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135
2107f0bc-b5e5-433a-b635-6a0491bdee6d
Reduced salivary flow following irradiation is dose dependent. At what dose does the flow reach essentially zero:
4000 rads
5000 rads
6000 rads
7000 rads
2c
multi
null
Radiology
null
694d4676-b521-444e-99f8-685007921d8d
True statement about PPV is
It increases with prevalence
It decreases with prevalence
No relation with prevalence
Doubles with decrease in prevalence
0a
multi
null
Social & Preventive Medicine
null
0a49c555-0985-4dae-9428-430209599028
All of the following drugs may cause Hirsuitism, except-
Danazol
Phenytoin
Norethisterone
Flutamide
3d
multi
Ans. is `d' i.e., Flutamide Drugs causing Hirusitism Androgenic drugs o Acetazolamide o Testosterone o Anabolic steroids o Danazole o Androgenic progestins o Coicotropin (Norethisterone) o Metyrapone o Dihydroepiandrosterone Non - androgenic drugs o Phenytoin o Penicillamine o Triamterene - hydrochlohiazide o Cyclospor...
Pharmacology
null
8dcf1a5f-3b5f-45c0-b2b7-7313c53e74f7
Precapillary sphincter relaxation occurs due to:
Local chemicals
Sympathetic stimulation
Circulating catecholamines
Capillary filling
0a
single
Precapillary sphincters are controlled mainly by the local concentration of tissue metabolites. Precapillary sphincters are considered as pa of the precapillary resistance vessels; they determine the size of the capillary exchange area which is perfused at any given moment in the tissue. In the triple response, relaxat...
Physiology
Circulation
b0389cf2-cdf5-4a2e-8121-4346cfaeac6c
Rivastigmine and Donepezil are drugs used predominantly in the management of which of the following conditions?
Depression
Dissociation
Delusions
Dementia
3d
single
In Alzheimer's disease the most common cause of dementia, there is a reduction in the activity of acetylcholine within the brain due to loss of cholinergic activity within the brain due to loss of cholinergic neurons in the nucleus basalis of Meyne . Both Rivastigmine and Donepezil are cholinesterase inhibitors used in...
Psychiatry
null
1999b372-2737-43f7-8eee-9072733fcfdc
All are used to remove potassium in hyperkalemia except
Cation exchange resins
Diuretics
Beta 2 agonists
Dialysis
2c
multi
The treatment of hyperkalemia is divided into three stages: Immediate antagonism of the cardiac effects of hyperkalemia 10 mL of 10% calcium gluconate (3-4 mL of calcium chloride), infused intravenously over 2-3 min with cardiac monitoring Rapid reduction in plasma K+ concentration by redistribution into cells. 10 unit...
Medicine
Fluid and electrolytes
5bee6545-b02e-4319-a851-0f6d2ba69d85
OSHA guidelines for needle and other sharp injuries requires all, Except
Record maintaining of all injuries
Information and training
Pre-exposure prophylaxis
Post-exposure porphylaxis
2c
multi
Pre-exposure prophylaxis (Ref: Workers in many different occupations are at risk of exposure to bloodborne pathogens, including Hepatitis B, Hepatitis C, and HIV/AIDS. In 1991, OSHA. (Occupational Safety and Health Administration) issued the Bloodborne Pathogens Standard to protect workers from this risk. In 2001, in r...
Surgery
null
616c6121-cf4a-4f56-9509-e46790c13f51
Constellation of neuropathy, muscle weakness and wasting, cardiomegaly, edema, ophthalmoplegia, confabulation strongly suggest: KCET 13
Hysteria
Thiamine deficiency
Lead poisoning
Intracerebral hemorrhage
1b
single
Ans. Thiamine deficiency
Forensic Medicine
null
45505bbf-e125-48ec-9749-01b8f38c957a
Citrate as a sole source of carbon is utilized by
Staphylococcus
Salmonella
Shigella
Escherichia
1b
single
Citrate is used by salmonella as sole source of carbon But citrate test positive: Salmonella Typhimurium Salmonella Paratyphi A is citrate negative Ref: Elmer W Koneman 5th ed Pg 186
Microbiology
Bacteriology
7e8cb453-ea1f-42a7-9f81-95b9c1dbe824
The superior oblique muscle is supplied by?
3rd cranial nerve
4th cranial nerve
5th cranial nerve
6th cranial nerve
1b
single
The superior oblique muscle is supplied by4th cranial nerve.
Anatomy
null
e7a4bd41-21c2-4ef1-8426-a476c7d0a0d1
Increased insulin receptors are seen in
Obesity
Starvation
Acromegaly
None
1b
multi
Increased circulating levels of insulin reduce the number of receptors--down-regulation of receptors--and decreased insulin levels increase -the number of receptors - up Regulation.The number of receptors per cell is increased in starvation.Ref: DM Vasudevan, 7th edition, page no: 319
Biochemistry
Endocrinology
087bc458-396b-4d79-b73d-78fe6c781174
Which of the following vitamin is NOT required from diet?
Nicotinic acid
Ascorbic acid
Vitamin-A
Vitamin-D
3d
single
Vitamin D is synthesized in the skin. 7-Dehydrocholesterol (an intermediate in the synthesis of cholesterol that accumulates in the skin) undergoes a nonenzymic reaction on exposure to ultraviolet light, yielding previtamin D. This undergoes a fuher reaction over a period of hours to form cholecalciferol, which is abso...
Biochemistry
null
cb41f1e7-911c-4dd9-949f-a27bbb6098d5
Diagnosis of x linked agammaglobulinamia should be suspected if
Absent tonsils and no palpable lymph nodes on physical examination
Female sex
High iso hemagglutinin titers
Low CD3
0a
single
Ref Robbins 9/e p240-241 Classically, this disease is characterized by the following: * Absent or markedly decreased numbers of B cells in the circulation, with depressed serum levels of all classes of immunoglobulins. The numbers of pre-B cells in the bone marrow may be normal or reduced. * Underdeveloped or rudimenta...
Anatomy
General anatomy
ee0344be-5ffe-44f4-a4a1-ad7dbac16727
Metabolic complications of subtotal gastrectomy with Billroth I or Billroth II reconstruction include:
Anemia
Reactive hypoglycemia
Dumping syndrome
All of the above
3d
multi
Anemia develops in as many as 30% of patients within 15 years of surgery. The cause is multifactorial and includes malabsorption of iron, folate, and vitamin B 12. A metabolic bone disease occurs in as many as 33% of patients, is similar to osteomalacia, and is probably a result of malabsorption of calcium and vitamin ...
Surgery
Stomach & Duodenum
8579091a-2503-478d-9a9c-4c4702236e21
Antiviral drug having dual antiviral activity against HIV and HBV is :
Enfuvirtide
Emtricitabine
Abacavir
Entecavir
1b
single
null
Pharmacology
null
79460587-d579-46dd-ada9-5066afa95aaa
Palmar erythema is seen in:
CCF
ARF
CRF
Hepatic failure
3d
single
A symmetrical and slightly warm area of erythema on the thenar and hypothenar eminences of the palm in chronic liver disease patients is referred to as palmar erythema. Features of Palmar Erythema May have a mottled appearance or blanch when pressed. Not associated with pain, itch or scaling. May involve the palmar asp...
Medicine
Misc.
84873d0c-bacd-4889-ac0f-67b8590db6b7
In diabetic pregnancy least common is:
Caudal regression syndrome
Anencephaly`
VSD
Spina bifida
0a
single
Caudal regression syndrome
Gynaecology & Obstetrics
null
edf5a7fc-af51-4b32-8579-b1f148727b30
First internal organ to putrefy
Hea
Brain
Larynx
Kidney
2c
single
Larynx & trachea -Stomach, intestines & Spleen -Liver (foamy liver) lings-Brain -Hea - Kidneys, bladder -Prostate, uterus-Skin, muscle, tendon - Bones Larynx is the earliest organQto putrefy. Nulliparous uterusQis the last organQto putrefy, gravid uterus and uterus soon after delivery putrefies rapidly In males, Prosta...
Forensic Medicine
Thanatology
208cc4a4-b936-4784-9f24-df206a1d165d
In an infrabony pocket the junctional epithelium lies
Apical to the root apices
Apical to the crest of the alveolar bone
Coronal to the crest of the alveolar bone
At the level of the alveolar bone
1b
single
null
Dental
null
cf894587-d08f-4c14-9359-46314e0bdae9
All predispose to torsion testis, except:
Inversion testis
Epididymo orchitis
High investment of tunica vaginalis
Separation of epididymis from body of testis
1b
multi
Ans: b (Epididymo orchitis) Ref: Bailey & Love, 24th ed, p. 1405Epididymo orchitis does not predispose to torsion testisPredisposing factors for torsion of testisa) Inversion of the testis (most common)b) High investment of the tunica vaginalis cause testis to hang within the tunica like a clapper in a bellc) Separatio...
Surgery
Testis & Scrotum
335d33a8-374e-4f3c-a826-0aff9ef114a8
Distant direct ophthalmoscopy is done at a distance of:
20 cm.
25 cm.
50 cm.
100 cm.
1b
single
B i.e. 25 cm
Ophthalmology
null
70d7bc1f-a4c9-480b-835d-803600e9c418
Bhore committee advised -
Integration of health services
100% immunisation
Eradication of povey
Minimum needs programme
0a
single
One of the impoant recommendations of the Bhore Committee was Integration of preventive and curative services at all administrative levels (refer pgno:873 park 23 rd edition)
Social & Preventive Medicine
Health education & planning
c9519750-1f46-449d-97af-9c91b1d9c9aa
Positively charged particle can be easily filtered than negatively charged particle because
Positively charged particles are of small size
Presence of positive charged particles on filtering membrane attracts positively charged particle
Presence of negatively charged sialoproteins on filtering membrane repels negatively charged particles and allows positively charged particles.
None of the above
2c
multi
Epithetial cells of Bowman's capsule deposits negatively charged sialoproteins in basement membrane. It repels negatively charged particles and attracts positively charged particles.
Physiology
null
b67fde7c-787f-4e4c-a7fe-d543868f586f
Ideal number of antenatal visits:
14-Dec
8-Jun
9-Jul
11-Oct
0a
single
Ideally the schedule of antenatal visits should be : Monthly visit upto 28 weeks Two weekly visit between 28 and 36 weeks Weekly visit from 36 week onwards This means a total of 12-15 visits. Ref: Datta Obs 9e pg 89.
Anatomy
General obstetrics
8156240c-3975-4a9d-b583-bff08bb0cef0
Gastric lavage is contraindicated in?
Organo-Phosphosphate poisoning
Hydrocarbons
Bicarbonate
PCM toxicity
1b
single
Contraindications of gastric lavage: Absolute: Corrosives to prevent fuher damage from perforation (except carbolic acid - causes leathery mucosa of stomach - no risk of perforation). Relative: 1. Convulsant - may induce more convulsions 2. Comatose - |change of aspiration.3. Varices - can cause bleeding 4. Volatile - ...
Forensic Medicine
FMGE 2018
7f1d31df-f03d-41ff-9a47-19ba9530c392
Ten years after diagnosis of total proctocolitis this patient undergoes colonoscopy and biopsy reveals high-grade dysplasia in 2-10 specimens. What should the physician recommend?
Repeat colonoscopy in 1 year
Increase steroid dosage
Early repeat colonoscopy and biopsy area again
Total proctocolectomy
3d
single
Risk of dysplasia and colorectal cancer is higher in ulcerative colitis than in the general population. The severity, duration, and anatomic extent of the inflammation are risk factors for the development of dysplasia and cancer. These cancers do not seem to follow the adenoma carcinoma sequence and can arise in flat m...
Surgery
Small & Large Intestine
74a2f2d2-97c5-41da-9c6d-56ebbe1dac97
Gynaecomastia is caused by?
Flutamide
Cimetidine
Pyrazinamide
Methotrexate
1b
single
Ans. (b) CimetidineRef Appendix-39 for 'Drugs causinggynaecomastia"
Pharmacology
Adverse Drug Effect
1c8c69e1-d8bb-4013-a37b-86e95153f5e5
All of the following are true about Carcinoma Penis except
Spreads bloods except
Most common type is verrucous
Slowly progreeive
Leads to erosion of artery
1b
multi
Most common type of Carcinoma Penis is Squamous cell carcinoma.
Surgery
null
e688635a-7073-4a6c-9511-a9890a71d691
Drug not used in SIADH is :
Demeclocycline
Desmopressin
Restriction of free water intake
3% NaCl
1b
single
null
Pharmacology
null
51278ab1-8b43-48ec-b552-15e940307084
For porcelain fused to metal crown, the porcelain should have?
High fusion expansion
High fusion temperature
Linear coefficient of thermal expansion less than that of metal
Linear coefficient of thermal expansion more than that of metal
2c
single
null
Dental
null
69daa0b7-e55b-43e5-86df-3adc02c5b8fd
RPGN occurs in all except
SLE
Post streptococcal glomerulonephritis
Diabetic nephropathy
Good pasture's syndrome
2c
multi
null
Pathology
null
7989d65b-3f01-40a7-b8d6-d1d65f03d7bc
Quartz in Dental porcelain is
Strengthener
Binder
Pigment
Crack minimizer
0a
single
null
Dental
null
cb32a48d-7e93-4bdd-b549-77fefc85ac28
Most common heart lesion in down syndrome:
Endocardial cushion defect
ASD with ostium secundum
VSD
Coarctation of aorta
0a
single
a. Endocardial cushion defect(Ref: Nelson's 20/e p 610-614)Most common cardiac defect in Down syndrome is Endocardial cushion defect or Atrioventricular septal defect
Pediatrics
Genetics And Genetic Disorders
a485fee4-ad16-498d-91f6-4c9644581c28
Most common infection occurs in transplant recipients:
Cytomegalo virus
Epstein Barr virus
Hepatitis virus
Polyoma virus
0a
single
Ref. Textbook of Microbiology and Immunology BY Parija. Page. 487   Most common infection is CMV. Below is the table of the infections in transplant recipients (Very important from Harrisons)
Unknown
null
0b785481-e4e1-4542-90bb-ecfa423780ea
Which bone scan is done to detect metastasis bone
Tc99 MDP
Th201
Tc99 DMSA
Tc99 sulphur colloid
0a
single
Tc99 MDP - bone scanTh201-myocardial imagingTc99 DMSA-Renal coical scintigraphyTc99 sulphur colloid - Liver and spleen scintigraphy(Ref: Radiology Review ManualBy Wolfgang Dahne 6thEtd, Page no:1084)
Radiology
All India exam
faf919cc-3104-4c8a-b346-98ca5037a927
Cottle test is used for ?
Septal perforation
Rhinophyma
Choanal atresia
DNS
3d
single
Ans. is 'd' i.e., DNS Cottle test : It is used to test nasal obstruction due to abnormality of nasal valve as in case of deted nasal septum. In this test, cheek is drawn laterally while the patient breathes quietly. If the nasal airway improves on the test side, the test is positive, and indicates abnormality of the ve...
ENT
null
3c38d7c0-1f3d-47e7-9b84-320151fc7b56
All of the following poison's are dialyzable except-
Ethylene glycol
Methanol
Barbiturates
Copper sulphate
3d
multi
Hemodialysis is not useful in copper sulfate poisoning. It is useful in poisoning with other three given options.
Forensic Medicine
null
c6390e2d-66a5-4352-8ee8-d9f11b66bcf8
Colon contains -
Parietal cells
Chief cells
Brunner's gland
Goblet cells
3d
single
Ans. is 'd' i.e., Goblet cells o Large intestine (colon) contains large number of goblet cells,Part of gutHistological featureStomachGastric pits and glands. Gastric glands contain (from above downwards): Mucus neck cells, parietal cells, chief cells.DuodenumBrunner's glands in the submucosaJejunumSolitary lymphoid nod...
Anatomy
Large Intestine, Rectum, and Anal canal
7ef69042-a124-4b52-a445-a2dc53cb26af
The Investigation of choice in a 55-year-old postmenopausal women who has presented with postmenopausal bleeding is:
Pap smear
Fractional curettage
Transvaginal ultrasound
CA-125 estimation
1b
single
Common causes of postmenopausal bleeding Genital malignancy (Me) Decubitus ulcer DUB. Urethral caruncle. Senile endometritis DIAGNOSIS Speculum Examination If a growth is found, punch biopsy is to be taken. If no growth is visible and the cervix looks apparently healthy- Cervical smear Aspiration cytology Fractional cu...
Anatomy
All India exam
0b92e688-8522-41e8-8606-e63f193c78a4
In spinal anaesthesia the segmental level of:
Sympathetic block is lower than the sensory block
Sympathetic block is higher than the sensory block
Motor block is higher than the sensory block
Sympathetic, motor and sensory block has the same level
1b
single
Spinal anaesthesia creates a zone of differential blockade in which sympathetic fibres are blocked two segments higher and motor fibres are blocked two segments lower than the level of sensory block.
Pharmacology
Anaesthesia
fea332b4-7a9e-4df8-ac1b-ae0497a6dd7a
All of the following agents are used in glaucoma treatment, except
Apraclonidine
Timolol
Pilocarpine
Metoprolol
3d
multi
Ref:KD Tripathi 7th edition (page.no: 127,144,153) Katzung 10/e p103 metoprolol is b1 selective blocker, so it can't be used for glaucoma. b2 receptor is present in the eye. so drugs acting on beta 2 should be given. Other drugs used for glaucoma are- b blocker- Timolol,Betaxolol, a agonist ; Apraclonidine,Brimonidine,...
Pharmacology
Autonomic nervous system
c157af3f-4252-4366-be1d-116196946154
All of the following are examples of time dependent late adverse drug reactions except:
Glucocorticoid induced osteoporosis
Nitrate induced headache
Chloroquine induced retinopathy
Amiodarone induced tissue phospholipid deposition
1b
multi
null
Pharmacology
null
b8a1358d-556a-4ba9-bf9b-a9582ab186cf
Parasympathetic supply to lacrimal glands are passed through ?
Lesser petorsal nerve
Chorda tympani
Greater petorsal nerve
Lingual nerve
2c
single
Greater petorsal nerve
Anatomy
null
e5644567-4898-4102-bc78-fc1fe69b3583
Figure shows the mechanism of action of:
Vinblastine
Cisplatin
Imatinib
Trastuzumab
0a
single
Ans. (A) VinblastineThe mechanism shows the inhibition of polymerization of tubulin means the drug inhibit the spindle formation. This mechanism is shown by vinca alkaloids like vincristine and vinblastine.Mechanism on spindleDrugsInhibit polymerization of tubulinVincristine, VinblastineInhibit depolymerization of tubu...
Pharmacology
Chemotherapy: General Principles
4bf1d0cd-31ac-4ee5-afa8-9c833fed526b
IPC for criminal responsibility defining non-offence is ?
82
182
88
188
0a
single
Ans. is 'a' i.e., 82 Criminal responsibility:o Any act wrhich is done by a child under seven years of age is not an offence- Section 82 I.P.C.o A child between seven and 12 years is presumed to be capable of commiting an offence , if he attained ''sufficient maturity of understanding to judge the nature and consequence...
Forensic Medicine
Introduction to Forensic Medicine and Medical Jurisprudence
74f4ba73-f689-4afa-a3c6-1af0a81dcfa7
Standard method to differentiate between endotracheal and esophageal intubation is-
End tidal CO2
Chest X-rays
Auscultation
Paial pressure of 02
0a
single
Auscultation is the most commonly used method to detect endobronchial intubation. But it may be misleading, as breath sounds can be transmitted to opposite side of the chest. Chest x-ray is reliable but time consuming and expensive. The radio opaque marker at the patient end shoilube in the middle third of trachea. End...
Anaesthesia
Anaesthetic equipments
6d75ec18-2a9b-41fe-8f07-73bed181121c
True about vibrio cholerae is -
Disease more common in woman
Classical vibrio protect against development of 0-139 Tor is milder than classical
El - Tor is milder than classical
All
2c
multi
El - Tor is milder than classical
Microbiology
null
5277138b-7c95-4f8e-86a5-411f5372e1d6
The frequent mechanism in perforation of appendix is?
Impacted faecolith
Tension gangrene due to the accumulating secretions
Necrosis of lymphoid patch
Retrocaecal function
1b
single
Ans. is 'b' i.e., Tension gangrene due to the accumulating secretions
Surgery
null
9a1c3762-50ad-4897-95dd-34f70924dff3
All are ocular emergencies except
Diabetic Retinopathy
Bacterial endophthalmitis
Sympathetic ophthalmitis
Eye injury
0a
multi
Endopthalmitis, Eye injury, Sympathetic opthalmitis all present as ocular emergency. Diabetic retinopathy does not present as ocular emegency.
Ophthalmology
Retina
df24645a-022a-4587-84c7-1f56c57e22c3
Which glomerular lesion is seen in cases of reflux nephropathy
RPGN
MPGN
MGN
FSGS
3d
single
FSGS is seen in cases of congenital renal anomalies (unilateral renal agenesis or renal dysplasia) and acquited causes like reflex nephropathy.
Pathology
null
bf0a6633-9443-4eb3-bd97-19f6fb10ac92
A 25 year old colonscopy showed pigmentary deposits and microscopy showed pigment laden macrophages. The women in on laxatives for past one year. Which of the following is the cause of it ?
Castor oil
Bisacodyl
Lactulose
Senna
3d
single
Ref. KDT. Page. 677. Senna is obtained from leaves and pod of certain Cassia sp., while Cascara sagrada is the powdered bark of the buck-thorn tree. These and a number of other plant purgatives contain anthraquinone glycosides, also called emodins. Senna is most popularly used. MOA – They not active as such. Unabsorbe...
Unknown
null
f215ca57-e3e3-4e11-8919-f567ee4af81b
H type endodontic instrument has a spiral edge arranged to allow cutting during
Pushing stroke
Pulling stroke
Circular stroke
Oblong stroke
1b
multi
null
Dental
null
59c271a3-d6d7-44a8-b4b8-23510e08b0fd
All are features of ileocecal tuberculosis except?
Pulled Up Cecum
Fleischner Sign
Goose Neck Deformity
Wind-Sock Appearance of duodenum
3d
multi
* Wind Sock Appearance of Duodenum is seen with intraluminal diveiculum of duodenum. Goose neck deformity occurs due to contracted, cicatrized, and pulled-up cecum as well as straightening of the terminal ileum seen in ileocecal tb . The 'Fleischner sign'(also known as the 'inveed umbrella sign'), refers to a widely ga...
Radiology
Gastrointestinal Radiology
a68a6c5c-4984-4a3b-b985-c57ebd2a300e
Acid susceptible penicillin is?
Methicillin
Ampicillin
Amoxicillin
Cloxacillin
0a
single
null
Pharmacology
null
ccb58bf0-ee5d-4658-a936-a3ac446342af
Fracture shown in this radiograph is:
Colies' fracture
Smith's fracture
Bennet's fracture
Rolando's fracture
2c
single
Ans. C Bennet's fractureThere is a 2-part fracture of base of thumb (first metacarpal) with intra articular extension. Similar intra articular 3 part or comminuted fracture is known as Rolando's fractureQ. Abductor pollicis longus tendonQ - creates an un-opposed pull on the fracture fragments hence Bennet's fracture re...
Radiology
Skeletal System
16892598-11eb-4174-baa4-1faa4d47a0e3
The following are the features of β thalassemia major except –
Bone marrow hyperplasia
Hair–on–end appearance
Splenomegaly
Increased osmotic fragility
3d
multi
null
Pediatrics
null
4249a6e5-a636-4f61-94d4-b81d00c8bb8d
Chronic Cor pulmonale is seen in all except:
Pulmonary embolization
COPD
Cystic fibrosis
Primary pulmonary hypeension
0a
multi
Answer is None or A (None or Pulmonary embolization): Recurrent pulmonary embolization leads to chronic cor pulmonale, but the question does not mention 'Recurrent' and hence this is the single best answer of exclusion COPD, Cystic Fibrosis and Bronchiectasis may all progress to chronic cor pulmonale Etiology of Chroni...
Medicine
null
358e4e5e-b218-4939-b296-545e45a6838c
According to WHO, membranous glomerulonephritis seen in SLE, is-
Class II
Class III
Class IV
Class V
3d
single
Ans. is 'd' i.e., Class V KIDNEY INVOLVEMENT IN SLE (LUPUS NEPHRITIS) A. Glomerular disease There are several versions of WHO classification of lupus nephritis ? 1. Minimal or no detectable abnormalities (class 1) o It occurs in less than 5% of patients. o Has best prognosis. 2.Mesangial lupus glomerulonephritis (class...
Pathology
null
ff8e5916-27fc-4415-9b63-3b8cb5d3dfc0
Ouchterlony procedure is a immunodiffusion by
Single diffusion in one dimension
Double diffusion in one dimension
Single diffusion in two dimensions
Double diffusion in two dimensions
3d
single
Single diffusion in one dimension - Oudin procedure Double diffusion in one dimension - Oakley fulthorpe procedure Single diffusion in two dimensions - Radial immunodiffusion Double diffusion in two dimensions - Ouchterlony procedure
Microbiology
null
604f92a1-1e5c-4a86-aa51-eb334621a345
Formation of Okazaki fragments occur in
Transcription
Translation
Transduction
Replication
3d
single
In molecular biology, DNA replication is the biological process of producing two identical replicas of DNA from one original DNA molecule. This process occurs in all living organisms and is the basis for biological inheritance. DNA is made up of a double helix of two complementary strands. During replication, these str...
Biochemistry
Metabolism of nucleic acids
05abf886-a2c5-4d33-b18c-d889b19d59af
The earliest change seen in apoptosis is -
Cell shrinkage
Pyknosis
Formation of apoptotic bodies
Fragmentation of cells
0a
single
Ans. is 'a' i.e., Cell shrinkage Morphological changes in apoptosiso Features of apoptosis areCell shrinkage : It is the earliest changes. It is due to damage to cytoskeleta! proteins.Chromatin condensation (pyknosis)/nuclear compaction : It is the most characteristic feature.Formation of cytoplasmic blebs : It is the ...
Pathology
Apoptosis
fb7ddcc7-8782-4d38-aca1-e2b909f9b831
Methemoglobinemia may be caused by following agents, EXCEPT:
Sulfonamides
Phenytoin
Phenacetin
Phenazopyridine
1b
multi
Drugs Commonly Implicated in Patients with Methemoglobinemia: Analgesics Phenazopyridine Phenacetin Antimicrobials Antimalarials Dapsone Local anesthetics Benzocaine Lidocaine Prilocaine Dibucaine Nitrates/nitrites Amyl nitrite Isobutyl nitrite Sodium nitrite Ammonium nitrate Silver nitrate Sulfonamides Ref: Farmer B.M...
Pharmacology
null
08295e22-9c86-44a2-bd94-3621b9925304
Which of the following results in bitemporal hemianopia?
Craniopharyngioma
Optic nerve glioma
Posterior cerebral aery occlusion
AION
0a
single
- Tumors of the pituitary body are MCC of bitemporal hemianopia, Suprasellar tumors like: Craniopharyngioma and Suprasellar meningioma also results in bitemporal hemianopia
Ophthalmology
Neuro Ophthalmology
19ed27fd-fd34-42b1-8023-49e357e5c8fc
Which of the following statistics should be adjusted for age to allow comparisons-
Age specific feility rate
Crude moality rate
Perinatal moality rate
Infant moality rate
1b
multi
Crude death rate is adjusted on the basis of age to obtain "Age adjusted or standardised death rates". Advantage of age adjusted standardised death rates is that, it removes all the confounding effects of different age structures and yields a single standardised adjusted rate, by which the moality experience can be dir...
Social & Preventive Medicine
Epidemiology
d8d03fd7-8092-48ab-a94c-8eeda2d7131a
Marker of lysosome is: (Repeat)
Acid Phosphatase
Lactate dehydrogenase
Oxidase
Na K ATPase
0a
single
Ans: A (Acid Phosphatase) Ref: Harpers illustrated biochemistry, 28th edition.Explanation:Markers of Intracellular organellesPlasma Membrane: Na+ K+ ATPase & 5' NucleotidaseCytoplasm: Lactate dehydrogenaseMitochondria: Glutamate dehydrogenaseRibosome: RNAEndoplasmic reticulum: Glucose-6 phosphataseLvsosoitie: Acid phos...
Biochemistry
Enzyme Specificity and Allosteric Regulation
9ff0bba2-2cad-4086-a7f2-cfa018876e19
Non professional antigen presenting cell is A/E –
Red blood cells
Endothelial cell
Epidermal cell
Fibroblasts
0a
single
Non-professional antigen presenting cell o A non-professional APC does not constitutively express the Major Histocompatibility Complex class II (MHC class II) proteins required for interaction with naive T cells; these are expressed only upon Stimulation of the non- professional APC by certain cytokines such as IFN-γ. ...
Pathology
null
0af5c147-be0b-4fb9-94a4-9d14e9bcb752
Following MRM parasthesia develops due to involvement of which nerve
Long thoracic nerve
Medial pectoral nerve
Brachial cutaneous nerve
Thoracodorsal nerve
2c
single
.Complications of MRM/mastectomy * Injury/thrombosis of axillary vein * Seroma--50-70% * Shoulder dysfunction 10% * Pain (30%) and numbness (70%) * Flap necrosis/infection * Lymphoedema (15%) and its problems * Axillary hyperaesthesia (0.5-1%) * Winged scapula LYMPHANGIOSARCOMA (Stewa-Treve's syndrome) of upper limb ca...
Surgery
Endocrinology and breast
c35ec938-5003-4209-862a-0c025fd5a2dc
The lung abscess in children can be caused by all except-
Pneumococcus
E. Histolytica
Staphylococcus
Klebsiella
1b
multi
Ans. is 'b' i.e., E. Histolytica Lung abscess in children Lung abscess are most likely to occur in - i) Immunocompromized patients ii) Those with recurrent aspiration v) Complication of pneumonia iii) Malnutrition iv) Blunt chest trauma Organisms commonly causing lung abscess are - Staph. aureus S. pneumoniae Pseudomon...
Pediatrics
null
80f36239-e22c-4d02-a531-6331fb4d40ad
Deltoid is supplied by -
Suprascapular nerve
Axillary nerve
Upper and lower subscapular nerves
All of the above
1b
multi
null
Anatomy
null
40622c2c-896f-4b06-9e2c-1353771e665f
Forceps are preferred over vacuum for the delivery because of the following reasons except
Vacuum requires more clinical skills than forceps
Vacuum is preferred more than forceps in HIV patient
Forceps are more commonly associated with fetal facial injury
Vacuum has more chance of formation of cephalhe matoma
0a
multi
Ans. a. Vacuum requires more clinical skills than forceps
Gynaecology & Obstetrics
null
a13ec6a5-7898-4438-9604-250d042feba7
Soft friable extradural hematoma with honeycomb appearance seen in autopsy in cases of death due to -
Coagulopathy
Thermal injury
Post moem trauma
None of the above
1b
multi
Reff: The synopsis of forensic medicine& Toxicology 28th edition pg: 167 Heat hematoma: Heat hematoma is soft, friable clot that is pink in colour and shows honeycomb appearance. It is 2-15 mm thick and contains 100-120 ml of blood. Characteristic feature of thermal injury.
Forensic Medicine
Thermal injury
5809008f-8182-4a8f-b331-6ea6e9389524
An infant presents with cardiac failure. Examination reveals a weaker femoral pulse when compared to the radial pulse. What is the probable diagnosis?
PDA
COA
Aorto-illiac vasculitis
VSD
1b
single
Ref: Nelson's Textbook of Pediatrics. 19th Edition.Explanation:Weak femoral pulse is indicative of Coarctation of aorta. Normally, the femoral pulse occurs slightly before the radial pulse. Weak femoral pulse or femoral pulse felt after radial pulse is a characteristic feature of COACoarctation of aorta (COA)Constricti...
Pediatrics
C.V.S.
30a41374-7029-4b43-8833-a79c01534c00
First cell in RBC development is
Proerythroblast
Intermediate normoblast
Reticulocyte
Basophilic erythroblast
0a
single
.
Anatomy
All India exam
5610fcc1-8b3b-4e68-850f-938c91636041
The mineral having sparing action on vitamin E
Calcium
Iron
Iodine
Selenium
3d
single
The element selenium  is found in the enzyme glutathione  peroxidase  that  destroys  free radicals.  Thus, Se is also involved  in antioxidant functions like vitamin E, and both of them act synergistically.  To a certain extent, Se can spare the requirement  vitamin E, and vice versa. Ref : Satyanarayana, 3rd ed, pg. ...
Biochemistry
null
d5f38713-e153-4a60-887a-17d84cb5efba
If a completely radioactive double stranded DNA molecule undergoes two rounds of replication in a solution free of radioactive label. What is the radioactivity status of the resulting four double stranded DNA molecules
50% of the DNA molecules have no radioactivity
2 DNA molecules have radioactivity in both strands
I DNA molecule has radioactivity in both strands
All 4 DNA molecules have radioactivity
0a
multi
DNA replication is semi conservative. Thus 2 DNA molecules have one strand with radioactivity and other 2 DNA molecules have no radioactivity.
Biochemistry
null
cccd3ad8-9dea-4d10-8536-812bae6afa6c
Effect of environment on genes is called –
Positive Eugenics
Negative Eugenics
Euthenics
Enthenics
2c
multi
Eugenics Science which aims to improve the genetic endowment of human population. That is improving the quality of the human species or a human population by genetic manipulation. Eugenic may be : Negative →        Discouraging reproduction by persons having genetic defect or presumed to have inheritable undesirabl...
Social & Preventive Medicine
null
620c91fc-2b3d-4b89-abc6-1673fec306e9
What should be measured in a newborn who presents with hyperbilirubinemia –
Total & Direct bilirubin
Total bilirubin only
Direct bilirubin only
Conjugated bilinibin only
0a
single
Bilirubin is a tetrapyrrole and a breakdown product of heme catabolism. Most bilirubin (70%-90%) is derived from hemoglobin degradation and, to a lesser extent, from other hemoproteins. In the serum, bilirubin is usually measured as both direct bilirubin (DBil) and total-value bilirubin Direct bilirubin correlates with...
Pediatrics
null
7232e19d-de66-4284-8dce-7bcd3261f14c
Which of the following gene defect is associated with development of medullary carcinoma of thyroid?
RET Proto Oncogene
Fap gene
Rb gene
BRCA 1 gene
0a
single
Activating point mutation in the RET proto oncogene plays impoant role in development of both familial and sporadiac medullary carcinoma of thyroid. The tumour tissue is firm,pale grey to tan and infiltrative. On microscopy,stroma shows acellular amyloid deposits which are derived from calcitonin polypeptides. Ref: Rob...
Pathology
Endocrinology
f4470ff9-6011-4f8c-b523-6844ae8c14f7
21 yearold female presents with history of mild bilateral ptosis, proximal muscle weakness and easy fatiguability. Which amongst the following, is best in diagnosing this condition: March 2013 (b)
Muscle biopsy
Edrophonium test
Repetitive nerve stimulation test
Electromyography
1b
single
Ans. B i.e. Edrophonium test Myasthenia gravis Decreased myoneural junction transmission Features: Dysahria, Dysphagia, Proximal muscle weakness, Sensory modalities and deep tendon reflexes are NORMAL MC used cholinergic drugs: Pyridostigmine/neostigmine Surgical procedure (should be done in all cases): Thymectomy
Medicine
null
124eeb8e-f3f6-4a74-ab5b-3f023cd2e4ed
Investigation of choice for evaluation of acute head injury: AIIMS 14
CECT Head
NCCT Head
MRI Brain
CT Angiography
1b
single
Ans. NCCT Head
Forensic Medicine
null
65e8b791-212e-4510-978f-99b42faeb4a2
A 19-year-old G2P1 woman at 9 weeks' gestation presents to the obstetrics and gynaecology clinic for her second prenatal visit. She reports no complaints other than occasional nausea. She had her first child by spontaneous vaginal delivery without complications. She is taking no medications and denies ethanol, tobacco,...
Despite the potential for fetal infection , she may opt out from the test
Early retroviral therapy will absolutely decrease the chances of transmitting infection to the baby.
CDC recommends screening only for patients with high risk factors
Risk of the test include potential for fetal loss.
0a
multi
The CDC and ACOG (2008) has recommended prenatal screening for HIV using an “optout approach” this means that the woman is notified that HIV testing is included in a comprehensive set of antenatal tests, but that testing may be declined. Women are given information regarding HIV but are not required to sign a specific ...
Gynaecology & Obstetrics
null
436d5ebb-a725-40a5-85b7-339a8b0f9e89
All are indicated in a patient with cystinuria with multiple renal stones except
Cysteamine
Increase fluid intake
Alkalinization of urine
Penicillamine
0a
multi
Ans. a. Cysteamine Patient with cystinuria with multiple renal stones should be treated with increase urine volume (high fluid intake), alkalinization of urine Penicillamine and tiopronin. Cystinuria (AR) Inheritance: Autosomal recessive Molecular defect: Shared dibasic cystine transpoer SLC3A1, SLC7A9Q Tissue manifest...
Medicine
null
702a4b32-1309-485d-8dbd-2fd8b8211ce8
Whip lash injury occurs in
Pedestrian hit from front
Pedestrian hit from behind
Occupant of a car
Any of the above
2c
multi
Whiplash injury In Road traffic accidents, involving acceleration/ deceleration trauma. commonly sustained by the front seat occupant of a car with no or poorly adjusted head rest Sudden hyperextension & then hyperflexion of neck occurs Resulting in fatal contusion or laceration of spinal cord without fracture of spine...
Forensic Medicine
Regional injuries
fdadb427-773c-4cc4-9241-aa5a99c52d90
Vesicoureteric reflux is best demonstrated by:
Intravenous pyelography
Micturating cystourethrogram
Retrograde pyelography
Isotope renography
1b
single
Ans. Micturating cystourethrogram
Radiology
null
a32b791b-2254-44fd-8dca-062aeed41c20
Which of the following is the commonest site of fibroma?
Labia majora
Labia minora
Clitoris
Rudimentary hymen
0a
single
Fibroma is a rare benign tumor of the vulva arises from deep connective tissues by fibroblast proliferation. Lesions are primarily found on the labia majora. Larger lesions often become pedunculated with a long stalk and may cause pain or dyspareunia. Surgical excision is indicated for symptomatic lesions. Ref: Hoffman...
Gynaecology & Obstetrics
null
4cab72ee-ecbd-4521-9a44-b3cbd054c058
Biosafety precaution grade III is practiced in all of the following organisms except ?
Human influenza virus
St. louis encephalitis virus
Coxiella burnetti
Mycobacterium tuberculosis
0a
multi
Human influenza virus is Biosafety grade II virus
Microbiology
null
2b8374f3-8384-4b8e-a999-32b8efde94b8
Nasal mucosa is supplied by:
only external carotid aery
Only internal carotid aery
Mainly external carotid aery
Mainly internal carotid aery
2c
single
Both the internal and external carotid aery supply the nose but main aery is the external carotid aery. Ref.Dhingra5/e p 189
ENT
Nose and paranasal sinuses
e58e5138-6a4e-46d8-a20b-92c14a991dc7
In coronary bypass graft surgery of a 49-year-old female, the internal thoracic aery is used as the coronary aery bypass graft. The anterior intercostal aeries in intercostal spaces three to six are ligated. Which of the following aeries will be expected to supply these intercostal spaces?
Musculophrenic
Superior epigastric
Posterior intercostal
Lateral thoracic
2c
single
The anterior intercostal aeries anastomose with the posterior intercostal aeries. Ligation of the anterior aeries would not affect the supply of the intercostal spaces because the posterior aeries would provide collateral aerial supply. Branches of the musculophrenic aery provide supply for the lower seventh, eighth, a...
Surgery
Thorax And Mediastinum
13256dea-5dc7-4fb2-bfa3-5e0ac4408575
Patent vitello-intestinal duct should preferably be operated at:
Bih
6 months of age
12 months of age
3 years of age
1b
single
Patent Vitello-intestinal Duct The resulting umbilical fistula discharges mucus and rarely, feces A patent vitello-intestinal duct should be excised, together with a Meckel&;s Diveicula if present, preferably when the child is about 6 months old Ref: Bailey 27th edition Pgno : 1044
Surgery
G.I.T
6358f295-0a9e-440c-bb79-5f496891613c
A 28 year old female comes to you with history of oligomenorrhea. On examination you note hirsutism and virilisation. USG showed that the left ovary is enlarged. The testosterone levels comes as 4 ng/ml. What is the MOST probable diagnosis? Note: The LH levels are normal.
PCOS
Stromal hypehecosis
Luteoma of pregnancy
Ovarian tumor
3d
single
PCOS is associated with elevated LH and mildly elevated testosterone. In case of stromal hypehecosis, though testosterone is elevated and LH is normal. Markedly elevated testosterone > 2 ng/ml is suggestive of tumor. Ref: Essentials of Gynaecology by Lakshmi Seshadri, Edition 1, page - 254.
Gynaecology & Obstetrics
null
897b5be0-a6c7-4025-985c-43af58e296eb
Pale waxy umbilicated swelling on the lid is
Chalazion
Molluscum contagiosum
External hordeolum
Internal hordeolum
1b
single
Eyelid disorders Inflammatory disorders of eyelidsClinical pictureTreatmentBlepharitisSubacute or chronic inflammation of lid margins due to Corynebacterium, Staphylococcus aureus, Demodexfolliculorum&PhthiriasisPalpebraCrusts should be removed, Antibiotic ointment at least twice daily ( Erythromycin or tetracycline ),...
Pathology
All India exam
bf2adaf8-0465-4fbb-8a6d-85e7d6adba18
Which of the following is an oral thrombin inhibitor?
Rivaroxaban
Dabigatran
Argatroban
Alfimeprase
1b
single
Dabigatran etexilate is an oral thrombin inhibitor and rivaroxaban is an oral factor Xa inhibitor. Dabigatran etexilate is used as an alternative to warfarin for stroke prevention in patients with atrial fibrillation. Argatroban is a parenteral direct thrombin inhibitor. Alfimeprase is a fibrinolytic agent. Ref: Harris...
Pharmacology
null
fd8105f7-3a08-4cf9-83a2-285cf55cf38e
Killian dehiscence is seen in
Superior constrictor
Inferior constrictor
Middle constrictor
None
1b
multi
Inferior constrictor muscle has two pas:- (i) Thyropharyngeous with oblique fibers, and (ii) Cricopharyngeous with transverse fibers Between these two pas of inferior constrictor exists a potential gap called Killian&;s dehiscence. It is also called the gateway to tear as perforation can occur at this site during esoph...
ENT
Pharynx
a114573c-cb80-47bc-b5ab-4d5460e84896
Cataract is caused by ?
Hypoparathyroidism
Cigrate smoking
Non-ionizing radiation
All of the above
3d
multi
Ans. is 'd' i.e., All of the above
Ophthalmology
null
08ed2984-6c2d-4a55-b57c-ac67128dff7d
NOT true about co-relation is-
Doesn't tell about causation
Tells about risk of the disease
-1.0 correlation shows linear relationship
Tells association between two variables
1b
multi
Ref:Parks 23rd edition pg 852 In order to find out whether there is significant association or not between the two variables , coefficient or Corelation is calculated . r lies between -1 and +1 r near -1 : indicates strong negative correlation . r = 0 : indicates no association r near +1: indicates strong positive corr...
Social & Preventive Medicine
Biostatistics
a358d9e6-0906-43e1-b9e7-9cf1cbe84cb5
Anti-ds DNA antibodies are most specific for
SLE
Rheumatoid ahritis
Scleroderma
Polymyositis
0a
single
The best screening test for SLE is a demonstration of Antinuclear antibodies (ANA) Sensitive test for SLE ANA Specific test for SLE Anti-ds DNA and Anti Sm antibody Ref - Harrison's internal medicine 20e pg 2515, 2516f, 2517t, 2518t, 2522
Medicine
All India exam
e3fa7c77-8455-46ec-8b5f-64a206e20a86
Pruritus precedes jaundice in
Primary biliary cirrhosis
Secondary biliary cirrhosis
Primary sclerosing cholangitis
CBD stone
0a
single
Primary biliary cirrhosis Believed to be an autoimmune etiology, leading to progressive destruction of intrahepatic bile ducts More common in females Associated with autoimmune disorders (CREST, Sicca syndrome, Autoimmune thyroiditis, Renal tubular acidosis) Clinical features Most patients are asymptomatic, pruritus th...
Anatomy
G.I.T
b2c5c01e-a574-4599-9c58-f5826495d393
Esthesio neuroblastoma arises from -
Olfactory N
Maxillary N
Ophthalmic N
Nasociliary N
0a
single
Esthesioneuroblastoma or olfactory neuroblastoma are uncommon highly malignant tumors, arising from the neuroendocrine cells in the olfactory mucosa. Ref : Osborn Neuroradiology 1/e p493
Surgery
Head and neck
d28834f0-9f2f-44f9-b12a-964a11dae419
All of the following blood vessels are a part of Kiesselbachfs plexus except-
Anterior Ethmoidal artery
Posterior ethmoidal artery
Greater palatine artery
Superior labial artery
1b
multi
Ans. is 'b' i.e., Posterior ethmoidal artery o Four arteries contribute to little's area:# Anterior ethmoidal artery# Septal branch of superior labial artery (Branch of facial A).# Septal branch of sphenopalatine artery (Branch of maxillary A).# Greater palatine artery (Branch of maxillary A).o These arteries anastomos...
ENT
Epistaxis
e472cf4b-adc0-4723-b240-6037fda1dec8
Denominator in maternal moality ratio?
Mid Year Population
Live bihs
Total bihs
Total numbebr of pregnancies
1b
single
Maternal moality rate is total no.of female deaths due tobcomplications of pregnancy, childbih or within 42 days of delivery from puerperal causes in an area during a given year by total no.of live bihs in the same year and area.REF.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE.Editon-21.Page no.-514
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics