microsomal enzyme in liver as well as in other organ.It increases the rate of metabolism 2 - 4 fold. Therefore, effect of drug decreases.Enzyme inhibitors also involves microsomal enzyme.It inhibits the microsomal enzyme, which decreases drug...
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Arachidonic acid pathway
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Sputum or bronchoalveolar lavage specimen findings - Curschmann spirals (extrusion of mucus plugs from subepithelial mucous gland ducts or bronchioles). Numerous eosinophils and Charcot-Leyden crystals; the latter are composed of an eosinophil protein called galectin-10. Creola bodies The other characteristic histologi...
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Cocaine in the periphery blocks uptake of NA and adrenaline into adrenergic nerve endings,resulting in higher concentration of the transmitter around the receptors leading to sympathomimetic effect thats is vasoconstriction , tachycardia,rise in BP , mydriasis. From KD Tripati 7th edition Page no 365
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Ans. b. Tracheal stenosis "Topical Mitomycin C is the drug of choice used to aid the treatment of laryngeal stenosis. Topical Mitomycin C can inhibit fibroblast activity and restenosis."
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Cholesterol * Increase in cholesterol conc. - less fluid on outer surface, more fluid on inner surface Effect of cholesterol on fluidity is different with different temperature. At temperature below Tm - cholesterol increases fluidity At temperature above Tm - cholesterol decreases fluidity ref : guyton and hall
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E. coli 0157:H7 serotype belongs to EHEC. EHEC Highly virulent serotype. Has low infectious dose (10-100 bacilli). Produce a verotoxin similar to Shiga toxin. Causes hemorrhagic colitis, HUS. Principal cause of acute kidney failure in children.
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Route is Subcutaneous.
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Immunoglobulin A deficiency is the commonest immunodeficiency syndrome, occurring in 1 in 600 patients. It is especially common in Caucasians. The most well-defined aspect of the syndrome is the development of severe allergic reactions to the IgA contained in transfused blood. Patients probably have an increased incide...
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Ans-D i.e., Intracavity brachytherapy followed by external beam radiotherapy Stage 1IA * Invasion limited to the measured stromal invasion with the maximum depth of 5mm and not wider than 7 mm IA1 * Invasion of stroma not greater than 3 mm in depth and no wider than 7mmIA2 * Measured invasion of stroma greater than 3mm...
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Amongst the given options al antitrypsin deficiency is the best answer because neonatal hepatitis and extrahepatic biliary atresia are not there.
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