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135
47978c7d-8176-4c2c-bda2-ae6bbf235841
"Onion-skin" fibrosis of bile duct is seen in
Primary biliary cirrhosis
Primary sclerosing cholangitis
Extrahepatic biliary fibrosis
Congenital hepatic fibrosis
1b
single
Pathology of Primary sclerosing cholangitis Cholangiocytea, epithelial cells that lines the bile duct are target cell of injury in PSC Histologic finding "Onion skin appearance" is pathognomic of PSC, but seen in <10% cases Involvement of large intrahepatic and extrahepatic duct distinguishes PSC from PBC Absence of th...
Anatomy
G.I.T
13a7ceee-27d9-46d6-bc59-25bd6089b19f
Cullen's sign -
Bluish disclolouration of the flanks
Bluish disclolouration of the flanks
Migratory thrombophelebitis
Subcutaneous fat necrosis
1b
single
Ans. is 'b' i.e., Bluish discolouration in the umbilicus Cullen's sign - Bluish discoloration at the umbilicus Grey Turner's sign - Bluish discoloration at the flanks Ct. Mnemonic: GF (Girl Friend) Cullens --> Umbilicus Grey Turner's --> Flanks
Surgery
null
87990c46-df6a-4998-bed1-28a13cf45dee
A 25-year-old woman sustains a deep, open laceration over her right forearm in a motorcycle accident. The wound is cleaned and sutured. Which of the following cell types mediates contraction of the wound to facilitate healing?
Endothelial cells
Fibroblasts
Macrophages
Myofibroblasts
3d
single
The myofibroblast is the cell responsible for wound contraction as well as the deforming pathologic process termed wound contracture. Myofibroblasts exe their contractile effects by forming syncytia,in this they are bound together by tight junctions. -Fibroblasts (choice B) tend to be solitary cells, surrounded by coll...
Pathology
Wound Healing
52218ca8-bf46-407e-973b-94989c5e7fc9
A 27 year old sexually active male develops a vesicobullous lesion on the glans soon after taking tab paracetamol for fever. The lesion healed with hyper pigmentation. The most likely diagnosis is:
Bechet's syndrome
Herpes genitalis
Fixed drug eruption
Pemphigus vulgaris
2c
multi
C ie Fixed drug eruption Fixed Drug Eruption - Adverse cutaneous drug reaction appearing soon after ingestions (from 30 min to 8-16 hours) of offending agent in previously sensitized individuals - Numerous drugs, including anti-inflammatory agents (eg salicylates, NSAID's including paracetamol), phenylhutazone, phenace...
Skin
null
56c5fb3a-4287-409d-8260-cf2afdacec68
A patient suffering from AIDS presents with history of dyspnea and non- productive cough x-ray shows bilateral perihilar opacities without pleural effusion and lymphaden-opathy. Most probable etiological agent is :
Tuberculosis
CMV
Kaposis sarcoma
Pneumocystis carinii
3d
single
D i.e. Pneumocystic carinii
Radiology
null
8de3b25e-7b5a-4e3d-807e-90aca6890ab0
Which of the following is true about P. Falciparum -
James donts are seen
Accole forms are seen
Relapses are frequent
Longest incubation period
1b
multi
P.falciparum Forms in peripheral blood-ring forms and gametocytes (crescent shaped) A) Most pathogenic B). No relapses in P.falciparum-exo-erythrocytic schizogony is absent C). Complications-pernicious malaria,black water fever D)pernicious malaria-1). Cerebral malaria-hyperpyrexia, coma,paralysis.Brain is congested.Ca...
Microbiology
parasitology
ff2f1fde-9356-4e89-9ed5-cc073b0a5557
The outer covering of diatom is made of ?
Magnesium
Silica
Hydrocarbons
None
1b
multi
Ans. is 'b' i.e., Silicon The extracellular coat of diatoms has silica. Diatoms are unicellular algae, suspended in water. They have silicaceous cell wall (i.e. cell wall contains silica) which resist acid digestion and putrefaction. Only live body with a circulation can transpo diatoms form lung to brain, bone marrow,...
Forensic Medicine
null
ffd1f9fc-0803-4016-af86-5721e1d0a726
Which of the following is not a side effect of clozapine:
Agranulocytosis
Seizures
Sialosis
Weight loss
3d
single
Ref: KDT 6/e p429 Clozapine and other atypical antipsychotic resulting weight gain.
Pharmacology
Central Nervous system
5ccbd9dc-f8d4-40c7-a42b-102c99ee2d73
Most cardiotoxic local anesthetic ?
Procaine
Bupivacaine
Cocaine
Lidocaine
1b
single
Ans. is 'b' i.e., Bupivacaine
Anaesthesia
null
e4d6faec-a13d-4a4c-96bf-88267b021fcc
True about DNA reconstruction technology
Restriction endonucleases are involved
DNA ligase is used
Acid phosphatase is used
Reverse transcriptase needed
0a
multi
DNA phenotyping (fee-no-type-ing) is the process of predicting an organism's phenotype using only genetic information collected from genotyping or DNA sequencing. This term, also known as molecular photofitting, is primarily used to refer to the prediction of a person's physical appearance and/or biogeographic ancestry...
Biochemistry
Metabolism of nucleic acids
8229551e-04a4-41e0-b45e-4499fb7c8c30
Purple coloured reamer is numbered:
8
10
15
30
1b
single
null
Dental
null
e646f3f3-65dc-4868-adb8-292793371de4
Which of the following antibodies is highly specific for systemic lupus erythematosus -
Anti-Sm
Anti-RO-1
Anti-UIRNP
Anti-Centeromere
0a
single
Ans. is 'a' i.e., Anti-Sm
Medicine
SLE
0115ebc8-295f-4460-a060-7293f15ebe0e
Which of the following artery supplies parathyroid glands?
Superior thyroid artery
Inferior thyroid artery
Common carotid artery
Middle thyroid artery
1b
single
Ans. B Inferior thyroid arteryRef: Gray's, 41sted. pg. 472* Both upper & lower parathyroid glands are supplied by the inferior thyroid arteryVascular Supply and Lymphatic Drainage of Parathyroid Gland* Inferior thyroid arteries provide primary blood supply to posterior aspect of thyroid gland and parathyroid glands (wh...
Anatomy
Neuroanatomy
f8dafdc2-6aca-44ed-8351-44a86a610492
The voice in a patient with bilateral abductor paralysis of larynx is:
Puberuophonia
Phonasthenia
Dysphonia plicae ventricularis
Normal or good voice
3d
single
Ans. is d i.e. normal or good voice Management Lateralization of cord by arytenoidectomy, endoscopic surgery, thyroplasty type II, cordectomy In emergency cases -Tracheostomy may be required Also know Generally patients with bilateral recurrent laryngeal nerve palsy have a recent history of thyroid surgery or rarely an...
ENT
null
a2019989-5010-458f-821b-b10152ac2ee5
Time interval between acute and persistent psychotic disease is ?
1 week
2 week
3 week
1 months
3d
single
Ans. is `d' i.e., 1 months If symtoms are for less than 1 months, it is transient psychotic disorder and if there are for more than 1 months, it is persistent psychotic disorder (persistent delusional disorder). Note:- Diagnosic criteria for delusional disorder (Persistent delusion disorder) has different durations in ...
Psychiatry
null
a2a728a5-4b89-4d8e-9e3e-660fad73e75a
Which interleukin is needed for differentiation of eosinophils: September 2009
IL1
IL2
IL4
IL5
3d
single
Ans. D: IL5
Physiology
null
8e34ab02-8c87-464e-b558-5da288829166
An injury to the shown area can lead to fracture of which bone (FMGE June 2019)
Lunate
Scaphoid
Hamate
Trapezium
1b
single
Anatomical snuff box: The given picture shows anatomical snuff box which is a depression formed at the posterolateral side of the wrist and metacarpal by the extensor tendons passing into the thumb. Base of the triangle is at the wrist and apex is directed into thumb. It is most apparent when thumb is extended. Boundar...
Anatomy
FMGE 2019
7dc712c5-5269-408a-8ed7-edbb3f8467d5
Injury to long thoracic nerve leads to
Winging of scapula
Pointing index
Claw hand
Wrist drop
0a
single
Injury to long thoracic nerve causes paralysis of serratus anterior muscle which clinically manifests as winging of scapula. The patient also finds difficulty in overhead abduction and touching the opposite shoulder. B D Chaurasia 7th edition Page no: 45
Anatomy
Upper limb
2c7a1b1a-35ca-4e02-aae1-df107d9b5ec5
Drug of choice in dermatitis herpetiformis is:
Corticosteroids
Colchicine
Dapsone
Chloroquine
2c
single
Ans. (c) DapsoneRef. katzung 11th ed. /1468* Dermatitis herpetiformis is a chronic blistering skin condition, characterised by blisters filled with a watery fluid.* DH is neither related to nor caused by herpes virus: the name means that it is a skin inflammation having an appearance similar to herpes.* It characterize...
Pharmacology
Anti-Leprotic
2739538d-1d47-4327-99b3-3070e378d912
Which of the following is the preferred local anesthetic technique for hemophiliacs?
Nerve block
Supraperiosteal
Intraligamentary
Field block
2c
single
null
Surgery
null
6c160be8-fcf3-4fd5-9de8-150039853a5f
A 35-year-old man is taken to the emergency depament because he is coughing up large volumes of blood. He does not have any history suggestive of exposure to tuberculosis, and a chest x-ray film does not show a mass lesion. Chest x-ray films performed on the day of admission and daily for the next several days show asy...
Bullous pemphigoid
Graves disease
Hereditary angioedema
Rheumatoid ahritis
0a
multi
This patient has Goodpasture syndrome, which is a rare, severe autoimmune disease in which antibodies directed against the basement membrane in pulmonary alveoli and renal glomeruli predispose for hemoptysis and progressive renal disease. These patients can die because of exsanguination, asphyxiation by blood, or renal...
Medicine
null
cb36929f-032a-4b15-93a2-b1f542dcc0c1
A povey-stricken mother suffering from active tuberculosis delivers a baby. Which one of the following advices would be the most appropriate in her case -
Breast feeding and BCG immunization
Breast feeding and isoniazid administration
Expressed breast milk and BCG immunization
Stop feeds and isoniazid administration
1b
single
Ans. is 'b' i.e., Breast feeding and isoniazid administration o The best answer would have been --> Breast feeding + INH + BCG vaccination.
Pediatrics
null
3be6ba1d-a69e-4041-84bd-8765d2fa249a
The sago spleen and lardaceous spleen are conditions seen in-
Congestive splenomegaly
Autosplenectomy
Secondaries in spleen
Amyloidosis of the spleen
3d
single
Amyloidosis of SpleenAmyloid deposition in the spleen, for some unknown reasons, may have one of the following two patterns:1. SAGO SPLEEN. The splenomegaly is not marked and cut surface shows characteristic translucent pale and waxy nodules resembling sago grains and hence the name.Microscopically, the amyloid deposit...
Pathology
miscellaneous
9fed0184-5324-482f-9b5e-e008998c1503
All of the following characteristic pattern seen in Brown-Sequard syndrome; except:
Ipsilateral weakness
Ipsilateral loss of position and vibration
Ipsilateral loss of pain and temperature
Contralateral loss of pain and temperature
2c
multi
Ans. c. Ipsilateral loss of pain and temperatureRef: Ganongs Review of Medical Physiology 25th Ed; Page No-172BROWN-SEQUARD SYNDROMEBrown-Sequard syndrome is caused by damage to one half of the spinal cord, resulting in paralysis and loss of proprioception on the same (or ipsilateral) side as the injury or lesion, and ...
Physiology
Nervous System
697c8087-a7e8-487f-b3b3-07eb7c4d0f51
Mandibular 1st molar has:
2 roots and 2 canals
2 roots and 3 canals
3 roots and 3 canals
3 roots and 4 canals
1b
single
null
Dental
null
783d71a9-fccf-4259-98cb-0e5ed306114f
In simple hanging, the knot comes to rest at the: September 2009
Occiput
Chin
Angle of mandible
Below the cheek
2c
single
Ans. C: Angle of mandible In most hanging deaths, the ligature and ligature mark lie above the thyroid prominence, with a point of suspension usually behind one ear. Frontal knots are unusual. The appearance of the ligature mark varies with the type of ligature used and with the physical characteristics of the individu...
Forensic Medicine
null
aab2fe18-065e-46d1-8157-caea468b2d71
Injury of common peroneal nerve at the lateral aspect of head of fibula results in all of the following except -
Weakness of ankle dorsi-flexion
Foot drop
Loss of ankle reflex
Sensory impairment on lateral aspect of leg extending to the dorsum of foot
2c
multi
Common peroneal nerve injury may result in -  Foot drop -  Weakness of dorsiflexion -  Inability to extend the toes. -  Loss of eversion -  Sensory loss Anterior side of leg Lateral side of leg Dorsum of foot and toes (including medial side of big toe) Common peroneal nerve injury does not affect -  Sensation on late...
Anatomy
null
326e84ff-b473-43ec-9f8d-3287a680c416
Which of following antibody is pentameric -
IgM
IgG
IgA
IgD
0a
single
Ans. is 'a' i.e., IgM * Ig M is a pentameric immunoglobulin with five, four - peptide subunits.* The subunits are joined together by J chain.Remember* J chain is found in IgA and IgM.Also know* I think the following information requires some specific mention here-# There may be confusion about the status of momomer and...
Microbiology
Immunology
d33d9183-5145-44a5-8bb8-908ea1944448
Pelkan's spur is seen in?
Rickets
Hypopituitarism
Scurvy
Hypothyroidism
2c
single
Severe vitamin C deficiency causes scurvy. The usual age of onset is 6 to 18 months. Pseudoparalysis is commonly seen. Hemorrhages occur under the periosteum of long bones. Gum bleeds are common. Costochondral junctions become prominent and appears sharp and angular. Scorbutic rosary is attributed to the separation of ...
Pediatrics
null
084aa1d7-88f7-4945-b1f9-0f97f065f484
Which of the following is NOT a content of the axilla:
Axillary vessels
Axillary tail of the breast
Roots of brachial plexus
Intercostobrachial nerve
2c
single
Contents of axillaAxillary aery and its branchesAxillary vein and its tributariesInfraclavicular pa of brachial plexusFive groups of axillary lymph nodes and the associated lymphaticsThe long thoracic and intercostobrachial nerveAxillary fat and areolar tissue in which the other contents are embeddedLymph nodes of axil...
Anatomy
null
76d21c33-d9d2-4d54-9cd7-05f02415217a
What is a Baker's Cyst -
Gluteal Abscess
Cyst on the posterior aspect of the thigh
Cyst over the popliteal fossa
Swelling of the bursa of semiteninosus and gracilis
2c
single
Ans. is 'c' i.e., Cyst over the popliteal fossa Baker's Cvsto A Baker's cyst, also known as a popliteal cyst, is a benign swelling of the semimembranosus or more rarely some othersynovial bursa found behind the knee joint.o Diagnosis is by examination. A Baker's cyst is easier to see from behind with the patient standi...
Surgery
Orthopedics
4316633d-d026-4881-a698-fa68a4dbafae
Inability to suck on a straw may indicate lesion of which nerve?
II
V
VII
IX
2c
single
The orbicularis oris muscle encircles the opening of the mouth and helps to bring the lips together to keep the mouth closed. Pursing of mouth is due to orbicularis oris inseed into lips and angle of mouth supplied by VII nerve.The muscles of facial expression are innervated by branches of the facial nerve (VII). After...
Anatomy
null
bedb4726-66bf-4dae-9d3b-3f4a94478520
Emile Durkheim is linked with work on which condition is psychiatry
Suicide
Obsessive compulsive disorder
Anxiety disorder
Schizophrenia
0a
single
Durkheim's theory: first major contribution to the study of social and cultural influences on suicide was made by french sociologist Emile Durkheim. He divided suicides into three social categories- Egoistic, Altruistic amd Anomic. Ref: Synopsis of Psychiatry, 11e, pg 766.
Psychiatry
Cognitive development and defence mechanism
80645cce-f833-482e-8ec7-41f98bd443a2
Glycosylated haemoglobin reflects the mean blood glucose level of previous
15 days
1 month
3 months
6 months
2c
single
null
Social & Preventive Medicine
null
cb9b861d-4529-4aa5-9ada-64c0b2ff3887
Which one of the following statements truly represents Bell's paralysis?
Facial nerve paralysis and contralateral Hemiparesis
Combined paralysis of the facial, trigeminal and abducens nerves
Idiopathic ipsilateral paralysis of the facial nerve
Facial nerve paralysis with uveitis and parotid enlargement
2c
multi
(c) Bell's palsy is idiopathic LMN palsy of facial nerve causing ipsilateral paralysis of face.(Ref. Scott Brown, 6th ed., 1400)Ipsilateral Facial nerve paralysis and contralateral Hemiparesis along with ipsilateral VI nerve palsy constitutes Millard Gubler syndrome. It is a form of "crossed hemiplegia," as the paralys...
ENT
Facial Nerve And Its Disorders
c4e4de70-9ced-4d80-80a8-4dd08b58b375
In a specimen of kidney, fibrinoid necrosis is seen and onion peel appearance is also present. Most probable pathology is:
Hyaline degeneration
Hyperplastic aeriosclerosis
Glomerulosclerosis
Fibrillary glomerulonephritis
1b
single
Histological alterations characterizing blood vessels in malignant hypeension. ? Hyperplastic aeriosclerosis Fibrinoid necrosis of aerioles: Onion-skinning (concentrically arranged smooth muscle with collagen).
Pathology
Basic Concepts
1665705e-1152-4511-9e8e-251d30b0eca1
All of the following conditions are associated with an early systolic murmur, EXCEPT:
Aoic stenosis
Tricuspid regurgitation
Papillary muscle dysfunction
Small ventricular septal defect
0a
multi
Aoic stenosis
Medicine
null
140a19fc-a436-4fd0-9795-268f35ab2682
SI unit of Radioactivity is
Curie
Becquerel
Roentgen
Sievert
1b
single
SI unit - Becquerel Old unit - Curie
Radiology
null
b0a81f73-5fc2-4e40-8c7c-80b90262dfb7
All require hospitalization except
5% burns in children
10% scalds in children
Electrocution
15% deep burns in adults
0a
multi
null
Surgery
null
308b8f00-75b5-491b-9a84-ed68ece4dc46
SA node acts as a pacemaker of the hea because of the fact that it:
Is capable in generating impulses spontaneously
Has rich sympathetic innervations
Has poor cholinergic innervations
Generates impulses at the highest rate
3d
single
The sinoatrial (SA) node normally displays the highest intrinsic rate. All other pacemakers are referred to as subsidiary or latent pacemakers because they take over the function of initiating excitation of the hea only when the SA node is unable to generate impulses or when these impulses fail to propagate. There is a...
Physiology
null
53da0711-5b1c-4729-829f-0790bb8daec8
A 62-year-old diabetic patient presented with a history of progressive right-sided weakness of one-month duration. The patient was also having speech difficulty. Fundus examination showed papilledema. Two months ago, she also had a fall in her bathroom and struck her head against a wall. The most likely clinical diagno...
Alzheimer's disease
Left parietal glioma
Left MCA territory stroke
Left chronic subdural haematoma
3d
multi
null
Medicine
null
181d5cc0-a2b7-4302-a539-a966c913bee7
Which of the following is Calcivirus-
Hepatitis E
Hepatitis B
Hepatitis C
Hepatitis A
0a
single
Hepatitis A → Picorna Viridae (Single Stranded RNA) Hepatitis B → Hepadna Viridae (Double stranded circular DNA)* Hepatitic C → Flavivirus (single stranded RNA) Hepatitis D → Incomplete RNA virus (causes infection only in presence of Hepatitis B virus) Hepatitis E → Calcivirus (Single stranded RNA
Microbiology
null
c7fa5b72-9f2e-4eaa-a848-8063beac2f7f
Not seen in children is
Neuroblastoma
Retinoblastoma
Hepatoblastoma
Seminoma
3d
single
Seminoma, the most common GCT in adults, does not occur before 5 years of age. seminoma is considered a postpubeal tumor.
Pathology
Pediatrics, environment and nutrition
a88e7708-0106-45eb-a8aa-0189856b0793
Which group of anticancer drugs temozolomide belong to :
Oral alkylating agent
Antitumor Antibiotic
Antimetabolite
Mitotic Spindle Inhibitor
0a
single
Temozolomide is an alkylating agent that can be given orally.
Pharmacology
null
7a031a5a-48f3-4cdd-854b-3aca92473144
A patient with traumatic paraplegia due to injury of the thoracic cord of 'T3 level' is observed to have blood pressure f 210/120. What should be the initial management?
Subcutaneous LMWH
Steroids
Nifedipine
Normal saline / Dextrose
2c
single
Traumatic paraplegia is caused by a lesion of the spinal cord which occurs after a trauma, e.g. veebral fracture causing a puncture to the spinal cord. Any injury of the spinal cord may result in a condition known as autonomic dysreflexia (AD).. Autonomic dysreflexia can cause systolic blood pressure readings to increa...
Medicine
C.N.S
6b9c613b-b314-46d0-a352-857979c26821
The drug found to be beneficial in amyotrophic lateral sclerosis is :
Riluzole
Methylprednisolone
Hydroxyurea
None of the above
0a
multi
null
Pharmacology
null
093038dd-d6c1-49d9-864c-843be04a944f
All are true of the genetic code except ?
Degenerate
Universal
Punctuation
Non overlapping
2c
multi
C i.e. Punctuation
Biochemistry
null
880cc1ef-f8fc-45c0-a4fb-ce5fe81be66e
Therapeutic levels of lithium (in mecill) in a patient of acute mania is:
0.4–0.8
0.8–1.2
1.2–1.6
1.6–2.0
1b
single
null
Pharmacology
null
95265c95-9b0d-4b64-9fcf-2643b72e48aa
Wrong statement is -
Pulses are deficent in methionine
Cerels are deficient in lysine
Wheat deficient in threonine
Maize is deficient in tryptophan & leucine
3d
multi
Maize is deficent in in tryptophan and lysine. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 579
Social & Preventive Medicine
Nutrition and health
cf5faa3c-4e8b-4cbd-a52b-0d5aeed4fd62
Psammoma bodies are found in which of the following organs?
Stomach
Hea
Lungs
Thyroid
3d
single
Histologically, with the usual hematoxylin and eosin stain, calcium salts have a basophilic, amorphous granular, sometimes clumped appearance. They can be intracellular, extracellular, or in both locations. In the course of time, heterotopic bone may be formed in the focus of calcification. On occasion single necrotic ...
Pathology
null
dc5090a9-0718-41b0-b0af-d1cb3fb44f75
Preload is increased by -
Increased blood volume
Increased total peripheral resistance
Standing
Sitting
0a
single
Ans. is 'a' i.e.. Increase blood volume Preload (Degree of ventricular filling during diastole)o Cardiac preload is represented by volume of venous blood that distends the ventricle, i.e., venous return determines the preload. An increase in preload, i.e., increase in venous return results in a higher end-diastolic vol...
Physiology
Circulation: Cardiac Output, Venous Return
3d537990-81ce-473b-9a8d-f5098b32131c
Hanifin & Rajke is the diagnostic criteria for
Atopic dermatitis
Contact dermatitis
Uicaria
Erythroderma
0a
single
Ans. is 'a' i.e., Atopic dermatitis Hanifin and Rajka criteria is for diagnosis of atopic dermatitis. Diagnostic criteria (Hanifin and Rajka) Based mainly on clinical experience Major criteria Family history of atopy Chronicity Pruritus Typical morphology and distribution Minor criteria Dry skin Chelitis Elevated edge ...
Skin
null
2de9693c-515e-4152-a229-5e6c96848186
Nerve affected in trendenlenberg test is ?
Superior gluteal nerve
Inferior gluteal nerve
Obturator nerve
Pudendal nerve
0a
single
Ans. is 'a' i.e., Superior gluteal nerve
Surgery
null
9f822821-43a4-4366-836e-648ac297e054
Following predispose to the high risk of vulvovaginal candidiasis except
HIV
Hypeension
Pregnancy
DM
1b
multi
Several potential risk factors have been described, including the recent use of antibiotics and oral contraceptives, the presence of diabetes mellitus, dietary practices, gastrointestinal colonization by the organism, clothing and sanitary protection practices, sexual communicability of the organism, and HIV, DM, Ref g...
Physiology
All India exam
dc98be1c-09bb-4063-b2f1-690f2c2ea3e9
A 71-year-old woman comes to the office with a history of headaches, fatigue, and weight loss for 3 months. The headaches are new for her, and usually not very severe. Her jaw also hurts when she is chewing food. Two days prior, she had briefly lost partial vision in her left eye. There were no other neurologic symptom...
immune complex deposition
arteritis with giant cells
lymphocytic infiltration
type II muscle fiber atrophy
1b
multi
Temporal artery biopsy is required for definitive diagnosis of giant cell arteritis, because of the relatively nonspecific nature of the presenting symptoms, signs, and routine laboratory tests. The arteritis can be segmental, however, and great care must be taken in the pathologic assessment.
Medicine
C.N.S.
6350ebdb-0759-4056-bce0-bd35dc9f5943
The muzzle velocity of given firearm is
150 m/s
300 m/s
360 m/s
1500 m/s
0a
single
The revolver, which tends to have a low muzzle velocity of 150 m/s, is a sho barreled weapon with its ammunition held in a metal drum, which rotates each time the trigger is released.The muzzle velocity of pistols varies between 300 and 360 m/s.The rifle is a long-barreled shoulder weapon capable of firing bullets with...
Microbiology
All India exam
4407a8cd-6210-4bb0-a016-085ab9eeb310
MAC stands for?
Minimum alveolar concentration
Minimal analgesic concentration
Minimal anesthetic concentration
Maximum alveolar concentration
0a
single
Ans. is 'a' i.e., Minimum alveolar concentration Minimal alveolar concentration (MAC)* Most important measure of potency is minimal alveolar concentration (MAC). MAC is the lowest concentration of the anesthetic in pulmonary alveoli needed to produce immobility in response to a painful stimulus (surgical incision) in 5...
Anaesthesia
Fundamental Concepts
ccb4670b-95d4-4b9c-879e-bd30a72c7e4f
Acute onset of blurred vision and absent pupillary response with rapidly progressive descending muscular weakness manifesting as quadriparesis in an afebrile 20 year old male with preserved sensorium is -
Porphyria
Botulism
Polio
Diphtheria
1b
single
Ans. is tb' i.e., Botulism Remember these important points about Botulismo Acute onset of weakness in muscles innervated by cranial nerve with prominent bulbar palsy (4D's) i.e. -# Diplopia# Dysphonia# Dysphagia# Dysarthriao Descending symmetrical weakness occurs often leading to weakness,o Sensory' abnormalities are a...
Medicine
Toxicology
6740e137-8c0f-46d6-b638-bddd76af3cf6
All are affected in Graft-Versus host reaction
Skin
GIT
Liver
Lung
3d
multi
• GVHD affects skin (earliest organ), intestine and liver • Lungs are not affected in GVHD. For details see text.
Pathology
null
eb92f25f-29ec-4931-b26b-e76816b33c70
Vitamin D is maximum in -
Milk
Fish fat
Eggs
Cod liver oil
3d
single
Cod liver oil But overall Richest source is Halibut liver oil Ref: Park 25th edition Pgno : 653
Social & Preventive Medicine
Nutrition and health
768ac204-670b-4707-899d-e030964e00ee
All of the following drugs are used in emergency management of acute hyperkalemia except:
Calcium gluconate
Salbutamol
Glucose-Insulin
Intravenous magnesium sulphate
3d
multi
Treatment of Hyperkalemia: IV Ca gluconate Insulin drip Salbutamol/ nebulization IV Furosemide Hemodialysis
Pharmacology
Hypeension, Arrhythmias, Dyslipidemia
075c6aab-1ef0-43c9-926f-7770b3ed4507
A female presents with significant blood loss due to post-partum haemorrhage (PPH). What would be the shock index (HR/systolic BP)?
0.3-0.5
0.5-0.7
0.7-0.9
0.9-1.1
3d
single
Shock index = heartrate/systolic BP Normal = 0.5–0.7 If it becomes 0.9–1.1 it indicates massive blood loss and need for intensive resuscitation.
Gynaecology & Obstetrics
null
4551e60a-c5c8-4827-a768-bebabf6cd36b
Subnuclear cytoplasmic vacuolization is seen in which stage of menstural cycle ?
Proliferative phase
During mensturation
Secretory phase
None
2c
multi
Ans. is 'c' i.e., Secretory phaseSubnuclear cytoplasmic vacuolization is seen in early secretory phase.Histological features in secretory phasei) Basal location of gland cell nuclei (Post-ovulation day 5-6 and later in cycle).ii) Subnuclear cytoplasmic vacuolization (early secretory phase).iii) Serated glandular config...
Physiology
null
6a772c13-d3fa-4854-a2a2-b7aa1bc1f431
what is the root value of phrenic nerve?
C3,4,5
C2,3,4
C4,5,6
C5,6,7
0a
single
* Phrenic nerve (C3,C4,C5)- It descends in front of scalenus anterior muscle . * Descends down to enters thorax where it lies between subclan vein(in front) and subclan aery lies behind it . * Fuher it descends in front of hilum of the lungs (whereas vagus nerve descends behind the hilum of lungs) * It is mixed nerve s...
Anatomy
Bronchopulmonary Segments, Embryonic veins
3a2f6c05-c606-48c0-9e66-cef8629b45a7
Antibiotics are indicated in which type of psoriasis?
Guttate
Pustular
Chronic plaque psoriasis
Erythrodermic psoriasis.
0a
single
Ref: Rook's Textbook of DermatologyExplanation:Guttate psoriasis (Eruptive psoriasis)Presents as shower of small psoriatic lesions, appearing more or less generally over the body, particularly in children and young adults, after acute streptococcal infections.Guttate psoriasis is classically triggered by a bacterial in...
Skin
Psoriasis
ae1fabce-4c79-470a-adac-4250080d5761
A patient has Bullous Lesion; on Tzank smear -
Langerhans ceils are seen
Acantholysis
Leucocytosis
The absence of melanin pigment
1b
single
Ans-BTzank smearo It is done for vesiculobullous disorders.o A small, early, uninfected lesion should ideally be selected. The roof of the blister is removed with scissors, and the base of the blister gently scraped with a blunt scalpel so as not to produce bleeding. The material obtained is spread thinly on a glass sl...
Unknown
null
1e6f0f44-24d6-4489-bb68-ce87af037ecc
Which of the following has propensity to metastasize through lymph nodes -
Alveolar rhabdomyosarcoma
Osteosarcoma
Both
None
0a
multi
Alveolar rhabdomyosarcoma is a type of rhabdomyosarcoma characterized by its appearance, which is similar to the alveoli of the lungs. It can be associated with a fusion protein between PAX3 and FKHR (now known as FOXO1). It can also be associated with PAX7-FKHR.Alveolar rhabdomyosarcoma (ARMS) typically affects all ag...
Pathology
General pathology
3a069379-2b20-4c7e-8392-1c8c61dfa9ce
Key symptom in alcohol withdrawal syndrome is:
Sleep disturbance
Visual hallucinations
Tremors
Delirium
2c
multi
Ans: C. TremorsKey symptom - Tremor.Withdrawal SyndromesSubstanceFeaturesOpioidYawningdeg, Insomnia, Dysphoric moodWater loss from different orificesdeg (Lacrimationdeg, sweatingdeg, diarrheadeg, vomiting, Increased vitalsdeg (BP, Pulse, RR, Temperature)degPupillary dilation, piloerectiondegAlcoholHang over (MC)degHall...
Psychiatry
null
7bcc73e5-49fb-44cd-ad92-0097c9769dc0
Which of the following is not used as hemostatic agent during furcation repair?
Ca(OH)2
Ferric sulphate
Calcium sulphate
Collagen
1b
single
null
Dental
null
15563c94-f3b0-44c5-87d4-54f9cdfd3d2b
Bonded retainers are popular in which area of dentition?
Lower anteriors
Lower posteriors
Upper anteriors
Upper posteriors
0a
single
null
Dental
null
694d3e8f-b57c-405d-89e6-8e1fcb4f2ba7
Figure of 8 in chest X-ray is seen in –
Ebstein anomaly
Total anomalous pulmonary venous connection (TAPVC)
Tetrology of fallot
Transposition of great vessels
1b
multi
Snowman's sign or figure of 8 sign is seen in supracardiac TAPVC.
Radiology
null
a37df1c3-204e-4341-abf3-fb23433d0438
Parafollicular 'C' cells develop from:
Parafollicular 'C' cells develop from:
Second branchial cleft
Ultimobranchial body
Third branchial pouch
2c
single
C. i.e. Ultimobronchial body
Anatomy
null
1b8960e0-a53c-434d-bbdc-c8b0efbe02c6
AMPLE history includes all of the following except;
Allergy.
Personal history.
Last meal.
Medication
1b
multi
AMPLE history is a useful mnemonic for this purpose: Allergies Medications currently used Past illnesses/Pregnancy Last meal Events/Environment related to the injury
Surgery
null
d6c0c080-55a0-49db-bfcb-acc26dfa26f8
Which of the following enzymes require Vitamin C for their activity?
Procollagen proline hydroxylase
Procollagen amino peptidase
Procollagen carboxyl peptidase
Lysyl oxidase
0a
single
Vitamin C plays the role of a coenzyme in hydroxylation of proline and lysine while protocollagen is converted to collagen  (i.e.  post-translational modification). The hydroxylation reaction is catalysed by lysyl hydroxylase  (for  lysine)  and prolyl  hydroxylase (for  proline).
Biochemistry
null
a6283983-21e4-4d84-8aba-ed6a1ad6d33f
The mechanism of action of cephalosporin is:
Interferes with cell wall synthesis
Inhibition ol DNA gyrase
Inhibition of protein synthesis
Inhibition of DMA polymerase
0a
multi
Ans: A (Interferes with cell wall synthesis) Ref: Goodman & Gilmans The Pharmacological Basis of Therapeutics, 12th ed, 2011. Pg 1479, 1493: Basic and Clinical Pharmacology by Katzung, 2012, 12th ed, Pg 792Explanation:Cephalosporin inhibits bacterial cell wall synthesis.Its mechanism of action is similar to penicillin ...
Pharmacology
Penicillin & Cephalosporin
ef888510-5f56-4297-8a12-28f3fc3b0371
Reduced FEV 1, Normal FVC and FEV 1/FVC ratio less than 0.7 .which is reversible with bronchodilator s is consistent with
Bronchial Asthma
Hypersensitivity penumonitis
Sarcoidosis
Polyaeritis nodosa
0a
single
In Asthma FEV1(forced expiratory volume in 1 second), FVC(forced vital capacity, is the total volume exhaled), FEV1/FVC decreases. To daignose Asthma: Compatible clinical history plus either : 1)FEV1>12% increase following administration of a bronchodilator or glucocoicoids. 2)FEV1>15% decrease after 6min of exercise 3...
Medicine
Respiratory system
1c6a56ac-46fd-451b-ac07-7a3364abb2e8
A patient married for 3 years, unable to conceive, has regular menstrual cyclesHusbands semen analysis is normal and so is his hormonal profile What is the right time in menstrual cycle to do endometrial biopsy for infeility:-
12-14 days
17-19 days
20-22 days
3-5 days
2c
single
Endometrial biopsy is best done on 21st - 23rd day of the cycle. Evidences of secretory activity of the endometrial glands in the second half of the cycle give not only the diagnosis of ovulation but can predict the functional integrity of the corpus luteum. Luteal Phase Defect- Lag of 2 to 4 days in observed/expected ...
Gynaecology & Obstetrics
Normal Menstruation, Abnormal Menstruation, Menopausal Physiology and forsight of conception
786921b8-a941-4eb0-8c38-ebbf097c2bf9
Which of the following is not a feature of RPGN?
Oliguria
Edema
Hypeension
Rapid recovery
3d
single
Patients with RPGN presents with features of glomerulonephritis such as hematuria, edema and hypeension in association with a rapidly progressive loss of renal function. When untreated these patients rapidly develop end stage renal disease and death can occur within weeks to months. Reference: Robbins Pathologic Basis ...
Medicine
null
28e8ae2f-b81b-4c7f-a9d8-f65ad9df49b8
Bed strength at CHC:
6-Apr
10
30
50
2c
single
Community Health Centre (CHC) Secondary level of health care. Located for population of 1,20,000 in plains. Located for population of 80,000 in hilly areas. Staff at CHC : 46-52 Acts as referral unit for 4 PHCS. Bed strength : 30
Social & Preventive Medicine
null
51af9d9e-1ad2-442b-9aa6-0b88d289a079
Most common cytochrome associated with metabolism of drugs is ?
CYP3A4/5
CYP2D6
CYP2C8/9
CYP2Cl.9
0a
single
Ans. is 'a' i.e., CYP3A4/5 Cyp 3 A 4/5 carryout biotransformation of largest number (nearly 50%) of drugs.
Pharmacology
null
1d20c2ee-2f93-4cf3-9ebb-3c5d8117abf6
Which premolar resembles a canine
Maxillary 1st premolar
Mandibular 1st premolar
Maxillary 2nd premolar
Mandibular 2nd premolar
1b
single
Mandibular 1st premolar resembles canine from buccal aspect and it has almost rudimentary lingual cusp which further makes it canine alike.
Dental
null
6f420fb2-0c31-4130-b436-ed0cf8f43d75
The alveoli are normally kept dry by the:-
Macrophages
Surfactant
Negative intrapleural pressure
High pCO2 in the alveoli
1b
multi
Surfactant is a mixture of dipalmitoyl phosphatidyl choline, other proteins & lipids. Role in keeping alveoli dry :- 1. The lipids in the alveolus 2. In the absence of surfactant, the unopposed surface tension in the alveoli would produce a force that greatly ors transudation of fluid from blood into alveoli. Note Fact...
Physiology
Respiratory System Pa 1
f481dd2a-ab51-4602-b993-7063d6816e9c
In which of the following, virus is shed in stool?
Herpangina
Influenza
Varicella
Smallpox
0a
multi
Herpangina: Respiratory viral shedding can persist for up to 3 weeks and in the stool for up to 8 weeks. Patients are most contagious at this stage. Influenza: People with flu can spread it to others up to about 6 feet away. Most experts think that flu viruses spread mainly by droplets made when people with flu cough, ...
Microbiology
null
76bd3887-86fe-4529-a5e7-0c178a1d4ab8
Which of the following clinical signs is not associated with acute appendicitis?
Pointing sign
Rovsing's sign
Cullen's sign
Obturator sign
2c
single
Ans. c (Cullen's sign) (Ref. Bailey and Love 26th/pg. 1203; box 71.4)Signs to elicit in appendicitisClinical signs of Acute Pancreatitis# Pointing sign# Cullen's sign# Rovsing's sign# Grey Turner's sign# Psoas sign# Fox sign# Obturator sign ACUTE APPENDICITIS# Acute appendicitis is relatively rare in infants, and becom...
Surgery
Vermiform Appendix
3cc9c16b-2271-40ba-828c-d7b8de54f1cc
Rapid fluid resuscitation of the hypovolemic patient after abdominal trauma is significantly enhanced by which of the following?
Placement of long 18-gauge subclavian vein catheters
Placement of percutaneous femoral vein catheters
Bilateral saphenous vein cutdowns
Placement of short, large-bore percutaneous peripheral intravenous catheters
3d
single
Rapid fluid administration is often the key to successful trauma resuscitation. Some of the important factors affecting the rate of fluid resuscitation include the diameter of the intravenous tubing, the size and length of the venous cannulae, the fluid viscosity, and the site of administration. According to Poiseuille...
Surgery
Trauma
7b63f051-afa8-45e9-9e56-f0c1b56dac9e
A 16 year old girl was brought to the psychiatric emergency after she slashed her wrist in an attempt to commit suicide. On enquiry her father revealed that she had made several such attempts of wrist slashing in the past, mostly in response to tril fights in her house. Fuher she had marked fluctuations in her mood wit...
Borderline personality disorder
Major depression
Histrionic personality disorder
Adjustment disorder
0a
single
A i.e. Borderline Personality DisorderSchizophrenia can easily be ruled out by absence of disorganized speech, disorganized behaviour (or catatonia), delusions, hallucinations, & negative symptoms (ex blunt affect) for more than 6 months & leading to social / occupational dysfunction.
Psychiatry
null
c07923c3-0e53-4314-9b5a-dfd6f92c52a3
True about active immunity
Less effective
Can be given in immunodeficient state
Immunological memory present
No lag period
2c
multi
When B cells and T cells are activated by a pathogen, memory B-cells and T- cells develop, and the primary immune response results. Throughout the lifetime of an animal these memory cells will "remember" each specific pathogen encountered, and are able to mount a strong secondary response, if the pathogen is detected a...
Microbiology
Immunology
1f7578c8-0e54-426f-aba1-67742a84b51c
Vasopressin decreases the volume of urine primarily by causing :
Decrease in glomerular filtration rate
Decrease in renal blood flow
Decrease in water permeability of descending limb of loop of Henle
Increase in water permeability of collecting duct cells
3d
single
null
Pharmacology
null
8bb86f81-2b79-4c62-9b02-716612b7e4e1
All of the following cell types undergo cell division, EXCEPT:
Pericyte
Cardiac muscle cell
Smooth muscle cell
Satellite cell of skeletal muscle
1b
multi
Myocyte cell division in the human hea ceases a few weeks after bih. Thereafter, enlargement of the hea is as a result of cell hyperophy or the laying down of collagen in the extracellular space. DNA turnover is almost undetectable except in pathologic states. Approximately 20% of myocytes in the human hea have two nuc...
Physiology
null
bcc7abc2-8bf9-4bc9-aff6-555b85c012b3
1st Symptom to go with treatment of schizophrenia
Apathy
Anhedonia
Auditory hallucination
Paucity of thoughts
2c
multi
C i.e. Auditory hallucinations
Psychiatry
null
9eff2e40-1455-4396-aa44-df6f94128b0e
Louis Pasteur is associated with all except -
Vaccination of small pox
Germ theory
Pasteurization
Vaccination of rabies
0a
multi
The development of microbiology as a scientific discipline dates from Louis pasteur (1822-95). He introduced techniques of sterilisation and developed the steam sterilizer,Hot air oven and auto clave. He also established the differing growth needs of different bacteria and contributed to the knowledge of anthrax,chicke...
Microbiology
general microbiology
8e31ce90-cfb7-4059-bafe-e7aaa1ed08b6
In post-term pregnancy, there is increased risk of all except
Postpaum hemorrhage
Meconium aspiration syndrome
Intracranial hemorrhage
Placental insufficiency leading to fetal hypoxia
0a
multi
Post maturity DOES NOT put mother at risk.Increased morbidity may occur due to hazards of induction. Post term pregnancy causes an increased risk of placental insufficiency due to placental ageing,meconium aspiration and intracranial hemorrhage. (TB of obstetrics DC DUTTA 8th edition pg 374)
Gynaecology & Obstetrics
Abnormal labor
6a1ea4bf-28e4-41b6-8a95-8e1ea2b97c68
According to AJCC 8th edition, staging of 2 cm size pancreatic cancer if it involves poal vein in:
T1
T2
T3
T4
0a
single
8th AJCC(2017) TNM Classification of Pancreatic cancer Tis Carcinoma in situ T1 Tumor limited to pancreas upto 2 cm in greatest dimension T1a : Tumor <= 0.5 cm in greatest dimension T1B: Tumor > 0.5 cm but <= 1 cm in greatest dimension T1c : Tumor > 1 cm but <= 2 cm in greatest dimension T2 Tumor limited to pancreas > ...
Surgery
Pancreas
ae38b489-1ba0-4dea-bd9a-3a683651d95a
The following are related to fetal erythropoiesis except :
In the embryonic phase, the erythropoiesis is first demonstrated in the spleen
By 20th week, the liver becomes the major site of erythropoiesis
Near term, the bone marrow becomes the major site of erythropoiesis
At term 75-80% of haemoglobin is fetal type (HbF)
0a
multi
Primitive hematopoiesis and vasculogenesis first occur in the yolk sac followed by liver and finally bone marrow, leading to the production of blood and vessels respectively Blood islands, clusters of primitive erythrocytes surrounded by endothelial cells, arise from the extraembryonic mesoderm in the yolk sac Hematopo...
Gynaecology & Obstetrics
General obstetrics
571af714-578c-4f10-bfc8-a058f7fbed88
First clinical sign of Vitamin - A deficiency is:
Night blindness
Conjunctival xerosis
Bitot's spots
Keratomalacia
1b
single
All the ocular manifestations of Vitamin - A deficiency are collectively known as 'Xerophthalmia' (Dry Eye). - Xerophthalmia is most common in children aged 1-3 years. 'First clinical sign' of Vitamin - A deficiency: Conjunctival xerosis . 'First clinical symptom' of Vitamin - A deficiency: Night blindness. Conjunctiva...
Social & Preventive Medicine
Vitamins and Nutritional Deficiencies
e947a1fe-dc52-4f2e-bcc9-cdd095f7b6a4
Most common cause of umbilicus does not separate at age of 2 years
Raspbery tumour
Leukocyte adhesion deficiency
Patent urachus
Umblical granuloma
1b
single
Ans. is 'b' i.e., Leukocyte adhesion deficiency
Surgery
null
db23aede-4b57-40ec-829d-2ff5f2b11531
The drug of choice for prevention of seizures in a patient with severe preeclampsia is :
Phenytoin
Magnesium sulphate
Diazepam
Nifedipine
1b
single
null
Pharmacology
null
472c4566-3ac9-452f-a609-7d18544d3a08
Left bundle branch block (LBBB) on ECG can suddenly develop in all of the following except
Acute MI
Ashman syndrome
Hypokalemia
Hyperlcalernia
2c
multi
null
Medicine
null
91d11336-a972-45f0-8480-9dadf9f6d95c
Various factors are involved in inflammation. Which among the following is NOT a mediator of inflammation?
Tumour Necrosis Factor (TNF)
Interferon
Myeloperoxidase
Prostaglandins
2c
single
Tumour necrosis factor, interferon, prostaglandins are mediators of inflammation. The protein MPO is a marker of azurophil granules. MPO reacts with H2O2, formed by the NADPH oxidase, and increases the toxic potential of this oxidant. Through oxidation of chloride, tyrosine, and nitrite, the H2O2-MPO system induces for...
Pathology
null
61b18931-f30d-4d83-873c-a6ac84462364
In Against-the-rule astigmatism:
Veical meridian is more curved than the horizontal
Horizontal meridian is more curved than the veical
Both meridia are equally curved
None of the above
1b
multi
Ans. Horizontal meridian is more curved than the veical
Ophthalmology
null