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135
c54ace25-5da5-4215-ab7d-a38109f67af4
Osmotic fragility is increased in ?
Sickle cell anaemia
Thalassemia
Hereditary spherocytosis
Chronic lead poisoning
2c
single
Ans. is 'c' i.e., Hereditary spherocytosis Osmotic fragility of Red blood cells. Red blood cell osmotic fragility is the resistance of RBC hemolysis to osmotic changes. o Normally RBC maintains osmotic equilibrium with the surrounding medium i.e., with serum that has 0.9% NaCl. o As the surrounding medium becomes hypot...
Pathology
null
6e9d73be-adf4-402b-8c33-4c04fc394a07
Which drug is not used to prevent contrast nephropathy -
Fenoldopam
N-acetylcysteine
Infusion of Hair normal saline
Hemodialysis
0a
single
Ans. is 'a' i.e., Fenoldopam Summary And Recommendations for prevention of contrast induced nephropathy (uptodate recommendation )o Optimal therapy to prevent contrast-induced acute renal failure remains uncertain. Patients with near-normal renal function are at little risk and few precautions are necessary other than ...
Medicine
Drugs
9063e3de-5630-4b5d-8a5e-d86952102c4c
Aminoacyl t-RNA is not require for -
Proline
Lysine
Hydroxy lysine
Methionine
2c
single
Ans. is 'c' i.e., Hydroxylysine o The initial step in protein synthesis is the activation of amino acid in which each of the 20 amino-acids is covalently attached to their respective t-RNA, forming specific amino acyl t-RNA.o The reaction is catalyzed by ami noacyl t-RNA synthase.o Hydroxyproline and hydroxylysine are ...
Biochemistry
Amino Acids Basics
0a875738-183d-47f9-9cd4-46ed028279f3
Intermediate host for hydatid disease:
Man
Dog
Cat
Foxes
0a
single
Man
Microbiology
null
ad019ad8-9ecd-469e-933b-da97560a1349
Episodes of depression in major depressive disorder tend to:
Increase in frequency with age
Decrease in length with age
Last for about 9 months when treated
Have a rapid onset
0a
single
Episodes of major depression tend to increase in both length and frequency with age. When treated, episodes of major depression last for about 3 months. If untreated, depression lasts from 6 to 12 months. Episodes of major depression often have a gradual onset and occur an average of 5 to 6 times over a 20-year period.
Psychiatry
null
17b0da8b-caee-45ea-9455-59a897d0fa73
Which of the following does cause epidemic kerato conjuctivitis -
Adenovirus
Enterovirus
Coxsakie virus
Herpes virus
0a
single
adeno virus cause epidemic keratoconjuctivitis REF:<\p> MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.482
Microbiology
Virology
33653d43-6214-4175-b026-c93cfa645e7b
Sacrococcygeal teratoma is associated with:
Meningocele
Cardiac detects
Hepatic cysts
Cystic adenoid malformation
0a
single
Ans: A (Menigocele) Ref: Robbins and Cotran Pathologic Basis of Disease: 8th editionExplanation:Sacrococcygeal TeratomasMost common teratomas of childhoodAccounts for 40% or more of casesFour times more common in girlsApproximately 10% of sacrococcygeal teratomas are associated with congenital anomaliesPrimarily defect...
Surgery
Miscellaneous (Neoplasia)
7ddfa638-0a38-4f7f-a30c-b3469addea92
Which poisoning causes 'pink disease'?
Arsenic
Mercury
Copper
Lead
1b
single
Ans. is 'b' i.e. Mercury Pink disease or Acrodvniao It is thought to be an idiosyncratic hypersensitivity reaction particularly seen in children. This can be caused by chronic mercury exposure in any form usually in children. The onset is insidious with anorexia, insomnia, sweating, skin rash and photophobia. Hands and...
Forensic Medicine
Forensic Toxicology - Concepts, Statutes, Evidence, and Techniques
6ced785b-413c-4df8-8ce8-aa579c6d9521
What is the treatment of threshold ROP?
laser photocoagulation
slow reduction in oxygen
retinal reattachment
antioxidants
0a
single
Ans is 'a' i.e. Laser Photocoagulation Threshold disease in ROP is defined as stage 3+ ROP in Zones 1 or 2 occupying at least five contiguous clock-hours or eight noncontiguous clock-hours of retina.Treatment of threshold disease is Laser Photocoagulation.'Laser therapy has largely replaced cryotherapy because visual a...
Ophthalmology
Dystrophies and Degenerations
6151d0b8-8f10-4375-ad6b-c8ceda5cecee
Diplopia is usually seen in ?
Paralytic squint
Non-paralytic squint
Both of the above
None of the above
0a
multi
Ans. is 'a' i.e., Paralytic squint
Ophthalmology
null
783c7c1e-1433-404c-9ff9-8d1e773bbd13
Which is the most common lymphoma in adults?
Adult T-cell leukemia/lymphoma (ATLL)
Hodgkin lymphoma
Diffuse large B-cell lymphoma (DLBCL)
Follicular lymphoma
2c
single
DLBCL - Most common lymphoma in adults Follicular lymphoma - Most common indolent lymphoma in adults Chronic lymphocytic leukemia - Most common leukemia in adults
Pathology
Non Hodgkin Iymphoma
3a5e5f71-377d-4104-ac1c-2b86d75b2ece
Mooning is a form of
Exhibitionism
Transvestism
Voyeurism
Eonism
0a
single
Flashing: The act of momentarily exposing or revealing sexual body pa by quickly moving the clothing. Streaking: The act of running naked through a public place. Mooning: The act of displaying one's bare buttocks, by lowering the pants and bending over
Forensic Medicine
Sexual offences
da1ae1cd-24a5-42c1-8d1f-a980bda9e921
All are seen in vitamin C deficiency except:
Swollen bleeding gums
Delayed wound healing
Anemia
Infeility
3d
multi
Vitamin C/Ascorbic acid deficiency leads toScurvy Clinical manifestation of scurvy: Swollen and bleeding gums Subcutaneous bleeding and brushing into skin/joints Delayed wound healing Anemia Weakness.
Social & Preventive Medicine
Vitamins and Nutritional Deficiencies
18a6981c-d029-4302-983d-47afaa422dfe
A person had injury to right upper limb he is not able to extend fingers but able to extend wrist and elbow. Nerve injured is -
Radial
Median
Ulnar
Posterior interosseus
3d
single
Posterior interosseous emerges from the supinator on the back of the forearm .Here it lies between the superficial and deep muscles.At the lower border of the extensor pollicis brevis, it passes deep to extensor pollicis longus.it then runs on the posterior surface of the interosseous membrane up to the wrist where it ...
Anatomy
Upper limb
98962868-b39b-4f72-8a54-79cce3221fba
The patient with least risk of pulmonary aspiration of gastric contents during induction of anesthesia is:-
Markedly obese and NPO for eight hours
Fed coffee four hours before elective surgery
Scheduled for elective cesarean delivery and NPO for 20 hours
NPO for four hours after a full meal
0a
single
NPO is same for obese and normal. NPO guidelines - 6hrs for liquid and semisolid, 2 hours NPO for clear fluids. Subset of patients who are at high risk for aspiration - pregnant women, morbidly obese (rapid sequence induction), full fatty meal - 8 hours NPO.
Anaesthesia
JIPMER 2019
458caac4-b90f-47d7-939d-934e9a724f5e
Which of the following enzyme uses citrate in fatty acid synthesis?
Aconitase
Citrate synthase
Malic enzyme
ATP citrate lyase
1b
single
Reference: Harpers illustrated biochemistry 30th edition
Biochemistry
Structure and function of protein
b9c5bea0-b253-4907-8e7e-c3945589c4f7
Which of the following changes does not occur in malignant hypeension :
Peticheal Haemorrhages on coical surface
Fibrinoid necrosis of aerioles
Intimal concentric thickening
Hyaline aeriosclerosis
3d
single
Answer is D (Hyaline Aeriosclerosis) : Hyaline aeriosclerosis is a feature of Benign Nephrosclerosis associated with benign phase of Hypeension. It is not a ,feature of Malignant Hypeension.
Medicine
null
d1081012-1be8-4319-9bf2-7d2438593c88
Which of the following nerves has the best prognosis for repair after injury -
Ulnar
Radial
Median
Lateral popliteal
1b
single
Ans. is 'b' i.e., Radial nerveRecovery potential after nerve repairExcellent :- Radial, Musculocutaneous, femoral, digital nervesModerate :- Median, Ulnar, TibialPoor :- Common peroneal (lateral popliteal)
Orthopaedics
Radial Nerve Injury
8efc285f-673d-4fab-ab18-aa4922f36e9b
Treatment in post operative shivering?
Pethidine
Piritramide
Methadone
Pentazocine
0a
single
Ans. is 'a' i.e., Pethidine Post-anaesthesia shivering (PAS) Post anaesthesia (post operative) shivering occurs in 40% of patients recovering from general anaesthesia. Some time it is preceded by central hypothermia and peripheral vasoconstriction, indicating that it is a thermoregulatory mechanism Pethidine is most ef...
Anaesthesia
null
db9f1bea-9ad6-4037-9995-355eb0840177
Birbeck’s granules in the cytoplasm are seen in:
Langerhans cells
Mast cells
Myelocytes
Thrombocytes
0a
single
Birbeck granules are rod Shaped/Tennis-racket shaped cytoplasmic organelles with a central linear density and a striated appearance. They are diagnostic microscopic feature in Langerhans cell histiocytosis (Histiocytosis X)
Pathology
null
3452b1d3-b750-4d40-ae9e-79a1a0c6dddf
Crural index is:
Length of tibia/femur x 100
Length of radius/humerus x 100
Length of fibula/tibia x 100
Length of radius/ulna x 100
0a
single
Ans. Length of tibia/femur x 100
Forensic Medicine
null
0473aeb8-a083-4cca-ac55-c0cdba0c6f03
Primordial prevention is done to prevent development of ?
Disease
Risk factors
Impairment
Disability
1b
single
Ans. is 'b' i.e., Risk factors LEVELS OF PREVENTION There are four levels of prevention :? Primordial prevention Primary prevention Secondary prevention Teiary prevention Primordial Level of Prevention: Is primary prevention (see below) in purest sense It is the prevention of the emergence or development of risk factor...
Social & Preventive Medicine
null
11c4dd07-1c91-47b8-8b9f-f9182ac9e5b1
Anakinra is a -
IL - 1 antagonist
IL - 2 antagonist
IL - 6 antagonist
IL - 10 antagonist
0a
single
Ans. is 'a' i.e., IL-1 antagonisto Anakinra is an IL-1 antagonist.o It is used for some rare syndromes dependent on IL-1 production :Neonatal - onset inflammatory diseaseMuckle - Wells syndromeFamilial cold urticariaSystemic juvenile - onset inflammatory arthritisRA
Pharmacology
Immunomodulator
d45904aa-fb66-473e-9f80-037a0932d06e
The gold standard for the definitive diagnosis of the extrahepatic biliary atresia is
Per operative cholangiography
Hepatobiliary scintigraphy
Alkaline phosphatase level
Liver biopsy
3d
single
Biliary atresia Evaluation of biliary anatomy begins with ultrasound Other imaging modalities such as HIDA scintigraphy, MRCP and ERCP have been used with varying success Although these are useful adjuncts, liver biopsy is gold standard for the diagnosis of biliary atresia and can safely be done percutaneously under lo...
Anatomy
G.I.T
f1afc5be-dfe8-4034-8e52-69005f63e542
All of the following passes through lesser sciatic foramen, except ?
Pudendal nerve
Internal pudendal vessels
Nerve to obturator internus
Inferior gluteal vessels
3d
multi
The lesser sciatic foramen is formed by the lesser sciatic notch of the pelvic bone, the ischial, the sacrospinous ligament and the sacrotuberous ligament. It transmits the following structures: The tendon of the Obturator internus Internal pudendal vessels Pudendal nerve Nerve to the obturator internus
Anatomy
null
9f78aa57-fa01-4142-8b6b-0c29dd2d57ba
Increased osmotic fragility is characteristic of:September 2009
Hereditary spherocytosis
Sickle cell anemia
Thalassemia
Iron deficiency anemia
0a
single
Ans. A: Hereditary spherocytosisThe normal red blood cell is a relatively impermeable biconcave disc which maintains osmotic equilibrium with the surrounding medium. As the surrounding medium becomes hypotonic, fluid will be taken into the cell to maintain stability. Eventually under very hypotonic conditions the cell ...
Pathology
null
999fae05-0f74-4b1a-b0c2-4144fd410e04
A three year old child is brought to the emergency depament having just ingested a large overdose of an antihistaminic drug. This drug is a weak base capable of entering most tissues including the brain. On physical examination the hea rate is 100/ minute, blood pressure is 110/60 mm Hg and the respiratory rate is 20/ ...
Urinary excretion would be accelerated by administration of NH4Cl, an acidifying agent
Urinary excretion would be accelerated by administration of NaHCO 3, an alkalinizing agent
More of the drug would be ionized at blood pH than at stomach pH
Absorption of the drug would be faster from the stomach than from the small intestine.
0a
multi
This question can be solved by the knowledge that basic drugs are ionized in the acidic medium and vice-a-versa. This antihistaminic drug is a weak base and will be highly ionized in the acidic urine. As ionized drugs cannot be reabsorbed in the nephron, urinary acidifying agents like NH4Cl will accelerate the excretio...
Pharmacology
Histamine, 5-HT and PGs
138ae62a-1c8a-44f0-a3d1-631677c36758
A patient on t/t for psychiatric disorder takes overdose of a drug, develops bradycardia, hypotension, decreased sweating and salivation. The likely drug is
Amitryptilline
Lithium
Selegiline
Amphetamine
0a
single
A i.e. Amitryptilline
Psychiatry
null
d300a83c-e9e0-43ef-a36a-46436846acf9
Which of the following is an absolute indication for surgery in cases of benign prostatic hyperplasia -
Bilateral hydroureteronephrosis
Nocturnal frequency
Recurrent urinary tract infection
Voiding bladder pressures > 50 cm of water
2c
single
Absolute indications for surgical treatment of BPH 1) Refractory urine retention (failing at least one attempt at catheter removal 2) Recurrent UTI from BPH 3) Bladder stones d/t BPH 4) Renal insufficiency d/t BPH 5) Large bladder diveicula secondary to BPH 6) Recurrent gross hematuria from BPH Ref : Cambell's Urology ...
Anatomy
Urology
ec52d55a-71e0-420b-b01e-410856e4742a
Phenylketonuria caused by deficiency of
Tyrosine transaminase
Tyrosine hydroxylase
Phenylalanine hydroxylase
Phenylketonuria hydroxylase
2c
single
(C) Phenyalanine hydroxylase # Phenylketonuria is a genetic disorder inherited from a person's parents.> It is due to mutations in the PAH gene which results in low levels of the enzyme phenylalanine hydroxylase.> This results in the build up of dietary phenylalanine to potentially toxic levels. It is autosomal recessi...
Biochemistry
Miscellaneous (Bio-Chemistry)
ebb284f7-11a1-4ebe-8bd5-bdfa937b699e
Telefono is:
Pulling of hair
Beating on soles
Beating on ears
Beating on fingers
2c
single
Simultaneous beating of both ears with the palms of the hands is known as TELEFONO. This may lead to rupture of the tympanic membrane causing pain, bleeding and hearing loss. It is difficult to detect this. The external ear may also get torn during pulling of the ears.
Surgery
null
d7563a70-1643-4e4c-88cf-e7dd93c66c08
All of the following are direct causes of maternal moality except:
APH
PPH
Hea disease
Eclampsia
2c
multi
Ans. is c i.e. Hea disease
Gynaecology & Obstetrics
null
56d44622-0c1f-44d3-b0c9-18b746e8fd67
who introduced ECT
manfred bleuler
moerin seligman
lucio bini
freud
2c
single
HISTORY * Medunna ====IM injection of camphor to induce seizures * Ugo cerletti and lucio bini==== ECT in a catatonic patient INDICATIONS * DEPRESSION SUICIDAL IDEAS-------------- first choice * CATATONIC SCHIZOPHRENIA * SCHIZOPHRENIA * MANIA * ELECTRODE PLACEMENT * Most commonly used=== bi fronto temporal * More cogni...
Anatomy
Treatment in psychiatry
001ebeb7-4f6d-4dfd-9506-6c37052effed
MELD score includes all except
S. bilirubin
S. creatinine
Prothrombin time
Serum albumin
3d
multi
Serum albumin is not a part of MELD SCORE. It is a part of child - pugh classification.
Medicine
null
e08a9e46-4ec3-4804-89f2-62076624b4a1
All of the following are carcinogenic except
H. pylori
Hepatitis B virus
E.B. virus
Campylobacter
3d
multi
null
Medicine
null
a2bd8ecf-4d4f-4b70-8555-0016e509cea9
All are hypercoagulable states, except ?
Protein C resistance
Protein S deficiency
Antiphospholipid antibody
None
3d
multi
Ans. is 'None' o All are hypercoagulable states.
Pathology
null
fc3752dc-4cd4-45ad-97c8-be70935dd190
Which of the following is the most common cause of meningoencephalitis in children:
Mumps
Arbovirus
HSV
Enterovirus
3d
single
Answer is D (Enterovirus): Enteroviruses are the most common cause of viral meningoencephalitis. Arboviruses, HSV and Mumps virus are all impoant agents associated with viral meningoencephalitis, but Enteroviruses are the most commonly associated agents and the answer of choice. 'Enteroviruses are the most common cause...
Medicine
null
a12d492c-4bbf-4b65-bd36-7edd33a2a31b
Use of this instrument during examination of the ear provides all except
Magnification
In suctioning of middle ear secretions
Assessing Tympanic Membrane Movement
Removal of Foreign body
3d
multi
null
ENT
null
c1ec1131-bc33-4f11-982a-195c67965f10
Pneumocystic carnii infects:
Human
Monkey
Rat
Cats
2c
single
Ans. c. Rat
Microbiology
null
160a9e24-b343-4294-9325-2d669c4991b6
All of the following are true about Roll back malaria except:(AIIMS November 2013, Nov 2012)
Insecticide treated mosquito nets
Strengthening health system
Development of newer insecticide
Training of health workers
2c
multi
Ans. c. Development of newer insecticide (Ref; Harrison 19/e p14,18/e p14 WHO Roll Back Malaria Document] HTM_ MAL 2005. 1101.pdf (Roll Back Malaria)Roll Back Malaria:Messages on malaria case management, intermittent preventive treatment during pregnancy and insecticide- treated netsQ (ITNs) were promoted using volunte...
Social & Preventive Medicine
Communicable Diseases
123a9645-cd27-40cc-a75d-3327f13b2094
All are associated with EBV except -
Infectious mononucleosis
Nasopharyngeal carcinoma
Oral hairy leukoplakia
Epidermodysplasi
3d
multi
EBV causes nadopharyngeal carcinoma,oral hairy luekoplakia&infectious mononucleosis REF:MICROBIOLOGY ANANTHA NARAYANAN NINTH EDITION PAGE.475
Microbiology
Virology
bffb48d4-541f-4f77-91ac-ecc7054fae36
Single most sensitive tool for evaluating the iron status is
Haemoglobin concentration
Serum ion concentration
Serum ferritin
Serum transferrin saturation
2c
single
Serum ferritin is the single most sensitive tool for evaluating the iron status.It reflects the size of Iron stores in the body. Values below 10 mcg/L indicate an absence of stored iron.Park 23e pg: 623
Social & Preventive Medicine
Nutrition and health
01fd7d4a-cb59-4712-ac88-cecf75b5357a
Chandu 32 years male presents with abdominal pain and vomitting. He also complain of some psychiatric symptoms & visual hallucination. Most likely diagnosis is
Hypothyroidism
Hypehyroidism
Hysteria
Intermittent Porphyria
3d
multi
D i.e. Intermittent porphyria
Skin
null
d15f2c4a-692f-4748-9828-37f062ef7ea7
In ARDS, all are seen except :
Dilated bronchioles
Edema
Fibrosis
Alveolar damage
0a
multi
Acute respiratory distress syndrome Aetiology and pathogenesis Acute respiratory distress syndrome (ARDS) is a diffuse neutrophilic alveolitis caused by a range of conditions and characterised by bilateral radiographic infiltrates and hypoxaemia. Activated neutrophils are sequestered into the lungs and capillary permeab...
Medicine
null
403b25ad-84aa-42f2-83d6-755b2b29cbe8
Population covered by a PHC in hilly region is –
20000
30000
40000
25000
0a
single
One PHC for every 30,000 rural population in the plains. One PHC for every 20,000 population in hilly, tribal and backward areas.
Social & Preventive Medicine
null
a60b17ba-44e5-4ecb-a214-6b635eba4456
Which of the following factor determines the destructive power of bullet after firing?
Weight of bullet
Shape of bullet
Size of bullet
Velocity of bullet
3d
single
A bullet's ability to injure is directly related to its kinetic energy at the moment of impact. Kinetic energy i.e. E = mv2 /2 The kinetic energy is directly propoional to weight (mass) of the bullet and the square of its velocity. Thus a bullet traveling at twice the speed of a second bullet of equal weight and simila...
Forensic Medicine
null
62823f3f-7982-41f7-9ed8-127c8c46ca54
Baroreceptor stimulation producesa) Decreased heart rate & BPb) Increased heart rate & BPc) Increased cardiac contractilityd) Decreased cardiac contractility
b
c
ac
ad
3d
single
Baroreceptors are present in carotid sinus and aortic arch. Increase in BP activates them which results in decrease in the sympathetic discharge. This leads to decrease in cardiac contraction, heart rate and BP.
Physiology
null
efa549f6-69f0-48e0-aef2-d0d83c877881
Which of the following anti–cancer drug is NOT 'S'–phase specific ?
Methotrexate
Mercaptopurine
Ifosfamide
Thioguanine
2c
single
null
Pharmacology
null
feb06a8e-a492-4e40-9f36-99d4ad9c184b
Dose of vitamin A prophytaxis given in age group 16 years -
2000 iu
20000 iu
200000 iu
100000 iu
2c
single
Ans. is 'c' i.e., 200000 iu
Social & Preventive Medicine
null
0c8a6c4a-472c-419d-8e18-33ffaa51f158
The principle that is the spinal cord dorsal roots are sensory and the ventral roots are motor is known as -
Laplace's law
Bell-Magendle's law
Frank-Starling's law
Weber-Fechner's law
1b
single
(B) (Bell Magendie law's) (157 - Ganang 23rd)* Bell Magandie law - In the spinal cord dorsal roots are sensory and ventral roots are motors (DS - VM)* Weber Fachner law - Magnitude of sensation felt in proportionate to the log of intensity of the stimulus**.* Law of pro jection states than no matter where a particular ...
Physiology
Nervous System
5f75a419-705c-4711-8c8f-b5cdb3939ae4
Bullet that leaves a visible mark in its flight so that person can see the path is
Tandem bullet
Tracer bullet
Dum-dum bullet
Incendiary bullet
1b
single
Tracer bullet: It leaves a visible mark or 'trace' while in flight, so that the path of bullet can be seen . Dum - dum bullet: The nose of the bullet is not covered by jacket & exposed. It expands or mushrooms on striking the target, producing a large hole & more damage. Incendiary bullets: Incendiary bullets contain p...
Forensic Medicine
Ballistics
e376038e-51b1-4801-b7c0-e17b9b0b35cb
Of the following which does not categorise under Rape? Sexual intercourse with :
Wife below 15 years
Wife above 15 years
Women below 16 years
Women above 20 years
3d
multi
B i.e. Wife above 20
Forensic Medicine
null
be89e67d-ffdb-4c6a-95b3-76801c3ced29
Congenital rubella syndrome - true is A/E?
Microcephaly
VSD
Conduction defect
All
2c
multi
Ans. is 'c' i.e., Conduction defect
Pediatrics
null
a630369e-b468-4a49-9ae8-ae098e782d41
Anaesthetic agent with vasoconstrictor is contraindicated in ?
Digital block
Spinal block
Epidural block
Regional anaesthesia
0a
single
null
Pharmacology
null
4e5094da-d5bd-4233-b972-73d37ca5b373
Mesencephalo-oculo-facial-angiomatosis is seen in:
KTW Syndrome
NF-1 & 2
Sturge-Weber syndrome
Wyburn-Mason syndrome
3d
single
D i.e. Wyburn-Mason syndrome - Wyburn-Mason syndrome (or Bonnet-Dechaume Blanc syndrome mesencephalo-oculo-facial or mesencephalo-optico retinal angiomatosis syndrome) is characterized by neuro (mesencephalo) - optico / oculo / retinal - facial angiomatosis (vascular-malformations). - Wyburn-Mason syndrome presents wit...
Radiology
null
0d6da8ac-e8bb-455d-87ef-bfe6551d408d
The following drug has anxiolytic action with least sedation
Buspirone
Triazolam
Alprazolam
Chlordiazepoxide
0a
single
Features of Buspirone Non-benzodiazepine anxiolytic agentDoes not produce significant sedation or cognitive/functional impairmentDoes not interact with BZD receptor or modify GABAergic transmissionDoes not produce tolerance or physical dependence Does not suppress BZD or barbiturate withdrawal syndrome Has no muscle re...
Pathology
All India exam
da0a872c-8665-415f-86c3-57866c26ebae
Age of gestation when ovaries and testis are first distinguishable :
4 weeks
8 weeks
12 weeks
16 weeks
1b
single
8 weeks
Gynaecology & Obstetrics
null
36503675-efa0-46dc-976b-d41c2c6493d4
The testis descends the inguinal canal during...month.
5th
6th
7th
8th
2c
single
C i.e. 7th
Anatomy
null
53a8828b-8190-441f-8114-4204bfc98680
Index measuring deprivation in basic dimensions of human development
Human povey index
Human development index
Physical quality of life index
Development deprivation index
0a
single
The Human Povey Index (HPI) was considered to better reflect the extent of deprivation to the HDI. In 2010 it was supplanted by the UN&;s Multidimensional Povey Index.
Social & Preventive Medicine
Concept of health and disease
ad30ea48-320f-4d5f-913c-a981cd6b3218
Cells occurring in greatest number in pulp are
Cementoblasts
Fibroblasts
Osteoblasts
Ameloblasts
1b
single
null
Dental
null
0e8df3b1-79ed-466c-a60f-8a04a8d13276
Keratocyst has all of the following features except:
It is more common in mandible
May be filled with thin straw coloured fluid
Low recurrence rate
Expansion of bone clinically seen
2c
multi
null
Pathology
null
039cc18f-f538-49d4-bd6a-a8e7028cf7a7
A child with vesicoureteric reflex of grade 2 comes to OPD. What is the preferred treatment method
Antibiotics
Observation
Sting operation
Ureteric reimplantation
0a
single
Prophalyctatic antibiotics is given to all vesicoureteric reflex pts.
Surgery
null
433065e4-222d-4579-bbeb-fc4bd63b011b
A 60 yr old person presents with a mass located at central bronchus causing distal bronchiectasis and recurrent pneumonia. Which of the following findings is expected from biopsy of the mass?
Abundant osteoid matrix formation
Contains all three germ layers
Spindle cells with abundant stromal matrix
Small round cells and hyperchromatic nuclei with nuclear moulding
3d
multi
Ans. (d) Small round cells and hyperchromatic nuclei with nuclear moulding(Ref: Robbins 9th/pg 715-717)This typical presentation of 60 yr/M presenting with a mass located at central bronchus causing distal bronchiectasis and recurrent pneumonia is suggestive of small cell Carcinoma.In Small cell Ca lung, location in lu...
Pathology
Respiration
1abd9ca7-7e2d-4c0e-9232-2324a9d45711
patient has decreased weight, need for thinness, the diagnosis is
refeeding syndrome
anorexia nervosa
metabolic syndrome
bulimia nervosa
1b
single
Anorexia nervosa Anorexia nervosa is a eating disorder where the patient has decreased weight and altered body image and persistent desire to maintain thinness * Gender==== more common in females * Age=======adolescence * Comorbidity=== depression and social phobia * Duration====3 months * Criteria= * Intense fear of b...
Anatomy
Sleep disorders and eating disorders
5534724a-f7b5-45d8-9482-d70b0494bee8
All cause viral hepatitis except -
Measles
EBV
Rhinovirus
Reovirus
2c
multi
Ans. is 'c' i.e., Rhinovirus Impoant viruses causing hepatitis:? 1) Hepatotropic viruses : HAV, HBV, HCV, HD V, HEV. 2) Herpes viruses : CMV, EBV, HSV-1, VZV. 3) Flaviviruses : Yellow fever, dengue fever. 4) Filoviruses : Marburg virus, Ebola virus. 5) Occasinal causes Measles virus, adenovirus, Echoviruses, Coxsackiev...
Microbiology
null
eb262283-bb00-410c-83a7-f84b3e5b63fc
Krukenberg tumor is associated mostly with which cancer?
Stomach
Breast
Liver
Pancreas
0a
single
Krukenberg tumor is a distinctive bilateral tumor metastatic to the ovaries by the transcoelomic spread. The tumor is generally secondary to a gastric carcinoma but other primary sites where mucinous carcinomas occur (e.g. colon, appendix, and breast) may also produce Krukenberg tumor in the ovary. Rarely, a tumor havi...
Pathology
miscellaneous
4751c263-2c20-4643-99d2-fca4aa0228e0
All of the following are true about Nizatidine except
It is a H2 blocker used in peptic ulcer disease
It has 100% Bioavailability
It also enhances gastric emptying
It can also lead to tachycardia
3d
multi
Nizatidine is a H2 blocker with anticholinesterase activity, thus enhances gastric emptying and can also cause bradycardia.
Pharmacology
null
4795500f-50f9-415f-bf6d-70a71662f3ce
The Halstead Retain battery involves all except :
Finger oscillation
Constructional praxis
Rhythm
Actual performance
1b
multi
In Halstead - Reitan battery test, the battery is composed of ten tests : Category test. Tactual performance test. Rhythm test. Finger - oscillation test. Speech-sound perception test. Trail - making test. Critical flicker frequency. Time sense test. Aphasia screening test. Sensory - perceptual test.
Psychiatry
null
ec6e9f6e-c32b-4dca-98a9-b4cbb2ad8444
After mandibulectomy, muscle preventing falling back of tongue -
Genioglossus
Hyoglossus
Palatopharyngeus
All of the above
1b
multi
null
ENT
null
38cbe847-e841-4587-a655-9b183830f26c
Which of the following is NOT TRUE about post - traumatic stress disorder?
The onset of illness may occur many months after the traumatic event
Individual debriefing and early counselling are most effective method of treatment
Eye movement desensitization and reprocessing is effective
There is high risk of alcohol abuse in patients suffering from this disorder
1b
multi
Treatment of choice for PTSD is psychotherapy in the form of cognitive behavior therapy often in combination with pharmacotherapy. There is no evidence that single - session individual psychological briefing is a useful treatment for PTSD. Eye movement desensitization and reprocessing (EMDR) is an effective treatment f...
Psychiatry
null
6c292dc0-d36d-4441-b64d-03f8bd4237eb
Which of the following malignancy shows least lymph node involvement:
Supraglottic
Subglottic
Glottic cancer
Ca nasopharynx
2c
single
Ans: c (Glottic cancer) Ref: Dhingra, 3rd ed, p. 372; 4th ed, p. 286No lymphatics in vocal cords so nodal metastasis are practically never seen in cord lesions unless the disease spreads beyond the membraneous cord. SupraglottisGlottisSubglottisSiteEpiglottisAryepiglottic foldArytenoidVentricular bandsVentricles & sacc...
ENT
Tomour of Larynx
71dae00e-552e-4285-949c-da8b352ba804
Complex polysaccharides are converted to glucose and absorbed by the help of:
Na+k+ATPase
Sucrase
Enterokinase
Carboxypeptidase
1b
single
Ans: b (Sucrase) Ref: Vasudevan, 4th ed, p.Sucrase or invert sugar converts sucrose (which is a complex polysaccharide) into 1 molecule of glucose and 1 molecule of fructose.Na+k+ ATPase is a membrane protein.Enterokinase is a brush border enzyme in intestinal mucosa which will activate trypsinogen to trypsin.Proteolyt...
Biochemistry
Carbohydrates
c89f3315-db72-42aa-8bfb-835c9fe59d3c
The most prominent toxic effect associated with acetaminophen use is
Respiratory alkalosis
Haemorrhage
Hepatic necrosis
Gastric Ulceration
2c
single
null
Pharmacology
null
94a3ee08-9f21-42c0-81ce-6168af594e82
A 47-year-old woman is admitted to the hospital with signs of cavernous sinus thrombosis. Radiographic examination reveals a pituitary tumor involving the cavernous sinus, confirming the initial diagnosis. During physical examination it is suspected that the right abducens nerve of the patient has been damaged by the t...
Inward
Outward
Downward
Down and out
1b
single
(b) Source: GAS 849-852, 855; GA 450, 465, 536The right abducens nerve innervates the right lateral rectus, which mediates outward movement (abduction) of the right eye. Inward movement is accomplished by the medial rectus, supplied by the oculomotor nerve. Downward movement in the midline is accomplished by joint acti...
Anatomy
Head & Neck
9761b4e0-5a31-447d-8c63-3e524a1bc862
False about osteoahritis is ?
Involves synol joints
Progressive softening of the aicular cailage
It is an inflammatory ahritis
Marginal osteophytes are produced
2c
multi
Ans. is 'c' i.e., It is an inflammatory ahritis Osteoahritis (OA) is a chronic disorder of synol joints in which there is progressive softening and disintegration of aicular cailage accompanied by new growth of cailage and bone at the joint margins (osteophytes), cyst formation and sclerosis in the subchondral bone, mi...
Surgery
null
189ac40f-d3d2-4755-a82d-e7f870011105
Orange-skin cornea results due to:
Chalcosis
Siderosis
Ammonia burn
Mustard gas
3d
single
Ans. Mustard gas
Ophthalmology
null
994df741-8822-49b0-8ccc-c12e023d5fc2
Fracture of the hyoid bone results from all except :
Throttling
Hanging
Choking
Ligature strangulation
2c
multi
C i.e. Choking - Burking is a method of homicidal smothering and traumatic asphyxiaQ. In smothering lips, gums, tongue, inner side of mouth & nose may show bruising or lacerationQ. Asphyxial signs (eg congestion, cynosis & patechiae) are severe except when the head & face is enclosed in plastic bag. In smothering, chok...
Forensic Medicine
null
a85d45e7-06f2-478f-a861-e3693b6e7ab7
Accordian sign is seen in
Pseudomembranous colitis
Intussusception
Ileocecal TB
Ischemic colitis
0a
single
The 'Accordion sign' (also known as 'conceina sign') is seen on CT examinations of the abdomen Refers to the similarity between the thickened oedematous wall of Pseudomembranous colitis and the folds of an accordion. This appearance is the result of hyperaemic enhancing mucosa stretched over markedly thickened submucos...
Radiology
Gastrointestinal Radiology
a7bfb539-b5aa-44b9-9b87-76f1b576ad95
Melting temperature of DNA is directly proportional to
GC Pairing
AT Pairing
Length of DNA
None of the above
0a
multi
GC pairs have 3 hydrogen bonds and therefore melt at higher temperature compared to AT pairs which have 2 hydrogen bonds.
Biochemistry
null
399d5486-c9a4-47fa-893c-ecd209131b43
Which is the latest antiviral drug for bronchitis due to RSV-
Ribavarin
Acyclovir
Amantadine
Idoxuridine
0a
single
null
Medicine
null
5a1688a3-71c6-490f-8621-64aa6d49ab7e
Phase 2 of Damage control surgery occurs at
Pre hospital management
Resuscitation in ICU
Resuscitation in operating room
Definitive repair
1b
single
Deadly triad of trauma Following a trauma protracted surgery in physiologically unstable patient, the three factors that carry moality are Hypothermia Acidosis Coagulopathy Hence originated a phenomenon - DAMAGE CONTROL SURGERY Phases of damage control surgery Phase1 :Initial exploration Phase 2: Secondary Resucitation...
Anatomy
General anatomy
6949bf17-a963-43f3-9a45-372daf211458
Romana's sign is seen in -
Toxoplasma
Trypanosoma cruzi
Loaloa
Wuchereria
1b
single
Ans. is 'b' i.e., Trypanosoma cruzi Romana's signo The classic finding in acute Chagas disease, which consists of unilateral painless edema of the palpebrae and periocular tissues - can result when the conjunctiva is the portal of entry.o These initial local signs may be follwed by malaise, fever, anorexia, and edema o...
Medicine
Parasitology
d5d5ce9d-4269-421c-98ef-075b104cfb81
30 Yr old man which is most likely organism causing infection of epididymis -
E.coli
Gonococci
Chlamydia
Ureaplasma ureolyticum
2c
single
null
Medicine
null
2f39ca11-d54f-459e-aee2-7ad761bdc720
An elderly diabetic with excruciating pain in ear, appearance of granulation in meatus, skull base infection with facial paralysis should be treated with
Penicillin
Ciprofloxacin
2nd generation ciphalosporin
Erythromycin
0a
single
All clinical features are suggestive of malignant otitis externa, an inflammatory condition of the external ear. Malignant otitis externa (also k/a Necrotizing external otitis) Malignant otitis externa is an inflammatory condition of the external ear usually spreading deep to cause osteomyelitis of temporal bone and ba...
ENT
null
4d79b9ad-7f79-411a-8ea8-917c369d3307
Meniere's disease is characterized by all except -
Conductive deafness
Sensorineural deafness
Vertigo
Tinnitus
0a
multi
null
ENT
null
99556d84-5417-4ac7-8975-f746b36805a5
Digoxin toxicity may result from the concurrent administration of digoxin with all of the following drugs EXCEPT
Quinidine
Hydrochlorothiazide
Triamterene
Furosemide
2c
multi
Triamterene is a potassium-sparing diuretic that may protect against diuretic-induced digoxin toxicity. Digoxin toxicity may be caused by drugs that increase serum digoxin levels or increase the binding of digoxin to its receptor, the sodium-potassium adenosine tn phosphatase (ATPase). Quinidine decreases digoxin volum...
Unknown
null
d0efa4a0-aeef-4af5-acef-c41cfb68529e
Which of the following drugs is contraindicated along with spironolactone
Chlorothiazide
Beta blockers
ACE inhibitors
Amlodipine
2c
single
CONTRAINDICATIONS / PRECAUTIONS Adrenal insufficiency, anuria, diabetes mellitus, hyperkalemia, renal disease, renal failure, renal impairment. ... Acid/base imbalance, metabolic acidosis, metabolic alkalosis, respiratory acidosis. ... Ascites, biliary cirrhosis, hepatic disease. ... Menstrual irregularity.
Pharmacology
Kidney
4992644f-8c52-437d-8c4e-4936560776ac
A 3-year-old male has come for a routine dental check up. Intra-oral examination reveals good oral hygiene and open proximal contacts. During previous dental appointments, he was cooperative. Which radiographic assessment should be done for this patient?
No radiographic assessment.
Bitewing Radiographs
Intraoral periapical radiograph
Occlusal radiographs
0a
single
The American Dental Association (ADA), the American Academy for Pediatric Dentistry (AAPD), the European Academy for Pediatric Dentistry (EAPD), and other organizations have published criteria that are meant to guide the dental professional in decision-making regarding appropriate radiographic imaging (Table 2-5). Thes...
Dental
null
731a8ecd-16ed-402f-8578-141b340b999b
First to recover from post-operative ileus:
Small intestine
Stomach
Colon
None
0a
multi
POST-OPERATIVE ILEUS - Following most abdominal operations or injuries, the motility of GI tract is transiently impaired. - Proposed mechanisms responsible for this dysmotility are surgical stress-induced sympathetic reflexes, inflammatory response mediator release, and anesthetic / analgesic effects; each of which can...
Surgery
Intestinal obstruction
08df94e4-52f1-4767-9a91-61804a3d5211
Watershed zone of large intestine ?
Cecum
Ascending colon
Rectosigmoid
Transverse colon
2c
single
There are areas of colon with poor blood supply resulting from incomplete anastomosis of marginal aeries. These are watershed areas of colon and include :Splenic flexure (Griffith point) : Watershed area between superior mesenteric aery and inferior mesenteric aery.Rectosigmoid junction (Sudeck's point) : Watershed zon...
Anatomy
null
9acb545d-1542-40e7-9f10-994e185d6d14
Which one of the following is a relatively selective α2 adrenergic blocker with short duration of action ?
Prazosin
Yohimbine
Terazosin
Doxazosin
1b
single
null
Pharmacology
null
14e26f14-0537-4bc3-b0f8-453efa471ef8
Oxidative deamination is catalyzed by ?
Glutaminase
Glutamine synthase
Glutamate dehydrogenase
None of the above
2c
multi
Ans. is 'c' i.e., Glutamate dehydrogenase
Biochemistry
null
75541196-9764-4d4c-afa5-c3276ee877e1
Which of the following is indicated by the term 'mittelschmerz'?
Fern pattern of cervical mucus
Peritoneal irritation from corpus hemorrhagicum
Rise of body temperature due to effect of progesterone
LH surge before ovulation
1b
single
The follicle that ruptures at the time of ovulation promptly fills with blood, forming what is sometimes called a corpus hemorrhagicum. Minor bleeding from the follicle into the abdominal cavity may cause peritoneal irritation and fleeting lower abdominal pain ("mittelschmerz"). The granulosa and theca cells of the fol...
Gynaecology & Obstetrics
null
c58edc55-a598-4caf-85a8-58adf462458b
Best prognostic indicator for head injured patients: AIIMS 10
GCS
CT findings
Age of the patient
History
0a
single
Ans. GCS
Forensic Medicine
null
32a5bb96-4239-45a9-a95e-e8baf8a88888
All the following are cyanotic hea disease except
TOF
PDA
Tricuspid atresia
Eisenmenger's complex
1b
multi
Ref Harrison 19 th ed pg 1523 Patent ductus aeriosus is not classified as a cyanotic congenital heayh disease. PDA is an acyanotic hea disease with left to right shunt.
Anatomy
General anatomy
68f2ba99-cf08-4694-83af-d803b257d5f0
Aicular cailage is made up of-
Type I collagen
Type II collagen
Type III collagen
Type IV collagen
1b
single
Ans. is `b' i.e., Type H Collegen type Tissue distributionUbiquitous in hard & soft tissuesII & IX Cailage, interveebral disc, vitreousIn Hollow organs & soft tissuesIV Basement membraneV Blood vesselsVI Ubiquitous in microfibrilsVII Dermoepidemal junctionIX Cailage & VitrousNote : Amongst these type I, II, III, V & IX...
Pathology
null
8d7ab965-4d7f-4dc9-a4b4-44bbc7334175
Mechanism of action of the sulfonylureas is
K+ ATP channel blocker
Na ATP channel blocker
Cl ATP channel blocker
Ca ATP channel blocker.
0a
single
Ans. is 'a' i.e., K ATP channel blocker * Sulfonylurease provoke a brisk release of insulin from pancreas. They act on the so called "Sulfonylurea receptors" (SUR1) on pancreatic b-cell membrane - cause depolarization by reducing conductance of ATP sensitive K+ channels. This enhances influx of Ca+2 - degranulation. Th...
Pharmacology
Endocrinology
2b862666-986e-481c-b468-fd7f5e1b891c
Lower lobe fibrosis is seen in :
Silicosis
Sarcoidosis
Cystic Fibrosis
Asbestosis
3d
single
Answer is D (Asbestosis): Lower lobe fibrosis is seen in Asbestosis. Silicosis, Sarcoidosis and Cystic Fibrosis are all associated with Upper Lobe Fibrosis Upper Lobe Fibrosis Fibrotic Disease Old Granulomatous Infection (Tuberculosis; Histoplasmosis; Coccidioidomycosis) Sarcoidosis Silicosis, Berylliosis Coal Worker's...
Medicine
null
31ae8a7a-6ec6-4519-b954-0e6673614e9e
Which ocular muscle does NOT arises from apex of orbit
Superior rectus
Inferior rectus
Superior oblique
Inferior oblique
3d
single
D. i.e. Inferior oblique
Anatomy
null
1d470f6d-670d-4819-b765-07398e613da3
The cuspal inclines of the maxillary buccal cusps and the mandibular lingual cusps should be grounded if they are in deflective occlusal contact in:
Working position only
Balancing position only
Both working and balancing positions
Central position
0a
multi
null
Dental
null