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135
ae29e3d1-085f-4e58-935d-893261415feb
True about hepatitis A viurs ?
Causes cirrhosis
Helps HDV replication
Common cause of hepatitis in children
Causes chronic hepatitis
2c
multi
Ans. is 'c' i.e., Common cause of hepatitis in children HAV is the most common cause of hepatitis in children. HAV does not cause chronic hepatitis or cirrhosis. HBV (no HAV) helps in HDV replication.
Microbiology
null
4cf53dd4-1047-472f-877b-cb9a62d360b9
The following tests may be useful in the assessment of a patient with sarcoidosis
Chest X-ray
ACE
Serum calcium
All of the above
3d
multi
Investigations in Sarcoidosis Lymphopenia is characteristic and liver function tests may be mildly deranged. Hypercalcaemia may be present (reflecting increased formation of calcitriol - 1,25-dihydroxyvitamin D - by alveolar macrophages), paicularly if the patient has been exposed to strong sunlight. Hypercalciuria may...
Medicine
Immune system
1d4df690-1700-4b66-8674-1a7b53fdca4c
which of the following SSRI is hea safe
escitalopram
clomipramine
fluoxetine
amitriptilline
0a
single
SSRI * IMPOANCE Most widely prescribed antidepressant * MECHANISM Specifically acts on serotonin transpoers and increases serotonin in synapse. DRUGS FLUOXETINE FLUVOXAMINE DAPOXETINE CITALOPRAM ESCITALOPRAM ESCITALOPRAM SERALINE PAROXETINE USE FLUOXETINE=============CHILDHOOD DEPRESSION FLUVOXAMINE===========OCD DAPOX...
Psychiatry
Pharmacotherapy in psychiatry
40a9c6c3-7798-4d54-9c70-45f3f4c4e01f
Choose the appropriate lettered structure in this MRI scan showing a transaxial section through the head. Which structure may be obliterated by a pituitary tumor?
A
B
C
D
2c
single
(c) The suprasellar cistern can be obliterated by a pituitary tumor.
Anatomy
Head & Neck
6a8aca69-0485-470a-bbde-8f452a4b4674
Pedigree Chart -
Used for growth monitoring.
To assess side effect during chemotherapy
Used to see genetic transmission.
To assess developmental delay in infant
2c
single
Ans. is 'c' i.e., Used to see genetic transmission Pedigreeo Provide graphic depiction of a family structure medical history'.o Person providing information is formed as pro band,o Special symbol is used for each designation,o Three generation pedigree should be made.o Closer the relationship of proband to the person, ...
Pediatrics
Genetics And Genetic Disorders
d698059f-551e-4984-a760-419061c33ba0
True about cornea –a) Power is 43 Db) Majority of refraction occur at air – tear interfacec) With the rule astigmatism is present because vertical meridian more steep than horizontal meridiand) Spherical structuree) Refractive index 1.334
ab
bc
abc
bcd
2c
multi
It has already been explained in this chapter that maximum refraction occurs from the anterior surface of the cornea (at the air-tear interface) because the difference between refractive index of two medium is maximum at this site. The air has a refractive index of 1.00 and cornea has refractive index 1.376, the differ...
Ophthalmology
null
15446fe5-2559-40c2-8fa1-66656fa0991b
Following is/ are the clinical feature/ s of lepromatous leprosy -
Leonine facies
Loss of libido and impotence
Saddle nose
All the above
3d
multi
Ans. is 'd' i.e., All the above Important clinical features oflepromatous leprosyo Diffuse erythema, tingling, nasal stuffiness or ep is tax is are earliest manifestations.o Nodules with predeliction for external ears,o Madarosis (loss of eye lashes and eye brow s),o Saddle nose (Collapse of nasal bridge) and perforati...
Skin
C. Mycobacteria
830eab55-09c4-49dc-9d9e-a48aef8c355e
Causes of macrocephaly includes?
Galactosemia
Weaver syndrome
Soto's syndrome
All of the above
3d
multi
Causes of Megalencephaly Lysosomal storage diseases: Gangliosidosis, MPS Carbohydrate disorder: Galactosemia Aminoacidurias: Maple Syrup urine disease, Glutaric aciduria type-1 Neurogenerative diseases: Alexander disease, Canavan disease, Metachromatic leukodystrophy Neurocutaneous diseases: Neurofibromatosis, Tuberous...
Anatomy
General anatomy
cb346e41-7afd-4e14-8a96-779b317a8a5b
The maximum dose of isotretinoin should not exceed
30-60mg/kg
60-90 mg/kg
90-120 mg/kg
120-150 mg/kg
3d
single
Oral isotretinoin duration of treatment varies according to dose but post-therapy relapse is minimized by treatment courses that amount to the total of 120-150 mg/kg Ref Harrison 20th edition pg 1233
Dental
All India exam
45e01978-7c85-4024-83b1-fb325916e855
Which of the following is feature of reticulocyte?
Constitute 10% of the red cells
No nucleus
Smaller in the size than RBCs
Mature in lymph nodes
1b
multi
Reticulocytes are non-nucleated spherical cells bigger than normal RBCs and are polychromatic (having a blue color) d/t the presence of free ribosomes & RNA. They are identified with supravital staining. Best stain to identify them is new methylene blue.
Pathology
Hematopoeisis: Basic concepts
d3bd91f7-e48a-4873-9e26-75dc562869c8
Nanotechnology has found tremendous application in the diagnosis of cancers because of all of following advantages, except
Nanocrystals exibit bright, photostable fluorescence
Nonocrystals have a narrow spectrum wavelength
Peak spectrum wavelength is tunable
Nanocrystals exhibit a narrow difference between their excitation and emission peak spectra
3d
multi
Ans'd. Nanocrystals exhibit a narrow difference between their excitation and emission peak spectra
Pathology
null
24c618da-ec9c-48b1-b8c6-68052496a293
Complications of sphenoid sinus surgery are all except:
CSF leak
Optic nerve injury
Lateral rectus palsy
Orbital emphysema
3d
multi
(d) Orbital emphysema(Ref. Cummings, 6th ed., 778)Orbital complications will follow maxillary, ethmoid and frontal sinus surgeries due to close proximity.
ENT
Nose and PNS
806d1d4d-a49d-470f-a731-babad4a4d583
Erosive ahritis is seen in all, except
SLE
Gout
Osteoahritis
Old age
0a
multi
Ref Semantischolar.org
Medicine
Immune system
b7074fe0-aa45-4419-b2cf-e6449f94eb39
A 9 1/2 -year-old girl presents to your office with an approximately 1 1/4 -cm nodule in her neck, just to the left of the midline and below her cricoid cartilage. It is nontender and moves when she swallows. It has been enlarging over the last several months and was not seen by the pediatrician at her 9-year-old check...
Reactive viral lymphadenopathy
Papillary thyroid cancer
A brachial cleft cyst
A follicular adenoma of the thyroid
1b
multi
While reactive lymphadenopathy is by far the most common cause of neck masses in children; a lymph node should not move with deglutition and is more likely to be tender. A branchial cleft syst should be more lateral and the thyroglossal duct cyst should be higher and in the midline (although they can sometimes present ...
Surgery
Plastic & Reconstructive Surgery
91ec5518-373b-4a7e-9246-d7a72ba7640c
Site of transplantation in Islet cell transplant for Diabetes mellitus is
Skin
Injected into the poal vein
Liver
Pelvis
1b
single
The islets are then purified from the dispersed tissue by density-gradient centrifugation and can be delivered into the recepient liver (the preferred site for transplantation) by injection into the poal vein Ref: Bailey and love 27th edition Pgno :1552
Anatomy
General anatomy
77586db1-ffb6-446d-aff1-796d79223559
A young pt presents with jaundice. Total bilirubin is 21, direct is 9.6, alkphosis 84 KA units. Diagnosis is:
Hemolytic jaundice
Viral hepatitis
Chronic active hepatitis
Obstructive jaundice
3d
single
Answer is D (Obstructive jaundice): Direct bilirubinemia (conjugated birirubin > 15% of total bilirubin) along with high serum alkaline phosphatase (6-7 times normal) suggests the diagnosis of obstructive jaundice. AffirghnfeAre Total bilirubin (mg/di) 0.3 to 1.0 21.0 Direct bilirubin is 45% of total bilirubin Conjugat...
Medicine
null
7ef8af5c-38ee-4a77-9663-1be485a9aeaa
A 20 year old man presents with swelling of left lower limb and hydrocoele. All of the following may be the causative agent EXCEPT:
Brugia malayi
Brugia timoria
Wuchereria bancrofti
Onchocerca volvulus
3d
multi
Ans. (d) Onchocerca volvulusRef: Diagnostic medical parasitology 3rd/275, Park 19th /221* Onchocerca volvulus results in river blindness and subcutaneous nodules.* "Lymphatic filariasis" covers infection with three closely related nematode worms - W.Bancrofti, B. Malayi and B. timoria.* All three infections are transmi...
Microbiology
Mycology
ab157e1b-f77c-4c77-904f-c05e20321dad
Very high intraocular pressure, veically oval mid-dilated pupil and shallow anterior chamber is seen in:
Primary open angle glaucoma
Acute primary angle closure glaucoma
Malignant glaucoma
Pupillary block glaucoma
1b
multi
Ans. B: Acute primary angle closure glaucoma
Ophthalmology
null
56a69b5d-6782-4fd2-81a4-bba439c8fcd6
Which of the following vaccines can be used in pregnancy in normal circumstances?
MMR vaccine
Varicella vaccine
Influenza trivalent vaccine
Hepatitis A vaccine
2c
single
Pregnancy is not a contraindication or precaution for Influenza trivalent vaccine. This vaccine is recommended for women who will be pregnant during influenza season. Influenza live attenuated vaccine is contra indicated. Must Know - Principle: Live-virus vaccines are contraindicated during pregnancy because of the pos...
Social & Preventive Medicine
null
5729d11a-d2a9-4340-b3d5-b16a80b99610
True statement about listeria:
Gram negative bacillus
Motile by peritrichous flagella
Commonest cause of community acquired meningitis
Only one serovar is known
1b
multi
Ans. is. 'b' i. e., Motile by peritrichous flagella
Microbiology
null
4d31c7e1-c3c6-40a4-8b36-0bbbc598757c
Acute graft rejection occurs within?
Few minutes
Few hours
< 6 months
6-12 months
2c
single
Hyperacute rejection: type 2 HSR, happens over span of few minutes to hours. Eg: kidney transplant Acute rejection: Few weeks to months(< 6 months) Chronic rejection: After 6 months. Graft vs host disease (Runt Disease): Acute GVH: < 100 days Chronic GVH: > 100 days
Pathology
FMGE 2019
c8ae46e5-eb0a-4864-bc20-5179d0891e92
The protein that carries iron from the gut to the body tissues is called
Ferritin
Haemosiderin
Myoglobin
Transferrin
3d
multi
null
Pathology
null
d64a63bf-c476-4043-9b1c-05bf5e2628c1
After an endoscopy a technician kept the instrument for sterilization. Which of the following agent is used for sterilization of fibre optic instruments?
Glutaraldehyde
Chlorine
Autoclave
Phenol
0a
single
Glutaraldehyde, which has two reactive aldehyde groups, is 10 times more effective than formaldehyde and is less toxic. It denatures proteins and nucleic acids. Both proteins and nucleic acids contain essential -NH2 and -OH groups, which are the main sites of alkylation. In hospitals, it is used to sterilize respirator...
Microbiology
null
be10ec1b-8d6e-43a1-9043-7ab77343f3f2
Cytokinee are secreted in sepsis in and systemic inflammatory response syndrome (SIRS) by:
Neutrophils
Adrenal
Platelets
Collecting duct
0a
single
ref Harrison 18/e p2223_2225 , Robbins 7/e p202 Cytokines are the peptide mediators or intercellular messangers which regulate immunological, inflammation,reparative host response.they are produced by widely distributed cells like macrophages ,monocytes, lymphocytes, platelets,fibroblast, endothelium,stromal cells etc....
Anatomy
General anatomy
4f35422d-7907-4a4e-a2e3-43484a81dd9c
Necrotizing lymphadenitis is seen in:
Kimura disease
Kikuchi Fujimoto disease
Hodgkin disease
Castelman disease
1b
single
Kikuchi Fujimoto disease Or histiocytic necrotizing lymphadenitis It is Benign and self-limited disorder in young individuals characterized by regional cervical lymphadenopathy with tenderness Accompanied with mild fever and night sweats Diagnosed on the basis of an excisional biopsy of affected lymph nodes which shows...
Pathology
Auto Immune Disorders Introduction
873a4e24-5786-4626-85a8-14e87015b7a5
Enucleation of the eyeball is contraindicated in
Endophthalmities
Panophthalmities
Intraoccular tumours
Painful blind eye
0a
multi
Endophthalmities is treated by intravitreal injection of antibiotics. If not managed and removal of eye of eye is indicated.we should go for evisceration. This is because the outer coats of the eyeball are not involved and hence we should not remove it. Also it is more convenient to put aificial eye then orbital implan...
Ophthalmology
Diseases of orbit, Lids and lacrimal apparatus
3ee93576-d484-4bff-9171-c3375cd5428a
Colostrums has in compared to normal milk -
Decreased K
Decreased Na
Increased proteins
Increased calories
2c
single
Colostrum contains a high concentration of proteins as compared to normal milk.REF.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE.Editon-21.Page no.-491
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics
cef4da9b-e2e4-4f6e-a3f2-7f3b75916ee3
The prognosis of rhabdomyosarcoma is likely to be poor if the site of the tumor is ?
Orbit
Paratesticular
Extremity
Urinary bladder
2c
single
Ans. is 'c' i.e. Extremity Rhabdomyosarcomas of the extremities have alveolar histology which is associated with aggressive tumor biology. Also know RMS is the most common malignant tumor of the soft tissues in infants and children. MC site is head & neck region Among head & neck, orbit is the most common site.
Surgery
null
13d1a16b-7679-4da4-9ee1-c2cc3a7ce60b
Pipkin classification is used for
Acetabular fractures
Pelvis ring fracture
Femoral head fracture
Femoral shaft fracture
2c
single
COMMON FRACTURES CLASSIFICATION FRACTURECLASSIFICATIONOpen fracturesGustilo & Anderson Supracondylar Humerus Galand ( based on displacement )Proximal Humerus Neer ( 4 pa fractures )Distal Radius Frykman , FermandezPelvis Young & Burgess, TileFemoral head Pipkin's classificationFemoral neck ( Pediatric )Delbet classific...
Orthopaedics
All India exam
9baf28d2-adec-4f9c-bdef-818da8763755
Osteoarthritis does not affect:
Knee joint
Hip joint
Interphalangial joint
Metacarpophalangial joint
3d
single
Ans: d (Metacarpophalangeal joint)Ref: Maheshwari Ortho, 3rd ed, p. 252 & Harrison, 15thed, p. 1990
Orthopaedics
Arthritis
69138b67-5fda-4a5b-947e-95923bbc535f
Most common viral cause of acquired aqueductal stenosis is ?
Rubella
Mumps
Toxoplasma
Enterovirus
1b
single
Out of the given options, only mumps and toxoplasma cause aqueductal stenosis. Toxoplasma is not a virus. Hence, the answer is mumps.
Pediatrics
null
507a0ca8-f93b-4cbe-b970-efb650197231
Pulsatile GnRH is used for managing:
Precocious puberty
Fibroid
DUB
Anovulatory infertility
3d
single
Ans. is d, i.e. Anovulatory infertilityPulsatile GnRH is used for:* Ovulation induction (in managing anovulatory infertility)* Delayed, puberty
Gynaecology & Obstetrics
Physiology & Histology
32dd536f-b070-4428-af6e-b5925aaa9de6
The regional aerial resistance of the mesentery and kidney vessels is reduced by
Dopamine
Dobutamine
Nor adrenaline
Isoprenaline
2c
single
In hyperdynamic sepsis, the peripheral aeriolar tone and BP are low but the cardiac output is often high; therefore the vasoconstrictor noradrenaline (norepinephrine) is appropriate to restore BP, usually at the price of some reduction in cardiac output.In most cases, a vasoconstrictor such as noradrenaline (norepineph...
Medicine
C.V.S
ae63bedc-1ec2-4370-af64-0bf943a003a7
All true about pisiform, except Manipal 11
Last carpal bone to ossify
Attached to flexor carpi ulnaris
Can be seen on newborn X-ray
It is a sesamoid bone
2c
multi
Ans. Can be seen on newborn X-ray
Forensic Medicine
null
0e7bbb2e-7820-4b9f-bf7c-4445a12a3292
Which of the following is an indication for using mifepristone?
Ectopic pregnancy
Fibroid uterus
Molar pregnancy
Habitual aboion
1b
single
Mifepristone, also known as RU486, is an antiprogestin that has been used for treatment of leiomyomas. Mifepristone diminishes leiomyoma volume by approximately half and it is effective in improving symptoms. Other uses of mifepristone: For termination of early pregnancy For emergency postcoital contraception Endometri...
Gynaecology & Obstetrics
null
4a005936-2b64-4b7e-b523-f868f4ec1efb
After passing his physical exam, a 19 year old army recruit gives urine and blood samples for fuher testing. Serum analysis yields elevated ALT, HBsAg, Anti-HBc, HBeAg, and bilirubin. All other values are normal. Which of the following is the hepatitis B status of this recruit?
Asymptomatic carrier
Chronic active carrier
Fulminant hepatitis B
Recovered from acute self-limited HBV
1b
multi
The presence of elevated ALT, HBsAg, anti-HBc, HBeAg, and bilirubin all point to active hepatitis B. An asymptomatic carrier does not have elevated ALT and bilirubin. The absence of findings on physical examination rules out fulminant hepatitis B. Recovery from acute self-limited HBV is associated with the presence of ...
Microbiology
null
c8398700-b266-44dd-a502-1460e95711c3
Which of the following organs does not show pale infarct?
Lung
Hea
Kidney
Spleen
0a
single
Pale infarcts are typically seen in hea, kidney and spleen. Red infarcts principally occur in organs with dual blood supply such as lungs, or in those organs with extensive collateral circulation such as brain and small intestine. In both types of infarcts, infarcted area shows coagulative necrosis, but in red infarct ...
Pathology
null
b48da862-312f-4ae1-ba72-346d5c4c2e96
Mitochondrial chromosomal abnormality leads to
Leber's hereditary optic neuropathy
Angelman syndrome
Prader villi syndrome
Myotonic dystrophy
0a
single
Ref Robbins 8/e p171;9/e p172 Example of mitochondrial inheritance is leber's hereditary optic neuropathy.leigh's disease ,MELAS - Mitochondrial encephalopathy Lactic acid Stroke like syndrome Neuropathy , ataxia, retinitis, Kearns Sayre syndromes, chronic progressive external opthalmoplegia,Pearson syndrome M
Anatomy
General anatomy
0a3d446a-b19d-464f-b943-07d247aa5046
Gestational sac is seen by TVS at-
5 weeks
6 weeks
7 weeks
8 weeks
0a
single
Ans. is 'a' i.e., 5 weeks [Ref: Dutta's Obs 7th/ep. 68}TVS showso Gestational sac & yolk sac - 5th weeko Fetal pole & cardiac activity - 6th weeko Embryonic movements - 7th weeko Fetal gestational age is best determined by CRL between 7th to 12th weeks (variation +/- 5 days)o Doppler effect of ultrasound can pick up he...
Gynaecology & Obstetrics
Diagnosis of Pregnancy
24529115-b874-4602-bac8-c556ae3de80c
Mechanism of action of transexaminic acid is?
Decrease vascular permeability
Smooth muscle contraction
Activates Plasmin formation
Prevents fibrinolysis
3d
single
Ans. is 'd' i.e., Prevents fibrinolysis o Tranexamic acid binds to the lysine binding sites on plasminogen and prevents its combination with fibrin and thus prevents fibrinolysis.
Pharmacology
null
74e740a7-f4e9-4b75-a190-3dc560b2f498
Rotator interval is between:
Supraspinatus and teres minor
Teres major and teres minor
Supraspinatus and subscapularis
Subscapularis and infraspinatus
2c
single
(c) Supraspinatus and subscapularis- Rotator interval is a triangular portion of shoulder capsule which lies between supraspinatus and subscapularis tendon and coracohumeral ligament passes through it.
Orthopaedics
Injuries Around Shoulder
23a04e1e-6ac1-4851-b0e0-2bc31c2f5840
Which of the following drug is used as a Transcranial patch for Parkinson's disease
Levodopa
Rotigotine
Selegiline
Carbidopa
1b
single
Rotigotine is a non-ergot dopamine agonist indicated for the treatment of Parkinson's disease (PD) and restless legs syndrome (RLS). It is formulated as a once-daily transdermal patch which provides a slow and constant supply of the drug over the course of 24 hours. However, it was withdrawn in 2008 because of crystal ...
Pharmacology
null
0d0d6c5f-a781-487b-801f-2ab4357e74cc
The treatment of Acute Manic Episodes is
ECT
ECT
Diazepam
Sodium valproate
1b
single
Lithium
Psychiatry
null
574099a3-70bd-4d39-b57c-4d761a8e9555
In cochlear implants electrodes are most commonly placed at -
Oval window
Round window
Horizontal semicircular canal
Cochlea
1b
single
null
ENT
null
2d58192a-ba7a-41ca-a7de-fbf3b8044d0d
Hypersensitivity vasculitis is most commonly seen in:
Post capillary venules
Aerioles
Veins
Capillaries
0a
single
. Post capillary venules
Pathology
null
29b6eb2c-71dd-4388-bddb-a19f3218a540
Hill Sach&;s lesion is most commonly seen in
Recurrent shoulder dislocation
Posterior shoulder dislocation
Fracture neck of humerus
Anterior shoulder dislocation
0a
single
HILL-SACH&;S lesion is most commonly seen in recurent shoulder dislocation. It is a posterolateral defect in the head of the humerus.This is produced due to the impact of posterolateral pa of the head of the humerus against the sharp anteraior margion of the glenoid rim. ref:textbook of ohopedics ,john ebnezar,4th edit...
Orthopaedics
Shoulder and arm injuries
455bd18a-8840-415f-b6ba-cdf2dc55df5d
Natural killer cell is -
MHC restricted
Antibody dependent
Null cells
B-lymphocytes
2c
single
Ans. is 'c' i.e., Null cells Null cells (Large granular lymphocytes or LGLIo Null cells are called so because they lack features of surface markers of both B and T lymphocytes. The account for 5 to 10% of peripheral blood lymphocytes.o They are also called "large granular lymphocytes (LGL)"as they contain large azuroph...
Microbiology
Immunology
08fbcc61-7de1-4806-9153-048032b3489e
Radionucleide of choice for the assessment of renal function?
MIBG
DTPA
Thallium
Sulphur
1b
multi
Ans: b (DTPA) Ref: Bailey, 24th ed, p. 129999Tc DTPA (diethyl triamino penta acetic acid)Useful to assess the functional status of kidney.DTPA behaves like inulin: completely filtered by the glomeruli, and not absorbed by the tubules. On using a gamma camera the dynamic action of kidney can be assessed.Other substances...
Radiology
Genito Urinary System
2e7b6669-a00d-46ed-b865-4cd2dad058fe
Best drug for chemoprophylaxis in a pregnant woman who is traveling to chloroquine resistant falciparum malaria endemic zone?
Mefloquine
Doxycycline
Ataquinone/Proguanil
Primaquine
0a
multi
Ans. A. Mefloquine. (Ref. H-17th/pg 1292; Table 203-6)Best drug for chemoprophylaxis in a pregnant woman who is traveling to chloroquine resistant falciparum malaria endemic zone is Mefloquine.Regimens for the Rx of MalariaType of Disease or RxRegimen(s)Uncomplicated Malaria Known chloroquine- sensitive strains of Plas...
Medicine
Infection
faa5126d-1049-4f06-bf2a-ac2aae7f959f
Most common nerve injured in ligation of superior thyroid aery:
Recurrent laryngeal nerve
Facial nerve
Mandibular nerve
External laryngeal nerve
3d
single
The external laryngeal nerve lies in relation to superior thyroid aery. The recurrent laryngeal nerve lies close to inferior thyroid aery.
ENT
null
f4e8f8a7-6e0b-497c-928e-aa93477d1b11
Antiphospholipid syndrome ( APS) is associated with all of the following except:
pancytopenia
Recurrent aboions
Venous thrombosis
pulmonary hypeension
0a
multi
Indications for APLA testing 3 or more consecutive first trimester losses Unexplained IUGR Early onset severe preeclampsia Unexplained thrombosis Autoimmune connective tissue diseases like SLE False positive serological test for syphilis (refer pgno:333 sheila 2nd edition)
Gynaecology & Obstetrics
General obstetrics
d7fc3477-6c0e-4054-86e6-5a6532dc949a
Duret hemorrhage seen in -
Brain
Kidney
Heart
Lung
0a
single
Ans. is 'a' i.e., Brain o Duret - Bernard hemorrhage can be seen with severe compression of the midbrain and other brainstem areas during transtentorial herniation.
Medicine
C.N.S.
a4e65b7c-0b67-4c72-801b-f37b57bc365a
Which of the following is/are features of dishpan digit?
Reddened finger
Exceptionally clean thumb
Fibrous rough callus
All of the above
3d
multi
Dishpan digit Finger of the child who indulges in sucking habit. On examination, it will provide valuable information about the habits. They are: Reddened. Exceptionally clean thumb / nail / finger. Fibrous rough callus.
Dental
null
60137255-30ef-4f50-ae6c-8adbef9ddf67
Age limit for HDI?
25 to 85 yrs
25 to 50 yrs
15 to 45 yrs
50 to 75 yrs
0a
single
According to previous editions of Park (21st/e) the minimum and maximum established values for life expectancy atbirth was 25 years and 85 years, respectively.   However, Now the minimum established value is 20 years and maximum value is the highest observed value during time series, i.e. the country which has the high...
Unknown
null
bcceb61d-71c9-4fe4-98bc-83f4ef1bad78
35-year-old woman presents to OPD with complains of headache after hitting her head accidentally with the wall while doing household chores . An MRI was ordered which confirmed presence of blood clot in the great cerebral vein of Galen. Obstructed vein is a direct tributary of which of the following venous structures?
Emissary veins
Pterygoid venous plexus
Diploic veins
Dural venous sinuses
3d
multi
Veins of the brain are direct tributaries of dural venous sinuses. Emissary veins connect dural venous sinuses with the veins of scalp; Pterygoid venous plexus communicates with cavernous sinus through an emissary vein; Diploic veins lie in channels in the diploe of skull and communicate with dural sinuses, veins of sc...
Anatomy
Brainstem lesions and blood supply of CNS
21e8bc04-fb23-45b1-b232-38e3a05943fd
Cystocoele is prolapse of
Upper 2/3rd of anterior vaginal wall
Lower 2/3rd of anterior vaginal wall
Upper 1/3 of anterior vaginal wall
Lower 1/3 of anterior vaginal wall
0a
multi
Cystocoele is prolapse of the anterior 2/3rd vaginal wall while prolapse of lower 1/3rd of the anterior vaginal wall is called as urethrocele. The anterior wall prolapse or cystocele is the most common form of female pelvic organ prolapse Rectocele is prolapse of lower 2/3rd of the posterior vaginal wall Enterocoele is...
Microbiology
All India exam
b2b5499b-f29d-4854-ba85-2c56496f021a
All of the following drugs cause discolouration of urine EXCEPT :
Nitrofurantoin
Digoxin
Azo dyes
Rifampicin
1b
multi
null
Pharmacology
null
71436754-35e2-4c6e-bb25-ca3b6ba8b9c4
All are true about bulbar urethral rupture, except:
Perineal hematoma
Floating prostate on per rectal examination
Collection of urine in perineum
Bleeding per urethra
1b
multi
Ans. (b) Floating prostate on per rectal examination* Floating prostate is seen in membranous urethral injury* Perineal hematoma seen in Bulbar urethral injury.* Deep Perineal pouch hematoma is seen in Membranous urethral injury.
Surgery
Urethra & Penis
1d004cf3-7beb-498e-a4b9-635a2882edd3
Which of the following is mechanism of action of dapsone?
Inhibit the cell wall synthesis
Inhibit the sterol of cell wall
Inhibit the protein synthesis
Compete with PABA in folic acid synthesis
3d
multi
Dapsone is analogue of PABA Competively inhibits dihyropteroate synthase - decreases folic acid synthesis. It can cause mild hemolysis, anemia and psychosis. Uses: Leprosy Malaria Prophylaxis of pneumocystitis Dermatitis herpetiformis
Pharmacology
Mycobacterial Diseases (TB, Leprosy and MAC)
1085c041-d2db-41fc-ab3f-5ce4daaf78b1
In a 4-year old boy who has history of pyogenic infections by bacteria with polysaccharide-rich capsules, which of the following investigations should he done?
IgA deficiency
IgG 1 deficiency
IgG2 deficiency
IgA and IgG2 deficiency
3d
single
Ans. d. IgA and IgG2 deficiency Recurrent episodes of pyogenic infections by capsulated organisms are most commonly observed in patients with selective IgA deficiency and decreased IgA or IgG subclass levels (especially IgG2). "Specific Antibody Deficiency (SAD) patients generally present with recurrent upper and/or lo...
Microbiology
null
b8b6cd0f-0730-4f26-a57a-8384d20d8bf4
Hurthle cell tumour is:
Papillary carcinoma thyroid
Follicular carcinoma thyroid
Medullary carcinoma
None of the above
1b
multi
HURTHLE CELL CARCINOMA: Hurthle cell carcinomas account for approximately 3% of all thyroid malignancies. Considered to be a subtype of follicular thyroid cancer.
Surgery
null
c4cd0bcf-69dc-4a56-a44a-46ccf0ad0646
Rhinophyma is associated with-
Hypertrophy of the sebaceous glands
Hypertrophy of sweat glands
Hyperplasia of endothelial cells
Hyperplasia of epithelial cells
0a
single
Rhinophyma is a slow-growing benign tumor due to hypertrophy of sebaceous gland.
ENT
null
8d028eef-4996-42d1-ab3c-b34ac7f53ec7
Amphotericin B toxicity can be reduced by?
Incorporating it in liposomal complex
Combining with fluconazole
Combining with flucytosine
Injecting the drug with dextrose
0a
single
New amphotericin B formulations: In an attempt to improve tolerability of i.v. infusion of AMB, reduce its toxicity and achieve targeted delivery, 3 new lipid formulations of AMB have been produced. (a) Amphotericin B lipid complex (ABLC): Contains 35% AMB incorporated in ribbon like paicles of dimyristoyl phospholipid...
Pharmacology
Chemotherapy
43d1e4bf-9bda-4616-986c-d7a21c8df26c
Which of the following sonographic finding confirms intra uterine pregnancy
An echogenic rim along one side of decidua.
Two concentric echogenic rings surrounding the sac.
A sac positioned eccentrically within endometrium.
All of the above.
3d
multi
Normal gestational sac implants eccentrically in the endometrium. Anechoic center surrounded by single echogenic rim = intra-decidual sign. Two concentric rings echogenic surrounding sac = Double decidual sign.
Gynaecology & Obstetrics
null
0d195b51-2758-4be1-8e4e-ff5e73dcbfab
Founder members of vision 2020 are A/E
WHO
UNICEF
ORBIS
International Agency for prevention of blindness
1b
single
B i.e. UNICEF
Ophthalmology
null
bb3a09e3-baae-4a02-bd18-aed70635a855
Which of the following is the auto antibody associated with Rheumatoid arthritis -
Anti DLE
Anti CCP
Antids DNA
Antihistone
1b
single
Anti CCP
Unknown
null
e3dee44b-eadc-4bc7-8800-27d4ab477dfb
In preterm labour which drug has Neuro-protective role?
MgSO4
Nifedipine
Ritoridine
Isoxsuprine
0a
single
Ans. (a) MgSO4 Ref: Williams Obstetrics 25th Ed; Page No-730* To prevent convulsions; Administer IV MgSO4 and Continue IV MgSO4 for 24 hours after delivery.* Always avoid Nifedipine and b-blockers, because they cause severe maternal complication.Antihypertensive Drug Therapy Issues* Discontinue medications: This may be...
Gynaecology & Obstetrics
Pharmacotherapeutic in Obstetrics
5fbf43d1-5be5-4fb3-a7f7-460b8a6ae23c
Dosage of Vitamin–A for children between 1–3 years –
1250 IU
1333 IU
1667 IU
2333 IU
1b
single
null
Pediatrics
null
c8745cac-94bb-4d0c-90aa-756df9973462
Accommodation is brought about by:
Dilation of iris
Dilation of pupil
Lens zonules made tense
Ciliary body contraction
3d
single
Ans: d (Ciliary body contraction) Ref:Ganong, 22th ed, p. 154Accommodation is brought about by ciliary muscle contractionAccommodationThe process by which the curvature of the lens is increased is called accommodation.Mechanism: At rest the lens is under tension by lens ligaments & lens is pulled into a flattened state...
Ophthalmology
Elementary Optics
0fe69853-983a-4e6b-931d-d552f7777928
A patient with suspected subarachnoid haemorrhage presents with blood isolated in the fouh ventricle on a CT scan. Aneurysmal rupture is likely to have resulted from
Posterior Inferior Cerebellar Aery Aneurysm
Anterior Communicating Aery Aneurysm
Posterior Communicating Aery Aneurysm
Basilar Aery Tip Aneurysm
2c
single
*Saccular aneurysm at size of >7mm and at top of basilar aery and at origin of posterior communicating aery are at greater risk of rupture . Ref Harrison20th edition pg 2445
Medicine
C.N.S
6242ae15-336b-47ca-b879-60c9f30402a2
The term 'disease control' employs all of the following except-
Reducing the complications
Reducing the risk of fuher transmission
Reducing the incidence of disease
Reducing the prevalence of the disease
3d
multi
Ans. is 'd' i.e., Reducing the prevalence of the disease o The term disease control describes, reducing the i) The incidence of disease ii) The duration of disease and consequently the risk of transmission iii) The effects of infection, including its complications iv) Financial burden to the community
Social & Preventive Medicine
null
cce222b4-8997-449a-b425-aa2f31e32eb3
In haemoptysis blood usually comes from
Bronchial veins
Pulmonary veins
Bronchial arteries
Pulmonary arteries
2c
multi
null
Medicine
null
eea5b2b7-6b90-4ee5-9f4b-35c6ea77ec6b
Internationally quarantinable disease are -
Plague
Cholera
Yellow fever
All of the above
3d
multi
Ans. is 'd' i.e., All of the above Quarantinable diseases o Diphtheria o Yellow fever o Infectious TB o SARS o Plague o Small pox o Viral hemorrhagic fever Also Know : Quarantine was first applied for plague. Quarantine period for yellow fever is 6 days. Quarantine has been 'replaced by active surveillance'.
Social & Preventive Medicine
null
2e32ec5e-de83-43a2-8083-33c825936ad9
Projections from substantia nigra pars compacta to striatum releases
GABA
Dopamine
Glutamate
Aspartate
1b
single
null
Physiology
null
e88c22c4-23f1-44e2-9f26-a430eaaf3f4e
Sublingual nitroglycerin for treatment of acutechest pain can cause ?
Hypeension
Headache
Bradycardia
Sexual dysfunction
1b
single
Ans. is 'b' i.e., Headache Due to vasodilatation there may be tachycardia, palpitation, flushing, headache, dizziness and fainting may occur. Adverse effects Due to vasodilatation tachycardia, palpitation, flushing, headache, dizziness and fainting may occur. Rashes are common paicularly with pentaerythritol tetranitra...
Pharmacology
null
5bbf4eaa-c62a-4031-ba1a-74c8ce49c6fb
Denominator in dependency ratio ?
Age group < 15 years
Age group 15-65 years
Age group > 65 years
< 15 years and > 65 yeas
1b
single
Ans. is 'b' i.e., Age group 15-65 years Dependency ratio The propoion of persons above 65 years of age and children below 15 years of age are considered to be dependent on the economically productive age group (15-64 years). The ratio of combined age group 0-14 years plus 65 years and above to the 15-65 years age group...
Social & Preventive Medicine
null
b4d58c84-55e0-437a-ad51-d5de19dc2fc6
Metal ceramic restorations fail usually due to fracture of the cervical material. This can be avoided if:
Occlusal forces are minimal
Casting is so designed as to reduce stress on ceramic material
Metal is not more than 0.5 mm thick
Ceramic is at least 1.5 mm thick
1b
multi
null
Dental
null
f1f9342d-8187-48a0-8d52-5e6ab7fa87f2
Skin lesion in meningococcal meningitidis is due to-
Exotoxin
Endotoxin
Allergic reaction
Direct vascular Damage
1b
multi
null
Microbiology
null
3c64e4ad-8d9c-4fbc-9065-c5d1bed748ed
Hand and foot syndrome is an adverse effect of:
5-Fluorouracil
Bleomycin
Etoposide
Actinomycin D
0a
single
Capecitabine and 5-FU can cause hand and foot syndrome. Diarrhea is the most common adverse effect of 5-FU. 5-FU can also cause bone marrow suppression. Drugs commonly implicated are: Capecitabine 5-Fluorouracil Cytarabine Pemetrexed Doxorubicin
Pharmacology
Cytotoxic Anticancer Drugs
5bd7c211-d519-4173-a982-1b501e1943a6
Which of the following skin conditions is treated with PUVA therapy?
Psoriasis
Tinea versicolor
Lichen planus
Porphyria cutanea tarda
0a
single
PUVA is used to treat extensive psoriasis and psoriasis that has not responded to other therapies. PUVA stands for psoralens plus UVA. Psoralens are used orally followed by exposure of lesions to measured amount of a type of ultraviolet light-UVA. Sho term side effects of PUVA therapy include tanning, pruritus, nausea,...
Skin
null
ea3c1658-c844-4fb8-80ac-62973f93f2ed
Products of complete hydrolysis of cardiolipin are:
3 glycerol, 4 fatty acids , 2 phosphates
3 glycerol, 4 fatty acids , 1 phosphates
3 glycerol, 3 fatty acids , 2 phosphates
5 glycerol, 4 fatty acids , 2 phosphates
0a
single
3 glycerol, 4 fatty acids , 2 phosphates Cardiolipin is a complex phospholipid, which can be antigenic. The structure is glycerol attached to two phosphatidic acids. Each phosphatidic acid contains one glycerol, 2 FA and one phosphate. So in total 3 glycerol, 4 fatty acids, 2 phosphates are present in cardiolipin.
Biochemistry
Chemistry of Lipids
101ffce9-309d-44b3-9728-cc577aa81302
All of the following are used for monitoring air pollution except
SO2
Soiling index
Coefficient of haze
E. coli
3d
multi
Indicator for air pollution Remarks Sulphur dioxide Best Smoke and soiling index Air filtered through white paper and stained is measured under photoelectric meter Grit and dust measurement Deposit gauzes collect grit dust and others solid Coefficient of haze Amount of smoke and other aerosol in the air Air pollution i...
Social & Preventive Medicine
Environment
1201e6c5-5070-45c8-b141-3c3f0c2754d1
A newborn with respiratory distress was noted to have marked nasal flaring, audible grunting, minimal intercostal chest retarction. The respiratory rate was 30/min. The Silverman score of this child would be? NOT RELATED- MEDICINE
1
2
3
6
3d
single
.
Pharmacology
All India exam
f7a5befc-c9d7-47bf-a625-52b623c87c25
The symptoms of Hyperparathyroidism include ?
Constipation & muscle weakness
Anorexia & weight loss
Polydipsia & polyuria
All of the above
3d
multi
Ans. is 'd' i.e., All of the above
Surgery
null
1166931d-79a9-4d69-96b7-83c4aa9c0208
Main pancreatic duct is derived from ?
Paly from the dorsal pancreatic bud and paly from the ventral pancreatic bud
Dorsal pancreatic bud only
Ventral pancreatic bud only
None of the above
0a
multi
The pancreas develops from the two endodermal buds, dorsal and ventral, that arise from the pa of the gut that later forms the second pa of the duodenum. The ventral bud forms the lower pa of the head, and the uncinate process of the pancreas, while the upper pa of the head, the body and the tail are formed from the do...
Anatomy
null
e82ebf61-292c-4d7f-a01e-8e39008842a7
Ahritis mutilans is seen in:
OA
Rheumatoid ahritis
Reiters syndrome
Psoriatic Ahropathy
3d
single
Psoriatic Ahropathy
Surgery
null
65be5346-6230-4900-be9d-1a598c785997
Which of the following is TRUE about cholera toxin?
Increases the levels of intracellular cyclic GMP
Acts through the receptor the opiates
Causes continued activation of adenylate cyclase
Inhibits the enzyme phosphodiesterase
2c
multi
V cholerae produce a heat-labile enterotoxin. Ganglioside GM1 serves as the mucosal receptor for subunit B, which promotes entry of subunit A into the cell. Cholera toxin catalyzes the ADP ribosylation of the G protein, rendering it unable to dissociate from the active adenylate cyclase complex. This causes persistent ...
Microbiology
null
b3c251fc-d600-49f0-b005-db8fc46c14cc
Glucose transporters present in the Beta cells of the Islets of Langerhans is:
GLUT1
GLUT2
GLUT3
GLUT4
1b
single
Ans. B. GLUT2GLUTTissue LocationFunctionGLUT 1Brain, Placenta, Kidney, RBCBasal Glucose UptakeGLUT 2Liver, Pancreas, IntestinePancreas-Insulin SecretionGLUT 3Brain (Neurons), PlacentaBasal Glucose UptakeGLUT 4Skeletal Muscle, Adipose Tissue, Cardiac MuscleInsulin stimulated uptake after mealsGLUT 5Small Intestine, Test...
Biochemistry
Carbohydrates
4921c86c-9682-4e1a-8d35-3edb40c45a57
Muscular timidity caused by opioids is due to the agonist effect on which receptor
Mu
Kappa
Delta
Sigma
0a
single
Refer Miller 7/ep781 Truncal rigidity caused by highly lipid soluble opioids like Fentanyl is supraspinal in origin. It is mainly caused by stimulation of mu receptors whereas kappa and delta receptors tend to reduce the rigidity
Pharmacology
Anesthesia
9e14a61e-9991-453a-a7fb-5b0d7251cea0
Maximum radiopaque shadow in ovary is seen in
Teratoma
Dysgerminoma
Mucinous cyst adenoma
Granulose cell tumour
0a
single
Teratoma is most radio-opaque because of its calcifications (Ref: Radiology Review Manual by Wolfgang Dahne 6thEtd, 1010)
Radiology
All India exam
397a34a4-f6ea-4958-bf79-933cddc691c7
Indication for induction of labour is :
Placenta pre
PIH at term
Hea disease at term
Breech
1b
single
PIH at term
Gynaecology & Obstetrics
null
266c3949-61fc-4dfd-98d4-dec06bc18bcd
Antibiotic of choice for lymphedema is ?
Penicillin
Amikacin
Metronidazole
Ceftazidime
0a
single
<p> Lymphoedema Accumulation of fluid in extracellular and extravascular fluid compament , commonly in subcutaneous tissue. Classification: 1. Primary - without any identifiable disease. 2. Secondary- acquired due to definitive cause. Primary lymphoedema:- Affects commonly females. Common in lower limb and left side. I...
Surgery
Vascular surgery
fbe76a8e-8638-4bce-824d-b9ad3cf05cdc
What is the content of ethinyl estradiol in very low
30µg
25µg
20µg
15µg
2c
single
null
Social & Preventive Medicine
null
99d67a98-3952-49bd-9bee-2e551e245e25
The first step in fatty acid synthesis involves:
Acetyl-CoA carboxylase
Hydroxyl-CoA dehydrogenase
Acetyl dehydrogenase
Pyruvate kinase
0a
multi
Ans. A. Acetyl-CoA carboxylase(Ref Harper 31/e page 217)Fatty Acid SynthesisBy two enzyme system1. Acetyl-CoA carboxylase2. Fatty acid synthase complexAcetyl-CoA CarboxylaseConverts acetyl-CoA (2C) to malonyl-CoA in the presence of ATP.Acetyl-CoA carboxylase has a requirement for the B vitamin biotin.It is a multienzym...
Biochemistry
Lipids
7fd604f4-2708-4088-94ff-a76e3fd8d966
Maxillary sinus opens into which meatus?
Inferior
Superior
Middle
All
2c
multi
Ans. c (Middle meatus). (Ref. Bhargaw, 5th ed.151)THE LATERAL NASAL WALL# It consists anteriorly of the nasal bone, frontal process of maxilla & the lacrimal bone.# Posterior to lacrimal bone, the lateral wall of nasal cavity is formed by ethmoid labyrinth, maxillary & inferior concha.# Perpendicular plate of palatine ...
ENT
Nose and PNS
3338b008-1f10-4104-9408-00daabc3f964
Which of the following is not true about Xenon anesthesia?
Non explosive
Minimal cardiovascular side effects
Slow induction and slow recovery
Low blood gas solubility
2c
multi
Ans. c. Slow induction and slow recovery Xenon anaesthesia is inert, non-explosive, environment friendly having low blood solubility with minimal cardiovascular side effects. Lower blood gas coefficient of Xenon results in rapid induction and recovery.Xenon Anesthesia* Xenon was isolated by William Ramsay (Nobel prize ...
Anaesthesia
Miscellaneous General Anesthesia
c7dc25f7-ffd5-4f9b-bd51-eeef47bcc046
A male with azoospermia. On examination size of testis normal FSH normal testosterone normal. Most probable cause is:
MAL descended testis
Klinefelter's syndrome
Kallmann's syndrome
VAS obstruction
3d
multi
Ans. is d, i.e. VAS obstructionSince all FSH, LH and Testosterone are normal therefore, it has to be an obstructive cause. Amongst the option, VAS obstruction is the only obstructive cause and hence our answer.
Gynaecology & Obstetrics
Endometriosis and Infertility
e4012dca-8632-44f1-b40d-a28dd7cf8fe7
a 40 yr old man underwent renal transplantation two months after transplantation he developed fever and features suggestive of bilateral diffuse interstitial pnuemonitis. what is causative agent ?
HSV
CMV
EBV
VZV
1b
single
PERSONS WITH HIGH RISK OF CMV INFECTION : organ transplantation with malignant tumors who are recieving chemotherapy with hiv/aids viral excreation is icreased and prolonged diffuse interstitial pneumonia is common complication ref : ananthanaryana 9th ed
Microbiology
All India exam
dec6e9e4-b194-431f-9fa1-659e4d8dc8c3
Infants acquire adult hemoglobin level at:
Birth
End of 1st year
Puberty
4 years
1b
single
null
Physiology
null
897920f2-ed35-4fbb-a5fc-bda825e39195
A child presented to the emergency depament with seizures. On examination oval hypopigmented macules were noted on the trunk, along with sub-normal IQ. What is the probable diagnosis?
Neurofibromatosis
Sturge Weber
Tuberous sclerosis
Incontinentia Pigmenti
2c
single
Essentials of Diagnosis & Typical Features of Tuberous sclerosis: Facial angiofibromas or subungual fibromas. Often hypomelanotic macules, gingival fibromas. Retinal hamaomas. Coical tubers or subependymal glial nodules, often calcified. Renal angiomyolipomas. Seizures are the most common presenting symptom. Up to 20% ...
Pediatrics
null