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wiki_8900_chunk_0 | Mir-636 microRNA precursor family | In molecular biology mir-636 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8901_chunk_0 | Mir-661 microRNA precursor family | In molecular biology mir-661 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8902_chunk_0 | Mir-663 microRNA precursor family | In molecular biology mir-663 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8903_chunk_0 | Mir-71 microRNA precursor family | In molecular biology mir-71 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8904_chunk_0 | Mir-711 microRNA precursor family | In molecular biology mir-711 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8905_chunk_0 | Mir-84 microRNA precursor family | In molecular biology mir-84 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8906_chunk_0 | Mir-885 microRNA precursor family | In molecular biology mir-885 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8907_chunk_0 | Short linear motif | In molecular biology short linear motifs (SLiMs), linear motifs or minimotifs are short stretches of protein sequence that mediate protein–protein interaction.The first definition was given by Tim Hunt: "The sequences of many proteins contain short, conserved motifs that are involved in recognition and targeting activi... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8908_chunk_0 | B-box zinc finger | In molecular biology the B-box-type zinc finger domain is a short protein domain of around 40 amino acid residues in length. B-box zinc fingers can be divided into two groups, where types 1 and 2 B-box domains differ in their consensus sequence and in the spacing of the 7-8 zinc-binding residues. Several proteins conta... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8909_chunk_0 | BED zinc finger | In molecular biology the BED-type zinc finger domain is a protein domain which was named after the Drosophila proteins BEAF and DREF, is found in one or more copies in cellular regulatory factors and transposases from plants, animals and fungi. The BED finger is an about 50 to 60 amino acid residues domain that contain... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8910_chunk_0 | BMC domain | In molecular biology the Bacterial Microcompartment (BMC) domain is a protein domain found in a variety of shell proteins, including CsoS1A, CsoS1B and CsoS1C of Thiobacillus neapolitanus (Halothiobacillus neapolitanus) and their orthologs from other bacteria. These shell proteins form the polyhedral structure of the c... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8911_chunk_0 | DHHC domain | In molecular biology the DHHC domain is a protein domain that acts as an enzyme, which adds a palmitoyl chemical group to proteins in order to anchor them to cell membranes. The DHHC domain was discovered in 1999 and named after a conserved sequence motif found in its protein sequence. Roth and colleagues showed that t... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8912_chunk_0 | DHHC domain | In mammals twenty three members of this family have been identified and their substrate specificities investigated. Some members of the family such as ZDHHC3 and ZDHHC7 enhance palmitoylation of proteins such as PSD-95, SNAP-25, GAP43, Gαs. Others such as ZDHHC9 showed specificity only toward the H-Ras protein. However... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8913_chunk_0 | DM domain | In molecular biology the DM domain is a protein domain first discovered in the doublesex proteins of Drosophila melanogaster and is also seen in C. elegans and mammalian proteins. In D. melanogaster the doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8914_chunk_0 | FGGY carbohydrate kinase family | In molecular biology the FGGY carbohydrate kinase family is a family of evolutionarily related carbohydrate kinase enzymes. These enzymes include L-fuculokinase EC 2.7.1.51 (gene fucK); gluconokinase EC 2.7.1.12 (gene gntK); glycerol kinase EC 2.7.1.30 (gene glpK); xylulokinase EC 2.7.1.17 (gene xylB); D-ribulose kinas... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8915_chunk_0 | FYVE domain | In molecular biology the FYVE zinc finger domain is named after the four cysteine-rich proteins: Fab 1 (yeast orthologue of PIKfyve), YOTB, Vac 1 (vesicle transport protein), and EEA1, in which it has been found. FYVE domains bind phosphatidylinositol 3-phosphate, in a way dependent on its metal ion coordination and ba... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8916_chunk_0 | L-type lectin domain | In molecular biology the L-like lectin domain is a protein domain found in lectins which are similar to the leguminous plant lectins. Lectins are structurally diverse proteins that bind to specific carbohydrates. This family includes the VIP36 and ERGIC-53 lectins. Although proteins containing this domain were original... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8917_chunk_0 | LysM domain | In molecular biology the LysM domain is a protein domain found in a wide variety of extracellular proteins and receptors. The LysM domain is named after the Lysin Motif which was the original name given to the sequence motif identified in bacterial proteins. The region was originally identified as a C-terminal repeat f... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8918_chunk_0 | LysM domain | LysM domains are also found in plant receptors, including NFP, the receptor for Nod factor which is necessary for the root nodule symbiosis between legumes and symbiotic bacteria. The LysM domain is typically between 44 and 65 amino acid residues in length. The structure of the LysM domain showed that it is composed of... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8919_chunk_0 | MIZ zinc finger | In molecular biology the MIZ-type zinc finger domain is a zinc finger-containing protein with homology to the yeast protein, Nfi-1. Miz1 is a sequence specific DNA binding protein that can function as a positive-acting transcription factor. Miz1 binds to the homeobox protein Msx2, enhancing the specific DNA-binding abi... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8920_chunk_0 | MYND zinc finger | In molecular biology the MYND-type zinc finger domain is a conserved protein domain. The MYND domain (myeloid, Nervy, and DEAF-1) is present in a large group of proteins that includes RP-8 (PDCD2), Nervy, and predicted proteins from Drosophila, mammals, Caenorhabditis elegans, yeast, and plants. The MYND domain consist... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8921_chunk_0 | MYND zinc finger | Mutating conserved cysteine residues in the DEAF-1 MYND domain does not abolish DNA binding, which suggests that the MYND domain might be involved in protein-protein interactions. Indeed, the MYND domain of ETO/MTG8 interacts directly with the N-CoR and SMRT co-repressors. Aberrant recruitment of co-repressor complexes... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8922_chunk_0 | MYND zinc finger | ETO has been shown to be a co-repressor recruited by the promyelocytic leukemia zinc finger (PLZF) protein. A divergent MYND domain present in the adenovirus E1A binding protein BS69 was also shown to interact with N-CoR and mediate transcriptional repression. The current evidence suggests that the MYND motif in mammal... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8923_chunk_0 | PIN domain | In molecular biology the PIN domain is a protein domain that is about 130 amino acids in length. PIN domains function as nuclease enzymes that cleave single stranded RNA in a sequence- or structure-dependent manner.PIN domains contain four nearly invariant acidic residues. Crystal structures show these residues cluster... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8924_chunk_0 | PIN domain | The majority of PIN-domain proteins found in prokaryotes are the toxic components of toxin-antitoxin operons. These loci provide a control mechanism that helps free-living prokaryotes cope with nutritional stress. == References == | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8925_chunk_0 | PLAT domain | In molecular biology the PLAT domain is a protein domain that is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain binds to procolipase Pfam... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8926_chunk_0 | SPR domain | In molecular biology the SPR domain is a protein domain found in the Sprouty (Spry) and Spred (Sprouty related EVH1 domain) proteins. These have been identified as inhibitors of the Ras/mitogen-activated protein kinase (MAPK) cascade, a pathway crucial for developmental processes initiated by activation of various rece... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8927_chunk_0 | SeqA protein | In molecular biology the SeqA protein is found in bacteria and archaea. The function of this protein is highly important in DNA replication. The protein negatively regulates the initiation of DNA replication at the origin of replication, in Escherichia coli, OriC. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8928_chunk_0 | SeqA protein | Additionally the protein plays a further role in sequestration. The importance of this protein is vital, without its help in DNA replication, cell division and other crucial processes could not occur. This protein domain is thought to be part of a much larger protein complex which includes other proteins such as SeqB. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8929_chunk_0 | ZZ zinc finger | In molecular biology the ZZ-type zinc finger domain is a type of protein domain that was named because of its ability to bind two zinc ions. These domains contain 4-6 Cys residues that participate in zinc binding (plus additional Ser/His residues), including a Cys-X2-Cys motif found in other zinc finger domains. These ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8930_chunk_0 | ZZ zinc finger | In addition, the Cys-rich domains of dystrophin, utrophin and an 87kDa post-synaptic protein contain a ZZ-type zinc finger with high sequence identity to P300/CBP ZZ-type zinc fingers. In dystrophin and utrophin, the ZZ-type zinc finger lies between a WW domain (flanked by and EF hand) and the C-terminal coiled-coil do... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8931_chunk_0 | Fructosamine kinase family | In molecular biology the fructosamine kinase family is a family of enzymes. This family includes eukaryotic fructosamine-3-kinase enzymes which may initiate a process leading to the deglycation of fructoselysine and of glycated proteins and in the phosphorylation of 1-deoxy-1-morpholinofructose, fructoselysine, fructos... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8932_chunk_0 | Fructosamine kinase family | Ketosamine-3-kinases (KT3K) catalyse the phosphorylation of the ketosamine moiety of glycated proteins. The instability of a phosphorylated ketosamine leads to its degradation, and KT3K is thus thought to be involved in protein repair.The function of the prokaryotic members of this group has not been established. Howev... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8933_chunk_0 | Nematode Her-1 | In molecular biology the nematode Her-1 protein is a protein which adopts an all-helical structure with two subdomains: amino acids 19-80 comprise a left-handed three-helix bundle with an overhand connection between the second and third helices, whilst amino acids 81-164 comprise a left-handed anti-parallel four-helix ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8934_chunk_0 | Orange carotenoid N-terminal domain | In molecular biology the orange carotenoid N-terminal domain is a protein domain found predominantly at the N-terminus of the Orange carotenoid protein (OCP), and is involved in non-covalent binding of a carotenoid chromophore. It is unique for being present in soluble proteins, whereas the vast majority of domains cap... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8935_chunk_0 | Orange carotenoid N-terminal domain | The domain adopts an alpha-helical structure consisting of two four-helix bundles.Orange carotenoid-binding proteins (OCP) were first identified in cyanobacterial species, where they occur associated with phycobilisome in the cellular thylakoid membrane. These proteins function in photoprotection, and are essential for... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8936_chunk_0 | Orange carotenoid N-terminal domain | The N-terminal domain of OCP is usually accompanied by a C-terminal domain which belongs to the NTF2 superfamily and helps bind the carotenoid. OCP can be proteolytically cleaved into a red form (RCP), which lacks 15 residues from the N-terminus and approximately 150 residues from the C terminus. This domain is implica... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8937_chunk_0 | SSI protease inhibitor | In molecular biology the protein SSI is a Subtilisin inhibitor-like which stands for Streptomyces subtilisin inhibitor. This is a protease inhibitor. These are often synthesised as part of a larger precursor protein, either as a prepropeptide. The function of this protein domain is to prevent access of the substrate to... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8938_chunk_0 | S-Adenosylmethionine synthetase enzyme | In molecular biology the protein domain S-adenosylmethionine synthetase N terminal domain is found at the N-terminal of the enzyme. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8939_chunk_0 | Siah interacting protein N-terminal domain | In molecular biology the protein domain, Siah interacting protein N-terminal domain is found at the N-terminal of the protein, Siah interacting protein (SIP). It has a helical hairpin structure with a hydrophobic core which is further stabilised by an arrangement of side chains contributed by the two amphipathic helice... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8940_chunk_0 | SprX small RNA | In molecular biology the small pathogenicity island RNA X (alias RsaOR) gene is a bacterial non-coding RNA. It was discovered in a large-scale analysis of Staphylococcus aureus. SprX was shown to influence antibiotic resistance of the bacteria to Vancomycin and Teicoplanin glycopeptides, which are used to treat MRSA in... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8941_chunk_0 | MamL-1 domain | In molecular biology there are a number of neurogenic proteins referred to as mastermind-like proteins (MAMLs) of which this domain is the N-terminal region. Mastermind-like proteins act as critical transcriptional co-activators for Notch signaling.The N-terminal domain of MAML proteins, MAML1, MAML2, MAML3, is a polyp... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8942_chunk_0 | MamL-1 domain | The C-terminal region is required for transcriptional activation. Notch receptors are cleaved upon ligand engagement and the intracellular domain of Notch shuttles to the nucleus. MAMLs form a functional DNA-binding complex with the cleaved Notch receptor and the transcription factor CSL, thereby regulating transcripti... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8943_chunk_0 | MamL-1 domain | MAML proteins may also play roles as key transcriptional co-activators in other signal transduction pathways as well, including: muscle differentiation and myopathies (MEF2C), tumour suppressor pathway (p53) and colon carcinoma survival (beta-catenin). MAML proteins could mediate cross-talk among the various signaling ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8944_chunk_0 | UbiD protein domain | In molecular biology this protein domain, refers to UbiD, which is found in prokaryotes, archaea and fungi, with two members in Archaeoglobus fulgidus. They are related to UbiD, a 3-octaprenyl-4-hydroxybenzoate carboxy-lyase from Escherichia coli that is involved in ubiquinone biosynthesis. The member from Helicobacter... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8945_chunk_0 | Formylglycine-generating enzyme | In molecular biology, "formylglycine-generating enzyme" (sometimes annotated as formylglycine-generating sulfatase enzyme) is the name of the FGE protein domain, whether or not the protein is catalytically active. Both prokaryotic and eukaryotic homologs of FGE possess highly conserved active sites — including the cata... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8946_chunk_0 | 2'-5'-oligoadenylate synthase | In molecular biology, 2'-5'-oligoadenylate synthetase (2-5A synthetase) is an enzyme (EC 2.7.7.84) that reacts to interferon signal. It is an antiviral enzyme that counteracts viral attack by degrading RNAs, both viral and host. The enzyme uses ATP in 2'-specific nucleotidyl transfer reactions to synthesize 2'-5'-oligo... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8947_chunk_0 | ADF-H domain | In molecular biology, ADF-H domain (actin-depolymerising factor homology domain) is an approximately 150 amino acid motif that is present in three phylogenetically distinct classes of eukaryotic actin-binding proteins. ADF/cofilins, which include ADF, cofilin, destrin, actophorin, coactosin, depactin and glia maturatio... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8948_chunk_0 | ADF-H domain | ADF/cofilins bind ADP-actin with higher affinity than ATP-actin and inhibit the spontaneous nucleotide exchange on actin monomers Twinfilins, which are actin monomer-binding proteins that are composed of two ADF-H domains Abp1/Drebrins, which are relatively large proteins composed of an N-terminal ADF-H domain followed... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8949_chunk_0 | ATP10 protein | In molecular biology, ATP10 protein (mitochondrial ATPase complex subunit ATP10) is an ATP synthase assembly factor. It is essential for the assembly of the mitochondrial F1-F0 complex. A yeast nuclear gene (ATP10) encodes a product that is essential for the assembly of a functional mitochondrial ATPase complex. Mutati... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8950_chunk_0 | BAG domain | In molecular biology, BAG domains are protein domains found in proteins which are modulators of chaperone activity, they bind to HSP70/HSC70 proteins and promote substrate release. The proteins have anti-apoptotic activity and increase the anti-cell death function of BCL-2 induced by various stimuli. BAG-1 binds to the... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8951_chunk_0 | BAG domain | The binding of Hsp70 to BAG-1 diminishes Raf-1 signalling and inhibits subsequent events, such as DNA synthesis, as well as arrests the cell cycle. BAG-1 has been suggested to function as a molecular switch that encourages cells to proliferate in normal conditions but become quiescent under a stressful environment .BAG... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8952_chunk_0 | BAG domain | The first and second helices interact with the serine/threonine kinase Raf-1 and the second and third helices are the sites of the BAG domain interaction with the ATPase domain of Hsc70/Hsp70. Binding of the BAG domain to the ATPase domain is mediated by both electrostatic and hydrophobic interactions in BAG-1 and is e... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8953_chunk_0 | BAR domain | In molecular biology, BAR domains are highly conserved protein dimerisation domains that occur in many proteins involved in membrane dynamics in a cell. The BAR domain is banana-shaped and binds to membrane via its concave face. It is capable of sensing membrane curvature by binding preferentially to curved membranes. ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8954_chunk_0 | DNA beta-glucosyltransferase | In molecular biology, Bacteriophage T4 beta-glucosyltransferase refers to a protein domain found in a virus of Escherichia coli named bacteriophage T4. Members of this family are enzymes encoded by bacteriophage T4, which modify DNA by transferring glucose from uridine diphosphoglucose to 5-hydroxymethyl cytosine bases... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8955_chunk_0 | Beta-ketoacyl-ACP synthase | In molecular biology, Beta-ketoacyl-ACP synthase EC 2.3.1.41, is an enzyme involved in fatty acid synthesis. It typically uses malonyl-CoA as a carbon source to elongate ACP-bound acyl species, resulting in the formation of ACP-bound β-ketoacyl species such as acetoacetyl-ACP. Beta-ketoacyl-ACP synthase is a highly con... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8956_chunk_0 | Beta-ketoacyl-ACP synthase | Beta-ketoacyl-ACP synthases I and II only catalyze acyl-ACP reactions with malonyl ACP. Synthases I and II are capable of producing long-chain acyl-ACPs. Both are efficient up to acyl-ACPs with a 14 carbon chain, at which point synthase II is the more efficient choice for further carbon additions. Type I FAS catalyzes ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8957_chunk_0 | BpuJI | In molecular biology, BpuJI is a type II restriction endonuclease which recognises the asymmetric sequence 5'-CCCGT and cuts at multiple sites in the surrounding area of the target sequence. The BpuJI protein consists of two distinct modules; an N-terminal DNA recognition domain, and a C-terminal dimerisation and catal... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8958_chunk_0 | Small nucleolar RNA CD11 | In molecular biology, CD11 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8959_chunk_0 | Integrin beta 2 | In molecular biology, CD18 (Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. Upon binding with one of a number of alpha chains, CD18 is capable of forming multiple heterodimers, which play significant roles in cellular adhesion and cell surface signaling, as well as ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8960_chunk_0 | CD4 | In molecular biology, CD4 (cluster of differentiation 4) is a glycoprotein that serves as a co-receptor for the T-cell receptor (TCR). CD4 is found on the surface of immune cells such as T helper cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 an... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8961_chunk_0 | CD4 | They are often referred to as CD4 cells, T-helper cells or T4 cells. They are called helper cells because one of their main roles is to send signals to other types of immune cells, including CD8 killer cells, which then destroy the infectious particle. If CD4 cells become depleted, for example in untreated HIV infectio... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8962_chunk_0 | Caf1 capsule antigen | In molecular biology, Caf1 capsule antigen proteins are a family of the F1 capsule antigens Caf1 synthesised by Yersinia bacteria. They adopt a structure consisting of a seven strands arranged in two beta-sheets, in a Greek-key topology, and mediate targeting of the bacterium to sites of infection. == References == | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8963_chunk_0 | Circular RNA databases and resources | In molecular biology, Circular RNAs (circRNAs) refer to a class of circular RNA molecules found across all kingdoms of life. Studies in 2013 have suggested that circRNAs play important regulatory roles in miRNA activity. Researchers found that CDR1as circRNA acts as a miR-7 super-sponge that contains about 70 target si... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8964_chunk_0 | Circular RNA databases and resources | About-mentioned examples suggesting that miRNA sponge effects achieved by circRNA formation may be a general phenomenon. As miR-7 modulates the expression of several oncogenes, ciRS-7/miR-7 interactions may play an important roles in cancer-related pathways. circRNA has also been shown in viral infection where it seque... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8965_chunk_0 | D-stereospecific aminopeptidase | In molecular biology, D-stereospecific aminopeptidase (D-aminopeptidase) EC 3.4.11.19 is an enzyme which catalyses the release of an N-terminal D-amino acid from a peptide, Xaa-|-Yaa-, in which Xaa is preferably D-Ala, D-Ser or D-Thr. D-amino acid amides and methyl esters also are hydrolyzed, as is glycine amide. It is... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8966_chunk_0 | D-stereospecific aminopeptidase | It is connected to domain A, the catalytic domain, by an eight-residue sequence, and also interacts with both domains A and C via non-covalent bonds. Domain B probably functions in maintaining domain C in a good position to interact with the catalytic domain. Domain C is organised to form a beta barrel made up of eight... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8967_chunk_0 | DCTN6 | In molecular biology, DCTN6 is that subunit of the dynactin protein complex that is encoded by the p27 gene. Dynactin is the essential component for microtubule-based cytoplasmic dynein motor activity in intracellular transport of a variety of cargoes and organelles. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8968_chunk_0 | Replication Fork | In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. DNA replication occurs in all living organisms acting as the most essential part of biological inheritance. This is essential for cell division during growth and repair of damaged t... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8969_chunk_0 | Replication Fork | DNA is made up of a double helix of two complementary strands. The double helix describes the appearance of a double-stranded DNA which is thus composed of two linear strands that run opposite to each other and twist together to form. During replication, these strands are separated. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8970_chunk_0 | Replication Fork | Each strand of the original DNA molecule then serves as a template for the production of its counterpart, a process referred to as semiconservative replication. As a result of semi-conservative replication, the new helix will be composed of an original DNA strand as well as a newly synthesized strand. Cellular proofrea... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8971_chunk_0 | Replication Fork | Unwinding of DNA at the origin and synthesis of new strands, accommodated by an enzyme known as helicase, results in replication forks growing bi-directionally from the origin. A number of proteins are associated with the replication fork to help in the initiation and continuation of DNA synthesis. Most prominently, DN... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8972_chunk_0 | Replication Fork | DNA replication occurs during the S-stage of interphase. DNA replication (DNA amplification) can also be performed in vitro (artificially, outside a cell). | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8973_chunk_0 | Replication Fork | DNA polymerases isolated from cells and artificial DNA primers can be used to start DNA synthesis at known sequences in a template DNA molecule. Polymerase chain reaction (PCR), ligase chain reaction (LCR), and transcription-mediated amplification (TMA) are examples. In March 2021, researchers reported evidence suggest... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8974_chunk_0 | B5 protein domain | In molecular biology, Domain B5 is found in phenylalanine-tRNA synthetase beta subunits. This domain has been shown to bind DNA through a winged helix-turn-helix motif. Phenylalanine-tRNA synthetase may influence common cellular processes via DNA binding, in addition to its aminoacylation function. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8975_chunk_0 | Duffy binding proteins | In molecular biology, Duffy binding proteins are found in Plasmodium. Plasmodium vivax and Plasmodium knowlesi merozoites invade Homo sapiens erythrocytes that express Duffy blood group surface determinants. The Duffy receptor family is localised in micronemes, an organelle found in all organisms of the phylum Apicompl... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8976_chunk_0 | Endoribonuclease XendoU | In molecular biology, Endoribonuclease XendoU refers to a protein domain. This particular entry represents endoribonucleases involved in RNA biosynthesis which has been named XendoU in Xenopus laevis (African clawed frog). This protein domain belongs to a family of evolutionarily related proteins. XendoU is a U-specifi... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8977_chunk_0 | ERH (gene) | In molecular biology, Enhancer of rudimentary homolog is a protein that in humans is encoded by the ERH gene.The Drosophila protein enhancer of rudimentary protein is a small protein of 104 amino acids. It has been found to be an enhancer of the rudimentary gene, involved in pyrimidine biosynthesis.From an evolutionary... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8978_chunk_0 | FMR1-AS1 gene | In molecular biology, FMR1 antisense RNA 1 (FMR1-AS1), also known as ASFMR1 or FMR4, is a long non-coding RNA. The FMR1-AS1 gene overlaps, and is antisense to, the CGG repeat region of the FMR1 gene. Its expression is upregulated in fragile X syndrome premutation carriers, and silenced in patients with fragile X syndro... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8979_chunk_0 | GATA zinc finger | In molecular biology, GATA zinc fingers are zinc-containing domains found in a number of transcription factors (including erythroid-specific transcription factor and nitrogen regulatory proteins). Some members of this class of zinc fingers specifically bind the DNA sequence (A/T)GATA(A/G) in the regulatory regions of g... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8980_chunk_0 | GATA zinc finger | The N-terminal part, which includes the helix, is similar in structure, but not sequence, to the N-terminal zinc module of the glucocorticoid receptor DNA-binding domain. The helix and the loop connecting the 2 beta-sheets interact with the major groove of the DNA, while the C-terminal tail wraps around into the minor ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8981_chunk_0 | GATA zinc finger | It is also worth noting that many GATA-type Znfs (such as those found in the proteins GATAD2B and MTA1) have not been experimentally demonstrated to be DNA-binding domains. Furthermore, several GATA-type Znfs have been demonstrated to act as protein-recognition domains. For example, the N-terminal Znf of GATA1 binds sp... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8982_chunk_0 | Glycoside hydrolase family 10 | In molecular biology, Glycoside hydrolase family 10 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside h... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8983_chunk_0 | Glycoside hydrolase family 11 | In molecular biology, Glycoside hydrolase family 11 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside h... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8984_chunk_0 | Glycoside hydrolase family 12 | In molecular biology, Glycoside hydrolase family 12 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside h... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8985_chunk_0 | Glycoside hydrolase family 14 | In molecular biology, Glycoside hydrolase family 14 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside h... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8986_chunk_0 | Glycoside hydrolase family 14 | A Glu residue has been proposed as a catalytic residue, but it is not known if it is the nucleophile or the proton donor. Beta-amylase is an enzyme that hydrolyzes 1,4-alpha-glucosidic linkages in starch-type polysaccharide substrates so as to remove successive maltose units from the non-reducing ends of the chains. Be... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8987_chunk_0 | Glycoside hydrolase family 14 | The 3D structure of a complex of soybean beta-amylase with an inhibitor (alpha-cyclodextrin) has been determined to 3.0A resolution by X-ray diffraction. The enzyme folds into large and small domains: the large domain has a (beta alpha)8 super-secondary structural core, while the smaller is formed from two long loops e... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8988_chunk_0 | Glycoside hydrolase family 16 | In molecular biology, Glycoside hydrolase family 16 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside h... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8989_chunk_0 | Glycoside hydrolase family 17 | In molecular biology, Glycoside hydrolase family 17 is a family of glycoside hydrolases. It folds into a TIM barrel. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classific... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8990_chunk_0 | Glycoside hydrolase family 18 | In molecular biology, Glycoside hydrolase family 18 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside h... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8991_chunk_0 | Glycoside hydrolase family 19 | In molecular biology, Glycoside hydrolase family 19 is a family of glycoside hydrolases. Glycoside hydrolases EC 3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside h... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8992_chunk_0 | Glycoside hydrolase family 19 | Chitinases of family 19 (also known as classes IA or I and IB or II) are enzymes from plants that function in the defence against fungal and insect pathogens by destroying their chitin-containing cell wall. Class IA/I and IB/II enzymes differ in the presence (IA/I) or absence (IB/II) of a N-terminal chitin-binding doma... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8993_chunk_0 | Glycoside hydrolase family 2 | In molecular biology, Glycoside hydrolase family 2 is a family of glycoside hydrolases EC 3.2.1., which are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8994_chunk_0 | Glycoside hydrolase family 2 | These enzymes contain a conserved glutamic acid residue which has been shown, in Escherichia coli lacZ (P00722), to be the general acid/base catalyst in the active site of the enzyme. The catalytic domain of Beta-galactosidases have a TIM barrel core surrounded several other largely beta domains. The sugar binding doma... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8995_chunk_0 | Human accelerated region 1 | In molecular biology, Human Accelerated Region 1 (Highly Accelerated Region 1, HAR1) is a segment of the human genome found on the long arm of chromosome 20. It is a human accelerated region. It is located within a pair of overlapping long non-coding RNA genes, HAR1A (HAR1F) and HAR1B (HAR1R). | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8996_chunk_0 | Smith antigen | In molecular biology, LSm proteins are a family of RNA-binding proteins found in virtually every cellular organism. LSm is a contraction of 'like Sm', because the first identified members of the LSm protein family were the Sm proteins. LSm proteins are defined by a characteristic three-dimensional structure and their a... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8997_chunk_0 | Smith antigen | Individual LSm proteins assemble into a six or seven member doughnut ring (more properly termed a torus), which usually binds to a small RNA molecule to form a ribonucleoprotein complex. The LSm torus assists the RNA molecule to assume and maintain its proper three-dimensional structure. Depending on which LSm proteins... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8998_chunk_0 | LcrV | In molecular biology, LcrV is a protein found in Yersinia pestis and several other bacterial species. It forms part of the Yersinia pestis virulence protein factors that also includes all Yops, or Yersinia outer protein, but the name has been kept out of convention. LcrV's main function is not actually known, but it is... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_8999_chunk_0 | LcrV | The type III secretion system of Gram-negative bacteria is used to transport virulence factors from the pathogen directly into the host cell and is only triggered when the bacterium comes into close contact with the host. Effector proteins secreted by the type III system do not possess a secretion signal, and are consi... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
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