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135
5869cee3-fe75-4e5e-8f77-052a6a724546
Which of the following deficiency in alcoholics inhibit pyruvate dehydrogenase?
Thiamin
Niacin
Riboflavin
Ascorbic acid
0a
single
Arsenite and mercuric ions react with the - SH groups of lipoic acid and inhibit pyruvate dehydrogenase, as does a dietary deficiency of thiamin, allowing pyruvate to accumulate. Many alcoholics are thiamin-deficient (both because of a poor diet and also because alcohol inhibits thiamin absorption), and may develop pot...
Biochemistry
null
ef08b696-e95c-48d5-92d7-151cd5504a4b
Compared to the other antidepressant drugs mirtazapine has the distinct ability to act as an antagonist of :
Beta receptors
D2 receptors
Alpha 2 receptors
5-HT receptors
2c
single
null
Pharmacology
null
c1141cca-a33f-4001-830f-d3c0a7bea1eb
Tetracycline injection causes palsy of which nerve?
Ulnar
Median
Radial
Superficial Radial Nerve injury
2c
single
Ans. is 'c' i.e., Radial
Pharmacology
null
dff710d7-47a5-4f56-a5eb-c85d918d6812
Which of the following is key area of nasal septum?
Anterosuperior pa of nasal septum
Anteroinferior pa of nasal septum
Posterosuperior pa of nasal septum
Posteroinferior pa of nasal septum
1b
single
.
Pathology
All India exam
193bb7c1-ba4e-4928-bcbf-9be0f7878eba
An 83-year-old man with Parkinson's disease presents with low-grade fever and cough for several weeks. Lately, he has been experiencing more rigidity and difficulty with his walking. He is on a levodopa/carbidopa combination for treatment for the past 5 years. On examination, his gait is shuffling and slow. He has a tr...
oropharyngeal flora
tuberculosis
Staphylococcus aureus
Pseudomonas aeruginosa
0a
single
Most lung abscesses and all anaerobic abscesses involve the normal flora of the oropharynx. Septic embolic usually contain S. aureus. Factors that predispose to Gram-negative colonization of the oropharynx include hospitalization, debility, severe underlying diseases, alcoholism, diabetes, and advanced age. Impaired co...
Medicine
Respiratory
b2dbe8ac-5af8-4362-9f0f-a9cf94bfedba
A patient with microcytic hypochromic anemia. Hb-9 g%, serum iron-20 microg/dl, ferritin level-800 ng/ml, transferrin percentage saturation is 64%. What is possible diagnosis?
Atransferrinemia
Iron deficiency anemia
DMT 1 mutation
Anemia of chronic disorder
0a
single
Ans. (a) Atransferrinemia(Ref: Wintrobe's 12th/pg814)This patient with microcytic hypochromic anemia, has high ferritin level (800ng/ml) & increased transferrin percentage saturation (64%). The most possible diagnosis is Atransferrinemia.AtransferrinemiaIt is a rare congenital autosomal recessive condition with low tra...
Pathology
Misc. (R.B.C)
938dae46-070d-4e45-ba68-e4364cb73b7d
What does Gettlers test detects -
Diatoms in drowning
Chloride content of blood in drowning
Weight in drowning
None
1b
multi
Reff: The synopsis of forensic medicine & Toxicology 28th edition pg: 194 In 1921, Gettler published a test for drowning from right and left hea chambers, a difference of 25mg/100ml between the chlorides concentrations of the two sides of the hea indicated that the death was due to drowning. In freshwater drowning the ...
Forensic Medicine
Asphyxia
c3cbc758-268b-40a8-8e04-06ee4bad9483
Functional unit for implementation of National Mental Health Programme is at which level?
District
Subcentre
PHC
State
0a
single
The Government of India has launched theNational Mental Health Programme(NMHP) in 1982, keeping in view the heavy burden of mental illness in the community, and the absolute inadequacy of mental health care infrastructure in the country to deal with it. Principal unit of Health administration in India is District under...
Social & Preventive Medicine
Other NHPs
477aeeb4-d0b5-499f-b2b2-1cfa88860fcc
To prevent keratoconus what is used –
Antibiotics
Cycloplegics
Glasses
None
3d
multi
There are no preventive measures for keratoconus. Some specialists believe that patient with keratoconus should have their eye allergies aggressively treated and should be instructed not to rub their eyes
Ophthalmology
null
d3e749dd-9d30-48f9-b050-46138d1376a7
Following ultrasound is showing-
Normal pregnancy
Ectopic pregnancy
H. mole
Ovarian cyst
1b
single
Ans. is 'b' i.e., Ectopic pregnancy* Empty endometrial cavity with an extrauterine single gestational sac with yolk sac in left adenexa. Both ovaries are normal. It is indicative of left adnexal, unruptured ectopic pregnancy.
Gynaecology & Obstetrics
Miscellaneous (Gynae)
4dd139ec-8cdb-46c2-97d6-4a37f57701ad
What is the structure seen in the given X-ray below?
Stent
Surgical clips
Foley catheter
Intravesical wire
0a
single
Plain abdominal X ray showing a stent in the right and left ureter. Ureteric stents,also known as double J stents or retrograde ureteric stents, is a urological catheter that has two "J-shaped" (curled) ends, where one is anchored in the renal pelvis and the other inside the bladder. Stents are used for the free passag...
Radiology
All India exam
5457999e-c4e3-4d59-ba60-94c81097022d
Limiting amino acid in wheat are:
Lysine, arginine
Threonine, methionine
Lysine, threonine
Lysine, methionine
2c
single
Limiting amino acid in various food stuffs Wheat-lysine (the most deficient) and threonine (second limiting amino acid) Rice-lysine Legumes-tryptophan or methionine (or cysteine) Maize-lysine and tryptophan Egg-none; the reference for absorbable protein
Biochemistry
null
07846002-ed62-4fc4-811e-de10d5e53c34
All of the following are true regarding whooping cough except:
Spread by droplet infection
90% of cases occur in children under 5 years of age
The whoop stage is more infectious than catarrhal stage
Blood count shows lymphocytosis
2c
multi
Ans: cRef: Harrison, 16th ed, p. 875, 876
Medicine
Infection
70a64eaf-fc06-4396-ae85-abb7829b13c9
Maximum density of goblet cells is seen in:
Superior conjunctiva
Inferior conjunctiva
Nasal conjunctiva
Temporal conjunctiva
2c
single
C i.e. Nasal conjunctiva Goblet cells are the chief source of tear mucus Q. These occur throughout the conjunctiva, especially the plica semilunaris.
Ophthalmology
null
3b78cc65-1321-4a8b-8e97-3852be0044b7
The histiocytosis X is a spectrum of disorders, which include the following condition
Eosinophilic granuloma
Hand Schuller - Christian disease
Letterer - Siwe disease
All of the above
3d
multi
null
Pathology
null
3223ba5c-8db2-40cc-bd7b-c0cc589615a1
In frey's syndrome, neurotransmitter is:
Acetylcholine.
Epinephrine.
Norepinephrine.
Serotonin.
0a
single
null
Pathology
null
30d24063-886a-45e4-9e82-46aff1052b0c
All of the following are seen in Systemic Juvenile Ahritis except
Rheumatoid Factor +ve
Hepatosplenomegaly
High fever with rash
Elevated E.S.R
0a
multi
Rheumatoid factor is negative in systemic onset JIA Ref Ghai pediatrics eighth edition pg no 626
Pediatrics
Musculoskeletal disorders
5420c6b5-7fad-4770-99b0-2fba04a7f72b
A village with 10000 population 250 suffered from malaria out of which 50 dead, another 100 suffered from dengue out of which 30 died in 2013 case fatality rate of dengue is -
40 '
80
30
70
2c
single
Ans. is 'c' i.e., 30 CFR =Total no. of deaths due to a diseaseTotal no. of cases of the same diseasex 100 CFR due to dengue=No. of death due to dengueTotal cases of denguex 100 =30100x 100 = 30
Social & Preventive Medicine
Measurement of Mortality and Morbidity
4468ff64-b65c-4f6b-8b06-b6e84e1cdf51
All are true about mammary gland, except ?
Is a modified sweat gland
Extends from 2nd to 6th rib veically
Supplied by internal mammary aery
Nipple is supplied by 6th intercostal nerve
0a
multi
Ans. is 'd' i.e., Nipple is supplied by 6th intercostal nerve Mammary gland Breast (mammary gland) is a modified sweat gland present in the superficial fascia of pectoral region. Veically it extend from 2" to 6' ribs at midclavicular line and horizonal extent is from sternal margin to midaxillary line at the level of 4...
Anatomy
null
f58d5dd3-6978-422d-bc88-8df4fc1b7404
In diffuse calcification of pancreas calcium lies in?
Acinar tissues
Interstitium
Pancreatic ducts
Any where
3d
single
Ans. is 'd' i.e., Anywhere
Pathology
null
d1890112-ae22-4742-8aaa-3e9a2e593d2d
Most common lung cancers in non smokers is
Squamous cell carcinoma
Bronchoalveolar carcinoma
Small cell carcinoma
Adenocarcinoma
3d
multi
Adenocarcinoma is the most common lung cancers in non smokers.
Medicine
null
bca7c6ea-da3c-4ae0-be48-4e4d117b7c97
BCR-ABL fusion gene is detected by?
Flow cytometry
FISH
Karyotyping
RT-PCR
1b
single
Ans. (b) FISH(Ref: Robbins 9th/pg 616-618)Flow cytometry: is used for immunophenotyping in Leukemias & LymphomasFISH- used for detecting submicroscopic chromosomal aberrations of BCR-ABL fusionKaryotyping: Used for detecting chromosomal defects of at least 5 mb size (low sensitivity)RT-PCR: used for quantitative DNA es...
Pathology
Misc. (W.B.C)
03e894aa-0c5e-44dd-b240-97bfbf3cabba
In a patient with head injury, unexplained hypotension warrants evaluation of:
Upper cervical spine
Lower cervical spine
Thoracic spine
Lumbar spine
2c
single
High thoracic or cervical cord transection causes hypotension and bradycardia due to functional sympathectomy (sometimes with Horner syndrome). Ref: Harrison's Principles of Internal Medicine, 15th Edition, Page 2441; Surgery: Basic Science and Clinical Evidence By Jeffrey A. Noon, Philip S. Barie, Randall Bollinger, 2...
Surgery
null
108cd666-f90d-45a2-939c-830582f4076e
NOT a mutation in Down's syndrome
Mosaicism
Robersonian translocation
Maternal non disjunction
VNTR's
3d
single
(D) VNTR's# A Variable Number Tandem Repeat (or VNTR) is a location in a genome where a short nucleotide sequence is organized as a tandem repeat is associated with major psychiatric disorders.> Trisomy 21 also known by the karyotype 47, XX+21 for females and 47,XY,+21 for males.> The extra chromosome 21 material may a...
Pathology
Misc.
d8ed37c8-5125-4883-bcf5-ac9e2395e106
Sironemelia is caused due to effect in ?
Endoderm
Mesoderm
Ectoderm
None of the above
1b
multi
Gastrulation itself may be disrupted by genetic abnormalities and toxic insults. In caudal dysgenesis (sirenomelia), insufficient mesoderm is formed in the caudalmost region of the embryo. Because this mesoderm contributes to formation of the lower limbs, urogenital system (intermediate mesoderm), and lumbosacral veebr...
Anatomy
null
a2952605-b6b4-4717-b51f-800ce497b5d5
Ulcerative colitis starts in :
Descending colon
Transverse colon
Caecum
Rectum
3d
single
null
Surgery
null
c836f213-8fad-4947-bbc1-4efd2e3cee0e
A gastric ulcer is said to be refractory when it fails to heal after therapy for:
6 weeks
8 weeks
12 weeks
14 weeks
2c
single
A gastric ulcer that fails to heal after 12 weeks and a duodenal ulcer does not heal at 8 weeks of therapy should be considered refractory. Cause of refractory ulcers: Malignancy Zollinger Ellison syndrome Cigarette smoking Ischemia Crohn's disease Lymphoma Eosinophilic gastroenteritis Infections (TB,CMV) Ref: Harrison...
Medicine
null
8845d5fb-1445-492d-877d-68f59ec7c0ab
Induction at term is not done in
Preeclampsia
Diabetes
Hea disease
Renal disease
0a
single
Preeclampsia is associated with significant maternal and fetal morbidity and moality. No pregnancy complicated by preeclampsia should be allowed to cross 38 weeks and earlier terminations will often have to be considered depending on maternal and fetal status. Refer page no 559 of Textbook of obstetrics, Sheila Balakri...
Gynaecology & Obstetrics
General obstetrics
196d5107-9b2c-43f4-a7ba-f2dba3ae8041
The following are true regarding Lyme's Disease, except -
It is transmitted by ixotid tick.
Erythema chronicum migraines may be a clinical feature
Borrelia recurrentis is the aetiological agent
Rodents act as natural hosts
2c
multi
Borrelia burgdorferi is the causative agent of Lyme’s disease Lyme’s disease is transmitted by ixodid tick Erythema migrans (annular skin lesions) occurs in 1st stage Rodents act as natural hosts.
Microbiology
null
3d5cb615-92b7-4ba5-a2fd-9ae68d57012a
A child presents with a lesion on the face as depicted on the PLATE. The biopsy from the lesion is also shown. What is the most probable diagnosis?
R Alba
Lepromatous Leprosy
Indeterminate leprosy
Pityriasis Rosea
2c
single
ANSWER: (C) Indeterminate LeprosyREF: IAL textbook of leprosy P:157CAUSES OF HYPOPIGMENTED WHITE LESION ON FAE OF CHILD* Pityriasis Alba* Vitiligo* Indeterminate Hansen* Albinism* Halo nevus* Post-kala-azar dermal leishmaniasis* Seborrheic dermatitis* Pityriasis Versicolor See PLATE - KEY INTERMEDIATE LEPROSY(A) Morpho...
Unknown
null
de884a8d-83a2-47e5-8f7a-423492d5cda4
The following tests are used to check the efiiciency of pasteurization of mild except -
Phosphatase test
Standard plate count
Coliform count
Methylene blue reduction test
3d
multi
Methylene blue reduction test is an indirect method for detection of microorganism in milk. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 606
Social & Preventive Medicine
Nutrition and health
245603af-6394-429f-9428-2c5afb784bd5
All can take split thickness graft except -
Fat
Muscle
Skull bone
Deep fascia
2c
multi
"The skin graft must be applied to a well-vascularized recipient wound bed. It will not adhere to exposed bone, cartilage, or tendon devoid of periosteum, perichendrium or peritenon, respectively, or devoid of its vascularized perimembranous envelope." - Sabiston 17/e p 2185
Surgery
null
1c9ce032-cf70-4271-a044-b50a52d9516e
Not a differential Diagnosis for grey white membrane on Tonsil
Candidiasis
Ludwig's Angina
Vincent's Angina
Malignancy tonsil
1b
single
null
ENT
null
4e6bf53f-f3b2-4d0a-9155-5c45fead1013
True about gastric stump carcinoma
Enterogastric reflex is the cause
Prognosis good after surgery
It is always adenocarcinoma in nature
Diffuse type is only variety
0a
multi
Usually, after Billroth II operation altered acid level, enterogatric bile reflux is the pathogenesis which increases the peptic activity causing mucosal metaplasia and dysplasia resulting in stump carcinoma Reference SRB edition:5 page:845
Surgery
G.I.T
b25e080c-1188-4b84-803e-acae16a17f4c
Lower 1/3'd of anal canal is derived from?
Proctodaeum
Cloaca
Urogenital Sinus
Midgut
0a
single
Ans. is'a'i.e., Proctodaeum(Ref: BDC Sh/eVol. Il p. 415)'The lower third of the anal canal is an ectodermal derivative and is derived from the proctodaeum.'Pa of anal canal above pectinate line develops from dorsal pa of md.odermal cloaca (primitive rectum) and pa of anal canal below pectinate line develops from ectode...
Anatomy
null
dffef730-fa4d-44ec-baaa-ac6a57e3370a
Treatment for achalasia associated with high rate of recurrence :
Pneumatic dilatation
Laproscopic myotomy
Open surgical myotomy
Botulinum toxin
3d
single
Treatment of Achalasia The aim of treatment is to relieve the functional obstruction at the cardio The two main methods to achieve this are Forceful dilatation or Esophageal myotomy (Heller's myotomy) with or without an antireflux procedure 1) Forceful dilatation (pneumatic dilatation) The aim is to weaken or rupture t...
Anatomy
G.I.T
3061bdab-ea7b-4e3b-97b4-ded37abb8a28
Antibiotic treatment of choice for treating cholera in an adult is a single dose of:
Tetracycline
Co-trimoxazole
Doxycycline
Furazolidone
2c
single
Doxycycline - antibiotic of choice for adults only single dose suffices. TMP-SMX - antibiotic of choice for children. Furazolidone - antibiotic of choice for pregnant women. Ref: Park's Textbook Of Preventive And Social Medicine By K. Park, 19th Edition, Page 193; Park's Textbook Of Preventive And Social Medicine By K....
Social & Preventive Medicine
null
7422396e-c847-42cc-af10-6ad261ebfe0a
In treatment of papillary carcinomas thyroid, radioiodine destroys the neoplastic cells predominantly by
X rays
β rays
γ rays
α particles
1b
single
I131 is treated by the body just like the ordinary nonradioactive isotope, so that when swallowed it is concentrated in the thyroid gland. It emits mainly β radiation (90%) which penetrates only 0.5 mm of the tissue and thus allows therapeutic effects on the thyroid without any damage to the surrounding structures, par...
Surgery
null
50fdbc42-2ea4-4934-b036-09b2aa3becbc
An IgG2 molecule is composed of which of the following?
One alpha, one gamma, and two kappa chains
One gamma1 chain and two kappa chains
Two gamma1 chains and one kappa and one lambda chain
Two gamma2 chains and two kappa chains
3d
single
IgG molecules contain two gamma heavy chains of a given subtype and two light chains (either kappa or lambda). The 2 in IgG2 indicates the subclass to which the molecule belongs. IgG2 contains two gamma2 chains (since a given B cell can only form one type of heavy chain). The IgG molecule will contain either two kappa ...
Microbiology
null
4e6f3949-2418-41aa-8797-3618ba03e6e5
Find therapeutic index of drug from the information given below in the graph
128
1024
8
16
3d
single
TI = LD50/ED50 TI = 128 mg/8 mg = 16
Pharmacology
FMGE 2019
f2e89316-8348-4e01-b1aa-927aff5b7da1
Inferior mesenteric vein drains into vein-
Splenic
Hepatic
Portal
Inf. vena cava
0a
single
Splenic
Unknown
null
faa271b0-0ba6-4ad4-a8b7-0647087451b8
Pituitary diabetes insipidus is improved by?
Water restriction
Lithium
Chlorpropamide
Chlohiazide
2c
single
CHLORPROPAMIDE : This Anti-diabetic drug was withdrawn from market as it causes SIADH. So theoretically, it can be used in diabetes insipidus. But the DOC for treatment of Central Diabetes Insipidus: Desmopressin
Medicine
Disorders of pituitary gland
929eb584-78d3-4865-81de-4b530a5f56f9
General anaesthetic most likely to cause bronchodilation is
Thiopentone
Ketamine
Propofol
Fentanyl
1b
single
null
Pharmacology
null
c06bec9b-c2af-4632-b0ff-aa5dc99a5ca0
somatic efferent nerves are all except:
Occulomotor
Trochlear
Trigeminal
Abducent
2c
multi
Somatic efferent nerves, also called as general somatic efferent (GSE) nerves, supply skeletal muscle of somatic origin. Somatic efferent nerves are: • Occulomotor (3) • Trochlear (4) • Abducent (6) • Hypoglossal (12)
Anatomy
null
ef9bc893-c0eb-4c1b-9a21-71a6a843270c
Which of the following is an ionic channel ?
a -1 receptors
b - 1 receptors
Nicotinic cholinergic receptors
Muscarinic cholinergic receptors
2c
single
Ans. is 'c' i.e., Nicotinic cholinergic receptors
Pharmacology
null
8d80d19f-8e39-45b9-a512-d26c49606bf2
Na+ – K+ ATPase
3 Na+ out/ 2K+ in
3Na+ in/ 2K+ out
2Na+ out/ 3K+ in
2Na+ in/3K+ out
0a
single
In Na+-K+ exchange, 3 Na goes out and 2K goes in to the cell.
Physiology
null
ddd43c2d-d035-4720-af60-a9ce27d5bfe2
Glycine is useful in all of the following except -
Purine synthesis
Creatine synthesis
Spermine synthesis
Heme synthesis
2c
multi
Ans. is 'c' i.e., Spermine synthesis Glycineo Glycine is a nonessential amino acid which is synthesized from serine. Glycine is metabolized by following three pathways -It can be converted to serine, a reaction that require tetrahydrofolate {derivative of folic acidQ) and pyridoxal phosphateQ as coenzyme. Further serin...
Biochemistry
Metabolism of Purines and Pyrimidines
1314bdbc-21b0-4966-886b-f60ea4fbee1b
Granulomatosis hepatitis is not caused by:
Blastomycosis
Metastatic carcinoma
Tuberculosis
Cat scratch disease
1b
single
Granulomatous hepatitis is a cause of pyrexia of unknown origin and granulomas are picked up on CT scan or USG abdomen. It is associated with infections like tuberculosis, cat scratch disease, blastomycosis, histoplasmosis.
Medicine
Hepatitis
5466afa8-02a3-480b-8269-f6a34433e11c
Apple jelly nodule in Nasal septum
Syphilis
Leprosy
Lupus vulgaris
Wegener's Granulomatosis
2c
single
null
ENT
null
7627cdba-8054-455d-840c-b3b54b457efb
The inner wall of the tubule is highly calcified and termed as
Peritubular dentin
Intratubular dentin
Both
Mantle dentin
2c
multi
Dentin is made up of dentinal tubules. The dentinal tubules contain the protoplasmic process of the odontoblasts called odontoblastic process. The inner wall of the tubule is highly calcified and is termed as peritubular or intratubular dentin. Between the tubules is the intertubular dentin and it is calcified to a les...
Dental
null
eec3a8ae-117a-4fdc-aaa1-5c764d3bec3c
Duodenal blow out is usually seen at which day of the post operative period?
4th
11th
2nd
7th
0a
multi
Ans: a (4th day)Duodenal blow out usually occurs between 2-7 days of surgery, more specifically on the 4th.It presents as abdominal pain, tachycardia, worsening of the general condition of the patient.It usually occurs after Billroth -II gastrectomyManagement:Total parenteral nutrution is given, catheter is placed imme...
Surgery
Stomach & Duodenum
fa7ac1e6-a7cd-4fb6-ae6d-eb432a54d80a
Super carrier of HBV shows following serum markers ?
HBsAg
HbsAg + HBV DNA
HbsAg + HBeAg + HBV DNA
Anti-HBsAg + HBV DNA
2c
single
Ans. is 'c' i.e., HbsAg + HBeAg + HBV DNA In HBV infection, there are two types of carriers : Super Carriers High titre of HBs Ag, HBe Ag, DNA polymerase and HBV in the circulation Highly infective Simple carriers Low titre of HBsAg with negative HBe Ag, DNA polymerase and HBV Have low infectivity
Microbiology
null
a3a57d7a-c81d-4cda-be2e-7d28ee29688b
NNN media used in?
Leishmania
Histoplasma
Trypanosoma
Entamoeba
0a
single
Diagnosis Novy-Macneal-Nicole Medium Laboratory diagnosis of leishmaniasis can include the following: Isolation, visualization, and culturing of the parasite from infected tissue Serologic detection of antibodies to recombinant K39 antigen Polymerase chain reaction (PCR) assay for sensitive, rapid diagnosis of Leishman...
Microbiology
general microbiology
4798e068-b663-4127-814f-58927566011e
How many pairs of flagella does Giardia lamblia possess -
One
Two
Three
Four
3d
single
Ans. is 'd' i.e., Four Giardia (review)o Giardia is a flagellate protozoao It is the only common protozoa that inhabits the duodenum and jejunum (upper small intestine) of human.o Infective form - cysto Mode of transmission - Ingestion of cysto Giardia exists in two forms
Microbiology
Parasitology
48a76a40-bca9-4936-b7b1-f4efaca201ba
A 27 years old P2L2 has come to OPD for contraceptive advice. She has delivered a male child 3 weeks back and is presently lactating. She has no contraindication of any hormone use. She can be given-
DMPA
Minipill
Levonorgestrol implants
Combined OCPs
1b
single
Progestin-only Contraception methods do not impair milk production and are an excellent choice for lactating women. There are no increased risks of genital tract or breast neoplasia MEC 1 However, after the initial 6 weeks of delivery are over, use of IUCDs is equally good. OCP contain estrogens which significantly red...
Gynaecology & Obstetrics
Puerperium
68e90803-2748-46c5-b982-84483ab34e16
Endometrial repair after menstrual bleeding is under the influence of which hormone ?
FSH
Progesterone
Estrogen
LH
2c
single
Ans. is 'c' i.e., EstrogenAfter mensturation there is proliferative phase, which is under the control of estrogen.Secretory phase is controlled by progesterone
Gynaecology & Obstetrics
null
9351ace8-c88c-4536-895a-2afe55eb7e9d
A 18yr old girl comes to gynaec OPD presenting with 6months A amenorrhea with his low grade fever weight loss pain abdomen generalised weakness On clinical examination pelvic mass felt on left side with features of ascites Diagnosis
TB pelvic with tuboovasion mass
ectopic pregnancy
Granulosa cell tumour
Fibroid with degeneration
0a
single
ref : shaw gynecology
Gynaecology & Obstetrics
All India exam
1147973b-6b69-4447-ad7a-23ac66cfd08d
A 25 yr old female presented with malaise and generalized weakness since 6 months. Her appetite is reduced and she has giddiness and palpitations on and off. There was no organomegaly. Laboratory study showed normochromic to hypochromic anaemia, RDW=60, and MCV=50. What is the diagnosis ?
Thalasemia minor
Iron deficiency anaemia
Chronic malaria
Folate deficiency
1b
single
null
Medicine
null
c3870125-a555-459a-8762-76d5aea29085
Radioactive phosphorus is used in the treatment of –
Polycythemia
Thyroid metastasis
Multiple myeloma
Embrynal cell carcinoma
0a
single
Amongst the given options, Radioactive phosphorus has a well-established role in polycythemia vera. It has also been tried in multiple myeloma, however, its use for this is still debatable.
Radiology
null
47718736-f2ae-4566-818b-7f1e88e2fb41
Vitamin K is a cofactor in
Carboxylation
Hydroxylation
Deaminatiom
Hydrolysis
0a
single
Refer Katzung 10/e p 549 Vitamin K is involved in activition if various clotting factors as well as anticlotting clotting proteins It carries out the final step in activation of these ors I. E, gamma carboxylation of glutamate residues in these factors
Pharmacology
Respiratory system
a42988ae-5dba-4560-89ac-54d4c0174e7f
Pseudomembranous colitis, all are true except -
Toxin A is responsible for clinical manifestation
Toxin B is responsible for clinical manifestation
Blood in stools is a common feature
Summit lesions is early histopathological finding
2c
multi
Ans. is 'c' i.e., Blood in stools is a common feature
Microbiology
null
05cfec95-b551-488c-83ee-f0f4e15c9496
Amyloid deposit stain positively with all of the following except
Congo red
Crystal violet
Methanamine silver
Thioflavin T
2c
multi
Ref Robbins 9/e p262 The Modified Gomori Methenamine-SilverNitrate Stain (GMS Stain) is intended for usein the histologic visualization of fungi, basement membrane and some oppounistic organisms such as Pneumocystis carinii.
Anatomy
General anatomy
9dffa5b1-1c67-41df-90f8-b88df616543d
In an experiment, metabolically active cells are subjected to radiant energy in the form of x-rays. This results in cell injury caused by hydrolysis of water. Which of the following intracellular enzymes helps to protect the cells from this type of injury?
Endonuclease
Glutathione peroxidase
Lactate dehydrogenase
Phospholipase
1b
multi
The body has intracellular mechanisms that prevent damage from free radicals generated by exposure to x-rays. Glutathione peroxidase reduces such injury by catalyzing the breakdown of hydrogen peroxide. Endonucleases damage DNA in nuclear chromatin. Lactate dehydrogenase is present in a variety of cells, and its elevat...
Pathology
Cellular Pathology
39e0c7e3-f45a-4b51-81c8-cb4b3e759498
The definition of Epidemiology as The study of the distribution and determinants of disease frequency in man was given by
John M. Last
Winslow
MacMahon
Frost
2c
single
null
Dental
null
62a6cedf-ba1f-4ca0-a95c-5853454b8383
Which of the following conditions is diagnosed using Cozen's test?
Little leaguer's elbow
Tennis elbow
Golfer's elbow
Frozen shoulder
1b
single
Cozen's test - In this test active extension of wrist against resistance produces pain at the point of common extensor origin. It is considered a positive finding for lateral epicondylitis or Tennis elbow.
Surgery
null
c8f49d61-4fc1-4642-af00-3a8e7868561e
Which of the following is true about cementum
It forms a part of periodontium and is avascular.
Its function is to attach tooth to PDL.
It provides anchorage to the tooth.
All of the above
3d
multi
null
Dental
null
5dd21e15-236d-401e-8d9d-00e0ec553c01
Chronic calcific pancreatitis is associated with all of the following except: September 2005
Hypercalcemia
Diabetes mellitus
Malabsorption of fat
Diabetes associated complications are uncommon
0a
multi
Ars. A: Hypercalcemia Chronic calcifying pancreatitis is invariably related to alcoholism. The earliest finding is precipitation of proteinaceous material in the pancreatic ducts that forms protein plugs that subsequently calcify. The pancreatic ductal epithelium undergoes atrophy, hyperplasia, and metaplasia at the si...
Surgery
null
ae81c5d1-b01b-463f-9a7b-45aa6a217de5
Which of the following artery supplies lower 2/3rd of thyroid lobe, trachea, thymus
Inferior thyroid artery.
Superior thyroid artery.
ECA
All of the above
0a
multi
Superior thyroid artery is the first anterior branch of external carotid artery. It is intimately related to external laryngeal nerve. The superior thyroid artery supplies upper one third of thyroid lobe and the upper half of isthmus. The inferior thyroid artery is a branch of thyro cervical trunk, which arises from su...
Anatomy
null
b193a37a-1740-4567-aaa4-0a93ea428a2f
The child , Draws triangle from a copy at _______.
30 months
36 months
48 months
60 months
3d
single
Emerging patterns of Adaptive milestones from 1-5years of age 15months Makes a tower of 3 cubes Makes a line with a crayon Inses raisin in a bottle 18months Makes a tower of 4 cubes Imitates scribbling Imitates veical stroke Dumps raisin from a bottle 24months Makes a tower of 7 cubes (6 at 21 mo) Scribbles in a circul...
Pediatrics
Growth and development
c4f593ff-e24d-46af-8d60-6a204ef4db74
Which of the following is not associated with multiple myeloma?
Bone pain
Metastatic calcification
Punched out lesion in the skull
Carpopedal spasm
3d
single
MULTIPLE MYELOMA : Bone pain is the most common symptom in myeloma, affecting nearly 70% of patients. Unlike the pain of metastatic carcinoma, which often is worse at night, the pain of myeloma is precipitated by movement. Persistent localized pain in a patient with myeloma usually signifies a pathologic fracture. The ...
Orthopaedics
Tumors
12dffb5b-cb5f-465d-858b-79190c6d5a6d
The highest volume overload in a paurient due to maximum cardiac output is seen:
During second trimester
At term
After a heavy meal
Immediately after delivery
3d
single
Ans. d. Immediately after delivery The highest volume overload in a paurient due to maximum cardiac output is seen immediately after delivery. "Peripheral vasodilation leading to a decrease in systemic vascular resistance is thought to be the first cardiovascular change associated with pregnancy (induced by progesteron...
Gynaecology & Obstetrics
null
364b074f-caf6-472c-a962-e91382c34ef2
Turcot's syndrome is associated with -a) Duodenal polypsb) Familial adenomatous polyposisc) Brain tumorsd) Villous adenomae) Hyperplastic polyps
a
c
bc
ad
2c
single
Turcot's syndrome is a variant of Familial adenomatous polyposis characterized by - Colorectal polyposis - Brain tumors (Medulloblastoma, Glioblastoma multiforme) The colonic polyps in Turcot's syndrome are fewer and larger than in classic FAP.
Surgery
null
1d211ebf-cd7d-4006-a7e9-98aa50eaa11f
Absolute contraindication to thiopentone:
Cardiotoxicity
Acute intermittent phorphyria
Malignant hyperthermia
Methhemoglobinemia
1b
single
Ans. (b) Acute intermittent phorphyriaMust Know* Thiopentone is C/I in acute intermittent porphyria.* Etomidate is C/I in adrenal insufficiency.* LA which causes meth hemoglobinemia: Prilocaine* Malignant hyperthermia is caused by: Succinylcholine* DOC for malignant hyperthermia: Dantrolene
Anaesthesia
Miscellaneous General Anesthesia
7f1ab325-d85f-4025-b00e-07a22ac03789
A small amount of atropine is added to diphenoxylate in order to:
Suppress associated vomiting of gastroenteritis
Augment the anti-motility action of diphenoxylate
Block side effects of diphenoxylate
Discourage overdose and abuse of diphenoxylate
3d
multi
Atropine is intentionally added to diphenoxylate in fixed dose combinations to intentionally produce the adverse effects. - If the person takes diphenoxylate in large doses to get the euphoria, atropine will produce adverse effects and the person will not abuse the drug.
Pharmacology
Gastro-Intestinal Tract
882ebf42-f087-466c-893a-6626280fcaeb
A case of injury to right brow due to a fall from scooter presents with sudden loss of vision in the right eye. The pupil shows absent direct reflex but a normal consensual pupillary reflex is present. The fundus is normal. The treatment or choice is:
Intensive intravenous coicosteroids as prescribed for spinal injuries to be instituted within six hours
Pulse methyl Prednisolone 250 mg four times daily for three days
Oral Prednisolone 1.5 mg/kg body weight
Emergency optic canal decompression
0a
multi
A i.e. Intensive intravenous coicosteroids as prescribed for spinal injuries to be instituted within six hours A i.e. Intensive intravenous coicosteroids as prescribed for spinal injuries to be instituted within six hours The first line of management of traumatic optic neuropathy is mega dose IV methyl prednisolone wit...
Ophthalmology
null
c343068d-658f-44b2-8e9a-28f0e0a4005d
Which of the following prevent extrusion and lateral tooth movement
Alveolar crest group
Horizontal group
Oblique group
Apical group
0a
single
null
Dental
null
ff7dd22e-0ecd-4df0-9aa3-a195c0206d0a
Chloroquine is used in the treatment of
DLE
Pemphigus
Psoriasis
Nummular eczema
0a
single
null
Pharmacology
null
755a5d68-a4ef-4bce-ae9c-d34ed0be80ab
Which of the following is the site of Venous Thrombosis in Budd Chiari Syndrome?
Infrahepatic inferior vena cava
Infrarenal inferior vena cava
Hepatic vein
Poal vein
2c
single
Budd-Chiari Syndrome (BCS) is an uncommon congestive hepatopathy caused by the obstruction of hepatic venous outflow. Patients may present with acute signs and symptoms of abdominal pain, ascites, and hepatomegaly or more chronic symptoms related to long-standing poal hypeension. The obstruction may be thrombotic or no...
Medicine
null
cc6e5084-d76b-4877-9012-f0c803f1d70d
True about small bowel diverticula-
Contains all the layers of bowel wall
Common in terminal ileum
Surgical treatment is not required
Seen on the mesenteric border
3d
multi
Small bowel is uncommon site for diverticula. In small bowel, duodenum is the most common site followed by jejunum and then ileum. They are mainly acquired type and are false diverticula i.e. their walls consists of only mucosa or submucosa. They are mainly seen at the mesenteric border. Small bowel diverticula can be ...
Surgery
null
30ba9ad5-f44c-4af8-b386-f0cc0dbbb760
Function of Golgi apparatus is
Synthesis of protein
Maturation of protein
Degradation of protein
Sequencing of protein
1b
single
Organization of the Golgi is directed at proper glycosylation of proteins and lipids. There are more than 200 enzymes that function to add, remove, or modify sugars from proteins and lipids in the Golgi apparatus. Membranous vesicles containing newly synthesized proteins bud off from the granular endoplasmic reticulum ...
Physiology
General physiology
a2ea05d8-c927-4b53-9678-5d2f84bb613d
In a 40 years old male thrombus in the common femoral aery is because of -
Atheroma
Thrombangits obliterans
Raynauds disease
Abdominal mass
0a
single
Ans. is 'a' i.e., Atheroma
Surgery
null
9e939bbd-40e4-44f2-8c4d-7028715e80e7
Treatment of choice in central safe perforation is -
Modified mastoidectomy
Tympanoplasty
Myringoplasty
Conservative management
3d
single
There are 2 schools of thought as far as this question is concerned – Some believe that. TOC of central perforation is myringoplasty. TOC of central perforation is conservative management. But according to Turner 10/e, p 285 - central perforation/ tubo tympanic CSOM are both managed conservatively by antibiotics and ...
ENT
null
22362a35-3598-4a88-9ef5-a033c8e05483
Plasmacytoid lymphomas may be associated with increase in
IgG
IgM
IgA
IgE
1b
single
Lymphoplasmacytic lymphoma is a B-cell neoplasm composed of small lymphocytes, plasmacytoidlymphocytes, and plasma cells, which typically affects older adults. There is maturation to plasmacytoid cells, but lacking the features of other lymphomas (pseudofollicles, neoplastic follicles, monocytoid B cells). lymph nodes;...
Pathology
Haematology
4ed3f0ba-f7a5-4cd6-a722-c6e187d45578
A woman consumes several tabs of Amitryptilline (case of amitryptiline poisoning). All of the following can be done except -
Sodium bicarbonate infusion
Gastric lavage
Diazepam for seizure control
Atropine as antidote
3d
multi
Ans. is 'd' i.e., Atropine as antidote o This question is straight forward and you can solve this one, even if you don't know the treatment of TCAs poisoning. As you all know that TCAs cause antichlolinergic side effects, atropine (an anticholinergic drug) cannot be used in TCAs poisoning. Treatment of TCAs Poisoning o...
Pharmacology
null
cef23903-71b8-47dd-a2ca-e49a99b39a45
Best preservative for protozoal cysts is
10 % formalin
Isopropyl alchol
HCL Solution
Naoh solution
0a
single
10 % formalin is ALL - purpose fixative used for preservation of morphology of helminth eggs, larvae, protozoan cysts and coccidian.
Microbiology
null
cd4b3186-97d1-4fdd-9108-5052400f1a82
The Ridley -Jopling classification for leprosy is based on which of the following parameters?
Clinical, bacteriological, immunological
Histopathological, clinical, therapeutic
Histopathological, epidemiological, therapeutics
Histopathological, clinical, epidemiological
0a
single
Ans. a. Clinical, bacteriological, immunological Ridley-Jopling Classification for Leprosy is based on Clinical (skin and nerve involvement), bacteriological (bacteriological/ morphological index in skin and nasal smears) and immunological criteria (Lepromin test).
Skin
null
a70d307f-4877-4273-8cb8-33276953aac7
Pancytopenia with cellular marrow is seen in all except -
Megaloblastic anemia
Myelodysplasia
Paroxysmal Nocturnal hemoglobinuria
G6PD deficiency
3d
multi
null
Medicine
null
b3fd8ae3-c58a-4280-adca-d02122f6918c
By what age a child can make tower of 3 cubes?
15 months
18 months
24 months
28 months
1b
single
15 months - 2 cube tower 18 months - 3 cube tower 24 months - 6 cube tower 36 months - 9 cube tower
Pediatrics
null
df5eba26-f882-4eaa-a0ac-190e4db7b434
Which of the following is FALSE regarding breast cancer during pregnancy?
Axillary lymph node metastases in 75% of affected women
Mammography is sensitivity during pregnancy
Radiation cannot be considered for treatment
Less than 25% of the breast nodules are cancerous
1b
multi
Breast cancer occurs in 1 of every 3000 pregnant women, and axillary lymph node metastases are present in up to 75% of these women. The average age of the pregnant woman with breast cancer is 34 years. Less than 25% of the breast nodules developing during pregnancy and lactation will be cancerous. Ultrasonography and n...
Surgery
null
09209be8-8324-4a45-a3cb-6428a03f8b78
Which of the viruses is not commonly implicated in the pathogenesis of Non-Hodgkin's lymphomas?
Human T-cell leukemia virus-1 (HTLV-1)
Epstein-Barr virus (EBV)
Human herpesvirus-8 (HHV-8)
Cytomegalovirus (CMV)
3d
single
HTLV-1 is associated with adult T-cell leukemia/lymphoma. EBV is found in a subset of Burkitt lymphoma, 30% to 40% of Hodgkin lymphoma (HL), many B-cell lymphomas arising in the setting of T-cell immunodeficiency, and rare NK-cell lymphomas. In addition to Kaposi sarcoma, HHV-8 is associated with an unusual B-cell lymp...
Pathology
Non Hodgkin Iymphoma
17aecbe9-9c27-4320-9850-82c20087b77e
Karlstad studies were held in:
Netherlands
London
Sweden
Finland
2c
single
Since artificial fluoridation is not permitted in Sweden a number of other initiatives were introduced in 1971 as part of the "Karlstad studies" to evaluate the separate and combined effects of different plaque control programs.  The efficacy of professional tooth cleaning was extensively investigated for the first time in th...
Dental
null
73508488-6509-45fb-91f8-a8258ec3036e
All are true regarding Thrombotic Thrombocytopenia Purpurs (TTP), except ?
Normal complement levels
Microangiopathic hemolytic anemia
Thrombocytopenia
Thrombosis
0a
multi
Ans. is 'a' i.e., Normal complement levels All the given options are true in relation to TTP. Because red cells are forced to squeeze through abnormally narrowed small vessels because of thrombi. --> Due to consuption of platelets in formation of platelet thrombi. --> Due to presence of thrombi in CNS microcirculation....
Pathology
null
0667f795-0893-4e1e-b541-fa9fe4688ad1
Urinary retention in child is most commonly caused by -
Metal scab with ulceration
Post.urethral valve
Urethral stricture
Epispadias
1b
single
null
Surgery
null
daf07b41-4081-4250-a888-595f79ccdab6
Mutism is a recognised feature of :
Ganser states
Conversion hysteria
Catatonic Schizophrenia
All
3d
multi
> A. i.e. Ganser state; B. i.e. Conversion hysteria; C. i.e. Catatonic schizophrenia
Psychiatry
null
7ccd20e8-0730-432d-ae6f-ffdf0b717777
In a patient post myocardial infarction developed arrial fibrillation. Subsequently the ECHO showed a mural thrombus. The management is by
Warfarin
Cardioversion
Digoxin
Propranolol
0a
single
(A) Warfarin # Patients with an anterior location of the infarction, severe LV dysfunction, CHF, a history of embolism, two-dimensional echocardiographic evidence of mural thrombus, or atrial fibrillation are at increased risk of systemic or pulmonary thromboembciism.> Such individuals should receive full therapeutic l...
Medicine
Miscellaneous
f1b7bc19-0a26-485e-8695-94dc17aec1e6
Not seen in pellagra -
Diarrhea
Dyspepsia
Dementia
Dermatitis
1b
single
- niacin deficiency results in pellagra. The disease is characterized by diarrhea, dermatitis and dementia. - niacin deficiency is common in maize eating population due to aminoacid imbalance cause by an excess of leucine. - excess of leucine appears to interfere in the conversion of tryptophan to niacin. Reference: Pa...
Social & Preventive Medicine
Nutrition and health
7dd6bfb1-85df-474a-9770-6044a19f9376
Isolated hyperbilirubinemia is classically seen as an adverse effect of:
INH
Rifampin
Pyrazinamide
Capreomycin
1b
multi
Hepatotoxicity due to rifampin alone is uncommon and often consists of isolated hyperbilirubinemia. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 1375
Medicine
null
9cf04321-2b85-4916-bc37-ca8f764cd4e3
Green coloured urine is seen in:
Copper sulphate
Opium
Nitric acid
Phenol
3d
single
Ans: d (Phenol) Ref:Reddy, 27th ed, p. 469In phenol poisoning (carbolic acid) green coloured urine is passed which is called carboluria. Il is due lo the presence of oxidized hydroquinone and pyrocatechol in urine. They are derivatives of phenol. The hydroquinone and pyrocatechol cause pigmentation in the cornea and va...
Forensic Medicine
Toxicology
8569f191-3105-4946-9511-0403b00fce58
Pseudochylous ascites occurs in-
Cirrhosis
Hyperlipidemia
Filariasis
Malignant ascites
3d
single
• Abnormal accumulation in the peritoneal cavity of a milky fluid that resembles chyle. • The turbidity of the fluid is caused by cellular debris in the fluid. • Pseudochylous ascites is indicative of an abdominal tumor or infection. • In some patients the ascitic fluid appears milky because of an excess of chylomicron...
Surgery
null
7b5991f5-e83e-45ec-b347-7591ba168898
Not true about somnambulism among the following is
Low level motor skill/function is present
Sleep walking
Disorder of sleep arousal
Patient consciousness is not preserved
0a
multi
* Somnambulism is an arousal parasomnia consisting of a series of complex behaviours that result in large movements in bed or walking during sleep. * Also called sleep walking, in this condition individual arises from bed and ambulates without fully awakening. * Individuals can engage in a variety of complex behaviours...
Psychiatry
Sleep disorders and eating disorders