id
stringlengths
36
36
question
stringlengths
1
1.57k
opa
stringlengths
1
287
opb
stringlengths
1
287
opc
stringlengths
1
286
opd
stringlengths
1
301
cop
class label
4 classes
choice_type
stringclasses
2 values
exp
stringlengths
1
22.5k
subject_name
stringclasses
21 values
topic_name
stringlengths
3
135
39b2a812-cfbc-41b4-ade6-5434966f206e
Efficiency of pasteurization can be best assessed by?
Oxidase test
Phosphatase test
Catalase test
Indole test
1b
single
Phosphatase test is widely used yo check the efficiency of pasteurizationREF.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE.Editon-21.Page no.-606.
Social & Preventive Medicine
Nutrition and health
6c423d0c-71eb-41b2-8e9f-5c47fde3408f
Most common cause of hypothyroidism in pregnancy is ?
Nutritional
Irradiation
Anti thyroid drugs ie iatrogenic
Anti TPO antibody
3d
single
Ans. is 'd' i.e., Anti TPO antibodyHypothyroidism in pregnancyThe clinical association of hypothyroidism in pregnancy may be due to :First time diagnosis in pregnancyHypothyroid women who either discontinue thyroid therapy or who need larger doses in pregnancyHypehyroid women on excessive amounts of antithyroid drugsWo...
Gynaecology & Obstetrics
null
7a843e6e-51d0-456a-950f-7f0626c43778
Which of the following is true regarding competitive inhibition?
Vmax increases
Vmax decreases
Km increases
Km decreases
2c
multi
Competitive inhibition leads to increase in Km, and Vmax remains constant.
Biochemistry
null
dc531381-d572-4dc8-b7f7-c035ca54115c
A patient was brought to the hospital with a history of A eight hours back. A few drops of blood is noted at the external urethral meatus. He has not passed urine and his bladder is palpable per abdomen. The probable diagnosis is :
Urethral injury
Rupture bladder
Urethral injury with extravasation of urine in the retroperitoneum
Anuria due to hypovolemia
0a
single
Ans. is 'a' i.e. Urethral injury Blood at urethral meatus and urine retention are suggestive of urethral injury.
Surgery
null
2750f818-1a35-4a9b-8873-f056186bc226
Strong correlation is signified by a correlation coefficient of:
Zero
1
Less than 1
More than 1
1b
single
CORRELATION COEFFICIENT (R): Measures the degree or strength of relationship in a correlation (relationship between 2 quantitative or continuous variables). Correlation coefficient (r) lies between: –1 to +1 (–1 < r < +1) Strength of correlation: Weak positive correlation: 0 < r < 0.3 Moderate positive correlation: ...
Dental
null
e87a8e59-da04-43d5-8a08-65916510b7ab
Drug of choice for treating anaphylaxis is:
Adrenaline
Corticosteroid
Antihistaminics
Sodium chromoglycate
0a
single
null
Pharmacology
null
2f0647c1-7f24-4fad-af78-925c5d0f0e4d
The gold standard for the diagnosis of osteoporosis is –
Dual energy X-ray absorptiometry
Single energy X-ray absorptiometry
Ultrasound
Quantitative computed tomography
0a
single
Dual Energy X-ray absorptiometry (DEXA) is the gold standard and investigation of choice for diagnosis of osteoporosis.
Radiology
null
9aea8dc3-8f5b-44fa-85fd-414d0f5adae2
According to ADA Specification No. 28, what is the rate of increase in file diameter per running millimeter of length for a K-type file from point D0 to point D16?
0.02 mm per running millimeter of length
0.04 mm per running millimeter of length
0.06 mm per running millimeter of length
Parallel sided, so no increase in diameter
0a
multi
Each number should represent diameter of instrument in 100th of millimeter at the tip.  For example, a No. 25 K file shall have 0.25 mm at D1 and 0.57 mm (0.25 + 0.32) at D2.  These sizes ensure a constant increase in taper, i.e. 0.02 mm/mm of the instrument regardless of the size.
Dental
null
21e4d5c3-f9d5-421a-a0ad-2d3d001055ec
Auditory pathway passes through
Medial geniculate body
Lateral geniculate body
Reciculate formation
Cerebellar fornix
0a
single
null
Anatomy
null
fa1f92f0-afc9-43ee-9e1a-d313563763b8
All statement is true about modified rapid sequence induction- except-
Rocuronium is used as neuromuscular blocker
Any IV induction agent can be used
Positive pressure ventilation with Bag + Mask is not done
Preoxygenation is not mandatory
3d
multi
Any changes from classical RSI steps is called modified RSI. Today we practice lot of modifications. Instead of thiopentone we can use some other intravenous anesthetic depending upon requirement. We can use instead of succinylcholine rocuronium . Positive pressure ventilation with Bag + Mask is not done Preoxygenation...
Anaesthesia
Neuromuscular Blocker
f5c799fe-c8a5-4fc7-9709-64aea09ba8ef
Goose skin or cutis anserina seen in -
Drowning
Lightening
Strangulation
Fire arm injury
0a
single
Cutis anserina (goose skin) is seen in drowning, especially on exposure to cold water. It is not a diagnostic sign of drowning and this sign is rarely seen in India, water being usually warm.
Forensic Medicine
null
677a68ac-940c-439d-bf13-5f1bda4d24c6
Useful screening test for lead is measurement of
Amino-laevulinic acid in urine
Coproprophyrin in urine
Lead in blood
Lead in urine
1b
single
Diagnosis of lead poisoning:
Social & Preventive Medicine
null
6cd09c09-2c79-4154-acd4-eb1d61d359e1
An IV drug abuser develops an aggressive form of nephrotic syndrome that does not respond to steroids. A renal biopsy is performed. Which of the following histological diagnoses will most likely be made from the biopsy tissue?
Focal segmental glomerulosclerosis
IgA nephropathy
Membranous glomerulonephritis
Membranoproliferative glomerulonephritis
0a
single
Focal segmental glomerulosclerosis Associated with IV drug abuse and HIV nephropathy. Aggressive form of nephrotic syndrome Poor prognosis Non responsive to steroid therapy (called as 'collapsing variant').
Pathology
Nephrotic Syndrome
227a228f-4e6d-49c8-bb59-a7c24add78c7
The current drug of choice in paroxysmal Sypraventricular Tachycardia (PAVT ) is
Digoxin
Dilantoin
Propranolol
Adenosine
3d
single
adenosine is the drug of choice for PSVT. Immediate electrical cardioversion is indicated if the arrhythmia is associated with hemodynamic collapse. Adenosine is the preferred drug in those patients in whom verapamil has failed or may cause adverse effects, such as those with hea failure or wide-complex tachycardia In ...
Medicine
C.V.S
afe18535-2b94-42d4-a20f-41146b79fb29
Anti progesterone drug is :
Cyproterone
Mifepristone
Spironolactone
Tamoxifen
1b
single
Mifepristone
Gynaecology & Obstetrics
null
c6a9a7d9-627b-4b59-99e8-98fab12e9f38
Multiple lytic lesions of skull with beveled edges are seen in –
Eosinophilic granuloma
Metastases
Multiple myeloma
Neuroblastoma
0a
single
Punched out lesions of skull are seen both in Eosinophilic granuloma and multiple myeloma. However, beveled edges (double contour) is characteristic of eosinophilic granuloma due to uneven destruction of the inner and outer table of the skull.            Punched out lesions of skull                    →  Multiple myel...
Radiology
null
604d659c-8bd4-41a1-98a1-28e539b87cb7
Which of the following is a zoonotic disease ?
Hydatid cyst
Malaria
Filariasis
dengue fever
0a
single
Ans. is 'a' i.e., Hydatid cyst Impoant zoonoses I. Bacterial -4 Anthrax, Brucellosis, Ornithoses, Q-fever, Leptospirosis, TB, Plague, Tularemia, Salmonellosis. 2. Viral --> Cowpox, Monkeypox, Easternequine, encephalitis, Ross river fever, Yellow fever, Japanese encephalitis, Lassa fever, Rabies. 3. Protozoal ---> Leish...
Social & Preventive Medicine
null
fc18a3e6-207a-4bad-9ec1-3b2a6ff28fef
Which of the following is not a benign tumor?
Lipoma
Leiomyoma
Hepatoma
Chondroma
2c
single
Ans. c (Hepatoma). (Ref. Robbin, Pathology, 7th ed., 273)BENIGN TUMORS# Fibroma,Lipoma,Chondroma# Osteoma,HemangiomaMeningioma# Leiomyoma,Rhabdomyoma,Squamous cell papilloma# Liver cell adenoma,AdenomaPapilloma# CystadenomaBronchial adenomaRenal tubular adenomaEducational Points:# An ectopic rest of normal tissue--chor...
Pathology
Neoplasia
e0ed73bc-5f9e-43c2-999a-87216cedbe1d
Rokitansky Kuster Hauser syndrome ta associated with :
Ovarian agenesis
Absent fallopian tube
Vaginal atresia
Bicornuate uterus
2c
multi
Vaginal atresia Friends MRKH syndrome is associated with vaginal atresia - as is suggested by "A more common form of vaginal atresia is congenital absence of both uterus and vagina which is also referred to as mullerian aplasia. mullarian agensis or Mayer Rokinstansky - Kuster Hauser Syndrome." ... Williams Gyane. 1/e,...
Gynaecology & Obstetrics
null
6dcb3344-40e0-4aa5-97e7-9713e0262e8a
The most common cause of TMJ ankylosis is:
Trauma
Osteoarthritis
Childhood illness
Rheumatoid arthritis
0a
single
null
Pathology
null
d95ad1e7-f323-493d-92d4-b1f0cc0bcc84
Which of the following drugs required a dose adjustment in patient during radiotherapy in order to present radiation toxicity ?
Vincristine
Dactinomycin
Cyclophosphamide
6-Mercaptopurine
1b
single
Ans. is 'b' i.e., Dactinomycin o Like anthracyclines (doxo and daunorubicin), dactinomycin can also cause radiation recall syndrome and the dose should be adjusted with radiotherapy.
Pharmacology
null
31606a7b-8605-46e8-bc83-b49ec027bcd2
Proteins are linear polymers of amino acids. They fold into compact structures. Sometimes, these folded structures associate to form homo or hetero-dimers. Which of the following refers to this associated form?
Denatured state
Molecular aggregation
Precipitation
Quaternary structure
3d
single
Quaternary structure defines the polypeptide composition of a protein and, for an oligomeric protein, the spatial relationships between its protomers or subunits. Monomeric proteins consist of a single polypeptide chain. Dimeric proteins contain two polypeptide chains. Homodimers contain two copies of the same polypept...
Biochemistry
Structure and function of protein
429c34fe-b313-46eb-a0c3-25dfb8c6178e
True about dementia is: Karnataka 07
Alzheimer's disease is due to multiple small strokes in the cerebral coex
Dementia is the loss of distant memory
Dementia due to atherosclerosis does not progress like Alzheimer's
Alzheimer's disease is associated with an increase in ACh release in the cerebral coex
1b
multi
Ans. Dementia is the loss of distant memory
Forensic Medicine
null
b6f0b264-14fe-4360-8e5f-7ee786a3b7c5
Deep injury of neck always involves
Platysma
Trapezius
Sternocleidomastoid
Longus colli
0a
single
Investing layer lies deep to the platysma and surrounds the neck like a collar. The surgeon has to stitch platysma muscle separately so that skin does not adhere to deeper neck muscles otherwise the skin will get an ugly scar. Ref BDC volume 3;sixth edition pg 81
Anatomy
Head and neck
28f7a6eb-c4c9-4b80-80e2-b0a93ab65941
A female patient after injury comes to casualty. Her ABG shows low pH, pCO2 high, bicarbonate normal. The diagnosis is:
Respiratory alkalosis
Respiratory acidosis
Metabolic acidosis
Metabolic alkalosis
1b
single
Answer is B (Respiratory acidosis) The acid base disorder is respiratory acidosis. There is acidosis (pH : low) Raised pCO2 (acidosis) indicates that the change in CO2 is therefore primary Normal bicarbonate indicates that there is no alteration in the metabolic component The acid base disorder therefore is Respiratory...
Medicine
null
51caac51-a6aa-4398-93e1-7945d3f4082c
Drug of choice for central diabetes insipidus
Vasopressin
Desmopressin
Lypressin
Presselin
1b
single
Ans. is'b'i.e., DesmopressinDesmopressin (intranasal) is the DbC for central DI.
Pharmacology
null
119ed07f-c029-4498-9f57-4e987ae04d1e
Most common cause of End stage renal disease is:
Diabetes
Hypertension
Chronic GN
Polycystic Kidney disease
0a
single
Ref: Harrison's Principles of Internal Medicine. 18ed.Explanation:The dispiriting term end-stage renal disease' should not be used and is replaced by the term stage 5 CKD"The most frequent cause of CKD is diabetic nephropathy. most often secondary to type 2 diabetes melli- tus Ref: HarrisonLeading Categories of Etiolog...
Medicine
Chronic Kidney Disease and Uremia
8227baea-4cf2-4ec6-8c40-9d83a74fe4bb
Presumptive treatment of malaria in a chloroquine resistant area:
Chloroquine + pyrimethamine
Sulphalene + pyrimethamine
Chloroquine + primaquine
Sulphalene 1000 mg
1b
single
Ans. is 'b' ie sulph lene + pyrimethamine Presumptive treatment in Chloroquine resistant areaSingle dose of 25 mg/kg body wt. sulfalene/sulfadoxine and 1.25 mg/kg body wt. Pyrimethamine combination and thereafter tab. Primaquine 0.75 mg/kg body wt.
Social & Preventive Medicine
Communicable Diseases
f2d6a184-7d89-4e77-9997-48fce5ad56c0
In a fetus highest oxygen concentration is found in?
Inferior vena cava
Superior vena cava
Left ventricle
Ascending aoa
0a
single
Among the following options, highest oxygen conc is found in IVC Saturation of Oxygen in fetal structures - Umbilical vein - 80% (PO2 of 30-35 mm Hg ) ( Max. in entire body of fetus ) Inferior vena cava - 70% (PO2 of 26-28 mm Hg) Left ventricle - 65% Right Ventricle - 55-60% Umbilical aery - very low SVC - (PO2 of 12-1...
Pediatrics
NEET Jan 2020
7d45aced-25ca-4836-8005-e926a29a18da
Which is the best initial fluid for resuscitation during the shock state:
Crystalloids
Colloids
Blood
Plasma substitutes
0a
multi
Crystalloids predominantly expand the interstitial and then the intracellular compartment not the intravascular compartment (expansion of intravascular compartment is only transient). This is necessary to replenish the intracellular and interstitial compartment as in a hypovolemic patient, the shock induced homeostasis...
Surgery
null
27ad1851-a8a1-4720-9d4b-f3f5ba1ad872
IL-1 is secreted from which cells
Mast cells
Eosinophils
Macrophages
Neutrophils
2c
single
Tumor necrosis factor (TNF)Interleukin-1 (IL-1)Granulocyte-monocyte colony-stimulating factor (GM-CSF)Granulocyte colony-stimulating factor (G-CSF)Monocyte colony-stimulating factor (M-CSF)These factors are formed by activated macrophage cells in the inflamed tissues and in smaller quantities by other inflamed tissue c...
Physiology
Cardiovascular system
0019cdcf-45ed-4c92-af66-1b0bbf5f47bc
All are in cystinuria except
Cystine
Ornithine
Alanine
Arginine
2c
multi
Cystinuria is one of the inborn errors of metabolism. It is autosomal recessive disorder. The disorder is attributed to the deficiency in transpo of amino acids. Abnormal excretion of cysteine and to a lesser extent lysine, ornithine and arginine. Hence the condition is also known as Cysteine-lysinuriaRef: DM Vasudevan...
Biochemistry
Metabolism of protein and amino acid
e93bcb27-06e5-4104-a266-b2c52c0f8e97
Implantation occurs at the stage of -
Zygote
Morula
Blastocyst
Primary villi
2c
single
null
Anatomy
null
221bdbc8-ac70-4f4a-9cb6-2c7801b68002
Streptococcal Toxic shock syndrome is due to the following virulence factor -
M protein
Pyrogenic exotoxin
Streptolysin O
Carbohydrate cell wall
1b
multi
Option 1 M protein: Mediates adherence to epithelial cells, inhibits phagocytosis Option 2 Streptococcal toxic shock syndrome By S. pyogenes (M serotypes 1 or 3)with hyaluronic acid capsule. Caused by SPE (Streptococcal pyrogenic exotoxin) or Erythrogenic toxin. 3 Types : Type A and C - Superantigens. Type A and C bact...
Microbiology
Systemic Bacteriology Pa 1 (Gram Positive Cocci, Gram Negative Cocci)
d5fdbe7f-b4ac-4c7e-ab00-0f31b040cd50
Which one is not poor prognostic factor for acute pancreatitis:
Hyperglycemia
Hypocalcemia
Raised LDH level in blood
Hyperamylasemia
3d
single
Answer is D (Hyperamylasemia) Serum amylase levels do not form any criteria for prognosis in acute pancreatitis. Hyperglycemia, Hypocalcemia and raised LDH levels are poor prognostic factors according to Ranson's criteria.
Medicine
null
d6f0a1be-8038-4a80-928f-2a813f9fda62
Concomitant administration of this drug with organic nitrates is contraindicated due to marked potentiation of vasodilatory action leading to profound hypotension. This drug is:
Propranolol
Fluoxetine
Hydrochlorothiazide
Sildenafil
3d
single
null
Pharmacology
null
db2909b2-bfb2-4b98-9f27-30905dfdef98
Fungus not isolated in culture ?
Cryptococcus
Dermatophyte
Candida
P. jiroveci
3d
single
Ans. is 'd' i.e., P. jiroveci Culture of fungi Culture media used in mycology are : Sabouraud's glucose agar (most common) Czapek - Dox medium Corn meal agar Culture media are supplemented with chloramphenicol to minimize bacterial contamination and cycloheximide to reduce contamination with saprophitic fungi. Cultures...
Microbiology
null
ea81837e-b331-402e-8fe3-a36927d0e93f
The stability of the ankle joint is maintained by the following, except
Plantar calcaneonavicular (spring) ligament
Deltoid ligament
Lateral ligament
Shape of the superior talar aicular surface
0a
multi
A. i.e. Planter calcaneonavicular ligament Calcaneonavicular/ Spring ligament is most impoant ligament for maintaining the median longitudinal arch of foot but has nothing to do with stability of ankle joint because it is not around ankle joint
Anatomy
null
c2df7fbf-f906-4d35-ae5d-bb51267dc987
Osmoreceptor is located at which site
Anterior hypothalamus
Renal medulla
Carotid body
Atrial chamber
0a
single
null
Physiology
null
bb7fbaff-f870-41e5-80cd-07817e09eb62
45 year old alcoholic male came for deaddiction treatment. He has alcohol induced hepatitis with other blood parameters within normal limits. The drug that should not be chosen for relapse prevention is
Disulfiram
chlordiazepoxide
Naltrexone
Acamprosate
2c
single
NALTREXONE is an OPIOID ANTAGONIST given at a dosage of 50-150mg, should not be used in LIVER DYSFUNCTION ACAMPROSATE is an GABA AGONIST given at a dosage of 666MG TDS, should not be used in KIDNEY DYSFUNCTION Ref.Kaplon and Sadock, synopsis of psychiatry, 11 th edition, pg no.626
Anatomy
Substance abuse
0bc689fa-79aa-4c7c-a0aa-0b40ec013ad4
Which of the following prevent lens opacity by free radical scavenging?
Glutathione
Catalase
Vitamin A
Vitamin E
0a
single
Rediced glutathione is the most impoant anti-oxidant mechanism in lens. Ref: Yanoff ch.501; Biochemistry of Lens p.330; Parson 22nd/e p.261&20th/e p.248; Alder's Physiology 10th/e p.130.
Ophthalmology
Lens
50c7d69d-65db-4432-8369-a4a456f5980d
Brick incinerator is used for ?
Waste sharp
Discarded medicine
Infectious waste
Disposable items
2c
single
Ans. is 'c' i.e., Infectious waste Drum (or field) incinerator and brick incinerator should be used only as a last reso, as it is difficult to burn the waste completely without generating potentially harmful smoke.The option is appropriate only in emergency situations during acute outbreaks of communicable diseases and...
Social & Preventive Medicine
null
a637b1e3-904a-4fa3-a793-77ee43453cee
Pseudomyxoma peritonii is seen in which ovarian cancer?
Serous cystadenocarcinoma
Mucinous cystadenocarcinoma
Brenner Tumor
Fibroma
1b
single
Ans. is 'b' i.e., Mucinous cystadenocarcinoma o Mucinous tumors are multiloculated cysts lined by epithelium resembling the endocervix.o The cut section reveals loculi filled with mucinous contents.o If the tumor ruptures, it may lead to formation of pseudomyxoma peritonei and the viscera showing extensive adhesions.o ...
Gynaecology & Obstetrics
Presentation (Carcinoma Ovary)
ae30b7a1-2912-442e-a319-0214e431a264
The following substance acts as a 'satiety signal' for lipids
Apo-A
HCL
Fastrine
Enterostatin
3d
single
Enterostatin, a peptide that selectively reduces fat intake. It is formed in the intestine by the cleavage of secreted pancreatic procolipase, the remaining colipase serving as an obligatory cofactor for pancreatic lipase during fat digestion. After feeding, enterostatin appears in the lymph and circulation. Enterostat...
Biochemistry
Metabolism of lipid
9a84f938-456c-4356-a3ca-87061d2cc246
All of the following act as cell adhesion molecules, EXCEPT:
Integrin
Selectin
Cadherin
Lecithin
3d
multi
Most adhesion proteins, also called CAMs (cell adhesion molecules), can be classified into four main families: immunoglobulin family CAMs, cadherins, integrins, and selectins. Ref: Robbins 8th edition, Chapter 3.
Pathology
null
adf06ff6-0441-4d61-a1bd-e65b64e0793b
Bacitracin acts on -
Cell Wall
Cell Membrane
Nucleic Acid
Ribosome
0a
multi
Ans. is 'a' i.e., Cell wall Bacitracin acts by inhibiting cell wall synthesis. o Bacitracin is a polypeptide antibiotic. o Other polypeptide antibiotics (Polymyxin B, colistin and tyrothricin) act on cell membrane.
Pharmacology
null
3969b60c-4c8b-40ee-9347-e3905c9b0199
A 55-year-old man presented to his general physician with pain and swelling of his right great toe. He repoed he has had this pain for approximately 2 days and it is getting worse. He also stated that he had a similar episode of this 4 years ago, but in the interim, he has been symptom free. He was given something for ...
Negatively-birefringent needle-shaped crystals.
Negatively-birefringent oval crystals.
Negatively-birefringent rhomboidal shaped crystals.
Positively-birefringent needle-shaped crystals.
0a
multi
Negatively-birefringent needle-shaped crystals are classically found in the diagnosis of gout. Positively-birefringent rhomboidal crystals are diagnostic for pseudogout, or calcium pyrophosphate crystal deposition. The other choices are not diagnostic or commonly occurring combinations.
Surgery
null
32c49e69-4af0-493c-a585-481f2c777373
What is the microscopic finding of cervical mucus during post-ovulatory period?
Shows pattern on drying
Is thick
Is thin and cellular
Is thin and alkaline
0a
single
Dried cervical mucus examined microscopically has characteristic patterns dependent on the stage of the ovarian cycle. Mucus crystallization necessary for the production of the fern pattern is dependent on an increased sodium chloride concentration. Cervical mucus is relatively rich in sodium chloride when estrogen, bu...
Gynaecology & Obstetrics
null
1a44268a-14f5-4c1a-9e2a-dfec9fc4216a
Which one of the following is characteristic of microfilaria of W. bancrofti?
Cephalic space twice as long as broad
Excretory pore prominent
Nuclear column smudged
Caudal end uniformly tapering to a delicate point, and no terminal nuclei present
3d
single
The features of microfilaria of W. bancrofti are: General appearance: Graceful, sweeping curves. Free cephalic space: As long as broad.   Excretory pore: Not prominent:   Caudal end: Uniformly tapering to a delicate point and no terminal nuclei present.   5. Nuclear column: Nuclei discrete; Important points   Microfila...
Unknown
null
15ec2b3d-9257-446f-8ac9-87493c6eecac
Diameter of head mirror
3 inches
3.5 inches
2.5 inches
9 mm
1b
single
null
ENT
null
5e8c8201-ae4f-43b0-8e5a-ff79e533ded1
Most suitable radioisotope of Iodine for treating hypehyroidism is:
V"
1125
I131
1132
2c
single
I131
Radiology
null
612751ea-8c2e-4dda-affd-459eb90d739a
All of the following statements about carbohydrate antigen are true, EXCEPT:
It has lower immunogenicity
Memory response is seen
Cause polyclonal B cell stimulation
Does not require stimulation by T cells
1b
multi
Carbohydrate C -Ag is found in the cell wall of streptococcus pneumoniae. It is independent of T cell response, so memory response is present in the carbohydrate C - Ag. Polysaccharides (carbohydrates) are less immunogenic than protein antigens, but are more antigenic than lipids & nucleic acids. Carbohydrate (Polysacc...
Microbiology
null
07edb824-c0fa-4c45-b58d-c001b291e563
All are true about Neisseria gonorrhea EXCEPT
Gram positive cocci
Causes stricture urethra
Involves seminal vesicals and spreads to epididymis
Drug of choice is Ceftriaxone
0a
multi
null
Medicine
null
04f74156-6101-4d44-86c0-13cf854378b0
A 50-year-old man with aortic stenosis is doing exercise for 11 minutes according to Bruce protocol. Exercise had to be stopped due to fatigue. He had a peak sytolic gradient of 60 mmHg across the aortic valve at rest. What is the best management for this patient?
Medical management
Aortic valve replacement
Aortic valve balloon dilatation to prevent further worsening
Coronary angiography
1b
multi
Ans. b > a (Aortic valve replacement > Medical Management) (Ref: ACC/AHA guidelines; European Cardiology Society Guidelines: http:// circ. ahajountals.org/ content/ 122/17/ 1734.full.pdf+html; Braunwald's Heart Disease: 9/e p1474)The patient in question has asymptomatic aortic stenosis but develops symptoms on exercise...
Medicine
C.V.S.
979b13c1-124d-416e-980c-c6752b576694
False about disaster management
Response in pre-disaster phase
Mitigation in pre-disaster phase
Gastroenteritis is commonest infection after disaster
Yellow color is for medium priority
0a
multi
null
Social & Preventive Medicine
null
28d6ee2a-c727-4944-81ed-3f38ccbc8167
Following are causes of unconjugated hyperbilirubinemia except
Hemolytic anemia
Large hematoma
Rotor syndrome
Megaloblastic anemia
2c
multi
Rotors is conjugated hyperbilirubinemia. Others are unconjugated hyperbilirubinemia. Reference: davidson, 23rd edition, page 860
Medicine
G.I.T
2d2b4ff8-7f6c-4eed-86ff-cdc42586d0c2
Which of the following is a non-Iodine containing contrast?
Gadolinium
Visipaque
lopamidol
Diatrozoate
0a
single
Ans. a. Gadolinium (Ref: Grainger 5/e p32-51, 1249-1253; Sutton 7/e p419-421; Wolfgang 7/e p1147)Gadolinium is a non-iodine containing contrast."Gadolinium is a lanthanide. Gd-DTPA is classified as an acyclic, ionic gadolinium contrast medium Its paramagnetic property reduces the T1 relaxation time. Gadolinium based ag...
Radiology
Contrast agents
ad730709-0b5b-4bcd-87d7-94843340172d
Incubation period of chancroid is
Less than 7 days
10-15 days
2-3 weeks
3-4 weeks
0a
single
null
Social & Preventive Medicine
null
090008b6-1306-4e7b-967f-0683dac64ce1
Volume of distribution is NOT affected by all EXCEPT
Binding to plasma protein
Drug clearance
Lipid insolubility
Absence of blood brain barrier
0a
multi
(Binding to plasma protein) (31-33-KDT 6th)* The extent of distribution of drug depends on* Lipid solubility* Ionization at physiological pH (dependent on pKa)* The extent of binding to plasma and tissue proteins* Differences in regional bloodflow
Unknown
null
dfb4598a-14da-4e1f-97f8-2abd89ff22f0
Cough is an adverse reaction with intake of ?
Enalapril
Prazocin
Nifedipine
Thiazide
0a
single
Ans. is 'a' i.e., Enalapril Bradykinin and substance P are also substrate (in addition to angiotensin - I) for ACE. By inhibiting ACE, enalapril inhibits degradation of Bradykinin and substance Pin the lung, which are responsible for cough and angioedema.
Pharmacology
null
5d111830-d9d5-4e2c-86a4-f6eb3579ddc8
Drug acting on V2 receptors and used in DI (REPEAT)
Telypressin
Vasopressin
Desmopressin
Pralispressin
2c
single
Desmopressin is USED IN central DIREF:KDT7/e p597
Pharmacology
All India exam
a0a9c464-b050-43b1-bdaa-cb2555be090a
Function of Topoisomerases
Deoxynucleotide polymerization
Relieve torsional strain
Initiates synthesis of RNA primers
Prevent premature reannealing of dsDNA
1b
single
Classes of Proteins Involved in ReplicationProteinFunctionDNA polymerasesDeoxynucleotide polymerizationHelicasesATP -driven processive unwinding of DNATopoisomerasesRelieve torsional strain that results fromhelicase-induced unwindingDNA primaseInitiates synthesis of RNA primersSingle-strand bindingproteins (SSBs)Preven...
Biochemistry
Structure and function of protein
60085cb5-ea46-4d89-8da2-16f45ed36667
Anemic hypoxia is seen CMC (Vellore) 14
CO poisoning
CO2 poisoning
HCN poisoning
Nerve gas
0a
single
Ans. CO poisoning
Forensic Medicine
null
e87284bc-9f63-42f5-9cc4-a88bf766a563
A child presents with failure to thrive to pediatrics OPD. The doctor counseled the parents about improving nutrition of child , to which mother strongly asseed that they have ensured everything is perfect from their side especially nutrition, but to no avail. Then doctor requested for few investigations. What is the d...
Ebstein anomaly
Ostium secundum, type of ASD
Ostium primum, type of ASD
sinus venosus, type of ASD
1b
multi
Echocardiographic findings in secundum atrial septal defect. Two-dimensional echocardiogram (apical 4-chamber view) shows a moderate-sized secundum ASD. A child with an ostium secundum ASD is most often asymptomatic; the lesion is often discovered inadveently during physical examination as conveyed in the above questio...
Unknown
Integrated QBank
663d5c31-da1d-49cc-afe2-5b2cf07ffbd1
Genital was are caused by which virus?
Herpes simplex
Human papilloma
Cytomegalovirus
Varicella zoster
1b
single
Genital was are soft growths that appear on the genitals. Genital was are a sexually transmitted infection (STI) caused by ceain strains of the human papillomavirus (HPV). These skin growths can cause pain, discomfo, and itching REF : THOMAS HABIF 6TH ED
Dental
All India exam
ff7cfc4e-d381-4c04-98c7-64e251f80af5
Clinical manifestations of Lesch-Nyhan syndrome is due to the defective recycling of the following:
Purines
Methylcobalamin
Pyrimidines
Thiamine
0a
single
Lesch-Nyhan syndrome is a genetic disease, affecting almost solely males, of excessive synthesis of purines because of defective recycling and, therefore, uric acid production from their breakdown. Lesch-Nyhan syndrome is characterized by gouty ahritis but, in addition, affects the brain, resulting in mental retardatio...
Biochemistry
null
8bdcb749-c1ed-4d25-b996-20c70919c5c9
Web constriction is seen in which pa of esophagus, in Plummer-Vinson syndrome
Thoracic
Abdominal
Cervical
Any of the above
2c
multi
Predominantly, it affects females past 40 years. Barium swallow shows a web in the postcricoid region and the same can be seen on oesophagoscopy. (Ref: Textbook of diseases of ENT, PL Dhingra, 7th edition, pg no. 388)
ENT
Oral cavity & Oesophagus
761fd36f-8a50-47d5-8f0e-f5b50ea909df
Warfarin anticoagulants inhibits following coagulation factors :
II, V, VII, IX
II, VII, IX, X
II, V, IX, X
II, IX, X, XIII
1b
single
null
Pharmacology
null
1bfc8e1e-136f-4e58-b622-c12ee7487abd
Which terminal plane is favorable for E/E to have class I molar relationship?
Flush terminal plane
Mesial step
Distal step
None of the above
1b
multi
null
Dental
null
28d85333-b1a0-4a33-a437-9871e72ac68c
Granulomatous uveitis is seen in:
Vogt-Koyanagi-Harada disease
Fuch's disease
Bechet's syndrome
All
0a
multi
A i.e. Vogt-Koyanagi-Harada disease - Granulomatous uveitis is seen in chronic tuberculosis, leprosy, brucellosis, syphilis, leptospirosis, as well as most viral (esp herpes simplex, herpes zoster & varicella), fungal, protozoal and helminthic infectionsQ. It is also seen in sarcoidosis, sympathetic ophthalmitis, Vogt-...
Ophthalmology
null
2c5a843e-0926-4e79-98fd-69e4a616e1e8
Type of fibroadenosis most likely to undergo malignant change is -
Adenosis
Epitheliosis
Sclerosing adenosis
Cystic
1b
single
null
Surgery
null
b7819b96-5708-4994-b4c8-1827e9f29baf
A 36 years old factory worker developed itchy annular scaly plaques in both groins. Application of a caicosteroid ointment led to temporarY relief but the plaques continued to extend at the periphery. The most likely diagnosis is -
Erythema annulare centrifugam
Granuloma annulare
Annular lichen planus
Tinea cruris
3d
multi
Itchy annular lesion in groins with scaling and peripheral spreading and central clearing indicates tinea cruris initially tinea responds to coicosteroids due to masking of infection by steroid effect. iadvl textbook of dermatology, page page 253
Dental
Bacterial infections
7d9740d8-0f45-436c-aa99-ba5d6cd27432
A 45 yr old woman has increasing abdominal girth for the past 2 years. On physical examination, She has abdominal distension. CT scan shows multiple nodules on peritoneal surfaces along with low attenuation mucinous ascites. Cytological examination was done after doing paracentesis. It showed well differentiated column...
Pancreas
Ileum
Jejunum
Appendix
3d
single
Pseudomyxoma pertonei is being described. It may arise from low grade mucinous adenocarcinoma of the appendix. Mucinous tumors may also arise in pancreas, but are less likely to disseminate through peritoneal cavity. These tumors are very rare in small intestine. Mucin producing malignancies of the stomach are most lik...
Pathology
null
314baaf6-0aea-4ae6-a54c-b357b8852b1b
USG done at 18-20 weeks mainly to:
Detect fetal abnormality
Determine sex
Estimate liquor
Determine maturity
0a
single
A i.e. Detect fetal abnormality
Radiology
null
db531341-7006-40fd-88bc-a26f247f2a2c
All of the following are features of acromegaly,except -
Glucose intolerance
Nonsuppressibility of growth hormone by glucose ingestion
Raised levels of plasma somatomedin D
Low serum phophate
3d
multi
null
Medicine
null
6ebb3b99-136f-40e0-bf52-dfa7b4f90854
Mental retardation is defined when I.Q. is below :
90
80
70
65
2c
single
C i.e. 70
Forensic Medicine
null
008ebe70-eb23-4733-81af-1759261566ad
In which of the following, interpretation of benefits is done in terms of results achieved: September 2010
System analysis
Cost accounting
Cost benefit analysis
Cost effective analysis
3d
single
Ans. D: Cost effective analysis Cost-effectiveness analysis (CEA) is a form of economic analysis that compares the relative costs and outcomes (effects) of two or more courses of action. Cost-effectiveness analysis is distinct from cost-benefit analysis, which assigns a monetary value to the measure of effect. Cost-eff...
Social & Preventive Medicine
null
7baba0dd-c85a-44bc-b38f-76ceaf3f2065
Skin test are used for which hypersensitivity reactions?
I
II
III
IV
0a
single
Type I hypersensitivity reaction is IgE dependent. When a small shocking dose of an antigen is administered intradermally to a sensitised host, there will be a local wheal and flare response. This is cutaneous anaphylaxis. Cutaneous anaphylaxis ( skin test for typ I hypersensitivity ), is useful in testing for hypersen...
Microbiology
Immunology
68cfbcb3-2bca-4353-bcf4-59bbdaebd411
A Bone marrow transplant recipient patientdeveloped chest infection. On HRCT 'Tree in bud appearance' is seen. Most likely causative agent is:
Klebsiella
Pneumocystis
TB
RSV
1b
single
Pneumocystis [Ref: Harrison I7/e p843; Aicle 'Tree in bud sign' in Journal 'Radiology' and 'Radiographics7 Tree-in-bud is a sign seen in HRCT, most commonly seen with endobronchial spread of Tuberculosis, but can be seen with a wide variety of conditions, most commonly infections. (Described ahead in detail). Theoretic...
Surgery
null
e9c60d9f-aecb-4626-a6e5-f8364cd354ce
Secondary (AA) amyloid is seen in all except ?
RA
TB
Multiple myeloma
RCC
2c
multi
Ans. is 'c' i.e., Multiple myelomao In Multiple myeloma the amyloidosis is AL type (primary amyloidosis).
Pathology
null
88a8dc07-3999-4d22-9b83-54b0f3bedfc4
Large bowel Colonic Diarrhoea is associated with all of the following, except:
Large Volume Stool
Urgency
Tenesmus
Mucus
0a
multi
Answer is A (Large Stool Volume): Large Bowel Colonic Diarrhoea is typically associated with frequent small volume stools since reservoir capacity of the bowel is reduced. Right-sided (Small Bowel) diarrhea is characterized by large-volume stools. The increase in the number of stools is modest and symptoms attributed t...
Medicine
null
2ab97b92-9c5a-4d0f-bdd1-30f87070aa80
A 20 year old girl, presents with 9 month history of neck swelling with thyrotoxic symptoms. On investigation, increased T4 and decreased TSH with palpable 2 cm nodule was found. Next investigation will be:
USG
Thyroid scan
Radioactive iodine uptake
CT scan
1b
single
null
Surgery
null
e5cd0f45-a845-4747-8852-47f4455c1d82
Polycarboxylate cement is used for:
Temporary restoration
Luting
Permanent restoration
Die material
1b
single
ZINC POLYCARBOXYLATE CEMENT APPLICATIONS: Primarily for luting permanent restorations. As bases and liners. Used in orthodontics for cementation of bands. Also used as root canal fillings in endodontics. Ref: Manappalil P: 95
Dental
null
63bf4a9d-8f28-4ae8-a3b3-d5bee8e18175
'Stomach bowel test' is also known as
Hydrostatic test
Breslau's first life test
Breslau's second lfe test
Raygat's test
2c
single
Live-born infant swallows air into the stomach during respiration, and if present in small intestine it fuher confirms live bih. But air may be present in the stomach after decomposition, or in the stillborn attempting to free the air passages of fluid obstruction. Demonstration: The stomach and intestines are removed ...
Forensic Medicine
Sexual offences and infanticide
e0e53de8-6c92-419f-9ee7-1c7f93fe48b8
Maintenance of the corpus luteum during the first trimester of pregnancy is accomplished principally by the secretion of ?
Antidiuretic hormone (ADH)
Follicle stimulating hormone (FSH)
Human chorionic gonadotropin (hCG)
Luteinizing hormone (LH)
2c
multi
The corpus luteum secretes estrogens, progesterone, and relaxin. hCG, secreted by the syncytiotrophoblast lining the placental villi, maintains the corpus luteum during the first trimester of pregnancy. Antidiuretic hormone (vasopressin does not play a significant role during pregnancy. FSH acts on granulosa cells to p...
Physiology
null
ee8c912f-9819-44a9-a252-8de850213b08
The tube as shown in PLATE X-11 is in which space?
Pericardial cavity
Pleural space
Mediastinum
Lung parenchyma
1b
single
ANSWER: (B) Pleural spaceREF: Sabiston 18th ed chapter 57See PLATE X-11 Key PLATE X-11 KeyINTERCOSTAL CHEST TUBE DRAIN (TUBE THORACOSTOMY)A chest tube can be a diagnostic procedure as well as a therapeutic oneINDICATIONS FOR CHEST TUBE DRAIN INSERTION1. Pneumothorax2. In any ventilated patient3. Tension pneumothorax af...
Surgery
Miscellaneous (Lung)
e05ae094-512d-4ed1-9387-6342fc2b1a6e
Nerve supply of tympanic membrane-a) Auriculotemporalb) Auricular branch of vagusc) Occipital nerved) Great auricular nervee) Glossopharyngeal nerve
abe
bcd
cde
acd
0a
single
null
ENT
null
e5893734-1fe0-4c8b-aecb-16bd4cafc29f
Telmisartan lowers blood pressure by:
Inhibiting formation of angiotensin I to angiotensin II
Inhibiting conversion of renin to angiotensin I
Blocking AT1 receptors
Interfering with degradation of bradykinin
2c
single
null
Pharmacology
null
5087acbf-cf2f-4e1a-a0a8-156b6401f239
Best treatment of tension pneumothorax is -
Immediate letting out of air
Wait and watch
Rib resection
Underwater drainage
0a
single
Ans. is 'a' i.e., Immediate letting out of air Tension pneumothorax must be treated as a medical emergency. If the tension in the pleural space is not relieved, the patient is likely to die from inadequate cardiac output or marked hypoxemia. A large-bore needle should be inseed into the pleural space through the second...
Surgery
null
df4e1d4b-37be-4d37-a968-996bff96928b
Viper bite resembles poisoning by -
Semicarpus anacardium
Abrus precatorius
Ricinus communis
Capsicum annum
1b
single
Ans. is 'b' i.e., Abrus precatorius * Abrus precatorius seed is odourless, tasteless, oval (egg shaped), bright scarlet coloured with a black spot at one pole and contain abrin, a toxalbumin as its active principle, which is similar to viper snake venom.* Raw or cooked seeds, when swallowed are non-poisonous. But if ex...
Forensic Medicine
Toxicology
6cd9c2b5-aadf-4225-b30f-db07bd43276a
Two weeks after birth, a baby has persistent tachypnea, tachycardia, diaphoresis, and cyanosis. Workup reveals a patent ductus arteriosus. This can be closed with the use of:
Indomethacin
Acetaminophen
Aspirin
Cyclosporine
0a
single
The nonsteroidal anti-inflammatory drug, indomethacin, is the drug of choice for closure of a patient ductus arteriosus in a premature infant with an isolated patient ductus arteriosus. For complex cardiac anomalies, which require a patient ductus arteriosus to sustain life until corrective surgery can be done, prostag...
Surgery
Miscellaneous
bf8a5b8f-6e74-4632-a4b5-c92bef5bc4fc
Dead Layer of epidermis-
Stratum basale
Stratum spinosum
Stratum corneum
Stratum granulosum
2c
single
Stratum corneum the outermost layer of the epidermis made up of terminally differentiated, dead keratinocytes known as corneocytes. Corneocytes are devoid of cytoplasm and organelles, but loaded with keratin filaments in an amorphous protein matrix, which is held together by the cornified envelope. Ref Harrison20th edi...
Dental
Anatomy of skin
50b4aecb-4b2e-4f7d-aedb-af9013113ed4
The chloride shift occurs rapidly and is essentially completes in
1 second
2 seconds
5 seconds
60 seconds
0a
multi
Chloride ShiftSince the rise in the HCO3- content of red cells is much greater than that in plasma as the blood passes through the capillaries, about 70% of the HCO3- formed in the red cells enters the plasma.The excess HCO3- leaves the red cells in exchange for Cl-, a process mediated by Band 3, a major membrane prote...
Microbiology
All India exam
9403525e-b315-4b13-bf78-c69c9be1460e
Which one of the following is a tyrosine tRNA analogue that causes premature chain termination?
Cycloheximide
Puromycin
Paromomycin
Erythromycin
1b
single
Puromycin Structural analogue of tyrosinyl tRNA. Incorporated into nascent protein chains by a nonhydrolyzable peptide bond. Growing of the peptide bond is inhibited. Inhibits protein synthesis in both prokaryotes and eukaryotes Causes premature chain termination
Biochemistry
Translation
7c75d933-4869-4cb5-8b9a-2d38feb83af3
Macrocytic anaemia occurs in all,except -
Thiamine deficiency
Liver disease
Orotic aciduria
Copper deficiency
3d
multi
null
Medicine
null
ee725b7b-ff29-4b4d-ad6f-229d98214038
Which of the sulfonylureas is best choice in chronic kidney disease patients
Glimipride
Glibenclanide
Glipizide
Glyburide
2c
single
Glipizide is the sulphoylurea which is the best and safest among the group for use in ckd patients Ref: Harrison page no 2265,
Medicine
Endocrinology
bcbd14b5-ae79-4b47-956b-8e7d60a4e90e
Florence test is used for
Blood
Semen
Urine
Albumin
1b
single
Ans. (b) SemenRef,: The Essentials of FSM by K.S. Narayan Reddy 31st ed. / 405Tests for Detection ofSeminal Stain (Mnemonic- "Creat Acid Fast Bacilli')* Acid phosphatase test: to detect Aspermia cases* BarberioS test: to detect Spermine (yellow needle shaped spermine picrate)* Creatine phosphokinase test: for old semin...
Forensic Medicine
Biological Materials & Stains
4452d3fb-b9fd-438d-b2d6-b70cb4fd4eb3
All are seen in cystitis EXCEPT:
Fever
Hematuria
Dysuria
Nocturia
0a
multi
ANSWER: (A) FeverREF: Smith urology 17th ed page 206Acute cystitis refers to urinary infection of the lower urinary tract, principally the bladder.Acute cystitis more commonly affects women than men.Patients with acute cystitis present with irritative voiding symptoms such as dysuria, frequency, Nocturia and urgency,Lo...
Surgery
Miscellaneous (Bladder)
c33c2992-ae9e-41c7-8f34-fef69e35bb67
Population covered by anganwadi in tribal area is?
1000
300
400
700
3d
single
Ans. is 'd' i.e., 700 "According to the existing norms of the government there should be one unganwadi per 1000 population in rural and urban areas, and one anganwadi per 700 population in tribal areas"
Social & Preventive Medicine
null
de1b91a8-2619-443b-a406-970fd333f2f7
Bisected pearls appearance on culture medium is seen in ?
Brucella
Bordetella
Haemophilus ducreyi
Pseudomonas
1b
single
Ans. is 'b' i.e., Bordetella Bordetella are gram-negative, capsulated, fimbriated, nonmotile coccobacillus.They show bipolar metachromatic granules on staining with toluidine blue.
Microbiology
null