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135
12bad48b-d4a5-48ce-b673-154d499aeec3
Duret hemorrhages are seen in -
Forebrain
Occipital lobe
Pons
Temporal lobe
2c
single
Ans. is 'c' i.e., Pons Duret Hemorrhage:* It is the hemorrhage of mid brain and pons secondary to herniation of brain.* This lesion in most cases is a secondary midline hemorrhage resulting from rapid assymetrical herniation of brainstem downwards.* The midline lesion usually involves the mid brain and pons but never t...
Surgery
Nervous System
b4aaa225-bb90-4059-990e-3148ab94c600
Ball's operation is done for :
Ca. Cx
Ca. Ovary
Ca. Fallopian tube
Pruritus vulvae
3d
multi
Pruritus vulvae
Gynaecology & Obstetrics
null
29c58f40-7986-4f78-b56f-525ac45a0190
High inguinal orchidectomy specimen showed tumor testis with involvement of epididymis without vascular invasion; Stage is -
T 1
T 2
T 3
T 4
0a
single
null
Surgery
null
e17d2a44-b352-4677-a08f-7f1a793cd028
Emergency or reemergence seen in which of the following organisms -a) Polio virusb) Measles virusc) Nipah virusd) West Nile viruse) Hepatitis B virus
abd
cde
bde
ade
1b
single
null
Social & Preventive Medicine
null
3fa1c5dd-1b4d-446c-b71e-abe00cfd12f7
All the following are components of APGAR Score EXCEPT:
Muscle tone
Color of the body
Heart Rate
Respiratory Rate
3d
multi
ANSWER: (D) Respiratory RateREF: William's Obstetric 22nd edition chapter 28 Table 28-2, http://en.wikipedia.org/wiki/Apgar_ score"Respiratory effort not rate is a part of Apgar scoring system"APGAR SCORE:A useful clinical tool to identify those neonates who require resuscitation as well as to assess the effectiveness ...
Pediatrics
Newborn Infant - Physical Examination
06224568-f53f-4544-9b5c-e1900d9c929f
A 24-year-old woman is dipstick positive for blood in her urine. This is repeated twice between menstrual periods and remains positive. Microscopic evaluation reveals RBCs, some of which are deformed and some in the form of casts. Which of the following is the most likely cause of the hematuria?
urinary tract stones
GN
trauma
benign renal tumor
1b
single
Isolated hematuria is usually of urologic cause (e.g., tumor, trauma, stone) but can also be glomerular in origin. The finding of red cell casts or dysmorphic red cells (best appreciated by phase microscopy) suggests the source of bleeding is glomerular in origin.
Medicine
Kidney
ae254508-7437-4d30-b730-c674e82cabdc
Most common site of minor salivary gland tumor
Cheek
Palate
Sub-lingual gland
Tongue
1b
single
null
Surgery
null
000eb060-5efe-4cd9-a28a-efccc43b2270
All of the following statement about neuromuscular blockage produced by succinylcholine are true except
No fade on Train of Four stimulation
Fade on tetanic stimulation
No post tetanic fecilitation
Train of four ratio 1
1b
multi
Depolarizing neuromuscular blocker The only drug still in clinical use belonging to this group is succinylchloline. Mode of action The effects of succinylcholine (SCh)at the neuromuscular junction are depolarizing postsynaptic and extrajunctional receptors, normally, this desensitization process does not occur with ace...
Anaesthesia
Neuromuscular Blocker
d002a289-0e0b-42e3-97aa-a454e892cad8
Number of teeth at 7 years:
20
24
26
28
1b
single
Ans. 24
Forensic Medicine
null
6a57cdcb-3d24-4ef8-bbd8-46f2007b8bfe
Asbestosis is associated with all except:
Central emphysema
Interstitial fibrosis
Pleural effusion
Carcinoma larynx
0a
multi
(A) Central emphysema# Asbestosis and Asbestos-Related Diseases> Asbestos is a family of crystalline hydrated silicates with a fibrous geometry.> On the basis of epidemiologic studies, occupational exposure to asbestos is linked to> Parenchymal interstitial fibrosis (asbestosis);> Localized fibrous plaques or, rarely, ...
Pathology
Misc.
e6ae3bab-b5c4-43d8-8092-f4180963f5eb
Which of the following is not a sign of advanced COPD?
Significant weight loss
Cor pulmonale
Hoover's sign
Clubbing
3d
single
Advanced disease may be accompanied by cachexia, with significant weight loss, bitemporal wasting, and diffuse loss of subcutaneous adipose tissue.Some patients with advanced disease have paradoxical inward movement of the rib cage with inspiration (Hoover's sign)Signs of ove right hea failure termed cor pulmonale migh...
Medicine
Respiratory system
74170d9e-5159-464c-91cb-9f34fc6fe393
Pathology of Alzeheimer's disease is:
Deficiency of cholinergic action
Excess action of dopamine
Accumulation of beta-amyloid protein
None of the above
2c
multi
Ans. C: Accumulation of beta-amyloid protein Alzheimer's disease (AD) is a slowly progressive disease of the brain that is characterized by impairment of memory and eventually by disturbances in reasoning, planning, language, and perception. Many scientists believe that Alzheimer's disease results from an increase in t...
Pathology
null
7c3e753d-624e-456f-a9f1-deee118d4601
A 40 -- years -- old woman presented to the gynecologist with complaints of profuse vaginal discharge. There was no discharge from the cervix on the speculum examination. The diagnosis of bacterial vaginosis was made based upon all of the following findings on microscopy except :
Abundance of gram variable coccobacilli
Absence of Lactobacilli
Abundance of polymorphs
Present of clue cells
2c
multi
Ans. is c i.e. Abundance of polymorphs In Bacterial vaginosis, polymorphs are either absent or there is only a slight increase.
Gynaecology & Obstetrics
null
3c4746c7-5717-4a25-b856-13bad9e16424
The distance between implant and adjustment tooth should be at least
7 mm
1.5 mm
3.5 mm
3.75 mm
1b
single
null
Dental
null
e0dc872d-7691-454f-87fd-95bfb96035f4
Drug transpo process that requires energy
Active transpo
Passive diffusion
Conventive current
Pinocytosis
0a
single
The passage of substances against their electrical and chemical gradient at the expenditure of energy is called active transpo. (REF: TEXTBOOK OF MEDICAL PHYSIOLOGY GEETHA N 2 EDITION, PAGE NO - 6)
Physiology
General physiology
008d57e7-5fcb-426d-a8b9-68c4efc0518c
The impoant light microscopical feature in Alpo syndrome are all, EXCEPT:
Interstitial fibrosis
Tubular hyperophy
Segmental proliferative
Glomerular changes
1b
multi
The light microscopic findings are not characteristic in alpo syndrome. It will be normal in early years of life. In older patients the changes seen are 1. Interstitial fibrosis, 2. Tubular atrophy, 3. Foam cells, 4. Segmental proliferative The presence of interstitial foam cells has been considered as suggestive of Al...
Medicine
null
e631f2f1-b75a-42d3-87a7-e5f72009979b
Which of the following has responsibility of data collection for active malaria surveillance at PHC level ?
DHO
MPW
MO-PHC
DMO
2c
single
Ans. is 'c' i.e., MO-PHC "The Medical Officer-PHC has the overall responsibility for surveillance and laboratory services, and also supervices the spray".
Social & Preventive Medicine
null
999a3d3c-24ce-4626-aa92-2d27c6c98ab5
Bacterial indicator for dry heat sterilization is ?
Bacillus subtilis
Bacillus pumilis
Bacillus stearothermophilus
Coxiella burnetti
0a
single
sterilization control Biological; the spore of a nontoxigenic strain of Clostridium tetani Bacillus subtilus subsp.niger are used microbiological test of dry heat efficacy REF:Ananthanarayan & Panicker's Textbook of Microbiology 9th edition pg no:30
Microbiology
general microbiology
1d903e27-d20f-43d8-abc9-ca9db0f40f4b
PA view of chest X-ray is given here. What is the diagnosis?
Right Pneumothorax with right tracheal shift
Right Pneumothorax with left tracheal shift
Left Pneumothorax with left tracheal shift
Left Pneumothorax with right tracheal shift
1b
single
Given image is showing absent bronchioalveolar markings of right lung with tracheal shift towards left side which is suggestive of right pneumothorax. Pneumothorax: presence of air or gas in pleural cavity Also remember, Deep sulcus sign on supine chest X-ray in expiration phase is a feature of pneumothorax.
Anaesthesia
FMGE 2019
a5617ed0-0a78-4a55-aa4a-93923775e8f7
The most common complication of lateral condylar fracture in children is:
Valgus deformity
Cubitus varus
Malunion
Hyperextension
0a
single
Ref: Apley's System of Orthopaedics and Fractures, 9th editionExplanation:LATERAL CONDYLAR FRACTURES IN CHILDRENMost commonly around 6 years of age.Most common distal humeral epiphyseal fracture.Milch classification: Two types of lateral condylar fractures.Milch Type IFracture extends medially from the metaphysis into ...
Orthopaedics
Humerus Fractures
6a166f7e-649d-45c2-bd8a-955bf46e2f1d
Drugs used for recurrent depressive episodes -a) Imipramineb) Carbamazepine c) Fluoxetined) Na valproate
a
bc
ac
b
2c
single
Amongst the given options, Imipramine and Fluoxetine are antidepressants. Carbamazepine and Valproate are used for prophylaxis of BPD (not for recurrent unipolar depression).
Psychiatry
null
cdc85055-220c-4d82-8ccd-84afbfdffe2c
CA - 125 levels are elevated in
Endometriosis
Adenomyosis
Both 2 & 3
None of the above
2c
multi
CA-125 levels is elevated in → Endometriosis → Adenomyosis → Pelvic infection → Leiomyoma Although it is a tumor marker.
Gynaecology & Obstetrics
null
fc15422e-82dd-4ff9-85bc-16e0e3df86b9
Pentameric structure ?
IgM
IgG
IgA
IgD
0a
single
Ans. is 'a' i.e., Ig M IgM is a pentameric immunoglobulin with five, four - peptide subunits. o The subunits are joined together by J chain. IgM IgM is the earliest immunoglobulin class to be synthesized by the fetus, begining at 20 weeks of age. As it is not transpoed across the placenta, the presence of IgM in the fe...
Microbiology
null
dfd25133-c8bf-4d18-b942-4808dbac2061
All of the following are risk factors for deep vein thrombosis (DVT) except -
Duration of surgery more than thirty minutes
Obesity
Age less than forty years
Use of the oestrogen-progesterone contraceptive pills
2c
multi
null
Surgery
null
e7b0643a-a2dc-45d9-8be6-b94bdfbef484
Bacterial Index deals with
Tuberculosis
Leprosy
Syphilis
Gonorrhea
1b
single
In leprosy, Bacterial Index is the only objective way of monitoring the benefit of treatment. 0 No bacilli in any of 100 oil immersion fields1+ 1-10 in 1002+ 1-10 in 103+ 1-10 in each field4+ 10-1005+ 100-10006+ more than 1000It is calculated for each site examined an average is taken.Park 23e pg: 314
Social & Preventive Medicine
Communicable diseases
e810923d-2b4d-45d6-a573-a068623a1bbe
A new bom presents with discharge of urine from the umbilicus for 3 days. Diagnosis is
Meckel's diverticulum
Mesenteric cysts
Urachal fistula
Omphalocele
2c
single
(Urachal fistula) (211,1289- B & L 24th) (776- Nelson 18th) (986-Baily 25th)A persistent urachus (Urachal cyst, sinus, patient urachus or diverticulum) is due to failure of closure of the allantoic duct and is associated with bladder outlet obstruction* Patency should be suspected if a clear, light, yellow urine- like ...
Surgery
Miscellaneous
7fa27c10-29c1-4840-b93a-191ec44a02a2
Patient with hemophilia A have bleeding disorder because of
Lack of platelet count
Lack of platelet adhesion
Lack of factor VIII a during activation of factor X in coagulation coscade
Release of thromboxane A2
2c
single
Hemophilia A X - linked disorder 90% cases - deficiency of factor 8 10% cases functional defect of factor 8 Factor VIII a complex is the most important activator of factor X required for conversion of prothrombin to thrombin.
Pathology
null
5373bc56-e806-4263-976a-2246065887db
A 49-year-old man comes to the physician because of a history of recurrent attacks of drowsiness, sweating, and palpitations. His blood glucose level during one of the episodes is 52 mg/dL. Recovery occurs in response to intravenous 10% dextrose C-peptide levels are below the normal range. Which of the following is th...
Factitious insulin use
Gastrinoma
Glucagonoma
Insulinoma
0a
single
null
Medicine
null
a45cfd85-debb-40d8-9d48-3d5d4d245944
Which one of the following is a conjugated vaccine :
Hepatitis B
Rubella
Hemophilius influenza
Pertussis
2c
single
HIB PRP vaccine (conjugate vaccine) is available for H. influenzae type b. Currently no vaccine is available for non typable strains.
Pediatrics
null
685b9b9a-0dad-4206-b9f9-eafecc41b237
MHCll positive cells are. Except
B cells
T cells
Macrophage
Platelet
1b
multi
Ref Robbins 7/e p203; 9/e p194 Ananthanaraya 7/e p130 T cells platelet and RBC MHC class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on professional antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial ce...
Anatomy
General anatomy
c8a574b6-9ee9-4ef1-b79b-9f0bfec0aac9
Lithium should be Stopped how many days before surgery
1 days
2 days
3 days
4 days
2c
single
Lithium should be stopped around 48-72 hrs before surgery.
Anaesthesia
Preoperative assessment and monitoring in anaesthesia
b8219267-f570-4d62-94c0-0a801aac7dd2
The commonest cause of visual loss in AIDS is which one of the following
Toxoplasmosis
Herpetic retinitis
CMV retinitis
HIV retinitis
2c
single
Ans. (c) CMV retinitisRef Kanski, p. 442; John Hopkins HIV guide p. 60CMV retinitis is the most commonQ opportunistic ocular infection amongst patients with AIDS and is the most common cause of Visual morbidityQ
Ophthalmology
Uveal Tract
b4893222-25d3-48d8-81c3-3f311d5ab38b
Which among the following is identified by Western blotting
DNA
RNA
Proteins
t-RNA
2c
single
The procedure to separate and detect DNA fragments, termed Southern blotting. The Nohern and Western blot transfer techniques are used to size and quantitate specific RNA and protein molecules, respectively. A fouh hybridization technique, the Southwestern blot, examines protein-DNA interactions. In this method, protei...
Biochemistry
null
d95652d3-ebeb-4655-8dfc-75af2adc3904
Internal thoracic artery is a branch of -
1st part of subclavian artery
2nd part of subclavian artery
3rd part of subclavian artery
Thyrocervical trunk
0a
single
Ans. is 'a' i.e., 1st part of subclavian artery Ref: BDC Vol III 5th/e p. 179]Branches of subclav ian artery :-o 1st Part - Vertebral artery, internal thoracic artery, thyrocervical trunk, and on left side costocervical trunk,o 2nd Part -On right side costocervical trunk,o 3rd Part - Dorsal scapular artery.
Anatomy
Blood Vessels of Thorax
af419dc1-4d4b-491d-90d1-80f37a1c6d62
All are used for treatment of morphine dependence except -
Methadone
Clonidine
Naltreoxone
Disulfiram
3d
multi
Ans. is 'd' i.e., Disulfiram Treatment of morphine or heroin poisoningo Treatment can be divided intoTreatment of toxicity (overdose)o Overdose is a medical emergency, and is treated with opioid antagonist to reverse the complications (respiratory depression) by antagonizing the action on opioid receptors. Intravenous ...
Psychiatry
Opioid-Related Disorders
2bfa673b-a003-4de5-b1c0-e06014b73a2c
Patient with hemophilia A have bleeding disorder because of:
Lack of platelet aggregation
Lack of reaction accelerator during activation of factor X in coagulation cascade
Neutralization of antithrombin III
Release of Thromboxane A2
1b
single
Hemophilia A - X- linked disorder -90% cases- deficiency of factor 8 -10% cases - functional defect of factor 8 -Intrinsic Pathway affected -Factor VIIIa complex is the most impoant activator of factor X required for conversion of prothrombin to thrombin. -In symptomatic cases there is a tendency toward easy bruising a...
Pathology
Bleeding disorder
b05aadae-930a-4d73-bac2-837a490add5d
Initial investigation for an amoebic liver abscess is September 2009
USG
Exploratory laparotomy
CT scan
Technetium-99 scan
0a
single
Ans. A: USG Ultrasonography is the preferable initial diagnostic test. It is rapid, inexpensive, and is only slightly less sensitive than CT scan (75-80% sensitivity vs 88-95% for CT scan). Ultrasonography simultaneously evaluates the gallbladder and avoids radiation exposure. As opposed to scanning with technetium-99m...
Radiology
null
85459806-2e75-4494-b01c-c5e813a91419
A patient present painful vesicles in ear, and tongue. He is also complaining of facial weakness and hearing loss. Dignosis is ?
Fungal infection
Chicken pox
Ramsay hunt syndrome
None
2c
multi
Ans. is 'c' i.e., Ramsay hunt syndrome Ramsay hunt syndrome It is lower motor neuron type official palsy due to Varicella (herpes) zoster. Pain is often a prominent feature and vesicles are seen in the ipsilateral ear, on the hard palate and/or on anterior two third of tongue. It may involve other cranial nerves-V, VII...
Skin
null
43baa8ea-f52a-4068-83f3-90c74d0476fe
5-nucleotidase activity is increased in
bone disease
prostate cancer
chronic renal failure
cholestatic disorders
3d
single
null
Medicine
null
11100594-a63a-4c6a-b3fd-b94c8ee7b375
Ability of an orthodontic wire to spring back to its original shape is evaluated by:
Brittleness
Resilience
Tensile strength
Toughness
1b
single
Popularly, the term resilience is associated with springiness, but it means precisely the amount of energy absorbed within a unit volume of a structure when it is stressed to its proportional limit. The resilience of two or more materials can be compared by observing the areas under the elastic region of their stress-s...
Dental
null
0000b5a1-6e5d-40d9-9ddd-d65f7410bb1b
Herpes zoster in geniculate ganglion causes:
Bell's palsy
Ramsay Hunt syndrome
Merkelson Rosenthal syndrome
Frey's syndrome
1b
single
Answer is B (Ramsay Hunt sSyndrome): Herpes Zoster of geniculate ganglion causes Ramsay Hunt Syndrome. The Ramsay Hunt Syndrome is caused by reactivation of Herpes Zoster in the geniculate ganglion and consists of a severe facial nerve palsy associated with a vesicular eruption in the external auditory canal and someti...
Medicine
null
45912b9b-aa7d-4fc1-88f8-f20dc45688b7
Transfer of genetic material in between bacteria through pili is termed as: (E. REPEAT 2012)
Transduction
Conjugation
Transformation
Transfection
1b
single
Ref: Textbook of Microbiology, 8th edition, Ananthna rnyan and Paniker, Pages 63-65Explanation:TYPES OF GENE TRANSFERConjugation: Conjugation is a process of genetic transfer between bacterial cells wherein, a 'donor' bacterium, which contains a plasmid coding for a specialized fimbria called sex pi I us (conjugation t...
Microbiology
Bacterial Genetics
41004212-8bad-4a97-a35d-0b38d239efb7
The main danger with low tension alternating current is
Myoglobinuria
Cardiac arrest
Renal failures
Burns
1b
single
The main danger with alternative current injuries is from alternating current interactions with normal cardiac pacing It can cause cardiac arrest. The electricity itself doesn't usually cause significant underlying myocardial damage. So resuscitation if successful should be lasting. Ref: Bailey and love 27th edition Pg...
Anatomy
General anatomy
23a42e3e-51ae-4913-85d2-c8b082d4f197
Homonymous hemianopia is seen in:
Pituitary adenoma
Optic nerve damage
Post-chiasmic damage
All of the above
2c
multi
Ans. Post-chiasmic damage
Ophthalmology
null
1101ed70-fcca-40de-895b-d3aa6e8f4f2d
Multiple trauma patient, first to be managed is-
Secure airway
Breathing
Conicalbrace
Circulation
0a
single
Ans. is 'a' i.e., Secure airway [Ref: Schuartz 9th/ep. 136; Sabiston 18th/ep. 483J"The first step in managing an injured patient is securing an adequate airway "
Surgery
Initial Assessment
bf63ce31-cffe-4fd8-8d8f-4a41babb0ce1
All are intracellular parasites, except -
Leishmania
Plasmodium
Toxoplasma
None of these
3d
multi
Leishmania-amastigote-lives in reticuloendothelial cells Plasmodium-RBC Toxoplasma-found in reticuloendothelial cells (refer pgno: 63 baveja 3 rd edition)
Microbiology
parasitology
fb89f396-e167-4fdb-8342-0d53d46ffe2d
True statement about drugs used in Parkinsonism is:
Amantadine is a cholinergic drug
Vitamin B6 enhances the L-Dopa action
COMT inhibitors prolong the action of L'-dopa
None
2c
multi
Both entacapone and tolcapone enhance and prolong the therapeutic effect of levodopa-carbidopa in advanced and fluctuating PD Ref KD Tripati 8th ed.
Pharmacology
Central Nervous system
edc70411-13e3-4f4f-a59f-a8ca75f99dd5
Most common hea disease which is associated with maximum moality during pregnancy
>Eisenmenger syndrome
>MS
>AS
>VSD
0a
single
Eisenmenger syndrome This syndrome is secondary pulmonary hypeension that can develop with any cardiac lesion in which pulmonary vascular resistance becomes greater than the systemic vascular resistance and there should also be some right to left shunting. The most common underlying defects are atrial or ventricular se...
Gynaecology & Obstetrics
null
6d09f3ce-e376-4603-ade7-707087d89550
The most diagnostic sign of pregnancy is :
Amenorrhoea
Quickening
Foetal hea sounds
Distention of abdomen
2c
single
Foetal hea sounds
Gynaecology & Obstetrics
null
c0a03838-ac6f-4392-b40a-c4d312a213d1
Which of the following conditions does not cause right axis detion in ECG ?
Lying down posture
End of deep inspiration
Right ventricular hyperophy
Right bundle branch block
0a
single
The electrical axis of the hea is the net direction in which the wave of depolarisation travels. It is measured using an electrocardiogram (ECG). Normally, this begins at the atrioventricular node (AV node); from here the wave of depolarisation travels down to the apex of the hea. The hexaxial reference system can be u...
Medicine
C.V.S
59b98974-8c5a-4dfc-9cea-924c191868ef
70-year-old woman refused to take influenza vaccine, devloped flu. Death happened 1 week after pneumonia. Causes of post influenza pneumonia:
Staphylococcus
Measles
Ligionella
CMV
0a
single
Ans. (a) Staphylococcus Pulmonary complications of influenzae Primary influenza viral pneumonia: Least common but most severe of all pulmonary complications of influenzae Sputum production is generally scanty, but sputum may contain blood. In advanced cases, diffuse rates may be noted X-ray finding shows diffuse inters...
Microbiology
null
a880cd0d-aeb8-48ae-9792-4c3a75a9c81a
What is electrical storm?
> 3 episodes of ventricular tachycardia within 24 hours
> 3 episodes of atrial tachycardia within 24 hours
Electromechanical dissociation
Electrical alternans
0a
single
Electrical storm: Condition in which patient develops recurrent V. tachycardia. Cut off >3 episodes of V.T within 24 hrs. Option C: Electromechanical Dissociation: Terminology used to describe rupture hea which causes pulseless BP|| Option D: Electrical alternans- Variations in QRS amplitude in conditions - C. tamponad...
Medicine
Murmurs
c95bab64-4eb2-4f6b-a197-60522e2c886b
A 20 year old male presented with jaundice for the past 2 weeks. His liver function tests revealed serum bilirubin to be 0.9 mg/dL, SGOT/SGPT to be 1240/1450 IU. He was found to be positive for HBsAg and IgM anti-HEV antibodies and negative for 1gM anti HBc. The most likely diagnosis is
Acute hepatitis with mutant hepatitis B virus
Super infection of hepatitis E virus with chronic hepatitis B infection
Acute hepatitis with wild type hepatitis B virus
Co-infection of hepatitis B and E viruses
1b
single
Ans. b. Super infection of hepatitis E virus with chronic hepatitis B infection In the given question, patient presents with jaundice, deranged LFT (raised SGOT/SGPT), HBsAg positive, IgM anti-HEV antibodies positive and IgM antiHBc-negative. As the patient is IgM anti-HBc-negative, acute hepatitis B is ruled out. As t...
Medicine
null
59d0bbcd-8659-4aee-8d7a-6ccf40858d23
Hormonal vitamin is ?
Niacin
Pyridoxin
Vitamin D
Riboflavin
2c
single
Ans. is 'c' i.e., Vitamin D Active form of vitamin D i.e. 1-25 dihydroxy-cholecalciferol is a vitamin produced in kidney.It acts on intranuclear receptors to regulate gene expressions (transcription factors).
Physiology
null
081c591d-da74-47d2-a55b-071863211fd1
The sigmoid nature of Hb-O2 dissociation curve is because of:
Binding of one O2 molecule increase the affinity for the next O2 molecule.
Alpha chain has more affinity for O2 than beta chain
Beta chain has more affinity for than alpha chain
Hemoglobin in acidic in nature.
0a
single
Ans. is 'a' i.e. Binding of one O2 molecule increases the affinity for next Hb also .Lehninger writes : "Hemoglobin must bind oxygen efficiently in lungs and release oxygen in the tissues, myoglobin, or any protein that binds oxygen with a hyperbolic binding curve, would be ill-suited to this function. A protein that b...
Physiology
Principles of Gas Exchange - Respiratory Membrane
c184de27-39b1-4f43-96ce-0931d8525e40
The most common manifestation of moderate/severe hemophilia A is-
Recurrent hemarthrosis
Recurrent muscle bleeding
Recurrent bleeding from gums
Recurrent Hematuria
0a
single
Ans. is 'a' i.e., Recurrent Hemarthrosis Sites of bleeding in hemophilia||||Intracranial (3-4%)Hemarthrosis (80%)Epistaxis oral gastrointestinal bleedingGenitourinarytracto Revatively rate, compared to other sites of bleedingo M.C site of bleeding in ambulatory patientso Joint bleeding characteristic of severe diseaseo...
Medicine
C.V.S.
798bea47-d43e-4df4-9825-fdb9c24c2e87
A 34-year-old man who works as a carpenter presents with symptoms of jaw discomfort, dysphagia, and pain as well as stiffness in his neck, back, and shoulders. On examination, he is unable to open his jaw, his proximal limb muscles are stiff as is his abdomen and back, but the hands and feet are relatively spared. He o...
toxoplasmosis
tetanus
syphilis
Streptococcus
1b
multi
Patients with tetanus develop hypertonus, seizures, respiratory distress, and asphyxia unless they are treated with diazepam and muscle relaxants. The treatment of tetanus requires diazepam, muscle relaxants, antitoxin, respiratory care, and managing autonomic dysfunction. Antibiotics are given but are probably of litt...
Medicine
Infection
8d205524-0254-4768-9a29-6fff52e5482e
12 years male came with swelling of lower end tibia which is surrounded by rim of reactive bone. What is most likely diagnosis?
GCT
Brodie's Abscess
Hyper PTH
Osteomyelitis
1b
single
* GCT - occurs around 20-40 years of age* Hyperparathyroidism - typically in a female around 30 years of age; presents with lytic lesion* Brodie's abscess - swelling in the lower end of tibia and radiological evidence of cavity surrounded by a halo of sclerosis (rim of a reactive bone) point towards brodie's abscess.
Orthopaedics
NEET 2019
ff4cb67f-2bbb-42b0-9544-7903f89b1f89
Touch is carried by:
A beta
A delta
C fibers
Both 1 and 2
3d
multi
Numerical classification of sensory nerve fibers:
Physiology
null
d6edc3b8-2219-4380-82ee-f2b432bc5ae0
There are hard dark brown lesions on the labial surface of all four primary cuspids in seven year old child, the teeth are not painful and scraping with spoon excavator yields only a few flecks of dried discoloured dentin. What are these lesions?
Active carious lesions
Arrested carious lesions
Local enamel hypoplasia
Abrasion
1b
multi
Arrested caries With the shift in the oral conditions, even ad­vanced lesions may become arrested. Arrested caries involving dentin shows a marked brown pigmentation and induration of the lesion . There are hard dark brown lesions, the teeth are not painful and scraping with spoon excavator yields only a few flecks of d...
Dental
null
c17aaaa3-6a60-4948-b17d-44938e7c7c5c
All the following are the objectives of access cavity preparation EXCEPT
To remove all caries
To completely unroof the pulp chamber
To achieve straight line access to apical foramen
To have converging axial walls for preservation of tooth structure
3d
multi
null
Dental
null
fc1a3625-18c7-488d-9ff7-f77a8163461a
All are included in Kangaroo Mother Care except:
Skin to skin contact
Early discharge and follow up
Free nutritional supplements
Exclusive Breast feeding
2c
multi
KANGAROO MOTHER CARE is for prevention of neonatal hypothermia in low bih weight/premature newborns: Skin -to -skin positioning of newborn on mother's chest. Adequate nutrition through breast feeding. Early discharge and ambulatory care. Suppo to the mother and family for child care.
Social & Preventive Medicine
Obstetric Care in RCH: Visits, IFA, TT, MCH Indicators
3a63b379-07ed-427d-8c23-ae4c5c0c10b7
In malignant hypeension hyperplastic aeriosclerosis is seen in all except:
Hea
Kidney
Pericardial Fat
Peripancreatic fat
0a
multi
. Hea
Pathology
null
16562263-4bef-4a37-b1ce-e4091b941af2
A 65-year-old woman who has a 12-year history of symmetrical polyahritis is admitted to the hospital. Physical examination reveals splenomegaly, ulcerations over the lateral malleoli, and synovitis of the wrists, shoulders, and knees. There is no hepatomegaly. Laboratory values demonstrate a white blood cell count of 2...
Basophilia
Lymphopenia
Granulocytopenia
Lymphocytosis
2c
multi
(Braunwald, 15/e, pp 369,1932.)Felty syndrome consists of a triad of rheumatoid ahritis, splenomegaly, and leukopenia. In contrast to the lymphopenia observed in patients who have systemic lupus rythematosus, the leukopenia of Felty syndrome is related to a reduction in the number of circulating polymorphonuclear leuko...
Surgery
null
7bf5390b-d5b8-469e-bc69-fc7e5698226b
Superior pancreaticoduodenal aery is a branch of
Hepatic aery
Splenic aery
Gastroduodenal aery
Inferior mesenteric aery
2c
single
The superior pancreaticoduodenal aery is an aery that supplies blood to the duodenum and pancreas. It is a branch of the gastroduodenal aery, which most commonly arises from the common hepatic aery of the celiac trunk, although there are numerous variations of the origin of the gastroduodenal aery. The pancreaticoduode...
Anatomy
Abdomen and pelvis
505a2b54-a2b1-456f-b8c4-21a73af773ba
Styloid process is derived from
First arch
Second arch
Third arch
Fouh arch
1b
single
The styloid process,the stylohyoid ligament and muscle are derived from the second branchial arch. REF.BDC VOL.3,Fifth Edition,
Anatomy
Head and neck
4db53f9c-91bc-4a5d-af83-9623444bfc1f
Most common cause of Tinea capitis -
M. canis
Epidermophyton floccosum
T. Tonsurans
T. concentricum
0a
single
(Harrison) have mentioned that T tonsurans is the most common cause of T capitis. But most textbooks of dermatology have mentioned that Ectothrix is the most common type of T capitis and is caused mostly by M canis. Thus, the answer of this question is M canis. Tinea capitis: - Location of Lesions - Scalp hair Endothri...
Microbiology
Mycology
b9cf5fea-7fde-4eaf-ab9e-0c3a550b82bf
Which of the following anti-HIV drug should never be given as rechallenge once a history of producing allergic reaction with the drug is known
Lamivudine
Abacavir
Zidovudine
Nelfinavir
1b
multi
null
Pharmacology
null
b7faa894-2206-45ff-8fda-5f0744708a46
A patient taking 120 ml alcohol everyday since last 12 years is brought to the hospital by his wife and is diagnosed to have alcohol dependent syndrome. Which of the following drug should be avoided in the management?
Phenytoin
Di sulfiram
Naltrexone
Acamprosate
1b
single
Ans. b. Disulfiram Disulfiram should not be used in alcohol dependent patients as it can cause severe disulfiram-ethanol reaction. Alcohol sensitizing drugs (Deterrent agents) DisulfiramQ Sulfonylureas (especially ChlorpropamideQ Citrated calcium carbimide (CCC) Cephalosporins: MetronidazoleQ CefoperazoneQ NitrafezoleQ...
Radiology
null
47c8a088-68a9-4604-a1be-a315054e3c65
Histology of Alport syndrome -a) Foamy cells in interstitiumb) Foamy cells in tubular epithelial cellsc) Thickening of GBM > 100 nmd) Thinning of GBM < 100 nme) Intimal proliferation
b
c
ad
ab
2c
single
Histological characteristics of Alport’s syndrome: • Diffuse basement membrane thinning                                                        • Vascular sclerosis • Foam cells in interstitium                                                                             • Tubular atrophy • In advanced stage there is foca...
Pathology
null
b965e3af-a1d1-4468-94a3-edd880ed4890
hyper ammonemia is a side effect of
valproate
amitriptilline
amisulpride
olanzapine
0a
single
LETHAL SIDE EFFECTS OF VALPROATE - Hyperammonemia - Pancreatitis - Hepatic failure - Neural tube defects - Thrombocytopenia MINOR SIDE EFFECTS OF VALPROATE - Hair loss - PCOD - WEIGHT GAIN - TREMORS Ref.kaplon and sadock, synopsis of psychiatry,11 th editioon, pg no.935
Anatomy
Pharmacotherapy in psychiatry
ee9ebdf2-e24b-4c1f-af2e-e90807107dd8
Most severe form of hereditary spherocytosis is caused by the mutation of -
Ankyrin
Alpha spectrin
Beta spectrin
Band 3
1b
single
. Alpha spectrin
Pathology
null
98c689f7-be9a-4ee7-8de4-1e232ae75534
A 40 year old woman reports with the complaint of burning sensation in the mouth. Clinical examination reveals lesions consisting of radiating white striations in a retiform arrangement affecting buccal mucosa, tongue, lips & gingiva bilaterally. An incisional biopsy is suggestive of lichen planus. The following are di...
Atrophic Lichen Planus
Hypertrophic Lichen Planus
Bullous Lichen Planus
Verrucous Lichen Planus
3d
multi
The different forms of Lichen planus are reticular form, bullous form, atrophic form, hypertrophic and erosive forms. Verrucous variant is seen in Leukoplakias.
Pathology
null
77413bc7-a69b-49b4-9e14-9bf8053f547b
All are true about Juvenile CML except
Philadelphia chromosome is absent
Associated with Neurofibromatosis-1
Presents with anaemia, low HbF, leucocytosis
Most common in less than 2 years of age
2c
multi
It presents with anaemia, thrombocytopenia, high HbF and leukocytosis.
Pediatrics
null
59700ef1-9802-40ca-b268-34274af7efa3
Riociguat is used in the treatment of:
Gouty ahritis
Rheumatoid ahritis
Chronic thromboembolic pulmonary hypeension
Obesity
2c
single
Riociguat a soluble guanylate cyclase stimulator. It is the only therapy approved by USFDA for inoperable CTEPH (Chronic thromboembolic pulmonary hypeension). Best treatment for operable cases is pulmonary thromboendaerectomy done in expe centres. Reference: Ghofrani HA, D'Armini AM, Grimminger F, Hoeper MM, Jansa P, K...
Medicine
All India exam
73e91695-205d-4b65-bc19-e61cc1de5bcf
A patient with cancer developed extreme degree of radiation toxicity. Further history revealed that the dose adjustment of a particular drug was missed during the course of radiotherapy. Which of the following drugs required a dose adjustment during radiotherapy in order to prevent radiation toxicity?
Vincristine
Dactinomycin
Cyclophosphamide
6- Mercaptopurine
1b
single
Ans. (B) Dactinomycin(Ref: Katzung 10th/894)Anthracyclines and actinomycin-D (dactinomycin) can cause severe radiation toxicity. This is known as radiation recall syndrome.
Pharmacology
Chemotherapy: General Principles
7e4ccd16-0440-4867-8a25-f733af13b754
A young patient presents with a massive injury to proximal duodenum, head of pancreas and distal common bile duct. The procedure of choice in this patient should be :
Roux-en-Y anastomosis
Pancreaticoduodenectomy(Whipple's operation)
Lateral tube jejunostomy
Retrograde jejunostomy
1b
single
null
Surgery
null
eb85eec7-e717-4d28-a58c-f3fe8fa1a0f9
Resin matrix system used in the composite shown below is:
Ormocers
POSS
Siloranes
Giomers
1b
single
Polyhedral Oligomeric Silsesquioxane (POSS): POSS molecules are 12-sided silicate cages produced from silane and functionalized to copolymerize with other monomers. POSS is a molecule-sized hybrid organic-inorganic oligomeric compound that can disperse homogeneously in compatible monomers and become covalently incorpor...
Dental
null
ac658acb-8cdc-4c79-8cd2-0833c5972df4
Organism involved in smooth surface caries is 1. Streptococcus mutans 2. Actinomyces viscosus 3. Lactobacillus 4. Campylobacter
only 1
only 2
1 and 3
All of the above
0a
multi
null
Pathology
null
06bb2c02-5124-4c15-a8a9-b435f5cc3dff
Monochorlonic monoamniotic twin occurs if; division occurs :
Before 24 hours
1-4 days
4-8 days
8 days
3d
single
8 days
Gynaecology & Obstetrics
null
86798aef-0077-456c-9dff-aab8372048d2
Many signaling pathways involve the generation of inositol trisphosphate (IP3) and diacylglycerol (DAG). These molecules
Are first messengers
Activate phospholipase C
Are derived from PIP2
Can't activate calcium calmodulin-dependent protein kinases directly or indirectly
2c
single
IP3 DAG are secondary messengers derived from PIP2 they are present in the cell membrane where IP2 crosses the cell membrane and DAG doesnot. Ref: KD Tripathi 8th ed.
Pharmacology
All India exam
97e7aaa0-6279-461e-93f2-976e117bc631
Alpha fetoprotein is raised in all except:September2011
Teratocarcinoma
Down syndrome
Embryonal cell carcinoma
Hepatocellular carcinoma
1b
multi
Ans. B: Down syndromeAFP is produced by hepatocellular carcinomas, yolk sac remnants in the gonads, and occasionally teratocarcinomas and embryonal cell carcinomas.
Pathology
null
f074568a-aa7b-4800-bc7a-7a722a48426a
A Neonate is brought with history of not having passed meconium on examination there is no anal opening but a dimple. Investigation of choice is ?
X-ray erect posture
X-ray supine posture
Gastrograffin study
Inveogram
3d
single
Ans is d i.e. In veogram The radiograph is taken in inveed position
Surgery
null
62a0645d-d309-41b2-a9aa-9d10efb30f2b
Sequence of the substances used in the Nalgonda's technique for defluoridation of water: March 2011
Lime and then soda
Alum and then soda
Lime and then alum
Alum and then lime
2c
single
Ans. C: Lime and then alum Nalgonda technique involves addition of 2 chemicals (lime and alum) in sequence followed by flocculation, sedimentation and filtration The Nalogonda technique It is named after the village in India where the method was pioneered It employs flocculation principle Nalgonda technique is a combin...
Social & Preventive Medicine
null
c02e766d-468a-4821-9864-6b93be1ed3ca
Calculate IMR if in a population of 100000 there are 3000 live bihs in a year and 150 infant deaths in the same year -
75
18
5
50
3d
single
Ref: Park 24th edition
Social & Preventive Medicine
All India exam
0afa7a4c-283e-4b76-8e21-632282f9548c
Most common cause of air borne contact dermatitis is?
Parthenium hysterophorus
Poison ivy
Poison oak
Pollen
0a
single
ANSWER: (A) Parthenium hysterophorusREF: Neena khanna 3rd ed p. 86-89Most common cause of:Allergic contact dermatitis due to metal: NickelAllergic contact dermatitis in Indian females: On hands is detergents, on forehead is para tetra butyl phenol in bindi, ear lobule is nickelAir borne contact dermatitis and plant der...
Skin
Dermatitis Erythema
15a5029b-c16e-4348-9c7c-20ef62dbd113
ASHA is posted at:
Village level
Primary Health Centre
Community Health Centre
Subcentre
0a
single
ASHA stands for "Accredited Social Health Activist" and is created by the NHRM (National Rural Health Mission) which was formed by the Government of India on 5th April, 2005 for a period of seven years (2005-2012). The ASHA is employed in the rural area at the village level. Ref: Park textbook of Preventive and Social ...
Social & Preventive Medicine
null
20941356-e215-4348-8f8b-2667009a774c
A young male patient presents with LDL 600 mg/dl, triglycerides 160 mg/dl. What would be the most likely finding on physical examination -
Tendon xanthoma
Lipemiaretinalis
Eruptive tuberous xanthomas
Xanthelesma
0a
single
Xanthoma tendinosum (also tendon xanthoma or tendinous xanthoma) is clinically characterized by papules and nodules found in the tendons of the hands, feet, and heel. Also associated with familial hypercholesterolemia (FH) Tendon xanthomas are associated with type II hyperlipidemia, chronic biliary tract obstruction, p...
Medicine
Miscellaneous
16e1e0fe-a5e9-44a9-8678-c79a5dff43aa
Gutter fracture results from -
Injury with a large round object
Bullet injuries
Automobile accident
Falling from a height
1b
multi
Gutter fracture : When a part thickness of bone is removed (fracture involves only the outer table of skull), e.g. glancing (oblique) bullet wounds in firearm injury.
Forensic Medicine
null
f9ddda01-a155-4a02-9c6e-81046b2bbd37
Which of the following is a pa of Mobius syndrome except?
Decreased chest movements
Bilateral facial involvement
Unilateral or bilateral abducent nerve involvement
Ataxia
3d
multi
The classically accepted diagnostic criteria include: 1) facial paralysis or weakness affecting at least one but usually both sides of the face (7th cranial nerve), 2) paralysis of sideways (lateral) movement of the eyes (6th cranial nerve); and 3) preservation of veical movements of the eyes. Other symptoms that somet...
Medicine
C.N.S
9c44eace-4c8b-4dd6-8849-3720837092cd
Phytobezoars are composed of
Hair
Vegetable Matter
Undigested food
Desquamated epithelial cells
1b
single
Answer- B. Vegetable MatterPhytobezoars are composed of vegetable matter and, are usually seen in association with gastroparesis or gastric outlet obstruction.
Surgery
null
a40ee554-9b63-4cee-af21-d7fde054a4c3
Mummification refers to -
Hardening of muscle after death
Colliquative putrifaction
Saponification of subcutaneous fat
Dessication of a dead body
3d
single
Mummification is drying and shrinking of cadaver from evaporation of water and general appearances of the body are preserved. Dr. Narayana Reddys Synopsis of Forensic Medicine & Toxicology 27 th edition pg. 87.
Forensic Medicine
Death and postmortem changes
8417f7c8-3e5d-4be9-93fb-97a75e3b489d
Anticancer drug causing nephrotoxicity: September 2009
Imitanib
Irinotecan
fosfestrol
Cisplatin
3d
single
Ans. D: Cisplatin Drugs causing nephrotoxicity: Chemotherapy and Immunosuppressants drugs causing nephrotoxicity: - Cisplatin - Methotrexate - Mitomycin - Cyclosporine - Ifosphamide (Causes Fanconi's Syndrome) Antibiotics: - Aminoglycoside - Sulfonamides Amphotericin B - Foscarnet Quinolones (e.g. Ciprofloxacin, Levofl...
Pharmacology
null
f4f43518-49a3-49b0-b776-b98b415753c2
Non hormonal drug to prevent post menopausal osteoporosis is:
Alendronate
Estrogen
Raloxifene
Parathyroid
0a
single
Alenderonate, etidronate, pamidronate, and Ibandronate are bisphosphonates which inhibit bone resorption, and are very effective for both osteoporosis prevention and treatment. Uses: • First line drugs for treating postmenopausal osteoporosis • Paget’s disease • Osteolytic bone metastasis. Caution: Patient should be in...
Gynaecology & Obstetrics
null
10a6c105-dd3b-49dc-8416-b3b50cf5636b
The length of the eyeball is
12mm
16mm
24mm
30mm
2c
multi
Eyeball - Not a perfect sphere but an Ablate spheroid Dimensions of an adult eyeball Anteroposterior diameter - 24 mm Horizontal diameter - 23.5 mm Veical diameter - 23 mm Circumference - 75 mm Volume - 6.5 ml Reference : Khurana Ophthalmology; 4th edition Page 3
Ophthalmology
Anatomy, Development and clinical examination
ff86e8ba-426f-4174-8727-ef061926e002
Gerota's fascia is:
Renal fascia
Fibrous capsule
Layer of perirenal fat
Layer of pararenal fat
0a
single
Ans. A: Renal fascia
Anatomy
null
fd9bfe40-d48e-4c3b-8458-849dda6b07aa
Which of the following autistic spectrum disorder carries good prognosis?
Childhood autism
Rett's disease
Heller's syndrome
Asperger's syndrome
3d
single
Asperger's syndrome is characterized by impaired social interaction and stereotyped behavior but no intellectual disability and no language disturbances,hence carries good progrosis.
Psychiatry
null
7dc8ace1-69f6-480b-ae72-dc8cdc8f09f2
All are true about colles fracture except ?
In old age
Dorsal shift
At coico-cancellous junction
Garden spade deformity
3d
multi
Ans. is 'd' i.e., Garden spade deformity COLLES FRACTURE Colle's fracture is an extra-aicular fracture at the distal end of radius, at its coico-cancellous junction. It is the most common fracture in person over 40 years of age and especially in women after menopause (Postmenopausal females). The association of the fra...
Surgery
null
2dd6f053-c9ed-433c-9883-0922530ba7df
All of the following muscles are composite muscles Except:
Pectineus
Rectus femoris
Adductor magnus
Biceps femoris
1b
multi
B i.e., Rectus femorisFlexor digitorion profundus (FDS), Adductor magnus, biceps femoris, pectineus and quadriceps femoris (not rectus fernoris)(2 are all composite muscles. Rectus femoris is only a pa of composite of 4 muscles known as quadriceps femoris.
Anatomy
null
2aed95ce-ec0c-4e31-b573-3f05dfefa66f
Antenatal maternal HIV diagnosis is of impoance in -
To prevent veical transmission
To terminate
To discharge
To isolate the patient
0a
single
Ans. is 'a' To prevent veical transmission . HIV infected mother can transmit the virus to fetus/infant during pregnancy, during delivery or by breast feeding. . Early diagnosis and antiretroviral therapy to mother and infant significantly decrease the rate of intrapaum and perinatal transmission (Veical transmission) ...
Microbiology
null