id stringlengths 14 19 | title stringlengths 1 124 | text stringlengths 12 2.83k | source stringclasses 1
value |
|---|---|---|---|
wiki_9700_chunk_0 | Small nucleolar RNA Z199 | snoRNA Z199 is a member of the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.snoZ199 is predicted to be a methylation guide for sites ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9701_chunk_0 | Small nucleolar RNA Z37 | In molecular biology, snoRNA Z37 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. Z37 acts as a methylation guide for 5.8S ribosomal RNA. This family contains a putative snoRNA found in the intron of the receptor for activated C kinase (RACK1) gene in mammals identified by th... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9702_chunk_0 | Small nucleolar RNA snR57 | In molecular biology, snoRNA snR57 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA)... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9703_chunk_0 | Small nucleolar RNA snR57 | snoRNA snR57 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA snR57 was initially discovered using a computational... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9704_chunk_0 | Small nucleolar RNA snR69 | In molecular biology, snoRNA snR69 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA)... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9705_chunk_0 | Small nucleolar RNA snR69 | snoRNA snR69 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA snR69 was initially discovered using a computational... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9706_chunk_0 | Small nucleolar RNA snR71 | In molecular biology, snoRNA snR71 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA)... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9707_chunk_0 | Small nucleolar RNA snR71 | snoRNA snR71 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. snoRNA snR71 was initially discovered using a computational... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9708_chunk_0 | Subcloning | In molecular biology, subcloning is a technique used to move a particular DNA sequence from a parent vector to a destination vector. Subcloning is not to be confused with molecular cloning, a related technique. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9709_chunk_0 | TRNA-dihydrouridine synthase | In molecular biology, tRNA-dihydrouridine synthase is a family of enzymes which catalyse the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also in some archaea. Most dihydrouridines are found in the D loop of t-RN... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9710_chunk_0 | ADP-ribosylhydrolase | In molecular biology, the (ADP-ribosyl)hydrolase (ARH) family contains enzymes which catalyses the hydrolysis of ADP-ribosyl modifications from proteins, nucleic acids and small molecules. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9711_chunk_0 | 3H domain | In molecular biology, the 3H domain is a protein domain named after its three highly conserved histidine residues. The 3H domain appears to be a smarr molecure-binding domain, based on its occurrence with other domains. Several proteins carrying this domain are transcriptional regulators from the biotin repressor famil... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9712_chunk_0 | 3H domain | TM1602 has an N-terminal DNA-binding domain and a C-terminal 3H regulatory domain. The N-terminal domain appears to bind to the NAD promoter region and repress the de novo NAD biosynthesis operon, while the C-terminal 3H domain may bind to nicotinamide, nicotinic acid, or other substrate/products. The 3H domain has a 2... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9713_chunk_0 | 5.8S rRNA | In molecular biology, the 5.8S ribosomal RNA (5.8S rRNA) is a non-coding RNA component of the large subunit of the eukaryotic ribosome and so plays an important role in protein translation. It is transcribed by RNA polymerase I as part of the 45S precursor that also contains 18S and 28S rRNA. Its function is thought to... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9714_chunk_0 | 5.8S rRNA | 5.8S rRNA can be used as a reference gene for miRNA detection. The 5.8S ribosomal RNA is used to better understand other rRNA processes and pathways in the cell.The 5.8S rRNA is homologous to the 5' end of non-eukaryotic LSU rRNA. In eukaryotes, the insertion of ITS2 breaks LSU rRNA into 5.8S and 28S rRNAs. Some flies ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9715_chunk_0 | ABM domain | In molecular biology, the ABM domain is a protein domain that is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species, which can carry out oxygenation without the assistance of any of the prosthetic groups, metal ions or cofactors normally associated with activation of mol... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9716_chunk_0 | ACT domain | In molecular biology, the ACT domain is a protein domain that is found in a variety of proteins involved in metabolism. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. The ACT domain is named after three of the proteins that contain it: aspartate kinase, chori... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9717_chunk_0 | AMMECR1 | In molecular biology, the AMMECR1 protein (Alport syndrome, intellectual disability, midface hypoplasia and elliptocytosis chromosomal region gene 1 protein) is a protein encoded by the AMMECR1 gene on human chromosome Xq22.3. The contiguous gene deletion syndrome is characterised by Alport syndrome (A), intellectual d... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9718_chunk_0 | AMMECR1 | The C-terminal region of AMMECR1 (from residue 122 to 333) is well conserved, and homologues appear in species ranging from bacteria and archaea to eukaryotes. The high level of conservation of the AMMECR1 domain points to a basic cellular function, potentially in either the transcription, replication, repair or transl... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9719_chunk_0 | AMMECR1 | The size of the cleft suggests that the substrate is large, e.g., the substrate may be a nucleic acid or protein. However, the inner side of the cleft is not filled with positively charged residues, and therefore it is unlikely that negatively charged nucleic acids such as DNA or RNA interact at this site. == Reference... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9720_chunk_0 | AN1 zinc finger | In molecular biology, the AN1-type zinc finger domain, which has a dimetal (zinc)-bound alpha/beta fold. This domain was first identified as a zinc finger at the C terminus of AN1 SWISSPROT, a ubiquitin-like protein in Xenopus laevis. The AN1-type zinc finger contains six conserved cysteines and two histidines that cou... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9721_chunk_0 | ARID domain | In molecular biology, the ARID domain (AT-rich interaction domain; also known as BRIGHT (B-cell Regulator of Ig Heavy chain Transcription) domain)) is a protein domain that binds to DNA. ARID domain-containing proteins are found in fungi, plants and invertebrate and vertebrate metazoans. ARID-encoding genes are involve... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9722_chunk_0 | ARID domain | The basic structure of the ARID domain appears to be a series of six alpha-helices separated by beta-strands, loops, or turns, but the structured region may extend to an additional helix at either or both ends of the basic six. Based on primary sequence homology, they can be partitioned into three structural classes: M... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9723_chunk_0 | ARID domain | The ARID consensus and other structural features are common to both ARID1A and yeast SWI1, suggesting that ARID1A is a human counterpart of SWI1. The approximately 100-residue ARID sequence is present in a series of proteins strongly implicated in the regulation of cell growth, development, and tissue-specific gene exp... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9724_chunk_0 | ARID domain | Each binds preferentially to AT-rich sites. In contrast, ARID1A shows no sequence preference in its DNA binding activity, thereby demonstrating that AT-rich binding is not an intrinsic property of ARID domains and that ARID family proteins may be involved in a wider range of DNA interactions. == References == | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9725_chunk_0 | ASF1 like histone chaperone | In molecular biology, the ASF1 like histone chaperone family of proteins includes the yeast and human ASF1 proteins. These proteins are of the chaperone protein group and in particular can be placed into the histone chaperone subgroup. ASF1 participates in both the replication-dependent and replication-independent path... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9726_chunk_0 | ATCase/OTCase family | In molecular biology, the ATCase/OTCase family is a protein family which contains two related enzymes: aspartate carbamoyltransferase EC 2.1.3.2 and ornithine carbamoyltransferase EC 2.1.3.3. It has been shown that these enzymes are evolutionary related. The predicted secondary structure of both enzymes is similar and ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9727_chunk_0 | ATCase/OTCase family | In prokaryotes ATCase consists of two subunits: a catalytic chain (gene pyrB) and a regulatory chain (gene pyrI), while in eukaryotes it is a domain in a multi- functional enzyme (called URA2 in yeast, rudimentary in Drosophila, and CAD in mammals) that also catalyzes other steps of the biosynthesis of pyrimidines.Orni... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9728_chunk_0 | ATP cone | In molecular biology, the ATP-cone is an evolutionarily mobile, ATP-binding regulatory domain which is found in a variety of proteins including ribonucleotide reductases, phosphoglycerate kinases and transcriptional regulators.In ribonucleotide reductase protein R1 from Escherichia coli this domain is located at the N ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9729_chunk_0 | ATP:guanido phosphotransferase family | In molecular biology, the ATP:guanido phosphotransferase family is a family of structurally and functionally related enzymes, that reversibly catalyse the transfer of phosphate between ATP and various phosphagens. The enzymes belonging to this family include: Glycocyamine kinase (EC 2.7.3.1), which catalyses the transf... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9730_chunk_0 | ATP:guanido phosphotransferase family | Lombricine kinase (EC 2.7.3.5), an annelid-specific enzyme that catalyses the transfer of phosphate from ATP to lombricine. Smc74, a cercaria-specific enzyme from Schistosoma mansoni. Creatine kinase (EC 2.7.3.2) (CK), which catalyses the reversible transfer of high energy phosphate from ATP to creatine, generating pho... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9731_chunk_0 | Acyl-CoA-binding protein | In molecular biology, the Acyl-CoA-binding protein (ACBP) is a small (10 Kd) protein that binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. ACBP is also known as diazepam binding inhibitor (DBI) or endozepine (EP) because of its ability... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9732_chunk_0 | Acyl-CoA-binding protein | The ligand is bound through specific interactions with residues on the protein, most notably several conserved positive charges that interact with the phosphate group on the adenosine-3'phosphate moiety, and the acyl chain is sandwiched between the hydrophobic surfaces of CoA and the protein.Other proteins containing a... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9733_chunk_0 | Acyl-CoA-binding protein | MA-DBI contains a N-terminal ACB domain. DRS-1, a human protein of unknown function that contains a N-terminal ACB domain and a C-terminal enoyl-CoA isomerase/hydratase domain. == References == | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9734_chunk_0 | BAH domain | In molecular biology, the BAH domain (bromo-adjacent homology) domain is found in proteins such as eukaryotic DNA (cytosine-5) methyltransferases, the origin recognition complex 1 (Orc1) proteins, Bromo adjacent homology domain containing 1 (BAHD1), as well as several proteins involved in transcriptional regulation. Th... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9735_chunk_0 | BEN domain | In molecular biology, the BEN domain is a protein domain which is found in diverse proteins including: SMAR1 (Scaffold/Matrix attachment region-binding protein 1; also known as BANP), a tumour-suppressor MAR-binding protein that down-regulates Cyclin D1 expression by recruiting HDAC1-mSin3A co-repressor complex at Cycl... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9736_chunk_0 | BEN domain | Trans-splicing of Mod(mdg4) produces at least 26 transcripts. BEND2, a protein of unknown function, that is predicted to be involved in chromatin modification and has been associated clinically with central nervous system disorders. E5R protein from Chordopoxvirus virosomes, which is found in cytoplasmic sites of viral... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9737_chunk_0 | BEN domain | Several proteins of polydnaviruses.The BEN domain is predicted to function as an adaptor for the higher-order structuring of chromatin, and recruitment of chromatin modifying factors in transcriptional regulation. It has been suggested to mediate protein-DNA and protein-protein interactions during chromatin organizatio... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9738_chunk_0 | BESS domain | In molecular biology, the BESS domain is a protein domain which has been named after the three proteins that originally defined the domain: BEAF (Boundary element associated factor 32), Suvar(3)7 and Stonewall ). The BESS domain is 40 amino acid residues long and is predicted to be composed of three alpha helices, as s... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9739_chunk_0 | BESS domain | Drosophila Suppressor of variegation protein 3-7 (Su(var)3-7), which could play a role in chromosome condensation. Drosophila Ravus, which is homologous to the C-terminal part of Su(var)3-7. Drosophila Stonewall (Stwl), a putative transcription factor required for maintenance of female germline stem cells as well as oo... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9740_chunk_0 | BESS domain | Drosophila Adf-1, a transcription factor first identified on the basis of its interaction with the alcohol dehydrogenase promoter but that binds the promoters of a diverse group of genes. Drosophila Dorsal-interacting protein 3 (Dip3). It functions both as an activator to bind DNA in a sequence specific manner and a co... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9741_chunk_0 | BLUF domain | In molecular biology, the BLUF domain (sensors of blue-light using FAD) is a FAD-binding protein domain. They are present in various proteins, primarily from bacteria, for example a BLUF domain is found at the N-terminus of the AppA protein from Rhodobacter sphaeroides. The BLUF domain is involved in sensing blue-light... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9742_chunk_0 | BPS domain | In molecular biology, the BPS domain (Between PH and SH2) domain is a protein domain of approximately 45 amino acids found in the adaptor proteins Grb7/|Grb10/Grb14. It mediates inhibition of the tyrosine kinase domain of the insulin receptor by binding of the N-terminal portion of the BPS domain to the substrate pepti... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9743_chunk_0 | BSD domain | In molecular biology, the BSD domain is an approximately 60-amino-acid-long protein domain named after the BTF2-like transcription factors, synapse-associated proteins and DOS2-like proteins in which it is found. It is also found in several hypothetical proteins. It occurs in one or two copies in a variety of species r... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9744_chunk_0 | BSD domain | The third predicted helix contains neighbouring phenylalanine and tryptophan residues—less common amino acids that are invariant in all the BSD domains identified and that are the domain's most striking sequence features.Some proteins known to contain one or two BSD domains are: Mammalian TFIIH basal transcription fact... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9745_chunk_0 | BURP domain | In molecular biology, the BURP domain is a ~230-amino acid protein domain, which has been named for the four members of the group initially identified, BNM2, USP, RD22, and PG1beta. It is found in the C-terminal part of a number of plant cell wall proteins, which are defined not only by the BURP domain, but also by the... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9746_chunk_0 | BURP domain | The presence of the conserved BURP domain in diverse plant proteins suggests an important role for this domain. It is possible that the BURP domain represents a general motif for localization of proteins within the cell wall matrix. The other structural domains associated with the BURP domain may specify other target s... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9747_chunk_0 | BURP domain | Field bean USPs, abundant non-storage seed proteins with unknown function. Soybean USP-like proteins ADR6 (or SALI5-4A), an auxin-repressible, aluminium-inducible protein and SALI3-2, a protein that is up-regulated by aluminium. Soybean seed coat BURP-domain protein 1 (SCB1). | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9748_chunk_0 | BURP domain | It might play a role in the differentiation of the seed coat parenchyma cells. Arabidopsis RD22 drought induced protein. Maize ZRP2, a protein of unknown function in cortex parenchyma. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9749_chunk_0 | Bacillus haemolytic enterotoxin | In molecular biology, the Bacillus haemolytic enterotoxin family of proteins consists of several Bacillus haemolytic enterotoxins (HblC, HblD, HblA, NheA, and NheB), which can cause food poisoning in humans. Haemolysin BL (encoded by HBL) and non-haemolytic enterotoxin (encoded by NHE), represent the major enterotoxins... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9750_chunk_0 | Bacillus haemolytic enterotoxin | It is possible that the common structural and functional properties of these toxins indicate that the Hbl/Nhe and ClyA families of toxins constitute a superfamily of pore-forming cytotoxins. Haemolysin BL and non-haemolytic enterotoxin production are both influenced by pH and micro. == References == | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9751_chunk_0 | Bcl-x interacting domain | In molecular biology, the Bcl-x interacting domain is a protein domain found in BAM, Bim and Bcl2-like protein 11. It is a long alpha helix, which is required for interaction with Bcl-x. == References == | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9752_chunk_0 | BmKK2 toxin | In molecular biology, the BmKK2 toxins are a family of scorpion toxins. They belong to the scorpion toxin subfamily alpha-KTx 14. They include a novel short-chain peptide from the Asian scorpion Mesobuthus martensii Karsch, a potassium channel blocker composed of 31 amino acid residues. The peptide adopts a classical a... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9753_chunk_0 | BmKK2 toxin | BmKK2 selectively inhibits the delayed rectifier K+ current, but does not affect the fast transient K+ current.In comparison with typical short-chain scorpion toxins (e.g., CTX and NTX), the alpha helix is shorter and the beta-sheet element is smaller (each strand consists of only two residues). There is an alpha-mode ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9754_chunk_0 | BolA-like protein family | In molecular biology, the BolA-like protein family consists of the morpho-protein BolA from Escherichia coli, the Fra2 protein from Saccharomyces cerevisiae, and various homologs. The BolA protein is a DNA-binding regulator; the Fra2 protein is an iron sulfur cluster protein that binds Grx3/4 and is involved in regulat... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9755_chunk_0 | BolA-like protein family | BolA is also induced by stress during early stages of growth and may have a general role in stress response. It has also been suggested that BolA can induce the transcription of penicillin binding proteins 6 and 5. == References == | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9756_chunk_0 | Bowman–Birk protease inhibitor | In molecular biology, the Bowman–Birk protease inhibitor family of proteins consists of eukaryotic proteinase inhibitors, belonging to MEROPS inhibitor family I12, clan IF. They mainly inhibit serine peptidases of the S1 family, but also inhibit S3 peptidases.Members of this family have a duplicated structure and gener... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9757_chunk_0 | BsuBI/PstI restriction endonuclease | In molecular biology, the BsuBI/PstI restriction endonuclease family is a family of type II restriction endonucleases. It includes BsuBI and PstI. The enzymes of the BsuBI restriction/modification (R/M) system recognise the target sequence 5'CTGCAG and are functionally identical with those of the PstI R/M system. == Re... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9758_chunk_0 | Btk-type zinc finger | In molecular biology, the Btk-type zinc finger or Btk motif (BM) is a conserved zinc-binding motif containing conserved cysteines and a histidine that is present in certain eukaryotic signalling proteins. The motif is named after Bruton's tyrosine kinase (Btk), an enzyme which is essential for B cell maturation in huma... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9759_chunk_0 | Btk-type zinc finger | A complete TH domain, containing both the Btk and PRR regions, has not been found outside the Tec family; however, the Btk motif on its own does occur in other proteins, usually C-terminal to a PH domain (note that although a Btk motif always occurs C-terminal to a PH domain, not all PH domains are followed by a Btk mo... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9760_chunk_0 | BtpA protein | In molecular biology, the BtpA protein family is a family of proteins which includes BtpA. BtpA appears to play a role in the stabilisation of photosystem I . It is an extrinsic membrane protein located on the cytoplasmic side of the thylakoid membrane. Homologs of BtpA are found in the Thermoproteota and "Euryarchaeot... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9761_chunk_0 | Btz domain | In molecular biology, the Btz domain (CASC3/Barentsz eIF4AIII binding domain) is a protein domain found on CASC3 (cancer susceptibility candidate gene 3 protein) which is also known as Barentsz (Btz). CASC3 is a component of the EJC (exon junction complex) which is a complex that is involved in post-transcriptional reg... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9762_chunk_0 | CAS/CSE protein family | In molecular biology, the CAS/CSE protein family is a family of proteins which includes mammalian cellular apoptosis susceptibility (CAS) proteins and yeast chromosome-segregation protein, CSE1. CAS is involved in both cellular apoptosis and proliferation. Apoptosis is inhibited in CAS-depleted cells, while the express... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9763_chunk_0 | CAS/CSE protein family | In the nucleus, CAS acts as a nuclear transport factor in the importin pathway. The importin pathway mediates the nuclear transport of several proteins that are necessary for mitosis and further progression. CAS is therefore thought to affect the cell cycle through its effect on the nuclear transport of these proteins. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9764_chunk_0 | CAT RNA-binding domain | In molecular biology, the CAT RNA-binding domain (Co-AntiTerminator RNA-binding domain) is a protein domain found at the amino terminus of a family of transcriptional antiterminator proteins. This domain forms a dimer in the crystal structure. Transcriptional antiterminators of the BglG/SacY family are regulatory prote... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9765_chunk_0 | CBS domain | In molecular biology, the CBS domain is a protein domain found in a range of proteins in all species from bacteria to humans. It was first identified as a conserved sequence region in 1997 and named after cystathionine beta synthase, one of the proteins it is found in. CBS domains are also found in a wide variety of ot... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9766_chunk_0 | CD20-like family | In molecular biology, the CD20-like family of proteins includes the CD20 protein and the beta subunit of the high affinity receptor for IgE Fc, MS4A2. MS4A2 has a tetrameric structure consisting of a single IgE-binding alpha subunit, a single beta subunit, and two disulfide-linked gamma subunits. It has four putative t... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9767_chunk_0 | CD20-like family | This family also includes LR8 like proteins from humans (TMEM176B), mice and rats. The function of the human LR8 protein is unknown although it is known to be strongly expressed in the lung fibroblasts. This family also includes sarcospan, a transmembrane component of dystrophin-associated glycoprotein. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9768_chunk_0 | CDC48 N-terminal domain | In molecular biology, the CDC48 N-terminal domain is a protein domain found in AAA ATPases including cell division protein 48 (CDC48), VCP-like ATPase and N-ethylmaleimide sensitive fusion protein. It is a substrate recognition domain which binds polypeptides, prevents protein aggregation, and catalyses refolding of pe... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9769_chunk_0 | CFC domain | In molecular biology, the CFC domain (Cripto_Frl-1_Cryptic domain) is a protein domain found at the C-terminus of a number of proteins including Cripto (or teratocarcinoma-derived growth factor). It is structurally similar to the C-terminal extracellular portions of Jagged 1 and Jagged 2. CFC is approx 40-residues long... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9770_chunk_0 | CHAP domain | In molecular biology, the CHAP domain is a region between 110 and 140 amino acids that is found in proteins from bacteria, bacteriophages, archaea and eukaryotes of the family Trypanosomidae. The domain is named after the acronym cysteine, histidine-dependent amidohydrolases/peptidases. Many of these proteins are uncha... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9771_chunk_0 | CHB HEX N-terminal domain | In molecular biology, the CHB HEX N-terminal domain represents the N-terminal domain in chitobiases and beta-hexosaminidases. Chitobiases degrade chitin, which forms the exoskeleton in insects and crustaceans, and which is one of the most abundant polysaccharides on earth. Beta-hexosaminidases are composed of either a ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9772_chunk_0 | CHB HEX N-terminal domain | HexB is structurally similar to chitobiase, consisting of a beta sandwich structure; this structure is similar to that found in the cellulose-binding domain of cellulase from Cellulomonas fimi. This domain may function as a carbohydrate binding module. == References == | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9773_chunk_0 | CLP protease family | In molecular biology, the CLP protease family is a family of serine peptidases belong to the MEROPS peptidase family S14 (ClpP endopeptidase family, clan SK). ClpP is an ATP-dependent protease that cleaves a number of proteins, such as casein and albumin. It exists as a heterodimer of ATP-binding regulatory A and catal... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9774_chunk_0 | CRM domain | In molecular biology, the CRM domain is an approximately 100-amino acid RNA-binding domain. The name CRM (chloroplast RNA splicing and ribosome maturation) has been suggested to reflect the functions established for four characterised members of the family: Zea mays (Maize) CRS1, CAF1 and CAF2 proteins and the Escheric... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9775_chunk_0 | CRM domain | It has been suggested that prokaryotic CRM proteins existed as ribosome-associated proteins prior to the divergence of archaea and bacteria, and that they were co-opted in the plant lineage as RNA binding modules by incorporation into diverse protein contexts. Plant CRM domains are predicted to reside not only in the c... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9776_chunk_0 | CRM domain | The beta sheet face is basic, consistent with a role in RNA binding. Proximal to the basic beta sheet face is another moiety that could contribute to nucleic acid recognition. Connecting strand beta1 and helix alpha2 is a loop with a six amino acid motif, GxxG flanked by large aliphatic residues, within which one 'x' i... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9777_chunk_0 | CRM domain | GFP fused to a single-domain CRM protein from maize localises to the nucleolus, suggesting that an analogous activity may have been retained in plants. A CRM domain containing protein in plant chloroplasts has been shown to function in group I and II intron splicing. In vitro experiments with an isolated maize CRM doma... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9778_chunk_0 | CRM domain | These and other results suggest that the CRM domain evolved in the context of ribosome function prior to the divergence of Archaea and Bacteria, that this function has been maintained in extant prokaryotes, and that the domain was recruited to serve as an RNA binding module during the evolution of plant genomes. YhbY h... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9779_chunk_0 | Crp domain | In molecular biology, the CRP domain is a protein domain consisting of a helix-turn-helix (HTH) motif. It is found at the C-terminus of numerous bacterial transcription regulatory proteins. These proteins bind DNA via the CRP domain. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9780_chunk_0 | CUT domain | In molecular biology, the CUT domain (also known as ONECUT) is a DNA-binding motif which can bind independently or in cooperation with the homeodomain, which is often found downstream of the CUT domain. Proteins display two modes of DNA binding, which hinge on the homeodomain and on the linker that separates it from th... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9781_chunk_0 | CVNH domain | In molecular biology, the CVNH domain (CyanoVirin-N Homology domain) is a conserved protein domain. It is found in the sugar-binding antiviral protein cyanovirin-N (CVN) as well as proteins from filamentous ascomycetes and in the fern Ceratopteris richardii.Cyanovirin-N (CV-N) is an 11-kDa protein from the cyanobacteri... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9782_chunk_0 | Cbl TKB domain | In molecular biology, the Cbl TKB domain (tyrosine kinase binding domain), also known as the phosphotyrosine binding (PTB) domain is a conserved region found at the N-terminus of Cbl adaptor proteins. This N-terminal region is composed of three evolutionarily conserved domains: an N-terminal four-helix bundle domain, a... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9783_chunk_0 | Cfr10I/Bse634I | In molecular biology, the Cfr10I/Bse634I family of restriction endonucleases includes the type II restriction endonucleases Cfr10I and Bse634I. They exhibit a conserved tetrameric architecture that is of functional importance, wherein two dimers are arranged, back-to-back, with their putative DNA-binding clefts facing ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9784_chunk_0 | CodY protein family | In molecular biology, the CodY protein family consists of several bacterial GTP-sensing transcriptional pleiotropic repressor CodY proteins. CodY has been found to repress the dipeptide transport operon (dpp) of Bacillus subtilis in nutrient-rich conditions. The CodY protein also has a repressor effect on many genes in... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9785_chunk_0 | Cofactor transferase family | In molecular biology, the Cofactor transferase family is a family of protein domains that includes biotin protein ligases, lipoate-protein ligases A, octanoyl-(acyl carrier protein):protein N-octanoyltransferases, and lipoyl-protein:protein N-lipoyltransferases. The metabolism of the cofactors Biotin and lipoic acid sh... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9786_chunk_0 | Cofactor transferase family | Each organism likely has only one BPL protein. Biotin attachment is a two step reaction that results in the formation of an amide linkage between the carboxyl group of biotin and the epsilon-amino group of the modified lysine. Biotin attachment is required for biotin biosynthesis and utilization of free biotin.Lipoate-... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9787_chunk_0 | Cofactor transferase family | They are required for the utilization of free lipoic acid.Octanoyl-(acyl carrier protein):protein N-octanoyltransferases, or octanoyltransferases, are required for lipoic acid biosynthesis. They transfer octanoate from the acyl carrier protein (ACP), part of fatty acid biosynthesis, to the specific lysine residue of li... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9788_chunk_0 | Cofactor transferase family | They transfer lipoic acid or octanoate from lipoyl domains and transfer to other lipoyl domains. In Bacillus subtilis, the transfer is from the glycine cleavage system H protein, GcvH, to other lipoyl domains. This is because the octanoyltransferase of B. subtilis is specific for GcvH. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9789_chunk_0 | Cro repressor family | In molecular biology, the Cro repressor family is a family of repressor proteins in bacteriophage lambda that includes the Cro repressor. Bacteriophage lambda encodes two repressors: the Cro repressor that acts to turn off early gene transcription during the lytic cycle, and the lambda or cI repressor required to maint... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9790_chunk_0 | Cro repressor family | The crystal structure of the lambda Cro repressor reveals a HTH DNA-binding protein with an alpha/beta fold that differs from other Cro family members, possibly by an evolutionary fold change. Most Cro proteins, such as Enterobacteria phage P22 Cro and Bacteriophage 434 Cro, have an all-alpha structure that is thought ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9791_chunk_0 | Cys/Met metabolism PLP-dependent enzyme family | In molecular biology, the Cys/Met metabolism PLP-dependent enzyme family is a family of proteins including enzymes involved in cysteine and methionine metabolism which use PLP (pyridoxal-5'-phosphate) as a cofactor. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9792_chunk_0 | DEP domain | In molecular biology, the DEP domain (Dishevelled, Egl-10 and Pleckstrin domain) is a globular protein domain of about 80 amino acids that is found in over 50 proteins involved in G-protein signalling pathways. It was named after the three proteins it was initially found in: Dishevelled (Dsh and Dvl), which plays a key... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9793_chunk_0 | DHH phosphatase family | In molecular biology, the DHH phosphatase family is a family of putative phosphoesterases. The family includes Drosophila prune protein and bacterial RecJ exonuclease. The RecJ protein of Escherichia coli plays an important role in a number of DNA repair and recombination pathways. | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9794_chunk_0 | DHH phosphatase family | RecJ catalyses processive degradation of single-stranded DNA in a 5'-to-3' direction. Sequences highly related to those encoding RecJ can be found in many of the eubacterial genomes sequenced to date. == References == | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9795_chunk_0 | DSS1/SEM1 protein family | In molecular biology, the DSS1/SEM1 protein family is a family of short acidic proteins which includes the 26S proteasome complex subunits SEM1 from Saccharomyces cerevisiae and Drosophila and DSS1 (SHFM1) in mammals. In Saccharomyces cerevisiae, SEM1 is a regulator of both exocyst function and pseudohyphal differentia... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9796_chunk_0 | DinI-like protein family | In molecular biology, the DinI-like protein family is a family of short proteins. The family includes DNA-damage-inducible protein I (DinI) and related proteins. The SOS response, a set of cellular phenomena exhibited by eubacteria, is initiated by various causes that include DNA damage-induced replication arrest, and ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9797_chunk_0 | DmpG-like communication domain | In molecular biology, the DmpG-like communication domain is a protein domain found towards the C-terminal region of various aldolase enzymes. It consists of five alpha-helices, four of which form an antiparallel helical bundle that plugs the C terminus of the N-terminal TIM barrel domain. The communication domain is th... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9798_chunk_0 | DpnII restriction endonuclease family | In molecular biology, the DpnII restriction endonuclease family is a family of restriction endonucleases which includes DpnII from Diplococcus pneumoniae. These enzymes recognise the double-stranded DNA unmethylated sequence GATC and cleave before G-1, where it encompasses the full length of the protein. == References ... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
wiki_9799_chunk_0 | DyP-type peroxidase family | In molecular biology, the DyP-type peroxidase family is a family of haem peroxidase enzymes. Haem peroxidases were originally divided into two superfamilies, namely, the animal peroxidases and the plant peroxidases (which are subdivided into class I, II and III), which include fungal (class II) and bacterial peroxidase... | https://www.kaggle.com/datasets/conjuring92/wiki-stem-corpus |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.